LOCUS       DADVXB010000001        56149 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.001, whole genome shotgun sequence.
ACCESSION   DADVXB010000001 DADVXB010000000
VERSION     DADVXB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.001"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            30..911
                     /locus_tag="KB902_000001"
     CDS             30..911
                     /locus_tag="KB902_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6806863.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            924..2534
                     /locus_tag="KB902_000002"
     CDS             924..2534
                     /locus_tag="KB902_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBB6806864.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAKGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2611..3270)
                     /locus_tag="KB902_000003"
     CDS             complement(2611..3270)
                     /locus_tag="KB902_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6806865.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3553..4218)
                     /locus_tag="KB902_000004"
     CDS             complement(3553..4218)
                     /locus_tag="KB902_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBB6806866.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4365..4970)
                     /gene="dhaL"
                     /locus_tag="KB902_000005"
     CDS             complement(4365..4970)
                     /gene="dhaL"
                     /locus_tag="KB902_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBB6806867.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(4998..6008)
                     /gene="dhaK"
                     /locus_tag="KB902_000006"
     CDS             complement(4998..6008)
                     /gene="dhaK"
                     /locus_tag="KB902_000006"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBB6806868.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(5983..6429)
                     /gene="dhaM"
                     /locus_tag="KB902_000007"
     CDS             complement(5983..6429)
                     /gene="dhaM"
                     /locus_tag="KB902_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBB6806869.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6532..6852
                     /locus_tag="KB902_000008"
     CDS             6532..6852
                     /locus_tag="KB902_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBB6806870.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6964..7833)
                     /locus_tag="KB902_000009"
     CDS             complement(6964..7833)
                     /locus_tag="KB902_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6806871.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(7929..9233)
                     /locus_tag="KB902_000010"
     CDS             complement(7929..9233)
                     /locus_tag="KB902_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6806872.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9230..9739)
                     /locus_tag="KB902_000011"
     CDS             complement(9230..9739)
                     /locus_tag="KB902_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806873.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9914..12049)
                     /locus_tag="KB902_000012"
     CDS             complement(9914..12049)
                     /locus_tag="KB902_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6806874.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12132..13787)
                     /locus_tag="KB902_000013"
     CDS             complement(12132..13787)
                     /locus_tag="KB902_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6806875.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13789..14103)
                     /locus_tag="KB902_000014"
     CDS             complement(13789..14103)
                     /locus_tag="KB902_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6806876.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14273..14533
                     /locus_tag="KB902_000015"
     CDS             14273..14533
                     /locus_tag="KB902_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBB6806877.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14547..14861
                     /locus_tag="KB902_000016"
     CDS             14547..14861
                     /locus_tag="KB902_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBB6806878.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15591..16145)
                     /locus_tag="KB902_000017"
     CDS             complement(15591..16145)
                     /locus_tag="KB902_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBB6806879.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16271..18200)
                     /locus_tag="KB902_000018"
                     /pseudo
     CDS             complement(16271..18200)
                     /locus_tag="KB902_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18506..19222)
                     /locus_tag="KB902_000019"
     CDS             complement(18506..19222)
                     /locus_tag="KB902_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6806880.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19223..21046)
                     /gene="glpO"
                     /locus_tag="KB902_000020"
     CDS             complement(19223..21046)
                     /gene="glpO"
                     /locus_tag="KB902_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBB6806881.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21060..22556)
                     /gene="glpK"
                     /locus_tag="KB902_000021"
     CDS             complement(21060..22556)
                     /gene="glpK"
                     /locus_tag="KB902_000021"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBB6806882.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22692..24152)
                     /locus_tag="KB902_000022"
     CDS             complement(22692..24152)
                     /locus_tag="KB902_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6806883.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24142..25437)
                     /locus_tag="KB902_000023"
     CDS             complement(24142..25437)
                     /locus_tag="KB902_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6806884.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25769..26446)
                     /locus_tag="KB902_000024"
     CDS             complement(25769..26446)
                     /locus_tag="KB902_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBB6806885.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26476..27567)
                     /locus_tag="KB902_000025"
     CDS             complement(26476..27567)
                     /locus_tag="KB902_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBB6806886.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27668..28102)
                     /locus_tag="KB902_000026"
     CDS             complement(27668..28102)
                     /locus_tag="KB902_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6806887.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28686..30143)
                     /gene="ascB"
                     /locus_tag="KB902_000027"
     CDS             complement(28686..30143)
                     /gene="ascB"
                     /locus_tag="KB902_000027"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6806888.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30140..32035)
                     /locus_tag="KB902_000028"
     CDS             complement(30140..32035)
                     /locus_tag="KB902_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6806889.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32093..33868)
                     /locus_tag="KB902_000029"
     CDS             complement(32093..33868)
                     /locus_tag="KB902_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6806890.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33918..35414)
                     /locus_tag="KB902_000030"
     CDS             complement(33918..35414)
                     /locus_tag="KB902_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6806891.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35608..37230)
                     /locus_tag="KB902_000031"
     CDS             complement(35608..37230)
                     /locus_tag="KB902_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6806892.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37558..38871)
                     /locus_tag="KB902_000032"
     CDS             complement(37558..38871)
                     /locus_tag="KB902_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6806893.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39116..39340)
                     /locus_tag="KB902_000033"
     CDS             complement(39116..39340)
                     /locus_tag="KB902_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806894.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39360..39782)
                     /locus_tag="KB902_000034"
     CDS             complement(39360..39782)
                     /locus_tag="KB902_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6806895.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(39924..40634)
                     /locus_tag="KB902_000035"
     CDS             complement(39924..40634)
                     /locus_tag="KB902_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806896.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40652..41149)
                     /locus_tag="KB902_000036"
     CDS             complement(40652..41149)
                     /locus_tag="KB902_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6806897.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41186..41638)
                     /locus_tag="KB902_000037"
     CDS             complement(41186..41638)
                     /locus_tag="KB902_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6806898.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41773..42378)
                     /locus_tag="KB902_000038"
     CDS             complement(41773..42378)
                     /locus_tag="KB902_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6806899.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42828..43448)
                     /locus_tag="KB902_000039"
     CDS             complement(42828..43448)
                     /locus_tag="KB902_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6806900.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43450..44319)
                     /locus_tag="KB902_000040"
     CDS             complement(43450..44319)
                     /locus_tag="KB902_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBB6806901.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44342..44749)
                     /locus_tag="KB902_000041"
     CDS             complement(44342..44749)
                     /locus_tag="KB902_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6806902.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44768..46057)
                     /locus_tag="KB902_000042"
     CDS             complement(44768..46057)
                     /locus_tag="KB902_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6806903.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(46084..46386)
                     /locus_tag="KB902_000043"
     CDS             complement(46084..46386)
                     /locus_tag="KB902_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6806904.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(46411..48504)
                     /locus_tag="KB902_000044"
     CDS             complement(46411..48504)
                     /locus_tag="KB902_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6806905.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(48993..49757)
                     /locus_tag="KB902_000045"
     CDS             complement(48993..49757)
                     /locus_tag="KB902_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBB6806906.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(49868..50737)
                     /gene="mdcB"
                     /locus_tag="KB902_000046"
     CDS             complement(49868..50737)
                     /gene="mdcB"
                     /locus_tag="KB902_000046"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBB6806907.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(50762..51838)
                     /locus_tag="KB902_000047"
     CDS             complement(50762..51838)
                     /locus_tag="KB902_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBB6806908.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(51862..52455)
                     /locus_tag="KB902_000048"
     CDS             complement(51862..52455)
                     /locus_tag="KB902_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBB6806909.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(52459..54135)
                     /gene="mdcD"
                     /locus_tag="KB902_000049"
     CDS             complement(52459..54135)
                     /gene="mdcD"
                     /locus_tag="KB902_000049"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBB6806910.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(54125..54424)
                     /locus_tag="KB902_000050"
     CDS             complement(54125..54424)
                     /locus_tag="KB902_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBB6806911.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(54526..54936)
                     /locus_tag="KB902_000051"
                     /pseudo
     CDS             complement(54526..54936)
                     /locus_tag="KB902_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            complement(54936..56144)
                     /locus_tag="KB902_000052"
                     /pseudo
     CDS             complement(54936..56144)
                     /locus_tag="KB902_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        15812 a        11937 c         9614 g        18786 t
ORIGIN      
        1 atatttttag aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc acacatttga
       61 aaaagagctt tggtcgtttc gaagctttaa aagatgtctc tttcaccgta cattcaggtg
      121 aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc cacgacgatt cggacacttt
      181 tagggattat aaaaaaagac ggcggaacgg caacgatttt tgggcaagat gtatgggaag
      241 atagtttatc tatccatgaa cgtctttctt atgttccagg cgatatctct ttgtggggaa
      301 atttgactgg aggagcgatc atcgatctct tcatgaagct tcatggaaaa gggagtgctc
      361 aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc taagaaaaaa gcaaaaaact
      421 attcaaaagg aaatcgccaa aaagtgggct tgattgctgc tttggctgtt gattcggatc
      481 tctatttatt tgatgagcct acttctggtt tagatccttt gatggaaacg attttccaag
      541 aagaagttga aaaattgaaa gaacagggca aatccatcct actttcttct catattctca
      601 gtgaagtcga gcgactagcg gataaagtcg tgatcatacg cgaaggaaca ctcgatgaag
      661 aaggaacact cgatgaattg cgtcatttga ctcgttcgac catcactata gaaacagaag
      721 cagagaatag tcacttagca caattgaacg gtgtccatga ctttgtgcaa aaaggtcacc
      781 tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat tttagctgaa gcgtccaaat
      841 taggtgtgaa aaaatttgaa tctattccac cgactcttga ggatttattc atgagacatt
      901 atgaaggatg aggaggaagc gaaatgactg ataaattttc acgctggtcc accctttttt
      961 ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg gctagtcggt gtcactgctt
     1021 tttctggtgg ttttgtccct gcgtttgaag aattgacttc cggacaagga ttagctggat
     1081 tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt cggaccaact ccagcttcga
     1141 atgctgctga gtatacttta ggagcgatgt atgcaaatga aatgttgctt ttttgcagtt
     1201 tgtttgctgc tgtgatctct gttttacacg tggtgagcca aacgagaaaa aaagaagaac
     1261 ttggtctgat tgaacttatt cgttcctttc gagtcggacg tcaagcaaac tctttagctg
     1321 tcatcgctga aagtattctg atcaatttgc ttttagcaat atcgatcagc tgtacgatga
     1381 tttttttcca agcggattcg atcactgcaa aaggtgcttg gctttttggg ctatctgtag
     1441 gtagtatggg gattttgggg agtgccgttg cactgtttgc tgcacaactg atgccaagtt
     1501 cagccagttc gaatggtctg tctttagcgt ttttaggtgg actttacctt ctacgagcaa
     1561 taacagatgt agctgattcc tccctttcga tgtggaatcc tttaggctgg tcttatttga
     1621 cctatccatt tacaactaac aactggattc ctttgcttta tttgtttttg ttcagtctaa
     1681 tcttgataat cagttcattt gttttagagg aacatcgaga tttgaacacc ggctatatcc
     1741 ccgaacgtga aggaaaaccg tatgctaaac gttctctttt atccttgcgt ggtttattat
     1801 tctatctaaa taaagggatg acaatcagtt ggcttatcac ttttggtttg atgggggcgg
     1861 catacggctc tatctacggg aatatgcaac agtttttaga aagtaacgac ttaatgaaac
     1921 agatgtttat ccaatctggc gtctcaattg aaaaaaactt tacaagcacg atcatggtag
     1981 tcttgatttg tctagctgct attttaccaa ttgctagcat caatcgttta tttacagaag
     2041 aaacccacgg acgtatgaat cagctgttcg caacaaaaat ttctaggaac caactttatt
     2101 ggaccaatat gttactagct attctatttg ctatattggc aatcctgatt agttctggtg
     2161 cactagggct ttctgctttg gcttcgatga aggatgcgaa agacatggat ctattgatgt
     2221 ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt gtttatcgga attagtggct
     2281 ttctattcgg atggcttcct cgaatcggta aacttgctta tatctactta gcttactcct
     2341 ttgcactcaa ttactttggc ggaattttgg atttaccaga atggttttcc aaaacagctg
     2401 tccctagctg ggttccacgg atgccaaacg attcttttga tctttccgtg ttccttacgt
     2461 tatcatgtat cagccttgca ctgttcgtcc ttggttctat tggttatagg cgaagagact
     2521 tactagaagg ataataaaaa agcatgtaca atttcatgct agcctccaaa tctgggtcaa
     2581 aaatccaaca tttggaggtc atttttttat ttacaagtct tctaactgct ctttatcaat
     2641 gatccagact tctcgattct ttctttttac ataaccattc tcctctaata atttaaattt
     2701 tctagataaa gtttcggggg tcgtaccgat aaatgcagca agttctttca ttttcattgg
     2761 caggaaaaag tgatccttcc ctgtcgcttt agctaagtca agcagataga cagcgactcg
     2821 ttcttctact ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg ttaatttctc
     2881 aacgttgatt gctaaaagtt tcagactaag ggcgggataa tgcagtaaga gttccgagaa
     2941 atctttttgt ctcaatatgc aaatttccgt tttttctagt gcttcgccaa ataaagactc
     3001 atttggaacg cctagcaact ggctctctcc ctcatatccg cccggctcta ttactcgtaa
     3061 aagctgttcc tttccgctag cagataattg atacactttc atactgccgg aggccacgat
     3121 cactaattga ggttctccat tcggcgcaag aatctgttct cctttttcca catagtgatg
     3181 tttgacaagt gcgtgtactt tttcttgatc ttgctgtact aagtgattga acaaaggaac
     3241 aaatgaaaca cataaatgat catgactcat aatctctcct ccttctaaac agctatttct
     3301 aataaagaaa cataacttcc cttattccaa ctgataattt tcttttatca tagcataaac
     3361 gtcaagcgaa ccagatacca gcaaatagag tggatttctt tttgtccctt gctttatttt
     3421 ccttcttttg agaccttaag taattgattc ctatcaattt tttaaatatt tactttttga
     3481 ataatcaaaa acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt
     3541 atttcgtgtt gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc
     3601 ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag
     3661 tttacccatt tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt
     3721 atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca
     3781 tatgtaataa tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg
     3841 gttatacgct gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata
     3901 gatttggtat tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga
     3961 ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc
     4021 gattttaggt ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat
     4081 ctctttccat ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt
     4141 tggatggctc tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc
     4201 tgattttcca agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt
     4261 ttgcgatatg gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag
     4321 ccaaacaaaa aactgcgatg agcatcaccg cagttttatt gaacttaagg ttgattgatc
     4381 acatctaaaa gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc gatatgtccg
     4441 attgcacgct ctcctagata ggaagctcgt ccttttttag ctaccaagac tttggtgtgt
     4501 tcttttgcct ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc ctctgtgact
     4561 ggcagccaaa catctaacat cgttttatcg tcagcttctg cctttcctcg gctttgaata
     4621 cccgctgttc cctgctcgat cacttcgcct aatttttctt gagaatcaat agaatcgacc
     4681 tcttttgtcg ctttcatcat gttcatgaat gcagatccgt ataacggacc agaagcccca
     4741 ccgactttcg atatcatcgc catagagaat actttgaatg tatcgctgat tgtttcagga
     4801 tgatcggctt gaaaagcttc ttcataagct gaaacccctc ttcccatgtt atttccatgg
     4861 tctccatcgc caatcggggt atctagatca ctgagatatt gtttgttctg attgattgcc
     4921 tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat attatcaccc
     4981 ttttatcttg agatttttta ccatgaaatc gtctgtacat tgctttctaa agaatctttc
     5041 cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc tagtgaggtc
     5101 ataaaattac cgacttttcg gaaaactaca ttgacgcctc tttcttccaa cagagctaaa
     5161 acatcattca tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc gttgactagt
     5221 acacctgctt cttttggtaa attcgagtaa tcatctaaaa tcttagtaac aagttccttt
     5281 gccagtactt tagaaggctg catcttttct cgacgatagc ctggctcacc gtggatacca
     5341 acaccatact cgatctcatc ttctcctagt tcgaatcctg gtttccctac ttctggtaca
     5401 gttgctgctc gaagcgctag accgatcgtc ttagttgcct gtacgacctt ttctcccagt
     5461 tctttcaact cagctaggga agcaccgttt cttgctgcat cgcccacgat tttgtgtaca
     5521 aggacagtac ctgcaactcc gcgttttcca gcagtatacg tactattttc aacggcgata
     5581 tcatcatcta cgatcacact ttctacttca atatcgtcca tagcagctaa ttcctttgcc
     5641 atatcgaagt tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac tccttttcca
     5701 ctatcggctt ccttaatagc cgtctgaatc tgatctggag ttggagaagt aaacacatca
     5761 ccaagcaccg ctgcacttaa catcccttcc cctacaaacc cggcatggga tggttcatgt
     5821 ccgcttcctc caccagaaac caaaccaact tgttccgctt tctgattctt ggctacaaca
     5881 cgggaagatt ctacacgatg aacaagttct ggatagcttt ttactaatcc ttccagcatt
     5941 tcttcgacaa tattgcttgg atcattcatg atttttttca atttattccc atcctttctt
     6001 tccggcattt tgtgcttctg ttaagatttg ctgagtatca tctgttatac cggcagtgat
     6061 ggctgctgca aaagctcctt ccactaaagg cgcatccacc agatgataac gttgctgctg
     6121 ctcttcttcc aacatgtctt ttgccagttc cgagttcaat accgcgctac cgatatccgc
     6181 aaaaacaaaa taactagctg catcgcttga ttcattgact gcttctacga ttttcatcgg
     6241 gtctgatccg atctcgccat ttattccgcc gagagaaaaa atttgcacct cttcggattt
     6301 ttgcatctgc tcaatcattt ctttaatacc atctgttact ttttgactat gagaaataag
     6361 caaaatactt tttttcacaa gaatcttcct ttcttttaca tagttgctaa cgattggttt
     6421 cgctttcatt aatgaacaat tcaagtatat aataaatttc taattttggg aaaatatgtg
     6481 tagtgcttct tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg aatgattaca
     6541 acaacaacga acagtgtaga gggaaaagcc gtagtagctt ataaagggat cgtttttggt
     6601 gaggtcatta ctgggatcca tgcatttaaa gacttggagg cggggttgcg aaatatcttt
     6661 ggcggccgct caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga agcacttgcc
     6721 gaaatggccg aacgtgcaaa agcattagga gctgatgcga tcattggcgt aaaaatggac
     6781 tatgaagtat taggcagcga caatggcatg ctgatggtca catgtagtgg aacagctgtc
     6841 tccacgagat aagtagggga catctgtttt aataactaaa gagagatggg acatgtagtg
     6901 gcactcaaga attagatttt tcagtctaac ttcgaggtac tctaccttcc catcctctct
     6961 tttttatttc tttttgcgga tgattccgta agctgctgcg actaacacac ccgcccctgc
     7021 taaggaataa ctgacagaag ctgttttttc atttgttttt ggcaaagtct gacttgttga
     7081 tttggatggc tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg tcactgattt
     7141 ttctcctgcc gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta agtcagcttt
     7201 ttttgcttca aaatcattag caactgtttg tgcttcgctg atctttccgt ggattgcttg
     7261 actggccgct gtgatatccg cttgagtttg acttagcttt ccagaagctg tttgagcaac
     7321 ctgatttaat tgctgattga attcttttgc ttgttggatc ttcccgtcaa gatctgtttg
     7381 gacagcttcc gcttttgctt tcgcttcggc aagctttttc tcaagttgtg cacggtcatt
     7441 tcccacttta tttttaagat cagctaaatc ttgatcgatt gctgcttggt cttctttcaa
     7501 tttgtttttt gcagcttcta atgcttcttc gagttctttt cttttatttt ccaagtcttg
     7561 caaatgatcg atttggtcag aagaggtaga actatttatt gatgtatctt ctgaagatga
     7621 aatcgtttct cctgaattat ctgtcggtac attggaagtc atttctgttt ccgaggcacc
     7681 gttttcagca ccagaagagc ttatggttgt tgaaggttct gtttgagcag gttcagaagt
     7741 ttccgcaaaa gctgtctgtc ccaataagaa aatactggaa acagcaattg gccagattaa
     7801 cggcttcatt ctttttttca tcacttttcc catccttact actttttaac taatttctta
     7861 ttataagcaa aaatgtttgg aagaaccata aacacaacag gctgtttgtc taaaaaacgg
     7921 tgcatctttt atttttttgt acgttccggg cttttccatg tcccgcttcc ataacctaaa
     7981 atcgttttga ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac tatccagaac
     8041 aaaagcatat atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg atcatctaca
     8101 atcagcgaag ctagcaactg gaaaaatcct gcgaccattt caaagcagat gaacacaaaa
     8161 ctgaatgtaa aagtaatata aatctgttcg tagtttcctt gatatacata atgcccgatt
     8221 aatccagcaa aaagaactac ggaaatacaa aagaatattg accagacaat actcaatgtt
     8281 tgatcaatga agatgatcgt tcttccaata tgtttaaaag gatggagcat cacttttttg
     8341 aaattcgtca gccagacttc tgttccacct tttgcccaac gttttctgtg tcgatatagc
     8401 atcttcaacg tcacaggtac ttccatgaaa aagataatct caggagcaaa aacagataac
     8461 cagtcattta actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg atcttgtctg
     8521 aatccgccca catcgatcaa ggcttctttt cgatacatcg tatttgctcc actgtacgca
     8581 taaagaccac cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat acttgagaat
     8641 tcaaccgttt gagattttgc aatcaatttg gtacgatttt ggacatccat atttgcagtg
     8701 accgcagcaa tatgtcttgc accagggcga atgaaataat tcacatacct aatcagtgca
     8761 tctggctccg gtaccgtgtc tgcatcattg cttaaaatca atttcccttt tgcaaaggca
     8821 agtccgatat taaacgcgtg ggcttttcct ttattttttt cgatccgaac cacacgaaga
     8881 ttagcgtatt ttttcatcag tctagctaat atttctggtg tttggtccgt tgaaccatcg
     8941 tctgtcacta atacctcata gttgtgataa ttcaatttcg tcatcaaata ctcgattgta
     9001 tattcgatca caatttcttc attatgggct ggcaccatga tcgtgatgaa cggttcgaca
     9061 ctcaagggaa catctaccca ttctttttgc ttatgtttgt ataaaaacac ataacaccag
     9121 acaccaataa accatacaaa tccgcctaaa atcggataag aaacgagaaa aaaatacata
     9181 atagacaaac aagtatctaa gaataaatta cctgtatggg tgattgagat catttcagtt
     9241 ccaccccatt ttctttatac aaatctgcaa tgaatgtcgt atctagattt ttctcttcgg
     9301 agacagaata aaaacggacc gtttctctct cttcttttgt tccaaaacgt tccgtataca
     9361 cttcttcaag taattcttgt ctttttttca atttttcatc ttcatattca aaagatttat
     9421 ttactttttt gtatagattt cgattgttcc acctagtcaa tacaaatgag gtaatcagga
     9481 aactgaaaaa aatcaataca aaaaagccga ttaagaaata cagcattttc ttttctgata
     9541 aaaaagcgta caaggaaaaa tccttggctc tttctggtct cgttaatggg aaaaagaccc
     9601 atataaaagg aagaacaacg atcatccatc ctaaaagagc cactaacgtt tgccaaatct
     9661 ttaaccagta attacctttt gaaaaatact tatctttcac caaaattgat gcaacttctt
     9721 ctcttgttac ttttttcata tcctcacctc acgttttttt gttacgacgt aggagtttac
     9781 catacatttc atttcttttc acataaagtg ttcctaaatt tttcctaaga aaaagaacaa
     9841 aacatttctc atcagcaaat gaaaaatatt ttgttctttt tatcagttgt tctttttatt
     9901 ttttatctct taattatgtt gctctttcca atacgacaat gcttttcatt cctctagata
     9961 tcgccgtgta catttgtctg cgtcttcttt gctcatctcc atcgttttca aatggatata
    10021 agattacatg atcaaattcc agtccttttg ctagactcaa aggaatgatt tggcagtttt
    10081 ctaatccata tgaatttttt ttaatcgatt cttgtagcgt ttgggtttcc tcttctgttt
    10141 gggtgataac tgccgctttt tctcctttta gagaaaccaa aatctcagct agtattttca
    10201 acaattcttc agaggatcga aaagagcggt attcgggttc ttttccttgc ggtcggatcg
    10261 atacgatgtc gatcttctct tgatccacag cataggtttt gaaaagctct gtgattgctc
    10321 cgctagaacg gtaactattt ctaagatcat accgatggat cggcagatgg tagtcgtcga
    10381 aacaacgcat aatatcagca aaagtagtgg aagaattaaa gattgcctga ttctcgtcac
    10441 ctactaaagt aaagtgagtt tttggaaata attcgatcaa tagacctaat tgtgccaggg
    10501 tataatcttg tacttcatca atcaatagat agcgaaatgc tggtacattt accttttcaa
    10561 caagtaaatg acgaatagct aatataatga ctgcttcatc aacagtacgt gtgggttgcc
    10621 aagcataagc tgagccatat cgtttttcat aaattctttc aaacaactga tgctcatcca
    10681 cccatgccat ttcttcgatt tgtctggtta tttttcgata ttttttttgt aaaagtttcc
    10741 ttgcataagc tacaatactt tgttccgaat catcagaaat caatttaccg aataattcca
    10801 actgcctatc ttctgtcaac gagagtacct gattctgcac agcaggactt tttgcttgtt
    10861 tcaaaagatg attcttccat tcgctcatca gtgccttttt cgttgcttga agcctatcga
    10921 tcaatttagg atgagcagga actttctcat atattttttc gatcgttttt ttagaaagga
    10981 ctgtttttcc atttttagta agtccacgga taaaattcgg atgatctaaa aacaaaggat
    11041 ctgattgttt tagattatcg ataaactttt tgctacgcaa acgttctgtc tgctccgata
    11101 cattttctcc cgtgatacgt ttgaaataag cctcttcacc ttctatttcc tctgctgaaa
    11161 gctgtgaaac cagctgtatg atggttagat tcagtggatt tctttcacct aatgatggta
    11221 ggacattcga aatatagtcg ataaaccgat gattaggtga tagaatcagc aagtcatcgg
    11281 atgtcatcgt atctcgatat aaatagagca gatacgcaat acgctgcatg atagcagagg
    11341 ttttaccact tcctgctacg ccatttacca agatattttg acttttcaca tcccgaatga
    11401 ttgtgttttg ttccgattgg atcgtagcag tgatagcctt catttcattg gtctcatctt
    11461 ggcctaagac ttctaataat acgtcatctt gaatagctac agacgtatca aaaaacttga
    11521 ccaaacgatc tctttccaaa agaaattgtc gtctttcttt aataaccgta tcgattttat
    11581 tttgacgaac cgtataagaa gatggaccaa tcatgttatt gtaaaaaagt tcggcaattg
    11641 gtgaacgcca atcataaaca agattttcat ctgcatcatc tgtgaaattt gctgtaccga
    11701 tataaaagga ttcttttggc tcattatcca gaaagtctac aacgactttt ccaaagtagg
    11761 gacttttcaa taaacgttcg atctttgcta gctgattttc tgcgtttttc tgtttgatat
    11821 tcatctgatc gatttctcta tttttcattt caatcatcga aaaagtatcc aggttatcta
    11881 agtaactgtc aaaattcaat cgaagctcgc cagccatttc tttcaacgac tggtttcctt
    11941 ctatttttgc cgtatccatc gattcccgca gttcgttttt tttatcaatt agcttttgat
    12001 acacgttctt cagatatgct tcttctaact gtttttgtgt gttgaccata cacattctcc
    12061 tcttttttta aagtggtgga accgattagt ttacctcttt taagagtcga atgcaagctt
    12121 tttaacgagt atcatttgtt aggatatatc agttcttcag gtcggacagt ttgatataaa
    12181 gaaaatgcac catcaaggtt ttttacgtgg tagccagact gcttcaagat tctttccgct
    12241 agatagctac gtaatccgct atgacagctg acgatatatt cttgttggct gtctaattca
    12301 tttaatcggt cccgaagttc attcaaaggg atatgtttgg cttccttgaa tttgcccttt
    12361 tccaattctt ctgctgttcg cacatctaat aaaatttttc cttttgctag ttctgtcggc
    12421 aattcatgcc attgtacggt ttcactaagc ccttctgcaa tgttcattgc tgcatatcct
    12481 agcatgttta ctggatcttt ggctgagcca aatggcggtg catacgtcaa ttctaattcc
    12541 ggtaaatcga agatcgtcaa atgccctttg attgctgttg ctaaaatatc gatccgttta
    12601 tccacacctt ttgccccaac accttgtgca ccataaatct cgccagtctc tggatggaag
    12661 atcaacttca gtaaaatatc tgttgcttct ggataatagc ttgcatgatc ttttcctgat
    12721 acatgaatga cttcaaaaga cagttcgttt tctttggctg ttctttcact taaaccggtg
    12781 gatgcggcag tcattccaaa cgttcgtata attgctgttc caataccgcc ttgatttctt
    12841 cgagaaattc cggaaatcgt gtccgcaact tgtctacctt gacgattggc tggtgaagca
    12901 agagaaataa gtgcatcttt tccagtgatt tgctgtttta caacgatagc atcccccacc
    12961 gcataaatat caggaatatt cgtttgataa cgttcgtcta ctaggatacc cccgcgtatg
    13021 cctaattcga ttccagcggt cactgctagc tggttatcag gacgaacacc aatggataaa
    13081 ataactaaat cagcagggat ggtacgccca tcatccagtc gcaatcgttt cccgtggtct
    13141 tcaaatccag cgacagcatg agaagtaatc acttctactc cttgatgaga caattctttt
    13201 tctataaaag ctgccatttc ttcatccagt gttggaagaa tatgtggtgc ttgttcgatc
    13261 accatgactt ctaaacctct tctttttagg ttttctgcca tttccaatcc gatgaatcct
    13321 gcaccaacga tcacggcacg ctttggctgt ttttctaatg catgcatcac tttatcgata
    13381 tctggtacat ttctaataga aaaaacattg tcggcttctg ttatccctgg aatcgatgga
    13441 acaactggtt ttgcaccagg agataaaacc aatgcatcgt actgttcaat gtgtttttga
    13501 ccctcatgta cgacttctac cgttttgttt tcgggaaaga tggctgtcac ttcatgattt
    13561 ggacgcacat ctaaacaaaa acgagcggat aatgattctg gcgtttggac aagaagattt
    13621 tcccgttcac tgatttctcc cgaaagataa taaggcaagc cgcaatttgc aaaagaaaca
    13681 tacggtcctt tttcaaaaac aacgatttct gcatcttcca ttaatcggcg aagccgtgta
    13741 gcagcagaca ttccacctgc tacacctccg acaataacga ttttcatctt atttccctcc
    13801 tactgttcga tcaaaccatt gattcatgcc accacgtaca ttcactacat cataaccaga
    13861 tttctttaat tctttagctg cttgtttact cctcatccct gattgacaaa tcacatagac
    13921 ggtcttttct ttgtctccat catatctgtt tatactttgt aatggaacat ttttagctcc
    13981 ttttatatgc ccgccccggt attctgcagg tgttctaaca tcaagtaacg ctggattttc
    14041 caaaagcttt tcctttaatt ctgggactgt tatcgatttt attgattgaa atagcaaatt
    14101 cattttctgc acctcattta catttttata aatacctcat ggggtatatt aaacaggagc
    14161 tttattaata tgtcaaccag aatgactctt catttttttc actacttttt atatttgcat
    14221 aaaataccga taaggggtat tatctaatta taaaaataga ggagaatgtg ttatggagat
    14281 tgataataaa aatatcctga accgtttgaa acgtacagag ggacaaattc gtggtatcca
    14341 aaaaatgatc gaagacgaaa aagaatgtat ggatgtcatc actcaattaa gcgctgttcg
    14401 ttctagtatt gatcgcgtaa tgggcatgat cgttgcagat aatctgaaaa attgctttga
    14461 gaaacctgat agtaatccag aagaacaagc ggctaaacta gaacaagcga tcaagatgat
    14521 tattaaaaag taaaggaatg atttcaatga aagtcgtttt ccatattgat gaattagaaa
    14581 aatggtcaga aacagggaaa aacgtaaaaa acctgataaa agcttctcca gaaacgacga
    14641 ttgtcgtatc tgtaaatggc atcgcgatta ccggttatct agactctgcc aatgcagaat
    14701 tcttagattt gcaaggagtc gtttttcacg cttgcgccaa tgctatgcgt gctaatcata
    14761 tttcagaaag ttctttacct gaacaagtaa tcgttgtacc agcaggtgtc cttgatttag
    14821 ttgaactgca atcccaaggt tatgcttata tcaagcctta gtcagtagag gttgcgacag
    14881 aagtgatcag cttcaagaaa tttcggctta tttttcgaag aagctacttc tggaaaaccg
    14941 tgaatcaaag gttgtgaaaa cgctgtcctg catcaagtaa taagaacagc caaacaaaaa
    15001 tagcttctca tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac
    15061 cgtttaagga agaggttgtg aaatcagcgg tttgacctaa gtattagaga aaaaaacggg
    15121 aaaatagctc ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac
    15181 accgtttaag gaagagattg tgaaaaagtc gcttagtttc gagtattaag aaaaattttg
    15241 tgaaaatgga tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg
    15301 aataccgttt aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagaaacaa
    15361 acggaaaaat agctgctcat attttgccgt tttttgagct aataccgaag gtcagctgat
    15421 tgaacaccgt ttaccaagag gttgtgagcc taccatttaa ctccgaatca caagaaataa
    15481 tttcaaaaac aacttctcct gtttttggtt cggttggctt attatcgaga agtagctact
    15541 gggagtctat ttatcaaaaa aaggaatgcg acataggtca cacccctttt ttattttctt
    15601 tgaaacatct ttcggtactc gacagcatac aagacaaaag attgtaaaag accgtaagtg
    15661 atgacggcaa aaatgactct cacccacagc gttggtaatt ctgggaaaag cagcaaaagg
    15721 atcatgccaa catagatgac agcagtcgct actttgccat accacttcgc tccacttaat
    15781 ttgatatttt tagatagccc gattaatcca gctacaaaca taaagccttc ttttatcaag
    15841 aatagaccaa acaacagcca aagccacggt cgataccatg ccatagacaa aatcagaaaa
    15901 agttgtgtca atttatctgc aaacggatca agcaccttcc ctaagtctgt tacctgatta
    15961 tatctccgag caatgacccc gtctagataa tcagacaaac ctgagacaac aatgaccgct
    16021 cctgctatat aaaatgactg tctcagcaca aaataaagat aaatcggcag caaaaaaata
    16081 cggaatatcg ataaaagatt cggaatcgtt tgtatttctt tacgccagtc tgtgcttaat
    16141 ttcattttat cgccctacct cctcagcact cttttctttt tattttagct tacacgggga
    16201 ataaaaccaa tgatttcact gtttttattt ttctttacag acactgatat tatgagctaa
    16261 tttgagataa tcacttgctg ttttcatcgt ttactcttct ttcttcctgt cgtttgcgca
    16321 tttcttttac tagtacttta tgagcttttt ttgatcctcg ctctaggtca cgctgccgtt
    16381 tacgtgtttt ataatcgata aacagactgt ctaaatcgta acctgtcggg tacagatctt
    16441 ctgctgaacg caccagacga acacgctgac gaggcacgtg gattattttt ttgtctaaat
    16501 atacatcaat cgtatcttca cctatatctt cataaactaa cgcttctttt tggtattcat
    16561 tgacaaatat ccgatcacct tttgcaaaga gctgacgttc ttttttattc tccttcctat
    16621 ttgtaactgc tgtcttagga agaaattctt ttttctgtgt ccgataggct ttttccgcca
    16681 agtaacgctc tgcttgatgg atcaatttca tcgacatatc cattttatga gcaatccaca
    16741 aagcttggct ttctcctgtt tcttccaacc cgcaactgat atttaggacg aagtgcttcc
    16801 cgatcgaaag ccatagcagc cggcacaaaa tcttcatgat ctccggcgaa tttcttgatt
    16861 tctccataat gggtcgtggc aatgatcaat gccccttgct catacataga ttccatgatt
    16921 gcgatcgcta gtgcagcccc ttcatttggc tctgttccac tgccaatctc atctaaaagt
    16981 accaacgtat tcctttttat ctttttcaaa atagcagcga tgttttgcat atgaccagaa
    17041 aatgtactca acgcattttc taaattttgg tggtcaccga catcgacgaa aatctcatca
    17101 aagacagcaa gctctgtccc ttcttttgcc ggaacttgca taccgaacat cgccatcaaa
    17161 gtcaataaac cgactgtctt caacacgact gttttgcctc cggcatttgc tccggtgata
    17221 atcaagcctc gatagtcttt accgatttca acatccaatg gtaccgcatg ctcaggtaaa
    17281 aatggatgtc tgccttgctt gataatgata tgttccgatt tattgattct aggtgtgctt
    17341 ccattgattt ctcggctaaa ttttgcccga gcaaagatga tatctaacac cgtgatcgtt
    17401 tcgatcaata aatcgatcac ttcttcgttt tctgcgatag caccagtcaa tgccgctagg
    17461 acttgatatt cttcactgat ttcttcagct tttaacaact gatagtgttc attcaattta
    17521 gaaatcacag ttggttcaat aaaaaccgtc gttcttttat ttgattcatc gataatcgtt
    17581 ccatctattt tatttttata gctggctttg ataggaatcg tatagtattc gcctttttga
    17641 acaatcattg cttcttggat catttctttg tttttcggat gacgcaagaa tttcagtaat
    17701 tttgactgga tttctttttc gattagttgt aattgtttgc gtactttacg caaattacgt
    17761 gacgcgtcgt cactgacttt attatttttt attttctggt caatcaactc ttctacattt
    17821 atcaaatcag gaagatgttt gctataagca aacaacaagg gtgtctggta ttgattctta
    17881 tcaaaaaact ttgtgatcat ccgactgctt ctaagaaaat ccgcatattc gatcaaatcg
    17941 gttggctgca gaatcaaccc ttttttgact tgttctgtca gtgcatcgat cctcggcaac
    18001 cccataaatg gaacatgctg actgctttct aagatcaagc gtgcttctct tgtttcttct
    18061 tgacgatcca agacagtttg taggtttgtc gagaccgtca tatcgctgat tcgttttttg
    18121 ctatagtttc caattgctct tgcttggatt tcctttttga tccgatcaaa ttgtaattga
    18181 ctaatcattt cgttgtccat attctctcct tttcttgaag agatacctgt cccaaaataa
    18241 ataagggcct agagataaat aaaaggatag aacacagctt aaaaaagtca tgtcctatcc
    18301 ttattagaat acaaagatat tgttttcctg acaggtaccg tttcataagc acaccaaata
    18361 aactttgttt attggctatt cgacttactg attagatacc agctacactc acaaaacata
    18421 ccccattctt ctaggtctta tttattttcc acttaactat agcaagacac attttggttg
    18481 tcaaacttta gtatgtttta tagatttaca ccattaatga atagacacct accgcgataa
    18541 ttgctccgat cattggacct gcgattggta cccatgaata tgcccaatct gaagttcctt
    18601 tattagctat tggcaatacc gcatgtgcta atcgaggacc aaagtcccga gcagggttga
    18661 ttgcatatcc tgttggccct cctaatgaaa gaccgatggc taagatcaat ccacctacag
    18721 cgaatacgtt cgttccaggt gcaaattcgt tttgtccaaa agctagcaac ccaagaacta
    18781 atacaaatgt accaattaat tctgtgatca catttgctgg ataattccgt atagcaggac
    18841 ctgttgcaaa cgttcctaaa atcgcgcttt catctttcgt tgcattccaa tgtggcaaat
    18901 aagaaagcca aacaagaatg gcccctgcaa aagctcctaa aacttgcgca atgatgaaag
    18961 gaacgacaag attccaacta attgcccctg tcatcgccat agctagagag actgcaggat
    19021 tcaaatgagc tgggcccatg aatccagaaa tatagacagc cattgttaca gcgagtcccc
    19081 aaccaaatgc gatgacaatc cagccagaag cctgtgcttt acttttgttt aaattcacag
    19141 ccgcacacac accatctcca agcaaaacta ggatcagtgt cccaataaac tcccccatga
    19201 tttgagtcat atcactgttc atttatttct ccccctttag ttcccgcaga tctgattctg
    19261 caatcaatgc ttctaaacgt ttagtctgtt gcgccttctc ctcttctgtc cattcaaaat
    19321 atccagcaat tgcatcgatc acaggttgct tgatctcatc aagctgatct cgttcaaaca
    19381 acagatgatt tgtacgacga atgagataat cgcctggggc caaaaccatt tcttcttcta
    19441 aaccataacg taaccgagct gactcagcga gactcaaacc aggataaggt gccatttctt
    19501 ttgctaattc aaagatacgt cgggcattag tcccgtaaaa atcagcgata taagtagcat
    19561 cttcttcctc taaaccggct gctactcctt cttttgctaa ttctgtcact gtttcttcta
    19621 atttagttgg atcgaagttt ccacctgaaa tctgatattt tttagagtcg atttctttcg
    19681 tctctattcc gtattcttct tttaataatt ggcgtatcaa tcgcaaagct ccttctgcca
    19741 tcttacggta atcggtgatt ttcccaccag ataaagtcag caaaccatct ggttctcttt
    19801 ctaaagaact acctctggaa atcgtagaag gtgctttttc atcacggctg ttttccaaat
    19861 ggttcaacac gtcttctact tcagcacgag aaactttgtt ttccttatat tcacttactg
    19921 tatcgacaac tttattgaag ctcttgtctg aaatcgatcc attatctcca ccattgtaat
    19981 cagaaccaga attaccaatc aacagtggac gaagtcctgc ccagcttgct tcgatatcat
    20041 tcaatgtgat atttgcttct ggatagcgat gattgatcac atccaataga taatctacat
    20101 cttcttgtgt gactttcgga tccgtaaaat ctccttggta atccgtatct gtcgtaccaa
    20161 agtaagtctt gttttctctt ggaatagcaa aaaccatccg cccatcttgc tttcctgtat
    20221 cgaagtatgt gggttgcggt acaggcagtt ttttcgcatc tacaactaaa tggatccctt
    20281 tagttggacg cattttagga gagactggac gcgtaaaatt caagtttcgt actttatcta
    20341 cccaaggacc actcgtattg atcactaatt ttgctttgat ttcgatcact tcatctgtca
    20401 gcaggtcacg agctttgacg ccaacgattt gatcgccatc atataaaaag ccaaccgctt
    20461 tcattttact tactagataa gccccatctt cggcagcctt tttgatatta tcaatcacta
    20521 aacgggcatc attgttgcgg aaatctagat agacacccgc gccttttagc ccttcttttt
    20581 tcaaaaacgg ttctctttcc aatacttctt ctggtgtcag cgtataattc tcatatttgg
    20641 ttcctgtcac atttgccagt ttgtcataaa ggtccattgc tactttgacc gagaacatat
    20701 tgaaggttgt tgctccttcg ccctcataga ttggcaaaag cattggatct ggttttggga
    20761 tgtgtggggc aatactttgt acgactgcac gttcaccaac tgtgtcagct actacttcca
    20821 catcaaatgt cttcagataa cgaataccgc catgaacaag tttggtcgag cgagaggaag
    20881 tcccttctgc aaaatcctgc atttcgatca atcctgtttt gattcctgat gctgctgact
    20941 ggactgccac accggcacca gtgattccgc caccgatgat caacagatcc aattcttctt
    21001 gctgcatttt ttgaatgcta tcttgtcttg tcttgtttga aaacatatgg atttcctcct
    21061 tattcaaatg cttgggtagc ttttactgct tttttccaac cgttgtaaag tttttctcgg
    21121 cgctcttcct ccatttgaac ttcaaatagc ttgccagctt cataaaattc gcggatctcg
    21181 tctgtatctt tccaataacc gacagctaat cctgctaaaa atgctgcccc tagcgccgtt
    21241 gtttccaagt tttctgctcg ttggatcggt acattcaaga tatctgtttg gaattgcatc
    21301 agatattcat tgtttgctgc accgccatct actttcaata caggaatctt gattccagtg
    21361 tcatcttgca tcgtatcgat gatatctctc acttgataag caatcgactg taaagtagct
    21421 ttaatgatat cttcttttgt cgtaccacgt gtcaagccaa acatagcccc tcgtgctgcc
    21481 tgatcccaat aaggagcacc tagcccaacg aatgcaggaa caacataaac ctcatcttcg
    21541 cttgtagagc gtttcgctgc gtcttctgaa tcgctagctt tttgcaacat ttgaagtcca
    21601 tctctcagcc attgaatcga agaaccagcc acaaaaatac ttccttctaa agcatagtaa
    21661 acctttccat ttatgccgta accaattgtc gtcaataaat tatttttgga taattgcggt
    21721 ttttcaccgg tattcatgac aataaatgaa cctgtaccat aagtattctt gaccatgcct
    21781 ggttcgaatg ccatttgtcc gaataatgcg gcttgctggt ctcctgccat ccctgaaatt
    21841 ggtgcttcgc ttccataaaa atgataacct tgcgtataac cataaacttc tgagttagaa
    21901 gtgacttttg gtaacatcac tcgaggaata tttagtaaat ctaaaatctc ctgatcccaa
    21961 tctagctgat ggatattgaa caacatcgtc cgactggcat tcgagtaatc agtaacatgt
    22021 gcttgtccat cggtcagttt ccatactaac caagaatcga tcgttccaaa catcaattcg
    22081 cctttttcag ctcgttcttg cgcgccttct acatgatcaa gaatccagcg tatcttcgtt
    22141 gctgagaaat aggcatcgat cactaaccct gttttttcgt ggaaaaattc ttgatagcct
    22201 tcatttttta agttatctgc aattccagct gactgtctgg attgccaaac aactgcatga
    22261 tagattggac gtcctgtatc tttttcccat attactgttg tttcacgctg gttcgttatg
    22321 ccaatcccag caatctgatt tggtttgatc cctgattcga tgaacgctcc ggcaataact
    22381 gactgtacag aattccagat ttcatttgca tcatgttcca cccaactttc ttgcgggaaa
    22441 tattgcgtga actctttttg agaactgccg atgtgtcttc ctttcttgtc aaagataatt
    22501 gctcgtgagc tagttgtacc ttggtcaatc gccatgatat acgttgattc tgtcattgtg
    22561 attccctcca ttatatgcaa acgctttctt taactactct tatcatacta ctgttttaaa
    22621 aaaagaaact gtcaaaattt tattcttttt ttcttttttt gacagttttt tattatgaag
    22681 ctatttttta atcaattctt ttcttttttc agcgtctcta ttcttctttt caatcgaata
    22741 atgtcgtaag gtgacgcaaa ttctgacaga taatattcac actgtttttt gtttctctgg
    22801 caaaatgtga tcaccaaatc atattcttta ccttcttcat aacttccaat ctcaataccg
    22861 ccgattcccc tcagttctct gatcagatat tgttgaaaag caatacgata aatcggcaga
    22921 ctttctaaat cgattccaat cactactggt tttgcaatat aaaaatcgat catcaaaaga
    22981 acattggcat actggatcat caggtaacta agctcactat cttcagctct tttcctcggc
    23041 aattgctgca ccgctgtttc ctgtaatttc gccagtaact gtgttaagga atgcccgagc
    23101 attttctgct gctgttccaa aagccgatca cgctcataga cttcgatctt tccaacaaag
    23161 aaaaaccatt cattgttgat ctgggaaatt tggtagccta ctgccttttc ttctttgatt
    23221 ttcaaacgac gaggacgata atgccataac atcgtttccc gaatgtaagt atctaaaaca
    23281 gcggttggta actttttgct ccgtgtcaaa tcatactgat aaaatatttc ttcgtctact
    23341 atcgaaaaag aaacaaaaaa gctgtaaaac atcattgttt cgtatacatt cagttctgct
    23401 gctgttcgac taagatgcat cacgatgatt ggatcgattg cttgataaag ccggtccgac
    23461 tgatagagta atttcttttc tttcaaagtt gcgtacgtac ttttttcatt caatagtctt
    23521 tttttcgtaa tcccgagcca gcaagcaatc tgtgcttctg ctgatgccgt aaacgttgtt
    23581 tctaatacac ggtccaatcc tagaatgaac ggtctttttt ctggtgtatt ttgcaaaaaa
    23641 agcggtcgct gatcttccgg gatatattgg aatagttcat aataaaaata tcgtatctgt
    23701 agctcttctc cgtataattg accgtttttg atttgtaatc caaattcctc taagagctgg
    23761 ttcaattctt tgatctttcg aaaaacagaa gactcactga tattaaacgc tgtcgctaat
    23821 cgaacgatgg atacttgctg atgttctaat aaatagacga gcatcttaaa cttcaagctt
    23881 tcctgcaata aaaacaatag aattttttcc aaacttacat cttcgtccaa cacaagcagc
    23941 gcctgatact catttcgctg tacttctact tttttttcca tcattcggcc aatcaattca
    24001 atatcttcca aatattgatc aaacgaggct tttgacagtt ggacatgctc tctcaaacca
    24061 ttgatagagg ctgttccccc ttgcagaaca aggtttcgca aaatcaggat ctgtaactgc
    24121 tcttttcttt ctaataatgc ttcaatcttc ataggcagta ttcgccacct ttgaccacac
    24181 catatctggc acacggtatt ctggctggaa aaatagctca tgttcttcta actgttcaaa
    24241 cgtccatcct tcttctactg caattgtcag ttggtcaaga aggtggaaca tctctttttt
    24301 gctttggagc tgtgctccaa gaatcttttt ttcagaatca aatagaaatt tgagtttaac
    24361 tttgctttga tttattgctg taagcttgta gtctacgtat cctgtttcaa ttttttgggg
    24421 ataaaaaatg ctctcttctt ctgtcaaacc tacgcttcct aagaaatagc caaaccactg
    24481 attgccgact ggacgatagg ttccctgatc ctttgtctgt gagccactaa ttgtcttgct
    24541 gacatttcgt gctgtacgga cagcgttatt tactagagaa acatacattt tttcatttgt
    24601 tggacgaaaa gttacttgga tcgcatcgcc aatcgcataa acgtcttttt gagacgtttg
    24661 caagtagtca tctacccaga tcgttccatc atcattcaat gttaattgtt cttcccacat
    24721 ctgattgtcg ggacgagaat gattagccag caaaacaaga tcatagttct cctttctttt
    24781 ttccgtctct acaatagcgg tttcattttc ggtcaaagac acaacttgtt cttctaaaaa
    24841 aagtgaaagc ccttgatttt tcatttcctt tactaacggt tctgtcattt caggatctag
    24901 ataacgaaaa agaattgact ttcggctttc gtaaagatgg atttgttttt ttcttgatgc
    24961 caacccttca gctatttcga ttcctgcttg tcctgcacca ataattgcaa ttttctttgc
    25021 attcatgatc ttttgctgaa gagccgttac gttttgtatc tttttaactg ggtgaataag
    25081 cgttgattct gcagaaatat ttcgaaactt ttgatttgaa ccagtcgcta gaatcaaacg
    25141 atcaaaatcc aatttttttc ctcctgctaa aacgactttt ttttctttca atcctattac
    25201 tgtcttttct gtgtaaacat ggattcgata gcggtcagtc agttcttctt tcgtgatcca
    25261 agaaagttgt ttttcactgg taacctttcc ttttaatatc aaattgaacc cgctgggaat
    25321 ccatcctaac ttcgattgct tttcaatcaa atatatttca cttgttggca tcaattggcg
    25381 aagataaata gccgcatgaa tccctgcaaa cgacccgccg acaattacaa tgttcatctg
    25441 cattcctctt tcttataagg tgttctactg ctaacttctc aatcagaaaa cacagtattc
    25501 ataactcgct ttcaacctta tgatacatag cgatgcagca gaatcaaccc tctccatcat
    25561 accgtgttct aggtctgctt ctcaataatg tactagtgga cctaattgaa gagtatcatt
    25621 tctgaagaga tgtttcaaaa aatgtactct tataaaagaa aaaaactcgc cttttacgta
    25681 cctctgtcca aataggaaac agaaaagaac gaaaagacga gttttagcgt gtgtaatgta
    25741 atagttagaa tagacacatc atttattttt aattctttaa tgcttcaaca actgcttcgc
    25801 ctaattgatg agcagattga ggattttgcc ctgtaagaag ccgcccatca atttgaacca
    25861 cttctgaaaa agctgctcca gactgatagt ttgctccttt ttctttcaaa gcatcttctg
    25921 ctaagaatgg tacttcattc gttgtaccat ttgcttcctc ttcttcatta ctgaacccag
    25981 tcactgtacg tccagctaaa atagattttc cagactcatc tgtaactggc aacaatccta
    26041 caacaccgtg acaaacagct gagaccagcc cttcatttcg atagatttgt gaagcgactt
    26101 tcccaagatc tattgcttct ggaaaatccc acattgttcc gtggccacca gcataataaa
    26161 ccgctgcata atcatttgca tccacatcat caggacgtaa ggtatttccc aaggcccgat
    26221 ttctgaaatc ttcatcttca taataggccc aatcgatttc atccatattc aaaacacttt
    26281 gcggttctaa aggtacatat ccgcctttag gactgacaaa atctgcatcg atcccatttt
    26341 ttactaatac atcataaaaa tgagtcagtt cacttaacca caaacctgta ggacgctcga
    26401 tcttttcgta cttttctaca tttgttaata cgatcaatac tttcattttc ccatcctctt
    26461 tctataaaaa ttgcgttatt gataacgtgc tttcaagaaa ttatataatg ggcttggcaa
    26521 ataaagctct ttatatgctt cttcaaaagg tttcgttaca aattcatcct cacggttttc
    26581 caataatttc tctgcccagt caggatcgac gatcatttgc tgtccaattg ctgcaagttc
    26641 tgcatatttc aatacctgct ctacatcttc gcgattgcgg atcccaccga caccaactaa
    26701 agggatcttt ccttgaatcg tgttatggac cacttcaaga atcgatttat cgttgtattt
    26761 atcagaacga gctattcgat catacatatt taatgaaaca tgcagataat ctagttttga
    26821 ctcacgtaat cgttcaagaa gccagatcgt gtcttcaaaa cggatacctg gtgtttcata
    26881 ttcttctggt gagaaacgat accctacgat gaatggtttt ttagcatatt gttcaaccgc
    26941 tgagaaaacc gttgttaata attcttcaat aaaacgataa cgattttcca agctaccgcc
    27001 ccattgatcc tctcgtctat tcgaatgcgg agagaaaaat tgttggatca aatacgtatt
    27061 tgctccatgc aactcgattc catcaaatcc tgattcaatc gctctacgtg tggctttgcc
    27121 aaatgcttgg attgtttcaa cgatttcttc ttcactcatt gctcgtggtg tttccgcatc
    27181 aggacgtttt gctgcaactg cacttgcaga tacaggctgt tctccagata aagttgctcg
    27241 acttgtcatt cgtccaccgt ggaaaatctg aataatcgct tttgcgcctt ctccttggat
    27301 tgctttcgct agctcactta atcgaggaat catttcatca tgagcgatgc tgagttcacc
    27361 tggccagcct tttccgatat cttggacatt tgcagcacca gtaataacag caccaagacc
    27421 tttagaacgt tgtttataat aagtgatctc atcttcggtg atcactccat tgaaaaagct
    27481 gagttgtgtc gtcataggcg acagcatcaa tcggttcttc aattgaactc ctgaaggtaa
    27541 agtaattgat tgatcaaatt gtgacattgt cattcctccc ataattcgct ctgattaacc
    27601 tatcgagaat catctatcat taaaccactc gattagttgt acatgcaact aatttgctta
    27661 aaaaatttta ttttttttgt aacttatctg ttgcatcatt cattgtctgg gctaattctt
    27721 tacttgcttc atttcccaaa actgctttgt atgactgatg aagttcttcc cagctaccat
    27781 cgacttcctt agcaaattgg cgtccttgtt ctgtaagata aactaatgac aagcgacctt
    27841 cgctaactgt tttgacgtat cctttatatt ctaatttttc aacaaaacga gcaatcgttg
    27901 atggggcgga atagagcatt tgtgcaatat ctttttgtgg tattccatct ttttctttta
    27961 atatcaataa aataaaacca taagttggtg ccagacctgt ccttctaaac gcttcatcag
    28021 ctaatttatt caacatgcga tctagctttt tcacgctaaa gaaaagacat tcatctaacg
    28081 ctttttcaat tggcttttcc atttcatccc ctccattggc gtacatatca tagtatgatt
    28141 tttatttttt gtcaaaaaac acggaataat gtccgcctcc tctgtctaga tttgaaaaaa
    28201 agaagtagcc atcttcaaag aatttcggct tgttttcgac aaaactcctt ctggaacacc
    28261 gtgaatcaga ggttgtgaaa aagtcgttta gttttgagta tgaagaaaaa ttttgtgaaa
    28321 atggctttcc acatttttgc ataaatttgg cttaataccg aaaaactggc ttttgaacac
    28381 cgtttatatc agaggttgtg aaaaagccgt cctgcatcaa gtaataagaa cagccaaaca
    28441 aaaatagttc ctcatatttt gtcgtttttt gagctaatgc cgatggtcag ctgattgtac
    28501 accgtttatt gagaggtcgt gagcctgccg ttgaactccg agtcacaagg agcaatttca
    28561 aaaaacagct tctcatgttt tatgactatg gtgacttgtg atcgaggagt tggcaggaga
    28621 atactgttta ttcgtaaaga aggggctgtg acaagacttt tgtcacagtc ccttatttcc
    28681 ttttattata ggatttcgcc atttgattgg atgacttgtc tgtaccaatc aaatgatttt
    28741 ttctttaacc gtttctttgt gccattccct tcgtcatctt gatcaacata gatatatcca
    28801 taacgttttg acatttgtga agtagaagcg ctgacgatat caatgcagcc ccacgacgta
    28861 taaccaaata aatctactcc atctttgata gcttccttca tctgctcaat atgctgcttc
    28921 aaatagtcaa tgcggtaatc gtcttgaacg gttccatctt cttctacttt gtctatagct
    28981 ccgagtccgt tttcagctat gaacagtggt ttttgatacc tatcatataa ttgattcaaa
    29041 gcaattctca aacccttagg atcaatctgc cagccccatt cacttgatgg aagatacgga
    29101 tttttaattc ctccagttat taagtttcct tggacccctt cccaattttc tggatgagca
    29161 ctgactgcac tagacatgta gtagctaaaa gaaacaaaat caacagggta ggctgctaag
    29221 atttcttcat cacctacttc tatttttaag ttgacacctt tttcttcaaa cattcgttgc
    29281 gtatacgctg gataatatcc tcttgcttga acatcactaa agaacaaaga agttctttgc
    29341 tgctcaattg ttttttgaat atcatccgga tcacaagaat acggaacaag aagctgatag
    29401 ctgatcatac aaccgacttg tgaacctttg ataatttcat gacaagcttt tgtagctaaa
    29461 gcacttgcta taaactgatg gtgtgcacct tggtatttcg cttgttccaa atggggatgg
    29521 ttttcttcaa ttactcctac gctaacaaaa gggtgatgtt ttacacagtt gatctcattg
    29581 aaagtcatcc aatattttac tttattttta tagcgtttga atactgtttc agcgaaacga
    29641 acgtaaaact gaataagctt tcgattaggc catccaccat attctgtaac caaatataac
    29701 ggcatttcat aatgggaaag agaaacgact ggctcaatcc catattttag acattcgtca
    29761 aacacttgat cataaaaaaa taatcccgct tcattgggtg tttcttcatc accatgagga
    29821 aaaattcttg tccatgcgat agacatccga tagcatttaa aacccatttc agcaaataaa
    29881 cggatgtctt ctttaaagtg atgatagaaa tcatttccgt gtcttttagg ataataatac
    29941 ttgctgttgg gatcctgcgc cgcttttact tgctgatgcg tcatcatatg ccattgatct
    30001 gtccattttt ctttaggtaa atcgctgtcg aatgtataca catcagacac agataatcct
    30061 ttttcatcta catcccatgc accttcacat tgattggccg ctgtcgctcc gccccataaa
    30121 aatccttctg gaaatttttt catatcgatc cccctaaact tgctagtttt cttgtttgat
    30181 tatttttctt atgactagta atgatatttt tgaatctact actatttgta acaataacca
    30241 ttgtggtcgg atcatatccc tctttgatta attcttgcaa atctacttcc atcaataaat
    30301 cgcctttacg tacttttttt ccatcagata ctgcactttg aaagtatttg ccatttaaat
    30361 tcactgtatc aataccgata tggatcagta tctctgctcc ttcttcactg actaccccaa
    30421 ttgcatgttt cgttggaaaa actgttgaaa cttccccgtt tacagaactg tagatttttc
    30481 cgtccgttgg aatgatcgca aacccttctc ctaaagatcc actagcaaat gttggatcgt
    30541 ttacttcaga taaatcaatt atttcacctg ctgcaggagt acttaacact atatcctttg
    30601 aggattcttc ttcgatttca tccttgtagc cgaaaagaaa agttagcata caggaactga
    30661 tcatcgctaa gaaataacta gcaactagcc aaacaaatcc ttcaccaata taaatcggga
    30721 aagacaaaat acttcttgta gcaactgcca aagcaccggc tcctgcggca ccagctactc
    30781 caccaaatat agctccacat atacaagcaa tgtaaaatgg tcgtttatat ttaagagtca
    30841 caccataaac agcaggttca gtgattccaa ataatgctgt gataaatgca gataaagata
    30901 aactttttac tttcttattt ttcgttttca aaaatacccc aagtactgct cctgcttgcg
    30961 cagctacggc agtcatacat gctggaccta gcgtatcacg accgtagaaa gaaagattgt
    31021 tggtcattac tggtacaagt ccccaatgta acccaaaaat cactaacact tgccaaaatc
    31081 cgccgataac agcaccagat aaaacagggc taaagttata aacagctaaa tatccagctg
    31141 caatcagctg acttgcataa tctgcaattg gacctacaac taataaaata attgggacca
    31201 tcacgatgat acaaatgaat ggtgtcaata aatttcgaat actttcgtgc aagcttttgc
    31261 gaatcttagg ctcaatataa gaaagaaccc atacagctaa aattgctgga ataaccgtac
    31321 ttgtatacct tgctagaatc acgggcatcc ctagaaatcg caaggttatg ctatcactat
    31381 atgcactgac aatcgtagga taaacgagag ctgctgcaat aaccatagcg atgaaacgat
    31441 ctgtattgaa cttttttgca gcagtatatg ccaaaaatat aggcaagaaa tagaaaaatg
    31501 catcagctgc tgcattcaaa atgatataag ttcctgattc agtagttaat aaattcaaac
    31561 tcgtacataa ggcgagtact cctttgatca aaccacttcc tgccaagacg cctaaagtcg
    31621 gggcaaaaac agcggcgatc atgtctataa aagagtttaa aatgcctttt ttctcagttc
    31681 ctctctttcc actagatgca tcatcttcta gtttcatttg tttggataat acgtcataca
    31741 cttcatttac tgcatttcct actacgactt gaaacattcc tccagcttcg actacagtga
    31801 tcacaccttc tagttgctct accttctcct tatctgcctt cttattatct tttagggtaa
    31861 agcgtaacct tgttgcacaa tggtaaacat tgctgacatt ttcttcgcct ccgacaaatc
    31921 ggacaatatc tttcgctaat tgtgaatagt ccatttttac ttcccccttg ttaattaatg
    31981 ccgtagcaat ccttcttaca agataagtat agttcttaga aaacggtttc tccattcaat
    32041 tagtacccct tctaatagcg aacgaaactg tacaatagtg tgtatggttt acttagccga
    32101 gcaaatcact cactgcttga aagaaaacaa gtatatcgtt tctcttatag tcaaaggaga
    32161 caaaaaaaac acgcttgatc ttcctttgct gatgtataag tggtatctca agctgatact
    32221 ctgtgatttt tgtttctact tggcttttga taagacagca caacaaagtc tcggcattta
    32281 acggaagcat aactaggtca gaactaggag agattagttg ctgaatggaa tctatctttt
    32341 tatggatttt tatttgattt tcttctttgt agtaatgatc aagcagtttt gttttctttt
    32401 tttcttcaac tatggtcagc ttttcacgca aaatctgata aatctcccaa gattcaaact
    32461 catctagaac actaggtaga taaatcaaat catcccactc aaaaataagc tcttgctcag
    32521 tagtcaaaat tgcatcatat tccgttattt tgtttgattg atttttgaaa agatacactg
    32581 gttctatccg gcattctttg atccacatgt tcatactttg ttgaatctgt ttttttagtg
    32641 tattcaaaat actaattggc tggttactaa caatcagtat ctccccttgt tttcgaaaag
    32701 gattcaacgc ttcggcaaga tacaaaacaa aataagcgct ttcagctaaa ttgggacgta
    32761 attgaaaatg tattgggaag aaacgccgaa ttaaataaat ttctaaagga taacgggaga
    32821 tgatcttttg tacaaaatga ttcatggtat tatgtccggc atccatcctc gttttcattt
    32881 gtttgatatg ggttagcaaa aattctgttt catggaacaa taacgaaaca ggaagatcta
    32941 aaaaacgaat aatcgtttgc tcaaatgctc ttagattctt ctctatttct ttgttttttt
    33001 catcattaat catcaaataa tttaactcta atagtcgatt ttcaattgct tgtttttctt
    33061 gattggaaaa agaatagggt agttctgatg ataacttttt tgtgagggtc tctaccatcg
    33121 gaataaataa tgtatacctg tttgtttttt ctaaaagttc ttctcttcga agaatggtca
    33181 aaacgagata ccgagaaaat cgtatgaagt cctctcctga aacaatataa ttatatgata
    33241 taagaacctc ttttaatgtc ttttggacag tcggcatgat attggaaaaa attgtactga
    33301 tttgttgagg aaaccttgcg tgttggatca ccgtttctgt tccaacaaga gataagaaaa
    33361 ttctttttga attttcttca gcaatgattt ttagtccttt tgtcgacgaa acttccagtt
    33421 ctaatttagg attgcgctcg atccaacgca aaatcgtttt tatttgtaat gatacggctg
    33481 tttttgaaag aaagaaaatg tctgctatct tttgcatact gacataccct ttttgaaaca
    33541 ataagtacgt cacaatagtt gaagctcgga aatccatgct ggaatagatt ttatgtttcg
    33601 tcacctcttg tatgatttgc tgtttagttt cagattcaat tgattctaaa aaataacctg
    33661 aacgtttatt tgactggata atgattttct tctcgtagat agcaagcata tttttgattt
    33721 cagtttggat cgttttcttg ttggtaccta aagcttcagc taattcttcg cttgttatcc
    33781 aatgattctt atttcttaat actacaagaa tttggagttg tcgtttattt aagtccattt
    33841 gcttacacct cctctttgtt ataaacatac aggaaaaacc tctcaaatga caatagtcac
    33901 ttgcagaggt ttaaaaatca tttgaagaaa gatctatatt caaggttttt accattagac
    33961 tggataattt gtttataata ttcaaaacta tcttttttca atctcctaaa gcttccgctc
    34021 ccatcatttt gtctatccac ataaataaag ccatatcgct tcctcatttc ccctgttcct
    34081 gccgatacga tatcgattgg tccccaccat aagtaaccaa tgatttggca accatctttt
    34141 attgcctcag caatttcctg aagatgtatt tttagatact cacaacgttt tggatcgtgg
    34201 attcgattca attcatctgg tgcttcatct agtccaatgc cattttcaac tatgaataat
    34261 ggtaattcat aacggtctgt caattcattc atgacataac gaaaccctag aggatcaatt
    34321 ggccaactcc aaggttcggg agatttttcc ttcaaaaagg gattatcgaa accatttgct
    34381 ccgccagtat ctacgcgcat ttctgcttct tttttataga cagcgctacg ataataacta
    34441 aatgcaatat aatctgccgt gttagcttgc aagcactgtt cgtctccatc taacattact
    34501 ggtgcacagt cttcttcctt ccatgtcctg taaatataag ctggataatg ccctcggcac
    34561 atgacatcgg agaaaaacca tgaattgcgt ttaaattgca gtgaaccaaa tacattctct
    34621 ggatcacagt catatgcata agtcgctaat gcagaaaagc tacacataat acccatctta
    34681 gcatttggat cgattttctt taataattga gtagcacggg cgttcgctag aaacatatga
    34741 tgacaggctt gataaatcac tttttttgtt agtgtagcaa tgggttcaag tttatctcta
    34801 gcagggaatg taaccaatcc agcagctgca taaggcatac gaaaagcatt attgatctca
    34861 ttaaaggtca tccaatattt cactttccct tggtagcgtt caaagacggt ctgcgcataa
    34921 aattcaaaaa agtcgattaa ttttcgattt tgccaccccc catactctcc taccaatgct
    34981 aagggggttt cataatgact aagagtaatt actggctcga tatcatatcg atttaatgta
    35041 ttgattagtc tgtcataaaa tacgagacca gcctcatttg gcttctgttc gtctcctctt
    35101 ggaaatattc gtgcccatga gatgcttgtt cgaaaagctt ttaaacctaa ctccttcagt
    35161 aaacgaatat cctcttcaaa tcgatgataa aaatcaatcg cttcatgaga aagataatgg
    35221 agtgattcgt ctaaagcaat ctcccaaatc tttttttctt cattccactg aatactagga
    35281 tgctggttca tgatcccgat aagcgtatct gtcacattag gtaatttgcc gtcttccaac
    35341 catgcacctt cacattgatt agcagctact gctccgcccc ataaaaaatt ttctggaaat
    35401 atttcctgat ccataactat ctctcctcgc tatcaacaat ttcttacttg aagtatagct
    35461 cgattcatca aaacaagata ttctaactat ttcggcagaa gagaagaaaa aaattgaatg
    35521 ctactcttca tttttaatat ttatatataa caaatacata agacgatccc cgaaagaaaa
    35581 cactcgttaa ccatctaagc aaacgattta ttttacttcc aacacaaatg cttcataagg
    35641 tcgtaaatca actttgccgt ctggtaactg tttcagagga taatttgaca caataaccct
    35701 taaagcttca cgtggaatag tgaacgtctg cttttcactg gacatattac aaataacgag
    35761 ccattgctgg tcttcatata tgcgagaata ggcaaagaca tgctcaggcg tcttttccac
    35821 taattcatag tctccccaga cgatgatgtc atgttttcta cgcaaatcga tcaatttctt
    35881 gtacatataa aaaacagaat cttgatctgc taacgcttct tctgcattga tttctttata
    35941 atttggattg actcgaagcc atggaattcc agtagtaaac ccagcatgtt cacgggcgtt
    36001 ccattgcata ggcgtcctag cattgtctct tcctttcgcc ttgattgatt ccaagatttc
    36061 ctcttttgta aatccagaag aaatcctttc gttatacata ttgattgtct caatatcttt
    36121 tgcttccgcg atatcatcga ttgggcaatt cgtcatgcct aactcttctc cttgatagat
    36181 ataaggggtg cctttcatca tatggagcaa gatagcaaac atcttggcac tttcttttcg
    36241 atacacatcg tcatttcccc aacgagaaac aattcgcgga agatcgtgat tattccaaaa
    36301 taaactattc catccttcat cacctaaaga tgtttgccat ttggataata cttttttcag
    36361 ttcagagata ctcaagggtt tcaaatccca tttgtctttg ccttcttgct gatctaatcc
    36421 tatgtgttcg aattggaaga ccatggataa ttcatttctt ttaggattgg aataaagttt
    36481 agcgatttcg gtagttgctc cccatgtttc gccaacagtc atcagatttt tgtcaccaaa
    36541 agttgcttga ttcatttcct gaagatactc atgcagttta ggtccattac ttgtgatttc
    36601 tttatccggt tctttgccaa tcatatcgat cacgtccata cgaaagcccc caataccttt
    36661 atcgatccag aaattcatca tttgataaat ctcttggcga acctgtttat ttttccaatt
    36721 caaatcaggt tgacgcttgc tatacaagtg cagaaaatat tgccccgttt tttcatccaa
    36781 ctgccaagca gaaccactga atattgagcg caatctatta ggctcttttc cattgaccgg
    36841 atcacgccaa atataatagt cccgataagg attttcttta tttttacggg cctcaatgaa
    36901 ccacggatgt tcatcagaag tatgattcac caccagatcc atgatgatac ggatatttct
    36961 tttctttgct tcttcaatca gttcttccat ttcttccatc gtaccgaatt ctgccatgat
    37021 tgcttgataa ttactgatat catacccatt gtcatcattc ggagactcgt atactggaga
    37081 aagccaaatt gcatcaatac ctaaatacgc cagataatcc aacctggaaa taatcccccg
    37141 caaatctcca ataccatctt gatttgaatc ttgaaaactt cttggataga tttgataaac
    37201 aactgaatgg tgccaccatt tttgttccat gattttcctc ctataaatgg atgtttctat
    37261 tttttgctta atcatttatt ttagtctctc tcactaaaaa ttgtaacgct ttcaaatagc
    37321 tattgcacct tgttatcggt aacagaataa aacaaaaaaa cagctgagga aattccctca
    37381 actgtttttt gaaaggattg atttatgcag ggaagaatgc tgatttcaca acttctttat
    37441 aaacggtgtt cactcagctg tcccttggta ttagctcaaa aaacggcaaa atataagaaa
    37501 ctattttttc gtttttttct ctaatactca ggccagaacg ctgatttcac aacctcttta
    37561 tttcacattc aatatccaca tgaatcccac aaatacaaag aacagaccat acatgattgg
    37621 agatacttct tttcctcttt tagctgctaa catggtaatt ggatagaaga taaaacctaa
    37681 tgcaatccca tctgaaatac tataagtcaa aggcatgccg atcaagatca agaatgaagg
    37741 gatcgcaatc tctaagtttc cccattcgat ttgtcgcaaa gattgtgcca tcaatactcc
    37801 taccataatc aatgctggtg cagttacttg tgaagtaaca actgatagta atggagaaaa
    37861 gaacaagcct aacaagaaga aaatccctgt agtaatagct gtgatacctg aacgtcctcc
    37921 aacggcgata ccagctgatg attctacaaa tgcaccaaca ggagaagtac caaataagga
    37981 acccgcaagc atagctgttg aatcagaagc taaagctttc cctacacgag gcatcttgtt
    38041 gtctttcatg aaacctgctt ggtttgctaa tccaactaaa gttcctgctg tatcaaagaa
    38101 agtcacaagc aagaatgtca gcactacgac ccacatttga agagaattga tgtcccctac
    38161 atgttttaat gcaactaaaa atgttggttt caaacttggt gctgcggcaa caatttcaga
    38221 aggcattgga atcaaacctg tgaccagacc taaaatcgtt gtagctgcca tcccgatgaa
    38281 gatgccacct ggtacacgcc gaacaagcaa gatagcagtt acgactaatc caaaaatcgt
    38341 caaccaagta gaaccaacgt tgagtgatcc taatcctact aatgtagatt cattcgaaac
    38401 gatgatccca ccttcgctca gaccaaggaa agcgataaat agaccgatac cgccagaaat
    38461 cgcatatttc aaatctgctg ggatcgcatc aatgatcatt tcccgcagct tgaagattgt
    38521 gatcaaaata aaaatcaaag aagcaacgaa tacgccggct aatgctgttt cccatggaat
    38581 ccccattcct aaacaaacag aataagcaaa aaaagcattg atcccaagag caggtgccgt
    38641 tccaattgga taacgggcta atacccccat taaaacacag ccgatcgcac tggctaatgc
    38701 agtcgcagta aacactgctc cttcatccat tccagaagca cctaatacag ttggatttac
    38761 aaataagata taagccattg agataaatgt tgtaaatcct gccagtacct cacgttttac
    38821 cgtggtgttc aatttttcta tttcgaagta ggaaagtatt ttttccttca tcttccatcc
    38881 ccctaaatcc gaacattata aataaagtcc gttaaaattt cgatttatta ataaaacaac
    38941 gtgttttatc atatactaaa acaaaacata agtaaacaaa aaattcggat tttaagcaaa
    39001 atccgaacgt tccatctgat taaatccctt tatctcaaag ttcatgaaca ttcactttgg
    39061 attacaagaa tttctttatt gtgttaataa agtttcttca ttctagtctc aaaaatcaat
    39121 agtgtgattt gattttacca tttcgtttct gttcttcttt gatgaattct tttgtatcga
    39181 caggattcag attatttagt ccgccaaaac ctgtatcgac catttttccc cagccttttg
    39241 tcttcttttt tcctgatttg agattctttg ctcgaagctt ctcactatgt tttgctcgcc
    39301 gatacttcaa ataaccttct aatcttccca ttagatccac tgtttttcct cctttttatt
    39361 caatcagacg actcagcttt tcctataaca aaataattgc cttcagggtc agaaaaattg
    39421 aaagtcaaga tgccattgtt atctgtgatt tctcctggtt cttccatgtt ctcgtagata
    39481 gtttcaaatt catccgtaaa aaatactaaa gaaggcggtg gtcctaatac ctctggtgaa
    39541 aacttctgca caaatacttt tgggaatacg cctaattcta attcttttga gatgctgagt
    39601 acaatactct taaattcttc tggcaattcg attgtttcag aaatttctgc accaattttt
    39661 tctacaaaga atcggcaaat catctctacg tcattgacat aaagcatcac acgtgttttt
    39721 tgtatcatca tttgaccctt ctttctattt gattttcttt cctgtctata aactgattcc
    39781 attatatcac gaaagcgcaa acaccttgtg tttgatacta ttcaagaaaa ataaagcaat
    39841 agtttctagg attgctttcc tccacaaact ttttttacaa aaaaaaaacg gcaatgaatg
    39901 ccgctcttct tatttcgatt cttttataat tctgcttctg attcatcttt ggttagtgtg
    39961 tgtctaacac tagttacgcc aaatgtttga tcgatttttt ccttcaacgc ttcgattgcc
    40021 tgtgcgccac gtgccgcttg ttcagcattg atggattcaa tgaccagcac cgctgcttgt
    40081 gtttcttccg tcagcatcgt tctttgggct tcacgccagt tgagacagcg acagatcgct
    40141 ccttgttcat catagtagat gatttcttcc ggaagtgccg gagcatcgga atctgcacct
    40201 aaaggcagga atgattcgcc accttgggct tttcctaaat gcagatttcc tgcgatcttt
    40261 tcgatatctt ctccgccgca aggtacgcca aaagacaagg aaatactatt atagatatct
    40321 acaagcggat tgattgggaa aaattcccgt tcttgatttg cacgtttcag taaagcttca
    40381 atagaagaac gtgcaccttt tttagtcttg aatgtggtaa atgcctgacg ccactgagca
    40441 atgacttcgt tttggctgaa tgtttcttct gtaaggtaat ttcttgcttc ttttgctgcc
    40501 tcattcaata attgatgata cgtttcttca ctttcttttg ttacgtggtt atcgatacca
    40561 tttacggata agatttcgat ggttgcttca ggaaatactt cccagaaatt ggtatccact
    40621 attacttttt tcatctgttc acacctcttg attagaataa ttgcttgatg aatagatagt
    40681 ctgtttgggg atcatctccc atataaaaaa catgttcgct gtatttgata aatccttttt
    40741 tacgataaaa agcgagcgca acatcgttgt gttcccaaac accgagccaa atggctgttt
    40801 tttgcttttc ttttgctttt tcaatagctg tatctagtaa aaatgtaccg ataccttgat
    40861 gtttaaattt ttttcgtaca tagattcgct cgatttctaa aaaatgatca gccatttcct
    40921 cagattgact cgttcctgta tttagtttca ggtaacccgc aggctcttga tcgatactca
    40981 ctaggaaaaa atcggtttct ttatctttta gctcttctgt aagtttttct agtgcataag
    41041 cttgtgtcaa gtaatcagct aaatgctccg gtgaattatc ttttccaaat gtatctgtaa
    41101 atgtttcgat actaatttgt tgtagtaagt ctacatctga aggcgtcatt tttcgaattt
    41161 cgtatttatt cacggcttct tcctttcaat agatcctttt attgcctttt ttgacaaaat
    41221 tccaatcttc gctaacattc ttgcatactt tatttaaaag atattccaat tgttttgctt
    41281 cttcgtcaga aagaccattt aatgcgactg cattggagta gttgttttct cgaatgatga
    41341 aaggatagat ttctgctcct tttttagtcg gatagagttt cttgattttt ttattttctt
    41401 tatcttccaa acgttcgatc atcccattgg attctaattt cttgattgct cgggcagtcg
    41461 ttgtacgatc tactttgatc atttctgcta gtttttcttg gatgattcca ggattttcgc
    41521 aaatacgtac taaataaaga tactgtcctc ttgttaaatc gacttctttg aattcgatat
    41581 tgctaataga atctagcgct cgggcaatca ttccgatgtc tcgaaggatt tcagccattt
    41641 catcccacct ttattttgtt tgtaagacta gttcacctct ttttgttgca aatgcaacta
    41701 ttttcaataa aaaaatcaag ttctttttta ataactagta aagtatattc ttttcttctt
    41761 ttacgaaaaa gctcaatcac aatagatctg gtttttgttt tctaaaataa gtaactgttt
    41821 cttcgttgtt cgcttttctg atagctttgg caactcttct atactaaaaa atcccatgtt
    41881 ggaagtttca ttattctcaa taaacttggc ctcttcaccg tggatcgcac aagcaaaaac
    41941 aagtttataa tactgaaaaa gctgtggaat atctttttgt ttattcgtat caaaaactgc
    42001 tcgcaactga gtagtttcta ctgttaatcc tgtttcttca tagacttctt tacgcacatt
    42061 ttcttcagga gacaatccta tttcagcaaa tccaccagga agtgaccatt ctttcgtccg
    42121 tttatcttcg attagtagga ccttgccatc ttttttgata taggcacgaa catctacttt
    42181 tggtgttgga tgtccttctc caatcgttgt gagcgctttt atttcttcga aagtttcttt
    42241 tcctatttca ctgatcagtt ccaatgaaat cgtccggatc tcctcaaaac gctctttatc
    42301 aaatacatct tttccataat atagaccagc ttgagaaagt gcgagtagtc ttttgtattg
    42361 agccaacttc ttgttcattc tcttcccttc ttttttagca aatgtatgac tatgtaatca
    42421 agtatagaag actggtttaa ttacggcaaa taaatataat gaaatctgca ataaataaaa
    42481 gaatgttaaa aaactcgaga acaaaagaca ttcgacttct ctggggctgt gaataaatgg
    42541 cgttcaaaag cttgcatctg cggtaataag ccccaccaaa cgaaaaatat gacgagctat
    42601 tcttgtctgg ctgttcttat taattgaggc aggacagctt tttcacaacc tccccactaa
    42661 acggtgttct cctaccaact cctcggtcac aagtcacaat attcatcaaa catgagaagc
    42721 tgtttttttg aaattgctcc ttgtgactcg gagctgaacg acaggctcac gacctctcgg
    42781 taaacagcgt tcaaaagcca atttttcgat attaagccat ttctttgtta cttattgtca
    42841 ttgatttctt tttctaattt atccaatagt ggagtgtaat ccacttgagt atagtctgtt
    42901 acatcaaatt catatagtgt tcctaactgg aatttgtcat attttcggtc ggcgatgatc
    42961 tttttgaatg cttctttcgt aatatgattg gtccctttcg ttcgatcttc caatacgtca
    43021 ccatagtgat aatgatccat gatatagctc aaatgacgat ctgattcacg atcacgtttg
    43081 taccgacgtt gccataacac ttcaaagtct gctgttaggc gaatcgtgat cacctgatat
    43141 ccgtatctat ctgctaattc ttggagtcgt gctttttgct tatcactaaa aggatactcg
    43201 gacacaatca ctttctttcc tgcttccata tacaaatcaa gtgctttgta atagaaagga
    43261 taaactttcg tcctttcttg ttccgcccgt tcttccaaat tgttaaaccc gatggattct
    43321 gcatagtatt ccttgatttc atcgagcgtg atggcataca tatctggaaa tcgttcccgt
    43381 agtttattca taagatatgt ttttcctgta ccaggactac cagccagaag aatgaaatac
    43441 tttttcatct catttatttc ctaagttaat tggactttcc aagttcataa acagtccaat
    43501 cttatgcttg acaatttctt ttactgcttc atttgctgga atcacattat ggcgaagaga
    43561 cttgttgatt tctgtttcac taaaggtttc tttagctact ttcgtccagt tgactaaaag
    43621 ctccgttcca acattgaatt tgcggatccc gttattgatc aattcaggat aatcttcttc
    43681 tttcacacct gttcctccat ggataactag ggggacatca actactgcat cgatttcttt
    43741 cagcaaggga atgtttactt ctgtttttga tttgaattgt ccatgattcg taccgatagc
    43801 aatagctaat gcatccacgc ctgtagcttc tacaaatttc actgcgtctt ccggtcttgt
    43861 atataccttg tcattttcag cgacatggat tccttcttct gtaccgccga ttgttccaag
    43921 ttctccttct acggaaacac cgtgcgcatg ggcatattct actactgctt ttgtcttcag
    43981 gatattttct ttgaaaggca gatgggaccc atcatacatg acagaagtat atccgctgtc
    44041 gattgcttct ttgatatcat caaagtctcg ggcgtggtct aagtgcaaga ctgcatcaac
    44101 catttcttct tctgcaatag ctgtcattac attgactaac acatgcatgc cgatatattt
    44161 agcggtatcg acacttgttt gaataatgat cggcgaaccc atttcttttg ctgcgcctag
    44221 catagcagga agcatttcta ggttatgcgt attaaaagct ccaactgtaa aattcaactc
    44281 ttctgctgtt tttgttactt ctttcaatgt tgtatacatc ttttattgcc accttatctt
    44341 tttatttgtt tcctttgatc gttacttgtt ttgcaatttg tcgcatctca tccattttgc
    44401 ccatgtagta atcgatccct tgatcatcac cagcacgagc agcatctgca cgcttctggt
    44461 tatagaggct catcagtttt ttatacccat ctccgatcgt ctgtttattt tccaaactct
    44521 tttctaaata ttggatggct tgatcgttca catacaattc agaaaattta agtccaactt
    44581 gttcataaag tttcgctaat ttatgcttat cttgggtagt ggaaatctct tgtttcaatt
    44641 gtgtaatctc tgattgaatc ttttcggtcg cttctggcga tagggctttt tcttcttttg
    44701 ccagaacttt tttcggttct ttttcttttt tcttaaaaaa tccaaacatc attttcccta
    44761 ctttcaatta aaatgctttc aaaactgggc ttaagatcca ggcatataag agtgctgcgg
    44821 ctactgtatc tacatcggtt gctgtagcat tgttgaatcc catcgaatta aagatcgtta
    44881 ctagcaaagc gggcaataat gtaataaaga aaccatgagc aataccgcca atgatcgctc
    44941 ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt ccctccggca aagaaattgg
    45001 ttagcatacc aggtaaaatc atcgctaagc cgaacatggg caaagtaaac atggcaataa
    45061 tcgtaccaat cgttgtcgta atgaaaccta aaatgacagc atttgggcta taaggaaaga
    45121 aaactggaca atctaaggca gggatcgcat caggaactaa tttcatagct atccctcgaa
    45181 atgccggcac gatttcacct aacagtagac gtacaccagc tagcaataca tacacaccca
    45241 ctacgaattg gatggcttgt aaaaaggcaa acatgatata gttttgatct cctgataatt
    45301 cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat atatagcggg accatcacga
    45361 ccatgacaga caaataagta tcttgcagaa attcgaaatg tgtcggcaac ttgatatctt
    45421 cgatcgactt tttattttcg cctttctcac caaaaagctt agcaacaccg gcttcaaata
    45481 agtacccgat cgtacaaaaa tgacctaaag caatatcatt tgatccagtg attttacgaa
    45541 tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca agctccgata aaaccaccga
    45601 ccaagatcaa tacgatccct cgcagaccgg caaaatagcc aaagactgtc gtcatcgttg
    45661 ccatccataa aattgcttga ccagttaaaa aaatgtactt ccattttgtg aaacgagcca
    45721 aaataatatt gaatacaaaa atggctaaga acgtcagtgc aatatctcta cctaaaccca
    45781 aatcattcat tgcttgacca ttgatagatt caatagaagg gatgatccct tgcatatgaa
    45841 atccttcagt aaagattttc ccgaaataag ttaaacttcc aacgatgatg ctcgaaccag
    45901 cactcaacac ttgaaatcct aggagtgtct ttaacgtgcc agagatgact tgtcctgctg
    45961 atttcttctg cagtagtaga cccaacatag caatcaatgc aatggtgatc gatgcctgag
    46021 tcaaaatatt ttcgatgata aaattgataa cgcccatgtt tttaccctct tttctttttg
    46081 tatttagata actcccttat cttgcagaac tggggtgatt ttttcttcaa tttcattttt
    46141 tgaaacaata tttttcaaat agatcatcgc cgttttagga tcaactgcga acttttcgaa
    46201 ctgcgaacga aaattttctg ctgtgatgat cacatctggt ttcatggaaa ctgcggaaga
    46261 aatatcacaa tggtccagtt tggcttctac tcctaatttg ttcaaaacat cctcagcaga
    46321 catctgtgct gcaaaactac ttcctaaacc tgcaccgcat acgaataaaa tgttcaattt
    46381 gttcatcttt gttctccccc gtatcattta ttatttctca actactgaaa aaagcagttg
    46441 tttgaaatct tcgatatttg tgcattcaat caatcgatcc aacttctctt cgttgttgat
    46501 caattcaatt agttctttca tgatgttcag atgcgagtag gagtctactg ctgccaaaca
    46561 aaaaataatc tttactggat ccatttcagg attaccgaaa tcgattggtt gctcaatcgt
    46621 agctacgctg actcctaatt tattgacccc atcttctggt cgggcatggg ctagtgccat
    46681 gtgtttgcca atcacgatat acggtccgta atcattcact gcacgaatca tcgcttcgac
    46741 atagcgctct tcgacaatgt tttctttaac caatggtcta gcagctagtt caatcgattc
    46801 ctcccaagta gtggcttttt ctttgatcat gatattgctg tccgtcaaaa tatcttttaa
    46861 cataggctgg atctcccttt tgttgatttc taaattgttt gtttcgaata atttttctaa
    46921 cttgccatag atgattcgat ctactcggcc accactttct ttcatgacat ctattatttg
    46981 agtgaataac tccgtcgatt catgactgtt aggctctaac cgctgtagtt cttcatttct
    47041 tttcaaaaag tcttctataa ccaagatatt cgtctcagtt aaaatcggat cgacaactaa
    47101 aagcggctta tttcgataat tcaattgaaa ggtgctgaaa accagattga catccaattt
    47161 atctactaat tcgatttctt ttgaacttaa aactgcagta atctcgatct gaggaaactt
    47221 ttctttcaga ttctctgcta acagatttcc agtagccatc ccatggttac agacaacgac
    47281 tgatttataa acataattca agtctcgctt gattacactg gcgatcgtcg aaaagtggat
    47341 gacaagaaaa gctatctcgt cctccagtat cttgccacca attacttctt cgatcgtagg
    47401 aacaaaatga gtgactgcgc ggtagattgg gaaataattt gttcggatgt tttctttcaa
    47461 tggattcatg acttggatat gattcttgat tcttacaatc agtgcagcca tgtgcttata
    47521 gagattttcg aataaagctt cttcctttag atggaaaggt acgtgtgtct cgttctctac
    47581 aaattggatc aattggatcg ttagtaattg agcttgtacc cactcgattg aattggagat
    47641 atctctagca ttgaacgtct caatagtgaa acgaagataa tttctttcta cttgcgggac
    47701 attgtccaat tgaaattcct cgatcatgtg gtcaataaat gcagaaaagc tactgtcttt
    47761 tatttctgta tttttccaat taatggcaga gataaattca tgtttcctga ttcgctggat
    47821 ccagatcaat gtaaaaagca ggatttgttt tttataaata tcatcttctt gtttcaacaa
    47881 cttattggaa tagatctcct gtattttttt gatttccacc aaaggaaaat aatggagaaa
    47941 gattttttga gccggtgtta attgtgcatc ttgattcata aagaagtcgg tcattcccag
    48001 attctgattg ataaaatcat agatcatcgt acggatagat cgttctgaac ctttataaac
    48061 cagtccttgc tttccataac tgacgatctc tatcccataa ctgaccagtg ttgctcgtaa
    48121 ccgtctcata tcttcatcta atgtactttt agagatttga aattcttctt cttttttgtt
    48181 tagatggatc gggattcggc tgtaagcaac ggctaaaact agatcaaaaa tacgttcgcg
    48241 ccgattcaaa aagccgtctt tcacatcttt tatttcagtt tctaatcgag cttgcttttc
    48301 cttttccagc ttcaacaaaa aacctttgtt gcgaattgta cggatctccg gaagcttttt
    48361 actgctcaac cagatattcg cttcaagaac ttcctgacgg atcgtccgct gactgacatt
    48421 gaactcactt gctagatgtt ttgcttttac tggatattgg gctgtcatga ttctgtgaag
    48481 tatttcaatt gttcttgttt tcatagaaat gatctccttc tgatttcaag tatatggttc
    48541 cgcttacata ataaaaagta gatatttctg ccacttgaag tggaaagaaa gtaagcaaag
    48601 caaacaaaaa ataagccata tgctttttca tctcctcaac gaaaaagaca tacgcctatt
    48661 attacaaaaa ttttgcccat ctatacaaaa aagaggttgt gaaaaagctg tcctgcatca
    48721 agtaataaga acaactaaac taaaatagtg cttcctattt ttcgtttggt tgttcttatt
    48781 atcgcagatg caagctttta aacaccattt agtggagagg ttgtgacaga gatgttcagc
    48841 cttgagcgat aagaagcgat tttgaaaaat cgcttcccat attttacaaa atcgtgcctt
    48901 attgccgata ggctatctct ggcacaccgt ttattcagaa aaaggagctg cgacaaggct
    48961 tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca gcataatcgg ctgaataaaa
    49021 tcggcttgcc atcttttttc tttctcagaa aaatcaaaat accatatctg agaaaaatac
    49081 tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt ttcgatcgac tgaataatca
    49141 cagcatctga aatcaattcg gatggcaaaa ctattttcgt ggatctgtcg ataatttcct
    49201 acttcctgaa tagttatttt tttagtatga tttcttacac cgtctgcttt gtttttttgc
    49261 agaactttct gatgttcggc aaacagcttg tctgtataac agcttctggc tttttcagga
    49321 gtttcttctt cccaagcgga ttggatcttc atgaatatct tttggatttc cagaaactgt
    49381 gctttctttt ctttagccgt tcctgacatg cgggacaata tctccgcttt cagccttttc
    49441 ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc ctcctactga caaaacagct
    49501 aatgcaagaa atcccgtttg ctcataacta gaaggacctg tacctggacc ataataccca
    49561 taagaatctc tgccgtaaga acgactgcca aaataactgc ccccatatga acgaccacca
    49621 aatgaacctc tgcccgaact tcgaccgcta gatgtacctc caccatgacc acccgcgaca
    49681 gcgaatcctt gggtcggcag agcaaacaaa cataggccca ctaacaaaat gattgctaaa
    49741 taattgattt ttttcattgt cttcctcgtt atcttttatt acaaaaaact atttttatga
    49801 tagccttgct aaaaggaaga gtcaataacc agatgcataa actgtttttt tagcaatttt
    49861 gtcttattta gtcattgagt aacatcggac aaatgtatgt gtcggcagtc cataattcct
    49921 ctatcttcag catgaacaag cttgcagaca agagatctgc gcttcctcca ggagagattt
    49981 ggttttcctg acaaaagtgc aacagtgctg taaatggacg atttggtaaa gcactttgac
    50041 tagcagcatg agcaagtttt tgcatttcca ctaacgtttt ctgatcactg cgatgcaata
    50101 cgcatgtgtc atctagcgaa ctcatcaaaa ctaacaacat atgcatttgt ttctgtacat
    50161 atgaatcatt atctagctcc ttagctgctt gaattgcaag cctgatatgc ggatacccta
    50221 atatcgcttc ttcatatgca ccatttacgc catatttttg cttcacccta tgaccatgag
    50281 tggttttttt atgacgatat tttgtatcag gaaaagcagc aagcttgctg acatcatcaa
    50341 gtattttcga taaagaaaaa ggctgttcca tactgatttt ttgtgcaatg acactgatca
    50401 atagccccat tgcccaaatc gctcctttat gggtattgat gccatttgta gcaatcagca
    50461 ttgccttttc cgcttttcgc ccaatctcag caattctttc tcttaactcc tgatcaatag
    50521 catgatgcca tgctatttga gccatttctt caaaaaaagg agttagcgtc ttagcagact
    50581 taagaaataa agcatagtcc atatcggaat gtgcacccgc atccagtgca tccactaatc
    50641 caggttttgg acttaatgtt acttctgcga tcaatgcttc ctctaccaac gcagcgagtt
    50701 gctgagtcac tgcttttttt cgttcgtcat ttatcatgac actcactcct tcttcctact
    50761 attacttgct gaaacctttt ttgatagcta cccaaatgat atgaagtaac cagcttaaag
    50821 caaatgcaca acttgccgtc attagataag ctacaagaat catgactcct gaaggtaact
    50881 gcagccaact atctttaaac aataataaca gtacttggaa aacaaataca ttggctaaat
    50941 acgtacgata agcataaaca gacaaccatt tgaacaatgg caattttggc gaatcgttta
    51001 caatcatttt ggaagcgcct atgaagacag caaagatgat gactaaactg tataaacttt
    51061 ggatcgtatt caagtaaggt gcattcgcaa agctcaagtc tcctggatgt gcgagcaatg
    51121 aacggacaga aaagaacgcg ataactaagg caacaggtaa gaaaagataa cgtactctgt
    51181 ccaaatattg atagactttt tcgtgataaa caaatgcggc taccccataa atcatgaaac
    51241 tagcaacaaa ccgatctaat aagtaccagc tgtcatgata aggcccagtc aatacttgtg
    51301 tttgatagaa cagataccat gcgacatata aaatcgttga accaatcaat actggccata
    51361 catatttttt attagcaaat actttgtaac cgagccaaac aaaaaacggc atgaacaatt
    51421 ggatctgcag catcataacg gtataccata aatgaggcgc tccatcacct gtgacatatt
    51481 tcagtaaaaa gcttgcagta tccgtatacg gagtttgttg ttggactgct ggaaatagcc
    51541 aaagataagc cgtcgtccat agaagatacg gaacgactag ttcaaaaaac ttttctttca
    51601 aaaattccca ataagacaaa tgctgacttg tttttaccat attataaaca attgcaaaaa
    51661 taaacattgg tgctgtgtat ttaacgatga cgtaaaaggt accaagaaaa gctgtatttg
    51721 ttgcgctgtg gctgtttgcc aaagcaaagc tcaatatcgt ttgcatcata acagccgtta
    51781 cagctgatac tttctggaag tcacttacgt tgattttgat ttttttgttt tcaaacatct
    51841 ctttctctct ctttttcttt attaccaaag ttctttggtt aatttaggtc cttcgactgt
    51901 tttcaataga atttttttct ctggctctct caaatactct tttagtgaaa aaccgccttg
    51961 ccgagtcact acttgggtat cgaattgctc aaaaaaagca ggatgcgatt gaattacctg
    52021 aattggcaat tcaatcggtg aatttgcgta cagcagcaaa tcaaaatcac tggtttcttt
    52081 tactgccgga atcccagtcg ataattcaaa tcctaagctg ccgccgattc cccatttaca
    52141 tcctgataat atgtttctag cagcatgaaa ttgctgataa acaggataat ccatgatttt
    52201 ctcttgtcta tacgattctt gttcgatgat gtcccacgga tgaatgactt gtttgacggc
    52261 atgttttgag atttctgttg accatctctg attgcgggca ggtccacgta aaccaatcgg
    52321 tagtatttct gcgtgatccg tcgacgcacg acgaactgtt ccgaacatct tttcagttag
    52381 aacgacccat tcaggcaagg tgaacccttc tatttcatgt ttatcaaaaa ggacaatatc
    52441 atgtgcttga atcatttttt atgcatccca ttcttcgtcc attttggcac ggactttatt
    52501 tgtttcgaca cgtccgaatg ttttggctgt ttcgtttgtg tatcgatttg tcagcatcgt
    52561 gtcatttgta ttgcggacat cttgaatggc ttcattgatt gcttcgatga ctttgctgac
    52621 attttgttct gaagcagctt ggtcggtgat atcttctagg aaatgataga tcgctcctag
    52681 ttttgtataa ttattgatat cgtaagcgat agctggaact ttttcagcag ctgcttcgat
    52741 ttcagcaacc gaacgttttg tcacacgtgc agcactttct ttagacatcg cttggacggt
    52801 aatttcttta ttgtttaaag caatcaagcg gcttgattgt aatccatgtg ctaaaaatgc
    52861 acctgaaata gcatttcctg caatcaatcc aataactgga tgtccagctt gacggagttt
    52921 tgcataagca gcagcactat tagccaaagc cacatggata ccgatcaatt cttcgttata
    52981 gccgtatgct tggcttggta catcgatcac aacgatgatt ggccgtttca cttttttgtc
    53041 tttatcttct tcgtaaacgt gatccaaaat ttgtcccatg cggaaacctt caactaaacc
    53101 aacttcaccg tttcgtacac ggtacatcgg gtttttagga tcaggtacga ttgatgtcac
    53161 gatggcttct tctatgaatt tacttgattt accataatac acagtactaa tagaagaagt
    53221 tggatttttc atgccagtta gtgccgcaaa ccaatcgtaa ccaacacttg ctgcagctgg
    53281 ttcatttcct tctgctactt ctggtaagtc aattgatttt gcttgatggt tagcaattgc
    53341 ttcattgtaa tcgtcaatgg ccattggttt tgaaagatct aaagaatcaa gtaatgataa
    53401 ataaaatgct gagctttcac tgcgatgcgt gtcttttcgt tcgtccattg ctgcgatgac
    53461 agcagctttg attgcttcta cactatcagt cactaattca tcaatgattt ttgattctac
    53521 ccgttgacga gatcctaatg tattccaaat caagtctttg tcactagaat caaattctcg
    53581 aacgcctgct tcttgttcaa taacttctgg tccattcaaa ccgactctcg ctttttttgt
    53641 tgcgattaaa taactcatta atgctgaagt aatcgacata ccgccaaatg atcctacacg
    53701 tcctggaatc aaaccgatga ctggtacata ttgttttaga gcaatgatta catttccgat
    53761 ttctgaaata gataacagtc cgtagtttgc ttcttgcaaa cgaacaccac ctgtatctag
    53821 tacaatgact ggaaagatct catttccttt tttattttct tctaacacat gttcaagtgc
    53881 agcaacgatt tttgcaccgg aaacttcacc gataccgcca ccttggaatt ttccttccat
    53941 agcgattact actgcttgtt tgccattgat cgtgccacgg ctgacaacga tcccgtcatc
    54001 actttcaggg acgattcctt gtgctggtaa acttggcgcg atgatttgat cgaatggatc
    54061 aatcaattca cgtccattgt caagtagagc gttcactcgt tctctggcgt ttaattctac
    54121 aaaactattt ttcatctgaa agttcctcca ttgcttgcgt caatcgtagg tacacaactc
    54181 ctggtgtagc accgaagtca ttgatcacga tatctgctga aattggataa cgatcaaaaa
    54241 atctcgttaa tacattgttc catacttcgc cgaagccatc gcttcctgta caaattttta
    54301 cagtagattc tgttttttct gttggaaaca tcaagatttc caaatctcct gaaccgacca
    54361 ctcctacatg gattttctta ttgatcggct gtttcgttgg atatttataa gctaattgtt
    54421 ccatggatct ctcccctttt tgtaaaacag agcatacacg ttctgcttat tcgtctttct
    54481 tcttccatct gggtaaatgg cgacaaaagg tttttctcgc caattttatg accaagttct
    54541 gaatttcatt ggtggttcat acaggccatc tgaccattcg atcaaatcat cgatggtttg
    54601 tgcagctaat aatgaacgtt tcgcttcact acgtttgatg cctagatctt ctggtaattt
    54661 cacgatgccg gctgcacgca agctatctag tgattctttc gtgctagtca ttccaagagg
    54721 tgtaacaccg ccaattgctg caattgctgc ttgtcgttct tcttttgttt ttgctttgta
    54781 caaataagca attccttctt ctgtcacgat atgtgtagta tcttcgctat aaatcatcac
    54841 tggtgcattg gctaagcctg cttgtttttg aacagctagt gcatctaatt cttcgacaaa
    54901 gactggtttt ttatttgaac catatgtttc aaccattcca cattcactaa gccatgtttt
    54961 ttataagagt catttacgac tttaccgttt acttttacct gtgtacctaa ataagcatat
    55021 actggtactg tcactttttg ctttttgttg cttgccactg tgtaagtaat gttattatct
    55081 gcagctttat acttcccttt ttcccacgat tctcctactt ttacttcatg tttttctaag
    55141 tgaggccttt cttttatcgc ttctgttggg gcgtaatcgt ataatcctcc catatctgat
    55201 gttgtataac gtgggagtgt ttcttcattg ataacaatat gaccgtgttt tgattggata
    55261 acttttgcgt aattttcttt tgctgctata gacgtgacga gtagaaacac cacagtagcg
    55321 ccaatgatta accatgaata ttttttattc atagtctttt tcataaaaac aagcgttatg
    55381 atcattgaag aaaaaaagat ttggatacct aagatacgcc aaggaaactg gagcaagctt
    55441 atcggtgttt tttgaaacaa aaaccatgga aataaattag ttacgcatac ccatgtagaa
    55501 actacgccaa catagatgat tttttctttt ttctccattt ctttcagtat gaataaagga
    55561 aaaatcaacg caaccaatcc taataacccc atagtgtatg ttgtaatatc gttatttaac
    55621 gcttgaatga tactatctga aatagaaagt gcttctagct gcaaatctgt tttgaaggga
    55681 ctgtgtattt cttgataatt catctgctgc aacataggat accaaaaata gctagttaat
    55741 gcacaagtca aaaaaacagc ctttactaaa ttcacgacca caaattttat atcgtttttt
    55801 atttgcttgc ttaaaaacaa acgaactata atcatacaag caatcaatgc actacacaat
    55861 agtgtagtta agacatgagt atacacaagt agacttatac tgacagataa agcgatgact
    55921 tttttttctc tattgaatat caatccataa gcataatata aaacagctgg aataatcgta
    55981 agagcgattg cttctgcaat tgcggatcga taatagatat caactgttcg ataagttgca
    56041 aaagtatata aacaactaaa taaaaaagca gcatctatct ttttaaaaaa cttttctcca
    56101 taataaaaac taatcagaat cgtacaaata tttaataacc aaatatata
//
LOCUS       DADVXB010000002        48552 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.002, whole genome shotgun sequence.
ACCESSION   DADVXB010000002 DADVXB010000000
VERSION     DADVXB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.002"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            14..928
                     /locus_tag="KB902_000053"
     CDS             14..928
                     /locus_tag="KB902_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806912.1"
                     /translation="MLKDLKQYYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLF
                     FSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESF
                     ENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEY
                     INDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKN
                     LSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILL
                     TIQEEKYKDSKIDKQIDDFPEEIIDRIE"
     gene            complement(1021..1755)
                     /locus_tag="KB902_000054"
     CDS             complement(1021..1755)
                     /locus_tag="KB902_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6806913.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            2081..2491
                     /locus_tag="KB902_000055"
     CDS             2081..2491
                     /locus_tag="KB902_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBB6806914.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAGRVSVNEMEENQID"
     gene            2484..3185
                     /locus_tag="KB902_000056"
     CDS             2484..3185
                     /locus_tag="KB902_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBB6806915.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            3185..4798
                     /locus_tag="KB902_000057"
     CDS             3185..4798
                     /locus_tag="KB902_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6806916.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHTFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKKTIKTITKKEKKDDI"
     gene            4788..5009
                     /locus_tag="KB902_000058"
     CDS             4788..5009
                     /locus_tag="KB902_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBB6806917.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDECDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            5006..5767
                     /locus_tag="KB902_000059"
     CDS             5006..5767
                     /locus_tag="KB902_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBB6806918.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEELSLRFPEIFAYALGDVRQMKELQQAVSKCQDRFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            6147..6656
                     /locus_tag="KB902_000060"
     CDS             6147..6656
                     /locus_tag="KB902_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6806919.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVVVGSVSTLLVLLINYKITSR
                     IKNMKIKIAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(6727..7266)
                     /locus_tag="KB902_000061"
     CDS             complement(6727..7266)
                     /locus_tag="KB902_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBB6806920.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVAVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(7406..8017)
                     /gene="rpsD"
                     /locus_tag="KB902_000062"
     CDS             complement(7406..8017)
                     /gene="rpsD"
                     /locus_tag="KB902_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBB6806921.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            8279..9130
                     /locus_tag="KB902_000063"
     CDS             8279..9130
                     /locus_tag="KB902_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBB6806922.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAYGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPAATILVEGMFANIVVNTAVLISMRMKEDAGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLAYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            9158..9793
                     /locus_tag="KB902_000064"
     CDS             9158..9793
                     /locus_tag="KB902_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBB6806923.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            9813..10586
                     /locus_tag="KB902_000065"
     CDS             9813..10586
                     /locus_tag="KB902_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6806924.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10994..11791
                     /locus_tag="KB902_000066"
     CDS             10994..11791
                     /locus_tag="KB902_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBB6806925.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            11769..12182
                     /locus_tag="KB902_000067"
     CDS             11769..12182
                     /locus_tag="KB902_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6806926.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEQEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            12166..14811
                     /gene="mutS"
                     /locus_tag="KB902_000068"
     CDS             12166..14811
                     /gene="mutS"
                     /locus_tag="KB902_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6806927.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAADVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            14829..16937
                     /gene="mutL"
                     /locus_tag="KB902_000069"
     CDS             14829..16937
                     /gene="mutL"
                     /locus_tag="KB902_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBB6806928.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEEPKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16959..17519
                     /gene="maf"
                     /locus_tag="KB902_000070"
     CDS             16959..17519
                     /gene="maf"
                     /locus_tag="KB902_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBB6806929.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(17604..19592)
                     /gene="treP"
                     /locus_tag="KB902_000071"
     CDS             complement(17604..19592)
                     /gene="treP"
                     /locus_tag="KB902_000071"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBB6806930.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            19815..20528
                     /gene="treR"
                     /locus_tag="KB902_000072"
     CDS             19815..20528
                     /gene="treR"
                     /locus_tag="KB902_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBB6806931.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            20605..21051
                     /gene="msrB"
                     /locus_tag="KB902_000073"
     CDS             20605..21051
                     /gene="msrB"
                     /locus_tag="KB902_000073"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBB6806932.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            21221..21823
                     /gene="ruvA"
                     /locus_tag="KB902_000074"
     CDS             21221..21823
                     /gene="ruvA"
                     /locus_tag="KB902_000074"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBB6806933.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            21836..22837
                     /gene="ruvB"
                     /locus_tag="KB902_000075"
     CDS             21836..22837
                     /gene="ruvB"
                     /locus_tag="KB902_000075"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBB6806934.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            22866..23444
                     /locus_tag="KB902_000076"
     CDS             22866..23444
                     /locus_tag="KB902_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6806935.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            23496..23978
                     /locus_tag="KB902_000077"
     CDS             23496..23978
                     /locus_tag="KB902_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBB6806936.1"
                     /translation="MTKILFVCLGNICRSPMTEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            24095..24469
                     /locus_tag="KB902_000078"
     CDS             24095..24469
                     /locus_tag="KB902_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806937.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(25269..26621)
                     /gene="brnQ"
                     /locus_tag="KB902_000079"
     CDS             complement(25269..26621)
                     /gene="brnQ"
                     /locus_tag="KB902_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6806938.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            26769..27359
                     /locus_tag="KB902_000080"
     CDS             26769..27359
                     /locus_tag="KB902_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6806939.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKSDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(27487..28836)
                     /locus_tag="KB902_000081"
     CDS             complement(27487..28836)
                     /locus_tag="KB902_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6806940.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(29004..29744)
                     /locus_tag="KB902_000082"
     CDS             complement(29004..29744)
                     /locus_tag="KB902_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6806941.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(29757..31349)
                     /locus_tag="KB902_000083"
     CDS             complement(29757..31349)
                     /locus_tag="KB902_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6806942.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(31917..32213)
                     /locus_tag="KB902_000084"
     CDS             complement(31917..32213)
                     /locus_tag="KB902_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806943.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            32389..33114
                     /locus_tag="KB902_000085"
     CDS             32389..33114
                     /locus_tag="KB902_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBB6806944.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            33107..33949
                     /locus_tag="KB902_000086"
     CDS             33107..33949
                     /locus_tag="KB902_000086"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBB6806945.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVSDRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            33952..34473
                     /locus_tag="KB902_000087"
     CDS             33952..34473
                     /locus_tag="KB902_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBB6806946.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(34726..35289)
                     /locus_tag="KB902_000088"
     CDS             complement(34726..35289)
                     /locus_tag="KB902_000088"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6806947.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            35540..35809
                     /gene="rpsO"
                     /locus_tag="KB902_000089"
     CDS             35540..35809
                     /gene="rpsO"
                     /locus_tag="KB902_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBB6806948.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            35997..38123
                     /gene="pnp"
                     /locus_tag="KB902_000090"
     CDS             35997..38123
                     /gene="pnp"
                     /locus_tag="KB902_000090"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBB6806949.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADTEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            38633..38899
                     /locus_tag="KB902_000091"
     CDS             38633..38899
                     /locus_tag="KB902_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6806950.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            39076..41034
                     /locus_tag="KB902_000092"
     CDS             39076..41034
                     /locus_tag="KB902_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBB6806951.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQTMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            41388..42689
                     /locus_tag="KB902_000093"
     CDS             41388..42689
                     /locus_tag="KB902_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6806952.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(42819..44189)
                     /locus_tag="KB902_000094"
     CDS             complement(42819..44189)
                     /locus_tag="KB902_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBB6806953.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(44371..44694)
                     /locus_tag="KB902_000095"
     CDS             complement(44371..44694)
                     /locus_tag="KB902_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6806954.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(45019..45627)
                     /locus_tag="KB902_000096"
     CDS             complement(45019..45627)
                     /locus_tag="KB902_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBB6806955.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            45957..46673
                     /locus_tag="KB902_000097"
     CDS             45957..46673
                     /locus_tag="KB902_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBB6806956.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            46686..47381
                     /locus_tag="KB902_000098"
     CDS             46686..47381
                     /locus_tag="KB902_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBB6806957.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            47465..48094
                     /gene="udk"
                     /locus_tag="KB902_000099"
     CDS             47465..48094
                     /gene="udk"
                     /locus_tag="KB902_000099"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBB6806958.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15776 a         8960 c        10059 g        13757 t
ORIGIN      
        1 aaaaacagaa aaaatgttaa aagatttaaa acagtattat cctctgtctg cttatgaaaa
       61 aaagaaatta ttccactttt tagcaatcaa cctgttggct gaacaagctg attctttaga
      121 tattgctagc aatcagtcgc tatttttttc ggatatagga ttttaccact taaaaggagt
      181 attaggagaa aaatccgtta tttttatcaa taagacactc tcttggcttt atcttcatga
      241 taaattggat caaaaatact tgagaaaaaa tgaagatgaa acaatcgaat ggttgaatga
      301 acgattcatt gaaagttttg aaaatcagtt taatctgttg cgagaagaga cgagccaatt
      361 gatccgaaga gagttaacca aaatacattt taaacttttg cattacacta ttaataaagc
      421 tgatgaattt ccacttgatg tttctttttt tagagaaaac tatccagcat tttattgcta
      481 tttgatagag tatataaatg atctaacgtc aaaacgcaaa gagttgcttc aagataaatt
      541 ttttcttttt ttcagttatt tattattatt gatcaatcac atacccattc aactgatttc
      601 tgaaccagta aagatcatca tcgatttttc ttatggtgct gcctataatc aatttatcaa
      661 gaaaaattta agcttgtaca ttaatctgaa cacggaagtg atagaggcag gaaagcctga
      721 gttcccggat gttataatca cgaataggaa taatctatat gaagaaagtg catctcaagt
      781 agtggtttgg ctcgatccgc caagagcagt agactggggg aatcttacaa agattttgtt
      841 gactatccaa gaagagaaat acaaagacag caaaattgac aagcaaatag acgattttcc
      901 tgaagaaatc atcgacagga tcgaatagtg aacttctttt agaaagtccg actgcttttt
      961 ctaaaaataa aaaaacttgg tacgcaatcg ctgtaccaag tttttttatt tagcttttga
     1021 ttaagccata aataataatt tatataagaa tactgctacg acaccagcac agataggtgc
     1081 tacaactggt acccatgcat atccccattg agaagaacct ttatgtttca atggaagaag
     1141 tgcgtgtaca agacgtggag caaagtcgcg ggctgggttt agtccaggac ctgtaggacc
     1201 accaagtgaa gcaactaatg tccatacaag gaaaccaagt gctaagtgag ctgtaccaag
     1261 attatcttgg aagaatggtg cttttgtaat acctagggca ccaaagaata aaacgaatga
     1321 accaaagaat tcattgacga aaccattgaa tttagaacca acgctgttga ttgttgagaa
     1381 tgtacctaac acatggttca cgtcttctgt ttggtcgtag taaggtttgt aacaagctac
     1441 tacgatcaat tgtccaatcg ctgcaccaat caattgtgca atgatataag gaacaacttc
     1501 agcccaaggg aatagaccat tagatgctaa agcaattgta aatgctgggt tgatgtggtt
     1561 accgctgatt ccaccaaaaa tcattgctgg catcataacc ccgaatccat acccgacagc
     1621 aatcagcatc cagtcactgc catatccttt tgtacctttt aaatctacgt ttgctacagc
     1681 accgttacct agaacgatta gtaatgctgt accaatcatt tccgccgcaa gacgggtcat
     1741 tagtgagtaa tccataaata cctccaaaag ttataaaaat gcaaaaaaaa agaaacatca
     1801 acacgaaaag catcggtgca gtgtttcgtg tcggaaggat ttctgcagtc ttaacaaatg
     1861 tgaataaaaa aatgaattcc attacttata agaaaccaga ccaacagtaa aactccaact
     1921 ctttttaaaa gttctccaca aatcaccaag cttaactata aatataccaa aaaaaaaacg
     1981 ttttttttct caaaaattgt atcttagaaa cagcatgttt tgaaactttc agaaaaggtt
     2041 tgttagtaaa atgaaagcta tacgtaagga gtgttgtttg atgaaatttt ttcaagagtt
     2101 tttcattatt attttctttt ctgtattagg agaaggcata cggatttttg ctcatttacc
     2161 tattcctgga agtatcttag gtattctttt tttattttta gcatttgaaa tgcatcttgt
     2221 tgatcctgaa aaaatcggag caactggtga ttttttattg aataatctag ctattttatt
     2281 tgttcctgct ggtgtaggtt tattggaata ttttgatgat attgcttcga tatggcctgt
     2341 tttactggga gcagtcgtcg tgtgttccat cgtcacgatg gttgcagcgg gaaaaacggc
     2401 agaaggtgta gaagctttgc tgggctatgt ccgtaagaaa aaagcaggaa gggtatctgt
     2461 aaacgaaatg gaggaaaatc aaattgactg agttttttgt gaatccacta tttggcttaa
     2521 gtttgacttt aggagtgtat gtattatctg ataaattttt gcggaaatat aaactgcctg
     2581 ttttgaatcc tctcgtatta tcgattgttg ttattatctt atttttgcat ttttctggga
     2641 tcagctataa agactataat atcgggggca attttttgac tatgctgatt actcctgcga
     2701 cagtggcact tgccatccct ctttataaaa acttccgttt actgaaagag aatttttatc
     2761 ctgtaatggc tgcgatttta gcaggaatag tcgcaaattg cttggttagt gtagggttcg
     2821 gttacttctt ctctcttcat aaagagatgg tgatctcatt actacctaaa tctgtaacga
     2881 cggctatttc tgtcgattta tctcatacga tgggcggggt gaatgccgtg acacttgcta
     2941 ttgttgtctc tacaggtatt tttggttcgc tgatcgccac tcatattttc cgcctattca
     3001 agatcgaaag tccagttgct cgcggtgtgg cgttaggaag tacttctcat gctattggta
     3061 cagcaaaagc aatcgagatt ggcgaaatag aaggaatcat ttccggactt gcgatatgcg
     3121 tcaacggaat attgaccgtt ttattgctac cgttattctt tcagcctttt gctggcttgt
     3181 tttgatgcga aaaccactat tttatgctac aataaccaaa acgttcgagc ataaaaaagg
     3241 agggaaagac gtgtatttgt cttccgagta tcttaaacaa tttgataaag atctatatta
     3301 taagattctc ctcctagaaa gttttgagga tcaagcttgg cataccgctg cacaattagc
     3361 gcaagttgtt cagctggatg cccgcagcgt gtcgaaatat ctgaacgagc tgtctaaaaa
     3421 ctatcagcag tttagcggta agacacaccc tttgtttaca aaaaatcacc gttctggtta
     3481 taacttttat gatacgctcg attcaattga acatgagcgt tttttgatct atctcgtgca
     3541 aagtacgctg aaattccagt tgctgcacga catttttttt gaagaattcc atacaatgta
     3601 ccaatttgcg caaaagcatt acattagtga atctactgct catcgaaaaa tcaatgaatg
     3661 gaaacagcaa ctgcaaactt acggaattcg gctgcaacga ggtacatata tcgctcaagg
     3721 cgaagaagaa atcattcgac tttacttgca tatgacattc tggcagttgt ttcgagggaa
     3781 aatctggcca tttgaaacga tttctcaaat ggacgtaaag aatatggcag aacatatcat
     3841 ggcttttttt aatgttcgtc tgaacgagat caaaaaaaga cgattggaat acatgctagg
     3901 tgcctttttt ttaagaaaat cacagaagca ttatgttgta ttgaatgaga aaaaaagacg
     3961 gctgatttct gacaatctgt tgttccagcg attttgccaa gtcatggagc cggtatttcc
     4021 taattatttt caagtagaag acgagttagg cgcattattt cttgtactga tgactcgtga
     4081 agaatattat agtgatccta agatacggaa gaaaattttt gattttcatc aacaagcaaa
     4141 aacaccgccc tttacagccc tttcagaagc aaaagccgct ctttctcttt atcaggaaga
     4201 gcaggggctg ccagcagaaa atctaacctt cgaggcagaa aactatttat tcagcagtca
     4261 ttttttcgcc tatctttttc ctaatgcgaa agaaacgatt gatggcaata gtagtgattt
     4321 tattaatcat ttagttattg aaaacaagga attgaaacaa tggctcgtac atttttttga
     4381 aagtagacac aaacatccca atcatctggc atttaaaaat catacgtttt tgatgggtcg
     4441 gtatctgact gtgtttaaaa cattaggagc ctttactcca cagcttccaa agatcacgat
     4501 tcttttaatg acagatttcc cattatttga agagcaactg ttagaggagg gattacggac
     4561 atttttccgt aatgagtatc agctgatttt tctgccaaca gattatcggg ggagagaagt
     4621 tgatcttctg atttcgacaa gtaaagtcca ccgcaaacca tgggcggatc ttgactattt
     4681 tattgtgacc gaagaactaa aattaattga ttacatccaa ctatctcaaa aatttgaaat
     4741 gattcaaaaa aaaactatta aaacaataac aaagaaggag aaaaaagatg acatttgaag
     4801 aaattttacc agaattgaaa aaaggtgcaa agattattcg taaaggatgg agtggatttg
     4861 aactttatgt tgttctcgta tccgatgatg aatgtgatgg ctgtccagtg acaccttact
     4921 tattgatcaa aacaagtgac gaaggttttt ccagcttcgc tcctacagtt tgtgatattt
     4981 tagcagatga ttgggcgatc gtagaatgaa aaaccagtat ccagatctag ctaaacaggt
     5041 tgtatttatc acaggagctg cttctggaat tggtgctgcg caagcccgag cgtttcttga
     5101 acaagatgct tttgtatttg gattagatca aaagttcggt aaaatggaag aactctcttt
     5161 gcgatttcct gaaatttttg cctacgcact aggtgatgtt cgacaaatga aagaactcca
     5221 acaagcggta tcgaaatgcc aggatcgttt tggtgaagtt acgattttac tgaatacagc
     5281 ggggatatta gatgcctaca aaccattgat ggaaactgac gaatcgctgt gggatctgat
     5341 ttatgagacg aatgtgaaaa gcatgtatca gctgacaaaa atcattcttc ctgatatgat
     5401 ccgccaaaaa agcggaacga tcatcaatat ggcttcgatt gctggcttga ttgctggtgg
     5461 aggtgggatc gcttatacaa gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc
     5521 tctggattac gcaggacagg gtatccgagt aaaaggaatt gctccaggag ccattcaaac
     5581 accaatgaat gcggctgatt ttgaagggaa aggtgagatg gcagagtggg tggcaaatga
     5641 aacaccagtc aagcgatggg cacagccgga agaagtagct gagctgacgt tatttcttgc
     5701 ctctcctcaa gcaagctaca tacaaggaac gatcatccca atcgacggcg gatggttgtt
     5761 aaaataacct tgtgtttttt tcaagcttct gtatgataaa actaaagaga gaaacaacgg
     5821 ttgatgataa aaaaagtcga tgactgttcc cgacattcga tgccgaacag ccagttcaaa
     5881 aaattctttt taataatcgt taatattcga aactaagcgg cttttcacga ccttttgata
     5941 taaacggtgt tcaaaagctt gcaactgcgg taacaagtcc agccaaatga aaaatataag
     6001 gagctatttt tatttgacta ttcttattac ttgttgcagg gcagcttttt cactaccttc
     6061 tgcggcactt cagttggaat tttcttccca tcctttggtc gcggtcatta ccaagataaa
     6121 attatcttgc aaaggagaaa tagaacatgg aaaaaaataa tacccgttca gccaaacgct
     6181 ggacaacgac agatgtgact cggatggcgc tagtcactgg tttatatgtg gcagtgacgc
     6241 tggttttgtc tgtctttagc tttggagtga ttcagattcg tctctcggag atgttcaact
     6301 atctgtcctt gtataacaaa agatacatcg tcgcggtaac agcgggagta gctttggcta
     6361 atattgcttc tcctcttgga ctgatagatg ttgtagtagg aagcgtcagc acgctgcttg
     6421 tattgcttat caactataaa atcactagtc gcatcaaaaa catgaaaatc aaaatagctg
     6481 tgacagcatg cgtatttgct ttttccatgt ttacagtagc tggtcagcta acgattttat
     6541 atcaactacc ttttttcttg aattggtggg tgattgcttt aggagaattg gcatcaatga
     6601 ttgtcggtgg gataattatt tattggatcg gtaaaaaagt ggatttgtca aaataaagat
     6661 ctgtttaatt taaaatatgg cagcatggaa gaagactttg agtcttcttc catgctgctt
     6721 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     6781 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     6841 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     6901 agcaagagag cccattagat tggcaaagat tgcatacaag taatgagcat ccgttctttc
     6961 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     7021 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     7081 aagtaaaaga taaactgcaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     7141 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     7201 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     7261 gttcataacg ccctcttttc gttaactaaa tatttttatt tggttaacga aattgtaaaa
     7321 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     7381 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     7441 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     7501 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     7561 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     7621 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     7681 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     7741 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     7801 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     7861 cagttaattg catgccgtat tctgattgtt tgccacggct gttaggtcca tgttgacctg
     7921 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7981 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     8041 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     8101 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     8161 agttattatt tttctgctgc attattttac acaaactaca gtatatgata gatcatccat
     8221 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     8281 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     8341 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     8401 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     8461 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgtatg gtctaggaaa
     8521 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     8581 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     8641 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     8701 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     8761 gttagaatca atagcagtaa aactagcaaa acctgcagca acgattttgg tggaagggat
     8821 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgc
     8881 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag ggtatgaaca
     8941 cgtgatagcg aattttcctg cctttacgct tgcttacttt gcttctcacg gacagatgga
     9001 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     9061 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     9121 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     9181 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     9241 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     9301 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     9361 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     9421 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     9481 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     9541 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     9601 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     9661 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     9721 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     9781 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     9841 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     9901 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9961 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
    10021 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
    10081 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
    10141 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
    10201 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
    10261 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
    10321 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
    10381 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
    10441 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
    10501 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
    10561 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
    10621 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
    10681 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
    10741 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
    10801 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
    10861 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
    10921 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10981 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    11041 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    11101 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    11161 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    11221 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    11281 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    11341 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    11401 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    11461 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    11521 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    11581 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    11641 gtttctgacc gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    11701 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    11761 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    11821 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    11881 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    11941 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    12001 cagaacaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    12061 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    12121 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    12181 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    12241 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    12301 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    12361 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    12421 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    12481 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    12541 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    12601 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    12661 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    12721 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    12781 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    12841 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    12901 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12961 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    13021 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    13081 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    13141 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    13201 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    13261 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    13321 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    13381 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    13441 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    13501 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    13561 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    13621 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    13681 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    13741 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagca
    13801 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    13861 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    13921 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13981 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    14041 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    14101 gatcggattt ttacccgaat cggtgcaagt gacgacttaa ttgctggaca aagtactttt
    14161 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    14221 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    14281 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    14341 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    14401 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    14461 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    14521 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    14581 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    14641 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    14701 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    14761 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    14821 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    14881 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    14941 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    15001 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    15061 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    15121 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    15181 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    15241 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    15301 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    15361 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    15421 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    15481 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    15541 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    15601 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    15661 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    15721 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    15781 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    15841 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    15901 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15961 agacaggtac ctttttcgta gaagaaccaa agaacacatt tgttgacaga attgttgata
    16021 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    16081 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    16141 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    16201 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    16261 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    16321 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    16381 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    16441 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    16501 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    16561 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    16621 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    16681 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    16741 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    16801 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    16861 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    16921 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16981 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    17041 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    17101 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    17161 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    17221 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    17281 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    17341 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    17401 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    17461 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    17521 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    17581 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    17641 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    17701 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    17761 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    17821 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    17881 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    17941 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    18001 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    18061 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    18121 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    18181 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    18241 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    18301 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    18361 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    18421 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    18481 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    18541 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    18601 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    18661 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    18721 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    18781 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    18841 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    18901 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18961 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    19021 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    19081 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    19141 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    19201 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    19261 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    19321 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    19381 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    19441 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    19501 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    19561 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    19621 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    19681 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    19741 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    19801 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    19861 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    19921 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19981 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    20041 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    20101 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    20161 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    20221 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    20281 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    20341 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    20401 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    20461 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    20521 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    20581 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    20641 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    20701 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    20761 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    20821 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    20881 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    20941 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    21001 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    21061 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    21121 ttgctatttg aaagaaacgc tccccagact ccttttttca caaggtgaaa tgtgctacaa
    21181 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    21241 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    21301 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    21361 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    21421 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    21481 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    21541 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    21601 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    21661 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    21721 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    21781 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    21841 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    21901 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21961 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    22021 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    22081 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    22141 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    22201 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    22261 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    22321 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    22381 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    22441 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    22501 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    22561 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    22621 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    22681 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    22741 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    22801 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    22861 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    22921 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaatgaa gcaaaaatca
    22981 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    23041 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    23101 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    23161 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    23221 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    23281 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    23341 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    23401 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    23461 tggaaaagca atgatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    23521 tgggaaatat ttgccgttca ccgatgacag aaggcttgct gagaaaacga atagcattag
    23581 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    23641 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    23701 tggttgctcg gcaaattaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    23761 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    23821 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    23881 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    23941 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    24001 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    24061 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    24121 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    24181 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    24241 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    24301 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    24361 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    24421 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    24481 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    24541 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    24601 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    24661 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    24721 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    24781 gttaagtttt tttgcgaaaa ctatttttat atcatatata tgtctaaaat ctatattata
    24841 aaagaaatgt tgtttgatca gcttctcttc ggtattagtt caaaacaaaa cggcaaagta
    24901 tatggagcta ctttgccgtt ttgtttctct aatactcagg tcagtttata gacgctcaat
    24961 aaacggtgtt caaaagccag tttctcggta ttaagtcaaa tttatgcaaa aatgtgagaa
    25021 gccattttca caaaatattt cttaatactt gaaactaagc ggctttttca cgacctctca
    25081 ataaacggtg ttcaaaagtc agtttctcgg tattaagtca aatttatgca aaaatgtgag
    25141 aagtcatttt caaaaaatat ttcttaatac tcgaaactga gcggcttttt cacgacctct
    25201 caataaacag tgttcaagag acagcctatc ggcaataagg ctgaacgtct ctttcacaac
    25261 ctcttttatc aatctgctac ttcttctttc ttagcgaaac tccaaatcag tccgataaca
    25321 aaaccgataa ctgctggtac gatccacccc atccccaatt tgaaaaacgg caagtagctt
    25381 tccgcaacat ataaaagatt ttgaacaata ggcgtttgtt tgatagtttc tgggcaagcg
    25441 ttcaacccat caaaaatcga agcaatcaat gtaaaataag tagtcattcg ataaacagcc
    25501 gtacgctgct taaacaaagg accaactaac actagtaaaa tcagtgtcat tgctaatgga
    25561 tagatgaaca tcaaaacagg caacgaaaat tgaatgatat tcgtcaagcc tacgtttgcc
    25621 gctaaacaag gaaggatact agcaagtgca acaaagaatg cgtaatttct ttgcggaaac
    25681 aaatctgtga atgtttctgc aaaagctgta atcaaaccaa taccggtctt caagcaagct
    25741 aatataacga taaatgctaa taagatactg ccataagtac ctaaataatg atcagcaatc
    25801 tgagccagcg tgatcccgcc attttcactt agagcaaagc tacctaagct catagcacct
    25861 aaataagcga gcaaagtata aatgattccc atcaatataa tgctgatcgc accagatttg
    25921 atcgtgtctt tagcgatttc agcaggtttt gttacaccca tgttttggat tgttgtgaca
    25981 atgatgatcc caaatgctaa agcagcaagc gcatctaatg tgttatatcc ttgagtaaac
    26041 cctgtgaaaa aagcatgctc ttgataattt ggctgaatag gcgcttgatt tacagaacct
    26101 agtggattca aaaaagcaag gagaagcaaa gcacctaata aaaccaaaaa tgcaggattc
    26161 aggaactttc caacataatc taatatcttt gtcggttttc ttgaaaacca ccaagccagc
    26221 acaaaaaata caatactgaa aattgctaga tatagcgtct gtctgctagg atcgataaat
    26281 ggtgctaaac caatctcgaa agatgtggtt gcaaggcgag gtaaagcaaa aaacggtccg
    26341 ataactaagt aaagcaagat ggtaaaaacc atcgcatatg tttgatttat ccgttttgct
    26401 aattcatata cacctgagct tttcgataca ccaatggcaa tcacccctaa gaagggaaga
    26461 ccgataccgg taaccaagaa acctagattc gcccaaaagg tagcagcgcc tgcttcttga
    26521 cccaaatgaa cgggaaagat aagatttcca gcaccaaaaa atagaccgaa aagcatggag
    26581 cctataaaaa gatagtcttt aaatgataat ttttttgtca tacataactc ctttacggtt
    26641 ttttttaaaa gtaacaaaat ttcgaaaaat atgcaacaat tttcagaaaa tttcctatat
    26701 aaaacgatgg ttatttaata acgtaagtga taaaataaaa gcgctgaatc atctgaggag
    26761 gaatcatcgt gacaaagtcg agattagaag catttactga tggagtggta gccattgttt
    26821 tgagagttct tgtattagag atcaagatcc ctaatacatc tagctttcat tctttatggg
    26881 tcatccgaaa tacattatta gcttatacca tcagctttat atttgttgcg gtgatctggg
    26941 tgaaccatca tcgtatattt cagatggcag aacgaattaa ttaccgagtg gtctggtcga
    27001 atatcttttt gctcttttgg ctgactttat gtccttctgt tactagttgg gtcgggcgta
    27061 accctgaagc tttttggcct gagatggctt atgtcttagt atacacgatg tggagttttt
    27121 cttttggtat cttgatgagg caaatcatga aagcaaataa atcagattcc catgtcgtga
    27181 gagttttgtc aaaggaccgt cgaagtctta tctccatgat gattaactta tgcttgattg
    27241 ccggtgtctt ttttgtaccg ttgatcgggt tattcggacg tttttttgta tctggtattt
    27301 ggattttttc ctataaaaaa gcagatgcct attatcagcg gttgtttccg gggaaataga
    27361 aaagaggctg ggacagaagc ttttaactcc aagaaataag ccgaaatttc acaaaaattt
    27421 aagaagcaat tttcgtaaat tccttcttat ttctcgaagc tgaccacttc tgtcacaact
    27481 actttcttac ttcttacgtt catatttcat atgatagatt agtaatagaa gcaagaacca
    27541 cacaggtgtt agtaataaag cgattctcgt atcttttcct aggaacaaga cgacacacac
    27601 aaaggccatg taaagaaata ccagataatt actaaatggg tacaacggca ttttaaatga
    27661 atgagctttt ttgccgagga tacttttacg atatttcatg tgcgtgtaga caagcatact
    27721 ccagataaac aagaaacaag tagtggcaat actgcttact agtgtgaata cttcactagg
    27781 catcacgtaa ttcaagataa cagaaatgaa aatgacgata gtagaaaatg tcaaagcatt
    27841 ccctggcaca tgatgtgttg ttaacttttt gaatttttta ggggcactgc cttcttgcgc
    27901 taaagaacga agcatacgtc ctgtactata tattgcactg ttgcaggcag aagctgctgc
    27961 acttaatacg actaaattga tcaaggaagc agcaatcgtg atcccaattt ccgaaaatac
    28021 ttctacaaat ggactgttat ctggattcaa gctgttccat ggatagattg ccataatgac
    28081 aaaaagagat cctaagtaaa ataagatgat cctgatagga atattattga tagcttccgg
    28141 caacactttt tcaggatttt ctgtttctcc agcgactaat ccaactaatt ctatcccagc
    28201 aaaagcaaag gttaccattt ggaaagctaa gataaatcct tttgcaccag ttggaaagaa
    28261 tccgccatga gaccatagat tcgtgatact ggctgtgcca atatctgtcg tatagtgggt
    28321 gaggatcata taagctccta cgaggataaa ggcaatgatc gctacaactt tgatcaatgc
    28381 aaaccaaaac tctaactcac caaacaatga gacagccacc atattcaagc aaagaagaag
    28441 acctaatgca atcagttcag gaagccactg aggaacacca ggcgcccagt agcgtacata
    28501 cattccgatg gctgttaaat cggccattgc aatcgatacc cagcagaacc aatacgtcca
    28561 gccagtgatg aaagccgctt ttttgccaag atattctgca acaaaatcca gaaaagaatg
    28621 gttattggtg tttgataaca gaagttcgcc taacgcacgc ataatgaaaa aacagatgca
    28681 tccagtaata agataggcga gcaatatcga agggccagct agctggatag actttccgga
    28741 acctaaaaac aaccccgttc caatcgctcc gccaatagaa atcagttgga catgtctatt
    28801 tttcagtcca cgctgcagtt cttgctcttc attcattttt aaatcatcct aactaaaaaa
    28861 gtttaattac ttccatatta agagagtttt ctgaaaaaca caactaagat tccaaaattt
    28921 tcagaaattt accttttatg agtaattcat aaaaaagaac tgcggtaaac accgcagctc
    28981 tttgtcccaa tcagctattg atcctaagca tttaaaatac gtgaaaggaa ttcttttgta
    29041 cgttcttctt tcggatggac aaagatatct tctggtgtac cttcttctgc aatcacacct
    29101 ttatccataa aaatgacacg gtcagataca tcttttgcaa attccatctc atgcgtcacg
    29161 ataagcattg tcaagccagt atgtgctaag tctttgatcg tattaagcac ttcgccaacc
    29221 atttcagggt ctaacgccga agtaggttcg tcgaatagca atacatctgg attcattgat
    29281 aatgcccgag caattgcgac acgctgtttc tgtccaccag ataattgtgc tggtttggct
    29341 tcgatataac gatccatacc aactttttcc agattttcga ttgctacttt tttggcagtt
    29401 tctttatctc gtttcaggac agttgtttga ccagacatac agttttccaa gacattcata
    29461 ttgttgaaca ggttgaagga ttggaaaacc atacctagat tcgttcgata tttaggtaaa
    29521 ttatatttag gagctaatac attttctcca ttataaatga tctcgccgcc tgttggtttt
    29581 tccagtaaat tgatacagcg caagaaagta gatttaccag aaccggaaga accgatgatc
    29641 gtcacaactt cacctttatt gactgttacg ctgatatctt tcaatacttc attttcaccg
    29701 aagctttttc ttagatgttt gatttcaata attttttcat tcatgattct tcctccttat
    29761 tcctgcaaat ttgaattgtc gatttcttca agcttggtat aagctgaagg accatcgatt
    29821 ttcttttcta ccgcccgcag gattctggtg atcgtaaagg tcatgactaa gtagatgatc
    29881 ccgacgatcg taaatgtttg gaagaattgg aaattcgcac cggaagcaga gtttccttgg
    29941 aagaacaaat cagctacgcc gattacactt aaaactgctg tatctttgat attgataaca
    30001 aactcatttc ctgttgctgg caagatattc cgtaaaactt gtggaataac aacttttctc
    30061 atcgtttgac catgggtcat accaatggct tgcgcagctt cgaactgccc ttcatctact
    30121 gcaaaaatcc ccccacgaac gatctctgtc atgtaagctc cagtattgag agagacaata
    30181 aacaaagcgg caatcgttcg gttcaatgaa atgccaaaag cgagtgccag accgtagaag
    30241 atgaccattg cttgtaccat catcggtgtt ccgcggaata cttcgacata gatagaaaga
    30301 agtgcatttc cgattttttg gaagaagcga gtcagtgcat ttcctgattc aggtaccgaa
    30361 cggaagacac caatcagtaa tccaagtgta gtaccgacaa ctgtcccgat caatgcgatg
    30421 aacaaggtaa gtccagcacc tcgtaagaac atattgccgt attgtttcca aatcgtagtg
    30481 aaatcagaaa tgatgccagg tttttcttca ctatcagttg cagcaggctg atctttgact
    30541 gcttggtcca taattttggt tcgttcatcg ttagagatgc cagaaagaat ctggtttact
    30601 ttttggatat ccgggtcgcc tttacgcata ccaacagaaa tctgaacatc ttccgggttt
    30661 gtctggaagc catctgcacc gctgaattca agcatttcca agtctttgtt cacactagtt
    30721 gccgttacac cttccggacg ttcgctgaca taaccatcga tcattccaga agctaaagct
    30781 gttctcattg ctgagaaatt atccattgct tgttgtttct gcacatctgg tatctgatcg
    30841 atcacagtat agtggaatgt atttaactga gcagtgatct ttgctccaga aagatctgct
    30901 aaactttttg cttttgcata tttgctatct ttttgaacta ctactactaa ttgtgattcg
    30961 taataaggat cggtaaaatc aatttctttt cgtcgttcag cagtagggct cattccggcg
    31021 atgatcgcgt cgatcttgcc tgattgaagg gcaggagcca gaccatccca tttcgtttgg
    31081 acgatgacta attttttccc taaaccatct gctacttttt tagcgatttg aacatcataa
    31141 ccgccggcgt aactattttg gccttgaatt ggcaaggcat tattctcatc tgtttgttga
    31201 gaccagttga agggtgcata cccagcctcc atacctacgc gaaactcatc gctcggtgtt
    31261 ttttcatctg catttgccag agatcccaca ctgaatagtg agaagacaaa agcaaatagt
    31321 acggcaactg aaaccatatt ttttttcatt tttttctccc tttctgatta tatgatacac
    31381 gagcggtcta gatgaaatgc ggtaaagctt tatctgaaaa aataaaaagc gaccgattta
    31441 tagatataaa aaggccgcta aaattccata aggtgataaa cctctcacaa aacatagcgc
    31501 aacttagcat cactgctaag acagtccgca agctcttaac ttgcgtccca acatacactc
    31561 caagcaaaaa agtgcacatt tcggcgatcc tccctattcc tgcttctcca tgtttgcttc
    31621 actccacagg gttaatgatt ctcgcgacct ctacctcatt gattgaggca tctcgtattc
    31681 agttatttat acaaaaaaag tttacgatac tcgagaggct ttgtcaatct ataactgctg
    31741 gtttttgaaa aaatactgat aaatatagaa atctttactt ttaccgaaaa aacaatcaaa
    31801 atgtgaatca tctatccatt gcaaacgata gtataattat acacaaaaat gtatgtaata
    31861 caataaaaaa agaactagaa cagaaaattt cctgtgtcca gttccatctc gatcatttaa
    31921 gctgccgctt tctttggctc acgtcctagg atcgcttgca aaagaacaac gacgccataa
    31981 atggctaata ttagataaat caaacttgag tattgggtga ttccccagcc ccatgttcga
    32041 tatacggcta atgtaatggc taaaacaatt gcggcaatca cgttgaataa agcaaaagcc
    32101 caaagatttc cattttcttt gcgtacaaga taaaaaacag agaaataaac gcttaacgct
    32161 aaccaggcga tacaagccag aataacgccc caataaataa agaatggtaa catatcgatt
    32221 cacctcactt ttatacagca gtattgtaac acgttttcat tcttttgtca gtgaacattg
    32281 tgataaattg ctcaaatgcc cataacactt ttttattccc atttttctga cttttcaaca
    32341 ataaatttgt tcgagtatgg gctataatgg aaagtgaggt gacaaaacat gaaacaatta
    32401 acagtagacg aagcagcaaa agagatatta gcttatcagc aaattacatt tttgaccggt
    32461 gcaggggtat ccacaccttc tggagtgcca gactatcgat ctttgtcagg aatctaccac
    32521 gggatggagc agccggaata cttgctgagt catcaagcaa tggtgaatga accggataaa
    32581 ttctatcaat ttgtcaaaaa gatttatcat cctgaagcaa aacccaatat cattcatttg
    32641 gaaatagcac atctagcgaa agaaaaaaat gtttgggttg tttcccaaaa catcgacggt
    32701 ttgcacgcaa aggctaaaag cccgcaactc gtcaattttc atgggagtct gtatcaatgt
    32761 cattgtcgaa aatgtcaaca aacggtagac tggaaagaat atcttcacag cgacaaacat
    32821 caagcatgcg gaggacaaat acgcccagac atcgtgttat atggtgaagg gtttcaagat
    32881 ggagtcatgg agcaggcggc ttatgccgtc agccaagcag agctgatcgt cattgttgga
    32941 acgagttttc aagttcatcc gttttgtgat ctggtacagt ttcgccagcc gtcagccaaa
    33001 atcttagtaa tcaatcaaac gcctgtttat ttagcggagc cttatacgtt tattcaagaa
    33061 gacggagcgg ttgttttcaa aaaaatacaa gaattaggag cagattatga ctgaattcaa
    33121 aaccgaaaaa gaaaaaatga ttgcaggcga gctttatttt gccaatgatc ctgagctggt
    33181 ttccgaccgt atgtttgcaa gaagtcaaag ccaaatcatc aaccaagcag aatcagcgga
    33241 actgcgatcc caattgttga aagagacttt tggccgtaca gggaaaaaaa tctatatgga
    33301 gccagttatc aattttgatt acggatataa tatatttgtt ggggagaatt tttatgcaaa
    33361 tttcaattgt acatttttag atgtcagcac gattgaaatc ggtgataact gcatgttcgc
    33421 tccgaatgtc cagctttaca cggcgacgca tccactacat ccagtgaaac gtaacagcgg
    33481 tctggagtac gcaaaaccca ttaaaatcgg taataatgtt tggttaggcg gaggagttat
    33541 cgtcacgccg ggtgtcactc taggggacaa cgtagtagtc ggcgcaggtt cggttgtgac
    33601 caaatctttt cccgacaatg tagtgattgc aggaaatcct gctcgtatca tcaagacagt
    33661 agaggaagaa ctaacagaag agtctcttga aacattacgt cataagatcg atatgatcga
    33721 tcgagagttg gttgctttat tagaaaaaag aatggatacg gtaactaaaa taggacaagt
    33781 gaaaaaagaa gaaaaccaag cagtttatga tgcaaaaaga gagcagcaag tattggataa
    33841 agttgttagt ctgctgaaaa ataagggata taaggaaaca ataacagaca cgtatgttga
    33901 tttgatgaaa cactcgcgcg aataccaaaa caaaatgaag gaggaataag tgtgatcgaa
    33961 ggagagacac ggcgaaaaca aatcatgcaa accttggcaa atacagaaaa accagtgagt
    34021 gctagcaagt ttgcgaaaac ttttggagtc agccgtcaga tcattgtagg cgatattgct
    34081 ttactacgag ctgcaggtaa aagtatcgtg gcaacagcaa gaggttatat cctcgaaaca
    34141 gaagaaacca atactgggca catcagtaaa atcgctgtcc agcatggaaa agatcaaaca
    34201 gaagaagaac tgagactaat cgttgaaaat ggtggtgaaa tcattgatgt aattgtggaa
    34261 catccccttt acggtgagtt agcaggaact ttgcacatca aaacgccaca agatatcgat
    34321 tcctttatga gacgttatca aaaaagtaat gctactttgt tatccgaatt aacaggcggc
    34381 atccatctgc atacgatccg ctacccagaa aagcatatgc tgaaaaacat caaacaaaaa
    34441 ctagctgaag caggaatcct ctacgaagga taacatcgta gctgctactt tttatcctag
    34501 aaactattct atcatctctg agataaacac ccatatggaa gaaataagaa aaaataagaa
    34561 aagatgcgta tccaatacac agaatttttt ggaattgcga tttctagatg tctatctaaa
    34621 tttcgattag tggagaaaca taaaaaaggg aagtgcagct tttgagcact cccctttttt
    34681 ataaagcttt cttgtagcat agtatcgaag gaacctgcca attctctact cgatcaccaa
    34741 tacgccttct tttagtgcaa atggattttg atcgttgatg tggtcataga acatcacacc
    34801 gttgatatgg tcgatttcat gttgaacgac gatcgattca taattcttca aacgaatctt
    34861 gtgtttttca ccattcatat cataataaga cacagtgatt ttggcatggc gaacaacata
    34921 tcctggtact tctcgatcaa cagataaaca gccttcacct tcccctaaac aagcatcttg
    34981 aacagaatgg ctcaaaattt taggattata cataacagta cttagagaag gtccatctgc
    35041 ctctgggtca ggacttggta cgtgaacagc aatgattctt ttagaaatat ctaattgagg
    35101 agcagctaag ccaacaccgc ctcgtaagtg tagttcttca gctttgattg gatcttggct
    35161 gttttttaag aactcaagca tctcttttcc taaagagata tcttcttcgc ttaatggaag
    35221 agaaacttct tttgcaactt cgcgtaaggt cggatttcct tcacgaatga tatcatccat
    35281 tgtaatcatg gaatatgtac ccctttctta aaagactgtg tttcaagtct attttcgcat
    35341 tatagtttac cacaaaaatg gaaaagtagt agtaagattg tttgaaaact accttttctt
    35401 aatgattaac tacttgattt tcaacccggt ttcaggtaaa gtatagctgt gtgctctagg
    35461 cacatgacct gccacttggt taagcgaatc accaacgttt tactcagtcg caggggaata
    35521 atcgaaagag gtgaaagaaa tggcaatttc aaaagaacgc aagaatgaaa tcatcaacga
    35581 atacgctcgc catgaagggg atactggttc tccagaagta caaatcgctg tattaactga
    35641 agaaatcaac cacttgaatg aacatgcacg cgtgcacaaa aaagaccatc attcataccg
    35701 cggcctaatg aaaaaagttg gtcaccgccg taacttgtta gcttacttac gtaaaactga
    35761 cgttcaacgt taccgcgaat tgatcaaacg tttaggcttg cgtcgttaat tttagtcaaa
    35821 aagagtggga ttcacatgaa tctcactttt tttactcgta tatcaattaa gtaaaattcc
    35881 gtgatcaagc tagatggact cctactaacc aaatgaaagc tgctcaaaag acggctttcg
    35941 gcagttttca tttgtttagt agcgtcttgc tttcacgaga aggaaaagga gaagttatgt
    36001 cagaaaaaca agtattcaaa acgacatggg gcggccgtcc cttacaaatc gaagtcggtc
    36061 agctagcaaa acaagcaaac ggagccgttt tagtccgtta tggagataca gtagtcttaa
    36121 gtgcagctgt ggcctctaaa gaagcaaaag atacagactt tttcccatta acgatcaatt
    36181 atgaagaaaa aatgtatgca gcagggaaaa tccctggagg tttcatcaaa cgagaaggcc
    36241 gtccaagtac ggaagcaaca ttgactgccc gtttgatcga ccgtccaatt cgcccgatgt
    36301 ttgcagaagg cttccgtaat gaagtccaag taacgaacat cgtgatgagt gtagaaacag
    36361 actgctcgcc agctatggca gcaatgctag gttcttcttt agcactatca atctcagata
    36421 tcccatttga cggcccaatc gcaggcgtag aagttggtcg tgtaaatggc gagtacgtct
    36481 tgaatccaac agtagaacaa gcagaacaaa cagatatcga attgactgtt gccggaacga
    36541 aacaagccat caatatggtt gaaagcggcg cgaaagaagt ttcagaagaa gacatgcttg
    36601 gtgcattgct gtttggtttt gacgctatca aagagttagt tgctttccaa gaagaaatcg
    36661 ttcaagcagt agggaaagaa aaaatggaag tgactttact gcaagttgat gaagtattga
    36721 aaaaagaaat ctttgatgct tcttacgcta caatgaaagc agcagtaatg actgaagaaa
    36781 aacttgctcg cgaagataat atcgagcagg tgaagatcga tatccgcgaa gcttatgctg
    36841 agaaatttgc aggtcatgaa gatgaagatc acttgttgaa agaagttaaa caaatcacag
    36901 aagatcttga aaaagatgtc gtacgtgaat tgatcaccat cgataagatc cgtcctgacg
    36961 ggcgtaaatt ggatgaaatc cgtccattgt catcagaggt cagcttattg ccacgtgtac
    37021 atggatcagg tttgttcaca cgaggacaaa cacaagcttt atcagcttgt acactcgcac
    37081 ctctaggaga gcaccaaatc attgatggtt taggggtgga agtcagcaaa cgattcatcc
    37141 accactacaa tttccctcaa ttttctgttg gttctacagg acgtgcaggc tctccagggc
    37201 gtcgggaaat cggacatggc gcattaggtg aacgtgcgtt agcacaagta atcccttcag
    37261 aagaagaatt tccttatacg atccgtttag tagcagaagt attggaatca aatggttctt
    37321 cttcccaagc aagtatctgt gctggcacat tagcattgat ggatgcaggt gtaccaatca
    37381 aagcgccagt cgccggtatt gcgatgggac ttgtttctga tggtgaaaac tatacgatcc
    37441 taactgatat ccaagggctg gaagatcatc ttggcgatat ggactttaaa gttgccggta
    37501 caaaagatgg tatcactgct ttacagatgg atatcaagat tcaaggaatc acagaacaaa
    37561 tcctaactga agcattaact caagcaaaac aagcacgtat ggaaatctta gaagaattga
    37621 cttcaacgat tgctgctcca cgtgaagaat taagccaata tgcaccaaaa atcgaaatga
    37681 tccagatcga acctgctaaa atcaaagatg ttatcggtaa aggcggcgat acgatcaacg
    37741 gaatcatcga tgaaactggt gtgaaaatcg atatcgatca agatggaaaa gtaagtattg
    37801 cttcagctga tacagaaatg atcaaaaaag ctatcaagat catcgaagat ttgaccaaag
    37861 aagtcaaagt tggtgaagtt tatctaggga aagttgtccg tatcgaaaaa ttcggtgcat
    37921 tcgtcaactt gatcaaagga aaagatggac ttgtccatat ttcccaatta gcaaacgatc
    37981 gtgtcaataa agtcgaagat gttgttaaac taggtgatga gatccttgtg aaagtaactg
    38041 aaatcgataa acaaggacgc gtaaatctgt caagaaaagc aatgttgaac gaagatggtt
    38101 caacgaaaaa tgaagaaaaa taatttaatt cataggaata atgtacttgt gatcgtgaag
    38161 gtgacagggg gacaataatt attcgaaaaa aggggactgt gacaaaagcc gtgtcacagt
    38221 cctttttttt cgaataaacg gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa
    38281 gttaaaaaca ttaggagctg tttttacttg gctgttctta ttacttgatg cagaacagct
    38341 tttttacaac ctctccaata aacgatgttc aatcagctgt ccctcgatat tagctcaaaa
    38401 aacggcaaaa tatgaggaac tatttttccg tttgtttctc taatactcag gtcaaaccgc
    38461 tgatttcaca acctctgatt cacggtgttc cagaagcagc ttctacggaa ataagctgaa
    38521 cacttttgtt acaacttctt tttttctgga gtttcttggc gcatattttt ggagtccttc
    38581 tgaataaagc gtaaaataaa agtgagaaat atggataaag gagggaaagg agatgctgaa
    38641 ttttttatgg tcgttattta tcggcggtat attaggtttg atagctggcg caattttagg
    38701 aaaggaagtc ccgggaggcg tatctggaaa tatcattatc ggttttttag gtagttggct
    38761 cggcgaattt ttactaggac cactgggacc ggaactcggc ggtttttatt tgataccagc
    38821 attattgggt gcaatttttt gccttgctct ttattcattt gtggcaagac gtatcagaga
    38881 acgtccaaag aaagaataat tttattcaaa taagttgaca cttcagtgtg ttacttggat
    38941 aattagaagc aatttaggaa agcgggtgtc atggataaga atatcatcta tcattcaagc
    39001 ttacctaaag gatatccata taacaagaaa tgagggaaaa acgtggcaac aacgcacaat
    39061 accaaaaaga tatcaatggc tggcctgctt gtagcgatgg gagtcgtcta cggagacatc
    39121 gggacaagtc cgctttacgt tatgaaatcg attgttgaag ataatggcgg attgtcagga
    39181 atcaatcctg attttgttat cggatcagtc tcattgattt tttggacatt gactctactg
    39241 acaacaatca aatatgtcgt gattgcattg aatgcagata accatggtga aggtggaatt
    39301 ttctcactct acacacttgt ccgaaaaggt gggaaatatt tgatcattcc tgcaatgatc
    39361 ggaggagctg ccttactagc agatggggta ttgacccctg ctgtgacggt aacgactgcg
    39421 attgaaggct tgcgaggaat tccgcagttt tttgaccggt tcggtaataa ccagaacgtg
    39481 atcgtcatta tcactttagt tattattttt gttttattca tggtccaacg ctttggtaca
    39541 gatattgtcg gaaaagcatt cggaccaatc atgttcgctt ggtttacttt tttaggcgta
    39601 atgggattaa tgaacttcag tcaagactgg acagttatcc gtgcactgaa tccttattat
    39661 gctatccagc tgctttttag tgcagataac aaattaggct tgttcattct tggaaatatt
    39721 ttcctggcta cgacaggtgc agaggcgctt tattccgatc ttggacatgt cggcaaacga
    39781 aatattcgtc tgagctggcc ttacgtcaaa atttgtttgg ttatcaatta ttttgggcag
    39841 gctgcgtggt tgttgaatgt ttatcaaaac cctgaagcac agcaaatcaa gaacctgaat
    39901 ccattcttcc aaacgatgcc tcaaagttgg atcgtgatcg gcgttgcttt tgcaacagtc
    39961 gctgcagtca ttgcttcgca agcattgatt acaggttcgt ttacgctagt ttcagaagca
    40021 atcaagttga aactgctgcc tcggttaaag atcatgtatc ctgggaacag tatcgggcaa
    40081 atgtatatcc cagcagtcaa tctgatttta tggatcgcct gttctctagt ggttgtcaca
    40141 ttccgaacgt ctcatcatat ggaagctgct tacggtctat cgatcactgt gacgatgttg
    40201 atgacaacag cactgcttta cttttatctt atccaaaatg ggcattctcg ttggcttgca
    40261 tatttagtta cctttttctt cggtgcgata gaagtcgttt tctttatctc aagtgttgtc
    40321 aaattcttcc gaggcggttt tgtagccgtt ctgattggtt tgatcatctt agtcgtgatg
    40381 tttatttggg aacaagggaa cattattcgc gaatcgtcaa ccgaggatgt gtctttgaga
    40441 gattatatcc cgcagcttag agaattacgt gatgatactt ctttaccaat ctatcagaca
    40501 aatgtggtct tcttggttcc tgatatggct gaagataaag ttggccgaca gttcatctat
    40561 tcgattttag ataaacggcc taaaagagca cgagtctatt ggtttgttca tgtggaagtg
    40621 acggatgagc catatacgaa agaatatcaa gtagatatga tggacactga ttttattgtc
    40681 caagtgaatc tgttcttagg tttcagggtc caacaggaaa tcaacgtata tgttcgccaa
    40741 gtcatccatg atttgatgaa acaaggccgt ttgccaaaac agccacaaag atactctctg
    40801 acaccagggc gagaagttgg cgatttccaa tttgtcctga ttgatgaagt agtttccaat
    40861 gtgacaactc taggaaaatg gcaacgtcaa atcatgcagg caaaactggc aatcaaaaaa
    40921 atcgctacct cgccagaaac atggtttggg ctagagtaca gcgaagtaaa acatgaaact
    40981 gttccgctta tcattggaaa tactcggaaa acatggttga aagagcggtt gtgaaagtag
    41041 cgctttgacc tgaactaatg tcgaatgtca gctacttgaa caccgtttat cagaggtcat
    41101 gaaaaagctg tactgcaaca agcagtaaga acgagcagat aaaaacagct tctcatgttt
    41161 ttcatctgtt tgggcttaat gccgcagatg caagcttttg aataccgttt ttatcagagg
    41221 tcatgaaaaa gctgtttagc aacaagtaac gcaatgattt tgaagtgata aggagatgtg
    41281 gctgaaaaat gccgcatctc cttttttatt cctaaatatg aatacgcatt attttcaatc
    41341 tttttgtaga aaaagggtac aatagaaaaa gagaaaggcg ggagaatatg gttatcaatt
    41401 tcattatttt atttttgatg attgcaatta cttcattttt tgtagcaagt gaatttgctt
    41461 tagtgaaaat cagacgatca agattggaac aactagaaaa ggaaaatgta aagaacgcca
    41521 agctagctct tcatgttaca caccatttag ataactattt atcagctagt caattaggaa
    41581 ttacgctaac cggtttgatt atcgggtggg tcggtgaagg atctgtcgcg gctttactag
    41641 aaccagtgat cggtaaacta ccttttagtt cggctattag cagtacaatc tctgtggcgc
    41701 tgggatttat tttagttacg tatatcgatg tggttattgg cgaactgctt cctaagagct
    41761 atagtatcgt caatacggag aaggtcgtct tgttcgtagt taaaccactt cattattttt
    41821 ataaagtaat gtttcctttt atttgggtat tgaatcattc agctgcaggg ctagggaagc
    41881 tattaggtgt gcgtctcgta tctgaaggag aagagacatt gtctcaagaa gagctgacat
    41941 tagtcgcatt gaattcttat gaaaaaggag agttgaccaa agaagaatat cattatttgg
    42001 aaaacgtgtt tgaatttgat gataccttgg caaaagatat acaagtagac cgtacgtcca
    42061 tgcaagtatt cgaagcttca gaaaccgtca aagaagcgat aaaagcttcg attgaacaag
    42121 gacatactcg ctatccggtt atcttagaat caaaagacaa tgttttaggt tatgtcacct
    42181 tgccagattt gatcaagcaa tcttataaag atgaccagct gacagtagaa cagttgattg
    42241 aagagccgat cgtaacaact gaaacgatcc ctataaaaaa attattgacg atcatgcgaa
    42301 aaaagggaaa gcatattgct atcttaaaag atgaatacgg agggacaagc ggcttagtga
    42361 cgattgaaga tattttagaa gaaatcgtcg gggaaatccg agatgagaca gatttggacg
    42421 aagcattgat agcggaacag tcagatggct cttatatcat ctccggcaaa ctaacattag
    42481 atgatttcca gcgttatttt catgtagaga ttccagagtt tgaagaaacg aattttacta
    42541 cacttgcggg ctttgcttct agccgatata aagaaataaa agcaggaaca atcattgaga
    42601 ttgcatcatt ccgtttcacg gtattagaat accagcatgc acatatcgat tatttcaaag
    42661 tagagtccac ggaaagaaaa acagaataaa agaaaaaagg ctgtgacatt ttttgtcaca
    42721 gcctttttgt tatctaaaaa acctgttttc ggtaaacgaa gaagatattt tcaataaaag
    42781 ttttcatttt tagccgcaac gatttctttt aatcaaggct atcttgcttc tgcatgttct
    42841 aatgtgaaat gttcctcttc acccatgtgt ttcaattgtt tcatcgaacg catataagag
    42901 taaagcaaca cggcaacaga accgatccaa gctaaaggag aagctgctgc tgctcctggg
    42961 tatccccaca ttcctgtaag aacgatagct gcaaaagaac gcataagcaa ttccatcata
    43021 ccggcgatcg tagggatctt gctttgtcca agcccttgaa gtgtgtagcg taaaatgaac
    43081 aggactgcta agatccagta aagagaccca ttgatattga agtaggtttg tgctaattca
    43141 aatacacgtg tttctgatgg gctaacaaac aattgaacaa agaaatgacc gaagaaaatg
    43201 acgatagcac ctgctaagag actaaatccg acactcatca gtaaagtttg acgtacccct
    43261 tgcaagattc ggccatattc tttcgcacca tagttttgtg cagtgaaagt tgccattgca
    43321 ataccaaatg acatcatcgg ctgatttgca aattggtcga tacgaccagc agcggcttga
    43381 gcagctacga catctgtccc tagactattt agtgctgctt gtaacacgat agcaccaaca
    43441 gcgatgatcg aagattgaaa cgccattggc aaagcagcat ttaggtgtac agcaaactct
    43501 tctttttcaa atttgaaatc ttttttgcgt aactgtaaca aaggcatttt tttcttgata
    43561 tacactagac acagtacgct ggaagaaact tgtgcgatta ctgtagcaat agctgcacct
    43621 tccacaccca tgccaaaata gataataaag atcaaatcaa gtacgacgtt gatgatgacc
    43681 gcaatgatca gaaagaatag tggtgtgcgg ctgtcaccaa gtgcgcgaat gacattagaa
    43741 agcaaattga aactgactga tgcaaagatc cctaataaaa taattgaaat aaatgtttgt
    43801 gcttgatcaa gtatttcagg aggagtttgc atcaattgaa gcatcggacg aataaacagg
    43861 agacttagga cagttaaaat cacagtgacg acaagactaa tgacaacact agcagcaaaa
    43921 cttttcttca gaccccgata atcttttgca ccgtaacgtt gtgcggtaat aatggctaaa
    43981 ccagctgtta aaccttgggc aaagccaatg atcaaaaatg tcaggcttcc agttgcacca
    44041 accgctgcca gcgcattttt acctagcgtc tgacccacga tgatcatatc gatcatattg
    44101 tagaactgct gaaaaacatt tccgatcagt aaaggaacag tgaacatcaa aatcagttta
    44161 gcggggcttc cttttgttaa atcgcgcatc ttttaaactc cttatatctt taaaatttag
    44221 ttagtagtat atagcgttta tcctgagaat accaattaga aatcaatgat aatttatgaa
    44281 actccataaa aagaagccaa gaattgagtc aaagaatcaa caacttggcc tggtctgtaa
    44341 aataagggac atccacgttt atctatcacc ttaatattgt ctaatctcac ttggtaaaag
    44401 gatcgtttct ctcgtaccgt catcataggc gtatacttga gcaggaaatt ggttcgaata
    44461 ggcaaacggc aaatcaatat ccatttccac attgcttcct gcttgagaaa aatgcatcgt
    44521 cacttttcca cgattttcga tcaaatcaaa ggttaatata ttttctaatg gaatgactcc
    44581 cttaagatct aggtcaataa taaaccatat actgtcaatc aattcatctg gcaaacttga
    44641 tacgacacca actgaagcgt aacggttgcg gctgctatca aaactttcaa acatctgttt
    44701 aacctccttc gaatcaacga atgttttatt tttataatta atcctaggat aaactagaaa
    44761 tacttacttc aacgagggtt cattctaata aagaatcagg aaaaatgcaa caataattga
    44821 atactttttt tcaaagtata aatttttata aaggtacgat aaaagtatgc gaggaaaagc
    44881 ttggtaaatt aggatttttc gtttgtaaag ccatttacaa aagtggaagc cccatatgaa
    44941 aataaacgat tagaaataaa aaaggcgtgt taaaagctgc tgacccgccg cttctaacac
    45001 cacctgattg tttcagtatt attcttctgt tgaaccgatc acttctggtt cgccaccttc
    45061 acctgtgctt tcttcttctt cactttgagc gactacagca gcgatttgct cttcactgtc
    45121 ggtcacgaat ttgtaatcgt cgttttttgg aagatcggct actgtaatag aatcacctaa
    45181 ttccaagttt gtcacgtcaa cttcaattcg ttcaggcaat ttgtctggtg tagcagatac
    45241 gactactgta tacaagtttt gagctaacac tccaccagat ttagcaccca ctgattcgcc
    45301 aacaagaacg acttctgttt cgacttctgt ttcttccgac atgtttacag atagaaattc
    45361 tgcatgttcg aaatgattgg taaaagtgtt cgtttggatc ttgtgaacca atgtattgac
    45421 tttttgtcca tcgatgtcca tcgtgatgac tgtgttcgct ccatgttcac gcaacaattt
    45481 gcttagtgtc aaaccatcga atgagatagg ggtactttct actttatacc cataaacaac
    45541 agctggaact ttcccttcgt gacgaagttt gtttcttaat gaacggggac gtacttctct
    45601 tttacttact tctaatgata ctgacataac caaaattcct ccttaaaatg tgactgtctg
    45661 ctttggtaac ggacagattt tatttaagtg aattctaaag gctaatctcg tgcacatcat
    45721 cgaaggcagg gcgcttaaaa aagcgcaaaa ggagagatgc gcgcatctcc ccttagaaag
    45781 tcaggattca acttttctcc accaggtcat tacgctgtgt atgagaaatc caattcactt
    45841 tactatttaa ccgtaacgtg aactgttaat taagtcaagg aataactatg atgatgtatt
    45901 tgcaagcaag aatattcaag gtataattaa ttagtagtaa taagaaagga aacagcatgc
    45961 gtttagataa attaatagaa gaaaaattag aaacgacacg caaggaaatg aagcggctat
    46021 ttgctttgaa gcaagtgatg atagatggca cagtcgaatt tcgacaaaat cgaaatgtag
    46081 atagtttact gcatcaaatc gaagtagcag gtgaacactt agaaacaaat gagtcctatt
    46141 atcttctcaa taaacctgaa aaagctgtta cagctgtatc agatccagaa aagacgacag
    46201 taatcgatct gattgcaagt gccgatcgtt tccaaccatt atatccagtg ggaagactag
    46261 atagagatac aacaggacta ttgctgatca cttcgaatgg acaattggga tatgaaatgc
    46321 tacttccaga aaaaaaggtt tcaaagactt atcaagtagt tgtgaacgaa agggtgacac
    46381 cggcagacgt aacagcattt gaaaatggaa tcgtattcgc tgatgggtat caatgtaagc
    46441 cggctgattt aaaaatactc aaagcagaca agcaccaaag tacggtttta ttgacgatcc
    46501 aagaaggaaa attccatcaa gtcaaaaaga tgttcttagc ccaaggaaag aaagtgaccg
    46561 cattgaaacg gctaagcatg ggaccattgg aattagatga acagctagga gtaggcgagt
    46621 atcgatcgtt gacattagca gagatgaaaa agttaagtat ttattttaaa taggaggtca
    46681 aaaagatgaa atataaaact ttattgttcg atgtagatga tacattgtta gattttcaat
    46741 taactgaagc caatgcttta agtgctttgt ttgcagaaca aggaatcaca ttgacaccag
    46801 aaatcgaaac cagctataag gctttgaatc atcatttatg gcaggagttt gaaaaaggca
    46861 gactatcacg agaagaaata ataggcagtc gttttgggtt acttttccag caatttggga
    46921 aaacagtaga tagtgatcaa atggaaaaac gctaccgcca ctacttgaac caaggtcatg
    46981 atcttgttcc aggaagtcta gaaatcctga aaaaggtcca tccgcatgct gatctttata
    47041 ttgtgacgaa cggtgtgtcg cacacgcaac atcggcgatt aacagatgca ggaatgcttg
    47101 attacttcaa ggatatcttt gtctcagaag ctgtcggagc gcaaaagccg atgaaagaat
    47161 tttttgatca tgtcttttcc cacattccta attttgataa aaagcaaact gtgatcattg
    47221 gtgattcttt gacttctgat atcaaaggag gaaatatggc agggatcgat acgatttggt
    47281 tcaatagaaa taaattacca gaaatcgaag aaatccagcc tacttatcga atcgattcat
    47341 tagaggaact ttattcatta ttggaaattg aaaaggatta attttcagaa aaatatagca
    47401 ttttcgtgtt ttttcgctat aatagattag aatgaaaaaa cggatacgaa agaggtttta
    47461 gtcaatgaca aaaagcaagc caattatcat tggtgtgacg ggtggatccg gaagcggaaa
    47521 gacaagtgtc agccgtgcga ttttcaacaa cttcccggac cattccatca tgatgcttga
    47581 acaagattct tattacaagg atcagagcca tttgagtttt gaagaacgat tgaacacaaa
    47641 ttacgatcac ccatttgcct ttgataatga tctgctgatt cagcatgtag gcgacttact
    47701 gaactataaa gccattgaaa aacccgtgta tgactatgta gcgcatacaa gaagtcaggc
    47761 aacgatcatt caggaaccaa aagaagtgat cattctagaa ggaatcctga ttttagaaga
    47821 cgaacgtctg cgtgacttga tggatatcaa agtatacgta gatacagatg atgacattcg
    47881 tatcattcgt cgtatcaaac gggatatgga agaacgggga cgcacattgg actccgtgat
    47941 cgaacaatat ttgacagttg ttaaaccgat gtatcatcaa tttatcgaac caacgaagcg
    48001 ctatgcggat atcattgttc cagaaggcgg agaaaaccac gttgctattg atttgattac
    48061 aacaaaagta gctagtttct taaaccataa atagtgcgca gcgaaacagt tgaacggact
    48121 gcgaccgttt gaaaagcaag gattctgctt tttgaacagt caccagccaa ctgttttttt
    48181 atttataaca agaggttgtg aaaacagcat cttgacctaa gtattaaaaa gaagaaacgg
    48241 aaaatagctg tttatatttt accgtttttt gagctaatac cgaaggtcag ctgattgagc
    48301 accgtgaagt agaggttgta aaaaagctgt cttcgcatca agcgataaga gcatccaaat
    48361 aaaacagctc ctcacgtttt tcgttgggtt gggcttatta tcgtagatgc aagcttttga
    48421 acaccgttta acgagaggtt gtaacagaag tggtcagatg caataaataa gaagaaactt
    48481 acgaaaatta tttctcgaat ttgtgtgaga tttcgactta tttttttgaa gaagctcttt
    48541 tgtcgcaccc cc
//
LOCUS       DADVXB010000003        48115 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.003, whole genome shotgun sequence.
ACCESSION   DADVXB010000003 DADVXB010000000
VERSION     DADVXB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.003"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..201)
                     /locus_tag="KB902_000100"
     CDS             complement(<1..201)
                     /locus_tag="KB902_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6806959.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFT"
     gene            complement(223..1197)
                     /locus_tag="KB902_000101"
     CDS             complement(223..1197)
                     /locus_tag="KB902_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6806960.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            1497..2369
                     /locus_tag="KB902_000102"
     CDS             1497..2369
                     /locus_tag="KB902_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6806961.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIIIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(2951..5149)
                     /locus_tag="KB902_000103"
     CDS             complement(2951..5149)
                     /locus_tag="KB902_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6806962.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESEQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            5381..6373
                     /locus_tag="KB902_000104"
     CDS             5381..6373
                     /locus_tag="KB902_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6806963.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            6433..7854
                     /locus_tag="KB902_000105"
     CDS             6433..7854
                     /locus_tag="KB902_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBB6806964.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPDKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            7847..9346
                     /locus_tag="KB902_000106"
     CDS             7847..9346
                     /locus_tag="KB902_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBB6806965.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            9385..10779
                     /gene="uxaC"
                     /locus_tag="KB902_000107"
     CDS             9385..10779
                     /gene="uxaC"
                     /locus_tag="KB902_000107"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6806966.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            10938..11621
                     /locus_tag="KB902_000108"
     CDS             10938..11621
                     /locus_tag="KB902_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBB6806967.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            11623..12459
                     /locus_tag="KB902_000109"
     CDS             11623..12459
                     /locus_tag="KB902_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6806968.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            12470..14224
                     /locus_tag="KB902_000110"
     CDS             12470..14224
                     /locus_tag="KB902_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6806969.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(14500..14841)
                     /locus_tag="KB902_000111"
     CDS             complement(14500..14841)
                     /locus_tag="KB902_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6806970.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(14909..17080)
                     /locus_tag="KB902_000112"
     CDS             complement(14909..17080)
                     /locus_tag="KB902_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6806971.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            17249..18148
                     /locus_tag="KB902_000113"
     CDS             17249..18148
                     /locus_tag="KB902_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6806972.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(18219..19076)
                     /locus_tag="KB902_000114"
     CDS             complement(18219..19076)
                     /locus_tag="KB902_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6806973.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(19061..21763)
                     /locus_tag="KB902_000115"
     CDS             complement(19061..21763)
                     /locus_tag="KB902_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6806974.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(21776..23065)
                     /locus_tag="KB902_000116"
     CDS             complement(21776..23065)
                     /locus_tag="KB902_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBB6806975.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            23215..24261
                     /locus_tag="KB902_000117"
     CDS             23215..24261
                     /locus_tag="KB902_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6806976.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24263..26416
                     /locus_tag="KB902_000118"
     CDS             24263..26416
                     /locus_tag="KB902_000118"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBB6806977.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(26889..28340)
                     /locus_tag="KB902_000119"
     CDS             complement(26889..28340)
                     /locus_tag="KB902_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6806978.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(28337..30061)
                     /locus_tag="KB902_000120"
     CDS             complement(28337..30061)
                     /locus_tag="KB902_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6806979.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(30054..30668)
                     /locus_tag="KB902_000121"
     CDS             complement(30054..30668)
                     /locus_tag="KB902_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6806980.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(31013..32470)
                     /locus_tag="KB902_000122"
     CDS             complement(31013..32470)
                     /locus_tag="KB902_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6806981.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(32511..33431)
                     /locus_tag="KB902_000123"
     CDS             complement(32511..33431)
                     /locus_tag="KB902_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6806982.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(33443..34390)
                     /locus_tag="KB902_000124"
     CDS             complement(33443..34390)
                     /locus_tag="KB902_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6806983.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(34869..35588)
                     /locus_tag="KB902_000125"
     CDS             complement(34869..35588)
                     /locus_tag="KB902_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6806984.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(35637..37283)
                     /locus_tag="KB902_000126"
     CDS             complement(35637..37283)
                     /locus_tag="KB902_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6806985.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            37462..38052
                     /locus_tag="KB902_000127"
     CDS             37462..38052
                     /locus_tag="KB902_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6806986.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            38144..39649
                     /locus_tag="KB902_000128"
     CDS             38144..39649
                     /locus_tag="KB902_000128"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBB6806987.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(39733..41085)
                     /gene="celB"
                     /locus_tag="KB902_000129"
     CDS             complement(39733..41085)
                     /gene="celB"
                     /locus_tag="KB902_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6806988.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(41085..41603)
                     /locus_tag="KB902_000130"
     CDS             complement(41085..41603)
                     /locus_tag="KB902_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806989.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(41619..41945)
                     /locus_tag="KB902_000131"
     CDS             complement(41619..41945)
                     /locus_tag="KB902_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBB6806990.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(41958..43937)
                     /locus_tag="KB902_000132"
     CDS             complement(41958..43937)
                     /locus_tag="KB902_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6806991.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(43958..44272)
                     /locus_tag="KB902_000133"
     CDS             complement(43958..44272)
                     /locus_tag="KB902_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBB6806992.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            44440..44733
                     /locus_tag="KB902_000134"
     CDS             44440..44733
                     /locus_tag="KB902_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBB6806993.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(44811..45923)
                     /locus_tag="KB902_000135"
     CDS             complement(44811..45923)
                     /locus_tag="KB902_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6806994.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            46310..46489
                     /locus_tag="KB902_000136"
     CDS             46310..46489
                     /locus_tag="KB902_000136"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6806995.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            46683..46853
                     /locus_tag="KB902_000137"
     CDS             46683..46853
                     /locus_tag="KB902_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6806996.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(47277..>48115)
                     /locus_tag="KB902_000138"
     CDS             complement(47277..>48115)
                     /locus_tag="KB902_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6806997.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        14430 a         9718 c         8552 g        15415 t
ORIGIN      
        1 tgtgaagtac gttttcgtca aaggaaacgt ttcttttgag cgcagccatt ttctaatcac
       61 tgcaaccatc gcatacgatg caggaccgaa agtaaaaact cccaaacctg cgatgactaa
      121 accgccccac agaaaattca aataaaccaa ctgtaaaata cgatttagcc ttccgtttat
      181 tttatctaat gactgcagca tatctttccc tctctttcta tcttagtaaa cgccgtcttc
      241 tcctagcttt ttggcaatct tattagctaa aattaccata aacaatccta cgaccccttt
      301 aaacaatccc attgctgtac tgaaacttaa ctgtccattc ttcaatccag ctgtataaat
      361 ataggtgtcg aaaatttctg caacgcttcg attcaatgaa ttcaataaca agtacatatg
      421 ctcgaaccct aagtctaatg tctgaccgat ttttagaatc agcaaggtaa tgattactgg
      481 acgaattgcc ggcaatgtaa catgccatgt tttgcgtaag cgtcctgctc catccatttc
      541 tgcagcttca tacaactgtg tatcgactgc agttatcgct gaaagataga tgatcgtaga
      601 ccagcccaac tctttccaga tcacttgtcc gatatatact gtgcgtgtcc attcagggga
      661 tgttagaaaa ctgatttttt caaatcccat tgttgcaagg aattcattca atacccctcc
      721 gtcaacattc aaaaatacat aagtaatcga aacaatgatt acccaagaca tgaagtgagg
      781 gatgtaaatg atcgtttgaa tcccgttttt caatcgtttg ttcgttactt catttaatag
      841 taaagacaaa atgattggca tcggaaaaaa cacgaagata tttaatccga acaaaatcaa
      901 cgtatttctt aataatgtaa agaatgtcgg ttctgtaaac aaacgaatga aatgtttgaa
      961 accgacccaa ggacttccca ttattcctaa aaatggttga taatcttgaa aagcaataac
     1021 gagtcccccc ataggaagat acctaaaaat caagaaataa aggactcccg gcagaatcat
     1081 cacatataaa aatttattcg ttttgattcc tgcaattatt ttttttcgtc ttctgagctt
     1141 ttcttctttt ttcgatagcg tcagttgaaa tggttcttgt ttctttacac tttccataag
     1201 cccctcctta gttttgtgaa tgtttgctgc ttatgacttc atgatagata actatctgaa
     1261 ttacgtatat aatcattttt atcgtatgta aaaacgctta catagaaatg atttttgtgc
     1321 tatgcaaaac gataaagtgt attttttcac aaataaacta cgcatagcaa accttctatt
     1381 tttttctatc tgacacttag cataggaaat gattatatac gtaatctttc accgatgata
     1441 aattgaacat atagaaacag aaacatttaa tttattttga ggaggagcct atctatatga
     1501 aaaagaaagt ctctatagga gaaagaagtt ttacactttt caacaatacg tttctaattt
     1561 tgctagcttt gatctgtatc gttccttttt taaatatcat cgctacatct tttgcttcta
     1621 cacaagaagt cgtcgcgaaa aagtttatcc tttttcctac taccttttct ttagacgcgt
     1681 atcgctacat tctttctacg ccgaccattt ttagagcact tgctgtttcg attggtgtta
     1741 caggtgtcgg aacgatcgtc agtatgtgtg caacttcact gatggcctac ggtctttcca
     1801 gaaagtattt gtttggtcga ggtttcgtca actttcttgt tgtattttct atgttgttca
     1861 gcggggggat gattccaacg ttcttagttg ttcgttctct aggactggtc aattcttact
     1921 gggccatgat cctgcctgtg gctgttaatg caatgaatat gatcattatg agaaactttt
     1981 tccaagcctt gccggatagt ttggaagaat cagcaaaaat ggatggttgc acagattttg
     2041 gtgtattttt caaaattatg ctgccattag cgttaccgtc tattgctact atctcgcttt
     2101 tttatgctgt tacttactgg aacacttata tgactgctat tttgtatatc aacgattcat
     2161 ctaaatggcc gatacagatt cttttacgcc aaatcatcat tgtatcaagt gggatgcaag
     2221 cagaaagtag tgccgttgat gtgattccac cagcacaaac agttaaaatg gctgttatcg
     2281 ttattgcaac agtgcctatg ctgattgttt atccttttgt tcagaaatat tttgtcaaag
     2341 gagcactcgt aggttctgtc aaagggtgat tatgtactga acgcaaaatg gtagttgtgt
     2401 cagaagtggt cagcttcaag aaataagaag gcatttacga aaattgcttc ttaaattttt
     2461 gtgaaatttc ggcttatttt tcgaagaatc tactcctgga acaccgtgta tcagaggttg
     2521 tgaaagagac gttcagcctt gagcgatgat aaaaactctc acaaacattg cgacgagtaa
     2581 cccacaggag caataagaag cgattttgaa aaatagcttc ccatatttca caaaattatg
     2641 ccttattgtc gatagcctgt ctcttgaacg ccatttattc gtaaaaaaga actgtgacaa
     2701 gacttttgtc acagctcttt ttgcgtgctt agccttgaaa tttaactatc cataaataca
     2761 aatactaggg ttattctaac ttcttttatt gcttgaatca gtccacaaga aaaacagcct
     2821 cttgattaaa cggcgtttat cttgttgatt ctgcggcaat aaaatcagcc agcagcaaaa
     2881 catgaagtgc tgttttttgc tgtcctcttt tattgcttga atcagatcac aagaaaaaca
     2941 gcctcttgat tcacaaatat ttttttcgat attctcccgg cgtaatcgat tccttctttt
     3001 taaagaaacg aataaaattt tgcggatttc gatattgcaa tctttctgca atctctttta
     3061 cggagaggtt agtctctttc aaccattttt ttgctacctc taaacgatga ttttgaacaa
     3121 aatcaccaaa tttttctcct gtttcctttt taaatacatt acttaaatag ttagggttat
     3181 aatgcaacct atcagcgatc acatctaaag acagatcacg atcatattct gtgtagacga
     3241 tatgcataat attctccgac aaatttttaa attcatgatc agtgattgct tgagagcatt
     3301 ctgtgattgg cagaactaat tgttctaaaa caagtttttc tagttctttg ggatgataat
     3361 tgttcagtgc ttttacataa atttgtttca tgttatcaaa gttttttgaa tctactccca
     3421 ataactgtcc taattgaacg agttcattga tcaagcggac cgaaactact tcccgactca
     3481 aaggattttt attttgtgca aacaatgcat caatcaattc atgtactaaa ttcttcactt
     3541 cctgatttcc agaacgaatg gcttcaaaca atcgattttg ttcttctatc ggatatctaa
     3601 taagtgtttt ttcatgagca gcaggaacga tttcctgata aaaaataatt gaacttggac
     3661 cagtatttac acgataatac agggcttctt ttgcccgatc aaccgattgc tcgctttcat
     3721 tcagcgtttc gaaccggtta ctgatgccta tactgatagt taaattcaag tattctttta
     3781 cacgtttttg aatgagtcgg caatactcca tgactttttt gcttgcttct gcatcatctt
     3841 tatccattcg ataaatagtg gcttgcattt cttcattcaa aacgatcggc agcattcgat
     3901 tttcctttgg cacaatttcc gtgatcatgt tgttgatcgc taaaagtagc aaatcacgct
     3961 ccccaccgtg actatcttct aacagatcga tttgaaccaa agctgtataa tagcagtcat
     4021 tttgagaact ataaccaaat tgctgcaacc gctgatctag ttctcgcctt tctactcgat
     4081 ttctaaataa actaagtaca aatagcgttt ccagctgtgg cttttgggta actaagtgtg
     4141 cacttaacgc ttctttttct cctatgatcc gactgactga ttgagcgacc aaatctagtt
     4201 ctttcccact gaatcctttt gatttaagat tcagacgttc ctgtatttga gaaatcggac
     4261 gggcaaatct gtccgaaaat aagtaggaaa gaagaccaat gagtcctacc agtgttaaag
     4321 acactgcaac tagcccgatt ctcagattgc ggatcattgc gccaattgca ctagagtcaa
     4381 cttctaatct gtaaatccaa ttattataat ctgatttcag tactatatac gttttatctt
     4441 tttctcttat cactttcagc tgattgtaat ctagatccac gtccgttaat acagttggtt
     4501 gctctttatt ttttactgtc tgagtagtaa aaaggttgcc aacttcgttt tcaatagaaa
     4561 gtatgtcttc tccactttca ccaacaactt gttctattgt atgtttctct atcgtagcaa
     4621 ttcccaatgc atatttttct ttttcaaaca ttggcaaaga aatcaccatt tcgattcctt
     4681 tgtttttctt ttgccaaaat aaattatttt tgttatttat gtacttctgt tgatactttt
     4741 caacttcctc ttcggtcagt tgactcaacg atccattgat tactccccat ttaccagcca
     4801 aactgactaa atcataatta ttatcatcca taacaatcgt ttctataaaa tttagttctt
     4861 tcctgatttc agaataagtg gagtaatctg tatatgtcag cggatgcttg aatatgtccg
     4921 agaaattttt ggtcgaacca tacgtagaaa acgaatattc aatcgttcta attttccatt
     4981 caacgttagt tttaacttgc ctgagcaaat tctttttgtc tgttaaataa ctcgattcga
     5041 tcgattcata ggtattctgg taaatgaata aactaaatcc tatgacaagt acggctccta
     5101 ataaaaacat cggtaaaaat attttataaa atactgtact tttcttcatt ttcttcctct
     5161 cctcctttta aaataaaagg ctttcatttt tctgtaaaat tgatactcat ctaattaaat
     5221 gagcattccc cgctttcaag aatagcataa ttaaaaataa aaatccaagt aatttttaac
     5281 gtgtgcaatc ttttcatatc aaagatctat tgacttatcg tagttatcgt aatatgatga
     5341 atgcgttaac aaaaagtgaa aaagtaagga aaatgatgga atggtaacga tcaaagatat
     5401 cgctaaagca gctggcgttt ctcatacgac agtttctcgt gctttgaata acagcagttt
     5461 aataaaaaat gaaacaaaac aaaaaatacg acaactagct aaggaaatga attattcgcc
     5521 aaactatagt gcaaaaggtt tagtgaatca aaaaaaatat ctaatcggac tatttttctc
     5581 aagtttgcat aaaggaactt catcaaattt cctagcagat tccattgcag gcatccattc
     5641 agtattagac acaaattaca gtttatctgt tgaaagtatc gatgttgttg atttaacaga
     5701 aatcaacctg caacgctacg atggactgat cgttatgagt caaagtgatg atgatcagcc
     5761 tttcatcgac tatctcaaag aaaaagaatt tcctttcgtt gttgtcaatc gtcacatcaa
     5821 tgatccagcg gttatcaacg tcactgccga tgatgcggcc ggtgttatgc aggcagtaga
     5881 ttacggtatt ggatgcggac atacgaagat cgcttatatt ggcggaaaga aaaattttcg
     5941 ttcgacaaaa gaacgggaaa aaggggtatt gaaaagtcta aaaaaagcga gcatccctgt
     6001 caatccagcc tattttttaa caggagatta cagcttagaa agcggcctcc aaaacatgga
     6061 atacctatta tcactttctg acctgcctac tctggttttt tgcggcaacg acgacatagc
     6121 gattggtgca ttgagagctg tacatttagc tggcctccgt gttccccaga acatttctct
     6181 gatcgggttc gatgattctc cagtcgtctc ctatctcaat ccgccgctta ccaccgtacg
     6241 taagcctttg aaagaaatgt gtcaagaagg aacaaagctt ttactagatt tgatcgaagg
     6301 caggacgatc gaacaatcta aaattgagct ctccaccttg ttgatccttc gtgagtcgat
     6361 caattacttg taaactacaa gtaattttat ataaaaatgt taacgtgtgc ataacacaga
     6421 aaggaagttt atatgaaaaa actgacaaaa gaattagtga aaaaaaacga agcacctgta
     6481 aaagttcttc agtttggtga aggcaatttt atgcgtggat ttattgattg gcagattcag
     6541 cagctgaata accaacaatt gtttaaaggt aatgttgcaa tcattcaacc tttagaacaa
     6601 ggtcttggaa atatgatgaa ccagcaagat aatttatata cggtcatttt acaaggactc
     6661 agcaatggcg aaatcgttga tacttccgag attatcaccg tagtagaaca aatgatcaat
     6721 ccttatgatg aatgggatgc ttatctatct ctagcagaaa atgacgactt ggcctatatc
     6781 gtctccaata caacagaggc aggaatccaa ttcgtggaga ctgataattt aacagatact
     6841 cccccacaga gcttcccgga caaactgaca gcctttttat accgacgttt caaattaaac
     6901 aaagctggct ttaccatcat tccttgcgaa ctgattgaca gaaacggcga acgtctaaaa
     6961 gaaatcattt tacgctacgc agaaaaatgg gatttagaac ctgcttttgt tgagtggtta
     7021 gaaaaagaaa atgttttctg ttgtagttta gttgatcgca tcgtcccagg ttatcctcgc
     7081 gaagatgcag gtgttttcaa tcaacggcat aactatgaag atcaattgat ggtcaaagca
     7141 gaaccattca tgctttgggt gatcgaaggg cctaaagaat tggagaatca actaccattc
     7201 aaacaggctg gcttgaatgt catcatcaca gatgatatga ctccttatcg tgaacgtaag
     7261 gtgcatttgc ttaatggacc gcatacagcg atggtccctc ttgctttgtt ggcggaattg
     7321 gaaactgtag aagaagtaat gaaagatcct ttattctccg catatgttga tcagttattc
     7381 aatctagaat tgattcctat gctttcttta cctaaagatg aattagccat ttatgctgac
     7441 caaatcaaag aacgtttctt gaatcctttt gcccatcaca aattagaagc gatttcatta
     7501 aatagtgttt caaagttcag cacccgtctg cttccagtgt tcaagaagta tatcgaagaa
     7561 caaaatcagg taccaccgtt aatcactgtt tcactagctg cgctacttct tatgtatcga
     7621 ggcgatcaag taaagccaca tgatgatgaa aagacgataa gcgaatttac tgatgcttgg
     7681 tctgataatg gaacagctat tcctcgatta ttgcaaaacg ctgcgctttg gggagaagat
     7741 ttgtctcaaa taccgaatgt gacagataca gttcaagaaa tagctgcaaa gatcgatcaa
     7801 aaaggtgtcc ggtcagtatt acaagaaatg aaaggaacga tggtccatgc ttgaaaccct
     7861 gcaaccaaca atgaaattaa atcgacgaga cagtgtggtc gtcgcattaa cccctattcc
     7921 aaaacaaaca caactgacga ttgatcagca aacgatcacc actcttgaag atatcccgca
     7981 aggtcataag attgcattgg gtgatttgaa agctggagac aacgtgatca aatatggcta
     8041 tccaatcggt catgtgacga cagacgtaac tgccggtcaa tggctgcaca ctcataatgt
     8101 aaaaaccaat ctttctggtg aattggatta tcgatatgaa aaagatgtcc atccaagtca
     8161 ttaccttttt gagaaccgaa catttcaagg ttacttgcga aaaaatggaa aagtagggat
     8221 tcgtaatgat ttgtttttag tacctaccgt tgggtgtgtg aatggcattg ctgaactgat
     8281 cgtcaaacag ttcaaggaaa aacatccaga tctgggacag tttgaccata ttacgatttt
     8341 aaagcatcct tatggctgtt cgcagcttgg aaaagatcat caaaatactc gagaaatttt
     8401 agcggacgca gtaaatcatc ccaatgccgg aggagtttta gtatttggat taggttgtga
     8461 gaacaataca gttcctgaat tcaaaaaaat tttaggtgaa tatgatgaag aacgagtgaa
     8521 atttctagtg gctcaagatg tttacgatga gatcgaacaa ggtgtggctc tattagaaga
     8581 gcttttaaca gcggcggaaa atgaccagcg catatcagtc ccgctctcta agttgaatgt
     8641 cggtttgaaa tgcggcggtt ctgatggtct atcgggaata actgctaatc ctttacttgg
     8701 tgcattttct gactacttga ttgctcaagg aggcagcacg atcttaacag aagtgccaga
     8761 aatgtttggc gcagaacaag tattgatggc acgagcggaa aatgaagaag tttttgactc
     8821 aatcgttgac ttgatcaatg acttcaaaca gtatttcttg tcttacgggg aaccagttta
     8881 cgaaaaccca tctcctggta ataaagcagg tgggatcact acattagaag ataagtcttt
     8941 aggctgcacg caaaaatcag gaagctctcc tgtcgttgat gtgctacaat atggcgaaaa
     9001 aatcagaaaa ccagggctta gtttattgca agctcccggg aatgatcttg tagctgcctc
     9061 tgctcttgct tcatccgatt gccagttggt cttgtttacc acaggaagag ggactccgtt
     9121 tggctcatat gtcccaacgg tcaaggtatc tacgaataca actctttttg aacgcaaagg
     9181 tcattggatg gattttaatg caggcgtctt attagaacaa ccaatggaag taatcttaga
     9241 atcgtttgtt caaaaaatca tcgctgtagc tagtggagaa gaaacgaaaa atgaacaaaa
     9301 tgacgttcga gaaattgcca tttttaaaaa cggagtaaca ctttgatttt cataaaacag
     9361 tataaaaaga aagaaggaag atttatgttt ttatctgatg attttttatt aaaagacgat
     9421 tgggcgaaaa agctttacca ttcctacgca aaaaacatgc ccattattga ttatcactgt
     9481 cacttagatc caaaagaaat ttacgaaaac aacaatttca gcaatctgac agaagcttgg
     9541 ttaggaggcg atcattacaa atggcgcttg atgcgagctt gcggcgtgcc tgaagaaaaa
     9601 atcacaggaa atgcttctga ttttgaaaaa tttttagctt ggtgtcaaac cgtaccaaaa
     9661 attatcggaa atccgcttta cagttggtca catcttgaat tgaagcgttt cttcggtatt
     9721 gacttgttga taaatgaaga aaatgcagag aaaatttgga cacaagcaaa tgaaattttg
     9781 gcagctcctg attttcgccg tcgggaaatc gcaaaaaaat cgaatgtaga agtgatttgt
     9841 acaacagatg atcccgcaga cgacttgcac tatcatcagt tgcttgctca tgaagaacca
     9901 gatttgaagg ttctaccttc attccgtcca gataaagcac tcaatattga aaaagaagga
     9961 tttaatgcat gggtcacact actggaagaa gcagctgacc aaacgatcac cacctatcaa
    10021 gaactgatag aagtcttagg gcagcggata gaatacttcc atcaacatgg atgtcgtgtt
    10081 tccgaccacg ctttagacat cttacgctat aaagaagcgg atgaaacagt attagaagag
    10141 atttttcaaa aagcacgagc taacaaacta ttatcttcag atgaaatcga tgcttatcgt
    10201 acagaaacac tgatacattt gacccacttc tatcattctc ataattggac gatgcagctg
    10261 cacatccatg cttatcgtaa ctgtaataca caaatgttgg aaaaattagg gcccgatacc
    10321 ggctatgatg gaatgaatga tctttctttg actattcctc tgcaaaaatt attgaatcgt
    10381 gcagaagaaa cggatcagtt gccaaagacg atcctttatt cattgaatcc gaatgactat
    10441 cctgcgattt tagctttgat gggctgtttc caaaaagaac agaatggaaa actgcagtta
    10501 ggttctggat ggtggtacaa cgatactcga gctggtatgc gcgatcaatt gacacaattt
    10561 gctgatggta gtgctttggg gaattttgtc ggcatgctga cagattcaag aagtttcctg
    10621 tcctacacta gacatgaata tttccgtcgt gttctttgtg aatttttagg cgaaatggtc
    10681 atgcgaggag aagcacctga agatgaacaa cttttaggaa gtctagttca agcgattagt
    10741 tatacaaatg ctaaaaatta ctttggcttt tttgcctaat tgattaatag taacagtaac
    10801 gaatcaaaaa caggatagtg aaataacgga atccgtttat ccacgtttta gagaagaaga
    10861 cggaccaaat ttgctccgtc ttcttctctt gctgttctgc ttcattgcct ataaaccttt
    10921 atgaaagaag agataacatg cctactatcc atattgccgg tgattctact gcggcagaaa
    10981 aagatgaaaa caagcgtccc gagacaggtt ggggagaaaa aatctctgct tatttttcac
    11041 ccgagatcca gatcaataac caagcaaaga atggacgcag caccaaatca tttatccagg
    11101 aaggaaggtt agcccgtcta gcttcacagt ttcagccgaa tgatttctta tttgtacaat
    11161 ttggacataa cgaccagaaa atccaagaag aaagaggtac gcttcccttc ggtagctatt
    11221 taaaaaatct gcagatattt tttgaatgcg caaaaaaagc gaacgtccaa atggtcttac
    11281 tgacatctgt gacgcgacga gattacttag aaaacggaac attgaatcca gatatacttg
    11341 gagactatcc aaaagcaatg cgtgcatttg ctgagaaaca ccatattcct cttttagatg
    11401 tgttctcaag atcacaagaa ttgttccaga ccttctcaaa agaagagaca aaaaaattct
    11461 acctgcatct tatgcctgat acttgtaaaa attacccaga aggactaaaa gacaataccc
    11521 actttagtcc agaaggcgct gataaagttg cccgaataat tgttgaattg ataaaagaat
    11581 cccgtctgcc tcttgctaat tatttacaaa aaggagtttg agatgtttcc attaaattta
    11641 ggcatccgtg cccacgattt agatgttcga aatcgtgaag aaatcgttca aaaagtatca
    11701 cagcttcact tgtcccatat ccaatttgca ccacaaaaag catttcctga acaacttaaa
    11761 ttaactgaca tgacacttgg gagtgctgcc tattttggtg aatacttcca aaaaaacaat
    11821 atcgaacttt ccattttagg atgctatatc aacctatcca gcaaaaatca agaagttcgt
    11881 gcacaagcat tggcaacttt caaacagcaa attgctctgt gctctgccta tcaagccaag
    11941 atgattgcta cggaaaccgg tagtgtctct gtcggttaca caaaagaaaa ttttactgaa
    12001 gaagcttatc agatcgccag aaattctatc attgaattag tcgctcatgc agaaaatttt
    12061 ggcgtaactg ttgctgttga agcagggatc aatcatccaa tctataacta tcagttagct
    12121 aaacgtttaa tcgatgaagt agcttcacca aatttaaaaa tcattttaga ttgtgcgaat
    12181 ttgatgcata aagaaaatca tgctgatcag gaaaaagtga tccgaggtgc cttggacaat
    12241 ttacatggtt atattacagc gcttcatctc aaagactata tcatggaaaa tggaaagatc
    12301 cgcatggtac ctgttggcaa gggctgttta gatttccgcc cggtactgca ttatatcaaa
    12361 tatgagcgtc ctctaatgta cgccactctt gaagctactc ctgagattta tgttcctgaa
    12421 gcaatagaac acttgcagtt tatttaccaa gattgttaag gagaagatta tggaggaacg
    12481 aatacagaaa agttatcaaa aatatcatgc aaatgctttt cagacattgc tgcatcttta
    12541 tcagggaaat tattggcgtt ttgccatgtc aggactcttt tttattatca aacatcttcc
    12601 atcttggtta atgccgatcg ctattgccaa tgtaatcaat gcagcttcat cgaaagattc
    12661 ttctcagttg caggccattt atttcaacgc ttttttgatg gcttgtctga ttggtcaaaa
    12721 tatattgacg aattattttc atgtaaaata ccatagcact tcgatccgtc aagtagaagc
    12781 tggactaaga gcgaccctta tcaagaaaat ccaagaacta tctattcctt atcaaaaaga
    12841 attgcaatct ggacgaatcc agtcaaagat catccgtgat gtagaagcta tccaaacgtt
    12901 gtcctctcaa gtatttgtca gcggattaaa tatcgctgtc aatttattcg tagctttagg
    12961 tatcacgctt tataaaagtc ctgttgtttt catgtttttc ttattgactg ttcctctcgc
    13021 cgcattcgtt actctctttt tccgtaaaag gatcagacag tccaactcag acttcaggca
    13081 agaaatggaa gagacttctg caaaagtgat cgaagtgatc gaattagcac cgattgctcg
    13141 agctcatggg ttagaaaaac acgaaacaac tcgcttaaat aagcatttta ctcaaatcta
    13201 tgaaaaagga ttccacttag atatcctgca atctgttttc ggatcagtca gctgggctag
    13261 ttttcagata tttcagctga tttgtttgat tttcactggg atattagctt tacaagggcg
    13321 catccaaccc ggcgatgtcg tgatgtatca gacgtatttc acgacgatcg tcaattccgt
    13381 ttctggaatg atcacgctga ttcctacgat ttcaaaaggc atggaatcta tcacttctat
    13441 tggcgaactg ttgattgctg gcgatgtaga aacttatcac ggtaagaaaa aaatccaaca
    13501 tttggatgga aattttcgtt ttgaggatgt ttcttttctt tatccggact cactcaaacc
    13561 gattatcgat catttttctc tagaggtgaa agctggagaa acaattgctt ttgttgggcc
    13621 atctggctct ggaaaatcta cactccttaa cttattgatt ggatttatcc agccgacttc
    13681 aggaaaaatt tttctagatg atcagccttt ggatgaactg gatatgcgaa gtgtgcgaaa
    13741 ttatttagcc gttgttcctc aaaccacttt gttgttctcc gcttcgatca aagagaacat
    13801 cacttatggc ttgaaaaacg tatcaaaaga acgtttagat gaagtcatcg aagctgcgca
    13861 actttcttca ctgattgacc agcttcctga tggtctggat accttagtag gcgaacatgg
    13921 caacaagctg tctggtggcc aaaagcaacg tatctccatt gcacgagcgt tgatacgtca
    13981 gccaaaaatc attttgctag atgaagcaac ctcagcttta gataaccagt cagagaaaaa
    14041 aatccagcaa gccctgaatt acctgacaga aacacccact acttttattg tggctcatcg
    14101 gctttcaacg atcaaagagg cagataaaat cgttgtgatc gatgaaggaa aaattgttga
    14161 aataggtact tacgaaaaac tgttagctca aaaaggctat ttctaccgct tgaaaaatga
    14221 atgacaaaaa ataggagcta tgacaagact tttgtcgtag ctcctatttc tgaataaacg
    14281 gtgttctcct gccaactcct cggtcacaag tcacaatagt catcaaacat gagaagctgt
    14341 tttttgaaat tgttccttgt aactcagagt taaacggtag gctcacgacc tcttggtaaa
    14401 tggtgttcaa gagacagcct atcggcaata agaagcaatt ttgtcatcgc tcaaggccga
    14461 acgtctcttt cacaccctct gttgtttcat aaaatagttt tattcgctgt aaaggtcgcg
    14521 aactggtgtc atgatgatac ggttcaagtc attgatgatt gtactgaagc cttgctcttt
    14581 ttgcatcaag tcattgatta cttcttctga ttggattttc acagccattt cttgtgcttt
    14641 cattgcatct tcgtcgctga actcttgtcc actcatttgt ttttcttgta attcgatttg
    14701 catcgcttgg aagtctttga acagtttgtg tgcttcttcg tttgcttgta ctttctcgta
    14761 cgcttctttc aacgctttga attctggtaa ttcacggatc tcacgttcga tttgattcgc
    14821 gctatcgtag atgtttgaca tgttatgccc tcttttcttt tagtagttac tctctattgt
    14881 aacatggggt tattcgtttt caaaggggct actctccttg atatttccgc cagaggtctt
    14941 tagccgcttc accaattccc tgaacgcctt ctttcaccat atcgccgaag tttttcagcc
    15001 cttcttttgc ttgttcacca tattgattca agttatcttg ccaatttcca gactctccat
    15061 tagaatttcc tgtgtttcca acttgatctg cagctaccac ttgtcctcct gtggcatagg
    15121 catctgctac actaaatcct gtttttgaag tatacggaag gatgccttct gccgctgatt
    15181 tgaagacttt cccgacaaca tttccacttg tcccttccaa atagtgcagc ttgctggatt
    15241 cttcgtaacc catccatgtc gaaatcacta cgtctggcgt gtaaccgatc atccattggt
    15301 catttgcttt tgtggcatcg aaattagttt ctgtggttcc tgttttccct gctatcgtat
    15361 aacctgcagg attcgcagca gccgctgttc catttgaaaa tgtaccaaga agcatgctgg
    15421 tcatttcatc ggctgtttcc tttgatatga cctgttttgg ttttttgttt gtgttatcga
    15481 cgatcaccgc tccagtcgaa tcaacgattt tcgtgataag atgcggcgta tacatctgac
    15541 catcattggc aaatgcactg taagcacccg ccatgatcaa tggagatact cctttttcca
    15601 gtccaccaag ggctaagcca taatacttat cagattttgc taaaggcagg ccgaattctt
    15661 ctgctttatc atatcctttt tgtaaaccga tctcatgcaa aagccataca gcaggcaaat
    15721 tcaaactttg tgcaacagct tgatacatcg gtacttctcc ttggtatgtc ccgtcaaaat
    15781 tatgcgcatc gtaataactt tgcggttcgt ctttcaagat actggaaggc ttgtatccag
    15841 cttccagtgc tggtgtatat acgcttaatg gtttgatcgt tgatcctggt gaacgacgca
    15901 tctgtgtagc aaagctgaat cctctaaaga catgatctcc tcttcgtcct actagtgctt
    15961 gtacaccacc tgtattcgga tctaaagcta ctgaagcaga ttggaccatg gcaccatctg
    16021 aagcatttgc tgggaataat gcactgtttt gataagtagc ttctaattgc ttttgataat
    16081 cctgatctaa agctgtatag attttatagc ctttattcat gacatcttct tcatcaagac
    16141 catactcgtt aactgcttca tcgatcactg catcaaaata ataaggataa cgataaccag
    16201 aatctgaatt atcgtatgtg tcattaagat acgcgctgat atctgtctgg ctttctgctt
    16261 gttcttgttc ttttgtgatt tttccgtttt cttccattac acttagtact gtgtttttcc
    16321 gatcattcgc attttttggg tgatcgatcg gattataaat accaggacct ttcagcattc
    16381 ctgccaaagt agcagcctca gacagcgtaa cattcgttgc atctactcca aaatactttc
    16441 tggaagcgtc ttggacaccc cataccccgt tgccaaaata ggcattgtta agatacatgg
    16501 tcaagatttc ttctttgctg tacttctttt cgatctcgat tgccaaaaat aattccttcg
    16561 cttttcgatc aaacgtttgg tctaatgtca gatacgcatt tttggcaagc tgctgagtga
    16621 tcgtacttcc tccgccccct gatgttccgc cagacaagac cattcggact gctgcacggg
    16681 caatcccttt gatatcaaac ccgtgatgct cgtaaaaatt cctatcttct gtcgagatta
    16741 ctgcatcttg gatataggga gaaatcgcgt ttaattctac atatgttcct ttttgggcgt
    16801 acagtgtgcc agcttcttcg tttttcttat cataaatgac tgtcgattgg cttaatcctg
    16861 attttaacgt ttcgacattt gcttgttttg ctaaaataaa gaggtagata cttgtcacta
    16921 agacacagat caaaccaatc agcaaaatca atttgttcac atgatatttt ttccagatgc
    16981 gctttcgcca tcgatggaat tgtccgagat atggtctgat ccaacgccaa aaactgatca
    17041 aagcagcttt tatcttttct aaaatgcttt gaaaatccat ttgcttcttc tcctgtctat
    17101 ttgattcaat cgtcttattt taccatagtg aaagagtgtt ttcttcctgc ttaagttgta
    17161 gttcaatatg tttttttacg ttagtgcaag tagagtaaca taagaatgaa cagaaaaatg
    17221 taagtttttt cttaaatatg ttttaaaaat ggtacaatta gtctgcgatt gcactgaaag
    17281 gagtacactt gtgaaaatca cgatcacttt acctatgaac catcctgaaa caacaattcg
    17341 cgacttgctt gaaaaggaat ggttagttcc tagaaaggtt cgacactttt tgcgtatacg
    17401 taaaaacgtt tggatcaatc aacaacctgc tttgttccat catgaagtaa agggcaatga
    17461 ccagatcaca ttgttattcg aagaaacaga ttataattat caagaagttc aattaggaga
    17521 tgcgaagcac atccgtgttt tatatgaaga tgagcatttg attatagtgg ataagcctgc
    17581 aggaatgaag actcatccaa atgaaccgac agaaaacagt accttactca atcatttagc
    17641 tgcttatctc gacactaaac agcaacgacc ttacgttgtc caccgcttgg acaaagaaac
    17701 aagcggtgcc gttttatttg caaaaaatcc atttgtcttg ccgatacttg gaagaatgtt
    17761 ggaacaaaaa atgatctatc ggagatatca agccatcgta tggggagaaa ttgccaaaga
    17821 tatgaccatc accaataaaa ttggacgaga tcgccatgat cggagaaaaa gggtcgtaga
    17881 tgataaaaat ggtcagagcg ccttgacaca tgtcactgtc aacaaagtac tttctgaaca
    17941 aacacaagtc tattgtgttt tggaaaccgg acgtacacac cagatcagag ttcatttagc
    18001 tcataaggga catccgatcg ttggagaccc tctctaccaa aatagaacag ctgaacgact
    18061 gatgctccat gcattagaac tgcacatgat ccatccattt actcaagaaa aaatagtcgg
    18121 taaagcttta cctggattat gggaatagaa ataaaaaaga acagagtctt atcagcagat
    18181 aatgataaga ctctgttctt tttgtgtaat ttgtctgctt acttttgatg ttcgtgttct
    18241 gctaacagca aactaccgat aatcccactt tcattcggca gtccccaacg aacgatatat
    18301 tcacttactt gaggtgtttc catataacca cccatcaatt caacaaattg ctgacggatt
    18361 ttttgaagga gatgatcctg attcattacc ccaccgccta aaataatctt ttcaggtgct
    18421 aacgtcaacg tatagttgat cagtgcttga gcaatataat aagcctgaat agcccaaaca
    18481 ggatgatctt gcggcagatc ttgccctttg atccctgtgc gtgcctcaat agacggtcct
    18541 gctgctaatc cttctaaaca atctttatga taaggacaag taccttcata atggtcatct
    18601 ggatggcgtt tcacccaaat atgtcccatt tcaggatgtg cgatccctga aaaaatttct
    18661 tcattgatca cgacacctgc accgattcct gttcccacgg taaggtaaat acaactattt
    18721 tttccttgtg ctgctccttg cttcaattcc ccatatgcag cagcattgac atccgttgtc
    18781 caagcagcag gaatattgta gcgttccttg attgtgccaa gaaaatcgaa ttgtgcccac
    18841 ccttttttgg gagttgccaa aacgtatccg taattatctt ttgttttgtc gataccaatc
    18901 gggccgaatg agccaatccc gattcccttc aattcataac gatcaaaaaa ttcaaatacc
    18961 tgatccaatg tttcttctgg tgttgtggta gggatactta atttttctaa aatttctcca
    19021 ccatctgaaa ccgcacacac aaattttgtt ccgcctgctt ctattccgcc atacattcgt
    19081 tttcctcctc gaatccgatt gtccgaatct cataaggttg gattattggg acaaccgctt
    19141 gcttcgttgg ttcttcaagc agattcaata tgacagtttt tccattgtct ttagttattt
    19201 ccaatttttc taaatgacta gacatattga aacctcttac tactacttta tcactaaact
    19261 tgctgcgttt caaagctgta attgcaaacg tttcactttt tatcgttaaa tattgttgtt
    19321 ttgaaatcaa tgttccttca tgatgtttga tttgttgagt ggaaaaagga atctgtgctg
    19381 cgtatgcatg caaataagta gagaattttt cttctggtcc atgtagttca atgctgtaat
    19441 tgaaccgatg ctcacctaga cactgtgctt ctggtgttgg aaaatatccc caatcgccta
    19501 gttctcccac actgcgaagt agcgtcactg cgatttgtcc gtcttctgtt acttcatatt
    19561 cattcaaacc aaagtttccg actgttacac cgtactcttc atcatgaata ttgacaaatg
    19621 cttgctgatg ttgcggattc gtggggtttt cccaactttt agacacatgg tttgggcgct
    19681 tcaccacttc aaaaatacta tctgcttcgt gatgttccac atgtaacttt gtaggaaaca
    19741 agacacgtaa gcgatgatct ttcatctgat tgtcgagagt cgtttcaaag tcgatttttt
    19801 tactatcttt tctgattgtc atgattgttt ttatttgaag gattcgtttt tctttggatc
    19861 gttctgcttt tcgataacga aattccacaa ccatctgctg ttctttttct aaacgctcgt
    19921 ctgcagaaac agggatttcc atttcctgta gaatacttat ttttgctatt tccggtgtat
    19981 ctactaatac ttttacttca gagttttctt tgttactgga taggattggc tgatcacaga
    20041 aaggttgttt aaagatatac tcatttccta tatcgccgat atcttcaaaa atatgcagat
    20101 tattcaactt tcgtttgttt ttgcgatctt ccattgtaat ggtaccattt ttttcaatcg
    20161 tcaaatgtag agggccgttt tcgatgattc gtccactctg atgaatcatt gtttcctttt
    20221 cttctgcttt cgcttcccct tctacaagcg cgaatgtttc ccaagaaaat gctggcatgt
    20281 tttctaatgg taaagtcact ttgatcattc ttgccatata tggcacacgg aaacggtctt
    20341 tcggcaaatc ataaccaaat tggacagttt cttcagataa aatagctggt atagtggccc
    20401 cactttttgt ttctacatga tacttacgtt taggcaaatt ttctaactct tgatatagtt
    20461 gttcaggtat tccttcagcg aatctttttc tttctaattc gatggttatt tctgcttcac
    20521 cagttttatc cattcctgca gtatttacaa tgacaaatgg aaagctgtct tttgggaatc
    20581 cggtcgtatc gattgctgcg gtcagctgtt ctaaggaatc ttgtgcaaga tactttccaa
    20641 cttcatctgc tttttcaaaa cgaggtatca tttcccgatg gacagaatcg actgaacaac
    20701 cgcaaatact gtcgtgagga tgattttgca ttaatgtctt ccaagcataa tctaattgat
    20761 catggggata gtttccacta acttcataag ccatcgtcgc aagtggttct gtaatatttt
    20821 ctagctgtcg ctggaccttg gtattccatt gttttaagta aacccgagca gatgctgtat
    20881 tggctaaagt ataccagcca tccgtttctt gacttgtcaa ttctccttct actgagccta
    20941 agtcttctgg cacatctttt tgaactgctt ccagatagtc agtaaaatta gaatgaataa
    21001 actcgtaatc tggaaacagt tcatttgcga gatggattgc ttttgatata tctttttgta
    21061 ccggttgatg atcaacacca ttcatcatca ataagtggtt cgtagaggca tattgttctg
    21121 catccgctaa tttttgcttc caaaaggcaa gagctgcttc tttttctact ggaatctcat
    21181 tcccgttgct ataccaattg gcaaatagca gaccaaagat tgctgtttga tcaggtcctt
    21241 tccaccacat ctctgagtat tgggaagaat agttttctgc ttccaaaact tgattatcaa
    21301 agccaattgg ttttacacca cggccaaacg ctgctgctga aataccagct tgtttcatta
    21361 attgaggcgt ctgtcccata tttccaaatg tatcgggaaa atagcctaac atgacagggg
    21421 ttccccattt acggctttct tccatgccaa tcagcatatt tctcacgttc gattccgagc
    21481 tgataagaaa atcatcttgc aagatataaa atggtccaat tctcaatttt ccttcattga
    21541 ttgcttgttg gattgcctgt cttttttctg gccttacttg aagatagtca tctaaaataa
    21601 tcgtttgccc atccaaatga aaactgttga aggacggatc aacttcaaat agctctagta
    21661 gatcgtctat caattcaatc agtcgcatgt gatgctgttc gtaagccatg taccattcac
    21721 gatcccagtg gctatgagaa atgatatata ctttcttttt catttacgat acctcctact
    21781 tttctactct aatatcaaag taatccatga ctaattcgca aaacatcata tttgcccaag
    21841 aaaaccattc tctcgtataa ttttcaggat tgttcacatc gaatccttcg tgcataaggt
    21901 gtgttcctgc gtcagttgct acaagtaaat tcaatatccg ctctttttca gatttgtctg
    21961 acgttgtcat tccttccata gctaatgcaa tcggccaaac gtatttttct ggcgtatggg
    22021 aggatccaat tccttttgcg tactttcctt catagaaata tggattttct ttactcaaca
    22081 atgttcttct tgtttgcaga taatcttcct cttgttcaga acaatatccc aagtaaggtg
    22141 cggcgatcag attgggcaca ttactgtcat ccatgactgt ggcgtttccc attccatcta
    22201 cttcatatgc ataaatcgtt tgcccttttt gattaaccgt tcgtccgtga ttctgaatcc
    22261 cctcttggat ctctttcttc aatttctgtg tttgctgtac aatttcttta tcatcgagta
    22321 tcgtttgaaa aatttcttcc acataaccta acacgaccac cgcaaacata ttggatggta
    22381 ccagatatcc ataacggcaa gtatcatcgc taggacggaa accagaccat gtcattcctg
    22441 taaaagctgt ttttgcacct cgcccgtcat tgatcagcgt atcttctttt cttgtcgtgt
    22501 ctcgtacaaa tgtataagga gagtgttcat gatcttgctc tgttttgaac acgtccaaga
    22561 tttttttgat accttcaata aaagattgat tgaattgatc agtttttcct gtatttttgt
    22621 aaagaagata ggccaactgt attgggtagc ataaagaatc aatttcatat tttctttccc
    22681 agatccaatc gttcattttt gtatgatctg tttggtggcc agcaccgtta gcttcttcgt
    22741 tgaaggcatt cgcatatgga tcgatattga tataaaaaaa ttgctttttg actaacccgc
    22801 tgatcatgtc agctaattcc tcatcttctt ttgcaatcac taaataagga cgaacttgtg
    22861 cagtagagtc tcttaaccac atcgctggaa tgtctcccgt caataaaaag gtggttccgt
    22921 cattttgctt tttgactgtt gtcaacagag tattggcaaa tgctgctgta aaattctttg
    22981 cccagtccgc atggatatcc ccacattttt gtgtgatatc ttccataaat ttctgcaccg
    23041 attttggtat atctttataa gccactaata aaaccttctt tctatttgat atatctttaa
    23101 agattatact tcatacagcc aattatgtct acgctttcaa aaaatatctt tttatttact
    23161 ttttcatcca ttatggtatt atttgaatat gatatatcat taagaggtgt ttatatgaat
    23221 caaccattgt accagacaat atttaatgat ttgcaaacgg ctattttaac tggtgaatta
    23281 cctgtagaca gccaactacc aactgaaaaa gaactttcac gtacctataa agtaagcaga
    23341 atcacttcca aacgtgcatt gactgaatta gagcaattag gacttattta tcgcgttcgc
    23401 gggaaaggca gtttcgttaa atccgcttct ccggaacaga ttcttgcttc tcctacaaaa
    23461 acacgacgga ttctgtttct tcttccatat gtcgctgatt tgtctgttgg tgattttagc
    23521 aagggattga accctgtgat gcaagataaa cagattgatg tcatgatgac gacgcttgac
    23581 tttctacaaa ataaaacagc aaaagagcta atcaatgaat ttgacggatt gatttattat
    23641 gctcttgata cagaacaaca tcttgactta ctttttgagc tttcattgaa agaattccct
    23701 gtcgtcatat tagataaaaa aatctatgag ttaccttttc ctaccgttct ttccgataat
    23761 ttccaaggcg gtgcgcttgc tgcctcttat ttgatcgaac agggacattc aaaaatcgct
    23821 tatttgtttg gtacgcagac tcatccacaa tccgttcgac agcgttacct tggttacctt
    23881 gaagcattgg acaaagctgg tttgactttc cacacttcac tggatgacaa aagcgcgaca
    23941 ttagatgaat tgctttctta tatcactaag tatgaagtaa ctgcttttgt ttgtgaaaac
    24001 gatgttgtcg ctatccagac catgaatctc ttgagacagc atggttatca tatccctgaa
    24061 gatttttcaa ttatcggatt tgatgatatc caagcagcag ctcttgttga cccgccactg
    24121 acaaccatcg cacaagattt tgaacagtta ggtaagcttg cgggagatgc tttggtcact
    24181 tggttagaga caaaagatcg accatccgat agtaaatttc cagtttcatt catcaaaaga
    24241 caatcaacaa aggagaaata aaatgaatat cggtcaaata gatactagac atgcaacagc
    24301 gaatcagcca aatttctcta atgggaactg ccagccttat actggcgttc cttttgggat
    24361 gaattatttt gcaccgcaaa ctacggatca aaacggcagc tggtggtttc atcctgatga
    24421 ccgcgttttt caaggctacc gtcttaccca tcaaccaagt ccttggatgg gtgatttcag
    24481 tcatatgctg tttacgccga tcaatggaaa actacaggag aacacccttt tccatgctca
    24541 aagttcttac cgcccagaag aaagtatatt ttgcccgact catctgtcga tctgtcaatt
    24601 acgttatggc atctgttcta cattgatacc tagcatgtat ggcggaatct tatctattga
    24661 ttacagcaaa aatgacagcg gtttactttt atcctttccg ggacgccatc agctctttgt
    24721 tatagatcct tacacagtgg aaggaaaaat cacacatttt gctggttcag aagatcctga
    24781 tttttctttt tattttatat tgagatttga atatccttta acaattgatg agttagctgt
    24841 ttccaacaaa aatagcgact cgatcccgtt gtattttgaa cagacaaaaa aacaaactat
    24901 ccgatttggg acatctttta tcagctcgga acaagcagct tataacctgg aactagaaca
    24961 aaaccaaagc aaagagactt accttgctca cagtcaagaa caatggcagt cctattttga
    25021 tcgtatacag ctcacacacc atgatcaaca acaattgcgg acgttttatc ataatttata
    25081 tcgggtgttt ttatttccac aaacatttta tgaaattgat cctagtgggc aaaaaatcca
    25141 ctatgatacg actagtcgat ctataaaacc tggtgttctc tatacaaata atgggttttg
    25201 ggatacgtat aaaacggttt atcctcttta ttctttgatt gctgtagaaa aatacgaaga
    25261 aatgctggaa ggttttttga acagctatag agaaagtggc tatttgccaa aatggctgtc
    25321 tcctgatgaa cgtggactta tgcctgggac attgatcgat gcggtcattg cagatgctgc
    25381 tgtaaaagat atccgacgag acttgatgcc tgaatttcta acggcaatgg aaaaaggtgc
    25441 tacggttcaa agcaaacatc caaattatgg acgccaagga acagaagatt acttgacata
    25501 tggctatgtt cctaatcact accacgaatc agtcaatcac acattagact atgcttatag
    25561 cgatttttgt attagccaag ttgccaaggt actagaagaa gaggaaatga cgaagaaata
    25621 tcagcagcaa tcattgaact atcaaaatat ctttgactat gagtcaggat ttatgcgttc
    25681 aaaagataaa gatggcaagt tcagagaacc attttcagct aatcgttggg gacaagatta
    25741 tgcagaagga agtgcttggc aaagcagctt tgctgtttat cacgattttt caggactgat
    25801 cggaaaatat ggtggcagtg agagatataa agaaaaactc attgagctgt gcaatcagcc
    25861 cccaacgttt gacccaggag gatatggttt tgagatccac gaaatgagtg agatggccgc
    25921 gatagaattt ggacaattag ctatttcaaa ccagccaagt tttcactatc cttacttgtt
    25981 cagttatata ggacaacctg aaatggcaca gccactgctt aaacagttga tgactcagac
    26041 cttcgacgat tctccaatgg gttaccctgg agatgaggac aatggaagta tggccgcttg
    26101 gtatatcttc aatagtctgg gattttatcc tgtcacgcct ggaaccggtg aatatgttat
    26161 cggtatgcca ttaattgaca aggctgtttt gcttttgtca aatggaaagg aattgacgat
    26221 tgaagcaacg cctaatcggc cgcagcaaca atttatccat aaaatcaaac ggatggacaa
    26281 agaatatacg aaattatatt ttacccatca agatttgctg aaaggcggca cgatctctta
    26341 ccaattaggg atcatccctc accctaagaa atatcaagca aaagatttgc ctttttcctt
    26401 atcaaactat aattaacaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca
    26461 gccaagcaaa aatagatcct catatttttc gtttggttgg tcttattacc gcagatgcaa
    26521 gcttttgaac accgtttatt gagaggttgt gaaatcagcg ttctgacctg agtattagag
    26581 agacaaatgg caaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca
    26641 gctgattgaa caccgtttag tggagaggtc gtgaaaaagc tgtttagttt cgagtattaa
    26701 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
    26761 actggctttt gaactccgtt tatcgagagg tcatgaaaaa gctgccttgc ctcaagtaat
    26821 aagaacagcc caaaattaga tttctagaca attttttata agttatttca ttacattggc
    26881 tttttctttt atgattctcc actgttttct cggtactctt taggggatct gccgacgatt
    26941 ttcttgaata atttagagaa atacgtggtg ttgttgtagc caatctcact tgctatctca
    27001 ttgatgtttt gattactgtg caaaagcagt tgtttcgctt tttccatacg taaatggttc
    27061 aaataagctg aaaaactttt tttcgtttct tttttgaaca gctgtcctag atacatgaca
    27121 tttaaatgca ggttttctga cacttctttg agtgtaagtg gttcttgata atgctggtgc
    27181 aggattacga ttactttttc cacattgtca ctgtactttt tctgtctctg atgctttttg
    27241 atgaatgaca gaagtagctg ctgaagttct tgcaccgttt ttgcctgatg gattttttcg
    27301 attccttgta aatattcctc atcttccaga tcaatcaatt cccgttgaat ctccataaac
    27361 agtaaaaaac tggaatatcg tatatcttcc ggcatcatgg ctgctaactg aaactgttca
    27421 aaaaaatcag tgatcatttt ttgagcgact tccaattgtt tattttgcag cacgcgtctg
    27481 aaacttgaaa aatcgatggt ttgatctttt gtttctgctt gtactgcgta aaaaacatgc
    27541 tcgtctttat ctccataaaa ttgatgcaac tgtagattgt ctttcgcttg ttggaatgtt
    27601 tcagggattt tgtccaaaga atctgtctct tccccgatac tgatcagcca ttcctgatca
    27661 ggaaagtttt cttgaacaaa acaacagaag ccatcaactt catctgcctc caacaacaac
    27721 gtgatcaata cacggtctcc gtaatttcgt tgatagtaaa agatttgttg ccgttcttgc
    27781 aaccatctat tgataagagt atcatgagtt cttgccagtt gaatcaatac tatcctatgc
    27841 tgcttctcac ttatttgtcc tattatttct tcttcactta tttcatccaa ttcttcattc
    27901 aaccattgac tgaataacag ttcttgatag atttcttgtt gatttttttg ttcattttgc
    27961 tgatctaacc gtgttttgat tttcttgagg ctttcaacca attcgaactt attcacgggt
    28021 ttcatcaaat aattcacggc gcctaattgc atacctcctt tcaaataatc gaattcttgg
    28081 tatcctgata aaatcataaa ttcaaaatta tgacgttctt tttgagccgc ttcaataaat
    28141 tccagtccat ttatttctgg cattgtcaca tccgttacta ctaaatcaat ctgtcgctgt
    28201 tcaagtacag ctagtccttc tttggcattc tctgctgttg ctactatttg aaagcctaaa
    28261 ctttgccaat caattatctt ttttaaccca ttcaaaatca tgtattcatc atctaccaat
    28321 aacacttgat acacgctcat ccctccttga atgtaataga aacggtcagt ccacctgtct
    28381 cattattctc aagcgacata taataactgc tgccgaagct ggcacgtaaa cgttcattca
    28441 cgttttgcag accgatagaa ccgtgaagtt ccactttagg atgagacagt ttttcttcaa
    28501 tctgttttag ccgtttttca gtcatccctt ttccattatc tttgatgatg atccttaccc
    28561 gtttgccttc ctgcaagact ttgacactta gcgcattatc gaatcgagta aaatcaatac
    28621 cgtgtttaaa ataattttca actaatggct ggatcacaaa tttaggtact tcgatctttt
    28681 ccaaatcagg atcgatcata aaatgatagg ctactcgatt aggataacgc atttgataca
    28741 aatagacata tttttcgcaa aagtccagtt cttcttttaa agtgatcgtt ttctcttgat
    28801 tcgtattgtt tcgaagcaaa gcggaaaacg catacacaac atctgctaat tcttcacttc
    28861 cttcgctgat tgcatacatt cggatatatt ctaatgtatt atataaaaag tgtggattga
    28921 tctgtgcttg aagcgcccgc atatgtgcgt cttgctgttt gatttctaat ttgtagatgt
    28981 cttctacaaa ctgattgatg ctatccaaca tttcgttgat accgattgaa agttccttca
    29041 gttcatattc cgtgtttgtt atgtcgatcc gcgtctctaa attccctgct gctgtttgat
    29101 ccatggcctg catgacgata gatacttgct gtgaatatcg tttgaatgtt ttataaagaa
    29161 agataagcag tatattgtct aaaataatga taccaatgat cagcggggca agattttttc
    29221 ccgtttcgat ttttacactt tttttatcta gtacagctaa tatacgataa tcatcagaca
    29281 gttcttggtg ttgaacaaaa ttgttttttt ccagatcgtc aatcggcaat tgtgaatttt
    29341 tcttcagact ctctgtgatg atcatttctt gtctttcaaa cgtttcttta gctattttat
    29401 tatcatggaa tgtgtatagt cgatttgtcg ttccagaaat catgtataaa gagagtccat
    29461 tgaatgacgt tagattttct aaaatcatat ctagttcttt cttttgaaaa ccaataaaaa
    29521 tacttcctga ctcagctcct ccttgtgtga taggcaactt gatataaaag gcgtctagta
    29581 attttggtgt cccctttttt atttccccac ctttgttttc tctagaagat tcataatact
    29641 ccggtagttg attcaacacg atatatatcg cacttagttc ttcataattt gcgtagagat
    29701 ctttgatttg atttgggaaa gaaactaatt catcggtact gttttgctgt tcgtatacat
    29761 acatcagata ctgatctatg ggttttgtta agtaggtcgt cacattttcg atcttttcgg
    29821 aattccctac aagctggttt ttgatgatcc tactcaaggt tgttttatca ttcagcattc
    29881 tgcttgtgct ttgaacggca tcacttgtca tgttttctgc ctgtttttga ttttgttccc
    29941 aagtatggat actaaaaata acggtagcag tcatcgttac accgatcatg ataaccgcgt
    30001 atttccgcaa cagacgattt agtaaggttc cttttgaaaa tagaatccga aacttattca
    30061 taactttcca actgtttatc taattcttca cgccaatgtg ttgtcatcgt accattccaa
    30121 accgtcaaaa gaccaatgac accaaacagg atcaatcctt tgaattgcca agtcacgcct
    30181 aaaattatac cgctaccaat aattattttt agaaaagacg aaaagctgga aaaaaccgaa
    30241 ataaaactta gctttagcag attaggaaca gagatcgtat attcactatc taaaatcata
    30301 ctgtattgat aagtagcaaa taggcagagc aaggcaaaaa gtaaaataaa atcaatagct
    30361 aaaaaaatga gccctttgat ttgaacagat aaatataaat tgtaactcaa taaagcagta
    30421 ccagataaaa ataaactaaa tagcagattg cctcttaaaa aatttctttt atatatattc
    30481 cagcctcttt ttattgtgat ttctttatac tcgaatccgt acaaataaaa tagttcattg
    30541 actgttttcc atgccgcacc taatccaaag atgatcccgc cggcaaatgt atatatccag
    30601 aaatacaagg ttagttttat aatgacccag atccggataa ataactcttc caaaaccttc
    30661 cctaacatat cttctcctcc aaacattaag tttatacttt ctcattatac aaaaaaaggt
    30721 tgggcaatca gcaccttgac ctgattatta gagaaacaaa cggaaaaata gttcctcata
    30781 ttttgtcgtt ttgtgagcga ataccgaggg ttagctgatt gaacaccgtt taccaagagt
    30841 ttgtgaaata gccgcttagt ttcgagtagt aagaaaaatt ttgtgaatat ggctttccac
    30901 atttttacat atatttagct taataccgag aaactggctt ttgaacaccg tttattcgga
    30961 acaagaggtt gtgacacgtc ttttgtcaca acccctttgt ctttattcat tattattctt
    31021 gtcggaactc atcatattgt ttttgcattt ctttcaatac cttatcatag ccagccttgt
    31081 ccaaagcgtc tttcaatttc ggtaatgttt catctggatc aacagtccct gtattcaatc
    31141 catctaaata ttgattcatg acattagaaa tattacttaa ttctgttttg acactgtcag
    31201 tgttgaagct gaatcctaaa atcggtgaag tttctgcatc agcaatcgat tgatcacgtt
    31261 tggcaatcat gtcatccgta atagactctt gtgtatatag aatcttgttg tttcctgtat
    31321 tccaagcaga catatgtgta tttggctgat aaccatctag caatttgatt ttatcatctg
    31381 aaccatcgac tttttcccat gcttctccct cgatccccca aacaagccca ttcaataatt
    31441 ctggatcact gttaagcagc cctagaagtt ctactgattt ttctttattt tttgaagtat
    31501 ttgatacgac aaaatttgcc atttgtgctt gagctgtaga ttttagtgga acagtaattg
    31561 cttttgagac aagttcttgt tttgctgcat ttgtcaaaat tgtatcgcca taatcatacg
    31621 gtccttgtgt ttctccacgc attagccaag tatttccttc tagtggataa tccttattgc
    31681 tcgttgcagc gtcacttgga atgagtcctt gtttgtacca gctatgcatt gtacgtaaca
    31741 gtccgatata cgtttcatta tcgtattggt tgatgatttt cgaatcatct ccatccagat
    31801 caatagcaaa tggtaacgta ttccctaaag gataatcaaa gttcccttgg actttgaagc
    31861 cttgtccaat ggcaaaagct gccgtgtttg gttctttttc atggaattcc ttcaagactt
    31921 tttctgcatc agcgtaagat tggattccat caattgaaag atcgtattta tctagtaaag
    31981 ctttgttaaa agtaagtact tgttgagcaa agacatttcc attgactggg aaagcatata
    32041 attttccatt gaccagattt cctttaatat atgcttcatc taaatcatta taagcttttt
    32101 cagcgtactt aggcgctaat tcagtcaaat cagcaaaggc tcctttttgg gcattggaaa
    32161 catagttgtt cgcaaaggcg atatcataat tttccccgga agaaatgatg acgttcattt
    32221 tcttttcgta atcgccccag ccaatgtaat tgatattgac ttttacaccg atctcttttt
    32281 cgattcgttt gtttgctact tccatcaatt gatcgaaatt atctggttta tctccgattt
    32341 gatacatctg caaagtgtcc gaattgctag cttctgcctg gtctttagaa ccagaacctc
    32401 cgcatgctgc taatgttccc aacaacaacg ctgaaacacc tgtaaaggct agtttcttcc
    32461 ataacttcat ttttcttcct cctaatttta tgatttatat ttttgtttct ttattctttt
    32521 actccgccga ttgttagacc tttgacaaaa tgcttctgga aaaatggata gctgatcgca
    32581 ataggcaacg tcgagatgac tacgatcgcc attctggcag attctcctgg aactgaggct
    32641 aatccgcctg tcaattggct tcctgctcct gaattttgtg tcagatattg aatattactt
    32701 tggattttca tcaaaagata ctgtagtgga actagcttat catcttggat gtatagtaaa
    32761 gcattgaacc agtcattcca gtaacccaat gcggcaaata aactgattgt cgcaatacct
    32821 ggaacagcta acggtaaaac gatctgaaca aatattcgca gttcgctagc tccatcgatc
    32881 cgtgccgatt caataatcga atcagagacc gaacgtttaa agaatgtgcg catcacaata
    32941 atattgaagg gactgacagc cattggcaag atcaatgccc aaatcgtatc ttttaactga
    33001 agaagatttg tcataacaag ataattggcc accatccctg gtgagaacaa catcgtaatc
    33061 aaacaaaaaa cggtaaaaaa acgacggaat ggaaagtttg accgtgaaat cgcataagca
    33121 tataaagaag tagccgtgct attgatcagt gtacctaaaa cagtaacaag tacagtgacg
    33181 aaaagcgctt ggaaaatttt atcctgcatc tggtcgaaca agtacgtata accaaatata
    33241 ctgaactttt ctggccaaaa actgtacccg tgagtcgaca atatggactc atcggtaaaa
    33301 gagatggcga taacaaatat aaatggcaaa atacaggaaa tagcaaagag tgcaatcatt
    33361 atattagaga aaaaattagc cgtcttattg aaagagcgga cttggactct ctccactttc
    33421 ttttttttca tttttttcct ccttagaata atgcagaatc gctatcaaaa cgtcgggcga
    33481 tcgtatttgt gatcatcaac aagacaaagc cgacaactga ttggtaaagt cctgcagcag
    33541 ccgtcatacc aaaatctcct gtggatgtca ggccattgta gatatacgta tccaaaactt
    33601 gagtcacatc atataatgca ccggaattcc taggaatgtt ataaaacagg ccaaaatcag
    33661 ctcggaaaat gtttcctacg gctaaaatcg ttaaaatcgt cattagtgga ataagttgtg
    33721 gtatcgtcac atgtttgatc tgctgccatt tgctagctcc atcaaccata gcagcttcat
    33781 aataagtcgg atcgattccc ataacagatg caaagtaaat aatgctgtta taaccaatcc
    33841 ctttccatgt accaatgaac accaagataa acggccaata tttcggttca ttataccaat
    33901 tgacagcttc tcctccatgt ccagtgatcc actgattgaa tattcctttg tcaggactta
    33961 aaaaagcgta aacaaagtaa ctgataatga cccaagatag aaaataaggt agtaaggaca
    34021 tcgtttgata aactttaacg agtcgtttat ttctcaactc gctcataatg attgcaaata
    34081 cgactgagat cagcagattc aaaaggataa atgctacatt atataaaatt gtatttttag
    34141 tgatgagaaa tgcttgatcc gaagaaaata aaaatttgaa attttcccaa cccacccaag
    34201 gactttccct caagctagcc aagaacccat ctgctgaaat atgaaaattt ttgaatgcta
    34261 cgacattcgc cattacaggt atgtaaaaga aaaaaatcat ccaaagcata cccggtacag
    34321 ccatcaggac aagtgcttta taacgccata gattcataaa aaaatgattg aacccctttc
    34381 gttttttcat ctaaaaaccc ctttcgattc attcgcaacg taattatagc gctttcaata
    34441 atgagaataa ataaacaaag tatagggaaa atgaaacaaa gtataggaga ggttgtgaaa
    34501 tcagcgtttt ggcctgagta ttagagaaaa aaacgggaaa atagttcctc atattttgcc
    34561 gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaga ggttgtgaat
    34621 tcagcgtttt ggcctgagta ttagggagat cgtgtcctta ctatctaact ctgagtcaca
    34681 aggaacaatg gggactgtaa caaaagtctt gtcacagtcc cttattccga acaaacggtg
    34741 ttccagaagt agcttctacg gaaataagcc gaaatttcac aaaaaagcca tccgaaagtc
    34801 agacggacaa gtctgctttt cagatggcgc tacaactact ctgcttattc ttttagctat
    34861 ccattcaatt atttttctct cacttgttct agctcttctt tggtcatggg tcgatattgc
    34921 cctttattca aatctttagg cagccaaaat tttcccatac ggattctttt taaatataag
    34981 acttcttttc ctactgcttt gaccattcgc ttaacttggt gaaactttcc ttcatgcaaa
    35041 atcagacgga taattgaagt ttctgtctct tgatctactt gatcaatttg gagttttgcc
    35101 ggcaatgtct gctcatcgcc atcaataatc agtccttctg caaataaacg gatatcttct
    35161 tctgtcatta taccgctaac ctcagctaga tattctttct ccacatgttt tttaggtgat
    35221 agtaactgat gggcaaacac cccgtcattc gttaaaatca agaggccctc tgtgtcttta
    35281 tctaatcggc cgactggaaa aagatcttcc cgataatcct ggtcttccaa taaatcgatt
    35341 acggtttgat catgattatc ctgagtagca gaaatgactc ctgcaggttt atgcaaaatg
    35401 tagtaaaaat ctttttgata cgtaatgatt tctcctaaat aagtaaccgc atcttcgaat
    35461 tcatttactt gcgctttatc gcttttcacc acttgtccat tgacttcgat cgttcctttt
    35521 ttgattaatc ctttgacttc tttgcggctg ccaagtccca tatctgctaa aaacttatct
    35581 aaacgcatgc gtttccccca tttcaaaaga gcatcaatct agctcttctg attcacttat
    35641 tttattttta atttatgtcg taaacgcgct attcctggtc ctagtagtct ttctgccaag
    35701 cggattttca aagctaaata accatacact aaagccccta tacctgctac tacaagaatc
    35761 aacaatagag actggaattt gctatcttcg tttaaaaaag caccaaaaat catctttgtg
    35821 atccacgaag ccaaaagcat aatcaaggta agaataaaga tcagcaatgt cctgcgccag
    35881 acaaaacttg gtttaaagcg ggctacttca tggattctct ttaagatcaa ggtacaagac
    35941 acagcaaatc cgatcattgt cgccaataaa gggccgtata cttcaaataa acgaatggct
    36001 gggtattgaa gaaggagttt cactagaaac ccaataacca aataattaat tgccgccttg
    36061 ttttcaaaca ttccttgcag catgttggaa actagcatat atagtcctag gaagagtcct
    36121 acaaaacttg cttggatcag tacattactt cctagagaat ccggtgtata aaataatgta
    36181 tttagcggat aggcaagtaa cataacacca aatgtcgccg gaaacataaa aaatgaaaac
    36241 aactgtaaat ttccgcttgt caattttgcc agacctactc gatctttcaa cgtaacagct
    36301 tctgtaatca acggtaaccc agtagacgcg atcgatgttg ccaatgcaat aactaccatc
    36361 gtcaacttat ctggattggc actaaaaatc gaaaaaagat ccagtaactg tgcattggaa
    36421 tactcggtgg atgcagacat gatcttcata aaagtgaact gatcgactaa tttgaagatc
    36481 gttacccctg aacccacaat aataaacgga atcgcttctt taacggtatc taacaacaat
    36541 tccttcgttg caatatttat tttgttttcg ctgtagtgaa taaacgccga tgtatacgct
    36601 tgatgtttct tcaaaaaata caaaaggaca agaatacttg ctagcatacc gataaatgcc
    36661 gcgaaagttg attgcgtgac cgccgtcaca tagtcaccat ccatgacttt catgatgatg
    36721 aatgtagcca atagcatata aaaaatacgt gccacctgtt ctacaatctg cgacagcgca
    36781 taaggcatca tttcttgatt gccttgcaaa taccctcgta tcacactcat acaaggaaaa
    36841 accaatacag cgatactcaa agaacgcatc gttggaatca gttcttctcc gccaccagaa
    36901 gcatgagcta gccaaggaga ggcgatgtac atgaacaaag caaacaacag gcctaacccg
    36961 cccatcatct gtaatgcacg gataaataat cgtcgtgaag tgccatattc attcaatgaa
    37021 ttatagcgtg cagtttgttt tgcaatcgca gcaggtattc ctgctgtaga gatcagtaga
    37081 aacaatgcat atatattgta tcccatattg aataatccat tggcagcctt agcattttcg
    37141 cccatccaag cataccaggg aatgatatag acagcgccta gcaatcttga aatgatatta
    37201 ctggcggtca tccaagcaga gcctcgtgcc attttttctt gcggtgttaa ttgatctaat
    37261 gctggttttc tttgattatc catcggtcag attccaactt tctacaaaac attactatca
    37321 ttttaattgg taaaacagaa actggcaatc gattttatat aacttttata agaacaattg
    37381 tttttttgaa ttcggtttcg tttttttggt aaagtaaaga aatatacagc cttttatggc
    37441 taacatttat aggagatatc aatgacacaa gaaataaaaa aactacccgt tatattttta
    37501 ggtcttttct ttatcacagt tggattgaat tggttcttgc tccctcacga tatagcttcc
    37561 gccggagtgg gcgccatcgg acatttagtt gaaacggcct tttctatcca acgctcagtt
    37621 actgtttgga gcatcaatct tatgatgctg cttctagccg ctgtcctatt aggaaaatca
    37681 gtatttttta agactgtagc gggaagtctg ctttttcctg ttgttttaga gattgttcca
    37741 aaagtggaaa tgatctcctc acatttcttt tcactgattt caggaagtct tttgttcagt
    37801 cttggggttt acacattgta cacagtcggg gcctcaaatg gcggtataac gataccgccg
    37861 attattttcc acaaattttt tcggcttcca atgccgcaag gacttttact taccaatagt
    37921 cttatcgtct ttttgaatta ttatgttttt ggattgttgg agacactatt cgttctccta
    37981 tctattacag tcagttcatt gtttatgaaa atactcatcc gcttgtcccc tgtgtcaaga
    38041 aaatttgaat aaagctggat tttgtcatag cggaaacaaa cgatatatta aaaagagtgt
    38101 gctataataa accaagaaat tgaataaagc gagggatcaa tcaatgagct tctctttaga
    38161 agacatccgt catttactat taaaagaaaa tctattaaaa gaatttgttt caacaagagg
    38221 ctggcatctt gatgtaccag aaaaagctga atttcttcag ttaagttatg attcaagaaa
    38281 agctgatgct tctactttgt ttttctgtaa aggaatgaat ttcaaagaag aatatttgga
    38341 ttcagcaatc gaacagggta ttcaatatta tgtatcagaa caaccatacg aaaattcagc
    38401 agtaggaatc atcgtaacgg atatccgtaa agcaatggcg cttcttgcta tggcttttta
    38461 cgactatccg caaaataaat tgaaagtgat cggattcact ggaacaaaag gtaaaacaac
    38521 tgctgcgtac tttacaaaag caatcttgga tcacacaaca aataaaaaaa cagcattgct
    38581 ttctactatg aatacaacgt tagatggcaa aacatatttc aaatcccatt tgacaacgcc
    38641 tgagtcatta gatttatatc gtatgatgtc agaagcagtt gaaaatggta tgactcatct
    38701 agtgatggaa gtttcttcac aagcttacaa aacacaacgc gtatacggct tgactttaga
    38761 tgtcggaatc ttcttgaata tctcgcctga ccatatcagt ccgatcgaac atccgacatt
    38821 tgatgactat ttctattgca agcgacaatt gatcttgaat tcaaaaacag ttgttttaaa
    38881 tcatgaaagt gactattttg atttacttag ggaaacagcc gatctattcc agattccaac
    38941 gatcacttat ggtcgttcgg aagaaagcaa ttatcaagtg atccgttcag ataaaggtac
    39001 tcacggtttt actttatctt ctcatgaaga tcgcttagct atctgcgata ctgcttatga
    39061 tattttgctg gctggaggat tcaaccaaga aaatgcagcc agtgcgatca ttgccgcagc
    39121 actaacaggt gcctccagtc aagatgcaca agacggatta aaagaagctc gtgtaccagg
    39181 ccgaatggat caattgatcc aatccaatgg agcgcatgtc tatgtggact atgcacataa
    39241 ttatctaagc ttgaaaacat tgctgaaatt tgccaaaaat gaacatccag atggccgtgt
    39301 aattgttgta ttaggcagcc caggaaacaa agcaatctcc cgtcgacatg attttggaaa
    39361 agtgctatca gaaacagctg acatcgcctt tttgacggca gatgacccag catttgaaga
    39421 tccgaaaaaa atcgcggaag aaatcaatga agcaattact aatccagatt tgatcgttca
    39481 ttatgaaatg gatcgtcctg aagcgattcg acgcgcttta gcagaaagcg ctccgcaaga
    39541 ttcagtcgtt attgcgggaa aaggcgtgga tccctatcaa aaaatcaatg gtgtagatga
    39601 accttatgaa ggggattatg caatcgtgaa gcggttgatt gaagaataat ggtatttata
    39661 tactagtggt ttcccatttc taagaaaaaa agggactgtg attttttgtc acagttcctt
    39721 ttttcttaga aatcatttta acttttcact agctaattct gctgcctttt ctctttcttc
    39781 atttaataat ttattatcat agaatttgat aaatgggaac cagataatga atgcgatgat
    39841 tgcacaaatg actgctaaca cagcagcttt ccaatcacca ccactaccaa caaatgctcc
    39901 gatcccgact ggtgaaggcc acggcatctg tgcaagcatc ggtttgacga tttccagccg
    39961 aatggcaaaa taagcgagtg tagcagaagc catcggagct aagaaaaacg gaaccgctaa
    40021 atagggattg tagacgattg gcatcccgaa aatgattggt tcattgatat tgaataatcc
    40081 tggtacaagt gaggcttttc ctaacacttt cagctgatca gatttcgcga ggaatgcaat
    40141 aaagatgatc aatcctaaag tcgcacctga tccaccaacg gttacataag aactgttgaa
    40201 ttctcctgcc aacggataat ttgcgccttg tgcgttagct gccatattag ctaatacgat
    40261 cggggtcaag aaagaagtga tgatattcgc tccatggatc cctacgatcc acaatgcatg
    40321 gatcaagaaa taaatcacca tgacaccaag ccatgtattc gtcaactgcg taacaaaccc
    40381 aaatgggata gcaatcattt tgaagatatc cgttcctagt gcaactaata atccattgat
    40441 gatcatcacc acaaacgcaa tgacaaatgt tgggatcaga gcagtgaaag aacgagaaac
    40501 tcctggcgga acaacatctg gcatttttat gacccaattt ctcttgacac acatacaata
    40561 caattcgacc gcaataatcg acataataat agctgtaaag attcctgaag ttcctaaacg
    40621 ttcgacaaaa gagcccatcc taataccatt tactacagtt tctgtctcat tgatagaagc
    40681 aatcaagctg attttaccat cagtcatgat caattcaggg atacacataa agaatgcaaa
    40741 aacagatagt aatgcccccg tgagcggatt aacatttaat ttttgttcat ctcgttcaat
    40801 tgacgttaat tcataagcaa acacaatggc aaagtaaata gataaaatcc ccatcgtcat
    40861 tgtattgacg atcatgtaca agtcactaac tttgaaaaaa gttgcattaa aaaatccttc
    40921 taaaaatggg aacggtaatg gcaaaatatt taaaaccaaa aacatcgagc ctacaatcgt
    40981 gaaaggaata gaagccatcc ccgctgccat gacagcccga acgattttaa gttgcgcaat
    41041 tttccccata ggtcccatca ggtatttctg caaaaaatca aacattagtt attctccttt
    41101 cctaaatata acgctttttc atattgttta atacggatat actgttggtc ttggttgagt
    41161 gaaattttct ttaaacgata ctgtataaat gcactggcaa aaataccgct tacaacaaga
    41221 atgaaaacaa ataactgtcc tccattgtta tttgccataa aaggatacaa gaatgtaaat
    41281 cctgaggtaa acaacactgg aatcactaat aaattaaaga cactctggaa caaaaaatac
    41341 cactttgtcc atggaacgtt cgtttggtgt tttcgataaa gctttacttg ttctcctact
    41401 gcaggcaaaa tagctaaaat cagaatcatc ggtaaactac ttcctaaact tttagctgat
    41461 agaagcagaa tcatccattg catgttcatg aaaaagaaaa aggcagtcag gtaacgtacg
    41521 attagataac gattgaaata catgtttttc aaactaagtt gctttttttc taattcgatt
    41581 ttccttttta ctgtatcctg cacaatgatc cttcctttct atttattttt ttgatacaaa
    41641 taattcattt cctgtgcaac ttccaataat gtcatcgtcg tcatcagatg atcttgtgca
    41701 tggaccatga taatttccat ttctattttt gtcccgctgg catattcttt cagaagttga
    41761 gtttgtgact gatgcgcatg aagaatctct tcatttgctt gtcgcaactt ctcttctact
    41821 tcttcaaaca tctctttacg catcgagcga aatgcttcat gtatcagtgt ccgtgcattt
    41881 ccgctatgga aaatgatatc aaaagaagtc acttgtagtg tttcactgtt tattttttca
    41941 gccatctgtt ttcctcctta ttcgatcagt ttgataaatt tactgctgaa attctcaaaa
    42001 ataggttcag ctaagatttc ctgctgtact tttagctggt caactaacct aacgattgct
    42061 ttagtcacga ccgtaattcc ttcattttcg acataagaag gcgaaactaa aaaaacaaaa
    42121 tgaatttctt gatattgatc ccactgcatc ccagaaggaa tcaatgcaac ggctaccttt
    42181 gtttcgattc caactggaac agcgggatgt gggactgcca ctgtatcact gaatatgatt
    42241 tgtcccatat tttcacgttg ctggatctgc tttcgcattt ctcttatata tccttcttct
    42301 tcatttatgc tcagcttttg cagcaaatca tgaagaattt cttccttttt cggttcgtac
    42361 gtataagtct tgaaaaattt ttcagacaac tgttcggtgt aaatctgctt tttttgctgt
    42421 agagaaaatg ctggtatcgg tctatctgag gaatgatagg gtatagattc tccaactacc
    42481 tttcgtattt tacgaacatc atcttcattc aaaaaaatac tgacatgtaa aactggaatt
    42541 ttgaaaaaca ttgtcgaaag atcaatagaa gaaataatca ggtcgattcc ttttaaagtt
    42601 gtttcattga tctcataata gccttttaca cttaccactg taatattttt accgaattca
    42661 ctgactacgc gattctttaa tagttgggca ctgccgtaac ccgttgcaca gataatcaat
    42721 gcatgtagtt tatgcgcagc tctttctttt tccaatgccg ccatgagatg caaagccaaa
    42781 taggcccatt catcttcatt gatggtatag tttttcaaag ccggcatgtt gctgaaatgc
    42841 ctttttactg cgtcaaagac tttgggattt tctttcttta tctcctcagt caatgggttc
    42901 tcaatgcgaa tacctcggct caatcgaatc atcatcggtg acaaatgatc gagtagtcca
    42961 ttgaaaagct ggagatcctc tactaatgaa aaatgaaatt cctgagacaa tcttttcaga
    43021 actttcgcta attcctttga tagttcctga tcattttgat tttctttgtg attcgactta
    43081 gccatgagat gtaatgtcaa ataagcaatt tcttcttcgg gaaacgatac acctgcgatt
    43141 acctcaatac gttgaacgat ccgctgcgcc acttgatact ctactcgctt agaaacttct
    43201 tgttcgatgc ctaattcctt gatttcaaac ccttctcgga gccgtttgat ccccaaagcc
    43261 aagtgtaaag tcagattctg tatgataaaa tccgaaactt ttaacttagc ttctcttgtt
    43321 tcatcgagaa tgataatgac tagctcttca aaactgatgt ctgggaaaaa acggctttgc
    43381 cctaaatatt ctttcaatga atttccataa tggtttccaa aaaaagtatc catgataaaa
    43441 tgccgtcgat ttctttcttc cccttcgatc catgtccctt gaccatgctt agaaacgatt
    43501 tttagtgaat atggaatcaa tcgctccttg atttcttgca tgtcctttgt caaactggaa
    43561 cgactgatat aaagctcttc tgccaaatca tccataaaaa gaatggcatc ttccaaaagc
    43621 aattggttca atatatactt ttgtcgatct tcggactcat aaaatccttg cggttctcta
    43681 gcatatccag gtactatttc ttgccgactc aaaaacaagt caaatgtcag tctttgtaaa
    43741 atatgcagtt ggtagccata acctggttta gcaatgatct tacctccgtt tttttctact
    43801 aactctttga tccgctgcaa gtaattacgg attgtccgat cagataataa caattcagaa
    43861 gctaaacgtt gactggtgac atactccttc ttgtgatcaa tcaaatatct caacagcaat
    43921 ttttccttct gtttcattat catccactcc tattccatca tatgttctct tcgatcacct
    43981 ctgctaactt ctggatgcct gtagggattg ggacatacgc ttggaaaggg atactaacaa
    44041 caggctttcc aacagattct cctaattttt tgaatttatc caaaaacatc gtcgtttgcg
    44101 ggctgatcag aaataaatca aaatcactat tcttaatcat attatcgcct tctgtagctg
    44161 aaactgcatc tacgagtacc tcttctcttt tttgcttaaa gaaatccgtt gtctttgagg
    44221 ccatcatcga ggatgacatt cctgccgcac aaataatcaa tgcttttttc ataaatcaat
    44281 cactcctttt atttttataa accaagcata tcttgtaagc gttttctatt caaaatatat
    44341 atttccgtag cattgcggaa aaaatgtgta tcatatcttg aataataatt tctggcaccg
    44401 tgatatacta gtgatagaat tttttcagga ggggatttag tgagtatcac agtgaatatt
    44461 ttgtatacaa gtacaaatgg acaagccaga aaatttgcag aagaaatggt cgaaagaaac
    44521 attgtcaaag cgattcgtgc agaagaagga aacgagaaat atgactatta ctttccacta
    44581 gaagatccag aatctctttt actgatcgac cgttggaaag atgaagaagc aatcgaaaag
    44641 catcacaaat ccgaaatgat ggctcaaata aacgaactcc gtaaaaagta taaattaaaa
    44701 atgaaagtcg aacgtttcac tgatttaccg taaaaagata cacatggaat gatagcaatt
    44761 tatcatccat gtgtatcttc actttttcct tattttttat tcgatctcat ctaatgattc
    44821 aaaccgtgtt tttctcttat ttttcggata agtatttcag tcaccccaat atacatgatt
    44881 cctaaacata ccccaaggat attctcaaaa atgcggatcg ttactgctcc tggaaccccg
    44941 aataaactgg cagtgattgc caaagcacca aaagaattaa aaactgtttt atatctatag
    45001 gtagaacaaa cacctaaagc tagaccacct aatataccga cccagttaaa aggaataaat
    45061 tggctgatac caataaataa aacacatcca atcaatgagc caatgattcg gtctactgct
    45121 cgttctttga aaccaatcga catcaatcca tagctagata caatagaaga aaatgcaaac
    45181 cctgcccaca tcaatcgctg aaaagggaca tactctcctg caacgatcaa aagactaatg
    45241 ccaaatgcat agatgagcat ccaaattttt tcctgcgaat acatgccttt caaaaaaatc
    45301 tctttaaaca agcttttgtc tttgttcttt tctcgatgtt ttctgtaaag gagaactgaa
    45361 aaccaacaaa aaaacaaaaa taataagcta cttgtttgtg taaagaaatt cttgttcaac
    45421 gaatctttag gtaacgaata aacaataaag agatatgaaa agccgtacaa agaagcattc
    45481 cccattttgg gatcactagc ggttgccatt aatatgctgc ttagtaaaat aaaatgaatc
    45541 aacatgccca taactgacca tttgatcagc tggacatacg gtgctactaa tagtgagaac
    45601 atgacgattg ctaaacctat gatcgaatgg gaaatcttat aaccaaagtc aacaaaacga
    45661 atactcatca acatacagaa taaaaccaca gcgtatggtt tatgcttcga ttcaaataat
    45721 gttgtaatta taatgataaa acaaatggca aacaatacga tgaataatga tcgtaaaaac
    45781 aatgaacaaa tatacatgca cttttctttt ttagaagctg cttctcgtat tttttgtttt
    45841 aaaataaacg gatctagttg tagagactga taaaaatcca cctgttgtcg tcctttcttt
    45901 ttacttttat tttttacagt catctatgac aggttgtaaa tactatggaa catcatatgg
    45961 cgttgtcatt ttcttgtcaa ctatttttcc tattcatgtt tttataaaaa aacatatcgt
    46021 tttcttgtat gattaaatca ccacaaaata aacaactgag agaacgatat gctttatgaa
    46081 tggttctatc aaaaaaattc tgagatcaat agacaaaaat ttgatgatta cagaggtctc
    46141 ttacgaaacc ttacagaaga aaaaaacatt gatcgttgct gcagttctct tccctgctcc
    46201 atgtgtctgt agaaattgtg gttctgctgt ggtagatgga aataggaaat taatggtggt
    46261 gaaaaacaag aagaaggaaa ccattgtcca ctttgaataa tataatcata tgccaatggt
    46321 tatacgccta aaaaagcagc gctatacctg taaaaactgt cgaagccatt ggaacgctca
    46381 aagttatttt atccgtccaa ggcactcgat ttcaaatcat gtcagacata aaatcacttc
    46441 tttactgact gaaaaagtgt cgttattttt tatttcgaaa agttgttagg tatctttgac
    46501 aaccgttatt cgcacattga aagagttgag aagctattta ccaaagtctt ccaaaagaat
    46561 tctgtcttga gtgttgaggg ttgtgaattt cgttctcacg tttccgttga ggataaactg
    46621 agttttattt ccgcggatgg cgagacagaa aaattaatcg agaaaattta cctacacaaa
    46681 aaattcctcg attaacaaac tatttcctta gctgcactaa tcctaaagaa atagaattct
    46741 tagttacaga catgaacgcc acctactttc agctcaccaa acatgttcta ccaaatgcga
    46801 aattggtgat tgatcgatta cttggttttt ccacgccttt caaggaggcg taacctttat
    46861 tcacgagttg gttgaagctt tccgagacaa aagacccgac ttgtttttct ccttattgac
    46921 aaagagccat taaaactaga gaaaaaatta caactgatcg ctgattattt gtagaaagaa
    46981 aatcaaagta ttacccaata aacttgagtc attaggcaaa aaacactgcg aaactcaaga
    47041 atgattttcg cagtgttttt gtatattttt tattaactag tattactaca aaggtttatt
    47101 tttcacttct caacgcagca caaaattgtc tttacttatt tactggttgg gttcaacctt
    47161 ctctactccg atactaatat ttgtttgtat accccttcta aaatcggtag tttccattca
    47221 attgatgggt actagttgat tttaaaaact atgcttattc aattttttat tttagctcat
    47281 atatttcgtt tctttctaaa ttttatactg atgaaaacaa gtagcacacc caatattgac
    47341 aatataaact ggctaatgat ggtttctcca gtttttggaa gatgcttatt tccactgctt
    47401 gttggattgt ttcctcttat atctgagcta tcagcaactt ttctattctc ttttgttaaa
    47461 aagatcgcca cttcttgttc tttttcgatc ttgaaagtta ctggtgtcgc atccaattca
    47521 taccccgttg gcgcttgagt ttctaccagc tgatatgctc ctggtgctaa gccatctatc
    47581 gccagttttc catctgctcc tgtggttaga cctgactgca gaacggttcc attggcatct
    47641 tgtaactcaa aaacagctcc ttgcaggact tctccgcttt ggtcatcgat ctttgtcaac
    47701 acgacaccgc ctggtgtaag tcgattttct ttcgtcaatt ctaccaccgc tgtctgactt
    47761 ctttcgatct caaactcgat tggtgtcgca tccaattcat accccgttgg cgcttgggtt
    47821 tctaccagct gatacactcc tggtgctaag ccgtcaatcg ccagttttcc atctgctcct
    47881 gtggttagac ctgactgcag aacggttcca ttggcatctt gtaactcaaa aacagctcct
    47941 tgcaggactt ccccgctttg gtcatcgatc tttgtcaaca cgacaccgcc tggtgtaagt
    48001 cggtttgctt tcgtcaattc taccaccgct gtctgacttc tttcgatctc aaactcgatc
    48061 ggtgtcgcat ctaattcata ccccgttggc gcttgagttt ctaccagctg atatg
//
LOCUS       DADVXB010000004        47272 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.004, whole genome shotgun sequence.
ACCESSION   DADVXB010000004 DADVXB010000000
VERSION     DADVXB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.004"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            35..1105
                     /locus_tag="KB902_000139"
     CDS             35..1105
                     /locus_tag="KB902_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6806998.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            1120..1788
                     /locus_tag="KB902_000140"
     CDS             1120..1788
                     /locus_tag="KB902_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6806999.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            1808..2386
                     /locus_tag="KB902_000141"
     CDS             1808..2386
                     /locus_tag="KB902_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6807000.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            2787..3698
                     /locus_tag="KB902_000142"
     CDS             2787..3698
                     /locus_tag="KB902_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6807001.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(4076..4993)
                     /locus_tag="KB902_000143"
     CDS             complement(4076..4993)
                     /locus_tag="KB902_000143"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBB6807002.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            5195..5632
                     /gene="zapA"
                     /locus_tag="KB902_000144"
     CDS             5195..5632
                     /gene="zapA"
                     /locus_tag="KB902_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBB6807003.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            5690..6238
                     /locus_tag="KB902_000145"
     CDS             5690..6238
                     /locus_tag="KB902_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBB6807004.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            6353..8713
                     /locus_tag="KB902_000146"
     CDS             6353..8713
                     /locus_tag="KB902_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBB6807005.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            8800..9114
                     /gene="trxA"
                     /locus_tag="KB902_000147"
     CDS             8800..9114
                     /gene="trxA"
                     /locus_tag="KB902_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBB6807006.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            9296..11074
                     /gene="uvrC"
                     /locus_tag="KB902_000148"
     CDS             9296..11074
                     /gene="uvrC"
                     /locus_tag="KB902_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBB6807007.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            11219..12118
                     /locus_tag="KB902_000149"
     CDS             11219..12118
                     /locus_tag="KB902_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807008.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            12111..13373
                     /locus_tag="KB902_000150"
     CDS             12111..13373
                     /locus_tag="KB902_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807009.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            13534..15432
                     /locus_tag="KB902_000151"
     CDS             13534..15432
                     /locus_tag="KB902_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBB6807010.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(15762..16481)
                     /locus_tag="KB902_000152"
     CDS             complement(15762..16481)
                     /locus_tag="KB902_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBB6807011.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            16818..17150
                     /locus_tag="KB902_000153"
     CDS             16818..17150
                     /locus_tag="KB902_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807012.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            17137..19140
                     /locus_tag="KB902_000154"
     CDS             17137..19140
                     /locus_tag="KB902_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBB6807013.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            19159..19629
                     /locus_tag="KB902_000155"
     CDS             19159..19629
                     /locus_tag="KB902_000155"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBB6807014.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            19650..20234
                     /locus_tag="KB902_000156"
     CDS             19650..20234
                     /locus_tag="KB902_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBB6807015.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            20249..21235
                     /locus_tag="KB902_000157"
     CDS             20249..21235
                     /locus_tag="KB902_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBB6807016.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            21225..21536
                     /locus_tag="KB902_000158"
     CDS             21225..21536
                     /locus_tag="KB902_000158"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBB6807017.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            21558..23339
                     /locus_tag="KB902_000159"
     CDS             21558..23339
                     /locus_tag="KB902_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBB6807018.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            23332..24708
                     /locus_tag="KB902_000160"
     CDS             23332..24708
                     /locus_tag="KB902_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBB6807019.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            24715..25350
                     /locus_tag="KB902_000161"
     CDS             24715..25350
                     /locus_tag="KB902_000161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBB6807020.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            25380..26735
                     /locus_tag="KB902_000162"
     CDS             25380..26735
                     /locus_tag="KB902_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBB6807021.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(26927..28321)
                     /locus_tag="KB902_000163"
     CDS             complement(26927..28321)
                     /locus_tag="KB902_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6807022.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            28413..29384
                     /locus_tag="KB902_000164"
     CDS             28413..29384
                     /locus_tag="KB902_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBB6807023.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINTISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            29381..30163
                     /locus_tag="KB902_000165"
     CDS             29381..30163
                     /locus_tag="KB902_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBB6807024.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(30332..30703)
                     /locus_tag="KB902_000166"
     CDS             complement(30332..30703)
                     /locus_tag="KB902_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6807025.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            30837..31280
                     /locus_tag="KB902_000167"
     CDS             30837..31280
                     /locus_tag="KB902_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBB6807026.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(31323..32132)
                     /gene="yidA"
                     /locus_tag="KB902_000168"
     CDS             complement(31323..32132)
                     /gene="yidA"
                     /locus_tag="KB902_000168"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBB6807027.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(32151..33518)
                     /locus_tag="KB902_000169"
     CDS             complement(32151..33518)
                     /locus_tag="KB902_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6807028.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(33502..34332)
                     /locus_tag="KB902_000170"
     CDS             complement(33502..34332)
                     /locus_tag="KB902_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBB6807029.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            34495..34932
                     /locus_tag="KB902_000171"
     CDS             34495..34932
                     /locus_tag="KB902_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBB6807030.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            35008..35628
                     /locus_tag="KB902_000172"
     CDS             35008..35628
                     /locus_tag="KB902_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBB6807031.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            35817..36323
                     /locus_tag="KB902_000173"
     CDS             35817..36323
                     /locus_tag="KB902_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBB6807032.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            36340..37239
                     /locus_tag="KB902_000174"
     CDS             36340..37239
                     /locus_tag="KB902_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBB6807033.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            37326..38210
                     /locus_tag="KB902_000175"
     CDS             37326..38210
                     /locus_tag="KB902_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6807034.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(38402..38473)
                     /locus_tag="KB902_000176"
     tRNA            complement(38402..38473)
                     /locus_tag="KB902_000176"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38438..38440),aa:Arg,seq:ccg)
     gene            38533..39867
                     /gene="rpoN"
                     /locus_tag="KB902_000177"
     CDS             38533..39867
                     /gene="rpoN"
                     /locus_tag="KB902_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBB6807035.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            40016..41107
                     /locus_tag="KB902_000178"
     CDS             40016..41107
                     /locus_tag="KB902_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBB6807036.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            41148..42149
                     /gene="gap"
                     /locus_tag="KB902_000179"
     CDS             41148..42149
                     /gene="gap"
                     /locus_tag="KB902_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6807037.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            42259..43449
                     /locus_tag="KB902_000180"
     CDS             42259..43449
                     /locus_tag="KB902_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBB6807038.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            43553..44308
                     /locus_tag="KB902_000181"
     CDS             43553..44308
                     /locus_tag="KB902_000181"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6807039.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            44424..45722
                     /gene="eno"
                     /locus_tag="KB902_000182"
     CDS             44424..45722
                     /gene="eno"
                     /locus_tag="KB902_000182"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBB6807040.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            46121..47260
                     /locus_tag="KB902_000183"
     CDS             46121..47260
                     /locus_tag="KB902_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBB6807041.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEKVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        15692 a         8194 c        10090 g        13296 t
ORIGIN      
        1 tgtataaaat gattatttca ggaggaggag ttaaatgttt ttagcattaa atgaaattat
       61 gcattcaaag ttacgttatg cgttagttgc aggggtgatg tttttgatcg cctacctggt
      121 attttttttg actgggttag cttatggctt agctcaagat aatcgaacag cagtcgacaa
      181 gtgggaggca gattcgattg tgctttcgaa agatgcaaat tcaaatctag ggatgtccat
      241 gattactaag aagatagcag aagaagtcga aggtgggaaa gtggcgtatc ttgcccaaac
      301 acctggagtc gtgactagta aagacagtac agaagaagga aaaatcaatg ttagcttctt
      361 cggtatcgat aaaaatcaat tcatcatgcc caatcttgtt gaaggaaaag cttttgataa
      421 cgatgatgag gcagtaggcg atattagttt gaaagaagaa tatggtctag ccataggaga
      481 tacagttaag ttatctggta gtgacaagac gtttaaacta actggcttta cggatcatgc
      541 caaattcaat gtctcaccag ttctctatac aaccatcaat gcttaccaag aaatccgctt
      601 cgaaaaagaa gatacaagtg aaaatgcacg gattaacgca atagttgtca gaggtaaaat
      661 cagtaattta cctgaagatt tagaacagat caaaatttct aaattcatca atgaattacc
      721 tggatataat gcgcaagtat tgacttttgg atttatgatc ggatttttga tcgttattgc
      781 ggctattgtg atcgggattt tcatttatgt actgacgatg caaaagatta atatctttgg
      841 tgtaatgaaa gcacaaggga tcacaggagg atttattgcg cgttctgtag tggcacaaac
      901 attcatttta tcatttgttg gtattcttct tggtctatta ggaacagtgg gaacatccct
      961 tgttctacct gatgcggttc cattccaaag caattggctg ttttttggcg tcattagctt
     1021 gttgatgtta gtagtagctg tgttaggcgc actattttct gttcggacaa tcgtaaaaat
     1081 cgatccgttg aaggcaattg gataagaagg aggaagaaca tgaaagcaat agaatttaaa
     1141 gaagtagaaa aaagtttcca agatggcgac caagtagtta aagcattgaa agaaacaacc
     1201 atgagtatcg ataaagggga atttgttgca atcatcggtc cttctggttc aggtaaaagt
     1261 acttttttga ctttggcagg cggattgcag acgcctagca gtggctctgt atttatcaat
     1321 gatcaagaat tcagtaatca aaaagaaagc gaacgcgtta aactacgttt taaagaaatt
     1381 ggctttattt tgcaagcttc caatctggtt ccttttctga cagtaaaaaa gcagttatta
     1441 ttagtagata agattaaaca tgaacatcgt caaaaagaag caaacgaatt atttgagcag
     1501 cttggcgtgg ataagttgat caacaagtat ccagaagaac tatctggtgg agaacggcaa
     1561 agggtcgcaa tcgctcgtgc attgtacaat gatccgtcca ttattctagc agatgaacca
     1621 actgctagtt tggattcaga aaaggcacga gaagtagtcg atatcttggc aaaagaatca
     1681 aaagacaaaa ataaagcaac gatcatggtt actcacgata cacggctgat tgacaaatgc
     1741 gatagaatat ttatgatgga agatggtgta ttgaaagaaa aagaataacc aaaaagcagg
     1801 tggaaaaatg gtccatcgat acaacaaaga tacacagcaa aaaattttga aagaagcgac
     1861 tgacttgttt atgtccaagg gatatctcgg cacttcaaca agagaaatcg cacaaaaagt
     1921 tgggatcacc cagcccaatc tctatcatta tttcggtgat aaagaaaaac tatatacggc
     1981 agttttagaa aaccacttaa aagatgttgg aaaagctttg agagaaatcg ttcaaacaag
     2041 cgaaacggga tttcaagtaa ccttgacaaa aatggcgcag tttttgattg agacacatct
     2101 ggtcgatttg tttctgatgc ttcacgatct tgaaagcaat ctttcaaagg aaacaagaga
     2161 tcatcttttc tttctatgga agaaaaatta tcgtgaacct tttgaagaaa tcttttcagc
     2221 aaaccaatct gtgctaagaa atgggatttc aaaagaaatc gcagcaaggc attttttctt
     2281 agtgttagca ccttacatca ctcggtcgaa aagacctgtg gaagaaccgc taaatgtggc
     2341 gcaattgatc gatttatatt tgaatggtgt attaggagaa gcgtaaagct gttatatagg
     2401 gagaaaatag ttaggtgaag aagcaagata tgacgaagat cgttatatct tgcttcttta
     2461 tataggtagt ttttcataaa tacaaatttg ttattctctc atgattatca gggtatattt
     2521 ttatttatta tgtcggtgtt ccaggaagtg ttttaattta ataacgaaga aattaattgt
     2581 ttgtagaatg aaggaaacta tttattgggt agatgaatca ccacgaatag tcaaaaggag
     2641 atttcaggat atgccaaaaa tgaaaaaaat cattttagca gtaatgttat tttctacggt
     2701 tatatctttt acagcccctt ttttgcttac ttaagctgat tttaagtttt ggcccttagt
     2761 ctggatctac gaggtgagag tcaagaatga aaaaaataat tggagctttt gtatttgcaa
     2821 tcattatcat tattatctgt tttcaaatag atgtttttgg tcaaaaaaag atagttggac
     2881 aaacggtcag cagtacgaac agtacggtta caaagacaaa ggaatcattt gatgatacag
     2941 aacaagagac attaatcaaa atcggaaaaa atgaccgtac actatataca gatgactcgc
     3001 taactacccc acttgcaact ataaacggcg gagagctggc ggagtttctt tctgaaacaa
     3061 aaaatgctta tcagatcaag acaaatgatg gctatactgg atatttagcc ctcgaagatg
     3121 gaaccaaagt cacaaagaat atacaaacaa aaccggaaga gctatctgat gcagtgattg
     3181 tattagatcc tgggcatggc ggaaatgata ctggggcatt aagcaatgat gaacaaacag
     3241 aagaaaaaga tataacatta agtacagcca taaaagtaaa aaaggcgcta gaggatgctg
     3301 gagcaacggt ttatttgacc catactacag atgaattagt acagcttgga gatatatgcg
     3361 actacagtga agaaaaaaag gcagatgtct ttatcagttt acacgcagac tctacggaat
     3421 atgcgaatga agcaactgga atcacgacat attattacta tggacaagag gaaacattag
     3481 cacagacaat tgctgactcc ttcactgatc tgcctctgga ttcaagagga atctccactg
     3541 ggaactatca agttcttcga gaaaatcttc aaccttctat tttaatcgag atgggttata
     3601 tgaataatga tagtgattta aaggaattag taacagacag ttatcagcag cagattgctg
     3661 caagtttgac acaagcattg accacttatt ttcagtaata aataagccca gccaaacaaa
     3721 aatagctcct catatttttc gtttggccgg gcttattatc gcagatgcaa gcttttaaac
     3781 accgtttaag gaagaggtcg tgagcctgcc gttcaactct gagtcacaag gagcaatttc
     3841 aaaaaacagc ttctcatgtt tgatgactat tgtgacttgt gaccgaggag ttggcatgag
     3901 aacaccgttt aagaaaaagg ttgtgaaatc aacgttttgt tctgagtatt agagaaacaa
     3961 acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg atcagatgat
     4021 tgaacaccgt ttattcggaa caagggactg tgacatgact tttgtcacag ttccattatt
     4081 tttttagtag cttcaaagct ttttctgtat tggcaaaatg aagtttggca tatttttcaa
     4141 gcataggcat gccgcctttc tccaatagtt ttgccgctac ttggtcagat ttcgttccag
     4201 ctcctgacgg aagggtgatt ccagcttcag ctgatgcttt gtctaactct tccaaaaagc
     4261 tggcacgact gatgatagaa gcagcagcaa cagctaaatg atattgttct cctttagtaa
     4321 cgaagtacag tttttcttgt aattgatttt tttctaaacg cgcatatttt ttaaaatttg
     4381 cttccggcgt aaactgatcg atcaaaatcg cttctggttt ttctggctcg atttttttta
     4441 gcagcaaatg gatcgcttga ttgtgcaaag cgactttcat ccgaacggca ttgtattttg
     4501 gttggatctc attgtatttt tctggagata agacaagcag tttatagggg atggtttttt
     4561 ttaagatgtc agcaagctgg atgatttggc tatcttttaa ctcttttgaa tctctaacac
     4621 caagtttacg taattctgca agctgatcac gtttcacata agcagcacat actgttagcg
     4681 gaccgaaata gctgccattt ccgacctcat cactacctaa aacggataat tgactgatat
     4741 tttttggcaa agaagaggct gtttttgctg gcttggcttg tttatcctgt gcctcccccc
     4801 atttatcagc ttctattgct gcattcgtac cttgaaacat cacttttccg gatgtataag
     4861 cggtaatggt cgtcccgtct ttttttgcag caaagctagt ataaggaatc tgtttattta
     4921 acaaataaga gcgatagtat gctttcattt gactaagttg gtcgtttgtt gctttgataa
     4981 tgacgttgct cataaaattc tcctcgtttt tatacataaa actataccgc aactcacgac
     5041 ttttcgtttt ctaagagatt gcgagacata gcattttttt aaagtttatc atataatagt
     5101 taagtatgtg aaaaatattt gtggagaacg gtgaaagaac caacttcatg gtacactaaa
     5161 taaaactttc atcaaatagg aggaaatgat tcgtatggcg cacgaaaaaa cacgctacaa
     5221 agcggtgatt gccaaccaaa catatactat tatcggacgg gaaaccaagc atcatatgga
     5281 tatcgtaacg aagctgatca atgaacagtt agcagaattg aaacaattat caccacaaat
     5341 ggataatgaa caagcagcaa tcttgatggc tgtcaatgcg ctttcggatc aattgaagaa
     5401 acaagaaaga atattggagc tggaagaaga aacagcagaa ttaaagaaaa aaatgatcaa
     5461 atttacagag cttgaaaatc gtgtgaaacg cattgaagca atcgagaacg aagctcggga
     5521 agtattgaaa gaaaatggtc aagcagatca taccattaaa aatcatgtgg aagcacaaca
     5581 gattttaaac gagaaacgaa aaggacaaat taaacaaaaa tcttctaatt aagatccttt
     5641 tatcaaaata agaaaaattt aaaaaagtta gaagagaaag gaacgtagca tgctgagttt
     5701 gctgatttta tttttattgc taattgcgtt tttttctgga gcacgtcgcg ggtttgcttt
     5761 gcaaatcata ttcgcgattg gatatgtatt gtcatttatt gctgcccagc atttttacaa
     5821 accattagca agtcatttgg aattatacat tccataccca gctgtcaccc caacatcaaa
     5881 gttagcattt tttgatcagg tatttgcctt tcacctagat gaagcttttt atgcaggaac
     5941 tgcttttctg attattttgc taattggctg gctgcttacc cgatttgtgg gggtttttgt
     6001 ccatggattg acgtatgtgc cgatcttgag acaggtagac tggattgcag gaggcatcct
     6061 gtcactaatc atggcttacg ttactatatt tttgattttg cagttacttg cctttgttcc
     6121 attagatgtg gtccaaaatc aattcggcga gcatagtttc gctcgtttta tcgttgagag
     6181 aacgccattt cttaccaaca agatgtatga gctttgggta acgaatattt tgaattaagg
     6241 aaaatagtgc tggaaaatat ttcgtttttt gtacagagta gtttatttaa gaaggctgcg
     6301 tagcgtatgt ccggcacagc tcttttttca tagtgaaaga taaggtgata aaatgaataa
     6361 ccgaatcctt gaaacattgg aatttgaaaa agtcaaacag atggtcagac aatttgtagt
     6421 gactgcacaa ggaaaagaag aactggcaga attggtacca gtgagtgaga aacaaacgat
     6481 cacaaactgg cttcaagaaa ctgaggatgg attgaaagtg caacgtctgc gaggcgggat
     6541 ccctatacct aaaattgaaa atatccgtcc ccatatgaaa cggattgaga tcggagcaga
     6601 cttgaatgga gtggagcttg cacaagtttc cagagtattg tctacgacaa gcgaattgaa
     6661 tcgtttcatt gatgatcttt ctgacagtga aatcgaattt gcacgtttgt atatgtgggc
     6721 agatcagtta gtcacgatcc ctgttttgag ccgccgttta aaggaagcaa tcgatgaaga
     6781 cggacgcgtg actgatgacg cttctcctga gttaaagagc ataagacaga acattcggcg
     6841 aagtgaacaa gctgttcgtg aacagttaga tgggatcgtc cgtgggaaaa atgcaaagta
     6901 tttaagtgat gcgatcatca ccatgcgaaa tgaccgctac gttatcccag tcaaacaaga
     6961 ataccgcggt gtatttggcg gtgtagtcca cgatcaaagt gcttcaggtc agactttatt
     7021 tattgaacca aaacaagtgg tggatttgaa taatcgtttg cgtcaatacc aaatcgctga
     7081 acgaaatgag attcaacgta ttttaagtga actttctgct gaacttgttc cccatcgtca
     7141 agaaatcatc cacaatactt atgtgattgg taaaatggat ctgatgaatg caaaagcacg
     7201 atttggtaaa gaagtaaaag ccatcgtgcc gggaatcagt gaagacaatc atgtcgtctt
     7261 gaaacaagca agacatccac tgatcgatca ggaaaaagta gtttctaatg acatcacaat
     7321 cggaaaagac tatcaagcca tcgtcattac aggacctaac acaggtggga aaacgatcac
     7381 gttgaagact ttaggtctgt tacaactgat ggggcaagca ggattaccga ttcctgcagg
     7441 tgaagaaagt caaatcggta tttttgagga agtatttgcg gatataggag acgaacagtc
     7501 gattgagcaa agtctatcga ccttttcttc tcatatgacg aacactgtag atattttatc
     7561 aaaagtcaat gaaaaaagtc tggtattatt tgacgagctc ggtgcaggaa cagatccgca
     7621 agaaggtgct gctctagcaa tcgcaatctt agatgatctt ggtaaaaagt ctgcttatgt
     7681 gatggcaaca acgcattatc ctgaattgaa agtttatgga tataatcggg caaatacgat
     7741 taatgccagc atggagtttg atgtggatac attaagtcca acgtatcgtt tgctgattgg
     7801 cgttcctgga cgaagcaatg cgtttgaaat ctctagccga ttaggtcttg atacagaagt
     7861 tattgatgaa gcgaagcagt tgatgaatga tgagagccaa gatttaaacg aaatgatcac
     7921 agatttagag aatcgccgga aaatggcaga gaccgaatat ctggaaatgc gtcattttgt
     7981 ttctgaggca caagaacttc acgatgattt gaaagaagct tacagctatt tctttgaaga
     8041 acgtgaaaaa gaaatggaaa aagcaaagaa aaaagcaaat gaagtcgtgt cagaggcgga
     8101 agaaaaagca gaaaaaatca ttgctgatat tcgtaaaatg caacagcaga ttgggcaagg
     8161 aaatgtgaaa gagcatcagt tgatcgatgc aaagacccaa ttagcaaatc tacatcaaga
     8221 agaaactttg aagaaaaata aagtattgaa gaaggcgaaa gaacaaaaaa cgttgaaacc
     8281 gggagacgaa gtgttggtta cgacttacgg ccaaagaggg acgcttttac gtaaaaacgg
     8341 gaatcagtgg caagtagaaa tcggtatatt aaaaatgaat gtgtccgaag acgagctgac
     8401 gcctgttgct cctcaaaaag agccgacaca acgagttatc catgctgtac gatctgaatc
     8461 tagtagtcac gtgccgaatc aattggacct tcgaggaaaa cgatacgaag aagcgctaag
     8521 tgaggtagat caatatttgg attctgccat tctagctggt tatcctcaag tgactattgt
     8581 ccacggaaaa ggaacaggcg cacttcgcaa gggaattact gattatctta aaaaccatcg
     8641 gagcgtcaaa agctttgagt ttgcaccggc aaaccaaggc ggaaatggtg cgacaattgt
     8701 taaatttaag taaagcttac taaaggtaag cagatggttc gctatccaag tatagaaatg
     8761 ctatactagt catagatttt aaaaatggag gtctttgata tgtcacaagt aattacagat
     8821 aagacattta atgaagaaac agataaagga cttgtattga ttgatttttg ggcaacttgg
     8881 tgtggtccat gtcgtatgca agcaccgatt ttggatcagt tggaacaaga atatgatgaa
     8941 gaagaattca gaattgctaa aatggatgtg gatgaaaatc cagaaactcc tcaacaattc
     9001 ggtatcatga gcattccaac attaatgttg aaaaaagatg gtcaagtagt agaaaaagct
     9061 gttggtgttc attcaaaaga acaactacgt caaatgatcg atcaatattt ataaaaactt
     9121 acagcaaaaa taagctgagg gtgggactga atccagttcc gtcctcggtt tttttgcggt
     9181 tgagttaagg ttattcaaat taatattttt tgagtataat tacgttgtca ggctggattg
     9241 tttttttgac agacatgcta taataacttt aattgaatat gaaggggagt accagatgaa
     9301 cgaacgaatc aaaaacaaat tagctttact tcctgatcag cccggctgtt acttgatgaa
     9361 agataaaaat ggaacgatca tttatgtcgg caaagccaaa atattaaaaa atcgtgtccg
     9421 ctcatatttt actggtagcc ataatacgaa aacggaacgg cttgttagtg aaatcgaaga
     9481 ctttgaatac atcgttacag aatcgaatat cgaagcattg ctcttagaga tcaatctgat
     9541 aaagaaaaat gatcctaaat acaacattat gttaaaggat gataaaacct atcctttcct
     9601 taagataacg aatgaaaaat atccccgttt ggtgattact cgtaaggtac taaaagacaa
     9661 agcactgtat tttggaccat atcccgatgt cggtgcggcg aatgagacaa agaagatcct
     9721 cgatcgatta tttcctctga gaaaatgcaa acctagtcag acgaaggagc cttgtcttta
     9781 ctatcatttg ggacaatgcc tgtgtcctta ttatttcgac gtagatccga aagtctatac
     9841 gaaaatcgtt gatgaagtga aaaacttttt aaacggagga cacgaaaaaa tcgagtcaga
     9901 gatccatcag aaaatggaaa aagctgctga aaacatggag tttgaaaaag ctgcagaata
     9961 ccgagaccag atccgtgcca ttgagacaat catgactcgc caaaaaatga caaatactga
    10021 tttactggat cgagatgtat ttggttatgc gattgataaa ggatggatgt gtgtccaagt
    10081 gtttttcgta agacaaggaa agctaattga acgagatgtt tcaatgtttc ctttctataa
    10141 cgaagcagaa gaagatttct tgacttacct cggtcagttt tatcaggaaa atgagcattt
    10201 cattcctaaa gaagtcttga ttcctgatac gatcgacaag cccagtgtag aagctttgtt
    10261 agctacgaaa gtgctgcaac caaaacgagg agaaaagaaa aaattagttg aattggcgag
    10321 taagaatgcc tcagttgctt tgaatgaacg gtttgatctg attgccagaa aacaggaacg
    10381 gacgatcgga gcagttgaac gtttaggaaa cgcgatgaat atcccgaccc caatacgtat
    10441 cgagtctttt gataactcta atatcatggg gacgaatcct gtggctgcga tggtcgtatt
    10501 cattgatgga aaaccggcaa gaaaagaata tcggaaatat aaaataaaaa cagtcaacgg
    10561 accggatgat tatgcatcaa tgagagaagt catctatcgc agatattcgc gagtgattcg
    10621 cgaagggttg cctttacctg atttgatctt gatcgatgga ggaaaaggac aagtagatgt
    10681 ggcaaaagat gtcttagaaa atcaattagg aatcgatatt cctattgctg gcatggtaaa
    10741 aaacgataaa cataaaacaa atgagttgct attcggtaca gatttggctg tagtaccgct
    10801 tgagcgaaat tcaccagagt ttttcttact ccagcgaatc caagatgaag tccatcgatt
    10861 cgcaatcact ttccatcggc agctacgcag taaaaacagt tttgcttccc gattagatga
    10921 aattgaaggg ttaggaccaa aacgaaaaaa aatgctgctt aaagagttca aatcgttgaa
    10981 aaatatcaca gcagccacga cagaagaatt acaagaaatc ggactgccga aaaatgtcgc
    11041 acaaaacgta tttgataaat tacatcagga atgaggaaag ggcactttac aaagaaagta
    11101 aagtgtccta tcattttatg tacaacaaaa agagcgttta cgttttgttg gtaaataata
    11161 aatcgcttac gtctggtgtc taaggatata tgtgatttct tgaagaagga gtgaagaaat
    11221 gttagaagtc aaggatcttg ttaaaacttt tgggaactac acagctgtcg atcatgtctc
    11281 tttccaaatc cccgatggaa aaatcatggg gctaattggc caaaacgggg ctgggaagac
    11341 aacgactttt cgtttgatct tggatttttt gacacaagac caaggagaag tgttatggaa
    11401 tggccatcat cttggggaga aagattatga tgtcatcggt tatcttccgg aggaacgggg
    11461 actttatccg aaagtaacga ttcaagacca actgctttat tttgcagaac ttagagggaa
    11521 atcaagaaaa gagattgaac caaaaatcga cttttggatg gaaaaatttc aggtaaaagg
    11581 gaaaaagacg gataaagtaa aatctttgtc taaaggaaat cagcaaaaag tccagctgat
    11641 cgccacgtta atccatgaac ctaaattgat cattttggat gagccattca gcgggttaga
    11701 tccggtaaat gctgaattgc taaaagatgg aatattggaa ttgaaaaaac atggttcatg
    11761 tgtcattttt tctagccaca atatggataa tgtagaaaaa atctgcgatc atttgatcat
    11821 gttgcgaaac ggaaaaatgg ttttgaatgg aaaagtacat gagattcgtg aatcatttgg
    11881 ccgtacgaag ttattcttgg aatctggttt aagccaacag gaagtagaag aaatcgaagg
    11941 cgtgaaaaaa gtgatccttc atgaagacaa tacgttagag attaccttag aagatcctga
    12001 agctgggaaa gaaatcttta ctcgtgcgac tcagttcggc tacattccta tgtttaacca
    12061 gcaaccgcca actttggaag agattttcaa attgaaagca ggtgaaatcg atgcgtaagt
    12121 tttggattat taccaaagat gtctatttaa aaaatgttaa gtcgatttct ttcttgatca
    12181 tgatattagt cccttttatc atgctgggta tcatttatgt agcaggaaac tttgctcaac
    12241 aaaatagtga tgtcaataaa atcggcgtat tggctgataa tgagcaaatc agtcagcaaa
    12301 tgagccaagt caaaacagat gattttgagt tcaaagcagt tgattctgaa gaaaaagcac
    12361 aaaaagagct ttcggaagaa aaaatcgatg cgtatttagt agtctcaact gagaatgata
    12421 agataaatgg gatgctttat agcgaaaatt cattaggaca aagtacacaa ctactgatac
    12481 aacaacaact gactggcttg caatcgatgc ttcgagcgag tcaattaggc atttcaccag
    12541 aagaagtagc tagcttgagc caacaagcaa gtttgactcg acaaaaagtc aattttgatt
    12601 caaaaggaaa aatgacagtc ggagaagata actcgacagt ccaatacgtc gtaagttatg
    12661 tagcaacgat tgtcttgttc attattattt tgacgtatgc gcagatcatt gcacaagaga
    12721 tcgcttctga aaaaggcacg cggatcatgg aagtgatcct gtccagtacg actgcacaaa
    12781 agcattttta cggaaaatta acaggtgttt tacttgttgc attaacgcaa atggcattat
    12841 acggtattat ttttggtata ggatacagtc aattcaaaga tatggaaatg gtcaaaaata
    12901 tattagacgg tatctcattg gataacttga ttggaccatt cttgtggtat tctcttctat
    12961 tcatgatctt tggcattttg attttttctg ttttagcagc tttatgtggc tctttggtca
    13021 acaaagcaga agatacagca aaagcaattt tgccagtgac ttatctatct ctaggcggat
    13081 acatgcttgg attgatacta ggagcttcag atccaaacaa tatcgttatt cggatcactt
    13141 cgtatattcc attcttatct tcatatatta tgccgattcg cttagcaaat gagacagtcg
    13201 gtatgggtgg agcattgatt tccttgttgg tacttgtagc cgtaacattc ttattgatga
    13261 tcttgtctgc aaacatgtac aaatcgaatg tactcgttta tagcgaaggc ggattatgga
    13321 gttcattgaa acaatcgatt tcaattatga ggaatgaacg aaaaaaagca taaaacaatc
    13381 ctaaaataca gaaggaagct ggacatctat tgttcccagc ttctttttgt atagacctat
    13441 tttatttatt ttactatatt ggatatatat tcattgaaaa tagtgtataa caactttata
    13501 atattgagta taccaatttt tggaggcgtt ttaatggacc gttatttaga tttactttca
    13561 gaaaaattcc cctcaacgga ggatgtcatc acggaaatca tcaatctcga agcaattttg
    13621 cagcttccaa aaggaacaga gttatttttg agtgatatac atggcgaatt tcctgctttt
    13681 gatcatattc tgcgtatcgg ttcaggaaat cttaaagaaa agatcaaaga ccttttttct
    13741 gaacaaatga cggaaacgga tatcagccaa ttcactattt ttacggctta tccagaatat
    13801 gcattaacga ctgattggta caaagaacaa gataaatcgc agctgatcca tcatttgatc
    13861 gatcttttac ggtttacgac agtcaaatat acccggtcaa aagttcgaaa aggattgccg
    13921 aaagaatata gctatatcat tgaggaactc ttgtatatcg atgaccgtat caatggaaaa
    13981 aaagactatg taaaaaaaat cattgaacaa cttgttttga tgaaggaaga agaaaaattt
    14041 ttaacgaaac ttgcacagac gatccaaaaa tctgtcatcg atcatttgca tatcgttgga
    14101 gatatttttg accgaggaac tcaagcagcc aaagtgatgg atcgaatcat ggatttttct
    14161 tctgtagata tccaatgggg aaatcatgat attttgtgga ttggtgcgta ttgcggctct
    14221 gaggcatgtt tactgacact tttacggatt gcagcacgct ataattattt atttgaatta
    14281 gagaaagaat atgggttgaa tttacgtcca ttgttttctt ttgctcatca aacttatcag
    14341 aagaatccag tatttgcgcc taaaaacagt aaaaatctat ccgaaagaga gcaagaagaa
    14401 ttagaaaaaa tccatcaggc actttctatc cttcaattca aatcagaaca tcagttattg
    14461 gatcgtcgac ctgaatttaa aatggacgat cgtaaattgc tggaaaaaat cgactatgaa
    14521 gcatcaacga ttgatttaga aggtcagctc tatgagttga aaggaacttg ttttcaaacg
    14581 atccagccag atgatccaaa aaaattcttg gaagaggaac aaaaagtgat tgatagtttg
    14641 atgtattcat tccagcactc tttgagaatg caaaaacata tgacgttttt gatcgaaaaa
    14701 gggggaatgt atctcacgaa caatcagcat gtgctgtttc atggctgtat acctgtagac
    14761 gagaagggac agctcttagc atttgaatta gaccaatctt atcgcggaaa agaactgctg
    14821 ggcttttttg aaaaacagat aactgaaagc gcaaaagatc tgactgcaaa agaagattta
    14881 gcaaccgatt tgatttggta tgcgtggagt gggccatttt cgcctttatt cggcaagagt
    14941 aaaatggcga cttttgaacg ttattttctc acagagcctc atacgcacgt cgagaaaagc
    15001 aatccttatt atcacttgcg agatgaagag tggttcagtg aaaaaatttt agcagaattc
    15061 gacacaaaag aagaagggtc agcaatcatt aatgggcaca cgccagtaaa agtaaaaaaa
    15121 ggggagtcac cgatcaaagc aaatggaaaa gtatttgtca ttgacggagg tttatccaaa
    15181 gcttatcaaa aaacgacagg aattgccggt tattcactat tatgcaattc ttatggtttc
    15241 caaatcgtga cacattatcc gtttttgcct attgaacaac aatttgcaaa aaaatccgac
    15301 caaacaaatg tgaaaaaagt aatcgaacag caactaccac gcaaactcaa tcgtgataca
    15361 acaaaaggta tggaactgca gcagcagatt acccagctca aaaggctgtt ggactatcga
    15421 aaggacgatt gagaagaatt ccagtgaaca ttgttccata gactggagac tgagacaaaa
    15481 gtcgtgtcgc agtctctttt tccggataaa cggtgttctt ctgccaactc ctcggtcaca
    15541 agtcacacta ttcaacaaac atgaaaagct gttttttgaa attgctcctt gtgactcaga
    15601 gttgaacggc aggctcacga cctcttggta taaacggtgt tcaaaagcca gtttctcggt
    15661 attaagccaa atttatgcaa aaatgtgaaa agccattttc acaaaatttt tcttaatact
    15721 cgaaactaaa cagctttttc acaaccccct cagaaagtct attaaaattc attcacaaag
    15781 aaatcgaata agcgctgttc agatggatgt acacggtggg taagttccgg atgccattga
    15841 acaccgagga ttttatgcat atcatctttg ctttgaaccg cttcaacgag tccatcgtta
    15901 gaaaaagcga tggcttttaa taaaggtgaa agatctttga ctgcctgatg atggtaagaa
    15961 ttcacaaaat atggatcggg gagaaggttg cttaacaaac tgtctgaaac aatcttgact
    16021 tcgtgagtcg taaattgcgg ggcagtgggc tgttgttcat gttttactga ccactttgga
    16081 tataatgaaa gatcttgata aagtgtacct tccaaaacga cattcaatag ttggagtccc
    16141 cggcagactg caaaaattgg ttttctttgt ttcaatgctt ccaagatcag tgcctgttca
    16201 aattggtctc gttgaatatt tgtttccgtt agctttggat gaggatcttc catgtaaagt
    16261 tgtggactga catcttgacc acctgcaaga ataagtttgt cgatttgtcc aatcagttga
    16321 ggagctgaat ctggagacat gactggcaga ataagaggca atccttgagc atctaaaact
    16381 gcatccacga atccttgcgg tgtatagctc acttgatttc cttggaaagt atctgttgct
    16441 cgaatcagtt gatttccggc aatgccgatg attggtttca tttgtattcc ccctaaagta
    16501 gacttattgt aacaaggatt taaaaaaaat taaactatgt aagacttgcc cctatactta
    16561 tctgttcttg ctgtgttact atctgtaaag agaaatttcg tgtgaaattc atgacgatag
    16621 ttgaaaatat tgcttaattt gttataataa aaagtaagca gaaataaaaa ggttgggcgt
    16681 aagcttcaag gatctagttc ttcaaggggt gagaaggaca ttttattgaa ggggcctgcc
    16741 tatactaagt tatctttaga ggtacatact ttcaatgaaa aaagaaagca tgtacctctt
    16801 ttttaaatcg aaaggaagtg aagcaagtgt tagaagcttt ggaacaaatc cgaaaagcag
    16861 aagaagaaaa tgaaaagcgt gctcaaacac tgcggcagca gctgaagatc tatgcaacag
    16921 aaaaagagca ggaattggaa acgatccaaa caaactatcg acaacaacta aaacagttgg
    16981 tggaagaaaa agaacaattt gaaatacaag aattagaaaa agaaaaaatg aaattgaaag
    17041 cagaagcaga caaggtgcaa gcaactttga aagatcaata tcaaaagcat cagagtcaag
    17101 cgatcggtgc gatcattgaa agggtgaaag aaacttatgg ccgtcactaa gatggaaaaa
    17161 gtgaccctca tttcagataa aagaaatcag gagaggattt tacaagcagt acaaggaatc
    17221 caaaacgttg aaatccggga tctgtatcaa aatagaacaa acaaccagtg ggtggagaag
    17281 tattttccag ataccacgat tattgataaa gaagcaaaat taagcgcttt aggtaatcgg
    17341 ttgaaagaca tccaagaagc tatccaattc atacaacacc acggcgatag ccgtcaaaag
    17401 aaactccatt tgaaacgtca agaactttcc ttacaagatt tggaagccaa ttattccgaa
    17461 gaaaatttca taaataaatt gaaagaagtc cttgatttaa aagaaaagtg ggaacaacta
    17521 actgaagaac gtgatcgttt agaagaagag gaagaatggc ttcttcattg gcaacagctg
    17581 gatattgctc caagtatgta tgcaagtaag acgaccattt ttgagatggg gactgtgagt
    17641 gcagcaaatt ttgaaagttt caaggaagaa ctgagtaagc ttgatgacgt ttatatggaa
    17701 gaaatagatt atacgccaaa acaagtttat ctttcgtatg ttgctttaaa aaaatcagtt
    17761 gctgttatag aagaaattgc tgggaaatac gggttcaata aagaaacgta tccttatgaa
    17821 caaaatccta aagaaaaact gcaagagacc aagcagcaat tatccattgt tcacgagcag
    17881 caaaagaaga taacgacagc gttaggtcag tgcagtggct atatccaaga atttgaatgg
    17941 gtagaagaag tcacacttgc cgttgcagaa cgagaaaaaa taaaagaacg gtttatccat
    18001 gcgacttatc tgatcgtttt gcaaggttgg gtagatgcag aagaaaaaca gaatttgctg
    18061 catgtgttaa acgaaaccgt atcagaagaa gatatatacg tcagtttcga aacaccaaac
    18121 tcagaagaga ttcagcagga agtccctact aaattgaaaa accatccgct tgtcgaacct
    18181 tttgaattgc tgactgaaat gtacagtctg ccaaaatatg aagaagtaga tccaacacct
    18241 tggatgacac cattttatct tgtcttcttc gggatgatgg tcgcagatgt tggttatggt
    18301 ttgctgatgc tcattgggac aatactagct caaaaactac ttgttctacc acgcgggatg
    18361 aaacgtttcg taaaattctt tgagattctc tcgataccat cgatcatctg gggattgatc
    18421 tacagttcat ttttcggaca gtcattacca aaagaactgt ttggcatccg cttgcctttc
    18481 ccaatcctat ctacgacgga tgacgtcaat acgattttga ttttatccgt gattttcggt
    18541 ctgatacaga ttttggttgg attatttgtg gcagcaaagg aaaatatcag gagaaaagat
    18601 tacttgagtg ctgtcagtga tggatttgcc tggcaaggga tcctaattgg gatcgttatt
    18661 gcgttggttg gtgccatgtt gataaaaaat acagcatttg tttaccttgg cgctgggcta
    18721 tcgatcattg ctgccttatg tatcttgatc gttccgatta tccaaacgcc gtctaaagtc
    18781 aaaggtgctg ccaaaggtgc gtataatctt tacggactga ccggctatat cggtgattta
    18841 gtcagttata cacgtttgat ggcattgggt atttcaggcg gaagtattgg agcggcattc
    18901 aatatgctag ttgctttcat gccgccagct gctcgattca gtgtagggat ccttttgatc
    18961 atcgctttac acgcactgaa tatgtttttg acactgctaa gtgcctatgt ccatggcgca
    19021 cgattgcagt atgtcgaatt ttttgggaag ttttatacag gaggcggacg tgcctttgat
    19081 ccgctgaaaa cggcggaaaa atacgtcaac atcaatcaca agaaaaaaaa caataaataa
    19141 ttggaggatt tttatataat gatggattac ttaattagtc aaaatggtgg aatggtattt
    19201 gcggtattag cgatggcaac agcgacgatt ttttcaggga tcggttcagc taaaggtgtt
    19261 ggaatgacag gtgaggcagc agcagcattg acaacaagtc aacccgaaaa attcgggcag
    19321 gctctgattc tgcaattgct tccaggcacg caaggtttgt atggattcgt tattgccttt
    19381 ttgattttta tcaacttagg aaatgacatg tcagttgtac aaggactgaa ctttctaggt
    19441 gcttctctgc cgattgcttt tacaggcttg ttttcaggta ttgcccaagg aaaagtcgca
    19501 gcggcaggta ttcaaatttt agcgaaaaaa cctgaacatg ctacaaaagg aatcattttt
    19561 gctgcgatgg ttgaaacata cgcgatttta ggtttcgtta tttccttcct attagtgttg
    19621 aatgcctaag cataaaggag gaaaagcaga tgaacgccat tgaaaaaatc atctctcaga
    19681 tgaacgaagc agcagagcag gaaagagcgg cgttagaaca agaagagcga atgaagatcg
    19741 atcaaaactt tgaacaaaaa cgtacgcaag ttgaaacaga acatcaaaaa caaaaagaaa
    19801 aacaaatcga attactcgaa aaaaaatacc gtcagctaag gaatcgccag caagtagaag
    19861 tacgacaaga aaatttgaat gcgaagcagg aatttttaag acgattgttt gcagatgcgg
    19921 taactgaaat ggaaaattgg gatgaatctg aacaaatcca gtttatcaaa aatgcattgt
    19981 attcattacc tttgacagga aaagtagcat tcattgctgg agaaaaatca gcagcctatc
    20041 tttctcagac gttgttggat gaatggaaca atgaacttcc ctttatgatg gttttaagtg
    20101 atgaaactgt tgctgatcaa gcgggttttc tgataaacga tcaaggagtt cagtataatt
    20161 ttcttttcag cagccttgta caagatatcc aaggaacgat gagttttgag attgccaatc
    20221 aattattcga ataaggaggg atcagtgtat ggaataccac gaactaaatc ccttgattcg
    20281 cggaagagag cttgaacttt tgtccaatga gacatttgaa cggatgattc aaacaaattc
    20341 tgtcgaagca cttggtgaaa tattgaaatc cacgatttac agtccatata tttatgacgg
    20401 atatgaatat gacttcgaac agaatctttt aaaggagcag agccgtctat ttcgctggtt
    20461 aaaggaatca gcaccggagc ctgaaatcgt ttggatctat acgatgcgtt atactttcca
    20521 taatctgaag gttttgacaa aagctgagat gacaaatcaa aatctggacc atttgtatat
    20581 cgacgatgga ttttattcat tagaaacctt gaaggatgcc attcatacgc aagtttcaaa
    20641 tgaacttcct gaaagcatta tggacagtat acgagaagta cgtgattatt ttgaagagtc
    20701 taccattctt cagggaattg acgtgattta tgatcgacag tttttgacag agcagcgacg
    20761 gcttgccgat aagctaggat atcaagaatt gctgacagaa gtcattgctt ttattgactt
    20821 gaccaatatc acaacgatgg ctcgaggaat attgcagaaa agaacatatg ggttcatgac
    20881 gacggtactt tccagctcgg gaagtatcga aaaagaagta tttttgaact ttgtagataa
    20941 agatatggaa gattacacga attttctatt agagacagat tatgctgatt ttctgcgccc
    21001 tgtcatccgt gagggaaata ttgatctcgt aaagcttgaa cagttgaaag atgattatct
    21061 aagttcattg tatcaagaag cacaaaccca ggctttcgga ccactgccac tactagcctt
    21121 tttgaacgca aaagaggtag aaagcaaaaa ccttcgttta ctggttatcg gcaaaagaag
    21181 ccatttcgaa tcagaaacaa tcagaaagcg ggtgagacaa gtctatgacg cataagatcg
    21241 gtgtagttgg cgacaaagat tctgttttgc cattcaaatt gtttggcttt gatgttcgtt
    21301 atggtacaac caagcaaacc gttcgtcagg caattgaaga aatggcaaag aatgagtatg
    21361 gcgtgattta tgtcacagag caatgtgcag cattgagccc agaaacgatc gaacgttaca
    21421 aggaacaaat gatacctgct atcgtattga ttcccaatca tcaaggatca ttagggatag
    21481 ggctggaaga aattcaaaaa aacgtagaaa aagcagtagg tcaaaatatc ttatagtatg
    21541 aaaaggagat agaaattttg caaattggaa aaatcataaa agtctccgga cctcttgtaa
    21601 tggctgagaa catgtctgat gccagtatcc aagacatgtg tctagtggga gatctaggag
    21661 ttatcggaga aattatcgag atgcgtggcg atgtggcgtc tattcaagta tatgaagaga
    21721 cttctggaat tggtccaggc gaaccggttc gctctactgg tgaagcttta tctgttgaat
    21781 taggaccagg gatcatttca caaatgtttg acggaatcca acggccatta gataccttta
    21841 tggaaatcac acaaagtaat ttcttagggc gcggagttca attgcccgca ttggaccatg
    21901 agaaaaaatg gtggttcgaa ccaacagtag aagccggaga aacggtgagt gctggagatg
    21961 ttatcgggat cgtagaagaa acaaaagtta taaaacataa aatcatggtg ccaaatggga
    22021 taaaaggaac gatcaaaaca atcgaaaaag gttcattcac tattgatgaa acagtatgtg
    22081 tcattgaaac cgaaaatggt gacaaaaatt tgacgatgct tcaaaaatgg ccagtaagac
    22141 gtagtcggcc aatcaaagaa aaattaaacc cggatgcacc catgatcact ggacagcgag
    22201 tgattgatac attcttccca gtgacaaaag gaggagcagc agctgtacct ggtccttttg
    22261 gtgcagggaa aacagtcgtt cagcatcaaa ttgcaaaatg ggccgatgtg gacatggttg
    22321 tctatgtggg atgtggcgag cgtggaaatg agatgacgga tgttttaaat gaattccctg
    22381 aattgattga ccctaataca ggagaatcgt tgatggaacg tacggtattg attgctaata
    22441 catcaaatat gccagtagca gctcgagaag cttctatcta tacgggaatc acaattgcgg
    22501 aatatttccg tgacatgggt tatgacgttg ctatcatggc agactccact tcacgatggg
    22561 cagaagcact tcgtgagatg agcggacgtt tggaagaaat gcctggtgat gaaggttatc
    22621 cagcttatct tggttcacgg cttgcggaat actatgaacg atctggaaga gtcattgcat
    22681 taggatcaga aggtcgcgaa ggaagtataa ccgcaatcag tgctgtatcc ccgtctggag
    22741 gggatatttc ggaaccagtc acacaaaata cattgcgggt cgtaaaagta ttctggggtc
    22801 ttgattccag tttagcccaa aaaagacatt ttccttcgat cgattggata caaagctatt
    22861 ctctttattc aacagaagta gggaagtata tggatcatat ccttcaagct gactgggcat
    22921 ccatggtcac cgagggcatg cgtattttgc aggaagaaca gcagctgaat gaaatcgtgc
    22981 gtttggtagg gattgattcc ctttcagata atgaccgtct gacattagaa gtggcaaaat
    23041 ccattcgtga agattatttg cagcaaaatg cttttgatga tgtcgataca ttcacttcaa
    23101 gagagaaaca attcaaaatg ttgaagatga tcttgacctt tggtgaagaa ggacgccgtg
    23161 cgttgtcgtt aggtgcttat ttaagtgaga tcatggacgg taccgtatcg attcgtgaaa
    23221 ggatcggacg aagcaaatat atcccggaaa cagaattaga aaaactagat caaattattg
    23281 gtgaaatcaa gcaaacgatg caaacgatcg tttcagaagg aggcatgagc aatgattaaa
    23341 gaatatcgta cgatcggtga agtcgtcggt ccattgatgg cggttgaaaa agttgctggt
    23401 gtcaaatatg aagaattaat cgaagtccgt atgcaaaatg gcgagattcg tcgtggacaa
    23461 gtattggaag tccaagaaga taaagcaatg gtccaaatat tcgaaggaac aagtggtatc
    23521 aatttacgtg actcttctgt acgattttta ggccatcctt tagaactagg tgtatcggaa
    23581 gacatgatcg gtcgagtatt cgatggtttg ggacgaccga aagataacgg accagagatc
    23641 ctgcctgaaa agcatttgga tattaacgga gaagtaatca atccagtagc tcgggattat
    23701 ccagatgagt ttatccaaac aggtatctct gcaatcgatc atttgaatac attagttcgt
    23761 gggcaaaaat taccagtatt ttctggctct ggtcttcctc ataaagaatt agctgctcag
    23821 atcgcgcgac aagcaacggt actcgattca tcagatgatt tcgccgtagt ctttgctgct
    23881 attggaatca cttttgaaga agctgaattt ttcatggaag attttcgtca aacgggcgca
    23941 atcgaccgtt ctgtcatgtt tatgaattta gcaaacgacc ctgcaatcga acgtatcgct
    24001 actcctcgta tggctttgac tgctgcagaa tatcttgctt atgaaaaggg aatgcatgtt
    24061 ttggttatca tgacagacat gaccaactat gcagaggcat tgcgagagat ttctgcagca
    24121 cggcgagaag ttccaggaag aagaggatat cctgggtatc tttacacgaa cttagctact
    24181 ttattcgaac gagcaggaag aatccgcgga ctaaaaggat cggttactca aattccgatt
    24241 ctaacaatgc cagaagacga taaaactcat ccaatccctg acttgactgg ttatattaca
    24301 gaaggacaga tcatcttgac tagagagctt tacaagagtg ggattcagcc accaattgat
    24361 gtactcccgt ctctttcgcg gttaaaagat aagggaactg gacccggaaa gacaagagaa
    24421 gaccatgcag ctacgatgaa tcagcttttt gcagcctatg cacaaggaaa acaggcaaaa
    24481 gaattagccg tagttttagg tgaatctgct ttatctgatg tagacaagat ctatgcgaag
    24541 tttgctgagc ggtttgaaaa agaatatgtc aatcaaggat tctacacgaa ccgttcgatt
    24601 actgaaacac ttgatctagg gtgggaactg ctatcgatgt tgccaagaac cgaattaaaa
    24661 cgaatcaaag acgacatgct ggacaaatat ctgccagaag ggaagtgagt tctgatggca
    24721 cgattgaatg tgaatccgac ccgcatggaa ttgactcgat tgaaaaaaca gttgacaact
    24781 gccacaagag ggcataaatt attaaaagat aagcaagatg aactgatgcg tcaattcatc
    24841 ctgttgattc gaaagaacaa ccagctgcgt caagaaatgg aagagtctat gacagaagca
    24901 atgtctgatt ttgtattggc aaatgcttcg atcacggaac ctttcatcga agaattattt
    24961 gttttgccgg cggaaaacgt tgatttgtct atcgtagaca aaaatatcat gagtgtaaaa
    25021 gtacctgtga tgaattttga atatgatgaa cagctgacag acacaccttt ggaatacggg
    25081 tatttgaatt ccagtgccga actggatcgg tcaatcgatc ggtttactac cctgcttcca
    25141 aaacttttgg aactgacaga aatcgaaaaa acttgtcaac tgatggcgag tgaaatcgaa
    25201 aagacacgtc ggcgagtcaa tgcattagaa tatatgacga tccctcaatt agaagaaacg
    25261 atctattata ttcgtatgaa gctggaagaa aacgagcgcg cagaagtaac aaggttgatc
    25321 aaagtaaaaa atatgggtac cactgactaa gtggtatctt tttttaaaag aggaaaacga
    25381 tgattaaaca aagcaaacaa ataaagaaac gtttgccggc tgttcagctt ctcgcattag
    25441 gattttttct cctgatttta gttggcggcg gcctacttac cctaccattt tttagtaata
    25501 gtgggcatgg gacaaatttt atcgatgcgc ttttcactgc aacttctgct gtctgtgtaa
    25561 cgggattgac aacattgaat acagcagagc attggaacag tgctggtcaa tttttgatca
    25621 tgcttttgat tgagatcggc ggtcttggtt ttatgatggt tccgattcta tgctttgcat
    25681 tgataaagaa gaaagtcagt ctcagcacac gtattatatt aaaagaagcg ctgaatctag
    25741 aagaagtatc aggtgtgatg aagctcatgc tttacatcct aaaattggcc tttgtgatcc
    25801 aattgattgg tacggttgct ttatcttttg tatttgtgcc tgaatttggc tggttgaaag
    25861 gtatctggta cagtttgttc catgcaatct ctagtttttg taatgcaggg tttgatttgt
    25921 taggagacag tttagccaat caccagcaaa atgtttattt gatcatggtg gtatctgctt
    25981 tgatcatttc tggtgggtta ggcttcatcg tatggcgtga tttactggaa tatcatcaga
    26041 aaaagaagat gacgattcat tcaaaaatcg cattaaccgt tacaggtacc cttttattag
    26101 gcggattcgt tgtgttcttt ttcacagagc gcaatggggc aacgctagtg gaagggaata
    26161 tgtttcaacg attggcaaac acctttttta tgagtgtgac acctagaacg gctggatatt
    26221 attcagttga ttacctccat atgagccatg caggtctgat tttaacgatg tttttgatgt
    26281 acatcggcgg aacatctggg tcgacggccg gcggattgaa aacaactacg ttaggtgtgt
    26341 tgctgatcca gatgcgttcg atgttgaaag gacgtacgag agcggaagca tttggccgta
    26401 ccatccgaca aggcgcagtg ttgcgggcac ttactttatt ttttgttacg ttgacgttgt
    26461 gtgtagtcgc catcatgatt ttatcggtga ctgaaacgat acctaaaact tctggcatcg
    26521 aatatattgc ttttgaggtc ttctctgcgt ttggtacagt aggtcttacg atgggattga
    26581 cgccagactt gactgcaata gggaaattga tcattatagc gcttatgtac attggacgag
    26641 ttggtgtatt gactgtggtc ttctctctga tgacaaaagc acaaagaaca caatcaaaat
    26701 acaaatatcc agaagaaagt gtcatgattg gataatttca tcttctgaca gaaacctagt
    26761 gatttagtaa aataagaaaa taaaataatt tttcttgctt cttggatact ttaagtgcaa
    26821 aatgttcgtt tattttttga ggcactaccc gttgttgaac ctcgggtagt gcctcttttt
    26881 tattgaaagg aatcaataag atttgattcc tttatttatc aataggttat aattcatatt
    26941 tttttatttt ttcttttacg atacttagtc cagaagctaa aatttcaagg ttattagagg
    27001 atagggaaat tcgaacgaat gcatctggtt gcgcacgtgt agtaaagcgt ctggaatgat
    27061 aaagtcggat accgttagca agaaagtcat tctcaattat cttagggtca atctcaggat
    27121 caactggaag aattcgatag taagggacac gattcgttgg tttttctact ttgaaaagag
    27181 aatcaaaaag ctgattggct ctttttgtaa gacttaattt agtttctaag atcctatttg
    27241 cttcatttga atggaggatt tgagtgatga cttccacatc taatccagaa gttttcacat
    27301 ttatattaaa aattgcttgt tctatcttgc tttggacatg tactggaact acaagataag
    27361 caactcgcaa tccagaacaa ataaattttg tcattccagc taagtagatt gtttggttag
    27421 gtaataaatt ttggaaagga ggaatgatcg tatgttgata gtaagttgtt aaaaatgaat
    27481 ggatatcatc ttcaataacc catagacctt ctttttcaat cacttcggct aattgctctc
    27541 gtcttttgtg agagatttga aaccctatag gattattaca agaaggcata agaaagacac
    27601 catgaatctt cttttttcta cattcctgaa tcaatatatc aggtcgcatt ccttgctcgt
    27661 caaaatcaat tggaacgatc tctaaatgat ataactgagc caattcaatg aaattagcgt
    27721 atgtatatcg gtctgttgct attctatcac ctggagagaa aagtgcagaa agtgtgatag
    27781 ccaatccatt ttgaacaccg gaaacaatag atagagattc taaggacgga atgactcctt
    27841 gagtttttaa ccaatttgct gcagtagtca attgaaaatt tgtgcctttg ggatcttggt
    27901 aattaagcaa accaacaaga tttgggttat tactagttga ttgaataaac gggacaacga
    27961 atttattaca ttcttcaaaa gaactaacca gaccaaaatc aatgatatgt tcggttactt
    28021 cattggtaga gatggtgatg gactcaaaga cattgggaga aataaatgtg ccacttccaa
    28081 tattcgtata cagcaaacct ttctcaattc catatttata agccttgcca acggtagtaa
    28141 aatttaaatc taaataatca gctagctctc tttgggaggg taactgagtg tttttctgta
    28201 atttattctt taaaatatct tgttctaatt gttgaatcaa cgatcgataa taaggacgct
    28261 tcaatttttg tttgtctggt cgccaagtta acgggtaatt gtcataagaa ttaataggca
    28321 ttttctccac tccttaaaat tgtataccat acaattttac cattgattgt attgatttta
    28381 gaagttaatc ttttgtgagg agggaattgt ctatgaaaat tattaatttt gaggaagtag
    28441 tagcttcttt tagttttgaa gaagcgattc aagtaatgaa aaaatgtttt tttgattatg
    28501 aaagtggtaa aatcagccaa aatcctcgat tggtggaaat tttacctgac ggaaaaggca
    28561 aaaatatgtt tgcgatgatg cctgcttatt tgggggagaa cagatatttt ggcacaaaag
    28621 tcattaccgc ttttccggat aatcatcagt atcatttacc ttctcattta ggagagattt
    28681 tcttgtttga tgctcaaaac ggactaccca aagcattgat aaacgcaaat gcagtcacct
    28741 ggattcgaac agctgctgta tctgcgctgg caacagatta cttagcaaat ccgcatgcag
    28801 aaacacttgc tttaattgga gctggtcaac aagcattgtc gcatttgact gcgatttcta
    28861 ccattcgtcc catcactaca gtgtttgttt acgatatttt agaagaaaga cgaaatactt
    28921 ttatcgctaa agctaaaaaa cagtatccta aaataacgtt tataaataca atatcagtag
    28981 aagatgcagt acgtccagcg gaaatcattt gtacgttgac ctctagtaaa gaggcatttc
    29041 ttcaaaaaga gtgggtaagg gaagacgcac atatcaatgc tgtgggcaca tttactcctg
    29101 atacaagaga gataagtaca tcgttgatgg aaacttctca aatctatgta gatgattact
    29161 cagctgcctt aacagaaagc ggggacctgc ttatagccat ggcagaagga gatttagagg
    29221 aatcttgtat tgttggtaca ttaggcgaat tagtttctga gaaaaaaaca ttttataaag
    29281 gagaatcgag gccgacgatt ttcgacgcag ttggtctagc tattgaagat ctttgttgtg
    29341 cagaatatat ttataacaaa ttagagaaag gggctttaaa atgaacttag attattacgt
    29401 agttgatgca tttgcagatg aggtgttcaa aggaaatcca gcagcggttt atgtgctaga
    29461 agaatggctg ccagaaggta cgatgcaaaa aattgccatt gaaaacaatt tatctgaaac
    29521 agcatttaca gtgaagaaaa accaagaatt tgagcttaga tggtttacgc cagatcgaga
    29581 aatcgatctt tgtggtcacg cgacattagc aacagcattt gttttattta actattacaa
    29641 aatacctgat gaaacgatta aattttctac tcaaagcggt aatctatttg tgacaagaat
    29701 taaagattat tattacatgg attttcctag tattatgccg aaaaaagtgc cgatattgtc
    29761 tgaatatgaa gaagcgattg gggctaagat taaagaagcc tacttagcac gtgatttatt
    29821 tttcgtatta gaagatgaaa aaacggtggc taaattgcag ccagatttta cagctatcaa
    29881 aaattttgaa ttaggaatag gagtcatcgt gacagcagaa agtgtgcaaa aagactttgt
    29941 ttctagaacc ttctttccaa aattaacaat caatgaagat ccagtatgtg gatcagcaca
    30001 ttctaatctt attccttatt gggcagaaag aatgaataaa acaaaattgt cagcttatca
    30061 aatgtcatca aggggcgggg atctagaatg tgaattaaaa gaagatcgtg tgataatagg
    30121 aggaaaagca gttttgtttt ctaaaggtac ctcgtttatt tgatttcttt caaatgaatt
    30181 aaaaataaat tggtggagag tggcaacctt atagctacaa tggttgttaa aaaaagacgc
    30241 aaactttttc aatttaatga aaagtttgcg tctcatttta attattggtg tttgtttttt
    30301 attcaatcaa gagtaaaatg ccccatacta actatcctcg gatgacttcg attttataac
    30361 catcagggtc aatgacaaag tagtaagaag gcgcagtgcc aggtaatcct tttaagtcag
    30421 taatctcaag accggcagct ttatgttgct cgtgtaattt ttctagatca tcagctgcta
    30481 tagcgatatg accatagccg tctcctagat catacgcacc atgatcatag ttgtaagtca
    30541 actctaattc atagtcatcc ccaggaagtg tcaaataaac aagtgtaaat ttgttttctg
    30601 gaaaatcacg gcggcggctt tcttcaaaac caaatgcctt ttgataaaat tcgattgatg
    30661 cttcaagatc tttcactcga acacatgtgt gagccatttt catagattca tctctccttt
    30721 tccttttact caatcataac aaaaagaagt aaggaaatag ttgatttgtg cttgttcatg
    30781 agaaatttct catgtaaaat ggatagaaaa taaaactgtt aaggtggaaa ctattcatgg
    30841 ataaaccaat ttttggtgaa aaaaagcaat ttgctgatta tcaaacccgt tatgcagcat
    30901 atattgtcat agaaagagat cagcagattg cagtaatcga ggctccaaat ggtgcttttt
    30961 ttcttcctgg cggggaaatt gaaggagaag agacgaaaga agaagcgatt gtccgtgagc
    31021 tgatagaaga aatgggaatt gtggcagaaa tttcttctta tctgggagaa gctgatgagt
    31081 atttttactc gaattatcgt gcaacttatt attataatcc aggatatttc tttgttgctg
    31141 attcttggaa gcgtatagga gaaccaactg aaaagaccaa taaaatttgg tgggtgagcc
    31201 ctcaagaagc gcttgtgaaa ttgaaacgtg gtagccaccg atgggcagtc gagagatgga
    31261 tcgaaaaaaa taaaaactga aagaaagcga gtagatcagc tttctctcag tttttttatt
    31321 tattacagta catatttttt gattgcttca gctacaccgt gctcgtcgtt tgatgaagtg
    31381 atgacatttg ctgcttcttt gacaagagaa acggcatttc ccattgctac tcctagacca
    31441 gcatattcaa tcatggataa gtcgttctcg ttatctccga tagccatgat ttcatcttga
    31501 tcaataccaa ggtgctgtgc gagattcgca actgccgcac ctttacttgc ttctttattt
    31561 agtacttcga agtaataggg cgcacttttg accgttgtgt atttatcacg gaaagtttgc
    31621 ggtaaacgcg caattgctgc atctaaaatt tctggttcgt cgatcatcat cattttgacg
    31681 atgttcatgt ctggtgtcat ttcttcaggt gttcgatatt ttagcggcat cttgactaaa
    31741 cttgcttcgt ggatcgtata agcgctgata tctcgattag gcgtgtagat cgctttgtca
    31801 tcgatcgaat ggagatgact gccgacacgg cgtgccatca cttcgatctc taggaaatct
    31861 tcatgtgtca gtccgtgacg ggcgatgatt ttacctgatt tcgtttgttg tacgagtgcc
    31921 ccgttataag taataacgta atcattatct tgaaaaaggt tcaactcgtt taactgttcc
    31981 tggacacctg gtaagggacg gccagtgcat aaaacgatcg aaacaccttt tgcaacagca
    32041 gcggcaatcg cttcttttac ttcttttgtt acttctcttt tctcatttaa taaagtacca
    32101 tcgatgtcga tagcgactag tttgatagac ataatttcct ccaatatatt ttaatttatt
    32161 tcaatcaatg cgccattacg gatatggctg gcaaattctt gataagtttc gtcaaataaa
    32221 tcataatgat cacgcaagga cggatcaacc atttcttttg gaaagaaaaa tcgctcatct
    32281 ccttgttctt gtcccgctaa tgcagcaaca agctgactaa cctgtgataa ttctatcaaa
    32341 gttccgtcat ttcgcaaaat ctcgatttgt gtgcgatgtc tgccttgttc tgggcgataa
    32401 aaatcataag gtagatcgta gctagaattc acagcagtgt aataaacagg attatatccg
    32461 accttttcta ctaacaaagt gagttcttgg actaattttg aatcccggtt gccagaaaaa
    32521 gtagcagatt tcagtggttt acgattcaaa aaacgtttag ctaaatcatt taaaatagga
    32581 tcagcagatt cagaccattg agtaaagtaa gtgcccaaga ccccatcatc aagtttgagg
    32641 tattcttcta aagtaaagct tccgtcaaga aatggcagaa gtaattgaga atggagttca
    32701 aaactgctgg catcttcttg atacaactcg tgtgcgcgat gaagcagatg ctccaaaatt
    32761 acttccatac cacgggaaac aggatggaag tacacttgca catacatttg atatcggcta
    32821 acgatataat cttccactgc atgcatgcca ctcatggaaa aagcgatccc gccttcataa
    32881 ggacgaatca cacgtaatat tcgggtaaga tcaaatgttc catattctgt tccagtgaaa
    32941 taagcatccc gaagcaaata gtccattcga tctgcatcga tctgactaga aatcatttgg
    33001 acaacttgtg ggttggggta agttttttgg atcacactag ctaccttttc aggaaaacct
    33061 tcttctactc ggttaagaat ctgatacact tctgtttctg gagaagtgat gatctctaca
    33121 gtgatggctt catgattcgt atggaagata tgttcaaatg tatgagagta aggaccatga
    33181 ccgacatcat gcaacagtgc cgcacataaa gtcaccagcc gttcctgatc atcccagcct
    33241 ccgttgccta ttttttcttt tgaaaaattt cgagaaaaga tatcgcagat tcgtcttgaa
    33301 atctcataaa cgcctaatga atgagtaaaa cggctatgtt ctgctccgtg aaaagtgaaa
    33361 gaagaagtgc ctaattgttt aatgcgtcgt agacgttgga cttctttcga attgatcaaa
    33421 tctaagatta cttgatgctg gacatggata tagttatgga ctggatcacg aaaaactttt
    33481 tccataggca gcatttgata tttataaggg gttgtcataa tgtagctcct ttatgttatt
    33541 acgttgttcc attctctgga tttggttgtt ccattgctcc agctggattt ctttttttag
    33601 ccagtcggta gaatcctgta aatcacttgc agaatacagc ttttcaaaag cttttgcaaa
    33661 tgcttctttg acttctttta caaaaagggg ttggtcaagc agttcttcaa gtgttgccat
    33721 tgtagcagga tccactgcag gatagccatt tgtaccaaag tcttctttta aagcagattg
    33781 ataaaatcgc ttcatgactt gcccgcgttt ttcctgatta ccgttgacac ttaagtacat
    33841 cataacagaa atcccatttt tgatccgacg ctgagcgata ccggcaaatt ttttgccatg
    33901 gatgcttaaa tcataagttc caggacaata agaatgggtg atttcgaatg cttgtatcgg
    33961 tgcctttgga aaagcgtatt tagtcaatag gagcatttgc tcgtaagcgt catctatggt
    34021 tatttttttt gtgtcacttt gggggaaaat caaagaaata ttcaaaattc cttcatctga
    34081 tacgatccct aatccacctg aatttctgat cactggagcg taacctgcat ctttcagtgt
    34141 ttggatcccg tcacttagaa aaggagttcg aacatccttc atacctaaga tgactgtgca
    34201 gtcatattgc cagaaatgta aaaagatttg ctggtgttct ttagaatatt ccgttaatat
    34261 atctgttaat gcaaaagggg aaaagtcgtt tttttgataa atgtgctgat ctagtcgaat
    34321 cgcagggttc attcaaccgg ctcctttgta taaattcata ttttctacaa tattatactc
    34381 taaaatcaaa gagttgtttt ggaaaaaagg ttttctgtaa aaatggacaa gttggttgac
    34441 aaaacaaaag aaactaggaa caatgtagct atgagaagta aaggagaatg aataatggaa
    34501 ttatcacaag gaacaccgat ttcaatcaaa ttgcgtacaa aagtaaaaca gcaaggggaa
    34561 gtgcaagatt tttattttga tttgaaaggg caaatggtga caattggcga tacgctgtac
    34621 atacgttata aagagattca ggaggagacg ggcgatgaga ttcctgtaac gatcaaatta
    34681 gttccagatg gtcatgtaca gctgatccgt gcaggagaaa tgcggatgcg tttgaaattt
    34741 ggctataaag aacggttaga aacatcctat cgaacaccat acggtatgat ccagattgct
    34801 acttttacga aagaactgca tgttagtttg aaagaccgtc ccacaggagg gaaggttcga
    34861 atcgattatg atctgttcat gggaccggaa aaaatcggcg aatattattt gaccttggat
    34921 tttacagcgt aaatataaaa gaaaagtttg attttttgtg tctgattttg tatgataagg
    34981 agtagactgt gaaaggacgt gtcctgattg gaaattagtg tatttgaagg tgcaaacaaa
    35041 agcgaattat caatgatcga agtagcacac gcgatcttag aacaacgtgg cgatgtcatg
    35101 gatttttctg atttagctaa ccagatccaa aactatcttg ggaaatcaga cagtgaaatt
    35161 cgtgattcac tcgcacaatt ttatactgac ttgaatattg acggcagctt tatctcatta
    35221 ggggataatc gttggggctt gcgttcatgg tatgctatcg attcgatcga tgaagaagta
    35281 aaccatggaa tggacgaaga ggatgaagat actccacgtc gccgtaaacg caagaaagtc
    35341 aacgccttta tcaatgatga tgaagacgcg atcgattaca atgacgatga cccagaagat
    35401 acagatctga cagaagaaga tgacgatgat ctgtttgatg acgatgatga tgaagatgaa
    35461 gaaatcgctg cttataattc tgacttgcaa gaaatcggag cagatgaccc gacagatgat
    35521 gaagaagact tgccaggaaa tatcgaagaa gatttaagta tcatagacga agacgatgat
    35581 gatgaagatt atgaagagga agaattttct gactctgaaa aagaataaac attattttct
    35641 tacgagaggt tgtgacagag acgatcagcc tatcagaata aggaggtgtg acacgatttt
    35701 tgtcacacct tcttttttgt atataaaaat cccaagtaaa tacataaaaa ataaaaaaat
    35761 tgaaactttt agcgcacctt gtacgtcata ttaagtgagg cagaaaggag tggagaatga
    35821 tttttactgg atataagaaa aaacggcaga tcgaaaaata ccgtcacctg ctgaatggac
    35881 tcatcgaaac tgattatcaa aaaatgttcc gtatcacgat gaattacgta catgataaag
    35941 aagaggcctt agatgtgatg caagatagtt ttcataaagc cctgaactat tttgaaaaag
    36001 aaaaagagat cgagcatttt agtgcatggt tttatcggat attgatccgc acggcattag
    36061 atagttggcg cagacaaaaa aggacgcctg tggacttatt tgaaattcaa gatatccccc
    36121 aacagttacc tttagaaact tccgttgcag agctccatat gattttagat aaaatagaca
    36181 gtccggaaaa agagattctg atcctctact tttttgaagg atttcgtttg aaagaaattg
    36241 cgactatctt ggatatgaat gaaaacacag ttaaaacgaa aatgtaccgc tcattgaatg
    36301 ctttacgtca aatcctagaa tgaaggagag aagagtgcca tgtattccca aaaagaaaat
    36361 ttaaaaaaac taaagaaaac ttataaagaa caagcaattc ccaaagggct taaagaggag
    36421 atccgccagc gttttattat cgaagagcaa tcatttataa aagcaaagcg gagaaagaga
    36481 cgtctccaag ggttcggagt atctttggct atcgtaatga ttacaacaag tagccttctt
    36541 tttaatagtc aagttcgaag ctttgcagaa gatttaccca tcttaggatc agtcattgaa
    36601 ttgatcttag gcgaacgctt tactgatcga tctgaaaaaa tcgatattca ggtaccgaag
    36661 atcaatacac aaaatgagaa agaaaataaa acaattcatg gattaaatca aaaatacttt
    36721 cgcgaaggac aagcagattt tgaaaaagct gaaaaagaat atggaaattt tgaaacggat
    36781 cattaccaag ttttgggaga ttatcagaaa atcgtagacg ataaccggtt tctcgtgatt
    36841 gaaaggcaga tcacccaaac agcagcagat agccatgttg aaaaaagata cgacacaatc
    36901 gacaagaaaa acagtgtcca gctctcactt ccacttttat tcaaagatga cacctatcta
    36961 tctgttttga caaaagaagt caaacggcag atggccgaac aagtcaagga agatccatct
    37021 aagtactatt ggactgagca agatattcaa gaagggacga tagaaaaacc aacacttgtt
    37081 acgcctacac gaagttttta tttgaacaaa gagcatcaat tagttttgac tttttctcaa
    37141 tacgaaattg ctcctggtta tatgggtaca ccagaatttg tcattcctaa gtccgtgaca
    37201 aaaacgattt tggcatcgga agattatttg gatcattaga cgagaagtag ttgcgactag
    37261 cagtttcaat tttcaagtaa gtacaagtaa ataataagaa gagaaaaaga gaaagaagag
    37321 atatagtgaa aagaaattat ttagttatca gtattattgc tttatccgtg cttttgtttt
    37381 tcgaaattac ttcggtggcc tccttgatca ccgaagtaaa aggacaaaca cactcttcgg
    37441 agcattcgtc acaatctttc aaacaatcag aacaatcaac cattaaaagc caatcaactg
    37501 aaacagctaa cgtcaaagaa gccattcaag aatcagcgga aaaggtacaa agtcagtcat
    37561 cacaatcaac acaagacagt acaaaaacga gccgagatcc ggctgtcaaa agcgtcgcaa
    37621 tcagctttga tgatggacca ggagcgacca caacaccgca gcttctgcga atcttaaaag
    37681 aaaaaaacgt gcatgccact tttttcgtct taggagaaaa tacggcgcag catcctgaaa
    37741 tcgtgaagca gacagctgaa gcagggcacg agattggcaa tcacacatac gatcatcaga
    37801 atctggccac tctttctgcc cagtcgatga cggaggaagt gacgaaagca gacactgaga
    37861 tcaaaaaagt cactggcaaa acccccactt ttgttcgtcc gccctatggt tctgtcacga
    37921 atgtaggagc aacgatcatc cagcgaccga tcatcgaatg gtctgttgat tcagaagatt
    37981 ggaagacaag aaatcctgat ttgattttgc agaagatcca agcaacagta tacgatgggg
    38041 caattatttt attccatgat atctatcctg aaacgattcg tgccgttcct caagtgatcg
    38101 attatctgaa agagcaaggg tatcgcatca cgacagttgg ggatttatta gggcatccaa
    38161 cggctgtcga gaactattat ggcagaaacg atcatcggcc agttcagtaa gtgagacaag
    38221 tatctttaat aaataacaca ttttaataag tagttgaaca cataactacc ttacttgcaa
    38281 aggcttaaca atatctatac aggtacaaca aaaaactgtc caccaatttt ctttggcgga
    38341 cagttttcac ttaaaaataa agaagcaact attcgtaaat tatgctaaaa tagcagtaga
    38401 acgcgtcctg agggaatcga acccccgtct caagaaccgg aatcttacgt gatatccact
    38461 acactaagga cgcaagcact gggataattg taactaaaca gataaaaaat tacaagggga
    38521 ttggacaaaa aaatgaaatt tgagcaaaat ttttcacaaa aacagcagca gacacagaaa
    38581 ctagccatga cgcaacagtt gcaacagtcc atccaagttt tacaatataa cagtgaggag
    38641 ctgttggcat tcgttgagaa tcaagcaatg gaaaatccat tggtggaagt tgttgagccg
    38701 gaatggcagc cagattacat aaaagcttct tcatcttctt atgaaggaga agagacaaat
    38761 tacctaaatc agattcctga tacaaaaggg tctttatttg attcattgat cgaacaagtc
    38821 catttgaatt accgagatac ttttttgagg aaaatcgttc tttatcttgt agaatacatc
    38881 gatttgaacg gatttttgac gattagttta gaagaagccg gaaaagagat tggagctacg
    38941 cctatccaaa tgctcgatgc gttgactctg attcagcaat tagaaccagc tggagtaggt
    39001 gcacgtagtt tgcaagaatg tctcatgctt caaacagaac gagatgatta tgcgccggaa
    39061 ttagcttata tcgtgttgga agaatgtttt gaggaactgg tggagcgaaa atggaaagaa
    39121 atcgcacaac gtttttctgt tgatctacat gctgttcagc agatattcga ctatttacaa
    39181 acgttgagtc caagccctgg ccggattttc gaccgtagca gcgaattgta cattattcct
    39241 gatgtccggg tattagtgga cgacgataaa aatgtacaag ttatctcaaa ccgaaaaaat
    39301 cagccaaata tacgctttca agagagttac ttcaaacaaa tgtcacaaca agcagataaa
    39361 gaaactgaaa attatttaaa agaacggaaa caggaattcg aatggttgaa gaaaacgatc
    39421 ctacaacgtg gggatacaat tttgcgggtt gctcaagtca ttgtttcccg gcaaaaagct
    39481 ttctttatcg acaaggaacg tccaatcaag cctcttacgt taaaggaagt tgcaactgag
    39541 atagatgtgc atgaatccac ggtcagtcgt gcagtcaacg ggaaatattt ggaaacagac
    39601 ttcggtgtat ttgaattaaa aaaatttttc actacacgaa ttcctacgaa tagtacagaa
    39661 cagacagaag acctttcagc agatacagcg aagaaaaagc tgcaggaatt agtcgatcaa
    39721 gaagacaaaa acaagccgtt gtctgaccag aaattggttg aattgctgaa aaaagatgag
    39781 atagcgatct caagacgaac agtagcaaaa tatcgtgatt tattaggaat cccgagttca
    39841 tcaaaaagaa aacgttatga taactaatca gtcaaaagac tagaaaaagt atttcacttt
    39901 ttctagtctt tttagttgaa aaacgagagc aaaactgtta gacttacagt cgtgaggttg
    39961 agatttccct ttattgatgt gaaattcgaa tagttaattt ctttttttat cgtatatggg
    40021 tcgttttaag tctacattgg acgtaaagtg tccaactaag gagatcgcta tgctggatga
    40081 aataaaaatg attgaatctg ttgcaccaga tattatcgaa gtgttgcaag aacgctataa
    40141 aattttacga aatatctatt ggatgcagcc gattgggcgt cgaagtttat cggaaagtat
    40201 ggggatcaca gaacgagtct tacgaacaga aacagacctt ttgaaaaatc tgaatttgat
    40261 cgacacctca aaaagcggta tgacgctgac aactaagggc gaagaagttt atcaaagcct
    40321 tgaaaacttc atggatcagc ttttaggtac gcatcaaacc gaacaacagt tggcagaata
    40381 ttttggtaac caacgctgta tcgttgtttc aggaaacagc gaagagcaga ccaaagtggc
    40441 tgatgcattc ggcgaagcgc tgagcgaagc cttagaccga ctacttccag aaggcgagaa
    40501 tatcatcgct gtgatgggag gaactactat ggctgtggta gccgaacaat tgtctaatct
    40561 ggaaaataag aaacggcata acctgtttgt ccctgcaaga ggcgggattg gtgaagcgat
    40621 aactgtacag gcaaattctg tcagtgcaag aatggctgct aaagcaaacg gtaaccaccg
    40681 cgcactttat gttccggaac aattaagtct ggcaacttac aattctttac tcaatgagcc
    40741 atctatccaa gaagtcttaa acttgattag tgaagcgaat tgtgttattc atagtattgg
    40801 gcgtgcatta cacatggcag cacgtcgtaa gatgactgaa aaagaattag tcatgctgaa
    40861 acaagcaaat gctgttgcgg aatcttttgg ctactttttc aatgaaaaag gtgaagtcgt
    40921 ttataaggtc cctagaatcg gcatagaatt gcaagatttg gaaaaagtcc cgatcatcat
    40981 ggcaatcgcg ggcggaaaat caaaagctaa agcaattcga gcttatatga aaaatgcacc
    41041 aaaacaaacg tggctcatca ctgatgaagc tgctgcaaat gagattttaa aaggggtaac
    41101 cctttaaaat aaatattttt ttgattttca taaggaggaa atcttaaatg acagttaaag
    41161 taggtattaa tggttttgga cgtattggac gtctagcatt ccgtcgtatc caagatgtag
    41221 atggaatcga agtagtagca atcaacgact tgacagatgc taaaatgttg gcacacttgt
    41281 taaaatacga cacaactcaa ggacgtttca acggaacagt tgaagttcat gaaggttcat
    41341 tcaacgtaaa cggaaaagaa gttaaagtat tagctaaccg caacccagaa gaattaccat
    41401 ggggcgaact aggcgtagat atcgttctag aatgtactgg tttcttcact tctaaatcag
    41461 cagctgaaaa acatttaaca gctggtgcta aacgcgttgt tatctctgct cctggcggaa
    41521 acgatgttcc aacaatcgtt tataacacaa accacgaaac attaactggt aaagaaacag
    41581 ttatctcagg tgcttcatgt actactaact gtttagctcc tatggctaaa acattgaacg
    41641 acaaatttgg tgttgttgaa ggattaatga caactatcca cgcttacaca ggtgaccaaa
    41701 tgactctaga cggacctcat cctaaaggtg acttccgccg tgcacgcgct gctgctgcaa
    41761 acatcgttcc taactcaaca ggtgctgcta aagctatcgg tttagtaatt cccgaattga
    41821 acggtaaatt agacggagct gctcaacgtg ttcctgtacc aacaggttca ttaacagaat
    41881 tagtaacagt tcttgaaaaa gaagtaactg ttgacgaaat caatgcagca atgaaagaag
    41941 cttcaaacga atcttacgga tacaacacag acgaaatcgt ttcttcagat atcgttggta
    42001 tgacttacgg ttcattattt gatgctacac aaactaaagt aatgacagtt ggcgacaaac
    42061 aattagttaa aactgttgct tggtacgaca acgaaatgtc atacactgca caattagtac
    42121 gtactttaga atacttcgct aacttataag atagacaaac gtacaagtgt aaattataga
    42181 catgtacatt taaaagcggg gaagcaatcg cgcttcttcc gctttttttg ataataagtt
    42241 tattcaggag gaaataaaat ggctaagaaa acagtgaaag atatcgattt aaaagacaaa
    42301 aaagttcttg tccgtgttga cttcaacgtt cctttgaaag acggcgtgat cactgacgac
    42361 actcgtatca aagcagcatt gccaacaatc aactacgttc tagaacaagg cggaaaagca
    42421 atccttttct ctcaccttgg acgtgtaaaa acagaagaag ataaagaagg aaaatcttta
    42481 gctccagttg caaaacgtct aggcgaatta ttaggtaaag aagtaacatt cgtacctgaa
    42541 actcgcggag aacaattaga agaagcaatc cgcaacatga atgacggcga cgttgtcgta
    42601 ttcgaaaata cacgatttga agatattgac ggtaaaaaag aaagcaaaaa tgatacagaa
    42661 ctaggtaaat actgggcttc attaggcgat gtatttgtta acgatgcttt cggtacagct
    42721 caccgtgcac atgcttctaa cgtaggtatc gcttcaactg gtatcccaac agttgctgga
    42781 ttcttgatgg aaaaagaaat caagttcatc ggtgaagcag tagaagaacc aaaacgacca
    42841 atgattgcaa tccttggtgg cgcaaaagtt tctgataaaa tcggcgtaat cgaaaacttg
    42901 attcctaaag cagataaaat cttgatcggt ggcggaatga cttacacatt ctacgaagca
    42961 aaaggaatca agatcggtaa ctctctagta gaagctgata aagtggaact agcaaaagaa
    43021 ttaatcgaaa aagcaggcga caaacttgtc ttgccaatcg acaatgtctg tgcaccagaa
    43081 ttttcaaatg atgttgaaac acaagtaatc gaaggagaca ttcctgatgg tttgatggct
    43141 ttagacatcg gcccagcatc agtaaaatta tttgctgata cattacaagg tgcaaaaaca
    43201 gttgtttgga acggacctat gggtgtattt gaaatgagta actttgctaa aggtacaatc
    43261 ggtgtttgtg aagcaatcgc taacttagaa ggcgcaacaa caatcatcgg tggcggagac
    43321 tcagccgcag cagcagaaca attaggattt gctgacaaat tcacacacat ctcaacaggt
    43381 ggcggcgcaa gcttggaatt gcttgaaggt aaagaattac caggactagc agcaatcaac
    43441 gataaataaa cgaccaagtt tgctcaattc tgacgagtaa tcgaacaaaa ggtgaaggga
    43501 gttttcatga ctccctagcc atttttcaat aaattaagga gtgtgttcct caatgcgtaa
    43561 acctattatc gcaggtaact ggaaaatgaa caaaactgca tcagaagcaa aagaatttgc
    43621 tgaagcagta aaaaacaaaa tcccttcaaa tgacaaagtt gattcagtca tcggatctcc
    43681 tgcattattc ttacaagaat taatgacatc agctgaaggt acagaactaa aaatctcagc
    43741 acaaaactgc tactgggaaa actcaggtgc gttcactggt gaaacttcac cagcagctct
    43801 tgctgatcta ggtgttcatt atgtgatcat cggacattca gaacgtcgtg aatatttcca
    43861 tgaaacagac gaagacatca ataaaaaagc gaaagctatc tttgcaaatg gtatgacacc
    43921 aatcctatgc tgcggcgaat ctttagaaac ctatgaagca ggcaaaactg ctgaatggat
    43981 cgaaggacaa attacagctg gtttagctga tctttcagct gaacaggtgt caaacatggt
    44041 tattgcttat gaaccaatct gggcaatcgg tactggtaaa tcagctgacg cacaaatcgc
    44101 tgacgaaatt tgtggagttg tacgtcaaac agttgaaaaa ctttatggaa aagaagtatc
    44161 agaagcagtt cgtatccaat acggcggttc tgtaaaacca gaaaatattg ctgaatacat
    44221 ggcaaaagaa aatgttgacg gtgctttagt cggtggcgca agcttgcaag cagattcatt
    44281 cttgtcattg ttagacgctg taaaataatt gttgaaaatt tgcgaaaaat gcaagaaatg
    44341 tttgcactaa tgagcaaaat taactaaaat cgtatatgag ggaaatccct taggaaaaaa
    44401 caaactcaaa ggagagacaa aacatgtcaa ttattactga tgtttacgct cgcgagatct
    44461 tagactcacg tggtaaccca acaatcgaag tagaagtata cacagaaagc ggagcttttg
    44521 gccgcggaat ggttccttca ggtgcttcaa ctggtgaata cgaagcagtt gaattacgtg
    44581 acggagacaa agctcgttat ggcggtaaag gtgtaactaa agctgtcgac aacgtaaaca
    44641 acatcattgc tgaagcaatc attggctacg atgttcgtga ccaaatggct atcgacaaag
    44701 ctatgatcgc tttagacgga actcctaaca aaggtaaatt aggtgcgaac gctattttag
    44761 gtgtttctat cgctgttgca cgtgcagctg ctgactacct agaagtacct ttataccact
    44821 acctaggcgg attcaacaca aaagtattgc caacaccaat gatgaacatc atcaacggcg
    44881 gatcacatgc tgataactca atcgacttcc aagaattcat gatcatgcct gttggcgctc
    44941 caacattcaa agaagctcta cgtatgggtg ctgaagtatt ccacgcatta gcttcaatct
    45001 tgaaagctcg cggattagca acttctgttg gtgacgaagg tggatttgct ccaaaccttg
    45061 gttcaaacga agaaggtttt gaagtaatca tcgaagcaat cgaaaaagct ggctatgtac
    45121 ctggtaaaga cgttgttctt gctatggatg ctgcttcttc agaattctac gacaaagaaa
    45181 aaggtgttta cgtactagct gactcaggcg aaggcgaaaa aacaactgac gaaatgatca
    45241 aattctacga agaattagtt tctaaatatc caatcatctc aatcgaagat ggattagacg
    45301 aaaacgactg ggacggattc aagaaattaa ctgacgtatt aggcgacaaa gttcaattag
    45361 ttggtgacga cttgttcgta acaaacactc aaaaattatc tgaaggtatc gaaaaaggaa
    45421 ttgctaactc aatccttatc aaagtgaacc aaatcggtac attaacagaa actttcgaag
    45481 ctatcgaaat ggctaaagaa gctggctaca cagcagttgt atctcaccgt tctggtgaaa
    45541 cagaagattc aacaatctct gatatcgctg ttgcaacaaa cgctggccaa atcaaaactg
    45601 gttctctatc acgtactgac cgtattgcta aatacaacca attactacgt atcgaagacc
    45661 aacttggtga agttgcagaa tacaaaggtt tgaaatcttt ctacaactta aaaaacaaat
    45721 aattcttttc taatgaagat acatgatcga ctattgaaag atagtcgagt atgatcactt
    45781 agttaagtaa tcgaactctc tacttgctga aatatcagca ggtagagagt ttttttgcaa
    45841 ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc cttgaaaaag
    45901 gaaagctaac aataactagc atcatataag agcttttaag gatagaacag tagaatagga
    45961 atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc atatttttca
    46021 taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa ttcgagcaca
    46081 ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag aagaaaaaat
    46141 cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag gtgaagtagc
    46201 agcctatttg aataagcttt tggcaaagca tgacataaca ggagagattg tttcttacag
    46261 agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa aagtgttagg
    46321 cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga cctatgcacc
    46381 ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag atatgaagag
    46441 tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa aaccatttaa
    46501 cggaacagtc aaattattag ccactgtcgg agaaaaagtg ggtgaactag gtggggaaca
    46561 gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag agccaaccaa
    46621 ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct cgcacggaaa
    46681 agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc taaatgaatt
    46741 cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga atcctgtcct
    46801 aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca acagcatccc
    46861 aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa atgataaaat
    46921 cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact atcatttgga
    46981 attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc ctttgattca
    47041 ttgcattcag caacaattca gccagccatt acctttagtt ggagcggcag caacaacgga
    47101 tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg ggcctggtgt
    47161 cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt tggatatgat
    47221 cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta at
//
LOCUS       DADVXB010000005        44819 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.005, whole genome shotgun sequence.
ACCESSION   DADVXB010000005 DADVXB010000000
VERSION     DADVXB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.005"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(43..1083)
                     /locus_tag="KB902_000184"
     CDS             complement(43..1083)
                     /locus_tag="KB902_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6807042.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(1360..3162)
                     /locus_tag="KB902_000185"
     CDS             complement(1360..3162)
                     /locus_tag="KB902_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807043.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(3176..3928)
                     /locus_tag="KB902_000186"
     CDS             complement(3176..3928)
                     /locus_tag="KB902_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807044.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(3937..4299)
                     /locus_tag="KB902_000187"
     CDS             complement(3937..4299)
                     /locus_tag="KB902_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6807045.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(4475..5347)
                     /locus_tag="KB902_000188"
     CDS             complement(4475..5347)
                     /locus_tag="KB902_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6807046.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(5398..5886)
                     /locus_tag="KB902_000189"
     CDS             complement(5398..5886)
                     /locus_tag="KB902_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6807047.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(6024..6815)
                     /locus_tag="KB902_000190"
     CDS             complement(6024..6815)
                     /locus_tag="KB902_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBB6807048.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(6870..7478)
                     /locus_tag="KB902_000191"
     CDS             complement(6870..7478)
                     /locus_tag="KB902_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBB6807049.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(7471..7788)
                     /locus_tag="KB902_000192"
     CDS             complement(7471..7788)
                     /locus_tag="KB902_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6807050.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(7944..8672)
                     /locus_tag="KB902_000193"
     CDS             complement(7944..8672)
                     /locus_tag="KB902_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBB6807051.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            8831..9712
                     /locus_tag="KB902_000194"
     CDS             8831..9712
                     /locus_tag="KB902_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6807052.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(9949..10992)
                     /locus_tag="KB902_000195"
     CDS             complement(9949..10992)
                     /locus_tag="KB902_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6807053.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(10995..11663)
                     /locus_tag="KB902_000196"
     CDS             complement(10995..11663)
                     /locus_tag="KB902_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6807054.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            11805..14141
                     /locus_tag="KB902_000197"
     CDS             11805..14141
                     /locus_tag="KB902_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807055.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(14256..14567)
                     /locus_tag="KB902_000198"
     CDS             complement(14256..14567)
                     /locus_tag="KB902_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807056.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            14748..16223
                     /locus_tag="KB902_000199"
     CDS             14748..16223
                     /locus_tag="KB902_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBB6807057.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            16270..16854
                     /locus_tag="KB902_000200"
     CDS             16270..16854
                     /locus_tag="KB902_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBB6807058.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            16856..17275
                     /locus_tag="KB902_000201"
     CDS             16856..17275
                     /locus_tag="KB902_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBB6807059.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(17556..17840)
                     /locus_tag="KB902_000202"
     CDS             complement(17556..17840)
                     /locus_tag="KB902_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBB6807060.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18192..18902)
                     /locus_tag="KB902_000203"
     CDS             complement(18192..18902)
                     /locus_tag="KB902_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBB6807061.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(18899..20371)
                     /locus_tag="KB902_000204"
     CDS             complement(18899..20371)
                     /locus_tag="KB902_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6807062.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            20509..20982
                     /locus_tag="KB902_000205"
     CDS             20509..20982
                     /locus_tag="KB902_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6807063.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(21135..21686)
                     /locus_tag="KB902_000206"
     CDS             complement(21135..21686)
                     /locus_tag="KB902_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6807064.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            21791..22321
                     /locus_tag="KB902_000207"
     CDS             21791..22321
                     /locus_tag="KB902_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBB6807065.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(22804..23247)
                     /locus_tag="KB902_000208"
     CDS             complement(22804..23247)
                     /locus_tag="KB902_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6807066.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(23263..24423)
                     /locus_tag="KB902_000209"
     CDS             complement(23263..24423)
                     /locus_tag="KB902_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6807067.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            24930..26630
                     /locus_tag="KB902_000210"
     CDS             24930..26630
                     /locus_tag="KB902_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807068.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(26732..27565)
                     /locus_tag="KB902_000211"
     CDS             complement(26732..27565)
                     /locus_tag="KB902_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBB6807069.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(27869..30034)
                     /locus_tag="KB902_000212"
     CDS             complement(27869..30034)
                     /locus_tag="KB902_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6807070.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            30294..32588
                     /locus_tag="KB902_000213"
     CDS             30294..32588
                     /locus_tag="KB902_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6807071.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            32581..33246
                     /gene="pgmB"
                     /locus_tag="KB902_000214"
     CDS             32581..33246
                     /gene="pgmB"
                     /locus_tag="KB902_000214"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6807072.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            33239..34246
                     /locus_tag="KB902_000215"
     CDS             33239..34246
                     /locus_tag="KB902_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6807073.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            34268..35287
                     /locus_tag="KB902_000216"
     CDS             34268..35287
                     /locus_tag="KB902_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807074.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(35568..36935)
                     /gene="nhaC"
                     /locus_tag="KB902_000217"
     CDS             complement(35568..36935)
                     /gene="nhaC"
                     /locus_tag="KB902_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6807075.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKEITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(37044..38465)
                     /locus_tag="KB902_000218"
     CDS             complement(37044..38465)
                     /locus_tag="KB902_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6807076.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(38708..40585)
                     /gene="tdc"
                     /locus_tag="KB902_000219"
     CDS             complement(38708..40585)
                     /gene="tdc"
                     /locus_tag="KB902_000219"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6807077.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(40876..42132)
                     /locus_tag="KB902_000220"
     CDS             complement(40876..42132)
                     /locus_tag="KB902_000220"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBB6807078.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(42244..42449)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            42712..44013
                     /locus_tag="KB902_000221"
     CDS             42712..44013
                     /locus_tag="KB902_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6807079.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(44082..44681)
                     /locus_tag="KB902_000222"
     CDS             complement(44082..44681)
                     /locus_tag="KB902_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6807080.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT        13651 a         9238 c         7926 g        14004 t
ORIGIN      
        1 aaaaggggat gtgacactgt cacactccct ttttaattta ttctatttct ttatatttat
       61 tttgtattcc gttacaaact cgcgtacttg gttaggttcc agagtgacat ctccaaaact
      121 ttcaagtcgc tccgctcctg gcagttcttg agtctcaaat gtgataccgc catgatttac
      181 taatttattc ccgcgcattt ccggtccatc ttctccaaaa tttgctgtaa aaatcacgat
      241 tcctgaagca tctgttttta cttggatcga tactttttca tctgggcttg tcaattccgc
      301 agcatttagt aaaccagatt gttttttcaa caaaaatgga tgatcgatgc cgcccactat
      361 cattgattgg cgaaaatcac tggcaaagac ctcacctaat tttttaggac gttggaagtc
      421 aaatgctgtg ccacttactg aaactacttc tcctgtaggc gttgtatctt tattgagcgt
      481 agcaaataat cggctattca accaaagtat atgttcgtcg attgactgtg ctggatcacc
      541 ggttaaattg aaatagacat gatttgtagg attgaatact gttttgcggt cactgatccc
      601 ttggaccgtc actcgccatg tatcatcgtt cgtcagcgta taccgtactt ctacatctaa
      661 agttccagga aatccgtttt ccatatctgg gctagtctga tagaaaatga ccgatgcttc
      721 gttttcacca ttgatgactg tataatgcca ctgcttggct tcaaagctag gtgcaccacc
      781 atgtaaacaa tgaccagtgt ccgggtctgt ttttacttcg aacgtttcat catctaattt
      841 gaatgtgcca ttcgtaatcc gtccagccat acgtccgatt gaagcaccga tataagggtc
      901 tttttctaga tattcttttg cttcatcaaa acctaagatc aactctcgtt tttcattatc
      961 gattattgtt tgaaaatgaa caacccgtgc cccaagatca ctgacagaca aagatgtccc
     1021 attttgattc gtgatcgtaa tcaagtgata gttttcgcca aaattttgtt cattgatttc
     1081 catgttcctt gcaccctctt ttctttcatt tgcactgatt ccagtataca tggaaaccgt
     1141 tttcttaaca gcttattccg tgagtaacga gaaaaaattt actatattct aataaaagac
     1201 cgtgaaaaaa aggttgtgac aaaaatattg tcacaacctc tttttccgaa caaacggtgt
     1261 tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaatatgag gagctatttt
     1321 tgcttggctg ttcttattac ttgatgcagg acagcttttt cacaatctct ttttcaatac
     1381 gattccagta tataaccatg tcgtcagtac atagtagatg aaatacaata cgaagaatat
     1441 cgtaaacgga acccaaatat ctttgtatgg attttgcatg aatagaccaa acatttgtaa
     1501 tccgaataag acatggacta cacctaagat tcctggtgct aagaataaca cgcctacttc
     1561 tctacggatc gattgtttaa gcaacccgcg tcgtgttcct atcttttcaa gcatttcata
     1621 acgagcaatg tcactcttgc ttcctgacaa gatcttgaac atcaaacagc tagcaagcat
     1681 ggtcaagaaa gctaaaccta ggaagaatcc cataaattca aaaccagaga atagaccatt
     1741 atacacttca tacatttcat atttctggtt gctgtactct actttttgca aagatggatt
     1801 gttcatttta ttttgagcaa caagtgtttc gattggtttc aggtttgctt ggaagtcttt
     1861 tacctgaact agctgtaaag tggattgtgg caagttcagt tgatcaaatt ctgattgact
     1921 gactaccttg atttcttttt cttgctgttc cggcaattca tagcttcgaa gttcctcttg
     1981 tacagtcagt tcattcattt ttttagcagg aactttttct ttcgtgatct tcggcggtgt
     2041 tccatcttca tgttttatca tgatcaatgg ttgagccgca aattcacttg cattatagta
     2101 aatcgttccc gcatcttctt tttgagtata agaagcagaa agtgttggtg aaagttcttt
     2161 gattttttgc tgatcttctg cccgaggatt attcatcact agatcatatc cagaattgtt
     2221 ttctgtcaag tctgcaattt catttttaaa acctaatcct accgtcaaag cgcccagtgc
     2281 caaggcaaac agcatagcga ccattgagag catttgtgta tattcacgaa tacgaaagtt
     2341 taactgtgac aatgtgaaat tgttcaattt tttcaatgaa atctgttctg atttctttag
     2401 taatgataaa aagaaaatga tcacagaatg gaaaatgaaa taagttccta atacgatcgt
     2461 aactaaggct acccctatac caaagacttg ataggtcccc acgtgtttca tcatatagta
     2521 accgcagcct agaaaagcaa ttcccagtac tacttcaagg aaaaacaaga atttatgctg
     2581 cttgattctt gttggtgtct gatccgcacg aatcaatgct aaaatcggtt ttttgacaat
     2641 cgaaaaagca ttgacaacag cagctaataa aaacaaaaca gcaaaaaaca aaacagtgat
     2701 caacaacccg tgaatactaa aaggtgtaaa atgcgaaata ttgagatcta actgatccac
     2761 taataatcgg tggacgatac ttgtcaatcc tacaccgaca gctgaaccca ctaaagtagc
     2821 tgcgatccct actaagaatg tttcagaaaa aatcatctgt gcgatttttc tgccttttgc
     2881 tcccagcatc ataaacattg catagtcttt ttgccgcatc gtcatcaaaa aggaatttgc
     2941 atataaaata taaacgaatg tgatgatccc tagtaaaaca gaaccgaatc ggaaaatgat
     3001 aactgtagcc gcaacgatcg tattactttt caaaaaagct tcgttgcttg ccattgattc
     3061 aaacatgtaa aaaatagcag atgccataac taatcctgag aataacacca agtagtctct
     3121 taaacggctc ttgatcccag taagtgataa tttccaaagc atagtcaatc tccccctact
     3181 gttccaagtt tccaagaata gatagtattt ctcgatagaa ggaatcacgg ctttgatctc
     3241 cacgtttcac ttcttgatgg ataccgccat ccttgatgaa taaaatacgt tggcaataac
     3301 ttgcagaaaa cggatcatgc gtcacaagaa gaatcgatac atgatctttt gtattcaatt
     3361 cgtccatcgt atctaaaaga tcccgggcac ttttggaatc cagcgcacct gtaggctcat
     3421 cccctaatag aatcgttggt tgtgtgatca atgcacgtgc ggcggcgacc cgttgttttt
     3481 gtccaccgga aatctcagaa ggatagcttt ccaaaatatg agagatggat aaacgttctg
     3541 caattttttg gacacgttgc ttgatttctt ttggtctgac gccttgtaaa gaaagaggaa
     3601 cagcgatatt ttcttgtgct gtcaagcttt ctaataaatt gaaatcttgg aaaataaagc
     3661 caatctcatt cgcacgaaaa tctgctagtt gatttccttt taatgtggtc acatcttttt
     3721 gattgattcg gatatgccca tctgttggtt tatctaatgt ggataaaata ttcaaaagtg
     3781 tcgacttacc agaaccagaa gcgcccatga tcccaataaa ttcgcctttt tctacatcga
     3841 agctgatgcc gcttaatgct tgcgtctttt tctcattgtt ttttccgtat acttttgtta
     3901 cattctgtac ttcgactatt ttgttcattt ctttccctac cctttaatta gtttttccag
     3961 tgctgttttc ggcacgtctt ttttttcgac ttcttcatac gaagtgacac ctttattttt
     4021 gttccaggtg atttttaaat atgctccttt acgaagcggt cgagtcaatt gtcccttgaa
     4081 gtccagttct ttttccttac cctctttcgt atagccaggc aggatatatc tatagttgac
     4141 tgtttcttgt ccagagtctg attttgaaac tgtttttgta ccatctgtcg taatttgtac
     4201 atagtattct tctccaccca taactacgta atctgcgatt ttcacccctg caagtaccac
     4261 aacgatgaaa acaagtagac cgatcagaag ttttttcact ttttcccctt ctctcttact
     4321 ttatatactg attatagaaa aaagcgaaca attctgcctt cgaatcaact atcattcttc
     4381 tttcaatttt gtcattttct ttaaaacaac taaaaaaaga gttcaagaca ataatccgtc
     4441 ctaaactcct tcttcctatc ttacaaaaag tatgtcactt acggtctttc atgtcgcctg
     4501 tattgataac aggttgcgtt cctttgtctg taatgattga gacaagtaaa ttattgatca
     4561 attggacttt ccgatcatcg gtgaaattga tttcttgtcc atcttcgatt tgctctaagg
     4621 ccatttgagt gattgtgaca gctccttcaa caatggtttg tcgagcagac aaaatggctt
     4681 ttgcttgttg acgttggagc atggcactag cgatttctgt tgcataggct aaatggttca
     4741 agcgtgtttc gattacttcg acacctgcta ctgctaaacg ctcttgcagc tctttttgca
     4801 actcgtcaga cactgccgtc gtgtttcctc gaagcgtcaa atcattctca ttgaatgtat
     4861 catacgggta ttggctagcg atatgccgaa tggctgtctc actttggatt tctacaaaat
     4921 cttgataata cgctacatcg aataatgcct ttgctgtatc aacgacttta aagactacta
     4981 ctgctgagat ttcgatgggg tttccatcca aatcattgac ttttaaaaca gaactattga
     5041 aattccgaac tttcaacgaa acagtcattt tttgtgccaa aggtatcgta aggaaaaagc
     5101 cattttctcg aatcgtacct aaatattgtc caaaaaacaa aattactttt gcttgattag
     5161 gactgactac agttgccgaa cttaacaaca ataacgtgat caaccaaaga aaaatactta
     5221 aaaaaagtgc ccaaactttc gcttgccaca tacctaaata gaagaaaaac aatccaacta
     5281 aagctaatac gaccaatccg acaatccctg cataaccatt gatataaaat gctctttttt
     5341 ctctcatgct acttcctgcg ctcctttatc cttcaataaa tatctaatgt tactttttta
     5401 attttttttt cgaatacgcg ccattacacc ttctagttct aactctttgt cttcagtgat
     5461 gtaccaaccg cttgcctgtg tccctccggc tgcctgcggt aaataatcca attttgttcg
     5521 aacccagtgc ttttcttctg taaaatagtc ttctaccaag acctctagat ccatccctgc
     5581 tgaaagaggc aaatcttccc gaacagattt aaagataaat cgttccttct tcccatcata
     5641 cttcaatatt cctgtatcga taatcggtaa agaataataa tccagctctt tcttcaccgt
     5701 caataaatgt ttgaaaactt catggtacac ttgctctaat tggcgacctt ctgaattgtt
     5761 cgggtaatta accatcactt tttctttgtc tggatcatag aaggtttggc ttagttgagt
     5821 gatataagta tgtaatcttt ccatttctgt ttttaacttt tctctttgac cttcttctac
     5881 cttcatatac tctttcaccc tgttttcttt ttagatattt tctttcttat tttactatag
     5941 ttatgtgcgt taagcgatga aaaacagcaa agattggaag gatctttgct gttttttctt
     6001 aaaatatcca gttgagtaca ggatcaatct gtttcattgt cctcttgatc cgtcgtaata
     6061 ttgatcgatg tgtctttagc agtgatcttt agctttttct gtccttgttc taacaaagta
     6121 tttgttattg gctggtagtc tttttcaata taagattcac cagacgtttg gatagtatag
     6181 ccactgtttt ccatctcatg caaagataaa ttgccaccgt ttaggatgac ttttccttct
     6241 ttgctgatca aactgtcttc tagatggaag ttgctgtttt cacctgtgac gatcaagtta
     6301 tccacattgg cctcatctaa tcgaagtgag cctaattcat ctttcgcagt tattgttcct
     6361 cctgtaaatt cattgaacga tacccagcca tcatgtgtct tagtattcac ttttttgatt
     6421 gatacttcgt tgatatcaat tgcactatta ttcccttcga ttgtcaattc agataattca
     6481 tgatctgcag ggacaacaat agtgatttgt gcacttgtgt cttctaaact aatgattgca
     6541 cctgttgatt ttttgactgc attcacagtc aacacgccat ttttctcctt tatttctggc
     6601 ttttctgtct tatcataagt cgtttttatc tcaaaatcca atccgcgtat gaccgaaact
     6661 gtttgatttt ctgcatggat gacgattttg tttgcatcct tgattttttt tgtctcagta
     6721 accatatcga tcaaccgagg accattatcc caagtcagac tcttttgagc gcctaatgta
     6781 taagttgcac ctgctaggag gccaccagta agcatcagac caataccggt aatcaaaaaa
     6841 tgtttcaatc tcaatttatg tgtcctcctt caaacgcccg ctgaatgcag atctcttttt
     6901 gtaataaaac gtcgtcccat ccatttaaca aagttcatca tgacataaaa aagccctttt
     6961 gttcctttca gcaacagtgg cgaaataaat actgcgcttc ctgtggcgaa cagaccgaca
     7021 ccgataaaga ataatccact cagaatcgat tgtccaaaca cactgattcc tgagatgatc
     7081 atgaataggc caacacctaa gatactgata cataaaacat agatactaaa aatgagcgct
     7141 agtaaagcaa ccaatagtcc cccaataacc aatataaacc ccagtgctag tggaatgagg
     7201 acaggagaag caaataaacc gataatgatt aaccaaatca ggcgaatttg tctttttgga
     7261 tttttcacta actcgttttc tgcttgttct tcttctgaaa agtaactgat ttttaatttt
     7321 aaggcaaact gctttggtgt accatattca tcaatgatct gatctaatgt ttttccagaa
     7381 tctaaaaaat attcctcata atactggatc aaatcaaaac gatcgtcttc aggaatttct
     7441 tgaagatgat ccacaacttc attcaaatat tcattcattt gtgctctcct ccaataaccg
     7501 gtctaaagaa tctcgaaaaa caatccattc atcaataatt tcttctaaat gacgacttcc
     7561 cattggtgtc aacgagtaat atcgacggtt tctgccttca aaaggttcat cataggtctc
     7621 aagatatcct tcttttttca atcttctcaa aaccggatat agtgtagatt cactgacaga
     7681 gagactttct tgtacgattt ttgttaaggc atacccatac atatcttcct tgcttaatgc
     7741 tgctagcaca gtaccatcaa gaagaacagt tggaatctgg atgtgcatta cgtcaccttc
     7801 tattctcaag tgtaatattt tatttcaatc tatattatac aacatataat atagtttcaa
     7861 aatcagtttg tcaaatacaa aaaaactgac taaaagattt gatccttttt agtcagcaaa
     7921 aaatggcttc tctttgattt ttattataac agtggcataa tccaatttgt ccacatccag
     7981 ctcagtggca taataacgat cattgcaggt atcatgtcag ctactgggaa cattttcacg
     8041 ttgatcattc taaaaccggt agcgaccatc aagaatccgc cgcaagcttt aaaatctaag
     8101 atcatgtctg gtgtagtcaa tggataaata aattttgcca ataagaacaa aatataaaaa
     8161 ataatgaatt ggggaattgc tatcacagaa acgacatacc ctaaattaca cgcaaaaata
     8221 gctgctgtga aaaaatcaag gacagattta gaaatcaaaa tcgtactgtc tcctgtcatc
     8281 ccagaatcta aacttccata gatccccgta ccacttgcac aaaatagaac aatgaccgtc
     8341 actaatgtgc tgataaattc atcgtgggtc ataccaagct tttcactagg gaagatttta
     8401 gaaataggta cttgcatcag cgcagccccc ttatttatcc cattacctaa atgaacaatc
     8461 aaaccaatcg ctgttcctat cactaaagca aaaataacag ccggcatatt tttcatcggc
     8521 gcaatggaat agattcccat ccccatcgaa cacacaccaa aaaccatcgt cagctgtgct
     8581 ttaaaatgtt cacttaattt atttcctact aatccgccaa ttagtccgcc aaacaaaacg
     8641 gaacctacat tgatcaaaac tccagttggc atcaaaaaac tcctctcttt ttctacgaag
     8701 cgaaaaaaat cagaaaaatt tctgtaatta ttgctttcgc tgcaagaaag attgtaacag
     8761 acagagaaga ttacaccaat tcattttttg tgttaaagta ttctttattg gaataagtag
     8821 gaggaatatg atggatatcc ataaattcga agtttttctt gatttagccg aaacaatgaa
     8881 tttcaccaaa actgctgatc gacaattcac cacccaagga aatatttcta aacagattct
     8941 ttcgttagaa acagaattag acgtcaaatt attcgaacgc gcccatagaa aaatcgaatt
     9001 gaccgaagct ggaagcttat tgctcccata tgtaaaaaat gtcgtagaac aataccatgc
     9061 tatgcaagaa gtgcttgaaa cctatacgaa agacaacaat ctttcattaa atatcttaac
     9121 gataccgaca atgatcaatt ataaaggttt ttccaaaatc accgagtttt tgaaacgcca
     9181 tcctgaattt acagtccagt tgaaagaagt ggaaagtgtc gaattaactt acaatgacgc
     9241 caatgaacat agtgacacga tccactttgc tagaagtttc caggccccac caagttcgat
     9301 tgagtggttg cctactgaaa cagacgattt tgtagcagtt ctacctaaaa atcatccttt
     9361 agctagtaaa aagaaattgg atctaagcga actgaaaaag gagaactttt tgctccttgg
     9421 ccccactacg aacttgtatc aacctgtact agatctgtgt cgcgaagctg gatttgaacc
     9481 aaaaatctct tataaaggag caagaatcga cttgatcatc aatatgattg caaatgacat
     9541 ggggattgct attgttatgg aaaaaacagt caagaatcta ttaaaagaaa atactgtgat
     9601 tctccctatt tctccaacaa cagagagtta tcttgcattt actcgtaaag tcggtgagca
     9661 ttctttggct tcagatacat tttgggagta tttaaatcaa gaagaaaact aagccctaca
     9721 ttttctgtcc atctatccac ccaaaaaaag agagcgacgc atgactttcg ctctctttct
     9781 tgcatcatgt ccttgtttca atgacacctc taacatttct cgtagttcaa taagaaagca
     9841 gcgattttta tgccaaaaga accgtaagaa catttcccta atcacaaaaa aacgactaaa
     9901 aacccctaaa aaccttcaat agaattttta ggggttttat tctttttcct attgtttact
     9961 taaccgtatc attgctgtcg ttcctactcc ttcgatactg ctataatcaa tacgtccatc
    10021 atgcagttct agaatttttt taaccagtga aagtcctagc ccattcccag aaatttgacg
    10081 acttgtatct ccttgataaa atttttcaaa cattcgatct ctggtctctt cattcattcc
    10141 tacacctgaa tcggtcactt ccagtacaat ctctgtggct gtctcaaata gtttgatatg
    10201 aatctgtcca ttgatttgat tgtactttat ggcgttatcc atgatattca gccacacttg
    10261 gtacaaaaac tcttcattgc ctgtgtaatt tactgcagca agttcgatat ccaattctag
    10321 ctgttctttc tcccatttag gctgaaaaaa aacgattact tctctgattt gttcatctaa
    10381 tcgatactct ttcttttcca gttggatacg ctggttttcc agtttgttca attttaagat
    10441 gttctctgtt aattgtgaaa gctgcgtgat actttcgata atccgatata aaaatatttg
    10501 gcgttcttcg tcagagagat ttggggcttg taacaattga acatatcctt ggattgttgc
    10561 tagtggtgtt ttgaattcat gggatacact ggacacaaag tcattcctca gtgtctcgat
    10621 actattgagt tcttggacca taacgttgaa atctttatac agttgctgta cttctgctac
    10681 tttctgctgt tcatccattc gaatcgaaaa atctcccgtt gctaccagac tcatatttgt
    10741 ccctagcgca ctgattggat gcaggatacg ccgcccaaca aaaatcgata ttcctgtacc
    10801 cacgaccata ctgaaccccg caaagacgaa taacgggtat aacgttggtt ttccagccga
    10861 ttcagcaggc gagatagaat gtcgagacaa taagaaaata aaaccgagaa aacacagcag
    10921 tgtcactaag atcgaaatga agacaatact agcaaaatag atccataatt gtgaaaatag
    10981 cttttttttc atctttaaat aaccgcctta tagcctagtc cccgtactgt gatgatttga
    11041 aaatcttccg tcttttcaaa acgggtcctt aaacgtttga tatgtacatc gatcgttcgt
    11101 tcttctgtat tcgtatctaa tccccaaata tcatccatca actgttggcg agtgaagatc
    11161 ttgttgggat aagacagtaa tttatacaga agcagaaatt ctttttgagg cagaatcaac
    11221 gaatgctgat cttgtaacac tgtataagca tctagctcta attttgtttg tccgattatc
    11281 aagctactgc tgtaattgat ctttgaacgt cgaagcaatg cttccacacg taggatcatc
    11341 tcattgacat cgatgggttt tgtcatataa tcatctgctc ctaatttgaa cccgcgtttc
    11401 ttatcctcaa aatcggcctt tgccgtaatc attagaacag gtgtgtcaaa tctggtgcta
    11461 cgtaatgagt ctagcaagtc atagccatcc attttcggca tcatgatatc tgtaatgatt
    11521 aattctatac gtgtcgcttc tagttttttc agcgcatcct ctccattcaa tgcggtgatg
    11581 actgaaaagc ccgctcgttc caacacagaa cggtaaagca actgtaattg cggatcatct
    11641 tctactacta aaatacgatt cattgatctc cctctgtttt ttgaaaaatt tctagatttt
    11701 ttcttgtagt tcatcttcag ttaacattta tttcgtatac tacgatcatt gttctgatat
    11761 acttattagt ataccgaata tttcaatacg ggagaagggt gattatgctt caattaaaag
    11821 atataaaaaa atattataaa gtcggcgaaa ccaccaccaa agcattggat ggtgtgtctg
    11881 tcgctttcag acaaaaagaa ttcgtagcga ttttaggtcc tagtggttct ggtaaaacga
    11941 ctatgctgaa tgtgattggt ggactagata attatgattc cggtgatatg gtaatcaacg
    12001 gaaagtctac taaagacttt aaggacagtg actgggatgc ctaccgaaac aactctatcg
    12061 gtttcatttt tcaaagttac aacttgattg gtcatctagg cattattgaa aacgttgaac
    12121 ttgggatgac attaagtggt gtttctaaag acgaaaaacg aaaacgggca gaagatgcat
    12181 tgcaccgagt cggcttgaca aatcatatgc ataaaaagcc aaatcagtta tctggtggac
    12241 aaatgcagcg agtggccatc gctcgagcac tagccaatga cccagatatc cttttgtgcg
    12301 atgaaccaac cggagcgtta gatacagaaa caagtatcca gatcatggaa ttgatccaag
    12361 agttatcgaa agaaaaatta gtgatcatgg tcacacataa tcctgaactg gcccatcaat
    12421 acgcagatcg aatcattgaa ttttctgatg gtaagatctt aacagattcc catcctcaca
    12481 tcgaacgacc aaaagatgat caatttaact tacgcagaac aaagatgagt ttttggacag
    12541 cgttaaagct ttccttcaac aatatccgaa caaaaaaagg acgtactttc ttgacctcct
    12601 ttgcttccag tattgggatc atcggaatcg cgatcgttct gtccctttct tctggattcc
    12661 aaaaacaaat cgataacacg caagctgaaa cgatggcgaa atttccgatt actatttcta
    12721 aggtaacgac taaccagact cgtgacgatg ccggattggg tgcaagcaaa gcggattatc
    12781 cagacagcaa aacgattact gcaaaagtca gcgaagaaga taaagcacag cacacgaata
    12841 agattgatca aacatacgtc gattacgtaa cagacatcga tcctaactta agtaataata
    12901 tcggatttac ccgtactaca ggaatcaatc ttttacgtga tgtaaatggc aaagtacagc
    12961 ctgtcagctt ctcgaatcaa aatcctgata cggaatctct ttctttatct agtacgatgt
    13021 cagcaatgac aggtgtggga gtgtcaagtt tccctacaca gcttgacact agcaaagaaa
    13081 actttttaaa agacaattat tctttacttg ccggaagtta tccagcctca gcaacagatg
    13141 tcgtgctgat cgtagacggc aataataata ctaatatcaa cgcattgaag aatcttggat
    13201 ttgatgtgaa agaagacgaa aaacttgatt ttgatgatat cgttggtaca acattcaaat
    13261 tagtaaacaa caatacttac tatacaaaac ttccaactgg gaattttatc cctaatacag
    13321 attatgatgc gatgtatcag aatgcttctg atgaattgaa gatctcgggg atcctacgcg
    13381 tgaaatcttc ttctacaatg aatctcttat ctccaggaat cgcttatagc gatcaattaa
    13441 cgactcaaat cgtcaacgaa aacaaagaat cagaaatcgt caaagctcaa agagacagtg
    13501 gtgtaaatgt cttaactact gaaaaagttg acgaaaatgc caaacaaaca ttgcttagtt
    13561 atttaggtgg agacagcttg ccttcaagta tcatgattta tccgaacaat tttgaagaca
    13621 aagaaaagat cttggattat ctagatgatt acaataaagg caaatcagat gaagataaaa
    13681 tcatttatac tgatttagct ggaacgatga ctgaactgac tggcggattg atggatgcta
    13741 tcacttatgt ccttattgct tttgcaggga tctctttagt aacaagtatg atcatgatca
    13801 gtatcattac ttatacatct gtgattgaac ggacaaaaga aatcggtgta ctaaaagctt
    13861 taggtgcacg taaaaaagac atcactcgcg tatttgacgc agaaacgtgt attttaggta
    13921 tttcttctgg gatattaggt gtgtttattg catggctagc tacgttccct atcaatagca
    13981 tcttatacaa catgacggat ctaaaaaatg ttgctcaact aaatcctgtc catgcgatta
    14041 ttctagtgat cgtctctact atattgacga tgcttggcgg tcatcttcct gcacgaatgg
    14101 cagcgaaaaa agacgccgct atcgctttgc gtgcagaata aggttgtgac aaccacattt
    14161 agatttgagt cataagagcg ctgaaatagt agaaaacagc aagaaacgag gaagtaatat
    14221 gttccttgtt tcgcgctgtt ttttttaatt attttttata attctggtat acttttcttt
    14281 cctttgtacc acaactcttc tggcgtatac ctgtcttttc catttatgaa tactgttcca
    14341 tctgcttcaa tcgttacttc agtcccaatc cacatattac gagaaagtgc gagaagattt
    14401 tttctttttc ctcttccttt ttttccaaat tgcaaggcat cggttatctc ttctgtccaa
    14461 tgagatttca cgtattttac ttctccgttt tcaaatgtaa ctttcaaaat attcgctata
    14521 ttttccactt ttactgcttt aggaaatgac tcctccattt ttttcacttt ccttcctcca
    14581 acactaagta tgcgctttct tttagtgata agtatatcat agtttattct attatcaaaa
    14641 aaacgcatcc attccattgt agaatacttt accgaacaag ttgaattgtt ttcctctttt
    14701 tcacctttta ctatagatag gtaaagacaa ctaaggagga atctctcatg acagatcaac
    14761 cgtatgattt aagaaaagtc atcgaagaac taaaaacact tccaggtcaa tatcacgaaa
    14821 cagatattga aatcgatcct gaagcagaat tatctggtgt ttaccgttat atcggtgctg
    14881 gcggtacagt aaaacgtccg actcaagaag gaccagctat gactttcaac aatatcaaag
    14941 gtttccccgg cacacgtgtg aacatcggaa caatggctag tcgtaaacgt gtaggtgaaa
    15001 ttttgcacca tgattatcga acacttggtc gtttcttgaa agacgctgta gaaaatccaa
    15061 tcaaacctgt gaaagtagac aaagcagacg ctccagcaca agaagtcgtt catctagcta
    15121 ccgatgcaga cttcgatatt cgcaacattt tgcctgcacc tacaaatact cctgaagatg
    15181 ctggtccata catcacaatg ggtgtagtct taggatcaga tccagaaaaa acaatgagcg
    15241 atgtaacgat ccatcgtatg gttctagaag ataaagatac gatcggtatg tacatcatgc
    15301 ctggcggacg ccacattggt cacttccaaa aacaattcga agccttgaat aaaccaatgc
    15361 ctatcactat caatattggt ttagatccag caattgccat tggcacgact ttcgaaccac
    15421 ctaccactcc acttggctac aatgaactat ggtgtgcagg agctttgcgt aacgaaccta
    15481 ttcaaatcgt tgatggtata gcagtcgatg aagtgggtat tgctcgtgct gaattcatca
    15541 ttgaagcaga aatcatgcca aatgaaacaa tgcaagaaga tatcaacacg aactcaggaa
    15601 aagcaatgcc agaatttcct ggctatactg gggatgctaa tccagctgta caagtagtga
    15661 aagtcaaagc agttactcac cgaaaagaca atccaatcat gcaaacaacg attggtccca
    15721 gtgaagaaca cgtatctatg gccggtattc ctacagaagc aagtattctt gccttggtcg
    15781 ataaagctat tccaggaaaa gtagtaaatg tctacaatcc tcctgcaggt ggtggtaaat
    15841 tgatgaccat catgcaaatc cgtaaagaaa acgaagcgga tgaaggtatt cagcgtcaag
    15901 cagctattct tgctttatca gccttcaaag aattgaagac agtcatttta gtcgatgaag
    15961 atgttgatat tttcgacatg aacgatgtag tttggacttt caacactcgt ttccaaggag
    16021 ataaagatat catcgtgatc ccaggaatga ggaaccatcc attggaccca tcagaattac
    16081 cagaatataa tcctggctct attcgtttcc gtgggataag tgcaaaaact atctttgacg
    16141 gtacagttcc tttcgatatg aaagaacatt ttgtacgtgc aaaattccaa gaagtagaag
    16201 attgggaaaa atatttgaaa taatgaatga tctgcaactg ttttgacatc ataaaaagga
    16261 gtgcggaaaa tggaacaatt ggcacaacgg aagaaaaaaa tcgtgattgg tgtaagtggc
    16321 gcttcaggca ccatttatgc catcaaccta gtgaagaaac taaaagaata tccgatgata
    16381 gaaacacacg gaatcatcag tccatgggca aaacagaact taaagctgga atccgactta
    16441 tcactaactg aattcgaaag cctgtttgat taccattatt caaacaaaga tttaggtgct
    16501 gctgtcgcca gcggatcatt tttgaccgat ggaatgatca tcgtaccggc aagtatgaaa
    16561 acagtcgcag gtatctctgt tggtttaggc gacaacctga ttgcacgtgc tgctgatgta
    16621 acaatgaagg agcaacgaaa gttagtcatt gttcctcgtg aaacgccatt aaatgccatt
    16681 cacttggaaa acttgactaa attagcacga ctaggtgtgc aaatcatacc accaattcct
    16741 gctttttata atcagcctca aacgatccaa gatcttgtta atcaccatac aatgaaactt
    16801 ttggatcaat ttgaaattgt aaatgagcat tcaaaacgtt ggcagggtga ttaatatgga
    16861 aaaagaaacg atagttgaag taaccaaact aggtttcacg atccaagctg ctgttaaagt
    16921 aatcggtaaa gacttattga tcactttaac aggcggagat acaccacata tcggaacagt
    16981 cactacattt tctcgtgata cagagatgca aactgtacgt ttccctagcc acgatggtcg
    17041 gttccataaa gacgatgtct tagccgaaaa aatagctgtg atcatcaaaa ctgccgttcc
    17101 gggaagttgt acgatcactt ccggtatcca tgttgaccat atctccaatg cacaaatcaa
    17161 cgcctctttt ccgatgtcag aagagttagg ttacaagatt ttagattggt tggaaaaaat
    17221 agatttccat atcaaagaac cagtttatta taaagatggt gaaaaaccat tatgaaagaa
    17281 gaggttgtga aatcagcgtt atgacctgag tatgagagaa aaaaatggaa aaatagcttc
    17341 tcatattttg ccgtttttga gctaataccg agggacagct gattgaacgc cgtttatcaa
    17401 gaggttgtga taaagccgct tcgtttcgag tagtaagaaa aattttgtaa acatgggttt
    17461 ccacattttt gcataaattt gacttactac cgagaaactg gcttttgaac accgtttatc
    17521 aagaggttgt gacacgtctt ttgtcacaac ctcttttatt tttgcttcac tgtaactgct
    17581 acaatatcac cgatttcttt tccgatgttt ttacgaatat cttttcgtag tccaaggatg
    17641 tagcagactg aaccatctgg atttttcacg cccatattca cgatactgcc ttcatacggc
    17701 acattgtcaa aagttgcttg gactttaact cttccagcac cgaattcttt tcttatatca
    17761 tacggaaaaa taatatatgc cccgcccttg ccgacttcgg aagcatagat ttttgattca
    17821 aaagaataaa tttccctcat tttatttctc ctatttttta catctagtat agcatagcaa
    17881 aaaaaagaag gaactgtgac aaaagtcttg tcgcagttcc ttttttcgaa taaacggtgt
    17941 tctcctgcca actcctcggt cacaagtcac aatagtcaac aaacatgaga agctgttttt
    18001 tgaaattgct ccttgtgact cagagttaaa cggaaggctc acaacctctt ccttaaacgg
    18061 tgttcaaaag cttgcatcta cggcactaag cccaatcaga tgaaaaatat ggagtgctat
    18121 ttttatctga ttgttcttac tgcttgatgc agagcagctt tttcacaacc tcctacatgg
    18181 tgttcaaaat attattcgcc ttttgcttct ttcactaatt ttgcgaatgc ttgttgttgg
    18241 aattcagcag ctaaggcttt cgtacgttgt tcttgctctg ctttgctcat ttttggattt
    18301 tcagtcattg cttttaccat accgtcttga acataagctt ttgcttcact ttccatcgta
    18361 ctttgctgtt tcttcactaa ttcagctaac ttggctgctt ggtccgtact taattctacc
    18421 catgtctctg ggattttgaa tgtattcact cggctgtcat attcgtgatt gttatcagca
    18481 atattgaacc agaatttata catgtcgttt ttgtattccc aataagtagt tttcgtcact
    18541 ttttcagcat cgccgtctgt cttttctact ttatttgttt cgttatccgt accagttgct
    18601 tttggttttt cttgtttttc atttgttcgg taaagataca ctttttcttt tccattccct
    18661 aaagctttat acaaaagcat atctgctcct tgggaatcag cactggaaac aattttttct
    18721 gtttttgttt ccgttacttt ttccattcca aagtgattgg acaaattagc gacgatcaaa
    18781 cttagtgaag cgacgaagat tagtccgaaa atcaaagata aaaaggtttg ccatgttttt
    18841 ttagcgaaca cgttcgttaa agcaaaagca agcaagctga caatcaaaac tccaataatc
    18901 atgcattatc ccccgctttc attagaacag gttctttttt cttcaataaa aaggcaataa
    18961 taaagccaag aatcccaaag atgatcgcta cgataaacgc ggcatggtaa cctgacagtg
    19021 tggcattgat tgcctgatct ttataagcta atggcgtatt atccaataca gatttgcttg
    19081 ggatatttgc ttttgtcaca ttcgtcaaca cactgatcaa aatagctgta ccaatcgagc
    19141 ttgcgatttg acggaatgta ttatttaccg ctgtcccatg actgatcaag ttatttggca
    19201 atgcattcat accagaagtc gttaccggca tcatgaccat ggagatccca aacatacgga
    19261 tcgcataaag gatcacgata tataaaactg gagtcgtttt tgtcaagaaa gcaaatggtg
    19321 cagttgccgc tgtcaaaatg aacatccctg tgatggctaa acgtttcgcg ccgtatttat
    19381 cgaaaatcgc acccgtcaca ggcatcatag cccccatgat caatgcaccc ggcaacaaca
    19441 tcaagccaga atggaatgct gattctccac gaatattttg aatatacaat ggtacgacca
    19501 tttctgcccc taccatcgcc atatttgtta caccagctaa aacagctgca atcgtgaatg
    19561 tagatgattt gaatacacga agttccaaga atggatgttc caaatgtaat tgacgccatg
    19621 agaacaaggc gatgaaaatc acaccaacaa ctaagaaacc aattactttc aagcttcccc
    19681 agccgtcatc tcctacacta gaaaatccgt aaagtaaact accgaatcca atcgttgata
    19741 aaatagcgga taaaatatca atgctaggat ttgacaatgg aataacactt ttcattagga
    19801 agaatgctaa aaccaagaca agaacaacga ttggcagtac cataccaaac aagtcacgcc
    19861 aatggtagtt atcaatgata taaccagata atgtagggcc taaagcagga gcaagtccaa
    19921 taacgatccc tgacatcccc attgctgatc ctcttttttc tggcgggaaa atagatagca
    19981 tgatattttg caataatggc atcgatactc ccacaccgca agcttggatc aaacgaccga
    20041 ttagtaatgt actaaaatta ggtgctgtaa agcaagtaat cgttccgatc aaaaagatcg
    20101 tcatggcaga aagatataaa tttcttgaac tgaatttatt gatcagccat gctgttattg
    20161 ggatcatgat cccgttgact agcaagaaac cagtcgttaa ccattgcaca tcagacgctg
    20221 aaatatcgaa agctttcatc aatgtaggaa aagctgtcgt caataaggtc tgattcaaaa
    20281 cggtacaaaa tgtaccaatt aataagacaa caactaaaag tgtccgatta tatggttttc
    20341 cgtaaatatc tacgggttgg ttgttactca tatttctcct tctttctgaa ttttttctga
    20401 aactactaga atactttagt cctaaattcg ctatttgtca acctacttga cacataagtt
    20461 aatacggata taattaaggg aagcaagagg acaaaaggag tgacaaaaat ggttggggct
    20521 tcccttaaac gtttgttgga aaatgatcaa ttggttgttg gcatcagtga attaagtgat
    20581 atcgtaggtg tgtctccacg tcaattaagg tattgggaac aaaagggatt cattcgttcg
    20641 atcgaagctg atgcgaattg tcctagaaaa tatcgtttac ctacagtcat aaaagtagaa
    20701 ctgatcaaaa aatatttaga tgacggattt actttgtcaa aagctgcaga aaaggcagaa
    20761 atccgccaaa agaaaatgca ccatgtccgt aaagtttttt caaaagcaat caaagatatc
    20821 gaattgatcg acgaacgcta tacgatttta caaatcggta acttcaaaga agagaatgct
    20881 aagatgtaca tcattcatga caacgagaca gacgaattaa cttacaagct ccttcctgtc
    20941 gatgaaaaag ctgactacga acagttgtta aaagaactct aaacgccact aatctcctaa
    21001 gtaccaagct ttttaataag tagatgctac ataaatactt gaaaaaaggc ctgtttgaac
    21061 ataagaatat ccgaacggtg atctgcgttt ctttcatata gaaaggaatt ctccatcact
    21121 gttcggatat ttttttattt ttttcggtta ctttcttcta atacatctgt tagccaattt
    21181 gcatattctg tttcccgatt gatcgcatgc gctaaaatca ggtagtgtcc gtaattttca
    21241 tgtttttctt tttcagtagg aaagatcgtt ttttttcgct ctaatagatg aagtcgtttt
    21301 tcttcatgaa ggtcacgctg ctgctgaata atttctacta atgccggatc attcacgtct
    21361 ttgacgaaat acaatttcag aacaaattcg tctcgattaa ccggtagttc attggtgggt
    21421 gtatgaatcc actctgccaa ttgttccttc ccttcttctg ttaattcata aactttcttt
    21481 tccaattttt cacctgtgat ctctacttga tgctgaatga ttccttgctc ttccattttt
    21541 gcaagttcag gataaatctg actatgtttt gcttgccaaa attctcctat ttcatttttg
    21601 aacgattgat tcaattcata tcctgtcatc ttcttcttac ttaataaccc taacaaaata
    21661 tatcgaagtg tattttttct tgccatcagt tttccctcct tgacaaatct ttaaatccat
    21721 tctatcataa atgagtaatc gaaaacatgt agtttattac atgttttaat ttataaggag
    21781 atgcttaaac atgaaagaat ttaaagaatt ggaagatttt attggaactc actttatcta
    21841 tacgtatgac aatggttggg aatatgaatg gtatgccaaa aatgaccata ctgttgatta
    21901 ccgtatccat ggcggaatgg tcaaaggccg ttgggtaaaa gaccaagaag ctgatatcgt
    21961 taaattgacg gacggcgtat tcaaaatcac ttggacagag ccaacaggga cagacgtggc
    22021 attggacttt atgccaaatg aaaagaaact tcacggaatg atctttttcc ctaaatgggt
    22081 tgaagaacat ccagaaatca ctgttacttt ccaaaacgaa catatcgcag aaatggaagc
    22141 agctcgtgaa aaatatgaaa cttatccaaa attacttgtt cctgaatttg ctacgatcac
    22201 ttatatgggt gatgcaggta tagacaatga agatgttatt agcgaagaac catacgatgg
    22261 aatgccagat gatatccgta gcggaaaata cttcgatgaa aattataaac gagtaaaata
    22321 aggttgtgaa agagaggttg tgaaatcagc gttctgacct gagtattaga gaaagaaacg
    22381 gaaaaatagt tcctcatgtt ttgccgtttt ttgagctaat accgagggtc agctgattga
    22441 acaccgttta tcaagaggtt gtgaaatcag cgttatgctt tgagtaataa gaacgctagt
    22501 tagaaaatag cttttcatat tttctaggct agtgggctta ttaccgagaa gcagccgttt
    22561 gaacaccgtt tatcaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
    22621 atggaaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
    22681 tgaacaccgt ttatcaaaga ttgtaacaac tgcatattca cacagttaaa ttagtgactt
    22741 caaaatgaaa taatgctccc agcaaaaaat taggctggga gcattatttc gttattctgt
    22801 tcatcaaaaa tcagcgtttt gattccattt catcacaagt tcctcctcat ttactgcttc
    22861 atctttttgc tgtgtttgaa ttgtaaaacc ttgtgaaaga tagaaatgaa tagctgattg
    22921 atttttttga tagactgtca aagtcagtgt tttattggtt tcttttattt ttttcattag
    22981 ttgcgtaccg attctttgtt gccggtattc ccttttcaca aagattcctg cgataaactg
    23041 atcaatcacc ccagcaaaac caataatttc ttgatctatt tctgctaagt aaatcactgc
    23101 atctggtaaa gctttcctaa cagattctac ttgattctcc caataagttg atggaatgaa
    23161 ttcatgagaa tccaagttag catgcagcca aatcgataga acagattcca gttctttggc
    23221 agacaatttt gttgttgtgc ggatcatttt ttctctcctt acttattcat tgattttaaa
    23281 ataaaaacca tttttttgaa gctcttttac aagttttcgc ccctcaaaaa agtatatctt
    23341 ctcttgtttt acttttctaa taccaaaaga aacagcaact ttaggatcat cagctgaaac
    23401 gattcgataa gttccaccag gcaattgatc cagcttgact ttcccatgat ggtcgctttg
    23461 tactgaaaac ggcacaccat ttctagtaag tgtttttttc ttatgtttca aaatgaatga
    23521 actaccattt accggtttcc ctgacgaatc actaataata aatgaaaaat caagcacttt
    23581 tttacttaat ctatactgat agattagtcg tccgataaac actaacagta tgactacagc
    23641 tattatcgtt cctgcaagaa taaaccattg ccgcatggtt ctttcctgat ttccttttcc
    23701 ttcttctttt tttaccgatt cgttataagg aatccgatgt cctgtcacta gcaaacgatg
    23761 cgtgttgatc atatacggcg tacatgtaag caaggtaact aagtcttctc cttctgaaat
    23821 cgttagaaca gacgtgtcat ctggcagtac cacttgtata tttttaactt gataagccaa
    23881 tttctccccc aaaacagtca aaataaacgt gtctccgttt tctaaacgat ctaattcggt
    23941 aaataaccgt cgattaggta aaccgctgtg agcagagatc actgaatgcg tcgaatttcc
    24001 accaagcggg aaagaggttc cttgcaagac gcctgctcca ttttcaagga tcctaccatt
    24061 gagccgatca taaagtgaaa tatttaattg gatcttaggt atattgatac ttccgatcag
    24121 ccattcctct aattggctgg atgttgtact ttcatttctg ttcttttcat tgaaaggatc
    24181 agtaccagga ttgaatcctt ggtcagttaa tcgttggttt ttctcctcca ttttctttcg
    24241 ctgcacttca atttcagctg cggtccgttt ttgtacttgt tcgatacgtt tttgatcaat
    24301 aaaactattt aaagaatcca cataaaatgg atataaagcg atcagtaacc ctacgacgat
    24361 acatattaat aaaaacaaac gaaacaaaag tcgacgagac tgtttttgct tactctgctt
    24421 cacatgtgtc ctcccttgca agtttttttg ttctttcttt tattatatgg gttcaggaaa
    24481 aaaatagaaa atgaaagccg atgaggttgt gaaaaagctg tcctgcatca agtaataagt
    24541 acagcccaaa aaaatagcta ctcatatttt ttgttgggtt gggcttatta ccgcagatgc
    24601 aagcttttga acaccgttta aggaagaggt tgtgaaaact gcgttatgct ttgagtaata
    24661 agagcgctag tcagaaaata gcttctcata ttttctaggc tagtgagctt attaccgaga
    24721 agcagctgat tgaacaccgt ttaccgagag gtcatgaaaa agctactttg tttcgagtat
    24781 taagaaaaat tctgtttcaa aacaaggaga tgcaacaaaa cttatgtcgc atcctctctc
    24841 cttagaactt tcacttatgt ttttcttgta aaattcataa atattttcat gaattttcta
    24901 atttcttgcc tacctctcgc ataggatata tgatgaattt atctaaagtt tgcaaaggag
    24961 ttcgacaatt gaaaaaatat ggcccatttt tagcaatttt tttcattgct ttggcatttc
    25021 tcatgcctca tttattcaca cataaactaa ttttgggtgc tgatgcccca ttccattaca
    25081 atcggttcta tgatgccgcg caacaaatta aatatgggga tttccattat tttccttccc
    25141 tttatggatt ccagcaaagt ggcaggatcg tgaatgccgt ttacggccca tttttcgctt
    25201 atttacaagg attgatcgtg ttgcttgcag gtagctggtt tcattatcag attctttcaa
    25261 atttcattct ttatcttatt tcaggatttt ctatgctgat tttactgaga tatgtcaatg
    25321 ttcgaaattg ggtaagtgta ccagtagccg ttttattcat gagtacgtat tctattcaat
    25381 actggtctat caaccaagga ttcactagct gggggacttg tttttatcct ttatgtatga
    25441 tccctattgc tgatttcgtc cttcataaaa agttccctgt tatcaaagtc gctgtctcag
    25501 tgggacttat gacacagatc catttactgt cttcgatcat gttagctttg atgtatatcc
    25561 ctttttatct ttattacttt tttaaccaga ctgaaaaagg aaaagcactg cttcaactga
    25621 ttaagtcggt cttgctttat tttgttctga cagcaaatat ttgggcagga ttagctattg
    25681 tttacagtgg gaataagatt cttcctccct ttgttaacag agaaatgagt caaaaggcga
    25741 tagatctgga tggcagttat tggctccatt accctaaggc ctttcctata ttgatattat
    25801 caggtttttt gctttttatt ttctttcaac aaaagaacac cttattccaa aaaatcgtgt
    25861 tgtacacaag tcttgttttc ttttttcttt ctactagctt gattccatgg acgacattga
    25921 tcgaaaaaaa tgtgcctttt attagtttga tccagtttcc atttcgattt ttcgtgccat
    25981 ttacgctatt gcttctactt taccttgccc tttcactgaa ccagtggtct gaacaaaagt
    26041 ggttccgtct tttaagtata tttggcattc ttattttttc agcacagacg atccagaact
    26101 tataccagca tctggaaaag tgggaaaatg aaacatttgt cagtcgacat acttatctat
    26161 tcgatacgcc ggaagaagca aggaaaacat tcttcagcaa agatatgtct accagcttgt
    26221 tcgttttcca aaaaaccaca cctgactatc tgccaatcta taaggagaca aaagacaata
    26281 aatacgaccg gtataacgaa gaaatactag aaaacgaaac aacttttata aaaacacatc
    26341 caggcggtct tttgacaatc aagtggaaaa acactgggga caaaactgtt catatccctg
    26401 ttatcgtcta cgatcggact gtgctacagc aaaatggaaa aacattgact gattatgaag
    26461 taacagatat cgggacccca atcgtgaagc agcaaaaagg aatcaacgag ctcacgcttc
    26521 attatcaaac gccaatctat ttctatttca ttctttctct tactttgatt ggctggttta
    26581 ccttgctatg tttatttatt tatcatagat acaagctttt acgtgcttag gcaaaaggga
    26641 taaatacatc cgatcaaaaa actctccaaa cggtataatc gtttggagag ttttatttta
    26701 atcagttttt ttatgttata tgttatattt tttattcgtt cacatctaat tcgatttcca
    26761 ccccgtagtg atcactgatg attggactat cgatcccatc aaaaatccgt tgatattttt
    26821 taacctgcat tccttcaggg acgaaaataa aatctatacg caatttttct gtattttgtt
    26881 cccaaccatc tattttcttt tccacagtag ctgcttttcc tttttcattc gcgacaacat
    26941 acgaatcttg aagaagaagg caactttctc ttacagtata ataaccttga gagtctactg
    27001 gattattgaa atcacctagg aaaaaaagtg gtacgcgagt ttccaaaaag tagttttcca
    27061 agtttttcca ctcaaaataa aagccacttt ttttatctgt ccaccaagaa aagtggcagc
    27121 tcgagacaaa aatgtcctga tcatctatct ttgttttccc aatcaagatc ttgcgtgtct
    27181 gataatcttc tttcttttga aattgggaga cggtaaggac ctgactttcc aatgtttttt
    27241 tcgtaagcag tgcatttcct tcttcatatt tatcataacc gatgtggctc atttcccaac
    27301 tccaaaaata ctcttttccg tgttccttta aaagctgaac taaacggtag gcaaaattat
    27361 ctttacggat aggtacttga ttctttaccg gacagaactt cattagcttc gcaggttcta
    27421 cttcttcaga ttccagtaat tggttgattt cttgtaaagc aatcacttca taatcttcta
    27481 acaggatctt atctgctaat tcttgcaatt ttttctctgg ttctggctca agccagctat
    27541 gcgtgttgag tgtcatgaat ttcattggtt ttctccttgt cttcatttcg aaacaaaagg
    27601 gttgtgacaa aatttttgtc acaacctctc cagcaaatag tgttctcctg ctaactcctc
    27661 agtaataagc tcaatggacc aggagctatt ttttgtttgg ctgtttttat cacttggtgc
    27721 agggcagctt tttcacgacc tctccactaa acagtattca aactgctgct tctcggtaat
    27781 aagcccaacc aaacgaaaaa taggaggagc tatttttgtt tggctgttct tatgacttga
    27841 tgcaggacag ctttttcaca acctctcctt acattttaat ggagccgatc actttaccag
    27901 ctgtcactgt acctaattgc ttgatcacta cttcttctac tttatcgttt gtaaatacga
    27961 tcatgatcgt tggatctttt tcttcgtttt ggatcacatc aagatccatc tcagctaatt
    28021 tcgttcctgt tcctacttct tggccttctt tgacagcaat ctcaaaagct ggctgattca
    28081 tttggactgt atcgattccc atatggatca aaacttcgat accatctttc gtttccagcc
    28141 caattgcatg tttgctaggg aaaatacttg tcacttttcc agcgatcggc gcaacaactt
    28201 ctcttgatgt tggaataaca gcaaagccgt cacccatcat tttttgtgag aataccggat
    28261 cttttacttc agataaagga atcacttctc cagaagctgc ggaaactagt tcttgttcta
    28321 tacctaagta ttgcttacta cctgcttgtc catttcctgt agaaaccatt tctggctctg
    28381 gaatctctgc tcctgattgc agcagatctt cgatatctga tttcaagaca tctgcttttg
    28441 gtccataaac tgcttggact ccattgtctt tgacgatcaa tcccatcgcc cctgctcgtt
    28501 tccaggcttc ttcagtccct actttttctc gatcatttac acttacgcgt aaccgagtca
    28561 tacaagcatc gacatctttg atattttctt ttcctcccag caaatgaatg atctggacca
    28621 cttgctgatc tgctgttcct gttccgctgt tagatacaac ggtttcttca ctgtcattgt
    28681 cgtaatttcc gttacgtccc ggtgtagcaa agttgaattt tttgatcaag aaatttgcta
    28741 agaaatacgt aacaacacca aaagcgatca cacacaacac gaagttgata agatctccac
    28801 ctagacccgc tttgatagct aacggtgtcc gagtcagcaa ttcgatattc ccaaatgaat
    28861 ggacccgcaa tggcaagata tctgccatcg caaatgcagc cccttggatc actgaataaa
    28921 tgacatataa tggcacagca gcaaacataa acatgaactc caatggttct gttacacctg
    28981 ttagaaagac agccaacgct gctgaaaaat acattgattt atatcttgct ttcttatcag
    29041 gatcgacatt acgatacatc gcaaaagcca ttcccatcaa gatacctgaa gaaccaatca
    29101 tttgtcctac tttgaaacga gccggcgtcc agttatgcaa cacaaactca tattgcgaca
    29161 tatcccctgc acctttaaga ttcactaaat cagtggccca agccaaccat aacggatctt
    29221 gcccaaatac ttgtgtcccc gcctgtgcgc ctgataaaat ctcatacgat ccgccaagct
    29281 gtgtatagtt gataggaatc gtcagcatat gatgcaatcc aaatggcaat agtaaacgtt
    29341 ctaatgttcc aaataaaaac ggtgctagaa tcggtgcgct ttcttgtgat tctgcaatcc
    29401 ataaaccaaa attattgatt ccagcctgta cgtttggcca caccacagca agaatcaatg
    29461 ccacgattgt tgaccataag ataacaacaa acggaacaaa gcgctttcca ttgaaaaatg
    29521 acaaagcatc cggcaatttt ctataattat agtacttatt ataagccatt gccccgacaa
    29581 atccagcgat gatccctacg aatactccca tattcaaagc tggtgcttcc aatacacttg
    29641 taaaaaatcc tttaaccatg atcttcgtac cgaacagagt gtgggtaaat gcatcttcat
    29701 tcgcaagcat gtcacttgtg acaccaaaga tagccccagt gatccgattg attaaaataa
    29761 atgagatccc agctgcaaat gctccgcctg ctctttcttt tgcccaactt cctcctattg
    29821 ctaaagcaaa taaaatatga agattaccaa taattgccca accaatattt tcaattactc
    29881 cgcccgttgt gacaagcggc gtccaatcag gattgatcaa gggaattgat ttccctatac
    29941 tgatcatcaa cccagctgcc ggcataactg ctaccacaac cattaaagcc tttccaaatt
    30001 tttgccaaaa ctcaaaacta aatatctttt tcattccgtt tagctccttt acgcaatcgg
    30061 tttcgttaaa cgtattatag cgtgcgtttt cttttttgta aatgctttat tttttatttt
    30121 tctgtctata ccattctata aaacctataa tacgtgtgtt cccttctata attttctcct
    30181 aaaaatttat ttttttaagc ttttttctat gaaatatttt cttttgtcta ttgacttgtg
    30241 caatcggttg cgtttattat gaacgtataa aacagctcat taggaggaga aaaatgaaac
    30301 agatcaaacg actatttgct attgatccat ggaaaatcag cacgacacaa ttagataaaa
    30361 aaaatcttcg actgcaagaa tctttaacaa gtattggaaa cggttatatg gggatgcgcg
    30421 ggaactttga agaaacttac tcaggggacc accatcaagg tacttatttg gcgggtgtct
    30481 ggtatcccga taagacacgt gtcggctggt ggaaaaatgg ttatccagaa tactttggaa
    30541 aagtgatcaa cgccttgaac tttatcgcga tagatatttc gatcaacgat cagctgatcg
    30601 acttggcttc tttggaacca gaagactttt actgggaatt agatatgaaa aatggtgtat
    30661 tatctcgtac attcacaatc actacttcta ctaataaagt acgcatttcc ttcgaacgtt
    30721 ttctgagcat tgtcaaaaaa gaatcagctt atatctattt aactatagaa atgcttgaag
    30781 gtagcggaac agtcaaactc gtatcaaaat tggatggaaa tgttcaaaac gaagacagca
    30841 actatgatga acatttttgg aatgagattg atcgtggaac tatagaagaa atcggctatt
    30901 tgacgactaa aactattcca aacaactttg ggattgaaca atttactgtt actgcagcaa
    30961 tgcgccattt cgttaatgga aaatcagtca tccctgacta tcacgaagat actttagcat
    31021 tacatggttg cttgtctgca gaattatctc aaggtgagac atggtcagtg gaaaaagaaa
    31081 ttatcgttct tactagtaga gatattccag aagcgcagca agcagaaaaa gctgtctcag
    31141 aattaacgaa ccagacaaac aattatatcc aagcaaaaga agagcaaaca gcggcttggg
    31201 cagaacgatg gaagcttgcc gatgtggtca tcgaaggaga cgaagaagca caacaaggta
    31261 ttcgattcaa tttgttccaa ctattctcta cttactacgg cgaagatgaa cgattgaata
    31321 tcggccccaa aggattcaca ggagaaaaat acggcggagc cacttactgg gatacagaag
    31381 cgtatgctgt ccctctttat cttgctttag ccaaacctga agtaactaag aatctgctga
    31441 aatatcggca taatcaactg ccgcaagcaa tccacaacgc tcagcaacaa ggattaaaag
    31501 gcgcgcttta tcctatggtc accttcactg gtgtcgaatg ccataacgag tgggaaatca
    31561 cattcgagga gattcaccga aatggcgcga ttgcctatgc aatctacaat tatacgaatt
    31621 acaccggcga tacggaatat ttgaaaaatg aaggactgga agttttagca gaaatcgcac
    31681 gcttctgggc agaccgtgtc catttttcaa aacgagcaaa taaatacatg atccacggtg
    31741 tgaccggccc aaacgaatat gagaacaata tcaataacaa ttggtataca aatacgatcg
    31801 cagcttgggt cttgcgttac acgcgagaaa attatttaac ttatcaaaaa gaagctgcta
    31861 tcactatcag cgaagaagaa ctagccaaat ggaaagatat cgcagagaac atgtacttcc
    31921 cagttgacga agaattagga atctttgtcc agcatgacac attcttagat aaagatctca
    31981 tgcctgtatc cgatattccc acaagcgatc ttcctctgaa tcagcattgg tcttgggaca
    32041 aaatccttag atcttgcttc atcaagcagg cagatgtact acaggggatt tatttcttca
    32101 atgatacttt tacaaaagaa gaaaagcaaa aaaactttga tttctatgaa ccaatgactg
    32161 tccatgagtc ttccctttcg ccaagtatcc attcgatttt agcagcagaa ttaggaatgg
    32221 aaagcaaagc tgtagaaatg taccagcgaa cagctcgctt ggatttggat aattacaata
    32281 acgacacaga agacggcttg cacatcactt ccatgactgg tagctggttg tcgattgtcc
    32341 aaggatttgc tcaaatgaaa actgcccatg atcagttgag attcgcacca tttctgccaa
    32401 aaacttggaa agcttattct ttccatatca attatcgcgg acgtttattg ttcatctcag
    32461 tcacagatga acaagttact ttcgagttat tagaaggttc tcctctagaa atttacgtct
    32521 atgaacagtc ttattcttta gcggatcgtc tagaaataac gctaagaaag gaggaagcaa
    32581 atgtttaaag gggtattgtt tgatttagac ggtgtcatta ccgatactgc tgaattccat
    32641 tatcgtgctt ggcgaaagct tggtcaggaa atcggcatta cgatcgacca cacattcaac
    32701 gaacagctaa aaggcgtcag ccgagaagac tcactctctt tgcttttagc ttatggcgga
    32761 aaagaacact ctttttcaaa ggaagaattt gcagaattag cgaaaagaaa aaacgattat
    32821 tatttagaga tgatccagac gatcgaacca aaagatgtct tccccggggt cgtgccttta
    32881 ctggattctt taaaagaaga aaaaatcaag attgctcttg cttctgcaag taaaaacggg
    32941 ccattcctac ttgaaaaaat gggtcttaca ccttactttg atgctattgc cgacccggca
    33001 gaagcaacaa acggaaaacc tgcgccagat atcttcctcc ttgcagcaaa agctgtcgga
    33061 ctaaaagcag aagaatgtat cgggatcgaa gacgcgcaag ccggtatcca agccatcctc
    33121 tcaagtggcg ctcaaccaat tggcgtggga cgtgctgaag accttggaga ggagatcccg
    33181 cttgtccctg atacgacttt tcttacgatc gattacttga aagaaaagtg gcatgaccat
    33241 ggataatcca gagatctccg tcgtaccagt tccagagact gaaataaaga aaatcacatt
    33301 gaagaacgac tacttagaag tcgttcttct caattacggt gcccgcctgc accaaatctt
    33361 cgcaccagac aaagaaggaa aatcagaaaa tgttttattg tcttacgatc gtttcgaaga
    33421 tgttctaaca gacaaaagct tttttggagc aactgtcgga cctgtagccg gaaggatccg
    33481 ggatgcttct tggggtgagc atagattgga gaaaaactgc ggatcacacc atatccacgg
    33541 tggcacgaaa ggctggtctt tccaattttg ggaagtagaa gttttcaaaa ctccatcatc
    33601 aataggtgtg gtcttttact taaaagatga attttctacc tatccaggac caatcactgc
    33661 tacgatcact taccgtttaa caaaaaacga attagagatg acaacctctg ctagtagcct
    33721 tgttgaaacc atctgcaatc cgaccaacca tgcctacttc aacctttcag gaaatggaac
    33781 aagagacatc tatgaacatc agttaacggt ctttttagat ggtgtgcttg aattagatca
    33841 agaaaaactg cctactggaa attggacaaa aaaagaaaaa ctgccaatcg actttagaaa
    33901 atccccaaca ctgcaagaga tccttgcatg ttatccagat ggactagatg atgtatttct
    33961 tttgcatcat cctaggcttt ccaaaacttc cttacaatta ttcgagaagc attctggtcg
    34021 ccaaatgact atagcaactt ctaataaaag tatggtatta ttttctacga ctggattcga
    34081 agctgatttc tctgtcaatg gaaaacagat gcattcaaac tacggattag caatcgaacc
    34141 gcaagaaatc cctgatatcg ttcatttccc caaatttgga tcgatcaacc tccatcctgg
    34201 tcaagaacgg atcagtcaga cgatttatcg gttctctgca caataacaag agaaaggtgt
    34261 ttttatcatg gctattaccg taaaagatgt ggcgaaaaaa gccggtgttg ccacctcgac
    34321 cgtctctcgt gtcatcaacg atcatcctag tatttccgag acaacaaaga agaaagtccg
    34381 aaaaattatg gatgaactag gttatgttcc taacatgact gcccgcaatc taggaaaacg
    34441 catttccagt gccatcggcg taatcttacc ccctcttgat tcaaaagagc ggatcggtaa
    34501 cccattttat cttgagatca tggaagcaat caacgaagaa gcgcggaatt atgatatgac
    34561 tacagcaatc gctactgcta aaaattttga attgctgtta gagaacgtcc agcgtatgca
    34621 tttacaaaaa caagtagatg gttttattct agtgtattca gatagtcaag atactgtcat
    34681 tgattattta taccaaaacc acatcccttt cactttgatc ggacagcctt atcatcatga
    34741 gaacgaaatc gtttatgtag ataatgataa ccagcttcta ggtaaacaag caacagaatt
    34801 tttgatccag aatggacata agaatatcct gtttgtgaca aacacgactc atgaaagttt
    34861 gtatttcgaa cgatatttcg gttatcaaaa agcaatgatg atggctggtc ttcctgcgtt
    34921 atccagtgta gtactagagc atccggagga ttatctgtcc tttgagaaaa cgttgaaaga
    34981 aaacgaagcc acagcattgg tggtcattga cgatatcttc gcccttcgca cgatgcagtt
    35041 ggcgcaaatg tatggctatg tcattccaga gacactctcc gtcattagct tcaacaactc
    35101 gatcttctca acattaacac acccttacct tacaagtatc gatatcgata tctccgaatt
    35161 aggacgtgtc gctatgcaaa agctgcgcga attgatccat gaagaattga gcagtggcgt
    35221 acgtttggtc atccctcatc gcttgatcaa aagagagaca gtcgttcctt tagaaaaccc
    35281 atactaaata gctgactcac taaatacgct gaccatttat cctatggtca gctttttatg
    35341 taaaagaaga tactacttct aacacattgt ttatctgtaa aaaagagcgt gggacaaaag
    35401 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcggaagca gaagcaactc
    35461 cttcggaaat aagctgaaat tcacaaaaat ttaaaaagca attttcttga gtttcttctt
    35521 atttcttgga gttaaacgct tctgtcccag cctctttttt ccttccttca attttttaca
    35581 cgtcgacgat tcaataaaaa accgcctaat attgtaaaga caggtgcaag aatcgagaaa
    35641 aaggcgaatg gcaagtaatg caacgcgcta actttcatcg ttcccataat gaatgtgccg
    35701 ctgactcccc acggtacgag agaattgacg gtcgcacctg aatccgctag tgttcgtgtc
    35761 aaataggttt ttgataagcc aacgtcatca aaagaacgct tgaatgtttc tcctggaaga
    35821 atgatggaca gatactgttc tccaacgatc agattgattc cgatacagct caaggcagta
    35881 aacccgacta aacgagaagg tcggtccatc ttttctttta attcttgaac gatggtatca
    35941 acgatcagat atttgatcag taacccacct aatgccaatg caagtaaaat caaactagca
    36001 gaacctaaca tactcatgat cccgcctcga gaaagcagtt catctagctt tggatcaggt
    36061 gtatttgcga cataaccatt catcaagatg tctgctgctt ttccgaccgt caaacttttc
    36121 tcatggataa aagaaagaac gagagcagct gtcgatcccg ctagtaatgt agggatagcc
    36181 ggaatttttt tgattgcccc cccaaataaa ataactagtg gaatcaatgt ccaaggagag
    36241 atccaaaagc tcgctttcat gttttggatc atttcattga tactagctag atcggctgaa
    36301 tgactgttat gtcctaatat cgtataaaaa atcaacgaaa ggacgaatgc tgggaaatcc
    36361 gtataacgca taccagcgat atgttcgaat agattaactc ctccaatacc cgctgccaag
    36421 ttggtcgtat ctgataaagg cgagcagtta ttccctaaaa aggcaccgga aacgactgcg
    36481 cctgtagtca ttgcatcatt gaatccaagt aaatgaccga tccccaaaaa agcaattcca
    36541 atcgtcgaaa tcgttgtaaa tgaactgccg acagtcactc cgacaattgc acaaacaaga
    36601 aatgctgtcg gtaaaaagaa acgcacagaa acaagtttaa atccataaac cataatcgta
    36661 gggatggttc cagataaaat ccatgaagca actaagacac caatcaaaag aaaaatcagg
    36721 attggaatga tccctggagt gatttctttg atgatcccgt catggatctc atcccatgtg
    36781 aactttttaa atctgccata aaacaacaaa cacatgaaag ctgcaaggat cgggatatgt
    36841 ggcgagagct ggaatccgat gatcagtact cctaggagtg ccaacaacac gatcaataca
    36901 gcgatacttt cttttaaaga aatattttta ttcatcgtcg atctcctatt tcaaatgaaa
    36961 aggccctgcc atgaaaaaac tattcacttg gcaggacctc ctactaaatc agcgacaaaa
    37021 cgtcggctga aagacttatt tttttatttt tcttctaaac ttttttctac ctcaatcccc
    37081 caagaatctt tcttgaagtg attgatgatc aatggaataa cgaacatgac cactgtgata
    37141 gctgctacta ataatgcatc actcaatgtc gctgtaccta atgtagcaaa tacgacaacg
    37201 atgatagaga agatcagcat gcagctgact acccaagcta atccgtttcc gtttttacca
    37261 attcggtaag gacgttcgaa ttctggatgt ttcttacgca ttttaagcaa tgaaacagca
    37321 atcaaaatgt acacgataca ataaataaca gttgtagcat ttgtaagtgt caagaataca
    37381 gcacttacgt catccattac accataaagc aaagcaaata atgaaataac gattgattgt
    37441 gttagaacga catttctaga tacgccgtat ttgttttctt tatggaatcc gaattttggt
    37501 ggaaggaatc cttcacgagc tacttggatg attgtttttg atggtccagt aacccaagct
    37561 gataattgta aaagcacacc aataaatacc atgaagctga agatatttcc gatcacttct
    37621 ggtaagccta ggatttgaca gtcaatcaag ataggctgcg tgatatttgc taattccatt
    37681 tttccatctg gtacgacatt tgctacaagc atcgcattga tgacattcaa taaaactaat
    37741 ccgatcaaag cgataaatac gccttttgta taattttttg ttgcgtcttt caaacgaggc
    37801 atgtaaacag aactcatttc gatcccaaca aaaataaatg tgataccagc taagtatttc
    37861 aatgaatcaa tatgttccaa gtcagggaaa gcttttgacc atgaaaagtc acctagatag
    37921 ccgtttgaga ctagtccgac tttgaaggct gccaaaacac ctaaaacgaa catgatgact
    37981 actgggatat atacccctag ccatacaccg atgttcccgc cgacttttgc catatcgaat
    38041 ttcaagttca agatcgtgat gatccagtag ataactaaaa tacaacctaa aacgaaccag
    38101 tgattattgc caagttctac attaccaaat gtgtttccta acaatggtcc taaagtagaa
    38161 gcgaccatta ccatacctgg gaacatttgc acccataata gccatgcaac gacaaatccc
    38221 catttgctgc ccagtgctgt ttttacccat aactgaggac cgccttcttg aggaagcatc
    38281 gtggaaagct caccggaaac cattgatatc ggaccggcaa aaaacaaaac tgcaaaaatt
    38341 gaataaaaaa tcaatgtcca accgactgcg gctaacgtag gaatactccg aaccgttgca
    38401 cacagtgcca ttgtcagacc gataaaggtc ccaagaccca ttttacttac ttcagattta
    38461 ctcaccgttg acactctcct tgattttttg gataaaataa cggtgtcttt gaagtagttt
    38521 cagcaataaa cgaaacaatt cagcgaatat ttgaggggat tctttgagtt tattgcttga
    38581 agggtttctt caaagacaac ctcaaaacaa agggatcgaa gagcttaggt ctccccttgc
    38641 tcttcagatc caaacatgcg tcagaaacag ttagtattca agctgttttc taacatgatt
    38701 accttgctta ttttgcttcg cttgccaata attggtctgc gtagattttt tccaattttt
    38761 cttgaagagc tgctttgatt ttttcagcat attcttcaaa gtgttcttct ttgttcatgt
    38821 atggtgtcat tacgctggca cgcaatacag ttacttttcc ggcacggttc cattcttcat
    38881 ctgagaatcc tagttggttc acaaattgta atgggctgtt gccatagtct gggatagcaa
    38941 agtcagtatg tgaagttaag aactcattac cgtaaatgct tcctttcacg tatgaagaat
    39001 aatcatatac gtcatggttc aatttattca ttgcaactaa gtcatcgttg cctttttctt
    39061 tgaatacata gtctaccata ttgaaatctg gataagttaa tggatgaact tcgatttctt
    39121 tgtctcctac tttaaatgac aagtcattca agaagttgta gaaacgatgt gcaccttcga
    39181 ttgatgcacc cattaattta ccatatcctg tgacattcaa aggtaagaca tggtgtgctg
    39241 cccaaacgct ggctgctgtt gcccctgctt ttgaaccttc caagatataa gccccaagta
    39301 atgctgggat atctgcgcct ttttcaaata catatgtcgc aaagtaagag ataacgtctc
    39361 tcatgcggat atctttgatg acgataccac cggcagaata tggaacatag cccattttat
    39421 gtgggtcaat cgttacagat tctgcttctt cgattgcttt atatgcactg tgtacttctt
    39481 ctaagatata atctttgttt tctgtaaaga cattgtattt gtaatgaaca tcttttaaat
    39541 cttcaaatgg aatgaagttg ttgtcttcgt ctaagaaaat cgcacggccg tatccgccat
    39601 aagcagcatc tacgtgtaag tagaagtaaa taccgtcttt ttctaatacg cgacgcaatg
    39661 caacgatttt atcgataccg tcgattgctc cttcttctgt tgatcctaca acaccgacta
    39721 cacctaggat tggtgttttt tcagctgcta gaccacgaac gattttttca agttcgttga
    39781 tgtccatgcg atagttgtgg tcaactggca ctggaatcac ttggtctaaa ccgataccga
    39841 tgatgtcggc agcttttagc catgaatagt gtttagtttg tggaaccaac cattttccta
    39901 atttttctaa atgttttccg ctacgtgctg agtgagcttt gatttcgtcg attttttctg
    39961 ggacgctgtc taacagattc atgatttctt ctgttgacaa gttcattaat tcccaatcgc
    40021 tttttccagc aactagttca ggtgtcactt ctttcattgc aagcggcaat gatttgatgt
    40081 tgcgggcata ccaaagtcct tctaagtttg ctaaagaacc atcagcaacg atgtggcccc
    40141 agccatcttt atagctcatt aattttgcaa attccattcc tacttcttct tccatttggc
    40201 ttgttgcagg agaagattca taggcaacgt tattaccatt ccatagcata gcaaaattgt
    40261 acgctagtaa agatggcatc aatgtttcag agttcatatg accccagtaa cgtccggcat
    40321 tatgccaagg aacggaatgg gtacgcatcc gcgctgaaat ttctgataga acatcctttg
    40381 ttttattcac agtgtgttca aaactagcac tgcttttttc ttctggcgta ataataggca
    40441 tgtcttgagg catgtagttt tgacgccagc ctaaatgttc atccaccaat tcattcaaca
    40501 aagctttata gatttggccg ttctcagctt tgtccccaat gaatagggca tttaggttta
    40561 gatctttcga caatgattca ctcatagtga aaccctccta aaaaaatatt taaattttgt
    40621 cgagccctac attacacctg ttcttctatt ctgtaaacta agttttggcc tgatttttaa
    40681 tcatatttta atatgtatca attatccgaa ttgttcacac ttttgaaata attaaaaaaa
    40741 acgagggaat ttacaaatgt aaactccctc gcaaagattg tattaacgac aaccagcgtt
    40801 ctattttagg atgggtttca aaattggaat gttgtaatag tatttccctt tttcaaggta
    40861 aaaacttact aaattctaat caattacttt ggccaaaaag taatttttct taccttttcg
    40921 aataaccaca aacttaccat cgaattcatc ggatggattt atgacaaaat ttaaatcggt
    40981 aacgcggtca ccgttaatac ttatagctcc gtttgaaaca tcttcacgtg cttgacgttt
    41041 agatggttca atttttgtgg aaacaagcag ttccacgata ttttcaggtg tgcttgaaat
    41101 ttcaacgttc ggcattttac cgaatccttg cgcgatttct tccgcattta gttctttaat
    41161 atttccagag aacaatgctt gcgttatttt ttgcgcttct ttcaagtctt cttcactatg
    41221 cacaaatctt gtaacttctt ctgccaaacg gcgttgtgct tcacgtttct caggttctgt
    41281 ctctactttt ttcgctaagt cttcgatttc ttcttgagac aagaaagtaa agaatttcaa
    41341 gtatttcact acatcgcgat catcttgatt caaccagaat tggtagaact caaatggtga
    41401 agttttcttc ggatcaagcc aaacggcacc gcctgcagtt tttccgaatt tcgttccgtc
    41461 agccttcagc atcaatggga tcgttaaacc gaacgcttct gcttctggtc cttctaattt
    41521 tcggattagg tctaatccag ctgtgatatt tccccattgg tctgctccac cgatttgcaa
    41581 ttgcacatcg tatgttttat gcagatgcaa aaagtcgata gattgcagga tttggtaagt
    41641 aaactctgta aatgagattc ctacttccaa acggctggca acgatatctt ttgctaacat
    41701 cgtgttgatg ttgaagtttt taccgtagtc tctcaaaaat tcaagtaaag agatttttga
    41761 caaccagtcg tagttgttca caaatgtgat atttgcatct ttaccaaaca attttctcat
    41821 ttgattggaa agtgcgtcca cgttatgttg cacttgttcc atcgtttgca acacacgttc
    41881 tgttttgcgg ccgcttgggt cgccgatcgt tcctgttccg ccgccaatca gaatatatgg
    41941 atgatggcct gccaattgga atcttttcat catcataaat ggaatcaaat gtccgatatg
    42001 catcgaatca ccagttggat caacgccgca ataaagtgaa atgctctttt cttcaacgag
    42061 ctcgcgaagt ctttcttcgt ttgtttgctg attaatggcg tcgcgccaag ttaattcatc
    42121 aataatattc attttactga cctccgtgta gtttttttat gaaagcagga acctgctagc
    42181 atgtgtaatt aattatttct tcaggatagg ataggaaata aaaaaagtcc cttggcatat
    42241 aagccaaggg acgaaatctc gcggtaccac ccaatttgta tgtctagata tccaacatac
    42301 ctctcgaaca tttaacgctg tcgcgtggca atcactgcca aagactcctg aaatgtaatt
    42361 cgctttaaag catgtactgg tttgcagcga ccaccagctt tctgaaacat tggctttaac
    42421 aactacttcg tttcgatctt cgtcttgtta ttattaatat gtgtctatca tagagcgcaa
    42481 ctttttcttt gtcaacagaa aaaggatatt ttttttaaat tcctcatttt ttcttttttg
    42541 aatccgctct aattccgaac attttatttt caattattgt taaaagaaat aactttttct
    42601 gtattttttc tgcaatttat cgagaagtca ctttactttg cctcttattc tttcttcgtt
    42661 acaataagga atgggacaag taaaaaaatg aaaaagcaag ggacgaggta tatggaaaaa
    42721 aagcaaaaaa ttattttagg agccacttct gctttaacta tcgttatttt aattctaagt
    42781 ttgttttttg tcatccgatc atctacaaaa aaagaaccaa tcattcctga aaaaaaaata
    42841 acagaaaaag caaaagaacc gacagatgat aagcaacaac tagttactca agcaaaaaat
    42901 ctggctcaaa gctacgatta tgaccaagcg attgcgttat tggaaaaaga tagtaagaac
    42961 ggatctactg aaacacaaca gcttcttcaa acactaaaaa aggagaaaga acaactgatc
    43021 gactggtctg atcctactca gatctctcat gtctttttcc acagcttgat cgtggacccg
    43081 caaaaagcct tccactctca acaggcacaa ggatacaaag attatatggt gactgttgaa
    43141 gaattcaacc gttcgatcga acaactttat caaaatgatt ttgttttagt taatttgaat
    43201 gatttgatcc aaaaagacga acaaggaaat ctttccttta acgggcttgc gctacctgaa
    43261 ggaaaaaaac cattggttct ttcacaagat gatgtcagct attatgaata tatggataat
    43321 tccggttttc ctagccgatt ggtcgtatca aataacaatg aaatcaaaaa tgtctataaa
    43381 gagaaagata aagaagaaat cggtgacttt gacatggttc ctctgatcga tgcctttgtc
    43441 aagaaacatc ctgatttttc ttatcgaggc gcaaaaggta ccttggccct gacaggttac
    43501 aacggagttt taggttatcg aacatcaaaa tctcaatatg gagacaatga aaaaacaaaa
    43561 aaagagatta aagaagctaa aaaagtggcg gaacagttga agaaagacgg ctggagcttt
    43621 gcttcccata catggggtca cttgaatatg actcaagctt cactagaaga tgtaaaaaaa
    43681 gacaatgaat tgtggcagca agaagttgca cctatcctag gaaaaacaaa tattctgatt
    43741 tatccatttg gtgcagacat cagcgactgg cagccttatt cagcagaaaa tcaaaaattt
    43801 gcttacttga agagtcaagg tttcgatatt ttctgtaatg tcgatgcttc tacaccagct
    43861 tggggacaat taggtacgga tttctatcga aatgctcgga tcaatatcga tggcattcgt
    43921 tttcaatctg atttagacgg aaaaaatcct attcttgatc cattcatcaa tgtccatgat
    43981 gtctatgaca aagaagcacg cgaatctgct tgattttacg tcatttatga accaaaaaag
    44041 ccgaactgac attttatcgt cagtttcggc ttttttatgc tttatttctt cttcggtgcg
    44101 attcccttga tcaggacttc tgtccattct gctgtatatg gaagcagttt tgcgtatatc
    44161 tccggcttag aaattccttc taccattgct tgaaaataga ggatcaagaa ctcatccgaa
    44221 tatttcaaat ccacttttcc ttctttccgc cctcgatgga aaagatcaag catgatactg
    44281 aaactttctt gcgtatacgc atccatcgcg tcagaaaatt cttttttttc tttttttgta
    44341 tagtatgtca tcaaatcgat ataaaattgt ttgttcactc gattgagata acggattttg
    44401 ttttcactca tggcaatcag tgtttcttca aatggaagat tttccgcaat caacgctttc
    44461 gcttcttgcc ctaaatcatt cataaatgca aaaaatactt cataaatcag cccttccttg
    44521 ctgccaaaat atttaaaaat cgtcgcttta cttacctgag cgttctcagc taccttatcc
    44581 attgtcactc cagcggttcc tatgtctgtg ttcatcaagt caaaagctgc ttgtaaaatc
    44641 tctttctttt tctcttgtgc tctcttttca aaaccgttca tttgtagagc ctcccgtaat
    44701 tttaaacttt tataatatat atagttcaaa tttattctga ggtttattat aactatctat
    44761 tgagaaagta tcaagctagc aattccttgt ttatgaattc attgacagaa atttataaa
//
LOCUS       DADVXB010000006        44347 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.006, whole genome shotgun sequence.
ACCESSION   DADVXB010000006 DADVXB010000000
VERSION     DADVXB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.006"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(185..1750)
                     /gene="guaA"
                     /locus_tag="KB902_000223"
     CDS             complement(185..1750)
                     /gene="guaA"
                     /locus_tag="KB902_000223"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6807081.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLDGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(1809..2732)
                     /locus_tag="KB902_000224"
     CDS             complement(1809..2732)
                     /locus_tag="KB902_000224"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBB6807082.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADSLLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            2928..3533
                     /locus_tag="KB902_000225"
     CDS             2928..3533
                     /locus_tag="KB902_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6807083.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGT
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYHRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            3846..4571
                     /locus_tag="KB902_000226"
                     /pseudo
     CDS             3846..4571
                     /locus_tag="KB902_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            4703..6043
                     /locus_tag="KB902_000227"
     CDS             4703..6043
                     /locus_tag="KB902_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6807084.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            6105..6404
                     /locus_tag="KB902_000228"
                     /pseudo
     CDS             6105..6404
                     /locus_tag="KB902_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
     gene            6545..7846
                     /locus_tag="KB902_000229"
     CDS             6545..7846
                     /locus_tag="KB902_000229"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBB6807085.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILASLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            7892..8554
                     /gene="deoC"
                     /locus_tag="KB902_000230"
     CDS             7892..8554
                     /gene="deoC"
                     /locus_tag="KB902_000230"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBB6807086.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            8575..8973
                     /locus_tag="KB902_000231"
     CDS             8575..8973
                     /locus_tag="KB902_000231"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBB6807087.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRELLPYAFTEKDL"
     gene            9039..10121
                     /locus_tag="KB902_000232"
     CDS             9039..10121
                     /locus_tag="KB902_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6807088.1"
                     /translation="MRKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            10333..11895
                     /locus_tag="KB902_000233"
     CDS             10333..11895
                     /locus_tag="KB902_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807089.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            11888..13021
                     /locus_tag="KB902_000234"
     CDS             11888..13021
                     /locus_tag="KB902_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807090.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            13021..13977
                     /locus_tag="KB902_000235"
     CDS             13021..13977
                     /locus_tag="KB902_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807091.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            14076..15242
                     /gene="deoB"
                     /locus_tag="KB902_000236"
     CDS             14076..15242
                     /gene="deoB"
                     /locus_tag="KB902_000236"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBB6807092.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            15266..16084
                     /locus_tag="KB902_000237"
     CDS             15266..16084
                     /locus_tag="KB902_000237"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6807093.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            16101..16808
                     /gene="deoD"
                     /locus_tag="KB902_000238"
     CDS             16101..16808
                     /gene="deoD"
                     /locus_tag="KB902_000238"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6807094.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(17106..17792)
                     /gene="gpmA"
                     /locus_tag="KB902_000239"
     CDS             complement(17106..17792)
                     /gene="gpmA"
                     /locus_tag="KB902_000239"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6807095.1"
                     /translation="MPKLVFSRHGLSEWNTLNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(17964..18545)
                     /locus_tag="KB902_000240"
     CDS             complement(17964..18545)
                     /locus_tag="KB902_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6807096.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(18678..19361)
                     /gene="rpiA"
                     /locus_tag="KB902_000241"
     CDS             complement(18678..19361)
                     /gene="rpiA"
                     /locus_tag="KB902_000241"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBB6807097.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKGFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            19680..20093
                     /gene="rpsL"
                     /locus_tag="KB902_000242"
     CDS             19680..20093
                     /gene="rpsL"
                     /locus_tag="KB902_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBB6807098.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            20177..20647
                     /gene="rpsG"
                     /locus_tag="KB902_000243"
     CDS             20177..20647
                     /gene="rpsG"
                     /locus_tag="KB902_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBB6807099.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            20741..22828
                     /gene="fusA"
                     /locus_tag="KB902_000244"
     CDS             20741..22828
                     /gene="fusA"
                     /locus_tag="KB902_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6807100.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            23000..24187
                     /gene="tuf"
                     /locus_tag="KB902_000245"
     CDS             23000..24187
                     /gene="tuf"
                     /locus_tag="KB902_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6807101.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            24593..24901
                     /gene="rpsJ"
                     /locus_tag="KB902_000246"
     CDS             24593..24901
                     /gene="rpsJ"
                     /locus_tag="KB902_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBB6807102.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            24932..25561
                     /gene="rplC"
                     /locus_tag="KB902_000247"
     CDS             24932..25561
                     /gene="rplC"
                     /locus_tag="KB902_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBB6807103.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            25589..26212
                     /gene="rplD"
                     /locus_tag="KB902_000248"
     CDS             25589..26212
                     /gene="rplD"
                     /locus_tag="KB902_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBB6807104.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            26212..26502
                     /gene="rplW"
                     /locus_tag="KB902_000249"
     CDS             26212..26502
                     /gene="rplW"
                     /locus_tag="KB902_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBB6807105.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            26541..27374
                     /gene="rplB"
                     /locus_tag="KB902_000250"
     CDS             26541..27374
                     /gene="rplB"
                     /locus_tag="KB902_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBB6807106.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            27417..27695
                     /gene="rpsS"
                     /locus_tag="KB902_000251"
     CDS             27417..27695
                     /gene="rpsS"
                     /locus_tag="KB902_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBB6807107.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            27718..28065
                     /gene="rplV"
                     /locus_tag="KB902_000252"
     CDS             27718..28065
                     /gene="rplV"
                     /locus_tag="KB902_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBB6807108.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            28079..28735
                     /gene="rpsC"
                     /locus_tag="KB902_000253"
     CDS             28079..28735
                     /gene="rpsC"
                     /locus_tag="KB902_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBB6807109.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            28738..29172
                     /gene="rplP"
                     /locus_tag="KB902_000254"
     CDS             28738..29172
                     /gene="rplP"
                     /locus_tag="KB902_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBB6807110.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            29162..29350
                     /gene="rpmC"
                     /locus_tag="KB902_000255"
     CDS             29162..29350
                     /gene="rpmC"
                     /locus_tag="KB902_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBB6807111.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            29375..29641
                     /gene="rpsQ"
                     /locus_tag="KB902_000256"
     CDS             29375..29641
                     /gene="rpsQ"
                     /locus_tag="KB902_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBB6807112.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            29699..30067
                     /gene="rplN"
                     /locus_tag="KB902_000257"
     CDS             29699..30067
                     /gene="rplN"
                     /locus_tag="KB902_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBB6807113.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            30104..30412
                     /gene="rplX"
                     /locus_tag="KB902_000258"
     CDS             30104..30412
                     /gene="rplX"
                     /locus_tag="KB902_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBB6807114.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            30440..30979
                     /gene="rplE"
                     /locus_tag="KB902_000259"
     CDS             30440..30979
                     /gene="rplE"
                     /locus_tag="KB902_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBB6807115.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            30998..31183
                     /locus_tag="KB902_000260"
     CDS             30998..31183
                     /locus_tag="KB902_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBB6807116.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            31219..31617
                     /gene="rpsH"
                     /locus_tag="KB902_000261"
     CDS             31219..31617
                     /gene="rpsH"
                     /locus_tag="KB902_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBB6807117.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            31649..32185
                     /gene="rplF"
                     /locus_tag="KB902_000262"
     CDS             31649..32185
                     /gene="rplF"
                     /locus_tag="KB902_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBB6807118.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            32346..32702
                     /gene="rplR"
                     /locus_tag="KB902_000263"
     CDS             32346..32702
                     /gene="rplR"
                     /locus_tag="KB902_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBB6807119.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAKAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            32723..33223
                     /gene="rpsE"
                     /locus_tag="KB902_000264"
     CDS             32723..33223
                     /gene="rpsE"
                     /locus_tag="KB902_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBB6807120.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            33238..33417
                     /gene="rpmD"
                     /locus_tag="KB902_000265"
     CDS             33238..33417
                     /gene="rpmD"
                     /locus_tag="KB902_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBB6807121.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            33461..33901
                     /gene="rplO"
                     /locus_tag="KB902_000266"
     CDS             33461..33901
                     /gene="rplO"
                     /locus_tag="KB902_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBB6807122.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            33901..35196
                     /gene="secY"
                     /locus_tag="KB902_000267"
     CDS             33901..35196
                     /gene="secY"
                     /locus_tag="KB902_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBB6807123.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIRLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            35258..35905
                     /locus_tag="KB902_000268"
     CDS             35258..35905
                     /locus_tag="KB902_000268"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBB6807124.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            36096..36314
                     /gene="infA"
                     /locus_tag="KB902_000269"
     CDS             36096..36314
                     /gene="infA"
                     /locus_tag="KB902_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBB6807125.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            36347..36463
                     /gene="rpmJ"
                     /locus_tag="KB902_000270"
     CDS             36347..36463
                     /gene="rpmJ"
                     /locus_tag="KB902_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBB6807126.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            36481..36846
                     /gene="rpsM"
                     /locus_tag="KB902_000271"
     CDS             36481..36846
                     /gene="rpsM"
                     /locus_tag="KB902_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBB6807127.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILANAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            36874..37263
                     /gene="rpsK"
                     /locus_tag="KB902_000272"
     CDS             36874..37263
                     /gene="rpsK"
                     /locus_tag="KB902_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBB6807128.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            37343..38281
                     /locus_tag="KB902_000273"
     CDS             37343..38281
                     /locus_tag="KB902_000273"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBB6807129.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            38309..38689
                     /gene="rplQ"
                     /locus_tag="KB902_000274"
     CDS             38309..38689
                     /gene="rplQ"
                     /locus_tag="KB902_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBB6807130.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            38961..39800
                     /locus_tag="KB902_000275"
     CDS             38961..39800
                     /locus_tag="KB902_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6807131.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            39776..40645
                     /locus_tag="KB902_000276"
     CDS             39776..40645
                     /locus_tag="KB902_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6807132.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            40635..41432
                     /locus_tag="KB902_000277"
     CDS             40635..41432
                     /locus_tag="KB902_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6807133.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            41635..42381
                     /gene="truA"
                     /locus_tag="KB902_000278"
     CDS             41635..42381
                     /gene="truA"
                     /locus_tag="KB902_000278"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6807134.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            43046..43283
                     /locus_tag="KB902_000279"
                     /pseudo
     CDS             43046..43283
                     /locus_tag="KB902_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(43427..44203)
                     /locus_tag="KB902_000280"
     CDS             complement(43427..44203)
                     /locus_tag="KB902_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6807135.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
BASE COUNT        14197 a         8212 c         9543 g        12395 t
ORIGIN      
        1 aagctaattc aataggaaaa taaaggtagt gaataaaagc aaagcccttg ttagtagtta
       61 atctaacaag ggctttggta gggaaaatgg taggaaacca tcttattttt tacgaaaatc
      121 aggaacttta gtaattgaat aatgttgatt tataggtatt cctcatccat attatgttgg
      181 ctctttattc ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt
      241 tgacgtgggc tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga
      301 tacgggcaaa gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt
      361 agtcgtaagt acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga
      421 aatattgcca gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat
      481 cagattcgcg tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa
      541 gaccaggacc agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc
      601 ctaattcacg gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca
      661 tatcttctgg cagtccacct acattatggt gagatttgat cgtttgtgct gtttctgtac
      721 cagattcgat aacgtcagta tacaacgttc cttgtgctaa gaaagagacg ccttcttcac
      781 catcaagttt tgttgcttca tcatcaaaaa catatacgaa ttcattccca atgattttac
      841 gtttttgttc tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcatcga
      901 ctttgatgat gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc
      961 ctttgcgtag cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt
     1021 gtaaaagaac cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt
     1081 tgtcaccaac ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc
     1141 agttaccttc acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt
     1201 cggaatgacg tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga
     1261 tagaagcaat cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag
     1321 ttaccaagtc accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga
     1381 cagcttgatc gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct
     1441 ctacggaacc gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag
     1501 gaatacctaa attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt
     1561 ttggtccgcc agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa
     1621 tgcggtggct caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt
     1681 ggttatactg actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa
     1741 cgtttgtcaa atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt
     1801 ttaaaatgct aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg
     1861 agaattatat cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc
     1921 acatttttcc atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa
     1981 cgataataat aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc
     2041 aaataccatt tttcgatcag caaggaatca gcatcgacat agacagaaaa atcaaaaaag
     2101 tcgctgacgt agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc
     2161 aagatatcag gttgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt
     2221 gagtaaacag gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc
     2281 agcatctcca tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt
     2341 aatatacgat ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg
     2401 aaggtacgag acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca
     2461 cttccggcga tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct
     2521 ttactcaaga acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt
     2581 acatagatat ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct
     2641 agttcatctt gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt
     2701 gccacacggt agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg
     2761 gaactatttt aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt
     2821 ttgtataatc tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca
     2881 taaaaggata gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt
     2941 actattctga acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag
     3001 gcagaacctt tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg
     3061 gttcacgtgt cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct
     3121 tagatgtggg atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt
     3181 ttgttgaaat ggtcgacatt aatgaacgag cggtaagtct agcgcaagga accgcaaagc
     3241 gtaaccaaat cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag
     3301 aaacctatgc agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg
     3361 aaattttgac aggcgcatat catcggttga agaagggcgg tacactgaca attgtgatcc
     3421 agaagaaaca aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggcaatgcag
     3481 aaatcgtcac aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg
     3541 aaaaatagtg gagcgacgaa agagtggaac tgggcgtaca tattacatat atggtacgca
     3601 tcagttcttt ttttattgat gactttttta atcaaggaac tatcttttct taaaaaagaa
     3661 gtagcagaat cagaatcatg tttttttacg ataaaataaa taagatacag aacttgtata
     3721 gaaggctgcc aagtcggtag ataaaggaga tttttatcaa aaaacatact ttcctttttt
     3781 ctctattctt ttcttggggg ttttggtaca ctgataggga atttagatag aagggagcca
     3841 ataggatgaa gctgaccatc agagatatcg cagaaatggc aggcgtatca gtaacaactg
     3901 tctcacagat tttgaataac aaaggaagca gatttagtga taagacaagg aaaaaagtgt
     3961 tgtcgatcgt gaatgaacat cattataagc ccgattattt cgcttcaaat gtgatcaatc
     4021 gacattcaaa gaccatcgga atgatcgtcc ctgatgtcac tgatttcttc ttctccaaac
     4081 tgatcgaagg tgtagagagc tatttgaatc ctttgggcta tgtgatcatg ttatgcaatt
     4141 ctcgtcatag ccaagaaaat gagatcaagt atttacaaga gctttcccac cgctcagtgg
     4201 acggaatctt gctggccaca ccaaatattt tacctgagaa atacgcatta gacagcggat
     4261 tttatcaaaa aatgccaatc attttaatcg atcgcggatt gaatcgtcgg gataacggac
     4321 ggcttatcgt aaaggaatat gagggcgcct atcaagctgt ttcgctgttt attgaaaatg
     4381 gccatacgaa gatcggcatg ctgaaggaaa ccactggata ctatcaatta gaagaacgtt
     4441 tcaacggata tcgtcatgcg ctgaaagatc atggcctgcc ttttaatggg aaatttgttg
     4501 aacatggaga gttgactgtc caaggtggat atactgcatc aaaaaaatta ctcaaacata
     4561 aagatatcac ggatctataa tatctagtgt tggtgacgcc ttctgttgcc aatacttttt
     4621 cttttttcta ataaacgcaa acagacacct tgaaatcctt tagaataaag tcgacgaaaa
     4681 ccattcaaag gagtgtttca agatgtccta ttcagagttt accaaagagt tactagatat
     4741 tctagaccta aatcttacct ttcatgaaga tgcctttcgc aaagagcgca ttaatgacga
     4801 aacatgtttt gtttttgatg gcacattgac ctatcaacca gaggaatgct tccattgcca
     4861 ctatcaaaat aagcaaacga tcattaaatg gggctggaaa aaagtatcca tcttattgaa
     4921 tgatgtcagt aactacaaga ccattgtgcg gattaacaaa cagcgcttca aatgtaaaca
     4981 ctgtggaaag acttttttag cagaagattc agttagcgat cgtcgctgct ccattgcccg
     5041 cagagtcaaa caagccattc ttgagctatt aagtgagcct atttctatgt ctttgattgc
     5101 acgtatgaag cacatttctc cgaccactgt cattcgaata cttcgcagcc ttcggcctaa
     5161 aaccgtttct ttgaaccagc cgttaccaga agtggtgtgt ttcgatgaat tcaaatcggt
     5221 gaaaaacgtc tcgggagcca tgagctttgt catgatggac ggcaagaccc atcaactgat
     5281 tgatattgtg gaaaatcggc aactcaatcc tttacgcgac tatttcttgc gctaccctag
     5341 aaaagtccgt gaacaagtac gtctagtggt ttcagatttc tatacaccct atcgcacatt
     5401 ggtgaaagag tgttttccga atgcccgaat cgtcgccgat cgctttcata ttagccaaca
     5461 catcggtcgg gcctttacca accaccgaat tcaagtaatg aagaccttta aaaaagggga
     5521 tcgtcggtcg aagcacttaa agaaatactg gagactactt caaaagaatg cgtgggaatt
     5581 gaatggtcag catcgctact ggcgtccgtc atttcgagat catctgacag aagcggagat
     5641 agtcgatcgg ctattatatt atgatgactc cttaaagcga ggctacgaag tctaccaggt
     5701 ttttctttcc gctatcagaa gacaagatgt tcctgaattc gtcgcgctcc taaaagaaga
     5761 ctacaaggag ttgccagagc actatcaacc agtgttcacg accttcaaga aatatcgaac
     5821 agaaatcaaa cgagcgttgc gagttcccta ttccaacggc cctatagaat gtttgaacaa
     5881 ccatatcaaa gtactaaaac gaattgccta tggctttaga aactttcaaa actaccgaga
     5941 acgaatcttt ttatatcgag gaaaatattt caagaaaact aagaacacta cccaactgac
     6001 taaagccaga acaacaacac ggctagacaa gatagctgtc tagccgtgtg agtatctcga
     6061 ttattctatt gaatttcttc accaacactc attgacgaag agccgatatc acggctattt
     6121 tttgcgggaa tgatgccatg gcgatcggat gctatcaggc gatcgatgaa ttgggcaaaa
     6181 aaatcccaga agatatctca gtcataggat tcgatggatt aaagctgtca gaatacatga
     6241 ttccgcaatt gacgacagtg cagcagccaa gttttgatat tggattttat gctgcacgtt
     6301 tcctgatcga tacgatcgaa tttcctcaaa gaaaagttcc gaacaaagtg ttcgaaacaa
     6361 aattaattat tcgtgagagc gtaaaagtat tgacaaaggg ctaactcggc ggtatatcgc
     6421 ttatgtaagc atttacaaag gcgagttagt gcttttttta tttttagtaa accagtttac
     6481 taaagtggtt tacctttcct aaaaataatg tataataccg aatgaagaca aggaggatca
     6541 ggcaatgcga atggtggatc tgattgaaaa aaagagggat ggaaacgagc tgtcgaaaga
     6601 ggaaatcgag tacatcgtca cgaactatac gaatggaaag attccagatt atcaagtcag
     6661 tgcattattg atggcaattt tttatcaaga catgacaaat gaagaaatca cgaacttaac
     6721 attggcgatt gctaattctg gtgatgtcat cgatttgagt tctcttgaag gaataaaggt
     6781 agataagcat tcgacaggtg gcgttggtga cacgaccaca ttgattttag cctccctagt
     6841 agctagtgtc ggagtgacag tggctaaaat gtctggacgc ggtctaggtt acacaggtgg
     6901 tacactagac aagctagaag caattcccgg atttcagatc gagctttcgg atgaagaatt
     6961 tgtacgcatt gttaatgaaa gtaaagtagc ggtaattggt caatcaggaa acttggcacc
     7021 ggcggacaaa aaattgtatg ccttgcgtga cgtcacagcg accgttgatt ctcttccgct
     7081 gattgccagt tcgattatga gtaaaaaaat cgcggcagga gcagatgcaa tcgttttgga
     7141 tgtgaccact ggagacggtg ctttcatgaa gaacatcgaa gatgcaagac gtctggcaaa
     7201 gaccatgacg agcattggga aactggctaa ccgagaaaca gtggcggtta tctcagatat
     7261 gtcagaacct cttggcgaag ctatcggaaa tagtctagaa gttgtcgagg caatcgaaac
     7321 attacaagga aatggtccag aagatctagt agaaatgtgc tacgccttag gaagccaaat
     7381 ggttgttctt gctggcaaag ctaagacaac cgatgaagca agaacgttgc ttcaagaagc
     7441 tctggaatca ggtaaagcgt tagcaaaatt caaagaaatg atccaaaatc aagggggaga
     7501 cccagcgatc gtggaacatc cagaacgaat tttgactgca cgctacacaa tggagcttcc
     7561 tgctaaacaa agcggagttg tgtcaaaaat cgtggcaaat gaattaggaa ttgctgcaat
     7621 gatgctaggt gctgggcgta aaaccaaaga agaagatatt gatcacgctg ttggattgaa
     7681 actgcataaa aaaattggtg acactgtgac aaaaggtgag tcactattga cgatctatag
     7741 taacgacgaa gaaatcactt ctgtcattga attattatat aaaaatattg aaattggtga
     7801 atcggcaatg aagccaacgt tgattcatga catcatcaca gaataaagga aaaaagcgga
     7861 ctttaccgtt ttaaagaaaa ggggaaaaga aatggaacta aaccgaatga tcgaccatac
     7921 tattttgaaa gcagacgcat ctaaagaagc tgtgatgcaa attatcgaag aagcaaaaaa
     7981 ataccatttt tattctgtct gcatcaatcc agcatgggtt gcgctagcga aagaacaatt
     8041 acaaggtgag ccagtagccg tatgtacagt aatcgggttt cctctaggag caaacacacc
     8101 cgagacaaaa gcatttgaaa caacagatgc catcaataac ggtgcagatg aagtcgatat
     8161 ggtcatcaat atcggtgctt tgaaatcaaa ggatgatcaa caagtccaaa aagatatcga
     8221 agcagttgtt gaagcagcaa aagatcgtgc gcttgtcaaa gttattattg aaacatcgtt
     8281 attagataga gaagaaatca tccgagcttg cgaaatagca aaagctgcag gcgctgattt
     8341 tgtcaaaaca tcaactggtt tctcaacagg cggagcaaag gtagaggatg tccgtttgat
     8401 gcgtgaaact gtaggaccag aaatgggtgt caaagcttcc ggcggtatcc ataacgaaga
     8461 agaagcaatg gcaatgatcg aagctggtgc tacaagaatc ggaacaagcg caggagtagc
     8521 aatcgtatct ggttcaactg gtgaaggcta ttaatttttt caaaggagaa gctcatggca
     8581 gaactcaaac aagaatggat caacacagct attgaagcgt tagataaagc ctatgttcct
     8641 tattcccatt ttccggtagg cgcttgtctc gtaacggaat caggcaagat ttatcaaggc
     8701 atcaacattg agaatgcatc atttggatta acgaattgtg ccgagcgcac agcttttttc
     8761 aaagcagtat ctgaaggaga aaaaacattt acgcatctag tcgtagcggg gcacaccccc
     8821 gatcctatct ctccttgtgg tgcatgtcga caagtaatgg cagaattctg ttcccctgat
     8881 atgccggtta cgctagtagg agataatggt gtgacgaagg caacgaccgt tcgtgaactg
     8941 ctgccttatg catttactga aaaagatcta taactcatgt tcattcagtc agctgactgt
     9001 tgaaaaataa aacaattatt ttaggaggct ttacagaaat gagaaaagca aaattatttg
     9061 gtttaggtgc tgtcgcacta gcagcagggt tatttttagg tgcatgcggc aacaacggtt
     9121 ctactgattc atccggtggc aaaagctcat cagacacaac aactgcagca ttgatcacag
     9181 acacaggtgg tgtagacgac cgttcattca accagtcagc ttgggaagga ctagaaaaat
     9241 gggggaaaga tcaaggactt tcacgaggaa atgatggctt ccaatatttc caatcttcaa
     9301 atgaatcaga ttacatccca aatattgacc aagcattgaa tgctggattc aaaacgattt
     9361 ttggtattgg ttataaacta aaaccagcga tccaagaaca agcaacaaac aatacaggta
     9421 cgaactttgt tattatcgat gatgtcatcg atggattaga taacgttgta tctgcaactt
     9481 tcaaagacaa cgaagcttct tatcttgcag gtgttgcagc agcttatacg actgaaacaa
     9541 acgtagtcgg ctttatcggc ggtgtaaaag gtgaagtaat cgatcgtttt gatgctggat
     9601 tcaaagccgg tgttgatgca ggtgcgaaag aattaggaaa agaaatcaaa gtattgaatc
     9661 aatatgctgg tgacttctct gctccagata aaggacgttc aattgctcaa ggtatgtatg
     9721 cacaaaacgc agatatcatc ttccatgctt caggcggtac aggtaacggt gtattccaag
     9781 aagcaaaatc attgaacgaa tcaggcgaca aaaaagtatg ggttatcggt gttgaccgcg
     9841 accaatcaga cgaaggcgaa tacacattaa acggcgaaaa gaaaaacttc acattgacat
     9901 ctacactgaa agcagttgga acagtagtag aagatttggc acaaaaatca gcggacggta
     9961 aattccctgg cggcgaacac actgtttatg gattgaaaga agacggtgtt ggtctaacag
    10021 aaggacaact ttctgacgaa gcaaaaaaag cagttgatga agcaaaagaa aaaatcattt
    10081 caggtgacgt aaaagttcca gaaactcctg aagaaaacta aaaccatttc tatagccttg
    10141 ttagacacat gtttgacaag gctatggttt gattagaaca agaattgttc atttatccaa
    10201 gctgccttgt gacagtttgg ataagggaac aattccctga agtaatgttt gtttcaaaag
    10261 aagaacgctc actaagcgtg aatcttagtc aatcgttgcc ctagatagaa atcgttagga
    10321 tgtgaaaaaa aggtggttca agaaaatatt gtcatagaaa tgcagaatat taccaaagaa
    10381 tttggaacat tcaaggcaaa tgacaacatc aatttacaag taaaggcagg agaaattcat
    10441 gcgttgcttg gagaaaacgg tgctggcaaa tctacattga tgaacgtgct ttccggatta
    10501 ttagagccga catcagggaa aattttgatg cgtgggaaag aagtaaagat cacaagtccg
    10561 accaaagcca accaattagg gattgggatg gtccatcagc actttatgct tgttgatgcc
    10621 tttactgtaa cagaaaacat cgtgttggga agcgagccta gtcgcgcagg gatgcttgac
    10681 cataaaaaag cacgaaaaga gatccaaaaa gtttctgaac agtatggatt gtcagtcaac
    10741 ccagatgctt acgttcgtga tatttcagtt gggatggaac aacgggtaga aattttaaaa
    10801 acactttacc gaggagcaga tgtactgatt tttgatgagc cgacagctgt attgacccct
    10861 caagaaattg atgaattaat cgtgatcatg aaggaattag tcaaagaagg caagtcgatc
    10921 attttgatta cgcataagtt agatgaaatc aaagcagtag ctgaccgctg tacagttatc
    10981 cgccgtggaa aaggaatcgg tacagtcaac gttaaagacg taacctcaca acaattagcc
    11041 gatatgatgg ttggaagaac ggtttcattc aaaacgatga aaaaagaagc gaagcctcaa
    11101 gaagtcgttt tgtctattga aaatctagtg gtgaaagaaa atcgtggatt agaagccgtg
    11161 aaaaacttga acttagaggt tcgtgctggc gaagtacttg gtatcgctgg aatcgatgga
    11221 aacgggcagt cggagttgat ccaagctttg actggtttgc gaaaggcaga aagcggacat
    11281 atcaagctaa aaggggaaga catcactaat aaaaaacccc gaaaaatcac tgaacatggt
    11341 gtaggacacg tgccagaaga ccgtcataaa tacgggttag tcctagatat gacattatct
    11401 gaaaatatcg cactacaaac ctatcatcaa aaaccttaca gtaaaaacgg catgctgaat
    11461 tattcagtaa tgaatgaaca tgccagagaa ttgatcgaag aatatgatgt tcgaacaacg
    11521 aatgaacttg ttcccgcaaa agctttatca ggcggaaatc agcaaaaagc aattatcgct
    11581 cgtgaagtcg accgagatcc tgatctgttg attgttgcaa atccaactcg tggactggat
    11641 gtaggtgcga tcgaatttat tcataaacgt ctgatcgaac aaagggacaa atacaaagca
    11701 gtgttactga tcagtttcga attagaagaa attttaaatg tttcggatcg tattgctgtt
    11761 atccatgaag gagaaattgt cggtatcgtt gatccgaaag aaacatctga aaatgaatta
    11821 ggtctattga tggcgggcta taccttagaa gaagcacgaa aagagttaga aaagggggct
    11881 ggcgcacatg aatgatcgca gcgaaaaatt ccgtaattta ttagtgcctg tactttcagt
    11941 tgttttagga ttgatcttag gcgcgatatt gatggctgct tttggttttc agcccatcca
    12001 aggttattct tctatgctag atgcagccct tggttcgcaa agagggatag gtgaaacgtt
    12061 aaggcaagca acgccgttga tttttacagc attaggtttt tctgtagcta actcagctgg
    12121 gtttttcaat attgggcttt ctggacaagc actttgcggg tggatcgtca gtgtctgggt
    12181 ggcacttgcg tttccagatc tgccaaaagt tgttttgctt ccgttatgcg tgatcttagg
    12241 tgccttagct ggtgcgatgg cagcggctgt tccaggttta cttcgagcat tttttggaac
    12301 aagtgaagtg atcgtaacaa tcatgatgaa ctatatctta ttatacgtaa gcacatttgc
    12361 tttacatgaa gtgatgcctg aaagctatcg ctcaagtttg gactcttcca atatgatcag
    12421 tcaaaatgcc tcactgcggt taccatggtt aacacaagct tttggcggct ctcgcgtaaa
    12481 ctcaggtttg tttttagcaa tcatcgcgct tattttcgtt tggctgctga tgaagaaaac
    12541 gactttagga tttgaaatcc gttctgttgg attgaatcct tttgcttctg agtatgcagg
    12601 aatgagtagt aaacgtacga tcgttttgtc gatggtcatt tctggcgctt tggcagggct
    12661 tggcggtgtg gttgaaggat taggaacgta tcaaaacttc tttgttcaaa cgacttcgct
    12721 atctattgga tttgacggaa tggctgtctc cttgcttggt tctggatcag caatcggtat
    12781 tcttttatca gcgatcttgt tcagtatttt gaagatcggt ggacttggca tgcagacagg
    12841 agcaggtgtt ccgtttgaga tcgtcaatgt atcgattgct ttgattatct tctttgtcgg
    12901 gatcaacttc ctgattcgtt tcgtcatggc taaagtcttc caagggaaaa aacaagaaga
    12961 gatcgttgcg acaatcgaat cgaaaccaac gaatcaaaac catgaagggg gcgaactata
    13021 atgtcgacta tcgaattaat tgccttgatc cttacttcta cactggttta ttcaacaccg
    13081 ctaattctaa cgtcactagg cggaactttt tctgaacgaa gcgggatcgt aaacgtaggg
    13141 ctagagggaa tcatggtcat gggtgctttt agttccatcg ttttcaactt gacgatgagt
    13201 ccatcacttg gttctatgac accatggatc gctattttag tgggtggcgt cgtaggtatc
    13261 ctattttctc tgattcacgc agtagcaaca gtcagtttgc gtgctgacca tatcatcagc
    13321 gggacagtaa ttaatctgat ggcacctgct ttaggtgttt tcttgatcaa agcatggtat
    13381 ggtaaaggtc aaactgataa catcacgcag aatctggggt atttttcttt cccaggatta
    13441 gcagatattc cggtcattgg accaattttc tttaaaaata cattcttacc tgcttattgt
    13501 gctattttga ttgctgtcct agcttgggtg atcatcttca agacgaaatt cggcttgcgc
    13561 ctccgttcag ttggtgaaaa tcctcaagct gccgacacat taggtatcaa tgtatatgct
    13621 atgcgttatt caggcgtact gatttctggc ttgttaggcg gtatgggcgg tgctgttttt
    13681 gctcagtcga tttccggtaa cttttcagct ggtacgatcg ttggacaagg gttcatctcc
    13741 atggctgcta tgatctttgg taagtggaat cctttagggg caatgggtgc ctcattgttc
    13801 tttggttttg ctcaaagctt gagtatcatt ggcgcacaat taccagttat ttcttcgatt
    13861 ccgccagtat tgctgcaaat tgctccatat ttgctgacaa tcattgtgct ggttgttttc
    13921 ttagggaaag cttctggtcc aaaagcaaac gggaagaact atatcaaatc aaaataatct
    13981 tttagcgaat aaaaagggtg ggttacggga agtgtttttc gtctcgccct ttttgtttta
    14041 aaggcaataa aaataaaaag aaagaaggaa taatcatgtt taaacgcgta catctgatcg
    14101 tcatggattc agtaggaatt ggagaagcac cagatgccga taagttcggt gatgttggtt
    14161 ctgatacatt aggacacatt gcgaaagaag caggattgaa cgttccacat ttagagcagc
    14221 ttggtttagg aacgatccgt cctcttgaag gtgtggaatc agtgaaagat catcaaggct
    14281 atgcgacgaa attagaagaa gtttctgtag ggaaagatac gatgacaggc cactgggaaa
    14341 tcatgggatt gaatatcaaa actccatttc gtgtgtttcc gaacggattc cctgatgatc
    14401 tgatcaaaca aatcgaagaa ttttctggcc gtaaagtcgt atgtaacaaa ccttatagcg
    14461 gaacagctgt tattgacgat tacggtgaac accaaatgaa aacaggcgat ttaattgtat
    14521 atacttctgc cgatcctgtc cttcagatcg cggcacatga agaaatcatt cctttagaag
    14581 aattatatcg gatttgccaa ttcgttcgtg atataacaaa agatgatccg tatatgattg
    14641 gccgaatcat tgcacgtccg tacgtgggtg aaccaggaga cttcacacga acaagcaatc
    14701 gccatgatta tgcgttgaat ccattcggac acacagtcct tgattctttg aaagaagcag
    14761 gaaaggacgt gattgctgtt ggaaagatca acgatatttt caacggacaa ggaatcactg
    14821 aatctgtccg cacgaaaagc aatatggatg gcgttgacca gctactgaaa gttatgaaaa
    14881 acgatttttc aggaatcagc tttaccaatt tagtagattt tgatgcatta tacggtcatc
    14941 gtcgggatgt agtcggctat gcgcatgcga ttgaagaatt tgacttacga attccagaat
    15001 tgcttgaagc gatggaagaa gacgacttgc taatgattac agccgatcac ggaaacgatc
    15061 cgacgtttac tggtaccgat catacgcgag aatatgtacc gttattggtt tacagtaaaa
    15121 aaatgaaaga acaaggggca ttgcctcaag gatattattc agatatttca gcaacgattg
    15181 ctgagaactt tagtgtttct tcgactgaaa atggcgaaag cttcttgaaa ttattaaaat
    15241 aatcttttta aataggagaa agcaaatgac caagttaagc gagatgttac aagaaacgac
    15301 ccagtttatc cttgataaag gagtaaaaga aattgatttt ggtttgattc taggttcagg
    15361 attaggtgaa ttagcagatg aaatcgaaga tgctgtaatg atttcttatg atgagatccc
    15421 gttctttcct gtttcgacag tagttgggca tgcaggaaag ctagtttatg ggtctctggc
    15481 aggcaagaaa gtgttagcca tgcaagggag attccactac tatgaaggtc attccatgca
    15541 aacagtgacc tatccagtac gtgtgatggc cgggctagga gcccattcag tcattgtgac
    15601 taatgcatgt ggtggtgtca acgaatcatt tgtaccagga gatttgatgc tgattaccga
    15661 tcatatcaat tttactggtg aaaatccttt gatcggtccg aatgaagatg caatgggccc
    15721 tagatttcca gatatgagtc aagcttatac gcctgactat caagcaacag caaaagcagc
    15781 agcagaaaaa ctaggtttgg atcttaaaga aggcgtatat atgggctatt ctggaccaac
    15841 ttatgaaacg cctgcggaga tccgaatgtc tcggacaata ggagccgatg cagtagggat
    15901 gtcgactgtt ccagaagtca tcgtagcagc tcacagcgga ttaaaagtgt taggaatctc
    15961 ttgtattacc aacttagcag caggtatgca agcgaatctg agccatgaag aagttgtaga
    16021 aacaactcag agagtcaaac aatcttttaa agcattggtt aaagaaacat tgacattatt
    16081 gtaataggag gaacaataaa atgagtgtgc atattgaagc gaaagaaggc gagatcgccg
    16141 ataagatttt acttccggga gatcctttgc gagctaaata tattgcggag acttttttgg
    16201 aagatccagt ttgttacaat caggtacgcg gtatgttagg ctttaccggc aaatataaag
    16261 gagaacgtat ttctgttcaa ggaacaggaa tgggaatgcc atcagccacc atctatgccc
    16321 atgaattgat ccagtcgtat ggtgtaaaga aattgattcg agtaggtaca tgcggtgcat
    16381 tgtcaaaaga cgtccatgtt cgtgatttag tactagcaca aggtgcagcg accagttctt
    16441 cgatgatcga aaaaaatttc caagcctttc attttcctcc aattagtgat ttcaatctat
    16501 tactgaaagc atatgagata gctaaagaaa agggctatac ggttcatgta ggaaatgttc
    16561 tttcggaaga ttctttctac aaagatgatt tgacagagac attccaatta gctgaacttg
    16621 gcgttttagg agtggaaatg gaagcagcgg ctctttatta cttaggcgcg aaataccatg
    16681 tgcagacatt aagtttgatg accgttagcg accatttgat caccggtgaa gaaacaacag
    16741 ctgcagaacg tcaatctacg ttcaatgaaa tgatcgaagt aggattggaa acagcgatag
    16801 cagaataaga aggaaatgaa aaagctgccc tgcattaagt aataagaaca tccaagcaaa
    16861 aatagctcct catgtttttg acttggctgg acttattatt gcaaatgtaa gcttttgaac
    16921 accgtttacc aagaggttgt gaatctgccg tttaactctg agtcacaagg aacaatttca
    16981 aaaaacagct tttcatgttt gatgaatatt gtgacttgtg accgagaagt tggcaggaga
    17041 acaccgttta tacgaaaaaa gggactgtga caaatcgtgt cacagtccct tttttatagt
    17101 gttttttata ggtagtattt tttagcaact gttaagtcat catttaattc ataaacaagt
    17161 ggttgacctg ttggaatttc aagatccatg atgtcttcgt cagagatacc ttcgatatgt
    17221 ttagctaggg cgcgtaatga gttaccatgt gcagctacta aaacagtttt gttgtctagt
    17281 aatgctggag caatttcatc ttgccagaat ggcaaagcgc gttctaatgt cactttcaag
    17341 ttttctccac caggaatatc gcgtttgtct aacattgcgt aacgacggtc atttgctgca
    17401 gaaccttcgt cagtttcttc cattaatgga ggaagagtat cgtaagaacg acgccagatg
    17461 tgtacttgtt cgtcgccgta tttttcagct gtttcttttt tgttcaaacc ttgtaattta
    17521 ccatagtgac gttcgtttaa gcgccatgat ttgatttgtg gtacccaaag ttgatctgaa
    17581 tattctaaga tcaagttaca tgttttgatt gcacgagtta aaacagaagt gtaagcaaca
    17641 tcaaattcga ttccagcttc tttgattttg cgtccgcctt cttttgcttc ttcgattcct
    17701 tctggtgcta gatttacatc agcccaacca gtaaattggt tcaatgtatt ccattcacta
    17761 agaccgtgac gagaaaaaac taattttggc atgtttagct ctccttttaa gataggttta
    17821 tatttctgaa attttcagtt ctgttttatt gtacaatttt ttggaagaga tttccatcga
    17881 aaaattagat aagattctat gagaaaacaa gtagagaata taaaaaaacg aacagtgccc
    17941 acgcaactgt tcgtttttag gtattagatg cataattgct cgatttcttt ttcaggtaaa
    18001 ttgatatatt tataacatgt tccaactgaa acaccgcatt ttgaagaaat aaattggatc
    18061 gtttcttttt tttcataata gagacgtcgg atttttttga tcgtttttgc atcgattttt
    18121 ggtcttccgc cgatttttcc ttttttacga gcttcatcta atccaactaa tgtacgttct
    18181 ttgatcaatg cgcactccat atttgctagg ttttccatta attggaaata gatttttccc
    18241 atttcgcgcg tatcgattcc ttcatcaaga ctaatcaagt gcagcccgcg atctttgaat
    18301 aattgcgtga gttctgttaa ttgccgcgta gatttgccta atcgatgaag ttggcaaatg
    18361 actagtgcat cgccttgttg catgtcagcg atcactgact ccaaatgaac agcagtagaa
    18421 tcattttgtt ccacttcata tgtctcatgg aaaatttctt gacaaccaaa gtcagataat
    18481 tgatcaacct gagttgttaa atcaacgtca tttatggttg tgcgtgcata accaataatt
    18541 ttcatggtga ttcctttcta gcagtgattt tctaactgga tataacagta aaaatgtagc
    18601 ataaagtacg tcaaaaagat agttttttcg caaattttcc gctgtctttt tttattggat
    18661 gatcaagcag tttttcttta tttacgacgg attgcgtcaa gaatctcaac gcctttttct
    18721 gagccgacaa ctactttaga aaccatgttt aggaaaagcc catgttctac taccccaaca
    18781 agttcatcta aataggtagc taagctttct ggctgttcga tgacttctag atgcagatca
    18841 atgatgtaat gaccaccatc tgtggttagg acttctccgt tttcgtctgt acgcaagaca
    18901 ggttggaatc ctttttcttc aaaaatatga agtagctgtt gggagccata agggatcact
    18961 tcaactggga gtgggaactt cccaagttta tcgactaatt tagaagaatc aacgatccaa
    19021 atcgtttctt ttgagtacgt agcgactatt ttctcgaaaa gcaaagcagc gccgccgcct
    19081 ttgatccctt gaaaatcagc actgatttca tcagcaccgt ctattgtcaa atcgactacg
    19141 gggacttcat caatactctt taacggtatt cctaattttt ccgcttgttc ttttgtcgca
    19201 tttgaagtag taactcctgt gatacgtaaa ccttcttcac gcatacggcg accaatctct
    19261 tctaccatat aataggcggt tgaaccggtc ccgagaccta cgatcatccc gtcctttacg
    19321 aatttcgcgg cttcaatgcc agctaattgt tttaaattca tctttgcgtc cacctttttt
    19381 tagtttgagc atcgtgcttt cctcactatt ttagcgtgat ttacggtaaa aagataccat
    19441 tcttttttat tccaataaag ctttttcaaa aaaaattgca tcccttgttg acatgttttt
    19501 tcattcgtga tattctaaca aaggtgcttt atctacaggt ttctgtgaag aaacgtgctg
    19561 actgtttatc aaagcatatt tgataaggat gcagacattg catttatttt ttatcacaaa
    19621 aaaagaacca cctggatgtg tggaactaga cgcaaatcgt gggaaggagg aaacaaggaa
    19681 tgcctacaat taaccaatta gtacgtaaac ctcgtaaatc aaaggtggaa aaatctaatt
    19741 cacctgcttt gaacaaagga tataacagct ttaagaaaac tcaaactaac gtaaactcac
    19801 ctcaaaaacg tggggtagca actcgtgtgg gtacaatgac acctaaaaaa ccgaactcag
    19861 ctttacgtaa atatgcacgt gttcgtttgt caaacttaat tgaagttact gcttatatcc
    19921 cagggattgg tcataactta caagaacaca gtgttgtatt attacgcggt ggtcgtgtaa
    19981 aagacttacc aggggtacgt taccatatcg ttcgcggtgc tttagatact gctggtgtta
    20041 acgaccgtaa acaaagccgt tctaaatacg gaactaaaaa acctaaagct taattttaat
    20101 tattaaacaa atgaaacttg cttctactat atagaagtaa ttactatgaa caatatttcg
    20161 gaaggaggag ttacggatgc cacgtaaagg tcctgttgca aaacgtgatg ttttaccaga
    20221 tcctatttat aactcaaaat tagtaactcg cttgatcaac cgtgtaatgg ttgacggaaa
    20281 acgcgggatt gcagctaaca ttatctataa tgcctttgac ttgatcaaag aatctacagg
    20341 taacgatcca ttagaagtgt ttgaacaagc aatgaaaaac gttcaacctg ttcttgaagt
    20401 taaagcacgt cgtgttgggg gttcaaacta ccaagtacca gttgaagttc gccctgaacg
    20461 ccgcgttact ctaggtcttc gttgggtagt aaactacgct cgcttgcgcg gtgaacacac
    20521 aatggaagaa cgcttagcaa aagaaattat ggatgctgca aacaacacag gtgcttctgt
    20581 taaaaaacgt gaagacactc ataaaatggc tgatgccaac cgtgcgtttg ctcactatcg
    20641 ctggtaagat tctctctgtt tggtcggctt ttataagtcg acctcagata gtgtccttat
    20701 ttttagcaac tagatagtaa agagaggaga aacaaggaga atgaccagag aattttcttt
    20761 acaaaacact cgtaatatcg gtatcatggc ccacatcgat gctggtaaaa cgactgctac
    20821 tgaacgtatc ttgtactaca ctggtaaaat ccataaaatt ggtgaaactc atgaaggagc
    20881 ttcacaaatg gactggatgg aacaagaaca agaacgtggt attacgatca cttctgctgc
    20941 tactacagca caatggaagg gtcaccgaat caacatcatc gacacaccag gacacgtaga
    21001 cttcacagtt gaagttgaac gttcattgcg tgtacttgat ggtgctgtaa ctgttcttga
    21061 tgcacaatca ggtgttgaac ctcaaactga aacagtttgg cgtcaagcaa caacttatgg
    21121 tgtacctcgt atcgtatttg caaacaaaat ggacaagatc ggtgctgact tcttatattc
    21181 agtatcaact ttacatgatc gtttgcaagc aaacgctcac ccaatccaat taccaattgg
    21241 tgcggaagac gacttcacag gaattatcga ccttgtaaca atgaaggctg aaatgtatac
    21301 aaacgatctt ggaacagaga tcgaagaaac agaaattcct gaagaatacc gcgaattagc
    21361 tgaagaatgg cgcgaaaaat tggttgaagc tgtagctgaa actgatgaag aacttacttt
    21421 gaaatactta gaaggtgaag aaatcactga agctgagtta aaagaaggta tccgccgcgc
    21481 aacagttaac gtagaattct acccagtact atgtggttca gcatttaaga acaaaggggt
    21541 tcaattacta ttggacgctg ttcttgatta cttgccatca ccgttagata tcccagctat
    21601 caaagggatt gaccctaaaa ctgatgaaga agtagaacgt cctgcagacg acagcgctcc
    21661 tttctcagct ttagcattta aagttatgac tgacccattc gtaggtcgtt taactttctt
    21721 ccgtgtgtac tctggtgttt tacaatcagg ttcatacgta caaaacgcaa caaaaggcaa
    21781 acgtgaacgt gttggtcgta tcctacagat gcatgccaac tctcgttcag aaatctctga
    21841 agtttacgct ggagatatcg ctgctgctgt tggtttgaaa gacacaacta ctggggacac
    21901 actatgtgat gaaaagagtc tagttattct tgaatccatg gaattcccag aaccagttat
    21961 ccaagtcgct attgaaccta aatcaaaagc tgaccaagat aaaatgggtg tggctttaca
    22021 aaaactatct gaagaagatc ctactttccg tgctgaaaca aacgtggaaa caggcgaaac
    22081 aatcatcgct ggtatgggtg aacttcactt agatatcatc gttgaccgta tgcgtcgtga
    22141 attcaaagtt gaagctaacg taggtgcgcc tcaagtatct taccgtgaaa ctttccgtgc
    22201 tggcactcaa gccgaaggta agtttgtacg tcagtctggt ggtaaaggtc aatacggtca
    22261 cgtatggatt gaatttacac caaatgaaga aggtgctggt ttcgaatttg aaaatgcgat
    22321 cgtcggtggg gttgttcctc gtgaatacat tccagctgtt gaaactggtt tgaaagatgc
    22381 tatggaaaat ggtgtcttag ctggctatcc attagtagat atcaaagcta aactttacga
    22441 tggttcatac catgatgtcg attcaaatga aactgccttc cgtgttgctg cttctatggc
    22501 attacgtgca gcagctaaga aagctaatcc agtaatcctt gaaccaatca tggctgtaga
    22561 agttgttatc cctgaagatt acttaggtga tgttatgggt cacgtaactg ctcgtcgtgg
    22621 acgtgttgaa ggtatggaag ctcgcgctgg cggccaacaa gttgttcgtg cgatggttcc
    22681 acttgctgaa atgtttggtt atgctacaac tcttcgttct gctactcaag gtcgtggtac
    22741 atttacaatg acatttgacc actacgaaga tgtaccaaaa tcagtacaag aagaaatcat
    22801 taagaaaaac ggcggaaaag ctgaataatt tcttaaaacc ggatagtcct gcaaagagat
    22861 tatccaaaga gactatattt ttaatatagt ttcgtgtaaa ataattatcg atgatatggg
    22921 catgtggtgt accttgtgta catcatatac ctatcagaca aataaaaaat atattgtatt
    22981 tttaggagga cattttaaaa tggcaaaaga aaaatttgac cgttctaaac cacacgttaa
    23041 cattggtact atcggacacg ttgaccatgg taaaactaca ttaacagctg caatcacaac
    23101 tgtactatct aagaaaaacg gcggccaagc tatggcttac gatcaaatcg atggtgctcc
    23161 agaagaacgc gaacgcggaa tcacaatctc aacagctcac gttgagtatg aaacagatac
    23221 acgccactac gctcacgttg actgcccagg acacgcggat tacgttaaaa acatgatcac
    23281 tggtgctgct caaatggacg gagctatctt ggtagtttct gctgctgacg gcccaatgcc
    23341 tcaaactcgt gaacacatcc tattgtctcg tcaagttggt gttccttaca tcgttgtatt
    23401 cttgaacaaa gtagacatgg ttgatgacga agaattacta gaattagttg aaatggaagt
    23461 tcgtgaccta ttaacagaat acgaattccc tggtgacgat gttcctgtag ttgctggatc
    23521 agctttgaaa gctctagaag gcgacgcttc atacgaagaa aaaattcttg aattaatggc
    23581 tgcagttgac gaatacatcc caactccaga acgtgacaac gacaaaccat tcatgatgcc
    23641 agttgaagac gtgttctcaa ttactggacg tggtactgtt gctacaggtc gtgttgaacg
    23701 tggacaagtt cgcgttggtg acgaagttga agttgttggt attgctgaag aaacttcaaa
    23761 aacaacagtt actggtgttg aaatgttccg taaattgtta gactacgctg aagctggaga
    23821 caacattggt gctttactac gtggtgttgc acgtgaagac atccaacgtg gacaagtttt
    23881 agctaaacca ggtacaatca cacctcatac aaaattctct gcagaagtat acgtgttgac
    23941 aaaagaagaa ggtggacgtc atactccatt cttcactaac taccgtccac aattctactt
    24001 ccgtacaact gacgtaacag gtgttgttga attaccagaa ggaactgaaa tggttatgcc
    24061 tggcgacaac gtaacaatgg aagttgaatt aatccaccca atcgctatcg aaaacggtac
    24121 taaattctca atccgtgaag gcggacgtac agttggtgcc ggtgtcgtta cagaaatcaa
    24181 agcttaattc acttaagttt taaagtaaag caacatttat tcggacgtaa tcgctcggaa
    24241 cgaaggtctc aggatctttg ttccgagctt ttttatttat tgcaggatca ggaaaaaaga
    24301 caggagtatt ataatagaag gaacgcgaaa taaaagagtc agtattttct aaatgaaact
    24361 ttatgaaaac aaaatgtttt ttacaagaaa aatccttgct ttgtgagttt atatatatta
    24421 taatgacaaa ggtgcgttta ctttagtgaa ttgcacagac gtaatcagaa tgatttcgtc
    24481 ggctaagaaa cgagaggttg cgacacgccc ggacgctttg ccacgaacga gcgtgacgga
    24541 aattttcgtg gagctatgtc tacttttcaa aataggcgaa ggagggaaca agatggcaaa
    24601 acaaaaaatt cgtatccgtt taaaagcgta tgaacaccgt attttagatc aatcagcgga
    24661 taaaatcgtg gaaactgcaa aaagaactgg agctagcgtg tctggtccaa ttccattacc
    24721 aactgaacgc agtctttaca caatcatccg tgcgactcat aaatacaaag attcacgcga
    24781 acaattcgaa atgcgtacac acaaacgtct tatcgacatt gtgaacccaa caccaaaaac
    24841 tgttgatgct ttgatgaagc tagacttacc atctggtgta aacatcgaaa tcaaattata
    24901 aaactaaaac aaaaataatg gaggtgtact catgaccaaa ggaatcttag ggaaaaaagt
    24961 gggaatgaca caaatcttca ctgaatctgg tgaattaatt ccagtaactg ttgtagaagc
    25021 tactccaaac gtagtactac aagtgaaaac aatggaaacg gatggctacg aagctattca
    25081 agttggttac caagatatgc gtgaagtttt atcaaacaaa cctgcgaaag gtcatgttgc
    25141 aaaagcaaac acggctccta agcgcttcat tcgtgaattc aaaaatgttg agctaggaga
    25201 atatgaagta ggaaaagaaa ttacagtaga tgttttccaa gcaggagaca ttattgatgt
    25261 aacaggtact acgaaaggta aaggattcca aggggttatc aaacgccacg gacaaagccg
    25321 cggaccaatg gctcacggtt ctcgttacca tcgtcgtcct gggtcaatgg gtccagttgc
    25381 acctaaccgt gtatttaaaa acaaacgtct tgctggccgt atgggtggca accgcgtaac
    25441 tatccaaaac ttggaagttg tacgtgtcga tgcagaaaga aatgttatct tgatcaaagg
    25501 taatgttcct ggagctaaaa aatctttaat cactatcaaa tcagctgtga aagctaaata
    25561 attgtaggaa gaaaggagga actaaggaat gccgaatgta gcattattca aacaagatgg
    25621 aagccaaaac ggtgaaatca cacttaacga agaaatcttc ggaattgaac ctaatgaaag
    25681 tgttgtttac gatgcaatcg taatgcaacg tgcgtcatta agacaaggaa cacacgcggt
    25741 taaaaaccgt agcgctgttc gtggcggtgg acgtaaacca tggcgtcaaa aaggaacagg
    25801 tcgtgcacgt caaggatcta tccgctcacc acaatggcgt ggaggtggcg tagtctttgg
    25861 accaacacca cgttcttaca gctacaaact tcctaaaaaa gttcgtcgtt tagcaatgaa
    25921 atctgtattg tcagaaaaag ttgctgaaaa caacttggta gcaatcgaag gcttgaactt
    25981 cgacgcacca aaaacaaaag aattcaaaca agttcttgct aacttatcta tcgactctaa
    26041 agtattggtt gttctagaaa aaggtaacga ctttgctgct ttatcagcac gtaacttacc
    26101 aaacgtttct gtagtaactt ctgataatgt gagtgtgcta gacgttgtat caaatacaaa
    26161 agtgttagca acacaaactg ctcttactca aattgaggag gtgcttgcat aatgaactta
    26221 ctagacgtaa tcaaacgccc agtgatcact gaaaaatcaa tgcttgccat ggatgacaag
    26281 aaatacactt ttgaagtgga cactcgcgca aacaaaactt tagtaaaaca agcggtagaa
    26341 gctgcttttg acgttaaagt caaaaacgtg aacatcgtga acgtacgtgc gaaattcaaa
    26401 cgtatgggca aatatgcagg atatacaaaa aaacgtcgca aagcgatcgt tacattgact
    26461 gaagattcaa aagaaatcca attattcgaa gctgctgaat aagcactaat agataactca
    26521 ttaaattagg agggaaaaac gtggcgatta aaaagtacaa acctacctca aatggtcgtc
    26581 gtaacatgac aggttctgat tttgctgaaa tcacaacatc aacacctgaa aaatcattgt
    26641 tacaaccatt gaaaaaccat gctggacgta acaacaacgg ccgcatcact gtacgtcatc
    26701 aaggtggcgg acacaaacgc caatatcgcg tgatcgactt caaacgtaac aaagataacg
    26761 ttgttgcaac tgttcaaacg atcgaatatg atccaaaccg ttcagctaac atcgcgttag
    26821 tacactatga agatggagtg aaagcttaca tcttagcacc taaaggacta gaagtgggta
    26881 tgaaacttgt ttcaggtcca gaagcagata tcaaagtcgg aaatgctctt ccattagaaa
    26941 acattccagt tggtactgtt atccacaaca ttgaaatgaa acctggtaaa ggtggacaat
    27001 tgatccgttc tgctggtaca agtgctcaag tacttggtaa agaaggcaaa tacgtattga
    27061 tccgcttgaa ctctggtgaa gttcgtatga tcttagctgc atgccgtgct acaatcggtt
    27121 ctgtaggtaa cgaacaacac gaattaatca acatcggtaa agctggacgc tctcgttgga
    27181 tgcgtaaacg cccgactgta cgtggtagcg taatgaaccc taatgatcac ccacacggtg
    27241 gtggtgaagg taaagctcct atcggacgta aagcaccagt ttctccttgg ggtcaaccag
    27301 ctcttggtta caaaactcgt aacaaaaaag ctaaatcaga caaacttatt gttcgtcgtc
    27361 gcaaaaataa ataattactt tgaccatgtg tcgcacattt tgagaggagg ttcaccatgg
    27421 gtcgtagttt aaagaaagga ccttttgtcg atgagcattt aatgaaaaaa gttgaagctc
    27481 aagcaggggt tgaaaagaaa aaagttatca aaacttggtc acgccgttca acagttttcc
    27541 caagttttgt tggatatacc atcgcagttt atgatggacg taaacatgta ccagtttaca
    27601 tccaagaaga catggtagga cacaaattag gtgaatttgc acctacaaga acttatcgtg
    27661 gacatgctgc tgacgataag aaaacgaaac gctaatttga ggggaggata aatccaaatg
    27721 gcagaacaaa tcacatcagc taaagcaact gcaaaaacag ttcgcacttc acctcgaaaa
    27781 gcccgtttag taattgacct tatcagaggt aaaagtgtcg cagatgcaat ttcaatcttg
    27841 aaattcacac caaacaaatc tgctggaatc attgaaaaag tattgatgtc agcagttgcg
    27901 aatgcagaaa ataactttga cttagatgtt gaaaacttgg tagtaagcga agcttttgtt
    27961 aacgaaggac ctacaatgaa acgtttccgt cctcgtgcaa aaggatcagc ttctccaatc
    28021 aacaaacgta caagtcatat cacggtagtc gtatcagaaa aataaggagg gataatcagt
    28081 gggtcaaaaa gtacatccaa ttggaatgcg tgtaggcatc atccgcgact gggatgctaa
    28141 atggtatgct gaaaaagagt atgctgagtt cttacacgaa gatttaagaa tccgtaaatt
    28201 tatttcaact aaacttgctg atgctgctgt atcaacagtt gaaatcgaac gcgcaacagg
    28261 tcgcgtaaac atttcaattc acacagctaa accaggtatg gttattggta aaggcggttc
    28321 tgaagtcgaa agcctaagaa aagaattaaa caaattaact ggtaaaagaa tccatatcaa
    28381 tatcgtggaa atcaaaaaac cagatctaga tgcaaaatta gtaggtgaag gaatcgcacg
    28441 tcaattagaa aaccgtgttg ctttccgtcg cgctcaaaaa caagccatcc aacgctcaat
    28501 gcgtgctggc gctcaaggga tcaaaactca agtatctggt cgtctaaacg gagcagatat
    28561 cgctcgttca gaaggatact cagaaggaac tgttcctctt catactttac gtgcggacat
    28621 tgattacgca tgggaagaag cagatacaac atacggaaaa ctaggagtta aagtgtggat
    28681 ctatcgtgga gaaattcttc caactaaaaa aaacactgag aaaggaggga aataatcatg
    28741 ttagtaccta aacgtgtaaa acaccgtcgt gaattccgcg gaaaaatgcg cggggaagct
    28801 aaaggcggaa aagaagtagc attcggtgaa tacggtttgc aagctgttga ttcacattgg
    28861 atcacaaacc gccaaatcga agctgctcgt atcgcaatga ctcgttacat gaaacgtggt
    28921 gggaaagtat ggattaaaat tttccctcac aaatcttata ctgccaaagc aattggggta
    28981 cgtatgggtt ctggtaaagg ggcacctgaa ggatgggttg caccagtaaa acgtggtaaa
    29041 atcatgtttg aaatcgcagg cgttcctgaa gaagtagctc gtgaagcgtt acgtctagct
    29101 tctcacaaat taccaatgaa aactaagatc gtaaaacgtg aggaaatggg tggtgaatcg
    29161 aatgaaggtt aaagaaatca gagaattaac cactgccgaa atgcttgatc aagaaaaaca
    29221 attaaaagaa gaattgttta atcttagatt ccaattagca acaggtcaat tagaaaacac
    29281 tgcacgtatt aaagaagtac gtaaatcgat tgcacgcatc aaaactgtgt tgcgtgaaca
    29341 agctaagtaa ttatggaagg aggccattaa gcgtatgact gaaggaagaa atcaacgcaa
    29401 agtttatcaa ggtcgcgtgg tttcagacaa aatggataaa acaattaccg ttgctgtcga
    29461 aacaaagaaa aaccacccta tctatggcaa acgcatgaac tattctaaga aatacaaagt
    29521 gcatgatgaa aacaacacag caaaagttgg cgacatcgtg agaattatgg aaactcgtcc
    29581 attatcagct acaaaacgtt tccgtttgtt ggaagtagtc gaagaagcag ttattatcta
    29641 ataacacgag attttcctat atagattgaa tgcaaaatct gaaaggagga tacacaacgt
    29701 gatccaagca gaaagtcgtt taaaagtcgc tgataactca ggcgcacgtg aaattttgac
    29761 gatcaaagtc cttggtggat ctggtcgtaa aactgctaac atcggtgatg tgatcgttgc
    29821 tacggttaaa caagcaacgc caggtggggt tgtcaaaaaa ggtgacgtcg ttaaagccgt
    29881 tatcgttcga acaaaatcag gagctcgtcg tacagacggt tcatatatta aatttgatga
    29941 aaatgctgca gtgattattc gtgatgataa aagccctcgt ggaacacgta tctttgggcc
    30001 agttgcacgt gaactacgtg aaaacaactt catgaagatc gtttcactag caccagaagt
    30061 tttataatct tgagacactt atcaaaggag gtgcgaaaca gttatgtttg ttaaaaaagg
    30121 cgataaagtt aaagttatca ctggaaaaga caaaaacaaa gaaggcgttg tactagcagc
    30181 gttcccgaaa aaagataaag ttattgtcga aggtgtaaat gtcgttaaaa aacaccaaaa
    30241 accttctcaa gctgctcctc aaggtggaat tgttgagatg gaagcgccaa ttcatgtttc
    30301 taacgtgatg gtggttgact ctactggtgt agctggccga gttggctaca aagaagtaga
    30361 cggcaaaaaa gtccgtgttt ctaaaaaaac cggtgaagtt ttagataaat aaaagtttaa
    30421 ggaaggaggg tcttactgaa tgaaccgcct aaaagaaaaa tatcttaaag aagtaactcc
    30481 atcattgatg gaaaaattta actatagctc tgttatgcaa acacctaaag ttgaaaaaat
    30541 cgtcatcaac atgggtgttg gtgatgcggt atcaaacgct aaaaacttag ataaagcagt
    30601 tgaagaatta actttgatca ctggtcaaaa accaatgatt acaaaagcta aaaaatcaat
    30661 cgctggattc cgtttacgtg aaggaatgcc aattggtgca aaagttacat tgcgcggaga
    30721 aagaatgtac gaattcttag acaaattggt ttctgtttca ctaccacgtg tacgtgactt
    30781 ccatggtgta agtaaaaaag cctttgacgg tcgtggaaac tatactttag gtattaaaga
    30841 acaattgatc ttcccagaag tagattatga tttagtagat aaagtacgtg gtatggacat
    30901 cgttattgta acaacagcaa actctgatga agaatctcgt gagttgttga cacaattagg
    30961 catgccattc caaaaataat taaaggaggc gaactacgtg gctaaaaaat caatgattgc
    31021 taaaaacaaa cgtcctgcaa aattttcaac acaagcttat actcgttgcg aacgttgcgg
    31081 acgtccacat tcagtttatc gtaagttcca tctttgccgt atttgcttcc gcgaacttgc
    31141 ctataaaggt caaattcccg gcgtgaagaa agctagctgg taaaaagtaa attcgcataa
    31201 gaaggaggta aaagatcaat ggtcatgaca gatccaattg cagattttct aactcgtatc
    31261 cgtaacgcaa acatggttaa acatgagtct ttagaagtac ctgcatcaaa aattaaacgt
    31321 gacatcgctg aaatcttgaa acgtgaaggt ttcgttcgtg atgttgaata catcgaagat
    31381 gacaaacaag gcgtgatccg tgttttccta aaatttggta aaaacggcga acgtgttatc
    31441 acaaacttaa aacgtatctc taaaccaggt ttgcgtgctt atgtcaaagc tgacgaagta
    31501 ccaaaagtat tgaacggttt aggtatcgca atcatttcga cttctgaagg tgttgtcact
    31561 gataaagaag ctcgtgaaaa aaatatcggc ggcgaagtta tcgcttacgt atggtaatca
    31621 agtagaatct acaaggaggt gtctttaagt gagccgtatc ggaaataaag tcgttgttat
    31681 ccctgaagga gtaacagtta ctcaagacgg aaacaacgtt acagttaaag gaccaaaagg
    31741 tgaattgact cgtacttttt cagcagatat caaaatgaat atcgaaggaa acgaagtaac
    31801 tttcactcgt ccaaacgaca gtaaagaaat gaaaacaatt catggaacaa ctcgtgcgaa
    31861 cttcaacaac atggttgtag gtgtcagcga aggtttccaa aaagcgttag aactaatcgg
    31921 ggttgggtac cgtgcacaat tacaaggatc aaaacttgta ttgaacgttg gttactcaca
    31981 tccagtagaa atcacaccac cagctggagt aactgttgaa gtaccagcta acacacaagt
    32041 aattgttaaa ggtgcgaaca aagaagaagt tggcgaatta gctgcaaaca ttcgtggaac
    32101 tcgtcctcca gaaccttata aaggtaaagg tattcgttat gttggcgaat atgtacgccg
    32161 taaagaaggt aaaactggta aataatcgtt tagaaaaatt gcatagaagc cagcagcagg
    32221 aaaaaggcat ttggctgaag tttaccttca aaaaaataca tttttacttg tgccgcagct
    32281 tctatttttc gaaacgtatt tactgcttga aatagtagta caataaaaat aaagaggtga
    32341 caattgtgat tacaaaacca gataagaaca aaacacgtca aaagagacat cgtcgtgtac
    32401 gtaacaatat ctctggtact gctgagcgcc cacgcttgaa cgtttttcgt tctaacaaaa
    32461 acatctacgc tcaaattatt gatgacgtag cgggtgtaac gctagcaagt gcctctacct
    32521 tggataaaga aatttcaggt ggaacaaaaa cagaagcagc aaaagctgtc ggtaaactag
    32581 ttgctgaacg tgcagctgaa aaaggcatta aagtagtagt ctttgaccgt ggtggatacc
    32641 tttaccatgg ccgtgtgcaa gctttagctg aagctgctcg cgaaaatgga ctagaatttt
    32701 agaagaagga ggaataccat tcatggttta tatcgatcca aaacatttgg aattagaaga
    32761 ccgcgttgtt gcaattaacc gtgtaacaaa agttgttaaa ggtggacgtc gtctacgttt
    32821 tgctgcttta gttgttgtcg gtgacaaaaa cggacacgta ggatttggta caggtaaagc
    32881 tcaagaagtt cctgaagcaa tccgtaaagc aattgaagat gcgaagaaaa acttagttga
    32941 agtacctatg gttggttcaa caatcccaca cgaagtaatc ggtgctttta gtggtggtag
    33001 aatcctaatg aaacctgctg tagaaggttc tggggttgct gctggtggac cagttcgtgc
    33061 cgtattagaa ttagctgggg tagcagatat cacttctaaa tctttaggct caaatacacc
    33121 aatcaacgtt gttcgcgcaa cagttgaagg tttgaaacaa ttgaaacgtg cagaagaagt
    33181 tgcagaactt cgcggcaaat cagttgaaga attaatcgga taaggaggac aacaataatg
    33241 gctgaattaa aagttacttt aaaacgcagt attatcggac gtcctcaaaa ccaacgcgat
    33301 acagttaaag cgttaggtct tacaaagatt aacagttcag tggttaagcc ttctaatgaa
    33361 gcaattaaag gcatgatcaa tactgtttct cacctagtgg acgttgaaga aatttaattt
    33421 agaaaaatca taactagaac attaaggagg tgccaaacct atgaaacttc atgaattaaa
    33481 acctgctgaa ggttcacgcc aagtacgtaa ccgtgttggt cgtggtactt catctggtaa
    33541 cggaaaaact gccggacgcg gacaaaaagg acaaaaagct cgttcaggcg gcggtgtgcg
    33601 tttaggattt gaagggggac aaacaccatt gttccgtcgt ttaccaaaac gaggattcac
    33661 aaacgtgaac cgtaaagact atgcagtcat taatcttgat gtattgaacc gctttgaaga
    33721 cggagctgaa gtaactcctg ttgctttagt tgaagctgga atcgtgaaaa acgaaaaagc
    33781 tggaatcaaa gtattagcta atggggaact aaacaagaaa ttaactgtga aagcagcaaa
    33841 attctctaaa gcagctcaag aagcaattga agcggctggt ggatcaatcg aggtgatcta
    33901 atgtttagac tattaaaaga tgcttttaaa gtaaaagaca ttagatcgaa aatcctattt
    33961 actgtatttg tgttgtttgt atttcgccta ggtgcacata ttactgtacc aggcgtaaat
    34021 gctgcttcat tgcaaaacct ttcttctttg ccatttttca acatgttgaa cttggtaagt
    34081 ggtagtgcga tgcaaaactt ttccattttc tcaatggggg tttcaccata cattactgct
    34141 tctatcgtca ttcagcttct tcaaatggac atcgtgcctc gatttgttga atggtcgaaa
    34201 caaggggaag ttggtcgtaa aaaactgaat caagcgactc gatatctgac attagtattg
    34261 gcatttatcc aatctgtcgg tatcactgct ggattcaatc aatacgctca attaggtttc
    34321 gtgaataatc ctaacgtagc aacttacgta acgatcggtt tgattctaac agccggtacg
    34381 atgtttgtta cttggctagg agaacagatc acagaaaaag gtatcggaaa tggcgtatca
    34441 atgatcattt ttgcaggtat catttctaga ttgcctgaaa gtatcagaga aatttatgaa
    34501 gattacttta taaatattga tccttcagac atatggaaat ctgctatttt tgtggccatt
    34561 ttactagtag cggtcttgtt gatcgtgaca ttcgtaacat ttttccaaca agctgaacgc
    34621 aagatcccga tccaatatac gaaacgcgta gctggcgcgc ctacaagcag ctatctgccg
    34681 ttgaaagtaa atgcagctgg agttattcca gttatctttg ctagttcgtt tattgctacg
    34741 ccaaatgctg ttttacaagc attgagcggt agattcggtt ctgaaaactg gtacaaagtg
    34801 atgatggaga tctttaacta taatacagca cctggtgcta cgatttatac gattctgatc
    34861 gttgccttca ctttcttcta cgcctttgtt caagtaaacc ctgagaaatt agcggaaaac
    34921 ttgcaaaagc aaggaagtta tataccaagc gtacgccctg gtaaggggac tgaagagtat
    34981 gtctcaagat tactgatgcg tttaagtaca gttggtgcag tcttccttgg tttagtggca
    35041 ttgcttccaa tcattgctca aatggtttgg gatcttccac aatcaatcag attaggcggt
    35101 acaagcttac tgatcgttat cggtgtagct ttagaaactg cgaaacagtt agaaggctta
    35161 atgctgaaac gtaaatatgt tggattcatt gagtaagaaa gcgtgttgag gtttcccctc
    35221 aacacacgtt ctcacacatt tattaggagg gaaaacaatg aacctcattt taatggggct
    35281 gccaggcgca ggtaaaggaa cacaagctga aaaaatcatt gatgcttatg gtattccgca
    35341 catctcaaca ggagatatgt tccgcgcagc gatgcaaaac gaaacagctc ttggcctgga
    35401 agcaaagtct tatatggata aaggtgcatt agttcctgat gaagtaacaa atggaatcgt
    35461 gaaagagcga ctagctgaac cagatacaga gaaaggcttc ttattagatg gctttccacg
    35521 tacgctagat caagcaaaag ctctggacgc aatgctaaaa gatttgaata aaaaaattga
    35581 tgctgtcatc gatatccatg ttggtgaaga aatcttggtc gaacgtctag ccggccgatt
    35641 tatctgcagc aattgtggag caacttacca taaaattttc aaccctacaa aagttgaaga
    35701 cacatgtgat cgttgcggtg ggcatgaatt ctatcaaaga gaagatgata aacctgagac
    35761 ggttaaaaat cgtctggcta tcaacatcaa aaatagtgaa ccaatcttgg cttattataa
    35821 agaacaaggt ttgctaaaca ctattgatgg tgctcgtgaa atcgatgctg tatttgcaga
    35881 tgtacaaaaa atcattgaaa aatagcacga ttgcccgtag ccgacttgca ttatgcagtt
    35941 actcttgtca agttcaataa attatgatag aatatgtcag tccgacttct agagaatcct
    36001 ctagatgatc cattttgaga attttgaggt gggaactgca gtttccgcca ttttatcgtg
    36061 tgaaaatgcg aaacaagtac aaggaggtac tgtgcgtggc aaaagaagat atgattgaag
    36121 tcgaaggtac agtcgtcgaa actttgccga atgcaatgtt taaagttgaa ctagaaaacg
    36181 gacaccaagt tcttgctact gtttcaggta aaattcgtat gcattacatc cgtatcttac
    36241 ctggtgacaa agtaacggtt gaattgtctc catacgatct taaccgtggc cgtattactt
    36301 atcgctttaa ataattgtac tccgtaaaac tacaggaggt attatcatga aagtaagacc
    36361 atcagtaaaa ccaatgtgcg aacattgtaa agtaattcgt cgtaaaggac gcgttatggt
    36421 gatttgccca gcaaatccaa aacataaaca acgtcaagga taattggagg tgctataaat
    36481 atggctcgta ttgcaggagt agatattcct cgtgataaac gtgtagtagt ttcacttact
    36541 tatatctatg gtattggtaa cactactgct aaaaagatct tagctaatgc tggtgtatct
    36601 gaagatgttc gcgttcgtga attaacgaat gaacaaacag atgctatccg tgcagaagta
    36661 gataaattaa aagttgaagg ggatcttcgt cgtgaagtga acttgaacat caaacgtttg
    36721 atggaaatcg gttcttaccg tggaatccgt catcgccgtg gattgcctgt tcgtggacaa
    36781 aacacgaaaa acaatgcacg tactcgtaaa ggcccagctc gcgctatcgc tggcaagaaa
    36841 aaataattct taagtgaagg aggttaaaac ttcatggcag caaaaaaagt gaatcgtaaa
    36901 cgccgtgtga agaagaatat agaagcaggt attgcacata tccattctac attcaataac
    36961 actatcatca tgatcactga tactcacgga aatgcattag cgtggtcatc agctggttca
    37021 ttaggtttca aaggaagcaa aaaatcaact ccttttgccg ctcaaatggc agcagaaact
    37081 gctacaaaag cagcaatgga acacggatta aagactgttg aagtaacagt taaaggacct
    37141 ggttctggac gtgaagcagc aattcgttca ttacaagcta caggtttaga agtgactgca
    37201 attcgtgacg tgactccagt tcctcataat ggtgcccgcc ctccaaaacg ccgtcgtgtt
    37261 taatgagtgc cgctcattct gagttttatc agtaacgtca ttgaacaaga cacttttcgt
    37321 tttgaaaggg gtaaagataa gaatgattga gttcgaaaaa ccaagaatcg caaaaattga
    37381 tgaagaaaaa gattatggca agttcatcgt tgaacctctt gaaagagggt atgggactac
    37441 tttagggaat tccctacgtc gtattttatt atcttctttg ccaggtgctg ccatcactaa
    37501 tattcaaatc gatggtgtac tgcatgaatt ctctaccatc aaaggtgtta gagaagacgt
    37561 cactcaaatc atcttgaaca ttaaaggctt agcgctgaaa atgtatggcc aagaagaaaa
    37621 aacccttgaa atcgatatta ccggacctgc tacagtaact gctggcgata ttatcgttga
    37681 tagtgatgta gaaattctta acaaagatat gtacatctgt agtgtctctg aaggagctac
    37741 gttccatgct cgcttaacag tgaaacctgg acgtggttat gttcaagcag atgaaaataa
    37801 aaaagaagat atgccaattg gcgttcttcc agtcgattca atctacacac ctgttcgtcg
    37861 tgtgaactat caagttgaga acacacgtgt tggacaccgt gaagattttg ataaattgac
    37921 gatggagatt tggacagatg gttcaattga accgttggaa gcaatgagtt tgtctgcgaa
    37981 aatcatgact gaacatttgg atatttttgt gaacttaact gatgaagcaa aaaatgctga
    38041 aatcatggtc gaaaaagaag aaacacaaaa agaaaaaatg ttggaaatga cgatcgaaga
    38101 gttagacttg tctgttcgct cttacaattg tttgaaacgt gcaggaatca atactgtaca
    38161 agaacttaca aataaatctg agcctgaaat gatcaaagtc cgtaacttag gacgtaaatc
    38221 attagaagaa gttaaagcaa aattgcacga cttaggttta ggtttacgta aagaagatta
    38281 aaacctttta cgaaggaggg aaaccaacgt gagttatcgt aaactaggac gcacatctag
    38341 ccaacgtaaa gcgatgttgc gtgatttaac aactgattta ttaatcaacg aacgtattgt
    38401 gactactgaa gctcgtgcga aagaagttcg ctcaactgca gaaaaaatga tcactttagg
    38461 taaacgcgga gatttgcatg cacgtcgtca agctgcggct ttcgtacgta atgaagttgc
    38521 cagcgtgcgt gaagaaaatg aggacatcgt cattgaatca gctttacaaa aactgttcaa
    38581 cgatattgca cctcgttacg cagaacgtca aggcggatac acacgcattt tgaagacaga
    38641 accaagacgc ggtgatggtg caccaatggt tgtcttagaa cttgtctaaa atcacactaa
    38701 taacatcact ttatagatga ttcttttaga gtgttatgat gttggaagat atttttccga
    38761 gtctagctca gcgctgctcc tcaagcgaat atcgcttggg gagtaagcac tcatcataaa
    38821 gtgttttttt ataccttcaa ttacctgtca tgacagatat gtttgaaggc ataaaaaaac
    38881 attttaagcg agaaataatt gaaaattttg tctttttttg atagtgttag taggaacttt
    38941 aggatgaaga aggagtaatc atggagccaa ttattgaatt agaaaagata aattataaat
    39001 accagccaga tgatcttcgc cccgcattga aagatgtctc ctttacaatt gataaaggtg
    39061 agtggatcgc tattattgga cacaatggtt caggaaaatc gacacttgcc aaaacgatca
    39121 atggattgct tctgccagaa tcagggatcg tgaaagtggg aaatcaaata ttggatgaag
    39181 aaaatatttg gacgatccga cagatggttg gaatggtttt tcaaaatcca gacaatcagt
    39241 ttgttggttc gacagtagaa gatgacgttg cttttggtct tgaaaatcaa gggattccca
    39301 gagaagaaat gctagtgcgt gtgaaagatg cacttgagaa agttagaatg gctgagtttg
    39361 cttcacgcga gcctgctcgt ttatcaggag ggcaaaaaca acgtgttgcc attgccggcg
    39421 tggttgcctt acgacctgat atcattattt tagatgaagc aaccagtatg ctagatccag
    39481 aaggtcgtga agaagtgatc tctacgatca agaagatcaa agaagaaagt caattgaccg
    39541 ttatatctat cactcatgat attgatgaag cagctaatgc caatcggata ctagtgatga
    39601 gacaaggcga acttgtccgt gaaggtacac caaaagaaat tttttctgct ggtcctgaac
    39661 tgatcgactt aggtctagat ctaccatttc ctgaaaaact gaagagcgca ctgaaagaac
    39721 gtggggttga tgtgcccagt gaatatatga cagaagaaag gatggtggat tggttatgga
    39781 catccgtttt gaacaagtag acttcactta tcagccgaat acaccatttg aacaaagagc
    39841 cttatttgac atcaatatga cgatcaaaga aaacagttat actgcattag tagggcatac
    39901 cggaagcggg aaatcaacct tacttcagca tttgaatgcg cttgttaagc caacaagcgg
    39961 tacagtccat attggagaac gagatattca gccggatacg gataataaga atttaaagcc
    40021 catccgaaaa aaagttggca tcgtctttca gtttccagaa gcacagctat tcgaagaaac
    40081 ggtagcaaaa gacattgctt tcggtcctaa aaactttggt gtcagcgaag aagaagcact
    40141 agtcctagca aaagaaacat tagaacaagt tgggctggat gaaagctatt tggaacgttc
    40201 gccatttgaa ctttcaggag ggcaaatgcg tagagtagca atcgctggtg tgcttgccat
    40261 gaggccggaa gtacttgtat tggatgaacc aacggcagga cttgatcccc agggtagaaa
    40321 agaaatgatg gagatgtttt ggcgtcttca taaggaacag cagatcacta ttgtattagt
    40381 tacgcattta atggatgatg tagccaattt tgcagattat gtctatgtgt tggaaaaggg
    40441 acgaatcgtt aatagcgggg agccgcaaga ggtctttcaa aacattgaat ggctaaaaga
    40501 aaaacaacta ggcgtaccta ctgccaccga gtttgcagaa gaattaatgg ctaaagggat
    40561 gaactttgct accttgcctt tgacagctga agaattagca gacgctatcg tccattatgc
    40621 tggaggaaat gcccatgatg aataaattga tatttggtcg ttatatgcct ggagattcct
    40681 tgatccatcg attggatccc cgagctaaat tattagccag tttttatttt atcggaatca
    40741 tttttttagc aaataattgg gaaacgtacc ttttgttggc atttttcaca ttactttctg
    40801 tcttcttgtc aaaagtagat ttgaaatttt ttatccgagg cattcgccca ttgatctggc
    40861 taatcctctt cactgtagct ttgcaggtct tgtttacaag tggcggagaa acttattgga
    40921 gttggggtgt tttccatatc actgaatttg gtgtgatgaa cggcctcttt attttctgtc
    40981 gattcgtgtt gatcattttt atgtcgactc tactcacgct tactacaccg cctttggaat
    41041 tatcggatgc gattgagtac ttgcttcgtc cattgaaagc cgtacggttc ccagtccacg
    41101 aaatttcatt gatgctgtcg attgctcttc gttttgtgcc tacattgatg gacgaaacag
    41161 aaaagatcat gaacgctcag cgcgctcgcg gtgttgattt tggtgaagga aacctagttc
    41221 agaaaatgaa agcagtcatt cctttgctga ttcctttatt tgtcagcagc ttcaaccgtg
    41281 cggaagatct tgcgactgct atggaagcaa gaggctacaa aggtggggaa ggaagaacga
    41341 aatatcgtgt attgcattgg cataatagag acacgatggt tatcattgct tttgtattat
    41401 taactgtgct actgatcttt ttaagaggat aaacgttcag tgggccgcta tctattcttt
    41461 tcttgctgat ctgtttgcaa gaaaggatgc gagcagtgta tgacaagaaa tattagggtc
    41521 tgtggcagac taaggtcaca ggcctctttc ttttatctga aaagaaagaa cgaaaaaatt
    41581 ttataaaaaa atcattattc cagataacct tttaggaaca aaggagagaa aaacatggta
    41641 cgttacaaag caatcattgc atacgacgga acaaatttta atggattcca aaaacagcca
    41701 aatgggcgta ctgttcaaga agaagtagaa aaaacattac aaaaaatggc aaatggaaaa
    41761 gaaatcacgg tctttggttc gggaaggaca gatgccggag tacatgcgat tgggcaagta
    41821 atccattttg attatccaga ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc
    41881 cagtcaccag aggatattgc tgtaagacaa gtagaaattg tttcagaaga cttccacgca
    41941 agatatttgg tcaaagaaaa gacgtatcaa tttcgagtgg atatagggaa accacgcagt
    42001 ccttttcgac gccattatgc aagttatttt ccttaccctc ttgatttgga aaaaattcag
    42061 cgggcgcttc ctgatttatt agggactcac gatttcacct ctttttgtgc atcaggaagc
    42121 tcgatagagg ataaagtacg tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa
    42181 gacgaattgt tgtttacatt taggggaaat ggcttcttgt ataagatgat acggatctta
    42241 gtaggaacgc ttttgaaaat tggcaatggc cgattgcctg aagatagtat cccagatatt
    42301 attgcgaaaa aagatcgtaa tgcagcagga cctacagcac atcctgaagg actttatttg
    42361 tatgaagtga aatatgaata agaggttgtg acagaagtgg tcagcttcaa gaaataagaa
    42421 ggaatttacg aaaattactt ctcaaaattt tgcaaaattt cggcttattt tcgaaggagc
    42481 tacttctgga acaccgtgaa tcagaggttg tgaaaaagct gccctgcatc aagtaataag
    42541 aacaaccaaa caaaaatagc tcgtcatatt tttcgtttgg ttgggcttat taccgcagat
    42601 gcaagctttt gaacaccgtt taaggaagag gttgtgaaat cagcgttttg acctgagtat
    42661 tagagaaaca aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgaa
    42721 ggtcagctga ttgaacaccg tttaagaaag aggtcgtgag cctgtcattt aactctgagt
    42781 cacaagtaac aatttcaaaa aacagcttct catctttgat gaatatcgtg acttgtggac
    42841 gaggcgttga taagtgaatc atctttttgt tacctatttt ttctgtaacc aaaaaacgat
    42901 ggaacgttgt tttgattgcc cttaatgagg acagtcggaa caggtttgtc atttttatat
    42961 ttaaatggca caaatttttc taattatttg tcatttagcg ctgaaaattt ttgctattta
    43021 tctaaaaaag tgataactac ttaagatgaa gcagaatatt tacgccatac ggcatacaac
    43081 cgcgaaaaat ataaaaaaaa gaaaacgatt gaacgcgttt ttgcagtcgc aaaggaaaag
    43141 catggaatgc gctacatcaa gtatcgagac ttggaaaaca atcaggtgta tacgctgatt
    43201 gtttttgctg caatgaatct gaaaaagttg tccacttggc agttggaaca tatgtcttca
    43261 tatcttttat tatacaaaaa tagcaaaagc accagtctac actcttagta aagaggaaac
    43321 tgatcctttt gtctacattc ttaaagtact taaactaagt actttatttt actctttagg
    43381 attgatacag tagcatctat ccctttatta ataatctttt atttttttaa ataaagatgt
    43441 tgtctccatc ttcaggcact aaaacttttt cggaaattcc tttttcttta ttgaaagact
    43501 ttaattcttc tcttgacagt ccccaatggt ttacagcttc catatgaacg gcaataattg
    43561 tggaatctgg tattgcttta tgcaattcat ataaatcgtc tttccccata ataagagatt
    43621 ctccaactaa aaaatgatta tctccagcat ttgctactat gatttctgga ttatactgat
    43681 caatagtttg tttaacagct tcataccaaa ctgtatctcc tgtaaagtat agtgtcttct
    43741 cagtcgaatg tttgaaaaca ataccgcaaa cattacctac ataattcaag atttctcctc
    43801 tgccatgttt gccttttgtt ttaaccaatt gtatagattc aaaaactgtg tcttctcgta
    43861 gtacctccac atttttaaaa ccatatagtc gaatttcatt cgcatcattt tcatcttgca
    43921 caaataattt tatttcttta ggtaggacct ctttcgctat atcgtcccaa tgatctagat
    43981 gtaaatgtgt tacaataaca gcatcaatac cgttgataat atcttcgact ggcattggca
    44041 aatcaactag aggattcatt tgatcttttc ttggtgatgg aaaaggacct ttcgaaataa
    44101 atggtggaag tgttcctttt tccgctaaca ttggatcaat taaaaatttt ttacctccat
    44161 agtctaagat agctgttgca ttacgaatgt gatgtatatt cataaacgtt gtctcctttt
    44221 tgttgatatg aaatattttt agtataattc aattccatac aataaataaa ccgaacaaaa
    44281 aaagtctttt actattttta cttaatttat gaaaggttgt ttaccatgtt agaccaaaca
    44341 gatataa
//
LOCUS       DADVXB010000007        42124 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.007, whole genome shotgun sequence.
ACCESSION   DADVXB010000007 DADVXB010000000
VERSION     DADVXB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.007"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            85..813
                     /locus_tag="KB902_000281"
     CDS             85..813
                     /locus_tag="KB902_000281"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBB6807136.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            813..1067
                     /gene="purS"
                     /locus_tag="KB902_000282"
     CDS             813..1067
                     /gene="purS"
                     /locus_tag="KB902_000282"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBB6807137.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1069..1740
                     /gene="purQ"
                     /locus_tag="KB902_000283"
     CDS             1069..1740
                     /gene="purQ"
                     /locus_tag="KB902_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBB6807138.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            1741..3963
                     /gene="purL"
                     /locus_tag="KB902_000284"
     CDS             1741..3963
                     /gene="purL"
                     /locus_tag="KB902_000284"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBB6807139.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            3948..5387
                     /locus_tag="KB902_000285"
     CDS             3948..5387
                     /locus_tag="KB902_000285"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBB6807140.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            5410..6462
                     /locus_tag="KB902_000286"
     CDS             5410..6462
                     /locus_tag="KB902_000286"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBB6807141.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            6459..7037
                     /gene="purN"
                     /locus_tag="KB902_000287"
     CDS             6459..7037
                     /gene="purN"
                     /locus_tag="KB902_000287"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBB6807142.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7034..8569
                     /gene="purH"
                     /locus_tag="KB902_000288"
     CDS             7034..8569
                     /gene="purH"
                     /locus_tag="KB902_000288"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBB6807143.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            8585..9859
                     /gene="purD"
                     /locus_tag="KB902_000289"
     CDS             8585..9859
                     /gene="purD"
                     /locus_tag="KB902_000289"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBB6807144.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            9981..10895
                     /locus_tag="KB902_000290"
     CDS             9981..10895
                     /locus_tag="KB902_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6807145.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKARYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11028..12593)
                     /locus_tag="KB902_000291"
     CDS             complement(11028..12593)
                     /locus_tag="KB902_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6807146.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(12586..14043)
                     /locus_tag="KB902_000292"
     CDS             complement(12586..14043)
                     /locus_tag="KB902_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6807147.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYDYG
                     NDQKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14057..15073)
                     /locus_tag="KB902_000293"
     CDS             complement(14057..15073)
                     /locus_tag="KB902_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6807148.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15293..16381
                     /locus_tag="KB902_000294"
     CDS             15293..16381
                     /locus_tag="KB902_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBB6807149.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            16435..17961
                     /locus_tag="KB902_000295"
     CDS             16435..17961
                     /locus_tag="KB902_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBB6807150.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            17963..19168
                     /locus_tag="KB902_000296"
     CDS             17963..19168
                     /locus_tag="KB902_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807151.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            19425..20402
                     /gene="guaC"
                     /locus_tag="KB902_000297"
     CDS             19425..20402
                     /gene="guaC"
                     /locus_tag="KB902_000297"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBB6807152.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            20666..22090
                     /locus_tag="KB902_000298"
     CDS             20666..22090
                     /locus_tag="KB902_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6807153.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            22551..23660
                     /gene="pdhA"
                     /locus_tag="KB902_000299"
     CDS             22551..23660
                     /gene="pdhA"
                     /locus_tag="KB902_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBB6807154.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            23663..24640
                     /locus_tag="KB902_000300"
     CDS             23663..24640
                     /locus_tag="KB902_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBB6807155.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            24665..26308
                     /locus_tag="KB902_000301"
     CDS             24665..26308
                     /locus_tag="KB902_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBB6807156.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26316..27722
                     /gene="lpdA"
                     /locus_tag="KB902_000302"
     CDS             26316..27722
                     /gene="lpdA"
                     /locus_tag="KB902_000302"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBB6807157.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            27884..28159
                     /locus_tag="KB902_000303"
     CDS             27884..28159
                     /locus_tag="KB902_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBB6807158.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28165..28932
                     /locus_tag="KB902_000304"
     CDS             28165..28932
                     /locus_tag="KB902_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBB6807159.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29100..30929
                     /gene="typA"
                     /locus_tag="KB902_000305"
     CDS             29100..30929
                     /gene="typA"
                     /locus_tag="KB902_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBB6807160.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31190..32962
                     /gene="recQ"
                     /locus_tag="KB902_000306"
     CDS             31190..32962
                     /gene="recQ"
                     /locus_tag="KB902_000306"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBB6807161.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33076..33378
                     /locus_tag="KB902_000307"
     CDS             33076..33378
                     /locus_tag="KB902_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBB6807162.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            33381..34544
                     /locus_tag="KB902_000308"
     CDS             33381..34544
                     /locus_tag="KB902_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6807163.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            34570..37998
                     /locus_tag="KB902_000309"
     CDS             34570..37998
                     /locus_tag="KB902_000309"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBB6807164.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38019..39143
                     /locus_tag="KB902_000310"
     CDS             38019..39143
                     /locus_tag="KB902_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807165.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39133..39570
                     /locus_tag="KB902_000311"
     CDS             39133..39570
                     /locus_tag="KB902_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6807166.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            39554..39892
                     /locus_tag="KB902_000312"
     CDS             39554..39892
                     /locus_tag="KB902_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBB6807167.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40011..40571
                     /gene="rsmD"
                     /locus_tag="KB902_000313"
     CDS             40011..40571
                     /gene="rsmD"
                     /locus_tag="KB902_000313"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBB6807168.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            40568..41059
                     /gene="coaD"
                     /locus_tag="KB902_000314"
     CDS             40568..41059
                     /gene="coaD"
                     /locus_tag="KB902_000314"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBB6807169.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41049..42092
                     /locus_tag="KB902_000315"
     CDS             41049..42092
                     /locus_tag="KB902_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBB6807170.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT        13911 a         7223 c         9445 g        11545 t
ORIGIN      
        1 aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat ttgcttttaa
       61 tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga aggaaaagcc
      121 aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt agatcaagca
      181 actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt gaataatcaa
      241 atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca ttttattgaa
      301 caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct ggaagtggtt
      361 atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga aggtaaagaa
      421 ttcatcaaac caatcattga attctactat aaggatgacc agttggatga tccatttatc
      481 aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag tgagctgaaa
      541 gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt cggtttggtt
      601 ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct tgcggatgaa
      661 gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat ggacaaagac
      721 gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata taaccgtcta
      781 tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta tatgtaacct
      841 ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc catcgtatgg
      901 gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa cttgctgatg
      961 cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt gcaaatgtaa
     1021 atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat gaaatttgcg
     1081 gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt tcgcgagatc
     1141 atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg atttgatggg
     1201 gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc gattgctcgg
     1261 ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc agtattcggt
     1321 acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt actgagacga
     1381 aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc caagacggcc
     1441 tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca tggggaagga
     1501 aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca gattgccttt
     1561 acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac gaacaaagca
     1621 gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt gctaggatca
     1681 gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt gaccgtatag
     1741 atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat ctatgccgaa
     1801 tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg aagaatgcct
     1861 aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc ctataaaaat
     1921 tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca aggccctgga
     1981 gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa agcagaaagt
     2041 cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt tggcggaatc
     2101 atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc attgaggttc
     2161 ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc aggtatcggc
     2221 ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt tgatccttgt
     2281 tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca caaacatatc
     2341 cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc aaaaacaggt
     2401 cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga agaagaacag
     2461 caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct tgaagcgtgt
     2521 ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat gggagcagca
     2581 ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact tatattgaca
     2641 ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat gttatcggaa
     2701 tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat ccaagaacta
     2761 tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga cgggcaatat
     2821 cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt agctgaagat
     2881 gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt tcagcagtta
     2941 gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct gctgcagcaa
     3001 ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt acaaaccaat
     3061 acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac gaataaagcg
     3121 ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa aatcggagga
     3181 caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa gcccttggcg
     3241 atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg ggaattatcg
     3301 acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt tatttcagga
     3361 aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc aatgattggt
     3421 atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa aaaatcaggg
     3481 gatctaatct atatattagg taagacgttt gcagattttg atggcagtga attacaaaag
     3541 atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat tgaaaagaga
     3601 aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc tcatgactgt
     3661 tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca gctagggata
     3721 tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc aagatttgtg
     3781 ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga tgctgctgtt
     3841 ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga cggtcagatc
     3901 aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg tcttatgaag
     3961 tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca gacgccgcta
     4021 gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt gcaggtatcg
     4081 tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt tctgaggtat
     4141 tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga catgtacgtt
     4201 atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc aaatttcatg
     4261 atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc cttagaaaag
     4321 agttagagga aaatggggcg atcttccatt ctaactccga tacggagata ttgatgcatt
     4381 tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct ttgaatgaag
     4441 tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc gctttggacc
     4501 caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac gtgattgcct
     4561 cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc cagcctggtg
     4621 agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag gacacgcagc
     4681 tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac atcgcaggga
     4741 tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa tcgccagtaa
     4801 aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc ggttatgcgg
     4861 aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt gcccgaacat
     4921 ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta tctgctgtac
     4981 gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt cggggtacga
     5041 caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc catgtgagga
     5101 ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa acgcgtaaag
     5161 aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt gcagattctt
     5221 taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa gatgctccgt
     5281 attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta tatgactatg
     5341 aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag cagaccaaga
     5401 agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga tgtcgaagct
     5461 ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg tttaggtatg
     5521 atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca attaaaagag
     5581 ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc aatcgaagca
     5641 gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga tatcttagca
     5701 caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa tgatccgtta
     5761 cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa tatggcgctg
     5821 attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta tgatctagcc
     5881 ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac gatcaaccca
     5941 ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta ctctcttgtt
     6001 cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc agaattgaaa
     6061 aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc cttgcttccg
     6121 ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg gtttgtagaa
     6181 aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg ctcatggccg
     6241 attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat ggagatgtat
     6301 gaaatcttca atatgggcat cggtatggtc ctggcagtcg aagaatcgaa agtaaaagaa
     6361 atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa agtgatcgcc
     6421 aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct gtttttgctt
     6481 ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa ggattggaat
     6541 cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa cgtgcaactg
     6601 cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa aaagagtatg
     6661 aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta ttagctggat
     6721 atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc atcaatatcc
     6781 atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc tttgaagctg
     6841 gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat actggaccaa
     6901 tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct ttagaagaaa
     6961 aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt attgaaaatg
     7021 gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg ggattgtagc
     7081 attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag gaacaaagca
     7141 tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag ggtttcctga
     7201 aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc ttttaggaag
     7261 acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac caatcgactt
     7321 tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg tcgaaatagc
     7381 agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg cagcaaaaaa
     7441 ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac tttcagaatt
     7501 acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa aagtctttcg
     7561 tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg tggaagaaaa
     7621 agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt acggtgaaaa
     7681 tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt cgatcgcagc
     7741 agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg cagatgctgc
     7801 gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac acatgaatcc
     7861 ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt atgaagcaga
     7921 tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc tgccaacagc
     7981 agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata cacaagaagc
     8041 tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact ttgcgcagga
     8101 agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg tacaagatca
     8161 agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta agccgactcc
     8221 agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga aatctaatgc
     8281 gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga tgaatcgagt
     8341 cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg cagttttagc
     8401 tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac atggtataaa
     8461 agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata tggcgaataa
     8521 atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga gaggagtcgg
     8581 ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa gtaaaaaact
     8641 tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg ggatgacaaa
     8701 agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa tccattttgt
     8761 taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt taaatgggat
     8821 cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag cagcagctct
     8881 gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa tcccgacagc
     8941 taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag aaaatggtgc
     9001 gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg tggctaccac
     9061 agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat ttggggatag
     9121 tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc ttttggcgtt
     9181 tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc gggcatttga
     9241 taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac cgcaaatttc
     9301 aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt tgggaatgaa
     9361 agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta cgaaggaagg
     9421 accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag tcgttctttc
     9481 tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc gtacagtaga
     9541 gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg ccggttaccc
     9601 cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc tttctgttta
     9661 ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac gtctttattt
     9721 agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca ccgcgttaat
     9781 ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag ctgccaatag
     9841 cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac aaacataatc
     9901 ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt tgttgtgtat
     9961 ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat cagaaagcag
    10021 ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta aaagtgattg
    10081 agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat ggaaacggtg
    10141 aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga gaagatcttt
    10201 ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct aaaaaacata
    10261 tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg gatgctttac
    10321 ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg tttgatgaat
    10381 tggaacggtc aggaaaagct cgttattttg gcgtcagcaa tcaaaaacca atgcaaatcg
    10441 aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa tttggcttga
    10501 aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa gcaagtatcg
    10561 atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc caagcatggt
    10621 caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa ttccctgaat
    10681 taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact ggcttggctt
    10741 ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg atgaacgtag
    10801 ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa gattggtacg
    10861 aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca ggtcaaaagg
    10921 gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag atattctgtc
    10981 tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta gttatttttg
    11041 tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt tttcttaaat
    11101 aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc tgaaatacga
    11161 tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt cagataatcg
    11221 atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg acttaatgca
    11281 acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc tttgataaaa
    11341 tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga gggcagagca
    11401 gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc ggcgctgatt
    11461 gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt cttttctttc
    11521 aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg tgttcgagtt
    11581 ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt tttcgataat
    11641 gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag tttcgcttct
    11701 tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt ttcaagtatc
    11761 atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac aggaccaatg
    11821 gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt ttgggctacc
    11881 tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa tttgatgaat
    11941 cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa cttcaaataa
    12001 tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc taataatacg
    12061 gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa tgtttcactg
    12121 atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa ttcgaaaaca
    12181 agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac tgctttttct
    12241 attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc tgcctgtacc
    12301 tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat gagacgagtc
    12361 caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa aggcatttgg
    12421 atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc catctcacca
    12481 tctccagctt cgccgacata agtgattgga taataagaac caaggacagt tatttgttcc
    12541 cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata catgtttgtt
    12601 tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc cttctcggta
    12661 tttgctgtca atcgtgatag gtttttgatc atttccgtaa tcgtaataaa gaaggagacg
    12721 cttgtttacg ttgtaaagtc cgtagccgat actgaaatct gaatcgatcc ctttggctaa
    12781 ctctttacgt atttctgcca gtttttctgc agggatgcca atcccgttgt ctataacttt
    12841 gaattggatc atctcatcaa ttttgcatgt ggtaatacga ataaatcctt tgtgacggac
    12901 gtacttcgtt ccatggtata cagcattttc aatcaatggc tgcaagatca tttttaaaat
    12961 agaaacagga aaaagtgttt ctggtatatc gatcttatag tcaagcatat ggccgtatct
    13021 tatttttaag atgactagat aatcattgat atggctaatt tctttttcaa gaggaatcca
    13081 gtcttgtcct ttgcttaaag acgtacgaaa aaagccggaa agtgcatggg tcatagtcag
    13141 agcttcttca aagcagtctt gttcgatcaa agaaataatg gcatccaaac tgttataaat
    13201 aaaatgggga gtaatctgag cttgcaatac acgaacttca ctttgtgcta aatggtattg
    13261 tttcaaagcg ttctcccgta aagactggtt tagatcttcc gccattttat tcatgctagc
    13321 ggtaagtgtt tgtaattcca gtgtttccgg cagggttaaa cgaaagccaa ggttccctga
    13381 agaaagttgt tctgacatct cgatcagctg attgatcggt tcttggacct ttctctctaa
    13441 aaagcgacga ttctttttcg catagaaaaa aatggtacta agaactccaa gttccactat
    13501 tgttaataga atgagcgagc ggacaagtgt cgtatttttt ttgcttgcta agtcgatctc
    13561 cacacgaaca aaatcttgta agatatctga cagcagttga gtgacagaat ctacctgatt
    13621 gatgatctct tcattggtat ccataaaatc ttttgccaag atattattga tcagctcgtt
    13681 ttgataatct tccagtgtat cgatcgtacg tagcgataca tctaacgtac taatttcttt
    13741 aagtgtattt gtattatttt tgatctctcg aatatcattc ctaagttctt ctaggatatt
    13801 ttcctcattg aactcatcta cggttacttg gccagaaatc aagtcccaca tactttccaa
    13861 aactttttga tcaaccttca aagcaattgc atctgctttt tggatatttg cgatcgtctg
    13921 ttgataaatc aaaagctgtt gcgaatataa cagtatgctc agtagcaaag ggataacagc
    13981 aaatagaagc atggctttgt ttgcttgggc aaaaatctgt tttatgctta aattttttgt
    14041 catgatactt ctccagtcaa taatttctgg ttgggatgtt agctatattc tgctgggaaa
    14101 agacagtctc ggaaataaaa atatctttag gtaatgtttt tcctgtttga atatttccaa
    14161 aataacgagt aacggtattg gctacatacc agccgacatc aggtttacac tcgactacac
    14221 aattgacgat tcctgagcgt agcttctcga tcatatcttc ttgtccatca atagttacaa
    14281 tgatcaaatc ttctccaggt ttgattgatg tttcttttat cgcagctaaa gcaccgtgag
    14341 tcatttcatc actatggctg tataatacat cgatttcgga taaatcattt gtttctaaat
    14401 atcgtttcat ctggtctttt cctttcatcc gaataaaatc accgacaatt cggtgaacaa
    14461 tagtcatcgg aggtttatgg tcgatggttc catctttttt tagggttggt ttacgattga
    14521 ttgattccaa aaatccttcg gagcgtagct tggtcggtgt ggagttctct gaaccagcaa
    14581 gttctaggat tctgatttcc tgtttctttg aatttgtgaa gtgattgctg acaaataaac
    14641 ccgcccgatt tccttctgct ttgaaactgg ggccaatgtg ggtgacgaaa agctcgggat
    14701 cattcgtttg aatatgtctg tcgacaagta tgacagggat ccctgctcgc tttgcttctt
    14761 ttaatacaga gtcccacccg gattcttgca aaggagtaaa aatgatcata tccactttat
    14821 aggcaatgaa cgtccgtata tcttggattt gccgttcctg attcatgtag ccatttcggt
    14881 agagaacttg gtaatcttct ttttcaagcg cagtgataat tgattcagta tgctttttcc
    14941 gccagctact ctccgttcct gattgcgaaa aaccaacgac tagtgggtca ggtgcttcct
    15001 ttgtattagg tgtacacccc atcatttggt aagcgattac aacaagggct aaaaaaaata
    15061 aaacacgttt cactttaaat cactccatct ggatttgtta gtactatctt atcagataaa
    15121 agggaaaatc aaagtcaaaa ggaatcaatc gaaaaaaatc caagaaactt aaaaaaatcc
    15181 aagacaaaaa aagtacacct aaaaaattta aagtaaatcc cataaaaaaa tcaatgttaa
    15241 cgctttcttt attagctata ctcggtgtat caattgaaat gggggataaa aaatgaaaaa
    15301 caaatttaga aagattgttg ggactatcgc tattttgacc gcaagcattc tattaagtgc
    15361 gtgtggcaat tcaggatctg cagatgatag tacggggtat gtaggaatcg ctatgccgac
    15421 caaatcagca gaaagatgga tcgctgatgg gaacaacatg gtctcggaat tagaaaaact
    15481 gggttataaa acagatcttc aatatggaga agataaagta gaaaatcaag tagcacaaat
    15541 agaaaatatg attacaaaag gggtagatac acttgtgatt gcttctatcg atggttcggc
    15601 tttaactgat gtgttagcta aagcaaaaga agcagatatc aaggtgatcg cctatgatcg
    15661 tttactgatg aattcagaaa atgtcgatta ttacgcgact tttgataatt ttggagtagg
    15721 tgtatcgcaa gcagcttata ttgaagagca cttaggattg aaagaaggaa aaggaccatt
    15781 cacgattgaa ttatttggtg gctcgcctga cgacaacaac gcactaatca attacaacgg
    15841 agtgatgtct gttttacaac catatatgga caacggtcag ttggtcgtgc catctggaca
    15901 gacgagtttc agtcaaatcg ctacgcttcg ctgggatggt tctacggcgc aagcaaggat
    15961 ggataatctg ttaagcgcaa attatactga ccaaacattg gatgctgttt tgtcgccata
    16021 tgatccaata agtttaggaa tcatttcgtc attaaaaggc gtggggtatg ggagtgaaag
    16081 taaaccttta cctgtgatta ctggacaaga tgcgacagtt gctggcgtta aatcgatcat
    16141 tgccggggaa caaacacaaa cgatctttaa agacacacgt atcttagcaa aaaatacgat
    16201 tgaaatgatc aaagcaatca gtgatggaga agaggttccg gtcaatgata ctgaaactta
    16261 tgataatggg gtgaaaactg tccctacgta tttagcaaat acagtatctg tcgataaaga
    16321 taattatcaa gcagagctga tcgacaccga ttattataaa gaatccgatc tgaaaaatta
    16381 agaggaacca aacaaggaac taaagagatc taagtcagag agaggataag aattatggcg
    16441 gattgtattt taaaaatggc agatatcacc aaaaaatttt ctggaatccg agcgttagat
    16501 tgcgtgaatc tgatgattga acgtggggaa atccatgcat tgtgcggaga aaacggagcg
    16561 ggaaaatcaa cattgatgaa tgtcttgagc ggcttgtatc catatggctc ctatgacggg
    16621 gaaatctttt atgatggaaa gctgtgtcaa tttaaagatt tgaaagatag tgaagaaaaa
    16681 ggcatcgtca tcattcatca agaattagca ctaagtcctt atctttcaat aaaagagaat
    16741 atttttctcg gaaatgaaca agcagaaaga ggcgtgattg attgggaact gacagaaaag
    16801 aaaacatatg aactgctgaa taaagtcggt ttgtctatcg acccgaatct tctagtatcc
    16861 cagattggcg tagggcaaca gcaactagtt gaaatagcta aagcattatc aaaatccgtc
    16921 cgtctgttga ttttggatga gcctaccgct gcattgaatg aagaagaaag cgcgaatttg
    16981 ctgagattga tccgagagtt gaaagagcaa ggtgtaacct ccatcattat ttcacataag
    17041 ctgaatgaaa tcgtggatat cgcagatcga atcaccattt tacgggatgg acagacgatt
    17101 gagacactag aaaatgaaat gatcagcgaa gagcatatta ttcgcggaat ggtgggcaga
    17161 gatttagttg atcgttatcc tgaaagaaaa ccggatattg gagaagttta ttttaaagta
    17221 gaagactgga cggtctatca ccctcttgat cacgagcgaa tcataaacga ccacatcaac
    17281 ttgcatttga aaaaaggaga gattgtagga atagctggac tgatgggagc gggcagaact
    17341 gaattcgcta tgagtctatt tggacattct tatggaagca agatatccgg acgtatatta
    17401 aaggaagggg cagagatatc agttaagacc gttccttcag ccattgcaaa cggactcgct
    17461 tatgtctcgg aggaccgaaa atctttagga ctgaatctgc tgatggatat tcgggaaaac
    17521 gtgacgctga gcagtttgga taaaataagt caaaaaggag tattagataa agaaaaagaa
    17581 gtaactgagg cagaaaattt ccggaaaaag atgcgtataa aaacaaactc catccatcaa
    17641 attgtcagta gtcttagtgg tgggaatcaa caaaaagtcg ttttatccaa gtggctgatg
    17701 acacaacccg atattctttt tttggatgag ccaacccgtg ggatagatgt tggggcaaaa
    17761 tatgagatct acacgattat cgaagaaatg gcagcaaatg gcaaagctgt ctgtcttatc
    17821 tcttctgaac ttcctgaaat attagggatg tgtgatcgaa tctatacgat gaacgaagga
    17881 cgtattacag gagaagtctc gcgagaagat gcagatcagg aagtcttgat gaaattaatg
    17941 acgaaagaag aggtgggtta agttggaaca ggcaaaaaat cttacggata aaaaagagaa
    18001 aaaactaaat ttgaaaagta gagcagctga tctttttggt cgctacagca tggtgatcat
    18061 tttagcggga ctacttattg cgtttcaatt gatgacggat ggtattttct ggcgtccatt
    18121 gaatataact aaccttgttc tgcaaaatag ccatatatta gtactagctg cagggatgtt
    18181 attagttgtg ctcttaggtc atgtggattt gtcggtaggg tcagtgatgg cgtttgttgg
    18241 tgcaattgcg ggcatgatga tggtcaatcg ccaaatgaac ccgtggatga cagttatcgc
    18301 atgtcttgca gtaggcgggc tgatcggcgc atggcaaggt ttttgggtag cttatgcagg
    18361 gataccggcg tttatcgtga ctttagcagg attgctgatg tttcgtggac tgacacaagt
    18421 tgttctagga ggccaatctc tagcaccttt tccagctgtt ttccaaaaaa tgtctacggg
    18481 ttatttacca gacttaagcg aaggaagcag ccttcacttc ttgacattga ttttaggaat
    18541 gatcatcacg atcgtgttag ttgttggtca atggcgaaca agaaatcgtc ggaaaaatca
    18601 tttatttgaa gtggaatctc caacagcttt cttggtaaag gcggtattta cagcagtcgt
    18661 tgtactagga ataacttata tctttgcctc ttatcaaggg tatccgatta ttttgatcat
    18721 tcttggtttg atcgttgcag catatgggtt tttgacaaat aaaacagtag caggtcgaca
    18781 gatttatgcg acgggcggaa atcgaaaagc ggctgaacta tcagggatca aaacaaagcg
    18841 aatcacgttc tgggtattcg tcaacatggg agtcatggca gctttagctg gattagtttt
    18901 agctgctcga ttgaatgcgg caacacctca agcaggtaca tcgatggaac tggatgcaat
    18961 ggcggcagta tattttggtg gtgcttcgac ttccggcggc attggaacaa tcatgggtgc
    19021 gattgtcggt ggcttggtca tgggtgtatt gaacaatggc atgtcgattt taggcgtcgg
    19081 ggtagactgg cagcaggcaa tcaaaggatt gatcttgctt ttagccgttg tgctagactt
    19141 gtataataag aaaaaacgaa caacgtagga gaacgccggt tattcagaaa aaagactgtg
    19201 acaagacatt tgtcacagtc tttttttcgc taaaagcgaa cattcattgt ttcgtttgta
    19261 tagactaaaa ataatatatg tttttttacc attcgtataa attctctttt tgctcttgat
    19321 ttttttgctt aattgagtta aattacatag ggcgctaaaa aaagccttga ttaaattaat
    19381 aatgttcgtg ttttgctgga tgtgaacatc aggaggataa tgtaatgaaa gtatttgatt
    19441 acgaagatat tcaattaatt cctaataaat gtatcgtaaa tagccgttct gaatgtgata
    19501 caacggtcac attaggtaaa catacattca aaatgccagt agtgcctgcc aacatgcaga
    19561 cgattattga tgaaacaatc gcagaattct tagcggaaaa tggttatttc tatatcatgc
    19621 atcggtttga tgaagcagct cgaattccgt ttatcaaaaa aatgaaaaag cgtggattga
    19681 ttacctcgat cagtgttggc gtcaagaaag aggaatattc ctttatagag aagttggcag
    19741 aagaatcgct aaatcctgat tatatcacta tcgacatcgc gcatggacat gctaactcag
    19801 ttattgatat gattcagcat attaaaaaat atttgcctga aacttttgtg attgccggta
    19861 atgttggtac accggaagcc gtccgtgaat tggaaaatgc gggcgcagat gcaacaaaag
    19921 tcgggattgg tccaggaaaa gtatgtatta caaaaatcaa gacaggcttt gggactggag
    19981 gctggcaact ggcagctctt agatggtgtg cgaaagcagc tcgcaagccg atcatcgctg
    20041 acggtgggat cagaacacat ggcgatattg caaaatctgt ccgttttggt gcgacaatgg
    20101 tcatgattgg ttcattgttt gccggtcacg aggaatctcc tggcgaaaca aaagtcgaaa
    20161 atggaatcgt gtataaagaa tactttggtt ctgcttcaga attccaaaaa ggcgaaaaac
    20221 gaaatgttga aggaaagaaa atctggatcc aacacaaagg atctttgaaa gatacactag
    20281 tggaaatgca acaagacctt caatcatcta tttcttatgc tggaggaaga gatctggaag
    20341 ccattcgaaa agttgactat gtcatcgtga aaaattcgat ttttaatgga gacacaatct
    20401 aaaaaataaa taaaatatta ggatgttgtg aaaaagttgt cctgcattaa gtaataagaa
    20461 cagccaaaca aaaatagttc tttatatgtt ttgtttggct ggaattatta tcgcagatac
    20521 aagcttttga acatcattat tcagaataag ggactgtgat aagatttttg tcacagtccc
    20581 ttatgttttg caaaaaaagt ttttcttttt tctcgtaaat tcggtaaaat caaaagaaaa
    20641 aatagacaat agaaaagaga agcttatgtg ggaaaaagta gagaaaaaac aaggaccgat
    20701 ttatcgtcaa attatggaac agattatgag agaaatcgaa aacggaagga tcaatcctgg
    20761 aagtcaactt gaatcagaac gaaaactagg gcaacttttt ggtgtgaatc gttccaccgt
    20821 tgtccatgca ttggaagagc ttagggagct tggggtacta acgagcaaac gtggcagcgg
    20881 atggtttgtt aatcagactg aatgggggaa attcgctgtt ccaagaatcg attggcggca
    20941 aatgatctct cctcgttatg agcagacgga ctggtatgag caaaaaataa gagaagcaaa
    21001 gcagatccaa aaaacatcgt ttcttgattt atacgctagc gagatgccag atgagctttt
    21061 gccgaatttt gagtttcctt cttattctct tgaagaaatc ttagcggaag aaaaagaaat
    21121 ggatctttta ggctatactc cgttacgtaa caaaatcaaa cggtatttgg aaagtaaatt
    21181 tgaattggca ttttccccca accagcttct tgtgactggt ggcggtcagc aagcaatctt
    21241 tttgatttta caaacgattc tttcagctgg agaggggata gctgtagagt caccttcttt
    21301 tttttaccga ttacctcttt tcaaagcttc aggaacgcgt ttatttggga taccgatgga
    21361 tgaagaaggg atcgacttag aaaaactgaa agaatcgatc cataaaaata aattgaaagc
    21421 agtgcttatc aacccgaatt ttcaaaaccc tacaggaaaa gtgatgagtc aaaaacgacg
    21481 agaaaagcta gtagaattgt gtcgacagta tcggcttcca attattgaag acgatgtatt
    21541 tacggatctt tcatttctaa accaagaaga agtccttcct atacgaacga ttgatccgga
    21601 taatgtgtta tacgtcggtt cgttatctag ggttttagga aaaacaacga aaatcggttg
    21661 ggtgatagga cctgagactt ttatctcgca actagctcaa gcgcaagaaa tgatggagtt
    21721 ttcgatgaat atccttacac aaatcacagt ggctaatgta tttaatgaag caattgattt
    21781 gaaaatgcaa gatgtaagaa aaaagttgaa agaaaaaagc cgactgataa gcgcttgggg
    21841 agattcacaa tcgtttttca agcttcattc aattttaggt ggttactatg cctggattac
    21901 ttgggatggg aaaaaactag accccgaact agcagaaaaa gtagtagata tgggtcttgg
    21961 aattgcacca agtctacttt ttgggcaaga tataaatgga atcagaatca attacagtag
    22021 gctggatgaa aaccaaatac cgttgtttta ttcaaagatg aaaattctag aaaagtggtt
    22081 aacagaataa tttcacaaag taaatagatt aaagaatata acagcttgga tttaaatttc
    22141 aagctgtttc ttttttttcg gaaaaagaat acgatataaa gaaactaaga aaaaaccatt
    22201 atttgtacgt ccgttcacga tgtgtaaata aaataaatgt ttgcaacaaa actgtataac
    22261 accaacgttt ttaaatagaa acagatggtt gtaagtttga ttagaaaata gaaaaaatgc
    22321 agatgaaata taaaacgctt tccttattgt gattttattc actaatgctg ttaatatgcg
    22381 gattggcata atttcctttc atcgtgaaaa tttgtgcttt tagcttgtat ttctcataaa
    22441 tccatgataa tttattaatg aagacggtta aatagtgata cagttttatt cactgtttca
    22501 atcgcagaat gaagagattt tcttatagat gagagaggaa tgtgtgacaa atggcaaaca
    22561 aaaaagcacc gatcgacttc caagcactgc tagatgaagt caatgcagat ttcccagtat
    22621 atcaagcact tgatcaagat ggaaacgtag ttaacaaaga tttagtacct gatttatccg
    22681 atgatgaact cgttgaatta atgactcata tggtatggtc tcgtgtatta gaccaacgtt
    22741 caacagcgct gaaccgccaa ggacgcctag gcttttttgc accaactgct ggacaagagg
    22801 caagtcagct ggctagtgct tacgcatttg ataaagaaga tgttcttctt ccaggttatc
    22861 gggatgtacc tcaactagta aaacatggtt tacctttatc tcaagctttt ttatggtctc
    22921 gaggacatgc tgcaggtaat tcttatccgg aagaattgaa agctctacca ccacaaatta
    22981 tcatcggtgc acaatatgta caagcagccg gtgttgcatt aggtttgaag aaacgaaaca
    23041 agaaaaatgt cgtcttcact tatactggtg atggcggttc atcacaaggt gatttttacg
    23101 aagcaatcaa tttcgctggc gcttaccatg caaatgccgt attttatatc caaaacaacg
    23161 ggtatgcgat ctctacacct cgtgaaaaac aaactgcagc aaaaacactt gcacaaaaag
    23221 ctgtcgcagc tgggattcct ggtattcaag tcgatggaat ggatccgctt gcagtatata
    23281 ctgtatctaa aatggcacgg gaatgggcga tcagtggaaa tggaccagtc ctaatcgaaa
    23341 cactgactta tcgttatgga ccacatacac tatctggtga cgatccaacc cgctaccgta
    23401 caaaagacac agatgacgat tggcagaaaa aagatccatt gatccgcttc cgtaaatatt
    23461 tgacggaaaa aggactttgg tctgaagaaa aagaagaaca agtcatcgaa gcaactaaag
    23521 aagaaatcaa agcagctatt gctgaagccg acaaagtacc aaaacaaaag gtttcagatt
    23581 tcttgaaaaa catgttcgaa gtatctccac aatcaatcaa agaacaaatt gcaatttatg
    23641 aagcgaagga gtcgaaataa tcatggcaca aaaaacaatg atccaagcaa tcacagatgc
    23701 cttagcactt gaactagaaa atgacgagaa tgtcgttgtt tttggtgaag atgttgggaa
    23761 aaacggagga gttttccggg caactgaagg attgcaggaa aagttcggag aagaccgagt
    23821 attcgatact cctttagctg aatctggaat cgcaggattg agtttcggtc ttgcgttaga
    23881 aggatttcgt ccagttcctg aaatccaatt ctttggtttt attttcgaag caatggacga
    23941 agtagtagct caaatggctc gtacaagata tcgaatgagc ggcactagaa atctacccat
    24001 cacaattcgt tcgccatttg gtggcggtgt tcatacacca gaattgcatt cggataattt
    24061 agaaggtttg atcgctcagt ctcctggtat tcgagtagtg attccttcca acccttatga
    24121 tgcaaaagga ctattgattt cttctattag aagtaacgat ccggttgttt tcctagaaca
    24181 catgaaacta tatcgctcat tccgagaaga agtgccggat gaagcttacg aagttccttt
    24241 ggataaagca gcagttactc gtgagggaac agatgtatct attatcacat acggagcaat
    24301 ggtgcgtgaa gcaatcaaag cagcagacaa tcttgcaaaa gaaaatatat ctgttgaaat
    24361 cattgatctt cgtacagttg cgccattaga tgtagaaacg atcattcaat ccgtggaaaa
    24421 aactggtcgc gtagttgttg tccaagaagc acaacgacaa gcgggcgttg ccgcgcaagt
    24481 agtttctgag atctcagaac gcgctatcct ttcattagaa gccccaatcg gacgagtttc
    24541 tgcacctgat acagtcttcc catttggaca agcagaaaat gtctggttgc caaatgcaaa
    24601 agatatcgaa gacaaagtaa aagaaatcgc ggaattttaa gaaaagaagg gacgaaacaa
    24661 agtcatggct tatcaattta aattgccgga tatcggtgaa ggaatcgcag aaggtgaaat
    24721 cgtcaaatgg ttcgtcaaac caggagatac gatcaatgaa gatgatacat tactagaagt
    24781 tcaaaatgac aaatcagtag aagaaatccc gtcacctgtt acaggaacgg ttaaaaatgt
    24841 gattgttcca gaaggtaccg tagcaaatgt tggggatgta ttagtagaaa tcgatgcacc
    24901 aggacacgaa gacaatgaag gggacagtgg tgtagccgca gaatcccaaa ctccagctaa
    24961 accggctgct gaacccactg ttgatacaga atcagctgga tcgtcaagcg aaggagtctt
    25021 ccaatttaag ttaccggata tcggtgaagg aatcgcagaa ggtgaaatcg tcaaatggtt
    25081 cgtcaaacca ggagatacga tcaatgaaga tgatacatta ctagaagttc aaaatgacaa
    25141 atcagtagaa gaaattccgt cacctgtcac agggacagtt aaaaacgtga ttgttccaga
    25201 aggcactgta gcaaatgttg gggatgtatt agtagaaatc gatgctcctg gacacaatag
    25261 tgcaccgtca actagtgcgc catcagctga agcaccaaaa gaaaaagtgg aaacatcagg
    25321 ttcagcaagt gtcgttgaag ctgccgatcc aaataaacgt gtattggcta tgccatctgt
    25381 tcgtcaattt gcccgtgaaa aagatgtaga tatctcacaa gtaactgcaa ctggaaaagg
    25441 tggcagagta acaaaagagg acatcgaaaa cttcttggca ggtggtccaa gcagtgcacc
    25501 agcgaaatca gaagcgccag aagcggcagc accgaaagaa gcagctcctg cagcagaaag
    25561 caaaccagct gcaccagcaa aaccattcaa gtccaactta ggagacttgg aagaacgtgt
    25621 agcaatgacg ccaacacgta aagctatcgc taaagcaatg gtcaacagta agcatacagc
    25681 tccacacgtg acattgcatg atgaagtaga agtgtctaaa ctatgggata atcggaaacg
    25741 atttaaagaa gttgctgctg caaatggtac gaaacttact ttcttgccat atgtcgtgaa
    25801 agctttaaca gcgactgtta agaaataccc agtattgaat gcatctatcg acgatgcaaa
    25861 ccaagaaatc gtttataaac attactacaa tatcggtatt gcaactgata cggatcacgg
    25921 actatatgta ccaaatgtga aagatgcaga ccgcaaagga atgtttgcta ttgcagacga
    25981 aatcaatgag aaagcaaaat tagctcatga cggcaaacta tctgcagaag atatgcgcaa
    26041 tggaacaatt acgatcagca atatcggatc tgtaggtggc ggttggttta caccagtcat
    26101 caactatcca gaagtagcta ttttaggtgt aggaacgatt gcacaacaac caatcgtaaa
    26161 tgctgaaggc gaaatcgttg tcggtcgtgt gatgaaactg tcattaagtt tcgatcaccg
    26221 tatcgtagat ggagcaactg cgcaacaagc aatgaataat atcaaacgtc ttttagctga
    26281 tccagagcta ttaatgatgg aaggatgata aacaaatggt agttggagat tttgctgtag
    26341 aattagatac agttgtaatt ggtgcgggac ctggtggcta tgtagctgcc atccgcgctg
    26401 ctgaaatggg acaaaaagta gcaatcattg aaagagagta tattggcggt gtttgtttga
    26461 atgtcggctg tattccttca aaagcactga tagctgcagg acaccattat caagagtcac
    26521 tagattctga aatgtttgga gtaactagtg aaaacgtcaa actagatttt gcaaaaacac
    26581 aagaatggaa agaaaacaaa gttgtccata cgttgacttc tggtgttggt ttcctattaa
    26641 aaaaacataa ggttgaaaca atcgaaggag aagcgttctt cgtagatgat cacacactac
    26701 gcgtcattca tccagattca gctcaaactt attcgttcaa taacgcaatc atcgcaacag
    26761 gttcccgtcc aatcgagatt ccaggattta aattcggagg acgtgtgtta gattctactg
    26821 gcggattagc attgaaagaa gtacctaaga aatttgtgat catcggtggc ggtgtgattg
    26881 gtgccgaatt gggcggagcg tacgcaaact taggagcaga agtaacgatt cttgaaggct
    26941 caccacaaat tttaccaact tacgaaaaag atctagtaaa attagtagaa gatgatttca
    27001 agaaaaaagg cgtaacagtc gtaacgaatg caatggcgaa agaagcagtc gataacggtg
    27061 acagcgtgac agtgaaatat gcagtggacg ggaaagaaga atccgttact gctgattatg
    27121 tgatggtcac tgtaggtcgt cgtccgaata cagatgatat gggcttagaa caagcgggtg
    27181 tcgaagtagg agaacgagga ttgatcacgg tggataaaca aggacgtacg aacgtaccta
    27241 acatctatgc catcggtgat atcgttccag gggcggcatt agcacacaaa gccagttatg
    27301 aagcaaaaat cgctgctgaa gcaatctctg gcaaaaaagt agctgtagat tataaagcaa
    27361 tgccggcagt agccttcact gatcctgaat tggcttctgt aggtatgacg atcaaagaag
    27421 caaaagatgc tggtatcgaa gcaaaagcat ataaattccc attttcaggg aacggtcggg
    27481 cattatcgct tggtaaaaca gaaggattca tccgtctagt tacgacgatc gaagataacg
    27541 tgcttattgg cgcgcaaatc ggtggagtcg gcgcaagtga tatggtctct gaattagctt
    27601 tagcaatcga atcaggaatg aatgctgaag atatcgcctt gacgattcat cctcatccat
    27661 ctcttggcga aatcgtcatg gatgcttcgg aattagcatt aggtttacca atccatattt
    27721 gatttgaata atacaggcga aacgcaactg aaaaatcagt tgcgttttgt tttttagaat
    27781 tatcaataat attattatgt aaacttaaaa atatgacaac ttcttggttt attaccactt
    27841 cctatgctac actgaagagg aatatgaaat aggagagttg aagatgcaag aatatcagta
    27901 tccacttgat ttagattgga caacagacga aatggtcatt gtaatgaaga tgtgggaaga
    27961 tctggaacgt gcgaatgaaa aagggataaa caatgaagct tttttgaaga cttatcagca
    28021 gtttaaaact gttgtcaaat ccattggtga ggaaaaacga ttgggacggg aatttgaaaa
    28081 agcttccggt tattctttat atcgtacagt gcagcaagca aaaaaaaatc caaacaaaac
    28141 tttgagaatg aacgggtgag ataaatggaa cagatgattg atcatatcaa gtcctggctt
    28201 gaagaagctg gtgagaaaat caaatcttct caacaaacat taacaatctc gcaaaaatca
    28261 aatcgaacgg atctagtaac aaatgtcgat cgaaacatcc agaattttct aatcgaaaaa
    28321 atccattcct ttgatccaga ggcgaaaata ttggcagaag aagaagggtg taatcaatta
    28381 tcggatctcg atggaagagt ctttatcatc gatcctattg atggcacctt gaattttgtg
    28441 attgaagggg aaaatttttg tattatgctc gctgtttatg aatccggcgt tggaaagctt
    28501 ggtttcattt atgacgtgat gagaaatgaa cttttttggg gtggaaaagg aataggcgtg
    28561 tataaaaatg atgagccatt gcctagacca gcaaataaat ccttatcgga aggcttactt
    28621 ggtgtgaata gttatctttt cggtcataat aaatatggaa tccgagaaat tgcggaaagc
    28681 agcatgggga cacgtatgta cggatgcgct ggtcttgaac tagtggcaat cttgaaagga
    28741 aaccacattg cttatatttc aaaccttagc ccttgggatt atgcagcggg aaatgtctta
    28801 ttggaagagt ttggtatggt aacaagcggt ctttttggta ctcctttgac atttgaaaaa
    28861 agggaatact atttagcagg gacttcttgt gcatatgcag aaatcgcaga ccttttgaaa
    28921 aaagaaggct gaaaaaaagg tagaaatcat tcacaaaaat gataaaaacg agcaaaagat
    28981 taattttctc gaaaaaatga aaacatttta ctatatttca tgaaaaaagt ctgctataat
    29041 tagcagtcga gtaaaatttg ccctgtcata aagaaccaat aaaaaaggag ttagttacat
    29101 tgaattatag aaacgatatc cgtaacgtcg caattattgc ccacgttgac cacggaaaaa
    29161 caacattagt tgatgaacta ttaaaacaat cagatacatt agacgcacat acgcaattgc
    29221 aagaacgtgc gatggactca aatgcgctag aaaaagaacg tggtatcacg attttagcca
    29281 aaaacacagc tgtagactat aaaggtattc gcgtaaacat catggatact ccaggacacg
    29341 cggacttcgg tggcgaagta gaacggatca tgaaaatggt tgacggcgtt gtgttggtcg
    29401 tagatgcgta tgaaggaaca atgcctcaaa cacgttttgt attgaaaaaa gcactggaac
    29461 aacatatcac accaatcgtt gtcgtaaaca agattgacaa accttctgct cgtcctgagc
    29521 atgtcgtaga tgaagttctt gaactattca tcgaattagg agcagatgat gatcagttag
    29581 actttcctgt gatttatgca tctgcactaa atggtacgtc aagcttgtca gatgatccag
    29641 cagatcaaga accaaccatg gcacctattt ttgatacaat tattgaaaaa atccctgctc
    29701 ctgtcgataa cagcgacgaa ccattacaat tccaagtttc attacttgac tacaacgatt
    29761 atgtaggtcg tatcggaatc ggacgtgtat ttagaggaac aatcaaagta ggagaccaag
    29821 tagcattaat taaattagac ggaacagtta agaaattccg tgtaacgaaa ttatttggtt
    29881 tctttggact aaaacgtcta gagattcaag aagcaaaagc tggagacttg attgctgtct
    29941 caggtatgga agatatcttt gtcggtgaaa cagttactcc tgtggatcat caagatgcgt
    30001 tacctatcct tcacattgac gaaccaacat tgcaaatgac tttcttagtt aataattcac
    30061 catttgccgg tcgagaaggt aaattcgtaa ccgctcgtaa gattgaagaa cgtttgatgg
    30121 cagaacttca aacagatgta tccttacgag ttgaaccaac aaactctcca gatgcatgga
    30181 cagtttctgg tcgtggagaa ttgcatttgt ctatcttgat tgaaaacatg cgccgtgagg
    30241 gatacgaatt gcaagtatct cgtccagaag ttattgaaaa agaaatcgac ggtgtaaaat
    30301 gcgaaccgtt tgaacgcgtg caaatcgata caccagaaga atatatgggt agtgttatcg
    30361 agtccttgag cttacgtaaa ggtgaaatgc aagatatggt ccatacagga aacggacaaa
    30421 tccgtttgac attcttaaca cctgcccgcg gtttgattgg ttattcaact gaattccttt
    30481 caatgacacg tggttacgga atcatgaacc atacttttga ccaatatctg ccaatgcttc
    30541 ctggtcaaat tggcggacgt caccaagggg cgcttgtttc gatcgataca ggaaaagcaa
    30601 cgacttattc tatcatgagt atcgaagaac gcggtacagt cttcgtagaa ccaggtacag
    30661 aagtatatga aggaatgatt atcggggaaa acagccgtga taatgatttg actgtcaaca
    30721 tcacgaaagc aaaacaaatg acaaacgtac ggtctgctac taaagaccaa acatctgtca
    30781 tcaaaaaacc aaaacaattg acgttggaag aatctttgga attcttgaat gatgatgaat
    30841 attgcgaagt aacaccagaa agcattcgct tgagaaaaca aattttagag aaaaatgctc
    30901 gtgaaaaagc atctaaaaag aaaaaataat ctgtaaaagg atgaagagag aaaccagctt
    30961 gttataaaaa atagctggtt tctttttttg tccaactctt ttctgtggag aagtcatctt
    31021 tgtcaatgga cataaattca gaaaatacgc cgaaagacgt ttaaaagact tttaaaaaac
    31081 ttatttctag agagtttttg tttcataata agataatgtt tcacgaaagg agatcaactt
    31141 gtccttcgaa gaaaatcgaa gtaaaatggc aagagaaagg agcgggaaga tgaacgactt
    31201 attaaaacaa tactttggct atgatgagtt tagacctggt caaaaagaaa ttatccagaa
    31261 agtcattgat caggaaaatg tattaggaat catgcctacc ggaagtggga aatcaatctg
    31321 ttaccagctt ccagctttac tattagatgg gcttactgtg gttgtgtccc ctttaatctc
    31381 tttgatgaag gatcaggtgg acgcggcgaa tcaattaggt atacccgcca cttttatcaa
    31441 tagctcgtta gatggttacg aaacagctag acgcttccaa gaaatcgata gacagcagta
    31501 ccgtttactt tatatcgctc ctgaacgttt tatcatgccg gattttatcc aagcaatgaa
    31561 gcgatggaac gtccgtatga tcgctattga cgaggcacat tgtatctctc agtgggggca
    31621 tgatttccgc ccaagttatt tacagatggc gaaccagcta gatcaactgc caaatcgtcc
    31681 tgtaattgtt gctttgacag ctacagcgac tgtgcaagta gctgctgaca taaaaagact
    31741 tttaaaaatt ccagaaaaca accatattca gactggtttt gaacgagaaa atctacgatt
    31801 tcaagtaatt aaagatcaaa aaaaagaaca atatctaatc gaatatttaa agatcaacaa
    31861 aaatcaatct ggtatcattt atgcagcaac gagaaaagaa gtagaccgtc tctatcattt
    31921 gcttaaaaaa ttcgattttt ccgtgggtag atatcatggt ggtctaaatg agaatgagcg
    31981 aacagaaatg caagaagcct ttttatacga tcgcttgcag ctgattgtag cgacaaatgc
    32041 atttggtatg ggtataaata aaagcaatgt ccgttttgtt atccattatc aaattcctgg
    32101 ctctctagaa gcatactatc aggaagctgg tcgggcggga agagatggtc tttccagtga
    32161 agccatcctg cttttctctc ctcaagatat ccaagtccaa aagtttttta tccagcagtc
    32221 ccaaagagaa gaagggcaaa agcaaaaaga atatgaaaaa ttaaaagcga tgacagaata
    32281 cgtgtatatt gagtcctgtc ttcagcaata catcctaaac tattttggcg agacaagcag
    32341 tccgtgcaac cgttgtggta actgtttaga tgacagagaa atagtagaag taacgacaga
    32401 agcacagatg gttctttctt gcttaaaacg tatgggtgag aactatggta aacaaatgct
    32461 gatgaaagtc ttagcaggat cgaaagaaca aaagctgcaa gctttaggtt ttggacattt
    32521 atctacctat ggactgatga aaaaccaatc gcaaaaagaa acgatgcagt taattgaata
    32581 tttgatatcg aatggctatc ttctgaccat caatggtgag tatcctgttt tgaaagtaac
    32641 agaaagaggg atacaagtat tgaaaggaca agaatctgtt tatcgaaagg aacccaagaa
    32701 agtccagcag ctatcggatg aagaaaccga tacactattt gaagtgctgc gggaactgcg
    32761 aacggatcta gcatcagaag caggcgttcc cccgtatgtc gtattttcag attccacatt
    32821 gaaagaaatg agccgaatac gtccatcaag cagattggag atgcttcaga taaaaggagt
    32881 tggccaaagc aagcttgata aatatggcga agccttttta tctcggataa aaaatgcgga
    32941 ctctaacgtt ctggataagt agaaagaacg aatacgtaaa aatgaataaa aacaactggt
    33001 taaatctgtt ttttttgctc cttatgaaaa tcaaatatgt tataattaag gaattagaat
    33061 gggaggtaag cacagatgga ttctttgtcg aaaaaacttg cgatccaagt attaaatgat
    33121 gaagcagaac ggatcaaacg attaatccga aatcaaaaca acagtctctg tatctcacaa
    33181 tgcaaagcct tcgaagaagt ggtagataca cagatgtacg gcttttcccg gcaagtcggt
    33241 tttgctgtcc gtataggagt aatcggaaag aacgagggcc agctgatgtt aagtgagcta
    33301 gaacgagaat tgaatcagtt atatagtgag gtttaccaag aaatttatga taaaaaagaa
    33361 gttggcaagg aggaatagac ttgcctaaga aagtgaaaaa aaggcatcta ttagactata
    33421 gcatcttgat tccctattta attttatgtg tattgggatt gatcatggta tatagttcta
    33481 cgtcgtatct attattagaa aacggacaaa atccgtccgc atcagtcatt aaccagagta
    33541 ttttttgggt gcttagcttg attgctatcg cactacttta taaaatgaaa acagatgttt
    33601 tgaaaaacca gcgtttgatc atggcagcca tcgcagtttt gacgattttg ctgctgattg
    33661 ttgtgttttt tggtaaggag atcaatgggg cgaaaggttg gctgcaaatt gcaggattct
    33721 cgatccaacc tgccgaatac ctaaaaatca tttctatctg gtacctgtct ctgactttat
    33781 ctaaaagaca aaacagtgta caaaaagatt ttcttgggac tgtgaaacgt ccacttgcaa
    33841 tggttatcgg acttactgca ttagtcgcta ttcttcccga ttttggtaat gcggcagtta
    33901 tctttttgat tattttggtt ctgcttttag ccagcggagt caattatgtg tatactttga
    33961 ttgtaggagt aggaggcttt tgtctaagta cttttacgat ctggctgatc aatatcacaa
    34021 acggaaagat cttacccgga cgtttacagt atatctataa tcgatttgct atttaccaaa
    34081 atcctttctc agacgaatta aataaagggc atcaactagt caacggctac tatgccatgt
    34141 tcaacggagg actatttggc aggggattag gtaacagtat ccagaaaaaa ggatttttac
    34201 aagaagcaca aaccgatttt atttatgcaa tcgtagtgga agaactggga gtgattatgg
    34261 ggattttgat attagcgttg ctattcttta tgattgtgcg cattgtcctt gtaggtatcc
    34321 gttcaaaaga tccgttcaat tcgcttttgt gcattgggat cggcgcaatg tttttgatcc
    34381 aagtatttgt caatcttgga ggaattactg gcgttattcc tttgacaggg atcacgttcc
    34441 catttttaag tcaaggaggc tccagtttgc tgatgctttc gatttgtgtc ggctttgtcc
    34501 tcaacatcag tgcggatgaa aaacgcaaga gcttaggttt ataataaaaa aagatgtagg
    34561 agtggttcga tgaaaaaagt tttagttgct aacaggggtg aaatcgctgt acgtgtattt
    34621 cgtgcttgta cagaattagg aattaaaact gttggaatct atgcagaaga agatgaatat
    34681 tccgtacacc gtttcaaagc ggatgaagca tatttagtag gacaaggaaa aaaaccgatt
    34741 gatgcgtatc tagatattga agggatcatt tctatcgcga aagaatgcgg agctgacgct
    34801 attcatccgg gttacggtct tttgtcggaa aacttgaatt ttgcgcaacg gtgcgaagaa
    34861 gaaggcatca tttttgttgg acccaaactg catcatttag atatttttgg agataaaatc
    34921 aaagcaaaag ctgcagctat cgaagcgggg attgcttcga ttccaggcac agatggacca
    34981 atcgcttcta tagacgatgc cttggagttt gcgaaacaat acggttatcc gattatgatc
    35041 aaggcagctc taggcggcgg cggacgcggc atgcgtgtag ctcacgatga aaagagtgca
    35101 agagagggct acgaacgtgc gaaaagcgaa gcaaaagcag cctttggtag tgatgaagtg
    35161 tatgttgaaa aatacatcgc taatcctaag catatcgaag tacagattct cggggatacg
    35221 catggaaacg tcatccatct ttttgaaaga gattgttctg ttcagcgccg tcaccaaaaa
    35281 gtagtagaag tagcgccttg tgtctctatg aatgaacagc aacgtcaaaa aatctgccag
    35341 gcagctgtcc aattgatgaa atatgtcggg tatgtcaacg caggtacagt agaatttctt
    35401 gttgaaggag atgattttta ctttatcgaa gtcaaccctc gcgtccaagt ggaacatacg
    35461 atcacagaaa tgattacaga tattgatatc gtaacaacgc aactgttgat tgctcaaggt
    35521 ttggatctgc ataaagaaat cggattgcct cagcaagaag gaattaaatt aaatggttca
    35581 gccattcaat gccgaatcac tacagaagac ccgttgaata actttttacc agacacaggg
    35641 aaaatcgata cgtatcgttc acctggtggt tttggcgtac gtctggatgt cggaaatgct
    35701 tacgcgggct atgtagtgac accgtatttt gattcattgc tagtaaaagt atgtacgcat
    35761 ggtgctacct ttgaaacagc cattcagaaa atggaacgtt gcttgaaaga atttagaatc
    35821 cgtggagtga aaacaaacat tccatttatg ctcaatgtca tcacacatcc tgaattccaa
    35881 tcaggaaatg caaaaacaac cttcattgat agtacagcaa cattatttga atttcctcga
    35941 ctacgagacc gcggaaacaa aacgatgaaa tatatcggtg aaattactgt gaatggtttt
    36001 ccaggtatcg aaagtggcga aaaaccattt tatgaagaac cacgtatgcc taaagatcta
    36061 atcacaagaa ctgattacgt aacggctaag aatgtattag atgcgaaggg tgccgatgct
    36121 ttggtcgaat ggatcaaagg acaggaaaat ttgttgttga cggatacgac atttagagac
    36181 gcccatcaaa gtctgctagc aactcgtgtt cggacaaagg atttcaagca gattgcacgt
    36241 ttgactggag aaggtcttcc tgaactcttt tcaagtgaga tgtggggggg agcaacattt
    36301 gatgtggctt accgcttttt gaatgaagat ccttggcaac ggttgagaaa aattcgttct
    36361 ttaatgccta atacgttgct gcaaatgctt ttcagaggtt caaatgccgt tgggtattct
    36421 aattatcctg acaatgtatt ggtggaattt gtcaaagaag cagcagcgca aggaatcgat
    36481 gtatttcgaa tctttgatag tttgaactgg actccacaaa tggaaaaaag tatccaagct
    36541 gtacgggata ctggtaaaat cgcagaggca gctatttgct atactggcga tatcaacgat
    36601 ccaagtcggg caaaatacaa tgttcagtat tataaagaca tggcaaagga actagaacaa
    36661 ctgggtgcgc atatcattgc aatcaaagat atggctgggc tgcttaaacc gcaggcagct
    36721 tatcgtttga ttagtgaatt gaaagaaacg acagatctgc caatccatct gcatactcat
    36781 gataccagcg ggaatggaat catcacttat tctgctgctt caaaagcagg agtagacatc
    36841 gttgacgtgg caatgagtgc aatgagtggg aatactagtc agcctagcat gagcagcttg
    36901 tattatgcac tggtcaatgg tccacggctg ccagaaatca cgattgaaaa tgcacagaaa
    36961 ttaaaccatt attgggaaga tgtgcgcatg tattacaaac cgtttgaaaa cggcttgaat
    37021 gctcctgaaa cagaagtata tatgcatgaa atgccaggag gacagtattc gaatctacag
    37081 caacaggcaa aagctgtcgg attaggtcat cgctgggatg aaatcaaaca aatgtatcat
    37141 actgtcaact tgatgtttgg cgatatcgtt aaagtaactc catcatctaa agtagttgga
    37201 gatatggcac tatttatggt ccaaaatgat cttacagaag aagatattta tgaaaaaggc
    37261 gaaacactaa gtttccctga atctgttgtg actttcttcc aaggagaact agggcaaccc
    37321 gttggcggat ttcctaaaaa attgcaaaag attattctta aaggcagacc tgcattgaat
    37381 gaacgtccag gtcttttggc tgaatcagtc gacttcaacg aagtaaaaaa agaattggca
    37441 gaaaaaattg gctatgaacc aaaacaagac gaagtattaa gctatttgat gtatccgcaa
    37501 gtctttttgg actatcaaaa agcatataat caatttggcg atgttacatt actggacaca
    37561 ccaacatttt tccaaggtat acgtttgggt gaaacaatca atgtacaaat cgaacgcgga
    37621 aaaacgctta tcattcgttt agatgaaatc ggagaacccg atatcgaagg gaatcgcgta
    37681 ctgttcttca atttgaatgg acaaagacgt gaaatcacta tcaaagataa ttcgatcatc
    37741 agtacggtcc aaacccgatt gaaagctgaa ccgacaaacc gagaacaaat tggagcaacg
    37801 atgtctggtt ctgttttgga tgtattagtg aaaaaaggcg ataacgttaa aaaaggtgat
    37861 acgttgatga ttactgaagc gatgaaaatg gaaacggcca tcgaagcacg ttttgacgga
    37921 gaagtcgcac atgtatatgt gtcttcagga gacactattt cgtctggtga ccttttgatt
    37981 gaagtgactg agaaataata agcgaaaggt ggggaaacat gaaaagactg ggtttgtttt
    38041 ggctgattct gctattagtt attgtggcat tctacatgga accagtcttg tttccgccaa
    38101 aacttgaagt gaaggaaaac tctgatcaac aaatatcaaa ccaaatgaca acgtggaaat
    38161 accaggagct taaagcaact ggtttttcta cttatatcgg aaaaccgatc gatcagctgg
    38221 aaaaggattt tggccaagcc tatgatcgat taactagcgg atttggtttt gaaacaagat
    38281 attatgaaaa taaagctagt catctcacat ttgaagcgaa catccaagac agcagagtca
    38341 caactgttaa agtactgcaa acagggcctg ctgatatcgc gccgttttat ttagggatga
    38401 cgatgcaaga tcttacgaaa atcactacta tctatactaa tttcactttt gagtaccatg
    38461 atacagaagt tggaatcgaa ctaatggaag aggatatgaa ttatcgtccg ctaattgctt
    38521 ttgataacga cacttttgct attttatttt ttgatcaaac aacaaacggc ctattttcag
    38581 ttgtgtattt agataaagat agtcttttga aactattgcc atatcaagtg tttggtgaag
    38641 gccttccaca ttatcaagca gataaatcgg ctgattggga atcaatcaat cgcgttaaag
    38701 aacgaaaaag tacgacttta ttaaatatgc ttagaagaga agacgaactt cccatataca
    38761 atcaaacact tgcctttcaa aaccacagtc agctgctact acatgatttt ttgacaaggc
    38821 ctgaggaaat attgtcagag gaacgtatgg ctgattggca aaaatcgcta ggcagtgctc
    38881 aaacgacagt gaaattctca ctgacgaatg atgaattgga gaagttaatc agtaaacaaa
    38941 aattagaaaa tactagtggg ctatttattc atccggcgat tgacgctact ttttcgtttt
    39001 tatattggta cagcgatcct tacaaccatg accgtttcat ggacccggga acggattctg
    39061 taggcattgc tttttctaaa gaaaatatgt tagtcttatt gcaagaagaa aacggagaaa
    39121 gtagtgatag cagtgatcgt taacgaagag ctgtttcaac tggaggatca atgcctccaa
    39181 gtcgctgaaa tgataaaaaa gagtaaaacg atggcttctt atcttgaaca taaacagtca
    39241 atggaagaat ctgcaaaagt ttgccagttg aaagaagcgt tcttgtctaa gaaagaagca
    39301 tttgaaaatg tagcggcata tggtgagtat gcacctgatt atcgtgaaaa aaaacgagct
    39361 gttcgaaaag caaaaagaca gcttgatatg gatgagcatg ttgcagcttt ccgatatagt
    39421 gaaacacagc tgcaaagtct gttggatcaa attgtccaag tacttgccga agaagtttct
    39481 aatgaaatca aagtagatgc aggtagcccg ttttttgaaa cgaaaaaaca ctttggatgc
    39541 ggaggtaatt gtcatgcaat tagacaatag tgaatttgaa ataacaaaac gacgcgggct
    39601 gatcgtatgg gtctacagct taaaacaatt aaagaatctg aaaaagttcg gcttgttgca
    39661 ttatgtctca agaagaatga aatatgtcgt gctttactta aatgaagaga cattggaaga
    39721 aacagaagaa cgaatccgta aattacattt tgttcgaaac gtagaacgtt cttaccgacc
    39781 ggatatcgaa atgaattttg ccgaaaaaat aggaaacaaa acagtattaa aagacgaagg
    39841 tttcgaaatt gaagagctaa atacagaaat ccgattagct gaacatcttt aaaaatctct
    39901 tatgagcagt ttttaaataa aaaataactt ggataacgat cgatttttga tcattgtcca
    39961 agtatttttt tggtatacta gtaccagtac catttctaag gagtgagtag atgcggataa
    40021 tatcaggaaa ttatggcggg cgccgtttaa aaagtttagc aggggcgaac accagaccaa
    40081 ctacagataa agtaaaagaa tccatattca atatgattgg accatatttt gatggagaga
    40141 cagtattgga tctgtttgca ggaagcggtg gtttagctat cgaagcagta tctagaggct
    40201 gcagtcatgc ggtatgcgta gacaaaaatt accaagcgct aaaaatcatc aaagaaaaca
    40261 tcgaaattac gaaagaacca gagaaattta ccacaataaa acttgatgcg gacaaagcaa
    40321 tcgaacggct agcagcggag aaacaacaat tcgactactt gtttcttgat ccgccatatg
    40381 caaaacaaaa aataatcgat caaatccata aaatggaaga actgggactt ttttctaaaa
    40441 ccgcagttat cgtatgcgaa acggataaaa cagtcgaatt gccagaaact gtggctggat
    40501 tccatcaaat aagaaaacag atttatggca taacggccgt aactatctat agaaaagagg
    40561 gaaatcaatg aaacgtgcat tattcccagg aagttttgat ccttttacaa aaggtcactt
    40621 agatacggtg gaacgtgcgg ctaaattatt cgatgaggta gtaattggtg tttttatcaa
    40681 tacttcaaag aaaagtttgt ttcccccaga agaaagaatg acattgatca caaaagctgt
    40741 ttctcatctt cctaatgtaa aagtcatgca tcaagaaaat caattgacgg tagaaacagc
    40801 aaaagagatt ggtgcagatg cgttgatcag aggcatacga agtatcaaag actttgaata
    40861 tgaacgagag attgctcaga tgaatcatca tctatatgat gaattggaaa ctgtcttctt
    40921 attagcaaaa ccagaatata gtcacgtgag ttccagtatt ttaaaagaag tactgcactt
    40981 tggcggagat gtgagcagct acttaccgcc agtgatcaac gaagctttag ctggaaagcg
    41041 tgaatcaaat gaaagctaaa caatggttga aaacagtact gattatcata tttggaatgt
    41101 tgatcattgg atttgtagta gttcccttgc cgtattatgt agaatcaccg ggagccacga
    41161 tcgatctgaa agaactaatt acggtcaatg ataaggaaga taaaggttct gggtctttct
    41221 ctcttacctc tgttggtatc aggcaagcta caggtttctt agctttaaaa gctaaaatga
    41281 ccccttttga agaattgatc agtgaagaag aattgactgg tggggcgaca aatgaagaat
    41341 ataatcaaat gcaacagtat tatatggatt cttcccaaaa tgcagcaatc gaacaagcgt
    41401 taaaacttgc agacaagcct tataaaatgg aattcaaagg cgtatatgtc atgagtgtag
    41461 agaaaacatc gaatttcttt ggcaagcttt cagttggaga tacagtaaca aaagtagacg
    41521 ggaaaagctt tcaaagtaca gaagcattta tggattatgt aaaaagccaa aaagttggac
    41581 aaacaatcga aatcagttat ttgcataatg gtgaagaaaa aacagcttct ggtgatctga
    41641 tcgagttacc aacagataaa aaggcaggaa taggtatcac gcttactgac cataccgaga
    41701 tcgaatcaga tacagatgtt cgtattaatt ctggctctat cggtgggcca tcagcgggat
    41761 tgatgttcac tttagaaatc tatgaacaag tcactggtaa aaacttgcga catggtaagc
    41821 aaattgcagg aactggaacg atcaacagtg aaggagaagt tggccgaatc ggaggaatcg
    41881 ataaaaaagt ggcaagtgcg gataaagctg gcgtagagat tttctttgca ccagatgata
    41941 cgatttcaga cgatgttaag aaagaatatc ctgaaataaa aaccaactac gaagaagcaa
    42001 aagctgccgc taaaaaattg aattcctcaa tgaaaatcgt accagtaaaa acagtacaag
    42061 aagcgcttga ctatctagag aaaatgaaat gaaactaaat aattaaagag gggttgtgac
    42121 acga
//
LOCUS       DADVXB010000008        37213 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.008, whole genome shotgun sequence.
ACCESSION   DADVXB010000008 DADVXB010000000
VERSION     DADVXB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.008"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1061)
                     /locus_tag="KB902_000316"
     CDS             complement(<1..1061)
                     /locus_tag="KB902_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6807171.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITE"
     gene            complement(1206..4004)
                     /gene="ileS"
                     /locus_tag="KB902_000317"
     CDS             complement(1206..4004)
                     /gene="ileS"
                     /locus_tag="KB902_000317"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBB6807172.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(4266..4973)
                     /locus_tag="KB902_000318"
     CDS             complement(4266..4973)
                     /locus_tag="KB902_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBB6807173.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            complement(4994..5776)
                     /locus_tag="KB902_000319"
     CDS             complement(4994..5776)
                     /locus_tag="KB902_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBB6807174.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            complement(5825..6112)
                     /locus_tag="KB902_000320"
     CDS             complement(5825..6112)
                     /locus_tag="KB902_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBB6807175.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            complement(6127..6726)
                     /locus_tag="KB902_000321"
     CDS             complement(6127..6726)
                     /locus_tag="KB902_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBB6807176.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            complement(6740..7417)
                     /locus_tag="KB902_000322"
     CDS             complement(6740..7417)
                     /locus_tag="KB902_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBB6807177.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            complement(7434..8675)
                     /gene="ftsZ"
                     /locus_tag="KB902_000323"
     CDS             complement(7434..8675)
                     /gene="ftsZ"
                     /locus_tag="KB902_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBB6807178.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            complement(8698..10023)
                     /gene="ftsA"
                     /locus_tag="KB902_000324"
     CDS             complement(8698..10023)
                     /gene="ftsA"
                     /locus_tag="KB902_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBB6807179.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            complement(10179..11399)
                     /locus_tag="KB902_000325"
     CDS             complement(10179..11399)
                     /locus_tag="KB902_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBB6807180.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            complement(11414..12502)
                     /gene="murG"
                     /locus_tag="KB902_000326"
     CDS             complement(11414..12502)
                     /gene="murG"
                     /locus_tag="KB902_000326"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBB6807181.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            complement(12528..13889)
                     /locus_tag="KB902_000327"
     CDS             complement(12528..13889)
                     /locus_tag="KB902_000327"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBB6807182.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            complement(13903..14865)
                     /locus_tag="KB902_000328"
     CDS             complement(13903..14865)
                     /locus_tag="KB902_000328"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBB6807183.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            complement(14891..17083)
                     /locus_tag="KB902_000329"
     CDS             complement(14891..17083)
                     /locus_tag="KB902_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6807184.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWST
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            complement(17084..17485)
                     /gene="ftsL"
                     /locus_tag="KB902_000330"
     CDS             complement(17084..17485)
                     /gene="ftsL"
                     /locus_tag="KB902_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6807185.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            complement(17490..18449)
                     /gene="rsmH"
                     /locus_tag="KB902_000331"
     CDS             complement(17490..18449)
                     /gene="rsmH"
                     /locus_tag="KB902_000331"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBB6807186.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            complement(18470..18901)
                     /gene="mraZ"
                     /locus_tag="KB902_000332"
     CDS             complement(18470..18901)
                     /gene="mraZ"
                     /locus_tag="KB902_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBB6807187.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            complement(19071..19439)
                     /locus_tag="KB902_000333"
     CDS             complement(19071..19439)
                     /locus_tag="KB902_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBB6807188.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            19610..20566
                     /locus_tag="KB902_000334"
     CDS             19610..20566
                     /locus_tag="KB902_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6807189.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            20639..20755
                     /locus_tag="KB902_000335"
     CDS             20639..20755
                     /locus_tag="KB902_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBB6807190.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(20810..22492)
                     /gene="recN"
                     /locus_tag="KB902_000336"
     CDS             complement(20810..22492)
                     /gene="recN"
                     /locus_tag="KB902_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBB6807191.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22510..22959)
                     /locus_tag="KB902_000337"
     CDS             complement(22510..22959)
                     /locus_tag="KB902_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6807192.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(23066..23884)
                     /locus_tag="KB902_000338"
     CDS             complement(23066..23884)
                     /locus_tag="KB902_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBB6807193.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(23893..24783)
                     /locus_tag="KB902_000339"
     CDS             complement(23893..24783)
                     /locus_tag="KB902_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6807194.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(24785..25009)
                     /locus_tag="KB902_000340"
     CDS             complement(24785..25009)
                     /locus_tag="KB902_000340"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBB6807195.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(25014..26351)
                     /locus_tag="KB902_000341"
     CDS             complement(25014..26351)
                     /locus_tag="KB902_000341"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBB6807196.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(26352..27206)
                     /locus_tag="KB902_000342"
     CDS             complement(26352..27206)
                     /locus_tag="KB902_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBB6807197.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADTLVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(27303..27752)
                     /gene="nusB"
                     /locus_tag="KB902_000343"
     CDS             complement(27303..27752)
                     /gene="nusB"
                     /locus_tag="KB902_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBB6807198.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(27745..28170)
                     /locus_tag="KB902_000344"
     CDS             complement(27745..28170)
                     /locus_tag="KB902_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6807199.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(28416..29480)
                     /locus_tag="KB902_000345"
     CDS             complement(28416..29480)
                     /locus_tag="KB902_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6807200.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(29652..29897)
                     /locus_tag="KB902_000346"
     CDS             complement(29652..29897)
                     /locus_tag="KB902_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6807201.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(30036..30410)
                     /locus_tag="KB902_000347"
     CDS             complement(30036..30410)
                     /locus_tag="KB902_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBB6807202.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(30493..31407)
                     /locus_tag="KB902_000348"
     CDS             complement(30493..31407)
                     /locus_tag="KB902_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBB6807203.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(31428..32231)
                     /locus_tag="KB902_000349"
     CDS             complement(31428..32231)
                     /locus_tag="KB902_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBB6807204.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(32264..33253)
                     /gene="manX"
                     /locus_tag="KB902_000350"
     CDS             complement(32264..33253)
                     /gene="manX"
                     /locus_tag="KB902_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBB6807205.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(33356..33847)
                     /locus_tag="KB902_000351"
     CDS             complement(33356..33847)
                     /locus_tag="KB902_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6807206.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(34038..36845)
                     /locus_tag="KB902_000352"
     CDS             complement(34038..36845)
                     /locus_tag="KB902_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6807207.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
BASE COUNT        10251 a         8176 c         6210 g        12576 t
ORIGIN      
        1 tcttcggtta ttctttcttc ccaggatttt ggtcttaagg cctcattcag attgataaac
       61 agctttttta ctcgtttctg atactccttc atgacctttt tcattaatgt tttgattcta
      121 cgactataga ttccatagcg acgaatcgtt ttgaaattct tattttgaat atggcgaatc
      181 agtgcagcta tgaattcgtc tatactcatg gtcatcgtct ctttagtatt cgttcgtttg
      241 tccatgtagt tgaacatgac agtgtcgcca tcatacatta agattcggct taatgcgatc
      301 gggccacgct tcatataacg actgatgtat tggagtagtg actttagatt tgtcctgctc
      361 cttttaggag catttacgta aaacccttct ccattgttct tgtacgcagc ttgtaatctt
      421 gattgaactc tttgcttgtc ccactcacct aacgttcgtc taattagttt caatacagca
      481 tttttccagt attttcttaa catagaaaaa ggtaaataat cgtattcttc ccaacttcca
      541 tctcttgtta agccacccat agtaacaacc atatgaacat gcggattaaa ttctagtttt
      601 gatccaaagg tgtggattgt agctactata cctgccttca cctttctttt ctcaaaatag
      661 gcaagaataa tttttgcggc ttcatccatt agtcctttca gtaaggaatc tcgatagttt
      721 tccatcataa agatttcccg taacccctca tcgatcgtaa agattacgtg ccgatgtgtc
      781 actttaaaca tatcattcgc cacaaccgct gaccaccttt ggctttcacc tgttgcacac
      841 gttggacaga actttccacg acatttcaag ggaacaaact ttgtttgatg acatccctcg
      901 cagacaaaca gtcggtatcc tttttgaata tctccacaat atctaaactt gtttacttcc
      961 cgtttgacga ctagccgaat ctttcgcccg tatttctcaa caaagttatc ccaattatgg
     1021 tgttcgtcaa aaaagattgc ttcgagaata ttcgctttca tagtaatatt ttacttgttc
     1081 aaaaacaaaa tgaaaagggc taaaagactg gtagtgcagc ctttttagcc cttaactttt
     1141 tatactttct ttactgttaa caaaaggggg tgtgacaaag aacatgtcac accccctttt
     1201 cccttttact tttcttcgaa tccttcagct acagcttcag gatagaagtc ttcaacgatt
     1261 tttgcacaac gaccgcatag atgaggaagt ttttcatcta ctcctacatc tttacgaact
     1321 tggcgacagc gatcgcaagt ttccccgtct gctttttcca ctgtaatagc aacatcatca
     1381 aataccatag cgttatctgg cacttgttca tctgctgcca taacttcaaa gtagtctggt
     1441 gaaacgatca ataattgtgc aatatctgca tccaaagctt ttaacatttc acgaacttgt
     1501 tgttttggat aaacagttag ttttgcttcc aaagatttac caatcaattt gctgtttctt
     1561 gcttcttcca atgcttttaa gacattatca cggaagtcca tgaaagcagt ccaggtatcc
     1621 atcaattctt cttggtttgc aaactcttca taaccaggaa actcgcttaa ctgaacgtac
     1681 tcctcttctt ctttcaggaa tgaccagatt tcttctgctg tatgcggaat gataggagtc
     1741 aataattttg tcaaagctac agctgtttga tagaaaacag tttgcatgca acgacgttga
     1801 taatcatctt ctgcttcaat ataaactaca tctttagcaa aatccaggta gaatgacgat
     1861 agatcaaccg tcaagaagtt cataactgta cggtaaatat gcatgaagtt atatttgtcg
     1921 tacccttctt ctcggatttc tttgattact tggttcaatc gaacggtcat atatttgtct
     1981 acagaacgta aatcattgta cgaaacagta tcttttttag gatcgaaatc ttctgtattc
     2041 gctaataaga aacgcatcgt atttctgatt ttacgatata cttctgccac ttgacttaag
     2101 atatccatag aaacacgaac atctgcttca taatctacac tagataccca taagcgaagg
     2161 atatctgcac caaattgttt gatcactttt tctggtgcaa tgatgtttcc taaagattta
     2221 ctcatcttac ggccttcacc atctaaagca aatccttgag aaataactga tttgtatggt
     2281 gctacaccat tgatagccac actagtcgtg atacttgagt tgaaccagcc acgatattgg
     2341 tctgatcctt ctaaatacat atctgctggg aatgataatt ctggtcgctg acgtaaaaca
     2401 gcttcatgag aagaaccaga atcaaaccag acatccatga tatctttttc ttttgtaaat
     2461 tcgccattag gagaacctgg gtgggtaaat ccttcaggaa gaagttcttt cgcttctttt
     2521 tcaaaccaga taattgatcc atgttcagca aataattttg ccacatgttc gattgtttct
     2581 ggtgtgatga ttgcttctcc attttcagca tagaaaatcg gaagtggtac tccccatgca
     2641 cgctgacggg aaattaccca atcgccgcgg tcacggatca tattatacaa acgtgtttta
     2701 ccccatggga taacccactc tactttttct acttcatcca aaatattctg acggaattta
     2761 tcgatagatg caaaccattg tggagttgcc cgatagatca caggcttttt cgtccgccaa
     2821 tcgtgaggat aactatgagt aaagaaatct agcttcagca aagctccttt ttcttttaat
     2881 agatcagtga tcataggatt tgctttgtca taaaagatac cttcaaatcc aggtgcttct
     2941 tctgtaaaca atccttttga gtctacaggt gacactacag atagtttata tttgctacca
     3001 gcgatatagt catcttcccc atgtcctgga gcagtatgga ctaatccagt accagcgtct
     3061 aaagtaacat gatcgcctaa aatcacaagt gattcacgtt catagaatgg atgacttgca
     3121 gtcatatatt ccatttcttg tccagcaaat tcttttagaa ctgttacatt ttcccaaccg
     3181 atttctgatt ggactgtttc tagcaaatct ttcgctacga caaacttacg gccatcggct
     3241 tccaccaata catacgtaaa ttttggattt acagcaatac cttggtttgc tggcaatgtc
     3301 catggtgttg tcgtccaaat gacaaaagct gtatcttcat caagaatatc tttgccgtct
     3361 ttgacattga aagctacaaa aatagatgga gattttacat ctttatattc aatttcagct
     3421 tccgctaaag aagactcact tgacggagac cagtaaattg gtttcaatcc tttgtaaata
     3481 tagccttttt cagccatttt accaaatacg cgtacttgtg cagcttcata agaaggatct
     3541 aatgtaacat aaggatgttc ccaatctcct gcaactccta ggcgtttgaa atctgctcgt
     3601 tgcttatcta cttgggaaag tgcatattca cgacattttt ccaagtattc tgccatggac
     3661 atttctttac gtttcacgcc tttattagcc aatacttgtt caatcggcaa tccatgtgta
     3721 tcccatcctg gaacatatgg tgcacgatag ccagacattg attttgaacg aatgataatg
     3781 tctttactga ttttattcaa tgaatgtcct aaatggatat taccattggc atatggaggt
     3841 ccatcatgaa gaacaaagct aggttttcct tcgttcaact cttgtctttt ttggtagatt
     3901 cgattttctt cccattcttt ttgccactcg ccttctcggt ttggcaaatt accacgcata
     3961 gggaattttg tttttcctaa ttgcaaggtt tctttcattt tcattcaacc atacactcct
     4021 ttatttgttt tccggacaca aaaaagcatg ttcagccgca agggacgaac atgccgtggt
     4081 accacccaaa tttagttgca tctatctagt gcaaactctc tgtgaccaat aacgaggtca
     4141 gccgctgctt cttactctaa tttcggaaaa gcaggtctca agtagaggat ctttcaccat
     4201 gcagtgtctt accgaacttc cactctcatc ggctcgcttt aagaataaca aagtgctttt
     4261 ctgttctact cgttttcatt ttcaccaggc acgatcgaga tatcaatagc ctgtgtatca
     4321 aatgccgtca taggtgcttc tatgactcct gtgtctgagt ttacatcagt atcattttca
     4381 ttgtcaagct gttttgctaa aacttctttg atcacttcat ggctgtcagt cacgtagctg
     4441 gagaatggtt gtaaaatttc atcccattcc ggacttttca cttgttctaa ttgagactca
     4501 agcatcaagc tgatacgttg atggaatact cgtgtttttt tcttaagatc ttcagtttct
     4561 gtcgcaagct gtcttgcttt ttctgttgca tctgtcaaga tttttcttgc tttttcttct
     4621 gcatcagttg ttaattgatg tgcacgtttt tcagcgttcg caactaactc atctgctttg
     4681 ttttgtgcag aagtaacgat cacttcggat tccttgcttg cacttgtttt tactttatca
     4741 gccgtatctt gagctacgat gattgattgg ttcaaagcat cttttaattc attgaagtac
     4801 tcaagttttt cttcagaatg tttgactgct ttttctaatt ctcgatttct ttgagtcaat
     4861 tcctcatagt cacgaacaac taaatctaag aaatcatcta cttcgtcttg attatatccc
     4921 cgcatttttg tcgggaatgt cttattttgg atatctaatg gagttaaagc catgagtaaa
     4981 ccaccttttt attttattta cgtaatacac cgaacagtac cctgtacttt tcttttttcg
     5041 tcttcccctc aagttcttgg atctggactc tgccataacc tctgactgaa ataatatcta
     5101 atagttcaag tacaaaatca ggtcttgtat tttctgtcca gttcactttt actttaccag
     5161 cttcgatcag ctgcttggac cgctgtctgg aaatattata aatctcagag atcacactgt
     5221 ctagtcgcat ggaactaact gttcctcttt cttgtgtcca gctatctttc ggcataatca
     5281 tttctgtgta tttgattggt tccaagcgta cagcaacctt tccaatcttt gttacttgtg
     5341 cagcaacaaa atgatccacc tcatttgcaa taaatacttg ccagcgatca ccgtccgaga
     5401 tgatatcgcc aaagtaagag cgtttgatcc ccgttcccac taaagttcca aggattttcc
     5461 catgacttag gctggcaaat ttgctaggat aatggatttc atacaatgct gtttcaaaat
     5521 cttcctctac aggttcgtaa taatcgggga aaatcaaaca tctttttctt tctgcctgtt
     5581 catatccgcc ataaaacatg aaacgcaaat cactgctttg tcgaatcagt gtttctaaaa
     5641 tataggattg tcttgggtca agaaattcgg tcagataggg tgcatattgt ccttgaacct
     5701 gttcaatcca atcgcctacc gaatcgataa atgtacgttc atctgcccga aagtgctggt
     5761 atacatttgc atccaaaatt ttcccctcct atctattctg agaataaaga ttttgttgct
     5821 tcaatcaata aactaaatgg acagttatcc atataacgat ctgtgctaaa ccttgtacgg
     5881 ctaagttcaa gatcaggatt gcccctaaaa ttgtgaaatc caagggtcca atcctcaaag
     5941 gcagacgatc gaacaaactg atatacggtt cgcagatctt agctaataat cgtcctagcc
     6001 ctgattgata cccgcctgga aaccaagaga gcaatgcata taccatcaag ataatgctat
     6061 agaaataggc tgcccgttga agtaaatgaa gtaatagtgc aatagtataa atcgtagttc
     6121 ctcctcttac agatcaaaca aattcgcatc tgcaaaagat tgagcggttg aactgtcaat
     6181 ctccatccca gtcggtgtac aaagaaaaat ctcatctcca acacgtttga tatctccatc
     6241 tagtgcataa actgttcctg ttagaaaatc aacgattctt ctcgcttgtt tttcttctac
     6301 taaatgaaaa ttcactaagg ttgcttctcc agcaatgatt cgtttagcaa tcgccatagc
     6361 ttcagaataa gctcttggtt ccattacagt gatttttcca gcaagatttg ctttaggttg
     6421 tgtagaggtt cttgaagctg ttctttcttt cgctacagtt tttgtaggtg attgatgtag
     6481 ttcaattact tttttctttt cagccggctg aatactttca tgcgttacag gacgtgaagt
     6541 cgccgttttt tgtttttcat gagtattcgc agcagataca gaatgagttg attgattctg
     6601 tgttgtattt tttttagttg gctgtacagc cttttttgtt gtttcaggat aatcttggta
     6661 ttcgtactct tcctcatcag ctaatccgaa aaaattagca attgctcctc tgtttaaaag
     6721 cggcattttt gttcctcctt tattcgtctt tgaatagcgc tgttcctaca cggataaatg
     6781 ttgcaccttc ttcaatcgca atttgaaagt cttgactcat ccccatactt aattcactac
     6841 atggtgcatg ggcataacct tttgcttgaa caagatcacg caattctttc agcgtaccaa
     6901 acactttatg gatttgctca tcagaagctt ctttaggcgc catagtcatc aacccaacaa
     6961 ccttgatttt tgtgcaggca gctaaagatt ccacaaacgg taaaagctca tctggtgaaa
     7021 ttccatgttt tgattcctca ccagaaacat ttacttcaat aaaacaggat aattctttct
     7081 ctaaccgctt ctggatttct tctgctaatc ttaaactgtc caacgcatga aagtaatcaa
     7141 tttcatttac aatcaatttt acctttctgc gctgtaaatt accaattaaa tgccacttta
     7201 tttcaggaaa atcaaataaa tcttgtttct tttctaataa tttatctact cggttttctg
     7261 cacaattcat aacgccagct ctaaccaatt cttcagcttg agcggattca acagattttg
     7321 ttacagctac taatgtaact tctttcggat cacgatgaac aagagcacac gaatcctgaa
     7381 tttcttgctt gattttctgc aagttgtcag caatcatgtg ctcttcctct cctttatttt
     7441 ttacgacgga aaaacggtgg cgtatttaat tcatcatcgc catgagattt tgtttcttcg
     7501 cggttgaatg tatcaaattc ttttttttcg atattgtcaa aattggaatc atcaactcta
     7561 ggacgaacat tttgttcacg tctgatatcc caatcgccaa aactgttttc ttcttctgaa
     7621 gaagttggtt tagcttgatc catatctaat acagtctttt gagcaggtga ttgcatttgt
     7681 gcttgtctag ctggtcggct agacttgcgt tccttttttg attcatcgat acctgttgcg
     7741 atgaccgtca cacggatttc atcgcccatt tcttcattga tagatgtacc tagaatgata
     7801 tttacatcgc cagttgctgc atttgctacg atatctgaag catcttgtgc ttcgaacaat
     7861 gtcatatcca aaccgcctgt gatgttaaga agtacttgtt cagctccatc aatagatgtt
     7921 tcaagcaatg gagaggagat tgcttttttc gttgcttcta ctacgcgatc ttctccacta
     7981 gccacaccga tccccatcaa tgctgtacct tggttttcca tcactgtttt cacgtcagca
     8041 aagtcaaggt taacgtaacc tggcgctgtg atcaaatcag agataccttg tacaccttgt
     8101 cgtaaaacat tatctgcttc acggaaagct tcaagcatcg gtgtcttttt atctacaact
     8161 tctaataaac ggttatttga gataattaat aatgtatcca cattttcttt caaacgagcg
     8221 ataccttctg cagcaaaacg gccacgtttc ggtccttcaa aagtgaatgg acgtgtcacg
     8281 acaccaacag tcaatgcgcc caattctttc gcgatacctg caacgattgg tgcagcacct
     8341 gtaccggttc ctccacccat tcctgcagtg atgaaaatca tatctgcacc gtctaaagct
     8401 tcgcgtaagg attgttcact ttcttctgcc gctttttgtc caacttctgg ctgagaacca
     8461 gcacctaaac cacgagtata tttggggcct aattggataa ctgtttcagc ttttgaattt
     8521 tttaatgctt gcacgtctgt gttggctgta atgaattcaa cacctttaac gttttcttca
     8581 atcattcggt ttacagcatt tccaccgcca ccaccgactc cgatgacttt gattactgcg
     8641 ccgtcattga tattattatc aattgagaat tccatatctt attcctccca ggatgaatta
     8701 atcaaaaata tttgtaaaga aacccttgat tttatttttt acattttctc cggactcttt
     8761 tggttccggc tcatcgtaga ttgtttcttc aggtgcttca tagctctcat atgtgtttgt
     8821 tgtttcttgt tcaactacca tttgacgagc tgctgaggtt tcacccgtaa cagcaatttt
     8881 tgccaattga tacacttcac tcaagtttgc tgaataatcc acgatactta ttacatttgt
     8941 aaataccggg tttctcagcc ccatgtgatt tggaacatac aattttacat ttacgccgaa
     9001 gatttcttgt gccaagtcca caacaccagg aagactagca gctccgcctg tcaatacgac
     9061 gccacctggc aactctaatg cttcgatttg gtccaatgca tcttttgctt tgttgaaaat
     9121 ctgttccatt cgagctgaaa taatttctga caagtagcgt tcatcgactt tcactggttc
     9181 tgactgacca atcacatcta ctggaaattc ttcatctggt gatgtccgtt ctgggtatgc
     9241 atccccgtag tttattttca acgcttctgc attgttaaat gacgtattta atacaataga
     9301 gatatcttta gtgacaaatt cgccaccttc ttggtcaaga ttggtaaact tcaattgctt
     9361 atcatgcata acagccgttg ttgtttggcc gccacccata tcaatgacga tcgtaccaaa
     9421 atctttttct ccgtcagaaa gaattgattc agtcagcgct aaaggagtaa tcaccatttc
     9481 gttgacgatt aatccggcat tttccacgca tttacgtatg ttatggatga tcgttttagg
     9541 tcctgtaaac aacagaccgt acatttctaa tcttacgccg atcattccac gaggatcttt
     9601 gattccctcg aacccatcga cagtaaaatc ttgtggcaat attgacacga tttgacgttc
     9661 aggaggtatt gaacgaacaa gggcagctga agccacattt ctgacatctt catcggtgat
     9721 ttcctttgaa tctccgttaa ctgcaatcat tccctggcaa ttttctactt caagcatgtt
     9781 tgctggcaaa ccgacactta cgcctttgat ctggatacct gctttttctt ctgcttgtcg
     9841 tactgctcgt tgtatcgctt ggaccgtttt atcgatatca acgataatgc ctcggttaat
     9901 cccttctgat tttgcgtttc ctactccaat aatattcatt tggctgtcga tatattcagc
     9961 cacgacaact ttaacagatg tcgttccaat atcaaggcct acatacattc ctgtttttgc
    10021 catgaatggg attccctcct acttactatt ccatatacaa gcgaacaact agcgtccgtt
    10081 ttaaaatata cttattaata gatatattca ctgcttccaa ttctaccata aattactggt
    10141 ttttagaaag tacattctta ctttttaaag ttgttttatc aattttcatt taaacttgac
    10201 ggagttgtac ttggattatc ttctatttga cttgtttcac ttgaatcatt tgaatcagat
    10261 gatccgtttg tgctagacga tccaggtgtt tgtgcttttt gcgtttctgc ctcttcactt
    10321 gattcgtttg tttgatccgc attttcttca ctttcagttg tttcttccga ttggcccgat
    10381 tcttccgttt cttgagtgct accgtaagga tgcgagaaga taccaacttc catgtcgatc
    10441 acaccttttt catccatatc tttggctact tgcgaataat atttcatttg gttcgcaaga
    10501 ttattgatat ttacaataac ttgattgccg tcattcatat tcaattggat cagattttta
    10561 ttgcttgctc ttggcgtgta cttgatttca gaaattgctt tttgtaattc tgatgataac
    10621 tgattgtatt gctttgttaa ttctttgatt tttgcagagt ctttgaactc ttccaagata
    10681 gggagatttt ttgtaggatt tgctactttt tcatctaata ctgttccatt ttcaatcact
    10741 gggtagtatt gattgttttt tgcgatcaaa gcaatctctt tatattctgt tacatccaaa
    10801 tcgaattcat tcatcccttt gaaatgtata tttgctgttt cgattcttgg ctgtgctttt
    10861 ttaaggcgat cgatataagt agatcgatga aaatactgtc cccaaacatt ttctcctaat
    10921 gacaattttg tatcagagat gatttcttgg ctgttgactg tcttattgcc tgatactgca
    10981 actgcttgta atttgctata aggagaaaca taatagatca aaaaaatcag cggtataccc
    11041 aatacagtga tgatcaaagc taaccgacga aatagtactt tgtgccgttg actttttaaa
    11101 ttgggcagcc ggttcaaaaa agaaccgtta tatggtccac cgtttttctt ttgcttgatc
    11161 tcttcaaaaa attcgatttt tttctcggac tggctttctt cttgctgttc ctcttgaacc
    11221 gttttttctt cttcagaatc tgaaaggggt gtatctaatg ttatgtcttc tttttttggc
    11281 tcttggtttt tcatctcttg ttctgccaga tattttcggt tagccttttg ccaaggagtc
    11341 aaattgtttt catcagaaga cggatgagac aatttttttg gttctttttt cttactcact
    11401 aagaccaccg cctttatttt ttgattattt gttttactaa gtcataaaga cgttttgaag
    11461 catcagggat tccttgttct ttagaagctc ggcacatttg cttttgcaat tcttcatcac
    11521 ccatgatttc gttgactgtc tgacttagtg attcacctgt tagttcatta tctgcaatca
    11581 tttttgctgc tcctgcgtga acaagactca ttgcattttt agtctgatga tcattcgtaa
    11641 catatgggct gggaaccaac actgccggta accccagagc tgtgaattct gcgatcgaag
    11701 ttgcaccagc acgccccacc agcagatcac tggaagccat gacctctgcc atatttttga
    11761 tataaggctg gacactaata ttttgtattt caggatttat tttatttagg atctcttcat
    11821 aatatctatc tcctgaagca tacaaaactt ggtaagaaga aggaatatat tcacttaaaa
    11881 aaactgatac tgcttgattg attttaagtg ctccttgact accgccaaaa atcaagactg
    11941 ttttcttttc tggatccaaa tcaaatgttt tcaaaatatc tgatttttta gtatctgcta
    12001 cttcttgtgc tcgaggatta cctacaagaa ctgctttgtt ttcaggaaaa aaggaagccg
    12061 catctttaaa tgaaagagcg atccgatcca catatcggct taaaaattta ttggtaacac
    12121 ctggtacact gttttgttca tggataactg ttggaatacc cattttggct gcagcgtaca
    12181 ctaccgctcc ggaaacatat cctccagtac cgataacgat atctggttga aaatcactga
    12241 ggattttttt tgcttgacgg atactcttaa gaaacaatcg gaccgtcttg atgttatgca
    12301 tggaaatttt tcgtttaaat ccttgaatct ccaaggtatg gaaaggcatt cctgtatcag
    12361 ggacgatttt gttttctaga cctcgttttg ctcccacata catgaattca gcattcggtt
    12421 cttgagtctt tacataattg acaaaggcaa gagctggata aatatgtccc cctgttcctc
    12481 cgcctgtaac caaaattttc attttttatc gctcgcttct actttttcta ttttaatcgg
    12541 ttcacagctt ccatgaatct gtttcctcta gtttcaaaat ttgggtattg atcccagctg
    12601 gcattcgctg gtgataataa aactacatca ccatctgtac tgttttctaa tgctaaagga
    12661 actgcttgtt ctacagaatc ggctgttact attgtctcga tgcctgcttt ttttccagca
    12721 tccatcaact tttcttttgt ttggccaaat acgaccattg ctttgattcc ttttaatgaa
    12781 ggaattaatt catcaaatgt atttcctctg tctaatccgc cagccaataa cacgacctta
    12841 gacgtttcaa atccacttag agccatttta gtcgctaaaa tattggttgc ttttgaatca
    12901 ttataaaatt ttctgccttg gatttctcct acatattgcg tacgatgtgg tacgccatgg
    12961 aaaaaatgca acgtttctcg tatagcttca tttgatatac catacaattt tgctacagaa
    13021 atagcagcta gtgcattttc tacattatgc ttacctggta cgccaagttc agatatttcc
    13081 attatttttt cttttttata gtatattgag taatcgtcag catacacacc gtcttccaac
    13141 acttcttttg tcgagaaagg cagtacgcgt gcttttgttc tttgcgctaa ttcttgtagt
    13201 tctgactgat tccagttaag gatcagataa tctttttctg tcatgttttt ttgaaggttc
    13261 catttagctt tgacatattc ttttcttgta ccatgataat caatatgtgc ttcatagata
    13321 ttggtaatca ccgctatatg agggcggaaa tctgtgattc ccatgagttg gaagctagac
    13381 aattccatca caattttatc ttctgatttt gcttcttgcg ctacaccact tgctggatac
    13441 ccaatattac ccgctaaacg tgcaattcct tgatctgctc ctgcattcag tagtagtcct
    13501 gtcatcgttg ttgtcgttgt ttttccgttc gttcctgtaa tcccaataat tgggcattcc
    13561 gctacttcgt aagctagctc aacttccgta attaccggaa tacccatttc ttgggctttt
    13621 gctactaaag gatgactgta gggaatccct ggatttttga ccatcaatga aaattcttca
    13681 tccaacaatt cgattggatg actacctgtt attactttta tccctaaaga aagcagctct
    13741 tgtgcttccg gattttcgtc aaaaggtttt ccatcattaa cggtgacaag tgcgcccaat
    13801 tcatgtaata atttggccgc acttactccg ctttttgcga gtcctaagac aagcactttc
    13861 ttattttcat atgttgatat ttttttcatt tcccgtcatc tcctaccaaa cgatccataa
    13921 tgtgatcaac gaagtcacaa tgctgatcaa ccaaaaaact gtatcaatct tccactccga
    13981 ccatccgcac atttcaaagt gatgatgaat tggagacatt ttaaaaattc gttttcctgt
    14041 aagcttaaag gaagtaactt gaagcatcac acttgctgtt tccataacat agatcaaacc
    14101 aatcaaaagc aatgtccatt cttggtttag cattatagaa attgccgcta aaagtccgcc
    14161 caacgctaat gaaccgacat ctcccataaa aatcttggca ggttttctgt tgtagacgaa
    14221 gaaacccagt aaacctccta aaacacttaa gcaaatgatt aatacatcat actgatgctg
    14281 atgccaagca attagaccgt aagctgcaaa agagatactt cctaagccag caactaatcc
    14341 atcgatgcca tctgtcagat ttactgcatt tgaaaatcca acaagccaga agagagcgaa
    14401 aataccataa atgattccta aaggtagatc tagtccgaag aaattcaata cacctggata
    14461 accttcagaa cggtaaacaa gataaaagat gattccccct agaatctgtc caatcaattt
    14521 ctgcttcgag ttcagtccca tgtttctttt cttgaatatt tttataaaat catcaagaaa
    14581 gccgattact ccgtataacg ctaatacaaa aagcaagatg aaaagagtag gagttagctg
    14641 tttttgccaa gctccaaccc aaattcctgt caaaatagag ccgatcagaa acactaagcc
    14701 gcccattgta ggagttccgg ctttgctatt gtgccacttt ggtccctcct cacgaatcgc
    14761 ctgaccttgc tttttcattt gaaaataacc aataaatagc ggcattgcgg caattgtcat
    14821 tgcacaactg ctgacaatgg gaatcaatgc ttgtgtccat tccatgctct tttctctcct
    14881 atttctcttc ttattcttct aaagtaaaac taagtttgtc ttcagtgatt ttttcatatg
    14941 gagcaagttc ttgtttgaca caataaccat ctccatcaaa actaacttca ataccgagga
    15001 ttttccccag cttcatgata tctgcttttg accatcctgt tacgtcaggc atcagcttat
    15061 caccaccagt atataggatc agtttttctc cagagatcaa ctgatcaccg ttggcagtag
    15121 attgtttttg tactttttta ccattaccga tcactacagg ttgcagtcca cttttttgag
    15181 catcagctgc tgcaacgtcc gcttcaagat tacgataatc ggctacggat actttttctg
    15241 tttttgtttc tgtatctgaa tcttcttcag tttctttaaa atccattgcc cgtttcatca
    15301 atggatttgc gattttagcc aatgccattc gatcatatgt cttagggtgt ttcattgtta
    15361 gatacaagac atagtctgga tcttcagaag gaaccatctc cacaatcgaa tacaggtagg
    15421 ctgtatctcc tgtttgatat ccccctgtat cagaagcgat ttgggctgtt ccggtttttg
    15481 ccgatacatt gtatccaggt acactatata caccataagc actaccgtag ttttcgcttt
    15541 cgacaacatc tctcatatat tcacggactt tttctgttgt ttcttttgaa aaaggttgcc
    15601 ctagaacttc tgtttgagtt gttcgctctt ctccagtttg gggatccacc actttgctga
    15661 tatatcgagg ttgaatcatt gtaccgttat tcgcaataga agtgaaagct ttcatcattt
    15721 ggaaattcgt cacacctacc gcttgtccat aagcactcat tgctcggtcg acaatattta
    15781 atgtaggtaa agcaccgttt acttcatcat ctaatccaga atgagtactt tgtccaaatc
    15841 ccagtttttg taaatagtta taccatcgtc cgcctaatcg ctgttccagt atgaccatcc
    15901 cgacgttagt tgaccatgaa agagcttgac gcatggtcag cacacctttt tcaccaaagt
    15961 catggtcatt gatcgtagca tcttctactt ggatttttcc agattggaag gtttcattct
    16021 cgttgaattc tccttcttcg atagcagctg cagtagtgaa aactttcatg gttgatcctg
    16081 gttcataact atcttgtacc aagaaattac gccagatagc atcttttcca gtcaatcctt
    16141 ccattgtttc aggattgaaa gtaggtcgtt gtcccattgc caagatttct ccggtttttg
    16201 ctttcatcag gactgctgtc aattcttctg gctgatattc ttcatttact tgatccatca
    16261 gtgtttctaa ataactttgt agtctgctgt ctaaagtcgt gtagatatct tgtccgtcga
    16321 cagctttttc ttcttctgcc actgtacctg gcagaggatt ttgaaaatta tctttttgat
    16381 aaataatctt accatcttta ccgctcaaga tatcattgta agcagactcc aaacctagtt
    16441 taccaactaa gccattctca tctttgtctg gaactgcgta tccaataaaa tgagaagaaa
    16501 agacgccatt tggatacatc cgagcctgat ggtcgacaaa ataaagacca gcgacacctt
    16561 cttttttcat gtccgcttcg atgttttgct tggtttcttg ggagatattt ttcccatagc
    16621 taccaaattc aacttgatac agctcttttt ttgcgccgtc ctctaaaata ttcagtgcat
    16681 cttttttgtc tatagaaaga ttcttatgca ggatttctgc tattttatca aaattctttt
    16741 cttcaacata cagtttttta tccccagagg tatatgtttt tgagagtatc gctttaattg
    16801 aataagagga ggcatcttct gcgagcgcca caccgttacg atcataaatc gttcctcttt
    16861 ttgcttttac tacttcactt ccttggtaca actgttttgt tttttcagct aatgaggtac
    16921 cagcaacatg acctccaata acgatatacg agaaacggac ggcaaataaa aagaacaatc
    16981 caatactcgt agcaaataaa atgataccta cttttttgcg attgttcatc ggatttagat
    17041 ttttcttttc cataaaccgc cgaattttat ttttaagact catttacttc actttcctta
    17101 aattgtcgtc attaatagac aatccttttt cttctgcgat ttgtttaatc cgttcagtac
    17161 gagaaagttc gtttttttct tgttctaaac tcgttttttc ttgcttttta tcattgattt
    17221 ctgtttgtat tgacgtgatt tctttttcag ctccgctgat atttgtgcgc agcataactg
    17281 ttaaaacaca taaagcaaca atagcaatcg ccacgcttgc cacagcaatt ttttccaaag
    17341 cagaaatctg ctttaatcgt tttgccggtg attgtggaag aatgatttct tgattcgaag
    17401 aagaatcagg catttgttgt tccggctgat ccaccaattc aggtaaatca tattcgtaat
    17461 cttgcatttt ctttaattct gccatcattc tactcctctt tcattcttat tttttctgca
    17521 atacgtaact ttgcactgcg tgatcgattg ttttctgtta gctcttcctc tgaaggaagg
    17581 attggtttac gagtaatgac tttcagttct ggttggaatt cgtcaggtat gacaggaagt
    17641 cccggtggta gatcttgtac cgtactatat tctttaaaca tacttttgac aattctgtct
    17701 tccaatgaat ggaatgtgat tacgctgatt cttccattga ctttcaataa ccggattgcc
    17761 tgttctaaag aggcctcttc ggcaccgagt tcgtcattta ctgcaatccg cacagcttga
    17821 aaaattcttt ttgcaggatg cccgcctttt cttcttgcgg gagctgggat gacttgttta
    17881 atgatttcga caagctcacc agttgtttgg attggttttg tttttcgtac tcgttcgatt
    17941 tcacgagcaa tttgtttgga aaatttctcc tcgccatagc ggaagaaaat ctttactaat
    18001 tcatggtagg aatattcatt aattacgtga taagcggata aaggagctga ctgatccatg
    18061 cgcatatcca acggtgcatc ttgatgataa ctaaatccac gttctgcttc atctagctga
    18121 ggagaggaaa cccctagatc atacaaaatg ccgtctacct tatctacatg ctcactcaag
    18181 cgttcttcta attctctgaa gttcgctttg ataaatgtga ccataccttg ttcgacataa
    18241 gaagctaaac gcagcttggc gtgatcgatt gctttttgat cttggtcaaa cgcatacaga
    18301 tgccctttag aacttagttg gcttaataaa tattcactat gtccggcacc gccgagtgta
    18361 cagtctacat aaacgccatc cggtttgatg ttcaatccat ctaccgtttc tttcaacatg
    18421 actgtatagt gttgaaatgt ttcagtcatt agtcagcctc ttcctattct tatagtccga
    18481 aatcaatcat actttcagca atttcgtcaa agttctcttc tgctgctgca gaaaaatctt
    18541 gccatcgtgt ctcatcccaa atttcaattc ggttagatac accgatgact acgcaacctt
    18601 ttgtcaaagc tgcataattt cttaacgtgc tgggtatatt gattcgtcct tgtttatcaa
    18661 gttcgcattc agtggcagcc gaatagaaga atcgcacaaa agtacgtgcg tcttttttag
    18721 ccaacggcat ttcgttcagt ttagcttcca gattttccca ttcgctcatc ggatagccga
    18781 aaagacagcc atccaatccg cgtgtcagaa caaacttttc gccaagttct tcacgaagtt
    18841 ttgagggcac gattaaacgt ccttttgcat caatattatg ttggaattca cccatcaaca
    18901 ttgaaagccc cccattcctc cactaactaa aattagtcta ccacaatccc ccactttcta
    18961 ccaccttttc tgggaaatcc gggaacaact ttttttattc ataaacattt ttttaaaaat
    19021 caagctgcaa aaagcctttt aaaagacttt ttacagcttt tctatttttt tcataggtaa
    19081 gaaagtatgt tcacaatgat caagacagcg tacaagacga ttgtcaacag aaaaaccaaa
    19141 cgccaagtca tcttgaaata acgcggataa ataatttctt cataataata tgcttggaaa
    19201 acagcaatac aaattcccat tagcaaaaca gaaataaaga aaaacggtaa gatagaaatt
    19261 gtccctgtat ttctagacaa tgcatgcata ccgccccaca aaaaaggaat cgccaaatca
    19321 ggggctttta ttttaaaacg acgatttaac gaaaataatt ttacaagaaa ttggcaacca
    19381 aacaaaacga ttaccgggta aatataccaa aacaagataa gtggtgtgaa tgtgcccatg
    19441 aacgtaaact ccttttttat cgttgcttca agtatactgt atatacttta cacaactgtt
    19501 tcattttatt taaatttatg cagttatatt ctatatctta caaacacatt ccatgtattc
    19561 caattcccta tccgttataa taaaagaaac aggcaacagg aggaaaatca tgatcaaata
    19621 ttttacatta gataatgaga aactgcgtaa taccggaaag gaaactgacc aaacgatctg
    19681 gtattgtgta gaacgtccta atcaagaaga gattcatcag ctgacacatc aatttgaaat
    19741 tccgtcagat tacatcactt ccatattgga cgatgcagaa aattcccgta cagaagaatt
    19801 caatcaatca aagttgacaa agccagcgtt attattgtta caatatcctt ttgctaaaac
    19861 aagtcctagc ggttattttc aagtggatac atacccgctc tctattattt tgacgcccaa
    19921 aaagaagctt atcacaatta cgaatcatga accactgttt ttaaagaaag tctttagcca
    19981 gacctttcca aaaagtgata tttcgcctaa tctcaatatc ttctttcaat tcatttggca
    20041 ggtcacactc tcttacaaca gttatttagc tacgcttcaa tctcaatgcg atactttgga
    20101 agccaaactt caagtatcca ctgaaaacaa acaactttat caaatcatgg atatccaaaa
    20161 aagcctcgtt tatttcagag aagcgacttc tgctaattta gatgcattga aagaactagc
    20221 gcaaaataaa cttttccaag aaaatcatgc tttgaaaaat catttacgtg atgtattggt
    20281 ggaaacagag caggcaatga ctacttctcg cattcaatta aaactagtag aacaaatgaa
    20341 tcagactttt tcagcaatcg tatcgaataa tctgaataat attatgaaaa ttttaacttc
    20401 tttaacgatt attttaacta taccgacaat cgtcggcagt atctatggaa tgaacattaa
    20461 gttacctatt gctgaaaggg atgatgcctt tatatggcta gttctattaa cattatttat
    20521 ttgtatcgta actacctatt atttaaaaaa agggaagttt ttataaaaaa gccctcttgt
    20581 ggaaatggaa aaaagattgt acacttgaat caactaatta atgacgaggt tgaaaacaat
    20641 gcgtgaaaaa aaacaaacaa gtacttttgc taaagtaaca aaatttgtca tttggacaat
    20701 gctgatttta acgattggat ctgttgtatt gactgctgta atgagtgtca tgtaaaaata
    20761 aaatatagct atcagctgct gaaaaggacc tgaaccactg cgaggtggct caggtccttt
    20821 ttgcgagttt caatagttct tttgcatgtt cgagtgtgag ttttgtaatc tcacttccag
    20881 ccagcatacg tgcaatttct tcttctcttt cttttgtttt caactctgaa acagaagttt
    20941 gcgtacgtcc atcaatcact gctttcacaa tataatattg atagtcggcg actgcagcaa
    21001 cttgaggcag atgagtgatg cacaaaactt gagagtattt cgatatttga gaaattttat
    21061 ctgcgatggc ctgtgcaact cttccgctca cacctgtatc cacttcatca aaaataatac
    21121 ttgtcacacc ttgctcagaa gaaaaaatag ttttcaaagc aagcaacatc cgagacagtt
    21181 cgccaccaga agcgactttc accaaaggct tcagtggctc tcctggattg gtcgtaatgt
    21241 aaaattcgat ttggtcaaat ccatcatgat tcaattgtct attttcttct tttaagaaac
    21301 gtacctcaaa ctcagtgttt tccatataca gacttttcaa ttcatgcaga atggattttt
    21361 ccaattcttt tgcgattttt ttacgcgctt catgaagatc tgcggcttgt tgctgaagta
    21421 gaagctcttt ttgctctagt tcctctttca ttttgtccaa ttgaccttct gaaaaatcag
    21481 aagaagctag ctcttcggtg atttcgtcat agtaagccaa tattgactca atggattcgc
    21541 cgtatttacg tttcaactgt cggattaatt ctaaacgttg cgtaacttct tctaaacgac
    21601 tctcatctaa ctccaataaa tcaatctgac gactcatatc gccgattgca tcttgcagca
    21661 aatagtaagc actttggata ttttcataaa ttgcttcata ctccacatct agatgggcga
    21721 tcccttgcag ttctgaaacg gccaagccaa caccatctac actgttttgt tcattattcg
    21781 tcagtgctcc gtaacctgca gctaatccat cagcaatttt ttgataattg ctaagttttt
    21841 ctctttcttc ttttaatttc tcttcttctc cgacttgcaa atcagcagca gctatttctt
    21901 cttgctggaa atggagcata tctattctct gaacatagga tttttcattt tgctgcactt
    21961 ttcgtaccct tttttccagc tcacgataag agatatattc ttgctgataa ctctttttct
    22021 tctgttggaa agctacatct ccaaaacgat ccaataaagc aagatgtgat tcaggctgga
    22081 gcagttcctg atgttcgttt tgtccttgga tatctactaa ataactgccg attcttctca
    22141 gattagctaa tgtgataata tgaccattca ctcgacaaac attttttcca gttaaggaca
    22201 tatcccgtcg aacaatcaga ttgtcctcat ctgtttcgat ccctaattca accatcagtt
    22261 cagagaatcc ttcttgtttt ggtagttcaa acaacccttc aagcacacat ttttctgctc
    22321 cttgacgtat ataatcgctt gaacctcttc ctcctgctaa cagacctaaa gcatcgataa
    22381 taatggattt acccgcacca gtctctccgg tcagcgcggt cattccttcg tgaaaagaaa
    22441 gccgcaattc cggaataatc gcaaagttag taatactgat ttcttgtagc atcacattcg
    22501 ctcctcaact taaaggtaat gcaggaagtc tttcttcaat aaaactgcct ggtcttcagt
    22561 tcgtgtaatc atcaaaacat tatcgtcatc attgataatc gaaaataatt ctttcttgta
    22621 acgtttatca atcaaatttg ctgctgccga agcatttccc ggcaatgttt tcaaaataac
    22681 aaatttttcc atttggtcaa ctgccacgaa agcgtctttt aatagttttt ccaatttagt
    22741 atttacatct tcgtttgttt cagctggtat gctataacgg tagccgccat ctgaagccgg
    22801 taccttgatc agtttcagtt cctttatatc tctggaaatc gtagcttgag taacagatat
    22861 tcctttgctt ttcaggattt caacaaattc ttcctgcttt cggatatctt gctcactcaa
    22921 caatcgagta atcaaacgat gccgatcttt ttttctcatt acgtcttcgc tccttagcat
    22981 attcttctta atcaatgata gcttatttcc ttggtataat aaagaagaat ccgcatactt
    23041 ctcacttgat tttcacagtt acaatttatt tatggtcaaa ctgttcgtgt gcatttgaaa
    23101 ccacttctgc catattaata gctgaattga ttgttccgct ttcgggtact ttcctcaagt
    23161 gagccaagaa ctcgatattt ccttctcccc ccgtgatcgg agaataactt aattccagca
    23221 catcatatcc accttgtgcc gcaaatgaca aaatgtcttc taaaactttt tgatgggtct
    23281 gagggtcacg aacaattccg tttttcccta cagcttctct gcctgcttcg aattggggtt
    23341 tgattaaagc aatcacttct ccctcttctt ttaaaatagc atgtaatgga ggcagcatca
    23401 gttttagtga aataaaagaa acatcgataa cagcaacttc tggaattcct aaggtaaagt
    23461 cttcgggttt tgcataacga aaattcactc tttccattac gacgactcta ggatcttgtc
    23521 ttattttcca agctagctga ttgtagccaa cgtctaaagc ataactcatt tttgcgccat
    23581 tttgcaaagc tgcatcagta aatccgccag tggatgcacc aatatctaac aatgtttttc
    23641 cttcaacaga tagatcaaat gctttgagtg ctttttctaa ttttaatccc cctcgagaaa
    23701 cataaggaag ttttttacct ttgactctta attcactact cactggaatt ttttctcccg
    23761 gtttatcaaa ccgctcgttt ttttcgttgt aaatcaaacc agccatcact gaacgtttgg
    23821 cttgttctct tgtttcaaat aatccttgtt tgaccgctaa tacatctacg cgttcttttt
    23881 ccattctttc cctcatttct ccacatcaaa ttgcttgatc atctggcgca tcagcccgcc
    23941 atcaaaagaa aaaacgtcct cttctaattt gtctatgatc ttgttggcgg ataacagctc
    24001 aatctccaac gcctcacgtg tcttttctag gcctaataaa cgcgggtaag tatttttttc
    24061 catacgttca tctttaccag ctgttttccc taatgttttc gttgtaccaa tcacatcgag
    24121 tagatcatct cttatctgaa aagctaaacc taaatgttcg gctaatcgtt gaagtagcaa
    24181 taagatttct tcaggttgct tcgctaatat gccaccagcc agcaaggcat aacgaatcaa
    24241 atgccctgtc tttctttcat gaataaatgc taattcttct aaagaaagct ttttcgattc
    24301 gccctcgata tctgcagctt gcccagcaac cataccttgt gatcccgcac aaacagctaa
    24361 ttgctgaagc agcagaagct taggagaatt acctaagtgt gccatactga ttagctggaa
    24421 tgctcctgta agcaaaccat ctccggccaa tatagctaat gcttcgccga atactttatg
    24481 attggtaggt tttcctctac gaagatcatc attgtccatc gcaggcaaat catcgtggat
    24541 caaggaatac gtatgcacca tttctaaagc agctgctact tgatagacgg gaacatcaat
    24601 aggctcatca aaggaagcaa cggccgttaa aagtaataag ggacgtattc ttttcccgcc
    24661 tgctttcact gaataactca tcgcatcata gagtcctcta tccgttgtat gctcatctaa
    24721 aaaagacaag atttcttttt ctacagcagg tagatgaata gctgaaaagt cagttaatct
    24781 catctcagct ttcctcgttt ccgtcaaaat caacttcttc atttgattct gtcatcattt
    24841 tcgtcaaggt ctcttctgct ttagctaatg tatcttggca atgtttgctt aattccattc
    24901 ctcgtttaaa cgaatctaga gctgattcta atggaacgtc tccttgttct aactgcatga
    24961 caattttttc taattcttgc agtgactctt caaaagttgg attttccata tttttattct
    25021 cctttgtcta tctcttgtac ttgtccttta acgattccat cttgataatg gatcgtcagc
    25081 aaatcccctt gatgaatctc ggtgacactt tttactactt gatcatttaa cgtcgtatag
    25141 ctgtagcctc ttcccatgat tttcaatgga ctcaacaaat caagagattg aacagcttga
    25201 gcaaaacgct gctgctgttg tttcatatat tgttggattt tctcttctaa gcgtttttct
    25261 agataagcag tttcttggcg agctgcttta actcgataaa gcggagccac ttgttccaat
    25321 tggtggctta atgcgatcgt ttgtttttct ttcgcatgat aaatttgctg tgtagcttga
    25381 tataatcgct gtttcaactg gtctaatttg atggtctgac cttcatacaa tctttcaggc
    25441 tgccgaaata cataggaacg tcgagcacgc tcgaaccgtt cttgtttgcg ctggatctgg
    25501 cgtacaaacg cctgctgcaa tctagcttgc cgttcttgaa tgcgcatcaa ctcttctgac
    25561 aaaacaggaa cagctaattc tgcagctgct gttggagtgg cagcccgaac atctgctact
    25621 aaatcagcga tcgtggtatc tgtttcatgt cctacagatg aaatcaccgg cgtattagct
    25681 tgataaatcg cccgagcaac ccgctcttca ttaaacggcc ataaatcctc aatcgaacca
    25741 cccccacgac cgatgatcat tgtatcgaaa ttgcccatct cttctactct ctggatattc
    25801 ctgacaacat tgtccgctgc ttggtttcct tgtacaactg ttgggaacaa aaccaattgg
    25861 acaattggat atcttctttt caccgtcgtg atgatatcgc ggataaccgc tccgcttgga
    25921 ctggtaagga ccgcgattcg ctttgggaaa cgtggcagca tttttttagg cccttgaaaa
    25981 aggccttcct tcatcagctt ttcttttcgt tcttccaatt cttgatataa agcacctatt
    26041 ccatcaggct ccatgtgctc tacatagatt tgataagaac ctcccgcttc atataatgaa
    26101 atacgcccaa cgacaaggac tttcattcct tcttttggct ggaatcgtaa tttttggaat
    26161 gctcctttga acataatagc agatattttt gcatggtcat cttttaagct gaaatattga
    26221 tgggcattgg cacgtaaacg gaaattcgat atttcgcctg ttaaatatac gcgttctaaa
    26281 taaggatcgg catcaaattt tcttttcaaa tacttcgtta atgtagtgac agttaaatat
    26341 tcttgtgcca tctattcacc tgctccaaaa gcttcggcag attttacggt ttgatacatc
    26401 agcatcgtga tagtcattgg ccctacaccc tttggcacag gagtgatcca gcctgcaata
    26461 ggctccactt catcaaattt cacatcaccg atcagcttac cgttagcatc acgattcatc
    26521 cctacatcta tcactacagc acctggtttt acgaattctt ttgtgacaaa atgtccacgt
    26581 cctattgcta cgactaaagt atctgcttct tgtgccagtt cagccagatt ttcggtttta
    26641 gaatgagcaa cagtaacagt tgcatctgcc atcaagagta gctgagccat cggtttaccg
    26701 acgatattgc ttcgtccgat aactactgct cgtttacccg ccggatcgat agaataagct
    26761 tcaaacattt tcatgatgcc gtatggagta caaggaatct tgtccggttt acccgcaagg
    26821 agtctgccta aattcatcgg atgaaaaccg tctacgtctt tttcagggcg gatagctaac
    26881 aggatctttt cttcatctat atgctttggc aatggtaatt ggaccaatat accatgaaaa
    26941 ctaggatctt gattgtattt ttcaatttct gcaagtagtt cgtcttcaga aatcgtctca
    27001 ggataacgct ctaccaatga atggattccg atttcttttg ctacacgttc tttatttctt
    27061 acatagattt ggctggctgg attttcccct accaataaaa cgactaatcc gggatggata
    27121 ccattatctt tcaatttttg gattttttca gcaatctctg cctgcatttt ttcagctaat
    27181 tcttttccgt taatcaattc tgccatctaa ccactcccag atattttttg tgttttcatt
    27241 ctaccataga attttcccga tttataacag gtttatgatg attcatagaa aaaagctagg
    27301 acttacgccc cagcttctaa ttctttcaat acattggata aaacaccgtt gacgaattta
    27361 cgtgaacggt catcactaaa tgtttttgcc aactcgattg cttcatttaa agcaacagcc
    27421 gctggtacat ctgtcacata agtcatttca aaaatcgcga tacgcaagat caccaaatcc
    27481 atttttgaga tccgattgat gtgccaattg ttttttaaat gtttttcaat cactttatcc
    27541 aattcatctt tttttgcaca gacaccgcca actagcgtat caagataaac aggaacaaac
    27601 tctgattcat cttcgttgat catgtcgcgg tggtctaatt cgattgcgtt gaaaatcgca
    27661 tcttcttttg ttaggtctgc attgaagtct aatggaaata aagcctgcaa tgccatttcc
    27721 cgaatctcgt gtcttgataa ttctttattc attctcttcc tcttcgtctt caaaaagttc
    27781 ttcgattgtt ggttgttcta atttttcagg aacaacagct actacatgga tattgacttc
    27841 agataaatcg atatccgtca tgaaaaggac ttgctggctg acccgttcct gcatttccat
    27901 tgctacttta ggaactgaaa caccatattc tagataacag taaagatcta ctttcaagcc
    27961 atcttcctcg tttgctaagt aaacaccttt tccgtgagct gcacgtccta ataattcagt
    28021 gacattgctg gcaaaagttc cgcgcattcc gtatacgcct tctactttag aagctgcaat
    28081 cccgataatt acttcgatga cttcaggagc gatcacgatc tctcctaaat cttggtttgc
    28141 gtttaaaatc aaattttttt catctgccat ttatttattc ctccctttgc ctaagcacga
    28201 gatacatccg aattctctat gatgcggcat agtgatcacg tggtaagaaa actgccgccg
    28261 atcagctgca aactgctatg aattggagaa aacacccaac tttattatct cttacagctt
    28321 aaaagttctt ctatagtgta tcattaaatc gagtgatttt ctataacaaa gtctgtgaac
    28381 actgattttt acgcttactt cttctatcga tgaaactata agatgatcaa ttcttttggt
    28441 gaacgagtca acacacgatt tccatcttct gtgatcaaca agtcatcctc aatacgtact
    28501 ccaccgattc ctggtaagta gatccctggt tcatcagtga tcacatttcc tggtacaaat
    28561 tgcttttctg cacgagaaga aacgtttggt ccttcgtgga tctctaaacc gatcccatgt
    28621 cctgtagaat gtccaaatgc ttccccgtaa ccatgttttg aaatataatc tctagcaact
    28681 gcatctaatt ggacaccagt cattcctggt tttgcagcat caataactgc taattgagca
    28741 tctaagacta tttgataaat ttcttttaat ttttccccag gatcaccaat agcgaatgta
    28801 cgtgtcatat cggaaacgta cccttcgtaa tagcaaccaa agtccaatgt gatcaagtca
    28861 ccttgttcga tgattttttt gcttgctaca ccatgcggca tagccgaacg caatccgcta
    28921 gcaacgatcg tatcaaaaga aacacctgaa gcgccaagag aacgcatata aaagtctagt
    28981 tgatttgcga cttcaatctc agtcatgccc ggttggatca ttttcaggat gtgatcatat
    29041 gccatatccg caatatgaca tgctttttcg ataatagcga tttcttcttc atctttcact
    29101 tctctgagtt cttcgatcat ctgtgaaaca ggtactaatt ccgcatcgat gatttcttct
    29161 aaaaccgaat attctaaaaa tgagactgtt gtttcctcaa aagctaatga gtgcagttct
    29221 tctttgcgta ctaagtttgc tacctcatca aaaataggtc cgacattttt aataatttca
    29281 aacccttgag cctgcgctgc cgcctgctcg gtataacgaa aatcagtaat aaaaaatgct
    29341 ttttccaaag taataacagc taatcctgtc gtacctgtaa agttcgttaa gtaacgaaga
    29401 ttgtacggac tggtaaccaa aaatgaatcc aaattttctt cttgcatttt tttgcgcaat
    29461 ttttctacac gtagcatcat aatgaaactc cctctttctt tgcacgcttt tttccattat
    29521 agcaaacttt tcttcgtaca cgacagttaa ataaaaattt ccggaaaact tctttttatt
    29581 ttaaataaat aaagccaaaa aggagtcaca gtctcgctgc aactcctttt agtttactat
    29641 tttgtaaaaa cttatgatcg ttttccaaag aaaaatgaga caactgctac caaaatcact
    29701 gcgcctaaaa tagatggaat aagtgccata cctgcagctt ttggtcccca ttcgccgaaa
    29761 atcgcttgtc caatacttga accgactagt ccagcaatga tattcgttac acagcccatc
    29821 gaatttcctt tactggtgat cgcacctgca attgctccga tcacggctcc aacaatcaat
    29881 gtccataacc aactcataat ataacctcct tctttgctaa tcaattttag catatgggat
    29941 ttaaagggga caaataattg gttttgctat ttcatatttt cttctgcaaa gtaaaaaaat
    30001 aaagaaaacc tcctcttaga agttttcttt attttttact tgcgtttaaa catactacga
    30061 ataccacgtt tcactacatc aaagaaactc aatgattgta ccattctatc ttcatctaca
    30121 tattctctga tcgcacgaag cactttttta ggttctttgg aagaaaatgt gtatgtacca
    30181 ttttttttcg tttgaatggc atatcgagga atccattttc cctttagcat gactgatgct
    30241 agtacataat ccacttcttc ccatggaatt tggatatatt tgcgtctatc tcgcgcatgg
    30301 taaaactcaa aaccattatc acctatcatg atttgcccgt aatctgtcag acccgtaaac
    30361 gaagtagcat caattaccaa gtctactttt gtattgattg attgaaccat tttctccctc
    30421 cagatatttg tttatgaaca gtatactata taaaaaaagc tcgggacaac gcccgagcta
    30481 tatttttatg gattataaaa gtccgatgac gtgtccaaca acaccgacta cgaataaacc
    30541 aaggatgata acgattggag aaaccttttt cttaagcaac cacatacata acaatgttaa
    30601 tcctaatgca gctaaaccag gaatcaattg gtctaagttg tcttgtaatg ttgttacctt
    30661 ttcaggagaa agggctaagc cattattaac ttgttcaaat gcactcttga ttccttcacc
    30721 acctgaaggc aatttatccc attcgatgta agcaccttta tctaatttta cagttgatac
    30781 aactggtaag aatttgattg atacccatct ttgtacaagg gcagctaata cgaacatccc
    30841 taaaattgaa gcaccttttg ttacgtcttg taacaatccg ccagaaaggt catcagtaat
    30901 tttagaacca gctttgtagc caaattcttg tgtataccac atgaatgccc aacgaataat
    30961 gttccaacct aagaagaaga tgattggtcc aaggatattt cctcccatag ctaatgaagc
    31021 acctagtgca cctagcattg gacgtactgt aaaccagaac actgggtcac caacaccagc
    31081 taaaggaccc atcataccta ctttaacccc ttgaatcgct acatcatcaa caggcgcgcc
    31141 attcgcacgt tcttcttcca gagccaatgt aacccctaaa attggagaag caatgtatgg
    31201 gtgtgtatta aagaattcca agtgacgttt taatgctgca gaacgttctt cttttgtttt
    31261 gtataatttt ttgattgctg gaatcataga aaatgcccag ccaccgtttt gcatacgttc
    31321 gtagttccat gaaccttgaa tgaaggtaga gcgccacgca acagctaaac gatctttttt
    31381 tgataatttg attttttctt ctgccatttt attttcctcc ttcaagatta atagtcattc
    31441 aaaatgtcgc ctaaagggtc accagagttg cttccgcctc cattatttga tgaaccaccc
    31501 attttagaaa ggttcaagta aataagagct aatgcaacac ctaaagcacc tagagcaatc
    31561 aatgttaatt gagaaattgc agctacaacg aaaccaataa cgaagaatgg ccatacttct
    31621 tttgtagcca tcatgttgat taccaaagcg taacctacag ctacgaccat tcccccaccg
    31681 atagccatac catctgttaa ccatgctggc attgattcaa ggaatgattg cacagtttgt
    31741 gctgggataa atagcaacgc tgctgctggg accgcgatac gaaccccttg taaacataca
    31801 gcaatgatgt gccacatttc aaccttacgg atgtttcctt cttcagcagc cgcatccatc
    31861 aaatgaacga ttggaacagc gattgtacgt acgatcattg ttaagaacaa ccctgcaaca
    31921 gccaaaggaa cggcaatcgc gatcgcagaa ggaacacctt taacaccttg tccacctaaa
    31981 actaaaataa ttgctgatgc tactgatgct aatgcagcat ctggtgctac agcggcaccg
    32041 atatttgccc aacctaaagc gatcatctga agcgtaccgc caagtacgat accagcttcg
    32101 aggttaccgg taactaaacc gatcaatgta catgccacta gtggttgatg aaattgaaat
    32161 tcatcaagaa taccttccat accagctaga aaggcaacta atacgactaa aattattgaa
    32221 ataatagaca tgataagcct cctataaatt ttaatattat ttattacgct tttgctaatt
    32281 cagcttttgc ttttttcaaa atatcatcca tgttatcgcg tgaatcatta ggtactttac
    32341 gtacatcgaa tttcacacct ttttgttcaa gcttctcaaa cgcttcaacg tcttcttgtc
    32401 ccatagacaa tactttactt acaacgactt taccgaccga atgcgccatt gacccaacat
    32461 ttaattcttt gatgtctacg ccaccttcaa cagctgtcaa tacgtcttca ggattttcaa
    32521 ataaaagcaa tgctttggta tttccaaaac gagggtcttt tgctacttcg atcattttgc
    32581 taataggaat aacatttgct tttacacctg gaggagcagc ttgttcgatt agtctcttac
    32641 gcagatcatc ctttgatact gcatctgaaa caacgataat acggtttggt tgcactgctt
    32701 ttgtccaagc tgtcgcaact tgtccatgta acagacgtga gtcaacacgt gctaatacat
    32761 atttgatttt tccgtctccg accacagttc cttctggaag tgctccttta ggttgtgcgt
    32821 cttcaactgc tgctttcggt gcttctgccg gttctaattc ttccggtttt acttttacac
    32881 cgtcttttgc tgtttcaatg atgtgtgctg caatttcatg agcagattcc attgaaaagc
    32941 gtgatgcgta ggcttcaatc aacattggta aattcaaacc gctgacgatt gcccatttat
    33001 ctttgtgctc ttcgaataat gtgtttgatt gattgaacgg tgttccgccc cataaatcaa
    33061 ctaagaataa cacttcgtct tgattatcaa aagaagcaac cgcttcttcc aatttggctc
    33121 tcaagtcatc tggaccttca cttggtttca aaatcacggc tttgacgttt tcttgttcgc
    33181 caaagatcat tgaaccggat tgtaagattc cttcagcaaa ttgtccatga cttgctagga
    33241 taatccctac catatttata cctcctattt acttttgttg taacaaattc aaaaatatta
    33301 ataattgcta accattacaa cagaattatt tgaccttttc caacaaccat tcttgctaca
    33361 cctttttgat tttcgctagt agttccatca aaaggatttt cctgtcagca ggtacttttc
    33421 gaatctctaa ctccacttct tgactgttca agtaacgaaa ggaatcaata tcttgttgat
    33481 ttactgaaac aaaattggta atcattgatt tgccttcagt aaaactcata ccgccgatat
    33541 tcaacgactt caactgtaca ccgcagcgga caaccgcttc aacatcttgg ggattggtga
    33601 ataaaagcat cacttttgct cgtgataata atccactatg atagatttga atcattttct
    33661 gcacggttat tacatttgct gtgatccccg gcggtgcagc ttcttttagt agaaactttc
    33721 tcaatttatc ttgagcgact acatcgctga tcacaatgat acgttcaaca cctgtttgct
    33781 tcgaccaaac tgttgcgact tgcccgtgga ttaaacgatc atctatacgt gccaatcgaa
    33841 tatccatctg caaaactcct tcttcctcac tacttcacag aaacccctat catttctgtg
    33901 tgaacaacca cctcctagca cacactacta taagcaaaaa gcgtgccaac ttttttacga
    33961 tacactaatt gaatttaaag gattcttaac caatacacaa aaacgataca ctataaaagt
    34021 gtatcgtttt tgtgtattca tggcacagtg tattcttttt tatctaactg attatggact
    34081 agacgtagca gataatacat ttcttctatc ggcactttta cttttatctg atcttccaac
    34141 agaacaactg aggctgccaa ttggctataa agaggatcat tcgttgtatt tgtcaattcg
    34201 ttttcttcca cagtcaatgg ttcattccga ataatacgtt cgatcattcc tgctgtgtgc
    34261 atcactaggt tgattttgaa tccatattct tcatcgccga ttcccgtcgt ctgagagatt
    34321 tgtgtagaaa attgccacat tggatcgatt aacttactac cattaataaa gatgaagtta
    34381 tcagagataa actcaacaca cgtattttta gctgactctt catctaggga gatgaattca
    34441 gtttcctcca attctgattc catcagcaac tgatccaaaa tgacttcgat attttgatca
    34501 ataaaacgtt ctaaaggaat aaatggggct tggatattca aatcagtaat cccagtagta
    34561 gctatgatct gatattcttt ttggataact ggcagttctt ctttcacttc cacaatcgac
    34621 aaagctagaa cttctaattc tgtttcttga cgcttgttta ccgctcgttc gatcaattct
    34681 ttgattcttt gtgctgtacc ttcgccagat gcgcagatag ccaaaacagc ttttttctta
    34741 tgaataggtt ttgcttcctg aacagattct acagaagata tttctgcgta acctcgaaaa
    34801 tttttcaatg attcatgcaa catatctaga tctgtcccta atactgagac ctttcgtaca
    34861 gtttccaaaa ctagagaagt tgttaccata tcaacagtac gtactggaat tccagtgtct
    34921 ctttgaattt gcgaattaaa cgacgcaagg gaccccatat ctactaagag tatgaccccg
    34981 cttccttcat ctacttcttg tacattgcgt tcaattcggt ccaatgctgt tttcggatcc
    35041 atatccaaag gcatgtctac tgctcgtacg ttctctgcat ctaacaactg ttggacaact
    35101 tggaccatac tgcttgctgt gctgtttccg tgagctgcaa cgactacacc gattctgccg
    35161 cttgcttgat ttgcccgtaa cgagacgagt agaacggtca agtaatagtc ttcactttct
    35221 ggaatctcca cttgaaaata cgtttcgata taactacgca cttctttcgc aacagcatat
    35281 tcatctggaa aatcaaaagc catctcacgg atgttatcat tcgtatgccg ttcttctcct
    35341 aagttgattt ttttcaaaaa agaactgata tgcaagctca tagcataaat aaagttttgc
    35401 tgaaactcat atggtaaaga tcttttgacc attacataaa tctgattggt cacttctatg
    35461 attttcggat ctacaaattc tgctaatttg ctgtctgcat taaaagaaaa accatggtct
    35521 ttatagaaag acttcagatg gatgttgata tctgtagaaa tgaaatgatt gattgcttct
    35581 tgatccaaac catccgactt cagtaaagct gctttatctc cgatgatatc atatagatta
    35641 taaggtaact cataggagtc cgattggatt ttcatgatcg tatcatttgg tgctacagtt
    35701 atctttggct ccaatatttt agaaagctct gccattgcac tgcggttgct tgctaattga
    35761 atcaatccgc tacgaatccc ttctgtcaaa tcatcgattg tgatcgagat ttcgggtgat
    35821 tgcatatgat ttagaaatcc tcgtgcacat actaactgga tatttgactt caattgtcct
    35881 atatttccat aggtcacact gccgatcaat gcttttgcta catcttctgt caaagaaatc
    35941 tttcgctgcg tgcggtttgc ttcgtgggca atcatgattt ttactaaatc gactttctca
    36001 tttgcaggac gtttttcaaa agccggaagt ttgatattga ttgggatacg ccgaacaaaa
    36061 gtttctaata gagaagaacc tgggtcttct gtggtcgcac ctacgatccg tacatttgct
    36121 tcatgggatt tcgttgtttc cccaagacga ctgtaagttc catgatccat aaagtaaaag
    36181 atcatttctt gaccttcagg cggcaaccgg tgaatctcat ccaaaaacag cataccgcca
    36241 tccgcttgat cgataatccc cattttttct tcatctgcgc ctgtaaaagc accttttgcg
    36301 tacccaaata aatgactcat caaaagctca gggttattgg cataatcagc acaattgaaa
    36361 acaatcagtt ccgtttcctc atctattaca tgatgcgctt ttgcaaaatg atacatcgcg
    36421 tgtgcaaaat aagtctttcc tgatccggta ggtcctgtaa tcaaacaatt taatcctctt
    36481 ggcggataca aaatcgcagc ttttgcctgt tccactgaat ttttcatgct gccgttagct
    36541 ccaatgattt ttgcaaagat atccttagta tctatttgga gtgtattttt ttcttcagag
    36601 accggcgttt ctttgtaact gactacatgt tttgtaactg gctttacgtg cgtaacgagt
    36661 gtttgatata tgtaacgtac tggtcgtccg tctgtcttta tcagttttcc ttcgcgcact
    36721 agctgattca gatctttact gctatttgtt cgctgaatcc ctaacacttc agcaatttcc
    36781 tgtgttgtta ctccttgatc atattctgcc tttgttaaat gagcggtttt ttctttgaca
    36841 tacatataaa ttcggtcaat gcgttttgcc aatggtatcg ctccttttct atagactatt
    36901 gtacttaggc ttcaaaacat aatactatgt atttatttct gtttcgtcaa ctatttacct
    36961 gattttgttt tgttgataac acgcggatag atagaaatgt tcaatttaaa agaacgaaaa
    37021 atcccgatac gatttttata atggaaacaa gaaaaagaac actgtttacc atataattat
    37081 ttcactgata gcaaacaata tagcttccat caattgaaaa cgatagttat caaaacatcc
    37141 tgattccaaa ttggcaaaaa aatattaagt gtaaaaagac aaagtaaact tcgtagcctc
    37201 cactacaact ttt
//
LOCUS       DADVXB010000009        36569 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.009, whole genome shotgun sequence.
ACCESSION   DADVXB010000009 DADVXB010000000
VERSION     DADVXB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.009"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="KB902_000353"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="KB902_000353"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBB6807208.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="KB902_000354"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="KB902_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBB6807209.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="KB902_000355"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="KB902_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBB6807210.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="KB902_000356"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="KB902_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBB6807211.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="KB902_000357"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="KB902_000357"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBB6807212.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="KB902_000358"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="KB902_000358"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBB6807213.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="KB902_000359"
     CDS             complement(8054..8524)
                     /locus_tag="KB902_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBB6807214.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="KB902_000360"
     CDS             complement(8570..8995)
                     /locus_tag="KB902_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBB6807215.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="KB902_000361"
     CDS             complement(9062..9331)
                     /locus_tag="KB902_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBB6807216.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="KB902_000362"
     CDS             complement(9342..10937)
                     /locus_tag="KB902_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6807217.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="KB902_000363"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="KB902_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBB6807218.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /locus_tag="KB902_000364"
     CDS             complement(14490..15050)
                     /locus_tag="KB902_000364"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBB6807219.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="KB902_000365"
     CDS             15403..16377
                     /locus_tag="KB902_000365"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6807220.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="KB902_000366"
     CDS             16547..17947
                     /locus_tag="KB902_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBB6807221.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="KB902_000367"
     CDS             complement(18025..18747)
                     /locus_tag="KB902_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807222.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="KB902_000368"
     CDS             complement(18826..19332)
                     /locus_tag="KB902_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6807223.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="KB902_000369"
     CDS             19455..21254
                     /locus_tag="KB902_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBB6807224.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22896)
                     /locus_tag="KB902_000370"
     CDS             complement(21322..22896)
                     /locus_tag="KB902_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6807225.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="KB902_000371"
     CDS             complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="KB902_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBB6807226.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="KB902_000372"
     CDS             complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="KB902_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBB6807227.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24673..25311)
                     /locus_tag="KB902_000373"
     CDS             complement(24673..25311)
                     /locus_tag="KB902_000373"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBB6807228.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25312..25962)
                     /locus_tag="KB902_000374"
     CDS             complement(25312..25962)
                     /locus_tag="KB902_000374"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBB6807229.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="KB902_000375"
     CDS             complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="KB902_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBB6807230.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="KB902_000376"
     CDS             complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="KB902_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBB6807231.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29105..29845)
                     /locus_tag="KB902_000377"
     CDS             complement(29105..29845)
                     /locus_tag="KB902_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBB6807232.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="KB902_000378"
     CDS             complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="KB902_000378"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBB6807233.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31216..32154)
                     /locus_tag="KB902_000379"
     CDS             complement(31216..32154)
                     /locus_tag="KB902_000379"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBB6807234.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32147..32638)
                     /gene="def"
                     /locus_tag="KB902_000380"
     CDS             complement(32147..32638)
                     /gene="def"
                     /locus_tag="KB902_000380"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6807235.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32653..35061)
                     /gene="priA"
                     /locus_tag="KB902_000381"
     CDS             complement(32653..35061)
                     /gene="priA"
                     /locus_tag="KB902_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBB6807236.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35314..35619)
                     /locus_tag="KB902_000382"
     CDS             complement(35314..35619)
                     /locus_tag="KB902_000382"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6807237.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="KB902_000383"
     CDS             complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="KB902_000383"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBB6807238.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7988 c         6707 g        11988 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggtcgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag attgtgtagc
    22021 tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg ttgctgagct
    22081 ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt cgcgtgcttc
    22141 tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac gttgttgttc
    22201 acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt cagctttctt
    22261 gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca aatcagcttg
    22321 tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag ctaattcttt
    22381 tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt gtttttgttg
    22441 ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc gtccaatagc
    22501 atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg tgttgcttac
    22561 ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac gttcttgtaa
    22621 atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatctt gttttgctaa
    22681 taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat cgatttgtga
    22741 ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct gttgtatctg
    22801 agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca aggtcattga
    22861 acataccatt actgctgata ttaaactctt tttcactctt cattcctccg actggcttaa
    22921 tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt gtaccatagc
    22981 agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact tttaaaaatg
    23041 acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct agcatttctt
    23101 aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa ttattcatca
    23161 ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt caacagcagt
    23221 gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa tttaaaaatc
    23281 aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat actgaaaaat
    23341 tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca tacaattaaa
    23401 gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata gatagccccg
    23461 agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca acataataat
    23521 gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc ccctagcatt
    23581 cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag atagtacttc
    23641 attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat cgtcacaact
    23701 gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag cccataacta
    23761 tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt ccctccaaga
    23821 ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa ttgggtcacc
    23881 actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc gccattagcc
    23941 gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag taattcgatt
    24001 ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg cgacatgact
    24061 gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat gtcctgccaa
    24121 ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt cagcgtctga
    24181 ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt gttttgctgt
    24241 gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc ataagttgaa
    24301 aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc agagattgtt
    24361 ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg ctttccttca
    24421 ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac aataaccaag
    24481 gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg aattaattag
    24541 actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt gctcctctta
    24601 agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca aattttttta
    24661 tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg aaaaagaaaa
    24721 ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt ctacttcttt
    24781 attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag tcaagcagca
    24841 ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag gcaaataata
    24901 agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt tgaagcgagg
    24961 ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg tagctccaat
    25021 caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta actgtgtatc
    25081 tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa atacttcctt
    25141 ctgctcttcg ttcgacaatg aatcaaaatc gcccactgcc agatctactg ggtagcctgc
    25201 ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt tggacagcag
    25261 agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca tttagtctaa
    25321 tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga tatatgatcc
    25381 tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg gaacgattcc
    25441 gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag cgagttccgt
    25501 aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat tgacagtcat
    25561 gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg gtgttcctgg
    25621 attgataact actccagctt taactcctaa gctttttgtc atttgaagtg cccgatgaat
    25681 atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg caaatgctgg
    25741 aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt tagtaacagg
    25801 acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatt ggccatccat
    25861 tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt ctctttgtaa
    25921 attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt cctcctattt
    25981 tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt gtaagaattg
    26041 caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat gttttacttc
    26101 gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag aagcttctac
    26161 aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt caatcgagct
    26221 aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca catgacgtgt
    26281 tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat tcagttccgg
    26341 tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa agaccgatag
    26401 ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg gtacaatcac
    26461 cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg ggtcgtctga
    26521 caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca aggtaactag
    26581 aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga caatgattcc
    26641 aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca agatttccag
    26701 aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga caagcggcgt
    26761 gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc cgtttgcgta
    26821 tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg ccacctccgt
    26881 ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa acttctcaaa
    26941 gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa tgcaacaaat
    27001 caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact ttctgaggtg
    27061 ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct tgtgctactg
    27121 gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga agacgctgga
    27181 tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt cgttcctgcc
    27241 cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc ggaagtctca
    27301 tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct ttttgtatag
    27361 ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt gatgtaagtt
    27421 tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc tgatggtaca
    27481 gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg tgtaacaagc
    27541 caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac tgtttctggt
    27601 cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt atcttctgat
    27661 ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc ttctttttga
    27721 atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc ataactttta
    27781 ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag agtgacttcg
    27841 cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt accttcttcg
    27901 attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc ttttgcgagt
    27961 gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac ttctcctcgc
    28021 ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat agctaatagg
    28081 atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc ttcctcctct
    28141 ggcaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa tgaatcaggc
    28201 attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat cacatgaggc
    28261 tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc atcagacatt
    28321 tcctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa aatcacgttt
    28381 tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc atcttgaaaa
    28441 tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc cgtcaacatc
    28501 tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat acttcctctg
    28561 gcctgctcag gggacagata atgaacagat cccagcatcg tattcgtctg cgtgatcgat
    28621 gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc ttcattatcg
    28681 atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg agctaaagaa
    28741 atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac aggataatgt
    28801 gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag atactgcatg
    28861 ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag ttctgttgct
    28921 gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa gtcaaatcgt
    28981 aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa tacatttgcc
    29041 ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt tttgcccaac
    29101 tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta tccgctccgc
    29161 ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg ccttcttgat
    29221 tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct gaacataaca
    29281 gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact gttccaggca
    29341 tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt tcttcgctga
    29401 tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat tgcatgattt
    29461 tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg aaccagtcat
    29521 ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc tgttcttgtc
    29581 cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat tgggcgattt
    29641 tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt accgccatct
    29701 gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca gcaagcttga
    29761 gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt cgtcttccta
    29821 catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc aaacaacaaa
    29881 tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc tcttcgattg
    29941 atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg tgtctttcca
    30001 agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg ctataagtca
    30061 gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat tggatttttg
    30121 gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt cgccgaagca
    30181 gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct gcttcgaact
    30241 gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag acacctagac
    30301 gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa gcgaccactt
    30361 ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct ccgggtgctg
    30421 cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct acaagcatcg
    30481 aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa gctaaatgcc
    30541 cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg atctcttctt
    30601 cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact cgggcactag
    30661 catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat ccgatttgat
    30721 ccaccagtcg tttcgtcatc catagaggca ggctgatttt gacagaaagt ctttcgatag
    30781 gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc aagacaccat
    30841 ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc gcctcgttta
    30901 aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa agataaagaa
    30961 gcgtcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca acgtaaaatt
    31021 ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa cccacatctt
    31081 tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag taggcgccac
    31141 ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt ttcatttttt
    31201 tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac cgcttccgtt
    31261 aaggaaatca tgtacggcct gttttccttt accagctggc tgtaattcat tgatggctaa
    31321 gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga tgatcgtacc
    31381 aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc agcgtatgcc
    31441 ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt tgtcaatttc
    31501 ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg gcgaaaaagt
    31561 tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg gcaatgtttc
    31621 tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta catcatcttg
    31681 tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt ttttgatcat
    31741 ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat gaacaggcgc
    31801 acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta attttggtac
    31861 ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca catcaggcac
    31921 caattcaatg atttcttcca tttctggcga accggagatt ttctctggct gcagcacacg
    31981 gataccgtgc ttcagagccg cttcttttac cggtgtcggc gtaattactc gtttccgccc
    32041 aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt ctatcagccc
    32101 ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag tcatcaagat
    32161 gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt ttctcaatga
    32221 acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa tagccaaaag
    32281 ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact tcatctgctc
    32341 gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca aggctttcac
    32401 cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca tctacttcga
    32461 tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt ccgtcattcg
    32521 caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg attacatcga
    32581 ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga tagcgcataa
    32641 tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa aaagaccttg
    32701 tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa gattcggttc
    32761 atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca aaatcatgct
    32821 gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct gattggcaat
    32881 ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta ttttcacagt
    32941 aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct gataaaactg
    33001 ctcataattt tgttttttag ctaattctat ggcgtaatgt tgaggattga atgtttggat
    33061 cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg taagcaattg
    33121 gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag cattcaacac
    33181 cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg tccctaataa
    33241 tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc cttttcttcg
    33301 agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc ggagttcctc
    33361 ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac aattaggaca
    33421 gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac gtgtatccat
    33481 atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac agtccctaca
    33541 catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt cttttttgtc
    33601 taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc gatgattctg
    33661 aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg ctttggctcg
    33721 gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg attctaaaga
    33781 gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc aaattgctag
    33841 atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat gttcttcatc
    33901 gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg cgcctactac
    33961 tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac cttgggaaag
    34021 tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct cgaccatttg
    34081 cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg acaaaacatc
    34141 agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct ccagcaaaaa
    34201 gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat ttttttgttc
    34261 tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag ggtcgcgata
    34321 acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca agacagcagt
    34381 actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt cagataaaca
    34441 caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt cttcttcgat
    34501 ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat ttcgtgtatg
    34561 gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt gagaaaggct
    34621 gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca atacctgaac
    34681 ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca tcacactcgg
    34741 aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca tataatcagc
    34801 taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa taactgcctt
    34861 caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc cttggacatg
    34921 acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag ctgtttccat
    34981 ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta cgtccacaat
    35041 gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc ttatcaagcg
    35101 acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc ttctgccaaa
    35161 tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa agttcagaca
    35221 cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc tgggtttgct
    35281 tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt cacggatacg
    35341 tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt cttccatctt
    35401 caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg catcgatttc
    35461 ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag gctgtgcact
    35521 tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt ttgaatttac
    35581 acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc tcctttaaca
    35641 ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca ataatgtttt
    35701 tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg taaagagcca
    35761 tcatttcgat ttcttctttt gcaactttca ttcgttcttc gattacttca tctgcatctg
    35821 ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc aaaaagatga
    35881 atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca atctccaaga
    35941 aaacatcttt tccttcatcc aatgtcttgt tgatatatga caaaggagtt ccataataat
    36001 tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat tcaaactctt
    36061 ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt ttacgggtag
    36121 tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct tttcgtactg
    36181 tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc tctgacatga
    36241 cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt ttttctgcaa
    36301 ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc tgtaccaaga
    36361 ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa acagcttctc
    36421 atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg ccgtgtataa
    36481 gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga aaatagtttc
    36541 tcacattttt gcataaattt ggcttaata
//
LOCUS       DADVXB010000010        35584 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.010, whole genome shotgun sequence.
ACCESSION   DADVXB010000010 DADVXB010000000
VERSION     DADVXB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.010"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            13..843
                     /locus_tag="KB902_000384"
     CDS             13..843
                     /locus_tag="KB902_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBB6807239.1"
                     /translation="MIGLAILLSGCSKWIDRGESITAVGSSALQPLVETVAETYQAEN
                     PGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRVAVVGITPIV
                     NKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRSTFEKWVLDGE
                     TAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTDENVTTNKWT
                     IWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVERDWQGNIVKE
                     "
     gene            958..1878
                     /gene="pstC"
                     /locus_tag="KB902_000385"
     CDS             958..1878
                     /gene="pstC"
                     /locus_tag="KB902_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBB6807240.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1878..2762
                     /gene="pstA"
                     /locus_tag="KB902_000386"
     CDS             1878..2762
                     /gene="pstA"
                     /locus_tag="KB902_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBB6807241.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2777..3583
                     /gene="pstB"
                     /locus_tag="KB902_000387"
     CDS             2777..3583
                     /gene="pstB"
                     /locus_tag="KB902_000387"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6807242.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3599..4357
                     /locus_tag="KB902_000388"
     CDS             3599..4357
                     /locus_tag="KB902_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6807243.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4370..5047
                     /gene="phoU"
                     /locus_tag="KB902_000389"
     CDS             4370..5047
                     /gene="phoU"
                     /locus_tag="KB902_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBB6807244.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5269..6303
                     /locus_tag="KB902_000390"
     CDS             5269..6303
                     /locus_tag="KB902_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6807245.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            6300..7067
                     /locus_tag="KB902_000391"
     CDS             6300..7067
                     /locus_tag="KB902_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6807246.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            7167..8735
                     /gene="liaX"
                     /locus_tag="KB902_000392"
     CDS             7167..8735
                     /gene="liaX"
                     /locus_tag="KB902_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBB6807247.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            8911..9219
                     /locus_tag="KB902_000393"
     CDS             8911..9219
                     /locus_tag="KB902_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBB6807248.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            9219..9569
                     /locus_tag="KB902_000394"
     CDS             9219..9569
                     /locus_tag="KB902_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBB6807249.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            9735..10673
                     /locus_tag="KB902_000395"
     CDS             9735..10673
                     /locus_tag="KB902_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBB6807250.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10688..11518
                     /locus_tag="KB902_000396"
     CDS             10688..11518
                     /locus_tag="KB902_000396"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6807251.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            11562..12587
                     /locus_tag="KB902_000397"
     CDS             11562..12587
                     /locus_tag="KB902_000397"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6807252.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12602..13540
                     /gene="galU"
                     /locus_tag="KB902_000398"
     CDS             12602..13540
                     /gene="galU"
                     /locus_tag="KB902_000398"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6807253.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            13665..14114
                     /locus_tag="KB902_000399"
     CDS             13665..14114
                     /locus_tag="KB902_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBB6807254.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            14107..14721
                     /locus_tag="KB902_000400"
     CDS             14107..14721
                     /locus_tag="KB902_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6807255.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(14784..15887)
                     /locus_tag="KB902_000401"
     CDS             complement(14784..15887)
                     /locus_tag="KB902_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6807256.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            16097..17098
                     /gene="ccpA"
                     /locus_tag="KB902_000402"
     CDS             16097..17098
                     /gene="ccpA"
                     /locus_tag="KB902_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBB6807257.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            17452..17847
                     /locus_tag="KB902_000403"
     CDS             17452..17847
                     /locus_tag="KB902_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807258.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            17844..19100
                     /locus_tag="KB902_000404"
     CDS             17844..19100
                     /locus_tag="KB902_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBB6807259.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            19112..19435
                     /locus_tag="KB902_000405"
     CDS             19112..19435
                     /locus_tag="KB902_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807260.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            19428..19694
                     /locus_tag="KB902_000406"
     CDS             19428..19694
                     /locus_tag="KB902_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807261.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(19857..22202)
                     /locus_tag="KB902_000407"
     CDS             complement(19857..22202)
                     /locus_tag="KB902_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6807262.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            22481..23383
                     /locus_tag="KB902_000408"
     CDS             22481..23383
                     /locus_tag="KB902_000408"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBB6807263.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            23594..25369
                     /locus_tag="KB902_000409"
     CDS             23594..25369
                     /locus_tag="KB902_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBB6807264.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(25678..27264)
                     /locus_tag="KB902_000410"
     CDS             complement(25678..27264)
                     /locus_tag="KB902_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBB6807265.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            27515..27739
                     /locus_tag="KB902_000411"
     CDS             27515..27739
                     /locus_tag="KB902_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBB6807266.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27881..29632
                     /locus_tag="KB902_000412"
     CDS             27881..29632
                     /locus_tag="KB902_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807267.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            29632..31416
                     /locus_tag="KB902_000413"
     CDS             29632..31416
                     /locus_tag="KB902_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807268.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31751..32602
                     /locus_tag="KB902_000414"
     CDS             31751..32602
                     /locus_tag="KB902_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6807269.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            32699..34585
                     /locus_tag="KB902_000415"
     CDS             32699..34585
                     /locus_tag="KB902_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6807270.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34626..35528)
                     /locus_tag="KB902_000416"
     CDS             complement(34626..35528)
                     /locus_tag="KB902_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6807271.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
BASE COUNT        11475 a         6348 c         7531 g        10230 t
ORIGIN      
        1 ttattcttac caataatagg attagctatt cttttatcag gctgttcaaa gtggattgat
       61 cgaggagaat ccattactgc agttggctct tctgccttac agcctttagt agaaacggtt
      121 gctgaaacct accaggcaga aaatcctgga aaattcatca atgtacaagg gggcggaagc
      181 ggaactgggt tgtctcaagt acagtcagga gcagtcgata tcggaaattc tgatttgttc
      241 gcggaagaaa aatcagggat tgatgcttcg gcattagtcg atcatcgagt agcagttgtt
      301 ggaatcactc ctattgtgaa caaggatatt ggcgtaaaag atatcagtat ggaaaacctg
      361 aaaaaattat ttacgggcga gatcaaaaac tggagtgaag tcggtgggaa agatcagcca
      421 gtagttatat tgaaccgtgc atcaggaagc gggacccgta gtacgtttga aaaatgggta
      481 ttggacggag aaacagctgt tcaggcacaa gaacaagatt caagcggaat ggtgcgccaa
      541 atcgttgcgg acacacccgg agcaatcagc tatgttgctt tttcttacgt ttccgatgat
      601 gtggatacgt tgaacgttaa cggtgtggaa ccaacagatg aaaatgtgac aacgaacaaa
      661 tggacgattt gggcatatga gcatatgtac acaagagacc atccaaaaaa actgacaaaa
      721 gaatttttag actatatctt atctgatgaa gtacaagata atattgtcgg agagctaggc
      781 tatatccctg tttcacatat gaaagttgaa cgtgattggc aaggaaacat tgttaaagag
      841 taatctttac acaaaattta caaacttagc taaactttta catgttatta aaaccaaatt
      901 gatgttcaat ttgtacactg agtgagtatg ttaaacctga ttaaggggga gtcatctgtg
      961 gaagatgtga aaaaagtatt attaacaaaa tcaaaacgtt caaaaatgga acagcgcgga
     1021 aaattcatta gttttttgtg tatcgcgctg atcgtgttgg ttgtattatc tattttttat
     1081 tttgtcgcta gtaaaggatt ggccaccttt tttactgata agatcaatgt atttgatttt
     1141 ctgtttggta cagattggaa tccaagccaa ataggagcaa atgggaaacc catggtaggg
     1201 gcattgccta tgatcacagg ttcatttatt gtgacctttt tatctgctat tgttgccaca
     1261 ccatttgcta ttggagcagc agtgttcatg acggagattt ctcctaaaaa cggaacgaag
     1321 atcttgcaac cggtcatcga gctacttgta ggtattccgt ctgtcgttta cggatttatc
     1381 ggtttatctg ttatcgtgcc ttttgtcaga agtatctttg gcgggacagg gttcggtatc
     1441 ttagctggta catttgtgtt attcgttatg atcttaccga ctgtcacaac gatgactgtg
     1501 gatgcattaa aggcagtgcc gcgacactat cgggaagctt cattagcgct aggtgccaca
     1561 agatggcaaa caatctacaa agtggtgctg cgagcagcag tgcccggaat tttaacagca
     1621 gtcgtttttg gtatggctcg tgcgtttggc gaagccttag ctatccaaat ggttattggt
     1681 aatgcggcat taatgccaac aggacttact actcctgctt ctacattgac gtccatcttg
     1741 acaatgggaa tcggaaatac aatcatggga acagttgaaa ataatgtgtt atggtcatta
     1801 gcgctgatct tgctattgat gtcattattc tttaatatcg tgatccgtat gattgggaag
     1861 aaaggagagc tgaaataatg aacgcaaaac gctcagataa aattgctaca ggtgttctat
     1921 atgtggtttc agggatcatc gtattgatct tagcagcttt attactttat atcttagttc
     1981 gaggaatacc gcacatttca tggtcattct tgactgaacc ttccaaagcc taccaagaag
     2041 gcggtgggat cgggattcaa ttatttaact cgatttattt gcttttgatt accatgatca
     2101 tcagttttcc tatctcttta ggtgcgggta tctacctttc ggaatatgcc ggaaaaaact
     2161 ggctgacaga cgtgatccgt acgtctatcg aaatcttgag ctctttgcct tctgttgttg
     2221 tcggtttatt cggtttcttg gttttcgtta ttcaattcca gtatggtttc tcaatcattt
     2281 ctggtgcatt agctttgacc gtattcaact tgcctctttt gactcgaacg gtcgaggaat
     2341 ctttacaagc ggtccattac acacaacgag aagctggatt ggcgttaggt ttgtcacgct
     2401 gggaaacagt gataaaagtg gttgttccag aagcgacacc aggaattttg actggtgtga
     2461 tcctaagttc aggaagaatt tttggtgaag ctgccgcatt gatttataca gctggtcaaa
     2521 gcgcgccagc attagatttt acgaactgga atccattaag tgtttctagt ccgatcagca
     2581 ttttccgcca agctgaaaca ctggctgtcc atatttggaa aatcaacaca gaaggtacga
     2641 tgcctgatgg tgtttctgtt tcggctggcg cttctgccgt gttgatcatt gctgttttac
     2701 tgttcaactt cggcgctcgt gcgattggca aacgattata ccgaaaaatg acttcagcct
     2761 aaggagaaga agtaaaatga aaaaatataa ttggaatgaa acaaatgtca ttaccatgcc
     2821 aaaagataag gaagttgcat tatatacgaa tgatctgcat gtttggtatg gcgacaatga
     2881 agcaatcaag ggagtggatc tagaattcga aaaaaataag atcactgcat tgattggtcc
     2941 ctctggctgc ggaaaatcca cgtatcttcg ttctttgaat cgtatgaatg atgggattgc
     3001 taatacgaaa attactggaa agattatgta taaagacgtg gatatcaatg cgcctcaagt
     3061 ggatgtttat gaaatgcgta aacggatcgg catggtgttc caacgcccca acccttttag
     3121 caaatcgatt tatgacaata taacttttgc tttgaaacag catggtgaaa aaaacaaaaa
     3181 gaaattagat gaaatcgttg aaacaagctt gaaacaagca gctttgtggg atcaagtaaa
     3241 agatagcttg gataaaagtg ccttggcttt atctggcgga caacagcaac gtttgtgtat
     3301 cgctcgtgca atcgcgatga aacccgatat cttgctgtta gacgagccgg caagtgcctt
     3361 ggatcctatt tcgacaggaa cggttgaaga aacacttgta aacttgaaag aagactacac
     3421 gatcattatc gtgacgcata atatgcaaca agcagctcgt atcagcgact atactgcctt
     3481 tttctatcta ggaaaagtaa tggaatatga caaaacaaac aagatattta ccagaccaaa
     3541 aattcaggca accgaagatt atgtgtccgg tcattttggt taagacggag gcctcaacat
     3601 gacaaaagaa attatctcat ccaaagatct tcatctgtat tatggaaaga aagaagcact
     3661 aaagggaatt gatctaagtt tcaatcaagg tgaaatcaca gcgatgatcg gtccttctgg
     3721 ttgcgggaaa tctacctatc tacgttcgtt gaatcgaatg aacgatctga ttccaaatgt
     3781 aacgatcacc ggaagtgttt tatataaaga caaagacatc tatggtccga aaacagatgt
     3841 tgttgaacta agaaaagaaa tcggcatggt gttccaacag ccaaatccat ttcctttttc
     3901 tatttatgaa aatgtcatct atggattgaa gttaaaaggt gaaaaagata aaaaagtcct
     3961 tgatcaagta gtggaagaaa gtctgaaggc agcgtccgtt tgggaggatg tgaaagataa
     4021 actgcataaa agtgccttgt ctttatccgg tgggcagcag cagcgtgtat gtatcgcacg
     4081 tgttttggca gtgaatcccg aaatcatctt attggacgaa ccaacaagtg cacttgaccc
     4141 tgtttctact gggaaaatcg aaagtatgct gttagaatta agagagcggt atacgatgat
     4201 catcgtgacc cataatatgt ctcaagcttc acgtatttca gataagacgg cattcttttt
     4261 agatggtcac ttgatcgaat acaacgatac gaagaagata ttcatgaatc cagaaaaaca
     4321 agagacagaa gattatattt caggtcgatt tggataagga ggaaacggaa tgctacgtac
     4381 acaatttgaa gaagaattgc tgaatctcca taatcagttc tacgaaatgg ggatgatggt
     4441 gagcagcgct gtgcacaagt cagttcgtgc atacatcaaa cacgataaaa tcttagctca
     4501 agaagttatc gaaaacgata taaatatcaa taatatggaa acgcgtttgg agaagaaaag
     4561 ttttgaaatg attgcattac aacagccagt tacaactgac ttgcgtatga ttatcacggt
     4621 catgaaagct agctctgatt tagaacgtat ggccgatcat gcggtgtccg ttgctaaatc
     4681 cacaatccgc gtaaaaggac agacgagaat accggaaatc gaaaaagaga tctccgatat
     4741 gtccgattac gtgaaaaaaa tggtggacaa cgtcctagtt gcgtatgtca aaacagacga
     4801 aaaagatgcg cgtacaatcg ccaatatgga tcaaagagtc aatgactatt tcaatcgaat
     4861 ctataatgca accatcaaaa acatgcaaga aaatcctgaa acagtcatca gtggcacaga
     4921 ctatttgaat gttgccagct atctagaacg aatcggagac tatgtgacaa acatctgtga
     4981 atggatcgtc tacttggcta cagggaaaat cactgaatta aatacgaacc acaatgagat
     5041 tttctaaact gaagttgtga ttctgctgtt tatttaggaa aagaggttgt gaaatcagcg
     5101 ttttgtcctg agtattagag aaacaaacgg taaaatagtt cctcatattt tgccgttttt
     5161 tgagctaata ccgaaggtca gctgattgaa caccgtttat tctggaaaag ggtttgtgac
     5221 aaaacatgtc acaaaccctt ttcattattc caatagaaag gataaagaat gcaaaaaaag
     5281 attagcatca tcatcactct attttttatt tgtatacttg cttcatggtt tattcagcgt
     5341 caagctgctc tatatgacgt acctgtcatc gagatcgaaa gagtgagaat agaagaggat
     5401 caacaattga ttacaggaag attgatgaat acggaccaaa aaggagaagt gatttcttta
     5461 acggctcctt atcaaaaaaa tcaaatcgaa acagcaaata taacaacaag acaaatctat
     5521 cttgtccaaa tgcatggaga tgaatggcaa ctagtagcaa aaaaaaatga tggctggctt
     5581 tttttcttta caagtgtctt cattggcacc atgttgctta ttggtggaaa acagggcgta
     5641 tttgctttag gaagtctcat catcaacatc gttttacttt tacttttgtt gctcctcttt
     5701 accaaaacag aaggtatttc tctcttaaat atagcaatct tatttgtcgt tatagggata
     5761 atcgttagta tattggcgtt agacggatgg aatagaagca gtataatcaa aatttcggct
     5821 gcagttacaa gtgttttttt agcatttttt atttgtcttt tgacaatgaa tcattggaaa
     5881 gatcaaggac tgcgctatga agaactgaat tatctgacac gaccgtatcg ttctgttttt
     5941 ctttccagcg tgctgattgg gacagctgga gggacactcg ataccgtgat cacagtcatt
     6001 gcgacattag aagaattgac caagcaacaa ccgaaaatat cagcgaaaca gttatggctt
     6061 tcaggaaggc aagtgggccg agatgtgatt ggttcgatgg ctaatatcct tttattcgtc
     6121 tatatcagcg gagcgattcc atcgcttctg ttatatttag gaaatcaatg gtctttcaaa
     6181 gaaacggtag aacgacattt atcattagaa cttttacgcg tcattgctgg cagcttagga
     6241 atagtattat caatccccat cgcggtcctc ttttttctcg ctgtaaggag gttaaaaaaa
     6301 tgaatgtact tattatactt gttgggattt ttgcaatcag tgtgctattt gtcggtggta
     6361 cgcaaggtat gtatattctt ttaggattat tcattaattt aggaatcttt ttcctattat
     6421 tattcggcta tcatcagaag tggccgatat tggtattgtc gattataggg ttcctattga
     6481 tcgctgtggt tatcttattt tttatcaatg gttataatct gaaaatgcga gccgcttttg
     6541 ccagtatact gatctttttg ttttgtttcc tactattgat tcctatcact gattttttag
     6601 cgatccaagg ctttacttcg atagaactag aagaactatc tggcttagat aagacgttag
     6661 caattgattt tagactactt acgaggtcgt tgcttctgat cagtcttagc ggagctgttt
     6721 tagatgcgag tgtagcgatt tctagtggaa cattcgaagt atatcaggca aatccgcaaa
     6781 tgtcttttaa ccaattgcgc catgctagct ttgccattgc taaaaaaata ttggcatcaa
     6841 cagtgatgac gcttcttttt gcgtttatgg ggagttcttt agcgttgatt ctttggttta
     6901 ttgacttaga catttctttt cagcaaataa tcaatgaaaa atcatttgtc ttggaatata
     6961 cgatggctat tcttaccaca ctggccgcac tacttgtcct gcccttaact tgcgtgacta
     7021 cagcatatct ctttacaaaa aagaaagaac atctcaagat ggagtaaaag ttacaactta
     7081 agtcctatga catttttact gaatcagtgc ataatatgga tgtaaggaaa agcttgcaaa
     7141 caattttgct taaggaggca atttccatga aagaaagaga acgtatttta gacttagtga
     7201 aaaaaggaat cctttcgact gaagaaggct tagatttatt agaaagcatg gcaactgaaa
     7261 aagacgaaaa acaaatcaaa aaagaagcag acaaggtaac tgctagtcat aaagaaaaag
     7321 atcaggcaag tcaattgatc gatgaacttg aaaacggtga agaaaaaatt tctgagccag
     7381 ttgatccaaa agaaaaagaa agacaagatc aagaaaactt agaaaagatc ttagatgaac
     7441 tagcaactga agcgaataaa acttcggcgc gtctagacga agtaaatgct caattcgctg
     7501 acaataaggc agcacgtaat gagaaacagg aagcattgat gcagctgaat acaaaagaag
     7561 aattaggcga gttgacagaa gaagaattag cacagcgtca aacgttagaa gcagaaatca
     7621 aagagttaga agcaaccggc gatacactat tagaagaaca attgaagctg gaagcagaat
     7681 taaaagatat ccgcaagaat caatggtctg agaaaaaaga aacatttacg gataagtttg
     7741 aattgccaga tgattggaaa gatcaagcga cagatacgct gaatcaagta ggcgaaaaaa
     7801 tgtcagaagc tggatcacag ttaggcaaat tcttgaagaa aacattccaa actgtttcag
     7861 aaacagtaaa tgataacatg gaatggaaag atgtcagctt acgcgtccct ggaattgcga
     7921 caacgaaatt tgaacacgaa ttttattatg aagctcctgc agcaagtatc cttgatatca
     7981 aggcagcaaa cggaaacgtg acgttaaaaa cgtgggacag tgatgatgtg aaagtggaag
     8041 ccaagatcaa actttacgga aaaatgggtg ctgaaccatt tgaagcattc tctgaacgga
     8101 gccagatcga ggtcaatgaa gatcatatct ccttccaaat tccaaataag cgtgtgcgtg
     8161 cagaccttgt tttctacttg cctaaacgag tatacgacca tgcagctatc aaacttctaa
     8221 atggcaacat catgattgag acattggaag ctaaagatat ttatacaaaa tctacgaatg
     8281 ggaacatcat cgtgaaccaa ttaactgcaa cgatgctgga agtagaaggt gtaaacggca
     8341 atatcgatat tcgaaacggg aacatcttag attctattat agaaacagta aacggtacag
     8401 tgacatttgg tgccacacca gaaaaccttt ctgtgtcttt agtaaatggt gatgtacgtc
     8461 ttacgattaa agaagataat ttgaaaaaag tagaagcaag ttcagtgaac gggaatgtca
     8521 aagttgcttt accagatagc atcggtttgg aaggacacgc taaaacaagt cttggaagca
     8581 ttaacagccg tctgtccaat tacgaagtag ttcgtgagaa aaaagaacgg acaaaccaaa
     8641 tgttgcaatt ccgtcgtgtt tcagatgatg agatcgcaca agtgcagctt tcaacgacaa
     8701 caggaagtat ctatttaaaa gatacagata aataaagagg ttgtgaaaga gatgttcagc
     8761 cttgagcaat aagaagcgat tttttaaaat agcttcccct attttaaaaa aatgtgcctt
     8821 attgccgata ggctatctct tgaacaccga ttaagaagaa ggttgtcaca acgattttct
     8881 tcatttaaaa tagtagaaca gaggtgagac atgatgaaaa aaaagttgac aaaatccaat
     8941 aaaaatgttg ttttgacagg tactttagca gggattgggg aatatatcgg gattgatccc
     9001 actgttatcc gtgtgcttta tgtattctta agcttagttg cttttggaag tccaatcatt
     9061 ttatacattt tattagcttt gattatccca tctgcgcgtt ctgcacgaac aaactatgga
     9121 cataacaatg catattatga aaaaaacaat tatcgtgaac aaacaaaaaa acgcaaagaa
     9181 gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt cagcgtattt
     9241 tggttaatac gttaacattc atatcgttgg ctgttctttt tcctgcgatg gtccatgtga
     9301 gcagtatttg gacggccgtc cttgccagct tcgtattatc tgtgttgaac atgtttgtca
     9361 aaccgatttt gacgatcctg tccctgccct ttacattagt cacattggga ttgtttacgt
     9421 ttgttatcaa tgcagcgatt cttaaaatga cttccttttt tgtaggagca gaacatttta
     9481 gtttttcttc atttggtgca gcgttattcg tagctatctt gatgtcactt gtcaatgtaa
     9541 ttgttagtga acataacagc agaaaataaa aaaagctgtg ccgagatctc ggcgcagctt
     9601 ttttgtttag aataaagaat gcgttttcta ttacattggt aattaaataa aaacgttttt
     9661 tttaattggt agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa
     9721 atgaggtagc atgaatgtca gaagttgtaa aagttagcca attagtaaaa aaattatctt
     9781 tggaaatcgt cacaggcgac gagaaaagtt tagaccgcgt catcgtgact ggggacatct
     9841 cacgcccagg actagagttg accggttatt ttaattatta ttcccataat cgtttacagc
     9901 tatttggcag taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca
     9961 ttatgagaag attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattgccgg
    10021 ctccggaaga aatgatccaa gcagccaatg aaaatgggat agctgtgctg cgttcgccta
    10081 tctcaacgtc ccggctgcta ggtgaattat ctagttattt agatggacgc ttagcccctc
    10141 gaacaagtgt ccacggtgtg ttagtcgatg tctacggatt aggtgtacta attcaagggg
    10201 acagtgggat agggaaaagt gaaacggcgt tggaactgat taagcgcgga catcgattga
    10261 tcgcagacga tcgagtagat gtctatcagc aagatgaact gacggtaatc ggagaacctc
    10321 ctaaaatcct ggaacatctg attgagattc gagggatcgg tatcatagat gtaatgaatc
    10381 ttttcggtgc gagtgcggta cgaggctcta tgcaagtcca gttagctgtt tatctagaag
    10441 catgggcgaa agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg
    10501 cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca
    10561 tcattgaagt agccgcaatg aatttccgcg cacgtacaat gggctttgac gcaacgaaaa
    10621 catttgaaga aagattaagt cgcttgattg aagaaaactc aggcaatgac tagcaaggag
    10681 tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag cttgtaggaa ttcctatcta
    10741 ctggtatgca ttgattatcg tatcaggaat cattattgcc atgtggctca gcagcagaga
    10801 agctgttcgg gtaggattaa aagcagatga cgtgacagat tttatgttgt ggggattgcc
    10861 gatttccatt attggtgccc gcttgtatta tgttttattc gatcttcccc aatatatagc
    10921 tgatccaatc cagatattca atatccgttc aggaggatta gcgatttacg ggggattgat
    10981 tgcaggtgca atcacactgt acttttttac caaatatcat tttatttctt tgtggacctt
    11041 tttagatatc gctgcaccaa gcgtattatt ggcgcaggca atcggacgat ggggaaattt
    11101 catgaaccac gaagcgtatg gtccagacac gacacgaagt ttcttagaaa gtctgcattt
    11161 accgcaattc atcattgata acatgtatat cgaaggaatc tatcgacaac caacctttct
    11221 ttatgaatca ctttggagtt tgattggatt tattctgctt ttggttttgc ggaagaaacc
    11281 acatcttttg aaaaaaggag aagtcctttt atgttatcta atgtggtata gtttcggacg
    11341 tttctttatc gaagggttac gcacagacag cctttacttt ttaggtgtga tccgcatttc
    11401 tcaattattg tctgctgttt tatttgtcgg cacattgatt ctgtttattt ggcgtagaaa
    11461 aaaaggaagt ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatttgatt
    11521 ttcagagcgt taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg
    11581 ttttaggacc aggctcttgg gggactgctt tagcacaagt cctcgctgaa aacggacatg
    11641 acgttcggat ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacca
    11701 atcaacgtta tttaccagat catcatctac ccgattccat ccgagcattc accgatatgg
    11761 aagatgcagt aaaagatgca gatgcggtac tattcgttat cccgacgaaa gcgatacgtt
    11821 ctgttgcaaa agaactagtt gccaaattga atacgaagcc agtgatcatc cacgcaagta
    11881 agggattaga acagggaacg cataaaagaa tctctgaaat cttgttagag gaaatcccga
    11941 cagaaaaaag aaaagctgtt gctgttcttt ctgggccaag ccatgcggaa gaagtagcaa
    12001 agcatgacat tacgacgatc acagcggcaa gcacaaatgt aaaagcagca aaatatgtac
    12061 aagagctgtt catgaaccat tattttcgaa tctataccaa ccctgatgtg attggtgtag
    12121 agatgggagc agctttgaaa aatattattg ccattggagc tggtgctatt cacggcttag
    12181 ggtttggcga taatgcaaaa gcggcaatca tgacgcgcgg attagctgag atcagccgtt
    12241 taggtgtagc aatgggtgcc aacccgctga cctttattgg cttaagcgga gtaggtgatc
    12301 tagtcgttac ttgcacaagt gttcattcca gaaactggcg cgcaggcaac ttgttaggac
    12361 aaggtcagcc tctagaagag gtgctagcca atatgggaat ggttgttgaa ggtgtgaata
    12421 ctactcaagc agcgatggaa ctagcccaaa tgatggaaat cgaaatgccc atcactcaaa
    12481 caatctatga agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt
    12541 tacgtgatgg gaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta
    12601 tatgaaagta aaaaaagcag ttattccagc agcaggatta ggaacaagat ttttaccagc
    12661 aacaaaggcg atggcaaagg aaatgttgcc aatcgtggac aaaccaacga tccaattcat
    12721 cgttgaagaa gcgttgaaat caggaatcga agacatcttg atcgttacag gaaaagctaa
    12781 acgaccaatc gaagatcact ttgattcaaa tatcgaatta gaaacaaacc taagtgaaaa
    12841 aggaaaaacc gaattattga aattagtaga agaaacgaca gatgtcaatt tgcatttcat
    12901 ccgtcaatct catccaaagg ggttaggaca cgccgttctt caagcaagag cctttattgg
    12961 aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg gaagacgaag taccattgac
    13021 acagcaattg atcgatgact atgagcgtac acacgcttct acgattgccg ttatgcaagt
    13081 tcctcacgat gaaacttcaa aatacggaat catcaaccca ggggaagtac tggaagatgg
    13141 gttatacaat gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt
    13201 agctattatt gggcgttact tattgactcc agaaatcttt gatgtattat cagaacaaca
    13261 accaggcgct ggaaatgaga tccaactaac tgacgcaatc gatacgttga ataaaacaca
    13321 acgcgtattt gcccgtaaat tcacaggtaa acgttatgac gttggtgaca aatttggttt
    13381 tatgaaaaca agtattgaat atggtctgac acatccagaa gtaggggcac ctttgcgtga
    13441 atacatcatg tctttaggta aaacattaga agcagaagga agcaagatca atcataatcc
    13501 aaaaggaata acagaaatca aagaagaaaa gaaaaaataa tctttttttc taacgagctt
    13561 cagctgctaa ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa
    13621 aatgctatcc ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa
    13681 ttgcaggatt gatcgcagca atcgcctttg cgatacttgt cgttttcatc gttcgcgtat
    13741 tgttgcaagt ttccaaaact ttagaaaaag tagaccagac tgtcgcagaa gcaaatacga
    13801 caattgagat cgtcacacaa gacgtagatc ttttatctag acaagtagaa ggcttgctag
    13861 tcaaaagtaa tgagctgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt
    13921 tcacagcagt tgctgattta agtgaaagtg tatcggaact taatcattct agtaaaaaca
    13981 tcgtgacgaa agtcggcgga atcggaaaaa cgacagctaa agcgactgtt gccggaaaag
    14041 tcggtggaac agcgatgaaa tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14101 ataagaatgg ctaaaaaagg tggattttta ttaggtgcag tagttggagg tacagccgca
    14161 gcaatcgccg cattattgtt agcacccaaa tctggtaaag aacttcggga tgaattggct
    14221 gctcaagcag atgatttgat ggacatggct tcagattaca cagatatggc aaaagaaaaa
    14281 tcatctgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggg
    14341 gatctagcag gcaatgttaa gcagaaggta agtgaatcag cagaggaagc aggaagcgaa
    14401 tcagatgata tcttgttaaa cctcaaagaa caatcagctg atttatctaa tcgtttcaaa
    14461 aaaacagcag aagatctgaa aaagccagca gacgaattag gtagtattgc taaagatact
    14521 tcagaagata tcatgatcga tgtaaaagat gctgcagata aagcaggaga gacggtcaat
    14581 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgtt gaaaatggca
    14641 aaagaagatg caaaagaaga tgcaaaagaa gctaaaaaag aaatgaaaga tacaatgaca
    14701 gattcgacta ccaatcacta agattactca tttctagaat aaaaaaggtg agagcggacc
    14761 agctctcacc ttttttattt tcattactct aaaacaagta attcttttgg tgtagtcgtg
    14821 aatggcacac aaccatcact tgtcacatac acacaatctt cgatacgtac ccctactttt
    14881 tcaggaatat agattcctgg ttcaagagag aagcacatcc cttcttcaat cactaagtcg
    14941 tttccttcta caagagaagg gaattcgtgg acggttgttc cgattccgtg acctaaacgg
    15001 tgattgaaat attcgccgta gccatagctg ttgatcacgt ttcgtgcgat ttgatcaagt
    15061 tcacctgctg tcacacctgg gcgaactgcc tcttgtgcgg caagctgtgc ttcaagagtg
    15121 atgttataga ttttttcttg gaattcagtt ggtttttgat aagcaactgt acgagtagca
    15181 tcactgcaat agccattcca aataacgcca agatcgaata acactagttc atttggtgaa
    15241 accttcgtgc ttcctggtgt accatgaggg cttgcagcat ttgctcctgc aaggactaat
    15301 gtgtcgaaag acatttgtga aacaccttgt ttttttaatt ggtattcgat ttctgcgata
    15361 attgcttgtt cagttacgcc ttcttttact gttttgaagc caatttcaaa ggcaacatcg
    15421 gcccatttac cagcttcgat cagtttgtct ttttcttcta ccgttttgat cagttgcaga
    15481 cgctggataa tagaagttag atcggtgtaa gaatctgtac ctgtcaagat atcagagata
    15541 gcatcgaagc gatcgacagt cagagcattc ttttcaatac ctacattacc aggttgccca
    15601 tagcgtgcgc gaagctcttt tccgatgatc tcccaaggat tttcgctgtc taagtagcca
    15661 cgtacatcgt acgcccagct gctgttttga gcatcttcaa cttccagagc aggagtgaaa
    15721 aggaaaggat cttgttccag agggataaaa agagctagta cacgctcgtg aggatcactt
    15781 tcatatccgg aaaagtaagc gatgtggcca gggtcgctga tataagccaa ttctaattgg
    15841 tgttgtgcca tccattgacg tagttcattg atttttacgt tattcatttg gcaacctact
    15901 ttctaaatta attttgtatt caataattgt accactgatt gattaaaaga ccaacgttct
    15961 taaaactgaa aaaagtaaaa attttcatga aaacagagat aaaacggttg caattgttga
    16021 gattatttga tatcctattt tagaaatgta agacgtattt tcagaaaaca tataaaatat
    16081 gaataggaga acacaaatgg aaaagcaaac aatcactatc tatgatgtag cgagagaggc
    16141 aaatgtttcg atggctactg tttcacgtgt cgtaaatggc aatccaaacg tcaaaccagc
    16201 aacaagaaaa aaagtcttgg aagttatcga tcgcttggat tatcgtccaa atgcagtcgc
    16261 acgtggcttg gcaagtaaga aaacaacaac agttggggta atcattcctg atgtcagcaa
    16321 tatgttcttt gcctctttag cacgtggtat cgacgatgtg gcaacaatgt acaaatacaa
    16381 tatcatctta gcaaactcag atggcaacga tcaaaaagaa gtcaatgtat tgaataattt
    16441 attggctaag caagtggacg gcgtgatctt tatgggtcac catatcacag acgaaatccg
    16501 tggagaattt tcacgttcaa aaacgcctgt tgtactagct ggttccattg atccagatga
    16561 acaagtaggt agcgtaaaca ttgattatgt atcagcaaca aaagatgcag taaataaatt
    16621 agcaaaaagc ggcaataaaa aaatcgcttt tgtcagcggt gcgctgattg atcctatcaa
    16681 tggtcaaaac cgtctaaaag gctataaaga agcattaagc gaaaacaatc taccatatag
    16741 cgaaggattg atttttgagg cacaatacaa ctttaaagat ggtctgtctc tagttgaccg
    16801 gatccataat agcggtgcaa cagctgtcta tgtttcagac gatgaattag ccattggtat
    16861 cttggatggt ttattagacc gcggcgtaaa agtaccagaa gaattcgaaa tcatcacaag
    16921 caacaattct ttactgacag aagtagctcg tcctcgtttg acaagtatca cacaaccatt
    16981 atacgattta ggagcggtat ccatgcgcct attgacgaaa atgatgaata aagaagaagt
    17041 cgaagaaaaa acgattatct tgccttatgg aatcgaagaa aaaggatcaa ctaaataata
    17101 aaagatcaat catttaaagg ttgttcccaa agtggtcaac ttctggaaca acctttatac
    17161 gagaaaaggg gttatgacaa aattttgtca taaccccttt ttttgtgact ttaaaaaaaa
    17221 gagagaatgg cggaaacaaa ccttacgtcc atcgtatacg acacaatctg tgcgtagatg
    17281 ctacattttg ttcactacta tcaaaattac tttaaaatga aaacgtgata aaaaagaaag
    17341 tagaaaagta gaaaagtaac tctaaaaaat ccaaaaaaat ccaggctcga ttgcgtactt
    17401 atcttaaagg agaaacaatc catcatacat aacccgaaag gagacttcta tttgcctaag
    17461 aaaagacgaa agaccatagt catcattttg accattctta ctataggaat cggaggaaaa
    17521 ttttacatgg acaaaagaga agcgcaaaaa cagcaagatt tactcgcagt agaaaaacag
    17581 tccgtcaaag ttctgaaaaa tacctttgcg gatatcaaag aagtgaaaat cgaacaattt
    17641 gagaaaaacg acatgacagg aatctatgaa gcattgataa cgatgaccaa tacagaagga
    17701 aaagccgttt attttgatta tagctttaca aaagaaagca atgagataga tggctatggt
    17761 gttgaaaatg aagaagtaca aaaagaaggg attacggttg atgagattat agttatctat
    17821 acagatggga gtgaggaaaa agtatgacaa ttactgataa gcagtataaa ggaataagta
    17881 ataaagtata ttggctagat ccaaaacatc ctcaatatag taaaagttac aaagaaggcg
    17941 ccattaaaaa ctttggagaa acaaaattcc aaatcctaaa aatcaaaaac tccttcgacg
    18001 gcatgcaggc gatggctgta gcgccaatca agaacggtaa agtggatatt tctcaagtag
    18061 tgattgcttt tgcaggaacg aacttaagcg attggaaaga tttggaaacg gatgcaagaa
    18121 gtgttatgaa tctctatggg aatagaccag gagcaagttt ttctgaaaaa gcaacaacaa
    18181 acaagatttt atccgttagt ggattgaaaa cagcggggca aatcaattca gcgattgcat
    18241 ttgctaatga agtaaaaaag gaatatggag aagctgctat ttctactacc ggccattcat
    18301 taggtggatt cttagcatta tatgtagcag cagagaaaca atggaaaaat gtcggcttca
    18361 acgggccgga cccgtatgat ctcttatcac cagaagcaaa aaaatgggtg gaagaaaatc
    18421 ccggtatgct caccaattac cgaaatcacg ccgattttat cggtaatttt ggtggtaatg
    18481 gcacaggtgc tgaagttcgg atcagtatgg aaacagcata cttgaatctg cttgcttccc
    18541 acagtttaac ctcttggaag tttgatgaaa atggaaagct gattattcct gaaaatgaaa
    18601 acaatgttaa agctcgaaaa caacagaaag aaaaccaagc gacccagttg ttttcctatc
    18661 agttgcaaga actgaacaac atacgtaaaa aactacgatt aagtggcggc cggctgacag
    18721 ttaatgaaca aatttactta gatgacacac aagctaggtt agtggtggaa aagttatcgg
    18781 taaaaatgaa aagcgctatg gaagaagtta tccgcatcaa ccaaagagga atttttgagc
    18841 tagagaaaaa atggcaagaa ggcttgcggc aagcacgtgt tgtcgcccct tcgttgactg
    18901 aacaggaaat catagaagca ttagctagtg tgggcgccac aaaagagaac ttagtcgatt
    18961 ctgcgaaaga agtctatctg ctacgaatca ataaggcaag acgtatgggg gaggcctttg
    19021 atacattggc gaaggagatc caagacaaaa tcaatgaaat cgtggcacga gatcgagaat
    19081 tagcacagca attcaattaa aggagaagta gatgaaacta gaagaattgg aaagagatta
    19141 tcgaagtgaa cgaagacaat tagaagctca agaagatgaa ttgatccact ttaagaatca
    19201 aggattacga ttgatggagc aagaggagca gcgactgcat catgtattaa agaacttagc
    19261 tttagataat gagcctctgt ttcaagcaag acgaagttat tcgaattatc aggagcatta
    19321 tcaacaagcc ctacaagtag aacgacgaaa actctatcag cagcaagacg aactagaacg
    19381 ttcctatcgt caaaaaatca gacaaataac tatggagaaa tcatcttatg aatgaatttt
    19441 taatgcaatt actaaaagaa ttagagaaaa atctacatcg atcaaatgta cgttcagttg
    19501 gtatggggat atctcagcaa acttgggcag aaaaacgatt gacagatcaa aaccaccaaa
    19561 tgactgcaga agaagctact caagaatttt ctaaccgaca tgcacactta aaagaatcag
    19621 taaaagggca atttgcagaa aaactaaccg aattattcca aagacaagaa aagaaattaa
    19681 aacagtttcg ttagtaaagt tatatagaaa aattttgtga aaatggtttt tcacattttt
    19741 acataaattt gtcttaatat cgtagatgta agcttttgaa caccatttat tcggaaaaag
    19801 ggagctgtga caagattttt gtcgcagctc cctttaattc tgattaatct attagatcaa
    19861 tcatctttat cgtctgattc tttggtctct ggattcgctc tagcataagc tgaagcggtg
    19921 ttccagtaat ctgtatagtt ttcatcagta ccgccaacgc cgaatttaaa ggcgcttttc
    19981 ttcggaccat tttttgccca aagtgattcc actgtttttc ctggcgtttg gatagatttt
    20041 ttattgacag taacttttcc agctgtttgt cctgtgaacc cagatacttt tttcttcatc
    20101 acatcggatg ataagtcaaa tttctcatca gtgccgaaaa tctcagggtt tgcttggtaa
    20161 gcttgattga ttagattggc aagataatta gccgaacgta ttcttgcttg gctgtccatt
    20221 ccagtattgt catcgtgtcc tgcccaacta ctgatagtga tagatggagt tgagacgatc
    20281 agccatgaat ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcatttcct
    20341 agatttccgt ttaagcttga gatgacatct ttgaatggtg tagtgatttt ttcattgatc
    20401 acactacgca tcatgtcatt catgatcgat gccgttgctt cggaataaat acggacagaa
    20461 ttactttcat gtttataaat cacattacct gcattatctg tgatggaatc aatgatatag
    20521 ccttcttcgt agactccacc atttgctaag gcctggaatc catttgtctg ttgaagcgtc
    20581 gttacatcta ctgtccctaa aggagccgat tcaacgcccc aattatcatt tgctgggtag
    20641 ttcatcttcg ccaagtagtg ctcgtaagcg tattgtttcg atccaccgga attcaacaca
    20701 tcttgatata agtgataagc tgggatattg ttggaccatt ccagtgactc acggacggtt
    20761 tggaaggtgt tcgacccttc attggtcgca ttgacgattt tctcaccagc attttttcct
    20821 tcttgccaag tcgttgcata atctgataca cgggattctg atccgacaag tcccatatcg
    20881 attgcaggac cgtaaacaag aaccggtttg atggatgaac cagcttgacg ttctgtatca
    20941 aaggcgtggt tattttgatt ctggctgtaa ttccgaccac ccacgaagcc atagatacgt
    21001 ccggttctgt tatccatcaa tacatttcca gtctccactt ggctaccagc accatcatct
    21061 aacatgtagc cataattttc tacgccggtt tgcaatgcag catagatatc tttatcaatc
    21121 gtcgaatgga tcgtatatcc tttgttttgg atcgtttgct gtgctttttg ataataagct
    21181 tcactgaccg atgaatctga catatcagca ttatcttttt ctgccaattg ttgtgcaata
    21241 atccttgttg cttcgttcat cacggtataa tacaagaatt ctctgtcagt ctgttccgcg
    21301 atttgttgtg ggagaaagtc ttttgtaaga tcataggctt tcgcttcttc gtattgttct
    21361 ttcgtaattt gtccttcacg gtacatactg aataaaacaa aatcttttct ggcaagaccg
    21421 gcagaaagat cttcttttag cgcgcctgta ttcgtgtatg gactatacgt gatagggctt
    21481 tgaggcaaac cagcgatata agcagcttgc ggcagagtca catcctttgc atctacacca
    21541 aagattcctc tagcagcttc ctggactcca gcaatatttt gccccttatt attccgacca
    21601 aatggtgaga cattcaaata cgtagtaatg atctcatctt ttgaaaagtg tttttctact
    21661 tgtgcagaaa gaacgatctc gtttgcttta cgtttgaatg ttgtttcatc ggttaggatc
    21721 tgttgtttga ctaattgctg tgtcaaagtg gatcctccag acgagccgat gccagtcgct
    21781 tctgaaacta gtgctcgtaa aacagcttta gggacataac cttggtgttt atcgaagtat
    21841 tcatcttctg tactgataat cgcggttttc aataaaggcg aaatcttatc agatgaaata
    21901 gtcgtccgca tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc
    21961 tttgacgttt ccgtaatgtt tcctagttct gtctgcagtt cttttttagt cggcaattgt
    22021 gtgtcttcga caagataggc aaagtagcca gcacctattc cgatacctag agctgcgaac
    22081 aacaaaagaa gaacagtaat aaaaacagtc aatgattgaa acactctaaa aataatctta
    22141 ggaacaaacc atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc
    22201 aaaagggtca cctcaactaa tggttttatt tcgctaatta tagcaaataa taggacaaaa
    22261 aaacagacaa ggctgttttt gacaggaatt tctttttcga atgagataaa acgtgaggaa
    22321 atgatctttt ttatgaaaga gttcttaagc ttttctttag ggaaagtttc agttactatg
    22381 gagaacaggg caaagaaaaa caaactattt tctttgtaca tcatcttatc aatatacagg
    22441 aattgttcga aacaattgcc tttcaaggag gaatccatcc atgttattag gctcacacgt
    22501 cagcatgagc ggaaagaaaa tgctgttagg cgcggcagaa gaagcagcca gttacggatc
    22561 ttcgaccttt atgatctata caggcgctcc tcaaaatact agaagaaaag ctatcgaaga
    22621 gatgaatatt gatgccggaa aagcatttat ggcagaaaac ggactaacaa atatcgtcgt
    22681 tcatgcgcct tatatcatta atttgggaaa tacgatcaaa ccagaaatgt ttccatttgc
    22741 tgtacaattt ctgagagaag agattgtccg tgcggaagct ttaggtgcta ctcaaatcac
    22801 ccttcaccca ggcgctcatg taggagcagg ggcagaagct gggattgcta gaattattga
    22861 ggggttgaat gaagttttga caaaagaaca gacggcacag atcgctttgg agacgatggc
    22921 agggaaaggt acggaaatcg gtcgaacatt tgaggaatta gcgcaaatca tcgatggagt
    22981 aaaattgaat gaaaaattat ccgttacttt tgatacatgt catacgaatg atgccggata
    23041 taatataaaa gaagattttt caggtgtaat ggaagagttt gataaggtca tcggattaga
    23101 tcggcttaaa gtactgcata tcaatgattc taaaaatcct caaggttctc ataaagatcg
    23161 gcatgccaat atcggttttg gaacaattgg atttgacaca ttgaacaaaa tcgtccatga
    23221 tccaatgttt gacaacattt cgaaaatatt agaaacccca tatgtcggta aagataaaaa
    23281 gaaagcttac gcaccatatg gaaaagaaat ttccatgttc aaagcgcaag cattcgatcc
    23341 cgaagtgttc cctgagttat tagcagaaga agtcacactt taagttttct acctgacagc
    23401 aacaaaaaag gattgggcag tctgccttgt ccttttttgt ttaagaaaca aaggagtgct
    23461 ttttgcattc gttttcgcca tgctcctttt gccccctctt tttaaattca gacaaacagg
    23521 gtatactgat agaaaagtaa aaaacgaaaa gtttcacaaa caagtagcaa aacgtgattg
    23581 aaaggacgaa aagatgctga acattttaaa ccccttgatc gaccaactaa aaaagaaaca
    23641 tacatacttt attcttggca tagccgtatt atttacaatt attcggttgt atttatatag
    23701 taaagcaatc tatggaacag atatgtcggc gacctatgat gatcagctgc tgattcacta
    23761 tgctcaaaat attttggatg gtaaatggct aggggagtac acgactacga cactttcaaa
    23821 agggatttcc tacagcttgt ttttagtact tgcacataaa ctgcatcttt cttatgcagt
    23881 tttattcggc atgttcagta ttcttgccag tatattggtt gcactagcgt ttaaaccaat
    23941 cgtgaagaac aagtatcttc ttttaagtat ctatttttat tttttgtttt ctccgattag
    24001 ttttacacat gaatattcca ctcgaacata tcgtaatgct ctcgtgatcc cgactgttga
    24061 gatcattatc gcttgtttac tagctattta ttaccgcaaa tataattcca gcaaaaaatt
    24121 gctgccgtgg tttttagggc tagctgtttc ttttcctttc ttttggttca ttcgcgaaga
    24181 ttccatctgg cttcttcctt ttactgtagt cgcgttaggc atcagtttcg ttcagatctt
    24241 gctaggacaa gacttttctt tcaaagaagc aaagaagtta aaagaacgac catttctcct
    24301 ttcgaaacaa gaatggctga aactttcatt gtttttactc cctctagtcg gtttctccat
    24361 cgtctatcag tggatcgaat ataaaaacga gacaacatat ggtattgcag ccatcaatga
    24421 ccgttcgagt ggcgaatttg gacgtttgat gaaacagctg atccgaatag atgacgaaac
    24481 aaacttaaat aaagaaaaca gtgagatatg ggtctcgcat gctgcattaa ataaagcttt
    24541 agacgcatct cctacatttc atactgtttc tactcgtatt gacgaattgt atacgactca
    24601 tgcgtggacc caaggcggaa aagtaaaaga attaccagga gatatcattt tttgggcatt
    24661 gcgagatgtg gtaagcgaat ctggttatta ccaaaacaat gcaaaagaaa ccaatgattt
    24721 ttggaaaaaa gtcaatcaag aattagaaga agcctatcaa aagggaacta tcaaaaagaa
    24781 aaaagaattc tatctgatgg gatcagggga tggaaagacg atgaatgatc tgccaatcgt
    24841 atttgatttt ctgaaatcag gatatgctta tgcatggcga tacaaagatt tccatcaagg
    24901 ggggaattat agttttggga cgcaagaaca agtcgaacag gcacaagaat tattgaatct
    24961 tccactaatg gataattgga tcgatagcag tgatccgaga acacctgatt tccagttgac
    25021 aaaaacagca aaagtcgcga atgtcatgat aaaaatttac caagttctgg ccattcccgt
    25081 gctgattgct tcaatagcag ggatattact tatgatacta ggaaccgtat ttgcaaaagc
    25141 tgatcgtgcc tattatagtt cctctttgat tgtagtcatc ggattaatac tgacacaatt
    25201 ggtttttctt ttcggtgtct cgtggttttg ttcttatgcg ccagaaaaaa aggattattt
    25261 tttaagtgtc tacactggcg caggcgtgcc attaacgcaa ttcatcgcag taacaagcat
    25321 gctagttttt agtaaattga atctgaaaaa agctttatct tccaaataaa aagggaactg
    25381 tgacaaaagt cttgtcgcag ttcctttttc cgaataaacg gtgctcaaaa gcttgcatct
    25441 gcggtaataa gctcaaccaa acgtaaaata tgaggaacta tttttgtttg gctgttctta
    25501 ttacttgatg cagggcagct ttttcacaac ctctgataca cggtgttcca gaagtaactt
    25561 cttcggaaat aagccgaaat ttcacaaaaa tttgaaaagc aattttctta aattccttct
    25621 tatttcttga agctgcccac ttctgtcaca acctcctttg tgtaaaagaa tcagtttcta
    25681 ttcgatttct tctatcgttt cttgcaaacg ctgttcatat tttttgtttc ctttatataa
    25741 atcaccaatc gtccatgcca acaggagaag gacaagaaca atgattacat aggcgatttg
    25801 atcagccaat gctagttgag ctgaggtggc ttgctcgccg aagaaacttt cgatttgacc
    25861 tggtaatcct cgtaagttca agtaagtcag actaatcaca gagaaccagc caagaagttt
    25921 tacaacaaat gaatttttga atcggctccc catctccgct tggctattgg tcatcatcag
    25981 taaaggaatc atcgagaatg gcaatgcaaa agccagaaaa acttgggatt cattcatcaa
    26041 gttattcaaa gcggtatgtt cttcgatcgt tccttttgta cttgtaaaca aaacacaaat
    26101 caatacagga atcacagaaa gcaatcgtgt gactagtctt cttagccaaa tcgggatacg
    26161 catatggatg aatccttcca tgatgacttg accggtcaac gtaccagtaa tagtagagtt
    26221 ctggccagaa gcaagaagtg ctacagcaaa taaagtagac aagataccag attttgctac
    26281 agcaatcaag ataccattgc tcatagctga tggatcagat aaagcttcat acagaccaaa
    26341 aaaggaagga tcttggacag aaccggtttt gaatacagcg acacccatga tcaatagcag
    26401 tgcattgact aaaaaagcca ttgacaactg gatattagag tcccaagtag aaaagcgtac
    26461 cgcttgtgct acatcttctt cgtcttggtg atcgatcttc cgagtttgag aaactgctga
    26521 atgaagatat aagttatgcg gcatgactgt tgcaccaata atccctaacg ctccagtcag
    26581 cggagtttca ccacctatga caggtgagtc tgagaatgta tgactgttag ggataaagcc
    26641 agcaaataaa ctgtgccaat cagggttaga caagccaact tgatagacga aaacgaataa
    26701 aatgacgaaa atcaagcaga caaccaaagc ttcgatttta cgaaacccga cttttgtcag
    26761 caataaaagg acgaaaacat ctaacacagt gataaatacg gcaattacca atggaatatc
    26821 aaaaagtaag tagagggcga ttgctgcacc aatgacttct gcgatgtctg ttgccataat
    26881 ggctaattca gtcaagatcc ataaaatgac acccaatgtc ttacttgtcc gtgctcggat
    26941 tgcttgggcc aaatccattt gggtcacgat tcctaatttt gctgccatat actgtaaaag
    27001 catagcaatt agactagaca tcaaaataac tgacatcaat aaatattgga aattttgtcc
    27061 accagtgatc gaagtggacc agttacctgg atccatataa ccaactgcta ctaatgcacc
    27121 tggtccagag taagcaagaa gtgttttaaa aaaacttttt ccctttggta catccactgt
    27181 tccatttact tcagctaaag ataaaccatt tgtatgttca ataagtcgat gcttatgaaa
    27241 ttgtttgttg gattgattat tcaagaaaaa accacctttc ctatttatct acgattacat
    27301 tctacacctc agaaagaaaa aattaaagaa aaagattcgg tatgcctaat tttttttcgt
    27361 ggcgtgtctt gctggttaat gaaagaaatt ttgttcttct ctaaaaaaac cactattttt
    27421 tgcatgaaac taaagaatac gcctttcttt tttcaataaa ctttagtaaa ataaatcatt
    27481 gagagcaatt cggaaataga aaggagagat ttatatggta tcaacaggta ttgtcgtact
    27541 tattgctatt attgctttgc taatcggcgc agtaggtggc tttttcctag cgcgtaaata
    27601 tatgaaagac tatttagaaa aaaatcctcc cgttaatgag gacatgttgc gatcaatgat
    27661 gatgtcaatg gggcaaaaac catctgagaa gaaaattcgc cagatgatgc agcaaatgaa
    27721 gaaccaaggg aaaaaatagg ttctgaccca aagacttttt gcgggctgat tttttcagtc
    27781 cgttttttat ttcgtaattt gttagactat tcagactatt cagcaaaaaa gacaaggaca
    27841 gacaatccta tgctcttgat aaagacaaag gaggagtaaa atgtcgattt ttagaaaatt
    27901 aggttggttt tttcgtcagg aaaagaaaca ttatttaatt gggattttct ccctattcgc
    27961 agtggccttg gtacagttag ttcctccaaa agtgattggg atcatcattg atgagatcgc
    28021 cgataagaat ttatcaataa agatcatttc ttggtggatc ttactattga tccttgcagc
    28081 tttcttacaa tatctttttc gttatatctg gcggacgaat atttggggaa gtgcagctcg
    28141 gttggagaaa gaacttcggc agcagctatt caaacatttt acagaaatgg acaatctctt
    28201 ttaccaaaaa tatcggactg gagatttgat ggctcatgca acgaatgatt tgaatgcaat
    28261 ccagaatgta gcaggagctg gaatcttgac ctttgcagat tcagtgatta cgggcggaac
    28321 aacgatcatt gcgatgattt tgtttattga ttggcgctta acactgattg cgctgattcc
    28381 tctgcctttg ctagccgtta cttcacgagt gctggggtca aaactccacg atgcttttcg
    28441 tgattcgcaa gaagcttttt ctagtatcaa tgataagaca caagaaagta tcactgggat
    28501 caaagtcatt aaaacatttg gacaagaaaa agaagatctc gcggattttg aagaaaagat
    28561 tgaagatgca attattaaaa acaaacgagt caatttttta gactccttat ttgatccatt
    28621 cattaccttg attatcggtc tgtcttatgt tgcaacaatt attttaggtg gaaagtatgt
    28681 cttggaaggc acgatctcga ttgggcagat ggtctcattt attagttata tcggtatgct
    28741 tgtttggccg atgtttgcga ttggccgatt gttcaacgta ttggaaagag gaaatgcttc
    28801 ttatgatcgc gttaatgaac ttttgcatga aaagacgcat atcgtggaac aactgggtgc
    28861 agtgcagacc ccggcaaaag gcgagctgaa tgtagctatt tcctctttta actatccgaa
    28921 agaagaatca ccagcattag aacaaatcaa atttgcgatc caagaaggag aaacattagg
    28981 tattgttggg aaaactggtg cgggaaaaac gacaatcatc aaattactga tgcgtgaata
    29041 cgatgattat caagggaaaa tccaatttgg cggacgttcg atcaaagaat attcattgaa
    29101 tgctttatta ggatcaatcg gttatgtgcc tcaggatcac ttcctgtttt cgatgaccat
    29161 tcgagataat atccgttttt ctaatccaaa actttcagaa gaagaagtag agcatgcggc
    29221 ttctttagca tttatcaaca atgaaatcaa ggaattgcca aaaggttatg ataccttagt
    29281 tggagaacgt ggagtctctt tatctggcgg acagaaacaa aggatttcga ttgctcgagc
    29341 attgatcaaa aatcctgaat tgctgatctt agatgatgca ctttctgcag tagatgccaa
    29401 aacagaagaa gctatcttgc ataatttaaa agaaataaga aaagagaaaa caaccatcat
    29461 tgcagctcac cgtttaagca gcgtgatgca tgcaaaagaa atcattgttg tcgatcaagg
    29521 gaaaatcatt gaacgaggaa cccaccacga gctgcttgca ttaggtggct ggtatgaacg
    29581 aatgtgggaa aaacagcaat tagaagcgaa gatagaagga ggcgaggcct gatggatgaa
    29641 aattatcaat cggaatggac aaaatcgatt ccacttaaag aacagaagaa gatcatcaaa
    29701 cgactgatga agttcgccaa accttttaga agaacgttca tcgttgctat cttatttgcg
    29761 tttgccctgt ctgtgatcaa tgtcctattg ccaaggatca tccaaacttt tatggatgat
    29821 catctggcta aacagtcagc tacgacacaa gttattttgt tttttgctgg tgtgtacttg
    29881 tttggagtca tagtcaaaag tatcatttgg tttttccaat ggtatttgta ttccatggct
    29941 tcattgaaga cctatcagta tgttcgggta agattatttg aaaagctgca tacactaggt
    30001 atgcgttatt ttgaccagac accggcagga tcgaccgttt ctcgagtgac gaatgacaca
    30061 gaaacgctat ttgaattttg gtatgtcttt ttgatggtat tgactgggat ctttgcagtc
    30121 gtttcttctt tcgttgccat gtttcaaatc aatggagaaa ttgccttgtg gactttggtg
    30181 ttcttgccga ttttaggaat cgtcatctgg tattaccaga aattcagttc tcgtatttac
    30241 cgaaatatgc gggaaaaatt aagtcagctg aacacgaaat tgaatgaatc gatttccggc
    30301 atgcgtatta tccagcagtt tcgccaagaa gctcgtttag ctaaagaatt tgaacaagtg
    30361 aacaacgagt atttagacac gcgctatgcg atgatcaaaa cgaattcgat tctgttaagt
    30421 ccgatcatca attttctcta tgcattggcg attgcgttgg cgttgacttt gtttgggatc
    30481 gatgcgttgc attctcccgt agaagttgga ctgatctatg catttacgac ctatgtccag
    30541 ggatttttta atccaatgtc tcaaatgatg gactttttga gcacctttac agatgggatg
    30601 gttgccggta gtcgtatttt gaaaatcatg gatacagaag aatatgcacc gcaacaaaat
    30661 cctggagcag atcaagcgat tacttcaggt aagatcgagt ttcgcaatgt aagcttttct
    30721 tatgatggag agcacaatgt attgaacaat atctcttttg tcgctaatcc gggtgagacc
    30781 gttgcattag tggggcacac cggaagcgga aaaagctcga tcatcaacgt attgatgcgg
    30841 ttttacgaat tttatgaagg ccaaatcttg attgatgatc atgacattcg agaatatcca
    30901 atggaagagt tacgtaagaa aatgggattg gtcttgcaag atgccttctt gttttatgga
    30961 gatattgcag gaaatatccg gatgatgaat ccagctatca cagacgaaca gattcgccat
    31021 gcagctgagt ttgttcaagc aaacaagttc atcgatgaat taccaaaagg atatcactca
    31081 aaagtgatcg aacacggtgc cagctattct agtggacaac gacagctgat cacttttgcg
    31141 cgaacaatcg tgacagatcc taaaatacta gtattggatg aagcaacagc aaatatcgat
    31201 actgaaaccg aaggattgat ccaagaagga ttggcaaaaa tgcgacaagg acggacaacg
    31261 attgcgattg cccatcggct gtccacgatt cgggatgcag aattgatttt agttttagac
    31321 aaaggtcata tagtagagcg tgggaatcat gaaacacttc tagcgcaaaa tggtttgtat
    31381 gcagatatgt acaaactgca aagcagtggt gtgtaaaaag aggttgtgac agtagcatag
    31441 tagcattttg tcctaagcgc tagagtgaaa ataaaacaga gcttcccaga ttcttcatct
    31501 gtgagcgtta gtggcgtagt cacccgattt aaaaaagacg acgacagcta gtcaaaagtg
    31561 cctaatagcc actaagaaag cgttgacaaa agcgtttgct ttcgataata taaagaaaac
    31621 gatacaactt ggatagtgat tgcctgatgc aagctaaacc tgatgagtct cccatggttc
    31681 catggacggc tttttgggtt tttctttttg ttttgaatac agccctatat atcatggaaa
    31741 ggagcaaaac atgctgattg agaaagtact gaataacaac gtcgtaataa ccagggatga
    31801 aagaaatcag gaaatgatcg tgatgggaaa aggtttggca ttcaaaaaga aagtgggtga
    31861 cccgattttt gactcatgca tcgacaaaaa atttcagttg acaaatgacg ggctttcaca
    31921 acagttccaa gaattggcac aagcgattcc tcttgagtac ttagaaattt cttgtgaaat
    31981 cattgaatat acaaaagagg ctctacaagt ccagttgaat gattctgtgt atattgcatt
    32041 gacggatcat ttgtatacgg ctatcgaacg tcacaaaatg ggaatatttg taccaaatgt
    32101 attgctgtat gatatcaaac aactatttcc taaagagtat gccatcggga aaaaaacagt
    32161 gaagaaaatc tcggataaat accacatcaa gttatcagaa gatgaagccg gatttatcgc
    32221 attgcattta gtcaatgcac aaggcattca aagccaacaa aacaatacct acctgtttac
    32281 tataacaata caggatattc taaatatcgt ccgctattac tataagatta catttgatga
    32341 agattcagtc catttttttc gattcgtcac acacttacgt ttttttctga cacgcgtcct
    32401 agatggagaa aaatcagaag tgggagaagt ttctgaggaa ttgtttcagg ttattcaaaa
    32461 aaaatataag gatacgtttg gttgcgttga gaaaatagca gactttttag ccgagacgtt
    32521 caactaccag atgtccacgg acgaaaaaat gtatttaacg atccatactg cgcgtttagt
    32581 gcatgagaat cgttgtaaat aaataaaaaa aggaggataa attaacaaga acgtatgaaa
    32641 taagggtagt gacattcagt tggctaaacc ttccactaat atattggagg gaatagaaat
    32701 gggaaaatac caagaattag cgagaaaaat cgtagaaaat gtcggtggga aggaaaatat
    32761 caatggtttg acacattgta tcacaaggct tcgtttcaaa ttaaaaaacg aagaaaaagc
    32821 aaatgatgag atcttgaaaa atatggacgg tattgtaacg gtaatgcgag cgggagggca
    32881 gtatcaagtt gtcatcggga atcatgtgcc agtcgtgttt gaagaggtta taaaagcagg
    32941 aaaccttact tttgatgagg ctgtttcaac agaaaaaatg agaccgtttg atatgcttat
    33001 tgatggaata tcgggctgtt tccaaccatt ccttgctatc ttagctgctg gcgggatgat
    33061 tcgtggactg acagcattcc ttgtcttctt aggcgcgttt gaccgcggtt ctggcacatt
    33121 tgttatgttt gataatatcg gtgattctgt attccaattt atgcctgtta ttatcggttt
    33181 aacagctgcc cgtaaattta aagtaaatga attcgtaggg atgttgcttg gcgcagcatt
    33241 aatgaatcct agcttgtcgc tggaagcttt gagtggtgca gcagaagcac cactaacgac
    33301 catattttct ggcactattt ttgaagcacc tatttatcaa acagtattcg gcattccctg
    33361 gattgcgcgt aactacgctt cttctgtcat tcccattatc tttattgtgt tgttagctag
    33421 ccaaattcag aaaccaatta aaaagttagt acctgagatg atcgcgaatt tcttcgttcc
    33481 attcttcacc gttcttatta caatgccttt aggtttttta ctcgttggac cagtattcac
    33541 attcgcaact gatattttaa tggctggatt tgaaacactt ttagcacttt cgccagttat
    33601 ttatggagca atcgtaggct tcttctggca aattctggtg atgtttggtc tccattgggc
    33661 aatcgtacca atgggattga tgcaattttc tgtgaatggt tggcaaaata ttatgacacc
    33721 tgttgcagta gtgtcttttg gacaaactgc agcacttacc gcactctact ttaagcttag
    33781 aaatccaaaa gacaaagcaa ttgcaatacc agccattgtt tctggtattg tggggattac
    33841 agagccagct atttatgggt ttacattacc acgtaaaaaa atatttattt ttacttgtgt
    33901 cggtggtgcg ttagggggcg cgtatagtgg gttaatgaat ttaacttctt ggaatcaagg
    33961 tggactaggc atctttacaa ttcccaacta tattagacca gatggtgatt taacagatgt
    34021 gattaatgta ttgattggga tcgccattgc gatggtggta tcctttgcgc tgactttttt
    34081 cttttggaag gaggaagcag gtgaaacaga tgacagacag aaaagatcag gtaaagaaat
    34141 tgtaaaaaca ccgatacaag gacaaatcgc tccactgaaa gcagcaaagg atgcagcttt
    34201 tgcacaagga acactaggtc gaggaatctt gatctaccct gaaaaaggag aagtacgtgc
    34261 cccttttgac ggaacagtca tgaccctgtt ccccacgaaa catgcaatcg gaatggtttc
    34321 tgaaacaggt ctggaattgc tgattcatgt cggattggat actgttcagt tggaagggaa
    34381 atattttgaa agcttggtgc agcaaggaga aagagtgaaa caaggcgatc tgttgctccg
    34441 cttcgacaaa aagaaaatcg aaaaggaagg atacagttta gaaacacctg taatcgtcac
    34501 caattacatg gattatttgg atattttgga aaatcaaggg gagacggtcg ggccagacga
    34561 tgcacttatc accgcactga cctgaacggt taggtgaaag aatggaatag acttaactat
    34621 tctttttagt ccacttcttt attttcaaaa ttgaaaggct ctttcatgat ggctgagctg
    34681 atagggcgtt tatcaaattt ttgtcctaca gaaattagat ggactaaatt ctgttgataa
    34741 ttttctgcaa aaacacaact atataacacg tctagaagat aacaaatcga tgtattgatc
    34801 gtaaaattac caatttttga atacagtcgt tcgcgtgtcg taagtcgcaa agcggctgta
    34861 ctcattgagg atagcgttga atcaccgata ctggtcaacg ctaaaattgg aacatgattt
    34921 tgtttcaata tttctgcggt acgaaggatc acattgtttt cacccgtata agaaatcaga
    34981 atcccgcaca tatcactcgt gcaattgtac gcttcataga acgattcacc aaaagtggtg
    35041 acaatcgtga catccatttt gatgcgcttc attttcagca tgaaatcttg agaaatcaaa
    35101 gtattcgagt tactggcgaa aatcacgatt ttttttgctt gaagcattag ttgtttggct
    35161 ttttgcagtt ggtcatgatg aatgagagaa agtgtatctt gaatcgtcat ctgttctaaa
    35221 gaagccattt tatttgcgat cgtcataata ccgtctgtgg tggaaaaagg aagattcgca
    35281 tctacgtctt gaaaattccc ttcaagatag gctgtttcag ctaaaaaagc attacgaaaa
    35341 ctgacccagc catcaaaacc catttttttt gctacacgga tgagtgtgga cgggtggaca
    35401 taacatcgct cagcaatctc ttggatggtc atttcgccaa gtgctggaga atcgcttaag
    35461 agaaactgaa tcacttcatt ttctgaagga gaaaaggaga tttctttgat tttttcacgt
    35521 aataacatgt agataccttc ttctagtttt tttacgtaaa ttataacttt tttgaaaatg
    35581 attt
//
LOCUS       DADVXB010000011        34370 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.011, whole genome shotgun sequence.
ACCESSION   DADVXB010000011 DADVXB010000000
VERSION     DADVXB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.011"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..422
                     /locus_tag="KB902_000417"
     CDS             <1..422
                     /locus_tag="KB902_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBB6807272.1"
                     /translation="AIYTNEDALVIKKEQGFTGTETKSLFLKDKKDNNYVYLTFTTKQ
                     TDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFGYEKQIPIIIDEELLSNEKLVF
                     APGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN"
     gene            459..1469
                     /locus_tag="KB902_000418"
     CDS             459..1469
                     /locus_tag="KB902_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBB6807273.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(1584..2297)
                     /locus_tag="KB902_000419"
     CDS             complement(1584..2297)
                     /locus_tag="KB902_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807274.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(2487..3077)
                     /locus_tag="KB902_000420"
     CDS             complement(2487..3077)
                     /locus_tag="KB902_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBB6807275.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            3561..3788
                     /locus_tag="KB902_000421"
     CDS             3561..3788
                     /locus_tag="KB902_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBB6807276.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            3804..4970
                     /locus_tag="KB902_000422"
     CDS             3804..4970
                     /locus_tag="KB902_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBB6807277.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            5204..6247
                     /gene="hrcA"
                     /locus_tag="KB902_000423"
     CDS             5204..6247
                     /gene="hrcA"
                     /locus_tag="KB902_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBB6807278.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            6341..6904
                     /gene="grpE"
                     /locus_tag="KB902_000424"
     CDS             6341..6904
                     /gene="grpE"
                     /locus_tag="KB902_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBB6807279.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            6955..8784
                     /gene="dnaK"
                     /locus_tag="KB902_000425"
     CDS             6955..8784
                     /gene="dnaK"
                     /locus_tag="KB902_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBB6807280.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            8935..10101
                     /gene="dnaJ"
                     /locus_tag="KB902_000426"
     CDS             8935..10101
                     /gene="dnaJ"
                     /locus_tag="KB902_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBB6807281.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(10183..10848)
                     /locus_tag="KB902_000427"
     CDS             complement(10183..10848)
                     /locus_tag="KB902_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807282.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            10824..10997
                     /locus_tag="KB902_000428"
     CDS             10824..10997
                     /locus_tag="KB902_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807283.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(11042..11779)
                     /locus_tag="KB902_000429"
     CDS             complement(11042..11779)
                     /locus_tag="KB902_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6807284.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(11781..13283)
                     /locus_tag="KB902_000430"
     CDS             complement(11781..13283)
                     /locus_tag="KB902_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBB6807285.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13542..15536
                     /gene="uvrB"
                     /locus_tag="KB902_000431"
     CDS             13542..15536
                     /gene="uvrB"
                     /locus_tag="KB902_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBB6807286.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            15546..18362
                     /gene="uvrA"
                     /locus_tag="KB902_000432"
     CDS             15546..18362
                     /gene="uvrA"
                     /locus_tag="KB902_000432"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBB6807287.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            18625..19890
                     /locus_tag="KB902_000433"
     CDS             18625..19890
                     /locus_tag="KB902_000433"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBB6807288.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            19894..20625
                     /locus_tag="KB902_000434"
     CDS             19894..20625
                     /locus_tag="KB902_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBB6807289.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            20760..21644
                     /gene="rapZ"
                     /locus_tag="KB902_000435"
     CDS             20760..21644
                     /gene="rapZ"
                     /locus_tag="KB902_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBB6807290.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            21641..22639
                     /locus_tag="KB902_000436"
     CDS             21641..22639
                     /locus_tag="KB902_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBB6807291.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            22673..23608
                     /gene="whiA"
                     /locus_tag="KB902_000437"
     CDS             22673..23608
                     /gene="whiA"
                     /locus_tag="KB902_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBB6807292.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            24176..24832
                     /locus_tag="KB902_000438"
     CDS             24176..24832
                     /locus_tag="KB902_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807293.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            25011..25576
                     /locus_tag="KB902_000439"
                     /pseudo
     CDS             25011..25576
                     /locus_tag="KB902_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26275..26796)
                     /locus_tag="KB902_000440"
     CDS             complement(26275..26796)
                     /locus_tag="KB902_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6807294.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            26994..30674
                     /gene="nifJ"
                     /locus_tag="KB902_000441"
     CDS             26994..30674
                     /gene="nifJ"
                     /locus_tag="KB902_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBB6807295.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AEKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELQKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHAPAYLHSYNLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVIPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYVQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            30863..31750
                     /locus_tag="KB902_000442"
     CDS             30863..31750
                     /locus_tag="KB902_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBB6807296.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            31747..32916
                     /locus_tag="KB902_000443"
     CDS             31747..32916
                     /locus_tag="KB902_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807297.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            32940..34295
                     /locus_tag="KB902_000444"
     CDS             32940..34295
                     /locus_tag="KB902_000444"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBB6807298.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
BASE COUNT        11303 a         5915 c         7486 g         9666 t
ORIGIN      
        1 gagccattta tacaaatgaa gatgctttgg taataaagaa agaacaagga tttacaggta
       61 cagagaccaa aagcttattc ttaaaagata aaaaagataa taactacgta tatctgactt
      121 ttactacgaa acaaacggat ttcaaagcat tagggaagat cgtcggtaaa aggctttcta
      181 ttgtttcatc agaacgcatg gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt
      241 ttggttatga aaaacagatt ccgattatta ttgatgaaga gctcttatca aatgaaaaac
      301 ttgtttttgc accaggtaga ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca
      361 aaatcatcca gctacttgag atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt
      421 aaccaagtaa aatagtgcat acttggaggt gaagcaacat gataagttat ccattattag
      481 aaagaaatgc aacgattggg gttactgcac catcctcagg cgtatcagag gaacaccatt
      541 cgttactcga atcagcttta aagagaatgg aagaaaaatc tttccaagta gttactggaa
      601 agacgctttg gacgcaagat aaggaaaaat caggtccagc aagaaaacga gcagatgaat
      661 tcaatcaaat gatgcaagat gaaaatatcc aaatgatctt tccgacttgg ggaggagaat
      721 tattgattga gattctcgat tttgtcgatt ttgatgctct acaaccaaaa tggatagtag
      781 gttattcaga tattagtacg ttgctacttg ctgtcacatt aaaaacaggg atagccactg
      841 cacatggaac taaccttatt gatttaagag gagagtactt ggatgaaacg acagcaatgt
      901 gggaaagtgt actgaaaaca agagaaggag aatcgattct acagcaatct tctgaaaagt
      961 atcaaaaagt gtggccccat gagcattcat catcttctgt tttccatctc actgaaccaa
     1021 caaattggca atcagtcagc ggagatgcag taaggatgaa gggacgatta ttaggtggtt
     1081 gtattgatac gatcaggcat ttaatcggta ctccttatgg agatgtccaa tcttttaaaa
     1141 gaaagtataa tgatggaaag ccgatcttgt ggtttctaga aaactgtgag ctatcgtcag
     1201 ttgatttaag aagatcactt gttcagatga aactggcagg ctggtttgat ggcagctcgg
     1261 ggatcatgtt cggtagaagt gcggcagagg atttgttaga ttataaaatg aaggatgtat
     1321 acgaagatct gtcaaaggaa ttaaaactac cgatcttgta tgatattgat tgtggtcatg
     1381 taccgccaca actgacattg attaatggtg cctatgcaga agtagcggta gaagatagaa
     1441 aagcgactgt tttgcaaacg tttatttaaa aaattttttc ctgccttgga gtctatcaaa
     1501 gaccaataaa tctaaataga aaagaaagtg aaagaagctg acaaaatgct gtcagcttct
     1561 ttttgtataa catattagaa agtctaatta tctataactg tcacatcgat taactgtttc
     1621 acgtcattgg gatttcctgt aggaatagct actacagatg cattatcaat gatttcttga
     1681 gttgtttctc taatgaacgc tggataagat gtttgatctg caggcatttg ccaatgtgaa
     1741 ggaactggat aactagtgat tgtcccgtca tggttacttg aatacactaa aactccctgg
     1801 taactgtatt tcccagtgag cataaccaca tctttcggat agactgcact ccctgcatca
     1861 taaggggcga taggtgttcc tgcaggataa tgaataacat gtaattcgaa atcacccgat
     1921 gtatctctaa aagtattacc tctaatagct agccaaacac gtgcgtactc aatttgtaga
     1981 tcagaatatc ctgctaacgg atctattgac tgagaagact gtgaggaggt tgtgtctatt
     2041 gttgaagaag aaatatttgt ctcaactgta ctactagatg tagaagaagt attgggctct
     2101 gagactttac tgcttgttga agatgtattc gtttcagtag aagctgattt ctgagtactt
     2161 gatttttcag ctgaactggt ttgtctgatt gaacttttgt ctgtggtcgc agatggatca
     2221 ctattttctt tactaggaga cgtacatcct acaaggaata aagagaccaa caataaaata
     2281 aaacctaact ttttcatata aaatacctca ttattttttt aataccagta tagcataatc
     2341 ctgaattttt gaatccgtaa aaccttgtct atgaatataa atagagtgta tcttctttga
     2401 taaatgtcag aaaaagtgtg acaaataatc atcagtaaaa ttacttgtca cactattgat
     2461 aaggagtatt taattgaaga gaatgattag gagaaaggat ctccgtactt tttatagtaa
     2521 tcatagaatc caagtttgta tagacgaatc gttttttctc ttatttcttc tgtttcaaaa
     2581 tggactgctt gaagaatcaa gtctgtgaat tctataggag ctgttccatt cgcagtaatc
     2641 aaattacgat ctttcacagc ttgttgttct ataaaatctt ctttattctg ataattttcc
     2701 gattctaacc aaggaaattg cgcatttccg gtgtgtttgt aaccttgcaa taatccgctc
     2761 tgagctaaat aatcaactgc cccacaaata gcagctactg gtacgtctgt ttttaacaat
     2821 ttatcgatta tttgatataa atgatgattt tttatgtccc atgaattgcc accgatcata
     2881 ataaaaaggt caactttttc aggtatttgt tcgattaagt aatcgatttt tgtttttaat
     2941 cctccaatgg aagtgacctc tgattggata gaagcagttt tgttttgcca tttctcattt
     3001 tggtttagtg tgctagtaat ataagcacct tcccaatcgg catattcctc taatagaaac
     3061 gtaatcgcag ttttcatttt caagctctcc tttactatct ataacaagga caacagtttt
     3121 aacctacaga cattcattaa aattgggtag cgacagcgaa aacaacaatt cttaagtttt
     3181 agacagagta tacagatagt caacttaatt aaatacgaac taaataaaaa tgacaggtaa
     3241 tcatttttgt ttaccagcat tataacattt tgcatacatg gatgacaaaa gaaccaattc
     3301 ccacttgctt gagtacaata ttaaaagaaa ctggaaggca aaaagtaatt atagaaacga
     3361 aaaataaatc atatcgggca ctcagacatg aaaacaaccc tagagatata taactaggta
     3421 accagtttaa tgaaagaaaa aatcatccaa gaagtcgatt cttggatttt ttagtggatt
     3481 tgttcgccaa atacgtttag tatgcgtata tgagaggttg taagcaaagc gttgtggtct
     3541 gagcacttaa ggaggaatct gtgaaaatag cttttcatat ttttgcagat tttgacttaa
     3601 tgccgaaggt cagctttgcg attaccgttt atcgagaggc tgtaaaagca ccgtgtagct
     3661 ccgatgacaa taagcaagca tttttagagc taggtttcct tgattctaaa tatgcggctt
     3721 atttcaatga gttggtgctt gaacgcgatt ttaagaaggt cgaaaacagg cacgactttt
     3781 cgacgtaagg agaaagaatt tcaatgatag aaacaataaa tcccgcagaa aacaaggttt
     3841 ctgcgtacat tcatatccca ttttgcgagc atatctgcta ttactgtgat tttaataaag
     3901 tttttttaga agggcagcca gtagatgagt atgtggaaat gctgctgaat gaaatgaaaa
     3961 taatgctaga aagtcatccg acagcgaatt tagaaacact ttacgtaggg ggcgggacac
     4021 caacttcttt atctgctaaa caacttgatc gactgttatc aggtgctaga gagatcctgc
     4081 cttttcaaaa tggtaatgag tttactgtag aagcgaatcc aggtgatttg acccgtgaaa
     4141 aacttcaagt aatgaaaaac tatggcgtca atcgtttatc catgggagtg cagacatttg
     4201 ataatcgctt attgaaaaaa attggacgta aacacaccgc agaagatgtg tatcaaacta
     4261 tgcaattttt agaagcagaa aattttacca atgtaagcat cgatttgatt tatgcattac
     4321 cgggacaaac actagaagga tatctggata ctttggaaaa agctttggct ttggatctgc
     4381 ctcactattc tttgtactca ttgatcctcg aaaacaaaac aatgttcatg aactgggtac
     4441 gacaaggaag actcgaactg cctgatcagg aaacggaaac cagaatgttt gaagagacga
     4501 ttgaagcaat ggaaaagcat ggacgtcacc aatatgaaat aagtaacttt gggctctccg
     4561 gacatgaatc tcaacataac ctcatgtact ggaacaatga ccactatttt gggtttggag
     4621 ctggtgctag cggttatctt ggagatattc gttaccgcaa caaaggacca atccaacact
     4681 atttacgccc attacgagca aatgaacgcc cggtattgga agaagaaaaa ttgacacgaa
     4741 aaaatcaaat agaagaagaa atgttcttag gactaagaaa aaaaacaggg attactaaaa
     4801 aacatttcta tgatcgctat caaaaaacaa ttgaatcggt gtacggtgat gtgctaaggg
     4861 aattagagca agaagggtta cttgttaatg aagaagaccg tgtttatttg acaccaagag
     4921 ggaccttttt ggggaacaat gtgtttgagc gctttttgtt tgaaaaatag tttaaagaat
     4981 atttgttttt tatctgaatt taaataaaaa aagttcaaaa atacaataaa ggactattga
     5041 aacgttgata taactggatt tacatcaatt atttagaatt agcactcttg tgtttagagt
     5101 gctaaaaaat ggagtctttc tcttgacagg agaagggctt cttgctatat ttataagtgg
     5161 attagcactt agaatatatg agtgctaatg agaggtgagg aagatgttaa caaagcgaca
     5221 aaacgacatt ttacgtctga tcatccaaca ctatacgagt agtggcgtgc ccgttggttc
     5281 caaaacattg atgtctgagg gagtcaaggc cagctcagca acgattcgca atgatatgaa
     5341 agcattagaa gatgaaggat tgctgttgaa gactcactct tcttctgggc ggattccatc
     5401 tgctttaggc tatcgttatt acgtggatca tttgttaaaa cctgctcgcg tagcagaaga
     5461 tgatttgctg ctgattcgtc agtctctagg cagagaattt catgaaatca atgagattat
     5521 taagcaatct gctgagatat tatctgagct gacaagctat acgacttttt cattgggacc
     5581 tgaaataaaa gaccgccgac tgactggctt tcgtatcgta cccttgaata atcgacagat
     5641 tattgctatc gtcgtaacag atatggggaa tgtagaaagc caagtgttca ctcttcccga
     5701 atatatggga agtcaggaac tagaaaaaat ggtacagatt gtaaacgacc gtctagtcgg
     5761 agatcctctg atgacggtgt accataaact tcgtacggag attccgatga ttcttcataa
     5821 atatttccaa acgacagaag ggatgtctca gttatttgac accgttcttg gtcatgtttt
     5881 tgaagataag gtttatgtca gtggacaaat gaatctcttg gattatgagc cccgtcaaga
     5941 tcttgatcag ttcaaatcga tgttttcttt tatgaaagac tcagacggac ttacacaaat
     6001 gatcactccg atggatagca atattcatat caagattggt gctgaattag gcaatgattt
     6061 attgcagaat atgagtatga ttcaagcaag ttacgagata gatggtcatg gaagaggtac
     6121 aatagccttg ttagggccta ctagtatgcc ttattctcgg atgttcggtc tagtcgatgt
     6181 ttatcgaaga gaactagcag ctaaacttgc tgattactac cgttcgcttg acttgtcaaa
     6241 ctcgtaatgt gaataacgaa gctatttgca gctgatcgtt ctctctttct tagtaagagc
     6301 aatcaaacag ctgactgaat aatgaaagga agactgtatc gtgaaagaaa atcaagaaga
     6361 actagataaa gaaatgacag atgctcagcc agaaccggaa atcgatgtcg aagctgcaga
     6421 agattcgggt atttcagaag ctgaagcgga agaattcgaa acagcgaaat taaaagctga
     6481 gttagaagaa atggaagata aatacttgcg ggctcgtgct gaaatcgcaa atatggcaaa
     6541 tcgaggaaaa aatgagcgtg agcaattaca aaaataccgt tcacaagatt tagccaaaaa
     6601 attacttcca tcaattgaca acctggaacg tgcattagcc acagaagtgt cagatgatca
     6661 aggggcaggt ttgaaaaaag gcgtggaaat ggtcttggaa agtttgcgta acgcactgga
     6721 agaagaagga attgaaaaaa tccctgctaa aggagaagcc tttgatccta atcttcatca
     6781 agcagtacaa actgttccag cgactgaaga tacaccagcc gatacgattg tagaagtact
     6841 acaagaaggc tacaaattac atgatcgcgt gttaagacca accatggtca ttgttgcaca
     6901 ataattgtgc ggatataaaa cttacacttt caattaaaga aggagacgtt aattatgagt
     6961 aaaattatcg gtattgactt aggtacgact aactctgcag tagcagtatt ggaaggaaac
     7021 gaagcaaaaa tcatcgctaa cccagaagga aaccgtacaa caccttctgt tgtatcattc
     7081 aaaaatggag aaatccaagt aggggaagtt gcaaaacgtc aagctgtgac aaacccaaat
     7141 acgatttcat caatcaaacg ccatatcggt gaagcaggtt acaaagtaga tgtagaaggt
     7201 aaatcatata caccacaaga aatctcagca atgatccttc aatatatcaa aggattcgca
     7261 gaagactatt taggtgaaaa agtcgaaaaa gcagttatca ctgtgccagc ttactttaat
     7321 gatgcacaac gtcaagcaac aaaagatgct ggtaagatcg ctggtctaga agtagaacgt
     7381 atcgtcaatg aaccaactgc agctgctctt gcctatggtt tagataaaac agatcgcgac
     7441 gaaaaaatct tagtattcga ccttggtggc ggtacttttg acgtatctat ccttgaacta
     7501 ggagacggtg tctttgatgt attgtcaaca gctggcgaca accatctagg tggggacgac
     7561 tttgataaca aaatcatcga ctacatggta gcagaattca aaaaagaaaa cagcattgac
     7621 ttgtctcaag acaaaatggc tttacaacgc ttgaaagacg ctgctgaaaa agcgaaaaaa
     7681 gatttatctg gcgtatcaag cacacaaatc agcttgccat ttatcacagc aggagaatct
     7741 ggaccattgc atttggaaat gacattgaca cgtgcaaaat ttgatgaatt aacagctgac
     7801 ttagtagaac gtacaaaagt accagtacgt caagcgctaa aagatgcagg tttatcacaa
     7861 tcagaaatcg acgaagttat tttagtcggt ggatctactc gtatccctgc agttgtagaa
     7921 gcagtacgta aagaaacagg aaaagaacca aacaaatcag ttaaccctga tgaagtagtt
     7981 gctatgggtg ctgctatcca aggtggcgtg atcactggtg atgtgaaaga tgttgtttta
     8041 cttgacgtta caccattgtc attaggtatc gaaacaatgg gtggagtgtt cactaaattg
     8101 attgaccgca atacaacgat tccaacaagt aaatcacaag tattctcaac tgcggcagat
     8161 aatcaaccag cagtagacat ccatgtatta caaggtgaac gcccaatggc tgctgacaac
     8221 aaaactctag gaagattcca attgacagat attccagcag ctcctcgtgg tattccacaa
     8281 atcgaagtaa cattcgatat tgataaaaac gggattgtaa atgtatctgc gaaagatcta
     8341 ggtacacaaa aagaacaaaa aatcacgatc aaatcttctt caggtctaac agacgaagaa
     8401 atcgaacgta tggtaaaaga tgcagaagca aatgcagaag cagataaagc tcgtaaagag
     8461 gaagttgacc tacgtaatga tgtagatgca ttgctattct ctgtggacaa aacattgaaa
     8521 gaattagaag gcaaagtgga cgaagaagaa gtgaaaaaag cagaaacagc tcgcgatgaa
     8581 ttgaaagccg ctgttgaagc aaacaacatc gaagaaatga aaactaaacg cgatgcattg
     8641 aacgaaatcg ttcaaaactt gactgttaaa ctatacgaac aagcggcaca acaacaagct
     8701 caagaaaacc cagaagcagc tcaaggcgga gcagatgatg tcgttgatgc tgattttgaa
     8761 gaagtcgatg gcgacgataa ataatcagtt cactgaattt cgagagaagg ccaaagttgc
     8821 tactttggct ttttcttttg aaaaatagtt tgaagtatcg gtttttgttt caaacaaaat
     8881 atgatatgat aacaagcgac gtgaaaatga tgagaaccaa taggaggaaa gcctatggca
     8941 acaaaacgtg attattatga agtcttaggg ctctcaaaag gagcatcaga agatgaaata
     9001 aagaaagctt atcgtaagct ttcgaaaaaa taccatcctg acatcaataa agaacctgat
     9061 gcggaagaaa aattcaaaga agtatcagaa gcatatgaga ttttaagtga cccgcaaaaa
     9121 cgcgctgcat atgaccaata cgggcatgca ggcacagatc caaattacgg tgctggtgga
     9181 gctggtggcg gatttggtgg attcggcggc ttctctggtg gcggcttcgg tggttttgaa
     9241 gatatcttcg actctttctt tggaggaggc ggtcggtcag tcgatccaaa tgcgcctcgt
     9301 caaggtgctg atttgcaata tacggtcgac ttgtcttttg aagaagcgat ttttggtgta
     9361 gaaaaagaaa tcaagtataa tcgggaagaa atctgtcata cttgtggtgg gaacggtgca
     9421 aaaccaggca cacaaccaac tacttgtcat aaatgtcatg gtgcaggtac gattaatgta
     9481 gaacgccaaa caccacttgg acgagtgatg agccgtcaaa cttgtgatgt ttgtcatggg
     9541 acagggaaag aaatcaaaga accttgtcca acctgtcatg gctcaggaca tgagaagaaa
     9601 gcacattcag ttaaagtgaa tgtaccagct ggtgtagaag aaggacaaca aatgcgttta
     9661 gctggtcaag gagaagctgg agaaaacggc ggaccatttg gtgatttgta tgtggtcttc
     9721 cgtgtagaag aaagtgatat ctttgatcgt gaaggttctg aaatttacta tgaattgcct
     9781 ttaagttttg tacaagcagc tttgggggat gaagtccaag taccaactgt ccatggagat
     9841 gtgaaattga agatccctgc tggaacacag acaggtacga acttccgttt acgtggaaaa
     9901 ggcgctccga agttacgtgg tggtgcaaca ggcgaccaac atgtcaaagt aaaactgatc
     9961 acaccgaaaa atctaaatga acaacaaaga gaagcattac gtgcattcgc tgaagctggc
    10021 ggcatcaaag ttgaagaaca gcaagaagac ggtttcttcg ataagtttaa agatgctttt
    10081 ggcgggaaaa agcggaagta gtttttctag taaaaacgct aagtcattaa taattaaaaa
    10141 ccagacgaac aatcatatgt tcgcctggtt tttttgtagt tgtcatgttt gtaccaacaa
    10201 aaaagccagc tttagaatat gataatcgtc atagtttcta ggggtataac cagtgagaga
    10261 atggaacttg ttcaatcgat attgcaaggt gtttttatga ataaataatt cttctgagca
    10321 atttttgatg cttccgttat ttttactgaa gcatgccaaa gtcttcttga acaaatgtac
    10381 ttcttcttct gtcaggcttt tcaaaatacg ttttacatat aatgttcgtt gatctgacgg
    10441 gattgctggt aaaacgatcc cgaggtctaa atcttcaaaa aagcggatct cgttcacaga
    10501 ttgatggaaa gctatccatt cgcaaacttg tttggcatga aggaaagatt gcggtgtctc
    10561 ttgctctgta taacaaagcg acccaattcc aaagtttagc tgtaactgat acattttatt
    10621 aaactttgtc tggattttat caagcaatga tagcaatgag gctctggaaa tccgattgac
    10681 taggataatg atttgttgtc tatgtacagt gagcaaagcc tgtccgtaat aagagaagac
    10741 cctttcgagc aactccaata aaggattgat ccgttcttga cacaattgct gattgtcaga
    10801 aagttgtccc acaactacat aatatggaga agaaaaatca agctcaatta agtgagggtg
    10861 gtatcgacta tgtacttgat atcatcaatg aaccgatggt actttcttat gcgatggaac
    10921 aggtagagcg attgcttgtt tgtgcaggaa aacaagcgat gcggctgata cgattaggtg
    10981 agaaaataag aagataaaaa tacacggtcc cttcatggcg accgtgcatt tttggttttt
    11041 attaaatatt taatacttta ttcaagaaat cttttgtccg ttcattttgc ggattttcaa
    11101 agatttgttg aggcgttcca tcttctaaaa agtttccgtc gtcaatgaac atgacgcgat
    11161 tggccacttc tttagcgaac cccatttcgt gcgtaacgat aaccatcgtc ataccttgtt
    11221 ctgctaactt tttcatgacg ttcaagacat caccgaccat ttcaggatcg agtgcagaag
    11281 taggctcatc aaaaagcatg atgtcagggt tcatcgctag agcacgagca atagccacac
    11341 gctgtttttg tccaccagaa agcatttcag gatacatatc ttttttatct tctagaccaa
    11401 ctgtctgcag taatttgatt gcttttttct ctgcttcttc tctagattct ttcttcaggt
    11461 ccatcggtgc taaaatgatg ttttccaaaa tagaaagatg agggaatagg ttaaagtgtt
    11521 ggaataccat tccgatatgt tgtctcacca agttgatatc tgtgctttta tccatcaagt
    11581 gggcgccgtc aataataatt tcaccgtcag aaggttcttc taaacgattc aagcaacgca
    11641 agaatgtact ttttcctgaa cctgaagggc caatgataca gacgacatct ccttcgttga
    11701 tggatacatt gatgtcgttt aatactgtgt tatcgccgta ttttttgact aaatgctcaa
    11761 ctaagatttt ttctgccatc ttacttcacc ttcttttcta aaacttttgc taattttgtc
    11821 aatgctgtga tcaaaatcaa gtacatgatc gcaatgatca agtaaacata cgtactttgt
    11881 gttgtacgtg caacaatgat cttaccagtt tgcagcaatt cgactacacc gattgcggaa
    11941 atgatcgttg tgtcttttaa tgagataacg aactgattga cgaatgatgg gatcatgatg
    12001 cgtatcgctt gcggcaaaat gattttttgc attgtccgat tataagaaag acctaaactt
    12061 ctggaagctt ccatttgtcc gacaggaacg gcgttgatcc cgcctcgaac aatctctgcg
    12121 atataagcac ttgcgttaag agtcaaggtg ataacaccag caaggaagtc aggaatcgta
    12181 aatccaacga taccaggcaa cccaaagaaa ataaagaacg caagaaccat cattggaatt
    12241 cctcggatga tatcgacata aatactagca attgtgcgaa gagcgcgtat tggtgctaca
    12301 ctgaataatc caaaaatcac accgattact atagccaaag caaaggagat caaagttagg
    12361 agaattgttc tccaaagtcc tttcaacaat gcttgatagt tgttttggat aagtccaaga
    12421 aatgttgatt catcagcagt ggaagactca ctggaagttt ctgaaccatc cgctacatat
    12481 tctttaataa tcttatcgta ttcgcctgtt ctttttaatt ctttcaatcc ttcattgaac
    12541 atattaagaa gctcaggatt ttgtcctttt ttaacggcaa atgcatattt tccgccagat
    12601 tcttttttga tcggtgtttc caattcttgt ccttgtttga tcgcataacc gattaccgga
    12661 taatcatcca tcattgcatc gattgcgcca acttttaacc cgtcgtacaa ttgatcagca
    12721 gcatcaaaat atttgataga atagccatat tcagattcat ggtcgcttaa aaattcagca
    12781 ctttcggtac caacttttgc tccgactgtt tttcctttca aatcttcata agacttgatc
    12841 gaagtatctc cttttttgac agctaattgg atcccgctat caaagtaaga atcagaaaaa
    12901 tcatagcttt tctttcgttc atctgttaca gtcattccgg caatcattcc gtctgcttgt
    12961 cctgattcca aagcttgcaa agcagcagag aaaccacggt agtccattcg gatgttaaat
    13021 ccttgcagtt tggcgatgtt ttccatcaat tttacatcga tgccttcgta ctcgcccttt
    13081 gcgttttgaa attcaaatgg agcaaaagca gagtcactgg caattacgta tacgtctttt
    13141 ttgggctcta ttttttgcat tgtctcgctt gtgcttgact ctgccgttgt agtgttgtca
    13201 gcttgtgcaa catgtccaaa cgcaagtgtc acaagtcctg tcattaagaa aacaaatgag
    13261 tgaaataaat gctttctttt cataatcaac ctcctaaatt tccaatattt tattattata
    13321 ggcgaaaagt gctgaatcag acaagactgt aagctcgaaa aaatgaaaaa aatgcgagtt
    13381 tctaacattt tatgttataa aacgtaacat gcataataag ataaaaaagt ggcgaaagta
    13441 tgttcggtgt ggtataattt tttagtaagg aatgcctttg ctttcctttt ctttttattg
    13501 gtcgtaaaat gaaaaggaat gaatgaaaag gaggacgaag aatgattgag agagatacct
    13561 cccgacactt tgagcttgtc tcgaaatacc aaccggctgg tgatcagcct gaagcgatta
    13621 accaattagt ggatggcgta gtcggcggga aaaaagcaca aatcttatta ggtgcgactg
    13681 gaacagggaa aacatatacg atttccaatc ttattgagaa agtgaataaa ccaacactaa
    13741 ttattgccca taacaaaaca ttggctggtc agctgtacgg ggaattcaag gaatttttcc
    13801 ctaacaatgc tgttgaatat tttgtttctt attatgatta ttatcagcct gaagcttatg
    13861 tgccttcaag cgatacgtat atcgaaaaag attcaagtgt aaatgatgag atcgacaaat
    13921 tacgacattc ggctactagt tcattattag aaagaaatga tgtgatcgtc attgcatccg
    13981 tttcatgtat ttttggatta ggttcgcctt ttgagtacca aaaacaagta gtttcgattc
    14041 gacagggagc agaactagat cgcaatcagt tgattcgtga cttagtcagt atccaattcg
    14101 aaagaaatga tatagatttt cagcgcggtc gttttcgagt gcgcggtgat gtcgtggaga
    14161 tttttccggc ttcaagagat gaacgtgcct tacgtgtgga gttttttgga gatgaggtcg
    14221 aacgtatccg agaagtcaat gcactgacag gtgaagtttt aggagaaacg gaacacgtgg
    14281 caatcttccc ggcgactcac tttgtgacga atgatgaaca tatggagcat gccgtagcga
    14341 atatcaaagc ggaattagaa cagcgtttaa ctgtcttgcg aaatgaaaac aaacttctgg
    14401 aagctcaacg tttagaacag cgaaccaatt acgatattga aatgatgtta gaaatgggct
    14461 acacgtcggg aattgaaaat tattctcggc atatggacgg acgtaaagaa ggtgaaccgc
    14521 cttatacgct attggatttc tttcctgaag attttttgat cgtggcggac gaatcgcacg
    14581 taaccatgcc tcaagtcaga ggaatgtata atggtgaccg agcgagaaaa cagatgctag
    14641 tagattacgg tttccgtttg ccatctgctt tagacaatcg gccacttcgg ttagaagagt
    14701 ttgaaaaaca tgtcaatcag atcatttatg tctctgcgac gccaggacca tatgaacatg
    14761 aacaaacaga taccgttatc caacaaatca tccgtccgac agggctgctt gacccagtga
    14821 tcgaagttcg tccaatcatg ggacaaatcg atgatctagt aggcgaaata aatgaacgag
    14881 tcgaaaaaga ccagcgggtg tttgtaacga cattgacgaa aaaaatggca gaagacctca
    14941 cagattattt caaagaatta gggatcaaag tcaaatattt gcatagtgat atcaaaacgc
    15001 tggaacgaac agaaatcatt cgagatcttc gattaggtga atttgatgtg ttagttggaa
    15061 tcaatttgct tcgtgaagga ttagacgtac ctgaagtttc ccttgttgct atcttggatg
    15121 cggataaaga aggcttttta cgtagtgaac gttccttagt ccaaacgatt ggacgagctg
    15181 ctcggaatga agaaggtaaa gtaatcatgt acgcagacaa agtaacagat tctatgcgtc
    15241 tagcgatgga tgaaacatca agacgccgta cgattcagca gaagtacaat gaagaacatg
    15301 ggatcgttcc aaaaacgatc attaaagaaa tccgagattt gatttctatt acgaaagaat
    15361 cggaagatga tacaaaagaa gcggtacaag tctcgtatga agaaatgacg aaagaagaaa
    15421 aagatacgtt attgatgaaa ttagaaaaag aaatgaaaga tgcggcgaaa gcattggatt
    15481 ttgaaacagc cgctaatgtg cgagatatga ttttagaatt aaaagcttca aagtaggagg
    15541 acaacatggc taacgataaa attacgattc acggtgcacg tgcccataac ttgaaaaata
    15601 tagatgtaac gattccacga gataaattcg tggtcgttac aggtttgtcc ggttctggaa
    15661 aaagttccct agcatttgat acgctgtacg ctgaagggca gcggagatac gtagagagcc
    15721 tttctgctta tgctcgtcag tttttaggac aaatggataa gccggacgta gatagcatcg
    15781 acggattgag tccggcgatt tctattgatc agaaaacaac aagtaaaaat cctcggtcga
    15841 cagtaggtac tgtgacggaa atcaatgact atttacgctt gttgtttgca cgtgtaggac
    15901 atccgatttg tcccaacgat catatcgaga ttaccagtca atcagtagat caaatggcag
    15961 atcaagtaat ggctttgcct gagcgcacaa agatccaagt gttggcaccg atcgtggtaa
    16021 agaaaaaagg acaacataaa aaaatattcg aacgaatcca aaaagaggga tacgtccgcg
    16081 ttcgagtcga tggtgagatc tatgatttaa gtgaagtgcc tgagctggag aaaaacaaaa
    16141 aacatgatat cgcgatcgta atcgaccgga tcattgtgaa agaagggatt cgttctcgtc
    16201 tatttgattc tttagaggcg gctctgcgat tggcagacgg ctatgctctg gttgacgtga
    16261 tcggtgaaga agaaatgttg tttagcgaac actatgcctg tccttattgc ggatttactg
    16321 ttggcgaact agaaccaaga ctgttctcat tcaatgcgcc ttttggagct tgtccagact
    16381 gtgatggttt aggtgtcaaa ttagaagtcg atcaagattt agtgattcca gatagaacga
    16441 agacacttag tcaaggtgct atcgttccat ggaatccaat cagctctcag tattatcctc
    16501 aaatgttagc gcaggcttgt gaaagtttcg gtatcgattt agatacacca ttcgaagaat
    16561 taccggaaga gcatcaggat atcatcttga atgggacaga tgatcttttc catttccatt
    16621 atgaaaatga ttttggtggc gttcgcgatg tagaaacgac tttcgaaggg gtattgaaga
    16681 atatcgagcg tcgttatcat gatacgaaca gtgatttcac gcgtgagcaa atgcgtcttt
    16741 atatgacaga attaacttgt cagacatgta aaggttatcg attgaatccc caagctctat
    16801 ctgttcaaat caatggaacg aatatcgggc aaacaaatga gttgtctatt caaaaagcag
    16861 tagatttctt ctcaaactta acgttatctg aacaagagaa agtaattgcc aaaccgattt
    16921 taaaagaagt aaatgacaga ctttcattct tggaaaatgt gggactagac tatctaactt
    16981 tgagtcgcgc ttccggaaca ttatctgggg gagaagcgca gcgaatcaga ttggctacac
    17041 aaattggatc gaatctttct ggagttttgt atattttaga tgaaccatcg atcggattgc
    17101 atcaacgcga caacgatcga ctgattggct cattaaagaa aatgcgtgat cttggcaaca
    17161 ccctcgttgt agtcgaacat gatgaagata cgatgtgggc agcagattat ctgattgacg
    17221 tcggacctgg ggccggagaa caaggcggac aaatcgtggc tgcaggcact cctgaagaag
    17281 tagctaatga tgaaaattct ttgacaggga aatatctttc agggaaaaaa tcaatccctg
    17341 taccaaaaga acgccgtaaa ggtaatggga aagcaatcaa gatcactggt gcttcagaaa
    17401 acaatctgaa aaatattagt gttgaatttc cattaggaga atttgtagca gtcacaggtg
    17461 tgtctggttc tggaaagagt acattggtca atagtatctt aaagaaatcg ttagcgcaaa
    17521 aattaaataa gaattctgct aagccaggta aattcaagac aatttccggc tacgaaagta
    17581 tcgaaaagat catcgatatc gatcaaagcc caatcggccg gacgccgaga agtaatccag
    17641 cgacttatac aagtgtattt gatgatatcc gtgggttatt tgctcaaacg aacgaggcaa
    17701 aaatgcgggg ttataagaaa gggcgtttta gtttcaacgt aaaaggcggt cgttgtgaag
    17761 cttgtcgcgg ggatggaatt attaagatcg aaatgcactt tttgcctgat gtctatgttc
    17821 cttgtgaagt atgtcatggc aaacgatata actctgaaac attagaagtg cattacaaag
    17881 gaaaaagcat tgctgatatt ttggaaatga cagtagaaga tgctgtagaa ttcttcaagc
    17941 acattccaaa gattcatcgc aaactgcaaa cgattgttga tgttggctta ggttatgtga
    18001 cgatggggca accagcaacg acattgtccg gtggtgaggc acaacggatg aaacttgcca
    18061 gtgaattgca caaaatctct aatggaaaga atttctatat actagatgaa ccaacgacag
    18121 gacttcatag cgatgacatc gcccgcttgt tgcatgtatt acaaagatta gtagatgctg
    18181 gtaacacagt tttagtgatt gaacacaatc tagatgtaat caaaacagca gattatatca
    18241 ttgatttagg accagaaggt ggagaaggtg gaggaacgat ccttgcgact ggaacaccag
    18301 aagaaatcat taacgtaaaa gaaagttata caggtcacta tttgaaaaaa ataatggtat
    18361 aaagaggata gatagctgag atagttaaaa aaacataaaa aaatgaattt ttgcttgttt
    18421 tattaatatc agtgttctag aatcattaca tggtagttct ttctacactg attggtatag
    18481 acaaaaactt cctataagtt caatccgttc aaaaaagaat tgagcaatcg gaggagtttc
    18541 ctttgattgc ttttttcttt atggtatgat attccttgtg tagttggaaa agaaaaacaa
    18601 gagattatga gtaagtgaga gataatgatg aacagtattg aaaatgaaga atttatccct
    18661 atattattag gaagcgacat gaacgtttat ggtatggcac gttcttttaa tgaagcatac
    18721 ggcaaaatct gccaagcata tgcttcggat cagttagccc ctacccgcta cagtaaaatt
    18781 gtcaatgtag aagttattcc aggatttgat aaagaccctg tgtttatcga gacgatgctt
    18841 cgtttggcaa aagaaagata ttctgataag agtaaaaaat atcttttgat tgcttgtggt
    18901 gatggatatg cagaattgat ctcccaacat aaacaagagc tgtcagaata ttttatctgt
    18961 ccatatattg attattcttt atttgaaaga ctgatcaata aagtaagctt ttatgaagtt
    19021 tgtgaagaat atgatcttcc gtatcctaaa acattgatcg tcagagaaga aatgttagta
    19081 aatggacatt tggaacagga attgcctttt gaattcccag ttgctttgaa acctgcaaac
    19141 agtgtggagt atctttctgt ccaatttgaa ggaagaaaaa aagcttttat tttagagact
    19201 agagaagagt tcgatttaat tttaggccgg atatacgaag ccggttataa aagtgaaatg
    19261 attgtacaag attttattcc gggtgatgat agtaatatgc gtgtgctaaa tgcgtatgta
    19321 gatgaagatc atcaagttcg gatgatgtgt cttggtcatc cactgttaga agatcctaca
    19381 ccagcatcga ttggtaatta cgttgtgatc atgccagatt ataacgaaaa aatctatcaa
    19441 accattaagg catttttgga aaaaatcgaa tatacaggct ttgccaattt cgatatgaag
    19501 tatgatccta gagatggaga atataaatta tttgaaatca atttgagaca aggtcgtagc
    19561 agtttctttg tgacattgaa cggcttgaat ctggctcgtt tcgtcacaga agatcgagtg
    19621 tttaacaaac cctttgttga aacgacctat ggaacgaatc aatcagataa agcaagatta
    19681 tggatgggtg tgcccaaaaa aatcttttta gaatatgctc gggaaaatga agacaaaaaa
    19741 ctagctgagc aaatgatcaa agaaaatcgt tacggtacta ctgtgtttta tgaaaaagac
    19801 cggtcaatca agcgctggtt gttgatgaaa tatatgttcc ataactatat tccaagattc
    19861 aaaaagtatt ttcatgtgaa agaaggctag ttcatggaga attttttcag tattttaggc
    19921 ggaatgggca cgatggcgac agaaagtttt gttcgcttga tcaaccaccg aacgaaagct
    19981 acaaaagatc aagaatattt gaattatgtc ttattcaatc atgcaacagt tcctgatcgt
    20041 acagcttata ttttagatcg atcagaagaa aatccaatgc cgtttctgct ggatgatatt
    20101 gagaaacaaa atttattgca gccgaacttc attgtgttga cttgtaacac cgcacactac
    20161 ttttttgaag aattacaagc ggcaacggat attcctatcc ttcatatgcc aagagaagca
    20221 gcaaatgaac ttgtccgtca gcatacgaca gggagagtag cgattctagg aacagaagga
    20281 agtatgaaag ctggaatcta tgaacgcgaa gtcaaaaatc ttggattcga aacagtgatt
    20341 cctgatactg ttcttcaaga aaaaatcaat tatctgatct atcatgagat caaggaatcg
    20401 gattatttga atcaagagct atattacgaa atcttagaag aagcggtaga gcgcctaaac
    20461 tgtgaaaaag ttatcttagg ttgcacagaa ttgtcattga tgcatgaatt tgctgaagat
    20521 aaccattatc cagtgatcga tgcccaatct attttagcag atcggacgat tgaacgagcg
    20581 ctagctgaaa gaagcaaggc attggataca gcatcggaaa agtaaaaaaa ttggatttgg
    20641 ggcaaatatc ctaaaagata tttggtccaa atctttttgt aaaagaaaaa gaaaactggt
    20701 aatgatacgc ccggaatgat ataattttac tatgcacaat gtgagaggag ttcgtaatta
    20761 tgacagataa tttgcaatta gtcatcataa caggtatgag cggtgcaggg aaaacagtag
    20821 ctatccaaag ttttgaagat atgggctatt tttgtatcga taatatgccg cctcgattga
    20881 ttccaaaatt ctgggaatta atcaaagaat caggcaaagt cacaaaaatg gctttaggag
    20941 tggatttacg ttctcgttcc ttctttgaag aaatccaaaa catgctgatc gaaatcgaaa
    21001 atacgaactt catcgacact tctatcttat ttttagatgc ttcagacgaa gaactagtgg
    21061 ctcgctacaa agaaacaaga cgagcacatc caatggcgat ggacggtttg atcactgaag
    21121 ggatacgtaa agaacgggcg atactagacg acttgaaagc ccaagcttcc gtgatcattg
    21181 atacgacgac attgacacca cgacaattac gtgaaaaaat caatgagtca ttcaaatcaa
    21241 agggagacca aggatttcgg atcgaatttg tatcatttgg ttttaaatac gggttgccga
    21301 tcgattcgga tattgtgatg gatgtgcgtt ttttgcccaa ccctcattat atcccggaac
    21361 taagaccatt gaccggaaaa gatcagccag tctatgatta tgtgatgtcc tttgatgaaa
    21421 cgcaatcatt ctaccataaa tttttggatc ttctggaaac tgtattgcct ggatacatta
    21481 aagaaggaaa aagcagcttg acagttgcaa tcggctgtac aggcggtcaa caccgttctg
    21541 tggcattgac tgaacgtttg gcaaatgctt tagggaaaaa ctataaagtc aatgtgacac
    21601 atcgggacaa ggataaaagg aaagagacgg tgaaccggtc gtgaaaatga aaacctaccg
    21661 gataagaaaa ccaaagatcg tagtggtcgg cggtggcact ggtctgccag ttatcctgaa
    21721 aagtttgcga aatcaaggag cagatatcac agcagtagtg actgttgcag atgatggggg
    21781 aagcagcggt gcaatcagag aatcgatcgc tatggctcct cctggtgact tgagaaatgt
    21841 cttagtggcg ttatcggata tgccacaatt ctatgaagat attttccaat accgtttcaa
    21901 aaaggaagat cagtttttag ccaatcatac gatcggtaat ctgatcattg ccgcagtttc
    21961 cgagatgcgg ggaagcactt atgaggcgat tcaattatta gcaaaaatga tgcatgtaga
    22021 tggacatgtt tatccttctt cagaaactcc tttgaccttg catgctgtct ttaaagacgg
    22081 aacgactgca gtaggagaat ctaaaatcgc gatcgaccgt aaaaccattg accgtgtgta
    22141 tgtctgcaac acaaatgata aaagtgaagc caaagcggct cgaaaagtcg tttcagcaat
    22201 tatggacgcc gacatggtcg ttttgggacc cggaagttta ttcaccagta tccttccaaa
    22261 tttagtgata ccagaaatcg gcgaagcaat gctcaagaca actgctgaaa ccgtctatat
    22321 ctgtaatatc atgacccaaa aaggggaaac ggaacatttc acagatgccg atcatatacg
    22381 tgttttacac aagcatttga atcagccttt tatcgataca gtattggtca atacggaaaa
    22441 agtgcctgaa gattatatgg acccagagat ctatgatgag tatctagtac aagtcgcaca
    22501 cgacttcaac ggattgagaa atgaaggatg tcgagtgatt tccaccgact ttttggaatt
    22561 gaaagatggt ggtgtcttcc acgatggaga caaagtagta gaagaattgt tccgtttagt
    22621 tttcggttca aaatattaag caatttattg ttggagaaag gaggagaata ggatgtcatt
    22681 tgctgcagat gtgaagaaag aactaactgg tttggaagtt catcgagaac atgcgaaagc
    22741 ggaattagct gctttgctgc gaatgaacgg ctctttaggt attgtgaacc agcagtttat
    22801 tttgaacgtc caaacagaaa atgctgcaat tgccagacgt atctattctc ttttgaaaga
    22861 tcattatcag gtacgaagtg agctactcgt tcgtaaaaaa atgaaattaa aaaagaacaa
    22921 tgtctatatc gtccggttga agcaaggcac aaaagatgtg ttgatggatc ttgatatcat
    22981 ggatggtatg atgttcaatg gacacgtttc ggacgagatt atgggaaatt cgcaaaaaat
    23041 gcgttcttac ttacgtggtg cttttatggc ctcaggttca gtcaataatc cggaaacgag
    23101 ccgttatcat ttggaaatat tttctattta tgaacagcat aaccaagaca tttgcgatat
    23161 gttaaattat tacggtctac atgctcgaac gcttgaacgg cgcaatggct atatttctta
    23221 tttaaaagga gcagaaaaaa ttgctgattt cttaacattg attggtgcaa ccaactcaat
    23281 gctccgattt gaagatgttc gaatcgtacg ggatatgaga aattcggtca atcgtctagt
    23341 caattgtgag acagcaaatc tgaacaagac gattgatgcg gcttctaaac aaatcgaaaa
    23401 catcgaattg atcgaagcaa aggtcggtct acatgccctt cctgaaaaac ttcaggaaat
    23461 cgcagaactt cggcttcaac atccagaggt cagcttgaaa gaattagggg aaatgattcc
    23521 ctcaggtgcg atatcaaaat cgggaattaa tcaccgaatt cgcaaaataa atgaatttgc
    23581 ggaaaaactg cgtgaagaag cagtttaatc caaagaaaaa actgatacat gaagcaggag
    23641 atgcgaatgt atcagttttt tttaaaagtt atacttgctt ttcttccgtc aaactataat
    23701 tccatcttta ctggagtaac ataatttgga aaggcttcta ttgtttttaa tacaatcgta
    23761 taaaaagcgg ggagacaact gaatgaagat tttagttttg tacataaatt tttgcttaat
    23821 atagaagtcc tgatatagat aagatcaagt atttatctat aactggcctg attaattaaa
    23881 aaactggaag gaactgctcg atcatccttg agaactgctc ttcttacttc tggtcaagat
    23941 tctcgtggtt ggtggataag gatggttgat aagttcattg gattagctag tcgaaaacaa
    24001 ccaggtgtaa ttaatgtaga agttttaaca aggggatgga gtgatttatt cagtgataat
    24061 cataagttca taaatagtaa ttgagatgta tggttggaat acgttatacc tgaacttgaa
    24121 ctaccaagat ttggtttaga atttgagaat cgatgtttat aaagggaggg caaaaatgcg
    24181 tttttttaca acttttacta tcattatgat tgcagtactt tttatttttc tagatatagc
    24241 aaagcgaaat acagcatttt tattatatcg ggttttactt cgagcaggtc tcataacatt
    24301 tatatcgatc gttggatttt ttctattcac agttattgta tttatttgga gaactccagc
    24361 accaccattg ccagagatta catatggaga atttcctttt agacttgagt atgaattgaa
    24421 tgaagaatta catgtgatag aagacacgtt aatagttgaa tttgatggat ttggaatgaa
    24481 cgaaggcata gggagatatc gtagatggac aagtcgttta gccagcggag aagatttagt
    24541 gttgctgtta gaagttagtg ataataagca aatattttat tttccaggac ctgctaatta
    24601 ttacatggga gataggttga atggttataa tcatactttt cctagtgctt ctttcattga
    24661 aagggaaaga ggcattacta gaagggatat tttacatgac aaagaattat tagaacaatt
    24721 tggtccgctt gatcaaaata caataaatga agaagaattg ttaaatcaat ataatataag
    24781 gctagtgaat tgggaaatat ctgaaccgat tgttaacaat tttggtgatt agaaaacaat
    24841 tacgataaat agaaacaagc caaatcatca gcaagtaaaa gctgatgatt tggcctttct
    24901 tatacgagta gtaggaattc atagcgaata ttattacgat cagtagatat tttgatatta
    24961 aaggagtatt acgaactagt atgtgagaat gtagaggtga tttgcgaata atgagaaatt
    25021 tatcaaatag aaacaaaata ttaatcatta ttgttgttat agctgtgttt catctgggaa
    25081 cgaatgcggt tttaagtaga ataatattgg gtcctaagcc accaagacct gcgattaccc
    25141 gaggggagtt tgattttaga ttagaatatg aagtagatgg ggaaaggatt gtgatagaag
    25201 atacaattgt tgcattattt gatggatttt ctgcagatgc aggtagcatg gcatggtatc
    25261 gcacgtggcg tttgcatttg gcgagtgaca agagggcaca acaattattg ttacatgagt
    25321 tagatgatgg tcgaaaaata tattatcatt ttggaggagc tggattttat atggggaagt
    25381 tagtagcagt gtaactgtaa caaggaaaga tttgccaggt cttggcattc gaaactccat
    25441 attttatatc gagcgtggga gagatacatc tattgggaac aggaaagggt taactcttga
    25501 agagttatat aatgactttg gaatccgtct tgttagttgg gaacacaatc caccaataga
    25561 aaatcgcttt gaataatcga aatctattaa tccatttcat cagccagtga atgttgtaat
    25621 ggaacaattt ggtttagtgt tcaaaaccat tgaaatacta ggctgtgatc agcaaaaatg
    25681 tatctgaata aaaaagagag caactattaa atgagaggag ttaggagttg ttagctttat
    25741 acgaatcaaa gtggcaaata cagatgcgta tgcatttgtg tttgccatct tgcgtttggt
    25801 agacgagata ggtataagct aaagaaacaa cttgtttaaa ataaacgacc tagctcaaca
    25861 aacgactatc taatcaacta acagcataca taaaagcaac tatttttgaa gtagaattga
    25921 aatcgggata acttaaaaag tgattgggat actagtgtga atcaccgtac ataaatatta
    25981 ctcgttaagg gaatttgaga aattttgtat gaaaatttaa gaattagtta gtatgcgcaa
    26041 gtcaaaaata tgaataaatt atttggtgga gataatttgc tcagcttgtc ataagaaatg
    26101 agataatctg gcagatgcaa gcttttggac accatttatt cggaataagg aggctgggac
    26161 agaagcgttt aactccaaga aataagaagg agttgcttct gcttccgctg tttataggtg
    26221 tttagagcgt gagacaaaag tgttctttac ttttgtccta cgctccttat ttttttattt
    26281 tgtttggatc aattctttta attcctctat tgaaatagat tcatcaaaga tttctttacc
    26341 caagatgaca gtcggaacaa atcgaatatg tgcttgctca gcttcgttga tgacagcttg
    26401 gctcagctgt tcgtcttttt gttctgtcag ctttagttta tctactgcaa aatccgctac
    26461 ttcttggaga gaaagatgtt tccactcgtc ttgagtatcg aatatttgtt tgatctcttt
    26521 gatcgctttt tgaccatcgc tgattgtgag ataccggtgc atcacgtttc ctcgctgcaa
    26581 gctttctttt tctttatcga acaatttgat cactcgctgc aattgcccgc tttggactgc
    26641 ttcttctaat agctcataag attcttcaaa ccattgtcgg caatacggac aagataggtt
    26701 gatgaattcg accatttttt taggagcatt cgatgaacca taaaggattc ctttttgtgt
    26761 atttgttttc gttgcatcaa tcactgatat atccatgtta aaacacctct ttcgcttata
    26821 gtttatacat gtctgacaaa aaaaggcaac gatttagact gtttgtctaa aaattagatg
    26881 accaattcaa atagacatat gtgaaatatt tttataaata aaagaaaaaa tggaatgttt
    26941 tacgttataa tggaacagat aataagagag aatatgaaca aggatgatga atcatgcgaa
    27001 aaatgaaaac aatggatggc aatacggcag ccgcatatat ttcttatgca tttaccgaga
    27061 ttgctgcaat atatccaata acacccagtt cgaccatggc tgaattagta gatcaatggt
    27121 cagcagcaga aaaagaaaat gtattcggtc aaccagtaaa agtagtagaa atgcaatccg
    27181 aagcaggagc agctggtgtg gtccatggat cattgaaaac tggtgcactg acaactacat
    27241 ataccgcttc tcaagggctg cttttgatga taccgaatat gtacaagatt gctggggaac
    27301 tactgccaag tgttttccat gttgctagtc gggcagtgac gacaaatgcg ttgaatattt
    27361 tcggagatca cggagacgtg atggctgcaa gacaaacagg atttgctatg ttagctgaaa
    27421 gcagtgtaca agaagtgatg gatttagcac ctgttgccca tcttgcttct attgaaggag
    27481 aagtaccttt tttgaatttc tttgatggat tccgtacgag tcacgagatt caaaaaatcg
    27541 aagttttgga atatgaagaa ttagctcctc tgatcaatca ggagaaatta gcttcatttc
    27601 gtaaaagagg gatgaatccc aatcatccga ctgttagtgg tacgaaccag aatccagaca
    27661 tccattttca acaacgggaa acgatcaacc cctattatga taaattacct gaaatcgttc
    27721 aaaaatatat gaaagagatc aaccgattac gaggaacttc ttatgacttg gtgacttatt
    27781 acggagcaga cgatgcggaa gaagtcattg tttctatggg atcagttgca cagacgattg
    27841 aacaaacgat tgattacttg aatgcaaacg gacggaaaac aggttttttg aatatccatc
    27901 tttatcgtcc ttttccagtg gaaacattcg tgcaaaagtt gcctcataca gtaaaaacaa
    27961 ttgctgttct tgatcgaagt aaagaaccag gggcaggtgg agaacctctc ttattagacg
    28021 ttcaaagtgc gttatatgat tctgaacttc gcccggctgt tattggtggt cgctacggat
    28081 tgggttctaa agatgtgact cctgaccaaa tctcagcagt ttttgatgaa ttgcaaaaag
    28141 acccaagcat acgcaaaaaa cgtttcacca taggtatcgt tgatgatgtg acttatcaat
    28201 ctttggaacc aaaggaaagt ctggatttga cagaaccgca aacattccag gccaagtttt
    28261 gggggtttgg atctgacgga acagtcggag caaataaatc agctatcaag attattggag
    28321 atcacaccga taaatatgcg caaggctatt tttattatga ttcgaaaaaa tctggtggtc
    28381 tgactgtctc tcatcttcgt tttggagata cgccgatacg ttctgcgtat cttgtcgagc
    28441 atgcggacct tgttgcctgt cacgcaccag cttacctgca tagctataac ttggtcaaag
    28501 gattgaagcc aggtggcatt tttttattga atactctttg gagcgacgaa caattagaaa
    28561 cgcatctgcc cttaaaatta aaacgttact tggctgaaaa taacattaga ttctatacga
    28621 tcaatgccat gagattggcc caagaagtcg gtttgggacg ccggatcaat acggcaatgg
    28681 aaacggcatt ttttaaatta gctgacatca ttccttttga tgaagtgatt ccgctgctaa
    28741 aagaagaagc cctgaaaagc tatggacata aatcaatggc tatcgtagaa aaaaacatac
    28801 aagcaatcga ccggacgacc gaactgcttc atcaagtcgc gatcccagac cattggagaa
    28861 cgttggagat gcctgaaaaa atcaataaaa ggaacactgg ttatgtacaa gaaatacttg
    28921 aaccagtgaa tgcacaggaa ggaaatcaac tctctgttgg tacacttgta gcaaatggaa
    28981 tgacaactgg cgaaatgcct ttaggaacgg cttctatgga aaagcggggc gtcgctttag
    29041 aagtacctga gtggattagt gatcgctgta cgatgtgtaa tgaatgtgcc tttgtttgtc
    29101 ctcatgctgc catccgtcca tttttagcag atgaagagga aatggaagaa gcgccagaag
    29161 gatttatcgt gagagaaatg cgaggcgcag acggcgtaaa ataccgtatc caagtttcag
    29221 tggaagactg tacaggttgt ggtctgtgtg tagaggcttg tcccgcaaaa gaaaaagctt
    29281 tagtgatgaa gccttatgaa gaacagaaag aacaagctgt gaattgggct tttgcaatga
    29341 cattaagaca aaaagcaaat ccagtcaaag gaaagaatac tgtcttgtct acacaattca
    29401 atcaaccgct tcttgaattc tcgggcgctt gctcaggctg tggcgaaaca ccttatgtaa
    29461 aattattgac acaaatgttc ggtgatcgaa tgatgatcgc gaatgcgaca ggctgttctt
    29521 ctatttgggg cggtgcttct cctgcttctc cttatacgac aaatgaatgt ggtcaagggc
    29581 ctgcatggtc aaattcttta ttggaagata atgctgaatt tggttatggt atgcttctag
    29641 cggcacagac tcgtcgcgag gctttggcaa gttcaatcaa agaagtattg ccaaaagtat
    29701 cagaagaact acgagaattg atggaagact ggttggtaca catgtttgag agcgaaggaa
    29761 cgcagcaaag agcagcaaaa ctgcaagctg cgatcgaaag cgaacgatca attgtccctg
    29821 aactggagga tatatacaag agaaaggatc tattcgtaaa aaacagccaa tggatgattg
    29881 gtggagacgg atgggcttac gacattggtt ttggcgggat cgatcatgta cttgccagcg
    29941 gagcagacgt gaatattctt gttttggata acgaagtcta ttccaatact ggcggtcaaa
    30001 cctcaaaagc aacaccagct tcggcaatcg ctaaattttc ggctagtgga aagtatgctt
    30061 caaagaaaga tctaggaatg atggcgatga catatggaaa tgtttatgtg gcgcaaattg
    30121 cttcaggtgc caatcaaatg cagacgataa aggcttttga agaagcagaa aagtatcctg
    30181 gaccttcttt aatcattgcc tatacgcctt gtatcacaca tggtttgctt ggtggaatga
    30241 aagaatcgct taaagaagca aaagaagctg tttcttctgg ctattggtca ttatatcgat
    30301 ataaccctgc aatggtcgaa aaaaacaaga acccaatgac tttggactac aaaaaacctg
    30361 atttctctgc tatgcctgat ttcatgagga aacaagttcg cttttcctcg ctagagaacg
    30421 caaatccaaa tcttgcaaaa gctttatttg aaaagactat ccaagacgct aaaacacgtt
    30481 tttacaacta tgctgcactg acgggagaat tagaaaaaat caagaaacga cttgaaccag
    30541 aggaatctat cgatgtaccc gttaagacta gaaaagaaaa aacgacggac cttgaagcag
    30601 aagaaagaag agctgccaga gcagaacgac gtaaaaaaat ggaacaagct acaaaagaaa
    30661 aaaaggaaaa ataacagaaa aaatataatg aataattctc tgaagtttaa aaatatttat
    30721 tgcagagaaa aataaaacgc atacttgcaa ttttcctgaa aattatgcgt ttttctcaag
    30781 aaaaatacga gcagatcagc ctctaaaatt aaaacatatg atatactaga gaggaaatct
    30841 caaaagagaa gagaggcttt ttatgtcatt tcaaatcggg gaacttttta atttggacta
    30901 ttggcagcaa atgttttccg gtgacttgtt ctctctgaat tttttggtga acatacttga
    30961 tattctggtt gtctggtatc ttgtatacaa actgatccaa ctgctgcgag gcacaaaagc
    31021 gattcagctt ctgaaaggtg tagctatttt tattgttatc cgaatcgtag cggaaatcat
    31081 tggtctgcac accttgtctt ggctgatgaa ccaagtcatt acgtacgggg tgatagctgc
    31141 tatcgtgatt tttcagccgg aaatccggag aggactggaa catcttggac gcagttcgct
    31201 tttcaaacaa tcaaaaagcg aacagcagga agatgagaag atgatcttgt cttttgacaa
    31261 agccatccaa tatatgtcca agcgaaaaat cggtgcgcta attactatcg aacggcatac
    31321 tggattagat gagtatattg agacaggaat tgcattagat gcagatatca ctggagagct
    31381 gctgatcaat atctttattc ctaatacacc gctgcatgac ggtgcagtta ttgtaaaaga
    31441 aggaaagatc gcagtagcaa gcgcctatct tcctctatca gaaagtatgt tgattccaaa
    31501 agaattcggg actcgacacc gggcagctgt cggtataagc gaagtcagcg acgcgattac
    31561 catcgttgtc tctgaagaaa ctggggatgt cagcattaca ttagataatg aactgatggc
    31621 tggcttatcc cagcaagaat atttggcaat tttgcgtaga gaactgattg ctgaagagaa
    31681 aacaaaaaac aagaaaaacg tgattcaatc tttcctagac ggtatgacta agggagggga
    31741 tcgcaaatga tctcaaaaga gaaacggaca agcattcttt acagttttat tgcattgctg
    31801 ttcagtattg cgctgtactt caatgcaaat ggccagtccg ttccaaatac gctttctgga
    31861 aatgaagcgt ataatcaaac agttactggg gtgccaatca agatttctta tgattcaaag
    31921 cgctactata tccatggata tgaaaatgca gtgactgtca aactttccag tgcaaaccga
    31981 gttcagttga atgcagaggc aaacgaagat acacggatgt tccgcgtcac agcagatatc
    32041 actaagctgg gcgaaggaac acatgaggtt ccgctaaaaa ttcaaaattt gagcagtgct
    32101 gtcacagcaa agatcgaacc atcgactatt acagtaacgg ttgagaaaaa ggtaataaaa
    32161 gatttcgatg tggaaacgtt gattccttca acgttcacac catctggata tgaacttgat
    32221 gatacttccg ttagtcctaa aaaagtctct atcactacag gtgacaaaac attggcagaa
    32281 atcaaacgag tagtagctga tgtggacgct tcgatggtca cagatgatgg gattaatagt
    32341 gaggtcccaa tacaggcgct gaatgcagca ggggaagtat taagtatcgt ctctgatcca
    32401 gtgcaagtaa cagtgagagc tgattcgatc aagccaagca agtcggtacg actttatggg
    32461 atacagcaag gaacaccagc tgccggggta gaaagctatg atttcagttt ttcaaaactg
    32521 gaagcagaag taagcggctc tagcgatttg cttgcatcga tcggtgacag tattgctgta
    32581 ccgatcaatg tctcaggtat caatcatcga acaactcgta aaattgaaat accagtagaa
    32641 gaggggttaa gtatcaagcc cgaatcagtt agtgtggaga ttacacccgt gttgcaaacg
    32701 tcaagcagta gctctgcttc gacgagcagt cggacacaag aaaatacaag tacgagtaga
    32761 agtatttcat ctgctgattc aggaacggaa ccatcgacaa caaccatttc ttccagttcg
    32821 gaatctggga caagcagctc gaccacaagt acagaagaaa catcagaaac aagcgaatca
    32881 acacaaatga gcagaacaaa ttcctcagaa aattaagtta aaggagtaat tttacaacta
    32941 tgggtaaata ttttggaaca gacggcgtac gcggtgaagc caacaaggaa cttacgccag
    33001 aacttgcatt taagctggga cggtgcggag gttatgtcct aagccagcat gaagaagaag
    33061 gaaaacgccc acgcgtgtta gtagggcggg atacaagaat ctcaggtcaa atgttagaag
    33121 aagcgctgat ttcaggactt ttatcggtgg gtatcgaagt gttccagcta ggtgtgatct
    33181 ctacaccagg tgttgcttat ctgacacgtt tgcaaaaagc aagcgcaggg gtcatgattt
    33241 ctgcttctca taatccagca caagataatg gaatcaaatt tttcggtgca gatggtttta
    33301 aactagtaga tgaccaagag ctagaaattg aagcattatt agatgctgaa gtggatgaat
    33361 tgcctcgtcc atcagctgaa ggattgggaa ctgtagaaga atttccagaa ggcttattga
    33421 aatattctca attccttgta caaacgatca acggtgacct ttccggtttg accatttgtg
    33481 tcgatgcagc aaacggagca acttcaacaa gtgttaatcg tttgtttgcc gatcttgaaa
    33541 cagattttta taccatgggc acaaatccag acgggttaaa tatcaatgat ggcgtaggct
    33601 ctacccatcc agaacgttta gctgagatgg tcgttgaaaa aggagcagat gctggactag
    33661 ctttcgatgg cgatggcgat cgtattattg cggtggatga acttggaaac attgtcgacg
    33721 gtgataaaat catgtttatc tgtgctaaat acttggcaga aaaaaatcga ttgaaaaaag
    33781 atacgatcgt tacgactgtc atgagtaact taggattcca caaagcggtg gaaggaatcg
    33841 gtttgaaaga tgtcgttaca caagttggtg atcgttacgt tgtagaagaa atgcgcaaaa
    33901 acgattataa ctttggcggc gagcagtctg ggcacatgat tttcttagat tttaacacaa
    33961 ctggagatgg gatgctttca ggaattcagt tactgaatat catgaaacag acaggtaaga
    34021 aattatcaga gcttgcagca gaggtaacaa tctatccgca aaaattagtg aatatccgcg
    34081 taagtgataa aaacggtgcg atggatgttc cggcaatcaa aaaagtgatt gaagaggcag
    34141 aagctgaaat gggatcagaa ggaagaatcc tagttcgtcc ttccggtaca gaaccattac
    34201 ttcgagtgat ggcagaagcg cctactgatg agaaagttaa ttactatgtc gataaaatcg
    34261 cggcagtagt caaagaagaa atcggactgg attaagagat attttcataa aaaataaaag
    34321 aacaaggacc agtgtcagat gtctgacact ggtccttgtt cttttattat
//
LOCUS       DADVXB010000012        33294 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.012, whole genome shotgun sequence.
ACCESSION   DADVXB010000012 DADVXB010000000
VERSION     DADVXB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.012"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="KB902_000445"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="KB902_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBB6807299.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="KB902_000446"
     CDS             complement(2020..2922)
                     /locus_tag="KB902_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6807300.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="KB902_000447"
     CDS             complement(2919..3611)
                     /locus_tag="KB902_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBB6807301.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="KB902_000448"
     CDS             complement(3654..4295)
                     /locus_tag="KB902_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6807302.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="KB902_000449"
     CDS             complement(4333..4647)
                     /locus_tag="KB902_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807303.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="KB902_000450"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="KB902_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="KB902_000451"
     CDS             complement(5984..6916)
                     /locus_tag="KB902_000451"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBB6807304.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="KB902_000452"
     CDS             complement(6913..7689)
                     /locus_tag="KB902_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBB6807305.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB902_000453"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB902_000453"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBB6807306.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB902_000454"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB902_000454"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBB6807307.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="KB902_000455"
     CDS             complement(12014..13294)
                     /locus_tag="KB902_000455"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBB6807308.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="KB902_000456"
     CDS             complement(13313..14239)
                     /locus_tag="KB902_000456"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBB6807309.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="KB902_000457"
     CDS             complement(14252..15535)
                     /locus_tag="KB902_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBB6807310.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB902_000458"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB902_000458"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBB6807311.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="KB902_000459"
     CDS             complement(16323..17234)
                     /locus_tag="KB902_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6807312.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="KB902_000460"
     CDS             complement(17231..17695)
                     /locus_tag="KB902_000460"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBB6807313.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="KB902_000461"
     CDS             complement(17700..18398)
                     /locus_tag="KB902_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6807314.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="KB902_000462"
     CDS             complement(18385..18771)
                     /locus_tag="KB902_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807315.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="KB902_000463"
     CDS             complement(18918..20588)
                     /locus_tag="KB902_000463"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBB6807316.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="KB902_000464"
     CDS             20771..21004
                     /locus_tag="KB902_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBB6807317.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="KB902_000465"
     CDS             complement(21103..21534)
                     /locus_tag="KB902_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBB6807318.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="KB902_000466"
     CDS             21613..22026
                     /locus_tag="KB902_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBB6807319.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="KB902_000467"
     CDS             complement(22064..23212)
                     /locus_tag="KB902_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6807320.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="KB902_000468"
     CDS             complement(23334..23930)
                     /locus_tag="KB902_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6807321.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB902_000469"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB902_000469"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBB6807322.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDAPTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="KB902_000470"
     CDS             27160..27591
                     /locus_tag="KB902_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6807323.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMEKSLA"
     gene            complement(27636..28985)
                     /locus_tag="KB902_000471"
     CDS             complement(27636..28985)
                     /locus_tag="KB902_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6807324.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="KB902_000472"
     CDS             complement(29055..30218)
                     /locus_tag="KB902_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6807325.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="KB902_000473"
     CDS             30347..30670
                     /locus_tag="KB902_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807326.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRRVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="KB902_000474"
     CDS             complement(30853..32202)
                     /locus_tag="KB902_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6807327.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="KB902_000475"
     CDS             complement(32271..33224)
                     /locus_tag="KB902_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBB6807328.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
BASE COUNT         9486 a         7294 c         5870 g        10644 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acgttacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaacg atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttggcgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta ttaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atggaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaat ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg ccgcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctct
//
LOCUS       DADVXB010000013        32881 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.013, whole genome shotgun sequence.
ACCESSION   DADVXB010000013 DADVXB010000000
VERSION     DADVXB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.013"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(58..450)
                     /gene="rpsI"
                     /locus_tag="KB902_000476"
     CDS             complement(58..450)
                     /gene="rpsI"
                     /locus_tag="KB902_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6807329.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(466..909)
                     /gene="rplM"
                     /locus_tag="KB902_000477"
     CDS             complement(466..909)
                     /gene="rplM"
                     /locus_tag="KB902_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBB6807330.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(1428..1895)
                     /locus_tag="KB902_000478"
     CDS             complement(1428..1895)
                     /locus_tag="KB902_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6807331.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(2015..3553)
                     /locus_tag="KB902_000479"
     CDS             complement(2015..3553)
                     /locus_tag="KB902_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBB6807332.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            3633..4319
                     /locus_tag="KB902_000480"
     CDS             3633..4319
                     /locus_tag="KB902_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBB6807333.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEVLCGGLFAWFFTFSSARNFSTFIWVLS
                     ALLFSLMDLFYFMVHSHTLFCSWAVLWIFWLQDGVFQWQSVLLTFIVGGACLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFFVYFICHKKKMEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(4520..5047)
                     /gene="msrA"
                     /locus_tag="KB902_000481"
     CDS             complement(4520..5047)
                     /gene="msrA"
                     /locus_tag="KB902_000481"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6807334.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYSD
                     EEERSIAERSKQELQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFIRRHWGGKK"
     gene            complement(5131..5808)
                     /gene="pgmB"
                     /locus_tag="KB902_000482"
     CDS             complement(5131..5808)
                     /gene="pgmB"
                     /locus_tag="KB902_000482"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6807335.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVIANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWYL
                     SEAVSRI"
     gene            complement(5805..6935)
                     /locus_tag="KB902_000483"
     CDS             complement(5805..6935)
                     /locus_tag="KB902_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6807336.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQR
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFIFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSGAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKATDFGISAV
                     FPILPAAVPLEEALHQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(6935..9118)
                     /locus_tag="KB902_000484"
     CDS             complement(6935..9118)
                     /locus_tag="KB902_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6807337.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERVLDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(9115..10140)
                     /locus_tag="KB902_000485"
     CDS             complement(9115..10140)
                     /locus_tag="KB902_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6807338.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELVAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNYLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKNVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIHNLVENLYRSAE
                     TGEVITL"
     gene            complement(10185..11012)
                     /locus_tag="KB902_000486"
     CDS             complement(10185..11012)
                     /locus_tag="KB902_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6807339.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKKTGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(11009..12076)
                     /locus_tag="KB902_000487"
     CDS             complement(11009..12076)
                     /locus_tag="KB902_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBB6807340.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSGEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKTAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVQGGEQ"
     gene            complement(12102..12938)
                     /locus_tag="KB902_000488"
     CDS             complement(12102..12938)
                     /locus_tag="KB902_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6807341.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISSLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(12935..13804)
                     /locus_tag="KB902_000489"
     CDS             complement(12935..13804)
                     /locus_tag="KB902_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807342.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNLDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(13874..15157)
                     /locus_tag="KB902_000490"
     CDS             complement(13874..15157)
                     /locus_tag="KB902_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6807343.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(15170..16855)
                     /locus_tag="KB902_000491"
     CDS             complement(15170..16855)
                     /locus_tag="KB902_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBB6807344.1"
                     /translation="MYTKLLQAIYRDSDLAEKTASMIEQKVSDYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIVDEAAPGTVLITETNVPHKD
                     NISYFGDGRNEAQMVYQFSLPPLTLHAIRSGNTSKLKEWLETINFTSKKTTFFNFLAS
                     HDGIGLNPIRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            17130..18155
                     /locus_tag="KB902_000492"
     CDS             17130..18155
                     /locus_tag="KB902_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807345.1"
                     /translation="MKPTIYDIANKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQTGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(18753..22427)
                     /gene="rpoC"
                     /locus_tag="KB902_000493"
     CDS             complement(18753..22427)
                     /gene="rpoC"
                     /locus_tag="KB902_000493"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBB6807346.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(22485..26102)
                     /gene="rpoB"
                     /locus_tag="KB902_000494"
     CDS             complement(22485..26102)
                     /gene="rpoB"
                     /locus_tag="KB902_000494"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6807347.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            26830..27798
                     /locus_tag="KB902_000495"
     CDS             26830..27798
                     /locus_tag="KB902_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6807348.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLGEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKKPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            27816..28724
                     /locus_tag="KB902_000496"
     CDS             27816..28724
                     /locus_tag="KB902_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807349.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTET
                     GLAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGT
                     IVIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFV
                     LVICLSFPQIQQKFHLPQKKKGGSVK"
     gene            28721..29527
                     /locus_tag="KB902_000497"
     CDS             28721..29527
                     /locus_tag="KB902_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807350.1"
                     /translation="MNDVLTLENLHHAFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLARLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GNRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            29663..30652
                     /locus_tag="KB902_000498"
     CDS             29663..30652
                     /locus_tag="KB902_000498"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBB6807351.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKATSVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQEMSLSSGEISLTSIRTQ"
     gene            complement(30969..31493)
                     /locus_tag="KB902_000499"
     CDS             complement(30969..31493)
                     /locus_tag="KB902_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBB6807352.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRRAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            31780..>32881
                     /gene="scm"
                     /locus_tag="KB902_000500"
     CDS             31780..>32881
                     /gene="scm"
                     /locus_tag="KB902_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6807353.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVDSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTGLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSASSDSTDTTSTT"
BASE COUNT         9223 a         7081 c         6197 g        10380 t
ORIGIN      
        1 aaaagacact ttccaaataa ttgaaaagtg tcctgaaata ttgatataaa aagaatatta
       61 acgttttgag aattgtgaag ctttacgagc ttttttaaga cctggttttt tacgttcgac
      121 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
      181 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
      241 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
      301 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
      361 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
      421 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
      481 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
      541 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
      601 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
      661 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
      721 cactttgtct gcattgatga cgatgacgaa atcgccagta tccaaatgag gtgtgaaagt
      781 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
      841 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
      901 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
      961 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     1021 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     1081 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     1141 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     1201 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     1261 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     1321 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     1381 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     1441 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     1501 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     1561 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     1621 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     1681 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     1741 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     1801 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     1861 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     1921 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctaagaac
     1981 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     2041 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     2101 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     2161 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt cgccagccta
     2221 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     2281 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     2341 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     2401 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     2461 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     2521 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     2581 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     2641 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     2701 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     2761 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     2821 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     2881 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     2941 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     3001 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     3061 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     3121 gttggctatt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     3181 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     3241 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     3301 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggta
     3361 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     3421 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     3481 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     3541 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     3601 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     3661 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     3721 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     3781 ttctctcgat catcgtccaa cgatttcgct gtcgctattg ccggtgtcgg ttgcccttct
     3841 actatttgtt ggcagaagtc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     3901 ccgcaagaaa tttttcgacg ttcatttggg tgctttcggc tttgctattt tcgttgatgg
     3961 atttatttta cttcatggtc cattctcaca cgctattctg ctcctgggca gtcttatgga
     4021 ttttttggtt gcaggacggc gttttccaat ggcaaagtgt tctgttaacg ttcatcgtag
     4081 gcggtgcatg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     4141 tttcttggag tggtggcttg tctctggaag agttgcttca gatcttgttt cttgctagtc
     4201 tgtttggaat atccgttttt tttgtttact ttatctgtca taaaaaaaag atggaaaaac
     4261 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     4321 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ctaccaaatc
     4381 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     4441 ctgaccctcg gtattagctc aaaatgctga tttcacaatc tctgatatac ggtattccag
     4501 aagtagcttt ttcggcttct tatttcttgc cgccccaatg tcgacgaatg aaaccggcac
     4561 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     4621 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     4681 cgaatcgccc gctgtcttgc aattcttgtt ttgaacgctc tgcaatgctt cgttcttctt
     4741 catcactata gtagatcact ggtcgataag aatcaccacg atcagcgaac tgtcctaacg
     4801 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     4861 ctgggtcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     4921 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     4981 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     5041 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     5101 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaata
     5161 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     5221 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     5281 gccagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     5341 tcctttgaga aaaacttccg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     5401 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     5461 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     5521 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     5581 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     5641 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     5701 gaatggaatg gacagctggt tagctataac cagccacgct tcgtaatgat aacgagctgt
     5761 gtctacaaga acgccatcta aatcgaatag cgctgctttg attttcatcg attacctcct
     5821 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtacgatg cagattatca
     5881 gtggcttgat gtaaagcttc ttctaaagga acagctgcag gaagaatcgg aaaaacggcc
     5941 gaaatgccaa aatctgttgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     6001 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     6061 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     6121 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     6181 aatagtcctg cacccatacc accaccagca ccacttcccg atgcctcgat tacttgaggg
     6241 gcaaatctca tgtaaaaatc atgcatagct tggtcagcta ctgctagttc attttctttc
     6301 aagccttttt gtggtccgaa aataaaagaa gcgccttctt ttccgcataa aagattagta
     6361 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     6421 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     6481 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     6541 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     6601 actcctcgcg tggataacct aagtggctgt cgttggttta gtgggacatc tttcaatccg
     6661 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     6721 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     6781 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     6841 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     6901 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     6961 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     7021 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     7081 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
     7141 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
     7201 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
     7261 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
     7321 gaatcgcttt actcaacgat gagtcgtgga tcgttttgtt ttcatagtaa tgcaaattct
     7381 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
     7441 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
     7501 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
     7561 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
     7621 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
     7681 tataatgcgc cagatagttc gtatatgcat tattgtcaat atattctgtg tattcatctg
     7741 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
     7801 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
     7861 ttgcttggac atactcttga acggcataag caaggtctgc actgatatgg tgttctgcgg
     7921 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
     7981 tctcttcctg accagtgtgt gcgctctccc atgggaaaag tgcaccttga tagtgataat
     8041 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
     8101 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
     8161 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
     8221 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
     8281 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
     8341 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
     8401 acgggtctgt ttgctgaaga gaggtagaga gtacgatgat cttctctaga gtaaaggacg
     8461 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
     8521 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
     8581 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
     8641 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
     8701 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
     8761 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
     8821 gctctcccat ttctaaatct agtacccgct catatgcaag aactttcatc gtctcaagag
     8881 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
     8941 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
     9001 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
     9061 tctgactcgc atacttattg atatactcta aatcaaattg tttttcttct actttcataa
     9121 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tatggatgac
     9181 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
     9241 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
     9301 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
     9361 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
     9421 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
     9481 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
     9541 gtacgcccga acgtttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
     9601 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
     9661 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
     9721 aacatcaaga taattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
     9781 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
     9841 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
     9901 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
     9961 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    10021 tcgctggctg actggatcaa ccacagcgac caattctaag acatctgatc ttttttgata
    10081 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    10141 ttatttctcc ctcctttgct tatttactta ttgtttttct ttctctattc tttctctaaa
    10201 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    10261 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    10321 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    10381 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    10441 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    10501 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    10561 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    10621 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    10681 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    10741 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    10801 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    10861 gtttttttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    10921 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    10981 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tccttgtact tgaacaccca
    11041 ttttgatact ttcttctggg tgctgatcta cataacgcat gtaagcttct gcgctttctg
    11101 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    11161 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    11221 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    11281 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    11341 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    11401 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    11461 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    11521 cgatggtagt ggcacctgct tttttagcta attgaatcgc aatttgtccg atagcgccta
    11581 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttctcggata ccacctaaag
    11641 cgaattgagc aggatcgtaa catactgcag ttttccattg atccaaccga tcaagtttac
    11701 gtagtttata attatcaaca ccgtttgtaa tcagtgtttc acgaatgggt ccataagtgc
    11761 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    11821 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    11881 ttggcaagaa taggcgccat tctcctgaaa attcttcatc gataaatgga cttaatcctc
    11941 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    12001 cgttcttttc gatctcgcgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    12061 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    12121 tcgactaaat cacctttaat gaatcgttca gataacgcat acataatgat gactggtaaa
    12181 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    12241 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    12301 aaataatcat tccacgaaac cataaaacaa taaacgaaga cagaaatgat tccagaaata
    12361 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    12421 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    12481 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    12541 ctggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaaccgtg
    12601 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    12661 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    12721 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    12781 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    12841 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    12901 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    12961 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    13021 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    13081 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    13141 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    13201 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    13261 aaaatgaaat aaacgcatac ggatagtatc tccagatcgc aaacaaaacg accataaaga
    13321 agctagcaac tggctgatcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    13381 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    13441 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    13501 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    13561 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    13621 tttcaagata attgcttaat ccgataaaaa cggcgtctaa gttaggattc agcggcatat
    13681 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    13741 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    13801 tcattgaaac ctccccctga taatctgcca atagctatct gattttttcg aacaccattg
    13861 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    13921 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    13981 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    14041 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    14101 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    14161 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    14221 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    14281 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    14341 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    14401 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    14461 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    14521 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    14581 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    14641 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    14701 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    14761 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    14821 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    14881 ccattacttc tggtaattta ccggaacgag ctaacgtaac gattttcgta ttgaacgctg
    14941 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    15001 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    15061 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    15121 tagctagcag acaggtagta acaataattt ttttcatttt ttccacctct tattttatta
    15181 ttttcagcca catatattca tacggctgga atatcaactt tcgttcttga ctgcaatgga
    15241 taatttgtcc agaaaacagg tctaggtaat ctccttttgg taaaagataa cctgctgatt
    15301 gattggaaaa attatggata actaagactt tctcttcctt cgcttcgcga ataaaactga
    15361 taaaagaatc agctgagtcc agtaagtaaa tcaaactatt cggatggaag gctttttctt
    15421 tttttcgaat agatagcatc tgggtcaatt caccatatac tgctgttctt aatggatctg
    15481 tctgcaactc tttctcaata tctgctaaca aaaatttttg ccgattgatt tttcgattct
    15541 ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc cagcacactt tgaatataaa
    15601 ttgccggcac gcctggtaaa gttaccaaaa atgaatgagc tgctaaaaag cgtttgcttc
    15661 tccattccgt cgtatctgtt ggagaactta acgcatctag atacgtagcg tttatctcat
    15721 atggactggt cgttccatct gggtttttct tgtagtttac tcgggcaccc tctttcttca
    15781 gctgttccac taattcaagg atcgtttttt ccggcagaat acctcttatc gggtttaatc
    15841 cgattccgtc atgggaagct aaaaaattaa aaaaggtcgt ttttttcgat gtaaaattga
    15901 ttgtttctaa ccattctttc aacttacttg tatttcccga gcgtatcgcg tgaagagtca
    15961 aaggtggcag tgaaaactga tagaccatct gtgcttcatt cctgccatcg ccaaaataac
    16021 taatattatc tttgtgtggc acatttgtct cggtgatcaa taccgttcct ggagctgctt
    16081 catcaacgat tgcacggaat aactgaataa tcttatgcgt ttctggcagg tgtatacaag
    16141 aagttcctag ttctttccat aaaaacccca cagcatctaa acgaataaat gaagcgcctt
    16201 tttctaggta aaacaaaaga atatcgatca ttttcaataa aacttctggg tttttaaaat
    16261 tcaaatctac ttgatcttcg ctaaaagtcg tccatacatg tttttctttc ccgtttttgt
    16321 cgatgaaagt tgtaagtagt ggactagtcc ttggtctagt cacgctgctt gtatctgtat
    16381 ccagtggcaa atcaataaaa aaatctttgt acgtatcatt caagtttaaa tattcctgaa
    16441 accaagtact ttcggcagac atatgattgc agacaaagtc gaacattaac cgtgtttcgc
    16501 ttctcatttc ttctatatct tcccatgtgc ccaaacggtc gttgattgcc tgataattta
    16561 caacggagaa accatcatca gatgtatatg ggaaaaatgg caagaaatgt acaactctaa
    16621 atgtatctgc caaatacttt tgataaaatt tcttaaatgt acgcaaagtt ggttgctgct
    16681 cttcaaaaaa ttgatcccca taagtaatca agaaaatatc ttcttcgtcc caatgcagtt
    16741 tgcctgcctg gcctttcttc tgctgataat cactgacttt ttgttcaatc atagaggcgg
    16801 ttttctcagc caaatctgag tcgcgataaa tcgcttgtaa aagttttgta tacatcggat
    16861 tcccctttct tttttgggag cgttcccaac gatttgatca tattatggaa aacgcttact
    16921 gtcaatagca tttttttaaa taattttgat atacaaaaaa atacaaataa gaaagcttat
    16981 gtatcaatag ttaatagctt cttaaaaaaa tatggtctct catgatcatg caagctattc
    17041 ctaaattttc aaaatcatag acaaaaaaga atgtctattg tactatggaa ttattctaaa
    17101 acgctcccaa aaaggaggtg catataaaat tgaaacctac tatttatgac attgcgaaca
    17161 aagccaatgt ctccaaatca actgtctcca gagtattaaa taaccagcca aatatctctg
    17221 ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt gaattatgaa ccgagcaaaa
    17281 ttgcaagagg actgtcagga aatggttttg acgcgattct agcattatct catcgtactt
    17341 ctcatacgac ctatggcaat cctttttttt cagatgttat tcaatccatt tctgccgttt
    17401 ctgaacaaaa taacttcgac ttgattctac aaacggcaaa aacaccagaa gaagagctag
    17461 aaaaatgcgc gaaaaagatc caagaaaaaa tgattcgagg aattattatt ttaagctcta
    17521 cgatggatga aacacttctt tttgaattgg atcaatacaa tattcctatt gtggtaatcg
    17581 gaaaagtcgg aaacgactac acgaacatct actcagtgga cacggataat ttccaggata
    17641 gttacgattt ggtggaaaca ctgatcaaga atggacaccg tcatatcggc tgtctccatg
    17701 ctccgacaga agtttatgta tccaatgatc gtctcaatgg ttaccgtcaa tgcttatttg
    17761 atcatcacct agatatccgt aatgaatgga tcatagacgg cggctttcgc ttagaagaca
    17821 gcatggcagc aatgaatgat ttaatgaagt tgcgagaaag accaactgcg attttttcta
    17881 ccgatgcatt aaaatcattg agtatttaca aagtggcaga acaaactgga aagcagatac
    17941 ctgatgatct ttcgatcgca ggattcagtg atcccttatt gtcctcccta ttttcgccac
    18001 agctgactcg gatagacatt ccaacaaatc agttaggaat caaagccaca gaacttttat
    18061 tccaattgat ccatcaccaa tacccagaag aaaaaagaat cattctttca accgagatta
    18121 ctctcacaga ttcgatccaa caacaagaaa tgtagggcag atttataaaa gaacagaaac
    18181 actgaggata agtcagttac tctgttcttt tttcaatcac tcatcctcca ttaccccctc
    18241 ccggtatttt agcggatttt tctttatttt ccatctgttt tagatagctg tggataacta
    18301 taatgtttgt gttaaactat tttttccaca ggcaagaaaa agttgtcttt tcagccacgt
    18361 tgtgtataag tttttaaagt tcattttttc aaacttattt acccttattt caatccatgt
    18421 tatttgggga tacttatctc taaaacataa atagaataac tagacatgtc tactggtttt
    18481 gttgtattcg aggaactatt cactaatagc tagcaaaata ttaaaaataa ccgctctatc
    18541 ttcccatgaa tttattttgc attcaaaaaa tgatctatct ttatttttat tgattgactt
    18601 ctctgggaag atgatcgttc cgatacctta atgggatacg aaccgatgtt gtaagatcct
    18661 ttcccacttt tcttctagtt agacaaatta ttttagacaa acaaaaaaag aggttgtgac
    18721 aataatttgt cacaacctct tttgtaaaat atctattttg tttgattgtt cattgcgtct
    18781 tctgcagcca tttgtgcttc aatatctgaa atactgtaga cattttcgct tgctacaccg
    18841 acttcttttg gttccatgtc acggtaacgt tgcataccag taccagctgg gatgatctta
    18901 ccgataataa cattttcttt caaaccaaga agaggatctt tcttaccgcg gatcgcagca
    18961 tccgtcaaga cacgagttgt ttcttggaat gatgcagcag ataagaaact atttgtttct
    19021 aatgatgctt ttgtgatacc tagcaagaca ggtcgagaag ttgcaggaac gcctcctgag
    19081 actagcgtat tgtaattttg atctttaaag tctgcgatgt ctaataatgt acctggtaag
    19141 atatctgtat cacctggatc cattacacga actttacgca gcatttgacg aaccattact
    19201 tcgatatgct tgtcgccgat ttctacccct tgcatacggt aaacacgttg tacttcacga
    19261 agcaagtagt tttcaacaga taatacatcg cgaacttgca acaattgttt tggatcgatt
    19321 gatccttctg tcaatggcgc accacggtgg atcatatcgc cttctgctac tttcatacgt
    19381 gctgtataag gaacagtata cgtacgtgta tctgtttttc ctttgattgt tacttctttg
    19441 gtacgtgttg caggatcttc tgagatatcg atgacatccc ctgttacttc tgtgatcact
    19501 gcttgccctt tcggattacg tgcttcaaag atttcttgga cacgaggaag accttgagtg
    19561 atatcgtctc cggcaacccc acccgtatgg aatgtacgca tcgtcaactg agtaccaggt
    19621 tcaccgattg attgagcggc gatcgtacca actgcttctc cgacttcaac gtcagagcca
    19681 gttgcaaggt tgcgtccgta acaatgtttg cagacaccat gttttgtatt acatgtgaag
    19741 acagaacgga ttgtcactgt ttcgacacct gcatcaacga tttgttttgc gatgtcttcg
    19801 gaaatcaatt ggtttcctgc aatgatcaat tcatttgttt caggatgacg tacttcttta
    19861 cgagtgtaac gtcccactaa acgatcttct aatgattcga tgatttcatt tccttcacgg
    19921 attgcttgga tttcaagacc tcggtcagta ccgcaatctt cttcacggat gattacatct
    19981 tgggccacgt caaccagacg acgagtcaag taacctgaat cggcagtctt caaggctgta
    20041 tcggtcatcc ctttacgagc cccgtgagtt gagataaaca tttccaagac ggatagtcct
    20101 tcacggaagt tcgaaatgat tggcaattcc atgattcgac cattaggagc ggccatcaaa
    20161 ccacgcattc cggcaagctg tgtaaagttg gaaatgttcc cacgagctcc agaatcagac
    20221 atcatgaaga ttgggttttt cgcttccaaa ccttccatca gtttttgttg gatgctgtct
    20281 tttgcagcgt tccaaacagc aatgacacgt tcataacgtt cgtcatctgt aatcagacca
    20341 cgacggaatt gttttgtaat agtttcaact tgtttatggg cattttcaat gatttcttgt
    20401 ttttcattca gtacactgat gtcagcgatc cctactgtga taccggcatg tgttgaatgt
    20461 ttatacccta agtctttcat acggtcaagc atcttagaag tttctgttac tttgaatcgt
    20521 ttgaagactt ctgcgatgat gtttcctaag tttttcttct tgaacggtaa tactaattct
    20581 tgctctttga tatgtgcagg aatatcagta ccagcttcaa caaagtattt gtccggtgtt
    20641 tggacggtca agttgaagtc tgttggttca ttcagataag ggaattcagg aggcatgatc
    20701 tcgttgaaga tgatcttacc aactgttgtg atcatcgtac gttctttttg ccattcagta
    20761 aatggttttt cacctaatga gttagggttc acaccgatac gtgaatgtaa atgaacatat
    20821 ccgttgcgcc atgcgataac ggcttcgttt tgatctctga agaccattcc ttcgccttcg
    20881 cgtccttctt cttccattgt caagtagtag ttacctagaa ccatatcttg agaaggagta
    20941 acaactggtt taccatcttt agggttcaag atgttttgag cagctaacat caacatacgt
    21001 gcttctgctt gtgcttcttc attcaatgga acgtggacag ccatttggtc tccatcgaaa
    21061 tcggcattat aagcttcaca tacaagtgga tgcaaacgga ttgcgcgtcc ttgtactaaa
    21121 actggttcga atgcttggat accaagtcgg tgaagcgtag gtgcccggtt cagcaatact
    21181 gggtgttcct tgattacgtc ttctaagaca tcccatactt cgtcttcttg acgttcgatt
    21241 ttacgtttag cgtttttgat gtttgaagct agttcgcgtt gaacaagctc acgcatcacg
    21301 aatggtttga ataattcgat agccatttct tttggaagtc cacattggta catcttcaag
    21361 aaaggtccaa caacgataac ggaacgaccg gagtagtcga cacgtttacc tagcaagttt
    21421 tgacggaaac gaccttgttt ccctttcaac atatgagaaa gagatttcaa tgggcggtta
    21481 cctggtccag taactggacg tccgcgacga ccgttatcga tcaatgcatc tactgcttct
    21541 tgcagcatac gtttttcatt ttgaacgatg attccaggtg cattcaagtc taacaaacgt
    21601 ttcaaacggt tattacggtt gattacacga cggtaaagat cattcaagtc acttgttgca
    21661 aaacgtccac cttctaattg aaccattggg cgtaaatctg gtggaataac agggataacg
    21721 tccataacca tccagcttgg ttgatttcct gaagcgcgga atgcttctaa aatatccaaa
    21781 cggcggattg cacgtgtacg tttttgtcct tgtgcagatt tcaattcttc tttcaattcg
    21841 gctgcttctg catctagatc aacattatca agtaattgct tgatcgcttc tgcacccata
    21901 gcagcttgga attcttgtcc atattgttca cgtttttcgc gatattcgcg ttctgtcaac
    21961 aattgttttt tctctaaatt cgtatttcct ggttcgatga ctacatatga agcaaaataa
    22021 atgatttctt ccaaagcgcg tgggctcatg tctaatacaa gacccatacg tgaaggaatc
    22081 cctttaaagt accagatatg tgaaacagga gctgctaatt caatatgtcc catgcgttca
    22141 cggcgaactt tcgaacgagt aacttccact ccgcatcgat cacaaacgat tcctttataa
    22201 cggatacgtt tgtattttcc gcaggcacat tcccagtctt ttgtaggacc aaaaatccgc
    22261 tcacagaaca acccttcgcg ttcaggtttt aaggtacgat agttaatcgt ctcaggtttt
    22321 tttacttcac cgtaagacca gcttctgatt ttttcgggag aagccaaacc tatttgcata
    22381 ctttcgaatt tatttacatc gatcaaaagg ggttccctcc atttcattta atggcaaacc
    22441 gcaagacggc tgatcttcga ccgccttgca gctcatagac cggattagtc taaattatct
    22501 tctgcggttt caaagttttg gatgacatcg tctttttcat cttccacttg ttcagcagct
    22561 ttcttttcta attctttggc agtttgctgt tcggcaaatt ttgtcaaagc atcaacagtg
    22621 atcaaatcgt cgtcttcatc gtccatgtcg cgaagttcga tctctgtttc ttcgatatcc
    22681 aagacacgca tgtccagacc tagtgattgc aattctttca ccaatacgcg gaatgattcc
    22741 ggtacacctg gttttggaat tggttcacct ttgacgattg cttcgtatgt tttcacacgt
    22801 ccgactacgt catctgattt gtatgtcaag atttcttgta aagtataagc cgcaccgtaa
    22861 gcttccagtg cccatacttc catttcacca aaacgttgtc caccaaattg agctttacct
    22921 cccaatggtt gttgtgtaac caatgagtaa ggtccgattg aacgtgcatg caatttgtca
    22981 tcgaccatgt gagcaagttt gatcatgtac atcacaccga cagacacacg tccatcaaat
    23041 ggttcacctg tacgtccgtc gtacagaaca gttttcgcat cgctggccat accggcttca
    23101 cgaactgttt cccatacgtc ttcatcactt gcaccatcaa atactggcgt tgctacgtgg
    23161 atacctaact gacgtgcagc catacccaag tgtaattcca atacttgccc gatgttcata
    23221 cgtgaaggca cccctaaagg attcagcatg atatcgattg gtgttccatc aggtaggaat
    23281 ggcatatctt cttccggcat aatacgggat acaacccctt tatttccgtg acgaccggcc
    23341 attttatccc cttcatggat tttacgtttt tgaacgatat aaacacgaac taacatgttt
    23401 acgcctggtg acaattcatc tccagcttca cgagtaaaga ttttcacatc gtgaacgatc
    23461 ccgccgccgc catgtggtac acgtaatgat gtatcgcgga cttcacgagc tttttcgcca
    23521 aagatcgcat gcaatagacg ttcttctgca gataattctg ttaccccttt tggcgtgact
    23581 ttccctacaa gcaaatcgcc atcttggact tctgcaccaa tacggatgat acccatttcg
    23641 tctaaatctt ttaatgcgtc ttccccgaca ttagggattt cgcgtgtgat ttcttcaggt
    23701 cctaattttg tatcgcgggc ttctgattca tattcttcaa tatggataga agtgtatacg
    23761 tcatctttta ccaaacgacg gctcatgatg atcgcatctt catagttgta cccttcccaa
    23821 gtcatgaaac caactaaaac gttttggcct agagccattt cgccttgttc catagatggt
    23881 ccgtctgcca gagtatcccc tttttcgact ttctcaccca aatgaacgat tggacgttgg
    23941 ttgtagcttg ttccggagtt tgaacgacgg aattttgtta catcgtattt atctaatgca
    24001 ccgttgtcgc ggcgtacacg gatttcagaa gcatcaacgt attcaacgac accgtcatgt
    24061 ttacataaca aagcagctcc tgagtcatgc gctgatttgt attccatacc agtaccaacc
    24121 catggtgctt gaggattgat caacggcact gcttgacgct gcatgttggc acccatcaag
    24181 gcacggttgg agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac ggcaactact
    24241 tgtttaggtg atacgtccat gtagtctact ttatcaatag atacttctaa gttttcactt
    24301 tgagcacgag ccataacaac gtcttgagca aatgttccat cttcattcaa tgggctgttt
    24361 gcttgggcta cgatgtaatg gtcttcgatg tctgctgtca agtagtcgat ttggtcggtt
    24421 acacgacctg tttcgcggtc tacacgacga taaggtgttt cgataaatcc gaatttattt
    24481 actttcgcat aactggacaa actattgatc aacccgatgt ttgggccttc aggagtttcg
    24541 atcggacaca tacggccata gtgggagtag tgaacgtcac gaacttcata accggcacgg
    24601 tcacgagtca atccgccagg tcctaaggct gaaagacgac gtttgtgtgt caattcgcca
    24661 agaggatttg tttggtccat gaactgagac aactgagaag aaccaaagaa ttctttgata
    24721 cttgccacaa ctggacggat attgatcaat tgttgaggtg tcaatgtttc agtatcttgg
    24781 atcgacattc tttcacgaac cacacgttcc atacgtgcta gaccgatacg gaattggttt
    24841 tgtaaaagtt caccgactga acggatacga cggtttccta agtggtcgat atcatcgaca
    24901 ttgccgatac cttccatcaa gttcaagaaa tagctcattg aagcaatgat gtcggctgga
    24961 cgaaccgttt ttacagctgc ttctggatag ccgtttccga tcacatttac ttcacgttca
    25021 gggtctcttg gtgaaaatac tttgatgact tggacagtca ttggatctgt gaccacacca
    25081 tcttctgatg gatagtaagt cactgaattt agaccgttat caatgaaagg agctaatgtt
    25141 tccatgactt ggtgagtcaa gactgttcct ttttcaacga tgatctcgcc tgtttctgga
    25201 tcaactaatg tttcagctaa tgtcagattc aatagacgtg ttttcaaatc taattttttg
    25261 tttactttgt aacgaccaac gtttgctaag tcgtaacgtt ttggatcgaa gaaacgagca
    25321 ttcagcaagt tacgtgagct gtctgctgtt tttggttcgc ctggacgcaa acgttcgtaa
    25381 acgtctttca aaccttcttc tgttcttgag tcgcttgcgt ttttatgcaa gtctttttcg
    25441 actgtattgc gtaatgtttc gctgtcgccg aagatttcaa agatcgtatc atcggaacca
    25501 aatcctaacg cacgaactaa tacggttaaa ggaatcttac gtgtacggtc gatacgtaca
    25561 taagagatgt cttttgcatc agtttccatt tctagccaag cgccacggtt agggataaca
    25621 gtagaaccga atccttcttt tccgtttttg tcgacttttc catggaaata gacacctggt
    25681 gaacggacta actgagaaac gattactcgc tctgccccgt tgatgatgaa tgttccttgt
    25741 tctgtcatta atgggaaatc accgaagaat acttcttgtg ctttgatttc gccagtctcg
    25801 cggtttgtca aacgcaatgt tacatgtaat ggtgcagagt agtttgcatc atgcgcacga
    25861 gcttctgcta ctgtatactt tggttctttc aattcataat ctacaaattc caaagataga
    25921 ttgccattga agtcatcgat tggcaaaatg tcttcaaaca tttctctaag tccctcatct
    25981 aagaaccatt ggtaagagtc tgtttgaatt tcgatcaaat ttggtaattc caacacttca
    26041 ctgattcttg cgaaacttct acgttcgcga tgttttccgt attttactac gtgtccagcc
    26101 aagctcttca cccctctaaa atgtcattca aaaagactac ccgatcaatt gttacaataa
    26161 tatttcaaat attattttta ggtaacaaca gacatttttt gcggctttta ggcaaaaaaa
    26221 aaccaaaaat agaacattct cttgaaacct tacttcgtga gcttctactt ttgtttcctt
    26281 atattaaagc cgaaacggac aatatttcgt ttctgccttt tcttcatcag atagtttttg
    26341 caacttcata tactacactt attttctata aaagtcaaca cttcctggcg tttcttctgc
    26401 tttttcgcaa tattttctta atgttttcaa ttttatgttt tcaattatct gacaattctt
    26461 aattgacaga cctttttatc tcggttatac tttagaaaat tcattttgtg gaggaacttc
    26521 tatgcgaacc aacatcaacc aaatcgcacc aacacaactg aataactttt actttagcta
    26581 ctttagatag gtttgtattc atcatgatgg atacaaacgt taaacgacag tttgtatcta
    26641 tgatggctaa agaactttgt attgcagcaa aaagccacgt agacaaaatg ctaagtggct
    26701 gagcagtgaa aatacaaagt aaaagtatca agcattctac tttttcaatt tattttccga
    26761 cttttcaatc catttggaca ttttgtctga atggattttt tgtttcccaa aattaaggag
    26821 gaaaaagaaa tgaaaaaaaa tataatcatc ggattaggcg ctgccctgct actagcttta
    26881 ggaggttgcg cacaaaaaga caattccgca gaggcatcag atggacaaaa aacaattggc
    26941 gtattgcaac ttgtacaaca taactcgtta gatgctgcct ataaaggatt caaagaagga
    27001 ttaggagaag aagggtataa agaaggcgat aatctaacaa tcgattatca aaatgcccaa
    27061 aacaatcaag acaacctgaa aagtatgagt gagaaactcg tcaaagaaga tcctgatttg
    27121 ctacttggaa tcgccactcc agcagcacaa tctttattaa atgaaacaac cactatcccg
    27181 atgactgtca cagcggtcac agacttggaa caagcccatt tagtcacatc caatgaaaaa
    27241 cctggcggca atgtgactgg cacgacagat atggtgccaa tcgaaaaaca aatcggctta
    27301 ctgttaaata tcgtgccaga cgccaaaaca atcggcatca tgtataacaa cggtgaagca
    27361 aactctaaga tccaagctga tttggcagaa aaagaattga aaaaagcggg cgtcaaagtc
    27421 aaagtactga cagcaaattc cacaaatgat gtccaacaag tgacgaaaag tctagctaaa
    27481 gatgtagatg gaatctatat tcctactgat aacacgttcg caagtgcggc aagtgttgtc
    27541 ggtgaagtcg caaaagaaac aaaaacacct gtcgttgctg gcgcagttga tcaagtcaaa
    27601 gacggcggtc tagcaacagt aggaatcgac tacgaaagct tgggcaaaca aacagggatc
    27661 atggcagcaa aaatcttaga cggcaagaag ccaagtgaac ttcctgtcga aacagcgaat
    27721 gatttggaac tgtatgtcaa taaagacatg gccaaagcat taggcatcaa tccagacagc
    27781 atcaaagaag ctgaataaaa cacaggagga ttctcatgac aaatttgctc tctcttttct
    27841 tatcatctgc atcgcaaggg gtcttatggg ccctacttgc gattggtgta tacgtcactt
    27901 tccgtatctt ggacattgcc gacttgactg ctgaaggaag cttcccttta ggtgcaggga
    27961 tcgcggcagt aagtattaca aatggctatc atccattgac agcttgtctt ctaggctttt
    28021 tagggggtgc ggcagcaggg cttgtttccg gactgcttca cacaaaattg aaaattcctg
    28081 cccttcttgc agggatcatc accatgactg gtttatattc tgtcacgtcc cgtgtgatgg
    28141 gtgctgcgcc gaacatctct ttattgggtc agccaacgat ctttcattgg gtcgagtcat
    28201 tcggcataac aaaagacaac gctgtactga tcgtcggtct gctttttgct ttgatcgttg
    28261 tatgtttact tgttttgttc ttacgtacag aaacaggact tgctattcgt gcaactggcg
    28321 ataatctggc aatgagcgaa gcaaacggga tcaacacaga taatatgaag atcatcggtt
    28381 atatgatttc taatggatgc attgctcttt ctggctcctt gcttgcgcaa aacaacggct
    28441 ttgctgattt gaattctggt attggaacga tcgtaattgg acttgcttct attatcatcg
    28501 cagaagtttt gttacgtaac cagccactat ttctccgtct cttgactgtc gttttaggtg
    28561 cggtcattta ccgttttatt ttagcgttag tcttcgaact gaatgttgaa ccaagtgatt
    28621 cgaaacttgc ttctgctttc gtgctagtga tctgtctttc tttcccgcag atccagcaaa
    28681 aattccattt acctcaaaaa aagaaaggcg gtagtgtcaa atgaatgacg tcttaacatt
    28741 ggaaaatctc catcatgcct ttgaaaaagg aacgatcaac gaaaatcatg tcctgaaagg
    28801 cattaatctt tccttagatc ccggcgactt cgtgacgatc atcggtggaa atggggctgg
    28861 taaatctact ttgctgaaca gcatcgccgg tacattttct gtcgatcagg gacaaatttt
    28921 attgaatgga aaaaatatca cgaaaaaatc tgttgtcgaa cgttcgaaat ccatcagtcg
    28981 cgtattccaa gatcctaaac tagggacagc cgttcgttta acggtagaag aaaatcttgc
    29041 tcttgctatg aaacgaggaa aaaaacgcgg cttcttccgt ggtgtcaaac cacaagaccg
    29101 aacatttttc aaagaccagc tggctcggct aaatttgggg ttggaaaatc gtttatcctc
    29161 agaaatcggt ttgctgtctg gaggacaacg tcaagctatt acgttgttga tggccacatt
    29221 acagcgtcca gaactgatct tattagatga acacactgca gcgcttgacc ctgctacttc
    29281 caaaacggtg atggaattga cagaaaagct gatcactgag cagaatctca ctgcttttat
    29341 ggtcactcat gacatggaag acgcgatccg ctatgggaat cgactgatca tgctgcatca
    29401 aggaaggatc gtcgtagata tccagcaaga ggaaaaacag cagctcacag tgccccaatt
    29461 attagcgttg ttcaaacaaa acagcggcac ggcattaaaa gacgatcaag tacttttatc
    29521 ttcataatca gaaagaggct gggacaaaaa atgaacgccc accctcttct tttttctctt
    29581 tccttctttc gtttttgctt tatgtatcaa ccgttgtttc ttcgaaaact attttgttct
    29641 ctccttcttc ctgatagaat ggatgggaaa ggagcttgat gccatgacaa cgaaagacaa
    29701 ggtacttcaa ttattgaaaa agacaccaga ttttctttcc ggagaaaagt tggcacagca
    29761 actggaagtt tcccggacaa gtatttggaa agccatcaaa gaattggaaa aggcaggcta
    29821 tcgttttgag cacgggccta cagggtatcg ttacctgccc tctgacgtac tagatgcaaa
    29881 agaaatccag caagagctac ggtcgtttat tcctgatttg aaagtacaaa cgatgttgac
    29941 ttctgaatct acgatgaaag atgccaaact ggcagcagct caaggagatt ctgtttcgaa
    30001 gttatttgtt gctgatacac aagaacaagc tcgtggacgt tttggacggc cttttttcgc
    30061 tgaacctgga cgaggaatct acatgagtct cttgctccat ccagacaaac ggtttgatga
    30121 attgcctcaa tatacgatca tcgcagccag tgcctgtgtg aaagccattg aatctgtaac
    30181 cggtcgttct gcttcgatca aatgggtcaa tgatatctac atggatggaa aaaaagtctg
    30241 tgggatttta tctgaagcag tcagtgatat ggaaagcggc aggatcagtc atatcatcat
    30301 tgggatcggg cttaattttt ctgttcctca aaatcatttt ccagctgatc tccaagaaaa
    30361 agccacctct gtctttcccg acggacaagc tagtgtcaca aggaatcagc taatcagcaa
    30421 aatctggcaa gaattgttca cttatctttc tcacccagaa aaagcgttgg acttctataa
    30481 agaaaaatca ttcgtattgg gaaaaaccgt gtcgttcaat caaaaaggaa cgacttatgt
    30541 cggtcttgca aaagaaatcg gtgatcatgg cgaactgatc gtccaaacaa atgaacagga
    30601 gatgagtttg tcttctggcg aaatcagtct cacatctatc cgtacgcaat aattatcaga
    30661 tttcacaaaa ggacacctga tctcatacag tgtccttttt tctgaattct cttcaaaaga
    30721 ctctccttat tctatcagct gacagtttct ctatcctcta gaaaaaggta ttctaaaaat
    30781 atctataaag catggtacac tttctttaaa tgaatcaatg caaaaaacaa gagagtcatc
    30841 agtttacacg atcaaaagag atagcaggcc gcttcctttt tcaatcttat agatagacca
    30901 tgggtaacga taaaaacaaa aaagaacttg cgacttattt tgccgtaagt tcttttttag
    30961 ctagtgcctt aatctcttaa tcccaacaaa cgtctcgcat agatcacctg accagagtgc
    31021 atagcagcat catcaataat agaaacgaga cgcattcctc gtgtgactgg tggtgtccag
    31081 ttctcgtcaa ttacttcatc tagctcggaa ggttccagcc ttcttaagta agaaatagca
    31141 aaatcagcag ctcttcgcaa gtatcctagc agatcttcta tttgattagc ttggatctgc
    31201 tttgcttgtt ccagactatg cttccaatct tgttcgttat ctgctatcgt catcggaaac
    31261 cggctttccc agtcttgact atgccaaatt ggagaagttc ctgctaaatc agcaatctgg
    31321 aaatctaatt ctcgagcggt atgccaagcc agccaagtca ttgatttgat ctgcggggct
    31381 ctatcttcca ctggaaaacg attggcctcc tcaatagaga cgccttcaaa caaacgttca
    31441 aaccgatcgt atgcccgatc cacactctcg catagcatat ctaaataatc catttatttt
    31501 cctccttttt atttatccta cttacttttt cctaattcta ggatacctac ttatatgtta
    31561 ctacacaccc ttatttttta cactttaaca gtcaccatca tcaatagttt ggagattgaa
    31621 agaaaaagat agtgtcgaac tatcaattga acaagaagca acaatatgaa cgtttcatta
    31681 atattcttta aataaacaat gatttttcaa acgaacagtt taagactagg agaaaaagag
    31741 tataatagga aaatgtttga aaggaaagga aggggaaaaa tgaaaaaaag ggcaagttta
    31801 ctagtcctag ttgctttgtt gttcaatatc ttttcgtatg gtgtggccgt ttcagcggaa
    31861 acatacattc ctaaagaccc tgggaatatt tataatgatc taaccggtaa ctatggcttg
    31921 ttaggaattg ctagtcaatt ccacgtattt gctaaaaata agacaactgt gaatgcacat
    31981 acagacggaa atatagcaac acatgaactt gatgcaaaaa ataattttgg tacagagctt
    32041 catgaaggtt tattgaacca agaaataaat tatatacaaa aaactgattc tttcgctaat
    32101 tcttcaggca tacctacagg tagcacaaga atgaataaat ttgtcgttga cagtaacgtg
    32161 gatgtagcac ttcaagatgg tcatcctaca gtcaatggat ccaggcttga tcacttaact
    32221 ccagatgatt tttataaaga tcgtgctggg catgaatata ttgatttcga gcaggaattt
    32281 gctaaattga atgtagcagc aaatgatctt gcaaccatca ctccagctaa aacatatact
    32341 gctgcagatt ttccagacat gaacaatcgg acaatcgatt taactggttt atcagatacc
    32401 gggtttttat tggtaaatat cgatgcagaa gtgttaacga tgaatacgcc acttcaaatc
    32461 atcaatccaa atgatcaagt agttgtattt aatgtcatca acagttcttc tgcattgaac
    32521 gtacagtcac caatcaaata caatgatcgt tcaaatcatg aaacagaaga tttttcggat
    32581 gcgaatatct cttggaattt tggaaatgag atgactgatt tgacaatcag tgctcctttt
    32641 caaggaacaa tccttgcgcc taatgctact atccgcatta ctcaaaacca agacggaacg
    32701 attataggga caaatgtgat tttagatgca gctaccaatc gttgggatcc taacgaaata
    32761 tttatcagcg acaatggtac agatacgaca gacacaagcg acagtacaga tacatctacc
    32821 acaagtgata gctcagattc atcagcttca agcgatagta cagatactac ctctaccaca
    32881 a
//
LOCUS       DADVXB010000014        32415 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.014, whole genome shotgun sequence.
ACCESSION   DADVXB010000014 DADVXB010000000
VERSION     DADVXB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.014"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(28..1392)
                     /locus_tag="KB902_000501"
     CDS             complement(28..1392)
                     /locus_tag="KB902_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6807354.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(1389..2948)
                     /locus_tag="KB902_000502"
     CDS             complement(1389..2948)
                     /locus_tag="KB902_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807355.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(3004..5484)
                     /locus_tag="KB902_000503"
     CDS             complement(3004..5484)
                     /locus_tag="KB902_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807356.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            complement(5468..5803)
                     /locus_tag="KB902_000504"
     CDS             complement(5468..5803)
                     /locus_tag="KB902_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807357.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(5817..6851)
                     /locus_tag="KB902_000505"
     CDS             complement(5817..6851)
                     /locus_tag="KB902_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6807358.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(6941..7621)
                     /locus_tag="KB902_000506"
     CDS             complement(6941..7621)
                     /locus_tag="KB902_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6807359.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(7791..8750)
                     /locus_tag="KB902_000507"
     CDS             complement(7791..8750)
                     /locus_tag="KB902_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6807360.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(8971..10074)
                     /locus_tag="KB902_000508"
     CDS             complement(8971..10074)
                     /locus_tag="KB902_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6807361.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(10296..10766)
                     /locus_tag="KB902_000509"
     CDS             complement(10296..10766)
                     /locus_tag="KB902_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBB6807362.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            11023..12342
                     /locus_tag="KB902_000510"
     CDS             11023..12342
                     /locus_tag="KB902_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBB6807363.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(12545..13399)
                     /locus_tag="KB902_000511"
                     /pseudo
     CDS             complement(12545..13399)
                     /locus_tag="KB902_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
     gene            complement(13412..13687)
                     /locus_tag="KB902_000512"
     CDS             complement(13412..13687)
                     /locus_tag="KB902_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807364.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(14049..14504)
                     /locus_tag="KB902_000513"
     CDS             complement(14049..14504)
                     /locus_tag="KB902_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807365.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(14658..15866)
                     /locus_tag="KB902_000514"
     CDS             complement(14658..15866)
                     /locus_tag="KB902_000514"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6807366.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(15978..16310)
                     /locus_tag="KB902_000515"
     CDS             complement(15978..16310)
                     /locus_tag="KB902_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6807367.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            16458..17333
                     /locus_tag="KB902_000516"
     CDS             16458..17333
                     /locus_tag="KB902_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6807368.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(17415..17996)
                     /locus_tag="KB902_000517"
     CDS             complement(17415..17996)
                     /locus_tag="KB902_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6807369.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(18002..19261)
                     /locus_tag="KB902_000518"
     CDS             complement(18002..19261)
                     /locus_tag="KB902_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6807370.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(19263..20309)
                     /locus_tag="KB902_000519"
     CDS             complement(19263..20309)
                     /locus_tag="KB902_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807371.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(20544..20819)
                     /locus_tag="KB902_000520"
     CDS             complement(20544..20819)
                     /locus_tag="KB902_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6807372.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(21062..22372)
                     /gene="der"
                     /locus_tag="KB902_000521"
     CDS             complement(21062..22372)
                     /gene="der"
                     /locus_tag="KB902_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6807373.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(22554..23783)
                     /gene="rpsA"
                     /locus_tag="KB902_000522"
     CDS             complement(22554..23783)
                     /gene="rpsA"
                     /locus_tag="KB902_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6807374.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(23918..24598)
                     /locus_tag="KB902_000523"
     CDS             complement(23918..24598)
                     /locus_tag="KB902_000523"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6807375.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(24647..25282)
                     /locus_tag="KB902_000524"
     CDS             complement(24647..25282)
                     /locus_tag="KB902_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6807376.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(25348..26751)
                     /locus_tag="KB902_000525"
     CDS             complement(25348..26751)
                     /locus_tag="KB902_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6807377.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(26738..27769)
                     /locus_tag="KB902_000526"
     CDS             complement(26738..27769)
                     /locus_tag="KB902_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807378.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            27800..28021
                     /locus_tag="KB902_000527"
     CDS             27800..28021
                     /locus_tag="KB902_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6807379.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(28186..28923)
                     /locus_tag="KB902_000528"
     CDS             complement(28186..28923)
                     /locus_tag="KB902_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6807380.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(29076..30416)
                     /locus_tag="KB902_000529"
     CDS             complement(29076..30416)
                     /locus_tag="KB902_000529"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6807381.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(30653..32176)
                     /locus_tag="KB902_000530"
     CDS             complement(30653..32176)
                     /locus_tag="KB902_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6807382.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
BASE COUNT         9256 a         6798 c         5590 g        10771 t
ORIGIN      
        1 ccacacaata aaagaccgtg atatttctca cagtctttta tctactctat tgctatttgc
       61 tctcttagct agtactttaa aagctaactc attgaggtag tgaaaacgag aggtgtattc
      121 agacagaaat ccaaaatcct caactgctag ctgtggaatc gtagttttgt gtttcacgat
      181 atccgcaagc aggttcaaat ctgataataa gaattcttgg cttatcagct gtccgccaat
      241 tatttctaat gtatccggat ggtagatcag ctttgcattt actgttttgt tttcttcgtc
      301 gtattgtgga aatagatcaa attctcctga acacgaaccg gtattttgtt ccaagaatgg
      361 cgcttcatct tctgtcagcc ctacagttcc taaaaagtag tctataatga ctgctgctgt
      421 tatcttttgt ctgaggtcgt aagcggttgg ctgaccactc aaagttagcg ctactgctct
      481 tgccatatgt acagctcgag taactaaagg taaaaagaga tgccgtttat ttttgtcaaa
      541 actgactggg acgatatctc caatcgcata gatgtccgga tcacttgtct gcagatattc
      601 attgactatc acagtctcat cctcatacaa agccactttt tcttttaaca atgtcgtatt
      661 aggacgagtt tgggcagaaa aaatgaccat atctgccttt attgtttgag acagaagttg
      721 tacggatact actttctctt ctgatttttt ccaatcgatc aagaattcat ttggataaaa
      781 atttatttgc ttagtttgca gctgattttg aaaactgttg atcatatcct tatcgaaata
      841 tcttgataaa acattcggca tataatcaac tagatgaata atgtatcctt tatttctcaa
      901 agcatctgct aattccaatc caatgtaacc agcaccgaag atcactactt cttttgcttc
      961 ttttaaagcg gcaagtactt gcttagattg cactagattt ttataggtgt agacattttc
     1021 agcttcaatt tgtttataca aggtgacagg agaggaacct gtcgctacga ttaatttatc
     1081 ataggttatg gtctcgtttt ttccttcttt ggatgcgagg atgagctgat gtttgtctgg
     1141 atcaagttca gttactctcc attcggtgat cagttttgcc ccactttctt gaagagtccg
     1201 catgttatgg gcaacttcag ctaaactacg tatctttcct tttaaataaa ggttgattcc
     1261 atttgaaaca tagcctagtc catctttatg atcttcatcg atcagtaaaa cttctgcttt
     1321 cggttgaagt tttcttagat ttagggcagc tgtgatgcct tcatgggaag caccaatgat
     1381 cacgattttc atgttttatt catccttaaa ttcaattttt ctaaataaca ttcttttaaa
     1441 aattggttca aataggggaa atcataatta tattcgttgc tagtgaatac aaaaacttta
     1501 gcggacttct gtgacgggta ctctttcaat tggctagtca aaatgatatc atactgcttt
     1561 tctttctcgt attcgactaa atcatatttg atcgtattca gcaattgttc ctggatgatt
     1621 tctttcacga tatccgccat tagcctttca taaggaagat cataagcaat ttgcagacgt
     1681 aattctaact gcttgatcag cgtccgtaaa atagatgcat agcgagcaaa taattcaaag
     1741 cgggcatttt cctcgtctac ttcagtaaaa tcaacaatag caaatgtttg tctgaccaat
     1801 ctttcacata aaaccaggaa ttgtttatct tctacttcag ttaaccgctg ttttaatcct
     1861 tcttggccaa aaatattcat ccatcctcta aaataggcaa aatgagcgtg attttgcatc
     1921 actgtcaacg caatcttttg cgaaatctct tctggaaaaa cataaaaaga gaaatattct
     1981 tctatcgatt gtttaaacgt tcgattcaat tgagctacta cgtcgtcttt gtatttttcg
     2041 cttatcaaaa actcctggac atgcgagtta tgtgtatcta atgtaaagtt actgatcatg
     2101 aaaagataaa aaaccaacgt ttcattttga ttccaaggaa aggcatattg aaagaagtaa
     2161 cgggtcaaaa atgtatggag gtccaataaa aattgtgtcg tttgaaacaa tccaacagga
     2221 agattgctat aatctggttt ggattttttc gtacagcgca ttcgcttctt cataatggaa
     2281 agccatattt caaatttcaa tcgtccttct tctgtaatag caaaactaaa ctctttttgc
     2341 agcagatcta aaaaagtgtt tcctgataaa tcactgtatt cttttttgtt ttcaagatag
     2401 ggacgtccaa accaaaataa ttggaaataa aaataacgaa tttgactttc tggaccggtc
     2461 agccgcccgc tttttatttt cagatgaaac tcatttaaag aatcatttaa ttccttcact
     2521 ctgcgagaca aagtagccga actgatatta agttccatga caagtttctg ccgatcaaat
     2581 gagccatttt ccaacagata aagaagtatc tgatattttg tagaatagcg caagtaacaa
     2641 tgataataaa catcgactgc tgctatattt ccatgtctga ttaataaaat attcccttct
     2701 tggataacaa tttccaattg tttgatattt tccaagttag cttgtaaata aaacagatct
     2761 tctttcaagg tagcccgatc aactgataag cgggtaagta cgttattaac ggaaacctct
     2821 cctttttcct ctaataaaag ttggaaaagt ttgatttgcc gttgttcatt tttttcaagc
     2881 aaactgaaaa gttccaagtc cactccttca agcatttctg attttaacag cagaagtttc
     2941 cttctcatcc ttgaaaaaga ggatctgtga cagttatcac agatccatac aaattctaat
     3001 cacttagctg gttggcccag ctgtcagttc ccatgtgacc atgccttgat acgttgcgcc
     3061 aggttgagca ttcgtactgc tatttacctc taagagtaaa ccatcggtat cgggaaagtc
     3121 aacgagaacc tctcctttag ctgttccatc actctcataa atcaacgtgt tttgaccttg
     3181 ctgaatcaat tgctttgatc cagaatgatt gaagtataat tttgttccgc ttaattcttg
     3241 accttgatca ttcttaaata aagaagtcaa tgtacctgtc agttgccaag gagacgtgct
     3301 tggaagccga gtatcccgca catcaaaaga aaaatcgcct tttgattcat aataacttgt
     3361 cttcaacggt ttggggagat cgttaccaaa tgtaaaatca tctggtacat taactaatgt
     3421 taattcttgt ttggggacaa gaattgtttt agcagatgtt tggacaactg ggttaggaag
     3481 cttagcacca tctgctaatg taatattgct ggaaagtaca gctgcctttg tcagtatgct
     3541 gacggattgt aaagaagtat ctacagtatt taattgatag ttgtaagtaa gatgaatggt
     3601 atctcctatt ttgctcaata gatctgctgg gacagaaact ccttgttgaa tgccggtatc
     3661 tgcgatagtt gtaccattta attttaagga accattgata taagtagtat tttcaggaag
     3721 tgagatcgtg atttttttgt cggttatcgc atccccagat tttgttaacg tgaatgtcac
     3781 attttcttga atcgtatctc ctgatagagc agacagggga tctcctgtct caggttgtct
     3841 gctaaggttt tttagctgac tatctgcact cacagatgga aaattagcca ctgttatttg
     3901 aggaagagtg gtgattccag cttgttcaga ctgccatttg tacgcaaaag acggatacat
     3961 gttagtaagt acatcgtcca ccaagcgata atcaaaataa tattgccctg aagccaatgc
     4021 aggtagtgta gaagtagctg tatttacacc cccgttattt gattggatcg tttggaaaag
     4081 ttgatctgtc catcctgtcg ctaatttttg ggttcctttc gaataaagcc tgtaatggat
     4141 cgaacccttt tttagttcag ttgctgacca attggccgtg acttggtacg atgcagaaga
     4201 aaggagcttt ccccactgac tatcggctgt taagtttgtt ggtaaaaccg ttccgtctag
     4261 cttgtactgc tccaatacct ttaaagcaac aggagaaagc aatccgcctt gcgcatcttt
     4321 cccactgtac acgatattgg ctgtctgatt caatccactt gtgcttgctg gagtatgagt
     4381 cagtattgct ccttgtgtaa cgttttttcc tgtaaaatag ttgactacgc gatcaaagcg
     4441 actaaatggc aactgatcaa aacgtccttc agtcagcccc atcgtcaatg tccgactatt
     4501 ggtagagcct ggaaggttct ggttatttcc atccacgtat tctgtggtat cagcaaatgt
     4561 attatatttt cctgttgaat cacttggtga gatgtaacta ttccacgtat ttatctctgc
     4621 acttgcagaa aatgcatatg ctcctggatt caagtttccg ccagttaatt taggataaaa
     4681 tctacctgca gctggagcta aaatcgaatt gaacatacga tcttggataa tattattcga
     4741 atcataaaaa tcaacagaaa aaacggcctt tttagacata gaaggttgta atttaccctt
     4801 ggtcaaaatt ttgtttggac tcgtatcata tttatctccg ttttctgtca tcttcgcgac
     4861 attagctgta acatcaaatt gaagcgggat atcgtccacg ttgaattcgc ctcgcgtaat
     4921 aatagcaata atatctgtca atagagtatt tgtatcccac gaccccatcc caaaacgcaa
     4981 ggtatggctt cctgctgata ataaacttcc gctagtaacc ttgatggggg caccggcaat
     5041 atacaagtag gcgttgttcc agtcaattgc ttttaataca tcactgcttg atacatgttc
     5101 cggcaaattg atgatcgcca caaatgcaaa tccttgtgca gtgatattca ccaaatcaag
     5161 tacatttgtt agtttcacat ggctttccca atgaaaacgg accgtgccac ctttccaagg
     5221 atcatttgaa ccatcgttca aataagtagc agtcaattta ggcaattggt tagccccagt
     5281 tagttggaca agcttcccgc cattgactgc actacgtcca ccatttggag gtacgatatt
     5341 ttcatacgtg tatggatcat aagaaatggc aggaggcgtt gctccaacag cttctgccga
     5401 aggtgaaaag ataaatatac ttaaaacaaa aagcgaagta aaaaagaagg agcgaaaaaa
     5461 tgaaaattta ttttgtagca acatgttcat cctccttttc ctttcttctc cataacaaca
     5521 accacgcaag aagccataat tctataccaa tgatcaaata aagaaaacgg atcttttgtt
     5581 cattcgtctc cgggaatacg ccatgttgat tagattcttt ataaatcggt agctgtgtct
     5641 gctgttttga tgcgccattg actgaaccac ttggatgcgg aattggactt agatcataaa
     5701 atgtaatcgt acctgaactt ttggtatctg cttggactgg ctcttgccag ctgaagaaca
     5761 gcaaacttgc aataatccct cccaataaga tcgatgtttt caacgaaatc acctcatcat
     5821 gttgtttctc cttttttctt tttcttgtgg acccacaaaa acagcaaaat caaccataac
     5881 actagaactg cagcaaccaa tcctgcataa agccatggga aagattgttc ttgtactgca
     5941 aaaacggaat tttcatttac tttttgtgct ttttcttttt tgatcgtaaa gttttgtgta
     6001 aatcgccatt cattactgtc gcctgatttt gctatgattt ctgcgcggta atcgccggct
     6061 tttgctttat caccagctaa atcaagattc aagtgaaaat tcgaatttgg tgcaactaaa
     6121 aatgcattag acgtattttc aatataaagc tgattttcat aaaagatctt gctcgtaaat
     6181 atcaaattgc tgataatcct aggctgagga ttttggaaac gaagctgaac agttggcttt
     6241 gcgttgacct cgtccaaatc tcctgataaa agtttcagat ccggttctat cgtctcttga
     6301 ctttcttgta aaacgactgc gagattataa gcaatacgat ttttgatttg tgctccttct
     6361 gtagcatttt ctgtttcagc ttcttcttta ggtgaaacat gaatacccgc taatacacgt
     6421 cccttaaagc tttttgctgg gattttcact tctataggta cagttgtttc tgcatgtgct
     6481 gatacattga tttccttttt cgcaatgagc aaaacgtcac ggacatcaaa cggcaatgtc
     6541 tcatctaacg ttgggttttt ttgactataa tcgatcgttc caccatcact cgttaccgcc
     6601 ggattgacag agacctcaaa tgttcgttct tcatctgaag aattgctgat aattacttct
     6661 agtgtctgat tttgttccgg tgccactaat aaatcaaaat aaccgattgc tttatctatt
     6721 tggttctctg gaaataccgg tttgattcca aagtctcctg ctgaatcctt tgcttggctg
     6781 attgacggaa aaatgaaaaa tagacttaaa atagaaaaaa acgaaacaaa cagtcgttta
     6841 ctttgattca ttgtccacca catcctttca acaacaactg cggtaaaaaa tccttcacct
     6901 atagtatttt caccgcagtt tgttgaattt atttcatact ctatgctact gggccagcca
     6961 cgaggttcca agtcaaatca gccgtgaatg ttccagctgc tgctttcggc actttcagtg
     7021 tgatatttgc tggatcataa acagaaagcc atgttcccag accttgatct tttgctgctg
     7081 taaatattgg tgtcgctgca cttgctttac tcaacccagt tacagtttga ctagttggtc
     7141 cagtggattc gttatctgac gtacttttaa cagtggatgt tccaaaatct aattcagcgc
     7201 cttgcaaaac ttgtgaaccg tttacaaaat ctgaaaccga aactgtcacg ttccaccctt
     7261 gtgcttggcc atctgcacct acacctcgac gatctgatac ttggagataa ggtgtatcgt
     7321 tttttgaagc gtctacttga tacgtttttg ttccgctttc aatctcgtgt gtaccaaatg
     7381 gcaattcggg aactacatcc agtgttaaag gacctgtctg gccagttgct ggattttccg
     7441 gatctgctgg ctctactggt tttgaaggat cagtagggtt aagaggctcc acggtatttg
     7501 ttggttcagt aaaggtaata tctccttttg aagtcgcttg accctcagca aaagctggtg
     7561 ttgccaagcc gcctagaaga agtgttgaaa gtaataatgt cccaatcatg ttctttttca
     7621 taataaatca ctcctttttc ttagtgacct aagtatagta gagacagtat gcaaaaaatc
     7681 ctcatgaatt catccgctta cttgaaatta tgaccctttt tgtataaaag agaaaaaaac
     7741 aataaaatcg tttacatgaa tattcttcct tttttattaa gtttcgtttg tcaaattaag
     7801 ttagacaaat catcttttgt gacgtaactc aaaaatactt ccattggtgt ccgatagtgt
     7861 aatgattttc taggaatatg atttcgtttc gatgccaccg attggataaa ggtttcagat
     7921 acaccattaa aatccatagc tttatacaaa ccatctttac gtaataagcc atttgaatgt
     7981 tcattcaatc ctcgttgaga aggtgttcct ggatccgcaa aataaattga aatatcgttg
     8041 gtattactaa tctttttcca atttgagaat tcttttccac aatcaaatgt gatggattta
     8101 aataagtttt ttgggacaca acgaaaccat tgattcagcc tattttcaat gtctttagcc
     8161 tgtctgcctt cgggtttcaa ggtaatgatg actttagata gccgttcaac taatgtgatg
     8221 accgcgcttt tatgttttcc acccacgata gtgtcacctt ccaggtgacc aaattcatga
     8281 tcaaactggg tatagtctgt ctttctgtct cggattgacc ggcgaaaccc ttgttttcct
     8341 cttttttctt tatgaccgtt tggttttctt tttcccttca ttggtaaatc gtgagtgtca
     8401 aaggttttat ctttaaacat tcgatacagt gtgcgtaccg aacaagcaat aggaaactct
     8461 gctcgaccaa taaggacatc aggagcccac ccttgaacaa cctttttttg aatgtattcc
     8521 tgttgctcat caggtaaaac aatcggatgt cttccgcagt tacgtttgtt tttcttatat
     8581 tgtttatagt agctcattgc gcttccacca gatttaagaa aacgatagac cttataaata
     8641 gtttgtcgag aacgttgtaa cagattggct acttttgaaa caggttgtga ttgattgaaa
     8701 taagcttcta tcattacgag ttcagttggt gtaagatggt tataggtcat ttgtactcac
     8761 tccttataat tctttcgtcg gaactatttt gagtgtagca caaatgactt tttttagttg
     8821 tctagcttaa ttttacaatc ggcgaagtat gaaaaaatat ttcaatttta ttttttcgtt
     8881 tcaaattatt ctattagtga catccttgaa ctataaaaat aggagtacgg catcatctgc
     8941 cgcactccta tttttttcgt catttgtttc ttaaataaaa cgattctcac gcaattttat
     9001 ttttttgata tcttctactg tttgtgttcc agctaattgc atgaccattt ccaattctgt
     9061 tttaaagaaa tcaaacactt gatggactcc tgtacttcct cctaaagaca atccataaat
     9121 aacgggtctg ccaatagcaa caagatctgc acctgatgcg attgctttga aaacatgctg
     9181 tccgcgtcgt acaccgctgt caaacacgat tggtacacgt ttatctactg cttctgccac
     9241 atattgcaac gaatcaaacg ctgctggacc accatctagt tgacggccac catgattaga
     9301 tacccagatt ccgccagcac cagattctaa tgaacgatag acatcttctt ctgactggac
     9361 acctttcaca tagactggca aatcagaatg agcagcaata aattctacat cttttggact
     9421 aagcttctgt ttggaagatt tgtacacagc atccatcgtt tggcctactc ctgattgata
     9481 agcctgaacg atcggcattg gcagtgggaa ggtaaaccca tttctgcggt ctgtttcacg
     9541 gtttccgcca actgttgcat ccgctgtcaa tacgattgct tttgctccat tacgcttggc
     9601 cacttcaaga atatccaaat tgatcccatc atctttgctc atataaaatt gaaaccattg
     9661 cggtgctttc tccccgcctg cttctcttat ctcttctaat gtacaagaag cgtaagaact
     9721 tgctgtatag atcgtcccaa aatctgctac accttttgca gaagctttct ccgccttcac
     9781 atgagctaag ccatgagcag caactggtgc catgatgatt ggtgcagtca gcgtttcttt
     9841 gtcaaaatgt gtagttgtat cgggtaattc tacatctctt aatacatgag gaataatcag
     9901 ctgatgattg aatgcccgtt cattttcttg ataagtaaat aagtcgccag caccactgct
     9961 gatgtaacca taaccaccag ctggaatcac ttgtgaagcg gctatttcta aatcttccat
    10021 attgataaaa tccactattc cttcatttgt acctgcttga tacgtttttt ccatttcaat
    10081 gccttccctc tataaaaaat tgaatgaata atatgatagc gtttacacac tttatattac
    10141 tcttccgtat tgatacaggc aaataatctg tttacatttc agtcattcca gttgttacta
    10201 ctctgaaaga aatgtttaga acacaaatag ataaaaaacg atgggatttt gacaaaagtc
    10261 gtgtcaaagt cccttttacg aaatactgtg gatgcctatt gaaataagtg cgggttgttt
    10321 ctttgtattt caatcgtttc ttgccattct tcgtttaatt ttggattacc gttttcttcc
    10381 ttgaacgcat aaggtcccaa tccaaaaagc tcagttagta tttgattcac gattccatat
    10441 agctcggtgt gatcggacac atgattattg aagatcatct cattatcacc acgtttgaat
    10501 ctcacattcg ggctctcatg atgaacctct atgcagtttt cccctttttt taactgacgg
    10561 atttctgaaa acatctcata aatatcttct ccaataaaac cttcagcaag cgccagactg
    10621 tccacaagac cgcctactgt caactcagag attatcgctt tgttggcacc aagctttaat
    10681 gtatagcttg ttgcttctac tacgccgcat gcattgcaac caccttctga tagttcgctt
    10741 tttctgatca attgaacttc tttcattttc tgttcctcct cttagttttc tacttatgta
    10801 ttttttatca cctgacgtaa gtgtatttta tcgtcacgat cacgtgattt attcttcaga
    10861 gattctacct gaataattca tacttttaat taaaaccatg tgaaactgcc tcacggcagc
    10921 ttacaattac tttttcatct tcacccgtta agtgatgaaa aaagaacccc tttctgctat
    10981 ggttaaagtg actaaaccaa ccaaaagaaa ggagttcttt tcatgactag cttacacaaa
    11041 aaccaagtaa aattcaattc aaatatcact atttctcata caggtggtca attatcgagt
    11101 gattcgggtc tcgtcctagt gaaagagctg atgaacatct ttggtttttc tgaactggct
    11161 aagcaacaca ttcacattga agacgaacga gcgtatttta ctcatgacaa cttatccata
    11221 cttgagcagt tcattatgca attaattgct ggttactcag ctgattctgc agctaatctc
    11281 ctgagacaag atcctgtgtt taaagctgtt ttagatagga aagaactcgc ttctcaatct
    11341 tcactttccc gatttttaga tcgactatct gaggagaata tccatgaact tcaagctttg
    11401 aaccaagaac ttatcgataa agcacgcctc atccgtaatg atacggaatt aatcattgat
    11461 ttagattcga cccattcaga tacatttggt caccaagaac aaacgaatta taatacacac
    11521 taccaaacct atggttacca tccattggta gcttttgacg gattgactgg tgacttctta
    11581 aaagctgaac tacgttcagg aaatcaatat acatcaaaag gcgtaaagga gtttctcaca
    11641 cctttattag agcactataa tcactctcta ccaaacactg acatcttggt tcgtggagac
    11701 agcgggttcg ctacacctgg tgtgtatgat tcgtgtgaat caaaaaagag tcattatgtt
    11761 attcgactga agaataatcg tagactaggt caaatagctg agaaatcagt actttatggc
    11821 gataatcaaa agtgggaaga acgagaagtt cagtacttct cgaccactta tcaagcacaa
    11881 tcctggtcac aaagtcgtcg cgtgtgtata cgctcaacac gtgaagcggg cgaactactc
    11941 tttcgacatg aatttatcgt gacgaatcta tcagaaaatg tttctcctga taccatcttt
    12001 tctatctatg ccaaacgtgg cacaatggag aacttcatta aagaagcgaa agctggcttt
    12061 tactttgaca aaacagacag tcctcgcttt ttggagaatc atgtccgaat gatgctcagc
    12121 ttgatagctt acaacttagt caacttctta agaacgattg gctttgaaga agtccaaaag
    12181 ggaatgacca ttcattctat tcgattgaag tttctgaaag ttgctgggaa attagtccaa
    12241 acgggtagac gagtctatct caaattatct agttatcatg tgtatcagaa tgaattctac
    12301 agggtctttg ctcgcctgag gcgagccagt caatggatct aatccaacaa tctaacgatt
    12361 tttttactgg gaagttatcc agggagaagt atgctcaaaa tgccttacac ccaaaattta
    12421 ttcctcaata tttttgaaca gtgaatgttt gaagtaactt tttagtcaaa atcagttgat
    12481 agggatatta gtgatacata tttcaataaa atgtgccaaa gaattaaagc tatgaattat
    12541 tcaggactaa tgcattcagt gtaaaagcaa tagttgtcca tgtactgtgg gacaagctcg
    12601 acaattctgc atcaaacaca gagattttcc taaaaccaga agcttggaga atacctgctg
    12661 ccactgcagc aatgattcca gatacatcaa atgcctctgc caatacatag gctagaaaag
    12721 gaagcaaaag ttcgatcagc agataccctg tgacatcttg tgctgatgct ttttcgatca
    12781 aatgaattat tttttgtttg aaccagacaa gcaaaaagcc gatcaaagct cccccaatac
    12841 tagaaactac tagactcatc cccgcgttta ctgctgaaaa agatccggtg atcagcgcac
    12901 caagagcaaa ctggaaggca gtaacaccag atgcatcatt caaaagacct tctccttcca
    12961 aaatatgcat cgccttttta gggatattca ctcgtccaga aagagaactg actgctaccg
    13021 catctgtcgg acctaacgct gctccaaaag caaagcaggc agcaagtggg acacttggca
    13081 acaggaatga taacgtcgca cctaccccga caagggtcaa aatgactcct ccaaatgcca
    13141 agaacaaaat tgtcccgaaa tttttgagaa tcgaagaaat atctgctttt tctccttctc
    13201 taaataacaa tggtgcaata atcataacta agaacaattc aggttcaaaa tcgattgatt
    13261 gtccccactc tgtcagacct aataccactc caaggaaaat ttggatcagt ggagctggaa
    13321 tcattggcaa aatgcggcta gctatgttcg ataaggtgat cgttactgca aatacaataa
    13381 ctaactcagc aaattccatc gtccatcccc tttatttttt attttgtgta agcattttta
    13441 aaaattgttc ttttttcttt aaaattttgg tttcgactac ttcaacctgt gtttggttcc
    13501 cctctaattc acactgtaca cgttttgact ccaaacgaag cagatcatgt ttcagacgtt
    13561 ccaactgacg atacatcaat atatttcttt tacgcaactt acaaagtatt tgacggcggt
    13621 catccatcga aagggcgcca tagcgatcat gcaacagttt tttttgttgt tcaaaactct
    13681 ctctcatttt ccagatctcc tatacacaaa cttccatcat tatagcaaag ttctttttgg
    13741 atgaaaaata tttcattgtt tcatcgttta ttgctagtta gaaatttcca taaatttttc
    13801 aacgcctcat tctattccaa atagtatcag atatcaagta aaacttaaga aagataaaag
    13861 tttctgacaa aaggatgttt actttcccat tcctgccttt cttgttcttt tatcacaaca
    13921 aaaaaatggg gctgcgacaa aaatcttgtc acagtccctt attctgaata aacggtgtgg
    13981 aagagacagc ctatcagtag taataagaca catctctttc acagcctcat ttttgcgtaa
    14041 aaatcgattt attcgaaaaa ttccccgtat acatcttcta cacgttgatc tggattgatc
    14101 acgatataca agttacctgt tttttcgctg atttttgttg attgatattg attgtctaat
    14161 ccttctgttc ctttatctag atatgggaag tacacaagat caggtgtgcc atttcggtaa
    14221 aggatttcca ttcgctcgat atcttcgtat ttcaatgcgc gattaaacat gcccatttcc
    14281 agtccgccta ggttgatatc atgtgtcgca actgcgtccc cttcatggaa gatttcgatt
    14341 ttaaatccag cacacggatg gatttcaaca aattcactgc cattgattcg tccaaaactt
    14401 gttgtgattt gtttgatcca aagatcgccg atatgacggc ggttgatcgt ccaggtttct
    14461 ccatttctaa aataaaattt tagcgctgtc atttctttac tcattaaaaa gactccttta
    14521 tgatgtaatt tattcttgta ctacctcagt ttagcacaaa tttatgtaag tggtcacatc
    14581 ttatgttttt tcttctaatg acgtatctgc ccactttaag tagccaacaa agctgagcag
    14641 atacagtcta gtgtttttta aatcaatttt tctttcgata aaaaatccaa aacctgtttt
    14701 ttatcatttt ttattctttg ttctacgacg gctttttcag ctaattgcaa agcttcacta
    14761 acccacttac caggtttttt tccagtttct tctagcaaga ttttaccatc tactgctaat
    14821 tcgcttaatg acttgatagg taaacgatca taggattctc ctacggcatc catctgaggt
    14881 gtttcgtcaa aatagatcat caattcttct acttgcagtg catgtttttt gcctaagaag
    14941 tacaattcga atggttccaa agctccagtt tctcgttgtc gtagtccttg gacaagtgct
    15001 tgaacgtctt taatcatttg gttagaacac ttccacgatt tcaaaaagga acgaatctca
    15061 ttttctttta gatccagttg gctgatcaat aatgcccatg cttggctctc ttctttcaat
    15121 gggacggatg gtaattcagc aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga
    15181 cagcaaatgt agcactctgt ttcaataaat gcatggattc ccgcggcccg ttcatttccc
    15241 aagagcatct tgatgaattc cacatttata cgttctacag atattttacc taatagctcg
    15301 tggttttctt tgatggcgta gaaggtttct tcctctaatt tgaaccctag ttgactgaca
    15361 aaacgcaacc cgcgcatcat tcgtaaggca tcttcatgga accgctcatg aggattgcct
    15421 acagctcgca agatctgttc ttctagatct tgcagaccat cgaacaaatc gatgatttct
    15481 ccatcttctt tcaaagcaaa cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc
    15541 aacgaacgaa cgaattcgac atgatctggt ctacggtagt cctgataagt tgattccgtc
    15601 cgaaatgtgg tgatctcata ttgttcatca ttttctaata ccaacacagt tccatgttcg
    15661 atcccaatat ctatcgtttt tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt
    15721 gcgatatcca catcatggat tggctggttc agcaagatat cacgaacact tccacctaca
    15781 aaataagctt catatcctgc attctctaat tttttcagaa ctggaattgc cttttggtat
    15841 tccagaggta attgttttaa tttcattttt ccaacctttc ctgcgtgttt cttgtcctga
    15901 gataaagact cagttgcatg gtgactgttt gacaagtccg tttcagagtc ttcaaggcca
    15961 ggaccacttc atcttgttta ctcgtcctta cgctcaaagc gattatggtc tctttgattg
    16021 aatttttcca tgtttttttc aaaaacttca gttaagtcga tattcaatga attagccatg
    16081 atcatcgtaa cgaataaaac atcaccaagt tcttctgcta ccgagttaac tggttcagaa
    16141 gcctttttgc ttttttctcc ataagtgtgg ttgacttctc ttgccaattc acctacttct
    16201 tcagttaatc gagccatctg agctaatgga gagaaatacc ccaccttgaa ttgctggata
    16261 tattcatcca cttcctgctg catactgtat aaagaacgct ttttatccat ctttttccct
    16321 ccaaaactat cttaccaaaa ctttaacgca aatcctagat aagagcaatt gagaaaatcg
    16381 aatttccatg ctacatttag gaaggaattt ctaaatggaa attctgtgaa aatacataat
    16441 tgaaagctgg aattcatatg gtcaaacgaa aaacagtaaa agaagttctt tttatcatta
    16501 taggaacaag tatttatgca tttggtcttg tttacttgaa catcgctaat catttagcag
    16561 aagggggagt ctcagggatc accttgatct taagagcttt atttggtatt gatccagctt
    16621 atacgacttt attaatcaac atcccattga ttttactagg aggaaagatc ctcggtaaac
    16681 gttccttggc ctatactgtt ctaggtacac tttctttgtc attcttttta tggatctggc
    16741 aaagggttcc actagaaatc aatttacagc atgatctact gatcgtttct ctacttgcgg
    16801 gtttagttgc aggtgtagga agcgggatcg tctaccgcat gggtggaaca acaggcggca
    16861 gtgatattat cgctcggatt ttagaacaaa attacggcat cactatgggg cgttccctat
    16921 tggcatttga tatcatcgtc ttacttgctt cattaaccta tatcgacttg aaacgtatga
    16981 tgtatacgtt gattgtttcg tatgttttca gtcgtgtgat tgattcgatc ttagatggcg
    17041 gatattctgc aaaaggtcta cttgtcgtct ccaacaaaag cgaagagatt gcaccactac
    17101 tgatgaccgg tctgcaaaga ggtgtgactt tcctttctgg agaaggcgca ttctctggta
    17161 attcaaaaaa aatcatctat atggtcgtta gctctagtga attaactgaa gctaagagga
    17221 tcgtccacga gattgacgaa aaagctttcc tttcaatcat caatgtgcat gaagtggaag
    17281 ggcaaggctt tacttatttg aagccacaga caagattact gaaaaaacta taagaaaaaa
    17341 gacaaagata ggctatgagg aaagattcca catccagctg acctttgtct tttttagtac
    17401 tatactattt ttaactaatt gttatgttca cttacccggt tacttttctt ttgtgtctgc
    17461 aaaaggatct ttcggttaac ttcatcagat aatttcaaaa aagcatccct atctccatct
    17521 tctagtgctt gatcgatttg agcataaagc atttttagtt ttgcctcttc ttctttttct
    17581 tgaaaatatc gttcaattaa ttcagtatct tcttcactga ctgaagaatc ccaagaagaa
    17641 aatggattgt cttctaagat agatagatat tctcttgtct gccaagcatt ttcgaatata
    17701 cattccacat ataaaggctt tttccaattc aaacggattt catgaaaaat ctggtctgtg
    17761 tccgtaaatt cttttccctg caaaaacaat ttcatgggtt ccccttcaac agatagatca
    17821 ctgatctgca gtcctcgatc cgcaaaattc gccccttcaa caaagtggac attgcttaaa
    17881 atcgcttcat gattggcaag ataattcaag atccaaaaaa cttctcttcg gctaaaagat
    17941 acatgattga ccatccacgt taaaaaattc ttcttttccc gtacatcaat tagcattttt
    18001 ctcacctctc tgttaggtca tctaataatg acagtgcctc catatctcct ggttcaagtg
    18061 ttaaataata agtcaataat tcttgcgctc ttttcagctg cccttcttct cttaagaaaa
    18121 aggcatactc tttcaagaaa tctggttcat gtgatagttc atgataagcc tgttcatagt
    18181 gtacagctgc aacggtaaag tcttctaatt cattataagc atgggctagg ttccattctg
    18241 cataaggatt agcagtttct tccatctgat tgatcacttg tatcacatct tcatatcttt
    18301 catcatccaa gtaaagatta cttaaagtaa gtaatgtttc atcttgtttg tctcctactt
    18361 ctaaagcttt cagtaaaagt tcttctgctc gctgtctatc atgcagacgg aaagcatttt
    18421 ccgaggccag gtgataaagt tcgacttggt aaggattttc tttgattcct tcttctaaca
    18481 ctgtttgtgc ttcttcaatc atttcttctt cttgaagagc ttgtcctaga tatagatata
    18541 acgattgata atgcggatta acttctcgaa gttcttccag atagttgatt gcctgctgat
    18601 tttctttcaa ttgaagattc gtaaaagcta gctggaacag tcgatcatct gtcctttctt
    18661 ctttcagtgc ttcttctaaa ggtacgatag ctgcttcgaa ttctccttgc atacttaagg
    18721 attgtcctaa acgttcctgc atcgagattc ctgaaatttc atttatcccg cttgccaaca
    18781 atgtttcata aaccactgct gcctctttga aacgatcaac tgaaaaatac aattcagcta
    18841 gcgcaaactg gatcaatggt tcatcaggaa gcaacccagc tgcttctttc aattttgctt
    18901 cactcacttc agggattccg ataacttggt acaaatcagc tatcgccaat aagctttgcg
    18961 gatagtaatc actttgctta tccacttttt ccaggtattc aaaagctaag tcgatctcat
    19021 tatcttcgat tgcaatttct gctaacggga tgttcagtcc gtcattttct gggtattggt
    19081 tgatcagttg ttcaaaaatc tgttttgctt cgatcaaaaa gccaatagcc agcaattctt
    19141 cgcctagttc agctaatata tctgctgggt cttcttttaa tgctttttct aaaaagattt
    19201 gtgcttgtga caagtcttca tctgataaag cttgcaacat tttttcgcta tttgtattca
    19261 tttcaattcc ctcttatctc actgacgatt tgttgaaata ccgtcattgt tctcaataat
    19321 tctttttcgt ttggatgttg gtatccgtct attataccta ttttttctaa aacaagtatt
    19381 tttttgcttt tttctgccaa aaaaagaact ttttccaaat actccatctt tgaaatctgt
    19441 tccagccagt ggattggata gccaagcaag tccagccaca caaaaaagtt ttttagttgg
    19501 aaatcaaaag gatatgcttg gagattccac acgaaatgaa acatcattcc taaaaatttt
    19561 ttcatactag cagaaagtag atggccattt tcggtcagat aaaaagcttg ttcaaacagt
    19621 ttaccataat ttgacaggtt ttctgcctct aattgataaa aatagatcat ttcttcgatc
    19681 atcccggcaa acggccgagt cgttaattgc tttttatttg gatagttttt atacagattt
    19741 tgcaaaaaac gatgatcaca aatcattccg caacagataa aagtcaaaaa gtcaatctgc
    19801 tttccgtcca cctgccgctc gctgattgtt tgatcataaa cgatgcgttc tggcagattg
    19861 atggtttgca gcactacacg atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct
    19921 cggcttagag aacggatcga tacagggatc atccatagtg atgaatcaag ggttgtatgt
    19981 ttttgaaaaa aacctgccag atccatgatc ccttcatttc caaatccgat gataaacatg
    20041 gattgatttt cgggatagcg tttgacgaaa tcaagcaggt tctttaattc tgttaaatga
    20101 ttgcattgag tgttggcaca aatataccag tcattgtttg cttgatttgc aaataacggg
    20161 ttgatcttat ctgcaaacaa atcataatag cgctgattcg ttaaaaataa gattggctga
    20221 tcaatggaaa gttctcttag ctgactgact agcgtttctc cgtaaaacac tttcgtcaac
    20281 gcatcttcta cttgataatc aagttccata cgcatccctc ctcttcttat ttttatttta
    20341 ccattagtaa gcaaattcta gaaaagataa gagcaaagct cacctcataa cttgcaaata
    20401 aataaaaatt aaataaaata catgtgtttt ctatgtatga catacggatt cggaatctct
    20461 gtctcttatt tattcctttt ctgctaggaa ataaaaagaa aagcacttgt agccctagag
    20521 ccacaagcgc tttttcaact gtcttattta acagcgtctt ttaatgcttt acctggtttg
    20581 aatgcaggta ctttgctagc tggaatttcg atttcttcac cagtttgtgg gttacgacct
    20641 ttgcgagctg cgcgttcgcg aacttcaaag ttaccaaaac cgattaattg aactttttcg
    20701 ccgttagcta aagcatcttg aatagttgaa aatacagcat ctactgctgc agttgcatct
    20761 tttttagtta aatcagtagc tgaagcaact ttttcgatta attctgcttt gtttgccatg
    20821 gatagattca cctcctccac aagagatatg atagaaatat catttagtta aaactttctg
    20881 agtggtccag aagtttaaaa agaaatattg attaacttca atattctgtt atcacgatat
    20941 catatgaacc gcttaatagc aaggttttta ccaattttca catgcttttt ttagtcatag
    21001 aaacgtaaca aacgaaactg tctttttctt ttgaaaaaaa aacgtcgata tggtaaaatg
    21061 cctattttct cctacgaggg ataattcgga tggacgtccc ttcaaaagta aatgcttttc
    21121 tgatttgatt ttctaagaaa cgttcataag aaaaatgcat caattcctct tcattgacaa
    21181 aaacgacaaa tgtaggtggt ttgacagcga cttgtgtagc ataaaaaatc ttcaggcgtt
    21241 ttcctttatc tgttggtgtt ggattgattg ctacagcatc cataatgata tcattcaaca
    21301 cagccgaaga gatacgaaga ttctggttca tacttacttg ttcgatcatt tcaggcagac
    21361 gttccaaccg ttgtttagtc actgcagaaa caaaaacgat tggagcgtaa tcaagatacc
    21421 ggaattcatc acgaatctct tgttcgaaat cacgcattgt attggtttct ttctttacaa
    21481 gatcccattt attcacgacg ataataattc cacgaccagc ttcatgggcg taacccgcta
    21541 ctcgcttgtc ttgttcccga atcccttctt cagcattcag taccatcaaa acgatatcag
    21601 aacggtcaat ggcacgcatt gcacgcatca cgctgtattt ttcagtattt tcgtatactt
    21661 ttccgcgttt acgcatacca gctgtatcta tcattaagaa tttctgacca ctttcagaaa
    21721 cgaagtgggt gtcgattgcg tctcgggtcg ttccttcaat atccgaaaca attacacgtt
    21781 cttctcctaa aatcgcattg atcaaagagg atttaccaac atttgggcga ccaatcaaac
    21841 taaacttaat cgtgtcgtcg tcctcttctt cagtctcttc agagaaatac ttcactgctt
    21901 catctaaaat atcaccaatc cctagtccat ggcttcctga aacaggataa ggatcgccta
    21961 gccctaagga ataaaattca tagatatcgt ttctcatttc tggattatct actttattga
    22021 ctgctaaaat cactggttta ttacttctgt ataaaatttt cgcaaccatc tcatctgcgt
    22081 ctgtcacgcc ttcgcgtccg ctgactacac aaatgattac atctgcttct tcaatcgcga
    22141 tttctgcttg atgcttgatc tgatccataa aaggttcatc gccaagatca attccgcctg
    22201 tgtcgatcac gctgaattct cgacctaacc attcaccttt tgcataaata cgatcacgag
    22261 ttactccagg agtatcttcg acaatcgaga tacgctcacc agcgatgcgg ttaaaaatcg
    22321 tagacttacc gacgttcggg cggccaacga ttgcaattgt tggatttgcc atattatttc
    22381 ctcctcacaa gtttccaatc tcacttagtt taacgaatgc attgccaact ttcaagcata
    22441 gattgtcaat taaacgaagt atttttattc cttattgaaa tactaatcgc ttttcaaaag
    22501 aaaaactgag acaaaagcag ctgctttcat ctcagtcaca gatacaaaat caattatttt
    22561 tcagaatcat cggttgcttt ttcttctact tcttctttca acgcatcacc taaaatgtct
    22621 cccatagtaa atccagtatt ttcttctggt aattcataag actcaacatt ttttggttct
    22681 tcttctgaag ctggtttttc ttctaaagct ttgatactca atgcaatacg atgttcttct
    22741 ggatggatct ctaatacttt cactttcact tcgtcacctt catgaagcac ttcatgtggt
    22801 gtcgcaatat gtttatgtga aatttgagag atatggacta gcccttctac tccagggaac
    22861 acttcaacaa aggcaccgaa gcttgtcaaa cgtttaactg ttccgtctaa tactgtgcca
    22921 actggagctt ttgtatcgat ttctgaccaa ggtccaggct gtgtgtcttt gattgacaag
    22981 gaaacacgtt cttgttcagg attgatagac aacactttga catttacatc atcattgaca
    23041 gccaatacat cacttggttt tgctacatga ctatgtgaaa tctctgagac atggactaga
    23101 ccgtcaattc cgcctaggtc gacaaatgcg ccaaaatcag taagacgtgc aacacgtcca
    23161 ctgagaacat ctccctcatg gatagttgaa agaatttctt ttttcttttc ttctctttcg
    23221 ttttccacta ccgctttatg cgataagatc aaacgatttt ctgatggttc gatttcgatg
    23281 attttaaagc tcaatgtttt gcctttatag tctgaaaagt ctgcaacaaa atgatcttcc
    23341 accattgatg cagggacaaa accacgtaca ccgacgtcaa cgactaaacc gcctttgaca
    23401 acatttgtaa caggtgcttc gatgaccttg ccctcttgga aatctctttc gatatcttcc
    23461 caaacttttt tagcatctaa acggcgtttt gaaagtagat agctgccgtt ttctttatct
    23521 ttgccgatcg tactgataac gactaaatct aatacatcac cgacttttac tacttcgctg
    23581 atatcttcta ccggcaaagt tgataattct tttgccggaa cgactccttc aactccagcc
    23641 ccttcgattc cgacaatcac ttgtttgtct tcaatgacta aaacttcgcc cttaacaaca
    23701 tcgccaactt ttacttcttg tacgcttttc attgcgtctt ccattgactg gttgttctct
    23761 tgattttgat caaattctgt cataacactt gtcctcctaa ccaacattct gccgtaagta
    23821 cggtactgtt tttagtttaa ttgattattc aaaaaaaata aagcgatttc gttcgttttc
    23881 cttgaaaaaa caattgtttt tcattttttt tcttaattta aaaaagaaga taaccttttt
    23941 tcaaaacaac agcttttatt gctgcaacga cttctggaat cgatttgcca gtcgtatcga
    24001 tacgaacagc atcctctgct tgcttcagcg gagagacgtc ccttgttgaa tcataatggt
    24061 ctctttcctg tatctctttc gtcagtgttt caagatcagt cggaattcct ttttcttggt
    24121 tctctttgaa acgtctttct gcacgctcac ttacgcttgc tactaaaaag attttcactt
    24181 ctgcattcgg taatacagct gtcccgatgt ctcttccgtc catgacaacg ccaccgcgtt
    24241 cccctatttt tcgttggaca gcaactaatt cttctctgac ttttccatgt gcagagactt
    24301 cagaaacagc ttttgtgaca tctggttgac ggatttctaa agtcacatct tttgatgcta
    24361 tgaatacatg ctgtccatct tcttgttgcg aaaaagagat aggatacttt ttgatcagcg
    24421 aaactagccc ttcttcatct gaaaaagata cattgttcgt aatagctaaa taagttactg
    24481 cgcgatacat ggcaccggta tctgtataaa tataattcaa ttcttttgct aatatcttgg
    24541 caacggtact tttcccagat gaagcaggcc cgtcgattgc aatactgatt tgtgtcatga
    24601 tataactcct ttttctcaga aaaaaagccg caaagcgcgg ctattattat ttaattctta
    24661 attcttgacc agggtaaagc ataaagttgt ttggatctaa gccattcaat tcaaacaatt
    24721 gatcagtggt gatccctgca cgctcagcca cttgttttgg accttcgcct gcttgaacag
    24781 tcgttgttga accggctgca gctgatgaag aaggtgttgt ttctgctgca ttgctgcttg
    24841 aatcccctgc ttgataagtt gcctcacttg aggaagtcgg tgttgtctct gctgcaatac
    24901 tgctttctga cgttacacct gtatcttgag acacagtaga ttcttccgcg attgtactag
    24961 attctactgt tgaagtctca gttgactcct cttttgttgt acttgtagaa ctttctacta
    25021 ctgatgtcga agtttcagaa gaagttgctg ctgttgcatt gttgcttgat ccatttctga
    25081 tccagaaata agcacctgct ggaatagcga tacataagac cagtaaaatc aaaaatagcg
    25141 aaagaaataa tgtatttcct ttcttttgtt gtctctgaga acttcttgat gaaacttcat
    25201 catctgtatc gtagattggt tgttcccatg gttcttgtgt ttcgttattt tctgtagatt
    25261 gatgtctatc ttttctgctc actgttttac ctcctaaact ctatcgtgtg tattatacca
    25321 taggaaaaag tgtcttgtcc taaaaaatca atgttccatg ttttttttaa ataaatttag
    25381 taaaatcgtt tcccaatgaa gttgttcagt cttagaaaaa agcttcctct ttggcagaag
    25441 ttctgctttt gctccatcaa tatcacaaca attctgcggc ttttcggaga gtttttcgcc
    25501 aaaataagct aagatgaatt ttctgcggca gttttcttca ttaatatagc gaagcatctg
    25561 ctgcaggcgg aattcttttt ctttttcctg acgtttgagc cgttccaccc aattttctgg
    25621 tttttcagac tgctggatca gctccatcca ttttttttgc agctcatcaa agggagcttg
    25681 ctctgtggca tattccaaat aaagctcaaa actttgtcgc tgttctctag aaagttgatt
    25741 aaagaaataa tggatacgtt catccccact ttgataaaaa agaattgctg cactttcttc
    25801 ctgatctctg cctgctcgac cgatttcttg tacatagttt tctagactgt ctggcaaatc
    25861 ataatggacc acataacgga tatcagattt atcgatcccc ataccaaatg cattcgtagc
    25921 aatgagaaac tgcagctgat tttttacaaa ctgctgttga agttgtcttc tttgagctgc
    25981 atcaagacca ccgtgatagt atccaactgt aaaacgttcc ctgaataaat gatacaatcg
    26041 ttcgacttct ttttttgttg cacaataaat gattgccgct ccttgtgctc tttccatgaa
    26101 gtgttcaagt tcttgttctt tttgctgcgt tttccgaaca aaaagcgaga tattttgccg
    26161 attgactgat tgtctgatct cttttggtgg tcgatcaaat agtacatgac gtatatctct
    26221 tgctactaaa tctgttgctg tcgccgttag tgccagtgtg accgggtttc ctaaaagctt
    26281 tcggattttt cctaactgtt gatattctgg acggaaatca actccccatt gagacacgca
    26341 atgagcctca tctactacat ataacgcaat attttgtttt ttcagatgct ctaaaagaga
    26401 aggattagtc aacatttcgg gactcaaaaa caaaaattta tattgcgata gatgacggag
    26461 gacgtatctt ctttcagatt gcgaaagtaa actattgaaa gcagctactc gtttctcccc
    26521 tcgtttttgt aattgcgtca cttgatcttc cattagagaa agcagcggtg acacgatgat
    26581 gaccagacct tccattaaat accccgtcaa ttgatagcaa aggctttttc ccgttcctgt
    26641 aggcaaaata gcgagagtat cttctccatc aagcaacgcc tgaataattt cttcttggcc
    26701 gggacgaaat gaatcaaatc caaaatattt ttttaattca tttattaaca ttctgtatcg
    26761 cttcctttct caatagatag atttgataca aacgaaattc tccataatct aattgtccat
    26821 ctacattcca ttcgctaaag cgccactctc gcacggaatc cttatttggt tccaaacgtt
    26881 cgattgtttc tgcagagaga atccactcgt atggaaaatc atcaaaaaac aaggcccact
    26941 caataagatg atctgttact gttcctcttt ttaaatgacg gattgccatg atctggtcaa
    27001 ttgtctgacc attcataaac atctgcttgg tgatcatcat gctttgattg aaattttgct
    27061 gtaataatga atcgatcaaa gcgtgccaaa gcgaatctgg ccgtttttcg atttgtgcta
    27121 acaaaaggtg gatacatctg ctttgttgca gataaaccgc tgactcatca ttgttttttg
    27181 ccagctgata aggaagcagc cctgttcgct catttccaga taattggtta gctaaaaaat
    27241 ctgctgcttc ttctggtatc tccgaaaaca gctgcaccaa actctcatac gcagtatcaa
    27301 tcaaaatttc acgtggcaat tggctttcac taagccattt ttttagttgg aaagtataaa
    27361 aaggacttgt ctctgctgga agatagtctt gaatacccgt tgccagatta gaaattactt
    27421 gaacagcaaa tttaatgagc cgccaactag tttcccctgt tctgccatag cggtcaaaac
    27481 gcaaaccagt atgttctatt tgatgttcgg acaacatatc agcccctgca ggcgttagct
    27541 ttgcttcatt ttcatttatt tcgatccaac cttgctgcgc aattttttgc aaaatttgat
    27601 aaaacttatc ctgcttcaat tctggaaaac tgttatggat aaacaaaagt tcgtgggtaa
    27661 atccataaat aagtactgaa gtcgttcgtt ttcccacaag gagttggtaa agagaactaa
    27721 tccgcagctt gtgtcctgat gaaaatagcg ataaaataaa aacaatcata ttattctcct
    27781 taagttagga tggttagaaa tgtcactact atgtaaactt gtacctgaac gctgtattgc
    27841 atgcggtctt tgtcaaatcg aagcgccaga tattttcgat tatgatgaag aaggaatcgt
    27901 tttatttgcc caagaaccag aggctcatca acagttcgtg atgccggaag aagaaacata
    27961 tgtaaaaaaa gcgtatcaaa aatgtccagt tcgagcgatt ttattagaaa ataaaatata
    28021 aatataaacg aaactttaaa aacgtacact aagttctcta aacttgaaaa taagccggga
    28081 tctgtttctc ttgttccgtg aaatcccgac ttattttgaa agattcattt gctatctata
    28141 gttaattgac tagttttttc acggacccta taggacccat ttatattatt tcaacttttt
    28201 cagccagttt tccaatgtat tgacgatcac agtttgctgg tctgcgttag aaatttctgc
    28261 ctctccatct cctttttgct caccatagct gccaaaacct ccatgatttc cgccattgat
    28321 tgatacatac tctgttcttt ccggtaaata ctgcttagct tcttgataag cttcctgatt
    28381 caatacttta tcttttgtcg ccgtgatcga taaaacagga acagctgatt ctgtcaatgt
    28441 tccttttttg tcgggataac ttgccatgaa gaatacccct tttaaatgtt tgtctgaatg
    28501 attcttattg acataacgac ttgccattac gccacctaat gaatggccac cgatcacata
    28561 atcggaattt ggaaaatctt ctttgacctt atccgctttg tttccgccca tcactgctag
    28621 atcaagtggc attttgacaa tagcgactga aaagccgttt tttgctaaat cttgcgccca
    28681 aatactataa ctttctggct ctacgagagc accaggataa aaaataagta atggagactt
    28741 tccatgattc tttttctctc cttcaaaaaa taagtaatct tctttgtttt ttccttcttt
    28801 taccaacact tgcgcttctg acgatggttc gtacgtattt tgctgtatat agtaataacc
    28861 ggctccaccg agtaatccta aaatgatgac taagccaatt agtattcgtc taaatatttt
    28921 cactttctcc caccttttct atctgagtga cccctttttc ttaatcaagt atgattatac
    28981 cttaaaaaaa taagagagaa atgcaaactt tccagcatca aataaaaaaa gacggaatat
    29041 ccatttgaat atccgccctt tttgtatgtt tatttttatt tagcacataa acgatacaca
    29101 gcttctgcat aaatttccat tgctttatac atactactta attcccatcg ttcattcgcc
    29161 tggtgcataa agtcaggagt atcagggaac atcgcaccga atgccacaca ctggttcatc
    29221 gtacgagcaa aagtagcgcc gcctgataca aacggttcag tcatgtctcc agtaatatcg
    29281 cgatatgtcc ccaatagatt tttcactaac tcactgtcta gtggcacgta taatgaatca
    29341 aggaagtcaa attcttcata agtcaaccca tatttttctg ctgttttagt taatttagct
    29401 actaaatcat ctttcttgaa tgtaacaggg attctcatat ctacaccgat ttttgtttgt
    29461 tctggtgtga tttccaaact tgcaaagttc atcgttagct cgccggattg ttcatcttct
    29521 gttttgccca cgacagcttc accagttgca ttttcttgaa ctaattttcc taagaaattg
    29581 attgggccaa aatcaaatac ttctgaaaga gcaattgcca gacgagaaat agcattcact
    29641 ccttgtgctg catctttcgc gtggatactt ttaccaagaa cgacgatgcc ttcaccttgt
    29701 tcttcgaaat cgaattcgtg ttttttcaat gcttctttta cttcagaaag cttttctcca
    29761 gagtaaggag ctgcatcagg aacaacattc aacgctcctc cagcttttac agaaaactcg
    29821 ttcgttcctg gtcctgtcaa gtaagcttgc aataagcctt tttctgcata aattaaagga
    29881 aattcagcat ctggcgcaaa tccttgcgta attccttctt ctttttcgtt atatttttct
    29941 aaacaacgcc ataaattttc ttcatctgta ccaaagataa aacgaatacg tgtcttgaat
    30001 tccacgccag catcaatcaa agctttgacg gcatacattg ccgcaataga aggacctttg
    30061 tcatcttggg atccgcgacc aactaaccag ccgtctttta tagttggatc gaatggtttt
    30121 gtttcccaat tattttcgtc ccctgctgga acaacgtcca tatgacacaa gataccgaat
    30181 aattcatctc cagagccaat ctctgaataa ccgtaatagc cttctggatc tttaaatgtt
    30241 ctaaatccta gcttttcact gatttccaat actttatcca aagcttcaat cactttttta
    30301 ccgaagggat gtccttgtcc tgaatctgct tcatctagta cggaaggaat tcggatcaat
    30361 tcgctcaatg attctaatgc ttgttcatga tgttgttctg tcacaaattt tttcatgata
    30421 ttatcctcct aatatgttaa aaagggtcat gtcaaattcc tccgacacaa cctcttcttc
    30481 tcaaataatg acgttttaag cctgctccat cagcaagcag aatgttctta acaaatgatg
    30541 aaagaaaaaa cactcactga atggagctat tgacttatcc acgtgcttat cgatagccgt
    30601 ttatcggttt cttcattctt atgatagacc ttgtacctgt atttgtctag gtttagaaca
    30661 ttgctgctac acctaggatc acacagatgg ctacaaataa tatcgcaatt aatttaccgg
    30721 taaatttcca ccacactgaa acatcgaaac gagcaattgc tacagcaccc attacgatag
    30781 cagatgttgg tgtaattaag tttactaaac cagatgcaga ttgataagca gtgattacta
    30841 aatccttacc gacgccggca aattcaccca taggtcccat gattcccatt gttgcagcag
    30901 ctaagccgga agttgaagga atcaagaatg acatagggat atagaaaata aatgtaataa
    30961 tgatgaatac acttgaagat aatgaactta atccttgttc gccccaatgt aagatggtgt
    31021 ctgtgattaa tccattgttc ataaccactt ggataccacg agcaacagct actacgattg
    31081 ctacaccgat caaatcagaa gcaccagcta aaaattcaga gacaaattca gactctttca
    31141 tgccataagt gattgctact acgatggaca ttactaagaa taacatagta atttctggga
    31201 agtaccagtc acctaatgga agcatgcttt tacctagaac cgtacctagt accggaaggt
    31261 ttgttaacca gtttgtcaat gattcaaaaa tcgtgaaatt cgcattcaag gttgtccaag
    31321 gaatcaaact gatgatcatg ataccaaaag taataaagaa caatacatta acatgttttt
    31381 gttttttcgt gattacttct tgacgaccga ttgcttcaat atcgaaatgc ttcatatctt
    31441 ctttacgttg gttgtatact aatgattttg ttggatcttt ttcgatcttt gatgcataac
    31501 gatacacata tacaatagaa atagctaaca aaataacgaa catcaagaat cgaagaccaa
    31561 taccttcacc catcgaaatc ccaacagctt gtgaagctac gcctgttgca aaaggattta
    31621 ccgttgaagc tagacagcct acttgagacc ctactaatac gattgctaca gctactactg
    31681 tatcaaagcc tacagccatc atgactggga tcagtaaagc atagaatgga atcgtttctt
    31741 ctgccattcc gtaagtagag ccgcctaatg caaataacag catcaatact ggaataagca
    31801 ttttttcttt tcctttgaat ttcttcacaa ctgaagcaat cccggcatct agtgcccctg
    31861 ttttgttgat aatacctaaa aatccaccaa caaccaaaat gaagaaagag attgggattg
    31921 cagcaggtgt ttctttagtt agctcccccg ctggtacacc tagcatccca ttgattggcg
    31981 ccatgaaaat atcccacagc ccttgaggat tttgttgtac tcgttcatat gatccagcga
    32041 cgatgttgcc tgcatcgtct acactatagt gcccagctgg tataaaccaa gtaagtacag
    32101 cgattactgc aataataata aataagaccg tatacgctga aggcatttga aattttttct
    32161 tttttgtttg ttccatcttc ttcttccttt cttttccgtt agagacaaca attttggctc
    32221 taatgttatt ttatcaaaaa gagtatcaga acaaaaataa taacacgcat tttgtaaaac
    32281 ttttgttcaa aaagttcgtt tttccctatt ccctcctctt ttttcaggtt tttaaagctt
    32341 tcttcttttt cattgtagcg tttccttttt tttataaaca aacattttcg tcttttaaaa
    32401 ggagaagaat ttcac
//
LOCUS       DADVXB010000015        31697 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.015, whole genome shotgun sequence.
ACCESSION   DADVXB010000015 DADVXB010000000
VERSION     DADVXB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.015"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..169)
                     /locus_tag="KB902_000531"
     CDS             complement(<1..169)
                     /locus_tag="KB902_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HBB6807383.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQ"
     gene            complement(258..1481)
                     /locus_tag="KB902_000532"
     CDS             complement(258..1481)
                     /locus_tag="KB902_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6807384.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(1498..2544)
                     /locus_tag="KB902_000533"
     CDS             complement(1498..2544)
                     /locus_tag="KB902_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6807385.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(2708..4435)
                     /gene="ptsP"
                     /locus_tag="KB902_000534"
     CDS             complement(2708..4435)
                     /gene="ptsP"
                     /locus_tag="KB902_000534"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBB6807386.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(4435..4701)
                     /locus_tag="KB902_000535"
     CDS             complement(4435..4701)
                     /locus_tag="KB902_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBB6807387.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            5180..7414
                     /locus_tag="KB902_000536"
     CDS             5180..7414
                     /locus_tag="KB902_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6807388.1"
                     /translation="MLCQNCGKNEATIHLYATINGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            7562..7882
                     /locus_tag="KB902_000537"
     CDS             7562..7882
                     /locus_tag="KB902_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6807389.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(8087..8311)
                     /locus_tag="KB902_000538"
     CDS             complement(8087..8311)
                     /locus_tag="KB902_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBB6807390.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(8509..10089)
                     /locus_tag="KB902_000539"
     CDS             complement(8509..10089)
                     /locus_tag="KB902_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBB6807391.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(10490..11866)
                     /locus_tag="KB902_000540"
     CDS             complement(10490..11866)
                     /locus_tag="KB902_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6807392.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(11994..13112)
                     /locus_tag="KB902_000541"
     CDS             complement(11994..13112)
                     /locus_tag="KB902_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6807393.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            13254..13688
                     /locus_tag="KB902_000542"
     CDS             13254..13688
                     /locus_tag="KB902_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6807394.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(13766..14299)
                     /locus_tag="KB902_000543"
     CDS             complement(13766..14299)
                     /locus_tag="KB902_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBB6807395.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(14393..15571)
                     /gene="mutY"
                     /locus_tag="KB902_000544"
     CDS             complement(14393..15571)
                     /gene="mutY"
                     /locus_tag="KB902_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBB6807396.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(15564..16361)
                     /gene="recX"
                     /locus_tag="KB902_000545"
     CDS             complement(15564..16361)
                     /gene="recX"
                     /locus_tag="KB902_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBB6807397.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            16468..17850
                     /gene="rlmD"
                     /locus_tag="KB902_000546"
     CDS             16468..17850
                     /gene="rlmD"
                     /locus_tag="KB902_000546"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6807398.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(18024..18602)
                     /locus_tag="KB902_000547"
     CDS             complement(18024..18602)
                     /locus_tag="KB902_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBB6807399.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            18924..19394
                     /locus_tag="KB902_000548"
     CDS             18924..19394
                     /locus_tag="KB902_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBB6807400.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(19502..20728)
                     /locus_tag="KB902_000549"
     CDS             complement(19502..20728)
                     /locus_tag="KB902_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6807401.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(21482..21682)
                     /locus_tag="KB902_000550"
     CDS             complement(21482..21682)
                     /locus_tag="KB902_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6807402.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(21816..22424)
                     /locus_tag="KB902_000551"
     CDS             complement(21816..22424)
                     /locus_tag="KB902_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBB6807403.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(22509..22979)
                     /locus_tag="KB902_000552"
     CDS             complement(22509..22979)
                     /locus_tag="KB902_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBB6807404.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINIMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(23027..23941)
                     /locus_tag="KB902_000553"
     CDS             complement(23027..23941)
                     /locus_tag="KB902_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6807405.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            24087..24890
                     /locus_tag="KB902_000554"
     CDS             24087..24890
                     /locus_tag="KB902_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBB6807406.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            25068..26015
                     /locus_tag="KB902_000555"
     CDS             25068..26015
                     /locus_tag="KB902_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBB6807407.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(26083..26376)
                     /locus_tag="KB902_000556"
     CDS             complement(26083..26376)
                     /locus_tag="KB902_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBB6807408.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(26404..27069)
                     /locus_tag="KB902_000557"
     CDS             complement(26404..27069)
                     /locus_tag="KB902_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBB6807409.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(27209..27841)
                     /locus_tag="KB902_000558"
     CDS             complement(27209..27841)
                     /locus_tag="KB902_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6807410.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(27848..28915)
                     /locus_tag="KB902_000559"
     CDS             complement(27848..28915)
                     /locus_tag="KB902_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6807411.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(28912..29643)
                     /locus_tag="KB902_000560"
     CDS             complement(28912..29643)
                     /locus_tag="KB902_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBB6807412.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(29812..30291)
                     /gene="greA"
                     /locus_tag="KB902_000561"
     CDS             complement(29812..30291)
                     /gene="greA"
                     /locus_tag="KB902_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBB6807413.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(30427..31602)
                     /gene="mltG"
                     /locus_tag="KB902_000562"
     CDS             complement(30427..31602)
                     /gene="mltG"
                     /locus_tag="KB902_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBB6807414.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT         9433 a         6445 c         5257 g        10562 t
ORIGIN      
        1 tttgttctgc taccgctttt ggtgtatctg cccagatagc tccttctgtt actaaaggat
       61 cagcttttgc ttttgtccga ttatagacag ctacttcgtg tcctgcttct agtagatggc
      121 gtgcgacagc acttcccatg acgcctgttc cgataaaacc aagtttcatt ttttcgacct
      181 cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc tagaaacaag gattttttca
      241 taaaaaatgt ttgaatttta tcttttaaat gaatttaatt ttattttgat tcgttcaatc
      301 gagtcttctt cttcttttct tcgcatctct tcttcatgat aaacaaccat gtcttgataa
      361 aattcgatca tagcttcgcc gaaatgtgta gatgaaatat cataaagttt agcttctaaa
      421 acttttggat ctttaggaac ttcactggaa atataatcaa taagtgctgg tgcaaagtct
      481 tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga acaatcggtt caaataagca
      541 tttccttcca cgacacaagg tgttccggct gccatcgctt ctgtataagt aagcccttgt
      601 gtttctgaag tagaagcact gacaaaataa tctgccgctt tataataaag tgctacatca
      661 ttgttgtcca cttctcctgt gaactgcaca aattcttcta actgcagttc tgagatcaat
      721 tcctctaact cttctacata aggtcctttt cctacgataa ctaatctggc gttaggataa
      781 gcggagatga cctgaggaaa cccattaatc aaggcttgga tatttttctc ataagaaatc
      841 ctgcttaaag aaagaatcat caaatggttt tcctgaagac ctagtgactc ccttaatttg
      901 ctgatatcct gctgagtgat atcagaacgt ttgaattttt caatgtcgat accagtagga
      961 atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg tatcaataac acgttcactt
     1021 ggacaaacta cacctgtcgt atgatttgca aataatctag acaagtattt tacatgggat
     1081 tgcctgatca cttttccttt accgatataa tgaaggtagt cttcatacat cgtatggtaa
     1141 gtatggatca gaggtatttt caacttctta gctaccatct tcccaagtat ccctgctccg
     1201 aattctgtat gggtatgaat aagatctagt tctagttctt tggcaaccaa ataagcatac
     1261 cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa taaatggtac acttggcatt
     1321 cgaatcacat ctttttccaa cttatccgca ttaggatcgg tcgttgtaaa aatatagact
     1381 tcatgcccat gtctttctaa ttcttgtttt aatgttttga tcgatgtagc aactccgctg
     1441 acttgcggaa agtaggtatc ggtaaaaaag ccgattttca tgtttttcgc ctccaaacta
     1501 gtccttgacc tgatttactt tttttaattt gctagagact ttttcattca gtacactttc
     1561 gtatacattt ttaagttctt caccgatttt attgatactt cgctcttttg ctgtttgata
     1621 accggcttgt gtcgtactcg gtagttcttg attggtaatc tgttggatca gtcggataaa
     1681 ttcttcgttt gtcttcccca tatagcagtt cttgctatct tctaaccagc cattatacac
     1741 tggaatatct cgaacaagta cgttttgttt gcttgctaaa gcttctaaaa caacgatccc
     1801 ttctgtctct tcataagaag ggaaaaagaa tagatctgca cctgaatacg caccttctat
     1861 gatctctcca cgaatgtaac caggaaacag gacattttca ggatgatctt cttttacaat
     1921 tttccggatg ttccgaggaa tcgagtacat gggaacatga ccaaaccaaa taaatgtgta
     1981 ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt cctttacgtt cgaaaaacaa
     2041 accgacacaa atgattactt tttgatccgg agacagtttg aaatattctc tgaacttttg
     2101 ttctttcatt ggatcagggt gatatttctc taagtcgatc ccattggaaa tagcttgaat
     2161 cggcacacgg ataccatagc tttccaacaa ctgttttgaa taaggtgttg gcgtgatcag
     2221 atagtccgct ttttggtaca atcctaccag atattttttt acgataggag aaagctggtt
     2281 cgatccgata aaggaatttc ggaaatcttc ctctgtagaa tgcgcatgat agacaacttt
     2341 ttttccttct cttctggctt tattgaccat attatgacta ttgattccgt atgtattgat
     2401 gtgcaggatg tcataatctt ctttttcatc tagtgtataa gagataccga cttccgtcag
     2461 agcacgtttt tgatgatcaa gcgcacgccc gattccagat tttgcaagca tcttttcact
     2521 ttcaaaatat aataatacct tcaccttacg tcccccttca cttatatagt ataacatagc
     2581 ctacaaactg tcactcaaac ttaagcccta tttttgtcta ttcttactga caaaaacgtt
     2641 ttcttaaaaa agaacaaaaa aactggcgta gctcttttac aagccacacc agcttttgat
     2701 acgttgttta ttttacatat tcatgaacaa gttcaacgac ttcttccatc atatcgcatt
     2761 ctttcaatgc acgatcagca agttcagcca ttttcgctgt gtccaagcgt ttcattaaac
     2821 tacgcgtttt aagaatagat gtcgcactca ttgagaactc atctagaccc atacctacta
     2881 gcaatggaac agctgtttga tctccagcca tttctccaca catacctgcc cattttcctt
     2941 cagcgtgtgc tgcatcaatt acatttttga tcaaacgtaa aattgatggg ttatatggtt
     3001 ggtacaagta agaaacgcgt tcgttcatac ggtctgctgc cattgtgtat tgaatcaaat
     3061 cgttcgtacc tacagagaag aaatctactt cttttgcaaa cttgtctgct aagactgctg
     3121 ctgctggaat ctcgatcatg atgccgactt ggatcgtatc agatacttcc ttgccttcac
     3181 ttatcaattt ttgtttttct tcttcaaaga tcgcttttgc tgcgcggaat tctttgagtg
     3241 tagctaccat agggaacatg atacgtaaat taccatgaac agatgcacga agcaatgcac
     3301 gcatttgtgt acggaacatt tcgtcgcctt gttcagataa actgatacgc aatgcacgat
     3361 atcctaagaa tggattcatt tcatgaggta attgcagata tggtagttct ttatctccac
     3421 cgatgtccat tgtacgaaca actacaggtt ttccttccat accttctaat acagctttgt
     3481 aagcttcata ttggtcatct tctgttggga agtctggaga atccatatac aggaattcag
     3541 tacggtacag accaactgct tctccaccat tattatggac accaactaga tcttttggtg
     3601 ttccgatgtt tgcagctaat tcaaaatgct tgccgtcagc tgtgacagtt tctgcatttt
     3661 ttaatttttc ccattctgct ttttgtgctg cgtaatctgc acctgctttt tcaaattcag
     3721 ctttttgttc atctgtagga tcgatgatta catcgccttc gatcccgttg acagccaaaa
     3781 tatcgccttc tttgacttta gcagtaattt cttttgtccc aacgattgct ggaatttcta
     3841 aagaacgtgc catgatagca gaatgtgaag tacgtccacc aatgtctgtt acaaacgctt
     3901 ttacaaaatt gcgatctaat tgtgctgtat cacttggagt caagtcatgt gcaacaacga
     3961 ccacttcttc gttgatcatt gatggatttg gtaaagtaac gcctaataag tgcgctaaaa
     4021 tacgtttagc aacgtcacga atatctgcag cacgctcttg catataagca ttatcttcca
     4081 ttgcttcgaa cataccgata tacatatccg ttacttcttt tagcgctgat tcagcattta
     4141 cgctgttgtc tttaatattt tgcttgattt gacctaccat ttctggatct gaaagaacca
     4201 tcaaatgggc atcaaatact tgcgcttctg cttcacctaa gctttgcgct gctttttcac
     4261 gaatttgctg caattcttca gtagatttag ctaatgcagc atccaaacga gcttcttcag
     4321 ccgcagtatc ttctactgtt gccttactga atgttaaatc cggttgaact agcaggtaag
     4381 cttttgcaac ggctacaccg tcactagcgg caatcccttt tagcatttca accattattc
     4441 agataagcct tctttcttca ttgtttcaac gattgctgcc attgcatcag cttcgtcagc
     4501 accttctgca gtaatagtaa catcagaacc ttgacctaca cctaaagaca taacgcccat
     4561 gattgatttc aagtttactg atttaccttt atactctaag tttacatcag agttaaattt
     4621 gcttgctgtt tgtactaata gtgtagctgg acgagcgtgg atcccagttt ctgctactac
     4681 gtgaaattct ttcttttcca tattaatcgg tctcctttaa gtgagtgttg tttttatgtg
     4741 agggttttct tttttagtaa ttcagagaat cctaacaaat gccacccttt catctgtaaa
     4801 gattaacatt ttttttcgtt agatacaaca gttttcattc aatttcagat aaaagtattc
     4861 aaattattcc ggattctttt tcatcctttt cttcacattt tataacaaac gtgtttattt
     4921 cctttttctt gtcgctttct cttctcctga cgtttatcat tctttccttt gaccctcttt
     4981 gttttcatat gaaacgaatt acttgcttcc ctttttattt ttagtataat aagagtcaaa
     5041 ggtcaggaat ggtcaataga gatttcacct tttctacctc ataaatctct taaaaaacta
     5101 ggggttattc ttttacctca tgaaaaacga gatgtaaaat atggatgtac ccatttttgt
     5161 gaaaggacgt gaatgattca tgctttgtca aaactgcggc aagaatgagg caacgattca
     5221 cttgtatgcc actatcaatg gtcagcggac acaactcgat tactgtcaga gctgttatca
     5281 aaaaatcaaa aatcaacaaa atggaggtct gactaatatg gcccaaaatg atccatttgg
     5341 atttggcagt ttggacgatc ttttccgttc catgtctcgc caaatgcaac agcaaggaaa
     5401 ttatgagcaa acaccaccaa cacaatttgg cggaaacaac aacttcaatg gtggtcagcc
     5461 acctcaaggc aatacagaag gtttattggg agaatacgga atcaatatca cagaacaagc
     5521 acgacaaggt gatatcgatc ctgtgatcgg acgcgatgac gaaatcaaac gagtcattga
     5581 aattttaaat cgccgaacca agaacaatcc tgtcttgatt ggagaaccag gtgttggtaa
     5641 aacagcagtt gttgaaggtt tagcacaaaa aatcgtagat ggtgatgtac cgcaaaaatt
     5701 aatggacaaa gaagtcattc gtttagatgt cgtatcttta gtccaaggta ctggtatacg
     5761 aggacaattt gaagaacgta tgcaaaaatt gattgaagag atccgtcaag cagaaaatgt
     5821 gatcctattc atagatgaag ttcacgaaat cgtcggtgct ggttctgctg gtgatggaaa
     5881 tatggatgct ggtaatattt taaaaccagc tttagctcga ggagaattgc aaatggttgg
     5941 tgctactacc ttaaatgagt accgcatcat cgaaaaagac gctgctttag aacgtcgtat
     6001 gcaacctgta cgggtagatg aaccaactgt cgaagaaacg atcagtattt tgaaaggttt
     6061 gcaaaaacgt tatgaagact atcatcatgt aaaatatact gatgaggcca tcgaagcagc
     6121 cgcaacttta tccaatcgtt acgtccaaga tcgcttcttg ccggataaag ccatcgattt
     6181 gctagatgaa acaggttcta agaaaaactt gacgatccaa atcgttgatc ctaaaacaat
     6241 cgagaaaaaa ctgcaagaag cagaagaaca aaaagtttta gcttctcgag aagaagattt
     6301 cgaaaaagca gcttattatc gcgatcagat caataaactt caaaaaatga aagaacgtca
     6361 gcttactgaa gaggaaacac ctgtgattac cgaaaaagat atggaaaaaa tcgttgaaca
     6421 acggacaggt attccagtgg gtgaattaaa agaaaaagaa cagacacaac tgaaaaactt
     6481 agcagatgac ttgaaagctc atgtcatcgg acaagataac gctgtagatc gagtagcgaa
     6541 agcgattcgc cgaaaccgtg ttggattaaa caaacagaat cgtccaatcg gctccttctt
     6601 atttgttgga ccaactggtg taggtaaaac agagcttgcg aaacaacttg cctacgaact
     6661 attcggttca caagattcaa tgattcgttt cgatatgtct gaatatatgg aaaaacatag
     6721 tgtctctaaa ttgattggtt ctcctccagg ttatgtcgga tacgaagaag ctggtcaatt
     6781 aacagaaaaa gtacggagaa atccttacag tcttgtcttg ttagatgaag tagaaaaagc
     6841 tcatccagat gttttgcata tgttcttgca aatcttagat gatggtcgat tgacagatgc
     6901 acaaggaaga acggtcagct ttaaagatac gatcatcatt atgacaagta atgccggaac
     6961 tggtaaagta gaagcaaacg ttggttttgg tgcggcacgc gaaggtgtta ctcgttctgt
     7021 attgaaccaa ttaaacaact actttacacc agaatttctg aaccgttttg acgggatcat
     7081 cgaattcagt gcattatcaa aagaaaactt gatgacaatc gtcacactaa tgctagacga
     7141 tgtcaaccaa atgctggcag cacagcaact tcacatcgaa gttcctacga atgtcaaaga
     7201 aaaattagtt gacttaggct atgatccatc tatgggtgct cgtcctcttc gacgcacgat
     7261 ccaagaacaa atcgaagatg gtatcgctga attttatctt gatcaccctt ctatccatga
     7321 gttgaaagca aaactggata aagatggaaa aatcatcgtt acttctaaac cagaacgttt
     7381 ggctaaagaa tcagccgaag aaacggctga ataaatccag ttttatagcg tgagacggta
     7441 tttctttgag aaatgccgtc tcattctttt ttcagaaaag tcaaaatact gttcatttta
     7501 taaaaaagaa attataataa gagaaacaag caattaaaaa tacataaaag aggtgagcgc
     7561 catgaaattg gtaaatgtaa caaacagcca ttcccgtctt gtattaaacc agcttgaaaa
     7621 cactgatgcc catctagtca aggtctacac agccggaaat accactattg tctacactga
     7681 agcccctgaa cataatgaaa ttctgctgat caatgacaaa cgtaaaatcc agccgaaaga
     7741 aatcgaagat gctaaaaatt atttcttaga taaaatcaaa gacgccgttt accacgagga
     7801 tgaaatcaaa gtaatcgaat tggcaggcct tgttgaaatc tcgattccaa aacatgaatt
     7861 aggcgctaca ttagccgtgt aaacaaattt tgaacataat aattaaagag cgtgggacaa
     7921 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcgaaa gcagaagcaa
     7981 ctccttcgga aataagctga aattcacgaa aattgctttt caaatttttg tgaattccag
     8041 cttatttctt ggagttaaac gcttctgtct cagcctcttt ttctttctag ctttttgatt
     8101 tttctctttt cttttgtact tttctctttt cattttcagt tctacgcgtg tctttatttt
     8161 taactttttc ctctttatgg atgattgatc gtactttttg tgcaatttgc tcgtttttgt
     8221 cccagtcttt tacatctaat aatcgacata atcgtaacat ctcttctttt ttctgttttt
     8281 ttctttcacg tctttgccat tctgtttcca tgtgtcacac tctcctttct ttaatcatat
     8341 gtacgcaaaa taatttttat atttttttga ttagacattt ctatgatttt aatatagtaa
     8401 aaagagccgt cacggaaaat ccgtcacggc tctaaacaaa atatgagagg ctgtttttgt
     8461 ttggctattc ttattacttg atgcagggca gcttgtgtca agacttcttt acatcaaact
     8521 ttttaatttt acattgggat atttatccgc aaaccagcgt tctgcaaatt ggttctcgaa
     8581 taagaacaac ggttggtcga aacggtcacg agccaagata ttgcgacttg aactcatctt
     8641 ctcatccaaa tcttctggat cgatccagcg agcgattttg tgtcccattg gagacatgat
     8701 tacttcggcg ttatactcat ttaacatacg atattggaat acttcgaatt gtagctgacc
     8761 aacagctcca atgatatatt cttccgttag atatgtttta taaagctgaa tcgctccttc
     8821 ttgaactaat tgatagattc ctttgtggaa ggatttttgt ttcatgacat tttttgcagt
     8881 cactttcata aacagctctg gagtaaatga agggagttct tcataagcaa cttttagttt
     8941 tccttcgaac aatgtatccc caatctgata attgcctgta tcatatacac cgatgatatc
     9001 gcctgctact gctttttcga cgttttctct cgaatctgcc ataaattgtg tgacattgct
     9061 taatttcagt tttttatttg tacgttccaa ccagacatcc attcctcgtt cgaatgttcc
     9121 agaacagatt cggacaaaag cgattcggtc acgatgggct ggattcatat ttgcttggat
     9181 cttgaatacg aaacctgaaa attcttcctc ataaggactt accatctgat catcttgtgt
     9241 tttgtgtcca taaggagctg gtgccaattc aacgaaagtc tctaaaaaag tctgtacacc
     9301 gaagttagtc aatgcagaac caaaaaatac tggtgtctga tcgccacgag caattttttc
     9361 ttgattaaat gcatctccag cctctttgat tagttctact tcttctaaga cttgttcata
     9421 taaggaattt tcagttagag gatgattttc gggaagcagt ccatcttcat ccaattctac
     9481 taatcgttca tcctgataat tttccggacg ataaaactct acacgattat ggtagatatc
     9541 ataaagacct tctagccctt tacccatacc gattggccaa ttcatcggat aagattcgat
     9601 atctaatagc tcttctaatt cttctaacaa ttccaatggt tcacgaccat cacgatctag
     9661 tttgttgata aaagtaaata tcgggatgcc acgttttttt acaacttgga ataatttctt
     9721 tgtctgtgct tcgatccctt ttgcactatc gattaccatg accgcactat ccacggccat
     9781 caaagtacga taagtatctt cagaaaaatc ttcatgtcct ggtgtatcca agatatttac
     9841 tcgtttccct tgataatcaa actgcataac agaactagta acagaaatcc cacgttgttt
     9901 ctcgatttcc atccagtctg atttggcaaa attacctgtt tttttgcctt ttacggtccc
     9961 ggcttgacgg atagccccac caaacaatag taattgttct gtaatcgttg ttttcccagc
    10021 atccggatgg gaaatgatcg caaaagttct gcgattgtcc acttgttgct ttaattttgg
    10081 attattcata acctaactcc atttcttcca ttcaattatt tatattttct ctaggcacag
    10141 attgtccgat ctcttaaaga aagacaattt catatagggc tgtgacaaaa gccgtgtagc
    10201 agtctctttt tccgagtaaa cggcgttcta gagacagcct atcagcaata agcccaccca
    10261 agccaaaaat acgaaaagct gtttttgctt ggctgctctt attacttaat gcaggatagc
    10321 tttttcacaa cctttgtcaa ctactacaac tgaatcagta tagcatggat tcagcgaatg
    10381 aaaaagccac caaaccataa gagtcaaata tttttttgtc agctgactaa aagaaaagac
    10441 gtgttgcttg tttattcaag caacacgtct ttcataacca agtttccaat tatcttcttg
    10501 gctcgtcatc ttcgaattct tttctgaagt atcttcgttc ttcttcaggt tccgcttctg
    10561 tttcttccgg atcatgaaaa atgacacgga ttttaaggat tcgagaacct tccatttctt
    10621 cagaaaccag cgtaatatta tcgacatcaa acgataactt ttcgccttca tccggaatca
    10681 tgcctaatgc tgtaatcaaa taaccagcca tcgtatctac atcactcata tgcagatcac
    10741 tgtcaaaagc ttcattgaac tcatcaatca gcatacgtcc ttggatgata tattcgtgtt
    10801 catcgatttt ttcataaaga ttctcaactt catctgattc atcatcgatt tctccgacga
    10861 tttcttctaa aaggtcttct agtgttgcta acccaacgac gccgccatat tcatctaata
    10921 aaatagccat ctgattctgc gtctttttca tttcatataa cagatcatca ataaagaccg
    10981 tttcaggaac gaataaaggc tcctgcatga ttttcttgat atctaaatta tcaaagccga
    11041 atttatgggc agcttttagt aaattctttg tatgaaggat tccgactact ttatctttgt
    11101 cttcgttata aacagggatt cttgaatagt tttcggataa aacttcattc acattttctt
    11161 ccacagtgtc gttgatatca atcataaatg catccgttcg tgggaccatg acttctcggg
    11221 caactttcgt atcaagagaa aaaacccctt ggagcatttc taattcttca ttattcaata
    11281 cgccttcgtt ttcaagcata taacgcattt catctctggt catttttgaa tcttcatcat
    11341 caaaagtcat cggcgtgata cgcgccaata aacttgtgga agcagaaagc agccagacga
    11401 agggcttagc tactacacca atcaagcgta tcagccctga agtgaacttt gcgacttctt
    11461 ctgatttatt taaagcaata cgtttagggt acaattctcc aaaaacaatc gatacatagg
    11521 tcaaaatagc cagcacaatg atatttgcaa tattttttgc cgctgtgccg ccacctaata
    11581 ccggagctaa ccgttccgat aaagtattag ctagtgaagc accagacaaa atgttgacca
    11641 aagtgattcc tacttggatt gtcgatagga aattatttgg attctgcaat atttttaaaa
    11701 gcttttgaga tttcacatct ccttcatcag ctttttgctc gattcgattc ttattgatcg
    11761 aaacaacagc aatttcggaa gctgctaaaa aagcattgat caatgtcaaa acgatcaata
    11821 ataaaatctg cgctaacagc gactgactct cagggtcagc attcataatc gcattctctc
    11881 cttataaaat taatttttag tttacgatag aaaaaaacgt ggcactatag ccacgttaaa
    11941 atggtatcac aaagcaattt tctttgcaat aaaaacaagt gtactaaaac tacctacgag
    12001 gtcgtagcaa ttttcttctt gttttcattt tgcttgtctt ctttgacgat tttgattata
    12061 taggaaatga tcgtcttgca gattgcgtaa aaaggaacac ctaagaagat accaagcaat
    12121 ccggcaatat ttccagctac tagaagaacg ataatgatcg ttaatggatg gattttcagt
    12181 gatttcccaa ttacattagg ataaatgata ttcccatcca actgttggac gattagcaca
    12241 accacacaac aaagtaatgc ttttaccgga tcattgaaga ctgttactag aaatgcaggt
    12301 gctagtccta gataaggtcc taaatatgga attaggtttg tcaatcccgc aatgacccca
    12361 aataagaaag cataatccac accaattacc atatatccta aaaatgtgaa ggtaccaacg
    12421 aataaacatt cgattgcttg tccgctaatg taattagcca atgttttatt cagttgcccc
    12481 aataactcca caatttggtt tcttcttttt tctgggaaaa actgttggat gtttggcact
    12541 agtttttctc cgtctttcaa catatagaac aagatgaatg gtgctgtaat gattactacg
    12601 gttgccgaag cgatcgttcc aacgatcgaa cctaaactat tggatactcc actaaggaat
    12661 tgctgaatga ttgtcccgta agaaatgtct aattgctcaa aatatttatt gatatctact
    12721 tccttgaaca aaggcaattc ggctacctct tttaaccagc tttctacctg tttgatgaaa
    12781 tcaggcatat tagatgccaa tgaggaaatt tgctgtacta gacttgggat gacactaagt
    12841 aaaatccaaa taattgctgc aactaaaagg agcagcacaa ttgcgacagc ccatattctt
    12901 ttgatttttg ctttcatcaa cagcttgaca ataggattca ataaatagta aagaaagcct
    12961 gcaatcagta caggtgcaaa taacgtggaa aaaaatgtcc cgatcggttc gaaaataaag
    13021 tttatttctg atgaaatcat gatcaatgca gctatgatca ataattcaag cgaccaaaac
    13081 attagtttag actgtctaag tttttcaaac aatagatttc ctcctttctt tcttactagt
    13141 atatattata ttcgttaaaa attcttttat tcttttttta tttttgaaaa cttgccatac
    13201 tttttatttg ttttattttc cagtatacta tacgaaagga aggtggctag accatgaaag
    13261 ttgtacaaac aaaagataca atgagcaata tttacttaga tgctgtacgg atcaggcatc
    13321 aagtttttgt agtcgaacag ggtgtgcctt tgtctcgaga aatagacaaa gatgaagccc
    13381 attgtatcca cttcgtcctg tactcagata aaaaagaacc gcaaggaact gtacgtcttt
    13441 tgcctttaga aaacggaaaa atgaaattac agcggatggc gattctttct gaatacagac
    13501 accaagggtt aggaaaaata ttgattgaag aagcagaaaa ctttgctaag aatcaaggct
    13561 ataatacgat tttattaggg gcacagtcca cagctgaaac tttttacgaa aaactaggat
    13621 atacagctta cggcgatcct tttgaagatg ctggcatgcc tcatatttat atgaaaaaga
    13681 ctttataaaa atttatttcg aaaaaagcaa aaaacagcaa gcttttgaga aaaatctctc
    13741 actggcttac tgttcttttt tgtgtttact tacgcgacaa ttgcttgtaa cggttatacc
    13801 aaatatcaat atagccttcc gagaacgggc catctccatt attgatccag tcaaccagaa
    13861 tcttcacatt ttcttttagg atgaagtcaa tatcgttcgg gtaattcatc attttgctgt
    13921 gcatctcata ttcatcgaca tccaatagtc gtttctcgcc gtcaggaaat accttgatat
    13981 ccaagtcata gtcgatatat ttcaaggcct catcgtccag caaaaaaggt gaagctagat
    14041 tacaataata ggaaaccccc ttttctctga tcattgctat tacattgaac cagtattttt
    14101 tatgaaaata aacaatcgct ggttcgcgcg ttacccatcg gcgtccatca gattcagtga
    14161 ctaatgtgtg atcattcacg ccgatcatag agtgttcgct tgtttttaat accatggtat
    14221 ctcgccacgt tcgatgcaat ttgccgtcgt gcttgtaact ttggatcgtc acaaactctc
    14281 cttcttttgg aactcccata gcaacccttc cttaagcagc attttgtgct ttgtgtttgg
    14341 gtgttcatta caccgacatc ataattatta tatcaataaa aatgagcttt gcctagaaag
    14401 gattcctatt gtttcgattt ttctctaact gatctaccag tttcatttgg accttaggaa
    14461 aaacgaccga atcaaatgca tcaggcttca accacttcga agttttgttc tcggtaaatt
    14521 cttgttctgc tccctcggtt gcccgtccgt aaaaaaggag aacatgccat ttcagatgac
    14581 taaaaatatg agtaacttct cctaaatgtc gtgtctgcca aacaaagagt tcctgctttt
    14641 caaatgggag attttgctct tcttctgcta ctaggtcatc aaacagatcg atttctggct
    14701 ttgtttccca ttcttttttc aatcgctcat actcctcttg tgtcacttcc atcattggaa
    14761 atgtccacat attcgccagc aatttttggc tatctctttc ttcaaaataa tacgctccag
    14821 aatgattttg aagagctgca ctgatataat aaacgtcttt tggctttgct ttttttgttt
    14881 ttacaggaaa actcgtttgg attcctcgtt tgttagctaa acaaaaggct tggatcggac
    14941 aagtctcaca ctttggagaa gttggtgtac agatagctga acctagatcc atcattgctt
    15001 ggttgaattc acctggatgc ttttcatcaa tgattttccg catcgcttca tcaaagattt
    15061 tcctgctaga agcttttgcg atgtctgctt caatgcaaaa caatctgctg actactcgca
    15121 tcacgttgcc gtcaactgca ggttctggaa gtccaaatgc gatacttgca atcgcgcctg
    15181 tcgtatatgg tcctattccc ttcaatgagc taatttcttc aggcgtttgc ggcatttccc
    15241 catcaaattc tgacatgatc tgtttagcag cagcttggat gttccgggct cttgagtaat
    15301 aaccaaggcc ctcccatgct tttaaaagct tttcttctgg agcatttgct agctcttcaa
    15361 ttgtaggaaa ccattccatg aaacgataaa aataatcgat cactgtgtct actctggttt
    15421 gctgaagcat gatctcagag atccagatac gataaggatc acgattatag cgccaaggca
    15481 ggtttctttt ttcttgttca taccattgaa tgaactgatc ttgaaattct tttgtttctt
    15541 tatctgtcca tttttcccat tctttattca ctttcctctt ccttttccgt aatgaatcgc
    15601 tggatcatat ccaaatcaaa tcctttttga tataagcttt gctttacttt tagatttctt
    15661 tttttaggtt caaaccttaa atttcttcgc catagtttat ctccttgttt gactaaataa
    15721 tcatattcta tttcttgatc tgcttcttgc ggaagatcag ctatcgcttg ttggatcact
    15781 tcttgagaaa agcctttcgt catcaatgtt tgttggattt ttctcaataa ttctttttgg
    15841 ctttttccgt gattttttcc aaacgctttt tcggctgtct gatgtgcatt ttgaacttgg
    15901 tcttcaaatg tatattggct gagcgcttgt tcaatgattt caggtttcaa acctttttgc
    15961 tgcatctgct gcgctaattt ctttggtcct ttgtcactta agcgcatatt cgtgcgcaca
    16021 taactttccc catagaccaa atcatcgaca aggtccaatt cttttaagcg ggctacgatt
    16081 ttatttcgat cttcttgaag gatttccttt tcttttaagt atgttcggat ttctttttcc
    16141 gatcgcaact gataacttaa gtaattcatt gctaggtgaa aaccgaaatc agctccgcta
    16201 ctcttcttga tctcttggat agtttcttcg tctaattccc gtccttttaa taatcgatag
    16261 cgtactaata catcttcaga tacttgtaaa gcttctcctt cagataaatc tacgcgatag
    16321 aaagggcctt tgcctttact gattctcgta acggttaaca taaacatcct cctcgaacat
    16381 atattctcta tcataccaca gaaaatcccc gtaatcaggt attatatgtt agaataaacc
    16441 acagaaaaaa gaaaaaggga gatacttatg gcagaaacaa ttgtcaaaac tggacaaacg
    16501 gttcctttga aaatcaagcg tttaggcata aatggtgaag gaatcggtta tttcaaacgg
    16561 ttgatcatat ttgttccata tgcactacca aaagaagaag tactagtgaa aatcacgaaa
    16621 gcaactcctc gctatgcaga aggagaatta ataaaagtca aaaaaacaag caaagatcgc
    16681 gtagtggcac catgtcctgt ttactatgaa tgcggtggct gtcaattaca acacttagct
    16741 tatcaagctc aattggattt taaaaaggat ctgcttttgc aagcattgga aaaattcaaa
    16801 ccagcaggct ttcgatctta tcaacttttg ccgacgatcg ggatggatga gccttggcat
    16861 tatagaaaca aagcacaatt tcagttacga aaaaataagc agactcaaaa aattgaagct
    16921 ggtttatacg aagcaaactc tcatcagtta gtccctataa cagactgctt ggttcaagaa
    16981 cctcgaacac aaaaagtaat gaatactgtt gttcaactat tgaataaatt tgatgcaccc
    17041 atctatgatg aacggacaaa cagtggaatc ttccgcacaa tcatggttag aatcggtgtt
    17101 aaaactgggg agttacaagt tgtttttatt actcgcagta aaaaattccc gcaaaaaaac
    17161 gcaatgatcc gtgagatcaa tgaacgactg cccgaagttg tttcaatcat gcaaaatgtc
    17221 caggcacaaa aaacgtctct cgtgatgggg gatgaaacga tccacttatg gggaaaagaa
    17281 gccattgaag aacaaatcaa tgaagtgact ttcgatcttt ctcctcgtgc cttctttcaa
    17341 ctcaatcctc agcagaccga attgctttat ggcgaaggaa tcaaagcatt agatgtccag
    17401 cctaatgaaa cgatcgtgga tgcttattgc ggagttggga cgatcggctt aagtgtagca
    17461 aaacaagcca aagaagtacg gggaatggat accgttcctc aagcaatcgc tgatgcaaaa
    17521 aaaaatgcgg aaagattagg atatcacaac actcgatatg aagtcgggac agcagagcaa
    17581 gttctgccta aatggttgaa tgaaggtttt cagcctgatg gtatcatcgt agatccacca
    17641 cgtacgggtt tggataacgc attgatccaa tcattattga aataccctcc aaaaaaactt
    17701 gtttatatct cctgtaatgt ttctacactt gccagagatc tggttaattt aagtaaaaag
    17761 ttcaagattg aatatttaca gtccgtcgac atgtttcctc agactgcacg ttgtgaagtt
    17821 gtcgtgaaga tgacgagact cgctgactaa atgaaagagg ttgtgaaaaa gtctgccctg
    17881 tatcaagtaa taagaacagc caaacaaaaa tagctcttca tgttttatga atactgtact
    17941 tgtgaccgaa gagttaacag gaggacacta tttatttaaa aaaagggttg tgacatagtt
    18001 tttgtcacag ccctttttga ttattattgg atattcacgt ctatcacttg ataaaatgca
    18061 tttgtcgtat cgctgatatt ccatactgct aaaatcacat tatatccttt tcgatcctgc
    18121 ggaagtgtga tcgtttggtt gactgttttt ggtggaacag ttgctttgtc gtctattttt
    18181 gtgatcaatt caaaatcact aaatttcaaa ggttgattag gattccaagt tggtttggta
    18241 atgtagtaat cccaagtact tgtccgatgt tgtgctgtta aattccaagt aatatttaat
    18301 gttcctggat taaccatgtt tttatgccat ctgttagatg tctgttcatc taaaggctca
    18361 aagccgctga ctcctgcact agcaattttt ccatcaatga atgtattttt ggtagcttcg
    18421 atactttgcg gttcccattg tgctcttccg acattttgat ttaagtttcc tgctgctgat
    18481 gttcctaggt atgcacggct tcctggagaa gtaatataac catgcgcaaa acctggaatg
    18541 ctaaaaccga acaaccctaa actaactaac ccaataaaca ataacgtact aatctttttc
    18601 atgtagaaac ctccttcatt tgataaccac attgtaaacg ctttattgta ttaacacaaa
    18661 cattatgctt ttataatttt atgttgaagt aaaaaaggtg aaaaaagtaa gatgcagatt
    18721 ataacagaag tagacgagaa aagtacaaat agaaaacatg agaatcaaat catatgatct
    18781 ttttcaaaaa catcattcat ataaacaaat gttcaacttt ttaataacaa caattatcaa
    18841 tttttttctt acttcacaaa ctaaatacag gtcttgctgt gagccttcat ggtaaactaa
    18901 tattatagaa aggagttagt aaaatgaaga tgataaaaga tattcgtttt tgggtttgtg
    18961 ttataggaat tgtcatatta ggctttttat cagggttgct tagcggaaat cccggaaaat
    19021 attactattc tttgcaactt ccaccatttg caccacctag ctggatattt gggccgatgt
    19081 ggaccttact gtatatattg atgggtattt ctctttattt gttacttaat cacaacaaca
    19141 aaaaacagcg aaacaatctt gtcggtcttt ttgtgattca gttcattttt aattttatat
    19201 ggtctgctct attttttaat ttaagaaata ttttcattgc agcaatcgat attacacttt
    19261 tagttatttt cttgtcagtg cttatgtatc agttgtggct gcatcatcgc ctggcaatgt
    19321 ggctcatgat tccttattat ttatgggtac tattcgcaac tctattgaat tattcaattt
    19381 attttttaaa ctaagcgcta aaaagagacg tcctgtaatt taacacatag aaaaagtgcc
    19441 acctaagtta gattttttgt ctaatttagg tggcactctt tattaaccaa actatttttt
    19501 tctagtaccc acttgttgtt ccatactcat tattctggtc ataaccataa ccattttgtt
    19561 cctgtccagc gtaaggatca taactttgag tatcttgact tggtgtatag tactgacttg
    19621 tatcttctgt ttgctgataa taggtattcg gatcttggta ctgatcatat gtgttttctg
    19681 aataggaaga ataatcggtg tacccttcac tattcgatcc atcaccgttt gtcgaatcgc
    19741 catcttccga atcatcaaag aacatcattg aagcattctc atttttcaaa ttaggtaatg
    19801 tatcgcttgt ttttatattt aattgtttct tcagttcatt ttggatcgaa agaagatcat
    19861 tttttcctaa aatttgatag tagatatcat tgatcatttg tccttcgcct tgcaactggt
    19921 cttgtttgat tgtttcaaac gccggggtgt agttcgtcgc tacatcaagc atgtcatccc
    19981 aatctaagtc cgtcgtcaca ttgttctcaa ctgcttttaa aatttttcta taattgctta
    20041 cgccatctaa acttaaaact ttattgacga ttttcgtcac tacttcccgc tgacgacgtt
    20101 gtcgaccgat atcgccttct ggatcttcgt gtcgcattcg agaataggct aaaccttttt
    20161 ctccattcaa tgtttgttca cctactggta catggacacc atccaaagta aagtcaattt
    20221 tattattcac tttgatgcca ccgaccgcat tgatcaaatc ttccatgcca tccaaattga
    20281 tcgttacata atgatcaata ggaatatcga gcagttgctc aattgaatcc atggccattt
    20341 cgacaccacc aaatgcgtag gcatgattta atttatctac cgttccataa cctacgatat
    20401 tcgtataaat atctcggtcc aaactgatga tcgttgattt tttttgtttc ggattaactg
    20461 ttactaccat catcgtatca gaacgtcctt gttccgttct tcctaatcca ccggtatcta
    20521 aacctaatag caaaaccgaa aaaggttctt tgtcatcaat gcttactctc tcagaacgtt
    20581 tggaggatat tcgattagag tttttagaaa ttttgtttac tgtttggctc gcttctccca
    20641 taaatctgat tccgtatgct gataatccgg caatcagcaa aacgaatacc cctaacaagg
    20701 ttaatagaac tttttgccat cgcttcataa tacacctctg tttcacattt tctaaaatat
    20761 tgtctcatat aactgttcaa tcagcaaatt cactttttaa tcataagaaa actttaaaaa
    20821 acatttttgt gtaacgatta ttatttttta aaatttctca aaattcttaa ctatcatacc
    20881 ataccgtgaa aaagatcgaa agaccgaata cacgcagttc gcaatcgttt tatctttttt
    20941 tatgtatttt ttccagaaaa agcgaacaac aaggtatttt ccaaataatc gtgcagtaaa
    21001 atgatcgcac atacctttcc catcttttta acagtctttg cctaccgttc agattatcat
    21061 tcgatttcac gacaatttct tcctatgact ggtccttttg ttaaacccat cttctattcg
    21121 ttttatttcc agctcactgc atggctctta aaatgactcg aactagtgat tgcattacca
    21181 tcatctttta atggatagat atgctcctct tcaaagtaaa acgattttct tttaaagtaa
    21241 tagaattgac atggtaatga gtatgtatac tagtggtttc acaaatggtc ttttattcaa
    21301 catccaaaaa ctgaaatttc tttaaaatcc attactaacg aagaaaatgt tccttgcttg
    21361 ataattagtt aggacatgtc aagtgaacaa atgcatttac ttagccaaaa aatctaaaaa
    21421 cttcataaat agacaaaaag acacgactct ctaagaagtc gtgtctttat tcaacaaatt
    21481 attataattt agtcacttca gcagcttgag gtccgcgtgc accttcaaca atcgtgaatt
    21541 ctacttcttg accttcttct aggctcttga agccgtctcc ttgaattgct gagaaatgaa
    21601 caaatacgtc atctccgccg tctactgtaa taaacccaaa tcctttttca ttgttgaacc
    21661 atttaaccgt tccgtgttcc ataaatgtat atcctccaaa aaagttcttg caagtaacct
    21721 tgcaagaaca ttatacccaa tttagaaaac gctagcaagc tttcgctctt ttattttcca
    21781 aattattttt aagactgata tgacggagga aatggttatt ttgctgcttc gaaacgtttg
    21841 tttacttcat cccaattaat aacattccag aatgctgcaa tataatctgg tcggacattt
    21901 ttatatttca aataataagc atgttcccaa acgtccaaac ctagaattgg tgtctttcct
    21961 tccatcaatg gagaatcttg atttgcagta gaggtaatag ctaattttcc attttccatt
    22021 acaagccaag cccatccaga accaaatcgt ccagcggctg cttttttgaa ttcttcttta
    22081 aaagaagaaa aatcaccaaa agcttcatta atcgcttctt ttatttctcc tgtaggttcg
    22141 ccaccagcat ttggtgccat gatttcccag aaaaatgaat ggttagcatg tccgccacca
    22201 ttgttacgta cagctgtctt gatatctgtt ggaatagcgt ccatatcaga taataattct
    22261 tctattgttt tttcgcctaa ttctgggtat ttctcaattg ctgaatttaa attcgtcaca
    22321 taagtattgt gatgcttatc atgatgcaga tgcatcgttt cttcgtcaat ataaggttcc
    22381 aatgcgtcat atgcataagg tagatctggt aatgtgtaag tcataaaaaa attcctcctc
    22441 aatgttttct taataatgtc tacattacaa agagtaacaa agagaaggaa attcttcaat
    22501 tgttatgcct agtcgtcttt ttcactttga cctacttctt cttcaaaaac ctcagtttct
    22561 ttaaaaataa acaacttgct gaaaatatag ttcgcaagga taacaataat ttgagtgatg
    22621 attttcgcca catactcatt gctgttcata atattgatca acaataccat tgcccccatg
    22681 tccaatccgt aagaaaggat acggtagaag aagaacttac cgcattcaat aagtgcatgt
    22741 gtaaaattcg gtgattttga atggaatacc caaagtttgt tcgttacaaa agcaaacaat
    22801 acagaacaaa accacgaaat agaattggat aaggccatac ttaaatcaaa atattggcgt
    22861 gcgagagcaa aactaacaaa atttacaatc gtagccaaac caccaaaaaa gagatagact
    22921 agtatctccc aatatccttt tgcttctaaa tatcctttta actgtcgata ctgcttcatg
    22981 agccaaccta ccttattaaa aattcttatt tatcatactc tatatttcaa taactttcat
    23041 ctttatttaa aaaaattaat tttttttgat cctttgcctt tgtctctgct tggatcgtca
    23101 catgtgtaat accatatttt aattttaata aagaaattat acgaggatat atcttttcaa
    23161 tctcgcttag tagctgatct tcaaaatcaa tatgtccgtc gaaaataatt atcttttcgc
    23221 tatactgcca aatatggaca tgatgaacat cctttacccc atcgattgct tcaatttctt
    23281 gttccatttt ttcatagtcg atagcaggtg cactttgtat caaaatagcg gcagcttttt
    23341 tgatcaccat tatcgcttct atcaatatat atatcgaaat gatcagtgta ataactggat
    23401 cgatccagta gatatcgaaa aaacggatca aaattgctcc gataatcaca cttaccgaag
    23461 acagtgtatc acttaacaaa tgcaaataac tagattttat attcaaactt tcatctgctt
    23521 cttgtcgtaa taataatact gagaacaaat tcgcgagcaa tccaataact gctactgtta
    23581 gcatcaaatg actatttatc ttttctggtg aagtgaaccg cttgaatgct tcaacggtta
    23641 aaaacaagga taatatgatc aatatgaatg agttgatgaa agcactcaat atttctaaac
    23701 gctggtagcc atacgtacgt tttttatttg cttcttttcg ggccattttt tgtgccccgt
    23761 aagaaaaaat aattgccaat gtatcactaa ggttatggaa agcatctgaa acaagagaca
    23821 aactccctga cataatccct ccaataaatt ctgataaagt gatcaccgca ttcaaaacca
    23881 ctactccaaa tagttttttt gatgatctct gtggctgtgt aggcactatt ccttcctcca
    23941 ttttatttat attggatagt ctttagacaa gaataacatt tttttgatat ttcaccaatc
    24001 attcagctgt ttccttaaag cacttgtatt tcacttgata cttcgctaga attgcaagtg
    24061 atgacactac tagatgagga gtacttatga caacaaaaca attaattatc agttccttta
    24121 tacgattcaa agacctaaag gaggcgagaa atgtcccatt ttggaaagcc attgtctatc
    24181 ttttagtttt gagtataatt atggctttgc caatctcttt tcaagttttt caagtcttaa
    24241 acaacattca attggatggg caaaagattg ctactcgcat tcctgatttt acaatccaaa
    24301 acgggcagct tcaaaccgaa gaaaaagaag gattcattta ccaaacaaac tccattatct
    24361 tcacatttga tccagaggga aaacgaacag aacaggacat ctctactgat ttgatgggga
    24421 attttgttag tgtcgggatg ttaaaaaaca aacttatcat agctcttcct aatacaggca
    24481 cgacttctgc tttgttgaac aataaccaat tagaacttcc ctacaccaat gaatctttaa
    24541 aaaacttaac aggtaagcag ctccgttctt ttttaagtga agcatctata ccactttgga
    24601 taaaagtcct gacatttata ttttctattt atcctagttt tctgaatctg ctgatcactt
    24661 tgctatttac caacattgct gcttttctct atgcacgctt tcgactaaca aaagctactt
    24721 ttcttgattg tttaaaaaca ttgatctatt caatttcatt gcctactata attgcaacaa
    24781 tcttgatggt ctttcttcct tcttttgaca ctagcgcctt cattgctttt gcaggaatct
    24841 ttatttttgc tcaagctgtc aaaggatggg caaaaatatc gatcaattaa gaaataaaga
    24901 caactcgtta tttctacttc aatagaccct tttagaggtt gtgacatttt tttgtcacag
    24961 cccctttttt atttgaaaaa tatttctttc tcaaaaaaca agcaaggcgc ttcaaagttc
    25021 ttcttgtatg cgctacactt agagtaaaga aaggcgggaa attaactatg tcagaaagaa
    25081 tcatttatgc agatcgtcca tttcgtgatg aatttatcga agaaatccat actatagcgc
    25141 ctggttatat ctttaaaaca gaattacaac cagaggatct acaaaatgta gagatcagtt
    25201 tgggctggaa ctcagactac caagaaaaac tattagcctc ttctaccttg aaatgggtcc
    25261 aatctatctc agctggtgtt gatcagctac cccttgagac tttttcaaag aaacatattt
    25321 tactttcaaa tggtagtggc atccacagtg aatcgattac ggagcatgtc ttaggaatca
    25381 tccttgggta ttctcgtggt ctttttcaag cacaaaaggc acagagtgac atgaaatggt
    25441 taggttcatc ggtccattac caatctatcc aagggaaaaa aatactaatc attggaactg
    25501 gccatattgg aaaaatgatt gcaaaaaaat gcaaagcatt agacatgaac tgctatggaa
    25561 tcaatacatc cggtcatcca gcagaaggaa tggaaaagac tttttcttta aatcaactaa
    25621 aggaagttct tcctgaagta gatttcgtag tcaatatctt acctctaacg gaggaaacaa
    25681 ctgggctctt tgatcagcat atgtttgaac actttgatcc aaaatctgta ttcatcaatg
    25741 ttggccgtgg tgcttctgtt aagacacaag atctggtgca ggctttaaat aaccagcaac
    25801 tttcctttgc agcattagac gtttttgagg aagagcctct tccacaagat catcctcttt
    25861 ggaaaatgga caatgtactg attacttccc acattgcagg tttgacacct gattttcaaa
    25921 agaaattaat ggctattttt ttaaccaatc tgaaaagcta ctttgccacc catgagcttc
    25981 aaaccaatca agtaaaattg tctgcaggat attaatagct gaaaacaata ttttcaaaag
    26041 aaaaaagaga aggtgacaaa aattgtgtca ccctctcttt ttttattgtt ttttaaagtg
    26101 ataggttggc tcctccaggt tgggatcata atcaacaagt aaatcatatc ctttaaagaa
    26161 ccattcatct gcttcctcga taaaaaaaag tgtcccatcc atttccactt tctttacagg
    26221 atgttctggc tgttcaactg acattccaat cgaaaaacca tcatgaacct ctgttttgcc
    26281 gtagactttt ccaaaaaaac gtattccgta agtttctggc agatcaattt ctgagtcaaa
    26341 ccacttttgt gcttttggcg ttaccgttaa tttcatccca acaacctact ttctcttttc
    26401 tttctattga ttcatcttat cgtctagaat atccacatcg cctgtctctc caataaccag
    26461 tagattatca ttttcacgaa catattcatc tgctgcagga gaagcgataa ccgtttgatc
    26521 tactcttcgt atggcgacta ctgttaagtc aaaacgttgc ctgaaattta attcagctaa
    26581 tgttttgttg aaaaatttag gattggagac tcggatttct gctaaagaat atttatctga
    26641 caactctagg taatctaaaa tattctttga cactaaatta tgcgcaatcc ttattcccat
    26701 gtctcgctcg ggatggacga cgcgatcagc tccgatcttt tcaagtactc tggcatgata
    26761 ctcattttgg gcttttgcta aaatatttgg tacgcccatt tcctttacca tcagagtaac
    26821 taagatactg gcttgaatat cttctccaat agcgacaatt acatgatcga aatttcttat
    26881 gcctaatgat cgaagtgtca tttcatcctg tgcatttgcc acaacagcat gagtggctat
    26941 attcatatat tcattgaccc gatcttcatt actatcaata gccagtactt cttgaccagc
    27001 ttcgatcagt gttcggcaga tacttccgcc aaatcgtcca agacctacaa ttgcaaaatt
    27061 ttgtttcacc gttttcctcc tttagtatct tcttttctca gtataacaaa gcctttacaa
    27121 aaacaaaagc aagcatcatt attgtaaaaa agccaagaaa aataatagtt attttctcag
    27181 cttttgatta tcctctttat catcgttttt atttcaccaa accatgtttg aatgcataga
    27241 tagcggcttg tgtacggtct tccacttcta gcttagccaa tatattggaa acatgtgttt
    27301 ttactgtttt cagtgtaata aacaattcgt ccgctatttc ctgattactt tttccttcag
    27361 aaatcagcat taaaatttca ttttcccgat tcgttagttc ttcatgtaat acaggctcat
    27421 ttcgccgact cattttttcc atcatttttg ttgtcacttc tggttctaat actcgctcgc
    27481 cacgttgcgt tgcccttata gcatcagcaa tttcatgtgc ggtagaggtc ttcaacaaat
    27541 accctgctgc acctgcttca atggcaggat aaactttttc gtcatcaata aaactggtta
    27601 cgataatgat tttagcttct ggccaatctt ttaagattgc ttttgttgat tcgataccat
    27661 ccatttcttc catgactaag tccattaaaa tgacgtccgg tcgaagtgtc atcgccttct
    27721 catagccttg tcgtccattt tcagcttctc caattacttc aatgtcttct tgaatagata
    27781 aataagaaga gacgcctaag cgcaccattt catggtcatc tactaataaa acttttatca
    27841 tccttatcta tgcctccttc atcaaaggga ccttgatttc tacacttgta ccttgacctt
    27901 taaaactaat gatttttact gttccaccaa taccagctac tcgttctttg atattgttca
    27961 atccataact tcccgttttc gtttcattca tattaaaccc tgttccgtcg tcaataatac
    28021 gtaacaaaag attattgtct attttgtgca aatatacctc taattcattg gctttagcat
    28081 gtcttaatgt atttgataac aattcttgaa cgattcggaa caagtgatcc tcaatggaac
    28141 tagatagttt tacatcttct acatcccatt tcagcgaaat ctggatttta ttttgcaatt
    28201 ccttcaataa ctgctcgata ccttgcttta aacttttctc ttctaaattg actggacgta
    28261 gatgaagaag cagcgcacgc atctcagact gggaagcgtt gatgatctct gctaccattt
    28321 tcaactgctt gcgaaacatt tctggtgtct cgcttttttc tgcttgctcc gtcaatgccg
    28381 acatcatcat cattgctgca aacaattgtt gcgaaactga atcatgcagc tcacgggcta
    28441 atcgatgtct ttctaattct aaaatttctt ctttggtttg tccatctaca tattggggac
    28501 ggctcgttac aatttgtaat tcactagata cttcaatcat tttttctttt atcttagtga
    28561 tttccttatc aatatctttg atgtataaat cgtccgatgc acttgggatc ggaagaagca
    28621 acaatttgga ttcataattg ccagaagaaa gtgcacgcag cttttcttcg attttcccgt
    28681 attttgtctt ttgaataagt gataataata gaaagacaat taatcctaca cctaaggaaa
    28741 tggctaacaa atggaagata agcggaacat ataataaacg tgcacgcagt aattctcccc
    28801 accaatgact ttgattgctg gcataaaaat aagtgaaaag tgaaaataga ataataagga
    28861 aagccgcaat ccccgaataa acagctagca tcgctctgga tatttttccc atcatattcg
    28921 tatcacctcg acatctccaa tcaaggtatt agtaataatc ttcaatctac gagggttttc
    28981 atcataatca ctgctgtaga ttttgatttg ttcatttttc aaagaaaatt gctcttcttc
    29041 aaacaagaca tttcctacta atgtcgcatg ctctaatcgg atggctacgc ccaaaggtac
    29101 taagatccgt gttctgccta tcccttttct tacaatcaca atattatcat cttttggcaa
    29161 aagcgtattg cccaaatcta tgatagtatc accagaaatg acggcgatgt tgatatcgtc
    29221 ccattcatag acgtcgtttc caatacgttg gttaccgaat aattgctgtc ttttccgctc
    29281 attattatgt gtttttaatt gctctgtttg gatcatcatg atctgtttct ttcgccaaaa
    29341 agcatttttg gttaaatcta tccctgaaat ctctacacct ttcagaccaa taaataaaac
    29401 ggcaaataca gccatcatcc ataaagcagg actgttgact aagctaaaaa aaatgaccaa
    29461 acttcctaat atcaattgaa aattttgaaa tttagtacga ggatgtttgc gcatagctag
    29521 atatatattg aaaataccga atatcactaa aagcaaaagt ccagtattgt ttacgatttg
    29581 ccaaacagca aataacagca gtagtgcttc aactaccaca aaaaaacgcc aagaactatt
    29641 catcgctctt tctccctcct gacacattct catttcatca tacctatttt tttaactgtt
    29701 ggctatagga ctttagatgt aagatcgttt gttgaaatct aaaatacaca aagagaaaaa
    29761 gatctagagt gtatcatcag taagatgaac tctctagatc tttcagtcag actacgcttg
    29821 ttctactttg acgattttaa ctaacatatc gccacctgga gtagcaatag ttacttcatc
    29881 atttttacgt ttgccaatca atgcttgcgc aataggagaa tcattggaaa ttttgccaga
    29941 aaacggatct gcttcagcgc ttccgacaat cgtgtactct tcttcttctc catctggtag
    30001 ttcgatgaat gtaactgttt taccaattga tacctcatct gcatctacac cgtcgttatc
    30061 gatgatttga gcaaaacgaa tcatattttc aattgttgtg attcttcctt caacaaatgc
    30121 ttgttcatct ttcgctgatt catattcaga gttttcggaa agatctccga aaccgcgggc
    30181 aattttgatt cgttcaatga tttctccgcg tttgactgtt tttagttctt ctaattcttt
    30241 ttctaatttt tctttacctt ctagagtcat tggataaact ttctctacca tgtgtaacgt
    30301 ctcctttttt cgataaaata ccgcaaaagg taatcttttg aggaatatag tccaaaaaag
    30361 attaccacgc ttttcttcaa atgtaaatgt ttttctaaaa atgatcaatg tctagagcct
    30421 gtttttctaa gaattattta catatttttc cactaattcc atatgttctt cataagtttt
    30481 agcgaaataa acatttccag tgctcgtatc tgctacgaaa taataatagt cattttctgc
    30541 tggttctaat actgccttga ttgcctcttc gcttggattg tcaaaaggtc caggtccata
    30601 gccggtattg gtatacaaat tatatggtga atctacagct gtatcttcat acgtcactaa
    30661 ttctttgtgt tcacctaatg cgtataaaac agagatatct gactgaagtg gcatatttgc
    30721 tttgattcgg ttaaagaaga cttgtgcaat gtttttacga tcattttctt ttacgccttc
    30781 tttttcaact agagaagcta gagttaaaac ttcttgtaca gtcaaatttt tctgcttgat
    30841 agctgaataa tagttttgca tgaccgtatt cgtcttgttc accatttcaa tcactagatc
    30901 cttaagcgaa gtactcgtgt aataatcata tgtggctggg aataagtaac cttccaaacg
    30961 gtattttgtg ttctcagctt tagatgcact ttccaacagt tctgggaatt tttggtgcaa
    31021 ctcgttaaag aaagtctcat cattcactaa atctaaaaat tctttcttgt ctttaccagt
    31081 taccttcgct acccgttcag caatctgatc gatatcgtac ccttctggaa tggcaatttt
    31141 cccatctgca acttttgttg gctcagaagt accgccttct tgcaactgtt tgccaatctc
    31201 gtcaagagtc atattaggcg ctaactgata atagccagct tgaaagccag ttaaattttt
    31261 aaattttgta taataattga aaacaatccc gcttttaata atattgtcct tctccaaaat
    31321 ctcaccaatc tgcttgttag aagagccact cgggatctcg acttggacta attggtcatc
    31381 tgatttatct aaaggcttca acccgctatc tacataacga tacacggtaa atccaagaaa
    31441 tccgccaata atcaataatg taagagcaat cactaaaatg atcttcctca caatcttatc
    31501 ttctttttta cgcagatttc tccgcttgtc gattatatct gctgtagctg ccttactggc
    31561 ttctttttta tctttacttg ggtgttgttt gtttcctgac aaaacaactc ctccttacta
    31621 tcaagttcgt aactttattc attatacatg atatttgaat tggcgtgaat gattttattt
    31681 aaatattcta tcaaaaa
//
LOCUS       DADVXB010000016        30802 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.016, whole genome shotgun sequence.
ACCESSION   DADVXB010000016 DADVXB010000000
VERSION     DADVXB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.016"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(147..311)
                     /locus_tag="KB902_000563"
     CDS             complement(147..311)
                     /locus_tag="KB902_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807415.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            606..1934
                     /locus_tag="KB902_000564"
     CDS             606..1934
                     /locus_tag="KB902_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBB6807416.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2136..2969
                     /locus_tag="KB902_000565"
     CDS             2136..2969
                     /locus_tag="KB902_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBB6807417.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2985..3722
                     /locus_tag="KB902_000566"
     CDS             2985..3722
                     /locus_tag="KB902_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBB6807418.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3877..4845)
                     /locus_tag="KB902_000567"
     CDS             complement(3877..4845)
                     /locus_tag="KB902_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBB6807419.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5077..5910
                     /locus_tag="KB902_000568"
     CDS             5077..5910
                     /locus_tag="KB902_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBB6807420.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5944..6783
                     /locus_tag="KB902_000569"
     CDS             5944..6783
                     /locus_tag="KB902_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6807421.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6809..7369
                     /locus_tag="KB902_000570"
     CDS             6809..7369
                     /locus_tag="KB902_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6807422.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7568..9289
                     /locus_tag="KB902_000571"
     CDS             7568..9289
                     /locus_tag="KB902_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBB6807423.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9454..10596
                     /locus_tag="KB902_000572"
     CDS             9454..10596
                     /locus_tag="KB902_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6807424.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10612..11823
                     /gene="thiI"
                     /locus_tag="KB902_000573"
     CDS             10612..11823
                     /gene="thiI"
                     /locus_tag="KB902_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBB6807425.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12396..13043
                     /locus_tag="KB902_000574"
     CDS             12396..13043
                     /locus_tag="KB902_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6807426.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13172..13388
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13436..16081
                     /locus_tag="KB902_000575"
     CDS             13436..16081
                     /locus_tag="KB902_000575"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBB6807427.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16391..17704
                     /locus_tag="KB902_000576"
     CDS             16391..17704
                     /locus_tag="KB902_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBB6807428.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17694..18347
                     /locus_tag="KB902_000577"
     CDS             17694..18347
                     /locus_tag="KB902_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6807429.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18402..19094
                     /gene="radC"
                     /locus_tag="KB902_000578"
     CDS             18402..19094
                     /gene="radC"
                     /locus_tag="KB902_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6807430.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19244..19444
                     /locus_tag="KB902_000579"
     CDS             19244..19444
                     /locus_tag="KB902_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6807431.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(19698..21377)
                     /locus_tag="KB902_000580"
     CDS             complement(19698..21377)
                     /locus_tag="KB902_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6807432.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(21379..21591)
                     /locus_tag="KB902_000581"
     CDS             complement(21379..21591)
                     /locus_tag="KB902_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBB6807433.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21984..23714
                     /gene="efrA"
                     /locus_tag="KB902_000582"
     CDS             21984..23714
                     /gene="efrA"
                     /locus_tag="KB902_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBB6807434.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            23711..25471
                     /gene="efrB"
                     /locus_tag="KB902_000583"
     CDS             23711..25471
                     /gene="efrB"
                     /locus_tag="KB902_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBB6807435.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            25566..25763
                     /locus_tag="KB902_000584"
     CDS             25566..25763
                     /locus_tag="KB902_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807436.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25916..26401
                     /locus_tag="KB902_000585"
     CDS             25916..26401
                     /locus_tag="KB902_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBB6807437.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(26505..27098)
                     /gene="clpP"
                     /locus_tag="KB902_000586"
     CDS             complement(26505..27098)
                     /gene="clpP"
                     /locus_tag="KB902_000586"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBB6807438.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            27278..27805
                     /locus_tag="KB902_000587"
     CDS             27278..27805
                     /locus_tag="KB902_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807439.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27896..28633
                     /locus_tag="KB902_000588"
     CDS             27896..28633
                     /locus_tag="KB902_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6807440.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            28637..29554
                     /gene="miaA"
                     /locus_tag="KB902_000589"
     CDS             28637..29554
                     /gene="miaA"
                     /locus_tag="KB902_000589"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBB6807441.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            29556..30785
                     /gene="hflX"
                     /locus_tag="KB902_000590"
     CDS             29556..30785
                     /gene="hflX"
                     /locus_tag="KB902_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBB6807442.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10172 a         5271 c         6573 g         8786 t
ORIGIN      
        1 ctgccggagt aaataaagct tatgcaaaga aaaagaaatc caatcacttg ggtttctttt
       61 tcttttatta ttatgatgaa tcaagctttc tgtttttgtc acgtatgttg taatctttac
      121 gaaagagtag agttggctac tcataatcaa ccatacttcc catcatcgct aaatacgaaa
      181 taaatcagca ttcctacacc aatcaaagca caagctgcac caagaaaagg gatgacattc
      241 ccaaagttat ctgtattcat aagtatgcca ccacccacaa acaaaaagcc gccagcaatc
      301 aggtttttca ttttattcat ctcctttctt acgttatagt atttccttct ttcaatgagt
      361 attttgaaag ctatcttatt gtatgatgtt cttctaggcc tcttctttat tatacaggcc
      421 attttcgtta tctcatagaa atattccttt ttatctgaaa actattgtat accgtatgac
      481 atttttcttc atgaagttgt aagtatattc tcattcaaat gaaaatttca tcatagaaga
      541 gattgtattt ctaaattctt aagagtaaaa tacgaagtat aacttggatt tggaaggatg
      601 attggatgaa agctattacg cctgatatga caacaaaatt taacaaacag tttcaagcaa
      661 atatcaaaca gcaggcattg cagcgggcag ttgtgaagaa cggaattact gcttctgctg
      721 aaaatgtttc agcacatgtg gagaatacac cggtattttc tatagatttg gctacgggga
      781 aagtggctaa tcaaatgcaa tcggggcgtt gctggatgtt tgctgcactg aacacattcc
      841 gtcataagat gctgaatcaa ttccatttaa aagagtttga attatcacaa aattacactt
      901 ttttctggga taaatatgaa aaggcaaatt atttctatga aaacatcatt gcaacaggaa
      961 aagaggcaat cgatagccgg aaagtagctt tcttactcgc tactcctcaa caagatggcg
     1021 gccaatggga tatgatcgtt tcattattcc aaaaatatgg cgttgtgcct aaatcggtga
     1081 tgccggaaag tgcgaatagt tcaaattctc gagatttgaa taactacttg aacaaattac
     1141 tgcgtaaaga tgcagtagtg ttacggaaaa tggttgctca aggagaaaca ttagacgcta
     1201 ttgaagaaaa gaaagaagaa atgctagaaa gcatttataa cttcttagct atctcattag
     1261 gaacacctcc aaaagaattc gattttgagt accgcgatga agaaaagaac tatcatcttg
     1321 accgaggact gacaccacaa attttttatg ataaatacat cggtgtaaaa ttagatgatt
     1381 atgttagcgt gatcaatgca ccaacaaaag acaaaccatt caatcgttct tatacagtag
     1441 agatgctagg aaatgtcgtt ggcgggaaag aagtcaaata tctgaatgtt gatatggaaa
     1501 ctttcaaaaa attagcgatt gctcagcttg aagaaggaga atctgtttgg tttggttgtg
     1561 atgtaggtca atcttctact agaactagtg gcatcatggc cttagatgct tattcaatgg
     1621 atgatctatt tgatacggat tttacaatga ctaaagctga acgtttagat tttggagaaa
     1681 gtctgatgac ccatgcgatg gtattgaccg gtgttgactt agtagacggg caatcaacaa
     1741 aatggaaagt cgaaaatagc tggggcgaaa aagttggaaa gaatggcttc tttgttatga
     1801 gtgatgcctg gatggacgaa tatacgtacc aaatcgttgt aagaaaagat ttattgacga
     1861 aagagcaatt aaatgcgttc aatgaagaac caattgttct atctccgtgg gatccaatgg
     1921 gtgctttagc atagacgagt atttcaatga agagtatgta gtaaagataa aaagagctgg
     1981 cttaagccag ctctttttat ctttaaagtc cattccctgt tttttatggt ccctgtgcta
     2041 taattctaaa taaaggataa ggattggaaa taatcctttt atcattaaaa atatgatgac
     2101 gaagtagaat aaaattggga gtagggggga aagtcatgga tatccaaact gttttatctg
     2161 atctgaaatt aaatggtaaa gtgattccag ttgttggtgg cgatgttaat cagacctatc
     2221 gtataaaaac cgaacatcgt gcttattttt taaaaatcca tccgaatgta aaaaaaggat
     2281 tttttgaagc agaagtagac ggattaaaag aactgtcagc attcgtacgt gtaccggata
     2341 cgtatatgct aggtgaaaca agtgaaggcg cttatttgtt aatggaatgg atcgagccgg
     2401 gaaaagggga tcaacgagat cttgctgcag ctttagctaa tctccatcag caaacagcgc
     2461 cacaatttgg ttttcgtaaa gataactatt tgggtacact tgttcagaaa aattcttttg
     2521 aagaagattg gtggactttt ttctttaaag atcggcttga atcccagatt tctttggcag
     2581 aagaaacgaa tcgatggaat gtacagcgtc aagaaaagta tctgcgattt aaagaacgtg
     2641 tattgaaatc ggttgaacca aaaaagatca ctccacgcct cttgcacgga gacctgtgga
     2701 gtggtaatgt gttctttgac cagcaagggc atccagtttt tgtcgaccca gctgtttctt
     2761 atgggaatcg ggaacaagat attgcaatga gccagttatt cggtggtttc cgaccggaat
     2821 ttttagatgc ttatcaaact atatttccat tagaaaaggg atggaaagac cgactgccga
     2881 tttaccagtt atattatctt ttggcacatt tgaatatgtt tggagaaagt tacggttccc
     2941 aagtagatca attactagaa aatttttaag aggagggcgt gtttttggca aaaaaatata
     3001 ccaaaaagca tgaagtttca tattatgagt gtgacatcaa ccaaacgatg acatttcctt
     3061 cgatgttagg agtagttatc aaaacgtctg aagatcaaag cgaccagttg ggaagaggca
     3121 gtgaattcgt caatagcttt ggacttactt gggtcatcac gaattattcc atggagatta
     3181 atcgtctccc tagagtcggt gaagtaatct cagtaacgac tcaagccatg gagtacaata
     3241 agtttttctg ttatcggaac ttctggatcc atgatgaaga tgggaaagaa ttagtcaaaa
     3301 tagaatctgt tttcgtattg atggattttg tgaatcgaaa aatgagcagt gttaatgaag
     3361 agatcattgc tccttttgag agtgagaaga tcaagaaaat caagcgtcag gaaaaaattg
     3421 aaaagattga ttcgggcttc atgttgccat atcgtgttcg tttttatgat atcgatagta
     3481 atcagcatgt taataatgcg atgtatttta attggatcat tgacgtatta ggatatgact
     3541 ttttgactac gcatgttcca gaaaaagtaa ttattcgatt tgataaagaa gtagagtacg
     3601 ggaatgagat cgaaagccat tttgaacaaa tccctatcga aaatggtgtc aaaacaaaac
     3661 atgaaatccg aatgcaagaa cagctgtatt gtgaagcaaa tattatatgg aaaaataaat
     3721 aaaaaagagg ttgtgacaga agggggcaac ttcaagaaat aagaagaaat ttacgaaaat
     3781 tgtttctcaa atttttgtaa attttcgact tagttttcga agaagctatt tttgtcacag
     3841 cctctctttt taagtttagc tattagataa tgatgtttag ttttggataa acgaaatcaa
     3901 ttcttcaccc gacaaaccat agtttacagc aatcaatagt tttaaacgtg ctttttgact
     3961 attaatactg ttacagaaaa taatccccat tttttctagt tcttttcccc cgccttcata
     4021 atcataaaca ggctctgcga ttccattgaa acaacgagaa acaagtacta cagggatttt
     4081 ttggacaaga agcttttcca aagcagctaa ggcttgtgga gggagattcc ccgcacctaa
     4141 agcttcgatt accaaaccgt ctactttcgt atgggcgatg gcttccaata agtccccttg
     4201 catcccagca tatgctttaa cgatcgggat agtcccatct acagcggaaa tgtccagtcg
     4261 ctttgtttct aaaagttcct gcaagaataa aattcgattc ttagttacta agccgatggg
     4321 acccaatgta ggtgttcgga aagtagcaac atttgtggta tgggtctttg tcacgtagcg
     4381 tgcagaatgg atctcatcgt tcatgaccac caaaaccccc ttatctagcg cttcttcaca
     4441 acttgcgaca cgaatcgcac tttcaaaatt ataaaggccg tcacttccaa gttcattact
     4501 tgaacgcatt gccccagtca aaacaattgg taatttgttg ccaatcgttg tatcaagaaa
     4561 aaaagcagtt tcttctaatg tatctgtacc gtgtgtgatc accactccgg atatacctga
     4621 tgcataagcg gacaagatac gttcttttaa taccaacatg tgagaaggca tgatgtgtgg
     4681 tgagggaaga ttgaagatat cttcaactaa taattctaca tgcttgggga ttgtgatttc
     4741 tgcatctaat aatgggtttg ccacatcagg actaacaccg cccgtgagca tgttttcttt
     4801 catggcgatc gttccgccgg tgtgtagtac aagtattttt ttcattttac agacttcctt
     4861 acgaataatt ttgcatagcc gttaaatctt attgtatact atataaaaga gttttgctat
     4921 cagtgaagaa taacgaatag cctaacttat cataaaaaag ctgaccttat taaaatggaa
     4981 aagactcaac cttgacctcc taatacaatg gagtatctgg ttgagtttct tttacaagaa
     5041 agcagccaag gaaatcaatc acgaaggtgg ccggaaatga tcagaatcgg attaacatcg
     5101 tttaaagaac atgacaaatt aactggtaaa aagaataaca ctctttatga atatgcaggg
     5161 tttctaccct tagtggaatt agatactgcc tattatggaa ttccccgaaa gtcctcagtt
     5221 gagaattgga taagtgaagt acctgaatca tttcgctttg tagtcaaagt ctatcaagga
     5281 atcagcggtc aaggagactg gaagccttat tatcagaccg aagaagagat gattgcgcat
     5341 tttttagatg ttatgtcgcc aatggtagat gctggaaaga tgttttgctt tttagtccaa
     5401 ttcccctcat cattcaaatg tacgaaagaa aatgtccagt acttgcgcaa acttagaaag
     5461 tggtttgagg gttatcctgt ttctatagaa ttgcgggatt attcttggta cagcgatgaa
     5521 tttcttgaac gtacaagaaa ctttatgtct agagccgctt tttctttagc catcatcgat
     5581 gagccacagt tgctgaatac aacgattcct tttgatccat ttgtcaccaa tccgaacttt
     5641 gctctttttc gattccatgg taggaatgcg caaggatggc aagcaaatga taaagagtgg
     5701 cgtaaaaaaa gaacgttata tcgttattca gaaaaagaac tgcaagaact agcacatgaa
     5761 gtcaaagtag ttgattctaa gacaaaagag gtaggtgtga tttttaataa taattctggt
     5821 ggtgatgcgg ctgaaaatgc attagcactg caaaaaatat taaatatcaa gccagatgga
     5881 ctcaatccaa cccaaatgga tctgttttaa gggcttattt tattcaagaa aggggcgaag
     5941 tctatgatca aagctatttt ttttgatatt gacggaacat tggtcaccaa tcgttcaaaa
     6001 gcgttggaat caacaaaaca agcaattgaa tatgctcgga aaaacggcat tttatgcggt
     6061 gtagcaacgg ggcgcagccc agtaaagatc aaagaaatca ttgatgaatt ggaattagat
     6121 atgtatgtcg tgtataatgg tcaactggtt tttactgcag atcgcacgat tatcgaccac
     6181 ccttttgaac aaaaagtatt ggaacatatt gttgaatttg cagatgagaa ccatcgacaa
     6241 atcgtttttg gtgcgagaaa tcggttagat ggatcaacga cgatgctatt aggacaatcg
     6301 atttttatca agcgactagt cagcttttta ccgcgtaaat tcccggtacg tctgatgaaa
     6361 aaaatcctcc aggtttttag ccctcaccga caaaaggatc gttatgaaac gttagagata
     6421 ttaaaagaac caatttatca atgtatattg ctcagtccgg agtcagaaca gaaaaagtta
     6481 gaacatcgct ttcccgagtg tacgtttcag cgttcaaata cgtatactgt agatatcatc
     6541 ccaaaaggtg gttcaaaatt actaggcatc caagctttcg caaatgctgt cgaaattgaa
     6601 atggaagaaa ttatggcatt cggcgatcat tacaatgata tcgagatgct gaaaggtgta
     6661 ggaattggag tggccatggg gaatgctcag atcgaagtaa aacatgctgc agactttgtg
     6721 actcaatcaa atgaagaaga tgggatatac gaaggactga aacacttcgg tctgatttat
     6781 tagtcaatga aagaaggaaa aaatcagtat ggaagcagag acaccttttc aaaaagtaga
     6841 aacattccac aaaacttttg atccaagaag accagagata cccacggctt ttacagaaaa
     6901 tgaagctcat acacgtgctg cgttcaaaat agaagaactt gttgaatttg ttgcagctac
     6961 ttcacctaat aaagaacaac tgcatgaagc tgttatgctg ctgcacgaag cattagataa
     7021 agcagaagaa aaaatacttg gtaaaacaca gtggggaagt gatccgctgg ttgaacaagt
     7081 agatgcactg acagatatcc tttactttac ttatggttct ttttcattac taggaatagt
     7141 gcctgatcga atattcgaaa tcgtccatca ggcaaatatg gggaaattat ttccagatgg
     7201 aaaacctcat tatgaccctg taacaaataa agtgttgaaa cctgaaaact ggcagatgga
     7261 atatgctcca gaacctaaaa tcgcggcaga aatccaacgt cagattcaag aagcgattgc
     7321 taagaagaaa tccgctgata taggcatgtg cacaaatgaa aaagagtgat cagagtttca
     7381 ctatttttgt tatctttata cgatggaaaa acaaaagatt ttcgtttaag ttagtgaatg
     7441 catgaaaata gtatgctata atctagaata gatgtctttt gcacgagaga cgtattattt
     7501 ggatttatgc caagcagaac gccatctgtt gcataaaaga tgcatactga aaacggagga
     7561 accataaatg ggaaataatg ttatcatcgg aatcgtcatt gcaatcatta tagtcgccat
     7621 tgtcgtcttt ttggttagtt acttgatgaa gaaaaaaaac caagatcgat tggatgcctt
     7681 agaaaaacgc aaggaagaat tatttgactt gccagtgatt gaagaagtcg atgatgttaa
     7741 aaaaatgcat ctggttgggc aaagccaaaa tacctttcgt gaatggagtc aaaaatggaa
     7801 tgacatatct acttcctcgt tcgctgaact agaaagtcaa attttcgaag tggaaaacct
     7861 caatgaaagt tttcggttct taaaaggaaa aaaagcagtt gttgaagcag aagctacaat
     7921 ggaccaaatg gagaaacaag tgacggaaat ccgtgaaggt ctaaaggaat tgcgggaaac
     7981 ggaagaacgc aactcactag ctgttcagca ggcacttgac gtctatgaag aactgaaaga
     8041 aaaagtcaga gaagacgagc atgaatacgg accagctctt tttgaattgc aaaaacagat
     8101 caaagtgatc gaaaaagaat ttacgcagtt tgtgacttta aacacttctg gagaccctgt
     8161 tgaagcccgc gaggttttgg ataaagcaga aaaacatacg tatgaagtgg aagctctgat
     8221 gaaaaaaatt ccaccgctgt atgaggagct ccataccact ttccctgaac aacttgaaga
     8281 aatcagtgat acttacgaga aattgatgga agaacaatat gtattcccag aagaagatct
     8341 tgctgaagat atcgcaaaag taagtcgaag aattgaaaat tcattagcca atcttgaaaa
     8401 aacagaagtt gaaacggtcg aatttgaaaa ccgtgaaaca gctgatttga ttgattcgtt
     8461 atatgatatc ttagaacggg aaatggaagc tcagagatat gtaaaaacta accaatcaac
     8521 gattgcagag tatatcaaac atacaacaaa gaataaccgt caattattga ttgagctgga
     8581 tcacacatct caaagctata cattgaacca caatgaaatt ggccgtgtac gaggtttcca
     8641 aaccgaagtg gaagaaatgg aacgtcaaaa tgaacagatg attccacaga tccgtcaaca
     8701 cgaaattcct tattcagaag tgcgcacgtt ctataaaaca gtcttcaaag tcttagaaga
     8761 tatcgaaaag caacaagtag agatcgacga ctcattacat gaattgagaa aaggcgaaaa
     8821 agaagcgcaa gaaaagatcg atacattcga attcaaattg cgcagtttga aacgttttgt
     8881 agaaaaacaa cgtttgcctg gcttgccgaa tgattaccta gaattctttt ttgttgctac
     8941 tgaccgtatt gaagaactaa gtgttgtctt gaataaaatt cgagtaaaca tggaagaggt
     9001 caatcgttta gttgctctat gtgaagaaga tctagaatta ttagataaga agacacatga
     9061 tttagtagat gcagcagcat taacggagca aatgctccaa tatgcaaatc gttatcgtca
     9121 tacacacgaa gaagtgagag aagcaattga taaaagctac tatttattca ataaagaata
     9181 tcactatcaa gaagcattag acgaaatcgg tacagcatta gagcgagtag aacctggtgc
     9241 tttcaaacgc atcgaagatt tttattttaa tcatccagac ttagtataaa gcaaaaaagt
     9301 tagtaaacca gcaagagcaa gacggattat tgtcttgttc ttgtcttttt ttgtatattt
     9361 gaaaattgaa acaagtgaaa atttcacctg ctcttgaaag caccttggac aaccgttata
     9421 atagaaaaga atttcaaaaa agaggggttt cttatgatat attttgataa cagtgcaaca
     9481 accccaatct ttccgcaaag cttagatgca tatgtaaaaa ccagtcagcg gattattggg
     9541 aatccatcaa gcttgcatga tttaggcaat caagctaacc ggttgttgca gcaagcaaga
     9601 aagcagatcg ctgatttgat ccatgtagaa ccagaagaaa tctattttac ttcaggcgga
     9661 acagaaggag ataactgggt attaaaagga acgatgatcg aaaaaagaga atatgggaat
     9721 catatgatca tttcaggagt cgaacatccg gccgtcagcg agacagcaga acaattaaaa
     9781 gaattaggaa tcgaagtaag tatcgcccca gtggataaac gcggatttgt acgtgtcgac
     9841 gaattgaaag aattaataag aaaagagaca gtattagtct ctgttatggc tgtgaataat
     9901 gaagtaggat cgattcagcc catccaggaa atcagtgatc ttttggatga ttttcctaaa
     9961 attcatttcc atgtagatgc tgttcaggcg attggaaaag taccattctc gcaatggttg
    10021 acagaaagag ttgattttgc aacattttca gctcataaat tccatggccc acggggaact
    10081 ggtttcattt attggaaaaa gggtcgtcgt ttagcaccat tactgacagg tggagggcaa
    10141 gaaagaaatc agcgaagtgg gacagaaaat gttccaggta ttgtggctat ggttaaagct
    10201 ttacgtttat cattagagat aaaggaacaa aaacctgagc agacacaacg cttaaaagta
    10261 gctctaatca atgcgttgaa gacgtatgag aaagtgacga ttttttcaga aggaactgac
    10321 tatgcaccgc atattttatg ttttgctcta aaaggaattc gcggcgaagt tctcgtccat
    10381 gccttagaag aaaaacaaat atttgtttct actactagtg cctgctcctc acgtaaacat
    10441 atggcaagca gtacattgca cgcaatgcat gtaccaaatg atctggctac atctgctgtt
    10501 cgaatcagct tagatgaaaa caattcgctt gcagaagtcg agcaatttat gattattttc
    10561 aagcagcttt ataagaaatt ttctgcaatc aattaaaaga ggagtgttct tgtgaaatac
    10621 agtgaaatta tggtccgtta tggggaactt tcgacaaaag gaaagaatcg aaaaagcttt
    10681 atcatgcaac tagcacaaaa tgtcagacaa gctttgaaag actttccaga aatcaaaatc
    10741 catgctgatc gggaccggat gcatctttta ttgaatggcg cagacgggca gctagttatt
    10801 ccaaaactag caaaaatatt tgggatccaa aatttctctc caagtattcg tgtagaaaaa
    10861 gatgtcgaag ttttgaaaca agctgttcaa gacatcatga aagaaattta tactgggaaa
    10921 gaaacattta aaattatcgc taaaagaagc gatcaccaat ttgaattgac aagtaatgaa
    10981 ttgaatcaaa cattaggtaa tgctgttttt gatattttcc cgcatatcca agttcaaatg
    11041 cgtcaaccag atattccatt acgtgtagag attcggcgtg atggcgctta tctatcgtat
    11101 gaaacgatca agggagctgg aggattgccc gtaggaacaa gcggaaaagg aatgcttatg
    11161 ctttctgggg ggattgattc tcctgtagca gggtactttg ccatgaagcg gggagtggaa
    11221 attgaagctg ttcattttgc tagtccgccg tatacaagtg aacaagcact gcaaaaagca
    11281 aaagatctaa cagccaaact agcaccttat gtgggaacga tccattttat cgaagtgcca
    11341 tttaccgaga ttcaagaaga aatcaaaaag tcagtgccac aaggatattg gatgacaatt
    11401 actcgtcgaa tgatgttgcg tttgaccgat gaaattcgcc gtattcgtca tggtttagtc
    11461 attttgaatg gtgaatcatt aggtcaagtg gcttcacaaa ctttgcaaag tatggtggct
    11521 atcaatgaag taacgaatac gccaatcatt cggcctgtag cgacaatgga taaacttgaa
    11581 atcattgaag tagcagaaca gatcgataca tttaatcttt ctatccagcc ttttgaagat
    11641 tgctgtacga tttttgctcc tccacagcca aaaacacgcc ctcaactgga aaaggtccat
    11701 caatatgaag agcgtttagc aatagatgaa atgatccaac gagcactagc tggcttgaag
    11761 atggaagaga tacaagcaga atcgtctaat gaaaaaactg aagaattttc agaattgcta
    11821 taagaggtta tgaaaatagt gttttgacca gagtattaga gaaacaaaac gaaaaaatag
    11881 ctccatgtat tttaccgttt ttgaactaat gtcgaagatt agctgattga ataccattta
    11941 tcaagaagtt atggaaaagc cggttctttt ttactaactg aaaaataaaa ttttatttag
    12001 agatcaagct acagttgata aatgatataa aaaagagaat ttcccatgaa atagcgaggt
    12061 tgtgacagaa gtgggcagct tcaagaaata agaaggaatt tacgaaaatt gcttttcaaa
    12121 tttttgtgaa atttcggctt atttttcgaa gaagttactt ctggaacacc gtgtatcaga
    12181 ggttgcgaaa aagctgccct gcatcaagta ataagaacag ccaaacaaaa atagttcctc
    12241 atattttacg tttggttgag cttattaccg cagatgcaag cttttgaaca ccgttttatt
    12301 tgtctcacac ccttttcctt cctacttgta accttgctcc cgtgttagaa acatgttaca
    12361 ctaaatatgt gaaattatta acaaggagcg tcgttatgcg agaaaaaaca gatacactgc
    12421 caaaagcaac tgcgaaaaga ttacctttat atttacgcta cttgaagatg ctggatgact
    12481 caggtataag tagaatcaaa tcaaatgagt tcagcgaaat cacccaaatt ccttctgcaa
    12541 cgatccgcag agacttctcg caattaggcg agctaggcag aagcggatat ggctatgatg
    12601 tcccttttct tatcgatgta ttcaataata tccttaatac taaagaagaa aaacgaatcg
    12661 cattagtagg atatggaaat cttggcaaag cattgaaaca caacaatttt agaagaaatg
    12721 aaaatctaaa tatcgtgtgc gtctttgata atgatccagc actgatcaat cgagtaattg
    12781 atggagaaat gatctatccg attgatcgtt tcgcggagat agccaaagca aaaaatgtga
    12841 cagtagcaat ctctacggta ccaagtaaat attcacaatc tgctattgat gaaattgtca
    12901 aaggaaatgt aaccgctata cttaattttg cgcctgacag agtaactgtc ccagcttatg
    12961 tcaatgttca atacattgat ttgacaaccg agttgcagac gcttatttac tttgatgaga
    13021 attactcaga agttttttct taggaaaatt tgagtaggct tattgatctt gcgagaactc
    13081 gtcgtaattc tttcaaaaat tttttagtac taaatgaagt ggttttttca cgaccacttg
    13141 ttgactaaaa aaaaaaacca ttgtagaatg aagcataacg ctgaacaaga ggagtaactg
    13201 gcacattcat tcttagagag agaactatct gctgaaaggt tctcaatgac aaccagtgaa
    13261 ggtagcttgg gagtttctgt cttgaatgga gtagagatag acgagtcgtg atcgttaact
    13321 cacttgagag gcaataatga ttgattattg caatttaggt ggtaccgcgt aaatcatacg
    13381 tcctagaata cgaaagtatc ttaggacgtt ttttagttta aaggaggaaa acagcatgac
    13441 ggaagaaaat aacctatcaa caaaatataa tccgcaagaa gttgaagctg gacgttatca
    13501 gcattggtta gaacaagatt tgtttaaacc gagcggagat aaaaaagcaa aaccttattc
    13561 aatcgtaatc ccgcccccaa atgttactgg aaaacttcat ttagggcatg cttgggatac
    13621 gaccttgcaa gatatgctga ttcgtcaaaa gagaatgcaa ggatatgata ctttatggct
    13681 gcctggtatg gaccatgcag gaatcgcgac acaagcaaaa gtagaagcga agcttagaga
    13741 gcaagggatt tctcgttatg atctaggtcg tgaaaagttc atcgatcaag tgtgggaatg
    13801 gaaagaagag tatgcgagcc acatccgcga acagtgggct aaaatgggct tatctttaga
    13861 ttacagtagg gaacgtttta cattagatga tggattatct gaagcagtac gtaaagtttt
    13921 tgttacctta tacgaaaaag gtttgattta tcgtggtgaa tatatcatca actgggatcc
    13981 tcaagcacga acagctctat ctgatatcga agttattcat aaagatatcg aaggcgcctt
    14041 ttatcatatg agctatgaac tagcagatgg atcaggcgta gtagaaattg cgacaacccg
    14101 tccagaaacg atgttgggag atacggcgat tgctgttcat ccagaagacg agcgttatca
    14161 agcgctcatc ggcaaaaaag tgattctacc tttagtcaat aaacaaatcc caatcattgc
    14221 agatgaatat gtagatatgg aattcgggac aggtgtagta aaaatcactc cagcacatga
    14281 tccaaacgac tttgaggtag gtaatcgtca tgatcttcca cgcgtaaatg ttatggatga
    14341 tgatggtacg atgaatgaac tagcaggaaa atatgctgga atggaacgtt ttgctgctcg
    14401 taaagcaatc gtgcaagatc tgaaagaaat cggtcgattg attaaaatcg atacgatgat
    14461 ccacagtgtg ggtcattccg agcggacagg tgtcgttgtt gaacctcggc tgtctactca
    14521 atggtttgta aaaatggcgc cgttagcgaa aaaagccatt gataaccaag aaacagatca
    14581 agcagtggaa ttcttccctc caagattcaa tcaaacgttt ttacgttgga tggaaaatgt
    14641 ccatgattgg gtaatctcac gacaattatg gtggggacat caaattcctg catggtatca
    14701 caaagaaaca ggtgaaatgt atgtagggat ggaagcacca gcggatagtg aaaactgggt
    14761 acaagatcct gatgttttag acacttggtt tagttcagct ttgtggcctt tctcaacaat
    14821 gggctggcca gatacggaaa gcgaagatta taagcgatac ttccctacta gcactttagt
    14881 aaccggttat gacatcattt tcttctgggt aagcagaatg attttccaaa gcttggaatt
    14941 tactggcgaa cgtccatttg agaatgtctt gattcatgga ttgattcgtg acgaacaagg
    15001 gcggaagatg agtaaatcat taggtaatgg aatcgatccg atggaagtaa tcgaaaagta
    15061 tggagcagat gctctccgct ggttcttatc gaatggttct gcaccaggac aagatgtccg
    15121 cttcagctat gaaaaaatgg atgcttcttg gaactttatc aacaaaatct ggaatgcttc
    15181 acgtttcgtt atcatgaata tcgaaggaat gaccgtagaa gagatcgatt tatctggaga
    15241 aaaatcagtg gctgaccggt ggatccttac tcgtttgaat gaaacgatcg aacgagtaac
    15301 tgagctattt gatcgttttg aatttggtga agcaggtcga caactgtata actttatctg
    15361 ggatgatttt tgtgactggt acatcgaaat gagtaaagaa gtactttatg gagatgatgc
    15421 tgtttcaaaa caaaccaccc gtagcatctt agtccataca cttgatcaga tcctacgttt
    15481 attgcatcca atcatgccat tcgttacaga agaaatatgg gaacatattc ctcatcaggg
    15541 aaattctcta gtagtggcag aatatcctgt tgtacgtcca gagtttgatg atgaaacagc
    15601 ttctaaaggg atggaagtat tgaaagaatt gattcgagcc gttcgaaata ttcgttcaga
    15661 agtgaataca ccattgtcta aaccaattac gttgctaatt aaaacaaacg atgctaaaat
    15721 cgatcaattt ttagttgaaa atacaagcta tatcgaacgc ttctgtaatc ccgaagagtt
    15781 gacgatatca agtgagatca ctgcgccaga tctagcgatg tcagctgttc tgacaggtgc
    15841 agaaatcttc ttgccgttag caggattgat caatattgaa gaagaaatca aacgattaga
    15901 aaaagaactg gaaaagtgga caagcgaagt aaaacgtgtc caaggaaaac tttctaatga
    15961 acgttttgtt tctaacgcgc cggaagaagt agtagaggca gagcgtgcaa aagaaaaaga
    16021 ttatttagag aagcaaacgg ctgtcaaaga acgaatcgaa agtttgcgta ctattcaata
    16081 agaatagaaa aagagagtgt gaaatcagct agctattact aaaagctagc tgattgaaca
    16141 tcgttacagg aaagagtttg agcctcactc ttagcttcga ttcataagga gatgtgacat
    16201 aaattttgtc gcatctcttt tttagtctac tcttattatg taggagaagg agggaggtgg
    16261 atcatgtatc aagagtcaat aaagtagttg ataaaatcgt tcctctctct gtttcttttc
    16321 tctttgtcat acttttattt ttcttatgtg ttctatttgt tataataaaa gagaaatggg
    16381 ggaattgttg atgacgattg aagaagcaat agaatggatc catagtcgat taccatttgg
    16441 ttcacgtcct ggccttgacc gagtcgaagc tttattagaa gtggtagggc atccagagag
    16501 aaaagtaaaa acgatccata tcgctggaac aaacggaaaa ggttctactg tagcttattt
    16561 gagaagccta ttagaagagg ctgggctgac agtaggtaca tttacttcac cttatatcga
    16621 aacgttcaat gaacggatcg caatcaatgg caaaagcatt ccagacaatg atttgatcca
    16681 gcttgtaaaa aaatatcagc cactgatcaa acaacttgat caatttgaag cagtagctgg
    16741 tattactgaa ttcgagacat taacagcaat ggcatttgat tattttttga tgaagaaagt
    16801 ggacgtagcg attatcgaag ttggcttagg cggcttattg gattctacca atgtagctgt
    16861 accaatgctg acgggaataa caacgattgg acttgatcat accgaaatac ttggagatac
    16921 aattgaagaa atcgctgcac aaaaagctgg aatcatcaaa caaggcgttc cagtagtaac
    16981 aggaaatatt gccccagaag cttttactgt catccaacaa acagctaaag caaaaaatgc
    17041 accgctttat gtatacgggg aaaattataa aataaactat ctgcatcctg atgagatgtg
    17101 gggagaagta tttgaatttt ttaatgaaat aggaaagatc cctcaattaa ccactccgct
    17161 tttagggcaa catcaagctg aaaatgcagg agtagccatc gaattgtatt ttgtttactg
    17221 tcaattggaa aagctgcctt tccgagaaaa agatgttttg aagggattga agaaatctcg
    17281 atggccagga agaatggagc gtttgagtaa cgagccatta gttgttttag atggtgccca
    17341 taatacgcat gcaatgaacc ggcttgttga gaatttgaaa aaagaattca aaggatatca
    17401 aatcaacatt ttgttttccg ccttacgaac taaaaatgtt agagaaatgc tagaacgatt
    17461 gcagcaagta ccaaatgtcc atatttattt gacgaccttt gaacatccaa aagccatcga
    17521 attaagtgaa gtatcagatt tagcaagtga gagagtatca atcgtttcat tgtggcaatt
    17581 cggattagca gatatattgg aaaagatgac aaatgaagac gtattagttg tgaccggttc
    17641 actttatttc atttcagaag ttcgccattt attaatacaa ttaggaggag atcatgaagt
    17701 ataatgcagt gatttttgac atggatggtt tgctgttcga cacagagtta gtgtattacg
    17761 aagccacaca agtagtagca gacaagatgg gttttcctta tgataaagac ctgtatttaa
    17821 aattcttagg tgtttcagat gaagaagtat gggcgaatta tcatatgatt ttctcggaat
    17881 ttggcaaaac aagtgtacaa agattcatag atgattcata ccaggaaacg cttgaacgtt
    17941 tttcgcaagg agcggtacaa atgaagcccg gtgtgttgga actcctctct tttttagaag
    18001 aacatcagat tcccaaagtt gtcgcttcca gtaaccaacg agcagtcatt gaacttttat
    18061 tgaagaagaa caatctgttt gaacgatttg agacgattgt ttctgcagaa aatgttcaac
    18121 gagcaaaacc agacccagaa attttcttgt tagctaatca gaagctaggt acagcgaaga
    18181 aagaaacatt gattttagaa gattcacaaa atggtatttt agcagcttct gcggctgaga
    18241 tcccggtagt catggtacca gatctgcttc caccatccca agaattgatc aaaaaaacag
    18301 ctggggttgt ttcttcttta catgaaatcc ctgcattgtt aaaataaaaa tccatctctt
    18361 ttcgtatctt attttagata agatagaaag gagatgtttt tttgggaaaa cgattgatca
    18421 aagaagtacc tactagctct ttaccaaggg aacgtatgga aatttatggc gcggaagctt
    18481 tatcggatca ggagcttttg gcaatcttac tgcgtaccgg tcaacaccct tatagtgtga
    18541 tgtcgattgc tggaaatctg ttaaaaacgt ttggaggact ggcctcttta cgacaggcta
    18601 ctttgcatga gttagaagag attcgaggga taggacgcgt gaaagcaatc gaaatcaaag
    18661 ccttgatcga attaggtcga cgaattcaga cggatcatga aagagcggct ccaccggttc
    18721 gtaccagcta cgaattggcc cagcaattga ttctggaaat gaaagatcac aaacaagaac
    18781 atttggtttg tatttatttg gacacgaaga atcaagtgat cttaaaaaaa acagtgttca
    18841 tcggttcgct gaatcagtca gtcgctcatc ctagagaaat tttccattat gctgtacgtt
    18901 attgtgcagc aaggatcgtt ttagcgcata atcatccttc tggtaatgtt attccatcgc
    18961 agcaggatat gaattttacc aaaaggatac aaaagtgtgg agaaatgatg gggatcactg
    19021 tactggacca cttgatcatc ggacgcaaac gatattttag tttgagagaa gaaggaatga
    19081 tggaagagaa gtaagttgct ttcttgcaaa aaaaatgaag caagtgtaca attatattgt
    19141 aattttgttt gggaatagaa gttgaaacat ctgttgcacc tctatcgtac acgagcaatg
    19201 ttacaattta aattagtgct tttggcacga ggaggatatt attatggaaa acggaacagt
    19261 aaaatggttc aacgctgaaa aaggatttgg atttatctca cgtgaagatg gaagcgacgt
    19321 attcgttcac ttctcagcta tccaaggtga cggattcaaa acattagaag aaggtcaagc
    19381 agtgactttc gacgttgaag aatcagaccg cggcccacaa gctgcaaacg ttgtaaaagc
    19441 ttaattttat ctgtaaatca aattgatggt agacatcaat ttttacgaga gaacaaagcg
    19501 agtaacaaaa atacctgcca caagagacaa tttctcttgt ggcaggtatt tttttgtatg
    19561 aaaaagtaaa taaatttaag aggctatgaa agagccacct tgtatcaagg aataagaaca
    19621 aacaaaaatg gcttctcatg tttttcattt gttttctctt atattcagga caaggtgctg
    19681 atttcataac ctcttattta ttcttcatct ggtgtcatta ccattggcaa aatcattgga
    19741 tgtctttctg tacgttcgaa taagaaaggc tgaagcgcgc cagtcatcgc ttctttcaat
    19801 ttatattctg aacagtcagg tccattcaaa cattctctta aagcgtggaa taagattcgc
    19861 tgagcttcat tgatcatttc tcctgattct cgcatgtaga caaatccacg agagagaata
    19921 tctggaccag ccaagatttc ttttttcttg atatccactg tcgcgacagc taatacaaga
    19981 ccttcttctg aaagcaggtg acggtcacgt aaaacgacat taccaatatc accgatcccg
    20041 ctaccatcga tatacacatc tccagccaca aaatgcccag caggacgcgc agaatcgcta
    20101 gttaacgcta aaacatcgcc attttccatg atgaagcagt tttctgcagg aacacctaca
    20161 tcttgtgcta gagaagcatg tactttcaac atgcggaatt ctccgtggac aggaataaaa
    20221 tattttggct tcatcaaacg aagcattaat ttttgttctt cttgtccacc gtgaccggaa
    20281 gtatggatgt tattgatttt tccgtgaatc acttctgcac cagcttcaga cagcaaattg
    20341 atcaaatgat tgacacttgt tgtattacca ggaataggtg aacttgaaaa gatcactgta
    20401 tcgtctggct ggatttggat ttgacggtga gtaccattcg cgatgcggct caacgcggcc
    20461 atcgcttctc cttgagaacc tgtacatagg atcatcgttt cattggcagg caagcgattg
    20521 atttcgtgtg catctacaaa tgtgccgtct ggaactttga tatatcctaa acgttgaccg
    20581 ttgacgatgg cattttccat gcttcgtccg aaaacagcga ttttacgacc agttgccaca
    20641 gcggcatctg ctgcttgctg caaacggaag atgttagaag caaagctggc aaaaatgata
    20701 cgtccttcga tttttgaaaa gatcttcaaa atagaatgcc caatcgtttt ttctgattta
    20761 gtaaatgttg gaatctcagc atttgtacta tcagataaaa ggcacaagac tccttcttcc
    20821 ccgatacgag ccattttatg caagtttgct ggttcgccaa caggagtgaa atcgaatttg
    20881 aagtctccag tcgctacgat atttccagaa ggtgttttca ccacgatccc taatgcatct
    20941 gggatactat gggtcgttct gaaaaagctg acagaagtct ttctaaaacg gatgatcgta
    21001 tcttcattga tctcatggag ctctgcatct cgaagcaagc catgctcatc taatttgttt
    21061 gtgatcaacg ctaatgcgag aggaccagca tagataggaa tatttgcttg tttcagcaag
    21121 tagggtattc cgccgatgtg gtcttcgtgc ccgtgagtaa tcaccaaggc ttttactttg
    21181 tgtaagtttt gtatgatgta gctgtagtcg ggaatgacat agtcaattcc aagtaaatcg
    21241 tcttccggga atttgatccc ggcatcaatc aaaatgattt catcttggaa ttgtacccca
    21301 tacgtatttt tcccgatttc acctaatcca ccaatagcaa agacgcctgt ctcgttattt
    21361 ttgatggaaa gtttcatatt aaaactccac taatgagaaa tcagcatttt ctttttcgta
    21421 ctctagatga cttccttcta gaagttgaac gaattcaata ttgtatgggg tattttcttc
    21481 cacacgttgg cgagcgtcta catcgctttt tgcctcaatg taaagagatt ttgtttcttc
    21541 ccgtttaggg ttgcgtactt ttgtttcttg ataataaact ttatagatca ttgttttgtc
    21601 tcctttatct gcgtaaagca gtgatttagc tagttgattt ttttagacaa cacaaaacga
    21661 ggggacaagc cacctggttt ttcatatgct ttgactagaa tactggattc gagtcaaaga
    21721 gacaagcctc gtttttgctt atctgttcgg atattttttc aaccgtacct tctgtataaa
    21781 aaatatacaa caattaattg ttattctagc ataaaacagc aaataagtat agaaatcaac
    21841 tagattgaaa gaaaaaatca atgtttatca tcccgctata atcataatga cttttttatg
    21901 agagaagtgt tctattaata ggctcgttgt gctatcattt ttagtaatga aaatgtaacg
    21961 aaagattaaa aggagatgag aaagtgaaac taatgtggca ttataccatg cgttataaga
    22021 aattcttgtt tttcaatttc atatgcgtat ttggttttat tttgattgaa ttaggacttc
    22081 ctacgatttt agcacgtatg atcgatgtag gaatccgcaa tgatgatttt gattatgtga
    22141 agcaacaagg gatatttatg atcgttatta ctgtaatcgg tattattttg aatatcttgt
    22201 taggttattt tggttcgagg attacgacta atatcgtagc agatattcga gatgatttgt
    22261 tcgaaaagat ccaaagttat tcgcatcagg aatacgaaaa tctaggcgta tcttcattga
    22321 tcactcgtac aacaaacgat gcttatcaga tcatgttgtt cctgcaaaat attttacgta
    22381 tcggttttat ggcaccaatg atgttcattg tcagtttgta catggtcatg cgtacaagtg
    22441 tgacactcag tttgtatgta gtaggtgcat tacctttact attattggca gtcgtagcga
    22501 ttgctaaggt gtctgaaccg ttatctaaaa agcaacaaaa aaacttagat aaaatcaaca
    22561 gtatcttgcg ggaaaatctt tcaggattgc gtgtgattcg tgcattcgtc aatgaaaagt
    22621 ttgaagaaaa acgttttgct gtagtcaatg agaattatgc ttctagttca aaaagcttat
    22681 tccgtttgat ggctgttgca caaccgggtt tttatttctt atttaatatc gtaatggtat
    22741 tgatcatctg gagcggggca gtgcaaatcg atgcaggcga gcttcgtgta ggagatttga
    22801 ttgcgtttat cgagtatata ttccatgcct tgttctcatt catgttattt gctagtgtgt
    22861 tcatgatgta tccaagagca gctgtttcag ctggacgtat ccaagaagcc ctagatgcca
    22921 aaccttcgat tgtagaagat ccaaatggta tatctgatac aaaaactaaa gggtatatcg
    22981 aatttcaaaa tgtaacattt gcttatccag gccattcgca agagccagtg atacgaaatg
    23041 tcagttttac agcctctcca ggagagaccg ttgcttttat tggaagtacc ggtagcggaa
    23101 aatctacgtt gatccaattg atccctcgct tttatgatgt gagtgaagga aagatcttga
    23161 tcgatggagt agacgtgaga gattatcggc taagcaagtt gcgagataag attgggttta
    23221 ttccgcaaaa agcgctgcta tttactggaa cgattgcaga taatttgcga tacgggaaag
    23281 aagatgctac gcaagaagaa atggaacgtg cagctgagat tgctcaagct tcagaattca
    23341 tttctcgaaa accagatgga tttaatgaac atttatcaga aggtggttcc aatttttcag
    23401 gtggacaaaa acaacgattg gcaatagcca gagccatcat acgccgtccg gaaatctata
    23461 tttttgatga cagcttttct gcattagatt atcaaacgga tgcgaagtta cgtgctcgtc
    23521 tgaaaaaaga aacgacagaa tctactgtat tgatcgtagc acaacgtgtg ggaacgatca
    23581 tgcatgcaga taagatcatc gtattaaatg aaggagaagt cgtcggtatg gggacgcatc
    23641 gggagttgtt ggaaaaatgc ccgatttatt atgatattgc cgcttctcaa ttatcaaagg
    23701 aggaattagc atgaaaaaaa ccttttcttc cttaaaacgt ttagctcgat atatcagacc
    23761 gtatcgtgag acttttcttt tagtgatcct atttacagtt ctgacagtgg ctttcaacgt
    23821 ggctttgcca tatgttacag gacttcctac tacagaaatc agccgtaata ttgccaatgg
    23881 cgaatcaatc aatttttctt atatattcaa atgtctcatt tggatcacag ttgttggaat
    23941 agggtattgt atttcgcaat tactttctgg tgttttgatg acaaatgtcg ttcaaagtgc
    24001 catgcatgat ttgagaagag acatagaaga aaaaatcaat cgtcttccgg tttcatattt
    24061 cgataaaaac cagcaaggaa atattttgtc tcgtgtgacg aatgatgtag atgcagtcag
    24121 cggtgcttta caacaagctt ttattggtat cgtaaatgcg atattgggaa ttacgttggc
    24181 tgcagcaatg atgttttata tccagccgat gatggcgctg atctctatga tcatgattcc
    24241 aacatcgatc tggatctcaa aacgagtgat caatgcttcg cagaaatatt ttcaaagcat
    24301 gcagaattct cttggtgagc taaacggcta cgtccaagaa aatatgacag gttttagtgt
    24361 attgaaagta tatggacgcg aaaaagaaac attggaagga ttcaaaaaag ttaatcacag
    24421 cttgaaatac tttgggtttc gtgcagcatt catttctggc ttgatgatgc ctctagttca
    24481 attaactgcc tatgctactt atattggtat ggctgttcta ggaagctttt atgttattac
    24541 tggggcgatc gttgtcggtc aactacaagc attcatccaa tatatttggc aaatcagtca
    24601 gccaatgggg aacgtgacac aattgtcttc agttttgcaa agtgcatcag cggcaacgaa
    24661 acgtgtattc gagattttag atgagccaga agaaaaagaa aacaaagtag atgcttcact
    24721 gccagaaacg attttaggag atgtgacatt cgatcatgtc gattttgcat atgatccgaa
    24781 gaaaccatta atccaagatt tgaattttga agtgaaagct ggtcaaaccg tagctgtggt
    24841 cggtccgacc ggtgccggca agacgacatt gatcaatcta ttgatgcgtt tttatgacgt
    24901 agacaaagga gcaataagga ttgatggaat cgacaccaaa tcaatgagtc gcagtgatgt
    24961 gcgttcgcta tttggtatgg tcttgcaaga tgcatggctt tatcaaggaa cgattgcaga
    25021 taatatccgc ttcggaaagc ttgatgcgac agattatgaa gtagttgatg ctgcgaaaac
    25081 agcaaacgta gatcatttta tccgaacgat gccagatgga tatgatatgg ccatcaattc
    25141 tgagggagac aatgtgtctt taggacaaaa acagttgctg acgattgccc gagcagtggt
    25201 ctccgatcct aaaatcttga ttttagatga agcaacaagt tcagtagaca cccgtttaga
    25261 agcgttgatt caaaaagcaa tggatcgcgt gatggaggga cggacaagtt tcgtcatcgc
    25321 tcaccgttta tcgacaatcc gtgatgcaga tctgattcta gtgatggatc aaggtcagat
    25381 cattgaaaaa ggaacgcatg agagtttatt ggcacaaggt ggattttatg aaaaactgta
    25441 taacagccaa tttgctgagg aagcagaata agtcatataa gaataaaaca gtttaaaact
    25501 tattttttgt tctctattct tgataatggt aaagtaaagt tatcaagaaa agtgaggaca
    25561 cggagatgga acagttttta aatgaaaaaa ttactgaagc caaaagagaa gttgatcgtt
    25621 taacgcacgt ctgtcagacg aagccttttg attcagctga tttttttgaa aatgagtttc
    25681 aaatcgaacg cttggcagca caaatagaag tgtacgaatt aattttaaaa aaagtaatag
    25741 aagaaaatat agatgtacaa taaaaacagg taaaacgtca gttaccagat actgtaaata
    25801 gacatctggc ctgagcaggt tttacctgtt ttttttctta tgaaataaat atatgctatg
    25861 atacctttat tcaataggat tagtttctac aaaaaatgaa aggagaaaaa taaatatgga
    25921 acggtttata gcatcaaatg ccacagtgat tggtgatgtg acattgtcag aagatgtgac
    25981 gatctggtat caagctgttt tacgcgggga cagtaattgg ataaaaatag gacaaagaac
    26041 gaatatccaa gatggtacaa tcatccatgt cgatcatgat gcacctgtag atattgcgga
    26101 gaatgtgacg gtaggacatc agtgcatgct acatggctgt acaatcgaaa aaggggcgct
    26161 gatcgggatg gggaccacga tattgaatca tgcggttatt ggtgagaata gtttgattgg
    26221 tgctggatca ttagtaacag aaggaaaagt tattcctcct aatgtcttgg cttttggtcg
    26281 cccagctaaa gtgatccgtc ctttgacaaa agaagaaata caaaaaaaca aagaaaacat
    26341 ccagcattat gtcgagatag gtcggatgca tgcgcaagga aaattcaagg agcaaagata
    26401 ggcagtagca tccataaaat aaaaaaggat ggtcagtttg agttgaccat ccttttttat
    26461 ttggtttaga taagagagct taaaaaagct tcctttgaaa cagattaatt taatgaagaa
    26521 ctgttttcca tgacttcatc gatcaatcca tatgcttttg cttgttcagc tgtcatatag
    26581 ttgtcacgat ctgtatcttt ttcaatcact tcaagcggtt gtccagtgcg ttcagctaaa
    26641 attttgttta agcgttcgcg tgtttgcaaa atatggcgtg ccgcaatttc gatttcagtt
    26701 gcttgccctt gagcgccgcc aagaggttga tggatcatga tctcagcatt tggtaaagca
    26761 aatcgtttac cttttgtacc agctgtcagc aagaagcttc ccattgaagc agccataccc
    26821 ataacaattg tttggacatc tgctttgaca aagttcattg tgtcgtaaat agccatacct
    26881 gctgtaactg aaccaccagg agaattgata taaagataga tatctttttc agaatcttga
    26941 gcgtctaaga aaagcaattg ggcgatgatc gaattagcaa gatcatctgt tacttggccg
    27001 cttaacatga tgatacggtc tttcaataaa cgtgagtaga tatcgtaagc tctttcacct
    27061 cgtgaagatt gttcaatgac tgtaggaatt aaattcataa tagagttcct ccttgatttc
    27121 gtttagaaat agtgtaccat aatttagttt ctaataccta aaatgtagta tacatttttg
    27181 gtcaaaaaag gtcaaataaa aaacttaggc aaattagtcg cataaacccg ctttatggta
    27241 tgataagcag agaaacaaaa caaggaggaa caacagattg atagttggta ttactggcct
    27301 tatcggagtg ctgacaggtg ctgtagttgt ctatatcggc atgatactgc aaatgcgtca
    27361 cttggaaaat aaagaacagc gtagacgtga attggaattg aaagtcaaag aaatcgagac
    27421 gctgaatcaa ttaaataaaa agatcaacga gatcttgcaa aaacggacaa cgctgatgga
    27481 agaatatgtc agctttgatg catttgatga ttgttatatc acgattgacg attttgcgta
    27541 tctccaatca ttttcagcgc aaaatagttt ttatctgcca aattatattt tagacgagct
    27601 atttaagaat atctcccatc gaaaagtgat tttatctcca gatgaaacaa tgaagattgg
    27661 tggatatgct tataaaggcg gacgcgtgat tttagagaat tttacggata gtctgactga
    27721 aatgatcaat gaaaaaaaag ctcagttgaa gactatgacg cgccagccga ttggtttctt
    27781 ctcgaaagat gatgtttgga gctgatattt tgaagcattg ccgttgcaca tgagagcgtg
    27841 gtaatgcttt ctttttttct taatgataca atagaactga acggagtgaa gaaagatgtt
    27901 acaaatctat gcccatcgcg gaagcagcgg cacccaccca gaaaatacgc ttcctgcatt
    27961 tgcagaagct gtacgagtag gtgcagatgg tatcgaacta gatgtccatc taagcaaaga
    28021 tggttatttg atcgttatgc acgacgaaga agtggaccgg acgactaacg gtaaagggct
    28081 gattcgagaa aaaacattgg aagaactcaa aaaattgaat gcagggggca aattcagcaa
    28141 agaatttcca gcagctaaag ttcctgaatt gagagaagtg ttaggactgc tcctccaaaa
    28201 aaattaccga gggatgctaa tgattgaaat taaaactgat cagtatgaat atcccggtat
    28261 cgaagaaaaa ttagccgaaa cattaaaaag tagagattgg ccttttcaac atgcatattg
    28321 cagctttcat ttggattctt tggaaaaaat cgcattactg gaaccggaga tacagctgga
    28381 cttattgatg agtacttctg ataaaaagat ccaactagca gcagaaaccc cttatataga
    28441 aggagtacat ccaaaaaata cttggttgtt cgaacatcca gtccaggcag ctgattttcc
    28501 aaaagcaatt cgtgcatgga cgattaacga tgaagaagaa atggccaaat gtcaagaact
    28561 caaaatagat ggaataataa ctgattttcc ggagaaagct cttcggtgga aacaatcaac
    28621 gaaaagtagg taaaatatgg aaaaagtatt agtgatcgtc ggtccgacag cagtcggtaa
    28681 aacagcgcta agtgtggaac tcgcacaact atttggagga gagatcatca gtggtgattc
    28741 attgcaaatc tataaaaatc tggatatcgg tacagcaaaa atcaaagaag aagagatgaa
    28801 taatgttccg catcatttga ttgatgtgat cgaacctact caacgttact cagccgctga
    28861 ttttcagcat tcaggtcgac aattgattac cgagattgcg aaccgagggc acctacctat
    28921 catagctggt ggtacgggtc tctatatcca atcccttcta tatgattatc agttaggagc
    28981 gacagaagaa gcgaatcctg agattagaaa aaagtatgaa acgttagctg aaacaattgg
    29041 ttcccaagca ttatggaatc agttgaaaga aaaagacccg gcagctgctg agaaaatcca
    29101 ctggaacaat caacgcaaag tgataagagc tctggaagtt ttagagacga caggacatag
    29161 tatcacggca cctaaagaag agccaaagca attgtatgat tacctcatga ttggattaga
    29221 tacgaagcgt agtattcttt atgaacgaat caatcaaaga gtcgatttga tgctagcaga
    29281 aggtttagta gcagaagcgc gtaaggtgta tgagcttgga gaagtccagg ccagtcaagg
    29341 tattggatat aaagaatttt tcccttattt tgaagggaaa gaaacattgg aagaagcaac
    29401 agaacaagtc aaactacatt cgagaagata cgcgaaacgt cagttgacgt ggtttcgtaa
    29461 ccgtttggat gcacagtggt ttgatcttat aagtgagcca aatcaaaaaa gtcagattga
    29521 gcaaacaatc aaaaaatggc tggaggcgga ataaaatgga agaaaaagtg atcatcgtag
    29581 gggtagaaac cgaagcaaac cagcgttact tttcagagtc aatggaagag ctagttcagc
    29641 tgacgaatac cgcatcagga gaagtcgtat tcacaattac acaaaagaga ccacaagtgg
    29701 atcggcaaac gattatcggt aaagggaaat tacaagaatt agttcaacaa gcggatgcgc
    29761 atgaagcgga tttgatcatc tttaatcatg agctaactcc gagacagagc caactgatta
    29821 ccgatgctgt tggtcttccg gtaattgatc gcgtgcagct tatcttagat atttttgcga
    29881 tgcgtgctcg ttcgaaagaa gggaagctgc aggttgaact tgctcagtta gaatacctgc
    29941 tgcctcgttt agtagggcaa gggaaaacat tatctcgtct tggcggtggg atcggaacaa
    30001 gagggccagg tgaaacaaag ttagaaacag accgccgaca tatacggaat aaaatttttg
    30061 ctgttaagaa agaattgaaa gaagtagaag ctcatcgaga gcgcaatcgc caaaaaagaa
    30121 aaaatagcga gatttttcag attggactta ttggctacac gaatgccggg aagtcaacta
    30181 tcttgaatct attgacacaa gcggatactt attcgaaaga tcaattgttt gcaacgttag
    30241 atccattgac taagagatgg cgttttgctg aaggatttga gattactgta acggataccg
    30301 tcgggttcat ccaagacctg cctacgcaac tgatcgatgc tttccattct acattagaag
    30361 aaagtcaaaa tatggatctt ttgctacatg tagtcgatgc tagttctcca gatcgtattt
    30421 tacaggagca gactgtctta aaattgatgg atgaactgaa tatgaaagaa atgccgatac
    30481 tgactgttta caataaggca gaccagatcg acccagcgat gttcacgcct acgctattcc
    30541 caaatgtatt gatttctact cagacgaaag aaggtaagat ggcgttgatc gaagcaatca
    30601 aacgtcagct gatggaacta atgacccctt atacactttc tgtgccaagc aacgaaggac
    30661 agaaattaag cgagttgaga agacaaacaa tggttttgga cgaagcgtac atggaagaaa
    30721 caaacgaata tgaagttaaa gggtttgcaa aaaccaattc aaaatggtta agaaaaaacc
    30781 aataaaattt tattttttta ac
//
LOCUS       DADVXB010000017        30770 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.017, whole genome shotgun sequence.
ACCESSION   DADVXB010000017 DADVXB010000000
VERSION     DADVXB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.017"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(54..500)
                     /locus_tag="KB902_000591"
     CDS             complement(54..500)
                     /locus_tag="KB902_000591"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBB6807443.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRIRGITVATGRFGADMSVSLVNDGPVTIIIDSKNK"
     gene            complement(511..2724)
                     /locus_tag="KB902_000592"
     CDS             complement(511..2724)
                     /locus_tag="KB902_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBB6807444.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            complement(2957..3721)
                     /locus_tag="KB902_000593"
     CDS             complement(2957..3721)
                     /locus_tag="KB902_000593"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBB6807445.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            complement(3722..4669)
                     /gene="prmA"
                     /locus_tag="KB902_000594"
     CDS             complement(3722..4669)
                     /gene="prmA"
                     /locus_tag="KB902_000594"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBB6807446.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQIVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            complement(4682..5170)
                     /locus_tag="KB902_000595"
     CDS             complement(4682..5170)
                     /locus_tag="KB902_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBB6807447.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            complement(5136..5807)
                     /locus_tag="KB902_000596"
     CDS             complement(5136..5807)
                     /locus_tag="KB902_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBB6807448.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            5945..7231
                     /locus_tag="KB902_000597"
     CDS             5945..7231
                     /locus_tag="KB902_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBB6807449.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            7303..7497
                     /gene="ssrS"
                     /locus_tag="KB902_000598"
     ncRNA           7303..7497
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KB902_000598"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            7575..7859
                     /locus_tag="KB902_000599"
     CDS             7575..7859
                     /locus_tag="KB902_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807450.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            7932..8411
                     /locus_tag="KB902_000600"
     CDS             7932..8411
                     /locus_tag="KB902_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6807451.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            8634..8777
                     /locus_tag="KB902_000601"
     CDS             8634..8777
                     /locus_tag="KB902_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBB6807452.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            9355..10938
                     /locus_tag="KB902_000602"
     CDS             9355..10938
                     /locus_tag="KB902_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6807453.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNPYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDESTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(11375..12559)
                     /locus_tag="KB902_000603"
     CDS             complement(11375..12559)
                     /locus_tag="KB902_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBB6807454.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(12584..13591)
                     /locus_tag="KB902_000604"
     CDS             complement(12584..13591)
                     /locus_tag="KB902_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6807455.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(13763..14122)
                     /locus_tag="KB902_000605"
     CDS             complement(13763..14122)
                     /locus_tag="KB902_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807456.1"
                     /translation="MPYGQKPISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(14094..14465)
                     /locus_tag="KB902_000606"
     CDS             complement(14094..14465)
                     /locus_tag="KB902_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBB6807457.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKTDQ"
     gene            complement(14482..14784)
                     /locus_tag="KB902_000607"
     CDS             complement(14482..14784)
                     /locus_tag="KB902_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807458.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(14801..15271)
                     /locus_tag="KB902_000608"
     CDS             complement(14801..15271)
                     /locus_tag="KB902_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBB6807459.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(15246..15524)
                     /locus_tag="KB902_000609"
     CDS             complement(15246..15524)
                     /locus_tag="KB902_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBB6807460.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(15521..16570)
                     /locus_tag="KB902_000610"
     CDS             complement(15521..16570)
                     /locus_tag="KB902_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBB6807461.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(16527..17456)
                     /gene="tadA"
                     /locus_tag="KB902_000611"
     CDS             complement(16527..17456)
                     /gene="tadA"
                     /locus_tag="KB902_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6807462.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            17588..19342
                     /gene="ade"
                     /locus_tag="KB902_000612"
     CDS             17588..19342
                     /gene="ade"
                     /locus_tag="KB902_000612"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBB6807463.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(19440..20102)
                     /gene="trmB"
                     /locus_tag="KB902_000613"
     CDS             complement(19440..20102)
                     /gene="trmB"
                     /locus_tag="KB902_000613"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBB6807464.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(20150..20932)
                     /locus_tag="KB902_000614"
     CDS             complement(20150..20932)
                     /locus_tag="KB902_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBB6807465.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(21136..22347)
                     /locus_tag="KB902_000615"
     CDS             complement(21136..22347)
                     /locus_tag="KB902_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807466.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(22340..23077)
                     /locus_tag="KB902_000616"
     CDS             complement(22340..23077)
                     /locus_tag="KB902_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807467.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDTAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            23215..23649
                     /locus_tag="KB902_000617"
     CDS             23215..23649
                     /locus_tag="KB902_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBB6807468.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            23642..23986
                     /locus_tag="KB902_000618"
     CDS             23642..23986
                     /locus_tag="KB902_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6807469.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            24166..25176
                     /locus_tag="KB902_000619"
     CDS             24166..25176
                     /locus_tag="KB902_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6807470.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLKSSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(25245..26189)
                     /locus_tag="KB902_000620"
     CDS             complement(25245..26189)
                     /locus_tag="KB902_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6807471.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(26173..28893)
                     /locus_tag="KB902_000621"
     CDS             complement(26173..28893)
                     /locus_tag="KB902_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6807472.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(28890..30110)
                     /locus_tag="KB902_000622"
     CDS             complement(28890..30110)
                     /locus_tag="KB902_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBB6807473.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKIPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(30391..>30770)
                     /locus_tag="KB902_000623"
     CDS             complement(30391..>30770)
                     /locus_tag="KB902_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBB6807474.1"
                     /translation="EKDAISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIE
                     IVPQNVSKGVVFDRLESIYNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKK
                     ADYVTVSNDKDGVSQAFERILTI"
BASE COUNT         9130 a         6347 c         5387 g         9906 t
ORIGIN      
        1 gtctaactta agcgacgtgt ttcatagttt ttactagtga aaaccagatt actttatttg
       61 tttttagaat caataatgat cgttacaggt ccatcattga cgagagaaac cgacatatct
      121 gctccgaatc gtccggtagc gactgtgatg ccgcgaattc tgattccttc attgaatgat
      181 tcgtataaag gaatagctgt ttctggtcgt gcggcttcca caaagcttgg tcgatttcct
      241 tttttcgtat ccgcaaacag tgtgaattga gagatactta aaatttgtcc tcccacatct
      301 tctacactaa tattcatttt tccttgttca tcttcaaaaa tacgcatttg tgcaattttt
      361 tttaccagat agtccacatc tttttgcgta tcggtttcat gaatgcctaa taaaacaagt
      421 aggccgtagc caatttttcc aatttcttgc tgatcgactg acacagcagc tttacttacc
      481 cgttgaacaa ctgctctcat atctgtcctc ctatccattc gtccggcgta cactgtagac
      541 atcaggtact gctttgattt tatccacgat actctttagg tgggataaat tctggatacc
      601 aaccgtcaaa tggatcgtcg ccattttatc tttattcgtc cgtgcttcaa cgctgttgag
      661 atttttcgtt agcgcattga ctgtttgaag tacatcattc aataagcctg aacgattata
      721 gccgtaaatt tccaaatctg catcatactc ttttcgtgta ttcgatgtat cttcccattc
      781 gacttcaatc aaacgttctg ctacatttgg tttgtcaggc tgaacattcg gacaatctcg
      841 acgatgaatg gatatccctc tgcctttagt gatataacca acgatatcat caccaggaat
      901 cggattacag cagcgactga tacgaattag taagttttct accccttgaa tgacaacgcc
      961 accttcatga cgtactttca ttttgtcagg ttcttttttc ggctgattca tgatttcttc
     1021 tgcttcttgc ttttgctgct cgattttttg ttctttacgt tctttttcag tcagacgatt
     1081 ggccatcgtc aaggggctaa cttctccata ccctacagct gcatagagat catcttctgt
     1141 ttgataatta aaacgatcga gtgcttcttg cagtttgttc ttcgtcaaaa tatctttagg
     1201 cgtaaatcct agatctgtaa tacatttgac cacggattcg tggcctttga tcacattttc
     1261 ttctcgatct tgggctttga agaaacgttt gatcttattt cttgctttgc tagtagcaac
     1321 taatttcaac cagtcgcgac ttgggccaaa tgaatttgga gaagtcatga tctcaatgat
     1381 atcgccgttt ttcaatttgt aatcaagctg caccattttg ccatttactt ttgcaccagt
     1441 ggttttgtta ccgatatctg tatggatact gtatgcaaag tccaatggtc cggatccttt
     1501 tggtaactca gtaacgtctc cctttggtgt gaagacgtag actttatcac taaagatatc
     1561 tccttttacg ccttccataa attcagaagc atcatagctt tcgtcttgaa gttcgagtat
     1621 ctcatggaac cagcttaatt gtttcgtcat accatctggt tctacttttt cattttttcc
     1681 ttctttatag gcccagtgtg cagcaacccc gaattcagcg atttcatgca tttcctgtgt
     1741 tcggatttga atttctaccg gatttcctgc cggaccgatc acggtagtat gcaaagattg
     1801 gtacatatta gcttttggca tggcaatata atccttaaat ctgccgggca ttggtttcca
     1861 ttttgtgtgg attgctccta atacagcata acaatccttg attgaatcta cgatcactcg
     1921 aatagctagc aagtcataaa tttcgttgaa ctgctttttc tgatctttca ttttacgata
     1981 gattgaataa atgtgttttg gccgtccata gatttctgca aaaatcccca gctcttctgt
     2041 tgctattcga atatcttcaa cagtaccact tacgtatttt tcacgttctt ctctcttcgt
     2101 ctgcatcaag tggacgatac ggtaatactg ttttggattt agataacgaa gtgctgtatc
     2161 ttctaattcc catttgatcc ggctgatccc tagacgatgt gcaagaggcg catagatttc
     2221 taaagtttcc tgagcgatcc ttctttgctt atcttctcgc aggtgcttca acgtacgcat
     2281 gttatgtagt ctatcagcta atttgaccat gataactcgt aaatcttgag ccattgctag
     2341 cagcatcttt cggtggtttt ctgctagctg ctcttcgtgg gatttatatt ttattttccc
     2401 taatttggtt acgccgtcca ctaacatagc aacgtcatcg ccaaattctt ctctcagatc
     2461 ttctaaagtg atttctgtat cttcaacaac atcatgtaag aagcctgtag ccactgtatg
     2521 gggatccatt tttaaatctg ctaatatacc tgcgacttgg ataggatgaa taatgtaggg
     2581 ttcgcctgat tttctaaact gtccgtcatg tgcagcagtc gcgtattcgc atgctttctc
     2641 aacaaatgct acatgttcgg gacccatgta ttgactaacg agctttatga caccgggtcc
     2701 cgttaaaatt tcttcttttg tcacaggaat cgatccccct ttcttttttc ggtaaaacgg
     2761 gaatcgggac aaatatctgt ttgataattg tcccaaaatc cgtgcagtta tacgtttttt
     2821 tacggaaatg ttcgcttttt aaaagctttt tcaaacgatt tttcgtatcc attgtataaa
     2881 taattgtttc tattatacaa attgttgact attttttcaa ttctttccgt cgatactctt
     2941 ttattaatga agaacgttag ctgaaagaag gattcattaa ttcccattga tagctagcag
     3001 cacttaataa ataaagaggt gctgtttctg tacgaaggat tcttggtcct aatccacaaa
     3061 gtatcccttt gtgttctaca aaataatcga cttcatcgcg ggataatcca ccttctggtc
     3121 caaagacagc taagattcga ctatctggtt ttgtttcact aagaattttg gctgcatttg
     3181 atttttcgcc ttgctttgct gattcctcat aagcaaccaa gaccacgtca taatcatcta
     3241 gccgctcaaa taaatcttgt ttcgtttcca ataactctac tgatggcacg atctgccgat
     3301 gggattgttc cgctgcctct tgagcaatct tttcaagccg ttgttgtcgt ttcatacgtt
     3361 tttttgcatc ccatttaacg acagaggctg atgccgggaa accaagaaaa gcttgcgctc
     3421 ctaattcagt ggatttctga acgatccaat ccagcttttc ccctttagga tagccactcg
     3481 ctatggtaat cgaacttggc agttcctttt gattttcttc ttttttaatt tctttcagat
     3541 aaacagcctc ttcagtaatc tccgtgattt ctgcaacaat ggctatttga tcattgaatg
     3601 ccaaaaaaac ttcatcctcg ggttccatcc tcataacccg tacaatgtgg tgatagtttt
     3661 ccccttctaa aacaaaatag tcttttgatt catatgattc ttttaaaaaa taccgctgca
     3721 tctattccac ctctggtttt ttcaaaataa ttgcatacca gtctttttgc tggaaaattt
     3781 gatccacgat aaacccttgt tctaacatgg catccagaac tatttgcttc ttctcttcaa
     3841 tgattcctga aacgatcagc gtgcctgttt gcttcagtaa acgccaagca tctgggatca
     3901 tcaataagat gatatctgct aaaatgttcg caacgattac atcactttca atctcgattc
     3961 ctgtcaaaag atcgttagct gatacatgga catctttggc tatttcattc atatccatat
     4021 tttctttcgc cgaacgaacg gctacttcgt ctaaatcaaa ggcatagaca tcttttgcac
     4081 caagatattt tgctgcaata cttagcacgc ccgacccagt tcccacatct agcaatgttt
     4141 caccaccacg caagactgtt tctagtgctg tcaatgtcaa ggaagtcgtg ggatgagtgc
     4201 ctgtgccaaa tgccatacca ggatctagtg tgataatttt ttctagagga tcttctgtct
     4261 ggtagttttc ccagcttggc gcaaccgtca gcattcgcgt aatacgcacc ggatgatagt
     4321 atttcttcca ggctgttgcc cagttgcttt cctctacttc actaactgtt actttatttt
     4381 ttccaatagc tagaccaaac tcaggtaatt gtgtgatacg atctttgata aaaggcaaga
     4441 tttccggtaa gaaagtcgtt tccggaaaat aagccatgac tagtgcgcct tctttcagcg
     4501 atgtaaaatc atttttatct aaaatctcac catattgatc cgactgaaaa tgttcaacat
     4561 ctaaagaatc ttcaatcgcg acaccactcg cccctgcctc catcaaaata ttagcaactg
     4621 cttcgactgc ttcactttca gtttctactt ttacttcatt ccatttcata tctgtcactc
     4681 cttaataact tgggtacggt aaataagtat ctgcttcatt ttgctgtttt acttctacta
     4741 attctgctag ttgctgatta tcccagtgaa gctcgaatac agcttcgtca tcgtcttcat
     4801 ccaaaaaatc aagcaaatcg ctttgccctt gagctaatac ttcatttaga tattccacta
     4861 aagaatcagc tactgatttt gccaaccctt tttttccttc ataagggatt actgctagat
     4921 aattgcgttc atcaaaaaca gatttctgag gattaaaaag aagtacgccg tcttcaaatt
     4981 cgataattgg ttcttgcgaa acgatccctt ctgcatcatc aatctcaaat tgtgctttat
     5041 tttctgcaaa caagcgaaca acgatctcga tcgtatgatt ttttgtatcc caatctaaag
     5101 ctacatcata gtctgtcact tgtttttcaa ttatttcatc taaatatgtt aatagatcct
     5161 tctttttcat tttctttcct ccaaccccaa tctttctcga tttggttttt tctttgtaaa
     5221 gagatataag gatttcccga cacaacaaaa cgcaacggct tttctgtcca tacacctttg
     5281 tttgggatac cgattctagg caaagcattg atcttttttg gtgtcttttt tttctcaaaa
     5341 actaagcgta acgaactatc tgctatagac tgaccataaa gttcttgagg aattgctaat
     5401 gcttccacta attttcccgg accgttgctg atatctggac cagtttttcc gccacgattt
     5461 ttactcattt gatcaatcat tgcggcgggt tcgattgcac gtatcattac tccttgagga
     5521 atcccttctg gctgagtaat gatgttcaaa atccgatgag tatgcatcgt gtaaaggtag
     5581 atcgtacctg gtttttcata cattgcccgc acacgcggtg ttcttcttaa accatagcta
     5641 tgggcggcct cgtcttctgg acctaggtat gcttccgcgt ctacaatata tccagctaat
     5701 cttccttctg gtgtgtcatg ctccaaatac atccccaata aatcccgtgc cacttctggc
     5761 gtcgttttat tccaaaaaaa ttcatctatc ttttgtttat ccgtcatttt tctcacctac
     5821 tttatcatac acaatattag ttggataagc tatgaaaaca aaacaacaga aggctgttct
     5881 ttctaggcat cttgctaaat atgatataat taagggacgt aaaaacaaga aggaggaaaa
     5941 tcctatgcaa cagccattgg cttatcgcat gagacctcga acgatcgatg aagtcgttgg
     6001 tcagcagcat ctagtcgggg aaggaaaaat catacgccgc atggtcgatg ctcgcatgct
     6061 ctcttccatg attctatatg gacctcctgg tactggaaaa acgagtatcg caagtgcgat
     6121 cgccggctct actaattatg catttcgcat gctaaacgcc gctacagatt caaaaaagga
     6181 tctacaagtt gtagcggaag aagcaaaaat gagtggtaca gtgatcctct tattggatga
     6241 agtacaccga ttagataaaa caaaacagga ttttctgctt cctcatttag aaagtggccg
     6301 aatcatcttg atcggagcga ctactgagaa tccttatatt accatcaatc cagcgatccg
     6361 cagccgtaca cagatctttg aagtcaaacc attaacagaa caagacatcc agttggcagt
     6421 cgaacatgct ttaagggata aagaacgcgg ccttggacaa caagcaatcc agttagacga
     6481 agatgctctt cttcaccttt cgcgtgcaac gaacggcgat ttgcggagtg cattgaatgg
     6541 gctggaactg gctacactat cgactccttc agataaagaa ggaaggattc atcttacact
     6601 gtcgatcatt gaagaatgtg tccaaagaaa agctcttacc catgacaaaa atggagatgc
     6661 tcattatgac gttatttcgg cttttcaaaa atcgattcgt ggaagtgatg tggatgctgc
     6721 acttcattat ctcgcccgtt tagttgaggc aggtgatctg gcaagtattt gccggcgtct
     6781 gatggttatc ggttatgaag atataggttt aggtaatcct gctgctgcgg ctcgtacagt
     6841 gaacgctgta ttagctgctg aaaaattggg attgcctgag gcacgtatcc cactagcaga
     6901 cgtcgtcgtc gatctttgct tgtcgccaaa atccaattct gcctacatgg cattagatgc
     6961 agcacttgct gatattcgag agggcaaagc tggagatgtt cctgatcatt tgagagatag
     7021 ccattacaaa ggtgcgaaat cactcaaccg tggcgtgggt tatcagtatc ctcatcattt
     7081 tgatcaggct tgggtcaatc agcaatattt accagataaa ctgaagaatg ctcagtatta
     7141 tcagccaaaa gatacaggga aatatgaaca ggctctgggt caacagtatt accgtataaa
     7201 agagtggaaa aagcatcctc caaaaaacta gacaagaaaa cggttctgtt tctgcgagct
     7261 ctctcattgc tctttttaaa ttcatatgct actatagagg tgggaaatct gtgatgttcg
     7321 aattgtcctc tttgtgtgtt gaccgaacat ttttattgat atcttgggac ccgtcttgtg
     7381 tcactgctgg taacatgcct tatcatttgg tagttcgaag ctacgaccat gggacccacc
     7441 tgcttgaatt cgcgggatca atactacagg acaaacaacg gcattaacgg agattaccat
     7501 cttttaaaga ataaagcaat ttgctcttgg caaattgctt tttctatttg ttgcttattt
     7561 tggaggattt gttcatgatt aggattttaa tgattatcgc cactttagta ttattattcg
     7621 ttagctatta tttatttaat aaacaggata tcttttttgt attgatcaac aaaaatgata
     7681 aaaatcaagg attcctacaa ttttacggag ctgcatatgc tgttttaggc gtaatgggta
     7741 ttttaacagc ttttttcaat caacgcttta ttgccttggt ctttttactg atcgtaatta
     7801 ttgtttctgc caccttcagt atccgatttg caaaaaaaat tgctgaacca aagcagtaaa
     7861 taattctctt tttccctaaa gtgttctaca ataaaagagt acaatacgat tgacttgagg
     7921 agtgaatgct tatgttacaa caatacaaaa aaatcatggt tgccgtagat ggttctgatg
     7981 aagctgaatt agcttttaaa aaggcggtca atgtagctat ccgaaataac ggagaacttc
     8041 tattagcaca tgtcattgac acacgttctt tccaaaccgt ttcatccttt gatggaatgc
     8101 ttgcagaaca agctactgaa atggcaaagc aaacattggc agattatgaa agcaatgcga
     8161 agaaagctgg cttgaataat gtaacctctg tcgtagaata tggctcacca aaacaaatta
     8221 ttgccagaga aatcccagaa gataatcaag tagatttgat tatgttagga gccacaggat
     8281 tgaatgctgt agaacgttta tttattggtt ctgtttctga atatgttatt agaaacgcag
     8341 cttgcgatgt gcttgttgtc cgaactgatt tagaaaacca attgccagct aaagaccaca
     8401 ccaaagctta acacgtagac gacctgccaa ctatcggcag gtttttttgc acaaaaaacc
     8461 gtgataaaaa caaaagacgc ggcaagcact catcggtctt tataatgttt aaaataaagg
     8521 gaaaacagtc aatgagttca agtaaaataa aaaaaagtga acaccagggc gattagtcgc
     8581 cctggtgtgg tttaaaacga cctaagcatg ccaaagctta ttggttcgtc aatgtggaag
     8641 tttccgatga atctgatacg aaaaaatatg aagtatcgat ggcggatacc gattttatcg
     8701 ccaaactaaa attttatttc gggttcgggt accgcgagaa ggcaagtgct acattcggta
     8761 aatcattcaa gaattgatga aaggctaccg cttgccattg caaccacaac gatactcctg
     8821 aacgcgatgt tggtgagatt tccaaagaga agagctgttt aatgcaacgg tattaagcaa
     8881 atggcaaaag gaagtcatgt agacaaagtt ttttatcaaa caccatatga tttcgcctga
     8941 acgctggttt agctcagaat acaatgatgt ggtccacgag acattaccct cagtcagata
     9001 aaaaaagctc tctgacagaa ttacacatcg ataaatatta agtaaatgtc agcgctagtt
     9061 gaactttctg acactttcag gtacactgga aaagacaact acacgaagga gggaaaatac
     9121 tatgatgcgc atgactaaaa taacaagtaa tgaaaattac caacgatacc atatcgcatt
     9181 tagccatgca attggtttta cagttgctgt tgacgggaca agtttgtcca aaacagttga
     9241 attcacgtaa aatcaatggc catctcaagg tatttttctc atgataatct gagtttaaat
     9301 aacacaggcc atggataacc atggcctttt tgagtggtct caaggagaga gatcatgatc
     9361 atacaagcaa tttctattaa aaaaacaatc ggcgggaatc cattatttga ggatttatcc
     9421 tgtcaaattg aagctggtga aaaaattgcc ttagtcggta tcaacggaac tggcaaatca
     9481 acctttttac aaatcttgac cggcagagaa ggtgtcgaca gcggtgttat cagtcgcaaa
     9541 aaaggcttaa agatcgggac ggtcgaacaa gaacttacag tttccgaagc gaccgtcaac
     9601 ccctacttgc tccattctgc cgctgagata caggacctca aacagcaaat gagtcgctac
     9661 gaagcattga tgacagaacc agatacaaac ttagagaagt gtctggcccg ttacggtgag
     9721 ctgcagcatc gctttgaaga actaggcggt tacgtattag aagaccggat tgcagcgatc
     9781 ttgcaaggct tagggattcc acaccgtcag gaagcacggt taacagaact tagcggaggc
     9841 gaacgagtta aagtcgcttt agccaaaatt ttagcagccg atgccgattt acttttactc
     9901 gatgaaccga ccaatcattt agatcttaac agtattcgct ggttggaaaa ctatttacag
     9961 aatacaaaaa aatcggttct ggtcgtttct catgatcggc aatttctcga tcaagtcacc
    10021 acaaaaacat gggaactgga agaaggtgca ttgattgagt atcccggaaa ctacagccgt
    10081 tttcgagtct tgaaagaagc tcgcttggct gagctgacaa aaaattacga actgcagcaa
    10141 aaagaagtcc agcggttgaa agtcatgatt cgtcgttttc gtcagtgggc acatgaagga
    10201 gacaatgagt ccttcttcaa aaaagccaaa gaactggaac gccgcctggc gaaactgaca
    10261 ctcgtcaaac cgccacctcc cccgaaaaat cggctgcaaa gcttgtctaa tggtggaaaa
    10321 tctggcaaag aagttttcat cattcaaaac ttgcaccagc agtacgctga tcaagtacta
    10381 ttcaaagaca gcagttttgc agtctatcgt ggagatcatt tagccatcat cggcgacaat
    10441 ggtgcaggaa aatcaacctt actcaaatta ttactcggtg aggaaaagcc ttacggtggc
    10501 accatcaaat taggtagtag cttgcaaatc ggttatttgc cgcagcagct gcagtttgcc
    10561 gatcccgata gccgtttgct ggcttacgcc atcacattga ctggaaacga agaagtcgct
    10621 cgacggcaat tagccaaaag tggcttttat caaagcgatg tgggtaaacg gatcaaagat
    10681 ttatccggtg gtgaaaaaat ccgtttggcg ttgctgaaac tctttttaga aaaaatcaac
    10741 gtcctgattt tggatgaatc aaccaatcac ctcgacagct atgctcgaga agaaattgaa
    10801 gaaatgctgc aagactatca aggaacgctc ctagcagtca gccatgaccg ctactttttg
    10861 cagcaacact tccaagaagc actcgttatt gatcaggagc agatcagccg ccagccgctc
    10921 ggccaactga ttgactagga cgttttttcg caacaaaaaa cttgattttc atacctgtgc
    10981 tttcacgatt caggcaaagt acaggtggaa aatcaagttt ttattattcg atcaatgaat
    11041 gtttcggatc ggttttctag ctaaacataa agcgaagaat aaagtcgaca gcccacgagg
    11101 ctgatctaaa aatgtttttt ctttttacat atgtaatgtc ccttataaag atgaatgaaa
    11161 ataaaatatt gggattttcc tgaaaatcaa taaataaaat gccagtcttt tcccttttga
    11221 ccacttttcc aagcaaaatt ccctaagaag atcctgtaaa aaagaaggga aattgaagtt
    11281 aaattaccat tttgcggtct tctccgcaaa aaaaacacat gcaagaattc cctcttgcat
    11341 gcgtttcatc ttttatccta acgaatgctt tggcttagcc gcgcagacgc tccacatcac
    11401 gggcaatcat tagttcctca tctgttggga tcactaatac tcttactttt gattcttttg
    11461 tagagatatc tacttcttca ccacgcaatt cattcaacgc tggatcgatt tcacaaccaa
    11521 accaagacat acctttgatg atttcactac gtacatgtcc gtcattctcg ccgataccag
    11581 cagtaaagac aattgcatca acaccattca tcgttgtcac ataaccgccg atgtattttc
    11641 ggatgcggtc cacgaaaatg tcataagcta aacgaatatg ttctttttca tagttctttt
    11701 caagatcacg catatcacta gacaatcctg ttaggcctag cagaccagat ttcttgttca
    11761 aaacattgat catttcatca atatcaatct ctaatttttc cattaaatat gggagaacag
    11821 ctggatcgat atcacctgaa cgtgtaccca ttgtcacccc agctaatggt gtgaatccca
    11881 tagaagtatc catggattta cctccatcga ctgctgtgat cgatacacca tttcctaagt
    11941 ggcaagtgat gatttttagt tcttcgatcg gtttgttcaa taattttgcc gcacgttccg
    12001 acacataacg atgacttgtg ccatggaagc catattttct tactttgaaa tcttcataat
    12061 aagacaccgg taagctatat aaataatttt gctttggcat tgttgagtgg aaagatgtat
    12121 cgaatacagc cacactcaaa atgtcaggta aaatcttttt aaacgctttg atccccatta
    12181 agtttgcagg attatgcaaa ggagcaaatt ctgctaattc agcaatgcgg tccattactt
    12241 tctcatcgat cactactgaa tccccataag tttctcctcc gtgaacaaca cggtgcccta
    12301 ctccggtgat ttcatcataa gagcttaaaa tttgcagttc aatcaactga tctaacagca
    12361 tttttactgc tacttcgtgg ttttcgatat ccatgatttg ttcgaatttt tgattatcgc
    12421 cgtacttgat ggtaaaaata gaatcttgta aaccgatacg ttcgacgatc cctttcgcaa
    12481 ctacggtttc ttctggcatt tgatataatt gccatttcaa acttgaactc ccagcattga
    12541 ttgcaattgt tttagacata tgactctcct tctcgttgaa tgattacaga gcagatgatt
    12601 tccagttttt aaactcgttg aaaaattccg tcaccttctc tggttctttt aatgaagcaa
    12661 gtttcacaag caagacttct tttacttgtt gtgcttgtgg tccttttttc tgtaagatca
    12721 aaatactttt ttgcgattgt ttattacgga acaattcatc tggcaattga atcattcctt
    12781 gaagataacc ttcttcttta aaccattttt tgatttcttc actttgatcc gtttctaaaa
    12841 atccactcgg catcaaaaac aaaccaaaac catccggctt cacatatttc attgattgct
    12901 ctagcaataa atgatgtgca taactatggc cttcttcggt acttgttaaa aactcttttg
    12961 ctttttcgtc attcggataa taaccgattg gcaaatcgct gattgcaaaa tcgacaggat
    13021 ctattaataa ttcctgcaac ccgtcttgat gaaagtattg aacatttgct tgtgtcaaat
    13081 cacttgtaga agctgcgaca gccaacaatg tatcatcaat atccacacca attccttctg
    13141 tttggtaccc cgcattcgat aggtttaaaa gaactgttaa taacaagttg cccattcctg
    13201 ccgcaatatc cagaatctta accggtgctt ttttatttgt gtatagttgt tcaataagaa
    13261 aaacaaataa aaaaccgata ctatcaggag tgagttgatg gttcgcctgc aaatgttctg
    13321 tctggctgcc cttcaataaa agtaattgag acagtctgcg ccattcttct ggctcgaaag
    13381 aaagtttctt caactcttca taaagagctg tgatccgttg cgttgtctct tttgtcggca
    13441 ctccatccac cacacgtact tgataatcat ctattaaatt ttctgcattt tcgacatagg
    13501 cttctaaaaa ggaagttccc aatgcattct gtaaaagctg aatagcttcc aggttttgat
    13561 taaacccttg ttccattttt tctggtaaca tggtgcacct catttctaga tatattataa
    13621 caattttttc acctgtttaa ttctatcgaa caattgacaa aatttcaatc gttttcactg
    13681 ttttttattt gtgaaacggc aaacattttt ttattaaaaa cagtgttata acagaaaaga
    13741 gggcgttttc acgaacattc catcattctg tactagtatc tgtatcattt tttacttctt
    13801 ctgtgaaccg aaagataaac ggtgagactt ccacctctaa gaatagggac tgttgtaccc
    13861 actgatatgt tacagatcca gttgtgtagt aaaaaactcc ttccgaactt tcggcaagcg
    13921 tagactgttc cgataaagcc atctgcttca ttatttttgc tatataataa tttttgattc
    13981 gtatattaag atccattgac aaacggtagc tttctaatgc tgccatcaat aaaaacgtac
    14041 ataaaagaaa taaaagcaag acagaaaata aaatagagcc cttataacat tttctactga
    14101 tcggtttttg tccatatggc atatccatct tctccatttt caaagtgtac ataaaaagaa
    14161 attgtgtgtt ctttttccaa taattgaagc tcagtgatac ttgttaacat aggttgatgt
    14221 ccgccggaag ttcttctttt acgtatcatt gcctgatatc tttcgatgat atactgttta
    14281 tcctcgatcg tgtagtgcag ttgctgattt ttcacagaga cattgtgact gctcttgagt
    14341 tcttcttcta attgtgctaa aaatattagc cactcttttt gatctttacg ctgcaaaaat
    14401 tcacttactt ggatggtttg ctgaatcaaa agattgaatg tgagcaatag actgctcaat
    14461 atcatcagtc caattagaca ttcaatcagc gtaaatgctg gaattacttg ttttttcaat
    14521 actgatcgct tctttctcca tattgacaaa cactttttcg attactccat tattatcgac
    14581 aatttggata tcgtatggga tcatttcttc ccttcgctct ggtcttttgt gatacatccg
    14641 ctgcgtcttg atatcttcat aaatcattcg aataaatagc agttcctccc cacttttctt
    14701 ttctgcctga agcaaaaaca gctggccaaa gctcactaag tagacacaga cagaagcgat
    14761 cataagcgct gtaagggact ccaacaaaac aaatcctgtt ttattcaatt ctttttgtat
    14821 agcgaccact ccctatctgg aattgatacg taatcgtccg ctctttttct tcccaataaa
    14881 attgataagc ttttagtgaa ctttcattcc cggttctagc agcaaaagta atagaagcat
    14941 ggcgtttcaa ggtaatctca tcaggaatat ctaatacttc ccaatttatt ttatctggat
    15001 tcggaacatg aaaaatgatt tgattctctt cactattcca ataaaagcct gtttggatct
    15061 gattcacaat agcgattttt tgcgtagaat agattcgttt ttcaaattgg ccgaaaaatt
    15121 gatagactgc caattcattc ttccatgcag aaaatgcgag aactggaaaa gaaaggatcg
    15181 ttgtaagtaa taaaatcagt aagagtgatt caaacaacgt atatcctgat gctaaaacct
    15241 taccttcaag gccgctgata gatttctgca tgttctcgtt tgatatagcc ttcattcaac
    15301 aattcctcca cagtaggaac tcttccatta ttttgaagcg catagagctc tttttgtgtg
    15361 tctaccaact ggatgatcgc ttcacgactt tcttggtcta catgattcct ataacgcgac
    15421 aaattaggga cgaacaacaa cactaataca ctgatgatca gtaagacgat tagcatttcg
    15481 atcaatgtaa aaccgctata ataagatatt tttctctttt tcatggcaaa acctcctcta
    15541 tgcttccgta aacaggtaat aaaacagcgg cataaactaa taaaatcaaa gccgctacgc
    15601 ccaaaaaaat gattggctga ataaaatgca tccagtgatg aagacgtttg aaaagctgtt
    15661 ttcttgtcca ttcgctgtaa aaaatcagtt ctttacctaa acttcccttt gcctctccct
    15721 gtaaaacaat tttactgaat tcttctgata gaaaacgata attctggaac tgctcagcca
    15781 atgacatacc tgcctccaat ccttgaatca acttagaggc aagatgctga atcagacttt
    15841 cttgtttcgt ttcctttaag cagactatga tttgccttaa ttcgaaacct tcatgaaaaa
    15901 gctttccaat ctctagtgac aaataagccg attgatacaa ggaatatatc ggtccaatca
    15961 ataattgtct gcttatccat tcactctgat caacaggaga caacttcatc agacgatacc
    16021 ttactagtaa agccaataga gtaaccgcta ggatgaatag tagaacatac caatgaaaga
    16081 cttgtatcag ctgaataccc caatgctctt gcatgaccat tcctgaacca ataagctgag
    16141 gcaaaacgaa caaccgcata ctaaacaaga tacctagcaa aaaggtgagc aatagcatcg
    16201 gatatgcaag cagctttttc aaatcattgc gaaatccttc aacaagccga aactgtttgg
    16261 caatttccaa caaagttgtc ggcagattcc catgacgttc agctaactcg atctgtacca
    16321 gttgctctgc tccatatcct atttgcgaaa gtacctcact aaacgcttgc ccttccttta
    16381 gctgatgttg gatatttgcc aaaataacag gtggaaacga acggatcgtg agtaataaat
    16441 aaagggattc ttgcagacta aaaccagata aaagcagttc tcccatggtt tgtgcaaact
    16501 ggttttgctg gcttcttgtt aatcctttag aatagttctg actgccaaat attttcctga
    16561 gcttcttcat aactttcctc ccatgatttt tttactgatt cttcctccat aaattgataa
    16621 ctccataaaa cagaaggatg gtgattggca tcttccaaaa gttcttgata aatgacacca
    16681 gctaaacatt cagatagctc ttcttttttc tttgtcagtt catggattct gaccaatgta
    16741 ccttcaagat tgcgtgcatg tacggttgca aaaacccggt gccctgttag tgctgctctt
    16801 accgcagcat gtgcagttga ttcatctctt atctcgccaa tgattagcaa gtctggacga
    16861 tgccgtaatg cgagtttcaa aagtgtatca taagtctgtg ctattttcgg attgatctgt
    16921 agctgcagaa aaaacggttc ttctatctct acaggatctt cgatagtaat cacttgcaat
    16981 ttttcttcca aagccaaccg atacattaga gaagtcttgc ctgatccgac tggtccgctg
    17041 aaaaggtata atccacgtct gacggttttc tgtaaaatag ttgcaaaatc tcgagaacta
    17101 aagcaacgat ggggtgtttc aaaagtaccg tataatagcc gaatcactaa actctctcgt
    17161 tgaaggtaat ctcctacaga agacaaccgc agacgaactt cctgtttttc taaagaataa
    17221 gtaaatgcac ctaactgagc ttttcttttt tctccgatat ccatctgtcc caaatactta
    17281 aatcttgaga tcagttgctg tccatctgcc gaagagactt tcttccagaa tgttcgtttt
    17341 tttccatagc gaaaatagat gtaaaatact tctgaagctg gcaatatata tacgtcttgg
    17401 gcatgtttgg caaaactttc acttatcatt tgatccgata atcgttttat ttccattatt
    17461 ctcccctcca caaaaaacat acgtcttttt gatctttttg tttcaaataa aatgaattta
    17521 caaaaaaata ttggcaaaag ccgaatttat gttatactta taaaaattta tcttgggagg
    17581 cactccattg gaaacaacat taaggaaata tatcgaagta gcaagtaaaa aaaagcctgc
    17641 tgacctagtg atcaagcatg ctaagatcgt caacgtcttt acgaaagaaa tcatggaaaa
    17701 agatgtagca atctgcgaag gaatgatcgt aggaatcggt gaatacgaag gaaaaagcgt
    17761 acataatgct aatgggcaat atctagtgcc aggattcatc gatggccatg tgcatatcga
    17821 aagctcactt ttatcaccaa gcgaattttc aaaagtatcc ttgcttcatg gagttactac
    17881 tgtagtgaca gatccccatg aaataggaaa cattgctggg agtacaggtc ttgagtttat
    17941 gatagaagat gcaagacaaa cactcatgaa tatctttttt atgctacctt cttgtgtacc
    18001 tgtaacccct tttgagacca atggtgcaaa tttaaatgca aaaaaattag cccctttttt
    18061 acaaaaaccc gaagttttag gcttagctga agtcatgaac tatcaagcag tagcaaataa
    18121 tgaaacagac atcctagaaa agatccaatt gatgcaccag cataagaaaa aaattgacgg
    18181 gcatgcagct ggtatcggca tggaagagtt aaatgtttat cctgcagcag gtattcggac
    18241 ggatcatgaa gctacaactg caaaagaagc taaagaacgt ttggatcttg gtatgtattt
    18301 aatggttcga gaagggaccg ttgcaaaaga tctggcatcg ctactaccgg cgatcacacc
    18361 tgaaaattca agaagatgct tctttgtcac cgatgataaa ctgatcaatg atttagtaaa
    18421 agaaggatca atcgatcata tcgtccgtca agctattgca cttggaatcg atccattaca
    18481 agccattcag atggcaacat tgaatgcagc agaatgtttt gatttgaaaa cactaggtgc
    18541 gattgcccct gggtatcaag ctgatttctt cttaacagac gatcttacca agctgccaat
    18601 tcatgaagtt ttctataagg gaacattagt tgttcaatct gggcaactcc aagaccattt
    18661 atttgctgat cattcaaatt catatacgtg ttgtctgcca aaactaaacg ctcaaccatt
    18721 aaatccacat tcgttagagc tgcttctttc ttcttcacaa gcccatgtga tcgaaattat
    18781 cccgaatagt ctagtgacta aagatttggt agaaaaagtg gaccgacaag gcgaacgatt
    18841 cattccttca atcgaaaaag accaattaaa gattgcggtg atcgagcgtc accatcaaac
    18901 gggaaacatt ggattaggca tagtgaaagg atttcagctg aaacaaggag cgatagcgac
    18961 aacgattgcc catgactcgc ataatctagt tgtcgttggg acaaacgacg aggatatgct
    19021 gtatgctgct aatcttttga ttcaaaaagg tggcgggatg accgttgtca acaaacagca
    19081 ggaaatagct tgtgtttctc ttcctatagg cggaatcatg acacaggaac ctttttcgat
    19141 cgtctatgaa cagttgaatg aattaataac taaagcacat caactaggag cagctaaaac
    19201 ctttgatcct tttttgacac tttctttctt aacattatct gtcatacccg aattgaagat
    19261 caccgacaaa ggattatttt cattttctcg cttccaattg attccacctt gtggaaaaac
    19321 cgatgaaata aatacatttt aaatcaaata aatcccagaa aatacattac atctgtaatg
    19381 ttcattttct gggatttatt tatggatatt aatgttttta tgaaagcaga aagttagttt
    19441 cacagacttt tctttttggt cttatcttga aattgagctt ctactcgata aatacgttga
    19501 ccttttgaag aaaatttttc ttcatactcc gtcataatat tgccttcaaa ttgactttga
    19561 tgtaaatcta accatacctg tttgaggatc atgccatatt gagaaaaact tgccagagaa
    19621 tactcaaaca atccttgatt atctgttttg aaatggattt ctccatttgg acgaagaatc
    19681 tgttcatcta cagcaagaaa agtcttatat gtcaatcgcc gtttttcatg acgttttttt
    19741 ggccatggat cggaaaaatt cagatagatt tgatctactt cgctgtcagc gaaatactct
    19801 gtcaacgctg atccatccac atgtagaagt ttcaggttag gaagcggttg ttcgatcaac
    19861 ttgtctagtg caatcgaaac aacactgacc tgcatttcta ctccaatata attgatttca
    19921 ggatgggctt ttgccattcc agtgatgaac tggcctttcc ccataccaat ctcaatgtgg
    19981 attggatgat cgttttcaaa caattcattc cattttccct tccacaatgt tggatcacta
    20041 attacaaaat tcgggtgagc cgctaacatt tccgctgctc ccggacgatt tcggacacgc
    20101 attatttatc tccattcctt tcctctaatt aaaaaggtct ggccaaacct cagccactga
    20161 aaattcgttt taattgtaaa atttcttcgt tcatccgtcg atgatcttca cgtttgcaat
    20221 atctggtgat ttcttggagc aaattcatgg ccgcatacca atgaaatttt tcaagcattt
    20281 cgtcagtcgg gcgtatgcca taactgatca gccactgatt ccagctagac agtggcacat
    20341 aatttcctaa aatcgttgca atatccaccg cagggtctgc aaacatgatt gaatcccaat
    20401 cgactagata taaataattt ttacatacta accaattacg atggtttaca tctccgtgta
    20461 ctactgataa gttttcctta tctattgacg ggatctgctc acgaagaaaa cgatggacaa
    20521 tttgcagaaa ttgatttttc tggagttctt ccggtaattc tttttcatat ttttgcagca
    20581 tcttctccgg cgtcatgaca cgaccaccga tacgggtcag catggtttta agagaatttg
    20641 aatgatgtaa atggtacaaa acatcaatca cgtcgtttct ttgaccaatc tcattaggag
    20701 tcagcaagcg accttccagc cactcttgtg ctgtcaaagt atcgccattc cccgttcgtt
    20761 ttgtccaaac aagttttggt gtaattcctt cccttgaaag agcagccaac atcggagtcg
    20821 tgtttcgttt aataaagact ttgtcctcat cacgcatgcc tatgtatgtt tttcctgtgt
    20881 cgcctttgat gggacgtaac cgccactctt ggtctaactg aaactccatc atgcattctc
    20941 ccgtcctctt actctttgtt ttgcagtact tattattcta gtcgcctgaa cactacacgt
    21001 caagcacata tacgttcttt ttcatttaat tgccattcaa aaaaccagct tttctcaaaa
    21061 aaaatagaac gaacagcatt cttactgtca acgctctatt tttcattctc atttttaccc
    21121 tacacagctt tgttttcagt ctgacatctt cttcaaacga gttggtacat atagtttaac
    21181 aaagagcata gtaacaatca aataagccgc tagcggaacc catcgctgct gcccatctaa
    21241 tacgactgca gcaatcaaac caaaaataac cgacgcgata attaataccc atgtgagtag
    21301 atactgaatc gcctgcttct tctgattctt atggattgga taaagctgaa cgagaaccat
    21361 atagcggaac tggttcgcta aaggtaacag ttggaaaccg atcaaatata aaaataagaa
    21421 accgataatc agactaaaat aaaagtcgac tactccggca atcaataacc cacctataat
    21481 tactaatcgg aaataaagac cactaaaatc agaacctctt gccaatcttc ttgcaaacaa
    21541 gtaaagataa gtgttttttg attctctttt aatatgagtc aatataggat ccaaatagcg
    21601 tcttcttttg atctttgccg taatttcagg aacatctgtg aataaattga taaattgata
    21661 gatctgatgc aacctatgtt cttctacatg caccattttc tcccaatcca atcctttttc
    21721 ttgttgcttc cacaaaaacc agtaatatag acttgcctgt actaatgcac ctgctattcc
    21781 tgcccatatt agccaataaa atgatagaaa taaaaagatc agagaagaaa aaaaccagcc
    21841 taatttccaa taacgaataa cttgttgatc tagtcgaaac aattctgctc tcttgatttg
    21901 cagatgactg aatttcaaac tccataatat gatcagatag acgaaaaaca tcgaaaagga
    21961 ttgctccgta ctaaccacca ctaatggcat ggccaatccg catgccaata tcaaaaagat
    22021 caacggaaaa atgcaagaat agcgaaaagc tcgttccaaa taggtttgca tttctttttc
    22081 tttaggaagt aaaaaaacaa tatctgctgc ctctgcaaaa gtagccatct tacccacgaa
    22141 taaacagagc atccaaaata cagagattat gagccctcca attgcaaacg gtggctgcag
    22201 ggttttcaac caattagaat aatataatcc cacaccgcca atcaagaaaa gacaaactaa
    22261 aacaaaatga tcgttcaata cataacgcat atatttcatc attttctttt gatgtcttgc
    22321 taaacgtttt tgaaaaaaac tactcatgtg cctgctcctt tgttaaagca atatagattt
    22381 cgtccaaaga agaatccggc agctgaaatt cttttctcaa catctcaaga gaaccgtctg
    22441 ctcgtatctc tccgttatgt aagaccacaa aacgatcaca atatttttct gcagtagcta
    22501 aaatatgcgt agacatcaaa ataccggctc cttctttttt catttctacc atcaattcaa
    22561 gcaatgcatt gatagctagt ggatccaagc ctaaaaatgg ttcgtcgatg atatataaag
    22621 aaggctcgat caaaaaggcg cataagatca tcactttctg tttcattccc tttgaaaaat
    22681 tagctgggaa ccagtcaaga cgattagata accgaaaagt ctccaacaac ttttctgctc
    22741 ttttcattgc tgtatccata ggtatatcgt aggccatcgc agtgacttcg atatgttctc
    22801 tcaatgtcaa ttcttcatat aaagaaggag tctctggaat atacccaatt tgtttgcgat
    22861 attcttccgt atttttcttt aaggatagat gattgatttc tatcgttcct tttgaagctt
    22921 ccagcagacc gataatgtgc ttgatggtcg tacttttccc tgctccgttc agtccaatca
    22981 accctactat ctctccaggc tgtacatcga aactgatatc ttttaacaca gggagatgtc
    23041 cgtacccccc tgtgacatga tcgataatta aactcattct ttttcctccg ccatttattt
    23101 ttatttatta taccacgaag aaaatgacgg tattttgttt ttttccttac aatagcttta
    23161 acttatggta aagttaagct gaagtattta ttctttatag aaaggatgtt ttatatggaa
    23221 aactgtattt tttgcaaaat catcaatcaa gaaatcccaa gctataaaat atatgaagac
    23281 gacaaggtct atgctttttt agacatctct caagcaacga aaggacacac attagttgtg
    23341 cctaaacgtc atgtagcaga tatttttgaa tatgatcccg aacttgcagg agaggttttt
    23401 tcgcgtgtgc ctaagattgc tcaagcattg gaaaaagctt ttccagaaat gaaaggtctt
    23461 aatatcttga ataacaaccg tgaactagcc tatcaatctg tttttcattc acatatccat
    23521 ttagtccctc gctacagcaa agaggatgat ttttctattc actttgtcaa tcatcaagat
    23581 agttatggat cggaagaact aaaagctatt caagaaacaa tcgtaaagca ggtgtcctgc
    23641 gatgattaaa aactttttca aaggactgtt atttggagct gctgctggca ctgtcggagg
    23701 tctgttattg gcgcccagga gcgggaatga aacaagaaag aaactgatcg aagaattgga
    23761 agaagcaaca actctgacaa atgatttaaa taacagcctg aatcatttta aaagcgcatt
    23821 gatcgaaaca aaagaaacag ctgaatctgt gattcctgct ttccaagaag caatcaaaaa
    23881 agatatcgaa gattttaaat tccaagccga accacgtatc acacaaatca atgaacaagt
    23941 agaaaaacta aaagctgatc tgccagagta tcctgaacaa atataataat gattattttc
    24001 tcaacagatt taactatata agtgagaaaa gtttgcgtat ttcctaggaa tgtgatgaaa
    24061 ttttgaattt tgtttgaaac taccacgaca acgtttttaa aggaaatggg atatggtata
    24121 gttaatatat aaaaataata actaattaca ggagtgcaaa ttttaatgaa aaaaaaatca
    24181 attattttgg cagctactag tgcgttggct gttttaactc tagcagcttg ttcaggcgat
    24241 actaataaag atatcgcaac gatgaaaggc ggaacgatca ctgtatctga tttctatgat
    24301 gaagcaaaac ttaaatcatc gaaccaatcc ttagtacaac ggatgatcat ttataaagta
    24361 ttcaataaca aatatggcga taaagtaacc gataagcaag tggatgcaga atacgacaaa
    24421 caagcgaaat cattaggtga tacttttgaa tcacaattag aagctgctgg atatacgaaa
    24481 gatacttata aagaatatat tcgtaacaat ttagcttttg aagctggctt gaaagctcac
    24541 gtagatatta cagatgacga tttgaaaact gcttggaaat ctttccatcc agaagtagaa
    24601 gcacaaatca tcaaattatc aagtgaagat gaagcaaaag atgtgaaaaa atcagcggat
    24661 gatggagatg atttctctaa attagccaaa gacaaatcaa ctgatacaga gacaaaagaa
    24721 gatggcggta aagttaaatt cgactcaacg acaacaacta ttcctgcaga agtaaaagaa
    24781 gcagctttca aattgaaaga cggtgagatc tccgatgtta ttactacaac aaatcctact
    24841 tcttatgcga cagaatacta cgttgtcaaa atggtgaaaa accaaaataa aggcaatgac
    24901 atggataaat acaaagatca actaaaagat atcgctactg aaactaaact aagtgacaat
    24961 gcattcacaa ctaaagtaat cggtgaagaa ttaaaagatg caaatgtaaa aatcaaagat
    25021 gatgcctttg aaaatgtgtt gagtgcattc acaacaactt catcaagtac gaaagactca
    25081 agtgaaacta cagcttcaac aaagagttct gacacaaaat caactgattc aacaaaagaa
    25141 tcttcaactg aagaaacaac tgattcatca aaataaaaga aaacaaaaaa agcgaagact
    25201 tatgtctcgc tttttttgtt ttgaatgaaa aaaataaatt tttgctataa atcttttggt
    25261 acatagaaac ttcggttgtc cataccgaaa atccgatcgg tgtattttcc tggttctgtt
    25321 tgacgaatcg aagtcaacat catctgcatc gaagcatcga tattgtcgat ttgatgtaat
    25381 atttctgctt ccattattct tggacgtaca ggtgagccat attctaataa gccatggtgt
    25441 gctaaaacca tatgacgtaa tacgagaaca tcttcgtcag cttcgctgat tttcaacgca
    25501 agacaggctt tagttatttc ttcgtcaatc aataccagat gaccgatcaa atttcctgca
    25561 agcgtatatt ctgtcgacat aggaccggaa agttcaatca cctttcctaa atcatgcaaa
    25621 atgataccag catacaacaa tgctcgattc agctcaggat attcatcggc gattgatttc
    25681 cctaagtgaa gcattgtcaa agtatgataa gctaatccac tggcaaatgc atgatggttt
    25741 ctttttgctg ccggaaactc aaaaaattgt ttttgatatt tattaagtag atagcgaaca
    25801 atacgattcc aatgcgcatt ggtgatctca aacaacaatt gattgatttc ttcttccatt
    25861 tcttctttct tcaaaggggc tctttccatg tataaactag gctctcctgg ctcatctacc
    25921 cttgttaagc gcatatgaag aatctttact tgagggtttc cttgataaac ctctctttta
    25981 ccgtttagaa aaacgactgt gccggctgta aatttattga tttcctcctc cgaagcatcc
    26041 cagtatttac catcgatagt acctgaagta tcttggaaag taaaagcaat aaattttttt
    26101 ccgtttttag cgattcttac atctgcactt ttgatcagga caaattgttc aaactgctca
    26161 tcgattacta aatcacgaat ttttttcatt atttgctcct tctaattgtt ttacgatttg
    26221 gttcatctca tggtaatagc ttaccatttc tttatcagaa gaaaaacaaa ttatttgata
    26281 cttttctcca aatttagcta aaagttcagc taattgatac tttcgctgat gatcataatg
    26341 aagccagcca tcatcaatga tgatcgggca tatcgaacgg ttagcttcta atgagaggta
    26401 agcaaatctc atcgccataa tcagctgatc tttcgtacct gtagataact catagatggg
    26461 aaattctgta tatccgtctg ttaaagtcag tgtatcattt ttcagtaata tcttctgata
    26521 atttcctttt gttaaaatac ctaaataatc acctgctgct cttaacaact ggggtaattg
    26581 tctttcactc atctctgttg aaagatcacc taagaatgtc ccggcgattt caagtgctcc
    26641 ccattcctcc agtaattcct gtaattttgc tttttgccgg ctagcttgtt gataaagttc
    26701 gtccaatgtg ccatctcttt gcaactcttc tacttgaagt tggagtcgtt gccgattttc
    26761 acttgcttct ttttcttctt gctggagttg ggattgcttt tctttcagtt ggcgcagtct
    26821 tacagataat ttctcttttg tcagctcttc aggaaatagt ggagtaagca tttccgataa
    26881 ttcattgtat cttttcatct gctgttcggc ttgtttggct ttttgtaaaa agacaggtac
    26941 ttccgaagga taagataagc ctgcttgagt caattgttcg ctgtattctt gtatccatac
    27001 tttttgtttc tttttcaatt gattgatttc ttgcttcaat aaagtatttt gctgatagct
    27061 tctggcaaat ttcatctgtt ccatctcttg tataaaacgg gaaagcaata ccattttttc
    27121 tgaaattgtc ttatcttgta tcggtaacca ttctttaaca aactcaaatt tttggtcgat
    27181 ttgtcgtagc ttttcttgta tttcctgttc tcttttatgt ttccgctcaa atacgccata
    27241 taatttctga taatctatga cttcctgtcc atattctttc atgagtttga gcgtatccat
    27301 ctttcctaag tgccgatgat ccgcaaaacg atatacttct tgctgaagaa tctgtttttc
    27361 ttctccagtt ctcttttgtt tttcttctgc ttcagctaat tgagctaagg ctagatcaag
    27421 ttgtcctagt ttttcttgcc acattccttt tatctcagag aaatcatttt tagttttaat
    27481 ttttggttgc cttttgtaga agaaatagcc aatcatgcct gcaccaatta gtaaaaggat
    27541 cactttcaag ggcattggta caaatatacc tgcaatgatt attgctccgc cagccatcag
    27601 catatacggt ttagatgaag agactggtgc tatctctgac tgattttgta ataatgctgg
    27661 ataggtctct tccaagtcat tcacttctgc ttcaatcatc tcttgctgtt ctttagctat
    27721 ttggagacgc acagaaatct ggctttctag atcagcaatc cttctttctt cagccagaag
    27781 atgcttccat tcttcttcat ataaaaattc ttccggtaac ggatttttct gccaatgcca
    27841 cctttgttcc aaaatcttca attctgaatt tgtttctcta gtctcaattt gtaatctttg
    27901 ccattcttcg tttaattgtt ccgctgtaaa ttgaagttgc tggagatctt ttagttcctg
    27961 ctcctgctct aaataaaaat aatatctggc tgactgctga tccatcccgc tatgcttttc
    28021 cagtgttgct tctaattctt ccaaacgctc atttgtttgc tgataccgtt tggagaaaga
    28081 ctccagatct aaaagaagtt gctcatcagg aagacctgta gtgctgtttt ttttgagaga
    28141 ttgccattct tcatataaag aaaaattaag ttcttgctgt ctggctaatg aaaattgttt
    28201 gttcgcctct tttaattgtg ccaataactg ctgctgttgc gactcgtatt cctgttcttg
    28261 ttggatcaac ttgccaaaat aagcttcctg ttcttgtttt tgatgaattt tttcttgcag
    28321 ctctttccat tcatttaatt tttgattgat tagtagtttt tggccttttt tcttgaataa
    28381 ttgttgtgct ttctgataat attcttgccg cttttggaat acttgagaac tgcccgtgat
    28441 gcctaaagaa atcagcgcat catgtagctc tttttctctc aaatgatcta gttccatcaa
    28501 ctgctcttgc tggaaagtaa atacctgctg gaataactct ttcgtcaaag gtgcgatcag
    28561 tttttctagt aactcatcac ttcccacttg atcccccagc cacaccttcg attttccgcg
    28621 attttgctgc ttgtagcgct cgacagcaaa ttcaccatat acaggatgtt taagccatat
    28681 tttgccgcca taggctgagc cgtcttttgg tgtataatcc ttttttttac ggccttttga
    28741 agggaaacca aataatattg cttgaataaa ttgataaatc gttgattttc ctgcttcgtt
    28801 tcccccatag atcagctgat tgcctgaata aaagtcaaaa cttttttgac gccattttcc
    28861 aaaagcagca atctcgatcc ttaaaatctt cattcctgat cctcctcaaa taaaaaatct
    28921 tgattaagca gctgcttggc tttttcaagt gtttcttctt gatattccgg cagttcgctc
    28981 aatattctag ccgcttcttg atgactatat acttcattta aaatttgttg gaaatcttga
    29041 ggtgtctgat agtattgaaa taactgttcc atcaatttag cagaagcagc aagtgggatc
    29101 ttcgtataaa aagtattctc tatgagagaa atacgccaaa taaagaaatc atttatccta
    29161 tctgagaatt cctctaacaa atagtctaat agctctcctg attgtatccg ttccaaaaca
    29221 tctgtattga gatggtcata atcttttaat tttatctcaa ttaaactaaa tccatcctct
    29281 acttttgaaa gctgctgacg aatgtgaaca atgacctctt ttgtcgttct tgctttcctc
    29341 aatgatattt cctttgtctt ccaatagacc tctgctactt taatcggatg tatttggcaa
    29401 cttcctttac ttaattcaac tagtagaata gatgtagaag cttgttcctt tttagtatga
    29461 ccttgaggcg cacctggata aacaattgtt tgcttttcat ttaagaccgt tggcacatgg
    29521 atatgcccta aagcccaata atcgtatccc ttttcttgca tctttgaggg ttggaaagga
    29581 gcatagtttc ctttttgaga gacgccaggt tccccgtggt acaacccaat atggtaatct
    29641 gtgagttctc tagaaggaaa ttccatcact ttgtcttttt gaatccacgg ttgacgataa
    29701 ctaaatccac tgagagagac agtttctcca ctttttatcg ttattttttt tgtctctacc
    29761 gtttcggatg taaataaatg gacattttta ggaaaggaga accaataccg ctctttttga
    29821 tagaaatcat gatttccgaa tattataaat acaggtatat ggttcttttc taaccgtttc
    29881 atctgttctg aaaaatgttt ctgtattttt aatgaaggac gattttgatg aaaattatct
    29941 cctgcaagta aaacaaaatc aacgttattt attattgcct gttcaatgat atttgataaa
    30001 acggtcagat tcgtcttcaa tagtttttcc tgtacagttt tatcaagagt tgtcagtcct
    30061 tcaaatgacc gatccatatg taaatctgcc gcatggataa atttcaccat taaaaatttc
    30121 ctcctttttt tcttttatca taccattttc aatgtttttt ttcatcaata accgaaaatt
    30181 tgttcgtatt atgcaaagaa attacgataa atggccgact tcaaaaaata agtttattcg
    30241 aaaaaaagat tgtgacatga tttttgtcac aatcctaaat atctatgtta tattcgcttc
    30301 gtttgacact gaagaagtac tatttgtact ggaatttatg ctccattttt ccgtatttag
    30361 aattctatgt tctatactac cttaattagt ttatatggta agaattcttt caaatgcttg
    30421 agatactccg tctttatcat ttgaaacagt gacataatca gcttttttca tgatttcttg
    30481 atgactattt cccattgcaa aactaatatc tgcactttca aacatagata agtcatttaa
    30541 actatctccg atcgcgattc tcaaaggttt ctttaaattg tagattgatt ccaaacgatc
    30601 aaacaccaca cctttagata cattttgagg tacgatttca atatttacag gtgccgattc
    30661 agtaacagac acatttagca tctttttcaa atggttaaat atattagctt tcaattgacg
    30721 attaggaata aaaataaaaa atttgtaaat gctgatagca tccttttcta
//
LOCUS       DADVXB010000018        30622 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.018, whole genome shotgun sequence.
ACCESSION   DADVXB010000018 DADVXB010000000
VERSION     DADVXB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.018"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            147..1016
                     /locus_tag="KB902_000624"
     CDS             147..1016
                     /locus_tag="KB902_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBB6807475.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="KB902_000625"
     CDS             1225..2250
                     /locus_tag="KB902_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6807476.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="KB902_000626"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="KB902_000626"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBB6807477.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="KB902_000627"
     CDS             3333..5036
                     /locus_tag="KB902_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6807478.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="KB902_000628"
     CDS             5038..7071
                     /locus_tag="KB902_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6807479.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="KB902_000629"
     CDS             7082..7522
                     /locus_tag="KB902_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6807480.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="KB902_000630"
     CDS             complement(7722..8849)
                     /locus_tag="KB902_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807481.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="KB902_000631"
     CDS             complement(8852..9529)
                     /locus_tag="KB902_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807482.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="KB902_000632"
     CDS             9793..11559
                     /locus_tag="KB902_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBB6807483.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="KB902_000633"
     CDS             11574..12011
                     /locus_tag="KB902_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6807484.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="KB902_000634"
     CDS             12024..13175
                     /locus_tag="KB902_000634"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBB6807485.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="KB902_000635"
     CDS             complement(13237..13935)
                     /locus_tag="KB902_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBB6807486.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="KB902_000636"
     CDS             complement(13928..15280)
                     /locus_tag="KB902_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBB6807487.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="KB902_000637"
     CDS             complement(15503..16903)
                     /locus_tag="KB902_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6807488.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="KB902_000638"
     CDS             17064..17801
                     /locus_tag="KB902_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBB6807489.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="KB902_000639"
     CDS             17926..18405
                     /locus_tag="KB902_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBB6807490.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="KB902_000640"
     CDS             18402..19169
                     /locus_tag="KB902_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807491.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="KB902_000641"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="KB902_000641"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6807492.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="KB902_000642"
     CDS             complement(20072..20674)
                     /locus_tag="KB902_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6807493.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="KB902_000643"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="KB902_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="KB902_000644"
     CDS             21355..21939
                     /locus_tag="KB902_000644"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6807494.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="KB902_000645"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="KB902_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBB6807495.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="KB902_000646"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="KB902_000646"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBB6807496.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="KB902_000647"
     CDS             23840..24019
                     /locus_tag="KB902_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807497.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="KB902_000648"
     CDS             24041..25066
                     /locus_tag="KB902_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBB6807498.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25241..26485
                     /locus_tag="KB902_000649"
     CDS             25241..26485
                     /locus_tag="KB902_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBB6807499.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26638..27585
                     /locus_tag="KB902_000650"
     CDS             26638..27585
                     /locus_tag="KB902_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6807500.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27719..28348
                     /gene="upp"
                     /locus_tag="KB902_000651"
     CDS             27719..28348
                     /gene="upp"
                     /locus_tag="KB902_000651"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBB6807501.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28494..28730)
                     /locus_tag="KB902_000652"
                     /pseudo
     CDS             complement(28494..28730)
                     /locus_tag="KB902_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28851..28923
                     /locus_tag="KB902_000653"
     tRNA            28851..28923
                     /locus_tag="KB902_000653"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28884..28886,aa:Thr,seq:cgt)
     gene            complement(29042..29680)
                     /locus_tag="KB902_000654"
     CDS             complement(29042..29680)
                     /locus_tag="KB902_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6807502.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29803..30435)
                     /locus_tag="KB902_000655"
     CDS             complement(29803..30435)
                     /locus_tag="KB902_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6807503.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT        10427 a         5381 c         6179 g         8635 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt
    25261 tgaccctgat ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga
    25321 gctgattgcc tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt
    25381 gacaaataaa tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt
    25441 cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc
    25501 gaacgtccag cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga
    25561 accaggggac acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc
    25621 accagtcaac ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac
    25681 agaagttatt gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat
    25741 cgtagcaggt gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc
    25801 agatgaagta ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc
    25861 aggacttcat cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac
    25921 attgcgtggc cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat
    25981 aaatagtgcg gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa
    26041 agcagtagca ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat
    26101 cgccaatgca aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc
    26161 aggggcgaca gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa
    26221 agaagcagag agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt
    26281 tgaaacacta agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac
    26341 tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca
    26401 agcaaaagat gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga
    26461 aaaatttccg ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa
    26521 tgttgggctt ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct
    26581 ctctagtata tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg
    26641 actgatcgta tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat
    26701 ccgcgtatct atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa
    26761 tcacctgtga acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg
    26821 ggaaaactca atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt
    26881 ttttatattc atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc
    26941 agagaacttg cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca
    27001 gaagcaaaat atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa
    27061 ttagccaagt caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt
    27121 ggtaacatgg ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc
    27181 aagcaattgc tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa
    27241 ttcggagaaa actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg
    27301 acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa
    27361 ctaaatgatc ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa
    27421 ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc
    27481 caaggaatca tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt
    27541 gcagcaatgg cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc
    27601 aggaaaactt cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa
    27661 tcacttgatt ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat
    27721 gggcaaattt caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga
    27781 caaaaactgc ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc
    27841 atatgaagta tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga
    27901 aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg
    27961 tattggaatg gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg
    28021 tctttatcga gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga
    28081 cattgatgca cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat
    28141 catggcaatc gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt
    28201 agcagcacct gagggagtaa aagctttgca agaagcgcat cctgatattg acatctatac
    28261 agcttctcta gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc
    28321 gggtgaccgt ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt
    28381 gtcacatcct tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc
    28441 gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atcttttttt
    28501 agttctttgt agttaacgat tactacaccc ttactttgcg tcatcaagtt cgcattttct
    28561 gcagtttcat caatctcaac aacagcggaa tttttcaatt gctttgaaat cgttccagtt
    28621 tgcgacttgc cgtgaattgt gaacattacg tgagtattga tcttgaattt ttcaccaatt
    28681 tccgatggta cgatagttgt atcaaatttt ccaaaagttg ccattttcat aaaacctgcc
    28741 tttcacatca attataccac gttttatgaa aaatatcatg aaattaaact aattttccat
    28801 cggactcttt acaatcagcc aaatagagta tataatttct tttggataag gccagcttag
    28861 ctcagttggt agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc cctatagctg
    28921 gcattaaaag agaagacaga tatatcaagg atttttaatc cattgataca tctgtctttt
    28981 tgtttaaagg aaataaagta tgctttctta gcaatagagc atgtattatt tctataaaaa
    29041 tttaggagaa taaaacgact agcaatatag ctgtgaaatc aaatatcaca tgaactgccc
    29101 aacttgtaat gatcgagttg cttttaatgg cagcttggtt gaataacaat cttgccaccc
    29161 cttgtatcaa aaggatgtgt gctacagtgt gtaaaatatt tccattatca taagtactgt
    29221 aatggataaa tccaaagatg attgctgaca agaaactagc gacaggaatg ctgaacttac
    29281 tagaaaaaat agcgagaaaa tacactgaga acaattcttc tccaagtatc atgataggca
    29341 aaataataaa taataacggg ctgaaagcct catttattgg attgcctgtt aaaccccatt
    29401 tcaaaatttg ttgcaaaaat accgagactg cggcactgat tactacattg ataaaaaaat
    29461 atttggctat atttttgaca ggagcgacag gtttcgagaa catttttttc gtatcttttt
    29521 taccaaaaac aagtgtaaat gctataaatc cagtgatagt taaagaaaaa atgctaataa
    29581 tggatggcgc aaatagcaac cctaacaaac cgagtacaac gacaatagtg cccaatatcc
    29641 cttttttaag ttctattttt tttcctaaaa tgttattcat gataataact cctactattc
    29701 agtttttgaa gatagagtca gtatacatga agagttaaaa taggcaatgt ttttttatgg
    29761 atatttgtat tgctaaaaat ttatcttata tattcatttt gattatacta cttttatttg
    29821 taaaaatttt ctagcaaaac caagtgcttg caactgatta agcgtacaat tttttagatg
    29881 ttccgagcgt acttcaatca tttcaaagga gttgctactt aaatcgatat tttttaaatc
    29941 agtatcaaaa aagctagcat tttctaaatc attagtagaa aacattattt tagtgaggga
    30001 acagtctaca aaatctgcgc ttgataagac agagtgctca aaggtacttt cttttatgtt
    30061 tgaaccagat aaatttacat agtccatttt acaattctcg aataacgtgt tcccaatata
    30121 actttccatc aatttagtac ctgttaattt acaattgaca aatttcacgc gatgcaacat
    30181 gctttttgtc aatatacagc ctgaaaaatc acagttttcg aatatacagt cggtaatctc
    30241 cattctttga aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat
    30301 tggatggcag attatttggt tttcgatgac ctctttttgt gaaaggatat tatacagttc
    30361 aaaatcttcg ttttcataga tatgaaaaaa ggatccttta ttcaagcttg cttcattaac
    30421 tttaggaaaa atcatattta attacctcca ttttcataaa gtcatattaa caaaagctaa
    30481 accaacttac attagcagaa aatgagatag gttttcgcct ttttcgataa cgatagtgtc
    30541 gctatctctt gaaacgttct tagaattgcc ctgagagaca caaattaggc gtaattctaa
    30601 taaaaatctt agaataaaaa tt
//
LOCUS       DADVXB010000019        29377 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.019, whole genome shotgun sequence.
ACCESSION   DADVXB010000019 DADVXB010000000
VERSION     DADVXB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.019"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            106..1527
                     /gene="arcD"
                     /locus_tag="KB902_000656"
     CDS             106..1527
                     /gene="arcD"
                     /locus_tag="KB902_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBB6807504.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            1541..2659
                     /locus_tag="KB902_000657"
     CDS             1541..2659
                     /locus_tag="KB902_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBB6807505.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(2719..4011)
                     /locus_tag="KB902_000658"
     CDS             complement(2719..4011)
                     /locus_tag="KB902_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6807506.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            4143..4721
                     /locus_tag="KB902_000659"
     CDS             4143..4721
                     /locus_tag="KB902_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6807507.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            4850..5227
                     /locus_tag="KB902_000660"
     CDS             4850..5227
                     /locus_tag="KB902_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBB6807508.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            5160..7232
                     /locus_tag="KB902_000661"
     CDS             5160..7232
                     /locus_tag="KB902_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6807509.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(7443..8390)
                     /locus_tag="KB902_000662"
     CDS             complement(7443..8390)
                     /locus_tag="KB902_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6807510.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            8636..9100
                     /locus_tag="KB902_000663"
     CDS             8636..9100
                     /locus_tag="KB902_000663"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBB6807511.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(9162..10205)
                     /locus_tag="KB902_000664"
     CDS             complement(9162..10205)
                     /locus_tag="KB902_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBB6807512.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(10582..11547)
                     /locus_tag="KB902_000665"
     CDS             complement(10582..11547)
                     /locus_tag="KB902_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBB6807513.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            11781..12626
                     /locus_tag="KB902_000666"
     CDS             11781..12626
                     /locus_tag="KB902_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6807514.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            12817..14004
                     /locus_tag="KB902_000667"
     CDS             12817..14004
                     /locus_tag="KB902_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6807515.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            14010..14366
                     /locus_tag="KB902_000668"
     CDS             14010..14366
                     /locus_tag="KB902_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBB6807516.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            14368..14706
                     /locus_tag="KB902_000669"
     CDS             14368..14706
                     /locus_tag="KB902_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBB6807517.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    14782..15038
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15101..16135
                     /locus_tag="KB902_000670"
     CDS             15101..16135
                     /locus_tag="KB902_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807518.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            16128..16814
                     /locus_tag="KB902_000671"
     CDS             16128..16814
                     /locus_tag="KB902_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807519.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            16838..17686
                     /locus_tag="KB902_000672"
     CDS             16838..17686
                     /locus_tag="KB902_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6807520.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            17883..18656
                     /gene="sufC"
                     /locus_tag="KB902_000673"
     CDS             17883..18656
                     /gene="sufC"
                     /locus_tag="KB902_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBB6807521.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            18669..19955
                     /gene="sufD"
                     /locus_tag="KB902_000674"
     CDS             18669..19955
                     /gene="sufD"
                     /locus_tag="KB902_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBB6807522.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGMIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            19952..21187
                     /locus_tag="KB902_000675"
     CDS             19952..21187
                     /locus_tag="KB902_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6807523.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            21174..21644
                     /locus_tag="KB902_000676"
     CDS             21174..21644
                     /locus_tag="KB902_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBB6807524.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            21649..23040
                     /gene="sufB"
                     /locus_tag="KB902_000677"
     CDS             21649..23040
                     /gene="sufB"
                     /locus_tag="KB902_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBB6807525.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(23135..24277)
                     /locus_tag="KB902_000678"
     CDS             complement(23135..24277)
                     /locus_tag="KB902_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6807526.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(24316..25050)
                     /locus_tag="KB902_000679"
     CDS             complement(24316..25050)
                     /locus_tag="KB902_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6807527.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            25285..25560
                     /locus_tag="KB902_000680"
                     /pseudo
     CDS             25285..25560
                     /locus_tag="KB902_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25658..27655
                     /locus_tag="KB902_000681"
     CDS             25658..27655
                     /locus_tag="KB902_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807528.1"
                     /translation="METPIIIIPINVDKERLLEKPVIEDEKKRIRKRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNKSEEFLETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKALSINLVHNSAFAIQKSIRYSENLEKFKIVFLLKEAITDYSKMIAVYEYLKKI
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHDDHNPSASIFTSKTGHSIFYCHSSNCGISENFIGVVMLILEKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMEDKLFRTINNYLEEMRRVYDALLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKWNKLLSFMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLKKVHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNFRSELSKEKQLILDEAHEVLQDLSWQGTYLMTEKELINTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELIASGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(27731..28066)
                     /locus_tag="KB902_000682"
     CDS             complement(27731..28066)
                     /locus_tag="KB902_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6807529.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            28192..28407
                     /locus_tag="KB902_000683"
     CDS             28192..28407
                     /locus_tag="KB902_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6807530.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            28444..28806
                     /locus_tag="KB902_000684"
     CDS             28444..28806
                     /locus_tag="KB902_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBB6807531.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            28852..29178
                     /locus_tag="KB902_000685"
     CDS             28852..29178
                     /locus_tag="KB902_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807532.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
BASE COUNT         9754 a         5217 c         6117 g         8289 t
ORIGIN      
        1 caataatatg aataaagttg ctttttgtta agcaagagca gttgcaaaat agaagggaat
       61 cttttgcaag tgatttgttc aattttataa gtgagggtga tggaaatgga aaagaaatcg
      121 acgggtatta gcaaatgggg actggttgct ctggttgtca gttcgtcaat cggaagcggt
      181 gtgtttggga tcacaagtga tctggctagt tctgcagctc cagggccagc gatcctttca
      241 tggataatcg ttgggattgg tattttagct ttggtattat cgctgaatca tttaggagaa
      301 aagcgtccag atctagatgg tggtattttc ggttacgcgg aagcttcatt tggtaaatta
      361 ggtggcttca tcagtggttg gggttactgg ttgtctgcgt ggctgggaaa tgttgctttt
      421 gcaacgatgc tgatgagcgc catgggagaa tttttcccga tattcaaagg tggacaaaat
      481 gttccttcta ttttatttgc aagtattttt atttggggtc tgactttatt agtaaacaat
      541 ggagttgaag gagcgagcgt catcaataca atcgtgacga tctgtaaatt agtgccatta
      601 ttcctatttt taatatttgt atttatcgca tttaaagtga atatattcac tgctgatttt
      661 tggggtaacg tatctgataa tctagtgaat ggaacagggc agcaaggaac gatctggttg
      721 cagattaaag gttgtttgat ggttatgatg tgggtctttg tagggatcga aggcgcaagt
      781 gttttagcca accgcgcgaa gaaacgttca gaagcccagc aagcatcgat cattggtctg
      841 ctttgtttat tgtttatcta tatccttgct tcgatcttgc catacggcgt cttatctcaa
      901 gaagagttag caactatttc acaacctgct atggcaaata ttttaaaagg aatcgtggga
      961 aattggggag cagcgctgat caatatcggc ttgattattt cgatcattgg ttcttggttg
     1021 tcttggacga tgctcccagc agaaacaacg atgttgatgg ctcgagacgg tctgttgccg
     1081 aaaggttggg gaaaaacgaa taaaaaaaat gccccaactt attcgttagt tgttactgca
     1141 atcttgacta atctattctt attgactttc ttagttactg attatgccta tcaatttgcc
     1201 tattctttat gtacagcggc aattttgatt tgttatctac ttgtcgggat ctatcaagtc
     1261 cagttttctt taaaagaagg aatcaaaaaa caagtagtga tcggtgggat tgctgtagtt
     1321 tttgaattga tgggcatcat tttagcagga ttttcttatg tccttttatg tagtattgcc
     1381 tatcttcctg gtttttgctt ctactggatc gcttgtcgtg aaaccaaaca tcaaattacg
     1441 ggaaaagaaa aagtaatgat tgggctgatt tgtgtggccg cactgctttc aatcgggttg
     1501 cttgctgtag gctggatcaa gatataaggg ggaaagaaac atgaaaatcg caaatttcgg
     1561 tgtagaagaa tggctaaata aatgggaaaa gaaagcggta tatgatattg cacaaagctc
     1621 gatcgaagca ttgacattag acgaactcgt tggcttagat gggactagcg taagtaaatt
     1681 tttcgaaaaa cgcaaaaacg aaccattgga ctatggctgg atcgaaggat cagatgtttt
     1741 caaacaagaa gtcgcttctc tttatcaaac cgtcgatccg gaaaacatct tacaaacgaa
     1801 tggagcgact ggtgctaatc ttttagctct atacgcgtta gtggaagcag gagaccatgt
     1861 tgtttcgatg cttcctactt atcagcaatt atatgacatc cccaaatctt taggtgccgc
     1921 tgttgacttt gttcatttga aggaagaaga agattggcag tttgatttag aacagctaga
     1981 agccttagtc aaacctgaaa caaaaatcat ctgtttgaat agtgcaaaca atcctacagg
     2041 cacattgcta gatcggaaaa ctttagaaaa aatcgcagaa attgctcgta cagtagatgc
     2101 atatgtattg atagatgaag tatatgcgcc tttaacggat aaaggtgaat tcttgtcgat
     2161 cgtagatgtc tatgaaaaag gtatagcaac caattcccta tccaaaacct actccattcc
     2221 aggtattcgt attggctgga cagctactgg acctgagttg gcagaagttt ttcgaaagta
     2281 tcgagactac acgatgattt gcggcggagt cctgtcagat gatcttgctg tacatgcatt
     2341 gaagaataaa gaaaaaatat tggcgcgaaa caaaaagatc attacagaga accttgtgat
     2401 tttaaaacaa tgggtagcca atgaaccgaa agttgaactt gtcgctccca attacgtctc
     2461 tacttctttc attaaattag ccatcgaaga agatgaccag acattttgta tcaatttatt
     2521 agaagaaaca ggagtactat tagtaccagg aagtgccttt gatttaccga agcatgcccg
     2581 actaggttac tgttgtaaaa aagaaacctt ggaaaaggga ttattcctct tatctgagtt
     2641 cttgaaaaaa caggcctaaa caaaaacact gcaaggacag tctgtgacaa ctgttcaagc
     2701 agtgtttttc atttacgctt attgtctatg agaaggagag tgccctgaag ctatggagac
     2761 tcctgaagct ttttcttctg cagtttcttg ctgatggatc tcttgtgtat tgtgtcgtac
     2821 aagcaagaag ttgaccaaaa caagaagaga agtcgaaaga aagacgccgc gataaccaaa
     2881 tgcactggaa acactggagc cgatcatagg ccctactacg ttaccagttg cttggaaaga
     2941 ttggttataa ctgaagatcc gtccagcagc ttgatgaggc gaatattttg tgatcaatgc
     3001 ttggacagca gggagcagac aagcatcaga gataccaatc aaaaaacgta aggcagctaa
     3061 ttgccaaaca ttcgtgacga atgccattgg gatataaacc agaatcgcaa aacccaaacc
     3121 aatcgcaagt attctttcac tcccaatctt gtcacctaag cgaccaaatc ttggagcggc
     3181 tatcaaagtg gcaatcccag gtatcgaagc aatgattccg ctgatcaacg taacattccc
     3241 atgtccatgc agcaattggc gaatgtacag actgatgatt ggactaatgg aattgttgga
     3301 tgcttggatg atcatcgttg tgacgaacat accgatgacg acgtgtggat atttcaagtc
     3361 tttgaaaatc tgtttggcag aaaccatgtt ttcttttttc actgggacaa atttttcatg
     3421 gacgaaaaac agactcaaca agaagacgaa aaataagatg atccctgtaa tgaaaaaggt
     3481 agggcgatag ccaaacgctg aagcagagat cccgccaaga agcggtccaa gtaatgttcc
     3541 tgtaacagaa ccagttgcta aggttccaag aacttgacca cttttttctt ttggcgtccc
     3601 agttgcgaca agggcagtgg cattactgat ataaccagaa aaaatccctt gaagcagacg
     3661 caatgcgact aattgataca cactagtcac gcaacccatc aaagaaatga cgattgccat
     3721 tcctaatgaa gcacgcaaca gcatcaattt tcttcctttt tggtcggcta attttcccca
     3781 ccaaggagag ataagcgtag tcaccaagaa agtagatgaa aaagtcaatc cgctccaaaa
     3841 gttcaattgt gacgtactat aattacctaa cgtatctatg taaagtgaca taaaaggcat
     3901 gactaaacta aatccgatac cagccataaa tgttccaaac cataagacaa acaagttttg
     3961 ttcccaagtt tctcttttcc taaataattt ttcctttatt cttgcagcca attagactcc
     4021 ttctttctga aaattttcat ctacagctct ttattataaa ctacaatatg tagtttatca
     4081 atgaaagtct cttttttctc tttctttttc gtggtaaact gaaagagtga aggatttatt
     4141 ttatgagagg aaacatggaa atgaaaaaaa gaaatctgtc tcaagagaaa atcatcgact
     4201 gctttcgaga actagcagaa gagatggatg ttcagcaaat aacctttcag catttagcca
     4261 aacgcttgga tatcaaggct ccctcgctgt ataaccattt caaaaatatt cgtgatgtca
     4321 aaacagcgct aacagcgaaa cttctgcagg aacttaatga ccagctgcga cgggctcttg
     4381 tgggaaaaag tggtcaggaa gcactgcaga tctatgcaga aacttatcga tcctttgctt
     4441 tttcaaatca agcagtgtat gagttactga tcagtgtacc gcataccaat gaagctgttt
     4501 tattagatgg aatccatgaa acgaatcaga tcattttgca gatatttgag gcttttcaat
     4561 taacgaaaga agaaaaagtt catcgaagca gggaacttcg tagtatgatc cacggttatc
     4621 tttccttacg ttttttagga tactttacaa aagaaccaac aatcgatcca gaagacagct
     4681 atttttggat gatcaataac tttatcgcta ctttgcctta aacaatcaga ttcatttgta
     4741 acaattttaa gatgttcatt aaatgaccct tttataagag aaaattcttg caactttctt
     4801 gaaaagtgac taagatgagt ctagaaaagc tgaaagaagg agcacgagta tgtatcaagt
     4861 aattaccatg ttcggggaca atgagccttg gtggtttttt gaagactggg aagaagatat
     4921 tgaagaagaa gaaacattcg agtctttcga agaagcacga caagcgtacg aaaaacaatg
     4981 gaacgaaatc catcaaaatt atgaatatat caatgcaaaa agtaactttc tcagcgcctt
     5041 ttggaatgac ggagatgagc gctggtgtga agagtgtgac gatgatttac agcaatacaa
     5101 gggacttgcg ttgttgaaaa atcatcagcc catcacagta gaaagcagaa aggaatttta
     5161 tgaaacaact aattctagcg gaaaaaccaa gcgttgcgaa agacctaagc aaggtgcttg
     5221 gtgctaatca aaagcacaaa aattattatg aaggacccaa ggtgatcgtt acttgggccc
     5281 ttggtcattt attaggattg aaaatgccgg aagatctgaa taaggaatgg cagagctggc
     5341 aaatggacac gttgccaatg atccctaaaa aactaggaat caaaccactt cctaaaacag
     5401 gacatcaatt aaaagcaatc aagcagctgg ctcagcgaaa agatgtctca gaagcagtca
     5461 ttgcgacaga tgccggaaga gaaggggaac ttgttgctcg ctggatctta gagtatgtgc
     5521 atttcaataa accagtgaag cggttatgga tctcttctca aacagataaa gcaatcaaaa
     5581 ctggattcaa gcaactaaga cctgcgaaag aatatgatgc attgtatgaa tctgctcttg
     5641 cccgggcaaa agcggactgg ctggtaggat tgaatgtgac cagagcctta actgtgaagt
     5701 acgcggataa tttatcagca ggccgtgtgc agacaccgac actagcatta gtgagagacc
     5761 aagaaaagaa aatcgagcag ttccgtccac aaacgtattt cacgatcacg ttgcaagctg
     5821 gaaaagaaca agccaaaatg cttcaaaaaa atcaatttgc tttaaaaaca caagaagaag
     5881 cacaaaaact tgttcaattg atcagtacaa gcaaaggaac tgtcacagaa gtccaagaaa
     5941 aattaaaaac ggaatctgcg ccattgcctt atgatttaac agagatccaa agagaagcca
     6001 atcaacgcta tggctattct gcaaagaaaa cattaagtct tgtacaaagt ttgtatgaga
     6061 cccataagat cgttacttat ccgcgtacag acagcaaata tctgacaaat gacatgaaaa
     6121 gtacgatgaa agaacgattg caagcagtca gcgactttgc tcctgaggtc aagcagtatt
     6181 tgaaaaacgg agccatcgtc caacagacaa aagtattcca agacagtaaa gtgaccgatc
     6241 accatgcact tttgccaact gaaaacagag cacgttatga aaaattaagt aatgaagagc
     6301 gaaaaatcta tcaaatgatt gtctctcgtt ttttaggact gtttgctcaa ccccataaag
     6361 tcagccaaac aaaagttacg gttgaatttg gtaaagaacg attcattttt cggcaaaatc
     6421 gtgtcgtcca agcaggatgg aaaggcgaaa ctgaaactga gacggaaaca gtcaaatggg
     6481 aaaaaggaat gagaatcaat cccgatttcg ccatcaaaaa agaactatct gcaccgccta
     6541 aaccattgtc agaagcaagc ttgcttggtc aaatggaaaa atacagtctg ggaaccccag
     6601 ctacgcgtgc agagattatc gagaaactaa tcaaatctga actgatggaa cgtacccctc
     6661 aaggactgca agtatctcct aaaggtaagc aattattagt attggtaaat ccctctttag
     6721 taacaccaga tttgacagaa agctgggaaa aagaccttga agctattgct gcaggaaaga
     6781 aacaagcagg aaccttcttg aatggaatcg aaaaagaaac aaaacgcttg gtgaatgaga
     6841 tcaaatcaag caaacaagaa tatcaagatt tctcgattac ccaaaagaaa tgcccagaat
     6901 gtggggccaa tctgcgcgag aaaaacacac gtgacggcaa aatctatgtc tgcaccaatt
     6961 cagattgcaa ctaccgcaga agaaaagatc caaaagtctc taatcatcga tgcccgcaat
     7021 gtcaccggaa aatggaaatc atcgaaggta aaaacggtgc ttatttccgt tgtaaatacg
     7081 atggaacgac agaaaaattg cttgataaaa aagagcagaa gaagaaaatg accaaacatg
     7141 aagaacgacg cttgctgaaa aaatatgcac aagcagaaga accagaagaa agcccattag
     7201 cagcagcact aaaagcagca atgaagaagt aataagatat gaaagaggtt gtgatagaag
     7261 tggtcagctt caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa
     7321 tttcggctta tttccgaaga agctacttct ggaacaccat ttattcggaa aaaaggactg
     7381 tgacaagact tttgtcacag tcctttttca tttaaaaaaa tgtttacttc atttgacgta
     7441 tattattggt gaggcttcaa ttcatttggc ttcacttttt ctgtttctct tatgatataa
     7501 acaggacgct gtttcgtttc taagaagatt ttcccaatat atttcccgat gattccaaga
     7561 cataacaatt ggattccacc aatgaacagg aagatcgaga ccatggaagg ccatcctgat
     7621 gtaggatcac caaacaacaa tgcccgcaaa ataatgaaca aaattgcaat accagaaccg
     7681 acacaagaca aagcgccgat aaatgaagca atcgttaacg gtgcatccga gaagttcacg
     7741 ataccatcaa tcgagtagtt gaataatttc cagaaggacc aagatgtttc gccagccaca
     7801 cgttcgcggt tttcataaga aatatattct gttttaaatc cgacccagct aaataatcct
     7861 tttgaaaatc ggttgtattc tgttaattct aggacggcat ccaccatttg acgagtcatc
     7921 aagcggaaat cacgagcgcc atcgaccatt tctgtatcgc tgattttatt gatcaactgg
     7981 tagaattttt tcgcaaagaa actgcgtatc gcaggctcgc cttcacgagt cgaacgccgg
     8041 gtgccgacac aatcgatatc agaagtagtg atccggttga tcatctcagg aagcagttcg
     8101 ggcggatctt gcagatcaac atccatcacg gtcactaaat ctcctgtaga agcttgcaat
     8161 ccagcgtaca gagccgcttc tttcccaaaa tttctggaaa atgagacaaa gcggacataa
     8221 ggataagctg aggctagctt cttgattgct gctaacgtac cgtcttttga tccgtcgtca
     8281 ataaacaaat attcgaactc atgggcacct ttgaattttt caacctcatc aaaaaaaaga
     8341 ggaacagttt tttcttcatt aaaacatggg acaacaattg atactttcat cgtttctatc
     8401 ctttcaatcg tatgtttata tatggtttac attcaaaatt taataaacct taaataacac
     8461 ctttaaaatt tgattttacg taaaagaaca ggtattcttt ttgtaaacta acgtatttag
     8521 tttaccatgt ttcctcggtt tatcaaactt ttaagaacaa tttttattag ttggcaagta
     8581 gttttggata gagaaaaagg aggaagttcc agtctattga ctaggagcaa acaaaatgaa
     8641 aatacacaca cctatcggct ttttatggtt agatgcagat gaatccggat tgactgctgt
     8701 atcttttcag ccaatttcag aaagcgaatc agcgaatcag cgaattttaa cgcgcacaca
     8761 agaacagttt gaagaatatt ttgcgggaaa aagaaaagaa tttgatgttc ctttatctat
     8821 aaagagaggt acgccttttc agcaaaatgt ctggaaagct ttgtcgacca ttccttatgg
     8881 agaaatccga acgtataaag aagtagccgt tgctgttgat agtccgaaag ctgtgcgagc
     8941 gattgggcag gcaaatcgaa ccaatccatt gccaatcgtt attccttgtc atcgagtgat
     9001 cgggcaaaat ggaaaactga caggatatat gggaaacgca atagatgggg ttgaaatcaa
     9061 acgccaattg ttgttgttag aaggatatct gcaaaattaa aaacagttgt gattcggaca
     9121 ttgttccatg cgagaatcac aactgttttt tcatgttcat tctaaacttt gatcagccaa
     9181 ataaatagta aagccatcac tgtttggaga agcccgacag ctaatccata agataagaag
     9241 cgtgtacctt ctttcatgaa ttttgcaaag tctaaacgca gaccaattgc cgctaaagca
     9301 gtgatctcaa accagctgct gataaaatgt gccgattggt caataactac aggtaaagaa
     9361 aacaagctgt tgaccaaaca aaagatcaca aaccctaata cataccaagg aagcggtaat
     9421 tttcgttttt tctgcgtatc agttggcgtt tcaaacagag ctggttgttt cttgtgcatg
     9481 aatttttcaa acagatagac aacaacaacg agcatcataa tacgtagaat cttaaatagc
     9541 atggcgaatt cgacaacaga attgtcaagt aagcttgccc cagcgactac ttgaccaaca
     9601 gattggagtg taccacccaa aagtgcactt ttttcaatga gatttccacc aaacaactgt
     9661 aatccaagaa aagggagagt caacatcatc acagtaccca gtagattgac tagtgtgatg
     9721 atctgtcctt tttcttcctc tttcgcatgg atggaagggg cgattgaagc aatagcagaa
     9781 gaaccacaaa cagcgtttcc tccagccatc atcaaagaag aagtatcgct gaattgcagt
     9841 tttttaccaa tcaagtaagc accgatgata gtgactgaca tttgcagtaa cacaaaaaca
     9901 attcctttta caccaatttg agcaatcgtt tgagctgtga cagttgcacc tagtaaaaaa
     9961 acagagaatt ctaatagttt gctttcagca aattttgtgc cgattgctag aacaggctgt
    10021 ttaaaaaaag tatttcctaa taaaataccc aataaaatag caatagtcgc tccacctaac
    10081 tgtggcagat aaatagcaag aagcctgctg aaggcagcga tggcaaaaga aagcagtaaa
    10141 ccgggtaaga tttcgcggac cgctgaatcc tttacagatt ttattggatg tgacaatgat
    10201 ttcatttgat cggttccttt cgtcaataaa tactaaaagc atactcgaac atagtagcac
    10261 taaaccagta ttttgacaaa agaacaagag gtcgtgacaa aagtcttgta cgacctcttg
    10321 tttcgaataa acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
    10381 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttcttttac
    10441 gacctcttgg taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccagtaca
    10501 aaaacatgaa cagctgtttt tgtttggccg ttcttattac ttgatgcaga acagcttttt
    10561 cacaacctat tgaatcgatt attaagcgat ttttttagaa acaaattttc catgtttgct
    10621 atgttcttta attaagaaac gtacgtaatg agcaagaacg tagaagacaa ctacacttgc
    10681 aaacagacat tccgcaactt ttaagaaatc caatacgcta ctatagatac ctaaactgtt
    10741 gaagtaatga acagtagtaa atatagctgt tgcagagata acaagcggga atgtaaaggc
    10801 tgcatagctt ggataaaaac gaagcttgaa caaacgtgga agcatagaca gcacaacgaa
    10861 atacaatact tgagataaag cgaacaatgc tacgacaaga taaaaattag gttcagcaaa
    10921 gtttttaaga taacctgtta ggcaaagaga accaggtgct gcaacgatcg taatcagcgg
    10981 acgtgtcgga tgagccatat ttcttacgaa aaagacacgt ttgatgatga tcggcaataa
    11041 gaacgcatag cagatcaatg aaatccaaaa gaaaattttt ccaataagtg ggaagaagtt
    11101 cccggcagtt acagtgatga ccccaaatcc aacgtaaatg ataaaccagc ttggataaat
    11161 tgcttcaatt gaaagatcag ctttgataac atggtgataa ttgaaataaa agacaaggat
    11221 cacttggaag ataacagcgc acagccaaat gaatttgaca attggtgcaa tactttcata
    11281 tgaaacaaaa taagtacaaa taaccatgag tgacatcgta aaagttggtg aaacggaggc
    11341 gatgattgga tcatgcaacg tttgtttcgt gtgttcgaat aagataaaca atttaacaaa
    11401 aatgaatatc ataagaatca tagagatacc gccagttaga ttgcctaaag caacatggtg
    11461 atagtcttta aacagatttc caagggaagc taacccaagg atcaacccgc agatcgggat
    11521 cggaataatt ttcaaaaagt tcttcatata taatattctc ctttttattt aatagatttt
    11581 agtaccaaga tgaacgaata cattgtaaaa tgaataggaa tgtatgatta cgagcaagca
    11641 gacagctgat tgtcttcatc taagttacta gttggatcag caactgtttt gttgtacatt
    11701 tctattatag atggtttttt gtatatttaa atcaaatagt ttttatagta attatcataa
    11761 aaagttatgg aagtggtgcc atgtttaagt tattaacgac ttttcgagca gtatatgaaa
    11821 caagaaattt ttccagagca gcagaagtac tgtttttatc tcaaccagca gtctcgaatc
    11881 aaatcaaaca gttggagcgg gaattgaata tcgatctttt tcaacgtaac ggaagaaaag
    11941 agatgcttcc aactaagcaa gccgacttat tatatgaacg gacactggtt ttgttagaag
    12001 aatgggaaga aactcagcaa aaattgctca atgaacaaaa tgaagaagaa gtatgtcgga
    12061 tcgttgcttc ccacaccttt gctgtctatc ttttgcctca gttgatgaaa catctgatca
    12121 aaaggtttcc taaagtgcat tttgagatcg aaatcacgaa ttctcatgaa tcattagaac
    12181 aagtagcgaa acatgaatcc gattttggtt ttatcgaaaa gccattagag acttccggcg
    12241 tacaaagata ctctttgatg gaagaccagc tagtcatcgc tggggaccca aaaagcaaat
    12301 tgtggcttgt aagagaagca aactctggtg tttttcatta cacgcagcgt tattttgaag
    12361 agatgaatat ccaagataag aagatgatcg tgaaaagtaa cgatgtaatt gttgcgttgc
    12421 tgaaggaagg aatcggtcgc tcgattttgt ctaagcgctc tgttccagaa aatgtgccaa
    12481 tgactccgtt gaatttccat cgatattttt atttcatcca acgaaccaat ctggtttctg
    12541 atcagctgct agagattgcc gaagagatcc ttcgatacaa tgaaagcaca gaaacttctc
    12601 acagcgagga gaatctcagc tggtagataa ttgcatgtat caaaaaaagt tctatgatac
    12661 actaaagata agcagtaggc ttttgtactg catttgctca agcaactgca caaacggaaa
    12721 gttaattttt cccaaatgtc tatggaaaga ctttccatta tctaactgga ccgctataat
    12781 aatcagcagt atggttttta agaaaaggga tgaaacatgg aaaaaaaatt aaaagcttcg
    12841 aacgataatc gtattgatta tggcgtgatt ttaccagtct ttctgttatg tttgattggt
    12901 ctgctctcat tatatgtagc acttagccat gatccgaaca atccagcagt cttgaaaggc
    12961 gtagggatgc aagttgtctg gtatttagtt ggagcggcag caatcgttgt catcatgcat
    13021 ttgaattcca aatggatctg gaaactgact ccttaccttt atggtttggg gttagtggta
    13081 atgggactct tgctcaaatt ctatgatcag aatttagctg cttcaacagg gtctaaaaac
    13141 tggtttcgat tcggtgcgtt tactttccag ccagcagagt tgatgaagat tgcgtacatc
    13201 ttgatgatgg cactgatcgt aactaaacat aatacgcaag taaaagaacg gacgatgaaa
    13261 tcggactttt ggctgattgg gaagctcttg atcgtgacaa taccggtttt agcattgatc
    13321 atggcccaag atgactttgg aacgatgctt gtctttcttg cgatctttgg cgggattttc
    13381 ctgatgtctg gaatctcttg gcgcatcatc gcacctgtag taatcttggc agtagtcgtt
    13441 ggagcaggaa cgatcttctt ggttacgact gaaggcggaa gagacttgct ttataaagtt
    13501 ggattcaaat cttatcagtt tgcacgtatt gattcatggc tggacccttt ccatgatacg
    13561 tcaggaatga gttatcagcc ggcccaagga cttttggcaa ttggtaccgg tggcttgttt
    13621 ggtaaaggat tcaacgtaag caatatctat gtgcctgttc gtgagtccga tatgattttt
    13681 accgttatcg gtgaaaactt cggctttatc ggtggtgcat tcgtcatttt cttgtatttt
    13741 attttaatct atcgtatgat tcgggtgtgt ttcgatacga ataatgaatt ttacgcctat
    13801 atcgcaagcg gtttgatcat gatgctgctg ttccatgtct ttgagaatat tggagcaaat
    13861 atcggattac ttcctttaac agggatccca ttgcctttca ttagtcaggg aggatcctcg
    13921 attttaggga acatgatcgg tatcgggttg atattatcga tgagatacca aaatgaagca
    13981 cctgcaagat cttcaaggag gtaagaaaat tgtacacctt ttactggtac ccgaaatgtt
    14041 caacatgcaa aaaagccaaa gcgtggttag accagcatgg cgttagttat caaaccgttg
    14101 atatgatcaa agaagtaccg aaggcctcaa cgattgagac ttggctagaa acgagtcaag
    14161 taccaatccg tcgcctgttc aacacaagcg ggatgaaata tcgggaactt ggactgaaag
    14221 atcaagtagg cgagtttacg gcttcaaaag cgagccaagt cttatcgaca gatggtatgc
    14281 tgatcaagcg accactgatc ttacgagagg accagcttgt tgcaattgga ttcaatgaaa
    14341 aaatttatga aggagaactg atataaaatg gcaggcaagc atttgaagaa aaaggacaac
    14401 ctttggatct tatttaatgg aaaagaatac tgtgttggtt tgacaaatga agcgcaagaa
    14461 gaacttggag acatcacgtt tgccaatctg ccaaaagcag gacaatcgct aaaaaaagat
    14521 gaacctctga tcgaagttga agcggaaaaa gcggtcaatg aatttgccag cccgctaacg
    14581 ggtacagttt cttctgttaa tgataaaatc ggtgaagata tcaatatctt gaatgattca
    14641 gatgaaatga atgcgtggat cttaagtttc aaagatgttg atccaaaaga atttgacgaa
    14701 ttataaaatc agaaaatcac ttgaaaaaag ttgacactga ttcttccagt tgctataatc
    14761 ataagcaatc ctatatgaaa cgagaaagct ttgaaaagaa gagtacatgt cacggacgtt
    14821 tgaagagagc cctgtttgct gaaaatgggt aacgaaaatg agatggaaga tggtcttaga
    14881 gcagagtaag cgagcgtaag caaacttact acgggagtgc ccgttacagc gcgacagtat
    14941 acggaaagaa gctaagtcca agtactggaa gaggctgtta ttgcgaagta acggtaaatc
    15001 aaggtggtaa cacggaagtt caagctttcg tccttttgct taaggcaaga gggcgaaggc
    15061 ttttttgttt gaaaaattat aagagaaaga tgtgaatggc atgtcattaa tccaactaac
    15121 gaatgtcaaa aagacattca atgggaaaaa cggaaacatc caagccgtca atgacgtttc
    15181 actaaacgtt gaaaaagggg atatttatgg aatcgtcggc tattctggcg caggaaaaag
    15241 tacattagtc cgtctcctga atggacttga gcttcccacg agcggcgaag tgatcgtaaa
    15301 cgatcaagat attacaaaat taaaaaacaa agaattacgt acattccgaa agaaaatcgg
    15361 tatgatcttc cagcatttca acctgttatg gtcaagaact gtacttgaaa atatccagct
    15421 gccgctggaa ttagctggcg taccaaagag caaacgtaaa gaacgggcag aagaactgtt
    15481 gcgtttagtc gggttagaag gacgcggaca agcatatcct tcacaacttt ccggcggaca
    15541 gaaacaacgc gtcggtatcg cacgagcatt ggcaaatgat cctgagatcc tgctttgtga
    15601 tgaggctact agcgcattgg acccgcaaac aacagaagaa gtattagact tattgttagc
    15661 gatcaataag aaattgaatt tgaccatcgt cttgatcaca catgaaatga atgtgatccg
    15721 caaaatctgc aacaaagtcg ctgtgatgga gttggggaaa gtcgtagaag aaggagacgt
    15781 attgactgtc ttcagacaac cgaaaaaaga agtaaccaaa cgctttgtac aacaagacat
    15841 cgaaccagaa gctgattcga cagaactatt agctgaactc atcaaagaaa atccaagcgg
    15901 ccgtttggca actttgacct ttagcgaaag aaatgccaac gagccagtca tttcccaagc
    15961 gattcgacgc tataacatcg atgtcaacgt tgtgtatgga aagatcaaac aagtgaaaga
    16021 aggttccttt ggttcattga ctgtcttgat gactggtgaa accaaagaat tagatcaagc
    16081 agaagtgttc atcaaagaac aaggagtagg aattgaggtg atccatcgtg gataaaagct
    16141 tttcagaaac atatctagat tttaaacaaa tcaacccgga aacgatgaat caggctatcc
    16201 ttgatacact atatatgaca ttaatctcaa tggtcttagt gacgatcatc ggattagttt
    16261 tgggattgat cctttactct attggacgca aaaacaaacc gtatgctcga atcatttatg
    16321 gaatcgtatc gatcatcagt aatattttcc ggtcaacgcc atttatgatc ctgatggttt
    16381 tgatcattcc atttactaaa gcaatcgtag gcactatgct aggtgcgcaa gcagccattc
    16441 cagctcttgt tttatccgca gcaccatttt atgcccgtct agtagagatt gcttttcgtg
    16501 aagtcagccc tggtgtactg gaagcagcag atgcaatggg agcaagttac tgggaaatca
    16561 tctggaaggt cttgatacct gaaagtattc ccgcattgat ttctggatta acagttacaa
    16621 cgatctcgat gatcggattt actgcgatgg ccggcgcgat cggcgcaggt ggacttggag
    16681 gtcttgcttg gcaggaaggc taccagcgtg gtaatctaac agtgacattc gttgcgactt
    16741 taattatttt actaatcgta tttatcgttc aaggaatcgg tgatttctta actaagaaaa
    16801 cagacaaaag ataataggat atagggggat gtaggatatg aaaaagaaaa tttttggatt
    16861 tgcagcagcg cttttgctga ctgtaggatt agcagcatgc ggtaacaaca gcgacagcaa
    16921 agattcagca aataaagcag acgacacgac attgaaagtc ggcgcttcac cgacaccgca
    16981 cgcagagatt ttggaacatg tgaaaccatt attgaaagat gaaggaatcg atcttgaaat
    17041 cgtcaaattc gatgactatg tattaccgaa ccaatctttg gaagaaggcg acattgatgc
    17101 caattacttc cagcatattc cttatttgaa caaagaaatc aaagaaaaag gatatgactt
    17161 tgtcaatgcc ggtgctgtcc acatcgaacc aatgggcttg tactctaaaa aagtcaaaga
    17221 tgtttccgaa ttaaaagatg gtgcaacaat cattacttca aattctgaat cagactgggg
    17281 acgcatcatc acaattctac aagatgctgg cttagtcaaa gtcaaagatg gagtagatct
    17341 ggaaacagca acattcgatg atattgaaga aaaccctaag aacttgaagt tcaaccatac
    17401 gatcgaccca tcacttttag cttctacgta ccaaaatgat gaaggtgacc tagttgcaat
    17461 caacgcaaac ttcgcttacg gcgcagggtt gaatccatta gaagatgccg tattgcttga
    17521 aaaggacaac tctccttacg tgaatattat tgcgactcgt aaaggtgatg aagacagtga
    17581 caaaatcaaa aaactgattg aagtgcttca ccgcaaagaa gtccaagaat ggatcacaga
    17641 caaatggggc ggctctgtta aaccagtaaa ggctgatgca aaataaggta tggaacaaaa
    17701 aagatgagaa ataagtctgt aatggcttat ttctcatctt ttttatacct attctaattt
    17761 agaaatcaaa attgtttaat aataaataaa agatatttga ttttagtaag gaaggtcatt
    17821 gcgcttcatt ctcaattagt ctaaaatgag tgagaacgaa agagaatttg ggggtataat
    17881 gcatgtctgt cttagaaata aaaaatctac atgtgtcgat cgaggaaaaa gaaatcctta
    17941 aaggcgtaaa cctaacaatg aaaaccggag aaatccatgc catcatggga cctaacggca
    18001 caggaaaatc taccttatct gccgctatca tgggcaatcc aaactatgaa gtaacagaag
    18061 gcgaaatttt gtttgacggg aaaaatgttt tagacttgga agtagatgaa cgtgcgcgac
    18121 ttggcttatt tttagctatg caatatccaa gtgagatacc aggtatcacg aatgcggaat
    18181 tcatgcgtgc agcgatcaat gcgaaacgtg atgaaaacga caaaatttct gttatggcat
    18241 ttttgaaaaa gttagatgaa aaaatggctt tactaaatat gccagaagaa atggctgaac
    18301 gttatctgaa cgaaggtttt tctggcggag aaaagaaacg gaatgagatc ctgcaattgt
    18361 tgatgttaga acctacattt gcaattttag acgaaatcga ttcaggtctg gatatcgatg
    18421 ctttgaaagt cgttgctaaa ggagtaaatg aaatgcgcgg agacaatttc ggtgcattga
    18481 tcatcaccca ctatcaacga ttattgaact atatcacacc tgatgtcgtt cacatcatga
    18541 tggaaggccg agtagtcatg acagggaatg ctgacctagc taaacgtctg gaagcagaag
    18601 gctacgctgg tatcagtaaa gaattaggaa tcgactataa agaagaagaa gcgtaagggg
    18661 gagcaagaat gaaagaaaaa aactggctcg attatcttga cgcggtaaat gatttttctt
    18721 taagtaaagg cgaacctgat tggatgagaa ccttccgtca agacgcacta gcgaaagcag
    18781 atgaactgcc attgccgcat atcgatcggg tgaaattcca tcgctggtcg ttatttgatg
    18841 tgaaagaaac acaaaccatc agtgaaacag gcatgattcc ggcatttgat gcaatgaaag
    18901 acaatcctgt gcttgtccaa caaggttcat ggacgatttt tgaacaactg cctgtggaat
    18961 tagcagaaaa aggagtcatt tttaccgact tgttcactgc aatgatcgaa tatccagaac
    19021 tagtccaaga atattatatg aaaaaagcag taaacatgaa cgaagaccaa ttgactgcac
    19081 tccatgtagc ttttatgaac agcggtattt tcctgtatgt gcctaaaaat gtcgtgatcg
    19141 atgaaccact cgagtcctta ttcattcaag atggcgcatc cgatgagcac ttcttcaagc
    19201 atgtgttgat cgtggcagat gaacatagtg aattttctta tctggaacgt ttccagacaa
    19261 ccaaagaaca agtagcaaaa tcatcaggta atatcatcgt ggaagtcatc gctaaagctg
    19321 gttcaaaaat caaatattca gccgtagatc aattaggaga aaatattact tcttatatga
    19381 atcgccgtgg gcacatttta cgagatgctt ctgtcgactg ggcaattggt gtcatgaatg
    19441 acggtcatgt gatcgctgac tttgactcag atttagcagg agaaggtgca cacgcagaag
    19501 tcaaaatcgt ggcaatcagc tcgggcagac aaatccaagg aatcgataca cgagtaacca
    19561 ataaagcccc tcatacgatc gggcatattt tgcaacacgg agtgatccga gaaaaaggaa
    19621 cattgacctt taatggtatc ggccacatct tgaaaggggc aaaaggtgca gatgcccaac
    19681 aagaaagtcg tgtcttgatg ctttctgata aagcacgtgg tgatgcgaat cctattcttt
    19741 tgatcgatga aaacgaagta actgctggac atgctgccag tgtaggacga gttgatccag
    19801 aagaaatgta ctatctgatg agtagaggat tgcataaaga agaagcagag cgcttagtga
    19861 ttcgaggatt cctcggttct gtcttaacag caatccctgt agaacaagtt cggaaagaat
    19921 tagtcgaagt aatcgaaggg aagttgaatg gatgatcgat gctaaaaagc tacgcaatga
    19981 ttttcctatc ttatttcaag acgtcaatga tgaaccttta gtttatctgg ataatgcagc
    20041 gacgacccaa aagccaaaac aagtactcca ggcattagcg tactattacg aacacgataa
    20101 cgccaatgtt catcgcggtg tccatacgtt agcagaacgc gcgacccatg attatgaaca
    20161 agcaagagaa aaagtacggg cgttcatcca tgcaaaagaa acagcagaag tgctgtttac
    20221 tcgtggtacg acgacaagct tgaattgggt agccagaacc ttcggcgacc gctatatcaa
    20281 agcaggagac gagatagtgc tctcttacat ggaacatcat tctaatgtta tcccgtggca
    20341 gcagttggca aaacgaacag gtgctgtctt gaaatatatc gaactaacag aagaaggctt
    20401 cctggatatg gaggatgcag cgaaaaagat tacggacaaa accaaaatcg tctccattgc
    20461 tcatgtatcc aatgtcttag gtgtcttcaa tcctgttcaa gaattagctg aacttgtcca
    20521 tgaaaacggc ggggtcatcg tagtagatgg tgctcaatct gccccgcaca tggccattga
    20581 tgtccaagca ctagactgtg atttctttgc tttcagcgga cacaaaatgt gcggaccaac
    20641 aggtattggt gttttatatg gtaaacgaaa atggttagaa gaaatggaac ctgttgaatt
    20701 tggtggcgaa atgatcgatt ttgtcgaatt atacgacagt acatggaaag aactaccttg
    20761 gaaattcgaa gcagggacac caaatatcgc cggcgctatc gcattaggcc atgcaatcga
    20821 ttatttgcaa aaactcggta tggacaatat ccatcgatat gaagaagaac tagccgctta
    20881 tgtgttgcca aaattacaag caattgatgg attgactgtt tatggtccac aagacccgaa
    20941 ttttcggaca ggagtcgttg cattcaattt ggatgggtta catccccatg atgtcgcgac
    21001 agctttagac atggaagggg tagccgtcag agcaggtcat cattgtgcgc aaccgctatt
    21061 gaagtacctt gaagtatcag cgactgctcg cgcgagcttt tatttctaca acacaacgca
    21121 agacgccgac cgtttagttg aagcaatcat ggcaacaaag gagtttttcc aacatgggac
    21181 tatctaaatt agacaattta taccgtcaag tgatcttgga tcattcttcc catccgcatc
    21241 atcgtggaag cttgactgac tcgacaagca agatcgaatt gaacaacccc acatgtggag
    21301 atgtgatcga attgcaagtc gatgtaaaag acggaatcat caaaaatatc gcctttgacg
    21361 gcagtggctg ctccatcagt acggcaagtg cctcgatgat gacagacgcc gtcatcggaa
    21421 aatcaataga agaagcagaa catttaactg tagactttct acagcttgtc caaggaaaag
    21481 aagtcaaaga tcccgaccaa ttaggcgatg ctgctatgct tggtggtgta gctaaatttc
    21541 ccgctcggat caaatgtgcg acacttgcct ggaaagcact aggaaaagca atggaaaacg
    21601 atggtaccgc agctttccat cattaccaca aggaagagga gtgagaacat gggcgtacca
    21661 gaattagaag aatataaatt cgggtttcac gatgatgtcg aaccggtttt cagtacagga
    21721 gaaggcttga cagaagaagt gatccgtgag atgtcaagaa tcaaaggcga accagaatgg
    21781 atgcttgaat tccgtctgaa atctctagaa acatttaaca aaatgccaat gcaaacatgg
    21841 ggccccgacc tttcagacat cgatttcgat gccatcaaat attaccaaaa accaagtgac
    21901 aaacccgctc gtgactggga agacgtacca gaaaaaatca aagatacatt tgaaaagatt
    21961 ggtataccag aagctgaacg agcttatcta gccggtgctt ccgcacaata tgaatcagaa
    22021 gtcgtgtacc ataatatgaa agatgaattc gaaaagttag gaatcgtctt tactgacact
    22081 gactctgctt tgaaagaata ccctgaatta ttcaaagagt acttttcaaa acttgtaccg
    22141 ccaaccgaca acaaattagc agcgctgaat tcagccgtat ggtcaggtgg gacctttatt
    22201 tacgtgccaa aaggcgtcaa agtcgatgtt ccattacaaa cgtacttccg gatcaatgcg
    22261 gaaaacacgg ggcaattcga acgtacgctg atcattgttg acgaaggagc aagcatccac
    22321 tatgtcgaag gttgtacggc acctacttat tcaagtaaca gcctgcatgc cgccatcgta
    22381 gaaatcttta caagaaaaga tgcgtattgc cgttacacaa cgatccaaaa ctggtcagac
    22441 aatgtgtaca acttagtaac caaacgagca aaagcatacg aaggcgcaac cgttgaatgg
    22501 atcgacggaa acctaggtgc aaaaacaacg atgaaatacc caagtgttta cttagatgga
    22561 aaaggtgcac gaggcaccat gctctccatc gcctttgcag gagcaaacca aatccaagat
    22621 acgggtgcaa aaatgatcca caatgcacca aatacatcta gctctatcgt ctctaaatca
    22681 atttcaaaag acggcggaga agtaaactat cgaggacaag taacctttgc caaaaacagt
    22741 gcgggttcga tctctcatat cgaatgtgac acgatcatca tggacgaatg gtcgaaatcc
    22801 gatacgatcc cattcaatga gatccacaac agccaagtct ctttagaaca cgaagccaaa
    22861 gtctcaaaaa tctcagaaga acaactctac tatctgatga gccgaggcct gaccgaatct
    22921 gaagcaactg aaatgatcgt catgggcttt gttgaaccat tcaccaaaga acttccaatg
    22981 gaatatgcag tcgaactcaa tcgattgatc agttatgaga tggaaggcag tgtaggataa
    23041 acttgttata ggagctagaa tccttggtat ataagggttc tagctttttt attttgtcta
    23101 tatactagaa atgaccagct tttgaccagc tcttttactg atgagccatc atatcagcaa
    23161 agtcttgacc tgttttctta ggtgcattat ttgtaatatg tgcatagatg tctaatgtca
    23221 ctttactatt ttcatgccct aatcgttgtt gaactacctt gacagattct cctgcttcta
    23281 ataataaact agcatgtgta tgtctaaacc catgaggtgt aatacgaggc aagttatatt
    23341 ttttcaaaat atatcttaac caatcattaa cagtgtttgg aatgtataga gtgtttttaa
    23401 ctgttgtaaa aacatgttgc tctttagagc tagtattgta tccaagtttt aaatactctt
    23461 ctttttgctg taatttccag ttgttgagga tagaaagagt ctcagtatct aaagagataa
    23521 ctcgtctaga agctcttgtt ttcggagatt gaattataac tttaccaaat tcatctacag
    23581 caagagtttt attgacatgt agttctttat taaacgtgtc tatgtctttc cactgtaaag
    23641 cgagtacttc actctttctc atacctgtgt atgccaataa tctgaagaag gcgtattgtt
    23701 tcatgttacc aaaatcttta aaagcatcca gtaaattatt aagctcctct tttgagtaaa
    23761 atttacgatt tttctcatac tctttttttc gtggaagaag tgttttttcc ataggattat
    23821 tgtcaatata ttgcattgca accccgtagc gtaaaatttg tgcagtctgt tttctcatat
    23881 aatcgtaact ttcatattta ctgtgccatt catctaccac tttttgacaa tatgggacag
    23941 agatattcga tagtttaagc ttaccaaatg ctggaagtat ttgattattt gcgtatctta
    24001 ctgagattgc gattgttgaa gctttaacac tggtacgctg atgagttatc cattcattat
    24061 acaggtcttc aaatgtcata tcaggtgctt tctttttaac accgtataat atttgatgtc
    24121 tgtactcgtc ataatctttt tgagcttctt gtttgctact aaaacctctt ctcgtagtat
    24181 ttattttttc accagttcgt ggatcggtgg caatgtgtcc tttatacatc cacgccactt
    24241 gaccgttttt ctttttgtac tttgatattt ttgccatgaa atcatctcct cttagtttac
    24301 aaggagtact taccactaga tggtatcacc tcccttcatt tttttcttag tgtatttttt
    24361 cccaattgat gaaatcgttt gttttagctt gtttatatta tcaataattt cgtttacagc
    24421 ttcttcggga taattcatgt cttccacttg actatgtatc ccttcatcta tcatttcttc
    24481 tagttgttcc tctatactgc tagtgagcag aagaatgtta ttgtcaaatt cttctataat
    24541 agcattgatg aataattctt ctatttttaa gatattgaaa agactaattt tttcattttt
    24601 aactttatta caagtcttgt tagcaataaa ttcttgcatc tctggttcta atttggaata
    24661 tctatccagc catgtatcta aattagagtg tactggtggg aactgttgac gaagatgctg
    24721 gaacaggttt ttatctggaa atgttatacc atctagtaca atgctatctc tataaagaat
    24781 aattcccaaa atatattctt ctacattgcc acaaactaac tcctctatac tcatatttcc
    24841 caaatcagca attcgggata atcgctctgg tattggtaaa taggttccct tttcccattc
    24901 gtagatagtt tttttgtcaa tcaattgacc attgttaatc ataagaccaa atgctggttg
    24961 tgttaatttt ttactctttc ttatagcttt tatttttgtt ccgagtatct tttttcgttc
    25021 taaataattt attggtggac gctttatcat attgaccaca cctcctaaaa ttagtatacc
    25081 tcaaaaaggg ggtgttgtaa ataaattcac acaacatatt gacacccctt ttgtatcgag
    25141 gtattatgtg tatgtcgatg aactgataat cattttttat ttgattaatc ggttaataac
    25201 aacaaaatac ttttattttg atcaaataat acgaagatga ttcttagaaa atttgttcaa
    25261 gtaatcacga aaggaggggg aaatatgtct ctacaaatca ttgatagcat tgtttctata
    25321 caagttgaac aacaagtgaa agagataatt acagtgctaa agcctatgct agaagacatt
    25381 atttctggtg ttactctaga gtatatggac tatcagcagg caagtgaata tctaggtgta
    25441 tcagtaggaa cgattagaaa atatgtttct taatacgggt tacctgttat aaaaattgat
    25501 acggtcatta gattcaaaaa atctgatatt gatagtttca tggaacagta taaaggttga
    25561 gtaaacaaat aagactaaaa catatagtaa taaagagttt gtgtttatta tctgtatgtt
    25621 ttagtcttta acagaatttt ataaggagga aacacaaatg gaaacaccaa taattattat
    25681 tccaattaat gtagataaag aaagactatt agagaaacca gttatagagg atgaaaaaaa
    25741 gagaatacga aaaagatgtt tagataacta cagagaagtt acaagagatg agtttgtaga
    25801 gatactaaat tcatcacaat catttattcc aagtaagaca aagaataaag gcaacaaaag
    25861 tgaagagttt ttagaaacta gagtaattat tctggatgtc gataacactg ttaaagatga
    25921 gaaggggaag gtagtagatt taagtaaaga tgatagtaga tacttaagca tagaaaaggc
    25981 tttatctatc aatttagttc ataattctgc gtttgcgata caaaaaagta ttcggtactc
    26041 tgaaaatcta gaaaaattca agattgtctt tctattaaaa gaagcaatta ctgactatag
    26101 taaaatgatt gctgtttacg aatacttgaa aaaaatcata cccgggtgtg atgacaatgt
    26161 aaatgcttcg aatagaatgt tttttggagg atataagtca gatgcagtga taataattaa
    26221 tgaagacaac atgttagata ttactgagct tccgattgat tttaccatga catgttctaa
    26281 aaattgtcaa agtgattcag ggagagagta tgaactagtc aatgaaactg attttgttaa
    26341 gttgataaaa aatgacgaca aagaagaaat gaaacagtgg tttaaagact gcctgtttga
    26401 ttcctccgac atgtctttta atgagattta tgaaagattg ttaaccattg atatgaataa
    26461 attacttaag tcaagtaaaa acttaagatg tctgtttcac gacgaccata atccatctgc
    26521 tagtattttt accagtaaaa ctgggcattc cattttttat tgtcattcca gtaattgtgg
    26581 tatcagtgaa aattttattg gggttgtgat gttaattcta gagaaagata gtcgggtaga
    26641 aacatttaat tggctattag agaatctaga cctgtatcct acacattttc gaaaattgaa
    26701 agaggaatca aaagtacttt ttgacactct tgaatctatg gaagacaagc ttttcaggac
    26761 aataaataat tatctagagg aaatgcgacg tgtctatgat gccttgcttt ctgatgttaa
    26821 tttttttgat gatagtaagg aaagtgtgac ttgtatttta tcaggagaac aactagctaa
    26881 aaaaatgagt tcttactatg gtaaaactta tgacatagat aaatggaata agttactatc
    26941 atttatgaca tttataggat tgataaaaaa attagatgat gaagatgttc ctttgaagat
    27001 gctcgaatac ctaaataggt taaaggaaga gaaagcgtta ggaaacttta atcataagag
    27061 aagcaatgtc tatcgattag acgtttttaa tgcaacttct gtgattcaaa aattgaatga
    27121 agatatcctt ccacttctga aaaaagttca ttttacatat caatattttt cttatgaatg
    27181 ggttaagata tgttttaacg aaaaagaggc taaaagagta tttcctcaaa attttcggtc
    27241 agaactcagc aaggaaaaac aattgatttt agatgaggca catgaagttt tacaggactt
    27301 atcgtggcaa gggacatatc taatgacaga gaaagaactt attaacactg tttgtgaacg
    27361 tctacgtaat gttgggaata acagcgtgga aaatgcttta aaagaaaaca gaggctactt
    27421 tgttaaacaa ggattcactc ttgaacgagc ttctaaggat attaagaaac tatacaatgt
    27481 gaaagcaagc agtagttttt tagtctacct agcaaaagga gcagggatag atgaagtaat
    27541 aaaagaattg atagcatctg gtgttgaatt agttcctctt tatcaattta caagtgtaac
    27601 aagagatgat ggacggagag taaggaagag aaaagaccca attgtattaa actagacagg
    27661 ttatccatag ctcttaatct tatttcatct caatacaccc accgttaaag ttcggtgggt
    27721 tatttatttt tcaatctttc aatagctgat tgcgttcatt ttcttgcctt tttaatagct
    27781 tcatatagtc aattgttcga actgcatctt cagtgctaag agaacgatag agagccaaaa
    27841 actcttcctc ataatctacg acaacattgt ctagaaaatg gcttacaggg gttcctaggg
    27901 ctctagaaag agctgttaag ctatcgaggt taggctctgt tacagaattt tcccatcttg
    27961 ctactgcctg ttgtgtagag aagatttttt cagctaattc tttttgtgtc cacccgagag
    28021 cttttcgctt ttctctaatg acctttgcat attgtttctg tttcattaat acacccccat
    28081 ctcagtatag tacaacaagt tgttgtattt gtaatggtat ttgaagtttt tatattttat
    28141 gagttgaaat acatcatatt gttgtatata ataaaacagg aggggagaat catgaaaaaa
    28201 gtaagtaatc tcagccgata cagaaaagaa aaaggacttt ctcaaacgga gttagcaaaa
    28261 aaaatgaatg ttacacagca atgtgtaagt tcgtggcaaa cagggagaac gattcctaaa
    28321 ccctatcaaa tgaaaatgct ttctgagata ttaagtgtac caataaacga gctgttttct
    28381 gatgtgttta ataaagtaaa cagttaacta ttaagcaatt gaatgatttt aggaggagaa
    28441 gacatgtatt gtagaaaatg tggtaaagaa ataacagatg aaagtaagta ttgccagttt
    28501 tgcggagcat tacaagaaac agatgagaca actggagcag acgaagtaaa gaaaagtact
    28561 gagcagacat ttagtgaaat gaaggaacaa atcgtacatg gacaagagac agggaagctg
    28621 tatttgatta ttggttggat ttctatggta gtatcgttag catttattcc tgttgtattt
    28681 ggtgctgttg ctgttattat gggctactta tatcgagaaa aagatgagaa aatgggtacg
    28741 attttgatga tagcaggggt agctggagca atctttggtg tacttttagg gatgtcaatg
    28801 tactgataag agggataaga gcaaattatt ttggagatag gagataaaaa gttgaataaa
    28861 gtaaatatga acaagaagtt tgtcattata ggtatcgttg tcttggctat tataggtatc
    28921 attttttcaa aaatgacagg tacatctgga ttagagaagt catctaaacc attggtgaca
    28981 cagattttac aagaacagta caacttaaat aggtcatgtg atgatgtgac gattactcat
    29041 gaaaatggag ataacacata ccgggctaaa gctacgttag acaatggaag tgctatcaat
    29101 ataaatgtcg agtactatcc aaagaaagac cgtgtatatg tagagatacc atatactgag
    29161 gtgttaatgt taaattgatt taaatgtatt atgtataccg tccaaacagg aactcctaaa
    29221 ggtgtaagct tactaaggag tttttttgat tccctgtaaa taaaatacta atatagatga
    29281 gaaaaataat gttataataa ttgatggaaa ttgtttttaa agagctttaa aaattgggtt
    29341 cttacattgt tgattaaatg ctttaaaaga ggagctt
//
LOCUS       DADVXB010000020        29111 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.020, whole genome shotgun sequence.
ACCESSION   DADVXB010000020 DADVXB010000000
VERSION     DADVXB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.020"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1031)
                     /locus_tag="KB902_000686"
     CDS             complement(<1..1031)
                     /locus_tag="KB902_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6807533.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="KB902_000687"
     CDS             complement(1113..1802)
                     /locus_tag="KB902_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6807534.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB902_000688"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB902_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBB6807535.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="KB902_000689"
     CDS             complement(2329..2832)
                     /locus_tag="KB902_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBB6807536.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB902_000690"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB902_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBB6807537.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB902_000691"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB902_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBB6807538.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB902_000692"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB902_000692"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBB6807539.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB902_000693"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB902_000693"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBB6807540.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="KB902_000694"
     CDS             complement(6444..7463)
                     /locus_tag="KB902_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6807541.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="KB902_000695"
     CDS             complement(7636..8541)
                     /locus_tag="KB902_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6807542.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB902_000696"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB902_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBB6807543.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB902_000697"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB902_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBB6807544.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB902_000698"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB902_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6807545.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="KB902_000699"
     CDS             9754..10398
                     /locus_tag="KB902_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6807546.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="KB902_000700"
     CDS             complement(10454..10957)
                     /locus_tag="KB902_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6807547.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="KB902_000701"
     CDS             11554..12519
                     /locus_tag="KB902_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6807548.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="KB902_000702"
     CDS             complement(12618..13790)
                     /locus_tag="KB902_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807549.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="KB902_000703"
     CDS             complement(13777..14922)
                     /locus_tag="KB902_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807550.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="KB902_000704"
     CDS             complement(14936..15868)
                     /locus_tag="KB902_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807551.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="KB902_000705"
     CDS             15985..17064
                     /locus_tag="KB902_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6807552.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17690
                     /locus_tag="KB902_000706"
     CDS             17061..17690
                     /locus_tag="KB902_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6807553.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17800..18027)
                     /locus_tag="KB902_000707"
     CDS             complement(17800..18027)
                     /locus_tag="KB902_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6807554.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18130..20718)
                     /locus_tag="KB902_000708"
     CDS             complement(18130..20718)
                     /locus_tag="KB902_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBB6807555.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20738..21397)
                     /locus_tag="KB902_000709"
     CDS             complement(20738..21397)
                     /locus_tag="KB902_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6807556.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="KB902_000710"
     CDS             complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="KB902_000710"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBB6807557.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22170..23036)
                     /locus_tag="KB902_000711"
     CDS             complement(22170..23036)
                     /locus_tag="KB902_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6807558.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23145..23786
                     /locus_tag="KB902_000712"
     CDS             23145..23786
                     /locus_tag="KB902_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBB6807559.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="KB902_000713"
     CDS             complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="KB902_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBB6807560.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25227..26126)
                     /locus_tag="KB902_000714"
     CDS             complement(25227..26126)
                     /locus_tag="KB902_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6807561.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26128..26925)
                     /locus_tag="KB902_000715"
     CDS             complement(26128..26925)
                     /locus_tag="KB902_000715"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBB6807562.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26903..27607)
                     /locus_tag="KB902_000716"
     CDS             complement(26903..27607)
                     /locus_tag="KB902_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBB6807563.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27738..28313
                     /locus_tag="KB902_000717"
     CDS             27738..28313
                     /locus_tag="KB902_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBB6807564.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28431..29108
                     /locus_tag="KB902_000718"
     CDS             28431..29108
                     /locus_tag="KB902_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6807565.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8567 a         6169 c         5232 g         9143 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcta gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg
    17221 acatccgcat gcctaaacaa acgggcatcg atgctgccaa agaaattttg gctaaatttc
    17281 ccaaagccat ccttttgctt ttgacgacat tcaaagatga agaatacatc cgcgaagcat
    17341 tttccatcgg tgtcaaaggg tatttaatca aacagaactt gcaagcgatt attccttctg
    17401 tcaaatccgc ttataatgga caggccgtat ttggtaatga aatcatcgag actttcactc
    17461 aaatgatgaa gaataaaccg acgattgata gtcatgctta tgcttctttt agtgaacgtg
    17521 agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct
    17581 tgtacttgag tgacggcact gttcgcaatt acatcagcca attactagaa aagctagatt
    17641 tacgggatcg cacgcaattg gctatctatt tttatcagca tttgcaataa gtcttatcta
    17701 acacaaaaaa acctgaatga tgctccttcg catcattcag gtttttttca catcttctat
    17761 tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat caaggattcg cagggctgcc
    17821 aggattcgtt ggattgttcg gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt
    17881 ttctagtttt gattcttcac gatcgtctcg ttctacatca ggactttcat tcaatttgaa
    17941 ttctttttcc atctcatcta actttttaaa gtcattgcca gattcttttg ctaatttcgc
    18001 taatttatct tcggtttctt tagccataaa gtaacgcccc ccttttgatt tcagcttagc
    18061 atatcacact gaaaaaacaa aagaaaacgc taaccaacga tcatttttag ctatttctca
    18121 tctttaaaat caagcatttt ttgccggtat aaaatcgtag ggagaactgt tttccatacc
    18181 aatcatcgga tctactaact ggttatcgat cacttctgct gtaagaacga aatctttaga
    18241 aacagcaggt tctacctctt ctttcttttc ttctccaaca aatgaagaaa acagatctgg
    18301 ttccactgtt tccattactt ggtttttcgt ttcattcgtc ccactgtcat cttctacagg
    18361 tagcttttct tttacaaccc gtggctcttt tgtatagttc ccatcttcaa atggatcatt
    18421 tccgaccaaa gaatcttcat aagctgctag tttggtccgg agagtgatat tcattttatc
    18481 attatccatg atccttgatt tcaacgtagt catccggctt gctgattcat tcgctacaca
    18541 agtgacatag gcttgctctt cccctaacaa aatcaacagt tccttactgc gagtcactgc
    18601 cgtgtagagc aaattacgct gaagcatccg ctgatattga tggaccatgg gcaaaataac
    18661 catcttgaat tcactgcctt gtgatttatg gattgagcaa caataagaaa gagtgatttt
    18721 attccattcg tttcttttat aagtgacctc atttgcatca aactggataa ctaattcatc
    18781 cactttatct tcagaatctt ttgccaagat gatacccgtg atttctccca tatctccatt
    18841 gaatacattc aattcgggag tattgactaa ttggaggact ttgtctccta tccgataaac
    18901 ggtgtcgttc caatgtactt ccttttttcc aggtttccct ggattgaata tctcctgcat
    18961 cattttattt aacgcatcga tccctgcagg tccccgatac attggtgcta atacttggat
    19021 atcttgtgca cggaatccct tatttttcgc tttttccaca attttagaga tcaagggttc
    19081 aatttgataa gcatcacttc ggaaatagga acgatctttt tgattctttg tgaaatcttt
    19141 tggcagacgt ccttctttga tctcatgggc aagaggaata atactagaac catcaccttg
    19201 ccgataaatc tgattgagtt ccattttggg aatttgttcg atttccaaaa gatcatggag
    19261 tacttgacca ggaccgacag agggaagctg atctttgtct cctactaaga taacttgcat
    19321 attcgtcgga atcgctttga ataatgtgtt agccagccat gtatcgacca tagacatctc
    19381 atcaacaatc aaaagtccgc cttctaattc tttcgtactg actgaaggtg ttttttcccg
    19441 tccattcagc cccagaagac gatggatcgt actggcaggc agacctgtcg tttcgttcat
    19501 tcgtttagct gctcggccag ttggtgctgc aagtagaata ggaaaaattt cttgggtata
    19561 ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa agattgacga ttccgttgat
    19621 cacagtagtt ttccccgtac ctggtcctcc tgttaaaata aatagagggg aacggattgc
    19681 ttcagcgata gcttgttctt gcgaaggtcc atactgtatg ccgaatattt tttcgatacg
    19741 ccgaatattc ttctgcactt ctttttcagg ataatggatt tcttttttac gactgagaag
    19801 gcgctggatc gaattaccga tcccccattc agaaaagtac aaactgtttt cgtaaagatt
    19861 agtctcttct tgttgtatct ttccttcttc aacaagttgg ataattacag tagcaacctg
    19921 atcaggctgg atttcaattg ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa
    19981 tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa
    20041 gatagctgct cgaattcttc tcggtgaatc tgctgcaata ccgatttgtt cggctagatt
    20101 atctgcacgt ttgaacccga ttccttctat gtcttcgact agctggtacg gattttcttc
    20161 gatgatatcc aaagactcgt tcttataggc ctggtagata ctgaaagcta actgactacc
    20221 gaacccgtaa cgattcagtc ccatgatcac ttgatccatc ccgtggttta gccgaatcgt
    20281 ctcagcaagc atttctcttt ttggcttcgt caaaccggag atttgtttta ataccgaagg
    20341 atcagcaatg attttttcga tagcatcttc tcccagcaat tctacaattt tttctgctgt
    20401 tttcttcccg attcctggga atttttcgct ggaaagatac gctacgatcc catttgcagt
    20461 tgttggcttt tcttgctcat atctttcgag tttaagctgc cttccgtatt taggatgatc
    20521 cactaattct ccataaaaac gataagtctc attttcttga atatcgccga aacttccggt
    20581 gactacaatc tctttttcac ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac
    20641 tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg
    20701 catttcttct ggctgcatcg gaagccgcct ccttcttcta tagtaaaggt tctggtgctg
    20761 tttcagttcc taaaaaatct gtttggttcc atactttcag ttcatatggc aataatctgc
    20821 aaggctcttc agtctctaaa atcgtcaaac tactattgaa caatccaccc atttcacgca
    20881 actcacttag ctcttttcct gtcatccatt gaatggctgc agttaaagaa gctccatgtc
    20941 ctacgaataa aagtgggcca tctttatgtc gggcaaccgc atctgctaca acagtttcga
    21001 tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg agaaggatca tacagatcta
    21061 aatgattacg caaattcggc agattatccg gatatttctg gtacatttca tcgatcgact
    21121 gaccttctaa agtacccagc cctagttctc ttagcttatc tgtataaaaa atctctaccg
    21181 gacgagcaag ctctttgttg ataccttctg ctgtatcacg tgctcgcttt gctgtactgg
    21241 aataaattgc tttaaaagga acatatttta cctttttccc aaatgctttg atttcttcgt
    21301 aactttgtgg caaaagcgga gaatcgccat tgctcccttg aaaacgtctt tcctgattcc
    21361 attgtgtctt cccatgtcgg gtaaaatata gttccatacg cagcaaactc ctgtctttct
    21421 tttattttac tctataataa actgtctaat ccagcttgtc attttcatag tgatgcgtca
    21481 attctaaatt agggaatcct tgctggcgaa gtgcttcata cactatcatt gcagctgtat
    21541 tcgataaatt caatgagcgg acatgctcat cattcatagg gatgcgtaaa cacttttctt
    21601 cgttttcacg cataaatgtt tctggcaaac cggttgtttc ttttccaaat aaaaagaagt
    21661 gctcttctcc atcagcaaaa ttttcgtcac tatatacttt atgggcaaat tttgagatca
    21721 aatgtagttt acgattacct aaaaatgtta aaaaagcttc taaattactg tggtaagtaa
    21781 tatttacatc attccaataa tccaaccctg cccgttttag atgtttgtca tcagttgaaa
    21841 aacctagtgg ctcgattaaa tgaagcggag tattcgtggc tgcacacgta cgggcaatat
    21901 ttccagtgtt tgcagggatt aatggttcaa ataaaacgat atgattcatc aggatcattc
    21961 ctctcatatt tatgttcgtt tctattttct gacaatttga tttttgcata aaaaaaaacg
    22021 tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt gaagctcttc tcactaactt
    22081 ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca acttgttgct aatataacac
    22141 cctcaacttt tttttgcaac ctctactcat taaaaactgc tagaaaaacg ttttctctta
    22201 gttcctttta ataattctat gtcaattgta atcttcttca aaggattctt atataagtct
    22261 gctttgattc gctcttctac ctgccattct aaaggtgaca tggccaaaag atctttttga
    22321 ttttcctctg gtatctcaaa ttcataggtt acacgctgac gttcagttaa tttcattgct
    22381 tcagcaaact tggctactac acgttcattg gaataactct gtttttcagg ttgattcgga
    22441 taaaaagcct gacgtagttc ctttaaataa ttttcttgtg gcaccacctt caacacttct
    22501 ccatcttctg agagtacacg ttggaattct tggtaatgag aaggcgaaaa gatatttaaa
    22561 accgcgttga atgtttgatc agcaaacggc aaattggtca aatcagctac acaccaaaat
    22621 gcttcggcag attgttctgt agctgcgtag actccttctt ttgaaatatc aaatccaaca
    22681 gcattttgaa tctttttcaa ttttgaaagt tcattcaaga agctaccttc tccgcagcca
    22741 acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga
    22801 tacatgccag attggatcat tctacgcctt ggaacgaaca ttccttgatc gtattctgtt
    22861 ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta
    22921 tttttgcata tcaagccatt atcagacttt tttacttctt cttggcaaac cggacagcgg
    22981 aacagctgat gattttctgc caaaaactgg cgtcctcggt caattttttt taacatagtt
    23041 ccccctcatt tctgttttat cttaccgtta gatgctcact ttggcaactg ctaaaaatat
    23101 gatacaatgc ctagaagaaa gtgaaagata aaggagaaga ttagatgatc aaagaatttt
    23161 gcgctgaaaa ctacacatct attcctctag caattgctag aggagccgat cggatcgaat
    23221 tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt
    23281 taagttatgc tggggaaaaa gatatccccg taatgacgat tattcgtcct agagggggcg
    23341 acttcgtcta taacgatatc gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga
    23401 aattagggac ggatggcgta gtatttggtt gtcttactcc ttcaggctgg ctagacgaag
    23461 aggccttaga actattgatc gaaacagcag aagggttgca gatcaccttc catatggctt
    23521 ttgacagtat tcctgaagat cggcaattcg aagcaatcga ttggctggta gaacatggtg
    23581 ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac tattgtagaa aatttcccac
    23641 ggcttaaaga attgattgcc tatacagatg gccgcttaat cattttgcct ggtggtggtg
    23701 tcactgcaga gaatgcagca catgtagcta aagaattgaa cgtaagcgaa gtacacggaa
    23761 ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa aaacatttgc aacaggcata
    23821 atgcttattg caaatgtttt tgttttttta cataaaatag cccataaata aagaagcaat
    23881 attgaaataa atcagtacac tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc
    23941 tactgctgga tcaaatccta gacgatccat tagcatcggg attaaactac ctgcaagatt
    24001 cgccactgtg attgcaaata gcatagccat ccctatgaca aaccccaaga taaaattatg
    24061 tttccaaaaa cctacgatta gaaaaatcgt gatccccgta acagctcctg tgacaacgcc
    24121 ggtcaagact tcagccaaaa caagtcgaac aaatccatga tctttctcat cagaaatcgc
    24181 aagtcgacga acagccacag ctagcgactg ggttccagca ttaccggcag ttcctgtaat
    24241 cagcgaaatg aagactgcta aaatactcgc ttcacttacc aagtcttcat agtgactgat
    24301 taaagaagcg gtcgacatac ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga
    24361 cgctgccttt actggatttt cattaatttc ttccacattg accccggcaa gtcctgaata
    24421 atcgctagca gcttcatcat caataacgtc gatgatatca tcgactgtga cgattcctaa
    24481 caaatgatca tcataatcgg taacaggaag agctaagaag tcataatctc taaatgtttg
    24541 tgccacatct tcttggtcgt cgcctacatg aactgaaagc actcgttcgc tcatcagatc
    24601 agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc agagaaataa cccctactag
    24661 ctgaccttct tgattaacga catagatgta atagattgtt tcagctacat ctgcttcgtt
    24721 cttcagcacg tacatcgcag agcgaacagt ttgattggct acgatcgaaa caaattcagt
    24781 tgtcatgatc gcgccagccg tttcatcctc gtaatggaga agttccttga tttcactggc
    24841 atcgtctgcc gacatcaaac ttaaatattt agcaatttgc tttttatcca gcgtattaag
    24901 caagtcaaca gcattatctg tatacatctc agaaagcata tcagctgcat agctaggacg
    24961 catttcatct aggtattctt tcatatgttc gttgtcttct tcaatcacat cgaacatatc
    25021 cgctaattct ttaggcgaca gataggaata gatcagctgc ctgttctctt ctgtaagaga
    25081 ttggtagaat tgcccctgct catagatatg catctctaaa aaactgtttc tgaatgcctg
    25141 aatattattt tcccttaaat cttgagtcaa ctgggcaaat ctttcctcta attcttgatt
    25201 ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc gtctcacaac tgcctccatg
    25261 tctgcggcta aaggctgctt gaactccagc aactcttctg taaatggatg gtaaaaacgc
    25321 agatcataac aatgaagggc ttgtcttttt attcccagat ccattcgccc gccatacata
    25381 tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt
    25441 cctgtatgca gctggatatc aactaacgcg atttctgtta gtcgcttctc tatccagtac
    25501 tcagtctgtg ccgaacgtcc ttcatcagag accattcgct tcaatagcga agaataatct
    25561 cgggcgatcg gcaaatcgat atgtccatgt gccgataaat ctgaaagcct tccactgact
    25621 aaggcctgat attttttcac aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc
    25681 gcaaatccat gctttgcaaa aagcatcaag ccagatgtat cccgatctag tcgcgtcacc
    25741 acatggatta cttggttttc gtaaccttgt tttttataat aagcctttac acgattagcc
    25801 attgtcccat ttggatggta ttgggcagga atagacgaaa cgcctgctgg tttatttact
    25861 accagaacgt gttcatcttc atacacgata tcgatcggtg tttcatccaa aagtacggtt
    25921 tcatgttctc cttcagcagg aatcacaatg gttaccttat catccttagc tagagaaaac
    25981 aagacatttt ctacttgatc attaactttg atttgaccgc cttgaaattt tattttcgct
    26041 aacagaccct ttgagatccc tttttctttt aaaaaatatt ttacttgctg agaatgatct
    26101 ttctcataat cccatgtaaa ctgcatatca atcctcacta ataaaggcat ctttcacacg
    26161 atgccaaaaa tgcatatgtc gataagaagc aaaatggatc cgttcttctg ctattcgata
    26221 ataaattgag cggatatttg cttttgcgac attcaattga tcaaccgtta caagataatc
    26281 ttctgtattt tccaatttta tttctagcca ttcatcatgg gcaatcacga tcggagaacc
    26341 caaagtacga aacactcgat tattcagtga agcaatctct gccaactgaa aggcattgat
    26401 actaggatgg atcacagcac cgccgacact tttattatat gctgtcgaac cagtaggcgt
    26461 agaaatcgtc aatccatctc ctctaaaact ttcaaacagc tcgtttttga tgtatacatc
    26521 ggctaccatc gtacgattgg cccgtttaat cgttgattca ttcagtgcta aaaaatgctg
    26581 gtccggtgtt tcatccaaat aactgatccg aacatccagc aagggataac taacactttg
    26641 ttcccggttc gttcgtaagc tgtctactag ttcttccagc tcgtaatccc gccaatccgt
    26701 gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc acatcattca gacaatgact
    26761 gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg actgagatga ccaattctgg
    26821 ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac
    26881 ttctatagtc tttgcttctt tattatgaac gatcgctact ttcatcccct gcctcctctc
    26941 tttcgctttc tttcttcaaa agcgttcgat agtagacatc atctgatttt cctcttccat
    27001 gggagaataa ccgctgtgct tcttggattt cttcacggat actggacatc tcttcatcca
    27061 actgataggc agcttctgcc gcacgctgaa gtcgttcact catttcttct ggaaaaacgc
    27121 cttgatattt ataattcagc gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc
    27181 gaatctggat ttccgccaaa attttcttct caccgctgat cagctgtaca ggatactcga
    27241 tcaccagatg ataagaacgg tagccacttg cttttttatt tgtgatgtaa tctcgttctt
    27301 ggagaacttt catgtctttt cttttacgga tgatctcaac aacttgatgg atatcttcta
    27361 caaactgaca catgatcctt aacccggcaa tatcagacat ttcttcttct aaacgtccca
    27421 ttggaatatg ccgtaattgt gattttgtta caatactatc gactggcttg actctcccag
    27481 tgacaaattc aatcgggaca tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca
    27541 gtttcacttt caattctgat acagtttgtt catatggtgc taaaaatgct tcccaatctc
    27601 gttccatagc tgatacctct acttcattaa cattcattgt ttattctacc atatatgcaa
    27661 agttttttcg tactcttgat ttatgcattg accaaaaaaa gaaaattagg caaaatagac
    27721 aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga atataaatct atgctgacaa
    27781 agcaagagta cgagatattc atcgctcact atcaattaac agataaagat ttccgtgtac
    27841 agactaatat ttatttcgat accgttgatg aacagctgaa gaaacaaaat tgtggcctac
    27901 ggatccgttt cgttggtcat caagctgaat atacattaaa aacacctgct gaaaaagggc
    27961 gtctcgaaac aacggatacc tttataacag aagaagcaga agcatttatc ttcgaaaaac
    28021 gtctgcctcg ttcaggcgca gtttttcaaa aactttctga tttgaatatc gatcctgctt
    28081 cattaatcca aaccggaaag cttacaacaa aacgagctga attccctatt gaagaaggac
    28141 ttttagctat tgatgaaagc tggggagaca atctacacga ttttgaactg gaactagagg
    28201 taggggatgc atctgtggga aaaattgctt ttataaattt tttaaaacgt ttttctttac
    28261 cttatcgtcc tgctaagaac aagatccaac gtatgcttga agctaaaaat tagaaacctt
    28321 tcattttcac aaggcacttg agttcatttt tttacttttt tctgttaagt tataggatgt
    28381 gaaagaatct agtcactagt tgtatagaat ctattttggg ggagattcat atgatcgaaa
    28441 tctatttatt tgttaatcct ttaggggaat actgtttcga aatggaacaa cagttattac
    28501 aatttatcga agaagagtac gggacaccat caaaagaaaa gatgcaattt cgctttcttc
    28561 ctttggtcaa tttgcagaca attggggatg tcatgcaaca aaaaggaatt tctcagaaca
    28621 atcttgagga acgtaatcac ttattctcaa tgacttattc tgcagcattg gactgcaaag
    28681 cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt gatcaaattg caagaagcag
    28741 tcggctgtaa tgacatacca tattctcaag aacttgctga atccatattt gaagaaatcg
    28801 gcggcgattt gaatatgttt aaagaagatc gtcagtctga cttcgttaaa gaagtattct
    28861 tttctgatca aaaaattgct cgggaaatgg gcatcacaaa acacccttct gcagtcgttt
    28921 acaattatgc ctgcgaccgt gattttggtg ttttagtaga agtaaaaggt acaagtagcc
    28981 tttggagaat cacagagctg tgtaaaacaa cagataactc atatcaagtt tttaatggtg
    29041 aacatttaca tacaaatgat tctcagttcc attcaagaac tagccattta cacttgcttt
    29101 ctaattaaaa a
//
LOCUS       DADVXB010000021        27776 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.021, whole genome shotgun sequence.
ACCESSION   DADVXB010000021 DADVXB010000000
VERSION     DADVXB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.021"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(338..2230)
                     /locus_tag="KB902_000719"
     CDS             complement(338..2230)
                     /locus_tag="KB902_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807566.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2227..3954)
                     /locus_tag="KB902_000720"
     CDS             complement(2227..3954)
                     /locus_tag="KB902_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807567.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3970..4620)
                     /locus_tag="KB902_000721"
     CDS             complement(3970..4620)
                     /locus_tag="KB902_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6807568.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4824..5120
                     /locus_tag="KB902_000722"
     CDS             4824..5120
                     /locus_tag="KB902_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6807569.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5312..5934
                     /locus_tag="KB902_000723"
                     /pseudo
     CDS             5312..5934
                     /locus_tag="KB902_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
     gene            complement(6026..7192)
                     /locus_tag="KB902_000724"
     CDS             complement(6026..7192)
                     /locus_tag="KB902_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6807570.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7204..7557)
                     /locus_tag="KB902_000725"
     CDS             complement(7204..7557)
                     /locus_tag="KB902_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6807571.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7685..8707
                     /locus_tag="KB902_000726"
     CDS             7685..8707
                     /locus_tag="KB902_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBB6807572.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8726..8887
                     /locus_tag="KB902_000727"
     CDS             8726..8887
                     /locus_tag="KB902_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807573.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9146..9580)
                     /locus_tag="KB902_000728"
     CDS             complement(9146..9580)
                     /locus_tag="KB902_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807574.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9690..11549)
                     /locus_tag="KB902_000729"
     CDS             complement(9690..11549)
                     /locus_tag="KB902_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6807575.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNLYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11667..12827)
                     /locus_tag="KB902_000730"
     CDS             complement(11667..12827)
                     /locus_tag="KB902_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBB6807576.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13134..14558)
                     /gene="araA"
                     /locus_tag="KB902_000731"
     CDS             complement(13134..14558)
                     /gene="araA"
                     /locus_tag="KB902_000731"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBB6807577.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14574..15272)
                     /locus_tag="KB902_000732"
     CDS             complement(14574..15272)
                     /locus_tag="KB902_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6807578.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15229..16890)
                     /locus_tag="KB902_000733"
     CDS             complement(15229..16890)
                     /locus_tag="KB902_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBB6807579.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17108..18508
                     /locus_tag="KB902_000734"
     CDS             17108..18508
                     /locus_tag="KB902_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBB6807580.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18760..19839)
                     /locus_tag="KB902_000735"
     CDS             complement(18760..19839)
                     /locus_tag="KB902_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6807581.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19925..20884)
                     /locus_tag="KB902_000736"
     CDS             complement(19925..20884)
                     /locus_tag="KB902_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6807582.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20896..22407)
                     /locus_tag="KB902_000737"
     CDS             complement(20896..22407)
                     /locus_tag="KB902_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6807583.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22429..22992)
                     /locus_tag="KB902_000738"
     CDS             complement(22429..22992)
                     /locus_tag="KB902_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6807584.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22998..23861)
                     /locus_tag="KB902_000739"
     CDS             complement(22998..23861)
                     /locus_tag="KB902_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6807585.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23875..24771)
                     /locus_tag="KB902_000740"
     CDS             complement(23875..24771)
                     /locus_tag="KB902_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807586.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24946..26235)
                     /locus_tag="KB902_000741"
     CDS             complement(24946..26235)
                     /locus_tag="KB902_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6807587.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26207..27724)
                     /locus_tag="KB902_000742"
     CDS             complement(26207..27724)
                     /locus_tag="KB902_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6807588.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT         8104 a         5860 c         4819 g         8993 t
ORIGIN      
        1 aaactggctt ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta actccgagtc
       61 acaaggagca atttcaaaaa acagcttctc aggtttgttg actattgtga cttgtgaccg
      121 aggagttggc aggagaacac cgtttaagga agaggttgta aaatcagcgg tttgacctga
      181 gtattagaga tacaaaacgg aaaaatagct tctcatattt tgccgttttt tgagctaata
      241 ccgaaggaca gctgattgaa caccgtttat tcggaaaaag ggactgtgac acgacttttg
      301 tcacagcccc taaaaaaaat aataaatttg tactattcta tgaagcttct tcttcagaaa
      361 actgactgtt ataaagatct gcatagaatc cgtctttttc catcaatgta tcgtggtttc
      421 ctgtttctac gatcgaacca tgattcatca caataatgtt gtctgcatcg cgtattgtag
      481 acaagcggtg agcaacaacg aaacttgtcc ggttttccaa taggcggttc atcgcttttt
      541 gaatcagtat ttctgttcgt gtatctacac tagatgttgc ttcatcaagg atcaggacat
      601 ctggatttgc taagaatgcc cgcgcaattg tgattagctg acgctgccct tgcgaaatat
      661 tgcttgcatc ctcgtttaat acagtgttat atccttctgg caatttacga acaaaatcgt
      721 ctacgtgagc agctttagca gcctcaatga tttgttcgtc tgttgcatcg tcgttcccat
      781 atttgatatt gtcatagata cttcctgtaa acagccaagt atcttgcagt accattgaaa
      841 actgtgcgcg caattcatca cgtgaaagat cacgggtatc tacaccatcg taacgaatac
      901 tacctccaga aacatcgtag aaccgttcaa gaaggttgat cagtgtcgtc ttccctgcac
      961 cagtcggacc tacaatagcg accatctcac caggtttgac atccaagtta aaatcagtca
     1021 ttagcaagtt atctggtgtg tagccgaatt gaacattttc aaaacgaact ttgtatggtg
     1081 tatctttttc ttctggaagg ccagattttt cattggacat ctcttcttca tccaacactt
     1141 caaatacccg ttcggctgaa gcaactgttg attggatagt gttcatcaaa cttgcaagtt
     1201 gagtgattgg ttgagagaac tgtgttgtat attgcaagaa cgcttgaaca tcccctaatg
     1261 tcatgttccc atttgcaact tttactccgc ctagtacagc gacgaacaca tagcctagat
     1321 ttttaacgaa attcatcaac ggcatgatga ttgccgaaat aaattgagct ttccaaccag
     1381 cggcatacag attctgattt tctttttcaa atacttcctg gtctttttcg gtatgattga
     1441 atgttttaac aatggtatga ccaccatatg tttcttctac ttggttattc aataaaccta
     1501 aacttttttg ctgatctgcg aaaaacactt gtgatttcgg cgctacgatc atcacgatga
     1561 tcaagcttaa agggatcatc aataacgcga ctaacgtcaa ttgccagctg attgaaagca
     1621 tcatcacgat gaccccaatc aatgtgactg cactagttac aaattgagtc aaattttgct
     1681 gcagcgtgct tgcgatgtta tccatatcat tgattgctcg agacatgata tccccatttg
     1741 tatgtgtatc ataataggaa atcggtacac gattcatttt ggcttccaaa tcatgacgta
     1801 attcataaac tgttcgttgg gaaacacgtg tcataataaa ttgctgtaaa aagttgaata
     1861 cagcagaaat caaatacatc acgattactg tcgcaatgat ctgcgcgatt ttatcaaagt
     1921 ctatcggaaa ttttgttact tgttggcctt gttgcatctg ttgagcgcca gccattacac
     1981 ctttgaatat ttctgtggtt gctttcccca agacctttgg tgtttggatt tggaagatca
     2041 cggctgctat tgctagtaca aatacagcga tgatcgcaac catacgttta gacatatagc
     2101 caaacaatcg gcgtaccgtt ccccagaaat ttttaggctt ttcacctttt acaccgagat
     2161 ttctgccagg tccaccatgt cctggaccgc ctgctggtcc atgagaggga cgtgtgtttg
     2221 ttttactcat gctaagtcct cctctcttag ttgtgaatga acgatttctt gataagtttc
     2281 gtttgttgct aatagttctt catgtgttcc tttgccaacc agttttcctt catctagcac
     2341 aaggatcata tctgcatcca ttactgtact tactcgttga gcaactaaaa cggtgatact
     2401 ttctttcata ttcgttttca atgcttggcg aagattggca tccgttttga aatccaacgc
     2461 tgagaaggaa tcatcaaaca catagatatc tgctgttttg actaatgccc gtgcaattgc
     2521 cagacgctgt ctttgtccac cagagaagtt tcctcctcct tgttccacat ggctatctaa
     2581 gccatcttcc atctctgaaa caaaatcttt agcttgtgcg atttctaatg ctttccaaat
     2641 catttcatct gttgcatccg gcttaccata ctgcatattg tctcggatcg ttccagagaa
     2701 cagaactgct ttttgaggaa caaagcccat taattctcgc aaattatatt gagtcatgtc
     2761 actaatgtcc gttccattta tttggatcga accagattcg atgtcatata atcgagggat
     2821 caaattgact aaggtcgttt tacctgaacc agtcccccct atgattgcga cgatctcgcc
     2881 cgacttggct tggaaatcaa tatcttccaa tgcaagtttt tctgctccat gatatcgata
     2941 attgacatga ttgaaggcca atgttgcgtt ttttccagca aaagaaactg ttttaggatt
     3001 ttcagggtca tggataccga ttttttcatc caacacttca ttaatacggt cagctgaagc
     3061 ttgtgcacga ggcaccatga taaaaatagc ggaaagcatc ataaagctga tcaagatctg
     3121 catcgcataa gtcataaatg caatcagatt accgacttcc aaagtcatat ctgctatgta
     3181 gtgtccacca aaccaagtga ttgctacgtt tgtaccgctc atgatcaatg tcatcattgg
     3241 catcatcaat gcgacgatcg tattaacttt gattgccgta tttgtataat ctttattcgc
     3301 taaatcaaaa cgattttctt caaagcgtgt cttatcgaat gctcgaatca ctctgacccc
     3361 tgtcaatcct tctcgaaata ccaggtttaa acggtcagtt ttcttttgca tacttttgaa
     3421 taatggaaca gcaaagtaca tgattccgcc gatcaaaata atcattactg ggatgacaac
     3481 taagaagatt tttgtcaact gatgatcttt ttgataagca agtatgctcg cgccaatcaa
     3541 cgtgattggt gcattgatca tcatacgtaa aaacatttgt gtaaccattt ggatttgagt
     3601 cacatcattg gtcgttcttg tgatcaaaga ggccgttcca tatttatcaa acgcatcttt
     3661 tgtcagactc tctgattttt tatagacatc cgtacgcaat tgcttaccca gtttctgtga
     3721 ttcacgagta gcaaaaaatg tatttgcgat agcagctaag atactgatca aagaaaagcc
     3781 gatcatcaca aaacctgtat gccaaatata atcgacatct ccttgcgcta cccctttatc
     3841 aataatattg gaggtaagtg tcggcaaata taaatctgcc agtacttgga tcaccatgaa
     3901 aactgcagct gcaattgctg aagtcaagga gatccgtttt acgattttta gcatctagtt
     3961 cccttctttc tatttatata ctccgttttt cagccaagaa agtttcaaat tgaattcact
     4021 gattgcttgc tctactgagt aatcttcaga tgttgaaaat aagcgatacg aatgcgcaat
     4081 tgttgtaaat acagtattca tcactaattg gatcagtaat tccaattcat gatcattttt
     4141 tactttcagc ttcgtccgat cgatcaattc aagcaactct tttgcatctt gtttgtgttc
     4201 tttatgtgga tcgtgaggcg ttttttggcg actcgtatga ggagcgactt ttcttgaggc
     4261 acggtaatcc atgttcataa acaagttacg ataaaaagaa gcattctcgc cttccaaaat
     4321 ctcataaatc attttagaaa aataggattc gaatcctttg aatagatcac catcggattc
     4381 tttcattagt tgtaacatat ctttagagct gtcacgtctc attgtctcaa agtaataaaa
     4441 ataaagatcc tctttatctt caaaatactg atagaaactg cctctaggga tatccgctaa
     4501 tttgacgata ttagcaatcg aagcttcttt taagggtact ctagaaaact cgattctcgc
     4561 agcctcgatt agtctttttt gtttttcttt aggcaaatgg aaaaatgtct gtgtcggcat
     4621 atggattctc ctttctttca agatgacaca ttgtcatatg acgctatgtc attataacac
     4681 ctcctacctg ttttgcaaga catttgcata gtttttttca ttatcatccg atacattaaa
     4741 aaagtgataa gaggaatcct tccatttgaa ttaatgagag ttgcccatta aaatagccac
     4801 atactaaaca aaggatgaga taaatggccc aatcaattag tgtccaagac ttcaataaat
     4861 tgcctctcga tgctgacagc atcgttttag atacaagaaa taccttagat tacacaaaaa
     4921 accacttaag ccactcgctt tctatccccg ctgctatctt gccaagacaa ttaaaaaatc
     4981 tagatccaaa gaaactttat tatattctaa gctatacagg caggcgatca gaagcattag
     5041 ccgatcaact tactgctaat ggttttcgtg ctgtttatat cattggtggg atggaagctc
     5101 ttcagtcgag tgttgcttga atattgcttg ttagattcaa aagaggctgt gacaaaaaat
     5161 cgtgtcacag cctcttttat accctgtctt tttttagtta tttattcttc aaccttatca
     5221 atatgacttg atagcctttt ctttttcgag taaactgatt ttgttagtca tagttataac
     5281 aatcatagca ataaaaggag aaggtaagca tatggcatct gttttagtag tcaaaggtca
     5341 tcccccctaa ctgcagaaga atcgcgcaca gttaaggcat tgacgtcttt tttaacaagt
     5401 tataaagaaa atcatccaga tgatgaagtg actgttttgg aactttatcg cgatgatatt
     5461 ccggaaatcg atgaagaatt attatcaggt tgggaagcat tacgtgctgg tgcagaattc
     5521 acttccttat cagaaagtca acaacaaaaa attgctcgtt tcaatgaatt gactgatcag
     5581 ttccttgctg ctgataaaat cgttatcgca aacgccttat ggaatctaaa tatcccaaca
     5641 aaattaaaag cttggttcga taccgtcaat gtagctggaa aaacgttccg ctatacagaa
     5701 aacgggccag aaggattagt gacaggtaaa aaagcactgc acatccaatc taatggcggt
     5761 gtatacaacg gacaagactt tgcctctcaa tatgtaaaag gtattttaaa ctttgtaggc
     5821 atcgatcaag tagatcagct attcatcgaa ggaatcgatt atgaccctga ccgtgcagat
     5881 gagttgatgc aaaatgcatt agataaagct gctgctttag gtaaatcatt ttaaaaattg
     5941 agataaatgc atacaaaaga gacagaggaa aaaatcttca aagcagcatt tgtgccttgg
     6001 atattttccc atctgtctct ttttgttatt ctttctgctt tttcaacgga ttttcttcat
     6061 aaagagaaga gattgttgtg taccattcaa aaacatgagt aatcactact ttagctgctg
     6121 cataaacagg aatccccaag atcacaccga tgattccgaa caatttccca gaagtcagca
     6181 gaactaataa aatcgttact ggatggattg ctaactgatt ccctagtact aatggagaga
     6241 tcaagcgtcc ttctattgtc tgctctactg caaaaacgat cagtactttg atgatcatga
     6301 atggacctgc tacaatggct aaaaagatag ccggaatcat cgctaaaaat gatcctaagt
     6361 aagggatcag gtttaaaaaa cccgcaataa tccccaacgt gacagcatac tctaaaccaa
     6421 tgaccgcaaa accaatcata aacatgattg ccacagcaaa agccacagtt agttgtcctc
     6481 ttatataaga agaaacttga ctattcattt cactcagcac attcaacgtc ggtttttgca
     6541 tgcgtgtcgg taaaaatttg acaaaataag gtgctaattg tttaccgtct ttcaatagat
     6601 aaaataagat aaacggcatc gtcagcagag ccactaaaat agtcgctacc gcgccgacaa
     6661 aacttccaag actctgaact gtactcttag atatatcttg gatcatatcg cctgccgaat
     6721 tcatgaactt atcacctgct gtttccaact gttcgcgaaa ttggttgaac agcgggtccc
     6781 gcaaaatctc ggttaattta ttatcaatcg tatctacata ttgagggaag ttactgatga
     6841 agctcactgt ttgttcctga atcttaggga tgatcactac gctcccccat gcgattagtg
     6901 caacaaccaa aacaaacagc ccaatgatac tgtaaagcct tggtactttt cgcttttcaa
     6961 agtaatcaac taccggattc atcaagtaat acaagattcc tgctaaaatg ataggcagac
     7021 ctacgattgc taaaaattgc cagattggtg caaacaaata tgaaactttt gtaaataaaa
     7081 agacgatcag caatattaac aatacaacaa gtaaggctgt gactacttga ttatttaaaa
     7141 accagcgcca aaaccacgat accggtctgt tcttcttatt ttttccttcc ataattcctc
     7201 ctgttagtta taaaaaattt ggcttcccaa accaatagca ggcagtctat gcggatgaag
     7261 atagattcca tttgcaattt gtccttcttc tggacaagca tcaaaaatca atgatacgtg
     7321 agctactgtc tttaaattcc cattggccat cggaccgaca taatcgatcg tatatacctg
     7381 atcatcaaaa gcaattgttc cgcctgcttt caaagaaaaa ggttcgtctt ttgatacttc
     7441 ttgaatcacc gaatattttc gtaaggcagc tgttgctgtt ttatcgaaca aaatcagcat
     7501 gggttcttcc ttgtttattg cttctgtccc aatttctgta atctttgcct gaatcattgc
     7561 actctctcct ttaattgctt tcaaaaacag tataacacat tctcattctt tagccgtgtg
     7621 gaataattat gtgatagaat aaaaacgaaa actatttcat tacaattagg aggaatcagc
     7681 tcatatgatc gaaaagataa ttttaggaac ctatacgcgt cgcgaaagta aaggaatcta
     7741 tacgatcgac cttgatacag aaaaagaaga attagccaac ctttcattag ctgttgaaga
     7801 aaatagccct acctatgtag caaaaagtaa agctggcaat ctttacacag ttactagtgt
     7861 ggatggatta ggtggtgccg gtgcgtacga taaggatttt cattttttga atgcggtaac
     7921 agagtctggc gctcctttgt gttatgtagc ggttgatgaa gcacgtcaat tactatacgg
     7981 ggcgaactat cataaaggtg aagtaaatgt ctaccatata ttaggagatg gcgaactgaa
     8041 agcagcagat tcaatattcc atcaagaagc gacaggtcct cataaaaacc aagatcatgc
     8101 gcatgtccac tatacggatc tgactcctga ccaacgatta gtcgtatgtg atcttggtac
     8161 agatcgtgtg tatacttatg atgtgtccga aaacggcaaa ttgaatcttg taactacctt
     8221 cactgcagag ccaggaacag gccctcgcca tcttgtcttt catccaaatg gacaattcgc
     8281 ttatttattt ggtgaattag acagcacagt ccgcgtgctt tcttataata aagaaacagg
     8341 tgcttttgaa gaattacaga aaatatcgac cttgccagaa gaattcgacg gtgaaaatgg
     8401 aggggcagct atccgcattt caaatgatgg caagttcctt tatgcttcta accgaggaca
     8461 taactcgatt gctgtattcg cagtttttga agatggttcc cacattcaaa acaagcaaat
     8521 catctcaaca gaaggggatt ttccccgcga tttcgcacta gatccaagca ataattttgt
     8581 cgtgtgtgcc aatcagaaca ccgataatct gacattatat cgccgtcatc ctgaaacagg
     8641 attactggaa ttactgaaaa aagatgtcta tgtaccagaa tgtgtctgtg tttattttga
     8701 tcgttagtaa gaaaaggaga atgaaatgaa tcagcaagac gtattagaca gactacggga
     8761 agaactaaat attcctttct ttgatgggaa aatcgaagat aaagagtata gcgaagagga
     8821 atatcagaaa ctcaaagccg atttacagaa ctactttgaa caatatgtac agaatgtaga
     8881 aaactaatca gctttccata ctatctgaaa agaacatcag gacaagactt ttccgtctat
     8941 cctgatgttc ttttctacaa ataaaaaacc gccgagatgg ttagactcga cggaaaagga
     9001 gtatttactc gattttgagt aagtacaagg ttgttgttgg ttataggtat gtcattatca
     9061 taaaggattt tgatcactct atcataaagg taatattaca tttatattag ataactctag
     9121 tttttattgt tatcaaagat ttcttttatt ttttcaacaa caaattagtc attttttgga
     9181 tggcagctgt caattggtct gtcgcttggt cttgttttgc ttcagatgta ttgaatagat
     9241 cttcatctac ccctgattca agatcgatac tttggatcat ttcttcacag cctgctacat
     9301 atgaaagata agctttttca aaatttttat gaatgcccat tgcttttgct ggtggacgca
     9361 aagtactgac tttcataagc attgcccgat atttttttgt tccttcttca aataacagga
     9421 tgatctcttc aagagtcgat ttgtccagtt cacttgtttt tccttcatca attgcgtttc
     9481 tgatcacttc atatttcgga tgcattcctt ctccgattgc ttctgtttcc ttgacgattt
     9541 gatcgatgga ctgcacataa tagccaatat tcggtaacat gttcgttttc ctactttctc
     9601 cattgttgtt attatttatt ctacttgttt ttatcctcaa atgacaagta cttgaaaaaa
     9661 tttaatggtt tctatacagc tcgccattct tattcgtgct caaagaaacc atctgctaaa
     9721 ctatattgtt tccctgcgac aatgtcatat tggatcaatt gatattcgtc gtaaatctct
     9781 tgttgcgagc gattgaattg cgcttcttta taccactgtc cgttttgata gtacagttct
     9841 cgttcaaacg ccggaagttc ctgttctaat gataaaagca gctgataaaa gccatttgtt
     9901 gtctgattcg tctgttccat tagattcgct gcaaaataaa acggactggt gattgcatcg
     9961 tgagtcgttt gcttttctaa ttctccttta ctgtcgaaca taagaaattg tgtttcatgc
    10021 aatgtttgtt tgtcattttt tgcttggatc gtatctgaat agatccctgg aagatgatcc
    10081 ccccaaaaaa caactaaagt ccttctagaa agattcttca attcttccgt gaactgcttc
    10141 agtgccgtgc tgctatagga aatatcttgc agataattct ctaagtcaag tgtcccactt
    10201 ccatctgaag tttttgcagg atagtctaga ttatcatact ttccatcgta gggcatatgt
    10261 gtctgcatcg tgactaaatg aatgaactga ggtgtttttt cttccttgag aagtgtcatt
    10321 acttctttgt aagctgactc atcagaaata tatagattat tctctatcgt atccgtatag
    10381 gtcatcgtac gctcgctgat gaactggtca aatcctaatg tctgataaac atcctctctt
    10441 ttatacatcg aagtattgta tggatggatc gctgtcgtct ggtatgattg tgcgtttaac
    10501 gctgaaacga tagaaggaag ctgatccatt tttggtacaa gcatcgtgta aggggtggtg
    10561 agttgcgcat taaataacgc catagaaaaa ccagtcaatg cttcaaattc gatatttgct
    10621 gttccaccgc catagttttg agaaagcata ttgccactat atgtttgatc agctacttca
    10681 taataatctg ccaatggctc accagatact tctacgccgt ttaatcgact aggatctgag
    10741 aaactttcac tcatcacgaa cacgatgttc ggcgactctt cctctacagt tttatttttt
    10801 tcatcggcta gcttctggta tttttcagtg atttctttga tcttttcttt cgaatatcct
    10861 tcaggttcat ccattggttc taccttcaga ttgtacaaaa acccaccgat aaaaccagtg
    10921 ttatagtagt tcattttctg gctgtaaggt atccatagtg ccgttttatt atatgctttt
    10981 cgcaacaaat tatcgggatt gttgaaatta ctgatatacc ctagcagtcc aattgccaca
    11041 agcagtgtcg ttaatcggat caattggaat cgccttcctt ttttcaggct tcgaaacatg
    11101 taccagcaaa acaatcctat cacggttcct gcggcagcta agatcactgt aaacagcata
    11161 gtgccggtca tatctttcag caatccgatt tcagtgatca tcttcaaatc gtctggataa
    11221 atcggttctt gccgataact cattttcata taatttgcaa aacctaatac accgatggct
    11281 acgacatacg taagggaacc taaagggaca gatcctgcta gtgcaatcag aaaaataaga
    11341 ataatcagca agacgagaca ggctaagaag aatttttccg tatgccaaga aaaagcaaat
    11401 ttcaacgcaa ggtctacgga tagatcattt tgacaccact gcaaaaataa attactaaaa
    11461 acaacaagaa aaaagatact gatgattgct gctgttcctt ttaaaatctt tttctgtttg
    11521 gtcgaaagtc tgcttatata tcttttcaaa tgcttgctcc ttcatttcta tcaataaaag
    11581 aatgttgctt ctcttatttt agttgtacga aattcgaaag taaagaacgg aaagaagaat
    11641 taatgaaatc caaatattct ctttctttat ggcctttctg gtttctttaa taagcggacc
    11701 tttcgtactc cagaaatttt ttctagctgt tgtttcactt gattgagctg ttcaaaatca
    11761 gtactgtcta tgtcaatcaa tatgtagaca tgctcattct tatggttacg cgatatatct
    11821 gcgatcgcta gctcgttctc attcagcaga gaaaatatct ctgctaatat attggttttc
    11881 ttttgataaa atatagtgaa tcgaaacggc gcttggaaaa acattcgtgc ggatggataa
    11941 ttgaccgctt ctctaaccgt accgaacaaa agataatctt ttaaggcttc aactgccaaa
    12001 cgtccgctgt ctgccaaagc ttcctgagtc gatcccccta gatgaggcaa cataagtata
    12061 cggtcatttt ctaagaactc ttcttctgga aaatcagtca agtatttagc cagatgttgt
    12121 ttttccaatg cttgcataac agcatattta tcaacaattt cacttcttcc tacattgata
    12181 agtacagcat cttttttcat tttttctata ttcgcctgat cgatcaatcc ttttgtatct
    12241 tctgtcaacg gcagcatgac tacgatgtaa tccgaggtag aaagaactgt ttctaaatct
    12301 gcttgccgaa cataatccaa ctgggcatcg cggatagaat aacccaagac atccatccct
    12361 aagctatagc aacttagcgc tacttttgtg cctatcgctc caagaccaag aagaccgatg
    12421 gttttgcctt gcaattctcg tcccacataa gcacttcttt tgttttctgc ctgttctaaa
    12481 atattaggac ctgttagtgt ttgtaccata cgacttgctt cgattatcgg acgggaagat
    12541 aagagcaaac agcacaaaac aagctctttt actgcattag catttacacc tggtgtattc
    12601 atgacgatcg tcccgttttc agaagctttt tcaacgttga tcgtgttcac cccaacacca
    12661 gctcttgaaa ttgctagcaa atctggtgta agccattcat ctttcacttt cgtactacga
    12721 ataactattc cttcggctgg caaatcatct attattttga aatattcccc ttgtaacttt
    12781 tctatctctt gttctggaat agcatcaatc aaatgaacgt gatacataaa accccctcct
    12841 tactaacaag tatctcgaaa tttctgcaat tagacaactg tttaccattt gacttcctag
    12901 aagcaaaaag agcagttaga gcagagtagg ctgagtgata aaaataaggc tatgacaagt
    12961 tactgccata agccttattt tcgagagcaa aatattgagg gtgagatatc ttgataaatg
    13021 gtgttccgtt agctgacatt gataataaga ctaaatttca aaaaagttga aaagcaaatt
    13081 tcgtcaatct cttcttattt cttaaaacta agtggctttt tcacaacctc tttttatcta
    13141 ataaccactg tttccaactc aactaatttt gcccacgttt caatttgatc tgttgttaga
    13201 tttagcgaga caacggtatg atgaccgcca cctgcctgaa tccatgaatg gacaccttca
    13261 tggaaattcg gtttagtttt ccataacaca cgtgcaacag gtaaattagg tgcttcagtc
    13321 gttggttcaa aggcttctac ttcattgatc agcagtttat aatgcgtacc gaaatctgcc
    13381 atcgatacga ctaccccttc tcctgctttc ccatcaaata caagacgcgc cggatcttct
    13441 ctatctccca ttgataaagg agaaacaacg attcttggtt tcgtcgcagc aagcgtcgga
    13501 tctacttcca tcatatggga ttccaagatt gcttcttggc cactagctag ctcgtaagta
    13561 taatcttcca tgaatcctgt atctttccct cgagccatga ttttcagcaa ccgatcaatc
    13621 gctgcagttt tccagtcgcc ttccccagca aaaccgtatc cttctgccat caaacgttgt
    13681 acagctagtc caggtagttg tttcattcca tacaggtctt caaaattagt cgtaaaagcg
    13741 ttatagcctc cttcttctaa gaaacggcga ataccgattt cctgctgagc ttgtactttt
    13801 acatgttcct cccatgtctt ttcttcataa tcaccatagt cgaaggtata caattccttg
    13861 tactcttcaa ataattgatc gacttcttcg tctgatacgc gatcgattac ttgtacaaga
    13921 tctccgatac caaaataatc aacagtccaa ccaaattgaa tctgtgcttc cactttgtct
    13981 ccttctgtga cacccacgtt tctcatgttg tcaccaaaac gagccacttt tattccaaaa
    14041 ctttcattat aggctactgc aacatccatc caatcagcaa tctctttttg gatctcaggt
    14101 cgtttccagt agccaacgac gattttattt tgtttattta atcgagcatt gatgaaccca
    14161 tattcgcggt caccatgagc ggattgattt aaattcatga aatccatatc gatcgttttc
    14221 caaggaatgc tttcgttata ttgcgtagct aaatgaagca atggtttttg tagaagcttt
    14281 gtcccgcgga tccacatttt tgctggtgag aaagtatgca tccaagtgat cacacctgct
    14341 acttcttctc gataattgac ctctttcatg atttttgtga tcgtatcagc agtaactgct
    14401 aattcttgaa ggcggattgg ataaggcaat tggccatttt cattcagttc atcgaccatt
    14461 tcttgtgcat gtttctttac ttctcgcagt gcttcttccc catataaatg ctgtgatcct
    14521 acaacaaacc aaaattcttt ttctccaata ttcaacataa ttagccactc cttttatttg
    14581 ttttgtccgt aatacgcatt ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt
    14641 tgaggcagct cttctgaaaa tgaattgagc tgtctggtaa ataaattcat cttgcatact
    14701 tcatctagta cgactgcgtt cattaccgca ctttgcgcat ctttccccca agtaaatgga
    14761 ccgtgtccgt gtaaaagtac ccctggaatt gctaagggat caattttgcg ttctttgaat
    14821 gtttctatga taacttttcc tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc
    14881 aaaaatcgag cacaaggtac cgatccataa aaagtatctg catgcgtcgt ccccatcgca
    14941 ggaacatcca atcctgcttg tgcccagatc gtcgcccatg tcgagtgagt atggacgatt
    15001 cctccgattt gaggaaatga acgatataaa acagcatgag taggcgtatc cgaagaggga
    15061 ttgagtttac cttcaatgat atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc
    15121 atctcttcat aactgactcc gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa
    15181 gcgctcacat ttccccatgt atatttgacg agtccgtgtt taggcaagtc aagatttgct
    15241 tggtatactt cttctttcag ttgttccagc attttctatc actccttttt cttgcaattg
    15301 atgaatcgct gttttttcaa tgtcgatccc ctcacggtaa cgtctcataa atatctgata
    15361 gcctgctatt tcttctgctg aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc
    15421 ttctgccaag aagttttcta aagacttccc atgtcgatcc atcatatagg ctgctaataa
    15481 cgcgattccc cacgctccac cttctccggc tgtgtccatc actgtaactg gtgcctccat
    15541 agcagatgct agaatccgct gtccaacttc tggtgtttta aaaatccccc catgccccac
    15601 taaacgatca atttggacat tctcagattt caatatatcc attccgattc tcattgcacc
    15661 aaaagcactg gctaaatgga tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt
    15721 acgtacaaat aatggccttc cttcatttac tcctgtaatg ttttcaccgg aaaaataacc
    15781 ataagaaagt aatcccccgc aatccgtatc gccttctagc gctttgttga ataataccgt
    15841 gaataattta tctctgctta tctccatacc caaagaattg gtaaattctt caaaaatact
    15901 gacccaagca ttgatatccg aagagcagtt attcgtatga accatgccta ctagttctcc
    15961 tgaaggtgta gtgaccatgt cgatttccgg atggacattt tctagttctt tttctaatac
    16021 gatcatagcg aaggcggaag taccagccga aatgttccct gtccctttgg ctacactgtt
    16081 cgtagcgacc ataccggttc ctgcatcccc ttctggcgga caaaccggga ttcctggtct
    16141 caaatttccc gtagggtcga tcagataagc ccctgattcg cttaacttgc cagcttcttc
    16201 tcctgctact agaactttag gcaaaatgtg atccaagtca atcgctacgt gcgctttttc
    16261 gattaactga ccaaaaatat ttttcatttc ttgatggtag gttttcgttg aaggatcgat
    16321 aggaaacatg cctgatgcat ctcctacgcc tagtactttc tcaccagtaa gctgccaatg
    16381 gacataacct gcaagcgttg tcaaaaaatt aatttctttc acatgttctt ctttattcaa
    16441 aatagattga tacaaatgag cgatactcca tctctgcgga atattgtatt gaaatttttc
    16501 cgttaatatt cgttctgctt cttcagtgat tgtatttcgc caagtacgaa atggtactag
    16561 taactgttcc ttgctatcaa atgctagata accgtgcatc attgcactga acccaatcga
    16621 cccgattgtc gtaagattct cgccatagat ttcgaatact tctgctgcca tttttcggta
    16681 actgacgcgc agtcctttcc aaatatcttc taatgaatag gtccagatac cattttctag
    16741 tttgttttcc cactcataac taccagcggc aataggagta aaagatgaat caatcaatac
    16801 agctttgatc ctagttgatc caaactcaat ccctaaagat gtacgaccat ctatgacatc
    16861 taacatactt tgcgcattta cttccttcat aatgatttaa ctccctcctt ctcgtcaaac
    16921 ctgatcaaac cgtcttttta gtagcgctta caatgattat tgtatacttt tgtacgtaca
    16981 tgtcaagcag ttatttacaa gaatacaata aaaaacactt gttttgtacg tacataagtt
    17041 ataaaatgaa attgcttaca aaatctgatc aaccgccttc tcgaaattct agaaggagag
    17101 aatacttatg aaaaaagaaa aaaaagtttc ctcatcgttt atttattttt ttggcgcatt
    17161 tggcggcatt ctatttggat atgatattgg tgttatgacc ggcgccttac cttttttaca
    17221 gcatgattgg ggtttggcag gtaaagcttc tttgatagga tggatcacgt cttcggtcat
    17281 gttaggtgcg atccttggcg gctctttatc tggtcttctt tctgataagc ttggacgacg
    17341 aaaaatgatt cttctttctg cacttatttt tatggctggt tctgtccttt ctgcatctgc
    17401 ccctcacaat ggttcttatt ttctgattgc agcaaggatt cttctaggtt tagctgttgg
    17461 cgctgcatct gccctagttc ctgcttatat gtctgaaatg gctcctgcta gactaagggg
    17521 aagattgtca gggatcaatc aagtgatgat tgcttctggc atgctccttt cctatgttgc
    17581 agattatttg ctaaaagggt tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc
    17641 tgctgtcccc gcgctgattt tatttttcgg tgttttagct ctaccagagt caccgcgttt
    17701 tcttatgcaa tctggccgct tggaagaggc aaaaagagta ttgaactata ttcggacacc
    17761 aaaagaagct gaacaggaat tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac
    17821 cggaacttct tggcatactt tgtttttaga aaaatatcgt tccttagtca ttgccggtat
    17881 tggtgtagca gtattccagc aatttcaagg agctaatgct attttttact atattccgct
    17941 gatcgtagaa aaagcgactg ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca
    18001 aggaatcatt ttagttgctg gttctttgct ctttttggtt attgcagaca agttcaatcg
    18061 gcgaacttta ttgaaaatag gcggtagcgt gatgggactt tctttcatcc taccagctgt
    18121 tttaggaact gtactggatg ctcatacaaa ttcgttgttg attctcttgt ttttatgtat
    18181 ttatgtcgca ttttattctt gcacatgggc tccactgaca tgggtaatcg taggcgaaat
    18241 attcccacta gctgtccgcg ggcgagcatc tggcctagcc tcttctttta attggattgg
    18301 ttctttccta gttggcttgc tttttcctgt gatgactgct tctatgtctc aagaaatcgt
    18361 tttcggcatt tttgggatca tctgcttttt aggggtttta tttattcaag agatcgtacc
    18421 agaaactcgt gggaaatctt tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc
    18481 taaacgtatt tctatccatc attcttaaag aggttgtgac agaagtggtc agcttcaaga
    18541 aataagaagg aaccgcttag tttccagtca caaggaacaa tttcaaaaaa cagcttctca
    18601 tgtttgatga atattgtgac ttgtgaccag ttggtaggag aacaccgttt agtggagagg
    18661 tggtgaaaga aacgttcagc cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag
    18721 taaccgtagg agcaataaga ggcggtaaaa acccgtctct tatttttcgt tttctttcac
    18781 tgtttcccgt tcaactagta caggttcata gagaatattt ggctgtgcct gtcctttttc
    18841 aatcgttgtg acgatccacc gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa
    18901 tgttgtcaat tttttattcc ctaaatggct taaagaagaa tcgtctgttc ctacgatcga
    18961 taggtcatct ggaatatgat agccattttc tgtcaactta tctagcatta aactagctat
    19021 ttgatcgtta tagcaaatga tgccatctaa agcttgttct tctttcaacc gttgtactgt
    19081 tttttcagcg attgtttctc gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa
    19141 acgcacatta tactgttcac acgcgctgat aaaacctttc atcctgtatt ttccttgaag
    19201 atcgtcgatt tttgtgatga acaacagacg ctgatgtcct ttttttatca aatattctgc
    19261 tgccataaaa ccgactttca catcatctaa acaaatataa gaggcattta actcttcata
    19321 agcagcattg atcatcacca tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa
    19381 gtttgggtta tactgattac ttttcgtagg ctcaacgatc aaaccatcta ccccataagc
    19441 aatcattttc ttcaaacact ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag
    19501 caatgaatac ccagattctc gtaattcatt ttcgattcct cggataatcg acggaaaaat
    19561 ataatcagag agatatgtgg tgatgacacc gatcgttttt gttctgttca atggtgtttt
    19621 ttctttctta tagctgtcat ctacatatgt gcccgaccct ttttctttac gcagatagcc
    19681 ctcatttacc aacacagcga ttgcttgccg aatcgtatgt ctgctgacgt catatatttc
    19741 ttgcagcttg aattctgagg gaatggttgt atttacttcg tattcctcac gaaggatctt
    19801 ttgttttatc tcttctgcaa tatcttgata ttttgccatt tgccttgccc ctttttattt
    19861 gtacgtacat atatcataac gagtctgcaa ggtttattca agcaaaaatc aaggtttctt
    19921 gtgctcataa ggcatacgga acaggttcac caaattctgg aaatccttgc tcattccacg
    19981 taaagcattg cgcgttcgcg tgccgattag gattgtctaa cggatcccct ttttggttct
    20041 tctctggtcg agcatgatag atcaaaatat caaagcaccc gtcttctgaa accgtaaacg
    20101 agttgtgacc aggaccaaat tgcttatttt tttcagaaga aacgaatact ggctccgata
    20161 atttatgcca tgattctttt aataaaagat tcttgtgctc atcagcccac agcaggccca
    20221 tggcatagtt ttcatctgtt gcactaccag aatacgtaat gaatattttc ccattgcgag
    20281 taaggactgc tggaccttca tttactgaaa aaccccgttt ttcccattca tactcaggta
    20341 tagaaaggag gatctgcttc ccctttaacg tccaaggatt atccatttcg gatagataaa
    20401 gattagaatt cccagtaatt tcaggatctt gttgggccca cacataatat agctttcctt
    20461 gagaagagaa agttgttccg tctaaactga aagtttccct tttcgttttt atttgtccct
    20521 tttctatcca atctgtattc attggatcta tatgctgatt ttcaagtacg aacatgcggt
    20581 gatgatgaga ttcatcacgt atagttttat gattgcttgc agcaaagtaa atataccatt
    20641 ttccattgat ataatggact tcaggtgccc agatcaattc actcatcggt ccttcttcat
    20701 gagcctgcca tacaatcagg cttgcagcat gttctaattc attcagtgac tttgcccttc
    20761 ttaattcaat cacttggtag cctggaaccg atcctgtaaa ataataataa ccatctgtat
    20821 gtttatatac ccaaggatct gcccgttgcc gaacgatagg attattataa agtgtcttca
    20881 tcataacaaa tttcctcaca ttttctttat tctaattaca ttccaagagt atttttctat
    20941 ccctacattt aattcgtcat gtttttctat tgaaaaatag tttatttcag gttttatttt
    21001 ttctggttct tcacgtgtat ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc
    21061 tccttgatct agcaaattga aatcatgttc aatcgttatc ttttgttgtt catttgtgcg
    21121 attgatcaag aaaatagtca gctgattgcc gttatctacg atcacactgt ccacataagg
    21181 aacatttttt atcttttcac aatcataaac agggcaaatg atttgttgtt tcaatacttg
    21241 acctttagca tatttcgata agtgttgcat cacataataa gttggattcc tccatgcttg
    21301 tcctttagca tctgtcagta ttaaaggtat tgtgtttact aacaatgatt gacaactaat
    21361 ctttacgcga tctgcgtgtc gtaaaatagc cagccctaat gaaccaaata ataatgtatc
    21421 ttccatagta aagtaacacc aatcgatggg actaccgact tcaaaatccc tatgtctttt
    21481 ttccggttgg gcatgtacat tccattcatc aaacgctaga tacattgttt tctcacttct
    21541 caaatatcct tttacataat cacaagtagc aacgatttct tcaatttgac gatcgaatcg
    21601 ataagctttt gcaaggtatg tcgctgtatc atcacgctca tttttaggag gtttagtcaa
    21661 gtcttcttca tcatacttat caatatagtt atgcaaagct aaataatcta cattctcata
    21721 agcttcttct aatgcgatac gatcccattc agggtacgat ggtaaacgtg gcgtagagct
    21781 tccaactaag attgtttcaa ttgaatcatc cactaacttc atgacttttg aggcttcatt
    21841 tgctaaccta ccatattcat aagcactctt agcccccact tgccatggac cgtctagctc
    21901 attccctaaa caccataatt taacgccaaa aggctttttt tgcccatttt ttattcttaa
    21961 atcactccag aaggttcctt ttggaaaatt acaatattct actaaatttt ttgcttcatc
    22021 aattcctttt gttcctaaat tcaccgtgaa tatcggtttc gcttgtacat gactgatcca
    22081 tttaaaaaat tcgtggagtc caaaagaatt tggttctata cctcgccatg ctaaatcaat
    22141 tttttttggt cgttgttctt tcctacctac agtatccacc caatcataac cagatgtaaa
    22201 gtttcctcca ggatagcgaa tgacacctaa ttctaattcc tttacataag agaggacatc
    22261 ttgtctaaac ccgtcaccat cagctgtttc atggcccggt tcataaatcc ctgtatagac
    22321 gacacttccc atatgctcaa caaatgagcc aaacagccga gaactgatct ctcctaccgt
    22381 aaaatcctct ctgattttta ctttcacttc ttcgtccaac agctttccct acctttcatt
    22441 tcctatagtc aagataatag atacaagttt ccatacgcca ccagcaaaga taaaaataaa
    22501 aggagggaaa agaaatatga gcagtacaaa tcctaataac aatacgcaac aaagaatatt
    22561 tctcaaaaaa tcaaaaaata ctttccatgc actttgttca aaaatttgta aaaatgtgat
    22621 atctttgttt tcagaaatca catatatcca ggataaaaga aacatggaat aaataagtaa
    22681 aactacatat ccactaattg aaagtacgat tgtctgttct tctaataatt gattaacaag
    22741 aaaataaata atgatcgtta acagactaag gaacaagttc ttaccaaaat gttgctttat
    22801 tccttgaaag aaaaaataaa tgatatttcc tgatccctca cctttccatt gcgccattac
    22861 ataaaaaaca gcacatgtag caggcacgat agtaataaca ggcaaacaca cgattaccca
    22921 gagaatacct aataagatgt aatcagaaac cacaatcaac tgtccataaa gtttagtctc
    22981 aactattttc atcttcctca ctctttcatt ccagacatag ctgttccttg aacaaaatat
    23041 ttctgtgcaa aaatataaac cactagtaat ggcagcattg aaataaccgt tccagccatt
    23101 acaggtccat aaaaagaaat gttctgccct gtaaataaag ctaaccctgc tggtaaagtt
    23161 ctcatttttg aactacttgt caatatcaat ggataaagca agtcattcca actattcatc
    23221 agcgtgaaaa tccctaatga taaaagagta ggtttgctca atggcaacat gattttcaaa
    23281 aaaatattaa actcacttaa tccatcaatg cgtgctgcct cttccaaaga atctggtaaa
    23341 gtaataaaaa aggaacgcat catgaagata ccaaatgcag ttgtcatacg aggaatgatc
    23401 aaacctgcat aagtatcaag catgccaagc aaattgactt caataaatag aggaatcatg
    23461 aagacttgga atgggatcat cattgtcagc aaaacgaaat agaacaaaac tgattttcct
    23521 ttgaaacgca tacgagcaaa tgcatacccc gcaagagaat caaagaatac agaagtgatc
    23581 actgtccctc cagcaaaaat cactgtattt ttgatgtaat ctaataaagg gatcgttgtc
    23641 caaaccttaa tatagttatc tagggtatag ctatctgcaa atattctagg cggaaatgag
    23701 ataatgtctt tttcgtgttt aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata
    23761 accaacaata taactagcat actaatcgtt cgaatgattt ttttaccact aactgctttt
    23821 cgactattca cagtaactgt aatcgagctt tctggtgcca tacaggtttc cctcctattt
    23881 catttgtttt tctttccgtg acatgtacac attagtggag atagctatag ttgcaacaat
    23941 gataaacaaa accgaagaca gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc
    24001 tcgactgtaa atatattgaa cagctgtttc tgtcttaaat tgtgggccac cagcggttgc
    24061 aacatatact tggtcaaaca cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc
    24121 taaggaggga acgatctgag gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc
    24181 atccatttga gcagattcat acaaagaggg agagattccc tgaatagcag tcaagagaat
    24241 cgtcatagta acaccaaaat tcttccaaac agtcatgatg gctaccgtcg gcatagcaag
    24301 ggttggatcg cgaaaaaatt gagggatcgg caagccgact tgtgaaaaca agtaaggaat
    24361 cgcccctaca ttcggatcaa gcaacataga aaaaataatc gcaattgacg tcaatgaaca
    24421 aataactgga atgtaaaatg tcgaacgaca aaaacgattg aatctggtat ttttagataa
    24481 tgctactgct gctaataaac caacgataat ttgtgttggc gtttcgagta cggtgaaata
    24541 taaagaatga atcaacgaat taactgctcg ttcatcacta aatatacgtg tgaaattttc
    24601 aaaacttaca aaatttcttg atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa
    24661 tgttcctaaa agcggtatga cagtaaataa taataaaact aaaaaagatg gagttaaaaa
    24721 caaatacgca gcacgatcag gacgattcca atatttggtg aatccgttca tatagtccac
    24781 ctcatctttc attttgataa aatatacaat cttggtttaa acgaatctga ataagatatc
    24841 cgaacaatcg ctgtgatttt tgcaataaca cctatctgca aatactaggt cgatcattca
    24901 gatatctgta tcttgccaac agtctatcct gtataaagtt ctgtactatt tttgcagtaa
    24961 ttgattgatg gcatcatctg catcgttcat gagtgtctca ggatcttctc ctgctaataa
    25021 tttttcaatc agtggattga tgatatcgtt attgatcgca gagatttggg taaaacctgg
    25081 taaatatggc tctgcatagt ccatttgttt cgataattca gatacaatag gatcattttt
    25141 tacttcttca tcttttgcta ctgaatccaa gtaggcagga aaaccatttt cgatactcca
    25201 ttttttacca atttcagttg tattccaata tttcaaaaac tcatagacag cttctttttt
    25261 attattatct gtacttgccg gaatggcata tcctacgcca tctaaaatag ctgttttttt
    25321 gtctgaatca ctcccttgtg gtaaggtagt cacattataa tcaatctcgt ttgctttcaa
    25381 tccgttattt aaccatggcc cattgatttc aatggctagt tgaccagcat tcattaaatt
    25441 gtccatttcg gcgccagaaa tcgattctgg accagtcttg tctacatgga tcattttttg
    25501 gatcgctttt aacgttttaa ggttctcagg agacgcaaat tcagacttag tataatcatc
    25561 gttcactaat ttaccgccat ttgctaacat ccagttatat aacggtgcag ttccatcctt
    25621 attgaagaca aaacctgata catttttact actatcagtt aattttggtg ccatttctgt
    25681 caattcttcc caagtagtag gtggttgttc agtatctaat ccagcttgtt taaacaaatc
    25741 attattccaa tacatataca tgccttgtac ctgcatgggg acaaaatact gtttaccttc
    25801 tacttcacct aattcaatag ccgtttcttt aaaatcagat ttatctactc catcatattc
    25861 ccagaaatcg tctaatggtt gtaccgctcc gttttctaca tactgtgcaa aatctggata
    25921 atttaatgca ataaagtcag gtgctttttt agaagaaatc gctgtaggaa gtttttcatt
    25981 caaattggcc caagtcatga tatccatttc aattttgatg tttttatcat ttgttttatt
    26041 aaattcatta acgatttctt gcaatatttc accatcagat gcagtaaacc cattccaaaa
    26101 agtcaaagtc acttctttat cagaatcaga ttctgctgaa cttccgccac cgcaagctcc
    26161 taaaatacct gttgcagcta ccaacaaaga gccaattaac cattttttac ctttcatttt
    26221 ttgttcctcc ttcatctgat aaacgacatc tgaccacatt ccaagatagc ggtttcaata
    26281 aacaattgat tttcccatct tcagctttta catttgttga atgacttggt tttacttgtt
    26341 cacttttagg aagattagtt gcttttgtat caaatccact catttcagaa aaatcaatca
    26401 ctccctctaa tgataattca gacaagtgaa cagttagatt catttcttct tctccacggt
    26461 taactgcaaa tatgacaagt tctttgtcat ttattacggc tatactttct aaatacggca
    26521 cttcttcaaa atcttccgtc gcatagtttg ctgaacgaat ttgtgggctt aacacctctc
    26581 cttgtccata cacagcagct tgcataaatg gataatagat cgtctgtctc caagcttctc
    26641 cgtttgtttc tgtcctgatt ggtgcaataa catttaccaa ttgagcaaga caagcaatct
    26701 ttactctatc tgcatgtttc aataaagtga ttaatagaca gcctaatagt aatgcatctt
    26761 caaaattata gttatcttct agtaaaggag gagcaatctg ccaaggcgct gcttgctcat
    26821 cttgttccgc tgaatgatac caaatattcc attcatcaaa ggacaggttg atctgcttct
    26881 tactatgttt cttcgccttg actgtatcgc acatcgctgt cacttcagaa atgaaccgat
    26941 ccatgtctaa ggaacgtgca agataatgag aaagatcatt tttttggttg ccataatatt
    27001 gatgcagaga caaataatct atttgatcgt acgcttgatc aagaactgtt aactcccaat
    27061 caccaaatgt aggcatttgc cgattcgaac ttccgcataa aaccacctca attgaatcat
    27121 ctacgagttt catcgcctta gccgtttcct ctgctaaccg tccatattct tccgctgttt
    27181 tatgtccaat ctgccaagga ccgtccattt cattccctaa acaccatgtc ttaattccaa
    27241 aagggctctc ttgaccattc gaacgcctta aatcactcca ataagttcct ttaggaaaat
    27301 tacaatattc gactaaatta cgagctgcat ctactccacg agtacccaga ttgacagcca
    27361 tattgatttc ggcccccaca tgctgacacc agttataaaa ttcatgaatc ccaacttcat
    27421 tcgtttcaat tgtccgccaa gctaaatcca accttctagg tctatttgct atgggcccaa
    27481 tactgtcttc ccaacgaaat cctgacacaa aatttccacc aggatatcta atcatgggaa
    27541 tgttcaattc ttttaccaag tgaatgacgt cttggcgaaa tccactttta ttagctgatg
    27601 gatgatctgg ctgataaatc ccttcatata ctgctcgtcc catatgttca ataaatgaac
    27661 tgtacaaccg cggatcaact ttgcctacac gcttgacact actaatcaac attgtggctt
    27721 ccataactga cctcctttaa tttatacatg aataatgcac ctcgttgaaa gcgttg
//
LOCUS       DADVXB010000022        27739 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.022, whole genome shotgun sequence.
ACCESSION   DADVXB010000022 DADVXB010000000
VERSION     DADVXB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.022"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(53..2134)
                     /gene="cadA"
                     /locus_tag="KB902_000743"
     CDS             complement(53..2134)
                     /gene="cadA"
                     /locus_tag="KB902_000743"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6807589.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(2658..3017)
                     /locus_tag="KB902_000744"
     CDS             complement(2658..3017)
                     /locus_tag="KB902_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBB6807590.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(3047..3388)
                     /locus_tag="KB902_000745"
     CDS             complement(3047..3388)
                     /locus_tag="KB902_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807591.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(3385..4059)
                     /locus_tag="KB902_000746"
     CDS             complement(3385..4059)
                     /locus_tag="KB902_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6807592.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(5112..6410)
                     /gene="asnS"
                     /locus_tag="KB902_000747"
     CDS             complement(5112..6410)
                     /gene="asnS"
                     /locus_tag="KB902_000747"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBB6807593.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(6450..7640)
                     /locus_tag="KB902_000748"
     CDS             complement(6450..7640)
                     /locus_tag="KB902_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6807594.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(7661..8188)
                     /locus_tag="KB902_000749"
     CDS             complement(7661..8188)
                     /locus_tag="KB902_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBB6807595.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(8235..11024)
                     /locus_tag="KB902_000750"
     CDS             complement(8235..11024)
                     /locus_tag="KB902_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6807596.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(11171..11371)
                     /locus_tag="KB902_000751"
     CDS             complement(11171..11371)
                     /locus_tag="KB902_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6807597.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(11824..12144)
                     /locus_tag="KB902_000752"
     CDS             complement(11824..12144)
                     /locus_tag="KB902_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807598.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(12647..13765)
                     /locus_tag="KB902_000753"
     CDS             complement(12647..13765)
                     /locus_tag="KB902_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807599.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            14236..15543
                     /locus_tag="KB902_000754"
     CDS             14236..15543
                     /locus_tag="KB902_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBB6807600.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            15664..16863
                     /locus_tag="KB902_000755"
     CDS             15664..16863
                     /locus_tag="KB902_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6807601.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(16890..18158)
                     /locus_tag="KB902_000756"
     CDS             complement(16890..18158)
                     /locus_tag="KB902_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBB6807602.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLFYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPILQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(18322..18969)
                     /locus_tag="KB902_000757"
     CDS             complement(18322..18969)
                     /locus_tag="KB902_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBB6807603.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(19378..19881)
                     /locus_tag="KB902_000758"
     CDS             complement(19378..19881)
                     /locus_tag="KB902_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6807604.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(20004..20768)
                     /locus_tag="KB902_000759"
     CDS             complement(20004..20768)
                     /locus_tag="KB902_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBB6807605.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            20876..21151
                     /locus_tag="KB902_000760"
     CDS             20876..21151
                     /locus_tag="KB902_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBB6807606.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            21816..22766
                     /gene="yidC"
                     /locus_tag="KB902_000761"
     CDS             21816..22766
                     /gene="yidC"
                     /locus_tag="KB902_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6807607.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            22870..24186
                     /locus_tag="KB902_000762"
                     /pseudo
     CDS             22870..24186
                     /locus_tag="KB902_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(24887..25087)
                     /locus_tag="KB902_000763"
     CDS             complement(24887..25087)
                     /locus_tag="KB902_000763"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807608.1"
                     /translation="MAEMHDHLLHSICERTGLSEEEVNQKLMEISEAMNKGVDFSMNQ
                     LDDFLAQHMKDALASDAADSVE"
     gene            complement(25437..25784)
                     /locus_tag="KB902_000764"
     CDS             complement(25437..25784)
                     /locus_tag="KB902_000764"
                     /inference="COORDINATES: protein motif:HMM:NF019886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6807609.1"
                     /translation="MDHLHDHDAENRLESNYARYLGGIEQTIEDSYTQDCMMSYTPDI
                     VEKIAPTDFKKMERKRLQEEIQKLTFNQRKVIEHYYFLNKNQQQIARDLRMSHAEITK
                     TLKRAFAVMKEVY"
     gene            complement(26179..26556)
                     /locus_tag="KB902_000765"
     CDS             complement(26179..26556)
                     /locus_tag="KB902_000765"
                     /inference="COORDINATES: protein motif:HMM:NF025104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807610.1"
                     /translation="MFFLAFLYLYIANVKYFSKWPLLLFWIISCVLLLVKNAVFQFLL
                     KKIGSKSHTRVLVVENGNLAKEYGLAMLSDPDADANIIGYVKDRKKEDILLEEPGFAN
                     YGDGLAKLKYFGRISDVQDVIVK"
     gene            complement(26580..26903)
                     /locus_tag="KB902_000766"
     CDS             complement(26580..26903)
                     /locus_tag="KB902_000766"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807611.1"
                     /translation="MIDRRDDSDRCWSIRYYYKGRINEIIKERFWNTVFDCIGDAASI
                     FVAYLLAMFICYHVLEAAPGINMLSVPYLMMAALYSILIADFLRIFRATNKTYFRKYQ
                     NGFLK"
     gene            complement(26965..27441)
                     /locus_tag="KB902_000767"
     CDS             complement(26965..27441)
                     /locus_tag="KB902_000767"
                     /inference="COORDINATES: protein motif:HMM:TIGR01670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807612.1"
                     /translation="MSQIKFLVMDVDGTLTDGKIYMGECGEIMKAFNIKDGCAIHDIV
                     RAHNIEPIIITGRRSKILENRCKELGINILYQGIDNKIEKLLEITSDLSTVAYIGDDI
                     NDLSCMHPVKSAGGIVACPHDAVKKVLEISDFIAEHDGGNGAVREFVEWLVDTQNN"
     gene            complement(27458..>27739)
                     /locus_tag="KB902_000768"
     CDS             complement(27458..>27739)
                     /locus_tag="KB902_000768"
                     /inference="COORDINATES: protein motif:HMM:TIGR00022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBB6807613.1"
                     /translation="RMYESHLKYLDIQCILLGCEYIVVESISNLQIEVDYSADKDIVF
                     YSNSIVGNCVLLEGGKLLLLTPEDAHMPCIRVNESAKVKKAVFKISINY"
BASE COUNT         8078 a         5957 c         4887 g         8817 t
ORIGIN      
        1 attaagaaaa ggatataaaa aaaagaggac gttcattcgt cctcttcatt gatcaacgtt
       61 tattttttac atgcaagctt cgcatggcat tcaaaacagc taatactgtc accccaacat
      121 ctgcaaatac tgcatctccc attgatgcaa aaccaaaagc acctaaggca agtaccaaaa
      181 tttttatccc aatagcaaag acaatgttct gtttgacgat tttcaatgtt ttctttgcta
      241 aatggattgc ttctgcaatc ttcgatggtt gatcattcat gatgactaca tctgctgctt
      301 caattgcagc atcgcttccc aatccaccca ttgcgattcc tacatctgct cttgctagca
      361 ccggtgcatc gttgattcca tctccgacaa atgcggtctt tttattgttt ctttgtaaga
      421 tttcctctaa ccgctgcact ttatcttctg gaagcaattc gctatatatc ttgtccacgc
      481 ctacttgctt cccgatatga tcagcaattt ttttcgaatc gcccgtcaac atgactgtgt
      541 tcttcacacc agcctttttt aattgaacca atgcgtctac ggcatcttct ttcaaggtat
      601 ctgcaataac aagataacca ctgtaacttt gatcgatcgc tagataaagc aatgtaccga
      661 tttcttgact tgaaggaaaa gagatttcaa atctttccat caatttgtga ttacctgcta
      721 atacttgttt gccatcaact tcagctaaga tcccttcacc tgcaaattct tggatattag
      781 ctgttggtaa aagcggacct gcgtagcctt ctaaaacaga ttgagcaatc ggatgtgtag
      841 aaaactgttc tgcactcgca acatattgca tgaatatctt tggatcgatt tttgtatcga
      901 tcgtctggat cgaaaagtca cctttcgtta atgtgccggt tttatcgaat accactgtct
      961 cagtttgtgc aagcaactcc aagtaatttg aaccttttac taatacaccg attttacttg
     1021 ctcctccgat accgccaaag aaactaaggg gtacggagat cactaatgca catggacatg
     1081 agatcactaa aaatgtcaat gctcgataga tccattcaga aaacgccgct ccagaaacaa
     1141 caagtggagg taaaacagct aataaaacgg ccaatcctac aacgactggt gtgtaatagc
     1201 gcgcgaattt agtaatgaaa ttttcagctg gtgctttttt actgctggca ttttctacta
     1261 attctaataa tttgctgata gtagaatttt cataagattt ttctacttga actaaaaatg
     1321 gtttattttt attgataaat ccacttaata ctgtttcacc aacatataca gatttaggga
     1381 ctgattctcc tgtaagtgct gacgtatcga ctaatgattc tccttcgatg atcgttccat
     1441 ctaacggtac acgttcacca ggcttcacaa gtacaaactg accgatctgc acgtcttcag
     1501 ggttcacggt catcaatcct tccgtcgtct gcacgtgagc tgtttctgga cggatcgcca
     1561 tcaattcgcg aatcgatttt cttgaatgac tgactgccaa tccttggaaa tactcgccga
     1621 tttgataaaa tagcatcact gctacggctt ctggatattc accgatcaac atagcgccaa
     1681 tcgtagcaac agacataaga aaattctcat caaagatttt tcctttgacg atattcatca
     1741 ctgccttctt cactacatca tatcctatca gcagataaat caataaatac cctatcaagc
     1801 gaattggttc attaaaatca aataatagca ataaagcgat acctgcaagg gaaaataaaa
     1861 tccggaacag cgtatttctc tctttttcat ttccatgttc agatactttt tccttatcta
     1921 tttctgttac tttgacatct ggttctaatt ccttcactac tttttttatt tcttgttcaa
     1981 tcgtagccaa atgatcttcc tctgcgtcaa tcgttagttt tccagaagtg aagtttaccg
     2041 ttgcttcctt gactccattg atcttctgaa ctcctttttc gattttcatt gcacagttcg
     2101 cacaatctaa accttctaat ctgtaacttt tcattttaat gacctcctcg cctcaacata
     2161 tgaatatctc ttcataacta attataaatg aacggttatt catatgtcaa ggtatccgaa
     2221 agaaaaaatg aaaaacatct gcatcggaaa atttcttcca tacagatgtt ttggcttatt
     2281 ctttcttttt cttttcgatc attgccactg ctcttatcca acccgcactt gccttcttga
     2341 tcttgacagg atagcaacta agtttgaagc ctgttgctgg caatttgtct aaattcatta
     2401 atttttcgat aggacaatat cttttttcaa tccctgcaaa atgtccttcc cagatattcg
     2461 aagctccact acgctttcaa aaatatagaa agagttcttt aatgaaaatt atttcaactt
     2521 tccataaaca gtaaccccat ataaataaaa gacgtaaaag tcacatggaa gaacttatac
     2581 aggagaacgc atagagtcag gtgaaataca tgtatcccac ctgactctat gctttatcta
     2641 acctttatta ttctctttta tacaatttct gcaccgaatg gcatcaacgc caatcgagca
     2701 agtttgaaag attgcttggc aaaaggtatc cctatgatcg tgatacatag aaggatgccg
     2761 ctgacgacat gtgcgagagc aattggtagg cctgaaacga tcagccagat gatattaaca
     2821 atcaatgaca tgccagactg gtgataaatt acttctttgc caaaaggcgc aaaagaaagg
     2881 gaggcgatct taaaacattg cataccgatt gggataccta tgatcgtgat acaccaaagt
     2941 atccccgctg ctaaccagct aagaccaccg attagtccgc cgaatataaa ccagatgaca
     3001 tttcctaaac aactcattgt atttctcctt ctattactgt ttttgattaa aactgggcaa
     3061 aaaatgattt tattcttctt tttttagctt ccagtatcaa atattctgca aatttttttt
     3121 ggatttcttc cgtattttct tttgttacta atgtgtgttg gattagtttt cctgatggtc
     3181 gctgatccaa tcgttcttct gactgttgca cgtccgcttg cgcaaatccg ataatccgtt
     3241 tttcttttgt tacagcaacg agcaatagtt tattcttatc atttaggtca gctgccgttt
     3301 ttgcttttac gaatgattct ggatgatcag taatcagctg attgatttga ggtagatctt
     3361 cttttactgc ccaccgtatt tccatcattt ctcacttttc tttcgctcat ttttatctcc
     3421 actaaaaaaa tcgactgcgg caattgcatc tatccagctt tgtgcaatga tctcatgtcc
     3481 gccaatcgtt gggtggaccc catcttctct tgtatatttc gaaaaaccat aaacaatccc
     3541 taaagcattg aatataccat ctaaaggaac cagcaatgcg ccatattcct tagcaagttt
     3601 acgaacaatt tggattttag ggtctaagtc tttacgccag ccatgacggt cgtcggttat
     3661 aggaagtaca aacggctcca tcaagatgat gttgcagatt cccactgttt gaagttcatt
     3721 tagtaatttt cgataaacgg attcaaattg ctgagcagat ttctcagttc cgaatatagc
     3781 ctgatcgcta gtattatgcc aggtatcatt gattccgatc aaaatcgata catagtcagg
     3841 ttgtaaagct aaacaatctt cttgccagcg tacttgcaga tctgcaattt tgtctcctcc
     3901 tatcccacgg ttcatgcatt caaattccat cgttggatat tgggagatta gttttccggc
     3961 aatcaaaagt ggataacctt tacctagatc agttgcttct gctcggtctc ttcctgcgtc
     4021 tgtaatgcta tcaccgataa ataatatacg ttttttcatt tgtcaaaaac tcctttttga
     4081 ataaaacgat gattttcttc cttatattat cccataagcc ctatcaagac gaaagagaaa
     4141 atatatgtat aaaaaatgac accagcctag tcccttcaaa caattgaatg aacgctcatc
     4201 aagtgtctag ttttttatgc tatttttttc ttaacgtgcc ggattcccct tgattccttc
     4261 gttgtttggt ccagagagat cgatcacacc taagcttccg tcaatcagac cactgatgac
     4321 gccatcagaa catatattta taggctcatc taagacttct agtaaatgtc cctttactaa
     4381 tatctcttct agattgcttg ggatagattg gtcataactt tatctggtcc gatgatttca
     4441 agggtgaatt gaacttacat atggattatt gcatgctgaa aatacggacc tactccatct
     4501 tcgaatgtta ctattagttt gttttcaggt gctagatgct gctttatttc aacagcagaa
     4561 gcatcatcaa atcagatttc catttgaatt accttctttg taaatgtttg attgattgcg
     4621 atttcgttat agaaccttgt gaatcaaata gcaatttctt ttgctttctt ctcttgtctg
     4681 ctggaaactt cctttatccc gtattttaaa aaaagaactg cgagagttcg cagttctttt
     4741 ttagaataaa cggtgctctc cggccaactc ctcggtcaca agtcacaata gtcatcaaac
     4801 atgaaaaact gttttttgaa attactcctt gtgactcgga gctgaacggc aggcgcacaa
     4861 cctcttcctt aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa
     4921 aatgtggaaa gccatttcca caaaattttt cttaatactc gaaactaaac agctttttca
     4981 caacctctcc actaaacggt attcaaaagc ttacatctgc ggtaataagt cccgccaatt
     5041 caaaaacatg aacagctgtt tttgcttggc tgttctaatt acttgatgca gaacagcttt
     5101 ttcatcacct cttatggata aattcggttc aacaaacgtg ggaatggaat agcttcacgt
     5161 acatggtcga taccagcaat ccaagtgact gttcgttcaa gacctagacc aaaaccagag
     5221 tgcggaacag aaccgtattt acgtagatca agataccatg aatattcttt ttcatccaaa
     5281 ccgtgattac ggatttgttc tagcaagaaa tcatagtctg ttgcccgttc gcttccgcca
     5341 ataatttcac cgtaaccttc tggtgcgatc atatctgcac agatcaccac gtcttctctt
     5401 gttggatgtg gtttcatgta gaatggcttg atggcttttg gatagtttag gataaagaca
     5461 ggctgttcga atgaattcgc aatgaacgtt tcatgaggtg aaccaaagtc ttcgccccat
     5521 tcgatgtcat caaatccatt tttcttcagt aattcgatcg catcatcata agtaatacga
     5581 gggaatggca attttgtata agtttttaag acttctttgt ctcgtcctag tacatctaat
     5641 gcatattcgc aatgatctaa aacattttgt actaagaatg ctacatattg ttcctgtact
     5701 tctaaacttt cttcttgatg agtgaaagcc atttctggtt cgatcatcca gaattcgatc
     5761 aaatgacgtc gtgtttttga tttttcagca cggaaagtcg gaccgaatga aaagactttt
     5821 ccgaaagcca tagcagcagc ttccatgtat aattggccac tttgagataa ataagctttt
     5881 tgatcaaagt aatttgtttc gaatagatcc gtagtgcctt ctggtgcaga accagtcaag
     5941 atcggcggat caattttgac aaaatgatgt tgattaaaga attcatacgt tgcacgaatg
     6001 atttcatttc tgatctgcat aatcgcatgt tgtcttgaag aacgcagcca taaatgacga
     6061 tgatccatca agaagtctgt tccgtgttct tttggtgtga tcggataatc gtggctctcg
     6121 cttaccactt ccacatttgt aattccgatt tcataaccaa attttgaacg actgtcttca
     6181 cggatttctc cagttactaa cacggatgtt tcttggtgta gatttttagc tgtttggaaa
     6241 acttcttccg acacttcgct ttttacaact acaccttgga aaaaggctgt tccgtctctt
     6301 aattgtaaaa atgcgatttt tccgcttgat cgcttatttg cgacccaagc gccgattgtt
     6361 actgtttctc ccacatggtt tttcgaatcg atgatttgaa tttgttccac gtatgactct
     6421 ccttttatat tccttgaatt tctttaggat taattttgac ttttactctc aataaattgc
     6481 ttgattctgc gtaccgcttc ttctaacgta gcgcgatcag tagcataact catgcggaca
     6541 ttttctggtg ccccaaagcc ttcgccagtc acaagcgcta cccctgtttc ttctaaaaga
     6601 tcttctaccc attgtgtgac attttcatat ttacacatgc gtagcgtttc ttttacatta
     6661 ggaaaaagat aaaaagctcc ttgtggcttt tcaagagaaa cacccggcag ttctgccaca
     6721 agcgaatata acgtattcag gcgttcttca aaggcgttcc gcatttcttc cactgtatct
     6781 tgctcgcctt tcaatgcttc aacagctgca tattgactga ctgctgtcgg attactggtt
     6841 gactgggaag caacagcgat cattccattg atgatcacag gatttcccac cgcataacca
     6901 atgcgccagc ctgtcatcgc atatgtttta gacacgccgt tgatgatgat agtctgattt
     6961 ttgattgctt ctgaaatcgt tgcaattgga gtaaactcat tgccattata aactaaacga
     7021 ccataaatat catcagcaac tatcaaaata tcatttttta ctgcccattc accgattgcc
     7081 tgcagttcat tcttgctata aatcattcca gtcggattcg atggagaatt gatgattacg
     7141 gcttttgttt tttctgaacg tgcttgttct agctgttcaa cagtaacttt ccagctattg
     7201 gattcttccc ctttcacaaa gacaggaagt ccttctgcca gttttacttg ctcaccgtaa
     7261 ctgacccagt aaggcacagg aatgatgact tcatcttgcg ggtcaaggat cgtttggaaa
     7321 agggtataca aagcaaattt cgctccgtct gttacgactg tttgtgaagg ttcatagaca
     7381 agtccatagt ttttcttcag ataatcaacg attgcctgtc gaagctctgg gattcctgct
     7441 gttggtgtat aatagctagc tttcccattg cggattgctt cgattgctgc ttcttggatg
     7501 ttttctggtg tcgcaaaatc cggttctccc acagtcaaac tcagcacatc tctgcctttt
     7561 gcttttaatg ccttggcctt tgccgcagct gccaaagtga cagacggttc taatcgtttt
     7621 gttctttttg ataactccat cccattcatt cctttacctt ttaaattccc ttgattgtct
     7681 tgacttcatc tccagattca aagccaatca ggtaataatt cagtttccca tttgtttctt
     7741 ttcctactac ttcccacaca ggctgatcat catacatccc taaagcagct ttttcgattt
     7801 ggatttcagg atgggccgca gcaattgtct gttttgcttc gttttcagtc agtccctttg
     7861 tttgatccaa tacttttact ttttcaccag atttaggaat gataacggcg atttcttttc
     7921 ctttatcatt tgtacctgtc agtgaaaagt atgtcttctt tcgagtaaac caataaaaat
     7981 gatcggtttc ctcaagattt gcatatttct ttgcgatttc tactgcttct ttcttcgcct
     8041 gcaccgccgg acgactggaa cgcaagtaaa aaatcgagct gatcacgatg accgctaata
     8101 aaaatacgat caagccaagt aacacgcgat taatcgtttt ttcctttgtc tgttttttct
     8161 tcaagggtcg tcgctccttt atcttcattc cttttcatta tagcagattt taattatgaa
     8221 aaaagacagc tcctctaact tccttcttca tttttcttta agaattcatg gatatcctga
     8281 tagatttcct ccatagctag ctctttgatc ggtacttttt tcggtaatgc atggatgatc
     8341 cgtgcgccat attttgcagt gactagtctt cgatccaaaa taagcaatac gccacgatct
     8401 gtctccgtcc ttatcaagcg acctaatgct tggcgtaact tcaaagctgc tttaggtacg
     8461 gattcctggt aaaaaggatt gatcccctct gattctaaat aagcgttcct agctttgacc
     8521 atcgggcgaa gcggattatc gaagggtaaa cgtgtgacta caacgatctg caaagcatct
     8581 ccaggcaaat ctacaccttc ccaaaagctg tcagcgccaa acaatacgct tttttctgac
     8641 aaaatgaagc gtttcaaaag cttctcccgg cttccaccaa acccttgagc tagtatttct
     8701 cgtccttttt ctagcataga cagatgcatt ttctgataga ccttctgcaa aacatcatga
     8761 gaagtgaata acacaagtat tggccgatct tcttgttcga tcagacctgt aagtgctgtc
     8821 tctaaataat cgatatatgc ttgattgctg acttgatgga cggcaggtgc ctcttttggc
     8881 acatagatcc ttgcctgttt ctcataatca taaggagagg caatcacttt aagaggtgct
     8941 gcttcaatgc caagcctctt agagagatag tgtcgattag ggccgatctt cagcgttcct
     9001 ccaatataaa gaatacgatc atatcgagga taccaaacag tcgacggcaa catagccgct
     9061 tgaaaatcat ggagatgaaa aatcatctgc tgcgctgtgt tcccaggaac gaaccaatgg
     9121 atcaaatgat ctcgccagtc ttccagccat tgatccatca gcaagtattg cttgtctaat
     9181 tgatcaaata ggctatataa acttgctaaa tcgatccgca tctggtttgt ccagctttct
     9241 tggataatct caaaagtcag acgcatttgt gactgtagct gctggatctc ctgataaaaa
     9301 agctgcaggt gatcaatggc tgtcccagat tccagtggca gctgatccaa catctctttt
     9361 gtcatcatga cttcttctgg atactgtccg ttaggttgct tgccgctcac taaactcatt
     9421 aatccttctg ccatacaaat ctgtgcttcg catagcgcag aaagttcttc tcgataaatc
     9481 gataaccagc gtaaggcttc atgttctttc ggtaaatagc tttgtattcg gtcaaacagc
     9541 tgatttggtt cttctaattg ctggatttgt ttatggaaat agttaatact taatcgtttg
     9601 tcatttactt tttcagcgat ttccggcaaa tgatgtactt catcgatcaa caaaaatgga
     9661 ctagctggaa gcaatggttc ttttcgctgt gtttcttgta ctaaaaacgc atgattgaca
     9721 atcaaaaaat tactttgcct gattttcttt tgcaagaaac gaacaaagtc ttgttcgtaa
     9781 aatgactgat ttcttgctaa aaatccaata cctctgtgcg cgatatctgc aaagaatgaa
     9841 tggttcaaat ttgttaaatg taattcatcc aaatcaccag tcttcgtttg cgtcagccaa
     9901 actaagaccg ccatttgata caaagcatat tgtttttgtt ctggcggttc cacaagtgtg
     9961 cctttaaaac gctgcaaatc aatatagtgg cgatagcttt tgataattac aggttgtatg
    10021 ggctgatcta gcaattgatt cagcaatgga atgtcttttt ctatgatctg ctgctgcaaa
    10081 actagcgaaa cggtactgat gacagcgggt ttttcaggtg tagccaaata actcaatggc
    10141 agcagataac cgattgtttt acccattcct gtagctgctt cgatcatcaa atcttttgat
    10201 tcatcttttg tgaaatggtc gtagaccgca ttcatcagtc tgttctgttc ttttcgatac
    10261 atcagtgttt taccaaacat tttttctttt gcttgttttt ttcttggata tgtccgctcg
    10321 ccataatgga cggatgtgaa tagttccact tcttttttct gcaaagctag cccatcgacg
    10381 atttctaatg agggatcaag tggctctggt ttttctttca tttcttcaat cacatgataa
    10441 atgaaacgac tcgtatccat acctgtgtgt ctacttaatc gcgcaatctg ctctaacgtg
    10501 atgattggca attttctcat ccgttcttcg atcagcaaaa gaagttgacc tgtcacttcg
    10561 gcatcactat ctgcctgatg aggattctca tgaataaatc caaggctttc tgacaaatca
    10621 gctaagcgaa agcttggttc cgtcggcaag aaaatttgtg caagttctac tgtatcgatg
    10681 cctggtatct tcaaactagg aagtccgcat cgcatgagtt catggttcaa aaaattataa
    10741 tcaaaataaa tattatgcgc gacaaatatg gtgtctgcca aaagattgta aatcgtttgg
    10801 gcgacatctt cgaaataagg cgctttttgg acgcgttgat tcgtgatccc tgttaaatgc
    10861 tggatttgtt ttgaaatctt ccgccctgga tgaatatcga tcgaaaaacg tgaagtgatc
    10921 cgacctgatt caatcatgac gcagccaaat tggatgatcc gatcttcttt tggattcgtc
    10981 ccagtcgttt cgatatcaac gactgcataa gttcttggtt tcaaaatatc ttcctcttct
    11041 cctgcctcta atgttctttt gaaattatac tacaaagtgc agaaaaatac tctcatcgct
    11101 ttttaaagaa aatagacaaa aacgcccaga cacgcaaatg tctgggcgtt tattttttag
    11161 tataggttaa ttaagcttta gtaacgtttg ttgcttgagg tccgcgttgg ccttcttcaa
    11221 catcgaaagt tactgcttgg ccttcttcta aagttttgaa tccgtcgcct tggatagctg
    11281 agaaatgaac gaatacatcg tttccgtttt ctgcagtgat gaatccaaat cctttttctg
    11341 agttaaacca ttttactgta cctgtttcca taataaaaat cctccttgtg tatcaacaca
    11401 tattttgcaa ttacttgaat ggtgtatatc tggaagatgt ttatttgaaa caagctacca
    11461 cagattaccg aacaaaaact actcctatag tatatcatac cgtttacaaa aaagctagag
    11521 tttttcgact ttttttatta aaaaaagttt tctcagcgat tacataaagt gaaaaaccga
    11581 actttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc tgatgttctt
    11641 ttttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca acggtcgagg
    11701 ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag cctatgacag
    11761 ttaccagaag aacaaggcaa accaatacga ccaacgagat tagtttttct tttttgctca
    11821 tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat gagtaaaagc
    11881 aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac aggtcggaca
    11941 gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag gaatcgcaga
    12001 atcaagatct ggtgtctgta cataaacatt tttgtacaga cgtgtgcctg taataggaaa
    12061 ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata gagacagcaa
    12121 acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt cccaattaaa
    12181 atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt ttttgtatca
    12241 taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt ttttaaacgg tgttccagaa
    12301 gtagcttctt cggaaataag ccgaaatttc acaaaaattt gagaaataat ttttgtcaat
    12361 ctcttcttat ttcttgaagc tgaccacttc tgtcacaacc tcttccttaa acggtgttca
    12421 aaagcttgca tctgcggtaa taagcccacc aaacaaaaaa tatgaagagc tatttttgct
    12481 tgctgttctt attacttgat gcagaacagc tttttcacaa cctctcatac acggtgttta
    12541 atcagctgac cttcggtatt agctcaaaaa acggcaaaat atgtgaaact atttttccgt
    12601 ttgtttctct aatactcagg tcaaaacact gatttcacaa cctcttttaa taacgaagaa
    12661 tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac acttttccgc
    12721 cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca tattctgttt
    12781 caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa tgtgacactt
    12841 ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc ttatctaaga
    12901 gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc ttcgcccctt
    12961 cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg tctgcacaat
    13021 aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaga gcaaataaat
    13081 aaatcggcca ttgttctgga ttttcgaaag aatccttcaa gtacgtatca actgcttggt
    13141 aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca tggaaagtta
    13201 ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca cctgtcagtt
    13261 cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat acttctttta
    13321 cttgtttgtt gctgacttca tacaatttca tggagtcgcg gttcaatccc aataaataat
    13381 aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga tcacttacat
    13441 agtattgatc gtctaccggg atactcaaac gatggatata ggtttggtca gcagttataa
    13501 tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac aaattttcaa
    13561 ttttttcttg gaacggggac cagtcatgtt cggaatattt tttctcaaaa cgtttctttg
    13621 cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga tgggcgacat
    13681 gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc aattgtgaca
    13741 ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca ttcctttgtt
    13801 tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc taaaaaaata
    13861 aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat aatttcctca
    13921 attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta agaaaaagaa
    13981 taaaagaggt ggatcttatg catttgatta tgattttcag tttattaagt attatcagtt
    14041 tatttgcttt cagcgcttcc cgcttattag atgcggaaac acagcctatt cctgtaaaag
    14101 tacgtaaaaa cgaccgctaa ccttccataa cgtgcgttct tatcctaaag ttttttcaga
    14161 aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa caaattaatt
    14221 acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt ggctagtctc
    14281 attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga tactttcaaa
    14341 gtaaatgcaa aagcagcctt tgctgtagat gcgcaaagcg gtaagattct ttatgatcaa
    14401 gatggagaaa aaaccatggg gatcgcttca atcacaaaaa ttatcggtct ttacatcgtc
    14461 cttgatcaag taaaagaagg gaaactatca tgggatgata aagtttcaat ttcagattat
    14521 gcagaaaatt tgagtgtcac cccagattta tcaaatgttc ctttgcataa agaaaacacc
    14581 tacaccgtta aagaattatt cgactctgca atcatccagt cagccaacgc ttcaatggtt
    14641 gccttggcag aaaaaatctc tggcagcgaa gcaaaattca ctgaacgaat gaaagaacaa
    14701 ttgaaagatt ggggtatcaa agatgcaacg atcgttaatg catcaggact gaataactct
    14761 tatcttggcg aaaaccgacc agaaggtact ggagaaaacg acgaaaatca aatgtctgct
    14821 caagatgtgg ctatcgttgc ccgtcatttg atcttggatt ttccagaaat actggatgta
    14881 tctagcacta cgacacaaat gtttggcgaa aacacgcaat caccagtaga aatggtcaac
    14941 tggaactgga tgctcccagg attcgtgaat tataaagaag gcgtggacgg attaaaaact
    15001 ggtacgactg aacttgcagg agcctgtttc gtcggtacga tcactaaaaa cgatcaacga
    15061 atcatcactg tcgtattgaa tgcagacggc catgcggaaa acccaagtgc ccgtttcaat
    15121 gaaacagctc gcttaatgga ttattgctac gacaattggt cagaaaaaga gcttggaaaa
    15181 gccaatgcaa gtatccctag tctaaaaacc attgatgtaa aagacggaaa agaatcaaca
    15241 gtgcccgttg tgcttaaaag tcctgtaaaa gtatgggtac ggaacgatat ggatactgga
    15301 aaattaacaa tcacaccaac tcttgacaaa aaacaagtca ctgacaatga gatccaagca
    15361 cctatggata aaggaacaaa aatcggtacc gcaacgatca ccttggcaga agataaatta
    15421 ggttatctag aagacaacaa cgcgccatcc acagaaatca tcacggataa aaccgtagaa
    15481 aaagcaaata ttttcgttat tggctggcga cgcgtcgcag aatttttcgg taacttgttt
    15541 taattgaaca aaaagaaaaa agcatctttc catgtggaag atgttttttt gctttttcta
    15601 gtttaaataa cagctttttt catctatttt cgttatactg tataagaaaa aggagttgaa
    15661 tttatgaatc taaccagaga tctgattttt ttggttctct atcttattgg ggtattctcc
    15721 atcgtttatt ggcgaaaaca gaaaaaggat ccttccttgt tcttttacag cagtacgtgg
    15781 acatttgcgg taatcttgac ttattttgtc gtgttggaaa ttttttattc gaccttttat
    15841 tttttgattc ccttagtgtt tttcagtatc tttgcctttt cctatttttc agaaaagcga
    15901 aggctgctga atggtctttt attcaatgtt ttcctcatta gttttggtat ctacttgttt
    15961 gtcttgctat acgaaacaca aaatattttt cttggcggac tgattgcctt gatcacgatc
    16021 ccgttactgc ttgtctttct attcggcatt tatggattga tcgtttttct tttttggaac
    16081 ggtgtcacag ttttacgtag agagtcgcat tcattagcta atcttttaac gttgatacta
    16141 gccatttttc ttacattgtt tcttgttttt gactttttct tgttaaaata tttaccacaa
    16201 tggataaatg ctttgttttt ctgcatccca ttgatcttga tctatctatt tatcgtattc
    16261 tacaactttt tgactgtctc attcttgtat cagttcaacc gccctcgata caaccaagac
    16321 ttcatcgttg tgttaggcgc cgggttgatc aatggagaaa cagtttctcc tcttcttgcc
    16381 aagcgaatca ataaggcgat tgctttttat tgggcacaaa gccgtgcgac attaaatccg
    16441 cctatcctat taatgtcggg tggacaggga gcagacgaaa aagtaccaga agcaatggcg
    16501 atgaaacaat atgccatgga acaaggaatt cctgaaagag atattcttgt cgaaaccaat
    16561 tcgacaacca ctttggagaa tatgcgctat tcaaaggaaa tcatggatca gcaaatgaaa
    16621 gggccctatc gcgcgatctt cagttccaac aattaccaca ttttcagagc tggtctctat
    16681 gcacgacaag cgaaactgaa ggcaaatggc attggggcaa aaacagcttt ctattacttg
    16741 cctaacgcgt ttttaagaga atacatcgcc atcttgatga tgaacaaaaa aagacatatg
    16801 atcatttgcg gattgctttt cgcaggttcc gcattcttat cactgatcac tttacttttc
    16861 taaaaaacca aggtgtgaca aaacatatgt cacaccttgt ttttttcttt tattctcttg
    16921 acgattggca agaatagtat tccttttttg acggctactt gctgtgcaga ataaataccg
    16981 ctgtttcctg aacacataaa gctgatcaag cagatcataa agaagtaaac agcagcttgt
    17041 gaaccaaata attcgattcc catcacaaaa caggcaatcg gtgtatttgt cgcaccagaa
    17101 aataccccga taaaacctaa tccagcaaga aaaggaacag aaacatggag caaaggcgct
    17161 agtactgcgc caagcgttgc accaatctca aatagtggtg tcacttctcc cccttggtac
    17221 cccgcaccta aagacaagac cgtgaagaat aatttcccaa taaaatcata agcatgtgcc
    17281 tgtccattaa atgattcctg cagtatcgga agactcaacc caaggtaacg ttgtgtttgc
    17341 aaaatcaacg ctgcggctac aactactgct ccacctatcg tatttcgcca aacaggatga
    17401 ggaatccatt gcgcataccg cgcttttaaa aagacgatcg aacggctgaa tacccaacca
    17461 atcaaaccaa aagcaatccc agcaacaaaa actttgaaga acagcaacat actccattca
    17521 ggaatcacac ccatttggta atgtagatga gaaacaccat agctttctgt catgaaattt
    17581 gcaaaaagcg cagcaaagaa gctaggaaag attgcttctg ttcggacttt accgattgcc
    17641 aacacttcta atccaaataa tgttccagct aaaggtgtgc caaatacaga actaaaaccc
    17701 gcactgattc cactgataac caaaatctcc cgttctgctt tatccaatcg gaataaatgc
    17761 gctatattat cagctaatgc tccccccatt tgaactgctg ttccttcacg accaacagat
    17821 cccccaaata aatgggtagt gatggtccca aacaaggtca atggaatgag ccgcaaaggg
    17881 atcttctctt ctcctccatt cccttgatcg atcactaagt tattcccacg actagaaaga
    17941 ccgccatgat acgcataaag ataagcaaaa agcgcgccgc tgactggcaa tagataaaat
    18001 agccaaggat gtgctagtcg gatatctgtc acgaacgtca ggctatttaa gaaaaaagca
    18061 gacaagctcc ccatgaatac tccgagaatc gctgtgacca ccagccactt caacatgtac
    18121 atcaaaatac gcactggact cggtaattgt ttttccataa aaaattcctc ctcaaataaa
    18181 aaaacgccta ctaaagaaag gggctggccc cagactttag taggcgtcat tagctatctt
    18241 acgttagcat ttaaaggcga acaccatcac ctattcactt ccattaaaag atagcatatt
    18301 tttctgtaaa aaacaataaa attatcgttc tttctttaca cgttcagcaa attcatagaa
    18361 aggagccaat ttcgttaact gttgattaca ttgatcacta tcatgacaaa tataattccc
    18421 ctttttcgta tacgtgccat cagaaccggc tttcgttgta gaaagaaaga gcgagacatt
    18481 cgatgttttc tgacagatcg cacagattcc cttattaatc gttggtgata aagtaccgct
    18541 gatccctttt aattttccat cttcgtaata aaccatgaat tttttttgcg tccctggatc
    18601 attccaaccg atgtacgtat gtgcttgcaa gtcgatttca ttccaagcgg gttgtttgag
    18661 ttttttcact tttcggaata atttctcgat ttgtggtttg ctcggctgca taaacggctg
    18721 gacgatttgc ttcagctcct ccaatgctcg ttctgcttgc gtttttgtca gttttacatc
    18781 taaaactgtc gttaaaaacg tatcgatttc tgatggttcg taacctaata catcgcgaat
    18841 cttttcagct gctagagcct gaaccgtttg taccgttttt gagtcattga cagatgagta
    18901 cgcatttaat aactgctcta cttctctttt tataaaaaaa tattgatatg gtttcattgt
    18961 ttgttccatg attttaaagt cctttcttct aaccaaagtg catactttgt agaaaaaagt
    19021 gatcttctgc aaagtatgtg ttacctgaag atcccggact cttttaaata agatacgttt
    19081 tgcatcttat catcaccccc tttaatgttc attcttctat gtacatgatt cattcgataa
    19141 ataaaagtaa accgtatctt gagcagatag tcaactgcaa acagaaaaag gactgtgaca
    19201 aaagtcgtgt caaagtccct ttctacaaac aaacggtgtt ccagaagtag cttcttcaaa
    19261 aaataagccg gaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    19321 ttgaagctga cccacttctg tcacaacctc aatatggtct attattggtt ttacctgtta
    19381 aatcgaggat tcttttccga agtaacgttg ccatctctta cgcatacttg ctgacatagg
    19441 ctgagcggct tctttgactg cgcagtattt gtctacgaat gttacgatat atccttcttt
    19501 gtacttaggc ggtgcaatcg ttgcgcccca catgtgcttc aaaatgatat ctcgctcaag
    19561 atccgacaaa tcggtgatct tttctgcatt ctttacagcg attcttggat ggatatacgc
    19621 atgtgtgcct tcatcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag
    19681 tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata
    19741 gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaattcgc
    19801 taattttttc actgcttctg tttctaaaag atcttctaca taagacatat attcttcgtc
    19861 ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc
    19921 tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgcctt ggataaaata
    19981 gccaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacaat ccctgccgca
    20041 accccaacat tcaacgattc cgcatttcct ttcatcggga tatatacgtt ctgatcagtc
    20101 aaagacaaga tttcctgact taccccctga ccttcgttcc ccatgattat tgcgaagtta
    20161 tctgattttt ctactttgtc taatgcgtgt gcttcttcat ttaattctgt gccatacact
    20221 gtaaaccctt tgtctttcat taaaggaatc acttctgtca aatctttttg caacacaggc
    20281 aaatgataat tgcttccctg catgctgcgc agcacctttg tactataaat atctgccgtt
    20341 cctttgccta ataaaacacc agccatatca aatgcatctg ccgtacggat catcgtccct
    20401 acatttccag gatcttgtac attatctaat aacagccatc ctcctgaaaa atctggcgtg
    20461 ccttcagccg ttaacgccat cactgctaag attccttgtg gtgtaggtag atccgataca
    20521 gcatccatga cctcatccga aactagaaaa gtagaaatct ctttgtttgc ggccagccag
    20581 tctccccatt ctttcatgcc tcgctgtgtc acaaaaagtt cttttatttc tgcatcagac
    20641 gacgcagctt cttcgatcag atggaaccct tccaaaagat attcttcctt ttcttcccga
    20701 tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc
    20761 tctttcacat tcctcacctc cccatgatta tatcatggaa taggtgcttg agcttgtttc
    20821 atcctaaaaa aatcggtatc attaatttat aaaataggaa agaaaggtga cgaacatgcg
    20881 caaagttaaa atgaacgtcc aaggacgcgt ccaaggcgta ggatttcgct acatgaccaa
    20941 gatggtcgct gatcaactag gcgtgactgg aacggtaaaa aacgaagacg acggctcagt
    21001 cacaatcgaa gcaatcggca atgacgacat catccagaaa tttattgaag aagtcaagaa
    21061 atcaccgagc ccaagtggac gagtgcagta tgtggatgtc caagaagacc cgatgattga
    21121 ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaagctggtc tgcatcaagc
    21181 attaaggaca ggttgtgaaa aatagctctc catatttttc aacaggctgg acttaatgcc
    21241 gtagatgcaa gcttttgaac accgtcaata aggttgtgag aaagtcgctt agttttgagt
    21301 agtaaggaga attttgtgaa aatggctttc tacatttttt cataaaattt gacttaatac
    21361 cgagaaactg acttttgaac accgtcgata aggttgtttt tgaggcgctt tgcctcgagt
    21421 attaaggaga aacattttca aaatagcttc tcatattttg ttaataccga gaaactgact
    21481 tttgaacacc gtcgataagg ttattcttga ggcgctttgc ctcaaaaatt aaggacagca
    21541 gtgaaaaagc tgatctatca cttgcagtga gttcatttga ctccgctttt tcgggcagaa
    21601 aaaaagtttt tagtttatta aagtaagaaa gaaacacttg gaatcattct actttttcct
    21661 agtatttctt tcttgatttt ttgtcttttt ttcaaaattt ttcgctacgt aaaagaacga
    21721 atatttatat gaaatttcta tgaagttgat tgaattccat gcgctttttt agtatagtta
    21781 agtttgtgta aaaattatag aagaggaagt attctatgaa taaatggaaa aactggttat
    21841 tgggatccgg acttgtcagt atcctgctct ttttatctgg ctgtgtgcgg atggattcaa
    21901 acggaaaccc tgacacttcg ggaatcgttt atcgagtact cgtccatcct atgggccaag
    21961 cgattacata tctagttgaa aatttcaatt ggtcttatgg ctgggcagtt attgcaatga
    22021 ctgtgatcgt ccgtatcatc atcttgccac taggtattag tcaatcgaaa aaaacaatga
    22081 tccaatctga aaaaatgcaa gcgttaaaac cacaagttga agcagcccaa caaaaattga
    22141 aagctgcaac aacacgtgaa gaacaaatgg cagcacaagc agaaatgcag caagtatacc
    22201 gcgaaaacgg attgagtatg accggcggaa tcggctgtct gcctctattg atccaaatgc
    22261 cgatcttctc tgccttgtac tttacggcac gttatacaga aggtattcgg gaatcatctt
    22321 tctacggcat cgatttaggc tcaccaagta tggtacttgt tgtcattgca ggggtcgctt
    22381 atctgcttca aggatacatc tcaacgatcg gtattcctga agaacagaaa aagacgatgc
    22441 gtacgatgct gatcgtctct cctgctatga tcgtcttcat gtcgatcagt gcgccagccg
    22501 gtgttacact ttactgggta gtcggtggtg tgttcagctg tctgcaaaca ttcatcacaa
    22561 acgttatgat gaaaccacgt ttgaaagcac aagtggcaga agagttgaaa caaaacccac
    22621 caaaacaagt cgtcactcca agaaaagatg tgacagaatc agctaaacca gctgacagca
    22681 aacaagcaac caaacaaatc aaacaaccaa aaaacagtac aaacaacaaa ggccgcaacg
    22741 caggaaagca gcagaagcgg aaataaaaat atatgacaaa aaactgtaga caaataaaaa
    22801 aatttctttg ttctacagtt tttttgttac aatcaaagaa aacgttcgct tttcgaggag
    22861 ggatgtataa tgatgttcaa acaatcaatg gatagtcgaa tggaagaaga caaaatttcg
    22921 ctagatgcac ttgttcctaa aaatcattta gtccgtaaaa ttgacaagtt attgtcattt
    22981 gattttattt atctcattgt tgaatcaact tattcgacca tcggtcgacc tagcgttgat
    23041 cctgtcgtct tagtaaaatt agtattcatt caatatttat ttgggattcg ttcgatgcgt
    23101 cagaccatta aataagttta aacaaaccta gcttatcgtt ggtttcttgg gcttagttta
    23161 attgataaag ttcctcattt ttcaactttt ggtaaaaact atgcacggcg tttcagagaa
    23221 accgatttgt ttgaacagat atttatcatt attctggaac aagcagttgt tgctagattt
    23281 attcatgaag aaattttgta tatggattca actcatatta aagagaatgc gaaaaaacgt
    23341 atttttacaa aagatatggc acataaagaa gccattttat accaaaaacg attggaagaa
    23401 gaaatcaatg aggcaagaat tgccgaaggc aaacgccatt ttggttcaat cattcgtcag
    23461 gaggtggtcg aaaggaaatt tagcgtcgca gatccagaaa ttggttatta tgtaaaaaca
    23521 gaacgagaaa aacagtttgc ttattcttct catactgttt gtgatgaaaa tggttttgta
    23581 ttagatgtca tgattacgcc tagaaatcta cattacagcc gaatgctcgt gccacaaatc
    23641 gaacgtgtta aatcacgtta tggtgtagct gctgatgctg cgtacaaaac accttggaac
    23701 gccaagtatt taatcgaccg aaaactacga cccacttttc cttatactcg acccaaagga
    23761 aacaaagaac gttttaaaaa gaaagatttt gattatgatc cctattataa ctggtaccta
    23821 tgcccgaatg atcaaacact tcagtttcgc acaactactc gagatggcta taaaaaatat
    23881 gtatctaaat cttttatttg tgaaagttgt ccattattga aaaattatac agaaagccag
    23941 aaacaccaaa aagaaataca tcgacatatt tgtgaagatt acttagatga agcagaacat
    24001 ttacgccata cggtgtacaa tcgcgaaaaa tataaaaaaa gaaacgattg aacgcatttt
    24061 tgcagacgca aaggaaaagc atggagtgcg ctacaccaag tatcgaggct tggaaaaaat
    24121 caggtgcata cgatgcttgt ttttgtcgca atgaatctga aaaaattagc cacttggcag
    24181 tgggagcata tgtctttata tcttttatta tacaaaaata gacaaaagta tcagtctaca
    24241 ctcttagtca agaggaaact gatgctttta tctacagtct gagagagtgg gacaatagtc
    24301 ctttctccaa aagaaaacaa gtccgacttt gatagttaat tttaaaatcg gacttgtttt
    24361 ttcttcttta cgtcttttcc tctccatgta tttccctaat tttcttaaat ttaacgccat
    24421 gagtgccaag ccaatgttaa tcttggctcc ttgtttccct cgtaagtgga aatccgtttc
    24481 cgatagatcg aaccttcttt ttcctctaaa aacttttttt acattctgct ttgaaataac
    24541 gccatgtatt attcactaaa atttgtcggt ttcgctcact ttttgctttc gtacattgac
    24601 tacgaacagg gcagcaccac cataagccgc ctgccagtta cctctcactc ttaccgggtc
    24661 tttcagaaca cccggatgct ctaacacatc actcggctag gctccgttat tgaagaagaa
    24721 agccccatat ctttccatgg catcctcggc cagcttaaga agctcctcca tctgttcgga
    24781 gaccttcctc acatatatgg gcaaaggcca tgaagacctc caccagactg ttcatgacct
    24841 tcttcagtgc tgcgatcatc tgctctctct tctccatggc ttacacctac tcgacagaat
    24901 cagcggcatc agaggcaaga gcatccttca tgtgctgtgc caggaagtca tccagctggt
    24961 tcatagaaaa atcgacaccc ttgttcatgg cctcgctgat ttccatcagc ttctggttca
    25021 cctcttcctc agacaggccg gtgcgctcac agatggaatg gagcagatga tcgtgcatct
    25081 ctgccatctt ctggtccatg tcgaattttt cgtggcagca atctctgcgc catgccttcg
    25141 gaaatacggc ttccccccct catcagactg tgtgtttggt tccagctctt tcttccggga
    25201 ttcttcgctc tcggaaatcg gtctgtacag tgaacacaca taaatattct tcctatgact
    25261 ggtatcactc atggcttgtc tcctttattt gttttgtcga gtcctacctc aaaggaggtc
    25321 tggccagcat ataggtgttc atctgactgt ccctttcaaa attagtgtcc tcatctatga
    25381 tttcgggcgt tttataactc ctccggacaa aatttttgaa aaaatttgtc gagggcttaa
    25441 tacacctctt tcataactgc aaacgcacgc ttcaaggtct tggtgatttc tgcatgcgac
    25501 atgcgcagat ccctcgcaat ctgctgctgg ttcttgttca ggaagtaata atgctcgatg
    25561 acctttctct gattaaaggt tagcttctgg atctcttctt gcagacgctt acgctccatc
    25621 ttcttaaaat cagtcggagc aatcttctcc acaatgtcag gagtatagga catcatgcag
    25681 tcctgtgtgt agctgtcctc gatggtctgc tctatgcctc cgaggtatct tgcatagttg
    25741 gattccagac ggttctctgc atcatggtca tgtagatggt ccactgatag tccatatact
    25801 cctcaaccag gatgaagcta ttcttatcgg cgaaccgata caacattcca ttcatgcggt
    25861 cagctgtgaa gatggagtac atatcattgc gaatatagag gataaagtcg ttgcgataca
    25921 cggtcaacag agaatcgtcc atctagaact gagccacact cacttggcac catattatca
    25981 ctcagctaac ggaagccggg ctgctttacg cctttggtgc tgtccttgat ttccttccat
    26041 atactgcttg ccgagattga tgattcttct gacatcgatc aaagtaacag gtaatttaga
    26101 atcttccaca aacctgatta tctcctctac tactttcggc tcaatatctt ctaatgcgat
    26161 cacgatttta tatacctgct acttcacaat aacatcctga acatcagata ttcgtccaaa
    26221 atactttaat ttcgccaatc catccccata attagcaaat cctggttctt caagtagaat
    26281 atcctctttc tttcgatctt tcacatatcc aataatattt gcatctgcgt ctggatctga
    26341 taacatggcc aaaccatatt ctttagccag gtttccattt tccacaacca aaactcgagt
    26401 atgggacttg ctgcctatct ttttcagtaa aaactgaaat acagcattct tgacgagcaa
    26461 caaaacgcac gatatgatcc aaaataaaag caatggccat ttggaaaagt atttcacatt
    26521 agcgatatat aagtataaga aagcaaggaa gaacaaactt ccaataccgg ttaacgatac
    26581 tattttaaaa atccgttttg atactttctg aaataggtct tattcgttgc acgaaaaatc
    26641 ctcaaaaaat ctgcaatcaa aatactatat agcgcagcca tcatcaaata cggaactgac
    26701 aacatattga tcccgggagc agcttctaaa acgtggtaac aaataaacat ggccaataga
    26761 taggctacaa aaatagatgc tgcatctcca atacagtcaa aaactgtgtt ccaaaatcgt
    26821 tccttgataa tttcattgat tctcccctta taataatatc gaatgctcca acatcggtca
    26881 gaatcatctc ttctgtctat cattcgccac gtagaagttg ttggaaaaga gtgacaaccg
    26941 ttcaagacga acggctatat tgtattaatt attctgtgta tcaactaacc actcaacaaa
    27001 ttcacgcact gcaccattac caccatcatg ttcagcgata aaatctgaaa tttctagaac
    27061 ctttttaact gcatcgtgcg gacaggccac aataccacct gcacttttaa caggatgcat
    27121 acaagataaa tcgtttatat cgtctccaat atatgcaaca gtacttagat cactagtaat
    27181 ctcaagcagt ttctctattt tattgtctat tccctgataa agaatgttga taccaagttc
    27241 cttacatcta ttttctaata ttttggaacg acgaccagtg ataataatag gctcaatatt
    27301 atgggctctt acaatatcgt gaatagcgca accatcttta atattgaacg ccttcataat
    27361 ttccccacac tcacccatat atatctttcc gtctgttaga gtaccatcaa catccataac
    27421 cagaaattta atttggctca tacactttcc ccccctttca ataattgata gaaatcttaa
    27481 atacagcttt ctttacttta gctgattcat tcactcttat gcaaggcata tgagcatcct
    27541 caggagttag tagcagcagc ttccctcctt ctaagagtac acaattgcca actattgaat
    27601 tactgtaaaa cacaatatcc ttgtcagctg aataatctac ttcaatctgt aaattagata
    27661 tagattctac tacaatatac tcgcatccta agagaataca ttgaatgtct aaatatttca
    27721 agtgagattc gtacattct
//
LOCUS       DADVXB010000023        27664 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.023, whole genome shotgun sequence.
ACCESSION   DADVXB010000023 DADVXB010000000
VERSION     DADVXB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.023"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            90..1349
                     /gene="lysA"
                     /locus_tag="KB902_000769"
     CDS             90..1349
                     /gene="lysA"
                     /locus_tag="KB902_000769"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBB6807614.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1336..2136
                     /gene="dapF"
                     /locus_tag="KB902_000770"
     CDS             1336..2136
                     /gene="dapF"
                     /locus_tag="KB902_000770"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBB6807615.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2139..3020
                     /locus_tag="KB902_000771"
     CDS             2139..3020
                     /locus_tag="KB902_000771"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBB6807616.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3017..3733
                     /locus_tag="KB902_000772"
     CDS             3017..3733
                     /locus_tag="KB902_000772"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBB6807617.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3739..4434
                     /gene="dapD"
                     /locus_tag="KB902_000773"
     CDS             3739..4434
                     /gene="dapD"
                     /locus_tag="KB902_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBB6807618.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4450..5451
                     /locus_tag="KB902_000774"
     CDS             4450..5451
                     /locus_tag="KB902_000774"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBB6807619.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5448..6809
                     /locus_tag="KB902_000775"
     CDS             5448..6809
                     /locus_tag="KB902_000775"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBB6807620.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6769..7920
                     /locus_tag="KB902_000776"
     CDS             6769..7920
                     /locus_tag="KB902_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBB6807621.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7895..9064
                     /locus_tag="KB902_000777"
     CDS             7895..9064
                     /locus_tag="KB902_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6807622.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9239..10618
                     /locus_tag="KB902_000778"
     CDS             9239..10618
                     /locus_tag="KB902_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6807623.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10899..11696
                     /locus_tag="KB902_000779"
                     /pseudo
     CDS             10899..11696
                     /locus_tag="KB902_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11885..12553
                     /locus_tag="KB902_000780"
     CDS             11885..12553
                     /locus_tag="KB902_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBB6807624.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(12753..12983)
                     /locus_tag="KB902_000781"
     CDS             complement(12753..12983)
                     /locus_tag="KB902_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807625.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(13110..14492)
                     /locus_tag="KB902_000782"
     CDS             complement(13110..14492)
                     /locus_tag="KB902_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6807626.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(14648..15835)
                     /locus_tag="KB902_000783"
     CDS             complement(14648..15835)
                     /locus_tag="KB902_000783"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBB6807627.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(15842..16873)
                     /locus_tag="KB902_000784"
     CDS             complement(15842..16873)
                     /locus_tag="KB902_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6807628.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(16889..18343)
                     /locus_tag="KB902_000785"
     CDS             complement(16889..18343)
                     /locus_tag="KB902_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6807629.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            18518..19423
                     /locus_tag="KB902_000786"
     CDS             18518..19423
                     /locus_tag="KB902_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6807630.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            19514..20191
                     /locus_tag="KB902_000787"
     CDS             19514..20191
                     /locus_tag="KB902_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6807631.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            20188..20358
                     /locus_tag="KB902_000788"
     CDS             20188..20358
                     /locus_tag="KB902_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807632.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            20472..21368
                     /locus_tag="KB902_000789"
     CDS             20472..21368
                     /locus_tag="KB902_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6807633.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21423..22793)
                     /locus_tag="KB902_000790"
     CDS             complement(21423..22793)
                     /locus_tag="KB902_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6807634.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            23031..23777
                     /locus_tag="KB902_000791"
     CDS             23031..23777
                     /locus_tag="KB902_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6807635.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            23774..24613
                     /locus_tag="KB902_000792"
     CDS             23774..24613
                     /locus_tag="KB902_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6807636.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            24614..25564
                     /locus_tag="KB902_000793"
     CDS             24614..25564
                     /locus_tag="KB902_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6807637.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            25705..26457
                     /locus_tag="KB902_000794"
     CDS             25705..26457
                     /locus_tag="KB902_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807638.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            26476..27627
                     /gene="queG"
                     /locus_tag="KB902_000795"
     CDS             26476..27627
                     /gene="queG"
                     /locus_tag="KB902_000795"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBB6807639.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPDIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         9080 a         5037 c         5821 g         7726 t
ORIGIN      
        1 tttgtttaat attattccaa taaaattcaa atctttatca aatgaaattc caataaaaac
       61 ggaaaaaaag tgaaaagagg aatgaaaaaa tgacagaatt gataattggc ggagtcacag
      121 caagcacatt ggcagaaaag tataagacac ctctgtatgt gtatgatgaa gaaaagatga
      181 gacaaacgat gctgtcattc aagcgaggct ttgtatcgaa acgttttgat acaaaagtgc
      241 tttacgcctc taaagcattc caaacgattg agatgctgca tttagttcgt gaatatggat
      301 tcgggctaga tgttgtcagt ggtggggaaa tctataccgc tttgcaagct gattttccta
      361 gagatactat ctacttccat ggtaacaaca agacgccaga ggaactgatc tatgcacttg
      421 aaaatgattt gttgcatatt gttgccgata atttgatgga agttgaatta ttagcagaat
      481 taagccaacg ctatttaaaa aaaatctgta tcatgcttcg gttgaatgtc ggagtagaag
      541 cacatactca tgaatatatc gtcactgcgc atattgattc aaaattcggc atgagctatg
      601 aaagtaaaga gtgccaacaa gcccttcagt tgataaaaga aagcagctat ctagagttag
      661 aaggatttca tgctcatatc gggtcacaaa tttttgatgt tactgcttgg ttagctgaaa
      721 tcgacaaatt gacgaattac ttaaccgatt ttgaccaacc tctttccttg aatcttggcg
      781 gagggtttgg gattcgttat acacaaaatg atcagccgat cccagtcgaa gaggcactaa
      841 aaaaactgat tgaatatacg gaagaagctt tggaaaaacg aaaactgacc attcgtcaat
      901 tactgatcga accgggtaga agtattgttg gagaagctgg tacaacacta tacacgattg
      961 gtttcatcaa aaagacacca cataaaaaat attactttgt agatggcggg atgacagata
     1021 atatccgtcc agctctgtat caggcagaat acgattgtga tttagcagca aaactgtcgg
     1081 aagaaaaaac agagaaagtg acgattgcag gaaaaatgtg tgaatcaggc gatgtggtaa
     1141 ttaaagaagc ttatttgccg aaagcagaat cgggtgatct tttagctgtt tattccacgg
     1201 gagcttatgg atactcgatg agcagcaact acaatcgagc gacacgacca gcagttgttt
     1261 ttgtcaataa tggccaatca agactgattg ttcgcagaca agcattttct gatctactaa
     1321 ggggggaagt ttcctatgat ccttcataaa tataatggct gcggaaatga ttttatctta
     1381 ttagattacg cagaagacac agattatagt caattagccg cttctttatg cacaaaagaa
     1441 aaatatgata tagacggatt gatcgccgta aaaatcgatc cgttggaaat gatctattac
     1501 aacaaagatg gcagccgcgc gccgatgtgc ggaaatggca ttcgctgttt tgctcgatac
     1561 gtaaatgatc agaacatgat gaatgaacag gaattcaacg tagagacatt agcaggcaca
     1621 agaaaaatta cggtgttgga tccctcacct ttttattgca gcgtagatat gggagtgcca
     1681 gatgattctc cggaaaaaat caaagctaat caaacttatc caataaaaaa ccaggaaata
     1741 gagatcaatg gtgaaaaagt aacgatcact agtttatttt taggaacgat tcataccgtt
     1801 gtttttgttg aaaatgcgcg tgaggaagtc tggagaaaaa gaggtgaact gatctgtcat
     1861 catcctttgt tcaaagaaaa aaccaatgtc aactttgtag aagtagtcaa tgaacaagaa
     1921 ttgatcgtcc gtacctatga aagaggagta ggttggacac ttgcttgcgg tacaggttgc
     1981 tgtgcctctt atgtggttgc taaggaaact gggaaaattt cagcagatca ggtagttgtt
     2041 cacttggaac aaggagactt gatgatctct ggtgaggatg cgatacaaat ggctggccca
     2101 gcagttcatg aatggacaag aatattggag gaatgaagat gataaaaggt tcgatcgtgg
     2161 cgctgatcac gccgatgaat gaagagggat cagtagatta tgctggtttg gaaaaattga
     2221 tccaattcca tttagatgaa caaacagatg gattattagt tttaggtaca acaggagaat
     2281 cttctacgct cacacaatct gaggaggagc agatccttca actgacagta aagaaagtgg
     2341 ctggccgtgt gccggtgatt gcaggagctg gaacgaataa tacgaaagaa acgattgaaa
     2401 aagcgaagca ttttgcttct ttgggggcag acgcactttt ggtcatcacc ccttactaca
     2461 acaaaacaag tgatgcagga ctagctgctc attttacagc aattgcagaa gcctcaccga
     2521 ttccgcttat tttgtataat gttccttcta gaacaggcat gtcgattcca atccatgtat
     2581 tagtaaattt agcagaacat cctaatatca ttggtttgaa agaagcctca ggagatatgg
     2641 cttatgtgat ggatgccgct cggttgattg gagaagaatt cttcctttac agtggaaatg
     2701 atgatttgat cctaccagta atgagtgtag gaggaagcgg tgtaataagt gtatgggcga
     2761 atatccaacc taaaatagtc catgaattag taaaagatac gcaggacgga agatggcagc
     2821 aagcaaaaga aaagcaatta aatgcacttg aactgatcca tgccttgttc agtgagacca
     2881 atcctattcc tgtcaaagca gccatgtcat tattagactt accttccgga cctctacgcc
     2941 tgcctttagt ttctctttca aaagagaaaa agaaacaatt agctcagctt ttgttaaaag
     3001 aaaggacggt tgaaaaatga aaatcggact gattggcagt ggacagatgg gaaatagagt
     3061 cgaagaagtt gcacaagaaa gaggagatac ggtccttctt ttacggacgg cacctaaaga
     3121 agcaactacg cttgctttta cggaactgcc agaactgctt attgattttt ctcatccaga
     3181 taatttagag aaaatccttt cgtatagctt atcatatcaa cttccgttag tcattggcac
     3241 gacaggttat acacaatcac agttccaaga aataaaagaa catgccaaac atgtacctgt
     3301 gatgtatagt gctaattttt cgttcggcat catggtgatg aatcaactaa tcaagcaagc
     3361 agctgcaatg ttgcaaggct ggcagatcga actgattgaa aaacatcata gtcgtaaaaa
     3421 agatgcacca tctggtactg caaatatgct gcttcaaaca atccaagaag tgcaaaagct
     3481 gcagcccgta tacaactggc aagggaaaaa aagagaagaa aaccaaattg gtgtacacag
     3541 tattcgtgca ggttctttac ctggtgaaca tgatgtattg tttgctgcta ctgatgaaat
     3601 atttacgatc aaacatgaat ctttttctaa tcgaatcttt gctgcaggcg cagtagaagc
     3661 agcggactgg ttgaaagatc agtcaccagg ttattacaaa ttagaagatt tattaatgga
     3721 caaaggggtg taaaaaacgt ggaagctcaa gaaatcatcc gctacattca aacggcatct
     3781 aaaaagacgc ctgtgaaagt ctatctgaat gtaaccgagc caatcgaatt taaagaaagt
     3841 aaagtttttg gtgaaggaag cagcttcgtt gtttttggtg actatgagac gattgctccg
     3901 gttttagaag ctgaatcaga aaaaatcatt gaaatcgaaa tcgaaactgc tgcaagatac
     3961 agcgcagttc ctttgctaga tattaaaaaa attaatgctc gtatcgaacc aggtgctatt
     4021 atcagagatc aagtgtcaat cggcaacaat gccgtgatca tgatgggagc gattatcaat
     4081 attggtgcag taatcggtga aaacacgatg attgatatgg gtgctgtctt aggtggacga
     4141 gcgacagtgg gcaaaaactg ccatattggt gcaggagctg tcttagcagg tgtgatcgaa
     4201 ccagcatcgg ccaaaccggt tatcgtagaa gacggcgtac tggtaggtgc gaatgcagtg
     4261 attgttgaag gtgtccatat cggaaaagat gcagtcgtgg cagcaggagc agtggtttta
     4321 gaagatgtgg cagcagaaac tgttgtcggt ggaatacctg cacgtgtatt aaaaataagt
     4381 gatgatcaga caaaagaaaa tacagcattg attgctgcgt tacgcgaatt atagaggaga
     4441 tggagaaaaa tgcgcgaaat agatacctgt attgtggggg caaccggatt agtcggccaa
     4501 acgatgctca aagtgttaga agaatatgat tttccagtag gacgattgaa attattagct
     4561 tcaaaacgtt cagccggtaa agtttgtgta ttcaagaaaa agaaacacac tgtacaggaa
     4621 ttgacagaaa cttcatttga aggatatgat ttagcgctat tttctgcagg tgcttctgta
     4681 tccaaagagt ttgcgccaat cgcacgaagt cagggactat ttgtcataga taattcctca
     4741 gcatggcggg aagattcgga tattccatta atcgttccag aggtcaatct ggaagactat
     4801 acattgaatc ggctgattgc aaatccaaat tgttcaacca ttcaagcggt acttccgctt
     4861 aaagctttac aagaagcctt tggtatccag cgagtcaatt attcgaccta tcaagcagtt
     4921 tctggttccg ggcaaaaagg cattgaagat cttcatcgta cgcaaaatga cgaggaacca
     4981 gttttgtatc cttataatat tagccaaacg gtgattccgg aaatcgatca gcctttggaa
     5041 aatgggtata caaaagaaga acagaaaatg ataaatgaga cccgtaagat tctgcatcag
     5101 cctgctttgc cagtatcagc aacctgcgta cgtgtgccaa tcgaaaatgg acatggagtc
     5161 tctgtggcag ttcaactgca aaaagagttt acgacggaag aaattagaga gtgtctcagc
     5221 cagtttccag ggattcaatt agaagatgat ctagcagcac ataaatatcc gacgagcatt
     5281 cttgctagag gaacagatat ggtttatgtt gggaggatca gaaaagacac ttctttagag
     5341 aacggattgt tgttctatac gactgccgat aacatacgca aaggagccgc tgcgaatgcc
     5401 gtacagattg ctgcagcttt aatgcagaaa atagcggagg tggcaagatg agtaatacgc
     5461 tgaaagtagc gaaattcggc ggaacatcga tgtctcatga agagcaattc aaaaaagtcc
     5521 gtacaattgt tctttcagat cccaatcgcc aagtgatcgt tgtttctgct ttaggcaaac
     5581 gtacgtcaga tgatgacaaa gtaacagact tactttattt gatttatgct taccttcagc
     5641 atcatgttga ttggacaccc ctttggaaaa ggatttgtga tcgtttcatt caagtaagag
     5701 atgttcttgc cctgcagtta cctattgaag atgaactagc acgcatacag aaacaactgg
     5761 aagacgaaaa gataactgaa gattatttag taagtagagg tgaatatctg actgctcaac
     5821 tgatggctga gtatcttggt taccagttta ttgacgcaaa agacctgatt ttctttgact
     5881 atgatgggaa aatcgatcag gaaaaaacag cacaggaaat cacaaaagca tttaaaagat
     5941 atccgaaaat ggttgttcca gggttttacg gggcgaaccc tgcaggaaaa gaaaaattat
     6001 tgggccgtgg gggaagcgac attaccggcg cgatactggc gaagatgttg caagcggaaa
     6061 gttatgagaa ttggacggat gtttcaggaa tcatgatggc tgatccgcga atcatcgatc
     6121 atcctaaaat catcgaggaa atctctttta gagaactgag agagatggct tatatggggg
     6181 ctaacgttct tcatgaagca gctgttttcc cagttcaaga ggctgatatc cccatccaaa
     6241 taaaaaatac caatgatcct ttcgctcaag ggacaaaaat atcgaatcac gaaatagaaa
     6301 aggaaaatgg actgacagga atagctggac gcaaggattt tctttccatc actttattca
     6361 aacgtcatat gtccgatgaa atcgggttta tctggaaagc aatgagcatt tttgctaaac
     6421 atgagatatc aatcgaacat attccttcag ggatcgacaa tatcggagtg atcgtctcag
     6481 cagaagcgat tgccgataag ttatttctca tcacgaaaga attaaaagaa acacttggcg
     6541 tggaagaaat cgtcgtgatc gaagacttag ctttgatctc tgtcgttggg ggtccgcata
     6601 aagaattgat tggattatct gggaaagtgt tatcgatatt gaacaaatta gaaattcgca
     6661 catcgatctt atcacaagga gcacaggagt tgaatctgat catcggtgta ccgaataatc
     6721 aatatgaaac agtagtgaag ggtatctatg aagggatggt gaatacggat gctgaaagaa
     6781 tatcgaatgg cactccatca aattcctgaa atcgggtttc atgaattcaa gacaaaaaaa
     6841 tatttatatg aacaagtaaa aaacagcgag gccgttatcc atgaaatcgg cgaaacagga
     6901 ctactccttt attttgataa tcagcaagaa gaaacgattg cttttcgaac agatatcgat
     6961 gcactgccag tcaaagaaga aacgaatctc tcttttgctt ctaagcatga aggttatatg
     7021 catgcatgtg gtcatgacgg acatatggcg atgcttttag ggttgactga ctttataact
     7081 aaacacattg aggatcttat ttataatgta gtactgatct atcagccatc agaagaaatt
     7141 tccggtggcg cacaaagcgt tattcagtca ggattgttgg ataaatatga agtacaagca
     7201 atatttggct ttcatctatg gcctggacta gctaagggag aagttttctc tcgaccagga
     7261 cctttgatgg cacaaagcag tgaaacagac attatcatta aaggccagtc tgcacatatt
     7321 gcttctagtg aaaaaggaat cgatagtctg gaggcagctg tacgattttt gaagaatgtt
     7381 tatgattttg accggcaatt accggcagag tggaatcatc taatgaaatt tggccaaatc
     7441 caaggtggaa cgatccgaaa tgttttagct ggagaagtta ttgtatccgg aagtatccgt
     7501 tcttacagtt cagatatgca aaattatttg aagaggggat tagaccattt agcagaacag
     7561 tttcactcta cagctactat ttcttttcgc tataatgacg gctatccagc tgtaatcaac
     7621 catagaggct tatatgcagc actgttagat tcaaacaaac tacatgaatt agatgctcca
     7681 gttcttcaag ccgaagattt tggcatatat acgcaacaat atccatgtgt atttttcttt
     7741 ttaggtgtcg gtgatacccc tgctttacat gatccgacgt tcgattttga tatggatgtt
     7801 ttagaaaatg gtgtagaatg gtacaaaacg attcttttta cagaaaatct tcttgtaaaa
     7861 atcgatagca gttcaaaaga ggagcgagta aataatgatg aatttatcca atcgatttag
     7921 tcctaggctt tctagaatag aagtatcaaa aatacgacaa ttcgatcagc aaatatcgtc
     7981 gataccagat gtgatcaaac tcaccctggg agaaccggat tttccaactc ctgaacatgt
     8041 caagcaagca ggaatagcag cgattgaaga agacttttct cactataccg gaatgagagg
     8101 attagaggaa ctgcgggaag cggcttgtat atttcagcaa cagcgttatg gattaactta
     8161 tgatccgcaa acggaagttt tgacgacagt tggtgcaacg gaagcgattg cctctgcgtt
     8221 gttatctgtt ttggaagaag gagacaaggt tcttattcca gcgcctgctt attcaggata
     8281 tcagccatta gtggaactag ctggtgctga attgatcccg atagatactt ctgacacagg
     8341 gtttgtctgt cagccggaac aatttgaacg agcatttgaa caatatggat cagctgtcaa
     8401 agcagtcatt ttaaactatc ctaacaatcc tactgggacg acattgtctg caaaacaatt
     8461 gaaagcaatc gctgaggttt taaaaaaata tccggtattt gttataagtg atgaagtata
     8521 tgctgaattg acttatagtg gaacgcatat gtccatagct acttatcttc cagaacaaac
     8581 aatcgtgata agcgggttat ccaagtcaca tgcgatgact ggttggcgag tgggctttat
     8641 ttttgctcaa aaagccctta ttgacgaact aattaaagtc catcaatatc tggtgactgc
     8701 cgctacaacg atgtcgcaaa aagctgcggc tgaagcgcta ataaatgggg tgaaagatag
     8761 cgagaatatg aaagagcaat atcaaacacg aagagactat ctggtccagc aattggcgcc
     8821 tttaggattt gaagtgaccc agccaaacgg tgcattttac ttgttttgca aactcccagc
     8881 tgccattcaa actgactctt ggcagttttg tgtagaatta gcggaacagg caaaagttgc
     8941 gtgtatccca ggaattgcat ttggcccaga aggagaaggt tatatccgga tttcttatgc
     9001 tagcagcatg gaaaaattac atgaggcctg caaacggatc aaagactttt taacagaaca
     9061 gtgattcata gattttatca aaaaaacaat cgttaatttt gcggtatatt ctgcaaggag
     9121 acgattgttt tttaaattta gttcaaatga acgcgtttct tttgattcat aactaatgta
     9181 atgttaagtt taaattgttt agaatgattt taaaagaata ttcaaggagg tttcatcaat
     9241 ggaaaaaatc aaagttgtca ttgtaggtgc atctcatgga gggcatcaat cgatcttgga
     9301 actattgaca cgatacggtg aaaatgtaga tatcacgcta tttgaagcag gagactatat
     9361 ttccttcatg tcatgtggta tggagctgta tttagaagac aaggtaacag atgtaaatga
     9421 tgtacgtaat ttcagaccag aaaactttcc gcaatccaat gttcatattt taaataatca
     9481 cgaagtaaaa acgatcgatg ccgataaaaa aacagtaacg gttactagcg catcagataa
     9541 cgaaacaaaa gaatatcctt atgacaaatt gattttgagt tctggtgtca aaccaaacaa
     9601 tctgccagta ccaggagcag atctagaaaa tgtctacttg atgcgtggat acaattgggc
     9661 aaccaaaatc aaagaaaaat taaatgatcc ggctattaaa aaaatcgctg tcgtaggtgc
     9721 gggttacatt gggatcgaag cagcagaagc aagccgaaaa gctgggaaag aagtcgtatt
     9781 gcttgatgtg atcgatagac ctttaggcac ttatttagat gctgagatga cagatatttt
     9841 agaacaacac ctaaatgaaa acggtattga agttttgaca aatgcaaaaa tcgaagcttt
     9901 tactggtaac ggaaaagttg aggcaatcaa aacaagtgaa aaagaaatcc cagcagatct
     9961 agtcattcaa gctgccggtg tgaaggcaaa tacagaatgg ttaaaaggga tcgtcgactt
    10021 agatgaacgt ggctggatcc aaacaaatga atacttgcaa acgaatcttc cagatgtgta
    10081 tgcagtagga gatgctacac ttgcttattc tatcccagca cgcaaaaaaa tgccgatcgc
    10141 tttagcgact gttgcacgta gagaagcacg ttatgtagta aaacatcttt ttgaagaagt
    10201 accaaacaaa ccgttcggcg gagtcgtagg ttcctctgca ttaagtgtct ttgactatca
    10261 ttttgcagca agcggattga atagctttac agcagcaaaa gcaggagtag atgtacgagt
    10321 gtcttattat gaagatacgt tacgaccaaa atatgtacca gaagaacaag gaaatccaaa
    10381 agtgtccatc caattattct cggatccaat gacccatcaa ttgctaggag gagcagtatt
    10441 atctacctat gatgttacag gtcaaggaaa tgtattggca ctagcgatcc aaaacaaact
    10501 gactttagaa gaactagcag aagctgactt cttcttccag ccaggctttg accgacaatg
    10561 gagcatgttg aatctagccg ctcaacaagc gttaggagaa gaaccatttg tagaataaga
    10621 aaacgaaata tttgaaaaga ggttgtgaaa aagctgcctt gcatcaagta ataagaacag
    10681 ccaagtaaaa acagcttctt atgtttttaa cttggctgga cttattaccg cagatgcaag
    10741 cttttgaaca ccgtttattt tcaaaaaagg gactgtgaca cgatttgtgt accgaccccc
    10801 aaaagttaga ccaaaaaatc taacttttgg aggtcggtat tttttatggt taaatatact
    10861 tttgaactta aattaaagat cgttcatgat tatttggatg gcaaaggcga ttggaccgta
    10921 aaaatccaga tcaagagatt gaagcggaaa tgcttaaaat tcgggagaag cacaaggatt
    10981 atggctgttt acggatgacc aatgaactaa gaaaccgcgg tttctctatc aataaaaaga
    11041 aagttcagcg cttgatcaag aagctaggaa taaaagtaac ggcatacacg cgtaaatcac
    11101 gtcgctacaa ttcttatcga ggaaaagttg gagcagtagc caaaaatcgg atccatcgtc
    11161 gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa tttaaatacc
    11221 atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat ccttttatgg
    11281 atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat gcattagcgg
    11341 taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat cgtcgtacgt
    11401 ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa ttgaaggagt
    11461 acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca cttatggaga
    11521 atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac tgtttcgagg
    11581 aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg ataaaacaga
    11641 aattaaactg gcaaagtctc gtccaatttc gtaaaacaac cgtaacggtt gtgtaaaaat
    11701 atcattttag agcataaaaa aaaggagtgg atttctccac tccaaaaaag tctaactttt
    11761 gggggtcact acagtgtcac agtccttttt ttagtaaaag gatacatttc ttccttgtat
    11821 attccatgcg tgttcgtgag aaagcatata taatttaatt aacagatagt tagggggaga
    11881 aaaaatgatt ttttcaatta caatgaaact ggtgttcggg ttgatcggtt tattattagt
    11941 ggtacgtttg cttgggaaga aatccatgtc agaaatcaca ccgtttgatt tagtctatac
    12001 gcttgtttta ggtgggatct tagaagaatc aacctatgat gacaatgtcc atgtagggca
    12061 tgtcctattt gccattgcgc tttgggcagt aatgatttat ggtatcgaac gtatcgtcca
    12121 aaaaaatgaa aaggtcaatc gttgggtcaa aggcgagcca tctgttctaa tcaaagacgg
    12181 cgtcatcaac atgacagagt tgacaaataa ccatatcgag atggagcagt tgcgagcaat
    12241 cttaagacag caagaatgct tttttcttga aaatgccaaa catgttatcc tagagaatgc
    12301 cggtcaaatg agtgtattga aaaaatcaga tgaagacaaa gctttatcga tcctgcttgt
    12361 agatgaaggg caaattcagc ataaagtgct tcagtccaat caattgactg aagcatggct
    12421 tatggagaac ttgaagaaag aaggctatgc agatgtaaaa cagctgattt atgttgaatg
    12481 gtcagaagaa aaagggctct acatactaaa taaagaagac gtcatgcatg aatcttaccg
    12541 aatagatgga tagatagaca gaggttgtga aatcagcgcc ttggcttgtt actcaaaact
    12601 aagcgacttt ttcacaacct ctgatatcta atatacgttg ttccagaagt tgcttcttcg
    12661 aaaaataagc caaaattcca caaaaattta agaagcaatt ttcgaaaaat cctttcttat
    12721 tttttgaagt tgatcacttc tgtcacaacc tctcatgtca caaaccattt ttttgtttcc
    12781 tttaactcaa tataccgtac gtcttcccac aatatcggct gatggtcaat cataaagtaa
    12841 tcttcatagg cttcaccaat gaagtgccct tcgacctcat ccaagagtct tccaaattca
    12901 tcttttaaat tgagctgaat gattactgct ttacgagata aaaaggcttc tgtcagtata
    12961 ctatcgattt cttgcaatgt catttgttgt ttaggaagag gctgtttgcg tgcttcttct
    13021 tcattttttt gataccgttg actagttctt ccatcgcaaa agcagtcccc cattttaatc
    13081 caaatggccg atctcgatac tcgttatagt caatgaattt ttttgctgtc cgtctcatct
    13141 tttccacctt ctaatccact cataccacct gcatgcccgc caacgagaga actacgtgcg
    13201 atggcgcgtc ctccttgcaa gagactatgc gcatggatga ttgattgaaa gccgtatttt
    13261 tttctaatcg tatcgacaac aaaatcaact ttcgcttcat ttatctgctt ttcaggatct
    13321 tcaaaaaggt taagctgtaa acctgtcgcg tatacgaggt cggaacagtt cacgcctaca
    13381 cgccgaatat cctggtagtg gtaatgctgg tggaaaatgg tcaataaagc atctgctaga
    13441 tctctgctag catttgtcgc ttcgattttc atttgctggt gaaacccggt cttgccattt
    13501 ggatcaagat agcctaaaga gtatcctacc cataagctga ctacttgtgt ttttgctgca
    13561 gatcgtctca agcgagtgcc gacttggtcg gccatttctt tgataacgat ctcgatttct
    13621 tctcgtcttg tataatctct atctaggatt tgactatttc cgatactttt tgattttggt
    13681 gtatattctt gtcccaaaaa acttcgatcg atgccccaag catgggcata aagctgagta
    13741 ccgatgaccc ctagcttgct tttcaagtga taataatccg cgtgagctaa atcataaaca
    13801 gaatgtatac ccatttgttt cagacgtttt gctgttcgtt tgccgattcc ccaaaagtca
    13861 gtgatatctg agattttcca taacttttct ggtacatctt cataacgcca ttcagcaaac
    13921 atttgctttc cgtcttttga gccattgtct aaggctagtt tagcaagtag cgggttatcg
    13981 ccaattccta tagtcgtgta gattccggtc tgctcaaaca catctttatg gatcagttta
    14041 gccatgtcgt acgcatttgt tttaccaaag agtgccatgc tatttgttac atcaaggaag
    14101 ctttcatcga cggaatagac atgatggttc gcttcgtctg catatttttt atagatagaa
    14161 ttgatttctc tgttcttttc catataatag gccatccttg gggcaacaat atataaatca
    14221 cttggatagg ggaagggaag atctctggca cggctgatat tggtgatgcc gtaagctttt
    14281 tttgctgcag gactggaagc caagattaat ccgctacccc gtgtttctgt cgaatcggac
    14341 ggataggaca tgactactaa tttagttgta aggggatcaa gatccttttc aacgcactct
    14401 acggaggcgt aaaaagattt gcagtcaata cataaaatat ctcttgaagg ttctttttca
    14461 taaacaaata ccggattttg attcgcccac ataacaatca cctcttcaac acaattagaa
    14521 cacacgttct ctttccgtgt caataaaaaa cagcaatttt caaatacgag caaaaggctc
    14581 acatttggaa attgctgaga ggttattttt atctatttgt ttttagctga gatcgttgat
    14641 ttttttatca aacatgaaca gcttctggat cgatctttgt tgtcccattt ccaatgtgtg
    14701 caacataaaa ttccggagca tagccgacaa ctttcatgta ttcatcatag acattgtttt
    14761 tgaaggcagg tatattttct tctttgacaa gagcaatcgc acagccacca aatccagctc
    14821 ctgtcattcg tgcacctaag acaccttctt gtttttgagc agcatctact agtgtatcta
    14881 attcgatccc agttacttca taatcatagc gaagagagtg gtgagaatca tttaacagtt
    14941 gaccaaatgc ttctaagttc ccagcttcta attcagcttt tgccttcaaa gtccgctgat
    15001 tttcagaaac ggcatggcga gctctgcgta tcaatgtatc atcgccgatt tggtcaatag
    15061 ttgattcaaa ttcttcttca tctaagtctc ctaaagaaga gataggcaaa gttttttgca
    15121 aacgtgccaa ggcttcttcg cattcgctac ggcgttcatt gtattttgaa tctgccaatt
    15181 cccgccgctt attcgtattc atgatgacga ttgcataacc atctagtttc actggaacca
    15241 tttcgtattt cagcgtattt gtatctaata agattgcatg atctagctca ccgaagccga
    15301 tggcaaactg atccatgata cctgaattga caccgatgaa ttcattttct acttttttac
    15361 ctgtttggac tagttccaag cgatctgttt ttaaatcaaa cagatcttct aatacaacac
    15421 ctactaataa ttctaatgaa gcgctactgg aaagtcctgc accattaggg attgttcctt
    15481 ccactaataa ctcaaaccca tgatcgattg agtgtccagc ttcttttaat ttaaggacca
    15541 ttccttttac gtaatttgcc cagtttgctt ttttatcata ttctagctca tctaaagtaa
    15601 aactaatgac accgatatcg tcaaagtttg tggaataaac taatatttta ttatcgtctc
    15661 gaggtgctgc tacaccttgc gttccataag tgatggaagc ggggaagaca tggcctccat
    15721 tgtaatctgt gtgttcacca atcaaattga tgcgtcctgg tgagaagtat tgtgtagttt
    15781 ttttaggtcc gaatgtttcg gcaaattttg tgtttaagct tcttttgatt tccatgatga
    15841 gttattcctt tcttgttttg attttgaatt ctgttactgt ttcaaatact gatccggctt
    15901 ttaaatgaat cgaaccaaat gctgagaagc gctctgcacc tggagctgtt tgagtctcaa
    15961 atgtgatgcc accgtgatgt gccagttttc ggttgcgcat ttctggtgtt tctgtgccga
    16021 aatttgcagt gaaaataacc acactagaag catctgtagc aatatctact tggattcttt
    16081 tatcggggct agtcaagcga gcggcttctt tacccaagcc ggtttctttt aagaaaaatg
    16141 gatgatcgat tccgtcaaca agattttttt gatccaaatc actagcaaaa acggacgcta
    16201 attttttagg tatttgaaaa tcgaaagcac ttcctgcagc attttctttt acccctatag
    16261 gaatactatc tgttcgcaaa ggagcataag cttcgctatt gagccaaagc tcatgttgat
    16321 cgattgactg agaagcatct cccgtcaagt tgaagtaaac atgatttgtc ggattgaata
    16381 aagtatcttg gtcactggtg ccgcgagagg tcactcgcca gatattatct tttgtcaaag
    16441 tatagcggat ttccacatcc attgtacctg gaaaaccatg ttctccgtcg ggacttgtag
    16501 tagtaaaaat gacagaagct tcattttcgc cattcaaaat gacataagac cattttttta
    16561 attcaaatcc aggagcacca ccatgcagat tatgtccagt ttttggatct gtggctaatt
    16621 ggtaagtttt tccattgaga gaaaagcggc cattttcgat tctccctgcg gtgcgaccga
    16681 tagaagcacc gatatacgga tctttttcga tatattcttc agcggtgtca aatcccaaaa
    16741 ctaattctcg atcatttgat tttaaactga cgattctagc acctaaatca gagatagaaa
    16801 gtgctagctt gtttttgttc tccaaggtta tcaagtgata accttggcca aaatcttttt
    16861 ctgtaatctt cattttcaag atcctttctt aatgggaagg atctactgca tcgtgaagtt
    16921 catcttccat tgtatcagct ggagccaatt tgttttccaa tttctcaacg atttgtgcat
    16981 gttttttctc tgtcaatgta atcttccaag caaaaataat agcggagaaa atcatcaaag
    17041 cagcaggagc atagaatgca taagctttga aagtcgttac gccatgagca gtgatatcag
    17101 cagcagtagc attaccagtc atcccagaag cgatagcgac aaaccctacg atcccgttag
    17161 acaaagcacc agcgatttta tctagtaaag ggcgaattga tagagtaaca gcttcgttac
    17221 ggataccatt tttccattga ccatattcaa cagagtctgt gatcgtcatc aaagcggata
    17281 agaaaatcaa ttgttgaggg aagtagaaca atactagccc gatgataacg attggcaaac
    17341 ttgaacctgc gatcgtaaag aaaaagtaag aagaaatcat cattgcgatc cctccaaggt
    17401 aaacgtagcg acgagagatg acgcgtgtaa gcattgggaa tagtggaaca gctactaaac
    17461 caagtaaggc agcaactaga ccaacgatcc aaaattcagt tggttggcca agtacatatt
    17521 tgaagaagta gaataatacg gcagttgttg ctgcattggc aatcgcataa gcgatataag
    17581 caagggcaag ccacatcaac tgatcatttt gagcaactgc tttgaacaca tctttgatcc
    17641 cagctttttc attttgctga cggatcgcag tatcgacttc ttttgtgccc aaggcagtga
    17701 taatcgcagt accgcctgaa ataacagcag caatcacacc gaaccagaac cagcctgaag
    17761 cgccttcaat atgtttatga gtaacaagat aggtaaagaa agtaacgata gggacaacga
    17821 ctagagtagt accatttgca cctagagaag agccgaaacg agcaaacgta gcaaattttt
    17881 cacgttcctt tgtttccgta ctcaaagctg gaatcattga ccaaaaagcg atatccttaa
    17941 atgaataaaa actatccaat aagatgaaaa cgattgcaaa taatatgata aataaagtcg
    18001 tattatgagt agctaagcca aagaaattgg taaagattgc taccaagagt acggaactaa
    18061 caacgccgcc gataactaac catggtttga atttaccgta ttttgtacga gtattatcga
    18121 tgatgccacc aatcaaagga tcaaaaataa tttcaactaa gcggatacct acaactaagc
    18181 ttgtaactgt agcaatcatt tttgcattcg ttgccttatc tgttcctgcg aacatctggc
    18241 ttgtcacgaa taccataaaa taagtgctta atgtaacata gaatgtgtcg tgtccaaaag
    18301 cgcctaaagc gtaggacaca cgttggatca ttttgctttt cataatctgt attcctctcc
    18361 tgttcaatat ataatactaa gtaaaccggt tacaacgaat aacaaagatc ttttaatgac
    18421 ttaaacttaa caagaaatcg cttccttttt aatatatttc tgtgactttt atttaacttt
    18481 ttgttgcatt atactaaagg agtaaggagg gatagacgtg gagcaatcga tttttttaaa
    18541 aaaggaacat caacaagtag aaaaagaatt gtattttgat ttttgtggtt tctctaaaac
    18601 gatgccgttt cattcttttg gtcctgctat tcgcaatgat tacatcctgc atgtcgtgat
    18661 ggaaggcaaa ggatcttatc atgtgaaaaa tcaacaattc caattgaaaa aaggtgatct
    18721 gttcttgatt cgtccaggag actcgacgtt ttacttatca gatggagaag atccgtggat
    18781 gtattgctgg ctttcatttg gtgggagtgc tgcagaagaa atcattcggc agtcgctttt
    18841 cagagaagac caatacacga tggtctcttc tgacatacaa aaatatatcg acattatttt
    18901 agaatgcatg aaagatacgg aagaaacctt ggaaaatgaa ttacagttaa cagcattaac
    18961 ctaccgtttt ttatcagtcc ttttaaaaga tggcggaaag gtcagcggtg gtgtacaaaa
    19021 ggttcattcc tctttagctg ttgaaacagt caaatacatc gaggcacatt atgctgaaaa
    19081 attgtctgtt gaggaaatcg cccagcattt agcggtcaat cggagccatt tgtcgcgagt
    19141 attcaaaaat catatgggta ccagtatcaa ggaatatttg atcggggtac ggatcaatcg
    19201 aggggcgttt cttctttctc tgacggatga atccgtggaa agtattgcct atcaagtagg
    19261 gttcaatagt ctagtcgtat ttagccgaat gttcaaaaag agtaccggag aaacggctac
    19321 gaactatcgt aaacgtatga aaaacgaaaa ttttaagaat attgctttgg ataccttgaa
    19381 aaaacagttg gaaaaacaaa ccgcagtttc ttggacaacc tgattagtct ggttaaaatg
    19441 acaagcatcg gcaaaagaaa cttgtggcgg ttatgctaca ctgtaaagcg aagactaaaa
    19501 aggaggaaaa gggatgcgta cacttatcat cattagccat ccaacgatcg aagaatcttt
    19561 aaatcagcaa tttttcaaag aagcttctgc tggtttacca gctacttggc atcatttgga
    19621 atcaagttat ccagacggaa aaatagatat agagactgaa ctacagctct tggcccagca
    19681 tgatcggatc attttccagt ttccgtttta ctggtatagt tctcctgctc atttaaaaat
    19741 ttggcaagat aatgtcttgg aacgagcagc acatgtatta aaagggaaag aactaggaat
    19801 cgtattgaca acaggtgtgg cggaaaaaga ataccaagct ggaggaaaag aagaatatac
    19861 gatttccgaa tttttgaggc cgtatcagcg aatcgcaaat aaattccata tgacctatct
    19921 tccgccattc gttttagcac aatttatgta tttatcccag gaaaaacgtt gggagaagct
    19981 aattgcttat cagcagtatc tctcattgga aggcaaacca tcgctgactc agcggattga
    20041 ctggtttatt caaagagtac aggaaaatca gaaaatgcag gaagaagaat ctgaaaaaca
    20101 agcatatatc gtagaagcac tgactgaggc aaaagagcag atcgaagact tgacctttac
    20161 actgcaagaa atgaaaggaa cttcattatg acaaatgatt ggctgatcca acaattagat
    20221 gaattaagcg aaaaatcaga atatcaagac cgtgcgctct tatatgaaat aaagaaactg
    20281 atggctgaga tagacgaacg aacaatgcag ctgcaaggag aaatcgacgg acaatcttgg
    20341 aatcatctca actggtgaaa ttttcttata aataacaaag ataaaaatgt gcacagcgac
    20401 aattatttgc tacaataaga atatgaagcg tttgataacg ctattataca taaaaattgg
    20461 tggtgaaaaa aatgtatgat gaaaatgagt ggggagaaaa tgttcggatg acccgaagaa
    20521 gacagcaaaa acaggcagct cgtaagcgga tgatcatgat tggggcagca gttgccgtgt
    20581 ttttgatcat agcaggagga gttgcgggtc tatattttca tggaaaaaat tcgtcagaag
    20641 cgaaaagtac gaccataacg gaaacaacga caaagaaaac agagacgaaa caaacaagtg
    20701 agtcatcaac taaaacaaaa gagacacaaa cttctgaaga aaaaacagca aatggtttgc
    20761 cagagcaact tcaagcaatc gtaaatgatt attcgaaaaa gatcgaagaa aagacgcctg
    20821 cattgattga agaataccag acagaaattc agggaaatca agagggaata gctggtttat
    20881 cagcagttgc taaccaaaaa gcacgtgagc ttcaagcaat ctccgacgaa gggatcagaa
    20941 aattacgtgc agcgtatcag gcagcagaaa ataaagacgg tgtagactta gatactttga
    21001 tcaatcaatt atcggctaat tatacgaatc atgtcgctaa gatttccgat atttatttgc
    21061 agactagcgc ctctcttcaa gcagagtcaa caagcacaca agacacaaca tcttctgatt
    21121 ctgagacagc agagtcggta gaagcttctg aaatgcaagc tcgaacaaca caagacacaa
    21181 cagattcctc tgaaactaat accaacagcg cgacttcaca ggctgcgaca accgtagttt
    21241 tggaaggaga aggtccaaat caaatagccg aacgaactgg cgtaccagta gaaacgatct
    21301 tgtcgctgaa tgggatgagc atggagaatt atttcctgac tcccggtgag acgctaaaat
    21361 tgaattgata aaagcaataa aaaagaacga agcttccact aaggtgaagc ttcgttcttt
    21421 ttttattttc cggttctttt ttcgcgtaca aagtaatgga tcgtcatgta aagcaagaaa
    21481 acgagtccaa taatcaatga gattctcgtt tcaggattga taaacatgaa aatcaatacg
    21541 atagctaaaa aagcaagtgt cacataattc gtataaggag atagtggcat tttaaaagga
    21601 tgatcatgca ttttatctgc gtgcttcttt ttgaagcgaa tctcgctgat caaaatcact
    21661 acccaaggaa ccataccagg caaaatactt gagctgtata cgaaaacgaa aatattttct
    21721 gactggttga tgaacattgg tagaagataa tttaagatca gaccaattaa gattccacct
    21781 gagattgcta cgacaggata aaaaggcgca ccgtgacgag atagtttcag aaatttttta
    21841 gacatctttc catttatggc aagtgtatag accatacgac ttgcgctgaa aatccctgaa
    21901 ttgcaacctg ataatgccgc tgtaatcacg acaaaattaa tcagtcctgc agcaaatgta
    21961 atgccgactt tagaaaaagt ttgtacaaaa ggtgaaccaa tctcactcaa ttgattccac
    22021 ggatagatac tcacaatgat aaaaatagca ccaatataaa aaatcaagat tcgaccgata
    22081 gtggactgga cagcttcaat gatcgtcttt ttaggattct ctgcttcacc agcagtcatt
    22141 ccgatcagtt cgattccttg ataggaagca acaacgatcg ataatgcaaa gaaaaatcct
    22201 ttgacgcctc cagtgaagaa tccaccattt ttccaaagat ttgaaatccc tactgcctga
    22261 ccatgattac caaatccaaa taagattacc ccaagacctg caatgatcat caaaatgatc
    22321 gttatgactt tgatgatcga aaaccaaaat tctaattcgc caaacgcctt gacagaaata
    22381 agatttgcca gcataagaaa caagacgaca atgattccgg gaataattgc cggcaaatca
    22441 ggccaccaat aattcatata agatcctaca gcaatcactt cacttattcc tacgacaata
    22501 tattgaaaaa tattactcca agcggtcaag tagccagcca caggatggat gtactcgctc
    22561 gcgtaatttg caaaagaacc agtcgaagga tcaacgtaaa gcatttcgcc taaagcacgc
    22621 ataatcaaat acaaaaagaa tcctgcaatc gcataggctc ccatcactga gggccctgtc
    22681 caacgtatgg ttgaggaggc acccataaac agaccgacac cgatcgttcc acctagtgcg
    22741 atcatttgga tatgacgggc actaagactt cgagttaact tttcttcttc catacaaaaa
    22801 ctcctttcgt tgttgagtca acaagaaaaa ataatcaaac gtttcaacac atgtttttca
    22861 ttattaggtt agccttattg aactcttgat gtgattctac agaaaatttt cataaaatgc
    22921 gaggaaaatt cgaaaaaaac tttttcatca ttctacttga aaatgctttc cattttagtt
    22981 aaactatatt taaataaaaa gttaggtaaa cctaaaaagg agtgtaagat ttggaacgta
    23041 cggccattgt aattcaagac ctttcagccg cttatcaagg gaaaactgtt ttgaaaacta
    23101 tcaacttgac gataaatcca caaaaaatta ccggtattat cggaccaaac ggtgcaggaa
    23161 aatcaacatt tatgaaatct ttgctagagt tgataccagc tactactggt aaagtcacct
    23221 tttctggaca gtcggtaaac tcagtccgta aaaaaatagc ctacgtggaa cagcgaagtg
    23281 aattggatct ttcctttcca attgatgtat taggcgttgt acttttagga acatatccat
    23341 ctttacgaat tggacaaaga cctgggaaaa aagaaaaaga acgtgcaaga caagctttga
    23401 aaaaagtagg gatggaagaa tatgccaaaa gacagatcag cgaactatcg ggtggacagc
    23461 ttcagagagt ttttattgca agagctctag cccaaggagc agaatggatc tttttagatg
    23521 aaccattcgt agggattgat gcgttaagtg aacgaaagat ctttgacatc ttgcaggaat
    23581 tgaagaattc aggaaaaacg attttgatcg tccatcatga tcttcataaa gtagaagaat
    23641 atttcgatga ggttattctt ttaaataaac agctgatcgc ttccggtcca gtacaagaag
    23701 tctttacatc gaagaacctt caattggcct atggtgagat catcagacat ttagtaaaag
    23761 gaggagagaa aaaatgatcc aatcctttat tgatggatta atgaattatc aattcctgca
    23821 atacgctttg gtcacttcca tgcttgtagg acttgcttct ggagtcatcg gttcttttat
    23881 tattttacga gggatgtctt tgatgggaga cgctatctct cacgcagttc ttccaggtgt
    23941 agccatttct tatatgtttg gttttagtta catctttgga gccactgctt ttgggatgct
    24001 aacagcagca gtgattggtt tcgtgactca gcggagccga ttgaaaaatg atacagcgat
    24061 tggaattgtc tttagctcct tttttgcatt agggattatc ttgatttcat atgcccagag
    24121 tgcgacagat ttgtatcata ttttatttgg gaatgtctta gctgttaggg aaagcgattt
    24181 gttgctgaca gcactcgtta gtggaatcgt cttgatattt gtctttttct tttataaaga
    24241 attgaagatc acatcattcg atccgacaat ggcaaaagct tatgggctga acacatcgct
    24301 gatccattat cttttgatgt tctttttgac attagtggct gtagtcagtt tacagacagt
    24361 aggaacaatc ttggtgattg ccatgttgat cacaccagcc gccacggctt acttgctaac
    24421 gaaccattta ctgaaaatga tcattacagc tgcaggaatc ggtatgctaa gtgcagttgt
    24481 cggtgtgttt ttcagttata gttacaattg gccatcagga gctacgatcg tgttagcatg
    24541 taccgcattt tttatccttg cttttttatt ttctccaaca aaaggaattt tatttcagaa
    24601 aggaagcaga tagatgaaaa caaaaaaatc actcttttta atcttggcag ttagtttctt
    24661 ggtattagcc ggttgcggaa agcaggcttc tgaccaagcg gatgaaggaa gtaaagaaaa
    24721 gttgtcagtc gtggctacca attcgatctt ggcggacatg gcaaaagagg tcggaacaga
    24781 tcaaatagat atccacagta tcgtaccagt cggaacagat ccgcatgaat atgaagtact
    24841 accagaagac atcaaaaagg caagcgatgc agatgttatt ttatacaacg gtttgaatct
    24901 tgaaacaggt aacagctggt tcgataactt gatggaaacg gctaaaaaag aagaaggaaa
    24961 agattatttt gcagttagca aaaatgtaga acctctttat ttaactagcg gtgaagaaca
    25021 tacaaaagca gatccccatg cttggctaga cctatctaac ggaataaaat atgtggagga
    25081 aatcgcacgt atattctctg aaaaagatgc agaaaatgcg acactctata aaaaaaatgc
    25141 agaagcatat gtggaaaaac taaaagaatt agatacacaa gcgaaggaaa gttttgcttc
    25201 tatcgaagag aacaaaaaat tattagtaac aagtgaaggg gcattcaagt atttttcacg
    25261 agcatatgat ttgccagcag cttatatatg ggagatcaat acagaaagtc aaggtacgcc
    25321 tgatcaaatg aaagcgatca ttgatcagat aagagcaaaa gaagtaccgg ttttattcgt
    25381 ggaaaccagt gtagactcaa gaagcatgga acgggtagca aaagaaacgg gtttgaaaat
    25441 ctatgataaa ctgttcactg attccatagc aaaagaagga gaacaaggag attcttacta
    25501 tcagatgatg aaatggaata ttgaaacgat ccatgaaggt ttgtcacaaa caaaagaaag
    25561 ctgaaaagtg caaggtctag cttgaggagc agaccttgca ttttttataa gagatatgaa
    25621 aaaaaattat gctgtttttc gtcgtacaga tacctttttt gaagaaattc cgttatagtt
    25681 agagtaagga aggaaggtgt ggctatgaat tttacacgta aagataaata tacgattaaa
    25741 gaagaagtct ttcgattgat cagccagcag gaaaataccg acaaggatca agaccttcaa
    25801 tttcttgaag cagaattagc taaattattc atagcaaatc aaaatgagac aacagaacca
    25861 gatgaagagc tgtacatagg caaatggttg tttgatgaat ttcagccttt agatgaaaat
    25921 accggtatcg gttattttgt gttcctttct ccagtcggct tcacacctgg cgtattagtt
    25981 aaacaaaacg acgaaataac cgtcaaagca tggcctgcat tattttcagt catcaaagca
    26041 gaaggagtaa tcaaaaagat ccagtcggcc tattataaaa gtcaatttat tgccaacagc
    26101 aaattaatga atatgtttta taatcgtcta gtagaaattg ctaggcctgg gaaaatcccg
    26161 caaacattca cgtacacaca gcaaaaaaat ctctatgaag aagtattgta ttcccgcgat
    26221 ctgtctgagt tttcgccatg ggaagaggta aggctccatg aactgttaag tacaaaacca
    26281 gtttcattga atttttttaa tgcattagat aacaaaagaa aattaatttc aacaaattat
    26341 tgggaagtat ttgctgcaag aaaaaaatgg atggaagaaa agaagattgc cgatcagcag
    26401 atccagtttg tccagctgaa aaaagaaaaa ctatattatg ggttatacag ccgttaacag
    26461 caagcgagga agaccatgac attaaaagaa gaaatcatac aagaaagcaa acgattagga
    26521 attgacaaaa tcgggttcac cacggcggaa ccttttgatt cattaaaaga atcgttggaa
    26581 gaacaaaaag cagctggcca tacttctggc tttgaacatc caaatatcga tgagcgtctt
    26641 tatccagaaa tgacatttga tcagccgaaa tcgatcattt ccattgcact tgcgtatcct
    26701 actaggatcc atgaagaagt gcctagggat gaaaaacgcg ggcagtttgc tcgtgcttct
    26761 tgggggatcg attaccatga tatactcaga gaccgtttga accgattgat cgaattcatc
    26821 caaacaagag cagaaaaatg gcaaaaagaa gaggaatggc gtctagctcc gcaagtagat
    26881 actggagaac tgatcgatgt cgctgtagca cagcgagctg gtttaggatt tattggacga
    26941 aacggattgt tgatcactga agagttcggt tcatttgtct atcttggtga gatcgttact
    27001 aatattgtat ttgagcctga taaaccagga gaatttggtt gcggtgactg tatgcgctgc
    27061 gtgactgctt gtccgacaaa agcattgctt ggtgacggaa gaatgaatgc ccagcgatgt
    27121 ttgtcttatc aaactcagac aaaagggatg atgccggaag aatatcgtaa aaaaatgcga
    27181 aatgtcattt atggatgtga tatctgccag ttagtctgcc cttacaatca aggaaaagat
    27241 tttcattttc atgaagagat ggaaccaaaa gtagacgaaa tatatccaaa attaaagcca
    27301 atgctttcga tgtctaataa agacttcaaa cagcaatttg ggcatttagc tggttcatgg
    27361 cgtgggaaga aacctttgca gagaaacgca ttgattgctt tagctaatct aggtgatcga
    27421 acggcattgc ctgagatttc agaatgttta acagatgtcc gccctgacat cagaggaaca
    27481 gcagcttggg ctattggacg tctaggaaca aaagaaccgg aaaaatggct tgatgtatta
    27541 gatgaaatat tagctaaaga aacagaagaa gtcgttataa acgaattgga acatgcccag
    27601 aaattattgc ggagaaagtt aaaataaaaa aatagttaac attattcaaa gtttttgtcc
    27661 agta
//
LOCUS       DADVXB010000024        27510 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.024, whole genome shotgun sequence.
ACCESSION   DADVXB010000024 DADVXB010000000
VERSION     DADVXB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.024"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(161..445)
                     /locus_tag="KB902_000796"
     CDS             complement(161..445)
                     /locus_tag="KB902_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807640.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="KB902_000797"
     CDS             complement(463..1353)
                     /locus_tag="KB902_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBB6807641.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="KB902_000798"
     CDS             complement(1373..1591)
                     /locus_tag="KB902_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBB6807642.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="KB902_000799"
     CDS             complement(1561..3261)
                     /locus_tag="KB902_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBB6807643.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLSFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="KB902_000800"
     CDS             3528..4301
                     /locus_tag="KB902_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807644.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="KB902_000801"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="KB902_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBB6807645.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="KB902_000802"
     CDS             complement(5125..6096)
                     /locus_tag="KB902_000802"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6807646.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="KB902_000803"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="KB902_000803"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBB6807647.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="KB902_000804"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="KB902_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBB6807648.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="KB902_000805"
     CDS             complement(9051..9875)
                     /locus_tag="KB902_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6807649.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="KB902_000806"
     CDS             complement(9848..10528)
                     /locus_tag="KB902_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6807650.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="KB902_000807"
     CDS             complement(10551..11489)
                     /locus_tag="KB902_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6807651.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="KB902_000808"
     CDS             complement(11734..12597)
                     /locus_tag="KB902_000808"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBB6807652.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="KB902_000809"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="KB902_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6807653.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="KB902_000810"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="KB902_000810"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBB6807654.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="KB902_000811"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="KB902_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBB6807655.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="KB902_000812"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="KB902_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBB6807656.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="KB902_000813"
     CDS             complement(19463..20704)
                     /locus_tag="KB902_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBB6807657.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="KB902_000814"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="KB902_000814"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBB6807658.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="KB902_000815"
     CDS             complement(21731..22654)
                     /locus_tag="KB902_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807659.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23393..24679)
                     /locus_tag="KB902_000816"
     CDS             complement(23393..24679)
                     /locus_tag="KB902_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6807660.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24672..25940)
                     /locus_tag="KB902_000817"
     CDS             complement(24672..25940)
                     /locus_tag="KB902_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6807661.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26192..26653
                     /gene="mscL"
                     /locus_tag="KB902_000818"
     CDS             26192..26653
                     /gene="mscL"
                     /locus_tag="KB902_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBB6807662.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26712..27158)
                     /locus_tag="KB902_000819"
     CDS             complement(26712..27158)
                     /locus_tag="KB902_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6807663.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27251..27496)
                     /locus_tag="KB902_000820"
     CDS             complement(27251..27496)
                     /locus_tag="KB902_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBB6807664.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
BASE COUNT         7819 a         5933 c         4775 g         8983 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatgaaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtcgaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    23401 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    23461 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    23521 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    23581 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    23641 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    23701 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    23761 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    23821 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    23881 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    23941 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    24001 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    24061 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    24121 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    24181 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    24241 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    24301 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    24361 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    24421 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    24481 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    24541 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    24601 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    24661 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    24721 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    24781 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    24841 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    24901 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    24961 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    25021 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    25081 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    25141 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    25201 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    25261 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    25321 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    25381 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    25441 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    25501 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    25561 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    25621 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    25681 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    25741 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
    25801 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    25861 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    25921 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    25981 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    26041 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    26101 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    26161 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    26221 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    26281 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    26341 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    26401 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    26461 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    26521 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    26581 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    26641 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    26701 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    26761 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    26821 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    26881 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    26941 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    27001 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    27061 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    27121 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    27181 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    27241 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    27301 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    27361 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    27421 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    27481 ctaaagttgt tggcatacag ttcacctcta
//
LOCUS       DADVXB010000025        25677 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.025, whole genome shotgun sequence.
ACCESSION   DADVXB010000025 DADVXB010000000
VERSION     DADVXB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.025"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            172..516
                     /locus_tag="KB902_000821"
     CDS             172..516
                     /locus_tag="KB902_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBB6807665.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="KB902_000822"
     CDS             517..936
                     /locus_tag="KB902_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6807666.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="KB902_000823"
     CDS             complement(1028..1378)
                     /locus_tag="KB902_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807667.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="KB902_000824"
     CDS             complement(1344..2675)
                     /locus_tag="KB902_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBB6807668.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="KB902_000825"
     CDS             2931..3497
                     /locus_tag="KB902_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6807669.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="KB902_000826"
     tRNA            3642..3729
                     /locus_tag="KB902_000826"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..5037
                     /gene="bsh"
                     /locus_tag="KB902_000827"
     CDS             4063..5037
                     /gene="bsh"
                     /locus_tag="KB902_000827"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6807670.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5362..7257
                     /gene="asnB"
                     /locus_tag="KB902_000828"
     CDS             5362..7257
                     /gene="asnB"
                     /locus_tag="KB902_000828"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBB6807671.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7452..7898)
                     /locus_tag="KB902_000829"
     CDS             complement(7452..7898)
                     /locus_tag="KB902_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6807672.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8126..8275
                     /gene="rpmG"
                     /locus_tag="KB902_000830"
     CDS             8126..8275
                     /gene="rpmG"
                     /locus_tag="KB902_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6807673.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8363..8881
                     /locus_tag="KB902_000831"
     CDS             8363..8881
                     /locus_tag="KB902_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6807674.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8958..9914)
                     /locus_tag="KB902_000832"
     CDS             complement(8958..9914)
                     /locus_tag="KB902_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6807675.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10080..10886
                     /locus_tag="KB902_000833"
     CDS             10080..10886
                     /locus_tag="KB902_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807676.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10883..11872
                     /locus_tag="KB902_000834"
     CDS             10883..11872
                     /locus_tag="KB902_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6807677.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11869..12873
                     /locus_tag="KB902_000835"
     CDS             11869..12873
                     /locus_tag="KB902_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6807678.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13005..13547
                     /locus_tag="KB902_000836"
     CDS             13005..13547
                     /locus_tag="KB902_000836"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBB6807679.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13567..14265
                     /locus_tag="KB902_000837"
     CDS             13567..14265
                     /locus_tag="KB902_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBB6807680.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14286..14498
                     /locus_tag="KB902_000838"
     CDS             14286..14498
                     /locus_tag="KB902_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBB6807681.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14498..15460
                     /locus_tag="KB902_000839"
     CDS             14498..15460
                     /locus_tag="KB902_000839"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBB6807682.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15478..15873
                     /locus_tag="KB902_000840"
     CDS             15478..15873
                     /locus_tag="KB902_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6807683.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16036..16401
                     /locus_tag="KB902_000841"
     CDS             16036..16401
                     /locus_tag="KB902_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBB6807684.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16398..18209
                     /locus_tag="KB902_000842"
     CDS             16398..18209
                     /locus_tag="KB902_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBB6807685.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18271..18438)
                     /locus_tag="KB902_000843"
     CDS             complement(18271..18438)
                     /locus_tag="KB902_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBB6807686.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18686..19675
                     /gene="galE"
                     /locus_tag="KB902_000844"
     CDS             18686..19675
                     /gene="galE"
                     /locus_tag="KB902_000844"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBB6807687.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19687..21171
                     /gene="galT"
                     /locus_tag="KB902_000845"
     CDS             19687..21171
                     /gene="galT"
                     /locus_tag="KB902_000845"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBB6807688.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21195..22175
                     /locus_tag="KB902_000846"
     CDS             21195..22175
                     /locus_tag="KB902_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807689.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22366..23088
                     /gene="tsaB"
                     /locus_tag="KB902_000847"
     CDS             22366..23088
                     /gene="tsaB"
                     /locus_tag="KB902_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBB6807690.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23072..23614
                     /gene="rimI"
                     /locus_tag="KB902_000848"
     CDS             23072..23614
                     /gene="rimI"
                     /locus_tag="KB902_000848"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6807691.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23621..24085
                     /gene="rimI"
                     /locus_tag="KB902_000849"
     CDS             23621..24085
                     /gene="rimI"
                     /locus_tag="KB902_000849"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6807692.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24082..25098
                     /gene="tsaD"
                     /locus_tag="KB902_000850"
     CDS             24082..25098
                     /gene="tsaD"
                     /locus_tag="KB902_000850"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBB6807693.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8329 a         4400 c         5377 g         7571 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggacgggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg gaacaccaga aaatcatttt tcaaaccaga tcagcttgaa tgtttatagt
     4681 cgtgggatgg gaggattggg cttacctgga gatctctctt ctgtttctcg atttgtaaaa
     4741 gccacattta ctaaaatgaa tgctgcatca ggtgattcag aatctgaaag tatcagtcaa
     4801 ttttttcata tactaggctc agtcgagcaa caaaaaggag tatgcgatac tggagaaaga
     4861 aaatacgaat atacgattta ttcttcttgc tgtaacgttg ataaagggat ttattattat
     4921 cgtacgtatg aagacagtca aattactgct gtaaatatga ataaagaaga cttggatcgt
     4981 catgaattgg tcagttatcc agtcataaaa gagcaacaga taaactatgt caattaatta
     5041 atgaatagat ccgtttggta tcatattttc tgatacagtc ataattagac acgatcttta
     5101 ggtcgtgtct ttttttgctg gtttttttgg aaatagcatc cactaatatt tttttaacac
     5161 gaagagaata aggtagcctc aaaaaagaaa acatggtaaa ttagatattg ggactttatt
     5221 ttctgtaaaa acagaaactt tcatcttttg ttttcacgtg acgaaattgt aagagagaaa
     5281 atattcgtcc gctatttatt ctatgataag atgcatatga atgaaataaa cagtaatttt
     5341 atattaggat gtgaaagtta aatgtgcggt attgtaggtt ttgttaacga caaggacaac
     5401 aaaaaaacaa ttattaatac aatgatggat cgaatcgttc accgtggacc taatagttca
     5461 ggagaatata tcgataaaca tgttgcttta ggattcagaa gattaagtat tattgactta
     5521 gagggcggta ctcagcctat ttacaatgaa gatcggacaa agatcattat ttttaatggc
     5581 gaaatctata attaccagcc tttgagagaa gaattgattg cagctggcca cgtttttcaa
     5641 acacatgcag atacagaagt ccttttgcat ggttacgaag aatggggaac agaattattg
     5701 caaaagatcc gcggaatgtt tgcttttgct atttgggata atgaaaagaa tgagttattc
     5761 ggtgcaagag accactttgg gatcaaacca tattattatg cagaaatgaa cggaacattt
     5821 atgtttggtt cagaaatcaa aagttttctg cctcatcctg attttaacaa agaattgaac
     5881 aaagaagcgt tgaaacctta tatgactttc caatattctc cattaaacgg cgaaacattc
     5941 ttcaaagatg tctatcgttt gcctgaaggc cattattata cgtataaaga tggaaaaata
     6001 gacattcagc aatattggga tgcagatttt gaaacaaaag aaacgcattc ccgacaagaa
     6061 tggatcgaaa aaatcgacga aaccgttcaa gcttctattg aagcacatac ggtcagtgat
     6121 gtagaagttg gttctttctt atccagcggg gttgattcca gttatgtaac ctctgtattg
     6181 aaaccagatc attctttctc aatcgggttt gatgataaaa cctataatga agcgattgaa
     6241 gccagaaaac taaccgaact attggactta gataatacag cagcagtgat cgacggagac
     6301 atgtcgttca aagcattccc tttgatccag tatcacttag atgaacctga ttcaaatcct
     6361 tcttgcgtac ctttgtactt tttagcaaat cttgcttcac aaagtgtgcg ggtagtccaa
     6421 tctggagaag gggcggatga actgtttgcg ggataccaaa cgtatggatt ccatacgaat
     6481 tcaaaattca tccgtgtgat tgctcaagga ttgaaaaaat taccaaaagg aacacgctat
     6541 aatttaggac gtaaaatcgg aaaaatgaaa aatttccatg gacggatcca tttatatgaa
     6601 tcacttgctc ctgcaaaaga atattttatc ggtcatgctc gagtgttcga agaatcagaa
     6661 gcatcagaag tgttaacacc aaaatatcaa acagcaccat ctgtggatga aatcatgact
     6721 gttcattacg agaaaacaga aggaatcaaa gatgaagtca ataagatgca atatgtcgat
     6781 cttcatcaat ggatgccaaa agatatcttg ttaaaggcag ataaactttc tatggcaagt
     6841 tctttggaag tccgagtacc tttattggat atcgaagtca tgaaattggc tcaacaaata
     6901 ccaagtaagt ttttattgaa tcaaaacaac acaaaagata ttttcagaca agctgcgaac
     6961 aaacatcttc cggaagaatg gtcgaatcgt gtgaaattag gattccctgt gccaatcaaa
     7021 gcttggttga aagaagaaca cggctacgaa caagtcaaag cattattcga agcagatttt
     7081 gcaaaagaat tttttgatca agaaaaaatc atgaagttgc tagatgacca tcacgaagga
     7141 cgtaaagaag agcaaagaaa aatctggaca atcttcagtt tcttgacatg gtataaagtc
     7201 tactttgtag atgaaacgat tccgcaagca gaagcaatcg actatgtgac tgtttgatga
     7261 aaatcaaata tcaataaaaa agaggttttc tcctaccgtt taacactgag tgataagaaa
     7321 caatttcaaa aaacagctct tcccgtttta tagatattat gacttatggt tcggagttgg
     7381 cagaggaaca ccattgtttc gaacataagg gggttgtgac acgattttcg tcacaacccc
     7441 tttacatatg ttcaataatc gatttctttt tcttttgtcc catctttttt ataaatgaac
     7501 aaagttgatt ctttgttttg tgctacttgc tttccttttt cgattgcttc tttttttgta
     7561 tcaaaatggt tgcttgcctt ttttgcccct ttagatttca cgatccattg ttcttcctca
     7621 tattctacga tcacatctga atcaagcagt tttccagcac gaggattcgt atcgtgttca
     7681 tccgtcttgc ttggattttt ttctttttcg aaagttcgtt tttctgattc actagcatct
     7741 tcataccatt tttttgcttg atcaatggca attgggatcg cacggttatc agggtaccct
     7801 tcatctaata atgcatttgc gatgtcgatt gctttttttc ttgtcaattt atctaagttt
     7861 ttcattgatg caggaaagtc cttcatgttc catggcatat tagtatcccc ctttattaaa
     7921 aaacataatc tatataaaca agtgtaaggg tatttataca aaaagaaaaa gattttgttt
     7981 gagaagtaaa accgttgtat ttatcgtcaa gtagttttac ttaacaaaat cgtgaaaaac
     8041 actagcaatc tagaaaaaat catggtaaga taatcaagtc tgagagtcat cttagaggat
     8101 tcttgtaaaa atgggaggga aaaacatgcg cgtaaacatc actttagagt gtacttcttg
     8161 taaagaacgt aactatctaa caagcaaaaa caaacgtaac aatcctgatc gtttggaaaa
     8221 acaaaaatat tgcccacgcg aacgcaaagt tactttgcac cgtgaaacaa aataatgttt
     8281 ttaaagttct caattccttg ctggtcaaag aattgagact ttttttatct caaaacatct
     8341 aaaatcataa ggagcggata atatgtttat ttccatgtgg gcacaagata aaaatggtct
     8401 gatcggcaaa aatggtttgt taccatggcg attgccaaat gatatgcgtt tctttcgcga
     8461 acacacaatg gatcgaattt tagtgatggg aagaaagacc tatgaaggaa tgggggatct
     8521 ttcacttcct tatcgccata tcatcgtgtt gacaacgcaa ccaaattttc gcacgaaaga
     8581 aaatgcggaa gtaatgcatt cgatcgatga acttttgtcg tatagtcaaa cgatctcaga
     8641 agatatctat gtttcgggtg gtagtcggat ttttcaagaa cttcttcctt acactggtcg
     8701 gatctggcga acattgatcg atagcacgtt tgaaggcgat acgtatattg ggaatattga
     8761 tttttcagac ttcgccctta tagaggagta tgaggggata acggatcaag aaaatctata
     8821 tgcccatcgt tttcaaaaat gggaaagagt aaaaaatagg gttgcttcaa aagaagaata
     8881 aaatctatgc gtctagtttg ttaataagaa aaaaagcatc tcacgactaa tcgtgaagat
     8941 gcttttttta gttaaaatca atttagtttt tctttgatat cattgaccat ttcctgactg
     9001 gcaataggtc cgttatatag ccaactagat tcaggtccga attgcagtac atgattgtct
     9061 gtcactgctt ttagattctt ccagcttggt tcattgaaca tggcagcatc tttgtcactg
     9121 ttcacaagga tgatgtagtc agcatctaat tcagctagct tttcagagga aacagcagac
     9181 cagtcagaag tggctttttt ggagacctct tccactagat caggaacacc aaattccaga
     9241 tcgtcgtata cgattcttcc acttgaccga tttttgctga ccataaaggc tgagttgttg
     9301 gtcacccaca acactgcagc tgtcttgttc tcgattttat ctgctagttc ttctcgagtt
     9361 ttcttgatgg atttttgata atcggaaatg attttttctg cctctttttc ttttgccaaa
     9421 gctttgccga catcttttag ttgttcttcc catgtgacat ctgttccgtt ttttacaaca
     9481 taagttggcg cgattttgct atattgttcg tatttcccgc cttcgacagt agcggaagaa
     9541 gaaatcaaca gcaaatcagg ctcaaagctt aacactttct cataaggaag gtcataagaa
     9601 atcgttggga catcctttaa atcatcttgc agataatctt gaatggaacc actgccaaca
     9661 gtccactggg cgataggttt ttcccctagt gcaatcagat agtcttctaa gtaactgccg
     9721 atgatccgtt tgggcgcgtt tggaatctct actttatgtc caagtgtatc tgtgactgta
     9781 tgagtactat tggatgaagt cgtcgaattg gcagttgtag ctgtttcttt atctgaagag
     9841 ggggagcaag cgctcagtac tccagccagc agcaatatgc tagataatgt gaatactttt
     9901 gtttttaatt tcatttcttt cctcctaaca taattgagaa tctttctcat tggttattat
     9961 tcctgatatt tcgaacgctg tcaaccgctt catttggcta tagatatgaa agtagcgctt
    10021 gacgaaatgt tgaaacagcg tcataattga gaatgatttt cagcgaaagg atgggtgaaa
    10081 tgacgagatt aagagcagct gacattgcag ccggctacga aaacaaaaaa atcattgaaa
    10141 acatgtctgt tacgattcct gaagggaaaa tcactagttt gattgggcca aatggaagtg
    10201 gaaaatctac tttattgaaa agttttaccc gtatactacc tgtgaaatca ggaaagatca
    10261 ttgtcaataa ctctgatatc tctacataca gttcaaaaga acttgcaaaa aaaattgcat
    10321 tattagcaca aactagtgaa caccctacag gtatgacagt agaagaagta gtatcttacg
    10381 gacgataccc ttatcaaaaa ctgttcagtg gcatggacac gcaagatcat gaagcaattg
    10441 agtgggcgtt ggatgctaca ggtctagctg gatttcgtat gcgggatatc gcaacgctgt
    10501 ctggtggaca aacccagcgt gtctggatcg ctatggcgct tgctcaggaa acagatatct
    10561 tgatcttgga tgaaccgaca acatttttag atccggcaca ccaattagag atcctacagt
    10621 tattgactga aatcaatcaa atgaaacaaa caacgatctt gatgtcgatt catgacatta
    10681 atcatgcttc acgtttttca gattatttat tagcaatgaa aaacggtaag ttgatcacag
    10741 aaggtacacc tgaagaagtg atcacaaaag agtgtatgaa aaaaatattt gagattgatg
    10801 caacgattgt cacgcttcca agaacaaata aaccagtttt tctaacctat gatttgttgc
    10861 caaaagagca ggaggatcaa ttatgaggac tatgaagaaa aatagactcc tgcttttggt
    10921 ctgttttgtt cttttgatta ttttttttgt tgctctttca aatggcgcag cgactgtggg
    10981 aaaagcagat ttttggcagg cgttgtttga ttttgataga tcaaaacaaa gtcaccaaat
    11041 catacgaaat attcgtttgc ctcgtgtggc gggagcattt cttgtaggga gttgttttgc
    11101 attgagcggt gcattgatgc aaggagtgac aagaaatcct ttagcagatt caggcttact
    11161 aggaatcaac gcgggtgctt cgttggcaat ggcccttagt tttgcttttt ggcctaaagc
    11221 ttctgatttt tctgtgtttc taatgtcatt ggcaggttct tttgctgtaa ctttgctcgt
    11281 atttggtttt ttgcagtttt cgaaaatggg catgaatcct ttacagctga ttttagctgg
    11341 cgtagctatt agttcttttt ttactgctat cagccaagca cttacccaat tctttaatct
    11401 gcagcaggat cttgcttttt ggtttgtagg cggagctgcc aatatcacat ggaaacaatt
    11461 agcagtattg tttcctttat atatacttgc tgttttggtt tctttttcat taggaaaagc
    11521 aatatctttg attcatttga gtgaaacaca tgcattagct cttggaagtc atcctaaacg
    11581 aacgcggttg attgttttct gtctagttgc agtgttagca gccattgccg tttcgttagt
    11641 cggacctgtt tcatttattg ggctgttggt tccgccagtt gttcgcggaa tggttggaac
    11701 ggactatcgt tatgttctac ctgtctcttt tttagttggc ggtggattgg ttatgttggc
    11761 ggattttaca gcgaggatga tcaatccccc ttttgaaaca ccttttggat tagtcattgc
    11821 attgattggc gttccgtttt tactgataca agtaaggagg gaacaacggt gaaaaaaata
    11881 tattggacgt tctatttctt gctttttgta cttgtcatcc tgtctatagg tagtttaatg
    11941 attggtacgc cttttattta cctggatcag ctttttgcca cgttcatagg gaaagaatca
    12001 tcttctttgg cgctgattgt tagagaattt cgagttcctc gattactgat cagtttatta
    12061 gcaggagctt gtcttggcgt ttctggttat atcttgcaag gagtaacaag aaatgaattg
    12121 gcagattcta gtatattggg cattaatgcc ggagcaggat ttttagtgat gctttattta
    12181 ggtttctttt cgcactattc gctgccgttt ctattgctag ttgtagcctt tctaggtggt
    12241 gttttagctg cttgctgtgt ctatcttgcg gcctatgatc gaaatggctt tttgggtatg
    12301 aatcgaatct tattgtccgg tattgccgtt aatgccggcc tttctgcatt aacattgcta
    12361 tgcacgatcc aattatctaa ggaaaattat ggatttgtga atgcatggtt agcgggatca
    12421 atctggggtg cgagctggcc ttatgtttgg gcattgcttc catgggcggt tatcttaatt
    12481 ccgctaggag gactttatgc acagaggatt gtattgctat catttggtca agaacgcgcg
    12541 caaggattag gccttaacgt ggctaaaagt caaaaaatcc ttttgttgtt agctgttgct
    12601 ttggcaagcg gtagtgtagc ggtgacaggt agtttatctt ttgtaggact actagctcct
    12661 catgctgcga agctagtcgt acgtaaagaa aataactgga cctttgttct gagcggtttg
    12721 ttcggttcca tttttctgct tagtgcagat atggttgcta gagtgattct actaagtggg
    12781 gaagtaccta caggaatttt gattgccctt tttggtgcgc catattttct gtatgcactt
    12841 tttatcagac aaaaacacgc gctgaacagt tgaaattcat taaaaaagga aggccaatca
    12901 tttctaggtc ttctttttat tctatttatg catttatttg aaagttcgat tgctattttt
    12961 ctttttttcc tataccattt tatgagagaa ggaagggtga gtttttggac caattgaaag
    13021 taagattacg ccggaaagga atcgaaaagc tgaaaaatct ggccaaaagt ggcaagaaaa
    13081 aggaaaaaga acagcgaatc tataaacagc tattcgccag cgagtactgg aagtcagcaa
    13141 aagtgatagg gacgacttta tcgaatgaat ttgaactgga tacacagccg gttatccaac
    13201 gagcagaaaa agaacaaaag aaaatagttg tacctaaaac tttgccgaaa cgtcagatgg
    13261 cgttttatga aatggatgaa cagtccgttc ttgtacgttc gagttttggt gttcttgagc
    13321 cacaatcaga gaagctctat ttgccggaga tgatcgatct cctcattgta ccaggtatta
    13381 tctacaatag agccggttat cgaatcggtt ttggcggtgg ttattacgac cggtatttaa
    13441 ataattttca taaaaaaaca tgtagccttg tttttcgtga acaattgaat gaacaatggc
    13501 aaccggagag ctttgatcag aagatccaac aattgtttat tgactaaaat gaaatgggag
    13561 gttttcatga attatcaaca gcaaataaaa ttgcgtgcat ggttaagacg accgttatgg
    13621 acctatgctt ttttagggat acagacagcg gtcttcctca tgatggaatt atttccgcga
    13681 cttgagatcc cttattatgc cggaatgtat ggtccttatc ttgttcactt caatgaatgg
    13741 tggcgtttag tgacaccaat cttcatccat tttggactga tgcatttcgt aatgaactca
    13801 ctgatactgt attttatggg gcagcaaatc gaggcaatct atggccattg gcgttttttc
    13861 ttgatttata tgttcagcgg gataatggga aatacagcaa gctttgcttt taacgaagcg
    13921 aatgttctgt ctggtggtgc aagtacttcg atattcggtt tgttcggtgc gttgtttatc
    13981 ttagggtttc attttaaaca taacccagcg atccagcagc tagtcagaca ttttctttta
    14041 tttattgtgt tgacatttgt ttttggtctt ctggatacct ctgtagatgt ttggggacat
    14101 gtcggtgggc taattggcgg attagtgtta gggaatgttt tgggtctacc gaaacaacag
    14161 acaagctatt cgatacacca aaggattctt tctacactag tttttgtatt tctttttgta
    14221 atatgtattt tactgggttt aaaaaaatat ggtttacttg tataatatga aggaagtgct
    14281 taaagatgga gagcttatat gatgtacagc agctgttcaa aaaatttggc atctttatct
    14341 atgtgggtgc acgcatctat gacattgaat taatgactat cgaattgcgt aatctgtatg
    14401 atagccgttt gattgatcat gatacataca tgacagcgtg gcgcatatta aaaagagagc
    14461 accgaattga agaaagccga aagaaaggaa atttgtaatg gacaagaaga ttattgggat
    14521 tgatttaggt ggaacaacag caaaatttgc aattttaaca ccagaaggag agattcagca
    14581 aaaatggagc atcgatacca atattttgga tgatggtaag catatcgttc ctgaaatcat
    14641 tgaatcaatc aatcatcgtt tgaatttata taatatgaaa gccgaagact ttatcggaat
    14701 cggcatgggt accccaggaa gcgtggacag cgaagctgga acggttattg gtgcgtataa
    14761 cttaaactgg acagaagttc aatttgtgaa aaaactgatc gaggcaggaa caggaatcaa
    14821 attcgctatc gataatgacg cgaatgttgc tgctttaggt gaacgatgga aaggtgctgg
    14881 agaaaacgat ccagacgttg tattcgttac tctaggaaca ggtgttggcg gaggtatcgt
    14941 tgctggcgga aatttgattc acggcgtgag cggagctgga ggagaaatcg gacatatcac
    15001 tgtggatcct gaagggttcg aatgtacttg cggtaaacgc ggatgtttag aaactgtatc
    15061 tagcgctaca ggtgtggtac gcctaggtcg tttcttggca gaagaatacg caggggattc
    15121 aaaactgaaa gcaatgctag acaacggaga agaagtaaca agtaaagata tctttgaaat
    15181 ggctcaagaa gacgatccgt ttgcattgat ggttgttgat cgcgtatgct tctacttagg
    15241 tttagcttgc ggaaacttgg ggaatacatt aaatccgtca agtatcgtgt taggtggagg
    15301 agtatcggca gcaggagaat ttttacgtag ccgtgtagag aaatatttta aagaatttac
    15361 tttcccgcaa gtaagagaat caacaaaaat caaattagca gagcttggta atgaagctgg
    15421 tgtcattggt gctgcctcat tagccttgaa atttgcttaa aaaaacggag gcattacatg
    15481 gttttatggg taattaatat cattttgcta ttgattgtgc ttgcaatcat cctttgggaa
    15541 gtctatctac gagtaatggc caaacgttca gcaacgactt tgacagaaga agaatttcga
    15601 gaaggaatga gaaaagcaca agtaatcgat gttcgcgaaa aagatgtgtt tgatgctggg
    15661 catattttag gtgcaagaaa catcccttac actgttttga aagattcatt aggatctatt
    15721 cgaaaagacc agcctgtcta tatttacgat caaaagaaaa gtttgagcat ccgtacagca
    15781 aataaattac gtaaagcagg ttatcaagag atttatttac ttaagggtgg atatgacgga
    15841 tggtctggaa aaatcaaaag taaaaaagta taaaacagat gattgtatga cagctttaaa
    15901 aaccgaatca atcattagat tttgaccaag atcacatgaa cggcgcaatg gatagttgtg
    15961 ccgttcattt tttttatttt gtgctattat ctacatatat aagctaagcg aaaaggtaga
    16021 aagaaggaaa caactatgat caaattaaaa cgtgtttacc ttgatgctga aaaagaggat
    16081 ggctatagaa tactcgtgga tagattctgg ccacgaggaa tttcaaaaga aaaagcgcag
    16141 ttagatctgt ggttgaaaga aattgcacct agtaatgaag cacgcaaaac ttttgaccat
    16201 gtaccagaac gatttgcttc atttgcaaag aaataccagc aagaattgat tttcgaagaa
    16261 gaaaagaagc aagctatttt taaactcagt caacttatga aagaacatcc agtcattact
    16321 tttgtttatg gtgcaaaaaa tgaacatcag aaccatgctg ttttattgaa aaaatttatc
    16381 gaaatggagg catgcaaatg aaaataggga tcattggtgc cggacctaga ggattaagtg
    16441 tagcagaaag gattctccat aataatcagg acagacattc tcttgaactt tttcttttcg
    16501 atcccaatgg tcctggaggt cgagtttggc ggttgaatca gccaccggag ttattaatga
    16561 attctgtttc tcaacaagtg acgcttttta cagatgaaac attgtccagt ggaggattgg
    16621 taacacaggg acccaacttg tttcaatgga gtaaaggacc tgctacagat tatatcgaac
    16681 agacggtaac caaaaataag caactaatta tagaagaaat caatcgtctg gaaaaagatc
    16741 agcaatctac tcgatgttta tacggactct atcaacgctg gtttttctca aagttgcaag
    16801 aagaatttcc agcttctatt cagtttgttt attctttagt aaaaaaagta agcaaaagaa
    16861 aagatggtta tcttttacag acagatcagc aaagctattc tatcgatcag cttgttttag
    16921 caagcggtca ctgggaaaat gatgagacag aagaagaaag agtgtgggta gactacgcaa
    16981 agaaaaatgt tttactgtat cagcttcctt ctaatcctgc agatgtagat ctttcgaaga
    17041 taccgcctaa agaaaatgtc tttttaagag gtctaggctt aagttttttt gattatgtcg
    17101 gattgtttac agtatcaaga ggagggcgct tcgagaacga aaagggaaaa ctggtctatc
    17161 atccatcagg caaggaaccg attgtataca gtggatcaag aagggggctc ccttattacc
    17221 ctcgaggaag aaatcaaaag caaggcggag caatggcatg gccacggtta ctaacaaaag
    17281 aaaacctgga gcaatggcat cagtcgggat ttttgactgg cgaaacattt tttgactatc
    17341 tgaaaaaaga cgttgagttg ttttattaca agaaaatcat cgaagaatat cacttgccga
    17401 ttccaaagaa aaattttgag catgattttc tctccctctc ttcagaggag tgtctcggaa
    17461 agcatccagc actaatccct tatagatggg attggtcgta tttagaaact cctcttgcct
    17521 atcagaatga gcccttttca gaagctagcc gaatatttat tgaagggcag ataaaagaag
    17581 cggaaaaagg caattgcaca ggagcatttg cttcaacatt tgatgcatta aaagactggc
    17641 gtgatccaat ccggcaggct attgaatggc acgttttttc tgctaaggaa tacaaagaaa
    17701 tactatgggg atggtttact catctaaata gctttttaac gatcggtccg ccaatcattc
    17761 ggacgaaaga attagcagca ctgatagatg cgggtatttt tcatttgatc gaaccgccat
    17821 ttgatattca gcaaaagcac aaccgctatg ttatttctct acaagataaa gaaatcagca
    17881 gtcgctattt gattgaagct cgattgccac aaacaagctt ttctcgttca agtaatcctg
    17941 tcataaaaaa tttgaaggaa aacaaacttg ttcgcccttt ttcattttca gataatacag
    18001 gaagttatca ttcagaagct atagatgttg agcgaggtac gaatcgcgtg attgatgctt
    18061 caggggaaat ccagtctgac ttttattgct atggaatacc tgttgaaggt gtggattggc
    18121 taactgcagc agtagctaga ccttatacag atccatggaa tctgagacag gcagataaaa
    18181 tagcacaact tatattgact gacaaataaa aatacgcatg atgacttatc tgttttttag
    18241 aaagtcttca tgcgtatttt taaataatta ttaacgagaa acgcgtttac gcattgcttt
    18301 tttacggttt tcttcgatca ttgcttcttt ttcgtcaatt ggatcgatca ctgttttttt
    18361 cacagaagca accaaaccag caacggcagc ggctgttgcc agacttccta ctaatattcc
    18421 agatacaaat tttttcattg aatccacctc atttattatt tgttatatct attatggaac
    18481 aaaagagaaa aaaaggctag ttttacgttt gtttgtaaac ctttgcaaaa aatccttgaa
    18541 aatgtttact aaatgtttta ttataaattt accatatgaa tttacgaaat tttactttgt
    18601 ttgttttcac cataaaagta aacttcgttt tttaaattat atagaatcaa caaacacaat
    18661 tttactaatc aaaggagtgt tttttatgac aattttagta ctaggcggag ccggttatat
    18721 cggttcgcac gctgtagacc agctagttca aaaggggtat caagtagctg tggtagataa
    18781 tttgctcaca ggtcacaaac aagcagtaca tccagatgct catttttatg aaggagacat
    18841 ccgggataaa gaatttctac gttccgtatt tgaaaaggaa ccgattgaag gagtaatcca
    18901 ttttgctgca agctctttag taggagaatc tgtcgaaaaa ccattgatgt atttcaacaa
    18961 caacgtatac ggtatgcaaa tcttacttga agtcatgcac gagttcaacg tgaataaaat
    19021 cgtattctct tctactgcag caacttatgg agagccgaaa gagtctccaa tcacagaaga
    19081 tacaccagct aatcctaaaa atccgtatgg tgaaagtaaa ttgatgatgg aaaaaatgat
    19141 gaagtggtgt gaccaagcat atggcatgcg ctatgtcgct ttgcgctact tcaatgtagc
    19201 cggagcaaaa gcagatgcat ctatcggaga agatcataca ccagaaacgc atcttgtccc
    19261 aatcatttta caagtagctc ttggtcaaag aaaagccttg gctgtttatg gagacgatta
    19321 tgatacacca gatggaacat gtatcagaga ttatgttcaa gtagaagatt tgattgctgc
    19381 acatatttta gctttggaat acttgaaaga aggaaatgaa agcaacttct tcaatttagg
    19441 cagcagcaaa ggatactcag tcaaggaaat gctagaagca gctagagaag tgacaggaaa
    19501 agaaattcca gcagaaatag caccaagaag agctggagat cctagccgat tagtcgcttc
    19561 aagtgaaaaa gcgagagaga ttctgggctg gaaacctgaa tacacagata tcaaagcgat
    19621 tatcaaaaca gcatgggatt ggcatgtcag ccatccaaat ggttatgaag aataggggaa
    19681 tgagatatgt caatcagtca aacgatttgt gattttgcca cacttgcgat cgaagctggc
    19741 ggatggatgg aaatggaccg cttatattta cagaatcgtc ttttagggat ggtaggagaa
    19801 gatgctctag aaagcattga agtaagacca gttaaggaag aatctgtaga cttattggat
    19861 cagcttgtcg ctaaggcaag agaaaatggt gttctttcag aattgccagc agaacaagag
    19921 atttttgaag cgcaattaat ggattttctc acaccgccac cttcagtcgt caatgcattc
    19981 tttgcacagc actattcgaa aagcccagag gaagcaactg agtatttctt taatttaagt
    20041 aagaaaaatg actacatcaa aacaagagcc atcgcaaaaa acatcaaatt tccggcagag
    20101 tcggagtatg gtgaactgga aatcacaatc aatttatcta agccagaaaa agatccaaaa
    20161 caaatcgcag cagaacgcga ggcggtaaaa gtagactatc ctacctgcat gctttgcatg
    20221 gaaaacgaag gatatagagg tcgcttgaac tatccagccc gcaccaatca ccggattatt
    20281 cgaatgaatc tagacggtga aagctgggga ttccaatatt ccccttatgc ttattacaat
    20341 gaacattcga tcattttatc agaacaacac cgcccgatga aaatcacaaa ggaaacattt
    20401 gctagactgc ttcggattac tgaagtcttg cctcattact ttgttggttc gaatgctgac
    20461 ttaccaattg ttggaggatc gattctttct catgatcatt atcaggcagg acgtcatgaa
    20521 tttcctatgg caaaagcacc gatagaaaaa cttatcaaac tagaagatta tccgcaagtc
    20581 atcgcaggag tcgtgaaatg gccgatgtct gtgatccgtt tgcaatcaac agagaaaaac
    20641 ttgcttattg aagcagctaa ctcagtattg gaaaaatgga aagcatattc ggatgaaaca
    20701 gtatctatca gagctttttc agcagatggt acaccacacc atacgattac gccaattgca
    20761 cgaagaaggg acaattactt tgagttggac cttgtccttc gagacaacaa tgtttcagaa
    20821 gaacatcctg atgggatttt tcatccacat aaagatgtcc aacatatcaa aaaggagaac
    20881 attgggttga tcgaagtaat ggggcttgct gttttaccac ctcgtttgaa accagaacta
    20941 gtagaagtag agcatttctt attaggagaa gaaaaccaga tggctgaata tcatcgtccg
    21001 tgggcagaac aattaaaaaa agaacatcct gatttgacga aagatacggt caccgatgtc
    21061 gtacaaaaat ctgtaggtca ggtttttgca cgtgtactgg aagacgctgg agtattcaag
    21121 cgagatgaaa aaggacaggc agcgtttgaa cgatttactg cgattttata aacgtaaaaa
    21181 aggaggagag acaaatggca acaattaaag acattgcgca gttggcagga gtttctcctg
    21241 ctactgtttc aagagttctc aactatgatc ctgatctttc cgttggctta gccacaaagc
    21301 aaaaaatttt tgaagcagca gaacgcttaa attatacgaa acatcgtaaa aatgcagcaa
    21361 atactaagca aacgcttcgc ctgatccagt ggtacgacga tacggaagag cttgaagatc
    21421 tttattattt atctattcgc ctaggaatcg aaaaaaaggc agaagaagca aacgttactt
    21481 tattgaaaga aacgtgggat tccattagtg atcttccggc agatggaacg atcgcactag
    21541 gaaaattcga cgaagctcag ttattagaaa tgaaaggatc ccaaaatgcc ttgcttttgg
    21601 tagattctga cggcacttct caaggaatcg actctctagt tgtcgacttt aagtcaagtg
    21661 ttcaaaaagt cattgaacac tttgtctccc ataaagcgca acatatcgct atgcttgctg
    21721 gaacagaata tacgaagaaa aaccatcagc ggctaaaaga tcccagaatt atggcatttc
    21781 aacaagtttt ggcagaaaaa ggctacgacg aaggtccaat tatcgaagca gatttttctg
    21841 tcgagtcagg atatcaagca gtgaagcagt atttaaaaac gaatccgcat gttcctgatg
    21901 cgctttttgc agctaatgat gcattagcga ttggcgcact gaaagcgatt caagaaaaag
    21961 gtttagtggt accagaagat atttctgtga tgggcttcaa tgatgtcagt gtagcgaaat
    22021 atgtaacgcc ctcgctttct actgtaaaag tttataccga atggatggga gagctagcag
    22081 tggagacgat tcttcaatta agtaattcca aagcaccggt ttcaagaaag attattgtgg
    22141 aaacagagtt gattattcga gaatcaacga aataaaagat ggaaaagctg tgggaaaatg
    22201 gagtgatacc gcagcttttt tgtgtttcag gaaggggcaa aatttgcccg ccagcagata
    22261 atcatgtatt attgtactag ttttgccttt ggtattttca tcctcagaat aaaaaagtat
    22321 gctacaatgg aaggcgagaa tgtcatagca gaaaggatca aatatatgat tacattagga
    22381 atagatactg caaaccaaac tttggcgatc ggtgtggtag aagacgaaca aattcttgga
    22441 caaatacaaa caaatatcaa acgcaaccac agtgtaacac tgatgcctgc aatcgaccaa
    22501 ttgtttgcag atcttcaaat aagtccaaaa gacattgacc gaatcgcggt ttctgatggt
    22561 cccggttctt atacagggct tcgtataggt gtaacgacag caaaaacgat tgcttataca
    22621 ttagataaag agctagtagg agtatctagt ctgaaaacca tcgcggctaa ttgcatcggt
    22681 gtggataata ttattgtgcc catgtttgat gctcgaagaa aaaatgtata cgctggggca
    22741 taccgctgga aagaaaatag attagaaact gtacttgaag atgtacatat ttctgcttct
    22801 gatttgttca cacaactaca aaagctgaat gaagctattt atttcgtcgg gagtgattgt
    22861 cacaaattct tctctgaaat aaaggaaata ttgcctagtg cgatgattaa tacagttcca
    22921 gcatgggata ttccaagtgg tgtaactgtg gctcaattag gtgctttagt tgaaccagtt
    22981 gcagagaaac aagcttttct tcctcgctat ttaaaacgag tagaagcaga agaaaaatgg
    23041 ttggagacgc acacacctgg agacgaaagt tatgttgaaa aaatttagag cgtatgccag
    23101 aagctttttt caagataaaa tgatttatac agaaaaaaca gtcgaacaaa tcgatcgtcg
    23161 ttacgtacta agagaattga ctacagaaga tatcaaagag ctgctggatg tcgaacgaga
    23221 agtctataat ggcgaattgc catggacaaa aagtgccttt atatcagaat tgaagtcacc
    23281 gcttcctcat ctatatctag gtatctttga taatggaaga atgattggtt ttatcggttc
    23341 aagagcgttc ggtttagatt gccatatcac gaatattgcc gttcgaccgg catatcagcg
    23401 taaacgaatc ggttcgctgc ttattgacga aatcgagaac tttgctataa tgaatcgctg
    23461 tgagacgatg tcattagaag tgcgtatgag taatcaagat gcacaaagac tttatcggaa
    23521 attggggttt caagcaacaa cgatcaaaaa aagatattac actgaaacaa aagaagatgc
    23581 gttggatatg ataaaacttt tagaaaatga gtgagattag ttgatttgca gaaaaaaaga
    23641 ttttgatgaa gcgtacttgg cagaatgcgt atggatgatt agcgaaaatg cttatccaca
    23701 tggttcacct tggacgaaaa tgcagttttt ggcagacatc caacagcctc actctgatta
    23761 tctgctttta gctgaagata accagatctg tggctttatt ggatactcga aagtaataga
    23821 tgaagtcgag atcacaaata ttgctgttgc agtttcagaa caaggaaaag ggcatgcacg
    23881 gcatttgtta caattactga ttacggaaca aataaaagat tcgctgcatg tttttttaga
    23941 agtacgtcta tctaatgaag cagcaagaaa actttatgaa tcagaaaagt ttcgtatatt
    24001 aggtaaacgg aaatcatatt atcgcaatcc gacggaagat gcgatcatta tgagcagaaa
    24061 gttaaaaacg gagacgatga aatgaatgaa gaattgattc tggcgattga atcaagttgt
    24121 gatgaaacga gtgtagcggt cgttagaaat ggaacagaga tcttatctaa catcgttgct
    24181 tctcaaataa acagtcataa acgttttggt ggcgtagtac ctgaagtagc tagccgccat
    24241 cacgtagaac aaatcacctt atgcttggaa gatgcactgg tagaagctgg tgtgtcggca
    24301 gaagatttat cggcagtcgc tgtcacttat ggaccaggac ttgtcggctc gttgctgatt
    24361 ggtatttctg cagctaaggc ttttgcttgg gcacaccaat tgccgcttat tcctgtaaac
    24421 catatggcag ggcatatcta tgcagcccgt ctggttaaac cattccagtt tccattgatg
    24481 gcacttcttg ttagcggagg acatacagaa ttagtctata tgcaagaaga tggatcatat
    24541 gaaatcattg gggagacaag agatgacgca gcaggagaag cttatgacaa agttggaaga
    24601 gtattaggtc tttcttaccc aagcggaaaa gaaatcgatc agctagctca tcagggaaaa
    24661 gataattacc attttccgcg agcgatgatc catgaagata attatgattt cagttttagc
    24721 ggattaaaaa gtgcatttat caatttggtg cataatgcac aacagcgtgg agaagatcta
    24781 gacaaaaatg atttagcagc tagctttcaa gcaagtgtga tcgatgtatt gattactaaa
    24841 acacttcgag cttgtcaaaa ttatccagtc aagcaactga ttatagctgg aggtgtagcg
    24901 gccaatcaag ggttgcgtga aggattgcag gatgctttgg caactaaact ccctgaggta
    24961 gaactagtga ttccccctct tcgactttgt ggagataatg ctgcaatgat tggagcagca
    25021 gcacatgtgg aaatgcaaaa aagaaatttt gctagctatc agttgaatgc tgatccaagc
    25081 ttggttttat ctgaataaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    25141 gcccaggaaa aacggcttct catgtttttg acctggctgt tcttattacc gcgtatgcaa
    25201 gcttttgaac gccgtttaat caagagttcg taagcctgtc gtttaactct gattcacaag
    25261 gaacaatttc aaaaaacagc tcctcatgtt tatgaacatt atgacttgtg accgaagagt
    25321 tgacaggtac acaccgttta atcgaaatag ggctgtgaca cgtttttgtc aaagccctat
    25381 tttttacata cttttaatca ttattgttat tttgctattt tttacagctt atttatcatt
    25441 atccgttcct ctgattgccc tcactgagta atcgtttatt gtcgaggaat atcgaataat
    25501 ctagatcgga tgaggacaag acgcttcatc tagttaatct aacagtattt tttgcaaaca
    25561 gtgaatatta cataactgaa acacacatag aaaatctttg agtcttgtcc agtgatctaa
    25621 aactgccgga tctttcagaa gttttaggga ggaaaataag cagtgaccct gatattt
//
LOCUS       DADVXB010000026        25491 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.026, whole genome shotgun sequence.
ACCESSION   DADVXB010000026 DADVXB010000000
VERSION     DADVXB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.026"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            83..2143
                     /locus_tag="KB902_000851"
     CDS             83..2143
                     /locus_tag="KB902_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBB6807694.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2226..2795
                     /locus_tag="KB902_000852"
     CDS             2226..2795
                     /locus_tag="KB902_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6807695.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(2970..3776)
                     /locus_tag="KB902_000853"
     CDS             complement(2970..3776)
                     /locus_tag="KB902_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807696.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3914..5428
                     /locus_tag="KB902_000854"
     CDS             3914..5428
                     /locus_tag="KB902_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBB6807697.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5831..6814)
                     /locus_tag="KB902_000855"
     CDS             complement(5831..6814)
                     /locus_tag="KB902_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBB6807698.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6819..7466)
                     /locus_tag="KB902_000856"
     CDS             complement(6819..7466)
                     /locus_tag="KB902_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6807699.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7551..8183)
                     /locus_tag="KB902_000857"
     CDS             complement(7551..8183)
                     /locus_tag="KB902_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6807700.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8199..8750)
                     /gene="coaC"
                     /locus_tag="KB902_000858"
     CDS             complement(8199..8750)
                     /gene="coaC"
                     /locus_tag="KB902_000858"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBB6807701.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8747..9484)
                     /locus_tag="KB902_000859"
     CDS             complement(8747..9484)
                     /locus_tag="KB902_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBB6807702.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9481..10470)
                     /locus_tag="KB902_000860"
     CDS             complement(9481..10470)
                     /locus_tag="KB902_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6807703.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10728..11270
                     /locus_tag="KB902_000861"
     CDS             10728..11270
                     /locus_tag="KB902_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6807704.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11287..12372
                     /locus_tag="KB902_000862"
     CDS             11287..12372
                     /locus_tag="KB902_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807705.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12384..13190
                     /locus_tag="KB902_000863"
     CDS             12384..13190
                     /locus_tag="KB902_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807706.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13191..14018
                     /locus_tag="KB902_000864"
     CDS             13191..14018
                     /locus_tag="KB902_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807707.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14015..15088
                     /locus_tag="KB902_000865"
     CDS             14015..15088
                     /locus_tag="KB902_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6807708.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15516..18212
                     /locus_tag="KB902_000866"
     CDS             15516..18212
                     /locus_tag="KB902_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6807709.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18289..18777
                     /locus_tag="KB902_000867"
     CDS             18289..18777
                     /locus_tag="KB902_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6807710.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18789..19283
                     /locus_tag="KB902_000868"
     CDS             18789..19283
                     /locus_tag="KB902_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6807711.1"
                     /translation="MIKSVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19304..20113
                     /locus_tag="KB902_000869"
     CDS             19304..20113
                     /locus_tag="KB902_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6807712.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20110..20931
                     /locus_tag="KB902_000870"
     CDS             20110..20931
                     /locus_tag="KB902_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6807713.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            20982..23081
                     /locus_tag="KB902_000871"
     CDS             20982..23081
                     /locus_tag="KB902_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBB6807714.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23078..24196
                     /locus_tag="KB902_000872"
     CDS             23078..24196
                     /locus_tag="KB902_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6807715.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24235..25113
                     /locus_tag="KB902_000873"
     CDS             24235..25113
                     /locus_tag="KB902_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6807716.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25304..25456
                     /locus_tag="KB902_000874"
     CDS             25304..25456
                     /locus_tag="KB902_000874"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6807717.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8045 a         4439 c         5406 g         7601 t
ORIGIN      
        1 tttgatttta tttatataat gaaatcatct tatgaaaatt actacttcat gtttagacaa
       61 gagtagggag gactaagaat aaatgtgttc aaaaagacgt tcaaaacaac taaataaaca
      121 cgcttgtcgt ttagataagg aacggtcgtg ttctgaaaaa cactacgtta agtttatgat
      181 gcgcacgatg ctgatcagtt tatctgtagg tgtctatatg catgtacccg ttcaggcaac
      241 gacacaaacc atcaaggtcg tacgtacctc tgtttctgag accactgatt cccctatcac
      301 tattactcat actttcactg atgcaaatgg aaaacagcta cttcctgcat tgacttccta
      361 taataaagtc agttatcctc caacgataaa ccactactgg ttaattccta acaaaacatt
      421 atggacatcg gaaaccggaa gcagtgtgcc gctttctatc ttttccgata tgactgatcc
      481 tacaaaaggt gatcagttaa aacagatcac tgatattttg aatcatgctt tgacagatat
      541 aaaggacggt ggaagcgcac aagtttctta tgtatatgaa aaagattatt cacagtttga
      601 aagaaagaaa atcgatgttc tggcagggac aaaagtttcg atatctgatc tggtagaaag
      661 gctgaagaac gcagatggaa cacaaggaga tatgtccaaa gtaatttcaa acaatgggaa
      721 tatcgtggat acgactaata caggaacatc tactatttcc ttgtcctatt ttgatccaat
      781 tgctttaaaa acaatgactg catctgctgt gatccatgtt cgtgctgatc aaacagctat
      841 caaaggaaaa gatcttcact taagaacagg agagagttac gcccctaaag atcttgttga
      901 atatgtaaca aaaagcgatg gaacttcagg aaataaagaa gaaatcaaaa tgaacgggac
      961 agtagatact acaactccgg gagaatatcc cgttgtatta acttatatag actcgaaaac
     1021 atcaaatgtg gcagaaacaa cagctgtagt ttatgtagaa gcatctgctg cttcatcgac
     1081 tgtcatcact cattttatag atagtcaaac aaataaagaa cttcaagcag aaacacatat
     1141 gagtagtgta aatcgtattc ctgatttgcg cctacctgct gaattttctg atcgagtgcc
     1201 aaatatagat ttatcgactt atgaacaaaa tgggaaagtc acttctattt ctgattggat
     1261 gcaagcaaac ggattagaca gaaaaagtca ctggtcggag atccttgaag tacttcactc
     1321 agaactgatg aataatagga agcaatcagg aggggaaatt acctttactt atgtttatat
     1381 accagacaat cgttcattag aaggtcatga tcttattgtt catccaaacg aaaaaataaa
     1441 caaagaagag ttgatccaat cagcaacaaa ttccttaggt aaacccgtac cgttaaagga
     1501 tgtatcggtt acaatcaatg aagtaccatt ggaggatggt tatttgacca aacaaacagg
     1561 tgattttacg attatgtata gttatcatga cccgtattca ctccaagaac tccatgctca
     1621 gtcactatta catgttttac cattaaacaa acagatagat caaaaagaac aaaaaagaca
     1681 agaagaaagc ttgtcagaaa aaaaacaaca aatggctcat gcagtttctc caacagggaa
     1741 agtaaaacaa acaagaagcc tagagttagc aagaatatct agaaaaatct cagaatctaa
     1801 taaaacgata aggcaagaag ctcatttggc cccacaagtt tctggattgg aaaatgaaat
     1861 tttagagcct aaaataaaac aacaatcaga aaaagaattt gttgctaaac agtcggaaga
     1921 tcagaaggaa tcagatgacc agaaggaaac gaagaaaaaa cgcttgtcaa ctattgattc
     1981 caccgatgag catctgcagc cgcaagtacc acttcctagt ccgggaacac ccgcacctgg
     2041 tggaggtatt ccttcttctg ctttaggaga tttcatgcga ggtatggcag gaacatgggt
     2101 atacgctaat cgaaatgaat ttgacgcaga tgactggttc tgatttatat ctctatctgt
     2161 tatagtcaaa taagtagctg agtcatatgt tatttggcat aatggagacg aggagggata
     2221 gaaaaatgtt agataaaacg ttaccttacg cagaaatctg gatgacaaga ccacttcaac
     2281 aaaatgttcc aatcacgcct ttagcggaag gttttgaatt tcgattttat caaaaagaag
     2341 atgaatctgc ttgggcggag attgagactt ccgttgggga atttcaaacg acagatgaag
     2401 cacttgagta ttttcaacaa aactttgctc cttatcctga agaacttgaa agaaggatgt
     2461 tttttgtaga gacaaaaaaa ggagaaaaag tagcaacctg taccgcttgg cgaaaaaaat
     2521 caagagagca agtgtatccg gtttttcatt ggttagcagt gaaaccagat taccaaggaa
     2581 aagggctcgc aaaagcattg actgccagag tcttgcaaga atttcctacc ctccatacgg
     2641 acggaccaat ctatcttcac acacagacat ggagccatca ggcgattgct ctttataaaa
     2701 aaatgggttt tacttttatt gctgaaaatc tagacggcac acctaatcca gattatgaaa
     2761 aagttatgca ggttttaagt aaattagata aataacgaaa tggtgaaata agtcctcagt
     2821 attgggataa aaaacgaaat agtcattcct catatcttac ttttttgagt taatactatc
     2881 ggataactaa tggcatgcca tacattcaaa aaagaagggg cagtgacaaa agtattgtca
     2941 ctgccccttc tcttgttttt tagcatgttt tatcgtttga tttttttagg aataaaattc
     3001 ttgatgaacg taaatttttg gtaatcgttt cgactataga ggtaaccaaa tacactgaaa
     3061 acaactgctc caataaaatt aacaaataaa tccttcatag tatccatgat tcccacgtct
     3121 aagtaaccat tttggatgat tgttttatct gttttaccat ctgcattttg actttcaatg
     3181 attgtccgag tgatatctgg aacatgatag acagtgtttc cgtctttact taactccaca
     3241 ctattgattt gctggatgat cgtatctttt tgcatatcga attgcagtaa tttatctgct
     3301 gaaaattcca caaactccca cataacacca actgtcatcg aaaaacagaa ggaaacaact
     3361 gctagtaata aaggagtcaa gttcatggtt tttgtatttt tattgagcaa ataaacaagg
     3421 gaaaagccga cacccccagc taaaaatccg ctgaatgcat gtagaaaagt atcccacatt
     3481 gaaaaatagc cataaaaatc acttaactct cctaaaactg ttgaactaaa aataaaagat
     3541 aacaaaatga tttctagcat atttggaatc tgtatcttta atatcttttc cagaaaataa
     3601 gggatttcaa ataaaattaa tgtcagtaat aaaagcattg tatttcccca gtgttggttc
     3661 cagacctgat ccactagcat aataacgacg atgatacgta ataaaatata gattccgttt
     3721 gtgattctac ctgcagtttt tgtactgttc gtaaaaaagg ttttcaaatg attcataaaa
     3781 taactccttc atgtatatcc ttaattatac taagaagcgt gtgtttacca aagctatatg
     3841 acttaaagaa aaacagagtt gatattgtga aaaaaatcac ttaatatagt ataaggagaa
     3901 aagggggata caaatgaaaa aattagttgc tggtttatta acagccgttg cacttcttgc
     3961 tatgagcgca tgcggcgcag atcagaaaaa tacagcgcag acaagttcta gtacgaagga
     4021 atctgccgaa gtatcatcag gcgcttctga acaagtatat acagatccaa aagaaatgaa
     4081 agaatcttat gatgtcgtga ttattggagc tggtggtgca gggatggcag cagctatcga
     4141 agcaaaagat gctgggttga atccagtaat tttggaaaag atgcctgttg ccggaggaaa
     4201 cacatctaaa tcatcaagcg gtatgaatgc ttcagaaaca aaatttcaaa aagaagaagg
     4261 aatcaaagac tcgaatgatg ccttctatga agaaacgcta aaaggtggtg gaggaacgaa
     4321 tgataaagaa atgcttcgat actttgtcga tcactctgct gatgcggtcg attggctaga
     4381 tcaaaacggt atcaaactgg acaacttaac gatcactgga gggatgagtg aaaagaggac
     4441 acatcgtccg tctgatggct cggctattgg tggatactta gtggaggggt tattgaataa
     4501 cgtccatgag cgggaaatcc ctatttttgt caacgcagat gtgacagaca ttaagaaaaa
     4561 tggggaaacg gtcaatgaag tgactgtaca tgttcaagga gaagaaccaa aagaggtcac
     4621 cggaaaagca atcgtagtta ccacaggcgg ttttggtgcc agcaaagaat ttattgaaaa
     4681 atatcgtccc gatttagctg attatattac gacaaatcaa gaaggatcaa ctggagatgg
     4741 tatcaccatg attgaaaaat taggtggaca aaccgttgat atggataaaa tacaaattca
     4801 tccaactgtg cagcaggatg agggggtctt gattggtgag gttgttcgcg gagaaggagc
     4861 aatcttggtc gatcaagagg ggaaaagatt tgtcaatgaa atggatacaa gggataaagt
     4921 atctgcagca attacagcat tgcctgaaaa atcagcttat ttgatttttg accaaggcgt
     4981 gcgtgatcgt gccacagcta ttgaatttta tgaccaaaaa ggatatgtca caactggaaa
     5041 gacaatggaa gaattagcag aaaaaatcga tttaccaaaa gaaacactag caaaaacagt
     5101 tgatggatgg aatacggatg ttgcggagaa aaaagatgct caattcaacc gtgccacagc
     5161 catggaacat gacttatcgt ctccgaatta ttatgcgatc aaaatcgcac caggaatcca
     5221 ttacacgatg ggcggtgtga aaatcaatac gaacactgaa gtattagata aagaaaacca
     5281 gccaattagg gggttatatg ctgctggtga agtcacaggt ggcttacatg gaaacaaccg
     5341 gatcggtgga aattcagttg cggagatcat tatttttggg cgacaagcgg gcatacaagc
     5401 agctcgattt gcttcggaaa atgaatgaaa tagaacgtaa ataaaaagag gttgtgaaat
     5461 cagcgttttg agctaatacc gagggtcagc tgattgaaca ctgtttagtg aagaggttgt
     5521 gaaaaagctg ccctgcatca agtaataaga acagccaagt aaaaacagct tcttatgttt
     5581 ttaacttggt tggacttatt accgcagatg caagcttttg aacaccgttt attcggaaaa
     5641 agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc
     5701 ggaagcagaa gaaattcctt cggaaataag ctgaaattca caaaaatttg aaaagcaatt
     5761 ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct cttttttgat
     5821 cagcatgatt ttattcagtt atcttcaaaa tgatttttcc gatgtttttg tttgcttcca
     5881 tatattcatg cgcttgtttg actgcgctga attggaatgt acggtcaatg attggccgaa
     5941 tcttgccatt ttctagaaaa ggcccagctt tttgcataaa agtttgtgcg agctctgctt
     6001 tatactgatc acttctaggt gtcaataatg taccaagcag ttggacacgt ttcccaatca
     6061 atacaccaag gtctatctca ggcacgatgg tcccacctag cataccaatc aagacccaac
     6121 gtccatcaac ggctatagaa gctaaattct tttcccagta agaagcgccg atgaaatcca
     6181 aaataacatc gactccccga ccttcagtga tttttcgtac ctcttcttga aagtcttgtt
     6241 ttttatagtt gatcaattca tctgcaccaa gttctttaca aaaggcgagt ttttcttctg
     6301 atcctgcagt aacgatgatt ttcgcgtgag aaagctgtct agctaattgg atcgctgctg
     6361 ttcccacacc acttgctcct gcatggatca agacagtttc gccttcttgt aattttccaa
     6421 gccagtaaag tgtttgataa gcagtcaaaa aaacttctga gattccagca gcagaaacat
     6481 agtctagcgt atcagggaga aggattgcac gatcggcagg catcacagca tattcggcat
     6541 aaccacctag attgactaat ccgtatactt ttgtcccagg agtaaaagtg gagatatcac
     6601 ttttattctc aactacctct ccagctactt cgactcccaa aatagggtag ggaggtttca
     6661 aagagactga ttctcttttc ataatatctg ttcgattgac agctgctgta tggactttga
     6721 tcagtaattc gccttgtttt ggtttaggaa caggcacttc aatttgttct aatacatcta
     6781 cagaaccagg atgcttgatt gaaatggcac gcatggatct attcctcctt tgcccattct
     6841 tggaatgctg tattcaactc tttgctacct tcagaaagta ctagagtcgt acgagaaata
     6901 tccgtttctt ccactagagc ggcaagtaca gcagcaactg tagagcgagt gatcgttttt
     6961 gatgccttct cattaggctt agttaattga atggaagtaa cttcttcatc gttagtcaat
     7021 gtgactggtt gaagaatgac aaaatctaag ttagttcgtt tcagccattc atctgcataa
     7081 tgtttagtaa tataataatc tgtcatggac tcaggccatt ttgctggttc atctgcataa
     7141 acagcactga ccatcagata gcgagagaca tgcgcatttt cagctgcgat cactgttttg
     7201 attgcgccat ccaagtctac ttgcagaaga ttctttcctt gagagccggc agcaaaaatc
     7261 aatacatcga tgcctttgaa tgcttcggtc attttttcca cggaccaagt taaatcaaaa
     7321 gagacatacg aaacattctc tttttttact aatgtttggg aagcaacatc tctcacccct
     7381 gcaaaaattt catgggaact tggagctaaa tcttttatca ggtgtcggcc aatttgtccg
     7441 tttgcaccta caacaaaaat tttcatttgg atcatccttt cgacgtcaaa tctttccatt
     7501 caatagtaac accaaaagag aaaaaaatca gagatcggct acgatgacta tcagttagta
     7561 agagaagggt gcttgaagta tcttaacaag acattgcata ctgctgcagt cgcaagacct
     7621 gcgacgattc cttcaggtat accacttgta aaaataaccg ctagaatagc tgaataaaca
     7681 gcatttaaat ttgttccgat gactttggca taatcttgct ggaataaaaa gtagatcata
     7741 ttcatcacta aaatcgtatt ggtcaatgaa ccggaaagtc cagctaagaa taaagaaacg
     7801 gaatctgctt tttgtttcat tagtttgcgc agacctttat aaacgaaata aggaaccacc
     7861 ccaatcaaga tgcgaggaat aaacgcgatc agcaaggctt tccagcttcc atgttctgtt
     7921 ccgatgactg ggataaacgg agaaaagaca aaagacaaag gtgtttggat aactgtgcta
     7981 cggatcatgc tgatcagtcc aaatgtaccg ccaagaaaag cacctagtct tggtcctaaa
     8041 acgatcgaag caatgattac aggaatatgc atggttgttg cattgattgg accgataggg
     8101 ataaaaccta aaggcgtaac agctaataaa atcaaaatag ctaaaaacat cgcagttaat
     8161 gtaaagtttt ttgtattttt cataagtact ccttttttct aagcatttct ttcattaaga
     8221 gtcagcatga cctgttcgat gatcgtctga atatcagcta aggcaccttt tccaaaatct
     8281 ccacaagcta aaagagattc tcttggttca atttcctgat agccgacaga tctcaatgtt
     8341 tccagattac gctgagtgat cgggttttga tacatattcg tgttcatggc aggggcaatc
     8401 aattttggtg ttcccactgg aagcgccatt gcgactgttg aaagaagatc gtctgcaatg
     8461 ccgtttgcta gcttgccgat aatgtttgct gtagcaggcg cgatgagaaa caagtcagct
     8521 tgttttgcta gttcgatatg attgattacc tgcggatttg attcttgcat gacgtctgta
     8581 tggactgcgc gcttcgacag agattgcaag gttaatggcg tgataaaatg tgtgctgctt
     8641 ttagacataa tcacatctac ctgggcacct aatttgacga attgacttgt aagatcagcg
     8701 cttttgtaag cagaaatact tccagtaacg cctagtaaga tctttttcat tttgattcct
     8761 ccagtctaat tttctcagta atcaatgcag caatctcaga tttactttga gcttcttcca
     8821 ctgttccatc tttagataag agatagccgt ggtgtgtctc gccatggatt tccgtcaaat
     8881 catttgcgaa aataaaatca gttttgttat ttatcagact attttttgcg actgccagaa
     8941 gagattcctt tggtacatct actaatagtt tgaaaccaat gatttttgct tttggctgcc
     9001 attcacgtag ataagaaatg atttttggtg ttttcttcaa aacgagcaca agatgctcgg
     9061 tgttagaaga gatctttgaa acagtggtat ctgtctgttc attttccgca aaccaattgt
     9121 ccagttcttc ttgcgttgaa gaagtgggta ggttttttgc cagctgttct tctgaaaaac
     9181 taaaagcagg agtaaaatca ctgactgcca tactgtggat aatcgcatcg tagtgttctt
     9241 ttttcgttag ttcttctaat tgtaaaaata agtccagtgc agattcgatc gtataaatcg
     9301 ttatattgga gtgtcttttc ggtttcagtg cttgtttcgt agtcacgtaa tcgattgtgg
     9361 tatccggatt ggcagctaaa taatcagcta atgcttgccc taatcgtcct gtcgaatgat
     9421 ttgtaatagc acgtacttga tcgatttttt cagtcgttcc tccagctgtg attagaatct
     9481 tcatttatgg tcacctacat ttactagtgt tcttccttgg tgtgttccag caagtagttt
     9541 agatgctgtt tcaggcaatt gatccagagt aatctcttgg acgaccagtt catctgcaat
     9601 ctgcaaatcc gccatctgtt gccataaaga aagacgttga tctattggta cattgacaga
     9661 atcaattcca atcaactgga tgtttcgcag aataaaaggc aagacagtcg cgtttagttt
     9721 gattccccca gcattgccac ataaagctac tgcaccgtta taagagatca atggaagaag
     9781 actgcttagc tgctcgccac ctactgtgtc gatgacatag tcgatttgct gttttcctaa
     9841 agcttttgtt gtctctggca gaaattcatc aggtcgtacg acttgcaaag cacctagact
     9901 ttttagccat gtgacagact cttcttttct ggaaaaggca atgattgact ggaatcctag
     9961 tttatgtaac agggctatcg ctgtactgcc tacaccgcca gaagcaccag taacgacaac
    10021 ttttttatcg gaggtcatac cttgacggat taaagcgttc acacacaaca tagcagtaaa
    10081 ccctgctgta ccaaggatca tcgcttgacg cagcgtcata ttttttggta gaggaactaa
    10141 ccagtctcct ggtacttttt gatattggct ataaccgcct ggatgggtga cgccaagccc
    10201 aaaaccagta gcaagtacaa gatcttcttt tgaaaaacgt ggattgttac tttggacgac
    10261 agttccggat aaatcaatcc ctggagtcat cggatatgtt cgtatcacct gaccagactc
    10321 gctcattgcc aatgcatctt tataattgac atcagaatag gcaattttta ccaagacttc
    10381 attttcagcc aactcagtaa atggcagatc actgattgct gtatggaaaa caggttcctt
    10441 tattacctga aaagatcgaa aagcgttcat tcgtgagaca ctccttttaa aattttcttt
    10501 tatcatacca taaagcctac tcttttattc ttgttcttcc gtaaatttag acaaaaatta
    10561 ggtgaaaaat aaagaatcaa acaactagaa tttattccaa aagataaaga aatattcagc
    10621 aaaaaaaatt ttacaaaggg ttgccttttt caataaattt cgtatactaa tacgagtggt
    10681 agtaaacagg aagtttacta ttagaaaact tcgattcgga ggaaattatg gaaattggtg
    10741 agaagttaag aaatttgcgc atccaaaaga atttgacaca agaagaacta ggcgaacgca
    10801 cagatttgtc aaaagggtat atttcccagt tggaacgaga tttaagttca ccatcaatgg
    10861 aaacattctt ttctattctt gaagtcttag gtgtgactcc agaagaattt tttcatcaag
    10921 aagcagcgaa tctgcaagtg gtttattcaa aagaagatca tacggtttat ttcgatgaag
    10981 aaaacgggta tgaattggaa tggctcgtgg ctgattcgaa tgaaaaagaa atggagcctg
    11041 tcttgctgac ttttgaaggt gcaggagaat ataagacgtt tgaaccttca ttatctgaaa
    11101 cgtttatttt tgtattagaa ggggaattag agttaagctt aggagagacg gtctatgtgg
    11161 caaaagcagg acagtcgatc tattatcaag cgacaaaaca acatcaatta aggaatcatc
    11221 tcaaaaaacg aacaaaagta ttgattgttg caacgcaatc atatttgtaa tatagggggt
    11281 aaaaacgtgg ggaaaccaat catttcattt gatcaagtag tgaaacgcta tgatgatgaa
    11341 acagtattaa aaaaagtaag ttttgagatc gaacaaggaa aattttatac actgcttggt
    11401 ccttccggct gtggtaaaac aacgatccta cgtattatag ctggattcac cgaagctaca
    11461 gaaggggaca tctattttga agggaaacgg ttgaatgatt tgccagctaa taagcgacaa
    11521 gtaaatacag tcttccaaga ttatgcactt tttcctcata tgaatgtttt tgataacgtt
    11581 gcttttggat tgaagatcaa gaaaatgtcc aaatcagata tcgaaaagaa ggtaaaagat
    11641 gctttgcgta tggtccagct tcctggatac gaaaaacggg agattagtga aatgtctggt
    11701 ggtcaaagac agcgtgtagc gattgcacga gcaattgtaa atgaaccgaa agtattgcta
    11761 ttagatgaac cgttatcggc gcttgatttg aaactacgta cagatatgca gtatgaactg
    11821 cgggatctgc aacaacgatt aggaatcacg tttatttttg ttactcatga ccaagaagaa
    11881 gcgttggcaa tgagtgatga gatttttgtc atgaataaag ggaaaatcgt ccaaagtggt
    11941 acacccgtag atatttatga tgagccaatc aatcatttcg ttgctgattt tgttggggag
    12001 agcaatatcg tggacggtgt aatgatcgaa gataatctag ttgagtttgt tggtaagcaa
    12061 tttgaatgtg tcgatggcgg gatgcgtcta aatgaaccag ttgaagttgt tttacgccca
    12121 gaggatttga cgatcacgac accagataaa ggaaaactag tcgtaacggt cgatactcag
    12181 ctgtttcgtg gtgtccatta tgaaatcatc tgttatgatg aacagcaaaa tgaatggatg
    12241 gtccattcaa cgaaaaaagc taaagaagga agcaaagtag gattggcctt tgagccagaa
    12301 gatatccatg tcatgcgttt caacgagtct gaagaagaat tcgatgcacg tcttgacagc
    12361 tacgaagaat aggggggaca agaatgaaaa caatgcgcag gatctattcc gtcccttata
    12421 ttttgtggct cggtttattc gtgatcgcgc ctgtattaat gatcatttat caatcttttt
    12481 ttgatatgaa tgggcaattc acgctgaata attatctatc ttattttacg tcggggacat
    12541 cgctttctat gacgatcaat tctgtatggt atgcattttt gatcacgttt ttcacgctga
    12601 tcatcagtta cccgactgct tattttttaa caaaactgaa gcacaagcaa ttatggctga
    12661 tgctgattat tttgcctaca tgggtgaatc tgctgcttaa agcttacgca tttattggga
    12721 ttttcagtgt gcacggcagc gtgaatcatt tctttgattt tatcgggatc gggccgaaac
    12781 agatattatt cacagacttc agttttctgt tcgtggcaac gtatatcgag attccattta
    12841 tgattatgcc aattttcaat gcattggaag agatgaatcc ttctttgatc agtgctagta
    12901 gagatttagg cgcgaatagc tttgagacct tccgacgagt gatttttccg ttatcattaa
    12961 atggtgtgaa aagtggtgtc caagcagtat ttattccttc tctttcttta ttcatgctga
    13021 ctcgtctgat tggcggaaat cgggtgatca ctttaggaac ggctatcgaa cagcatttct
    13081 tggttacaca aaactggggg atgggttcta caatcggtgt gattttaatc attgctatgt
    13141 tcatcgtgat gctcctgaca ggcgagaaga aaaaaggagg tcgctcataa atgaaaaaat
    13201 ttaaatggtc gtatctttat ttagggatcg tctttttatt cttatatgca ccgatcttct
    13261 atctgatttt ttattccttc aatgaaggag gaacgatgaa cagctttaca ggatttactt
    13321 gggaaaatta tgaagctgtt tttgaagata cacgtttgat cattatcgta ttgaatacgt
    13381 tcatgctggc tttcttatct gcattgatcg ccacgatcat cgggacattt ggggctatgg
    13441 gaatctatta cacgaaaaaa cgacgtgcac ggacagcgtt gttgagcatg aataacatct
    13501 tattagtctc tcctgatgtt attatcggtg ctagtttctt gattttcttt acactactag
    13561 gattcggatt aggttttcag agtgtattgc tttcccatat tgctttcagc attccaatcg
    13621 tcgtcttgat ggtcttgcca aaattgcagg aaatgaacga ttcaatggtc gatgcggcta
    13681 gagaccttgg tgctaataat ttccaagtag tcaaaaatat cattttgcct tatctttctc
    13741 caggaatcat agctggatat tttatggcat ttacctattc tcttgatgat tttgcggtta
    13801 catttttcgt cacaggaaat ggctttacga cgctctcagt agagatctat tctcgtgcaa
    13861 gacaaggaat cagtttagaa atcaatgcgc taagtgcgtt agttttcttg ttctccatga
    13921 tattggtcat tggatactac tttattagta aagaaaaccg tccaaaacgg ctgaagaaaa
    13981 acagaagagt acgcgagggg gtggcacggc tgcgatgaaa aaattacaat ctctgttttt
    14041 aggtattctc atcattattg cggtgctgct gcttggtgtt cgtcaacttg aaaaaacaag
    14101 tggcatgagt ggagcaaagg tacttaccat ctataactgg ggagattata tcgatcctag
    14161 tttgatcacg aaatttgaaa aagaatatgg atacaaagtg aattatgaaa catttgattc
    14221 taatgaagcg atgttcacaa aaatccagca aggtgggaca aactacgaca tcgctatacc
    14281 aagtgaatat atgatccaaa aaatgatcaa agaaaaacta gtacttccat tagatcattc
    14341 gaagatcaaa ggattaaata atattgatcc acgattttta gacttggatt ttgatccaga
    14401 taatcagtat tcgattccat atttttgggg aactttaggg atcgtatata acgataaatt
    14461 ctttgatgca aatcaaatta agcattggga tgatttgtgg aagccggaat taaaagacag
    14521 tttgatgctg attgacggtg cacgagaagt tatggggctt tctttgaata gtttaggcta
    14581 ttctttgaat agtaagaata tggcacagct gacagaagca gcaaataaat tgaatcattt
    14641 aacaccaaat gtcaaagcaa tcgtggcaga tgagatcaaa atgtatatga tcaatgaaga
    14701 agcctccgtg gcagtgacat tttctggcga agctgccgat atgatgtggg aaaatgaaca
    14761 tttacattat gtgatcccac cagaaggatc caatctttgg tttgataata tcgttatgcc
    14821 aaaaaccgtg aaaaataaag aaggtgccta tgatttcatc aactttatgc tagaaccgga
    14881 aaatgcggca caaaatgcag agtatattgg ttattctaca ccaaatgaag aagcaaaagc
    14941 gttattgcca aaagacattt cgtcggacga acaattctat ccatctgatg acacgatctc
    15001 ccatcttgaa gtctacaaag atctaggatc gaaataccta ggcatctata atgacctatt
    15061 cttagaattc aagatgtata ggagataatg gcaaaactca gtaagaatgg ggacttatca
    15121 acgttctaaa gagctaaaaa tcgtcctttt tctatctgag ttttccaatc ttctaccaaa
    15181 agcggatgaa acgccgcttt ttttgtgtta ttttattttt tctaccacgt ttttctacca
    15241 gagaaaagtg gacaaaacca ttgtaaaata gggcccgaga cgggctagta aatctaagat
    15301 tgaaaaagtt acagaaggat aaagtaattg gaaactatgc aaatatactt aacccttctg
    15361 taatctatta ataaaactaa tatatgaatc cagttcaata tttgtagcta tgaaaaaaca
    15421 taaaaatcat attagataaa aactaaattg gtagataaat tattttgtca gatatctgag
    15481 gcaaatattc gactatttgt gtttcaaagt aaaaattgga atacaaatat agaatagaca
    15541 tattgcagcc gatagtttat tatgctttta gacacattaa actggaggaa aaaatgaaaa
    15601 agagcgctaa agatcgagtt tttgatgagc tgatacgact aacagggaat atgtcttctg
    15661 tcactgccga gaaaatttcg aagaatctag gtatctctcg tcagaatgcc agccattatt
    15721 tgacgagatt agtggaagat aaaaaggtcg agaaattacc gggaaagcct gttttgtgga
    15781 agcctttaga tgaatatgcg gttgtagata atacggagca aataaacgaa gcctttcatt
    15841 ctgtagttgg tcatgacgga agtctgagag aggtcattca aaaatgtata gccgctgtca
    15901 aatatccgcc taacggactc agtgtattaa taaatggagc cacgggtgtt ggaaaaagtt
    15961 ttttagccac aaaaattttt gaatacgcta tccatgagca aattattgaa aaagatgcac
    16021 catttgctat cttaaactgt gccgattatg cggacaatcc cgaactgctt tcggcaacac
    16081 tgtttggata caagaagggg gcctttacgg gggctgaaaa ggataccgat ggtttattgg
    16141 caacggccaa caacggctat ctttttctcg atgaggtcca tcgcctatcg aaagaaaatc
    16201 aagaaaagct ctttctattt attgatactg gaaactatcg tccagtcggt gaaaatgtaa
    16261 attggcattc tgctaaggtt cgttttattt tcgccacgac ggaaaaaggt gaaaattatt
    16321 tattagacac ctttgatcgg cgtattcaaa ttagtgttat gttgccaact tttgaagatc
    16381 gccccattcg agaacgatta gagctgattc aattattttt tcaaaatgaa gcggatgttt
    16441 tacaaaaaga tattattgtt tcaagagaag ccttgtcttt aatgttatct catcccttta
    16501 gtgggaatat tggtaagctg aagaatatca ttaaaatcag ttgtgcggat gtgtatagtc
    16561 gaacacaaga agaaccatta acgattggga aaaatgagat cttgattcag ttaaatatgc
    16621 tggaatccga agtagaaagc ttgccgattg ctagtttatt gataaagaaa aatcaaaaga
    16681 taaaaacgga tcgaatcaaa ccgtttgatt atgattcgat tttggaaaaa attactcagc
    16741 tgataaatga aggtaatttc aatgaaaatt tttcttcgat aaagaatgaa gtacagcatt
    16801 tggtgcatca cattgataag gattcttttt tatcaatgag tagaaaattg atgattcaga
    16861 tgtttagaaa ggtctgggta tccgttttag gaaaaacgta cggattgacg acgagtggac
    16921 ctgttgcaga aattattagc agatcctatg tcatttcccc aagctataag acagacttaa
    16981 ccgggataaa tcgtacatta gctgcaaatc tacctcggac gacttactta tgtaatcagt
    17041 tcttggagca tttaccaccg ctctcagaaa aggacgagaa ctttctaaga ctgcttattg
    17101 tcgtgacttt atctgattat gtagatgaat ccatcgagct gaagggcctg ttgcttgctc
    17161 acggagatag tacggctagc agcattcaag cagtagtgaa tcaattatgc ggcaattatg
    17221 tttttgaagc gttggatatg ccagtagaga gtaatgtgtc agagattgtc gaatcgacaa
    17281 ggaatttcgt gaaacggcaa gtgaatacag atagtctagt gctgatcgta gatatgggct
    17341 ctttaaatca aatttacaca cagatcaaga acgatttaaa aggggagtta cttcttctga
    17401 ataatttgac gacttccatt gcacttgata ttggcttgaa gatgacgatg aatgcgccat
    17461 ttaaacagat tgcggaggat gcagcagaca agtattcaat caatgttcaa tactttgaag
    17521 gcttttctca aagtagcaac attatcattt cctgtatgtc gggtttgggg atttcggaca
    17581 aattgaaaga tgtttttcgt catcatttat cggatgaatc catcgaagtt ttcacgaagg
    17641 actacagaga actacgtgaa ttaatcgacc aaaatgatga aacttatttt gacaagacaa
    17701 aattggtcat cacgacttcg gatcttccac gttccttttc aattcctaat attaatgttt
    17761 atgacatctt agacggtgat ggagcagcca atttggagca tattttgagt cctgaaatga
    17821 agccggcaga atttaaccgc ttgattcagg agctagtaaa attcttttcg ttggaaggaa
    17881 ttgcggaccg tttgaacttt ctgaacccaa cgatcgtgat gagtgaagtg gaaacagtca
    17941 tttctaaata tgaaaattac tatcatttca ctttaaatgg ccgtgtaaaa ctaaatctct
    18001 atatgcatac ggcattgatg atggaacgtt tattcttggc tcggacagaa aaatctgaag
    18061 aaccgaatta tgatttgaaa ccagatgaag atgaatttta ttatgtttct agaagtattt
    18121 ttcaatcaat ggagatgaaa tataatttta aagtcaatgc ttatgagctt tcgctgctct
    18181 atgaattatt aggaccgtat attcaaaaat aaagtgtcta aaaaagtgtc taatctgttt
    18241 tttttaggtt agacactttt tttaatgtga attaacgtga ttaaaccaat gtttttaaaa
    18301 gttggcacag gaattgctta tataaaagtg aacagaaaga aaggaattaa ccatatgaag
    18361 aaaattctaa tagcgactca cggtcactta gcttcaggct ttcttagcag tattcaatta
    18421 ctgacgggga aggttcaaga gattacggtg attaatgctt atgtggatga gtgtgatttt
    18481 gaacaggagt tgaatgtatt tgtaaaccag gtgaacgagc aggatcagat ttttgttttt
    18541 accgatttat ttggcggaag tgtcaatcag aagattacca aaaccttttt ggagaaagag
    18601 attgctgtaa ctattttgtc tggctttaat ctgccaattc tgctcgaaat agtattggca
    18661 accaaggaat taacaaagga ggatattcag gaactggtaa ataaatgcca acaggaatta
    18721 aagatgacca ttcttgatga ggtacatgta gtaaatgaag aggaagattt tttttaggag
    18781 gaagaaaaat gattaaatca gtgcgaattg atgaacgatt aattcatgga caagtagcga
    18841 tgacttggac aaagagtcta aatttaaccg ggttagtagt agcaagcgat gaggcggcta
    18901 ccaacgatat tcaaaagatg acattgaaga tggctgcacc atcgaatgtc aaagtcatta
    18961 ttaaaacagt tgatgacgcg attcatttgt taaaagatcc gcgggcgaag gacatgcgct
    19021 tgatggtttt agtccctaat gtcaaagatg cggtaaaagt tgcgaaagct ttcccaacgg
    19081 aaatcgaatt aatgaacgtg gggaatgctg ggaaaatgac accgccatcg gaagataaga
    19141 aaaccttatc aaaggaagtg atgttaacga cgtcagaaat tcaagactta aaagaattag
    19201 ttgaacttta tccagatacc gtttttcagc ctacaccggc gatggaaaaa cgttcagcta
    19261 tctctatttt gagtgatttt tagaaaaagg aaggagaaaa attatgtatg atgcatttgt
    19321 agtcgctttg gccgttttta ttggagttgc tggacatgaa atgttcggga tgtccatgct
    19381 gagtcgtccg attgttgttg ctccgttagc aggagcgttg atgggggatt tgcagacggg
    19441 gttgattgtc ggggcgtcac tagaagccat ctttatgggt gtcgtcaata tcggaatctc
    19501 tagtacggcg gagccttctt tggctgctgg gctggctaca gcgttcgcaa tcaaaatggg
    19561 aggaaacgtg gatgcgatta ttcccattgt ctttccacta gcagtattag gattacagtt
    19621 aatgaatatg attttttctt ttgtatgtgg accgatggct gctaaatttt tcaaatttgc
    19681 aaaatctggt gatcaaaaag gaatcatcaa tctgcacttc tttatgtggt ttgtccacta
    19741 tgcgctttat gctcttattc cattctttgc cgttttattt ggagcagatg ttgtcaaaag
    19801 cgtcttggat aatattccag aggtcatcat gaacggatta acagtcgctg gaaatctgct
    19861 gccggcagtt gggatggcga tgctgttacg gatgctttgg agtaaaaata ttgctgtgtg
    19921 gtttttcttt ggggccgttg ttatggcgta tctcgagtta ccattgattg caattgccgc
    19981 agttggaacg attattgcaa ttgttatagc ccaaagagat ctacaactaa aaaatatatc
    20041 tgttcatgca gttcaaagcg atgctgctgt aaatgcaacg cttgaccaag aagaggagga
    20101 tttctttcaa tgaaattagc tgatggaatt tctaaagatg agaaaaaatt ggttcggaag
    20161 atgttttggc gctcgatgac tatgtatgct tcggtgaatc cggtgacgat gggcggcggt
    20221 ggtttcgcct attctatgat gcccttcatt aatcatttct acaaaagtga agaagatcga
    20281 gctgcggcgc tggaacgtca tacacagtat ttttcgacga ccattccttg cgcgtccttt
    20341 gtcatgggga ttgcggcatc gatggagaag gaaaattctg aaaaagctgg ttttgacgtg
    20401 gaaagtatca acgcgatcaa aacgagtttg atgggaccat tggctggaat tggcgattca
    20461 ttgttctggg gagtttggcg tgtcgttacc gcgggactag cgatcaactt agccaatgcc
    20521 ggaaatattt tggcaccaat tatcttttta gttatgttca atatacctaa ttacttgatg
    20581 cgatactatg gcggcgtttt aggctattca ttaggctcta aatatattga aaagctgtat
    20641 gcgaacgggt taattgaaat tctgacaaaa gctgctagta tcttgggtct gatcatggta
    20701 ggtgcaatga cgatcagtat ggtcaaattc aataccgttt tgagcttttc aatgaagggc
    20761 gaagaactaa tgaatgtcca agaaatcctc gatagtattt ttaaaggaat tgtaccgtta
    20821 ttggtaacat tgagctgttt caaattacta gataaaaaag tcggcgtcat caaaattatt
    20881 tttggaatgg tcgtcttggg aattttattg tcattacttg gaatcgcata gtaggaagct
    20941 gcagctacta ggctgcagtt tttttagcaa ggagggaaaa gatgactatt aatgaagtaa
    21001 tttattcacc caaacaccca ttttttaatg ctgagttaaa cgacggaaat gtgactactt
    21061 caaacgaata cagctactat cggaatattc ctgatgtaaa gggattgacc ttcgatgtaa
    21121 gtaatcaaaa gacattagca aaccttgatg tttgcgggac gattcaaacg ttgacctttt
    21181 atcgagaaaa tttactaact gaggaaaaac caggtgtttg ggtcaataaa cagctctctc
    21241 aaaccaattc gttatcctta aaggttgaag taaacgggat tgtctaccat ttgtcagaat
    21301 cggatcatcg tattgaagtc gatgtgattc aagactgttt gcctagatat attcatcatt
    21361 attcgacgtt taaggtcatt gtagtatcct ttgctcccat actggctaat aagcgtttaa
    21421 gtatgcttgt tcaacaggtt tacattgtga atgaaacaca cgaaagcctt caagtttcag
    21481 tgaaagatgt gccttcgtat caagagaagt attcggatca gcaaaatgtg ttgatttctc
    21541 aaaaaggaaa taaggacacg atcgcacaac aggaagtggc aagcttcgcc attgcttttg
    21601 tggacccaaa tgcttttgaa gaagtaatga cttttcagga atctgatatc gaaaaatggc
    21661 tgaaggaaac attgaactat tttgctcagc tatttgggca gctgtcaatg ccaaacgata
    21721 gagttgtcca tctctatcgt cgtgcacttt atcaaagctt ttctagtttc ggtatgaatc
    21781 gacagggaca ggtcgtcggc agcaattggg gcagctatcc tgctactaat cgaatttgga
    21841 ataaggatat gtattacgca tcattgccat tcaccatgtt tgaaccggag ttatgtcaaa
    21901 aaacggttct atggtttgat caatatggcg ttaagtttcc tggttcaaaa tttacaggag
    21961 gtatcaatca ttctctgagt aattcgttat ccagtgcgtt actggctagt ctttattttg
    22021 aacatactgg ggatacaaaa ttctttgagc ggtgtccgca ggttctactg aatgcttcaa
    22081 gaattattga ggacatatta gctcaacgtc ggtcagggga accaatgctt tttccatctg
    22141 tttggttatc agacgccttt gcacttggaa agtatcatac cggcagcaat ctttgtcttt
    22201 ggaaggcctg tattggactt gcagaaattt ttgaagccct agaacaactg agtcttagca
    22261 agcgatacaa aaacattgcc tgtaaactaa aggaatcaat ttgtaaacaa atgactatcg
    22321 atggtccttt tggtgagcaa tttttggagg gaatcggtga tgaggagaaa acaacctatt
    22381 cagtgaagca ctatcaaaaa ccgattcttg agcaagggtt aatcttttta agtgatgtga
    22441 ttgtggatgg aaaaattaat ttattgatgc atgatggaga agaatcagac actacgttga
    22501 tgccttttta tcaattttta gataataaag atcatttata tcagaacacc atggcctttt
    22561 ctgctagttc tttcaatcca acctatagcg aggaaatcaa aggcatcact tggggattag
    22621 aatccggcgc cacttttcct ggctttatca ctgttttaat gagcgagctg cacaaccctc
    22681 aagctttcgt aacccgatta gaagaactaa tttgtttggc agatttagac ggttcgtggt
    22741 ggtggtggcc gtatcgctta gaggctcaac aaggagaagt cgtgcgagac tttggctgcg
    22801 gcaaatgcgg ctgggcatcg ggtctttttg tcagcctaat gatcagtcaa tatttcggat
    22861 tgaaattcaa aaaaggagta ttgcaaattg atcctgttga taatttaacg ttttcttgga
    22921 agaatttgaa gttcggtcaa gccttcattt cgattgaatg tacgcaatcc gagttgagta
    22981 tttcaaattt gtcagaaaag ccattgaaaa taagtgatac gaaaaaaatt cttcacgtag
    23041 aaaagggaaa aacgattcac attcaaagga gaaaaagatg agtatactaa aaaatattac
    23101 ccaatttaaa aaaatccaga gtcgagcaat cactcccgaa aatccaacag gcgagaaagg
    23161 taaagctgcg atgttgccaa gcgagctagg accaagccgc aaaggtcgtg gcgcaattcc
    23221 gctgacttct ggtgaagaaa ctgtgattgc ggatattact ggaacgggaa taattcgtca
    23281 tatgtggatg acgattcgtg atcgaacaga atttggcagt tttgttttac gtgatttaat
    23341 cttaagaatt tattgggatg ggtcggatag ccctgctgtt gaaagtcctt taggggattt
    23401 cttttgtaat gggtttggag agcgttgcga ggtgaactcg ttgccgatag tggttaatcc
    23461 tacagggggc tttaattcct atttcgaaat gcctttccaa acatccgcta aaattacgat
    23521 cgagaattta catccgaagg atatgtcctc atttttttat acgataaatt acgctttggt
    23581 ggacgaattg gaagaaaata gcctatattt tcacgcaaat tggcatcggg aacgcattac
    23641 caaattacag gaggattata agttaattga tcgattaaag ggtcaaggct attacgtggg
    23701 tacttacctt gcgcttacct gcctagaacg ttattggtgg ggcgaaggcg agtttaaatt
    23761 ctacattgat ggggatagtg agtatccgac cgtaacctca acaggttcag aagattattt
    23821 tggcggggcg tgggcctttc atgagtacga tgagttcgga cgtccacatg cgaaaaacta
    23881 ttcaacagcc tttttagggt atccttacca atcaaataga gatgccacaa gagatcgttt
    23941 tgaaacggga aaattgaatg ccgttcatgc ctttggtgac gacgcaatgc cacgacatgg
    24001 tctttatcgt tggcatcttc aagaccccat ctgttttacc gaagatttat cggtcacttt
    24061 acaacaaatc ggcaacgatg atgttcgctt atttgagcgg caagacgatg ttgctagtgt
    24121 cgcttactgg tattcaacag aagcttcagg aaatactaaa cgtcatttca ctgatcgaga
    24181 acgcttgccg cgttaatgaa gtgtttttca catattcgaa gggaggaacc tatgatgata
    24241 tatggggcaa ttgaagctgg agggactaaa tttgtctgtg cagtcggtac tgaggaatta
    24301 acgattttgg aaagagtcag ttttcccaca acaactccag ttgaaacaat gaagcaggtc
    24361 attgattttt ttaaaccttt taaggaacaa ttggcaggca tcggggtcgg ctgctttggt
    24421 ccaattgata ttcaatgcaa atcaacgagt ttcggtcata tcacatcaac accaaaactt
    24481 gcttggcaaa atttcaattt tgtaggaacg ctaaagcaat atttcaatat tccgattgaa
    24541 tggacaacag atgtcaatgc ggcttgctat ggtgaatatg ttgctggttc tggcaaaggg
    24601 ttagcaggtg ttgcatactt cactgtggga acaggtatcg gaggtggtgc cttgttcaat
    24661 gggactttcg tggaagggtt cagtcatccg gaaatggggc atatgttgat caagcgacat
    24721 ccaaaggaca atttttcagg aaactgtccc ttccaccaag attgtttaga ggggatggca
    24781 gcaggaccag cgattgaaaa acggttgggt gtaaaaggcc agaatttatt ggctgacgat
    24841 tcgttttggc agattgaagc cttttacctt gcccaatgtg catacaatac aacactgatg
    24901 ttttcgccag atagaattat ttttggcggt ggtgtaatga aacaagaaca catgaagaaa
    24961 aaagttcagg ataaatttgt tgagcttata aatggatatg ttgaaatacc accaattgat
    25021 agctacatta ttacgcccga attaggtgat aatgccggaa taatcggcgg attagcattg
    25081 gccagaaaag cggtaagaaa taagcaacca taattaatga atgtttcatt gatactcatg
    25141 tcaaaagtat ttaaccgagt aatcaaatga tcaaatgaag ttggataaag cgaaaatgaa
    25201 ttcaaataaa aaggctctaa gtcaaatcgt gttgttttca ttaaatcact gaaaggaaat
    25261 gcttctgcgt ttcctttttt ctttttgttg tgcgctgtat accttgagga tattcactgg
    25321 tggcgtacac ttaaatagta atatattgtg ttactttatg tctgtggtaa tagttatagt
    25381 tgcttaccaa tgtatgttca tttttcgaaa tgttgacttc ataatccttg gcttaatgtt
    25441 tgaatttttt tggtgataga ttttttcagc cgtataaaat aaatcgtaat t
//
LOCUS       DADVXB010000027        24435 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.027, whole genome shotgun sequence.
ACCESSION   DADVXB010000027 DADVXB010000000
VERSION     DADVXB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.027"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..840)
                     /locus_tag="KB902_000875"
     CDS             complement(<1..840)
                     /locus_tag="KB902_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6807718.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMD"
     gene            complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="KB902_000876"
     CDS             complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="KB902_000876"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBB6807719.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3341..3520)
                     /locus_tag="KB902_000877"
     CDS             complement(3341..3520)
                     /locus_tag="KB902_000877"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBB6807720.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="KB902_000878"
     CDS             complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="KB902_000878"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6807721.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5668..7947
                     /locus_tag="KB902_000879"
     CDS             5668..7947
                     /locus_tag="KB902_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6807722.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8040..8687)
                     /locus_tag="KB902_000880"
     CDS             complement(8040..8687)
                     /locus_tag="KB902_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807723.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8866..9585)
                     /locus_tag="KB902_000881"
     CDS             complement(8866..9585)
                     /locus_tag="KB902_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807724.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9716..10867)
                     /locus_tag="KB902_000882"
     CDS             complement(9716..10867)
                     /locus_tag="KB902_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBB6807725.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11084..11824)
                     /locus_tag="KB902_000883"
     CDS             complement(11084..11824)
                     /locus_tag="KB902_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6807726.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="KB902_000884"
     CDS             complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="KB902_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBB6807727.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="KB902_000885"
     CDS             complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="KB902_000885"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBB6807728.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12785..13435)
                     /locus_tag="KB902_000886"
     CDS             complement(12785..13435)
                     /locus_tag="KB902_000886"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBB6807729.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="KB902_000887"
     CDS             complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="KB902_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBB6807730.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="KB902_000888"
     CDS             complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="KB902_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBB6807731.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14878..15405)
                     /locus_tag="KB902_000889"
     CDS             complement(14878..15405)
                     /locus_tag="KB902_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBB6807732.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15585..16370)
                     /locus_tag="KB902_000890"
     CDS             complement(15585..16370)
                     /locus_tag="KB902_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBB6807733.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16363..17232)
                     /locus_tag="KB902_000891"
     CDS             complement(16363..17232)
                     /locus_tag="KB902_000891"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBB6807734.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17233..18612)
                     /locus_tag="KB902_000892"
     CDS             complement(17233..18612)
                     /locus_tag="KB902_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBB6807735.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="KB902_000893"
     CDS             complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="KB902_000893"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6807736.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19064..19540)
                     /gene="accB"
                     /locus_tag="KB902_000894"
     CDS             complement(19064..19540)
                     /gene="accB"
                     /locus_tag="KB902_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBB6807737.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="KB902_000895"
     CDS             complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="KB902_000895"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBB6807738.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALAILLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="KB902_000896"
     CDS             complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="KB902_000896"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBB6807739.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="KB902_000897"
     CDS             complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="KB902_000897"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6807740.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22570..22794)
                     /locus_tag="KB902_000898"
     CDS             complement(22570..22794)
                     /locus_tag="KB902_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6807741.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22847..23809)
                     /locus_tag="KB902_000899"
     CDS             complement(22847..23809)
                     /locus_tag="KB902_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBB6807742.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23819..24259)
                     /locus_tag="KB902_000900"
     CDS             complement(23819..24259)
                     /locus_tag="KB902_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6807743.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6691 a         5437 c         4246 g         8061 t
ORIGIN      
        1 atccataaaa tattcttgga ttgcttctcg tgtttttttc actttttcgc taagcttttc
       61 gtttttagcc atatagaaat aaaaaatgat atcgatcgta gcaaattggg ccaaaagtga
      121 attagttgcc gcacttcgat tcgtgatttc ttttggtcta gatgtttgta cgagtacatc
      181 ggctatcttg ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat
      241 gcttttcgcc agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag
      301 ccaaagcact ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt
      361 ttcaaaaatg attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa
      421 agaagaggcg ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac
      481 tttttggatc gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt
      541 gttaccaagt ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc
      601 ttcatcgatt ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg
      661 aaaaccgatt tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc
      721 taattcatta gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa
      781 ctttttttct gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat
      841 aagttcctcc acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca
      901 cggtcgtata ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat
      961 caatcccaca gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc
     1021 ggattgcttt ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt
     1081 aatttttgac ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt
     1141 ctttacttcc ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa
     1201 ctaattggta agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat
     1261 tacgatcatc aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag
     1321 cataatcgcc atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc
     1381 atgttggaaa agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag
     1441 aaacaattcc gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat
     1501 atgtcaaatc aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt
     1561 ctgtaccaag agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc
     1621 cttctgcttc aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg
     1681 ctttttccca cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc
     1741 tcaagcggaa acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa
     1801 gcgtacgttt aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca
     1861 acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca
     1921 tcattcctaa ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt
     1981 agaccatcat gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca
     2041 tatccattgg cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca
     2101 actcaacatc tcccattatt ggtgtatata catgttggta acctagacta acttctttgt
     2161 ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca
     2221 aaccagaacc tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat
     2281 ggtctctttc ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa
     2341 aaaaggctgt cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag
     2401 cacctgccac tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc
     2461 cacgacacaa atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca
     2521 attcactaat cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt
     2581 ttgaaagaac acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt
     2641 cgattgccgg caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa
     2701 accctgaatc gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg
     2761 cttgggccat caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg
     2821 gtgtgatgat ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc
     2881 cgttcacttt accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg
     2941 ccaatgttgt tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta
     3001 tcataatagt ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa
     3061 aaaatcctag catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat
     3121 gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa
     3181 gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc
     3241 tctcttatcg aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt
     3301 taaccactaa taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat
     3361 ttacaccgta tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg
     3421 cctgcgtgtt tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg
     3481 gactgcgacc ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg
     3541 atcgttcttt tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga
     3601 aaaatggctg gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact
     3661 tcttgcaaaa cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa
     3721 aaaatacaaa taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt
     3781 gaaatcacta ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca
     3841 ctttcactag cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca
     3901 agtgctggtg cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg
     3961 atactttcta aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat
     4021 tggacttttt ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa
     4081 tttttcacat caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga
     4141 tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg
     4201 gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta
     4261 ttgactactg cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt
     4321 tggctgtttt tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct
     4381 gcactagctg catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc
     4441 tctacttcca atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta
     4501 cgtgcgagct tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg
     4561 ctcattcctg caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact
     4621 accagtacct cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc
     4681 aaataagcaa tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca
     4741 ggcttttctt ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca
     4801 cgtttttcag cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga
     4861 tctccaggtt tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa
     4921 gattctcctt tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac
     4981 tggtcatcaa tatttatttc atcgattact atatcctgca attttccttc tttgaatcga
     5041 tgggcaattc ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc
     5101 gcgtaatcct ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag
     5161 tattctttga cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat
     5221 cttcctgaac gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca
     5281 gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa
     5341 gctatcccac caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct
     5401 cctcttttat gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa
     5461 gcatagtcct tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact
     5521 atcagcgttt ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt
     5581 tcgattcatc agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt
     5641 atttacggcg gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg
     5701 gatgaaacga tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa
     5761 ttgactcagg aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt
     5821 tccaatgaag ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt
     5881 ttgaaatacc atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa
     5941 gatagtcctt attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat
     6001 ctaggtatcg cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca
     6061 ccaattgcca atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca
     6121 gatagaatag atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt
     6181 ttatctatgg tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat
     6241 gaatcatcaa gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca
     6301 atcattcggg acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag
     6361 acatccgctt tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag
     6421 gctgaaaacg ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta
     6481 ttgccttcat taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag
     6541 ctgctgccag agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg
     6601 gaaaaagatc cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc
     6661 tatatccaag gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt
     6721 acgatcctat caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct
     6781 ttacatcata gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa
     6841 aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta
     6901 tacgcaacag atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa
     6961 ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat
     7021 caatttgtca atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt
     7081 ctaacacgac ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca
     7141 cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc
     7201 cgaacatatc cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag
     7261 gatttcgcac catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact
     7321 ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa
     7381 gaccttttcg tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca
     7441 aaagaaatca ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca
     7501 gcaagaaaag gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat
     7561 tggttagcag ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc
     7621 atagctaaaa cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa
     7681 caacaagtcc agctgatttt aaatgagagt gactttatga agcgttccat tattttactt
     7741 ccagcctttt tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca
     7801 gaacattttt cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg
     7861 catgaattga ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt
     7921 tcatcttatg agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca
     7981 gttgtctttt tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt
     8041 tattctatat ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc
     8101 attttcagtt cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca
     8161 atcccgccat tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat
     8221 tggaaattgc tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg
     8281 tatgcactat cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga
     8341 attttttcag gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga
     8401 tactcttctt caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga
     8461 taattttgtc tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc
     8521 agataccctg taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat
     8581 ttttgcgcta attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa
     8641 ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc
     8701 catcttccac atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt
     8761 tgaattagaa aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc
     8821 ttgcttttcg aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc
     8881 cacattatgg aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc
     8941 aaatgtttct tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc
     9001 agcgattgaa aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc
     9061 cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat
     9121 gtctttttcc attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat
     9181 tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt
     9241 cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac
     9301 aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc
     9361 tcctgcacct tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt
     9421 tttagcgcga tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga
     9481 ttttgctgcc gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc
     9541 tttagcagtt ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt
     9601 tctgatttga tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga
     9661 ttctgtgaag ctttttttct ttcttccttc attcttctca tttttagtca attatctata
     9721 ctcggattgg gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt
     9781 gatcacttct aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa
     9841 tagaaatctc ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc
     9901 gaagataatt tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat
     9961 aacaagataa tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa
    10021 aatcctcaaa actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg
    10081 tcatctgata gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat
    10141 acggccaata agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag
    10201 gcggcacaag tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac
    10261 tggctatcct ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg
    10321 gatgtaattc catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga
    10381 tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag
    10441 tcattttttg cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc
    10501 tatcttgatt ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt
    10561 ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag
    10621 caaaatagtc agctgactga accgcccatt cgacgggaag ctccactact aaatccacac
    10681 cattttgtaa agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt
    10741 gcaaaaaatt cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca
    10801 tttccacatg atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc
    10861 ttttcatgcg catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa
    10921 aggcaaaaat cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc
    10981 tgcgacgaaa agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt
    11041 tgaagattta ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta
    11101 caaagaacca gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt
    11161 cgactttcga aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac
    11221 gctcttgatg tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga
    11281 aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa
    11341 aagcaaaatt atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat
    11401 aggtggagtg tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat
    11461 caaacacttg ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg
    11521 taattgcctg atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga
    11581 tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt
    11641 ctaaccctgt cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc
    11701 atgccagttc caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc
    11761 attgctgata aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag
    11821 ccatatgtta atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt
    11881 ccagattata gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat
    11941 cgatcaatac ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt
    12001 cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg
    12061 aacagatcat gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt
    12121 cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta
    12181 tgatgatttc ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc
    12241 gattgttttt ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt
    12301 ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc
    12361 aggaaaatct cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact
    12421 catcttagca gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat
    12481 tcctaattcc cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata
    12541 attcaataac tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg
    12601 tcgttctttt gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc
    12661 gtattttttg gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg
    12721 ttcgctcatt ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc
    12781 attactatag tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg
    12841 gaacaaggta gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga
    12901 tgtcgatctc aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg
    12961 gtcgacgtat acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg
    13021 gcaaatattc taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt
    13081 gcgtcaattc cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg
    13141 tttcaatctg caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt
    13201 ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata
    13261 cgcggtcaag acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa
    13321 cgggattgaa tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca
    13381 tttcttcagg aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca
    13441 ctccttatat tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt
    13501 tgtataatac aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta
    13561 atacttgagc tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca
    13621 gttctctttt ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt
    13681 ttccgatttg aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt
    13741 ttcctcttaa actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat
    13801 ctacaccctt tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta
    13861 gaccggcaaa aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg
    13921 gaaatgcctc gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat
    13981 aaaattcgtc tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag
    14041 caataaatga agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa
    14101 gtgtttgccc ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga
    14161 tccgcaaatc ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg
    14221 tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg
    14281 gaaactgcga agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga
    14341 taagcgtcga ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt
    14401 attcttcgat tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata
    14461 atacatctac tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt
    14521 tagttttttt caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat
    14581 tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca
    14641 ccacattgac gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt
    14701 catccgtcaa tgagacatct tggatctcat tataatggcg taatctgaaa caacgctgac
    14761 aatagacttc cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt
    14821 caccgggttt gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca
    14881 ttcgattcca cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct
    14941 tttttcccaa aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac
    15001 aaggatgcta cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc
    15061 taccattact atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct
    15121 tgctaaaggt ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc
    15181 gacacgtttt gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc
    15241 taaaatccaa gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt
    15301 gtctaaatcg gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg
    15361 atagatggct tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct
    15421 gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca
    15481 aaaaaaacta cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc
    15541 aaaaataaag attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac
    15601 ctcttgtatc gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt
    15661 tcaatcaacg cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg
    15721 aacgtttcag gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt
    15781 ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat
    15841 ccttctggag aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa
    15901 cctagagcaa gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc
    15961 tttaaatcag acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct
    16021 gctcctacac cgcaatatgc acctgctgta ttgatcaagg taatcaccgg tctattgaac
    16081 ttttccgctt gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca
    16141 aaatttctgc ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc
    16201 ggtttgccat ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga
    16261 tcaccatggc attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat
    16321 cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca
    16381 tcctttctgt gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg
    16441 aacaatctga tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg
    16501 aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg
    16561 gggttctgct agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt
    16621 cgggtccgtt aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc
    16681 agagattttt gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga
    16741 agctgtgaac aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat
    16801 cttttctccg acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat
    16861 aatgaaggga atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt
    16921 tttatcttgc atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt
    16981 tacaagatcc gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg
    17041 ccatgcaccg attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc
    17101 tttcgtataa aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga
    17161 tggcgagtta gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt
    17221 aaacagagcc atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc
    17281 ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc
    17341 catctgaaat tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg
    17401 catcttcatt aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga
    17461 atcataatat ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat
    17521 cccacctgct ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc
    17581 aggattttct gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg
    17641 acacacattc aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc
    17701 tgtgaccatt tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata
    17761 aaaatcgcct tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc
    17821 tttagctgct cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac
    17881 agaaggagat tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc
    17941 taaatgaatg acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg
    18001 ataaatgatt ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg
    18061 agctgaagaa aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc
    18121 gccaccacct gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa
    18181 tgcttcttct actgtagata atacaccagt acttcctgga atgactggga catttgcttc
    18241 ttgcatcaat tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg
    18301 accaataaat gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa
    18361 aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc
    18421 ctgaacattc agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc
    18481 taactgtgta tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc
    18541 tagttcgcgg catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac
    18601 tttagaaaac atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt
    18661 taccgtctac tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct
    18721 caacttcaag gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca
    18781 atccgccgaa ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc
    18841 ctgcttgagc cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat
    18901 gtccttgaaa aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt
    18961 caaccatttc ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt
    19021 ttatttcttg tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc
    19081 taaagagtgg ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca
    19141 ctccgtcggc ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa
    19201 cttctccttt ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt
    19261 gcagataaac gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt
    19321 ctttttcttt cattatttct ggagcagttg ttgcttgttc agatatgaca ttgactggct
    19381 ccgaaactgg caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt
    19441 tattcatata caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat
    19501 caaattgact gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt
    19561 catgcacaga accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa
    19621 acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc
    19681 tacattgatc gtaggtggga taaattgatg ttctaatgcc agcaaaattg ccaaggcttc
    19741 gatcccgccg gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt
    19801 atctctgaaa ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc
    19861 tggtgtactt gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc
    19921 ttccatcgca agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat
    19981 atggtaagcg tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg
    20041 agcttgtgca tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa
    20101 accattccga ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag
    20161 tgctgttaaa gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc
    20221 agcaagaatg acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt
    20281 cgttccgcta gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa
    20341 agcaatattt ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg
    20401 ttttgcacct ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat
    20461 cccagatccg atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct
    20521 catctccatt gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt
    20581 gctatctttt ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt
    20641 aatccctgtt tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt
    20701 taagctattc aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt
    20761 aattaccact cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc
    20821 atcgacattg atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg
    20881 tgcaatatct tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt
    20941 gactttgtct gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt
    21001 acatgtaatg cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc
    21061 agctttacta gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga
    21121 gagattaatg atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat
    21181 attgaaggtt ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg
    21241 catcacaagt ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag
    21301 cttttcttct gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga
    21361 aactcctacg cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc
    21421 tccgcgacca ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt
    21481 gccgattcct cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt
    21541 cctccttata gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact
    21601 ggtattgttt tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg
    21661 atgacttgtt cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt
    21721 tgcatgactt gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt
    21781 gtgttgctta tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc
    21841 agtttttttg ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg
    21901 atcattcttt tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct
    21961 tcgccaccaa tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac
    22021 ttgctagctt catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc
    22081 attttcccgc ttccagctgg ggtagcttct gtcatataag cgcctctttt tgctactaac
    22141 gcaactgctt cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa
    22201 ctcagtccta aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg
    22261 atgctgactg ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct
    22321 gtaaagcaaa gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc
    22381 tttacaacgg cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca
    22441 ctaaataaga atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc
    22501 ttcctattca aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa
    22561 ttttaatgat tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat
    22621 tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa
    22681 taaatccaag ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc
    22741 agtttctttt cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat
    22801 atattcctcc gatattgttt gctttttatt tttataattt aacagtctac aactccatga
    22861 gaatacttcc ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc
    22921 ctaaggtgat ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag
    22981 atgtattccc atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc
    23041 gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt
    23101 tgtctttcat gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat
    23161 ctctgccagt catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt
    23221 tattttgctg gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt
    23281 ctttcagcaa ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa
    23341 acaacacagc agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa
    23401 tcaccagtcc cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa
    23461 caaatcctga gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc
    23521 cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa
    23581 taaaatccaa atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa
    23641 tgcataaatc agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg
    23701 acgaaatcca ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct
    23761 tttcaggaag gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc
    23821 acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt
    23881 cctccgtagc cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga
    23941 cccgaaatag taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt
    24001 cactgcggat acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg
    24061 tcccaacagt aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc
    24121 cgattgcctc gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca
    24181 gctcagactc ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg
    24241 tttttaaatc tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg
    24301 atgttcaaac tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact
    24361 atatgagctt tttttaagat tttactcatt taaaacaact gataaatcag catttataat
    24421 ttcttttatt agaaa
//
LOCUS       DADVXB010000028        24132 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.028, whole genome shotgun sequence.
ACCESSION   DADVXB010000028 DADVXB010000000
VERSION     DADVXB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.028"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="KB902_000901"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="KB902_000901"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBB6807744.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2477)
                     /gene="purK"
                     /locus_tag="KB902_000902"
     CDS             complement(1353..2477)
                     /gene="purK"
                     /locus_tag="KB902_000902"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBB6807745.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="KB902_000903"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="KB902_000903"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBB6807746.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="KB902_000904"
     CDS             complement(3374..4681)
                     /locus_tag="KB902_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBB6807747.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="KB902_000905"
     CDS             complement(4684..5265)
                     /locus_tag="KB902_000905"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBB6807748.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="KB902_000906"
     CDS             complement(5837..7129)
                     /locus_tag="KB902_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6807749.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="KB902_000907"
     CDS             complement(7126..7749)
                     /locus_tag="KB902_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807750.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="KB902_000908"
     CDS             complement(7752..8588)
                     /locus_tag="KB902_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6807751.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="KB902_000909"
     CDS             complement(8605..9492)
                     /locus_tag="KB902_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807752.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFFFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="KB902_000910"
     CDS             complement(9508..10791)
                     /locus_tag="KB902_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6807753.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="KB902_000911"
     CDS             complement(11474..12157)
                     /locus_tag="KB902_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6807754.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="KB902_000912"
     CDS             complement(12175..12792)
                     /locus_tag="KB902_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6807755.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="KB902_000913"
     CDS             complement(12802..13626)
                     /locus_tag="KB902_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBB6807756.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="KB902_000914"
     CDS             complement(13619..14179)
                     /locus_tag="KB902_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807757.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="KB902_000915"
     CDS             14353..15309
                     /locus_tag="KB902_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6807758.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="KB902_000916"
     CDS             complement(15614..16570)
                     /locus_tag="KB902_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBB6807759.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="KB902_000917"
     CDS             16674..17276
                     /locus_tag="KB902_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6807760.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="KB902_000918"
     CDS             complement(17364..18863)
                     /locus_tag="KB902_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBB6807761.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="KB902_000919"
     CDS             complement(18879..19403)
                     /locus_tag="KB902_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBB6807762.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="KB902_000920"
     CDS             19701..20450
                     /locus_tag="KB902_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6807763.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="KB902_000921"
     CDS             20441..21226
                     /locus_tag="KB902_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBB6807764.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="KB902_000922"
     CDS             21195..21911
                     /locus_tag="KB902_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6807765.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23047)
                     /locus_tag="KB902_000923"
     CDS             complement(22013..23047)
                     /locus_tag="KB902_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBB6807766.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEFFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23051..24109)
                     /locus_tag="KB902_000924"
     CDS             complement(23051..24109)
                     /locus_tag="KB902_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBB6807767.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7142 a         5209 c         4212 g         7569 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaaaaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaaactc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt ca
//
LOCUS       DADVXB010000029        24039 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.029, whole genome shotgun sequence.
ACCESSION   DADVXB010000029 DADVXB010000000
VERSION     DADVXB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.029"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            103..855
                     /locus_tag="KB902_000925"
     CDS             103..855
                     /locus_tag="KB902_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6807768.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            852..1766
                     /gene="pfkB"
                     /locus_tag="KB902_000926"
     CDS             852..1766
                     /gene="pfkB"
                     /locus_tag="KB902_000926"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6807769.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            1784..3715
                     /locus_tag="KB902_000927"
     CDS             1784..3715
                     /locus_tag="KB902_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6807770.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(3826..5385)
                     /locus_tag="KB902_000928"
     CDS             complement(3826..5385)
                     /locus_tag="KB902_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBB6807771.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            5540..7774
                     /gene="pcrA"
                     /locus_tag="KB902_000929"
     CDS             5540..7774
                     /gene="pcrA"
                     /locus_tag="KB902_000929"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBB6807772.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            7791..9827
                     /gene="ligA"
                     /locus_tag="KB902_000930"
     CDS             7791..9827
                     /gene="ligA"
                     /locus_tag="KB902_000930"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBB6807773.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            9933..10238
                     /gene="gatC"
                     /locus_tag="KB902_000931"
     CDS             9933..10238
                     /gene="gatC"
                     /locus_tag="KB902_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBB6807774.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            10238..11710
                     /gene="gatA"
                     /locus_tag="KB902_000932"
     CDS             10238..11710
                     /gene="gatA"
                     /locus_tag="KB902_000932"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBB6807775.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            11707..13137
                     /gene="gatB"
                     /locus_tag="KB902_000933"
     CDS             11707..13137
                     /gene="gatB"
                     /locus_tag="KB902_000933"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBB6807776.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            13147..14202
                     /locus_tag="KB902_000934"
     CDS             13147..14202
                     /locus_tag="KB902_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6807777.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEARRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRVIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            14313..15686
                     /gene="rlmD"
                     /locus_tag="KB902_000935"
     CDS             14313..15686
                     /gene="rlmD"
                     /locus_tag="KB902_000935"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6807778.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRTGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGVKPSVIVVDPPRKGL
                     DHRFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            15689..15817
                     /locus_tag="KB902_000936"
     CDS             15689..15817
                     /locus_tag="KB902_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6807779.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            16258..16446
                     /locus_tag="KB902_000937"
                     /pseudo
     CDS             16258..16446
                     /locus_tag="KB902_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
     gene            16524..17537
                     /locus_tag="KB902_000938"
     CDS             16524..17537
                     /locus_tag="KB902_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6807780.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(17604..18638)
                     /locus_tag="KB902_000939"
     CDS             complement(17604..18638)
                     /locus_tag="KB902_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807781.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            18753..20978
                     /locus_tag="KB902_000940"
     CDS             18753..20978
                     /locus_tag="KB902_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6807782.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            20996..22879
                     /locus_tag="KB902_000941"
     CDS             20996..22879
                     /locus_tag="KB902_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBB6807783.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            22860..23834
                     /locus_tag="KB902_000942"
     CDS             22860..23834
                     /locus_tag="KB902_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBB6807784.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         8040 a         4388 c         5197 g         6414 t
ORIGIN      
        1 tttttttttg actgatttat aatttttatg aacgtttttg actgatttat attgcgagta
       61 gaaaaaaaat atgctattat ttgtattgag gtgatcgtga aaatgcttac agaggaacgt
      121 agacaaaaaa tcctagactt gcttgaacag cagaaaatcg tgaaatcaca agatcttgta
      181 aaccttttga atgcttctga atcaacgata agacgtgatt tacaagagct ggagaatagt
      241 gggtttctag aaagagttca tggcggagct aagaaagagc aattattgaa ttttgagcag
      301 aatatgagtg aaaaatcact caaaaacgtt cacgaaaaac agcaaatcgc caaatcggca
      361 gctgaaacca ttaatgacga agatgtcatt tatttagacg ctggctctac tacgttagaa
      421 atgattcctt ttctgcaagg aaaacagatc acagtagtga caaattccgt tcaacatgcg
      481 gcaaatttag ttgatttgga gcttgctacc attattttag gtggaacgat aaagctggca
      541 actaatgctg ttttaggatc taatgcgata gaacaactaa aaaattttca ttttaataaa
      601 gcatttatgg gaatgaacgg tgcccatctt gaacaaggat tcacgactcc ggacccagaa
      661 gaggcagctg ttaaacgttt agccatgaaa aattccgaag agacatttgt attgattgat
      721 cataccaaat tcaaccagtt gtccttcacc tctgttgcac ctttggaagc agccacgatc
      781 ataaccgagc gttgtccatt agaattcgtt aatgaattcc gtgaaaagac aacaattaag
      841 gaggcaatac aatgatttac acagtaacac ttaatccatc aattgattat atcgtacgcg
      901 tagatgggtt aaaactaggc gatttgaacc gaatgaagga agacttcaag ttacctggag
      961 gaaaagggat caatgtttcc cgtattttga aacggatcga ttctcaatct acagcactag
     1021 ggtttttagg agggttcact ggcgaattta tttcgaagtg gcttgaaaaa gaacaaatcc
     1081 agtctttgtt cacaaccgta aaagaagata caagaatcaa tatcaaacta aaatcagata
     1141 ctgaaactga aattaacggt ttgggcccat ctatttcaga tgaagaaatc gatgagttga
     1201 agcaagcatt aggaacagta ggacaaggag atatcgtcgt attgtcagga agcgcgccgg
     1261 ctagcctgcg aaaaggattt tatcaagaac tgattgatat cattcgagaa aaaggtgcag
     1321 atttcgtgat tgatacaaca ggtgatgacc taaaaaatgc acttgttaag aaaccattgt
     1381 tgatcaaacc aaacaatcac gaattagctg agctttacaa tacaaccttc caatctgtag
     1441 aagaaatcat tccgtatggt aaaaaattgc tagctgaagg ggcacagaat gtgctgatct
     1501 caatggctgg agacggtgct ttgctcttca cggaacaagg aacttataaa acgaatgtat
     1561 tagttcgccc attgaaaaat tcagtaggtg caggggattc aatgattgcc ggctttattg
     1621 gggcttacag ccgtacgaaa gatccaatcg aagcctttaa atggggagtt gcttgcggaa
     1681 gcgcaacagc tttttctgat gacttggcag ctcgcgaatt gattgatgag ttgctgccag
     1741 aagttgaaat cacaaaaatt gattagtttc aaggaggata atcatgaata tcaaggattt
     1801 aatggtcaaa gaagcgatga tcatggattt gcaagcgact gataaaaaag gcgcaatcga
     1861 tgaaatggtc caaaaaatgt ttgatgccgg ccggatttcc gatatcgaaa catataaaga
     1921 aggaattcta gcccgcgaag cacaaacttc tacaggtctt ggtgatggaa tcgccatgcc
     1981 tcacgcgaaa aacagtgcag ttaaagaagc aacagtttta ttcgcaaaaa gccaaaaagg
     2041 agtagattat gaagccttag acggacagcc aacttatctg tttttcatga tcgcagctcc
     2101 agaaggcgca aacgacacac atttgcaagc attagcagca ctatctcgat tgctgattga
     2161 tgcagatttc gtaggaaaat taaaagaagc aaatacacca gaagaagtcc aagacttgtt
     2221 ccaaacagct gaagagcaaa aagaagcaga agaaaaagca gaacaagaaa cacaagctgc
     2281 agaagcttct gctcatccag aaagaaaatt cgttgttgcc gttacagctt gtccaacagg
     2341 gatcgctcac acttacatgg cagaagatgc tctgaagaaa aaagcgaaag aaatgggtgt
     2401 ggagatcaaa gtcgaaacga acggttcaga aggaatcaaa aaccgattga ctgctgaaga
     2461 catcgcccgt gcagaaggtg taatcgttgc agcagacaaa aaagtagaga tgaatcgctt
     2521 tgacggaaaa gaactgatca atcgtcctgt cagtgatggt atccgtaaac cagaagagct
     2581 gatcaatcta gcccttagtg gtactgcacc agtattccat ggtgatggaa aagaaagcag
     2641 ttcagaagaa ggaaatgcgg atggtactat cggacaaaga atttacaaag atttgatgaa
     2701 cggcgtatca cacatgttac ctttcgttat tggtggagga atcgctattg cgctttcttt
     2761 catgatcgac caatttattg gcgtgccaca tgatcaatta tcaaatctag ggaattacaa
     2821 tcaagctgct agctggttca accaaatcgg acaagctgca tttggtttca tgctgccggt
     2881 attagcagga tttattgctt caagtatcgg tgaccgccct ggtttgatcg ttggatttgc
     2941 tgctggtgca ttagctaata caggcggtgc aggattctta ggtgcactga ttggtggatt
     3001 cttagctggt tatgtcatcg tatttttacg taaattattc aagaacttac caaaatcatt
     3061 ggatggaatt aaaacgatcc tcttttatcc agtgtttggc ttactgatta ctggtttctt
     3121 gatgttgctg gtcaatgtcc ctatgaaagc aatcaatgat gcattgaacg gtttcttgac
     3181 aagtatgagt ggttcgaatg ctgctttact tggtgcatta ttagctggaa tgatggcggc
     3241 agatttaggc ggtccaatca acaaagccgc ttatgtgttt ggtacagcaa ctttagctac
     3301 gactgttgca actggcggaa gtgtcgtgat ggcttctgtt atggctggag gaatggtacc
     3361 tccattggca attttcgttg ctacacgttt gtttaagaat aaattcagca aaacagatca
     3421 agatgctggt ttgacgaaca tcgtgatggg actatcgttt gtcacggaag gatcgattcc
     3481 atttgcagca gctgacccga ttcgtgccat tccaagtttt attattggtt ctgctttaac
     3541 tggcggatta gtcggagctt tcgggatcaa attactggct cctcatggcg ggattttcgt
     3601 tgtattctta ctgagtcacc cggtcatgta tttggtgttt attgctatcg gagcagtcgt
     3661 atctggtgtg atttatggtt tattgagaaa agctcctgca gcagcagaag catagaaata
     3721 aaaaagaaga ggctggtttt tcccagtctc ttcttttttt atagaatcat atagaatcaa
     3781 gtagtgtaga tgaatagttg ttgtaaaata gtttttccat gttcgttaaa atgattgctt
     3841 caaatttgtg atagaagatt tagcctcgat ttcctgcttg attcttggca agtttgcttc
     3901 atcagtcaag ataaccaaaa tatctcctac attcatgatc gtatcaccgt gagtcaagat
     3961 ttcctgattt cctctgcgta tagagattag cagcatattt ttaggccaat tgaagtctcg
     4021 taccattaat ccgtctaaag aactctctgc cgttactgga aaatcaaaag ttgtccttgc
     4081 accttttagt gaggcggtct gagtatttcc aagtagacgt tccaataatg attcgtaaat
     4141 tggattaccg ccgagaaggt cattgacgat ataagcaaca agagcagcca atcctaaagg
     4201 catcagatga ttaagagagc caaccatttc tgtcactaaa ataattgctg tcagcggtgc
     4261 ttttccaatc gctgtgaaat aaccagccat ggcaataacg acaaaatcct tgatgtagat
     4321 tggatccatc ccgaaatcaa ccataatgtt tccataaaag ctaccgatta aagcccccaa
     4381 tgtcaatatc ggaaggaaaa tcccccctgg aagaccacca ccgtaagaaa tcatggaaaa
     4441 aacgaatcga agaacaaaca aaccgataat cataatgatt ggcaaggaag catgtccaaa
     4501 agctaaaacg atttgattgc ctccgcctag agtactaggc cataaataac caattggcaa
     4561 aatcagcaag aaaggaacga acccgtgaaa ataagctggt aaaggcaatc ggttgtaaaa
     4621 ttttggcaaa gccagcaaga ccttctgata aataaaacct aagatgccta gaagtactcc
     4681 taagatcact aaggaaccat aatatttcaa cggcaaagaa ggaaggtcac ctagatataa
     4741 aacaggtctc aagccgaaaa agtaaagaga gacgaagtta gcagtgattg ctgaagcaaa
     4801 tgatgtcagc caaacaagtg gagaaaagga gtgatggatt tcttctaaaa caaagagtaa
     4861 tcctgcgata ggagcattga atgctgctgc aagtccgcta cttgcaccgc tagaaattaa
     4921 aatcttttct tctgaagatg gactccgaaa caattgtcca gctccttgtc caatggatgc
     4981 gccaagctgt atagaaggtc cttctctacc tagaaaaagg cccgcaccaa ctgaaagtac
     5041 accgccaatg aactttttcc ataaaacaga gaaccagttc attgataatt ccccgcgaag
     5101 ctgtccctct acttgtggaa tcccgcttcc cttgatatcc ggttcatttt tgaccagata
     5161 acccacgaaa aatgctgcaa ggatgcagca aatagctagg ccaattaagt aaatcggctg
     5221 ttcccgactc atttcataga tacttcgaac taaatcgctt agcttttcga tagataatcg
     5281 aaacaggcta acgacgattc ctgtcagcag tccaacaaat attcctttta gaataaaata
     5341 tatctgagtc ttatctaatt tcttgatttt tccttttttt tccattcaaa cgcctcgctt
     5401 tcttttaatt tagcgcgaaa tcaacgaatt gacaaggaaa aatccataaa aagaaacaaa
     5461 tgattttgaa ctagctagtt taatgaaagc caagaaaatg ctataattaa caagattgat
     5521 aaaagaaagg atgttgttaa tgtcatccaa agctgaatta ttaaacggga tgaacccccg
     5581 tcagaaagaa gctgttcttc acactgacgg accattactg ctaatggcag gtgcaggaag
     5641 tggaaagacg agagtgctga cacaccgcat tgcctatttg attgaggaaa aagaagtcaa
     5701 tccttggaac atcctagcga ttacttttac caataaggct gcaaaagaaa tgaaagaacg
     5761 tgtcaatgcg attctcgcat ctggaggcga agatgtctgg gtatcgactt ttcactcgat
     5821 gtgtgtgcgt attttaagaa gagatgttga ttttatcggg tataaccgga actttacaat
     5881 catcgattct tctgaacagc tgaccttgat gaaacggata ctaaaagaac tgaacattga
     5941 tccgaaaaaa tatgatcctc gaagtatatt aggaacaatc tctcaagcaa aaaacagcct
     6001 gcagacccct caggattttg caaaaatgca aggcagttat tacgaagaga ttgcggcaaa
     6061 atgttatgct gcttaccaaa aagagcttca atataatcaa tgtatggact ttgacgacct
     6121 gatcatgaat acgattcgat tatttgaaga acatcctgat tcactcacat attatcaaaa
     6181 caaattccat tatattcatg tagatgagta ccaagataca aatcacgcac agtatacgct
     6241 agtcaattta ttggcaggta gatttaggaa cctgtgcgtc gtgggagatg cagatcaaag
     6301 tatttacggc tggcgcggtg cagatatgca gaacatcttg gattttgaaa aagattatcc
     6361 agatgctgca gtaattttgc tagaacaaaa ctatcgctcc acgaaaaaca tccttagcgc
     6421 agcaaaccaa gtcattgaaa acaatagcaa tcgaaaacca aaaaacttgt ggacagaaaa
     6481 caaagaagga aacaagatca cttactaccg tgcagataat gaacgagacg aaacccgttt
     6541 tatcgtagat cggatgcaag aagagattcg aagcaatcat cggaattacg gcgactttgc
     6601 catcttgtac cggacgaacg cacaatctcg tgtaatggaa gaaactctgt tgaaagcaaa
     6661 tattccttat aaaatggttg gagggcacaa gttctacgat cgtaaagaaa tcaaagatat
     6721 tttagcgtat ttgaatgtgc tggcaaatcc tcaagattca atcagttttg agcgtatcgt
     6781 taattcgccc aaacgaggca tcggaccagg atctatcgaa aaactacgca gttttgcttc
     6841 tcttcatgaa tggccactgc ttgaagcagc gcaaaatgtg gatctggcaa atatcggtgg
     6901 aaaagcagga cagcaattag gtgcatttgg agagatgatc caagaagtca ctcagatgat
     6961 cccatacttg acagtgacag aattgacgaa agaggttttg gatcgtagcg gatatctaga
     7021 agacttaaaa atccaaaata cattagaagc acaagcacgc atcgaaaact tggaggaatt
     7081 tttaacggtc acacaagaat tcgacaaaca attcgaacag caaaatgaag aagacgctga
     7141 tgcaccagaa gaaaaactaa cggtcttctt aaatgatctg gcacttgttt ccgatattga
     7201 caatttagaa gaagatgctt cccaagtgac attgatgact ttgcatgcag ccaaaggatt
     7261 agaattccca gttgtattcc tgattggtct agaagagggg gtttttcctt tatctcgagc
     7321 attgatggaa gaaagcgaac tggaagaaga acgccgtctc gcatatgtgg ggatcacgcg
     7381 agcagaagaa gcgttgtatt taacaaatgc tttctccaga acattatatg gacggacgca
     7441 atataaccga ccttctcgtt ttgtagaaga aatcgatcag gagttactgg aaatcgaagg
     7501 catgcgtcct acgcctaaaa aaacacctgt attcgctaaa aaaacagcat atagctataa
     7561 acagccagag acagcggttg ttccctctaa aagtgctact ggaggggaaa ataacagctg
     7621 gaaacctgga gataaagtca aacacaaaaa atggggtcta ggaacagtcg tccgagtaag
     7681 cgggacgtcg aaggatctag aactagatgt ggctttccca agtcaaggag taaaacgtct
     7741 tttggctgcc tttgcgccaa ttgaaaaagc ttagtagtgg agggtaaatg atggaacatg
     7801 aaatgacgat tgacgaagct gctaaacgag cagaagaact tcgtacaaga ctgaaccaat
     7861 ggtctcgcga atactacgta gaagataaac caacagtgga agactatgtt tatgataaag
     7921 aatacgcaga attagtagca attgaggaac aatatcctga tttgatcacg tctgattctc
     7981 ccactcaacg agtaggcgga aaagtattag aaggttttga aaaagtcact catgatattc
     8041 cgctttacag tttgaacgac gttttcagca aagaagagct gatagctttt gatcaacgtg
     8101 tacaaaaagc agtgggacgt gtagttgact attgctgtga actaaaaata gatggacttt
     8161 ccgtttcttt gcgttatgaa gatggaaatt tcgtgagagg tgcgactcgc ggggatggaa
     8221 ctgtaggaga aaacatcact gaaaacctaa aaactgtccg gtcggtccca atcaaattaa
     8281 aagaaccaat gaacatcgaa gtaagaggcg aatgtttcat gccaaaacgg tcatttgtcc
     8341 aattgaacca agacagagaa gcagagggaa aagatatctt tgcgaatcct cggaacgccg
     8401 cagctggttc tttgcgtcag ttagattcta aaatcacagc gaaaagaaat ctggacactt
     8461 ttttatacac agtagctgat ttcggtccta tgcaagcaaa aacccagtat gatgcgctag
     8521 aagagctaga aaaaattgga ttccacacga atcgggaaaa acgtctatgt cattcgattg
     8581 atgaagtgtg gtcatacatt gaagaatatc atgacaaacg tgtggatttg ccctatgaaa
     8641 tcgatggaat cgtcatcaaa gtgaatgaat tctcgctaca agatcaactt ggttttactg
     8701 tcaaagcacc gagatgggca gcagcttaca agtttccgcc agaagaagtt gaaacgctaa
     8761 tcgaaaacat cgaatggaca gtcggtcgaa caggggtagt aacgccaaca gctatcatga
     8821 caccagtccg agtagcagga acgacagtaa gccgtgccag cctgcataac ggtgattata
     8881 ttaagttgaa ggatatccgc ttgaaagata cagttctgat ttataaagcg ggagacatca
     8941 tcccagaagt ttcgcaagtc gtgttagata aacgacctaa agacagcgaa gaataccaat
     9001 tgcctacaca ttgtccagtt tgtggaagtg aacttgtcca tttggatgaa gaagtagcct
     9061 tacggtgcat caatcctaaa tgccctgctc aaatgaaaga aggtttgaac cactttgttt
     9121 caagaaatgc gatgaatatc gatgggttgg ggccgcgcgt actagaacag atgtatgata
     9181 aaaaactagt agcagatgtt gctgatcttt acaaattgac agaagaagag ttattgacgt
     9241 tggacaaaat aaaagaaaaa tcagcaaata atattttgac agcaatcgac aacagcaaag
     9301 ataattcggt cgagcggttg attttcgggt taggaatccg acatgtcgga gcgaaagcag
     9361 caaaaatttt agcagaacat ttcggtgatc tagaaacatt gagtaaaagt gactatgagt
     9421 cgattattgc gcttgatacg atcggtgata tcattgccga cagtgtagtc acttatttca
     9481 gtaacgaaga agtccatgaa ttgatgaatg aattaaaaca agcaggcgtc aatttcgaat
     9541 acaaagggct tcgaaatgcc caattgcaag aagtcgagtc tccttttaaa gaaaaaacag
     9601 tagtccttac tggtaaacta acacgattta ctcgtgaaga agcaaaagag acgatcgaaa
     9661 atcttggcgg gaaagtgact ggtagcgtat cgaaaaaaac ggatatcgtg gtagcaggag
     9721 aagatgctgg cagcaagctg accaaagcac aagaattagg aatcgaagtt tggacagaag
     9781 atcaaatggc agatgcattg gctaaaagtc gctcagtaga agaatgaaaa atgagttttt
     9841 tcagacaaat ttcaataaac aatttcagac acggcactct tgtgttaaaa tagagagcaa
     9901 agtttttaac tcgtttagaa agaaggggta gtatggcgat tagtgaagaa caagtgaaac
     9961 acgttgccaa attagcaaaa cttgcgttcg cagatgaaga acttgcaagt tttaccgacc
    10021 aattaggtaa aatcatcgat atggttgaaa tgctggaaga agtagataca gaaggtgttc
    10081 catttacgtc gaatgtggtt gaaacagtaa acgtgatgcg acaagatcgg gcgcaagctg
    10141 gatggaaccg cgatgaatta ttgaaaaatg tgccggaaac agaagacggc tttatcaaag
    10201 tacccgcaat catcgataat ggggaggctg gcgcataatg acagaattac acaatcgttc
    10261 tctagaagaa ctgcatcata tgcttgtatc gaaagaaatc actgtacaag atttgacaaa
    10321 agcaacattt gaacgaatca aagaaacaga gcctgaggtc gaagcattca ttacattgaa
    10381 cgaagaaaaa gcattggaac aggcaaaagc tttagatgaa aaagggattg atgaaagcaa
    10441 cgtccttgct ggtattccaa ttggtatcaa ggataatatc gtaacaaaag atatcttgac
    10501 aaccgctgca tctaagatcc tttacaattt tgaaccaatt tatgatgcaa cggtcatgga
    10561 taaaatctat caagcagata tgatccctgt tggtaagcta aacatggatg aatttgctat
    10621 gggtggaagt acagaaactt cttatttcaa gaaaacaaaa aatgcttggg acccaacaaa
    10681 agtacctggt ggctcttctg gtggttctgc agcagcagtt gcagctggac aaattccagt
    10741 ttctttaggt agtgatactg ggggaagtat ccgccaacca gcagctttta acggcatcgt
    10801 agggatgaaa cctacttatg gccgtgtctc acgttttggt ttgattgcct ttgcttcatc
    10861 tcttgaccaa atcggaccaa tgacccgtac ggtgaaagat aatgcattag cattgacagc
    10921 tatcagcggt tatgacgaaa aagacggtac ttcttcaggc gtttcagttc ctgattttgc
    10981 agagggactg acaggcgaca tcaaaggaat gaagattgct ttacctaaag aatacttagg
    11041 cgaaggtgtg gcccctggcg taaaagaagc tgtattgaaa gcagcagaaa cattccgttc
    11101 attaggtgct gttgtggaag aagtcagctt gcctcattca aaatacggtg tggctgttta
    11161 ttatatcatt gcctcatcag aagcaagttc caacttgcaa cgattcgatg gtatccgcta
    11221 cggttatcgc tcagaaaatg tgaaatcatt agatgatgta tatgtcaact cacgttcaga
    11281 aggattcggt gaagaagtaa aacgccgtat catgttaggt acattctcct taagtgctgg
    11341 ttattatgac gcttacttca aaaaagcggg acaagtccgt acattgatca aacgagattt
    11401 tgaaaaagtc tttgcagatt atgacttgat catcgggcca tcttcaccaa cagttgcatt
    11461 cggaatcggt gagaacatta acgatccaat cacaatgtac atgagtgaca tcttaacgat
    11521 ccctgtcaac ttggctggac ttccaggtat gtctgtaccg gcaggtttat cagaaggatt
    11581 accagttgga ttgcagatca tcggtaatta ttttgatgaa aaaacgatgt atcaagcggc
    11641 atatgcgttt gaacaagcaa cagaattcca taaacaacaa ccagctattt taggagggaa
    11701 agacgaatga attttgaaac agtcattgga ctagaagtcc acgtcgagtt aaaaaccaac
    11761 tcaaaaattt tctctccagc gccagctcat tttggtgcag aaccaaacag caatacaaac
    11821 gtgatcgact ggggttatcc aggcgtgctg ccagtaatga ataaagctgc gctggaattc
    11881 gggatgaaag cagctttggc attaaactgt gaaatctcta aagatactca ttttgaccgg
    11941 aaaaattact tttacccaga taatccaaaa gcatatcaaa tttcccaatt tgatcaacca
    12001 atcggtcatg acggatggat cgaaatcgaa gtagaaggta aaaagaaaaa aatccggatc
    12061 gaacgtgtcc atttagaaga agatgctgga aaaaacatgc atggtattgg cggttattct
    12121 tacgttgatt tgaaccgaca aggcacgcct ttgatcgaaa tcgtttctga agctgatatg
    12181 cgttcaccag aagaagcata cgcttatcta gaagcattgc gatcaattat ccaatttaca
    12241 gaagtcagcg atgtgaaaat ggaagaaggc tctatgcgct gtgatgccaa tatttctctt
    12301 cgcccttatg gacaagaaga gttcggtacg aaagcagaat tgaaaaactt gaactcttta
    12361 tctttcgtga aaaaaggttt agcttttgaa gaaaaacgtc aagcaaaagt tcttctttca
    12421 ggaggagaaa tccaacaaga aacacgccgt tttgacgaaa caacgaataa aacagttttg
    12481 atgcgtgtca aagaagggtc tagtgattat cgttacttcc cagagcctga tatcccgaaa
    12541 ttcgtgatcg atgacgaatg gattcaaaaa gtaaaagcta gtttgcctga gatgccagct
    12601 tctcgtcgcg aacgctatat ccgtgagttt ggtcttccag agtatgacgc aatggtattg
    12661 acacttacaa aagaaatgtc tgatttcttt gaagctgttt tggaaaatgg tgcagatgcc
    12721 aagcaagcat ctaactggtt gatgggtgaa gtttctgctt acttgaacag tgagaaactg
    12781 gaattagctg agacaaaatt gacacctgag aacttagcag gaatgattcg tttgatcgcc
    12841 gatggaacga tcagctcaaa aatcgccaaa aaagtcttcc gtgaattgat cacaaatggc
    12901 ggagaagccc aagaagtagt tgaaaaaaat ggttgggtgc aattatctga tccgaacaaa
    12961 ctactgccaa tcattaatga aattttggat aacaaccaac aatctgtcga tgatttcaaa
    13021 aatggaaaag atcgtgcggt tggcttccta gtcggtcaaa tcatgaaagc aactaaagga
    13081 caagcaaatc ctggtgtcgt gaataagcta cttaaagatg aattagcgaa acgatagagg
    13141 ctgaaaatga aaaaagcacg cgtaatttat aaccccacct cgggaaaaga attattgaaa
    13201 aaaaatttgg cggatatcct acaggcatta gaagaagcag gatttgaagc cagcgcctat
    13261 gcaactacac cagaaccaga ttcagccaag aatgaagcac gtagagtcgc agaactaggt
    13321 tttgatctag tagtggcagc tggtggcgat ggcacaatca acgaagtggt taatggaatc
    13381 gctccgcttg aacaccgtcc taaaatggcc atcatcccag ctggtacaac gaacgactat
    13441 gctcgagcat taaaaattcc tagagataat attaaagcag cagcagaagt gattaaaaag
    13501 catcaaaccg taaaaatgga catcggcctt tctgataaca gttacttcat caatatcgct
    13561 gcaggtggct atttgacaga attgacttat gaagttccat cagaactaaa gagtattttt
    13621 ggttatcttg cttatcttgc aaaaggagca gagatgctcc ctcgagtaaa gcccatcaaa
    13681 atgcgcttga agtatgatga aggggaatat atcggaaatg cttcgatgtt tttcctaggg
    13741 ctgacgaact ctgttggagg attcgaacag atcgcgccag atgccaaatt ggatgatggg
    13801 aagttttctt taatcattgt gaagacagca aatatctttg agatcttgca tattgcggca
    13861 ctcatgctga atggcggtcg acatgtcgat gatccaagag taatctatac caaaacaagc
    13921 agtttgttcg tcgaaacaga agatgatatc aatcgaccag taatgatcaa cttagatggt
    13981 gaatatggtg gggaagcacc gatgcatttc caaaatcttc atcagcatat tgagttcttt
    14041 gccaataccg atcagattcc tgatgaagca atcacaggca cagatgaaga agaattagag
    14101 gttgttagca aagaatttgt aaaagaagtc gaacgtttaa cggatgaaga tatcgacggt
    14161 gacggaaaaa tagcagacga aacacctaat caaaagaatt aatcaaaagc cggtgctgaa
    14221 cgtagtaagg tcagtgccgg ttttagttgt gtaattagct gatttatagt agagttcagt
    14281 aggattgaaa aataggctta aaggagcaaa atatgacaga acagcaaata gtaaagaaaa
    14341 acgaacgata tacagtcgaa atcgtcgact tgagttatga aggaatgggg gtagcaaaaa
    14401 tcgatggtta tccattattt atcgaaaatg cactccctgg agaagaagta gaaatactag
    14461 tagtaaaagc aggcaataag tttggatatg gaaaagtcga aacatttatt acacaatcac
    14521 ctgatcgtca gcctgtagaa aacaatgcat tacttcgcac aggtatcgca cctttagccc
    14581 atttgaagta tgaacaacag cttgtcttca aacaaaaaca agtagagcat gtaatggcga
    14641 agattgctaa gatgccagaa gttcctgtac ttccaacggt cggaatggca gaaccatttg
    14701 gctaccgtaa taaagcacag atccctgttc gccgtatcga tggacagtta gccaccggtt
    14761 tttacaaaaa gaatagccat gatctagtcc ctatcgaaga tttttatatc caagatcctg
    14821 tcatcgatca agcaatcaaa gtagtcagag atatcttgca acggttccaa gtacgaggat
    14881 ataatgaaga aaaaaatgaa ggacagcttc gtcacatcat tatccgtcgt ggtcattatt
    14941 cccatgaaat gatggtcgtt ttagttactc gtaaagaaaa attctttaaa tccaaggaaa
    15001 ttgctgaagc cattcatgaa gaattgccag aagtggtttc ggtcatccaa aatatcaatg
    15061 aagaaaaaac aaatgtgatt ttaggagaca aagaaaaagt tttatacggc agagactata
    15121 tcgaagatca gctattagga aaaacctatc gaatctcagc gaagtcattt tatcaagtaa
    15181 atactcaaca agcagagtat ttgtatcaaa cagccatcga atttgccgag ttggataaaa
    15241 aagacattgt gatcgatgct tattcaggaa taggtacaat cggattgtct ctagctgaca
    15301 gagtagataa ggtatatggg atggaagtta ttccagaagc aattgaagat gcacagttca
    15361 atgccttaaa taataaaatc gaaaatgttc attatgaagt cggaaaagca gaaaaagtca
    15421 tgaaaaaatg gcaagaaaaa ggggtcaaac catctgtgat cgtagtagac cctccacgta
    15481 aaggattaga tcatcgtttt attgaatcag caatcgaaat gtcaccagaa cgaatcgtct
    15541 atatctcttg taatccagca acttttgcaa gagatgctaa gttatttgca gaagcaggtt
    15601 acgccgtgaa gaaagttcag cctgtagatc ttttcccgca aacccatcat atcgaattag
    15661 tcgcttcatt cgttaaagga gaataaaaat ggaccaaaaa gaaaaaatga aagaattgat
    15721 caaaaagaaa caaggtggag gccgatccaa acaaatggaa acacctaaaa atgatcgtaa
    15781 aaacatgaga aaaggcccta aaatctttaa taaatagacg tgctaaagaa agactaagaa
    15841 gcgttaactt ttgttattgt ttcttagtct ttttagttag tctacattat tttggcgatt
    15901 tgccaataag gactgttgag ttgtgcaaaa tcaaatctgg gtcagaatga acgtcattct
    15961 gtctcagatt tttcgttatt tcaatttgat taactgattg atcaaaaaga tttttatttt
    16021 catattctca aatgattcaa cactaaatat acatatttga cgcggaaatt attattcgat
    16081 ttgggcggca tcagggggtt atgacgacgt agcagaccca ttattttact caagaaaatg
    16141 tccgtgccta ctatttagaa tacgatagtg aacgtgctgg gagctttgtt cttttagaga
    16201 aagtctctga agataaatta gttgtcttag attttgactg taacgaaaaa tggcgaaatg
    16261 gaagagcacc agcaagtgat tgaccggatc tacgaagcga cacgatatct gcctttggat
    16321 cgtttgtgat taagtcctca atgtggattt gcttcaacag aagaagaaaa tgttttgttt
    16381 gaagaacaat ggaaaaaatt tcttttgtca aaagcattgc agaagaagtt tggggaaaat
    16441 cattaaatca tctaggagag cttgatagga aataacacta tggtataatc agaatgctta
    16501 atactaacta ctgagggagc cttatgaaaa agaaaattct taaatttatc ggatggttct
    16561 tcggaatcat tcttgggatc gcgtttgcaa tctttcttgc cttccagctt tcccccagac
    16621 ctggagcatt cttgatcaac catatgtttt caaatactgt tcaaatcact gataaaaaaa
    16681 cgttcgatca agcagaaaaa aacgtggcga aaaaaacaga tttgacgtat gagtccaagt
    16741 ataaagagaa tacttatgac atctactatc caaaaaacag caaggggcct gttcctgttc
    16801 tattttgggt acatggtgga ggattcgtcg gcggagataa atcgggtgtc aaagaatttg
    16861 cgacaaaatt agtttcagac gccaacatcg cagtggttgc gatgaattat gaattagcgc
    16921 ctgattcaga ataccctaat caagttcttc aagtgaatga actgatcaaa gatttattag
    16981 ctgaagaaaa agacgacaaa ttgctagaca tggaacaatt attttttggt ggagatagtg
    17041 caggttcaca aatcgcattg caatatgcag ctatacaaac gaatgatgcg tatgctaaac
    17101 aaatgaaaat caaacagcta cttccaaaag atagtctgaa aggaaccatt tcttattgcg
    17161 gacctgttga tttgaagcta acagcacagc agcattcgga tgatcgattt atgaagtttt
    17221 tcgtcaaaac cgttgcgtgg tcgttgattg gaacaaaaga ttggaaaacg agtgagcaat
    17281 tgaaagaagc tagtgtggct gaccatgttt ctaaggaatt tccgccaacg tatataactg
    17341 acggaaatgc atactcattc caggagcaag gtcaagcatt agaaaatcgg ttgacagaat
    17401 taaaggtacc cgtgcaatcc ttgttttata cagatacaaa aaaagagatt acccatgaat
    17461 accaatttga ttacacgcta aaagaatcgc aaaattgtta ccagcagaca ttggattttg
    17521 tgaataagta taagtaagag gttgtgaaaa agccgtttcg ttttgagtat gaagaaacga
    17581 agcggctttt cacaacctct ctttcaatac ctttttgttc ttgggataaa actttcccta
    17641 acaatcaatc gtgcaggata agtcaaaatg attggttcgt cccgtatacc gtcaattcgc
    17701 tccaatgcca ttcgaacagc tgcttgccca attgatttcg cattgatttg aacactggtc
    17761 aagccagggg agaggtttgc gattgtctcg atattatcaa agcttgctac aacaatctct
    17821 tctccaattt ggatattttt ttgtttcaat gcccgataga caccaattgc cattggatcg
    17881 ctcccgacaa gaatggcagt aggaagaggg gattcatttt ctaatagatt agtcgcaagt
    17941 acctcacctt gtttttctgt ccagccacct agatgataag acatatattt ttctaagtga
    18001 tgatcgatca taaaatgctg ataggcacgc atcctctttt catttataga aatctgcttc
    18061 ccaccgaatt catccatatc gactttatat cccccgatat aggctattct tttatgacca
    18121 ttttctaaga acaattccag tacggtttta gtcatccgtt caagatctgc atacaccata
    18181 tcgacctctt gctggatgtc agggttatcc acgacgacta tttgcatgtt ttgttttaac
    18241 aaggcggtaa tcgattcttt cgtaacagtc ccaacaacga tcaccgcacc taactgatct
    18301 agatcttccc attgtttagg attatcagat agattataga ttcgattcat ccctaaatgc
    18361 agacgtcgag cttcttcttc catccctact cgcaaatgtt tgtaatagat atcctgttct
    18421 tcgctcgctt tgccgatcgt agagatcaca ccaatcgaag gcattctctt tttgatatat
    18481 ttacgagtac tgatgtcata atccaacgca gcagctgcct ctactatccg ttgccgagta
    18541 gtctgagcca catggatcgt ctgatcgtta ttcaacacac gggaaactgt agcaggagag
    18601 acatttgcct ttcgtgcgac atctctaatt ccaaccattt ttacacactc ctcaaaaaaa
    18661 taaaaaattt ttattgacaa aattgtttag taaacagtat acaggaatta taaaaaaaag
    18721 taaacggttt ccgttttgtt gggagtgaaa tgatggatat tacgcataga aaaacagata
    18781 aaaatttcat cttatttgat gaaaagagcc gagtcttcca tttacgaaat acatttcttt
    18841 cttatctgat aaagatagaa gaaagcaatg tattggcgca tatttatttt ggcaaaccag
    18901 tcaagcagta caaagacaat aaaaattatc cccgaagaga tcgtggattt tcaggaaatg
    18961 ttcccttaaa tcctgaccgg tctctgtcga aagatacact accgcaagaa tactcttctc
    19021 atggcagcat ggactttcga acgcccgcat cgatcattca gcgcaagaat ggatcagact
    19081 tactggatct gagatatgac agccattata ttacagatgg gaagccagag atcgaaggct
    19141 tgcctcaaac ttatgtgatg gacaagtcag aggcacaaac gttggtgatt tcacttaagg
    19201 atagagaaac agcgatttat ttcgatttgt tctataccat atttactgat agagcagtga
    19261 tcacacgatc tgtaaagata agaaatgaaa ccggagaaac aatcaaacta gaaaaagcgg
    19321 ctagtttcca gctagacttt gcccatacta ggcgatttga tgaagtcatt gctttgccag
    19381 gagcacatgt caatgaaaga cagatttcac ggcaatctgt tttatctgga acaaaagtat
    19441 ttgaaagccg tcgaggaacg agcagtcacc atatgaataa ctttattgct ttagttcatc
    19501 atcatacgac agaaaatact ggagaagcga tcggacttca atttgtttat tccggcaacc
    19561 attctttcga acttgaaaaa gatcagatca atcaattgag agtcgtcggt gggatcaaca
    19621 gccatcgttt ttcgtgggaa ttgaatgcag gccagtcttt tcaaacacct gaaatgatcc
    19681 tttcttactc aagtcaggga ttgaacaaaa tgagtcagat ccaccatgag ttgctacgtg
    19741 aaagaatcgc aagaggtcgt catcaatttg ctgaacggcc gattctggtc aataactggg
    19801 aagccactta ctttgacttc aatagtgaaa aaatcaaggc gatcattgat gaagcaaagg
    19861 agctaggcat cgaaatgttc gtattagatg atggctggtt tggaaaaaga gatgcggaca
    19921 attcttcatt aggagactgg ttcgagtatg aaggcaagtt gacaaatgga ttacgtgaaa
    19981 tagcagatta tgctcatagc aaaggattga aatttggttt atggtttgaa cctgaaatga
    20041 tctcggttga ttctgaactg tatcgaacac atcctgattt tcttatgcag gagccaggta
    20101 gaatgccttc tgcttccaga tcacaacatg tactggattt tacaaggtta gatgttcggc
    20161 agacgattga gaaacaaatg agaaagattt tagatacgat tcctcttgac tacatcaaat
    20221 gggatatgaa ccgttcgctt tcagatgtct attcgattac ccttgaccca cagagacaag
    20281 gagaagtagc gcatcgttat atgctcgggc tttatgaact acttgaacat ttgacaactg
    20341 attatccgga aatcttatgg gaaggctgtt ctggtggagg tggacggttt gatgccgggt
    20401 ttatttatta tatgccgcag tcatggacaa gtgataacac ggatgcagtg gagcgtatga
    20461 aaatccaata tggaacaagc cttgcttatc cgatttcgtc catcacagct catgtatcag
    20521 ctgtaccaaa tcatcagacc gacagatcta cttcgttgaa aacaagagga gaaacagcta
    20581 tgagcgctgt ttttggttat gaactggatt tgacaaagct gtctcctgaa gaaaaaaagc
    20641 aagtaaaaga ccaaattata tcctatcaaa cgattcgtcc ggtgatccag tatggccatt
    20701 attatcgttt ggcgagtcct tttgaagaaa atattgccgc atggatgttt gtgtctccta
    20761 aacaagatga agctattgtg tttttaggga ggatactagc ttcagctcaa ccagcgttcc
    20821 atgaagtata tctgatgggg ttagatgatg aggcacttta tcaggaacag acctcgaagc
    20881 ggatattttc gggggccgaa ttgatgacag ttggacttta cttccccgat tttcaaggtg
    20941 atttccaaac agaactgctt catttcaaaa agttatgaga gagaaggaaa aaagtatgaa
    21001 agcaaatata aaatggttag atgatccaca agtttttaga gtgaaccaat caaatgcaca
    21061 tagcgatcat gtttgttatg caacaaggga agaagtagaa accacatcct cccttaaaca
    21121 gtctttaaat ggatcatggc gtttttgtta ttcgccaaat ccttcggtac gaccaaaaac
    21181 attttataaa aaagattttg atgcctgttc ttttgatgaa atcactgttc ctagtcatat
    21241 tgaattagca aattatgaca agatccatta catcaatacg atgtatccgt gggagggaca
    21301 tgtatttcgc cgtccccctt tcacgacaag ccctgagaaa gaggcggaag ggatcttttc
    21361 agctgctaaa gacaatccgg ttggttcgta tttgacgact tttcgattag aagaaggtct
    21421 aaagggaaaa caaatctcga ttcattttgc tggtgtagaa caagcaatgt ttatttggtt
    21481 gaatggtcat tttatcgggt atgccgaaga ttcgttcact ccgtctgaat ttgatttaac
    21541 accttatttg gaagaagaaa atattctagc tgtggaggtt tacaaaagaa gtacagctgc
    21601 attcttggaa gatcaggact ttttccgatt ttttgggatc ttcagagatg tcttcttagt
    21661 tgctcgagga caaaaccatt tagaagatct ttggatcaaa cctcgcttag atgacaaatg
    21721 tcaaaatggc aaacttgaag tagatttgtc ttttgagcaa gtagccaaaa acagtcagct
    21781 gaatgtagcg atactagatc ctgatgggaa ggaaatctat caacagcaat atccgttaaa
    21841 agagcaaatg acgattcgca tcgatggatt tgaaaatgtg gcactgtggg ggcattttca
    21901 gcccaattta tataagcttg aattggagac gatagacgaa gaaaaaagag taacggagta
    21961 tattgactat tccttcggtt ttcgtaaaat cgaaatcaaa gataaaatca tctacttcaa
    22021 tggaaaacgg atgattatca acggggtaaa tcgacatgag tggcatccga aaaaaggacg
    22081 cgccatcact atagaagata tggaaaaaga tttggctatc ataaaaaatg caaagatcaa
    22141 cggcgtacgg acatctcatt accccaacca gatcacttgg tattatttat gcgaccaagc
    22201 aggaatccat gtgatggcgg aaacgaacct cgaatcccat ggctcatggc aaaaaatggg
    22261 cgcatttgag ccttcttaca acgtaccagg tgcagtacct cagtggcagg cggctgttct
    22321 tgatcgagca aaaacgaatt tcgaaacatt aaaaaaccat ccaagtattc ttttttggtc
    22381 tcttggaaat gaatcttatg cggaagaaaa cattcgacaa atgaacgatt acttcaaaaa
    22441 agtagacccc gatcgacttg tccattatga agggaatttt ccaaatccag cattcgaaga
    22501 ttcgatttca gatgtaaaaa gctgcatgta tgcgccacca gaagagatca ttgactacct
    22561 tgaaaataaa gcggaaaaac cgttcatctt atgtgaatat atgcatgaca tggggaattc
    22621 gttaggtgga atggattctt acatgacgtt gcttgatcgt tatgaaatgt accaaggagg
    22681 ctatatatgg gattttaaag atcaggcgat ccaagtgact gatccaatca caggcagaga
    22741 agtgatgcgc tatggcggtg actttgacga taaaccaagt gactatgaat tctcagggaa
    22801 tgggatcgtt tttgcagatg gacaagaaaa acccgccatg caggaggtaa gatattatta
    22861 tgaaaaatac agtaaataaa agtcatatgg atacggaaaa agttgcaatc gtcttcggcg
    22921 actgtacatt aggtgtcaaa tcggggaata cgcattatat tttttcttat acaagaggcg
    22981 gactggaatc gctcaataaa aacggaaaag aatggctata ccgggaaaca cttccagttt
    23041 tttggcgagc aacgaccgat aatgacagag gtagcggatt tggatttaaa tccggtatgt
    23101 ggttaggagc cggattgtat ccaaaagtca aagaaataga agtactggtg gacaataaaa
    23161 agatcgattt gccgattgct ccagtaaata atcaatattc aagtaatgaa tacgctgaaa
    23221 cggttgaaat catttttaca ctggaaatca acacagtacc aaaaacccaa gtgacaattt
    23281 cctaccaaat cgctggagag ggtaaaatgc ttgtcaatat gcattattat ggacaaaaag
    23341 gattaccgga attacccgca ttgggtttaa ggttcattat gccaacgaaa gcaaaatttt
    23401 ttgagtatga aggcctatca ggggaaacat atccggatcg gatggctggt ggtgtcgaag
    23461 gtatttataa agtggcagga ctccccgttt ccccatacct tgttccccaa gaatgcggca
    23521 tgcatatgga aacgaaatgg gtagaactaa caagaaatca aacgttggat aatacggata
    23581 aagatcaaga agatttttcg ttgcgatttg aacagcagga tacgccattt gctttttccg
    23641 ctttaccatt caaagcagaa gaactggaac aggcaacaca tatagaagaa ctaccgccag
    23701 aaagacgaac ggttcttacg atttttgcaa aagtaagagg agtcgggggt atcaatagct
    23761 ggggagcgga tgttgagtca ccttaccgaa tcagcagcga agaggaccat gaaatcggct
    23821 ttattattca gtagcaatct ttagattatt atttgaaaaa cggagtttac aagacaaagc
    23881 tgctttattc tatatgtcat gaacaagaga gtaaaaaagt tctcagatac ttttgttcat
    23941 gactattttc ttcaataaaa ccaattgtta tttttctgaa aaacaaagtt aactatcaga
    24001 aaattaaaaa aagtttcata aaaatgattg acagtcgat
//
LOCUS       DADVXB010000030        23738 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.030, whole genome shotgun sequence.
ACCESSION   DADVXB010000030 DADVXB010000000
VERSION     DADVXB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.030"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            458..889
                     /locus_tag="KB902_000943"
     CDS             458..889
                     /locus_tag="KB902_000943"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807785.1"
                     /translation="MDSLDFLQNNVVKELKEKGFELEDIQKMTVEDIANNLYYPKFRL
                     EVDSQYGESVLYASEKVVSEKDSFMYTLPNGTLIITKPALSKYIERFVVESRKQHSEF
                     GKPFYIKKRNEPWDQDEECLEYERSILKKRDEKPGPPIRKD"
     gene            894..1121
                     /locus_tag="KB902_000944"
     CDS             894..1121
                     /locus_tag="KB902_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807786.1"
                     /translation="MRNYWYVSLTNRYPQPNADDPIRVVQSVQIKKKYSIVEMTREAT
                     PKEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            1118..1402
                     /locus_tag="KB902_000945"
     CDS             1118..1402
                     /locus_tag="KB902_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807787.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELATLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            1443..2015
                     /locus_tag="KB902_000946"
     CDS             1443..2015
                     /locus_tag="KB902_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807788.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPDALVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWDTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            2016..2327
                     /locus_tag="KB902_000947"
     CDS             2016..2327
                     /locus_tag="KB902_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6807789.1"
                     /translation="MIDVSSKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            2318..2578
                     /locus_tag="KB902_000948"
     CDS             2318..2578
                     /locus_tag="KB902_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807790.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEGTTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            2739..3098
                     /locus_tag="KB902_000949"
     CDS             2739..3098
                     /locus_tag="KB902_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807791.1"
                     /translation="MADLQERNRLVSAEERRLNKLFKDIDKDKKKVVSGLITQAARLK
                     ILLDEMWIDISEKGDYELFSQSENQKPYERERPVAKQYNSRDQAYQRVIKQLTDYLPE
                     EKREPTKNAALDGSDLL"
     gene            3095..4738
                     /locus_tag="KB902_000950"
     CDS             3095..4738
                     /locus_tag="KB902_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6807792.1"
                     /translation="MTTLKPFYFDEYVDLYEKGVIPFNKERIQLITYLKNEVLVRDDI
                     YFDEEMIQKFIKYTEKNFFPLAKYQKFITPFIFCYQKEDDEVFFDEILNSIARGGGKN
                     GFMSARDSFFISPLYGVRNYDVTITANSEKQGKVSFKEVYEMVQMRKLEKQFYLTKMA
                     IVNNVTNSIFSYRTNNPKTMDSARDGCLEFDEIHQFESSDLVDIQRSGLGKIKHPRTF
                     YNGTNGHVREGFYDKMLERAQKIFSGENKNDRLFPFICKLDNIDEMDNPKMWSKANPM
                     FEEDSAYSKRLFSTVMKEYKKLEDEPSGRREFVVKRMNFTEGDAESDITTHEKLMATK
                     QELPNLNGRSCVAGFDYASIRDFATVGLLFKIDDKFIWQQHSFARKKFLDTFKLKAPI
                     KDWEKKGLVTIVDEPSIDPRHLIDWLNEKRKIHQIEIVCADGFRMDLLKPLLEKESYN
                     FEFIRNIRGVQSKVAPIIEDGFANERFIFGDDPMMRWYTNNSFIKEDKLGNKTFLKKE
                     PVRRKTDGFHAFLAALYKREEITDMDYEEAFDMLDEIEF"
     gene            4773..5855
                     /locus_tag="KB902_000951"
     CDS             4773..5855
                     /locus_tag="KB902_000951"
                     /inference="COORDINATES: protein motif:HMM:NF028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807793.1"
                     /translation="MKKRYFLFVTIFIIIAICVLTVFLPQITEYLNYRIFTTKVDDSV
                     TSLSRLEFIKICASVFGPILTVMVFVNTLNMQKKTEQKQNELEVKQAKAENERAKKEL
                     LTQIDREFYFLLNMFIEIQKDQNAKQAVIALQKLAIFNEKGFNQDYAFTSKDLSDSEI
                     GSTIEQSGPLKGTVEYIKFETFDVSKSMGNYQTKTKDVATSLHDQKVAILNEQYEKMQ
                     IYLGRYFKMFHRIVKTLNEYYDDYNDFDVKRYTKYIGTLRTQISPAEFQVILFNSLYI
                     KRGFGLGIQLIGSGFFGDDFDFETNQHFETSINEQWFLSLSTVDSDNSIKRQKLSEYI
                     KELGSVEYKKIANFESLYKLFNETKL"
     gene            5899..7071
                     /locus_tag="KB902_000952"
     CDS             5899..7071
                     /locus_tag="KB902_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6807794.1"
                     /translation="MSLFDIFKQSIRNEEPSEWIPDFVYGEEVSARAYLKIMAKNTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWNMSDVIYMEYNNEELERFTR
                     GLFEDYAALFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDRIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIDDVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            7058..7762
                     /locus_tag="KB902_000953"
     CDS             7058..7762
                     /locus_tag="KB902_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6807795.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            7767..8927
                     /locus_tag="KB902_000954"
     CDS             7767..8927
                     /locus_tag="KB902_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6807796.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTAEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVKYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            9003..9281
                     /locus_tag="KB902_000955"
     CDS             9003..9281
                     /locus_tag="KB902_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6807797.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            9262..9633
                     /locus_tag="KB902_000956"
     CDS             9262..9633
                     /locus_tag="KB902_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBB6807798.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            9649..10053
                     /locus_tag="KB902_000957"
     CDS             9649..10053
                     /locus_tag="KB902_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807799.1"
                     /translation="MSNVKFEGVQETIQALEKKYGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIAEVVRKNATYRDYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSELLYFDAVGEEVKKSL"
     gene            10050..10460
                     /locus_tag="KB902_000958"
     CDS             10050..10460
                     /locus_tag="KB902_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807800.1"
                     /translation="MKDMLNIIYEALCLNEYIHSMTYNENTEQYRIKFYEQPETADKT
                     GPMITIRPVDTPNEAYHGSNKELSVEHMIQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFTETNRFVDARRYEGNTKIYDTEY"
     gene            10521..11108
                     /locus_tag="KB902_000959"
     CDS             10521..11108
                     /locus_tag="KB902_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6807801.1"
                     /translation="MTLVGFKKMTIGVFDSTGKIPAANLYVIEGEQNKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            11181..11648
                     /locus_tag="KB902_000960"
     CDS             11181..11648
                     /locus_tag="KB902_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HBB6807802.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            11694..12002
                     /locus_tag="KB902_000961"
     CDS             11694..12002
                     /locus_tag="KB902_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807803.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            12197..18931
                     /locus_tag="KB902_000962"
     CDS             12197..18931
                     /locus_tag="KB902_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6807804.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGFTGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRNLATQLPGSHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKILKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKAMDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDSTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDTVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPSDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPKNAKGTNFHP
                     GGAAMVNDQKGPTYEELITLPSGETFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYAD
                     GIGNITTVSSTLNLDALILAINELTTVLRTQLMAGTTDAKDTKLSDETKVADPIIPDS
                     LSEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGAT
                     WNKNLLNGWNSLTGTFIATINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYG
                     SFIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMV
                     GGIGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHE
                     EYVQMPDGRSFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDL
                     LDDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDG
                     AVNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRY
                     TAAANYAFEKFPSKIAYVITNGRVRDRMGLSGTRSSGQWTNWPDGDHFDHIHLNGSMG
                     SGDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGN
                     DGLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIG
                     KGHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGSNKKETKS
                     EINSVDNRHILQAIEKQSRMTNDLLSLLLSFFKSNNRSDKELALDIQKILIRRT"
     gene            18935..19807
                     /locus_tag="KB902_000963"
     CDS             18935..19807
                     /locus_tag="KB902_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBB6807805.1"
                     /translation="MRTVILRNKLNEEIDLSTEDYFATEMSNLGFEVTKEHIGQWGSF
                     REIGESIELSEFQSSVMISVHGFREQQLYGSLVEFLANGPFELEFSFDSETMIRKCSL
                     KSLSKTEIDSQSSLLTDTLNLYFTSSWYSIKREKLIQNSTSLNTRGKVYSFVRPYVYT
                     KNVWEKKGVFKFSNNSVYLTNSTERMSPLKIRIIGECSNPYWEVIQNSKVVASDGYFI
                     NMKDTQILEVSSLLEDQTAILKDVGGVESSVYQQQDFTKSNFVQAPLGEFSVVFHVGH
                     ANVEIELYEERDLF"
     gene            19804..20853
                     /locus_tag="KB902_000964"
     CDS             19804..20853
                     /locus_tag="KB902_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807806.1"
                     /translation="MILAITLFHRDMNLYNERLISTEFEFGTDEIGEEVSNFITDKYV
                     HVKSGDFLLAKFIPSGKIAYFGVISSQEDKKINCKGLLSLADSEIPTVKISGANYEEH
                     IRRLIEYYLLNDPTKQLKNILEVKTESVTSHSYQAVDTNKRRLNAYIINGFKKYNVKW
                     YVKEIKGKKIYTGIRAVDDSIYIKDNSSEFNDWDVFVQSPGPGNENKLLIVDKAMKDI
                     ENPLVLSTWYLDDENNLTQDSTNKNIALPTVNLVNIYDQTQEDRPSYEEVAKSELKGN
                     AYSHEIKVNVVLNARNINVENIETGMLATIVYKEQTYKSVLTAWRISSSKKNIELTFG
                     NVRSRFMDYFEDNGG"
     gene            20857..21681
                     /locus_tag="KB902_000965"
     CDS             20857..21681
                     /locus_tag="KB902_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807807.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVGAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIEGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TVTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            21699..23735
                     /locus_tag="KB902_000966"
     CDS             21699..23735
                     /locus_tag="KB902_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBB6807808.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQANDRIDKANDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLIANINADSFSQGIGALSVIDDGDEVVVTLDPNHKLEVFKAKSQPALLIGKT
                     YTLSVEIMLEDDFTGDPSTIGLRYIKMPNWASELYTRNALTTAKGVWQKLTGTVKITA
                     TSDNAESWLIMLQNKDANNSLSGRLRLRHAKLEEGSTATSYQPNLLDAPYYLSNKPLG
                     ENIANPTVKFPITLSNEALYAKNASEDFVLGETYTVTIKATKPVSQTIRVYLTQKQFG
                     EFKPVEGLVDTWVATVSIKQLGENTKWVYLSQTPNTSLGPVKIDWLKIEKGDTRTPNI
                     SEYKYFGEGLKDSNNPNDYSWDITPEYTEKGLNDTVSLTEPQSIEGLKNFEDGIQSKG
                     KSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGNDSTILTIP
                     EGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
BASE COUNT         8500 a         3605 c         5019 g         6614 t
ORIGIN      
        1 aaaatatgca tcaaattttg catctttccc ttcaattatt tgagatttaa caatatctct
       61 gacaaaaggt aatgttgcaa ttgctaaatc atgagcgcgt tgttcattgg ttaacatagt
      121 tttcaccttc gtatatttat ttcagcggac cactcgctga taaataaaat tatacactta
      181 gtatttattt tcacaatatt aatttgtcac tgtggcggag ggtagacgct taaaataagt
      241 tcaatacgtc gagggatagc cttaacgttt tatgatttga ccatgcaatg ttcgattcat
      301 tgccagcgat tttagcaact gagggttgga aatgggcgct caaagtacac gagcaaggcg
      361 aggtcgatag taatcgatgg aatcggtgta ggttgctatt acatattaga tcactctttg
      421 agtggtcttt ttattttaca tgaggagtgg cgcgagaatg gattcattag attttttaca
      481 aaacaatgta gtgaaagagt tgaaagaaaa aggattcgaa ttagaagata ttcaaaagat
      541 gactgttgag gatatagcca acaatttata ctatcctaag ttccgccttg aagtagacag
      601 tcagtacggt gaatctgtac tttatgcaag cgagaaagtt gtgagcgaaa aggattcatt
      661 tatgtacact ttgcctaacg gtactctgat tattactaaa cctgcactat caaaatacat
      721 cgagcgattt gttgtagagt ctcgtaagca acacagcgaa tttgggaaac ccttttatat
      781 aaaaaaacgc aacgaacctt gggatcaaga cgaagaatgt cttgagtatg aacgaagcat
      841 attgaagaag cgtgatgaaa aaccgggacc tccaataaga aaggactaac accatgagaa
      901 actactggta tgtatcacta acgaataggt atccacaacc aaacgcagat gatccaatta
      961 gagttgtcca atcagtccaa attaaaaaga agtattccat tgttgaaatg acaagagaag
     1021 ctacaccgaa agagatcgat aagtacaatc ttcgttactg cggccatgga tattggaaag
     1081 acgaatatat tcaacaaaac attgagaggt acatcaaatg aatgataact atgattacat
     1141 caagttgatt gagaagataa gagcagagaa agatatggat gaactagcta ccttattcat
     1201 gaacatcatt agcttggtgg ggttaaagat ggatgaagta gcagcactaa attatttcat
     1261 cgctgagcaa acaattagag cagagcacaa tgctaagttc ttgaaagata gactagatct
     1321 agatgtaaaa ggattaggcg ttgaagggat attcaaagtg caagaagcct tagtgaatgt
     1381 ttatgtcgaa aagatgcaat agcattgaca agtaattatt ggatgttttc aggagggaaa
     1441 ctatgaaatt aaaagattat attagggaag ggtataacat tgtaactaca ccaaatctag
     1501 cttataaaat ccaagaagat tatcccgatg ctttagtgtt tactgataga gctttagatg
     1561 ccattcctat agggaagtta ttagttgatc gttattatag caataatcca gctgttctta
     1621 gtgctaagcc acttcaaaac gcttatgcta ttgaacgctt tacttgcgag tttactggat
     1681 atgagacggt agtaccaatg acaggtgaga caggaagaaa agtaattcaa cagatcaaaa
     1741 agaggattgc tgaattgacg ttagatgatg gaagtaatac gaaccttcta gaaatcaaac
     1801 taagagatac tgactcagta ccagaagttt attataaagg tcaacgaatg gatgagatgc
     1861 cgataggtct tgtcgatatt acttatcatt gggatacgga agaatatgaa tgccaagtac
     1921 caaaaggagc taacgacatc actattgaat attatgattc acataataac aagtacttag
     1981 atagaaaaat cattgggcac aagagagata tgtaaatgat tgatgtttca agtaaacaag
     2041 caagagctag gttctatgga tcaactgagt ggaggaaact tagaagtcaa tgcttagagc
     2101 gagatcatta tgagtgccaa tggtgtaaag cagagggtag actaacaact caacatgatt
     2161 caattcttga agtggatcat ataaaggagc tggagtatca tccggattta gctctagata
     2221 taaacaacct aagaacctta tgcaaagatt gccataacaa aaggcacaac cgtatgaaat
     2281 atcgtggcca acaaaagaaa agaaagtggg atgatgaatg gtggtaagaa aaacagcaaa
     2341 cagagatgat gtcaaacgag cagaagcaat cgctatggtt gataaggcta ttgataagtt
     2401 ggttctattt aagagtcagc tcattgaagg aacaacaact gtagaggata tatctatcaa
     2461 caatagacta ataggtaacg ctaatgaagt aacagggaca tttaatatta atgtagacat
     2521 tgattatacc ttgagtccat ttgcacatat tgtagaaagc aacgagcaag acggctgata
     2581 aatcagtata aagcgaagat atatagagtg aaataccccc ggtcaaaaga ttttgagaag
     2641 aaataaaatt tttgggaacc ggtggatggg gtcaactctg caaataaatg atgctatttt
     2701 cacacgaccc cctccccacg tagaaaggaa gtgagttgat ggctgatctg caagagagaa
     2761 ataggcttgt ttctgctgaa gaaaggcgtc taaataaatt gtttaaggat attgataagg
     2821 ataaaaagaa ggtcgtttct ggtttgatta cgcaagcggc acgcttaaaa attcttcttg
     2881 atgaaatgtg gattgatatt tccgaaaaag gtgattatga gcttttctct cagtcagaaa
     2941 atcaaaaacc ttacgagcgg gaacgaccag ttgctaaaca gtataattcg agagaccaag
     3001 catatcaacg tgtaattaag caacttactg actatttgcc agaagaaaag cgcgaaccta
     3061 caaaaaatgc agcgctagat ggtagtgatt tgctgtgaca acattaaagc cattctattt
     3121 tgatgaatac gtagatttat acgaaaaagg ggtaatccct tttaataaag aaagaattca
     3181 gttaattact tatttaaaaa acgaagtgct agttcgggat gatatctatt ttgatgaaga
     3241 aatgattcaa aagtttatca agtacactga aaaaaatttt tttcctttag ctaaatatca
     3301 aaaatttatc acacctttca ttttctgcta tcaaaaagag gacgacgagg tgttttttga
     3361 tgaaattcta aatagtattg cgcgaggcgg cgggaaaaat gggttcatgt cagcaagaga
     3421 ctcatttttt attagccctc tctacggtgt cagaaattat gatgtaacga ttacagcgaa
     3481 ttctgagaag cagggaaagg tatcttttaa agaagtttat gaaatggtac aaatgcgcaa
     3541 actggaaaaa caattttatt tgactaagat ggctatagtc aacaatgtaa ctaattcgat
     3601 ttttagttat aggacaaaca atcctaagac tatggatagt gcaagagatg gctgcttaga
     3661 atttgatgaa atccatcagt ttgaatcttc agacctagtt gatattcagc gtagtgggct
     3721 agggaaaata aaacatcctc gaacttttta taatggtaca aatggtcatg ttagagaagg
     3781 tttttatgac aaaatgttgg aacgagcaca aaagattttt agtggagaga acaagaatga
     3841 tcgcttgttt ccctttattt gtaaactgga taacattgat gaaatggata atcctaaaat
     3901 gtggtcaaag gctaatccaa tgttcgaaga agattcagca tattcaaaac gtctgttttc
     3961 tacagtgatg aaagaatata aaaaactaga agatgagcca tcaggtaggc gtgaatttgt
     4021 tgttaaacga atgaatttta cagaaggtga tgcagaatca gatattacga ctcatgaaaa
     4081 attaatggct actaaacaag aattgccaaa tttgaatggt cgttcttgtg tggctggatt
     4141 tgattatgca agtattcgtg attttgcaac agtgggtttg ctttttaaaa ttgatgataa
     4201 atttatctgg cagcaacata gttttgctag gaaaaagttt ctagatacat tcaaactgaa
     4261 agcgcctatt aaggattggg agaaaaaagg tttagtgaca atcgttgatg agccatcaat
     4321 tgatcctcgt catttaattg attggttaaa tgaaaaaaga aaaatccatc aaatagaaat
     4381 cgtttgtgcc gacggatttc gtatggattt gctgaaacct cttctagaga aagaatcata
     4441 taattttgag tttatcagaa atataagagg tgtgcagtca aaagttgctc ctattattga
     4501 agatggtttt gcaaatgaac ggtttatttt tggtgatgat cctatgatgc gttggtatac
     4561 aaataattcg tttatcaaag aagacaaatt agggaataaa acatttttga aaaaagagcc
     4621 agtaaggcgt aaaacagatg ggtttcatgc ttttttggca gctttatata aacgagaaga
     4681 aataactgat atggattatg aggaagcatt tgatatgttg gatgagattg aattttaagg
     4741 tatactcctt attgaaaggg gtagttatag aagtgaaaaa gagatatttt ctatttgtta
     4801 caatatttat aataatagca atttgtgttt tgacagtatt tttaccacaa attactgagt
     4861 atttaaatta tcggatattt accacaaaag tagatgatag cgttactagt ttaagtaggc
     4921 tagaatttat aaaaatatgt gcatctgtgt ttggtcctat tttgactgta atggtatttg
     4981 tgaatacttt aaatatgcag aaaaaaacag agcaaaagca aaatgagctt gaagtaaagc
     5041 aagctaaggc tgagaacgag agagcaaaaa aagagctgtt aacacagata gatcgtgagt
     5101 tctatttttt attaaatatg tttattgaaa tacaaaaaga tcaaaatgcc aaacaagctg
     5161 ttattgcttt acagaagttg gcaattttta acgaaaaggg ttttaatcaa gactatgcat
     5221 ttacttctaa agatttatca gatagtgaaa ttgggagtac aattgaacaa tcaggaccgc
     5281 tgaagggcac agttgaatat ataaaatttg aaacatttga tgtaagcaag tcgatgggga
     5341 attatcaaac aaaaacaaaa gacgttgcta caagtttaca cgatcagaaa gtagctatat
     5401 tgaatgaaca atatgaaaag atgcaaatat atcttggacg gtacttcaaa atgtttcacc
     5461 gaatagttaa aacattaaat gagtattatg acgattataa tgattttgat gtgaagaggt
     5521 atacaaaata tatagggaca ttaagaacac aaatttctcc agctgaattc caagtgattt
     5581 tattcaattc tctatatata aaacgaggtt ttggcttagg aattcaactt attggaagtg
     5641 gtttttttgg agatgatttt gattttgaaa ctaatcaaca ttttgaaaca agtatcaatg
     5701 aacagtggtt tctatcacta tcaactgttg acagtgataa ctctataaag cgacaaaaat
     5761 tatctgaata tattaaagaa ttaggatccg tagaatataa aaaaatagct aattttgaaa
     5821 gtttatataa actctttaat gaaactaagc tctagaaata gggctttttt atttttcttt
     5881 gaaaggtggt gaaaacatgt gagcttattt gatatcttta agcagtcaat aagaaatgaa
     5941 gagccttctg agtggatacc ggattttgta tatggagagg aagtatctgc tcgggcatac
     6001 ctcaaaatta tggcaaaaaa tactgtttta gattttgttg caagaactat gtcaacgtta
     6061 gaagttaagt ttaaaaataa agatgggaca tcagactggg attatattct aaatgttcga
     6121 cctaattctg atatgtcagc agctacattt tggcaaaaat ttttttatcg gctcttagat
     6181 gacaacgaag tgttagtaat atttacagat gataatcaat tgctgattgc tgatgatttt
     6241 agtcgaacgg agtatgccgt gtatgatgat gtttttacaa atgtgatggt aaaaaatttt
     6301 gtctttgaac gttcatggaa catgtctgac gtcatttata tggaatataa taacgaagaa
     6361 ttagaaaggt ttacacgagg tttatttgaa gattacgccg cgttgttcgg acggattcta
     6421 gaagttgcaa tgcgtaacaa ccaaattcgt gggtctgtat ccattgattc aacgggaacg
     6481 gcgaatgatg aaaaaggaaa agatggtaag actagatctc aaagattaca agaatatatt
     6541 gataggattt ggaactcttt taaaactaac tcagttgcaa ttgttcccaa agtgaaaggc
     6601 tttgagtatg aggaatacac caataaacaa ggcgtatcga atcaatcgct agatgaactg
     6661 aataagatga agtcgtcttt aattgatgat gttgccaacg ccataggagt acctacggcg
     6721 cttatttatg gtgaaaaagc tgaactggat tcaaatatta aagcttttcg taaattgtgt
     6781 attgctccac tagttaaaaa acttcaagac gaattggtgg caaaaataat tagtcgtcaa
     6841 gagtacaaaa acggggaacg tatagaagtt aaaaaagttc tccaaaaaga tctattagag
     6901 tatgctactc aaattgataa aataacatct ggtggtgcgt tttatattga cgaagttcgt
     6961 gatgaagttg attatgatga gttgccaaat aatgaaggaa aaattcgtat tcgtacgaaa
     7021 aactatgaag aaactgtgaa gggaggtgag aacgacaatg ccgaaagcta aaaaagtacc
     7081 atttcagttt actaacgaaa ttcagaatgg taagcacatt ctcaccttga gtggaaatgt
     7141 acagaaaaaa tattggcgtg atgatgatgt cataaacgct aaagatattc gtgactctct
     7201 agatactgta accgatgata ttgtaatcaa gttgaacagc ccaggcggtg atgtgtttga
     7261 agggattgag atttacaatt atttaaaaga tcacccatca aatattactg tagaagttac
     7321 agggcttgcc gcaagcgcag caacgtttat tgtcgctggt gccaatgatg tgattatgaa
     7381 tgttgggact tctttgatga ttcatgaagc ttctacattt gcttggggga ataaacagga
     7441 catccaaaaa acgttaaacg cattggaaac gatcgatgat tctatcttag ctatttattc
     7501 agataagact ggccaatctg ttgataagtt gcgtgaatgg atgaatgaag aaaaatggtt
     7561 tacagcagat gaagctgtca aatatggatt tgccaattct gtgaagcgtg aagaaccaca
     7621 aaatgaacct caaaatattg cagcgatgat tcaagatgct gttgccgttg caatagcgaa
     7681 tttaaaggaa cctgttacta ataaaatcga acaagaatca aaacaaaaat cattaatcgc
     7741 acgattgcga aaaggagaat aaagatatgt taaaaattac agataaaact gcagatgcaa
     7801 aaaaggcatt taatgctatt tcttcgaaag aagatgcaac acccgaacaa attaatgctg
     7861 ctctagaaga atatgtaacc gccattgcag aagatgccgg caaacaggtg cgtgctgaat
     7921 atgaagaatt gaaaaatgtg acggacaacc gtgtattaga ggctcgtgga attcctacac
     7981 taacagcaga agaaacaaag ttttataatg aagccgtaaa atctggaggt ttcgattctg
     8041 acgtagtttg gccagaaacg attttggaac gtgtttttga aaatcttcaa aacgatcatc
     8101 ctattttagg cctcattaac tttacaccaa ctgtaggtcg tgtcaaagta attagagcac
     8161 gtcgtaaagg tgttgctgtt tttggaccat tgcataaaga ccttgaaggc caactagatg
     8221 ctgaatttgg tgcaactgaa tttgttcaac ttgcgttgac cgcatttttc ttaatttcta
     8281 atgatacctt agatttagga ccacgatgga ttgaccgttt tatcaatctt tctttaagtg
     8341 aagcagtacg tgatgtttgg gctaaaaaaa ttattacagg ttctggtaaa gatgagccaa
     8401 ttggattgct taaagatcta gatggtgcgg tcacaagtgg tgtatatcca gataaagcta
     8461 gcgcagggac attaactttt gcgaaagaga agattgttct tgaacttgca ggggtgatga
     8521 aaaaattatc taaatacaca tacaaagtag atggtgacga tgaaggtgaa gtgaaatacc
     8581 gttctgttgc tggacgagtg tatctaattg ttaatcctgt tgattactgg gatatcgtag
     8641 ctagagttac atttgcaaat ttaaacaatg tgtatgggac tacgatgcca tttatcgctg
     8701 ttgatcatat catcgaatct gtagacgtac cagaaagtaa atgtattgca tacgttgata
     8761 aagagtatga agctactcaa tcaagagctg aaaaagtcta tgtatataaa gaaacttttg
     8821 caatgaaacg cgcaactttg tatgctgtcg acatgcttgg taatggctat ccaacaaata
     8881 atgatgcagc acaagtatat gacttggact ttacagcggg ggagtaatgt cccctgcaat
     8941 tggtgagata acaccgacga ctgatggggc agtcattaat ctttcgtaaa tggggttaga
     9001 gtatgaacac tgaagaattt ataaaagaat ataaggcccg atttcgtatt ttccatactt
     9061 ccgaagatga ggatatcggg aaacagttag agagcgggtt tgccgatata aaatctctaa
     9121 tcggcagttt tgatccttcc acttatgaga aaggaaaaga attagtttat gaacgtactc
     9181 ggtatctacg gaacgaatca ctagagtact tttacgacaa ttttcaaaca atgattatgg
     9241 atgcatcaat tgatctggca ggtgctggat atgccaatta aatcaaatta taagaagcct
     9301 aaaattgtag ctggtgatct aaatacgcca gttacttttt ttgagtttca acctaataag
     9361 ggtccagaac ctggtgatga agaaaaaaag gaactgtatt tttgtacagc actagtttac
     9421 aacccatcaa tgaaagatcg tgacattctt ggcacaaaag aaggcgttac gataaaaata
     9481 cgggatcccc atcaatctta tattcctact aacaaacata aagtaaggat attagattat
     9541 cgatatggag ataaagtttg ggaaataatc gatgtctcac cggatttgga agaaaattca
     9601 attgtaaaga tagtattaga attaattact taaatttggt gataaatgat gagtaacgta
     9661 aagtttgaag gcgttcaaga aacaatccaa gctttagaaa aaaagtatgg agaaaagaaa
     9721 actaagacat taacaaaaaa agcaatcaat gttggcgctg aaaaagtaga aaaacagttg
     9781 caaacggaca tgaccgtttt taaagacaaa ggttatacga tcgctgaggt tgttcgcaag
     9841 aacgctacgt atagagatta caaggcagaa gctgaaatcg gttggaatgg tccacatcaa
     9901 cgatatagaa tcattcattt gaatgaatgg ggatatacac gaaagggcaa acaaattaga
     9961 ccgagaggat ttggtgtaat aacaaaatct cttaagaatt ccgagctgtt gtactttgat
    10021 gctgtaggag aggaggttaa aaagagttta tgaaagatat gcttaatatc atttacgagg
    10081 ctctttgttt gaatgagtat attcattcaa tgacctacaa cgagaatacc gagcaatatc
    10141 gtattaaatt ttatgagcaa cctgaaaccg ccgataaaac aggtccaatg atcacaattc
    10201 gtcctgtaga tacacctaac gaagcgtacc acggaagtaa caaagagctt tctgtggagc
    10261 atatgataca gattgacgtt gaatcgaaat atagagcaac atgcaagcag attcaatatg
    10321 agataaaaaa agagatgaaa aaactaggct ttggccaaat ttccggtcaa gggttagatg
    10381 aatactttac tgaaacaaac cgctttgtag acgcgcgtcg ttacgaagga aatacaaaaa
    10441 tttacgatac cgaatattag aaattaagac acgaaaataa cgtgtctttt tttattaccc
    10501 aaaattagga ggaaaatttt atgactttag taggattcaa aaaaatgaca atcggggtct
    10561 ttgacagcac agggaagatt ccagcagcaa atttatatgt aattgaaggt gaacaaaaca
    10621 aaggggcgac tgtatctgct gaaatcagtg ggctatcaaa agaaccatca aaagtttacg
    10681 gatcgaacat cgcttactat gtctctcaaa aaggaacagg cgatgtttca gctacttttg
    10741 gattgttaga tttaccaaca gaagtaaatg acaaaattct tggttacaaa accgatacaa
    10801 acaaaatcag cttcttggga gaagatactg agccaccata ttgtgcaatt ttgatggaat
    10861 cggaggattt gaacggcgat acagcaatgc ttgcgatgtt caaaggaaaa ttcagtcgtg
    10921 aatctattaa tcttaacact acgacaaatg aagctttcga accagaagca gaagaatatg
    10981 tattttcagc gattgccaat gatgttgaag gtgatgctaa aggccaaaca gtcgcaaaat
    11041 atgttggaga cgaagaagct tctattactg ctttgaaaga gatggtattt cctgcagcgg
    11101 gggagtaact agccccgttg ttggagcaat cactcccact attaatgggg caacagttga
    11161 attaagttag gaggataact atgccagata catttaaaat ctataaaaaa aatggtactg
    11221 aatttacaaa agtcgcagag ggtgaaagtc cactttctat tactggaatt gcagcaaata
    11281 ctcaagttgc taaaggagat tatcaagcta cgcgtgtggt cggaggtcaa gaatcagtaa
    11341 aagtagatat tcctgcattc accactcttc caatttcagt tactggtgtg acgttggata
    11401 aaacgacagc tgaagttgaa caaggcggaa ccttaaaatt aactcctact gtaacaccag
    11461 caaatgcaac agacaaaaca ggaagctgga gcagttcgaa tacagctgta gctacggtta
    11521 ctggaggcaa cgttacagta aaaacagacg ctgaagttgg cggaactaca gaagtttcat
    11581 ttactactac ggatggcggt aaagtagcaa aatgtactat tacagttatt gaaaaagcag
    11641 cgggctagtc ttcggactag cttttttatt tggaaaataa tggaggaatc taaatggcaa
    11701 aagtaagaat tgaattgaaa gaagaatcag gaaagaaagt ctatgaaaac atagacacaa
    11761 cagggaaaga ttatcgaaaa gctttagaaa caatcaaaaa gctaaatgaa gacggagtaa
    11821 tgatttggaa tcgtttagac atttatttgg attttgctgt aggtatcttc agggatagca
    11881 aattgacagc tgaacaaatt cttgatggct taccatctga gaaggtaatg agcacattgg
    11941 acgacatcct aggagaagta atggggattg aaagtaatcc agacccagac gcaaaaaagt
    12001 aacacccgaa gaagcagaag aaatgtactt aaacctatgc agagagttag tgaaagcggg
    12061 atggtcacta tctgacatag aagataattc ctttgaaatg atgatgaaaa ttgcgtgcac
    12121 ttcgcctaag aaagagaaac aaaaagaagt tgatcttaaa gacttcttga aatccatgta
    12181 gagaggaggt aaacatatgg caaatggaaa acctttaggc aatatgatta tcaaactaga
    12241 cttagacagt tcagcttttt caaaaggtct agccggagct aaaaacgctg ttaaccatca
    12301 aatgaaagca atgaaatcac agatgcaagt aatgaactct tcaggaaatt ctctcggtgc
    12361 tttacaagca aaatacaatg gtttaggcgg agttctacaa gcaaatgaaa agcaagtaga
    12421 attgctcact aaggcttata aggatagttt tgactctaac ggaaacgcta ctgcttcgac
    12481 tgctaaatac gctaatcaat tgaatcaagc aacagctaga tcagcaagtt acgaatctca
    12541 gatgaaaaca actgttggac agattgctcg gatgaaagtg gaaacggaag ggtttacggg
    12601 gaaactaaag gctaattctg atgtattgat taattctggg aaaaaaattg aagcctttgg
    12661 taaaggagtt tctgggatag gatctgccct aactgttgga gtaacagctc caatagtggc
    12721 aggcgcaact gctgttacta gtgcagctat ttcatgggaa agtgcttttg caggtgtaaa
    12781 aaagacaaat gatgaagttg tagactcgaa tggaaacgta gtttattcct atagcgactt
    12841 agagaaaggt ctgcgtaatc ttgccaccca attacctggt agccatcaag aaatagcaaa
    12901 tgtagccgaa gcagccgggc aattaggtat aaagactgaa aacgtagtta gcttcactaa
    12961 aacgatgata gacatgggtg aatcgactaa tatgtcggct gaaactgcgg caacttcttt
    13021 agcacgattt gctaatatta cccaaatgtc tcaaaaagac tttgataaat taggatcagt
    13081 cattgttgat ctaggtaaca attttgctac aaccgaatca gaaatcactg aaatgggatt
    13141 gcggttagcg ggagctggta aacagattgg aatgagccaa ggcgaaattc taggatttgc
    13201 tactgctcta tcttctgttg gtgtcgaagc tgaagcgggt gggtctgcct tttcgaaggt
    13261 catgatccag atgcaactag ctgtagaaaa aggatttggc gcttttgatc agctgaaaca
    13321 gatggcagaa gaacaaggtg ttccgtgggt taatttagta aatgctgtga gagacggtgg
    13381 aaaatcgtta aaagcagtat cagagcaaat gggattcact tcatctgatt taaagaaaat
    13441 gtataaagaa gcggacaatt cgaaaagttc gcttgaaaat tttgcgaatg tggcaggtgt
    13501 tacaagtgaa caattccaga agttgttcaa gagtgatcct tcagaagcaa tcatcaagtt
    13561 cattcaaggg ctgaaagatt cagaaaaaca tggtacttca gcaatcaaag ttctggatga
    13621 catggatata aaagaagttc gactacgcga cagtttattg agagctgcaa atgctagtga
    13681 catattcaaa ggagcaattg aaaaaggaaa cggcgcgtgg aaacaaaata cagctttaac
    13741 aaatgaagct aataaaagat acgaaacaac tgaatcaaag ctaaagatat tgaaaaacga
    13801 agtgattgat acagcaatcg atcttggagg tccatttgta gacgcgttgc gtgatggtct
    13861 aaatgtatcg aaaccattga taaaaaactt agggaatatg gcgaaagctt tctcagctat
    13921 gagtgatgat caacaaagaa acattatcaa atgggttgga ttagcagcag cagctggtcc
    13981 agcgctgaag cttttaggaa ctggtacttc agtaataggt aaagttactt caactactgg
    14041 aagattgacg aaaagccttg ttgatttagc agcgaaagca gcagaaaaga aggctatgga
    14101 tgcctttgca tcgtcggtaa caacagctgg tgctgcagct gcaaagacag caggagctgg
    14161 aggtattggc gggttagtcc ctatgatggg aaaaacagct agtgctgcaa gtactgctgc
    14221 gggcgccagc ggaataggcg caatgacaac gtcactaggt ttgttaggtc ctgctctact
    14281 tggtattgtt ggcgttggtg gcgcactggc agttggctat ggagcatgga aattatttgg
    14341 tgaagaagct tggaattcct cgcaaagagt aaagcaatgg ggaacagatg tcggtgagga
    14401 gatagatagt actcttgacg gagtacagaa gaatattgaa ggtgcaaatg gtcaattcgg
    14461 tcttctcaaa gagggtttta ctgttgatga tgcaaataat atggcggcta atttcgcaac
    14521 cgctggaaca tctttggaaa catctttaac gggtagaata aaggcattag acgatgcact
    14581 aaaagggcta cctcaatcag ttcaggatgc catgaaagaa gtagctgaat cagaagaaga
    14641 aaccttaggg caatctcttt ctaaaataaa agacaacaat gaagaaataa aaaaaatcag
    14701 agaaagagcc gcaaatcaga acagagactt gactgtttca gaactacaac agatacagga
    14761 tctaatgaaa ggaacttctc aagcgtatgt ggatacgctc gatgtttctg ctaaagacag
    14821 aaaaaagata ctatcagcca tgaatggtga tgttgcacaa gctacagaag aagaagcgaa
    14881 gacgtggtta caatctttag cgaaacaaaa agctgcaact accgaaaatt atagacaaat
    14941 gcttgaagaa aaaaaggcgg ctttaaagga aaagggagta agcaaagaat tcattgatgc
    15001 attagaagat gaaatgaatg attacatcaa aactacaaat caaggattcg atagccaaat
    15061 agctgctata acaaataaat atccacaatt gattaacgaa gtgagtttat caaatggtca
    15121 attatttagc aaaacggcag ctgctatgga caatactggt cagtatacaa aagtttttct
    15181 cgaaagtaat gaaaagattt tagcccaagc gaagaaaaca tcggatgaaa tagcagataa
    15241 tgccgaaaaa aatgcagaac aacttggtat ggtagctgat gaggctacgc atgctggatc
    15301 aacttggaat ggcttagttt tagacgaaaa aacaggaaaa gtaaaaacta atgtacaaga
    15361 agtagtgaat gaagcaacga aggatttcac taaatggaat gaattgaaac ctgttgttca
    15421 tgatgcgaaa ctaacaacga atgcaaaaga tgtcatttcc atagcggcag tacaaaatgg
    15481 ctattgggat gatatggaat ggaaagaaaa agaagcatta ttagaagatg agtgttctaa
    15541 aaatgtatac aaggctttag aaaatgctgg taaatggaat gagttagata ttccttctaa
    15601 agaagcaatc ctaacttcaa atactcctga agttatgggt gaaactctca tgaatttggg
    15661 attatgggat acttacaaac ttcaagtgaa agatttagat ttgaatgcgt ataaagtata
    15721 cgatgctatc gatggatcag aagaaaaatt aaatagttgg gctcaattag ataaccccac
    15781 aaaagaattg ttattagata actcagattt ttctacaaaa ctttttaatt ccgaagaaat
    15841 gtttaaacgt tggaatcagt tatcatctaa tgcaaagttt ctttcggcta ataatactaa
    15901 atttacagag gttcttttat catctgacag aatgtggaat caatgggtaa accttcctga
    15961 taatgagaaa agattacttg cagataacga agatttagct accactgttt tatcttcaga
    16021 agaaatatac ggaagatgga ctcaattacc agataatcaa aaatatatgt tagctgacaa
    16081 tactgactta gcaaacaaaa tattcgcttc agaagaatca tggaatgcat ggaaagcaat
    16141 tccagacaca gttaaaaact tgcttggtaa taatattgat ttactggcta aagtgaaaga
    16201 cgggactgta agtgtagaag aatataacaa agttatgcca cttcttaaaa ctctatatgg
    16261 agataacgtt aatttaaaag aggcaatcag tggggctaaa agctctatag agaattacaa
    16321 caaaaatatt tttcctagtg ataaaactgc agtaggacac gatgaggctt cacaagctgc
    16381 taaagatgca tttgaagcgt tcaacatctt ccaaacaaaa ataccagata aaattactaa
    16441 aactgtatca gctgacttta taggtcctat gccgaaaaat gcgaaaggaa caaacttcca
    16501 tcctggcgga gcagctatgg taaacgatca aaaagggcct acttatgaag agcttataac
    16561 cttgccaagc ggagaaactt ttatacctaa aggacgtaat gtcgttttag acttaccaag
    16621 aggttcgaaa gtactgaacg ccactaaaac taaacgtcta gtgcctaaat atgctgatgg
    16681 tataggaaac ataacgacgg tttcatctac gctaaactta gatgctttaa ttttagctat
    16741 taacgagcta acgacggtat tgagaactca actgatggca ggaactactg atgctaaaga
    16801 tactaaacta tcagatgaaa caaaagttgc cgatccgatt attccggaca gtctttctga
    16861 aaaatcagat cagtatctag gaattggagc tcaatggtta actaatctaa tgaatggttg
    16921 gaactcagcg gttcctcaat atatgaatag tgaaatggtt tttattacaa actatctcaa
    16981 tgcgctaaaa cttcaaaaca atcctaatta tacgcaagga gcaacatgga ataagaactt
    17041 actgaatgga tggaatagtt taactgggac ctttattgct acaatcaatt cattttgtaa
    17101 tcaagcaatg gtcacgctta gaaactacaa cactcctatg tacaacaatg gccgaacgtg
    17161 gcagcaaaat aatcttaatg gttggaattc attgtatgga tcattcatag cccgtgtaaa
    17221 tcagcttggt aacgattcga ttaacaacct tcgttctaaa agtggtggtt tttacaatgc
    17281 agggacattc ttgttgcaat ctttaataaa cggaatgaat tcgttaggta attctctttc
    17341 tactacaatg aacaatgtcg ctaatacaat ggttggtggt ataggcaaag gagttaatgg
    17401 cgtcatatcg ggagttaact atgtgcttaa ggaagtcgaa tcaagtaaga atatcggaaa
    17461 ctggccaatt ccacaatacg ctaagggaac tgatggacat cctggtggac ttgctatgat
    17521 taatgatcaa aaaggcctag ttcacgaaga atatgttcag atgccagatg gacgtagttt
    17581 tattgccaaa ggtagagatc ttcttgttaa tttgcctaaa ggtgctcagg tcttaaatgc
    17641 ttctttaaca aagaaattaa aggaacgttt aaatattcca cactacgaaa aaggtattgg
    17701 caatttagat attgttgatt tgttagatga tgaaaaaaga atgttagaat tcttaactag
    17761 caaagttgat ttttcaggca ttaatgaacc atggcttgat atgactaaat caggaacgtc
    17821 attaatgtcc aaagctgcaa atacaatgct tcaatcaaaa ttaagtgaat tcttcactca
    17881 tggcaatttt gatggtgcag taaatgccaa tggtgtttat caatatttag ttgatgtggc
    17941 acagaaagta atgggtaagt tccccggact tacagtaact tctggatatc gagcaggaga
    18001 tgcctactat cacggaaaac ggcaagctat cgacttggct tatccaggta tttctggaga
    18061 tccgagatat acagcagcag caaattacgc ttttgaaaaa ttcccttcaa aaattgcgta
    18121 tgtcattacg aatggacgtg tacgtgaccg catgggatta tctggaacaa ggtcaagcgg
    18181 acaatggacg aattggccag atggcgatca cttcgatcat attcatttaa acggttcgat
    18241 ggggtctggc gatatattca atggaggagt tggaggaagt ggtgttgcac gctggcgttc
    18301 ttatgtgtct aaagcattga aaatgaatgg attaccagct acagcagcgt atataaatgc
    18361 ctggatgtcc caaatccaaa cggaatctgg tggtaatgag aaagcaatcg gcggcaatga
    18421 tgggctcgcc gaaggcaatg caacaggatt acttcaaacg aaacccggaa cttttgcagc
    18481 taacgctttt cctggtcacg gaaatattat gaacggattt gataacatgt tagcagcaat
    18541 caattatgct aagaaacgtt acggagttgc aggtatgttg caagttatcg ggaaaggaca
    18601 tggatatgcc aatggcggct tgattaccaa agacggacta tatcgagcag gagaaggaaa
    18661 taaaccagaa atggttattc cattgacaag aaaaacaaga gctatcgaac ttatgggtca
    18721 agcattagcc ttcctttctg gaagcaataa aaaagaaacg aaaagtgaga ttaattctgt
    18781 agataataga catatcctac aagcgataga aaaacagtct cgtatgacaa atgatctgct
    18841 atcattatta ctctcgtttt ttaaaagtaa caatcgatca gataaagaac tagctttaga
    18901 tattcagaaa attttaatca ggaggacata gtatttgagg acagtaatat taagaaataa
    18961 attgaatgaa gaaattgatt tgtccacaga agattatttt gctactgaaa tgtcgaatct
    19021 aggttttgaa gttacaaaag agcatattgg acaatggggg agtttcagag aaataggaga
    19081 gagtattgaa ttgtctgaat ttcaatcatc agttatgatt tctgttcacg gatttagaga
    19141 acaacaatta tatggttcat tagttgaatt tctggctaat ggaccttttg aactagaatt
    19201 ttcttttgat tcagaaacaa tgatcaggaa atgtagtttg aaatcattat ctaaaacaga
    19261 aattgattcc caaagctcat tgctaacaga tactttgaat ctatatttta cttcaagctg
    19321 gtattctatt aagcgtgaaa aattaataca gaattcaact tctctcaata cacgtggaaa
    19381 agtttactca tttgttcgac catatgtcta caccaaaaat gtatgggaaa agaaaggtgt
    19441 atttaagttc agtaataatt ctgtatattt gacaaatagt acagagcgaa tgtctccgtt
    19501 aaaaataagg attattggag agtgctcaaa tccatattgg gaagttatcc aaaactctaa
    19561 agtagtagct tcagatggct attttattaa tatgaaagac acacaaatat tagaagtgtc
    19621 tagtttgcta gaagaccaaa cggcaatttt aaaagatgta ggtggagttg aatcttctgt
    19681 ttatcaacaa caagatttta ctaaatcaaa cttcgtccaa gcgcctctag gagaattcag
    19741 cgttgttttt catgttggac atgcaaatgt agagattgaa ctttatgagg agcgtgatct
    19801 attttgattt tagccattac cctctttcac cgagatatga atttatataa cgaacgttta
    19861 atttcgactg agttcgaatt tggaacggat gaaattggag aagaagtaag taattttatt
    19921 acagataaat atgtccatgt aaaatcagga gattttctac tagcaaaatt tattcctagc
    19981 gggaagattg cttattttgg agtgattagc tcgcaagaag acaaaaaaat aaattgcaaa
    20041 ggattactca gtttggccga tagcgagata ccgactgtaa aaatatcagg tgctaattat
    20101 gaagagcata ttcgacgact gattgaatac tacttattga acgatccaac aaaacaacta
    20161 aaaaatattt tggaggtaaa aacagaaagc gttacttctc attcttatca agctgttgac
    20221 acaaataaga gacgattgaa tgcatatata ataaatgggt tcaaaaaata taatgttaaa
    20281 tggtatgtca aagagattaa aggtaaaaaa atatatactg gtattcgagc agttgatgat
    20341 tcaatttata ttaaagataa ttcatctgag tttaatgact gggatgtttt tgtgcaatct
    20401 cctggaccag ggaacgagaa caaattattg atcgtagata aagcaatgaa agatatagaa
    20461 aatcccttgg tattgtctac gtggtattta gatgacgaaa ataatcttac gcaagattca
    20521 acgaataaga acattgcatt gcctaccgtt aatttagtaa atatatatga tcaaactcaa
    20581 gaagatagac cttcttatga agaggtagct aaatcggagc ttaaaggcaa cgcctattca
    20641 catgaaatta aagttaatgt tgtgctaaat gctagaaata tcaatgtaga aaatatcgaa
    20701 acaggaatgt tagcgactat tgtttacaaa gagcagactt acaaatctgt tctaactgcc
    20761 tggcgaatat ccagcagtaa aaagaatata gaattgacat ttggtaatgt ccgaagtcgt
    20821 tttatggatt attttgaaga taatggggga taaaaaatgg ttagcaatgt ggatggatat
    20881 caatttgaaa acgtgaaagt aagcgcagaa aatgatgcta gactttatca cgttttatat
    20941 aatcggaaaa atcaggttat tgatggttac gatcagtcta tgaatttatc ttcaagcgga
    21001 ttaacagtaa aagttggtgc aggagcagcg attattcaag gtcgtatggt cgttgttcga
    21061 caagaagaaa gtataacagt tccagcaaac tcaagtggtt atatagcatt aacagtggat
    21121 ttgacacaag aagttatacc tggatctatt cttccagaat cggaagaata tgaatggact
    21181 aataatcaag tcaagctaga atttataaca aaagttatag aaggtaattt aaacaatggt
    21241 gataaggtct ataatttacc actatgctca gttacttcta ctggatcaac tgtttcaatc
    21301 tcaaagatat cggatagtta cgagctgact ctctctaaag gagaaatttt gtggaggggg
    21361 actgcgttaa tgcatgatac tcaaactgtc caaccttcaa aaaaaatttg gcagacagtt
    21421 tcaggttttt tattagtatg gctcccctac gaaaacgggc aagcaattga ggatagatat
    21481 gtaactacac ctttttataa ggaacgtgta actgttacta atgttttagg agaaattgtt
    21541 tcaggatttg atgactatca caaaaagtgg tttagtaaac gaataaacta taattcgaat
    21601 actaatatat ttacaggtgc agcaagcaat gcaagtggag ataacgcaaa tatggtgctt
    21661 aggtatatag tttcttttta gttaggaggt atggaaaagt ggcaaattta gaaattaaat
    21721 tatctgcaaa taagagacag ccttatctac gtcaccgtgt tgttggtaga gttggtgatg
    21781 gggggctcac aacaatcaat gtacaacttc ttgaggaaga tgaaattaca ccttttgtaa
    21841 ttaatctaaa cggtactttg aaatttgtgg gcgaagtttc aaacggtaac tataccgagg
    21901 gagaaccaga aataatcgat tcgactaatg ggttaattag ttacacgttc actaagtcaa
    21961 atttcagcac gagtcatcaa ttcaaacaag catattttga atatgtagat cctaacggca
    22021 aaaaagtaac ttttcagaac ttcatcatag acgtgttaga acgagtggat attaattcgg
    22081 agcaagcgaa atactatatt tcttcattgg aaaaattaca gagtgaaatg caaaccactt
    22141 tcaatcagtt cattagtgat aaacaggtcc aatacgatca aatctactcg aaatataacg
    22201 aattagtaag attgataaat gaatcagata agcaagcgaa tgatcgtatt gataaggcaa
    22261 atgatcgtat tgatcaaacc aatcagcaaa tcggcgatct cggcaagctg aaaaagatgt
    22321 acagtaacag catcgacttc ggggactatg attatagtgg gaatccgaat ttaatagcca
    22381 atataaacgc tgacagcttc tcgcaaggta ttggtgcttt atctgttatt gatgatggtg
    22441 acgaggtagt ggtcacgctt gatccaaacc ataaattaga agtattcaaa gcgaaaagtc
    22501 aaccagccct gttaataggc aaaacatata ccttgagtgt agagattatg ttagaagatg
    22561 atttcactgg agaccctagt acgataggcc taagatatat taaaatgcct aactgggcat
    22621 cagaactata tacgcgtaat gcattaacta ctgctaaggg tgtatggcaa aaactaactg
    22681 gcaccgttaa aattactgct acgagtgata acgctgaaag ctggcttata atgctacaaa
    22741 ataaagacgc taataacagc ctatctggta gactacgttt gagacacgct aaacttgaag
    22801 aaggctcaac agccacatca tatcagccta acttactcga tgcgccgtat tatttgagta
    22861 ataagccttt gggtgagaat attgctaatc ctacagttaa attcccaatc acgctgagta
    22921 acgaggcact ctatgcaaaa aatgcatcag aggattttgt tttaggtgaa acttatactg
    22981 tgacgataaa agcaactaag cctgtctcac aaacgattag ggtttattta actcaaaaac
    23041 aattcggtga gtttaaacca gttgaaggat tggttgatac atgggtcgcc actgtgtcaa
    23101 taaaacagct aggggagaac acaaaatggg tatacctttc tcaaacgcca aatacttctt
    23161 taggtcctgt taaaattgac tggctcaaaa ttgaaaaagg cgacacacga accccaaata
    23221 ttagtgaata taaatacttt ggtgaaggat tgaaagatag caacaatccg aacgactaca
    23281 gctgggacat cacgcctgaa tatactgaaa aaggcttgaa tgatacggtt agtttgactg
    23341 aaccgcaatc catcgaagga ttgaaaaatt tcgaagatgg tattcaatca aaaggaaaat
    23401 ctgtattgac atcagacgac aacaaatatg aagtcgtaac cttaacagtt acaaacggga
    23461 ataccggatc agcaaagctt tatcgtgaag gaaaaaccgt cactatttat ttttttgcgt
    23521 tgaatgggaa aagcagtggt ggaaatgatt caacgatact aacaattcca gaaggctatc
    23581 ggccaccaat tagttttgag caactggttg gctcgataga ccgttctact ttgaacagtg
    23641 ctcagttatc tattggtgca gatggagcca ttaaatggcg aagaaactca agttatggat
    23701 cggattatac ctttgcaatt acttacacga tttagaaa
//
LOCUS       DADVXB010000031        23343 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.031, whole genome shotgun sequence.
ACCESSION   DADVXB010000031 DADVXB010000000
VERSION     DADVXB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.031"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(13..2157)
                     /locus_tag="KB902_000967"
     CDS             complement(13..2157)
                     /locus_tag="KB902_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6807809.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2514..3887)
                     /locus_tag="KB902_000968"
     CDS             complement(2514..3887)
                     /locus_tag="KB902_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6807810.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3887..4282)
                     /gene="rbsD"
                     /locus_tag="KB902_000969"
     CDS             complement(3887..4282)
                     /gene="rbsD"
                     /locus_tag="KB902_000969"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBB6807811.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4310..5227)
                     /gene="rbsK"
                     /locus_tag="KB902_000970"
     CDS             complement(4310..5227)
                     /gene="rbsK"
                     /locus_tag="KB902_000970"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBB6807812.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5335..6348)
                     /locus_tag="KB902_000971"
     CDS             complement(5335..6348)
                     /locus_tag="KB902_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6807813.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6429..7028)
                     /locus_tag="KB902_000972"
     CDS             complement(6429..7028)
                     /locus_tag="KB902_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6807814.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7214..7915
                     /locus_tag="KB902_000973"
     CDS             7214..7915
                     /locus_tag="KB902_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807815.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7925..10636
                     /locus_tag="KB902_000974"
     CDS             7925..10636
                     /locus_tag="KB902_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807816.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11087..12715
                     /gene="treC"
                     /locus_tag="KB902_000975"
     CDS             11087..12715
                     /gene="treC"
                     /locus_tag="KB902_000975"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBB6807817.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12775..13956)
                     /locus_tag="KB902_000976"
     CDS             complement(12775..13956)
                     /locus_tag="KB902_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6807818.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14208..15731
                     /locus_tag="KB902_000977"
     CDS             14208..15731
                     /locus_tag="KB902_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6807819.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(15800..16528)
                     /locus_tag="KB902_000978"
     CDS             complement(15800..16528)
                     /locus_tag="KB902_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6807820.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16541..17821)
                     /locus_tag="KB902_000979"
     CDS             complement(16541..17821)
                     /locus_tag="KB902_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6807821.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17962..18564)
                     /locus_tag="KB902_000980"
     CDS             complement(17962..18564)
                     /locus_tag="KB902_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6807822.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18809..19015
                     /locus_tag="KB902_000981"
     CDS             18809..19015
                     /locus_tag="KB902_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807823.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19327..20046
                     /locus_tag="KB902_000982"
     CDS             19327..20046
                     /locus_tag="KB902_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6807824.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20127..20810)
                     /locus_tag="KB902_000983"
     CDS             complement(20127..20810)
                     /locus_tag="KB902_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBB6807825.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            21028..23214
                     /locus_tag="KB902_000984"
     CDS             21028..23214
                     /locus_tag="KB902_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6807826.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7765 a         4204 c         4573 g         6801 t
ORIGIN      
        1 ttttaattta ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa
       61 caaggttagt acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg
      121 tcttgccgta aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc
      181 gttgttgacg cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt
      241 ccatttgatt ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc
      301 agttgttgct gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat
      361 cgcgttcaat ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt
      421 tgcttctttg tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc
      481 agtcagtcca tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata
      541 tttacggaat tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt
      601 gaaggtcacg ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc
      661 gcttgataat aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga
      721 tgcgtagatt ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa
      781 ttgatcagtt gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga
      841 tgagccgcct gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc
      901 aaaatcaggc gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc
      961 atggataaat tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg
     1021 tccccagaag acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata
     1081 ttgctgttcg cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata
     1141 agtcaaacca gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc
     1201 aagatgcttg aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa
     1261 tacagcatca attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat
     1321 accgctttga tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga
     1381 accattgttt ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg
     1441 gtttgtttga ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt
     1501 tgaaccatta ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg
     1561 tgtactaggg acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc
     1621 tttaaattct gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata
     1681 atttacttct ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt
     1741 aatagtgtaa gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat
     1801 atccaaaggt tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat
     1861 caaagaagga gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc
     1921 agccggatca atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg
     1981 gtcttctgta aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt
     2041 tgtgactgtt tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac
     2101 agacggagca atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat
     2161 aaactagtcc ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt
     2221 tggaacagat aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa
     2281 ataaaacaat ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta
     2341 ttgcatagac cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg
     2401 taaattatac caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa
     2461 gaaaaagact gaaatatgtg ataaacatct catacttcag tctttttcat taactattca
     2521 taagacatta ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga
     2581 ctaacagcca gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg
     2641 gtcagactac caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca
     2701 ccagcagctg caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg
     2761 taaacagttg gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc
     2821 gaacgggttt ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca
     2881 aaattggctg ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg
     2941 atcatgacag ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca
     3001 gcgatgattg cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct
     3061 aaaccttcgc caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg
     3121 ataactaatg aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg
     3181 aggaattttt caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac
     3241 gtatactgca tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct
     3301 gaaagtaaag aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat
     3361 ccattcactt taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag
     3421 acggcattcg acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca
     3481 atcgtagtcg ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg
     3541 atcggcgtaa agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct
     3601 ttcggagctg aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga
     3661 tccatgatta tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc
     3721 tgttttaatt tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc
     3781 gcacatggaa ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga
     3841 atctgctcgg acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc
     3901 cactcactaa tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac
     3961 agttattcaa ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta
     4021 acaataattt gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt
     4081 caatcgattg tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa
     4141 gaccgtttga gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat
     4201 ccccgatact taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat
     4261 tgattacttt tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg
     4321 attgttctaa agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa
     4381 cagaagaggc tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa
     4441 gtgtgctgct taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca
     4501 ctttaaaagc agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc
     4561 ctagtgtaat gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca
     4621 aactgttatg atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta
     4681 taatgatatc tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat
     4741 tcaggatcgt tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta
     4801 agctactttc aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta
     4861 ggacttcttg ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc
     4921 ctgctgcgtc taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc
     4981 cagatgtatc gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag
     5041 ccccaacgcc tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt
     5101 tggcaccttt acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct
     5161 tgggcatgtt ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg
     5221 tgttcatttt acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa
     5281 acgttttagt aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt
     5341 caagggtgca gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc
     5401 tttttctggg aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa
     5461 gattggttgt gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc
     5521 atagccaata atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata
     5581 taatccaaaa gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag
     5641 ttctgctgtg atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg
     5701 gtcgtgaggg atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac
     5761 attttccggt ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa
     5821 gtgcatgccc gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc
     5881 ttcagatttt ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt
     5941 gattgcatct gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt
     6001 gagctcggct agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt
     6061 gacgaaattc tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg
     6121 attcgtgata tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct
     6181 agcaaaatag tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt
     6241 tttcggactg aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac
     6301 gccggaaagt ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct
     6361 atctaaatcc tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt
     6421 gccagtactt atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt
     6481 gcagttttcg gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg
     6541 caagcatctt cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca
     6601 tatacaccgt ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga
     6661 agttgaagat caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac
     6721 atattatctg tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca
     6781 gaagcagtca ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct
     6841 acgttcacta aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg
     6901 tttgtcagaa tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt
     6961 tgcatgtcga tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa
     7021 tcattcatga tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc
     7081 gtttatttgt caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa
     7141 aataaataag tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
     7201 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
     7261 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
     7321 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
     7381 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
     7441 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
     7501 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
     7561 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
     7621 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
     7681 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
     7741 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
     7801 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
     7861 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
     7921 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
     7981 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
     8041 aactgctgga cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc
     8101 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
     8161 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa
     8221 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
     8281 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
     8341 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
     8401 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
     8461 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
     8521 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
     8581 caaagcttac aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga
     8641 tcgacccgaa gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc
     8701 acagcaaaaa atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga
     8761 tgctaaaaaa cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg
     8821 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
     8881 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
     8941 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
     9001 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
     9061 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
     9121 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
     9181 aaaatatgca atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt
     9241 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
     9301 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
     9361 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
     9421 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
     9481 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
     9541 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
     9601 cgtgggattg aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga
     9661 ctatcaagca atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga
     9721 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
     9781 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
     9841 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
     9901 aacaggaatc gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca
     9961 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    10021 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    10081 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    10141 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    10201 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    10261 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    10321 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    10381 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    10441 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    10501 tccattagtg atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac
    10561 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    10621 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga
    10681 aacaaacggc aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag
    10741 ctgattgaac accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa
    10801 tactcaaata aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa
    10861 aagcttttga acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga
    10921 tagacaaata catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat
    10981 aaagataaat tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat
    11041 ataagttgtg gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga
    11101 caaagtcatt taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg
    11161 agatttaaaa ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat
    11221 ttggctaaac cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta
    11281 cacagccatc gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc
    11341 aaagaaatac cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca
    11401 tgaatggttc aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag
    11461 agaagagcca acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga
    11521 tacggggaaa tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa
    11581 ccaagcagta agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa
    11641 aggattccgt ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa
    11701 agaaaatgat ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga
    11761 attgaaccaa gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc
    11821 tacgacgatc gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt
    11881 ctttaatttc catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc
    11941 atttgatttt gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg
    12001 taacggctgg aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt
    12061 tgtagctatc gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt
    12121 gaaccgtggg acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta
    12181 ttcatcgatt tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga
    12241 acaaggattc acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc
    12301 tcgaacaccc atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg
    12361 gttaaaagtt ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga
    12421 ttctattttg tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc
    12481 acaaggagat tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca
    12541 atttgaagga cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc
    12601 catcccagaa ggattcacag aagccaatat tcttatcgat aattattccg atactgttct
    12661 tcatcaaagt ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa
    12721 aaacacaaaa cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt
    12781 aaaataatct tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt
    12841 attgtagcgt tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata
    12901 gataggaata ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac
    12961 gattaagatc gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa
    13021 gtcaccgtgg agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt
    13081 agagtcttgg aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg
    13141 aatgatacat aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag
    13201 taagaaacaa acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag
    13261 aaatgaaccc aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc
    13321 tggtgggaca atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa
    13381 agcgacaatt ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt
    13441 gctgatccgt tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt
    13501 cacgtcgtca atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa
    13561 aaattgtcgg agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt
    13621 ctttgcctgt tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa
    13681 aataatcaca taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt
    13741 gatgactggt tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt
    13801 agcgataatg attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat
    13861 cagcgcaagt aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg
    13921 gatcaaacga ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac
    13981 ttcattatag acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc
    14041 gtcaatcatt catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt
    14101 taaccatatg ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc
    14161 gaatcggaac attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga
    14221 taggtatatt ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga
    14281 aagccgagga cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt
    14341 ttacaaaagc aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg
    14401 attcccacga ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct
    14461 ttgtttataa tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag
    14521 aaggcaatgt ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag
    14581 aaggacatga tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac
    14641 atgtatggct agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga
    14701 ttgaagctta cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga
    14761 aacttcaagc actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt
    14821 ttgtcacgca acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat
    14881 cgattgctgg tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac
    14941 actttgttaa agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta
    15001 ttgccagaac gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag
    15061 gattgacgaa tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc
    15121 tcgaagcgtt gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca
    15181 aaaaagaaaa gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc
    15241 tttcagattg ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg
    15301 atcctgtttt tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag
    15361 aatattatac gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga
    15421 tggcatttac gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag
    15481 aaatcttgac ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata
    15541 aggaaagtgg cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact
    15601 ccgaacattt tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg
    15661 agaattggcc aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc
    15721 ttttgcactg ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt
    15781 ccaaactatt cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga
    15841 tggtctcgcc gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt
    15901 gtgtattgat aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt
    15961 ctttgatctt ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg
    16021 gcgctcctag cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat
    16081 cattaaactc tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa
    16141 ttttgctcag gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat
    16201 aatcagtcgg ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca
    16261 catagattat ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat
    16321 ccatttcact gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga
    16381 tcttggctgc attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta
    16441 agttttcaat catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat
    16501 cgtcttcaca aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa
    16561 tcgtttgaga aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct
    16621 ttgtcaattc atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg
    16681 agaacccttt ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac
    16741 gaatcatcac ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag
    16801 cactagctcc ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg
    16861 tatgtttcgt atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt
    16921 cctgtgccat catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat
    16981 ccaacatact tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt
    17041 gatcataata agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa
    17101 aaagcagatt ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat
    17161 ctttgatata atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct
    17221 tattagagat tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga
    17281 aaaaactcgt attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa
    17341 taatgatata gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca
    17401 cagtgtgaaa ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa
    17461 aagcggataa gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt
    17521 tcaaaacaaa aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc
    17581 caaaaggaag cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca
    17641 tcagcattcc tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa
    17701 tcaaaataca agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt
    17761 caatcaataa gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca
    17821 taaagtacag ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt
    17881 aatttttcag ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag
    17941 tcagataagt tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt
    18001 catcaagtag tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa
    18061 ataggtagaa aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat
    18121 gctgatcgcc ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt
    18181 acctcttgat ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat
    18241 tgggaaggag atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag
    18301 tagtgtccac agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg
    18361 gatgcagata taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga
    18421 aaagactaga acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt
    18481 tacttggaca tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa
    18541 tttgttcaca actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa
    18601 aaaataaaaa acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc
    18661 tcctaaaaaa atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga
    18721 aaagtacttt ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga
    18781 ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga
    18841 aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat
    18901 ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc
    18961 tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca
    19021 gataaaatgt tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg
    19081 aataatgtta aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg
    19141 gcaggagaat actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta
    19201 ttttcatgaa taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat
    19261 aaagtcaagg cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca
    19321 ggaaggatgc cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca
    19381 ctaactgaaa tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat
    19441 aatgaagtat tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt
    19501 ttctttttga acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta
    19561 ctagaccgct ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt
    19621 gtttctgaag tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta
    19681 gaagaaattt cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa
    19741 actatgttag cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct
    19801 gaactctatt cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt
    19861 gatatatgtc ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca
    19921 tgtggagaac aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca
    19981 gatgcccagt cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact
    20041 aaataatata aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct
    20101 tgcttagttt ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc
    20161 cataaatgaa atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc
    20221 gaatgggcgc caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca
    20281 agaacgacac ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa
    20341 taatcatata agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag
    20401 gcacgcccgt tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa
    20461 atcgttacta atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact
    20521 gcttcataat atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca
    20581 attagatact ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta
    20641 ccaacactta gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt
    20701 tgagcagagg caaaagcacc atattggata taagtataac tgtccatggc tcctccgata
    20761 aatgtcagca aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc
    20821 accttttatg aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa
    20881 attttcagaa aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt
    20941 ataaagaaaa aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag
    21001 aagaaagatg ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa
    21061 gaattgaaac gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa
    21121 gaaatcattg ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa
    21181 gtacaagtaa aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc
    21241 tataatcgct tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt
    21301 cgaatcatag caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat
    21361 ctgatgacgc aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac
    21421 gctgcaaatg aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat
    21481 atcggaacat tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct
    21541 gaagtagcaa tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat
    21601 gctgttttgc aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa
    21661 aaaacgattg cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg
    21721 gttcagttag ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca
    21781 gaacgactgt atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta
    21841 gagttcaatg atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat
    21901 tatatcggcc aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt
    21961 caatgggaaa tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga
    22021 gatgatgatc agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt
    22081 gaaaaagaat atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct
    22141 attgtccaag gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg
    22201 atgattccag cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa
    22261 gcagaaagtc agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat
    22321 aaggaatcaa tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg
    22381 ctgaaaacga atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt
    22441 atcaagtctt tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg
    22501 caaaagaaaa atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg
    22561 aaaaaaagtg aatgcgatca atacttttct cctaaatatc aaaatatagc cgttgcagat
    22621 tatattttgt cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag
    22681 gaagcgttgc gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt
    22741 catctgccac gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa
    22801 gtaaagcagc atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca
    22861 gctaaagaat taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt
    22921 atccagagca ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt
    22981 aacgaaggaa gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa
    23041 ataaaagcag aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg
    23101 actagagcaa gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg
    23161 aaagtatcga gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag
    23221 agagggtgtg acagaagtgg tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt
    23281 ctcaaatttt tgtgaaattt cagcttattt tcgaagaagc tatttctgga acacagttta
    23341 ttc
//
LOCUS       DADVXB010000032        23341 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.032, whole genome shotgun sequence.
ACCESSION   DADVXB010000032 DADVXB010000000
VERSION     DADVXB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.032"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            19..1680
                     /locus_tag="KB902_000985"
     CDS             19..1680
                     /locus_tag="KB902_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6807827.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1750..2097)
                     /locus_tag="KB902_000986"
     CDS             complement(1750..2097)
                     /locus_tag="KB902_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBB6807828.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2181..3122
                     /locus_tag="KB902_000987"
     CDS             2181..3122
                     /locus_tag="KB902_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807829.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3123..4166
                     /locus_tag="KB902_000988"
     CDS             3123..4166
                     /locus_tag="KB902_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807830.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4172..5242
                     /locus_tag="KB902_000989"
     CDS             4172..5242
                     /locus_tag="KB902_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807831.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5232..6185
                     /locus_tag="KB902_000990"
     CDS             5232..6185
                     /locus_tag="KB902_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807832.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6197..7207
                     /locus_tag="KB902_000991"
     CDS             6197..7207
                     /locus_tag="KB902_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6807833.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7492..8313)
                     /locus_tag="KB902_000992"
     CDS             complement(7492..8313)
                     /locus_tag="KB902_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6807834.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8410..8688)
                     /locus_tag="KB902_000993"
     CDS             complement(8410..8688)
                     /locus_tag="KB902_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807835.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            8956..10965
                     /gene="metG"
                     /locus_tag="KB902_000994"
     CDS             8956..10965
                     /gene="metG"
                     /locus_tag="KB902_000994"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBB6807836.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11444..12031)
                     /locus_tag="KB902_000995"
     CDS             complement(11444..12031)
                     /locus_tag="KB902_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807837.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12206..13528
                     /locus_tag="KB902_000996"
     CDS             12206..13528
                     /locus_tag="KB902_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6807838.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13683..14459
                     /locus_tag="KB902_000997"
     CDS             13683..14459
                     /locus_tag="KB902_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6807839.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14452..15021
                     /gene="rnmV"
                     /locus_tag="KB902_000998"
     CDS             14452..15021
                     /gene="rnmV"
                     /locus_tag="KB902_000998"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBB6807840.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15014..15898
                     /gene="rsmA"
                     /locus_tag="KB902_000999"
     CDS             15014..15898
                     /gene="rsmA"
                     /locus_tag="KB902_000999"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBB6807841.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16349..16978
                     /locus_tag="KB902_001000"
     CDS             16349..16978
                     /locus_tag="KB902_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807842.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17102..18211)
                     /gene="ugpC"
                     /locus_tag="KB902_001001"
     CDS             complement(17102..18211)
                     /gene="ugpC"
                     /locus_tag="KB902_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBB6807843.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18420..18842
                     /gene="mgsA"
                     /locus_tag="KB902_001002"
     CDS             18420..18842
                     /gene="mgsA"
                     /locus_tag="KB902_001002"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBB6807844.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19165..19701
                     /locus_tag="KB902_001003"
     CDS             19165..19701
                     /locus_tag="KB902_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6807845.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19741..21504)
                     /locus_tag="KB902_001004"
     CDS             complement(19741..21504)
                     /locus_tag="KB902_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807846.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKNIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21507..23222)
                     /locus_tag="KB902_001005"
     CDS             complement(21507..23222)
                     /locus_tag="KB902_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6807847.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSIPEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7505 a         4282 c         4762 g         6792 t
ORIGIN      
        1 aataaagggg tacgtaaaat gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc
       61 cttgtacttg ctggatgtta tggcggcagt tcagccacaa gcagtagttc agcaaaaagc
      121 ggttcagcag atggaggagg cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct
      181 gacttatcag ttgcaacaga tacaatcagt tttacagcat tgaataacgt ttatgaagga
      241 atttaccgtc ttgatgaaga cagcaaacca cagccggcag gagctagcga gttggcagaa
      301 gtcagtgaag acggattaac ttacaaaatc aaattacgag aagacgcaaa atggtcaaat
      361 ggtgatcctg ttacagcagc ggattacgtt tatggctggc aacgaacagt agacccagct
      421 acagcttctg aatatgctta cctgtatgcg ccagttgaaa atgcagaaga cattacagct
      481 ggaaagaaag ataaatcaga actagggatc aaagcagttg gtgactatga attagaaatc
      541 aaattgacga aacaaacacc atatttccaa tatctgcttg ctttcccatc atttttccca
      601 caaaaacaat ccgtagtgga agaaaatggg gatgcctatg catctgcaag tgataaagct
      661 gtttataatg gaccattcac attagaagat tttgatggac caggaacaga tacagaatgg
      721 acttataaga aaaatgatca ttactgggac aaagatacag taaaactttc tgaaatcaaa
      781 gtcagtgtag taaaagaatc ttctactgca ttgaacttat tcaaagatgg ccaagcagat
      841 gacgtgatct tgtctggtga gttagcacag caaaacgcaa acgatccagc ttatacttct
      901 gttaaagaag cgcggacaag ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc
      961 aacaatgtga acctaagaaa agctatttct tattctatcg atcgtgaagc tttagtaaaa
     1021 caagtactag gtgacggatc agttgtctct acaggattga tcccatcaga tatggtaaaa
     1081 agtccaacaa cgaacgaaga ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa
     1141 gataaagcaa aagaatattg ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa
     1201 tttgatttga tggcttctga tgatgattca tcgaaaaaag taatcgaata tgttcaaaac
     1261 tcaatccaag aaaacttgga tggcgtaaca gtcaaaccaa cacctgttcc attctctgta
     1321 cgtcttgacc gctcaacttc gggtgatttt gacgcagtac taggcggatg ggctgctgac
     1381 tatgcagacc caagcagctt tactgatttg tttgtcacag gtaattcata caaccgtggt
     1441 cgctggagca atgcagaata tgacgaagca gttaaagcag cttcatcaac agacgctggc
     1501 gatgaacaag cccgttggga tgatttccaa aaagcaatca agatcatctc tgatgatatg
     1561 ggtgtcgttc cggtgtacca aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt
     1621 atcgttcacc atgcggcagg cgcttcatgg gattacaaat ggacatacgt tgaagaataa
     1681 tcgttaatac cgtgagcatg agaaaaaacg aggctgcggc aaatgtcgca acctcgttct
     1741 catattcact tatcctaaca aagaaaaaag catgaaaata gcagaaagag caattagtat
     1801 tccggcaatg atcagccaaa agctgtacat accgtagctg gcagacgaga gcgaggaaaa
     1861 ttctggtttt ttctttcggt tccttgttcg tgcaagatgg accgatcgct gaaaatgatc
     1921 gaagaaaccc gaagaaaaga cccataaaaa accgccgata atcagaaacg gcaatgacca
     1981 taagaataga tcattagata attgaatgag tgtaaaggaa tggttgatga gattttttat
     2041 taaaataacc agaatcagta gaaaagctac tgcgtagggg atagattttt ttttcatttg
     2101 attgctcctt tatttttggt tcattatcta ataatgtagc gaaacatctg tcagaagtca
     2161 aaagctaggg ggaaacatta gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt
     2221 tcatgatcat cacgctttgg ttaattgcaa caatcacctt tttcttgatg caattgctgc
     2281 cgggcacgcc atatacgaat caggaacgtt tgagtcctga aacaatcgag atgctaaata
     2341 aacaagtcgg tttggataaa ccagttatcg tacaatatgg gatttatctt tctaatttgc
     2401 ttcaaggaga ttttggaatt tccttccaat ttaaaaacca gccagtcgca catttgttag
     2461 ctggaagaat cggaccatcc ttgcagttag ggttacaggc aattatcttt ggaacagtcc
     2521 tagggacgat tttaggaacg atctctgcca tgaagcaaaa tacatgggca gatacatctt
     2581 ctacactcgt agcgatatta ggtcgttcca ttccaaactt tgtatttgct gttttattac
     2641 aatatatctt tgcaatcaaa ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt
     2701 acacaatctt accaacaatt gcgttggcca tgtcgccgct tgctgactct gctcggttta
     2761 tccgtacgga aatggtggaa gtactgcata gtgattatgt ggaattagca aaagcaaaag
     2821 gattgagccg ttgggaaatc gcctttaaac atggtcttcg aaatagtttg attccattga
     2881 tgactttatt aggaccgtta gctgtagcat tgatgaccgg atcactggtg gtagaaaata
     2941 tctttgctat tcctggtatc ggggaacaat tcgttaagtc aatcacaaca aatgattatc
     3001 ctacgatcat ggctgtaacg atcctttact catttatgct gatttttgtt attttgatcg
     3061 tggatctatt gtacggtcta gttgatccaa gaattcgtgt ttcagaaggg agccgaggat
     3121 aaatggaaat gataccaaag cgttatgaaa cagttgcaga tatccctgcg gatgaatttc
     3181 ttccattaca aaaaaatacc gaagaagaac gtgaacagat tactgcacct tctttgaatt
     3241 ttatccaaga ttcatggcgc cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt
     3301 tactattggt catcattttg atctctgtga tcacaatctt tgtttctcct catgatccaa
     3361 ctgcccaaaa cgtggcttat atcaatttgc ctcctcgtat tccgggaatc aatatcgatg
     3421 gattgaatgg aaaagcaatg gttggtggtg aacttgttga taaatatgct caagcaaacg
     3481 tcccttcaaa cgtaaatttc tttttaggaa cagacggttt gggacgtgat gtattaagcc
     3541 gcttatttat gggaatgaga atctcgttgc tgatcgcatt tattgctgca ttactagatg
     3601 taacgattgg tgtagcttac gggttggttt ctggtttgtt aggcggacgt gtcgataacg
     3661 tgatgcaacg ttttttggaa atcttatcag gaattccaaa cctcgttgtc atgattttga
     3721 tgttggtcgt ttttgaacca ggaatttttt caatcgtggc tgctatggcc atcacaaact
     3781 ggataccaat ggcacgtatc gttcgtgcac aaacaatgaa attaaaagat caagaatatg
     3841 ttttagctgg attgacatta ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc
     3901 cgaatatctc tagtgtcatt attattcaaa tgatgtttag tattccatct gctattttct
     3961 tcgaagcctt tttaagcttt atcggtttag gtcttacgcc tccgtcagct tcattaggaa
     4021 cgatgttgag cgaagggtac aagacattcc tgtatctgcc ttatctatta tggattccgg
     4081 cagtaacttt atcggttatc atgattggct ttaacttact tgctgatgga ttgcgtgatg
     4141 cctttgatcc taaaatgaaa gagtgaagac gatgacgaaa attttagaag tgaaagactt
     4201 agaaatctct tttgatacgt atgctggaaa ggtacgagcg attcgcggtg tcaattttca
     4261 tttgaataaa ggagaaacat tggcgatcgt tggggaatct ggaagtggaa aatcagtgac
     4321 gaccagaagc atcatgcgct tgctgtcaag caacgccaat atagatgctg gtcaaatcct
     4381 ctttaaaggt aacgatatcg ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa
     4441 agaaatagcg atgattttcc aagatccaat gacctcttta gatccgacga tgcccattgg
     4501 gaagcaagtc gctgagtccc ttagaaagca taataaagtt tcaaaaaaag agggacaaaa
     4561 agctgcatta gaattgctta aattagttgg aatacccgaa gctgagaaac gtatcaacag
     4621 ttatccgcat cagttctcag gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt
     4681 atgttatccg gaaatcctga ttgctgatga acctacaaca gcgcttgatg tgactattca
     4741 agcacagatt ttggagctgc tgaaagaaat tcagacaaaa atcgatacat caattatctt
     4801 tatcactcat gaccttggtg tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg
     4861 aggaagaatc gttgaagttg gaacatcgga agaaattttc tacaacccgc aacatcccta
     4921 tacttgggga ctgcttggtt caatgccgac attagatagt gcgaacgatc gattgtatgc
     4981 tattcctggt tctccaccgg atttattgaa cccgccaaaa ggagacgcat tctatccaag
     5041 aaatgaattc gcgatgaaaa tcgatgcaga acaagaacca ccattttttg aactatcaaa
     5101 aacacacaag gcagcaactt ggctacttgc tccgcaggca cccaaagtga caccgccaga
     5161 agaaatccaa cgtcgctggg ctatctttaa agagaaacaa aaacatactt acggtcaagg
     5221 aggaattgct gatgccaaat aaactacttg aagttaaagg attgaaacag tatttcaatg
     5281 taggaaaaaa gaatgaagta catgctgtaa atgacatcag ctttcacatt tatgaaggag
     5341 aaacattcgg tttagttgga gaatctggaa gcggaaaatc cactactggc cgtacgatca
     5401 ttcgcttgaa tgaacctact gatggtgaga tattattcga cggtcaagat ataacgaaga
     5461 tcaaagataa aaaaggtttg acgaaattcc ggcatgatgt tcagatgatc tttcaagatc
     5521 catacgcttc gttgaatcct cgtatgaaag tcagagatat cattgccgaa ggaattgatg
     5581 ttaatggact agctaaatca tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa
     5641 ctgttggatt gaatccaagc cacggtactc gttatcctca tgaattttca ggtgggcaac
     5701 gccagcgtat tggtattgca cgagcattgg cagtaaaacc gcgttttatc atttgtgatg
     5761 aaccaatttc tgcactagat gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc
     5821 tccaaaaaga acatcaattg acctatctat ttattgcaca tgatttgtcg atggttaaac
     5881 atattagtga ccgaatcggt gtaatgcata acggcttgtt attagagatg ggaacaagtg
     5941 atgaaatcta taatcacggt gttcatcctt atacagaaag tttgttatct gctattcctc
     6001 taccagatcc agaccatgag agaaaacgca gaagaatcaa atatcaacct gaaccagatg
     6061 acggacaagt acgtcaactt cgtgaaatcg caccagaaca ttttgtctat gcaactgagc
     6121 aggaagtccc atattacgca aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta
     6181 actaggaggg acatagatgc taaaagcttt taaattccgt atgtatccga cagaagaaca
     6241 aaaacagcaa ttgattcgta cttttggatg tgctcgattt acctataacc atttgctgaa
     6301 aaagcggcag aaaagttggc aacaaacagg agtagccaat ttttcgctca cacccgctac
     6361 attaaaaaaa gaatacccat tcttaaaaga agtagacagt cttgctttag caaatgcaca
     6421 gcttaatttg gatcgggctt ttcgcaatta tttcaaggga cgtgccagct tcccaaagct
     6481 taaaacgaaa aaaagtatgt ggcaatctta tacgaccaac aaccaaaccc gtacgatcta
     6541 tctggaaaat ggctacttaa agttaccaaa acaaaaagaa ctaatcaaga taaatcagca
     6601 tcggccagtt gaaggatcga ttcgctccgc tacgatttct gctcgatata atgaagaatt
     6661 ttatgtcgca ctactttgtg atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat
     6721 cgggatcgcc tatcatccga agacattgat ccaaacatct cgacctctag aagtaacttt
     6781 accaaaattt caccagacag aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa
     6841 agtccgctcc gctcaccata gaaagatcag gttagatcag gcaagcaatt atcagaaaca
     6901 aaagagaaaa gtaatggatc tttatctgaa acaaaagaac cagcgagaag attatcttga
     6961 acaattatct gggaaattgg tcaaacaata tgactactta tttgtagaat cttttccaaa
     7021 agaagaggca catgctgatt tttctattca cgactggcat aaattaataa caaaattgcg
     7081 ttataagtcc caatggtata ataaaaaatt tcttttgatc aataccgacg gagcagaaga
     7141 aagcaattcc gtaagaaaga gccaagtagt agaaaaaatg ggcagacatt cggttatcaa
     7201 gggataaaaa atgaatgaaa ctgataggag cgttagggtt agccttgtta ataaaaagtc
     7261 ttaatgactt ttgtttctag gaatttttct tttgaagaaa agctcactaa ttatgacaaa
     7321 ccaataaaac aatagcagaa aaagttcgta cgagcttttt ctgctattgt taatttttta
     7381 ttcagaaagt ttacgaatac atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt
     7441 gtttttgcgt tttttcttga atgattaggt ctgaatcttt tgctcacaac cttattcatg
     7501 gtgccccggc ttgagctgat agatttttga aggacggccg attcctacag gacgttcacc
     7561 gatctcatcg aaatattgga gcatagcttt cttaaaattg gaatgatcga tcgttttata
     7621 atcgatccct aagaatttag caaatacttt tcgagcttcc gtaatcgtga aatctttacc
     7681 taaaacttgt agaacttgcg gctcgtgttc cattttattg actacacggt tgaatgcttt
     7741 caagatgatt tgactatggt caaaagccaa agtatctttg ccagaagact ctccagtgac
     7801 taaatcaagc gagatagcca cttctccgct agataaatgg atcttgttac tatgacgttc
     7861 tagtgtgaac cagcgtactt ccttggcatc atctccggcg attagcggtt cttctccaat
     7921 aaaggctaag tagctgactg tgacgaccca gcctcgcgga tctcgattag gcgtactgaa
     7981 tgtatgcagt tgctcaatat tttcttttga aataaccaca ccagtttctt cctttgtttc
     8041 tcttaagacg ctttctccag ttgactcatc cttttggaca aagccaccag gcaatgccca
     8101 tgaatttcga taaggatgcc cttttctttg gatcaacaaa actttcagct gatcttcttc
     8161 tttgttatag cacatcagta cgatatcgac agtcaaagag ggcttgtcat attctggacg
     8221 ttcctgtttt tgataccagt taagaaattc ttcttcactt gctttatgtt cataatataa
     8281 tttttcttct tctttagaag caaaacggtt catctgacca cctccattga cagtaaaagt
     8341 actttttacc ttattgtagc agactctgaa aaaaaaccaa ggatttactt gaaaaatcta
     8401 ggttatcatt taaatatgaa aaataaatgg aagtatgaga ttgaataaaa agaaaagcag
     8461 ataaaacggc aatactttat accgctcttc acgaatggca aagaagccac aaataacgat
     8521 atatacgtca atgataaaac gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc
     8581 atggaggtta aaataaccat acatacgaat ataaaaatag ctgaatatta aatgtgctaa
     8641 tgaaagaaaa gcaatactaa gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt
     8701 cccttactaa gatagatagt ctttattata ccacgtgtga ggggagaaat aaaaagccgt
     8761 tttttagtag atatgaaaca aaacaaaaac ccgcatttat tcaacctatt catcctttta
     8821 aaggatagat tgaacgtaga tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag
     8881 ctaacagcat gcttttttta tggtatacta gcaaggaaac gaattcgcat catgcgataa
     8941 aggaggaaga gccccgtggc agaaaaggaa actttttata tcactacgcc aatctattat
     9001 ccaagcggca aacttcatat cggcaactcg tatactacga ttgcatgtga cgcaattgct
     9061 cgttataaac ggttgatggg ctttgatgtg ttttatctca ctggagtgga tgaacatggt
     9121 caaaaaatcg aaacaaaagc agaagaacta ggtgtaaaac cgcaagaata tgtagataaa
     9181 atggcggctg atgtcaagaa attatggaaa acgcttgata tcagttatga taaattcatt
     9241 cgcacgacag atgattacca taaagcagct gttcaaaaaa tatttgatcg tttattagaa
     9301 cagggagata tttacttagg tgaatatgaa ggctggtact ctgtttctga cgaagaattc
     9361 tttacagaaa cacaacttgc agaagtgtac aaagatgacg aaggtaacgt gatcggtggt
     9421 aaagcgccaa gtggacacga agtagaattg gtaaaagaag aatcatactt cttccgcatg
     9481 agcaaatacg cagaccgtct attggaatac tatgaagaac atcccgaatt catccagcca
     9541 gaatctcgta aaaacgaaat gatcaacaac tttatcaaac caggattaga ggatcttgca
     9601 gtttcacgaa caacttttac ttggggagta ccagtcaaga gtgatccgaa acatgtggtg
     9661 tatgtatgga tcgatgcatt atccaattat attactgcac taggatatgg ctccgaagat
     9721 gaaagtctat tcgaaaaata ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt
     9781 cgctttcata cgatctattg gccaatcatg ctgatggccc ttgatttgcc tctacctaaa
     9841 aaagtatttg ggcatggctg gctattgatg aaagacggaa aaatgtctaa atcaaaagga
     9901 aatgtcgttt atcctgaaat gcttgtggaa cgttatggtt tagatgcact ccgttattat
     9961 ttgcttcgtg ctgttccgtt tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc
    10021 cgtgtcaatt atgatctggc aaatgatcta gggaacttat tgaatcgaac gattgctatg
    10081 atcaacaaat attgtgatgg actcgttcct gactatgcct cacttgtcac tccatttgat
    10141 agtgaactgt ctacgacggc tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa
    10201 atggaattca atacagcatt ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac
    10261 attgatgaaa cagaaccatg ggtattagca aaagacgaag aaaagaaagc tgaattgaat
    10321 agtgtcatga tccatttagc tgaatctttg cgtatcgcag cgatattact tcagccaatc
    10381 atgacagaaa cgccagagaa gatcttcaat caactaggat tggactctga aacaatgaat
    10441 cttgaaggat tacactttgg cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca
    10501 ccaatcttcc cacgtttaga tatggaagaa gaagttgctt ttattcaaga aaaaatgtct
    10561 gaaggtactc aaacaaacga agatacagtc aaatgggatc cagaagaaac agaacttgtt
    10621 tcaacgaaag aaaaacaaat caaatttgat gtatttgaaa aagtagaact aaaagtagca
    10681 gaagtcatca actgtcaaaa agtagaaggg gcagataagt tgctgcaatt ccgactagat
    10741 gctggagaca gccaagaccg tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca
    10801 agcgaattga tcgggaaaaa agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt
    10861 ggacaaatca gtcaaggaat gatcctttct gcagaagcac cagatggctc tttacaagta
    10921 atcgaagcac caaaatccat gccaaatggc tcagaaatcg catagaaatt caaagggggt
    10981 atgacactag ttgtgtcata cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt
    11041 ccttcttatt acttgaagcc aatcatataa tacagaaaca gagaactatc caaaataaat
    11101 cctagaaaaa gaagtacgag cttcgctgat ttttgttaat ttagaataat actaatagga
    11161 atcgtaaaaa cagaaaaaaa gcataatgat aaagggtcgg gcagatttta attgattcat
    11221 ctggtactct tttttattgt ccttacattc ataaagtttg aatgcaatga ctttattaca
    11281 tctatattta tatctaacag tagcgttgat gtgttaatta taagttctat cactttatgt
    11341 tcaattagtt tgtgctctta tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg
    11401 ctttgacttc gatgattgtt ttctttattt tgtaaaaatc ctatcacttg attttatggt
    11461 aaccttttat ttttgtcttc aaacggcttg gtaagagagc agtaagcagt gcaaatggga
    11521 tcgaaaagac ataccagaaa atcgtacgtc cgataccata atgttgatag agctttgtca
    11581 acatcacgtg taacaagatc aaccctaaaa gcaaggagcc agctataaac caatgattat
    11641 cccaatgcat gacttcacta agtgccatca ctccaaaagg atagaaataa aaatagatcc
    11701 cgactaaggt catccgccag ttctttgtaa atgttccgat attcaataaa aagaaaatcg
    11761 ctgaaagcaa aataccgata ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc
    11821 acaagatcat cacaggacct ttgatcaatg caacgattgc gatgaacaaa gtcagcaata
    11881 ttagtttttg tgataacgtt gcaacagtca ttaatccaaa taaaattaat gtgaaccaat
    11941 gccaatggga ctgctgttgt tctttacggg aaaaatcgac ccggttggat aaataatctg
    12001 ctaatttcgg ataagaacgc ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag
    12061 gtttagtata cgaaaaataa aaaagaaata catccgtctt aagagggagt ttttcactga
    12121 aagtggagaa aaaagaatgg taaattaaaa tattctcagt tatactgaaa attataccaa
    12181 atttcaaaga agaaagagga tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt
    12241 tggcgcatta gctaccgtta tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc
    12301 tgctgttact gctagtactc agtctacaag tttgacattg ctagcttggc ttttgggtgg
    12361 tttcttaacg atctgtgctg gattgacagt ggctgaatta gctacagcaa tcccggaaac
    12421 tggtggagct gtaaaatata ttgaagctgc gtatggaaaa ttgcccagct ttttattagg
    12481 atgggcgcaa agcttgattt actttcctgc taatattgct gcattatcga ttatctttgc
    12541 gacacaattg acgaacttat tacaattatc taccgattat cttttgttga ttgcagtgat
    12601 caccgctgtt tctgtgacag ggttgaattt gttagggaca aaagtcggtg cttctgtaca
    12661 atcagtgacg ttgattgtta aattaatacc aattgctgtg attgtcatat ggggattatt
    12721 gaccccagga caaggaactg tccagttatt tccaatcgaa gctggaaaag atgttacttt
    12781 tgtcgaagga ttgagcagtg cgttgttagc aacgttgttt gcttatgacg gctggttagg
    12841 tgtcggtgca atggcagggg aaatgaaacg gccggaaaaa gatttgccta aagcaattat
    12901 tcttggtttg agttttgtaa cagtcgttta tctattgatc aattttgttt ttttgaaaac
    12961 tttgccgatt gatcatcttg ccggtaattt gaatgcagct tctgaagcat cagacgtcat
    13021 ttttggagga atcggtggaa agctggtcac tattgggatc ttgatctcgg tatacggtgc
    13081 attgaacggt tatacactaa ctgggatccg cgtgccttat gcgatggctt tagaagacga
    13141 gctacctttc agtaaacagc tgacaaagct ttcaaagaag tttacggttc cttatgttcc
    13201 tgcggttttc cagttagcag tagcttgtat tatgatgagc cttggttctt tcgacttttt
    13261 aacagacatg ttgatttttg tgatgtggct attcagttta ctgattttta tcggtgtctt
    13321 tattttaaga aaaaaagcgc cggaattgcc acgtccatat aaagtaccac tttatccaat
    13381 cgttccgatt attgcgattc tcggtgctat tttcatttta ggtatgacga tgatgacgca
    13441 aacgaaatta gcattgatcg gtataggtgt taccttgata ggtatcccag tctattatca
    13501 aaaaaagaaa aaacgctcag aagagtaaaa tatttcaaca acagacagaa aaagtacgaa
    13561 ctaggtcctc tagatcttcg tgctttttct atttcaataa aacaagttct tctattttga
    13621 tttttgctac ttctgcaagt agtgcttatg tgctaaagta agaatgaaaa ggagagataa
    13681 acatgatatt tgattctcat acccatttaa atgctgaaca gttcaatgaa gatattccag
    13741 aaacgattca gcgagcacaa gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata
    13801 cgccaacgat tgaaaagtct ttgcaattaa gccatgacta tccaaatata tacagtatta
    13861 tcggctggca tccgacagag gctggcagtt atacgaaaga aatcgaaaat aaattacaag
    13921 aacaattgac tttaccaaag gttgtagcat taggggaaat tggcttggat tatcattgga
    13981 tggaagaccc gaaagaagtc caagataaag tatttcgcag acagattgct atcgcaaaag
    14041 aaatgaacct accaatcagt attcatacta gagaagcact tgaagacacg tatcaaatcc
    14101 taaaagaaga agatgttcga gatatcggtg gaatcatgca tagtttcagt ggtgattatg
    14161 aatgggcaaa acgatttctt gacttaggga tgcatatttc atttagcggt gtcgtcactt
    14221 tcaaaaaagc attagacgtc caagaggctg cagcaaatgt accaatcgaa cgattacttg
    14281 tggaaacaga tgccccttat ctggcaccag ttccttttag aggaaagcga aatgaaccag
    14341 gctatactcg ttatacagta gaaaagattg ctgaacttcg gaatcttccg acagaagaag
    14401 tggctgccca aacatggaca aatgcgcacc gattatttgg tctaagcgaa catggataag
    14461 atgaagatcc aagagattat agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa
    14521 gtagttgatg cagatacgat agaaacaata gggtctgcaa tcaatgaaga gatcctgatg
    14581 caaattgaac atgcccaaga gactcgtgga gtgatcgttt ttaccgatcc tgatttttca
    14641 ggagaaaaaa taagaaaaat cattatggaa gctgttcctc aggcaaaaca tgcttttttg
    14701 ccgcgcacac aagctaaacc aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat
    14761 gctgctattt tagaagcatt gaaaaaggtc gtgacgccag acatttccca aacggctgtt
    14821 tctgaaatca ctagacaaga ccttttagac tatggtttaa tagctggggc acaagcaaaa
    14881 gaaaaacgag aaaaactagg tgacgagttg cgcatcggtt acacgaacgg caaacaattg
    14941 gaaaaacgtt tgaagatgtt tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata
    15001 gtggaggaac aacatgagtg aatatcgtga aattgcgaca ccctctagaa caaaagagat
    15061 tttattgaaa catggttttt catttaaaaa aagtttagga caaaattttc tgactgaacc
    15121 aaatatttta aggaaaatcg tagaaactgc gcaaatagat gaacatacga acgtgatcga
    15181 agttggacca ggaatcggtg cattgacgga acaattagcc aagcatgcaa aacaagtcgt
    15241 agcatttgag atcgatgatc gtttgatccc tgtattggct gatacgatgc aaccctatga
    15301 caatgtgact attgtacatc aagatatttt aaagaccgat ttgtcaacag ctgttagaga
    15361 aacatttcat gaggagcttc cgttaaaagt cgtagcgaat ttaccttact atattacgac
    15421 accgatcatg atgcattttc ttgaatcaga tttggttgtg gatgaactag tcgtcatgat
    15481 gcaaaaagaa gtagctgatc gtatctctgc tgaaccagga acgaaagctt atggttcatt
    15541 atcgattgct gttcaatatt atatggaagc cagtttagca ttcatcgtac caaaaacagt
    15601 atttgtccct cagccaaatg tagattcagc gattttgaaa ctgacaagaa gagatatacc
    15661 ggcagtcgaa gtgacagacg aaaaagcatt tttccgattg acaaaagcgg catttcagca
    15721 aagaagaaaa acgctttgga ataacttgca gcattcgtat ggcaaagatg accagacaaa
    15781 agcatggtta gcaaaaagct tggaaacagc tggaatcgat ccaaaacgtc gtggggagac
    15841 tttgtcatta caagaattcg ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa
    15901 aaagaggttg tgacagaagt tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca
    15961 aacaaaaata gttcctcatg tttttcgttt gtttgggctt attaccgcag atgcaagctt
    16021 ttgaacaccg tttaagaaag aggttgtggg cctgccgttt aactctaagt cacaaggaac
    16081 aatttcaaaa aacagcttct catgtttttg agttagttgg tcttattact tgatgcaagc
    16141 ttttgaccac tattatgccg aacaaggaga tgtgacacaa attttgtcac atctcctatt
    16201 tttgtttctt gatcaaaaaa ttcttatact tgatactcac actcattttg tatggattta
    16261 gaaaagaata tgtgtcttga cagttattag taagtgagtt atactaagtc gacatttatg
    16321 tgtcaagaca tattaggaga gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat
    16381 ttctgcttta ttgattggga tgggggtcat tatcccaatg gtcatgccta aaatcatgat
    16441 tccaccagct tcctttactt tggcgtctca tgtgccatta tttattgcga tgttttttac
    16501 accaggagtt gcagtggctg ttgcgctagg tacgacattt ggtttctttt taacaacgcc
    16561 ggttatcatc gcattgcgag cattgtcaca tcttgtgttt gcgttgattg gggcttggta
    16621 cttgcaaaag catccgagta tcgttttaaa aaatggacag tttacttttg ctaattggcg
    16681 tttccaaggg ttcaattttg tgatcggtgt gattcattct ttagcagaaa tgctagtagt
    16741 cagcatcttt tactttattg gtaatatgcc tgaaacatat tattctcaag gatattttta
    16801 tacagtattc atcttgatgg ggattggtgg gcttatccac agtttagttg attataatat
    16861 tgcttatttt atagcaggaa cactcagcaa atattttgat atccccgtat ttacggcagc
    16921 aaaaaaagaa aatcggaaag agtcgattca agggtacgcg aagaaaacga catattagac
    16981 atgatctctc aaaaaaaaaa ctctcatcta gtaatggata ataaatcctc taagatgaga
    17041 gttttttgtc ctaaaaagag ctgcaccaac atcttctggc acagctctaa cagggggcaa
    17101 tttatggaag tttgatgact tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt
    17161 tgaaggcaag gtcgactatt tcgcctggtt tatggaaatc tcttgcatct acttttgaga
    17221 tgaactcagt agaaccagtt tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa
    17281 cgacaacttc tgatttcact acggcttcag gtgaagcttc aagggctact tgttcactgt
    17341 ggatgtcttc tggacgaata ccgaagataa cttcttttcc ttcataacct ttttcaacta
    17401 atactttgtt ttttccttca ggaatacgaa gcttaagccc atgtccatct gtgataacac
    17461 catttttcaa tgtcacatta aagaagttca tggcaggaga tccaataaag ccggcaacga
    17521 acatattgac gggtgtatca taaacttctt tcggtgtacc gatttgttgg ataaatccgt
    17581 ctttcatgat aacgattcgg tcagccatag tcattgcttc tgtctgatcg tgagtaacat
    17641 agatggtcgt tgtttcaaga cgctggtgaa gtttggcaat ctcagcacgc atggctacac
    17701 gtaatttagc atctaaattt gataatggct catccattaa gaagactttt gcatcccgaa
    17761 cgattgcccg tcccaatgcc acacgttggc gttgtccacc agataaagca gctggttttc
    17821 gtttcaagta ttctgtcaga cctaagatct ctgctgcatt gtccacacgt tttttgatgt
    17881 ctgctttatc atatttacgt aatttcaagc caaaagccat attatcaaaa acagtcatat
    17941 gaggatacaa tgcgtagttt tggaaaacca tggcaatatc acggtcttta ggtgccacgt
    18001 cattcatgac ttttccgccg atatttagtt ctccttcaga gatatcttcc agtcccgcga
    18061 tcattcgcaa agtagttgac tttccacaac cggaaggacc aacaaaaacg ataaattcac
    18121 ggtctttgat tgatagatta aaatcagtta cagaataatt ttctgcattg tcatattttt
    18181 tatatacgtt tttcagagcc atttctacca taatacgttc cacactttct tttttagttt
    18241 tattaactat ttaaagtata aatgaaagcg ttaactaact tcaatgtcat gttgaacaag
    18301 aattttttct tttttttgtc aatgtgctag ttttaagctt taataaatat ccataagaaa
    18361 taaaaactga tacactggag taaataagta tgttaacaat atcaaaagga gtgtctctta
    18421 tgaaaatcgc tttgatcgct catgaccgaa aaaaacctat gatggtgaaa ttagcaacag
    18481 cgtataaaac aatattggaa aaacatgaac tttttgctac cgggacgact gggcagagga
    18541 tcacggaagc aaccggcttg ccgatccatc ggtttaaatc cggaccgtta ggcggggatc
    18601 agcaaattgg agccatgatt tcggaggatc agttagattt ggtgattttt cttcgagacc
    18661 cgctggctgc acagccccat gaaccagatg taacagcact tatccgttta tctgatgtct
    18721 atgagattcc gttagctacg aatatcggaa cagctgaggt gctactaaga ggactggaag
    18781 ccggcttcct agattttcga agaatcgtcc atgaaataga caagcatcca ctttcatttt
    18841 gatggataag cgtatggaaa aataacgttt aatgttcgcc tatatgtagc tataaaagct
    18901 aaacaaactg ataatatgcg atataatacg aacgtattgg ataatataaa caataatatt
    18961 agtttttcgt atttgcagta aatgtgaaaa tatgctatag tttctgtggg aaaagatccc
    19021 aaaaataata cagagtagaa aataaagcgt taagtgctaa gaggatggga tgttgcctct
    19081 tggacgaagg acgtaatgtt cgcggtttta ttttcgcatt cgctgcatga tacgatgtag
    19141 cagctcttaa aggagatgct aaaaatgaag aaacaccggt tagacgcacg tatgattgct
    19201 attatgggct tattgattgc attgatggtc actttgtccc gactggtagc aatcgagacc
    19261 ccatttatta aaatcagtgt cacatttatt ccacaagtga tcatgggcat tctttttggt
    19321 cctttttggt cagggatagg cgcagtttta gctgatttag taggaatggc cctcttctcg
    19381 aaatctgcat tctttattgg atttacattg aatgcattta ttgaaggagc aatctacgga
    19441 ttctttttct atcgaaaaga gatcacttgg aaaaatgcca ttctggctac gcttagtgtc
    19501 acgctgatca tcaacttatt tttgacacca ttatggcttg cgttgatgta ccatgtgcca
    19561 ttgttcagct gggtcgtttg ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt
    19621 caatcaattg ccatttatta cgtaggacgt agtattcctt acaaaaaaat tttaagaagt
    19681 ttagcgatcc acgctaaata aaaaacaagc agtcttccca tcccagaaga ctgcttgttt
    19741 ttattgtgct gtgaattgtg cttgatagag ccgtcggtaa taaccatctt tttgaagcag
    19801 ctcatcatgg gtgcccattt cgacaatagc tccctgatcc atcactaata tctggtccgc
    19861 atttttgatt gtggacaggc gatgggcaat cacaaaactg gtttttcctt ccatcattgc
    19921 taagaaggct tgttggattt ttttctctgt caatgtatcg actgagctgg tagcttcatc
    19981 taagatcaac atagggggat tactgatcat cgttcgagca atcgtcaaca gttggcgttg
    20041 tccatctgat atctttaacc cttgaccgcc aatcttagta tctaattttt ccggcaaacg
    20101 ttctacaaat tcatacatat aagaggcttt tagggcatca ttgatttctg cgtcacttgc
    20161 ttccggattc ccaaaacgaa gattttctcg caatgtactg tcaaatagcc aagtatcttg
    20221 taacaccatt ccaaaacttt tacgtaatgt atcacgttgg atagagcgga tgtcatggtc
    20281 atcgactgta attgttcctt ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt
    20341 ggattttccg gcccctgttt ttcctactat agcaatggtt tgacctggat aagcagtaaa
    20401 attgaaatct tcgatcaaac gctgcttggg gtcataagaa aaagaaacat gatcaaaaga
    20461 gacttttcct ttgatatttt tgggttccaa ggcataggca tctggcaaat caggcttttc
    20521 ttctggctga tcgatcaaat caaatgctcg ttctagacca gaaaaagcgg tttgcagttg
    20581 tgtcgtgatt ccagaaagtt cgataaatgg tttagaaaac tgacttgagt agatcgtaaa
    20641 gctggaaatc acaccaacag tgattgacga accactcttc aatgccaata ggccgccaac
    20701 taaaccaatc gataaataag caaggtgatc tacaaaacga gaagacgggt ttgtcaagga
    20761 agaagaaaat tgtgcccgtt gtcctttttc atatagatca gcatttagca gttcaaattg
    20821 ctgttgacta gcttcttctt gctgaaaagc tttcacgatt ttctggttac cgattcgttc
    20881 ggtcacaaag cccgagatat ccccaataat cctttgctgt ctatcgaaat ttgtttgtga
    20941 agcacgagca acgatccaac tcacaaggaa aataattggt gtagaacaaa gaacgaccaa
    21001 tgtcagaagt ggacttagac gcatcataaa aataaacgaa agaatgatga ttgccactcc
    21061 agaaaataat tgattgaagg ccgcagaaat tgcaatggaa atattgtcca tatcatttgt
    21121 aaatcgactg acgatatttc cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt
    21181 cagatgagca aatgcatctt ttcttaattt tgcaacggat aagtaagcta accgattgct
    21241 taacacttgg atgagccatt gactgactac gttgattaaa acgataccac cgaatagaat
    21301 aagtaaatgg aacagtcgat tgaagcggac ctgtccttct ccaatcattt gatcgatact
    21361 ttgaccaatt tgtaacgtca tcacaactgt tgcaatccca ttgatgattc ctagtatcac
    21421 agctagccaa atgttttttg cataggcagt aaggtaagga atgaatcggc ggagcgtctg
    21481 caaggataat ttttttactt tcataactat tcttcctcct gtgatgcgac gatttcctga
    21541 tattctgctg attgagcaag taattcttca tgggtaccct gagcagcaat cttaccttga
    21601 tccatcacta agatatgatg tgcttcttga atagagcgga cacgttggga gataataatc
    21661 actgtactgc caagataagt ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc
    21721 aacgcactta aagagtcatc taaaatcagt aatgctggct tggcaatcaa agctcttgca
    21781 atcgtcagtc gctgtttttg tccgccagag aaatttttcc cattttccat gacttttgta
    21841 tctaaaccat ttggaagctg acggacaaat tcttctgcct gagcgatttt cagagcttcc
    21901 caacattctt tttctgtggc gtctttctta ccccattgaa ggttttcacg aatagtcccg
    21961 gtaaatagta cagaagtttg gggaacaaga gcaatttgct gacggagatg atccagctgc
    22021 caagaacgaa catccattcc gtccattata actgtaccgg aactgacatc atagaaacgc
    22081 ggaatcaatt gtgtcaaagt cgttttcccg cttccggttg gaccaatgat tccaaggact
    22141 gtatttcgct tcagctgaaa tgtaatattt tggagagaaa gaccagaatc aggagtataa
    22201 cggaagtcaa catggtcaaa agcgataatt gcttcagaag aaaaatcggg agtagtactg
    22261 acctcagctt caggaatcga attttctgtg tctagcacct ctttcacccg atttcctgaa
    22321 gcttcggcac gtgtgaagat cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt
    22381 tgattcatat aattgatcaa agcaagaact tgtccttgtt gcaagctacc aatatttact
    22441 ttgatcccgc caactgtcag caaacagatg atcccgacat tcatgatcaa ggttgtagca
    22501 ggtgataata gggcagagat attggaaaca cgtaaataat tgttcgctag atcatttgtg
    22561 cttttatcga acttctctgt ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca
    22621 ccgctaagat tctgactaac gtgttcattg agctgatcta gtttttcttg cactttttgg
    22681 tagagaggaa cggttttttt gatgataaaa aataaaatga ttgagaaaat aggcaataat
    22741 gctaagaaaa acagacctac ttcccagtcg atcacaaaag ccatgaccac tgacccgata
    22801 cttaaaaacg gtgctctgat caataaacga atgaccattg ctaaagctag ctgaagctga
    22861 ttgatgtcgt ttgtcattcg ggtgatcaag gtatctgttc caaaatgatt caactcgttg
    22921 tgagagaaag tattgatttt tttgattagc tgattacgta actctgtacc aaatccttgt
    22981 gaagctactg aagcatagta ttggcaaatg atagcacaaa tcagaccaat cacagacata
    23041 gcgaccatcc ataagcccat ttcaatgatt tttcctcggt cattcatttt tagtccatta
    23101 tcgatcaagg aagccatcat taaaggcagg acaagttcga agacagcttc aagaaatttg
    23161 aagaacgggc ccaaaatgat ttgcttacga tagtcttttg cataacgtaa taactgaatc
    23221 atatgattcc tcctattatt tatttgtcca caattgaaaa aacaagtact accacattgt
    23281 agcttaggaa atttagaatg aaaagagaac aagccttttc ataaatgaaa gttttattat
    23341 g
//
LOCUS       DADVXB010000033        22883 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.033, whole genome shotgun sequence.
ACCESSION   DADVXB010000033 DADVXB010000000
VERSION     DADVXB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.033"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            611..943
                     /locus_tag="KB902_001006"
     CDS             611..943
                     /locus_tag="KB902_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBB6807848.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1562..1903
                     /locus_tag="KB902_001007"
     CDS             1562..1903
                     /locus_tag="KB902_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBB6807849.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            2017..2256
                     /locus_tag="KB902_001008"
     CDS             2017..2256
                     /locus_tag="KB902_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807850.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            2323..2562
                     /locus_tag="KB902_001009"
     CDS             2323..2562
                     /locus_tag="KB902_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807851.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            2648..3319
                     /locus_tag="KB902_001010"
     CDS             2648..3319
                     /locus_tag="KB902_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6807852.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3372..5348
                     /locus_tag="KB902_001011"
     CDS             3372..5348
                     /locus_tag="KB902_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6807853.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAVKNAEGKYYGGLVDTDKDGVKEAVWVDNVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGGLSAVVYFKKKA"
     gene            5361..6116
                     /locus_tag="KB902_001012"
     CDS             5361..6116
                     /locus_tag="KB902_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6807854.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            6113..6937
                     /locus_tag="KB902_001013"
     CDS             6113..6937
                     /locus_tag="KB902_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807855.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQPVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            7239..9338
                     /locus_tag="KB902_001014"
     CDS             7239..9338
                     /locus_tag="KB902_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6807856.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVLDGKNYDGALWYVEANGTWKKADTGGKLTVSSNTVTYTASDSFLANA
                     ANYGRDYILQLHMKAKNDAKGIAPNVATVTFNNDPNKGTQRTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(9376..11433)
                     /locus_tag="KB902_001015"
     CDS             complement(9376..11433)
                     /locus_tag="KB902_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBB6807857.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNHEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKASQAQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(11547..11759)
                     /locus_tag="KB902_001016"
     CDS             complement(11547..11759)
                     /locus_tag="KB902_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807858.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            11946..12413
                     /locus_tag="KB902_001017"
     CDS             11946..12413
                     /locus_tag="KB902_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807859.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            12410..12652
                     /locus_tag="KB902_001018"
     CDS             12410..12652
                     /locus_tag="KB902_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBB6807860.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            12670..12972
                     /locus_tag="KB902_001019"
     CDS             12670..12972
                     /locus_tag="KB902_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807861.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            13043..15097
                     /locus_tag="KB902_001020"
     CDS             13043..15097
                     /locus_tag="KB902_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807862.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     TNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            15097..17709
                     /locus_tag="KB902_001021"
     CDS             15097..17709
                     /locus_tag="KB902_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6807863.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PLTPATSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPDAKGTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSLVVNDPKNELYVASKDELEARGYDVYAYNLTEPLQSMSDNPLALIVKYWQRGDV
                     DTATQLANTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPTNEFKQLNALDEFMNQLPPGNLAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDQVCLKYDHQRKKYVAWYEFSQRELRDEEGNIV
                     YRKKRGETHLPEWEKEAVLTLDESKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHIV
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPAMDNMEGIMTVTAGRNMLW
                     DLFIQSYKQLRAKYGEDNADIIKENCQTHVYIMSTDDNTIEEFSKKVGNKTVEQENST
                     VNSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRRDLKGNKIRPYPIFNSE
                     KSNSPYAYQYLEDFDTLGRTIHDIDIYCTHADLDLKSLQIDYDYFLPDEDARDLYHGL
                     HEQLGEKIKENMFYKIVQSLENETAQKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     GKRLLLEAEKVVKE"
     gene            17706..20102
                     /locus_tag="KB902_001022"
     CDS             17706..20102
                     /locus_tag="KB902_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807864.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAAEMADSDKSGLSDLQKDRLRALQYRLELDDNGKEIPVKINDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGF
                     GNRKDVTPDNGEEQPDDKVPTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQY
                     RYKSNINSENEKRISDLPKRNQEVQTDDDSIDLPNDNGIEVGTEKSTKIGLPKTQNLP
                     MKDSRLNQFKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQN
                     VVTREAAPKPIQNVHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP
                     "
     gene            20152..20484
                     /locus_tag="KB902_001023"
     CDS             20152..20484
                     /locus_tag="KB902_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807865.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            20485..21078
                     /locus_tag="KB902_001024"
     CDS             20485..21078
                     /locus_tag="KB902_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807866.1"
                     /translation="MRVKGQNLVDKKSIFQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            21241..>22883
                     /locus_tag="KB902_001025"
     CDS             21241..>22883
                     /locus_tag="KB902_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBB6807867.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDEC"
BASE COUNT         8176 a         3531 c         4630 g         6546 t
ORIGIN      
        1 tttgcatact cctttttttt gagttataat aatacgcgaa gagagataat ttcattattt
       61 aaacaagcta aaaatcttga tattacttct tttcaggcaa tacgaatatt attcgcttac
      121 attttttgta taaatttaat tgtctgctat gcttgtgatg aattgatttt cgttttgcac
      181 ttttggatga taaatttgga caattgaaaa tacaaaaaaa agaaaggcgg tatgaactcg
      241 gaaggctggt aaccttcgtc agcgttcata cacggcatta agatttggcc cttaatgcgt
      301 taacctttca gtgttacggt attacccgca atggatttag tataacagat attcaaaagt
      361 gataccactt tttttggctg tgttaaggtt aaaaatacgt gatattacga tgaatctatg
      421 cctaagcata atgttataaa aatgtccgtg tggctctttg ccgtatgacg aacgctgaaa
      481 ttagagggaa cgcatgtttg gatgcgttcc ctcttttttg tttgtcatga acgaaaatca
      541 attctctatt tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa gaaattgggt
      601 ggtttatttt atgtcatata caggaatttt gagtctcaaa gatatttgtc actacggtaa
      661 acggtgtacc gctacagaga aaatcacgaa gaaactatca actggccaaa gtaaaaccgt
      721 tgtgcagtgt aagaaatata taatccagaa agacaaagtc tcagaggaaa tgatttatta
      781 cattgggaaa caaaagcaaa taattttaaa agatcctatc cccttaaaag agctatatcc
      841 aacaatcaaa catgtttatg accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt
      901 cttgcgttgt accgcaaaag ggatggggcg tttgatcggc tgaattgatc attctcataa
      961 cttgtatttt atcgtttttc gcttgcttga aaatattgtc gagacttcta aaggaactta
     1021 gagtcactag aaaaataagg agtagacttg atctatcaac aattcccttc ggggagtgac
     1081 ggggtaggtt ttaacgattg gtaacgtaaa aaattggtca atcgagtaaa tgcgcttgtt
     1141 tggatagtgg tgaaatgaat ttgtgtaaat aataagcgca gagtaaacaa gagggaattt
     1201 agaagttaga caagttagaa tagcgtctag attaatcatg agcagctact aagggatcta
     1261 gactttgacg caaactcatg gaataaggag taggtcttct cgtaatgggg aggacgcaca
     1321 agaaattgtg tcgtgtgctg cagtacatgt agatacttgc gaggacgttg attattggat
     1381 caatcgagca tttaccgctg tctactaggg tttctcgttt cggacgccat aaacgagtcg
     1441 aaatttttta tgtattttta agtaaacgaa aaacgataaa atatgaacaa gtcctgaata
     1501 aagtgaaaaa attgatataa aacatagaga aaatgaaatt tacgtaatgg aggaatgaca
     1561 aatgaaaaat tatgatccga atatacgatt gggcacacat actattaagg tttctttcca
     1621 acgttgggat tacaaaggat ttgtgacgtt tagaaggggc ggaaattgta aaggattaga
     1681 tgttttagca ttagacgagg atgatttata cgatcaaaca ttgactgata atccaattgg
     1741 attcggcttg ctacctgaag atgatgaagg taatgaatgg tttaaaatga cgcttatgaa
     1801 tgataatgga gacgaattat ctgttgaaga tacttggtca tatttgagtg attatattgt
     1861 cagcgttgaa atcattgaat ttgtagcgga taaagaagaa taaaaactgg aggaataaat
     1921 tttacagata aaggcttaga aggagtcacg acgattaata aaaaggtagt attaccttag
     1981 gcattgagta aggaatttat ttaggaggaa aattagatgg cgcgaccagt tttagaggcg
     2041 atggatatgg atactttgac aaaaggaagg tatgtacagc tgttagctcg tggttattca
     2101 cctaaagatg tattcaaatc cctgtctaaa ggaacagata tggaaaaaga aagattacga
     2161 aaagaattcg attattggag aacccataat ggaatcaagg atttgaaacc agcacggcca
     2221 gtaattaaac gaaagaaaaa gataacccaa gactgaagtg tagagcgtat gtgatcatag
     2281 gcttttttat ttttgcaaaa aacaaggaag gtaggaaaac tcatgaatta tgaagaaatc
     2341 gaaaacagaa aaaaagtgtc gaaagaaatg gaagaaaagt tgctaaaaac gatgaaacaa
     2401 aaacacctta aaagattatc tgtcatgcaa tatatcaatg atatgcagat aacaggaaaa
     2461 gagaaagctt gtttgttagg ttcaatgaaa aactttgaac agttgagacg aacttatgtg
     2521 aaaaaaagtt ctaattgtca actattgtta gaagtctcat gacattcatt aatagaattc
     2581 atttttaaaa ctttttctat ggaaatgaga aaaagatttt ttgttttgtc tgaaaggagg
     2641 tagctggatg agaaaatggt tatttggttt tttaggagtc gctttaatcg tcttttgcag
     2701 tgtgtttggc tatgttagct accaaaaaca tgaaggagag gtgtttaagc aaaatataga
     2761 aaaaaagatg cccgtagatc aaatcaatgc acatgcaaag agttataagg aggatgcaac
     2821 gaacgtcaat aatgatatgt ctttggggca aatgttgtcc atacaaaaag aagcaatcga
     2881 aatgggcgtc aataaacaag tatttgcaca aattcagatt cctgcacttg gtttagcatt
     2941 gccaattttt aaaggggcaa atcaatacac tttgagtctt ggagcggcta cttattttta
     3001 tgaagatgct gaaatgggca aaggaaacta tgtcctagca ggtcataaca tggaaatgcc
     3061 aggtgtttta ttttctgata tccaaaagtt gtcattaggg gaggtgatgg acttagttag
     3121 taacgatggc gtctatcgtt acaaggtaac gcgtaaattt atcgtacctg ggtactttaa
     3181 attaatcgat ggcgttcctg aagagaactc tttcttgtct ttgccaaaga aaggagagaa
     3241 acccttatta acgttgttta cttgtgttta tacgtcacaa ggaaaagaaa gatacgtggt
     3301 acagggagag ctacaataac aaggttttaa tcaacgcgag tcgttgaaat atgaaatgag
     3361 gagagtaaaa aatggcaata aatcggtatg taaaaaaagc tggaatgctt gttggaatgt
     3421 taggaatcat tgcaggctgc tttcaggggt atcaagtaca tgcagaagat gtcacgcaaa
     3481 aaacaccacc agagaaggtc aatatcacgg ttcataaatt aatgtacgat caaggaacgc
     3541 aattgaatgt tgatattgac gggatcaaaa acgatggtta tacgcacgat caatatccta
     3601 caggtgtaac gaaatacaac aaggcagatt atggtgatgt tgagtttacg ttaggaaata
     3661 ttacggatca agtattaccg agagaagatt ctgatctaac caacgcgaaa gtggacgaga
     3721 ttgtacaaga tgtagaagac aagggatcta acagtgagta cgtcaagaat gcaaccaaca
     3781 aaattacttc agctgtagat gaaaatggtg agatcacttt tactgatcaa ccagcctatg
     3841 tcaattccaa agggaatgta tatgtggttt atgaaagtaa atccgctgct ggattagtca
     3901 cacaaaaagc aaaaccaatg gttgtgattg cgccaatgac agataaaaca ggatcaggat
     3961 ttttaaaaaa tattcatttg tatcctaaga acattgtttc taagttgagt tttgaattaa
     4021 cgaaatttgg tgacgatggc gcagaccaaa gcaaacaaac ccttttaaaa ggggcaaaat
     4081 ttgagttata caagggcgaa cctggaaaag gaacaaaatt gggtgatctt gtatcggatg
     4141 atcaaggaaa gctgactgcg actgatttga cgttaggaaa atactatttt gtggaagttc
     4201 cttcggaagt tgtagtggga tcagatcaag aaccaacagc agatcaatat ttattaggcg
     4261 cagacgctcg caacgatgcg cacaataaat taacctttga aattacgaat gatggcgtga
     4321 caagtgactt aaaagcttca tacgtaaact ataaagcacc agtgatcgat aaaacagtaa
     4381 caaatggaac aggacaagaa cattctttcc aaattggtga cgcagtaaat tatcaaggaa
     4441 cgattcatat tccaacagac attgcaggtg gaacagatgg gatcacagta aacggtgtga
     4501 aaagcgaaac ttctccttac agtgtattta aatggggaga tacagcagga caaggacttt
     4561 cttatgtcgc tgctaaagca aatatcaaag taacaaataa agatggatct gtggtattaa
     4621 aagaaaatac agattataaa atccaaaatt cagaaaatgg ctttgtgatc gattttatcg
     4681 tgaataatgg ccaagtaagt gatactgtag caagtttaca cggacaagat cttcaaatga
     4741 cttataacat gtatgtaaat gacagcgcag ctgttgccaa tccattaaca aatagcgtgg
     4801 atttcgttta taacaacaat ccattcaatc aggaagaaca ccacgaaaaa acgaaagctg
     4861 acgttgtgac ttatggtgca aaattcttaa aagtcgatag cggactattt ggaacaggaa
     4921 tcaaagcaac accgcttgaa ggcgcagaat ttgctgttaa aaacgcagaa ggaaaatatt
     4981 atggtggatt agttgatacg gataaagacg gtgtcaaaga agcagtatgg gtagacaatg
     5041 tagcaaatgc agcgattcta aaatcagata aagaagggca ctttgaaatc actggtttaa
     5101 ctgaaggtga atattcattg gaagaaacaa aagcgcctga aaactatcaa aaattaacag
     5161 aagatattgc atttaaagta aacaaaaact catttaaaga ggaaaatcga atcactgtta
     5221 aaaataatca aaaagcagct attccattaa caggtagtaa tggtttccaa acgtatgtat
     5281 tgatctcttg cttgttgcta ggagcagggg gactttctgc agttgtttac tttaagaaga
     5341 aagcctagaa ggatcagcta atgattattc gtaagccccc aaaaagaaga gtcatgcaca
     5401 aactgatgat atttttttgg ttgctgtcgg cagtagcagt ctatttaatt ccagttgtgg
     5461 aaacaaatgt agcgaaattt caacaacagc aaagaatttt agccattgaa aatcttgaaa
     5521 aaacagattc ttctttggat gttgcgaaaa tagagttagg cgatcctgtt ggtgttctta
     5581 caattccaag tatttcttta aaactaccaa tttatgacgg aacttccgac aaaattttag
     5641 agaatggtgt agggattacg gaaggaactg gcgatattac aggaggaaac ggtaaaaatc
     5701 ctttaatcgc ggggcacagt ggactttata aagataatct tttcgatgat ttgccttcag
     5761 taaaaaaagg gcaaaaattc tttattaagg taaatgaaga acaacatgcc tatcaaattt
     5821 atcgaattga agaagttaaa gcagaagaat tacaaaaaaa ttatttagat tatcttatgc
     5881 ctgaaaaaga ccaagatagg atcacgttaa tgacatgcac accaaaaggt gtcaactcac
     5941 accgcttttt agtgtatggt gaacgagttt ccttcagtaa agaagattta aaactacaga
     6001 aaaaagcaaa aaataggaaa tcaatttcat tggattggcg attagcactg ctattcgctt
     6061 ttttttgcgt tcctattatt tttatttata aaaaaataag gaggagatcg gaatgaataa
     6121 gagaaaatgg ctgtttgttt gtgtagcagc tctcttttct actgtagctt attcgcaact
     6181 gtctttcgct gacagcagtg atagtagtac cactcaaaca atagataatt caattactgc
     6241 accaagcgaa acggacagtt cggagaatac tacagaagaa acggcagatt caaatataag
     6301 ctttactgaa tcaacgaatc caacgtcaga aagttcttca gagacttcag aaaagccgca
     6361 agacgtagaa gatacgcaag tgatcaagca agccattcat attcaaaaaa ttatttcttc
     6421 gaatcaaatc aacaatcaag gcagtcaagt agcccagcaa gaaggtatca atggcgcaaa
     6481 gtttattgtc tacgatatca cgaatatctt agaagaaatg tcacaagatg ataatgagaa
     6541 aaatcaacct gtagaaataa ttgagtcaaa attgaaagat cgagcaaaaa aactttcata
     6601 cgaccagttg aaaaaagtgg ctgaaggaga aaccaaaacg attgatgatc aggaaggcgt
     6661 gattgaattt tccattgaag tacctgcaaa caaaaaacaa gcatactata tcgttaatga
     6721 atcaagccct gaaaacattt caaacagtga agatattgtt ttattgacac ctgtttcaaa
     6781 tgaaaaaggt gaatttttga cggatgtttg gttataccct aaatcagaga aatcagagcc
     6841 gaaagaagaa attaaaaaag ttgtgtcaac tggtgtaaag aagaactttt ttgaaaattg
     6901 ttgggaattt tttgctcaat tattttttga taattaggat gaaatgatga aaataataag
     6961 aatattagtt tttaatctat cctttttagc cgcaacatta ttgtgttgcg gtttaatttt
     7021 ttctcaatta tcaatttatc caagatatca acgattgttc attcattttc taaacattca
     7081 atgtgcttcc atgccattag aggtgattaa aaagctcttg atcagtccaa tttttatggt
     7141 tagtttggtt cttcttacag gattggtaac gtgggtatta ggaaaaaaag aatgaaaagc
     7201 ttacgatcgt ttaaaaaaaa tattagatgg agggcattat ggaaaataaa attcattgca
     7261 ctacgggaag agtaattact ttagtgttgt ttttgttcct tcttcttttt gcgaggggaa
     7321 ctgcagtcca ggccttagaa aaagttgatc cgagtcaaat caaagaaaat aataatctgg
     7381 tgctttatca tgatagtgat tcattgagaa atatcgaagt aactgggatc aatggattta
     7441 agatactaga tgagtattca actaaaaaac aaaaagtact tgcttggcca aaagtcaaag
     7501 atttgaaaag tacgtcaaaa atcgttgccc attatcaaaa agtaggtact tatctaggaa
     7561 aagaaattga ttgtgacgtg actttttcta attttgtagc gcacgctggg gttaaccaag
     7621 acggattagc taaaacaatt aatggcaaaa agtattataa ttatttgctc tttgataaaa
     7681 atatttatcg aggatttttc atgcagtcaa tcaatgtcat gaatgcaaaa ctagaattta
     7741 agtatgcagg aacaaaaaca aaagtagctt tgagtgaacc acagccagaa attcaatcaa
     7801 aaatgagatc gatgagagca gctggtattg atttaaacga tacatttcta tccatttata
     7861 gtttaaatgg acagtatcag caacgtgtgt cttggtataa tgacaataat gaatctgtcg
     7921 gtgaacgtaa tattgatatg agagaatttg ttgggtatga aaaaatgggt agcttacctt
     7981 attttgtcac aacagataca gcatgtgcag aatacaaagc tcctgcgtta tcaacaaaca
     8041 atttaacttc aaaagtagtg ggaggacgtg cagaaaaggc ttatagctcg aatgatcatt
     8101 tcaccgatgt tgtaggagct gatacttatc acagaagtgg tgtaacgtat acgcttcaag
     8161 gcgcttcccc aacattcatg attggcgcaa atacgaatag tatgatgttt agctttgata
     8221 ctgcattgct atggacacca caaccatcga agcctacaaa agaagtgttt aacaaagcta
     8281 atactgaaga ggcagcacac aatattgaca aaaaagtgat tccacaagga tcagatgttt
     8341 actatcatat tcaccaaaaa tttgatgcat taacagtcaa cacaatgaac aaatacaaat
     8401 catttaaaat cactgatacc tttgacagca aaaattttga tatggtattg gatgggaaaa
     8461 actatgatgg cgcattgtgg tatgttgaag cgaatggtac ttggaaaaaa gctgatacag
     8521 gaggaaaatt aactgtatca agcaatacag tcacttatac tgcttctgac agctttctag
     8581 ctaacgctgc aaattacggt agagattata ttttgcagct ccatatgaaa gcaaaaaatg
     8641 atgcaaaagg aatcgcaccc aatgtggcta ctgtaacgtt taacaatgat ccgaataaag
     8701 ggacacaaag aacaaataca gtagaaaatt atttctctct taaaccaaat aaaaaagtgg
     8761 aacaagatgg gaaagatgtt gatggtcgaa atgatggtaa aaaaggaacg cctacagctc
     8821 ctttaaatgc aggatctgaa gtacaatatc tagtcacaca aaaatggcat acaaaaggtg
     8881 tagacattgc gctcgatcat tacaagcaat ttagtattca agatccagtg gaagctcgtt
     8941 tgacgtataa agaaggttct gcgcgagtga tagatatgag tacaggaaaa gatattactt
     9001 cagaaggtac actaacctat gatagcaatt caagaacgct gaagtgggaa gcttccgctg
     9061 atttcttaag taaaaatctt ttagatggac gagaaattca actgatattt acagctaaaa
     9121 ctcctttgaa tgaagaattg gatatcgaca accaagcaaa agtttcagta gaaagtattg
     9181 agaaagcaac taatgtagta acgattgggg taaaacctaa cttacctcag atcattgtgc
     9241 caaaaactgg atcgaatcat ttagtgctaa ctgttattgg aagtatatta tttcttactt
     9301 tagcatcatt gggctatgta gttttaaaac tcaaataaat ataaaaacaa ggctgagaat
     9361 cagccttgtt ttcttttatt tgaagattgg attcgcacta ataaatacat tatctacgcc
     9421 aattctacca gcagagtcaa ctacaaaatt atgacctaat ccgagaatac tttggttatt
     9481 ataaagtaaa tttgcattat gggcagggct atttttccat cctaccatgg catcgatagc
     9541 accatcgtct gataaaaggt catcaatata cagcccagtt tgacttatgt tttctccctt
     9601 agcaccgtag cagcctaagc tttccaataa atcttggaaa gtaccaccac cagggcgata
     9661 gtgactgaag ctgacttgta attctttagc tcgaatatct gcagcctgtt gaacaatatc
     9721 attgaattgc attggggcaa caccattttg ttggcgataa tcatttaacc aagcaagttc
     9781 tttttgacgc ataaagttac gtaattcgtc taatgaaatc tttttatatt tgaatgtgat
     9841 tgttttattt tgatcgacgt tattaatgga tcgttggccg tttttatcca cggtaacggt
     9901 aggatcgtca tttctgcaca agaaataatt ttgatcagtc atgtttttcc aaggagtagc
     9961 aaagctatcc ccttcgtata ctgtttttga ttcactagag agaacagcgt tggtatcagc
    10021 atttacatga ttaacagtca cattaaattt acgagtgtag ttgaaaatat aattttgact
    10081 ttcagtcaca ttgtttaagg ttactgaatt tgttggttct acccgatcgt ctaaaacata
    10141 tccttgaata gaaggagcag ttaaagtgac actgtcaccg tgagtgacat tgactatctg
    10201 ttctttcaaa atattaactc gtccttcgtt tttgtagttg ttattgcaca acaaattgat
    10261 ttgatgcact tgattataat tgaatgtgat tgttgtatta cctgtgattg ttttgctttg
    10321 agtatcatta ccaatcactt tgtagctaaa attatcttta gcgccttcgc tatatttaaa
    10381 tgcttttgcc ttagcagtgt aagtagaacc agaagttact tttgcttgat ctgtagcaat
    10441 cacttgacct gtttgattgt caatatggtt aatagtaacc gtatattctt ttggtgtttc
    10501 aggtttgtgt tgcaaccctt taaatgcagc atcaagacta tttttagcat tatttacttg
    10561 ggcttgagaa gccttagaat cgtctagtac ttttttagca ttggataaag cagtctgaaa
    10621 attattccaa gattcttctg taaaatctcc tttagcagtt gattttactc ggttgtataa
    10681 agcttgtaat tcagctttat tcacagtagg aactggtttt ttctttaatc ctttgtaagc
    10741 agaatctaat ttatttttgg cactatccac ttgtttttga gtcgcttttg agtcatttaa
    10801 cactttctta gcattgttta aagcggtttg gaatgcgttc caggtattgt cggtatagtc
    10861 acctttttta gttcccttaa cgctcgtata aagagcttct aaagctgatt tattcacttt
    10921 gggtttagag gtgtcagcgc cataccaacc gataccttcg tatttccagc catagtcttt
    10981 ggttaaccat tgtacttctt tccaacttgc agtgtagtga tgtgagccag attttacacc
    11041 aggaaggaaa aggcggtaga tcggtttatt atttttttcg gcagaacgcc aggctggccc
    11101 ttcataagtc cagccgtaat ttttagtcaa ccatttcact tcatcccaac tagctgtgta
    11161 atggtgatca cgaagacctt tattgtacaa acgatagaca agatggccac cgctagtcgg
    11221 tgcttcccag gcggggcctt cataatttcc ccattttatc tttactagat ggtcacgttc
    11281 ttttttgcta gaggtgtaaa aatgttcatg attatttgga ttgtaaaggc gatacatgac
    11341 gttagttgaa gcagcgtcaa cagatccagc aagactaagt gaggcagcaa atgttccaat
    11401 agctaaaaca gtttttggat taaataattt cattttttca actcctaaat ttaattaaaa
    11461 atgtttacat gattattata tatcggctaa ccgatatagt caataaaaaa taagaaaagc
    11521 cttatataat tttggctttt cttattttat ttgttagttg aagtattaat atcaacgatt
    11581 tcttcagcca atttatttaa tttcatagca tttatgaatc tcatgttgtc tatactagag
    11641 cgtttgttgg caaggtcact tactgtagtt aagggtacgc cagattctat ggatatagaa
    11701 cgaactgatt taccactatc aaacagcaac cattcgattt tctttttatc agcgtacatt
    11761 tcaatgctcc ttcttgtttt ttctttatta tagctctttt ttgtaataaa tcacaatatc
    11821 aagagaaaaa ttttctatag aaaggtggat ttttatgagt attcgttctc cgtgtatcca
    11881 aatgaggttt gttgctactt tcgttatttg atatactaaa aataaacaac gaaagaagga
    11941 ataaaatgaa gaaaaagcaa ctatggtttg tctctatgtt tgcaatattt tttattattt
    12001 taagtggatg ttcaagtaat aagaaatcgg aagctaaaga agataatagt ttattgcaac
    12061 caggaactgt ttggaaagaa gaagtaggtg gtcttattca taatttaaaa attatagatg
    12121 atactacctg ggaatattct gaaagtgtat ggcatccaga tcctgtacaa ataacagtta
    12181 agaggcaaaa agactatgaa ggtttagaaa gatacaaaat agtagattct gcaggtatta
    12241 gggaatttat aaacaaacct gattcattat ttattgttgt tccctatgag aaggatggcg
    12301 taaaaaaaat aatttttctt ggatctagca aggatgagaa gcgaacgaaa gagaaattaa
    12361 ttcatgatgg atcagagtta aataaataca aattacaaaa gactagtgag tgattgctag
    12421 tctttttatt tatcctgaag gaggaatcac agtggcaaaa gttaaaacac cattcgaaaa
    12481 agccgcgtct aaaatcttag aacgccgtgg tgtttctgaa atacagtgga aaaaagaagt
    12541 tcttgaaaaa gcacaatttg acctattacg aggaaaagat aaggacttag aagaatatat
    12601 ctatcaacgt gaacgtgaaa aacttgtatt cgatgaaatt attaaacatt aaaaggagcg
    12661 aataatctta tgtttgaatc aattacaatg aattttttaa ctcaaccgaa agtagtagct
    12721 gcagttgata tttttagagc attacaaact gccgcaacta gtttgaaaaa taatctgatg
    12781 atttttgctg ctgttgcggc agtggcttcc attgctcttg gaggtatttt cttcttcttt
    12841 gggcgaagag gagctgaaaa cgggaagaca cacgtaggtt atgtattgtt gggggtagga
    12901 gttattttag ctgccgcttc tattgtagtt tcaatgttct caatgtttgg acaaacccca
    12961 caaggactat aaaaaaacaa gtagaaggag taaaaagtac gtggctactt tttactcctt
    13021 tttttatgga aggagaatat tcatgttttt tacgatttca ggcaatgcaa aattggataa
    13081 agagttaata agaaaagcaa cgaagaaagt gggaaagcgt acttcctttt taccgaaaac
    13141 aattaaatat tctgtcattg aaacggaaga acagctacat gtgttaggac aagtgttaga
    13201 acaagagaat caatcttctg ttaaattgac tctcacgtta catgataaag aaggaaaaat
    13261 agaaaaggct ggcacagaat acgtttttgg ctcactggat tatcaaattt cagaaggttt
    13321 ttatcctaca ttgattgatt taatccgcct agatatattt aaagatacgg atgaaaccat
    13381 gagtgtggaa gagtcttatc gaaacgaaaa aattttacaa gttttagaag aagagttaga
    13441 aagcgaccaa agaaaagtga atcaagtgag tgaagtcgaa gcaaacgaag aagtaccatg
    13501 ggaacgccca atctttccaa aggatgaatc aaaagaaaaa gagaaaggaa ttattgacga
    13561 acaagctgac attttgactc ataaatcaat atttgaggaa gagaacgagg taatgggtca
    13621 attggaggta gatccctttg aagaaacaat ggaggatgaa gagacggccg aagtagaagt
    13681 tgatccagtt gaagctaatg aagacccaac atggactgaa ggggattctc aggaatatat
    13741 tgaaccactt atcagtgaag aagtagagaa aaatgaaaca gagatacaaa aggcaacggt
    13801 atttgattat attttggatc aatatccgcc agagcatgaa tggatgaaag aaaaaaataa
    13861 attattttta aatgaacttt attcgaaata tcaattacct caaacctatc aagcattttt
    13921 agagagtaaa gaagaattaa tctcacaggg taaaggcaca cttttagaac agttagagtc
    13981 tgtccaatca acaaattggc atgagcttgc acaagaagat ttattagcta cttttgaaga
    14041 acgtcaacaa gaaacagatc aagaaattaa tgagtatgcg acggaacagt cgtcgaattg
    14101 ggagaaagca aaagaggaac taaataaaga agaacagcga gtgattgaag aagaagtaca
    14161 aaaaattaaa gagcggtacg aaaagaaacg tgacaatgcg tattccttgt gtgtagaaaa
    14221 gatcaacaat tttactcaga cgaatcaaga agcattatcg aaagaaaaag aaaacttatt
    14281 aaaagaacgt ataaaagaac gaaaagaaga attttaccga gggttgcgta ctgataagct
    14341 aaggattagc aaagaattaa atgaacaact gaataaactc tatcaaacta cgactgaagt
    14401 tctgatggaa aaacacgagc agatccaaca agaattacaa gcacaaattc caaaatggaa
    14461 aaaagagtat gaaattcacc aacaagaatt gaaagaacaa gaagaaaaac aacggaaaaa
    14521 agaaaaagag cgcgaacaat tagaactaaa aaaacgtgaa caggatcttg cggaacaaaa
    14581 aatggcgata gaaaaacaac ggctagagca agaaaaggaa aaagaagcag ctgctcgtaa
    14641 ggaacgtcaa gaacaaatgg atacattgcg acaagcacag ttaaattatc tgacacatcc
    14701 tcaaccagta gctgctgttc aaacgccagt gaacaaccaa acaaatctaa ctccttcacc
    14761 ccagcgttcc tttaacggat ggatggtggg atgtattgca agtttaagct tgcttctagg
    14821 tggaggaaca gtatttgctt ttaatcatat caatcaatct tcacaggctg attctgtagc
    14881 cacaacggcg tcaatcaagg aagaagccca ggaacaagca agaaaagagt atgaacaaca
    14941 attagaagaa ttattgaatc gtaccaatca gtcaacaaca gagtcaagca tggaaaatag
    15001 caaagagagt gattctagta aggctaaaga aggatcaagc gattcaactg tacaatcaaa
    15061 cacttccgaa agttcagaat caaatgaggt gaaataatgc gtgttagaga aacaacgaag
    15121 cgaaaagaca aacgattcaa tttagaaaag aataggtatc tttctcattt ctatcgctat
    15181 actccctcag gagaagagct accagaaaaa catgacaaac gcatttcgaa aaagattttt
    15241 tatagtggac ttgtatacct ccctttagag tatttagtaa caagagtacc agaagttttc
    15301 aaccgattgg aaattgttaa gggaagctta caaggaataa atctgtttca attacaggaa
    15361 atgccacagg tctttcattt tgattcagct ggtttttgga atcctttgac cccagcaacg
    15421 agtttaggta cacgcttagt tgtttctacg atttgtgttg ttccagctgt acttatgggc
    15481 ttgaaaatgg acatgtggtt tcgtccgtta gcggatggac aaaaagggga taatcggtta
    15541 atgacactaa aagagattca acaaatctat cctcaaatac cagacgcgaa aggtactttc
    15601 cctggatatg gtggcattcc tatcactcac tataaaaaat attggtatat ccaaacagat
    15661 accgttaata cttgtattgt tggtacttct cgatcaggga aaggacagat tgaagtatta
    15721 gcaactattg ataatttgtc tcgtgcagaa aaacaaagtt cattggtcgt caatgatcct
    15781 aaaaatgagt tgtatgtagc cagcaaagac gaattagaag ccagaggcta tgatgtttat
    15841 gcttataatc taactgaacc gttacagtca atgagtgata atcctttggc tttaattgtg
    15901 aaatattggc aacgaggaga cgtggatacc gctacgcaac tagcaaatac atttacaaat
    15961 acgatttatt atgatgccaa tgcttcagac aacaaatact ttaacgaaaa tgcgcagaaa
    16021 gctgtcaatg cgcttatttt tgcgttgtta gaacaagccg atcaaacagg ggattactcc
    16081 aaattaacac ccaataatct cgtcgaactt ctttctgaga ttggcggttt taattatcaa
    16141 gatcctacta atgaatttaa gcaactcaat gctttagatg aatttatgaa tcagttacca
    16201 cctggaaatc tagcgaaaaa acaatatggg gcaacaaaaa ttggttctga taaagcaaaa
    16261 ggcaatattc tatcaacagc gatcacagga ttgaatccat ttaccctaac aaaaattgcg
    16321 aaaatgactt ctcaatcaac cattgattat aaatcggttg gttttccaaa atatttggat
    16381 ttgaaattac atgaaagtct tttaaatcaa cgaatcgtag tggaatttta tcatcaagga
    16441 aagaaatttc atgaagaacg agtaaaagtt ggttatagag gtttttgtga aatcaacttt
    16501 gattgtcatt tagagcaagg ggatcaagtt tgtttaaagt atgatcacca aagaaaaaaa
    16561 tatgttgctt ggtatgaatt ttctcaaaga gaattgaggg acgaagaggg taatatcgtt
    16621 tatcgaaaaa aaaggggaga aactcatttg ccagaatggg aaaaagaagc ggttctcaca
    16681 ctagatgaaa gtaaaagtaa cttactagta gagtctattc ggatgcacta taccgacaag
    16741 ccaatggcta tttttatgct tacacctgat tatgatccat ctaaccacat cgtagttagt
    16801 atctttctga gccagttata taaagagtta tccacgcaat gtgttaagac caaaggtgat
    16861 aaatgtcacc gaagaattca tttcatttta gatgaatttg ggaatatgcc agcgatggat
    16921 aacatggaag gaattatgac agttacggca ggtcgtaata tgttatggga tctatttatt
    16981 caatcatata aacaactacg tgcgaagtat ggggaagata atgcagatat tatcaaagaa
    17041 aactgtcaaa cacatgtata tattatgtct acagacgata acaccattga agaattctct
    17101 aaaaaagtag gaaataaaac ggttgaacaa gaaaatagta ctgtaaattc tttaggtatg
    17161 aatacacata tcaatcgtaa tgttgattca gatcgtatct taactcctga aagaatttct
    17221 acttttttag aaggagaaac gattgtactt gcgccattga aacggcgaga tctaaaaggg
    17281 aataagataa ggccgtatcc aatttttaat tctgaaaaat ccaatagtcc ttatgcttat
    17341 caatatcttg aagatttcga taccttaggt cgaaccattc atgatattga tatttattgt
    17401 actcacgcag atctcgattt gaagtcctta cagattgatt atgattattt cttaccagat
    17461 gaagatgcta gagatctcta tcatggactg catgaacaat tgggagaaaa aatcaaagaa
    17521 aacatgtttt ataaaattgt tcaatctctt gaaaatgaga cagcccaaaa attattaatt
    17581 caattttacg aagaacaagc aacggatcgt cttcaagaat atgttgaaaa gttgatcaaa
    17641 aatgaagaaa tttctgaaat gattgggaaa cgattgttat tggaagctga aaaggtggtg
    17701 aaagaatgat cattggagga attttttctg gcatagccga ctggtggtca ggtttatttg
    17761 gagaagggga tgcagacccc aaaaccgtaa caaaagtctt acaagattat gggaattatc
    17821 tgcagtatca agatgtattc agttggattt gtaatacttt tttatgggga ttgatcaaag
    17881 ggttatataa tctcaatact ttactagaaa aaaccattta tcaaagcttt gatttaaaag
    17941 acttattgaa cgccgctggt gttaatgaac tgtttcaaag tttgattagt aaggtattgg
    18001 ctcttttttg tgtcgtcaca ttaatttatt taggcttgaa attttttatg agtaaacatc
    18061 caccaaaaat caaaaatatc ttggttaatc tattcatggc tatgattttg atttttggtg
    18121 gtagttctct gatcgatgaa gggctaaaca tcagtaaaaa cttttacgga gacgtcactg
    18181 cagcaaataa agcagataaa actggttcac ctgcttttca aattattcaa aataatgtga
    18241 tcgatgtaag tacattacta gcaactgacc cgaataaagt agaatccctg ccaacagaca
    18301 aaagaaatgc attaacagcg aaaaatttta aaacagcgaa tatcaatggg attattactc
    18361 ctgatcaagc cgctgaaatg gcggatagtg ataaaagtgg attgtcagat ttacaaaagg
    18421 atcggttaag agcgttacaa taccgactgg aactggatga taatggaaaa gaaatccctg
    18481 ttaaaattaa tgatgaaggc ttagcaaaat atgtgtatac ttcagggtat cgtcgataca
    18541 ttagtagtcc agggattatt ttagctggtg aatcttcttt ggcggtggcc tatttattta
    18601 tcttgtttac gattgttact tgcattattg agctggtatt taaaaaattc tatttagtga
    18661 ttgccgcgtc aacggacttt gagacaggac aacggatgaa aagtgcgata gaagatattt
    18721 ctcaatcctt cttgttattg gcatttacaa ttttagaatt acgaatctat accttaatgc
    18781 tttcaggtat cggtgatttg catgcggcag gcaagatcaa cggatttttg tatgttgtcg
    18841 ctttaattgt actaaccatt gcgctattca aaggctctca atctgttacg aaaattttcg
    18901 gcgttgatac gagtctgaaa aacggcagca attctcttct tagcatgttt gccttaggaa
    18961 atattgcgaa aaatgtgggt agtggggcta aaaaccttgc aagtgctggt aagagtggtt
    19021 taagcaattt aaatgatatt cgtaaaaatg gatttggcaa tcgaaaagat gttactcctg
    19081 ataacgggga agaacaacca gacgataaag tgccaactgt gccaaatagt aagaaaacag
    19141 tttcggaaat gtttgggaaa gcgaagaatg gtgtttctaa agccgcagaa ggtcttggtt
    19201 acgtcaatga acgtgggtta aaaggaacag ctgaagatct tacagaaaaa gccaaagaca
    19261 ccttagaaga gaaattagac ggcacgagag ctaaagaatt ggctgaagct gtgaagaatc
    19321 catccgaagc actagaaaaa caaaaagaaa aagcttcaga agtcaaagaa ggactaaaag
    19381 atgcgtatgg cgaaggacaa gtcaatgcag cagtgaaggc aaatacaaca agtgaaaaag
    19441 aaaatcaaga aggtgcagcg attccttcag ccaaagatca ccaagatgag ttacattcta
    19501 acgaaaattc gatcggagaa aaagattcag aagaaggaca acatggtcag ttaccaaaaa
    19561 ccgatccaga acaatatcgt tataaatcta acattaattc tgaaaacgaa aaacgcattt
    19621 cagatttacc aaaacgaaat caagaagtac aaacggatga tgattccatc gatctgccaa
    19681 atgataatgg catcgaagtt ggaactgaaa aatcaacgaa aattggtttg cctaagacac
    19741 aaaatttacc aatgaaagat agtcgtttga atcaattcaa agagaatgat caaagctttg
    19801 ttcaccaatc aactgcaggt aatgttcaaa tgaaaccaag tcgtttgcct gaaaatggaa
    19861 atctgacaac tgtttcttac aatttatctg aaagtggtga gacagggaat gcgtccgttc
    19921 aaaatgttgt gacaagagaa gctgcaccaa aacctattca aaacgttcat acaggttaca
    19981 agccagcaaa tgtggcattt actgcaccaa caaaaataaa tgtgacaaga gaaactaaaa
    20041 acaggaacaa tgcattgaaa gaacaactat tgagggatat caaacaggat atcaaaccat
    20101 aaaaggccta caagttaggc cttttattta tatgaaaagg agaaatcaat tatggataaa
    20161 tatataaaca tgaaaaaccc tccaagattt agtggagaat ggaagttttt cgcttttttc
    20221 tttttagatc tattaacgct tggtggctgc tttttttggg cgaaaatggt caataatctt
    20281 gtccacttac cactcttttt tgcactcttg aattatggat tatggcttgc gatagcgtta
    20341 gtgattgttt ggcgacccta taataaccct ggtcaacgac aaatttttgc gattatcgag
    20401 tctatttttt ttacggacaa gaaccattat catgcgttag atcctaaccg aaattatcat
    20461 ggtacgtata aggaggatga ataaatgcga gtcaaaggac aaaatttagt tgataagaaa
    20521 tccatttttc agtttggaaa accagaagaa cgatctatct tggatttatt tccttataaa
    20581 tcctgtacag aagagggagt cttagttact aaagaagatc attttcaacg ttattatcgt
    20641 gtagtttcta cagacgtgga aggattaaat gaacaagaga aactagaacg aatgaatcag
    20701 ttgaccaccg tcatgcgtac gtatgtgcca acaattaagt tagttagttt gaccacagag
    20761 acggatttaa cggaacaaat cgtgcaaaag cggcaattat tagataaaaa tcgtatggaa
    20821 cagtccttag gaagaaatct acaacgatta aaaaaatatg aaaagaaatt agtcgaagaa
    20881 atccaggaat tgaaacgagc agaacaagaa cgtcctgact taagcttctt tttcgtcatt
    20941 gaaggaaaga caatcaagga tttacaaacc agaaaccgtc agttaatgcg atctagtggc
    21001 attttagggt taaaaccact ctacaaaaaa gaattgatca agattctgta tcgaatgaac
    21061 aatatgaatg atgagtagga atggagaaga gagaatgaaa tatccgttga tatggttaga
    21121 aaaagatgtt ccgaaggaag agatcactag aaaatttcct cacactttaa gcttggggaa
    21181 gttgggaaaa gggcaatctt ttaaccaagt agagaatcaa aaaagaagag gtgattgtac
    21241 atgttagaag cgattaaaac agctttttca ccacaaaatg atcaaaaagt acttgatcca
    21301 ttaaagcaac taggaaatcg ggaaatcgaa attttaaaat ccaaagggta tgatttagat
    21361 tttttaaaac aagtgatgcc acaaggtgga ttaaattttg atgaagagta tgtgacctat
    21421 ggaaatggtt attcacgatg tgtgacggtt tatcattaca caaaaaatcc tactcttttt
    21481 tggttggcca atctcatgaa caatcctcat acagtggcca cactcgatgt tagcacagat
    21541 gaaaaacaaa aagtgattga tcaaatcaac cgcgcattag atgaattaaa tgatcgatca
    21601 gataatgaac gaaaagcgac tgaccgaaat aaaagcgcgg aagaatacct ggaactagcg
    21661 gaatatgcta gaaaattgac ttctaatggg gaaatttcta aacaagtcaa agtgagagta
    21721 catgtttacg gaaatacgat ccaagaagtg gatgaacggg cgcaggaact gatcgaaaat
    21781 ctaaaaggga tggattatcg tgcggtgact tatctgcata aaaccaaacg agattggcaa
    21841 tcgatgttta ccatgttcga tgaacaagct gaatggttcg gaaatatcaa agggcaatca
    21901 cttccatcgt taaacattgg cggaggattc ccgttccacc accaaacgct aaaagatcca
    21961 ggaggcacac aatatgggga aaccatgaca ggcggcccat ttgtctggaa tgccacgtat
    22021 aaaaatagtg tacgtttatc taccaatacc ttgcttctag gaatgatggg agctggtaaa
    22081 tcgaccgttc ttaaaatgat cgcggaagcc catttagctg caggagactt tatttggggc
    22141 tttgaaaagg gaaaagactt tattcctttc ttaaaggaat ataacggtat tatggtgcgt
    22201 ttagacggat ctgacgggat gatcaatcct ttagagatct ttgccacacg gacgtatgat
    22261 gaagcatcca gtttatatga cgatggttca gtcaaagatt tgaagatcaa tgaagcagcg
    22321 tcctatcaaa cgcacttaga caaagtagtc tatcaggtac agttagtgag tcctcagcta
    22381 aaaggaacga tgaaagcaga attcaagacc tacttgaatc gtttttatga agagtatgga
    22441 acagtaccac gcggttttac ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca
    22501 gggaaagatc cagaagctta tccgacgttc aaagaatttt tagccttttt aggacaactg
    22561 gaactaccag gggcttccca agagaaaaag aatcggaaag aagaaatgga gtctatcgtg
    22621 gaatccttat gtgagactta tggcatgatt tttgatggtc atagtacgat tcgacacctt
    22681 gaccaacaac agttggtctt ttttgacatt gactctatta caggcctaga tcgaggggta
    22741 caacaatgtc agatgtacat ggccatgacg ttgatttgga atcaggcatt gattcaagga
    22801 cgaagacaac gacgcttaat taaagaaaaa caaatggaag aacaagactt caaacgcttc
    22861 ttggcgatga ttgatgagtg cca
//
LOCUS       DADVXB010000034        22647 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.034, whole genome shotgun sequence.
ACCESSION   DADVXB010000034 DADVXB010000000
VERSION     DADVXB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.034"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            131..3658
                     /locus_tag="KB902_001026"
     CDS             131..3658
                     /locus_tag="KB902_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBB6807868.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="KB902_001027"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="KB902_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBB6807869.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDKQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="KB902_001028"
     CDS             7446..7787
                     /locus_tag="KB902_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6807870.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="KB902_001029"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="KB902_001029"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBB6807871.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /locus_tag="KB902_001030"
     CDS             9144..11564
                     /locus_tag="KB902_001030"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBB6807872.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="KB902_001031"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="KB902_001031"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBB6807873.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="KB902_001032"
     CDS             12998..13735
                     /locus_tag="KB902_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6807874.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="KB902_001033"
     CDS             13749..14564
                     /locus_tag="KB902_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6807875.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="KB902_001034"
     CDS             14577..15224
                     /locus_tag="KB902_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6807876.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="KB902_001035"
     CDS             15240..15896
                     /locus_tag="KB902_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6807877.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="KB902_001036"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="KB902_001036"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBB6807878.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="KB902_001037"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="KB902_001037"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBB6807879.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="KB902_001038"
     CDS             18238..18756
                     /locus_tag="KB902_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6807880.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /locus_tag="KB902_001039"
     CDS             18863..19363
                     /locus_tag="KB902_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6807881.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="KB902_001040"
     CDS             complement(19643..20563)
                     /locus_tag="KB902_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBB6807882.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20728..21741
                     /locus_tag="KB902_001041"
     CDS             20728..21741
                     /locus_tag="KB902_001041"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBB6807883.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="KB902_001042"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="KB902_001042"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBB6807884.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         7541 a         3949 c         4824 g         6333 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagataagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgag cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgta
//
LOCUS       DADVXB010000035        22625 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.035, whole genome shotgun sequence.
ACCESSION   DADVXB010000035 DADVXB010000000
VERSION     DADVXB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.035"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            3..815
                     /locus_tag="KB902_001043"
     CDS             3..815
                     /locus_tag="KB902_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBB6807885.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="KB902_001044"
     CDS             812..1612
                     /locus_tag="KB902_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBB6807886.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="KB902_001045"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="KB902_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBB6807887.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="KB902_001046"
     CDS             3109..4818
                     /locus_tag="KB902_001046"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBB6807888.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5030..9388
                     /locus_tag="KB902_001047"
     CDS             5030..9388
                     /locus_tag="KB902_001047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBB6807889.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9533..10006
                     /gene="rimP"
                     /locus_tag="KB902_001048"
     CDS             9533..10006
                     /gene="rimP"
                     /locus_tag="KB902_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBB6807890.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10029..11204
                     /gene="nusA"
                     /locus_tag="KB902_001049"
     CDS             10029..11204
                     /gene="nusA"
                     /locus_tag="KB902_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBB6807891.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11226..11519
                     /locus_tag="KB902_001050"
     CDS             11226..11519
                     /locus_tag="KB902_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBB6807892.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11516..11827
                     /locus_tag="KB902_001051"
     CDS             11516..11827
                     /locus_tag="KB902_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBB6807893.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11840..14146
                     /gene="infB"
                     /locus_tag="KB902_001052"
     CDS             11840..14146
                     /gene="infB"
                     /locus_tag="KB902_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBB6807894.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14173..14520
                     /gene="rbfA"
                     /locus_tag="KB902_001053"
     CDS             14173..14520
                     /gene="rbfA"
                     /locus_tag="KB902_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBB6807895.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14677..14850)
                     /locus_tag="KB902_001054"
     CDS             complement(14677..14850)
                     /locus_tag="KB902_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807896.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15298..17660
                     /locus_tag="KB902_001055"
                     /pseudo
     CDS             15298..17660
                     /locus_tag="KB902_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            18028..18951
                     /gene="truB"
                     /locus_tag="KB902_001056"
     CDS             18028..18951
                     /gene="truB"
                     /locus_tag="KB902_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBB6807897.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18955..19896
                     /gene="ribF"
                     /locus_tag="KB902_001057"
     CDS             18955..19896
                     /gene="ribF"
                     /locus_tag="KB902_001057"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBB6807898.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20248..21033
                     /locus_tag="KB902_001058"
     CDS             20248..21033
                     /locus_tag="KB902_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6807899.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21046..21897
                     /locus_tag="KB902_001059"
     CDS             21046..21897
                     /locus_tag="KB902_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBB6807900.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(22021..22473)
                     /locus_tag="KB902_001060"
     CDS             complement(22021..22473)
                     /locus_tag="KB902_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807901.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
BASE COUNT         7673 a         3957 c         4946 g         6049 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagc agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtggtca cagcagccgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcagtaatag gagtttacga gctgtttcgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtattgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactatttaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt tcgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcacga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcctgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 cggataaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcgta ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta caccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg attatcggag acggtggcgc aatgggcggg
     3721 aaagactcaa aagaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgcggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tactttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaatg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat cttcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaactgg
     4501 ccaaaaggaa ttgcgccatt tgatttgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaaacc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg tgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctgcattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgagtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cacatccagc taggacgaaa
     5701 tattccagcc gatgaaccaa cgacaccaat gatcagtatc gttgaagaag aacgaagagt
     5761 cacacttgag gggtacgtat tcgacaaaga agtcagagaa ctacgttcaa aacgcaagat
     5821 cttgactttg aaaatcacag attatacttc atcatttatc gtcaaaaaat tctcgaacgg
     5881 cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt agctggttaa aggtacgagg
     5941 aagtattcaa gaagatacgt ttgtccgtga tttggtcatg aatgcgcaag atatcataga
     6001 agtcaaacat acacctcgca aagattatgc tcctgaaggg gaaaaacgag tagagcttca
     6061 tgttcatagc aatatgagta cgatggatgc aacaaacagc atctctgatc ttgtggcaca
     6121 agcagggaaa tggggacacc gagctatcgc cattacagac cacggtggtg cgcaagcctt
     6181 tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa atcttatacg gcgtggaagc
     6241 gaatgtcgta gatgatggtg tcccaattgc ttataatgat gcacatgaag cattgagtga
     6301 agccacatat gtcgtatttg acgtggaaac gacaggattg tctgcagtat atgacacgat
     6361 catcgagcta gccgcagtca aaatgtataa aggaaatgtg atcgaaagct ttgatgaatt
     6421 tatcgatcca ggacatcctt tgtcacgaac aacggtagat ctgactggta tcacggatgg
     6481 aatggttcga ggatcaaagt cggaagaaga agtattgcgg atgttccttg aattttcaaa
     6541 agatacaatt ttggtagccc acaacgcggc ttttgatatg gggttcttga atactagcta
     6601 cgcaaggtat ggtattcctg aagcggccaa tccagtcatt gatacgttgg aattagctag
     6661 atatctgtat cctcaattca aacgtttcgg attaggtgtg ttatctaaaa aatttggtgt
     6721 cagcttggaa cagcatcacc gagcaatcta tgatgctgaa gcaactggtc acttagcatg
     6781 gatctttgtg aaagaggcaa tggacaatca taacatgctt tatcatgatc agctaaatga
     6841 gcatatcgga gaaggagatt cttacaaaag ggctcgacct ttccatgtaa cgattttagc
     6901 aaaaaatcag gcaggactga aagatttgtt caaactgatt tcaatgtcga atgtcgaata
     6961 cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa aagatgcgtg aaaatctatt
     7021 gatcggctca gcttgtgata agggagaaat attcgaagcc atgatgcaaa aaggggtaga
     7081 agaggcaaga aaccgagcaa aattctacga ttatattgaa gttatgccaa aagcggtcta
     7141 tgcgcctttg atcgagcaag aattggtaaa aaatgaacat gatttggaag aaattatcca
     7201 aaatttggta gaaatcggaa aaagtttgga taaaatcgtt gttgcaacag gtaatgtaca
     7261 ttatctgaac gaagaagatg ccatttaccg aaaaattttg atcaattcta tgggcggagc
     7321 gaatccgttg aatcgtcata gtttgccgga tgtccatttc cgaacaaccg atgagatgct
     7381 aactgcattt cactttttag gggaagaaac agcgaaagag atcgtagtag aaaatacgaa
     7441 taaaatcgca gatatctgcg aagaagtgat tccagtcaaa gatgaacttt atacaccgaa
     7501 gattccaggt tcagaagatg aaatatcaga attgagttac acaaaagcaa aacaaatgta
     7561 cggagatccg ttacctgaga tcattcaaaa acgattaaaa aaagagttga attctattaa
     7621 tggtaatggc ttctcggtta tttatctgat cgcccaaaaa ctagtgcata aaagtaatga
     7681 agatggctat ctagtaggtt cacgtggctc tgttggctct agctttgttg cgacgatgac
     7741 aggaatcact gaagttaatc cgttagcccc tcattattat tgtccagagt gccaatattc
     7801 cgagtttttt gaagatggta cgtatggttc tggatttgac atgccagaaa aacaatgtcc
     7861 aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt ccatttgaga catttttagg
     7921 attccatgga gacaaagtgc ccgatattga tttgaacttc tcaggtgatt atcaagcaga
     7981 agcccataac tatacgaaag tattgtttgg cgaagactat gtttaccgtg ccggaacgat
     8041 tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa ggatacgaaa gggacaataa
     8101 tctgcagttt cgaagtgcag aagtcgacag attagcaaaa ggcgctactg gagtcaaacg
     8161 gacaaccggc cagcatccag gggggatcat cgttattccc gattatatgg atgtctatga
     8221 ttttacgccg atccaatatc cagcagacga tcaaaattcg gaatggaaaa cgactcattt
     8281 tgattttcac tcgattcacg ataatgtatt gaaattagat attctagggc atgatgaccc
     8341 aactgttatt cggatgcttc aagatttatc agggatcgat ccacaaacga tccctacgga
     8401 tgacccggaa gtgatgcgga tatttgccgg tcctgaagta cttggagtaa gtcaggaaca
     8461 aatttattcc aaaacaggga cattaggtat tccagaattc ggcactcgtt ttgttcgagg
     8521 gatgctagaa gaaacgcatc ctacaacttt tgcagaacta ctgcaaattt ccggactatc
     8581 tcatggtaca gacgtatggt taggaaatgc ggaagaattg attcgacgag gagatgcgac
     8641 actggcggaa gtaatcggct gtcgtgatga tattatggtt tatttgatcc atgctggatt
     8701 agatagcggg atggcattta aaatcatgga aactgttcgt aaaggacaat ggaacaagat
     8761 ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa gaaaataatg tgcccgactg
     8821 gtatatcgat tcttgttcaa aaatcaaata tatgtttccg aaagcccatg ctgcagctta
     8881 cgtattgatg gctcttcgtg tcgcttattt caaggtttat ttccctattt tgtattactg
     8941 tgcatacttt tctgtacgtg cagacgactt tgatctagtc tccatgtgca aaggaaaaga
     9001 tgctgtgaaa caagcaatga aagaaatcac ggacaaagga ttagatgctt ccgtaaaaga
     9061 aaagaatcaa ctgacagtgc tggagttagc caatgaaatg ctggaacgag gattcaaatt
     9121 tggaatgatt gatttgtata aatcggatgc cgttaacttt gttattgaag gtgatacgtt
     9181 gatcgcacca tttagagctg tcccaagttt gggaaccaac gtggcaaaac aaatcgttga
     9241 agcaagaaaa gacggtccat ttttatccaa agaagatctt gccacccgcg gtaaagtttc
     9301 aaaaacattg atcgaatata tgaacgacaa tggcgtattg aaagatctac cagatgaaaa
     9361 tcaattatcg ttattcgata tgctataagc atctgttttc ctgtctgctt gtaattttaa
     9421 gcagagtatg gtatagttct tataggtaat gatactaact gtgagtgagc ggatttttcg
     9481 ctcactcttt ttaatggaat tacgcactta attttttaag gaggcgaaac ttttgagtag
     9541 cgtcgttgaa acagtcacag aaatggtgac accgatttta gatgaacaaa attttgaact
     9601 tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc ttacgagtat ttattgacaa
     9661 agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt gagaaactga gtgaaaaact
     9721 tgatgcagca gatccagatc cgattcctca agcttatttc ctggaggtat cctccccggg
     9781 agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag gcacttggtg attatgtcca
     9841 tgtctcctta taccaaccag tagatggcga aaaacaatat gaaggatttc ttcaatcatt
     9901 tgatgctgaa cagcttacat tgaaaatacg cataaaaaca cgagaaaaag aattgacttt
     9961 tgaccgaaaa aatattgcaa aagctcgctt agctatccaa ttttaatcac ggagaggaat
    10021 cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc tttagaagct gaaaaaggga
    10081 tctcaaaaga aatcgtgatc gatgctttag aagcagcatt ggtttctgca tacaaacgtc
    10141 actatggcca agcacaaaac gtcgaagtgg aatttgatca gaaaaaagga aagatccatg
    10201 tctatgcggt aaaagaagta acggaagaag tgatggattc acagttggaa gtctcattga
    10261 aagatgcact tttaatcaat ccagcatatg agatcggtga tacgatccgt tttgaagtaa
    10321 caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa acaagttatt ttacagcgtg
    10381 tacgtgaagc agaaagaacg attatttata acgaattcag tgcttatgaa aaagacatca
    10441 tgcaaggaat cgtcgaacgc caggataaac gttatattta tgtcaatctt ggtaaaattg
    10501 aggcagttct ttctaaacaa gatcaaatgc caaatgaatt ttatcaacca catgatcgaa
    10561 tcaaagttta tgtttcccga gtagaaaata cgtctaaagg tccgcaagta tttgttagcc
    10621 gcagccatcc agacctattg cgccgcttat ttgagcaaga agtaccagaa gtctatgatg
    10681 gaatcgttga aattgtcagc atcgcccgtg aagctggcga tcgttcaaaa gtggcagttc
    10741 gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt cgggccaaag ggacaacgag
    10801 ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga tatcgtcgaa tggaatgaag
    10861 atccagctgt attcattgca aatgcattga atcctgcaca agtcatggat gtgatcttcg
    10921 atgagacaaa tccaaaggcc tgcacagttg tcgttccaga ctaccaatta tcgctagcaa
    10981 tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt gactaaccat aaaatcgata
    11041 tcaaatcaga atctgacatg acggaatttt atgaaaatca agaacaacaa aaagaaacag
    11101 aagaactgca tgatgaagca atcgttcagt cagatttaac agacgatgaa tatgaaacaa
    11161 ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc ttaactttag taaggaggca
    11221 aagagatgaa acaaaggaaa attcctttac gcaaatccgt ggtttcaggt gaaatgaaac
    11281 ctaaaaaaga gatggtccga atcacccgtt caaaagaagg ggaagtatcg atcgatccaa
    11341 ctggaaaaat gcctggacga ggagcgtatg tctcacttga gccggaagaa gtacaacaag
    11401 cttgggataa aaaaattctc gatcgagtac tcgaaacaac attaacagat gagttttatc
    11461 aagaacttct tgactatgtc actcaccaaa aagcacgtaa agagttattt ggaaaatgaa
    11521 tacagttaat cggcaaaaag ccatgaatct catcggtcta gcgatgcgcg cgggaaaact
    11581 aatcacgggt gaagaactga ccattgctga aatccgcaaa caaaaagcaa aattggtgtt
    11641 tgtggcaacc gatgcaagcg agaatacaag aaaaaagata aaagataaga gttcatatta
    11701 tgaagttcct tgctttgagc tattttctga agcagaaatc acgcagatga tcggaaaacc
    11761 tcgcaaggta ttcggaataa tggatgccgg atttgcgaag aagaccaagg agctaattga
    11821 aggttaggaa ggtgattgca tgggcaacaa aagaatctat gaattagcaa aagaactcaa
    11881 aaaatctagt aaagacgtcg tggaaaaagc acaacaactt ggcatcgatg tgaaaaacca
    11941 tatgggtgcg attactagca atgatgagaa gaaattgcaa caagcgttca aaaacccaag
    12001 cacgaaacaa caagctgcac aacaagcaag cagaaaacca gccaatcaac agccgaacga
    12061 tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat aaaaataacc gcagttatca
    12121 agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa aaaccaacaa caaaccaaaa
    12181 taatacggga aataccagca gccaaaatcg tcaaggaacg agccaaggcg gcaatcaaaa
    12241 ccgtactaac aataacaaca aaccaaacaa taacaatcgc ggcaaattta ataataataa
    12301 ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag caacaatcaa ctaaaccagc
    12361 tgtaccacca cgcaaattcc gtgaattgcc agatgtatta gagtatactg aaggtatgaa
    12421 cgtagcagat attgcgaaaa aaattcatcg tgagccagca gaaatcatta aaaaattatt
    12481 tatgcttggt gtcatggtca atcaaaacca agcactggat aaagatacga ttgaactgtt
    12541 agcgacggac tatggcatgg aaccacaaga aaaagtccaa gttgacattg ctgatatcga
    12601 taaattcttc gaggcagaag aagtcgatcc agataaatta gtctcacgtc cgccagtcgt
    12661 aacgattatg ggacacgtag accatgggaa aacaacttta ttggatacat tacgccattc
    12721 acgtgtaaca agcggcgaag ccggcggaat cacacagcat atcggtgcct accagatcga
    12781 tattgatggt aaaccaatca ctttcttgga tacaccagga catgcggcct ttacaagtat
    12841 gcgtgcacgt ggagcaagta tcacagatat cacgatctta gttgttgctg cagatgatgg
    12901 cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa gctgcaggcg ttccaatcat
    12961 cgtcgctgta aataaaattg ataaaccagg tgcaaaccct caacatgtta tgcaagaatt
    13021 aagtgagtat gagttaattc ctgaagcatg gggtggagaa acgatctttg ttgagatctc
    13081 agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg atcctgttag tcgcagaagt
    13141 agaagattta aaagcagatc caacacaacg cgcaatcgga acagtgatcg aagcacgtct
    13201 tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa gaaggaacac ttcatgttgg
    13261 tgacccaatc gttgtcggta atacttacgg acgtgtccgt gtaatgacaa acgatcttgg
    13321 ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa atcactggct tgaatgatgt
    13381 acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa aagacagcac gtgcagcggg
    13441 tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct gccacaagcc gtgtgacttt
    13501 ggataactta tttgaaagcc tgaaagaagg cgaattgaaa gaagttaacg taatcatcaa
    13561 agcagatgta caaggttcag cagaagcact ggctgcatca ttgaagaaga ttgatgtgga
    13621 aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca atcaatgaaa gtgatgtaac
    13681 cttagcagca gccagcaacg ctattatcat cggtttcaac gttcgtccta caccgcaggc
    13741 aaaagtgcaa gctgatactg aagaagtcga tattcgtctt caccgtatca tctataaagc
    13801 catcgaagaa atcgaaactg cgatgaaagg gatgctagac cctgaatttg aagaaaaaat
    13861 caccggtcaa atgatcgttc gtgaaacctt caaagtttct aaagttggta cgattgcagg
    13921 tgcctatgta acagaaggat atattcgtag agatagcggt gtccgtgtaa tccgtgacgg
    13981 aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga ttcaaagatg acgtgaaaga
    14041 agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa ttcaatgaca tcaaagtaga
    14101 tgacgtaatt gaaggattta tcatggaaga agtcaaaaat gactaaaaac tgataaaagg
    14161 aggccaatca ttatggctaa ctaccgtgac cgccgagtcg gtcaagaaat cttaaaagaa
    14221 gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg tggagaacgt aacgatcaca
    14281 gatgtgaaag ttacggggga cttacagcaa gcaacgatct attacagcat tttatctgac
    14341 ttagcatcag ataagaaaac agcacaagat ggattgaata aagcatcagg attgattcgt
    14401 cgagagttag ggcacaatct aagtatttat aagacacctg aattgttctt tgaacttgat
    14461 gaatcagttg tctatggcaa ccatatcgat gaattgcttc gcgacttgaa caaagactaa
    14521 tcaaaaactc ccgcaaatcc tgtgaaatca ggggttgcgg gatttttttg ttttcattaa
    14581 gacgtattac ctaagagttc catgacttta gtcttgcggc gtgtcagcta accaaaaaag
    14641 agaaaaagaa aagtaaaaaa ttcgactttc ttttttctag tagtatataa atttttgcat
    14701 atagataaag atcaagatac cgataacgga agctagattg taatctattt tagtgacagt
    14761 caggtatagc caagtaacta gaagatcagt ggaacctgca ccataaaagt ttgagtttgt
    14821 cggtccgttg acagttaaaa gaaaaatcac gttgaagtta ttgatatttc cgattacgcc
    14881 gcttcgattt ggtcacgatc caaattttgg ataatccctg tagaaattag catagtagct
    14941 gggataccaa ttcacatatt gacaaagata acagagactt ttacataaaa cggatcaatc
    15001 aggaaaggaa ttgctcgatc cagccccagt tttccagcaa tgtgttaact ggcccagcgt
    15061 cattcagcaa attatgcatg atgaggagcg aaatgaactg cggaacagcc attgtgataa
    15121 cgacaagttt tttggatcaa tgtaaaaaac gtcagcgaaa ggaaaaattt cgtggttttt
    15181 tatacctgtt catttggcta gatataaaat ccaaacaaat gaacagaagt gcttattagg
    15241 tttcaattgg gagtatctgc gctagaataa gagtaataat gaaaaggagt gttatgtatg
    15301 gattattcta gtaaagaata ctttgataaa atgacggctt ggtggcgtgc tgctaattat
    15361 ctttctgttg ggcaacttta tcttaaagat aaccccttac tgagacgtac actgaaaccc
    15421 gaagatgtca aaaaacatcc aatcggtcat tggggaacga ttcctggcca aaattttatt
    15481 tatgtccatt tgaaccgagt catcaataaa tatgatttga acatgtttta tattgaaggg
    15541 ccaggacacg gcggacaagt catggtatcg aatgcttatt tagatggaag ttacacagag
    15601 atctatccag aagtaacgga agatgagaca ggaatgcaaa aattattcaa acgattttca
    15661 tttcctggag gcattgcttc tcatgcagca ccagaaacac caggttctat ccatgaaggc
    15721 ggagagcttg gatactctct ttcacatgca gtcggagctg tattagacaa tcctgaagta
    15781 atctctgctg tcgtgattgg tgatggtgaa gcagaaaccg gtcctttagc tggaagctgg
    15841 ttctcaaatg tctttatcaa tccagtgata gatggagctg ttttaccgat ccttcattta
    15901 aatggtgcaa aaatagccaa cccaacgatc ttggcacgta aatcagatgg agaattagca
    15961 aattacttta acggacttgg ctgggaacct ttctttattg aaggaaatga ttcagaaaaa
    16021 ttaaatcctg ttatggctga aaaaatggat caagcaatcg agaaaattaa atccatccaa
    16081 aaagaagctc gcctgaagac agcaacagat gtcgtgatgc caaaatggcc agtattgatc
    16141 gtacgcacac caaaaggatg gaccggtcca aaagaatggg acggggaacc aattgaagga
    16201 accttccgag cacaccaagt accgattcct gtagatcaag aacatatgga tcatgcagat
    16261 gctttactcc gttggctgaa atcctatgaa ccagaaaaat tatttgatgc acaaggacgt
    16321 attttagaag aaatcagaga aatcgcgcct actggtgacc aaagaatggc aaaaaatcct
    16381 atcaccaatg gtggaatcga tccaagaccg cttattatgc cagattggaa aaaatatact
    16441 ttgcaatttg aaaaaccagg ctccgttaaa gcagaagata tgaccgaact tggtaaattc
    16501 gttcgcgaga tcattgagaa aaatccagaa aatttccgta tatttggacc agatgaaaca
    16561 aaatcaaacc gattgaatca agttttcaaa acgacaaatc gccaatggat ggaaaaaatc
    16621 gaaccagaaa atgatgaatg gctttcgcca tctggtcgcg tcatcgacag tcaattatcg
    16681 gaacaccaag atgaagggtt cttagaaggg tacgttctga ctggacggca tggttttttg
    16741 caagttacga atcattcttg cgagtggttg actctatgtt gactcagcac ttcaaatgga
    16801 tgcggaaatc acatgacctt tcttggcgaa atgattatcc ttcgctaaat ctcattgcaa
    16861 gctcaacagt cttccagcaa gatcacaatg gatatagcca ccaagatcca ggaatattga
    16921 cacatttggc agaaaagaag gcggagttca tccgtgaata tctgcctgcg gatgcaaata
    16981 cattgctcgc agtcatggat aaagcattcc gctcgtcaga aaaaatcaat ttgatcatct
    17041 cttccaaaca tccgcgtgct caattttact cagcagaaga agcagccgtc ttagtgaatg
    17101 aaggcttgaa aatcattgat tgggcttcga cagcaaaaga ggaggaacct gaattggtca
    17161 ttgctgctgc aggaacggaa tctaacttag aagcattagc agctgtaact ttgctgctgg
    17221 aagaattccc aaaactaaaa attcggttca tcaatgtcgt agatttattg aaattacgtc
    17281 atccaagtca agatccgcgt gggttgagcg atgaagaatt tgatcaatat tttacaaaag
    17341 acaaaccgat cttatttgct ttccacggtt atgaaacatt ggtccgcacg attttctttg
    17401 atcgtcataa ccatcattta atgattcatg gctacaaaga aaatggagat atcacgacac
    17461 catttgacat gcgtgtagta aatgaacttg atcgttatca tttggcaaaa gacgcagctt
    17521 taaaaatcaa aggaagtcaa gcagaagatt ttgcgaaaaa aatggatcag aaattacaag
    17581 aacatcaaaa ctatattcgt gaaaatggta ttgatctgcc agaagtattg gattggaaat
    17641 ggaaaaatct tgaccaataa aatgataaaa tcgatcccgc aaaatagaat tttttacatt
    17701 gattaagaaa ctgaaaaaat aaataaaaaa aacggaaaaa agactggaag aatggccagt
    17761 cttttttttc gtttttggga agtgaaaaac aaactattta cctgtaagcc acccataaat
    17821 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaagcataa
    17881 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
    17941 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
    18001 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat tacctttatg gaaagaacgc
    18061 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
    18121 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
    18181 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
    18241 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
    18301 gatatgtctt tatctgaaaa aaaaatagat gaagtgatgg cttcatttat tggtgagatc
    18361 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
    18421 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
    18481 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
    18541 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
    18601 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaggat
    18661 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
    18721 ctgccaatag aaaaaggagt ggaacggttc aaacgagtag atattactga tgaagtatgg
    18781 cagaaagtaa aaaacggtat gagacttgat tatactgtat ttgcgctccc agaaatgccg
    18841 tcagaagaaa ttgctttgtt ttataaagga aaagttgtca gtatttatca gccaaacccg
    18901 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
    18961 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
    19021 gtgctgggat ttttcgacgg cgtgcatatc ggacaccaga aagtcataaa gacaggtatg
    19081 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatct
    19141 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
    19201 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
    19261 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
    19321 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
    19381 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
    19441 ggtgaaaaaa tcagctctac ccgtattcgt ggattactag acagcggaca agtaaaagaa
    19501 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
    19561 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac ggttcatttg
    19621 cctaaagaag gtgtttatgt gtcggaaata aaaattgggg aaacatggta tccagccatg
    19681 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agagttgtat
    19741 attttggact ttaatcaaga tatctatggt gaacatgtcg cggtacgctg gaatcaattt
    19801 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaggaggat
    19861 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
    19921 ttatgtataa ctagcaatta caataaaatg ggtgataaat aagcccagga aaggggctgt
    19981 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
    20041 cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct ttctttatag
    20101 aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat ttgctttaga
    20161 ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg taataacagg
    20221 tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa agtcgcagta
    20281 gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg gaaagaaaaa
    20341 atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc agtcaaagca
    20401 atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc tgaagaagga
    20461 atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt ttgggttaat
    20521 aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga ttgggaaaga
    20581 gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt aaattacttt
    20641 acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga acagatccca
    20701 tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt taccgaaacg
    20761 gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc tggtgctatc
    20821 cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact cttggaaagt
    20881 atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc tgcatggttg
    20941 gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg tgggatgact
    21001 ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg tttattgatt
    21061 gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa gattggtggc
    21121 agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg cttactcgtt
    21181 caattattcg cttctccagc tggtatttca gtgactacat ttttgattag tttactttct
    21241 ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt gattggtgtt
    21301 tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt gattggtgtc
    21361 ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc agcaatcatt
    21421 cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa aaaaggcggt
    21481 atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt atacagtgca
    21541 ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat gatcggtgtc
    21601 tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc tgaagacaag
    21661 agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc ttatattttt
    21721 tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa cgtagttatc
    21781 tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga aaaaaaatta
    21841 acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt tatttgagga
    21901 taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac agtaagtact
    21961 tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct ttttaattgt
    22021 ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc attgactaaa
    22081 gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt ctttataaag
    22141 atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt actggactaa
    22201 ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga aacgcatcgt
    22261 gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg cttgatctcc
    22321 gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa cctttgttcc
    22381 ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac ctaattgttc
    22441 ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt gaatggttct
    22501 actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt taattaaggt
    22561 cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa ttcgttctct
    22621 cctaa
//
LOCUS       DADVXB010000036        22414 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.036, whole genome shotgun sequence.
ACCESSION   DADVXB010000036 DADVXB010000000
VERSION     DADVXB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.036"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            424..873
                     /locus_tag="KB902_001061"
     CDS             424..873
                     /locus_tag="KB902_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6807902.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            930..2348
                     /locus_tag="KB902_001062"
     CDS             930..2348
                     /locus_tag="KB902_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6807903.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            2348..3208
                     /locus_tag="KB902_001063"
     CDS             2348..3208
                     /locus_tag="KB902_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBB6807904.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            3382..4155
                     /locus_tag="KB902_001064"
     CDS             3382..4155
                     /locus_tag="KB902_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6807905.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            4302..4667
                     /locus_tag="KB902_001065"
     CDS             4302..4667
                     /locus_tag="KB902_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBB6807906.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(4815..6023)
                     /locus_tag="KB902_001066"
     CDS             complement(4815..6023)
                     /locus_tag="KB902_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6807907.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(6042..6320)
                     /locus_tag="KB902_001067"
     CDS             complement(6042..6320)
                     /locus_tag="KB902_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807908.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            6474..7169
                     /locus_tag="KB902_001068"
     CDS             6474..7169
                     /locus_tag="KB902_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6807909.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(7611..8408)
                     /locus_tag="KB902_001069"
     CDS             complement(7611..8408)
                     /locus_tag="KB902_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBB6807910.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(8405..9589)
                     /locus_tag="KB902_001070"
     CDS             complement(8405..9589)
                     /locus_tag="KB902_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6807911.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(9614..10861)
                     /locus_tag="KB902_001071"
     CDS             complement(9614..10861)
                     /locus_tag="KB902_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6807912.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            11076..12821
                     /gene="dnaX"
                     /locus_tag="KB902_001072"
     CDS             11076..12821
                     /gene="dnaX"
                     /locus_tag="KB902_001072"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBB6807913.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            12841..13155
                     /locus_tag="KB902_001073"
     CDS             12841..13155
                     /locus_tag="KB902_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBB6807914.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            13180..13776
                     /gene="recR"
                     /locus_tag="KB902_001074"
     CDS             13180..13776
                     /gene="recR"
                     /locus_tag="KB902_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBB6807915.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            13840..14484
                     /locus_tag="KB902_001075"
     CDS             13840..14484
                     /locus_tag="KB902_001075"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBB6807916.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            14499..14828
                     /locus_tag="KB902_001076"
     CDS             14499..14828
                     /locus_tag="KB902_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBB6807917.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            14842..15780
                     /gene="holB"
                     /locus_tag="KB902_001077"
     CDS             14842..15780
                     /gene="holB"
                     /locus_tag="KB902_001077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBB6807918.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            15816..16640
                     /locus_tag="KB902_001078"
     CDS             15816..16640
                     /locus_tag="KB902_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBB6807919.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            16633..16980
                     /locus_tag="KB902_001079"
     CDS             16633..16980
                     /locus_tag="KB902_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBB6807920.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            17049..17921
                     /gene="rsmI"
                     /locus_tag="KB902_001080"
     CDS             17049..17921
                     /gene="rsmI"
                     /locus_tag="KB902_001080"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBB6807921.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            18030..19151
                     /gene="dinB"
                     /locus_tag="KB902_001081"
     CDS             18030..19151
                     /gene="dinB"
                     /locus_tag="KB902_001081"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBB6807922.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(19205..19807)
                     /gene="nrdG"
                     /locus_tag="KB902_001082"
     CDS             complement(19205..19807)
                     /gene="nrdG"
                     /locus_tag="KB902_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBB6807923.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(20122..22311)
                     /gene="nrdD"
                     /locus_tag="KB902_001083"
     CDS             complement(20122..22311)
                     /gene="nrdD"
                     /locus_tag="KB902_001083"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBB6807924.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
BASE COUNT         7107 a         4080 c         4681 g         6546 t
ORIGIN      
        1 gtttagcaga ctatctgata gggatagtct gtttttttat gttttttgcc aatttaaaac
       61 ttcgtttgat gctgaaaaag tcgtaggatc ataatgcaca aaacaatgaa aaactagtat
      121 atagttttaa ttatccactt gataaaaaca ccttatatta acgaaatgaa gaggggttat
      181 ttcgaagtaa aaaaccattt acctaaaatt agaagctaag ctttcctttc aaggaaggct
      241 ttttgttttg ttatagactt gcgattgttt gtgagctaga tcgttcattt taatgactta
      301 tacacgcgga tgatgggtct ttttcctctg ttcattcata atattgaacg gtacagctag
      361 cgatgctata ctgacctcag ttccaagaaa acgttaacat tttttgtggg ggagaggttt
      421 tttatgaggt ttgatcaatt gatcgcagaa gaactgattg ttttcgatcc atcgatagat
      481 tcaaaaggat cattatttga gcgaataggg gatgtgttga aaaaaacaaa taaggtaaga
      541 aatgttcaaa aagtcgttaa ggcactattc aaacgagagg aggagatctc cacaggaata
      601 gaagatggat ttgggattcc ccatgcaaaa agcaaatatg tgacaaaacc agcactgtgt
      661 ttttttcata cagccaaatt aacggactat agcgggatag atgaaatgcc aattgaatat
      721 atttttgcca tcgtagttcc tgaaaaatca gcagatatgc atctagagat tctcagcaca
      781 ctctccagac gattgatgaa tgcagatttt agaaagggaa taaaagaagc cactacgcca
      841 gcagatatca tcagacagat tagtcaagaa tgaaaatagt agagtctttg tccgagtatc
      901 gatagtgaag aaaaaggagg aaaataatca tgaaaatcgt tggtgtaact gcttgcccga
      961 ctggaattgc tcatacttat atgtcggcag aaaaattaga agtaacagca agaaatctaa
     1021 accatcaagc aaaattcgaa acacaaggtg taaaaacaga aaatcagtta tctgaacaag
     1081 aaatcaaaga ggcagatgca atcattcttg cagtagataa agaaatcgaa ttggaccgat
     1141 ttgccgggaa aaaagtaaag cgtgtctcta caagccgagc aatcaaagaa ccgcaagtag
     1201 taatagacga agcattgaga gatattggcg tattcgttgt gtctaatgaa aaagaaccag
     1261 ctgcaaatga gaaaaagccg acaatctata atcatttcat gaatggtgtg aattacatgc
     1321 ttccatttgt gatcgcaggc ggaatcatca tcgcactgag ttttgccttt gggattacag
     1381 cggctgatcc caactcagca gactataatg tgttagcagc tgcattttca aggatcggag
     1441 gagatacagc gtttgccatg atggttcctg cgttaggcgc ggggattgct acatcgattg
     1501 ctggaaaagc aggttttgcc ccaggaattg ttgccggatt actggcctct acaggtggtt
     1561 caggttttct tggcggaatg attggtggcg tgctagcagg gtatatctgt gattttctgg
     1621 caaataaaat tagcgtaaaa aaagaatttt ctgctattta tcagctgatt gtcgtcccct
     1681 ttttatcgat cttaattatt gggcttttga tggtatttgt gattgaacaa ccgatcacat
     1741 gggtgttgga tgctttgaca aattggctga atagcttggg aaatacatcc gggctattgt
     1801 tcggattact tatcgggatc atgatggcag ctgatatggg tgggccgatc aataaatcga
     1861 cttcgacttt ctcgatcggt ttgatgtcag ctggagtaaa tgcaccgatt gctgcttgta
     1921 tggctgcagg aatgacacct cccctaggta ttgctttagc cactttatta ttcaaacata
     1981 aatttaccaa agaagaacgg acttcaggtc aatcatgctg gattttaggc gcttcgtata
     2041 ttacagaagg tgctataccg tttgcggtat ctgacccgat ccgcgtgata cctagtttga
     2101 tgacaggttc agcagtcgct gcagggattt ccatggcagt aggagttact tcaatggcac
     2161 ctcatggagg gatttgggtg atgctaattc caaatgttat gaacaattta cctatgtatg
     2221 tcttggcaat tgcatcaggt acagtcacta cagcctttat gcttggacta ttgaaaaaaa
     2281 cagtgaaaga gaaaaaacaa gacaagtgga cgaaaaatga aaatctaaca aatgaggtgg
     2341 aagcgtaatg ttatatacaa tgaaagagtt attgaaagtg gctaaagaga atcaatttgc
     2401 agtaccagcc ttcaatattt gcagctatga tatgatgaaa gcaatcatcg aagaagcaga
     2461 gagattagaa gcaccagtaa tcttagaaat tcatcctgat gaaatcgcct atttaagtga
     2521 tgagtttgtt gcggcagtaa gagcctatgc ttatacaagt aaactgccga tcgttatcca
     2581 cttggatcat ggcggtacga tagaagatgt cttacgggcg attcgaaacg gctattcttc
     2641 cgtgatgatc gatgcgtctt tgaaatcatt cgacgacaat gtacagatta cgaaaaaagt
     2701 ggttgcgtta gctcatgcgg taaatgtctc agtggaggct gagcttggaa cgattgggaa
     2761 taatggttct gctgaaggag gtgctgaaac aatcatttat acagatcctg atcaagcgaa
     2821 gatttttgtg aaagaaacag gaatcgatac acttgctgta gcaattggaa cagcgcatgg
     2881 cttgtatccg aaaaacagaa ctccaaaatt aaatatcgac ttactgaaag aattgaacca
     2941 acaaatcgat cttccatttg ttttacatgg cggttcaggt aatccggacg cagaagtcag
     3001 cgaagcagta aaatacggag ttgccaaagt gaatttgagc tcagatctta aaagcgtctt
     3061 tttcaatgct ttgagagaaa tattgagtga aaatccatcg atgtacgagc cgaatgcaat
     3121 ttatccagca gctaataaaa aggtacaaga agtggtcaaa cataaaatgg aaattttgaa
     3181 cacagtaggc aaggctagtt tatactaaaa ataaaaatgt gtggtcaaga gggtatgaca
     3241 atagtcttgt cataccctct taaccacaca cgatgttcag aagtagtttt ttcgaaaaat
     3301 ttcttcttat ttctcgaagc caatcacttc tgtcacaacc tcttttttcc tgttactata
     3361 taaagtaaat ggggtgattt tatgttgaat gaagtggaga atagacagca ggagattgtg
     3421 aattatctaa aaaacaacca atttgcaaga gtcaccgatt tgatcgagtt agtaaattat
     3481 agcgaagcca cgattaaacg tgaccttgtt tttctggaaa aaagtggatt gatccgtaga
     3541 gttcgcggtg gcgccatgct tattgacaat cgaaaaattg acgtgcctta cctgatgaag
     3601 atcaccaaat tagaagaaga aacagaaaaa cgtaagattg cagatacagc ttcttctttg
     3661 attcgagatg atatggtctt attcttggat tccagtacaa cctctttaca cttagtcaga
     3721 aacctagcaa gatttgatgg tttgcagatc attacgaatg gcatcgtcac agctgctatg
     3781 ttgagtgaat atacaacggc aaaagtatct gtattgggag gggcaattgt tccgaaacga
     3841 gcaacaatca acggttcaaa agcctataac gatgcattgt catattatgc ggatttagcg
     3901 ataatgagtt gtcgcgggct agatttcagc caaggagtaa cagaaactca tgaaggagag
     3961 gcaatggtca aaaaagcttt tagaaaacaa tcagaccggc ttgccgtttt agttacacag
     4021 caaaaaattg cacataaatt catgcatcaa gccattgctt ttcatgaaat cgattatctg
     4081 gtgacaagta aagaactgac aaaagaacag tatgcgaaag taaaggaaca ccatatcgaa
     4141 tgtctgtacg gataaattat tacgtgaatg ttctaagtgg cttcctcatt tttagatagg
     4201 accttatctt tgctcgcttc tctcagccga tggtataata atgaaaaggt tatcttgtta
     4261 gataatctta cttttttatc caggagaaag gagtgcagaa aatgaaacat gtgaaggcgt
     4321 tggtagtgaa ggcaatcatg atctgggcga ttctgtgggt cgtgctgaca ggtttatacg
     4381 gtgttagctt tatggattca acgattgttg gggtaattat tgtagtcatg atctatgtgc
     4441 taggggatct gttgatctta cgtaaagtag ggaacatcgc agcgacgatc gcagatgctg
     4501 gttcagctgc agttatcttg tggctctatc tatattttat gaatgataca gtcgatattt
     4561 ggatgaaagt attgattcct gctctattga tcggtgtggc agaatggttc ttccacaagt
     4621 ggttgctaag tcaaggcatc gtaccagatg aacggaaaat ggaataaatc aacagttaaa
     4681 ctattcttat cgataaatga aagctttaaa aataaataga tgtttaatta agaataatca
     4741 taaactattt ttactcaaaa aaccgctcag attattttca gatctgaacg gtttttttta
     4801 tctattcatc aagatcaaat ttcatttttc aatgattcaa tcaattcgcc ctctgcttca
     4861 tgactatgtt ttcggccatt aacaagatag agtgctgtac atatcaatgg aatgactccg
     4921 gcaatcacat acaatcctct aaatgaagta agagatttta gcatccccat caaataagga
     4981 ccaacgccta agcctaggtc taaaccaata aagtaggtag ataaagcaat actgattcga
     5041 tgttcgcgga cgatttttaa acaaacagcc tgtccatttg acataaacgt accataacct
     5101 aggccgacta atgctccaga gataagcaat gtcacactat tcgtcgttac actcagtaaa
     5161 aataatcctg ctgttaagaa taaatagcta ggatacatca cgtattgttc tcctttgaca
     5221 tcgaaaatcc ttccagtcaa tggacgtgta aatgtgatga ccaaagcata tacgacgaag
     5281 aaaaatgacc cagcagcaac taagtggatt acttttgtat aagaagataa aaatgataaa
     5341 acacttgaat aagaaagacc catcaaaaag gcaattcctg taatgaaaag tgctttcttt
     5401 tcaataaaac tattgatatt ccatgagcga agagatattt tttgttcttc agataatgga
     5461 atatttttta caggaaagac aaggcaggca atcgtaacaa agaagaccag tacaattgaa
     5521 aaccagataa tgaaacgaaa atcagtcata ttcagcaaaa tcattcctaa aaatggccca
     5581 acagcggcag ctaaactagt acttaatcca taataattga tgccttcccc ttttttagat
     5641 gcagggatat atgcagtaac gatagcattt gtagctgtag aaactgtacc gtagccgaat
     5701 ccattcaaga atcgaactaa atacaatgcc ccgatagttg gcgtataaag atatgctaat
     5761 gttgaaagga gatagaagat cgcgccgcct cttaaggtaa acttccgacc aaatagttct
     5821 aactgtttcc ccatgaataa gcgtgccagc aatgttccga tgatatagat cccagaagca
     5881 aaacctgctt ggctcaagct ggcgtgtaag gtgtcttgcg caatgactgc catgatgacc
     5941 atcaacagat aataaatcag gtagacaata aaattgatca atgtgattcc aataaaatat
     6001 ttattaaata atttcttttc catgtatgtt atacattccc cttaagctga atatgctttt
     6061 aatttttgta tttgaacttc tacatcgtga taattggatg gatagcgatc aacaagttgg
     6121 cgaataaata aatctcttgt agacataaac agatttaaaa attcttcgca ttcgtttgtt
     6181 ggattctcat ccactgcttt gatcaattcg atcgagtttt gatacgcatc atttaaaaag
     6241 actaaagaag ctttcatatc aaatcttgtt tgatatgctg tttctaatcg attaatgatt
     6301 gtgttcatcc agtaattcat gttttttccc tctattctta aaaaatttta cttctgcagt
     6361 ataacgaata aaaaaaagga aaaaaatcgc ataagtgatg gaaaaaggta cttaacaaat
     6421 gttaatatca ttagtaaaat acctttggac tttaaaaagt tttaaagtac tgtatgatct
     6481 ttttagatga aagtttggat gggggagcat cattggatag tagagtctta aaggaatatt
     6541 tggataaaaa tgattttccg attatacgca aaggatatca taaatatttg acattcgaag
     6601 ggatggaaga ttcccatacg tatatcttga aagagggaac ggtaaaagca agtgttattt
     6661 caaatgatgg gagagaattt aaccttcgct atatcaaaga tcttgaaatc gtctctcttt
     6721 taaaagacga atattcacaa ttcatcgatt cgccgtataa tattcgagtt gaatcagaat
     6781 atgcagagtt ttatcgaatc aatcgtgtgc gcttttggca aaatatcaac caagacccaa
     6841 agctacaaca ctatgtaaaa gagtattacc gctatcgtct gctttattcg atgaaaaaaa
     6901 tgcagcaaat gctattaaac ggaaagctgg gagctgtttg tacgcaactt tacgaattat
     6961 atgatttatt cggtgtgcgg acagaagaag ggatgctgat cgatttttcg atcacgaatg
     7021 aagaaatcgc caaattttgt ggcatctcaa ctgctagcag tgtaaacaga attttaaaac
     7081 aactgaaaaa agatggtatt atcaccgtta aagaccatca tatcgttatt ttgaatatgg
     7141 acttgttaga agacaatatt atcttttgat gaacaaagag gttgtgaaat cagcgttttg
     7201 acctgagtat tagagaaaca aacggaaaaa tagttcctca tattttgccg ttttttgagc
     7261 taataccgag ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta
     7321 actctgagtc acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga
     7381 cttgtgaccg aggagttggt aggagaacac cgtttaccaa gaggttgtga aaaagctgtt
     7441 ctgcatcaag taataagaag agccaagtaa aaacagtctc ttatgttttt aacttggctg
     7501 gacttatcac cgtagatgta agcttttgaa cgccgtttat ttgcaacaaa aggggctgtg
     7561 acacgatttt tgtcacagcc ctttttttgc gaacattcat ttagcaattt ttagaaactt
     7621 ctgccgccac cgccaaaagt cccgccaccg ctagaatggg tagtacttcc gccaccgccg
     7681 cttccaggag gtgggctttt ggggattctt cttgtcgtga caaaagaatt tgtcagacga
     7741 tcggtttttt cagttaattt gatactggat ttttctcgga atggatattt gtagatgcct
     7801 gatttcaatt gataacgcga aacagtcaca aaataaaaga caagactaag gataagagcc
     7861 aaaacaacag caatgatgat ttctactgtc gtcaaaacct tatagcgtgt aattttgcca
     7921 gtttcttcgt ctacacgata atgtcctcct ggaactccgt cttccacata tgttgctgat
     7981 ttagacaggt aagcttttgc agcattgtaa taggcagcat ttgtcatctg atcataaaca
     8041 tcatctaaga tcgaatcgat tctgctatca gtcaaataat cgatcatatt accagaagtc
     8101 gaaatgtaga tttcacgctg tcccatatct aatagcaata ctgagccatt ttgatcattt
     8161 ccgactgcgt ctcttaagta attatcagca aagtctcttg gttcttctga attagatgta
     8221 gtcgttacga tcaagactcg tcctttgatt ttttcattca gcttttctgc ctgttgttcc
     8281 aaagattgga tttgatctgt tgtgaataac ccagcctcat catttaccgt agctgtatct
     8341 gcatgagtag ccaccggcca gccaacactt actagcaaaa gaaagaataa aaaaaatttt
     8401 ttcatcatat caagtaacct ccgatcagaa agaggatcgc tagcccagcg aaaatcccaa
     8461 gagcggtcag tcccaatttt ttctggctga tcggcaggac accgctgacc tttcctgttt
     8521 gtccattcat tgcgtagtag tagacttttt tacttgagtc attgcttcga taagtaacaa
     8581 gccataccgg cagtaatacg taattattta cttcgtttgt gattgaagca gaagttcgca
     8641 caccggtcaa tgttgtatat ccatttgcgg tatcttttaa cagcttctct gaatagtctt
     8701 ttaattcaga ttgaatctgt gatttgattg cctcatattc gatatctctt ttttctgctt
     8761 ggaacccggc taaatactgg cttttaaaat caattgcctt atctaacggg aaaggttgca
     8821 cgccttcgac catcttttgt tgcgtatttt ttgataaggc attttttact agttctttaa
     8881 aagaaagctt gcctgctctt gaaacagcaa attgcttcgt ttctgtgtat tcgatgtcac
     8941 ctatccgcca tatgcggata actgtaccat tcgcctgcat ggcaccatct acttcagcat
     9001 ctgtagccca ataagggaaa tacacacctg tcaacttatc gatttgatcc ttattgaaaa
     9061 aagctttggg aacaaaccat tttttcttgg tccaagcgag aaatctgttg attgcttctt
     9121 ctttctcgac agcaaaagga agtactttat ttggcaagaa ttctccgctt aaacgtcccg
     9181 atagtacgac gggattatgg cagtagtaac aataagtcgc agcagttgtc gcatcagtca
     9241 cgatctctgc accacagttg ggacaaagaa aaagatctat cgctgcggta ttatctgcag
     9301 attcgtccgc tgtatctgaa aaaccgcctg cctcgtcaac cgctttgcgc tcggcttcat
     9361 tcatatcggc aagctgttct tgggctgtaa aagtaaaatc ttcggtaggt gaaggttctt
     9421 ctttgctttc ttcgccagcc atacgcgctt ctttttgctt ttgctcatat tggctgactt
     9481 cttcttctgt atagatattc aggcagtatt cgcaatgaaa tttttggtct ttgggatcaa
     9541 aagtcaacgg accgccgcaa ttaggacatt tatgtgtaag aacatccatc agctgcacac
     9601 ctttctaaat aaattaatta acggggattc ctttaaacgg tttaccacag tttggacaga
     9661 atttagggat gccgttggaa agatccacga tctcattgca ttcactgcat cgcatttgta
     9721 gcttaggctg aacgttttct acaggtttgg cagctccgca gttggaacag aattttccgg
     9781 aattttctgt cccgcaaact ggacatgtcc aagtatccgc atttccttgt gcagtttgtt
     9841 gattttgttt ttctgcttgt tgtttgattt gttcttggtt attttgagct gcttgagaaa
     9901 gataagaacc atttgcattc attcccatac ctacacccat aaagccggtc attgctcctg
     9961 cttcattttt tccggctgct tccataccac gtgcaatgga accttgcacg tatccttcac
    10021 gtacgctagg atcacctagc atcgcccctt cgttacgcat attgatcagt ttcacagaat
    10081 catcggtgta agaaatgctg gctacagcca cagaaacaat ctccatccca cgtaattcac
    10141 gccaagaatc atccaatgca gtatccatgt atttgcttaa ttccaaactc ttagatggta
    10201 cataagaaat ccgttgacca tctgcagaca tctgattgat tgctgattgt agcgctgtta
    10261 ggaattcagc taaatactgc tcattgatat cattgatttc cacttgtgtt ttgtttttag
    10321 ggattgcgtt tgtataaaat aaaatcgggt caacgacatg aatagaataa gtgccatgtg
    10381 cccgtaagaa taattctgcg ttatagaaat tgtcaaagta gttcaacggc gcgcttgtac
    10441 cgaatttgat tccctttatt tcttggagat tgatataaaa aacttgttgt ttctgcggtg
    10501 tgacgccgcc aaatttgaat cggtcaaaag tttcagcaat tgcttctttc agtgttccat
    10561 tgaacatgga aggagctgcg tcatttttaa tggtgtaata accttcctca gcggtataat
    10621 cgatgatttt tccaccatcg accaaaagca tcatcatgtt tggatagaca tggacgactg
    10681 ttccgtctgt taaaacatct tctgttcctt tacgattgga gccacgtttg tcatctttgc
    10741 ggactttgac accttttgtc atgaccgttg tatcactcat attgtctggt tcgatgactt
    10801 ctagccattg atctgccaga ccgccgccaa ccatacttgt tgctgctttg ataagaccca
    10861 taaaaaattc ctcctctgat tcagctagtg ccaaacaatt attgtttatt tattatacca
    10921 taggaagatg tgaaacttct cggactagag acggaattga aatggaaaat tgcgtattgt
    10981 ttaaatacct gaaaaagccg agaaggatag tagttttttt acctaatatc acgtataata
    11041 agagatagtg aattttttaa aaaaggggga tccttatggc atatcaagca ctttatcgag
    11101 tctggcgttc gcagcgtttc gaagacatcg ttggacaaaa agctgtgaca cagacactaa
    11161 aaaatgctat tgtttcccac aaaacctcac atgcctactt gtttacagga cccagaggaa
    11221 ccggaaagac gagtgcagca aagattttcg caaaagcaat caactgtccg aacagtaaag
    11281 acggtgagcc atgcaacgaa tgcgaaatgt gtcgatcaat tactgctggt acgcaagaag
    11341 atgtgatcga aatcgatgct gccagcaata acggagtcga agaaatccga tttatccgtg
    11401 atcgggcaaa ttatgcgcct acaaaggcag cgtacaaagt gtacattatt gatgaggtac
    11461 atatgctttc aacaggagct ttcaatgcct tgttgaaaac attggaagag ccaaaagaaa
    11521 gtgtcatatt catcttagca acgaccgaac ctcacaaaat accagctacg atcatttcac
    11581 ggactcagcg atttgatttt aaacggatca atacggcaga tattgtcgaa catcttgaat
    11641 ttatcttgaa agaatcgact atcagctatg aaccagctgc attgaatgtg attgcccgtt
    11701 ctgcagaagg cgggatgcgg gatgcattga gtattcttga tcaggcaatc tcgtttagtg
    11761 aaggaacaat tactttagat gatgccatgc aagtgacagg tagcttaact gacgaaatga
    11821 tggacagtta cttgagtgct tgcgtgaaaa aagaagtacc agaagcattg gaaacattga
    11881 accaaattct cgcagccggc aaagaatcac gtcgctttct agaggatatg ttacaatact
    11941 gccgtgactt gctgatgtat cagcaagcac ctaacctagt tgaggaacaa tcgagtacga
    12001 tcagaagtac atttacagaa ttggcacaaa ctgtttcagc ggatcagctg ttttcaatga
    12061 taaagatttt gagcgatact caaaatgaaa ttcgttttac caatagtgcc gctatttatt
    12121 tggaagtcgc tacagtcaaa cttgcacagc taccgtctgc ttctgttcct tcagcagatg
    12181 tagcatttgc agatgatcag atagtaaaac agctacaaca agagattaag gaactaagaa
    12241 acgaaatcaa ggaactacgc agtaatacag gaattgagaa tacaaaagta cagccggtac
    12301 agcaaacaaa tcataaaaaa cagacaagta cctatcgtgt accgacggaa cgagtatata
    12361 aagttctgcg ggaagcgaca agacagcatc tgaaccaagt aaaagaagta tgggaagact
    12421 tgctgatgag tctatctgtc actcagcgag caatgcttaa agcaagcgaa ccagttgcag
    12481 ctggacctac aggactagtg attgcgtttg attatgagat tgtttgtcaa agagcagcaa
    12541 atgacgaaga attgcagctt tcggtacaca acaacttaag ccgaatgatc aaagattatg
    12601 cgcctgatcc tgtttatatt acaagagaaa gctggccaga acttcgaaga aattatttga
    12661 cgcaggcaca agaagaggga acagaaaact cttttgcttc tgaagactca gaaggagaaa
    12721 tcgagttgct tcctcaagaa caagaagtac cagaagaaac acttgtagta aaagcagagg
    12781 aactgtttgg ctccgaagct gttacagtgg tagatgatta ataaaaagga gtagataatt
    12841 atgatgcgtg gaatgggcaa tatgcaaggc atgatgaaac aagtacaaaa aatgcaaaaa
    12901 gaaatggcag aagcacaaga gctgctaaat aaaacagagt ttacaggtaa agccaccaat
    12961 gaattggtca aagcggtttt tacaggcgat cgtcgcatga aagatatcca aatcaatgaa
    13021 gaagtcgttg atcctgatga tatcgagatg cttcaggatc ttgtcgtaat ggcagtcaat
    13081 gatgcgatcg cacaaattga tgtggaaact gagaaaaaat tagggaaata cgcaaaaggt
    13141 ttgccaggat tttagtttta aactgaagga gtaatgaata tgcaatatcc agaaccaatt
    13201 gcgaaactga tcgacagcta catgaaactt ccaggaatcg gtcagaaaac agcgacaaga
    13261 ctcgcctttt atacgatcga tatgaaagat gaagtagtaa atgaatttgc taaatctttg
    13321 ttaagtgtaa aacgcgattt gcatttttgt agtatctgcg gaaacatcac agaagaagat
    13381 ccctgcgaaa tatgtagaaa tccttcacgt gatcgaagcg ttatcctagt ggtcgaagag
    13441 ccgaaagatg taatggcaat ggaaaaaatg cgagaatatc acggacttta tcatgttctc
    13501 catggtgtgt tatcaccgat ggaagggaca ggtccagaag acatcaatat ttcttctctg
    13561 ttgcagcggc tgcatgatgc agatgtaaaa gaagtgatta tcgcaacaaa tgcaacaaca
    13621 gagggagaag caacagctat gtatctctca cgtctgatca aacccgcagg tatcaaagtg
    13681 actcgtctag cacatggtct gtctgtaggc tctgatatcg agtatgcaga tgaagttact
    13741 ttattgaaag ctgtcgaagg aagacgtgag ttataaattt ctaattaagt gttttttcag
    13801 atacaatata aaagcagcac aagagatggg ggcaacaatg tgaacggact atttattaca
    13861 atcgaggggc ctgatggtgc aggaaaaacc agcatcttga atgaacttta ccctcttttg
    13921 aaagaagtag caaaaacaga aatcattcaa acaagagaac caggaggcat tccgattgct
    13981 gaagagatcc gagcagtgat ccttgatcca aaaaatgatc ggatggatga acgtacggaa
    14041 gcactgcttt atgcagcagc aagaagacaa catctagtcg aaaaggttct gcctgctctg
    14101 gcaaaaggga aaatcgtttt atgcgataga tttgtcgaca gttctcttgc ttatcaaggt
    14161 gcaggccgac gcatcggcgt taccgagatt gctcggttga atgagtttgc tacagaaggt
    14221 actacgccgg attttaccct ttatcttgac gtagattcag acaccggatt aagaagaatc
    14281 aagaaaaaca gacaaaatca aatcgaccgt ttagattcgg aaggtttgga attccaccag
    14341 cgtgtacgtc atgcttactt aaagctggca gaagagaatc cggaaagaat ccacaaagtt
    14401 gatgcaagaa aaagctttga agaagtgctg caaacaagtt atcatacaat tattgaacag
    14461 tatccgcaat tttttgaaaa ctaggaaggt gaacgtttat gaaaattatt ttagcgatta
    14521 tccaagacaa agacagcaac cgtttatcaa atgaattgat tgatgcaaat atccgtgcca
    14581 caaaactatc atcgacaggc ggcttcctta aggctggaaa cagtacgttt atcgtgggta
    14641 ttgaagatga ccgtgtagaa gaagcattgg aaatcatcaa aaaaacgtgt gaatcaagaa
    14701 agcaatttgt atctacacct gttacactgg atatttcgat ggatgggggc gtcccttatc
    14761 cagtagaagt agaagtaggc ggtgccacag tcttcgtctt acctgttgaa ggattccatc
    14821 aattttagga ggagctgagc tatgaatcaa gaaataaact tggctcaaat gcaaccgatc
    14881 gtgtatcagc agcttcaacg gagttttgag catgggcgta tcgctcatgc ttatcttttt
    14941 gaaggggaga aaggaacagg aaaacatgaa gtaggtatat ggcttgcaca gcacctgttc
    15001 tgtacccaaa tgaaagacaa tctgccttgt ggaaaatgca acaattgtca gcggatcgaa
    15061 aagaaagaac atccagatgt tttggttatt gaaccggaag gacaaaccat caaagtcgat
    15121 cagatcagac gtttgcagac ggaattcagt cgcagcggtt acgaatcaag aaaaaaagtt
    15181 tttttgatca aagaagctga aaaaatgaat agcagtgcgg caaacagttt gttgaaattc
    15241 ttggaagagc cccctggaga ttttttagcg gtgttagaaa cagatgcagt aggaagaatt
    15301 ctccctacta ttcaatctcg ttgtcaagtt ctgcattttc aagaactttc gaaagaagca
    15361 ctgatccatc gattgcaaga agagcagatt ccattggaaa aagcaaaact tttggctttc
    15421 ttaacaaaca gtttaggaaa agcagttgaa atctctcaag atgaatggtt taatgatgct
    15481 aaggacttga tttatcaatg gttcgtttac ttgcaaaagc aagatactca agcctttatc
    15541 tatgtccaaa aaaaattggt aaaatcattt aaagaaaaaa cacaacagtt tacaggatta
    15601 tctgtcttga tgttttatta tcaggaagca cagcgtcaag cagtagcaaa cggcgaatat
    15661 ggcaaagtga aacagataaa ccagataatt gaacggatat tgatcgcaga gcagaaacta
    15721 cgcagcaatg tcagttttca ggctgttgcg gaacagttcg ttttgcatac gattttttag
    15781 cttgccgcaa aggatgatga tcaaggagga tggaaatggt agaagtagta ggtgtccgat
    15841 atagagatgc aggtcatatc tattattttg caccaggaga ctctgaatat gtttatagtg
    15901 acaaggtatt agtcgaatct cagcaatcct tacatattgc tactgttgtc cttcctaaaa
    15961 aagagattga tcccaatgac cttcctgaag ctatccgtcc gatcttgcat aaagcgtcac
    16021 aagctgaatt agaaaaagac aaaaaaaaca aaaaagatgc ttatgatgca ttgaaaatcg
    16081 caaaagaaaa agtgcagttg cgtgagttgg aaatgaaaat ggtcaaagcc gaatacacat
    16141 ttgatcgaaa taaattgatt ttttctttca cagcggacgg gcgaattgac tttagagaat
    16201 tggtaaaaga tctggccgct gtatttcgta ctcgtattga gcttcgacaa attggtgtcc
    16261 gcgatgaagc aaagataata ggcggaattg gtccatgtgg gcgtccatta tgctgttctt
    16321 cttttttagg cgatttcgtg cctgtatcaa tcaaaatggc aaaagatcaa agtttatctt
    16381 tgaatccaac aaaaatttcc ggtttatgcg gacgcttgat gtgctgtctg caatatgaga
    16441 gcgaagaata cgagacagcg aaaaaagaac tccctgactt tggaaaagta attgctacac
    16501 ctgatggtaa agggaaagtc gtagggttga atctgcttag ccgtatcgtt agtattcggc
    16561 tgactggacg ggaaaatcct gtcgaatatg aatgggatga attgaaagaa tttatccaag
    16621 taggtgagat gaatggataa gagatcatta tacgacggat tgaatcaatt agaatcagag
    16681 ttgagaaata cattaacaga acttgttgaa atgaagcatg ctttgcatga gatcgtagaa
    16741 aaaaatacaa ctttggagat ggaaaatcaa cgtctgcggg aacacctgcg ggaattgaac
    16801 caagttgcac aagctccagc tgaaaatgtg aagcaggaac tttctaagtc tcgtatgaat
    16861 cttgaaaaaa tttatgaaga aggattccat gtctgctacg atttatatgg atcaagaagg
    16921 gacaatgacg agccttgtgc gttttgtcta gaagtgatct atcgcgaaag cggtcgatga
    16981 ccaataacaa gaggagactg gagcggagaa atactgctcc agtcttttta ttaaggagat
    17041 tgtgacagat gtataatcaa aaaagtttca agggaaatcc ggtatatggg gatttatatc
    17101 ttgtaccgac gccaattgga aatttagaag atatgagcta cagaagtgtt cgtatgctgc
    17161 aagaatccga tcttatcgca agtgaggata cgcgtaatac acaaaagtta ttgaatcatt
    17221 ttgaaatcca tacaccccaa aaaagtttac atgaacataa ttataaagaa cgtgtccctc
    17281 aattgattgc tttgttaaaa gaaggaaaaa cgattgctca agtcagtgac gcaggaatgc
    17341 cttccatcag cgatcctgga catgagctag ttttagcctg cataaaagaa gggatttctg
    17401 tgatctctat cccaggacct acagctggga tgacggcttt gattgcttca gggctagtgc
    17461 ctcaaccatt tttattttat ggcttccttc cacgtaagaa aaaagaacag aaagaaacat
    17521 tgaaaaagct aaaagaacag acagttacgc tgatttttta tgagtcacct tatcggatca
    17581 ctgctacatt gacgaatttc ttagaaattt ttggaaatcg ccaagtcgtt ttgtgtcggg
    17641 aattgacaaa ggtccatgaa gaatacctta gaggaagtac ggaagagcta ctcgcttata
    17701 tcgaagaaca tccagtaaag ggtgaatgtt gtctgcttgt agaagggaat ttgttcgaaa
    17761 tgccagtgac ggaagttgat gaagagttgg gaacgttaaa ggaacaagta gaagcaaaga
    17821 tcgcttcagg cgaaaaacca aatgctgcta tcaaagcagt agcgctgaaa aatgggctga
    17881 aaaaacaaga agtctaccgt cagtaccatg aattagactg agatagtata agttgtctat
    17941 aatgaaagac taatgaggaa atcagctact aacttttcaa atctcttgaa cgcgaacgaa
    18001 tgttcttgta taatgaataa gaggtgagga tgatggagct gcaatttcct ttacataatg
    18061 atacatcaag aaaaatcatt catattgata tggatgcttt tttcgcttcg gttgaagaac
    18121 gagatcatcc tgagtttcgc ggacatccat tagtaattgc cagacacccc agtgacactg
    18181 gtgggcgtgg agtagtgact acagcaaatt atgaagcaag aaaattcgga attcattcag
    18241 caatgagtgc acaaaaagcg tatgagcttt gtccgcaagc catctttaag cctggcgacc
    18301 atcataaata cagcgatatt tccaaacaag tacgggaagt attctatcgt tatacagata
    18361 ttgtggaacc agttagtatc gatgaagcgt atcttgatgt gaccgaaaat aaaatcaatt
    18421 gcaagtcagc catcaaaatc gcccgaatga tccaagcaga tatttgggag agtgtccagc
    18481 taacatgttc tgcgggagta agttacaata agtttttggc caaattagca tcagactatc
    18541 aaaaacctag aggaatcacg gtagttgccc ctcaagacgc tgtgccattt ttaaaagctt
    18601 tgccaattga aaaatttcat ggggtaggga agaaaactgt acctagaatg catgagctag
    18661 ggatttatac aggaaaagac ctatatgaat gcacagaaat gatgttgatt cgaaattttg
    18721 gaaaaatggg ctattctctt tatcgtaaag tcagaggaat ccatgattct ccagtaaacg
    18781 ttacaagaga gcgaaaatct gtgggaaaag agcatactta tgggcagccg ttgcaaacgg
    18841 aagaagcagt gctgactcag ttgcgccaac tagctgaaaa agtagaagaa gcactgagaa
    18901 gagtccaaaa acatgggaaa acagtagttt tgaaggtcag gtacacggac tattctactg
    18961 tgaccaaaag agtgacattg ccagaatata tctataaaaa agaagcactc ttttatcaag
    19021 caagccttat atgggaggaa atcttgggag tagaaaaagg aatccgattg ttagggatta
    19081 ctttgacgaa tctggacccg atgacttatg aaaacatcgt ccttccatta tgggaaaatc
    19141 aagaaatata aaaacagctt tgagagttga aaccggaaat ccgttttctc tcccaaagct
    19201 gtttttatat caagtcttgc tttttgattt gttcataggt ttctgttgca tccgtacatt
    19261 tttcccaaat cacaacttga ttggattcta aagatttttg gacgtcaatg atccgctggt
    19321 tgctacttcc gcgaaattgt agttttaggt cacgtttgct taattcaaag cgtccgtcaa
    19381 caaggatatc gatttgcgaa aggagttcta atttatcttc tgaatcttgt agcaattcat
    19441 caaaggtata gcctgtccat gaccagatat cttttgtcgt accgaactct tttcggatac
    19501 gtcgtacgac ttgcagacaa acatctgtat tcaaaaaagg ttcgccacca agtaaagtta
    19561 atccttgcac gtaatcgttg cgcaagtcag cgatgatttg ttcttctaat tcaggtgtga
    19621 atggtttgcc atatcggaaa ttttgtgcag ctttgttgaa gcagccttcg caggcaaata
    19681 agcagccact aacgtaaaga ctgttgcgga caccttcacc atcgacaaaa ttaaacggtt
    19741 tgtagtcagc aatatagttt tggctgtagt cttttgctaa ccattctttt ggttttggat
    19801 ttctcataaa aaaacttctt tcatttaagg ttcaaagata tagctattga agataaaatc
    19861 tactcgacca cataaataag aacaaactga cctaaatcca ttgttcaaga aagcttgttc
    19921 ttattttgat agagggcgtt caaagataca aagccatcga aagagggtgg tgaaaaaaga
    19981 cttgtcatag cctcttattc tgaataaacg gtgttcaaaa gcttgcatct gcagtaataa
    20041 gcccaactaa acgaaaaata tgaggaacta tttttgttta gctattctta ttacttgatg
    20101 caggacagct ttttcacaac ctcatttcat gtgtttcaca cgtgaggaaa tttctttatg
    20161 gcggccatgt accatcggac gagcttgcgg atttcctaaa tagccacaag tacgtttgac
    20221 tacatcacat gtttttggat catgatttcc acattctgga cattcgaacc ctcgttctgt
    20281 cggtttgaaa tcaccttcga aaccacattg atagcaatga tcgattggcg tattcgtacc
    20341 aagatacccg attttgtcat atgcaaaatc ccatacagct tctaaagctt tcggattttg
    20401 ttggagcata gggtattcac agtagtggat gaatccacct gaacaatatt ttggataatc
    20461 cttctcaaat tccaattttt caaatggcgt tgggttttta cgcacatcat agtggaaact
    20521 gtttgtataa tattctttat ctgtgatatt ttcgatgatg ccgaattttt ctgtatccaa
    20581 acggcagaaa cggtcagtta gactttcact tggagttgaa tagacactga aatgataacc
    20641 atattcatcc ccccatgcat ctgcattagc ttttaattct ttgacgatat caagtgtgaa
    20701 agcttttgct tctgggtttg tttcccattc gccaccgaag aaagctgaag caacttcata
    20761 caatccaatg tagcctaacg atacagtagc tcgacggttt ttgaataatt cattgacaga
    20821 atcggtacgt gaaagacgtt tcccgaaagc accatacata tataaaattg gcgcatttgc
    20881 tggaatggct tctttacaac gttctacacg atagagaagc gcatctttca tgatttctaa
    20941 gcggtcagac agtaactgcc agaatttatt ctgatctcct tttgattcga tcgcgattct
    21001 tggcaaattc aatgtaacaa cacctaaatt cattcgtccg acatttactt cttgaccatt
    21061 ttcgtctttc cacccttgca agaatgaacg acagcccata ggtactttga aacttccagt
    21121 taattcaacg attttatcgt aattcagaat atcaggatac attcttttcg ttgcacattc
    21181 caatgctagt tgtttgatgt cgtaattagg atcttcaggg tttaagttca cacctttttt
    21241 caaagtgaag atcagtttag ggaagatagc tgtccgcttt tcactcccta atccattgat
    21301 tcgaatctgt aaaattgctt tttgaatttc tctttcaaac cagttttctc ctagtccaaa
    21361 tcctaatgaa gtgaaaggag tttgtccatt tgaagtaaat aaggtattga tttcatattc
    21421 caaactttgc atagcatcga agatatcttt tttggttttt gcttttgcat attctttttg
    21481 gcgttctggc gaatcgatcc attcttccgc gtcttttaga tgttttttat agttcaattc
    21541 tgcaaaagga gcaagcaatt catctgttcg gtcggcagaa cagccaccat attgacttga
    21601 cgctacattg gcaataatct gtgagatttg tgctgtggcg gtctggatag attttggcga
    21661 ttcgacttcg gcattgccga ttttgaaccc attgttcagc atgcctttga aatcaatcaa
    21721 gcagcaattc gtcatcggtg tataaggatg ataatccaaa tcatggtaat ggatatcgcc
    21781 tttttgatgc gcatttgcta tatgtggtgg caacattttc agtccgattg attttccaac
    21841 gatcccggct gtcagatctc gctgtgtatt gaaaacatta ctgtctttat ttgcgttttc
    21901 gttcacgaca gtttggtcct tgttgattag cttttcaatc gaaaagttga tatctgttgc
    21961 tttactgcga gcaaaatctc gtttggtacg ataattgatg tactcttctg ctaattcata
    22021 ttcgtttttt tctagtaata tatgttccac gatgttttga atctcataga ttttgacatt
    22081 ttcagcaaac cggcttttga tttcttggac aaccaagtct gcaatcattt gaattttttc
    22141 ataagtaagt ggtgataatg agccgtgaat tttcttttct gctttgatca gtgcttcatt
    22201 gatcttttgt tcatcgaaat caacatggcg gccatcgcgt ttgatgactt tcatctggga
    22261 tgtctctggc tgctgagtaa cgacagtttt ttcttcataa tttactttca ttatcttcaa
    22321 ctcctgctaa attgttcttg tctatcataa aacaaaatcg gggaaggagc aactaaatat
    22381 cggctatata tagtattcaa tgtgctgtat aatt
//
LOCUS       DADVXB010000037        22324 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.037, whole genome shotgun sequence.
ACCESSION   DADVXB010000037 DADVXB010000000
VERSION     DADVXB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.037"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(109..489)
                     /gene="yajC"
                     /locus_tag="KB902_001084"
     CDS             complement(109..489)
                     /gene="yajC"
                     /locus_tag="KB902_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBB6807925.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKKEK"
     gene            complement(586..1731)
                     /gene="tgt"
                     /locus_tag="KB902_001085"
     CDS             complement(586..1731)
                     /gene="tgt"
                     /locus_tag="KB902_001085"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBB6807926.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1949..2647
                     /locus_tag="KB902_001086"
     CDS             1949..2647
                     /locus_tag="KB902_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6807927.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSDATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFEGLFIGGVIGLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2815..5454)
                     /locus_tag="KB902_001087"
     CDS             complement(2815..5454)
                     /locus_tag="KB902_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6807928.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(6073..7104)
                     /gene="queA"
                     /locus_tag="KB902_001088"
     CDS             complement(6073..7104)
                     /gene="queA"
                     /locus_tag="KB902_001088"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBB6807929.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            7297..8472
                     /locus_tag="KB902_001089"
     CDS             7297..8472
                     /locus_tag="KB902_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6807930.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            8476..9117
                     /locus_tag="KB902_001090"
     CDS             8476..9117
                     /locus_tag="KB902_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807931.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPFGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            9114..10031
                     /locus_tag="KB902_001091"
     CDS             9114..10031
                     /locus_tag="KB902_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6807932.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYDQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            10028..10699
                     /locus_tag="KB902_001092"
     CDS             10028..10699
                     /locus_tag="KB902_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807933.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATDGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(11241..11729)
                     /locus_tag="KB902_001093"
     CDS             complement(11241..11729)
                     /locus_tag="KB902_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBB6807934.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(11930..12196)
                     /locus_tag="KB902_001094"
     CDS             complement(11930..12196)
                     /locus_tag="KB902_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6807935.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQSNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(12196..12459)
                     /locus_tag="KB902_001095"
     CDS             complement(12196..12459)
                     /locus_tag="KB902_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6807936.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSGFTNIDDIDWEAL"
     gene            complement(13090..14280)
                     /locus_tag="KB902_001096"
     CDS             complement(13090..14280)
                     /locus_tag="KB902_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinan endo-1,5-alpha-L-arabinosidase"
                     /protein_id="HBB6807937.1"
                     /translation="MTAINGVHDPTIIEHEGTFYLYSTDTQQPKTAGVPIRSSKDLIH
                     WQFEKQALSEMPEPAVKWSKAQGLWAPEVIRYKDEFRMYYSASTFGSTTSFIGLATAS
                     DPLGPWEDQGEVVKTNATLAQHNAIDANIAFDRSGEQWFVYGSFFGGIYIAPLNKETG
                     KLQEKSYGQRIAFRPKTVDTAIEGPFIYYHPETDYYYLFVSFDSLNDSYNIRVARAKE
                     ITGPYLDWHGTAMTDQEKTPTEVGTKLLGSYQFSEETVVYAPGHNSIFTQSNKESFVV
                     HHARRKPFSDQFHLQIRKLYWLESGWPVISASIYQGSVSRMPEQETLLGKWEIIQFDY
                     ESQIISSQQHEITELKKEGRSYLWEGNEFVPYYEYIDQKERLFFSGINDQGVAFLGRK
                     VCEE"
     gene            complement(14333..14599)
                     /locus_tag="KB902_001097"
     CDS             complement(14333..14599)
                     /locus_tag="KB902_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807938.1"
                     /translation="MTCKGCEVKDVAVAAQEDIESLIAEQLSLERDLALPEIVSRRIA
                     VCETCPLRLNHTCTKCGCFYRFRANLAKKNCPAGMWEQTGQLVK"
     gene            complement(14604..16049)
                     /locus_tag="KB902_001098"
     CDS             complement(14604..16049)
                     /locus_tag="KB902_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6807939.1"
                     /translation="MTIKILHTKSGTTISKYIYGHFAEHLGRCIYEGLYVGEDSPIPN
                     KNGMRIDVVEALKNIQIPVLRWPGGCFADEYHWKDGIGPKENRKTMVNTHWGGVTENN
                     HFGTHEFFELIKQLQCDAYVNGNVGSGTVQEMSEWVEYITMDGISPMADLRRENGHEE
                     AWEMKFFGVGNENWGCGGNMRPEYYADLYRRYQTYVRQYGDKKIYKVAGGANVADYHW
                     TETLMKNAHWLMDGLSLHYYVHPQGWEEKGSALEFNEAEWQVTCEKAAYMDELLTRHS
                     AIMDQYDPEKRVGIIVDEWGTWFSAEPGTNPGFLYQQNTIRDAMVAAITLNIFHKHAK
                     RVHMANIAQTVNVLQAMILTDGEQMVKTPSYHVFDLYKVHQDAETIDSHGTSSDTITY
                     TISKKEDTIHLSVCNFATQGTEELSFSLETAINKVKEARYIVGDKMNAHNDFDHPEDV
                     AIQDFTAYDVEENKVSLRVPAMSVLTISLTV"
     gene            complement(16060..17682)
                     /locus_tag="KB902_001099"
     CDS             complement(16060..17682)
                     /locus_tag="KB902_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6807940.1"
                     /translation="MTTKINMISRMIPVFLTSFFLMGCQTGEAAEQLIQKEWETTSKE
                     RVSIHDPSITTIHEENQELFYVFGSHLAQAKTSDLRTWEVPFSHEYESMEDNIIYGNT
                     KENLAETFKWAGYDDVDSKGGYSLWAPDVIWNADYEWSNGDKGAYMLYYSASSTWRRS
                     AIGLAVAKTIEGPYSYSDTVIYSGFTEKDSTDGSDRNTNYQNTHLAKLIKDGKISGFS
                     ENWSIEAGLTYNTDYAPNAIDPALFYDEEGKLWMTYGSWSGGIFLLEVDPATGKPMYP
                     GEDSTTEDGRIIDRYFGIKLSGGYHQSGEGPYIVYDEKTDYYYLFVTYGGLAAKGGYN
                     MRLFRAEKPEGPYLDAQGNSPILDKGEQNVNYGIKLIGNYQFSFQQMGYRAAGHNSAI
                     IDENGQWSLVYHTRFNNGTEAHEVRVNRMYMNEEGWPVPAPYEYRGNEQVADALTEDE
                     IIGRYEIINHGTDNGTTMLKTQMIEFQKDGNVTGDLTGTWTYDAGYLVLTFEETTFKG
                     ILLTQEITEFEQQKLTFSTIGDNNESIWGIKE"
     gene            complement(17701..18657)
                     /locus_tag="KB902_001100"
     CDS             complement(17701..18657)
                     /locus_tag="KB902_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6807941.1"
                     /translation="MAENYLEPIVLERADPWIYKHTDGYYYFTGSKPGYQEIELRRAK
                     TLKGLTDGEVKVIWTAHAEGSMSELIWAPEIHFIQGKWYIYFAAADHGEVRNDQHHHR
                     MFAIENAKENPFEGEWVEKGQIKTQFESFSLDATVFEHRNRLYYVWAQVDPNIPGNSN
                     LYLSEMENPWTLKGKQILLSIPYYEWEKIGFKVNEAPAALIRNGKVFITYSASATDEN
                     YAMGLLWADEESDLLNGYSWNKLKEPVFSSSERNSLYGPGHNSFTIDEEGKQDILVYH
                     ARPEKNDYSDPLENPNRHAYVQPFTWHKNGLPNFGEPGVIKA"
     gene            complement(18673..19089)
                     /locus_tag="KB902_001101"
     CDS             complement(18673..19089)
                     /locus_tag="KB902_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807942.1"
                     /translation="MNRKLERNLLRASAVWDVCIGLVTMFGYYPWFEEQGIAAFQNQN
                     QYEYLQSSLIGMISKVVLIVALATILMGVISWINAKNMRDKQINKGTIRWMIACVIIH
                     LIIYDVIGVVLYLLATTMYMSKNKAIKILKTENGIF"
     gene            complement(19098..19949)
                     /locus_tag="KB902_001102"
     CDS             complement(19098..19949)
                     /locus_tag="KB902_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6807943.1"
                     /translation="MNTQKKHIPSMIIAYLFLIVLCIIWVIPLIFSFATSFRSQTEIV
                     STGFRLLPVNWILDNYIAILTNTSTAPIMQWLWNSLFIAVTHTVLVVIVVSVTAYGYG
                     RTRFKYRDRIFYLLMGISMFPGVVNLIPSYKIIETFGWVNSSLAMIVPGLAGMGNIFL
                     VRQFMKGIPLEFDESARMDGADEFTIFSEIIVPLIKPVLIVAGLFSFTGSWNDFLWPV
                     IVYTDVSKMPITAGLLLLQDIYGNYRMIGQLMGSALIAIIPTVLLFLFAQKYFIESMN
                     LNAGIKG"
     gene            complement(19961..20851)
                     /locus_tag="KB902_001103"
     CDS             complement(19961..20851)
                     /locus_tag="KB902_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6807944.1"
                     /translation="MKGMKKKSINWASIAFIGPHMVLFIIFVCIPTVYGIYASFTQWN
                     LISDPVWVGLNNYKTLLFDSSSTFYTQFWNGLKNTFIFVLIMVPLQIIIPLMIAAALQ
                     HKKVKLKGLFQAVLYIPGLISVSAGSLIWSLIFHSRLGAVNNIFGFDFSWASRQPYAW
                     ILIFAVSIWGAIGGNMIIYRSALAGVNEDLYEAAEIDGAGSFQKFLNVTLPSIRFPLL
                     YTIVMTTAGAFNVFAQPLMMTGGGPNQSTTVLMMYIRSLAFSQGESIAGMASAMAVIL
                     GLIIMCVSVFQYFLLDRSNT"
     gene            complement(20896..22146)
                     /locus_tag="KB902_001104"
     CDS             complement(20896..22146)
                     /locus_tag="KB902_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6807945.1"
                     /translation="MKKKLIIIGALVAVVAIAFAGFKRYQSSEKEKYTINFWSPLTGD
                     DGAYMDKIVDEFNEQSGSDYKINHVITSDMYTKLSTVVSSKNGIPDLTLMHSYKVEEF
                     VNSNILDTVEPLVSHQPELQKGNYLDTAWNAGTIGGTQYTIPLDIHASAMYYNQDLLE
                     KYDVTSWLDDNIVTFDEMMSLAGKMDEGDYVVNNALLSWVILAQIRNLGGAISDEAGN
                     PTVNTPEMKEALERIKALTDAGLMTPYGEDGYLMFQGGNVLLSTDGTWTSTAHDAVEG
                     LNWGVTNIYSTSDDIATNRAASHMFGMLKSESRTDEKEEVIAQFLEFVRTNSIEWAKA
                     GQIVASKDILESDDYQQYPQSFFTSTSEEEDTLYIFDYVYFSYVLEALDVYCTDIAYS
                     ELDLDEGLATMQQYVEDKIAEVAK"
BASE COUNT         6344 a         4887 c         4094 g         6999 t
ORIGIN      
        1 attcaatatt gagcaatata tcctatactc ttatctcttt cttttttgaa taaaaaatga
       61 ggtaggacat ctttctgccc tacctcgtct ttaaataagc tttgatactt atttttcttt
      121 cttctcttct gtctcttcca gcgtttctgt tgtttcagtt tttacttcaa ctgtctcagc
      181 tggttcttct gttgtttcaa cagtagtcgt tgcatcattt gttacgacag tccctggttt
      241 gaccgttttg attgctgcac gatcgtactc aaggaagatc ccttcgcagt ctaaaacaac
      301 tgtccgtttg tcattgtcga tttctgaaac aactccatgt aatccgccga tcgttacgac
      361 tgaatcacct ggtttcatgc tatctaacaa gttttgacgt tcttgctgtt gtttcttttg
      421 cgaacgtgac ataaaaaacc acattgctaa tagcgcgata aacatcacaa gcattggtaa
      481 tgttcccatt tttttcacct cactaattct gtatctacaa aaaacacttt agcagaaaaa
      541 tgctgctaac actagttttt tacttaattt ttaaaagatt ttcctttaga agctttttgc
      601 gttttcttta ttgaacccgt attcttcaaa aaaggcttct ctaaattcaa gcaaattatc
      661 atccatgatt gcttgacgta cttgtttcat tagattcaac aagaagtata aattgtggta
      721 agaagtcaaa cgaatcccaa atgtttcatc acatttgatc aaatggcgga tataggcacg
      781 tgtatagttt ttacatgtat aacaatcaca tttctcatca attggacgga aatcatgagc
      841 atacttcgca tttttcacta ctagacgacc ttgagaagtc atacatgtgc catttcgagc
      901 gattcgagta ggcaagacac agtcaaacat gtctactcca cggataacac catcgatcaa
      961 tgaatcagca gcaccgacac ccatcaagta acgtggtttg ttttcgggga tcaacggtgt
     1021 agtgaattct aatacacgat tcatttctga tttaggctcc ccgacagata acccgccgat
     1081 tgagtaacca gggaaatcca tcccgactag atctttcgcg ctttgacgac gaagatcttc
     1141 aaatcctgct ccttggatga ttccaaataa tccttgacgg tctgggttag catgagcttt
     1201 caatcctcgt tctgcccatc gagacgtacg ttctactgat tttttcacgt aatcgtaact
     1261 ttcatcgaat ggtggacatt cgtcaaaact catcatgata tcagagccca atttattttg
     1321 gatgttgatt gctttttctg gtgataaaaa catacgcgaa ccgttcaagt gatttttgaa
     1381 atgcacgcct tcttcttcga tattccgcat atcacttaat gaaaaaactt gaaagccgcc
     1441 tgaatctgtt aaaatcggtt gatcccagtt cataaattta tgcagtccgc cagcttcttc
     1501 tactaagtct tcaccagggc gtagccataa atgatatgta ttacttaaaa taacgccagc
     1561 acccatttct ttcaactctt ctggggacat tgtttttact gtagctaatg ttcctactgg
     1621 catgaacatt ggtgtgggga aagttccgtg tggcgtgatc aattccccta aacgcgcgcc
     1681 agtatgtttt tctttcttga ttaaacgata gcgaatggca ggttgcgtca ttcatttccc
     1741 tactttctat ataaaatatc ttgacaactc ccaccatcat aatcgtttca agtgcttttt
     1801 gcaagttccc tcggcttcct tctactttat ttaatattct tttttttatc ctttttttat
     1861 gaataacaaa aaaaagaaaa acattatgac agaaatattt tttgatacat ggtatattgg
     1921 tgttattaaa gaaaaggagg gaaaaatcat gcaatcttct gcagaattaa aacgccaagc
     1981 aaaagagagt ctaaaaggac gttggggaca agctgtttta ctaaatctaa tccctacatt
     2041 gattggtatt gctactattc ttcttattat gattcctatt atcttgtttg ccaccaccat
     2101 atatgatgga tcagcgagcg tctcagatgc gacaacttca ggaggcggta gttcaggagg
     2161 cggtggcgga attatttcca gcatcattag cgctttgttc atgagcggta tttcttggac
     2221 ttatcttgat attttacgtg gacaaaaaga tcagatcgaa ccattcaaag atgcatttcg
     2281 tggattcgaa ggtttgttta tcggcggagt gatcggctta gctgtgctga tctcgatctt
     2341 tacaacatta tggggtttgc tattagttat tcctggaatc attaaaagct attcttattc
     2401 tcaaagctat tttatctact acgatatcgt ccaagaaaca ggacaaacac ctaaagtact
     2461 ggatacgatc actgcaagtc gaaaattgat ggatggttat aaaggacaac ttttctggtt
     2521 agatctttca tttatcggct ggcatatctt agcattagca actgctggta ttggttatct
     2581 atggctcagc ccatacattt ccgcaacaaa agcagcattt tatgaacaat tgccaaaaga
     2641 tatttaaaag agagtgtgac ttgtgaccga ggggttggta ggagaacacc gtttatcgag
     2701 aggcagtaaa agaaacattc agcccattag caaaaaggag gtgtgacaac attcatgtca
     2761 cacctccttt ttgtatagtt ccagtaaaaa gaaaatcaac ttagaaacag ttaatcattc
     2821 ctcttcttct gcttccggta atcgatggaa cttgatcagt tcattcaccg cgattggtac
     2881 gatagataaa atccctacca agaaccagtg attcaaactg atgtgtacta ggccgaatag
     2941 ttcttgcgta aatggcagca aagcaacagc cgttgtaata gctaatgcca gtaacgccat
     3001 ttctaccaaa gctttattgg ttgctaaatt gactttgaag atcgattggc tgctgcgtac
     3061 attgaacaca tgcaaaatcg atgaataagc taagatcaag aatgcaacag tttgaccgac
     3121 atgctgactt gcatctaccc atgggctaat agtatcgaca taactaccta aatagtaacc
     3181 aaacagcgtt acgatggtga agactcctgc gtttatggcg attttttgca acaagcctcg
     3241 agcaaagatc ccttcgtttt tcggaatagg aggctgatcc atgatgccgt gttctgctgg
     3301 ttctcttcct aaagcaaatc ctggaagtcc atcagcaact acattgacaa acagtagttg
     3361 cacagctgta aatggtgctc cccatcctaa cagcatcgca atcaaaacaa taaagatctc
     3421 cgaaatatta cagcttagta aaaagttgat tgctttacga atattctgat aaactgaacg
     3481 cccttgacta acagcatcta cgatcgtcgc aaagttgtca tccgtcagaa tcatatctgc
     3541 ggcactttgc gccacatctg tccctgtgat ccccatggca cacccaacgt tacttgcttt
     3601 caacgctggt gcatcattca caccatcccc agtcatcgct acgactgctc ccgtacgttg
     3661 ccaagatttg acgatccgga tcttgtcttc tggcgttacc cgagcataga cagagagagc
     3721 tttgacacgc gcatctaatt cttcgtctga taattgatgc agttctgatc ctgaaagtgc
     3781 ttctgacgga tcattcaaga tacctaattc tttcgctatg gcactggcag ttaccacatg
     3841 atctccagtg atcatgactg ttttgatacc ggcttttttc gctcgcttga ttgctccttt
     3901 actttctgga cgtggtggat cgatcattcc gatcaggcca atcaaacgta agtctttttc
     3961 caatgcttca gaagaaatat cttgcggttc ttcgtcataa gtagcataac caacagcaat
     4021 cactctcagt gcccgtttac caaagcgatc attaacgatt gctgcttgtt ctacatcgcc
     4081 tgaactaaag cgcggagcca gaacatcgaa tgctcctttg gtgattgaga tgtatttttc
     4141 gcccatttga tgaaccgttg tcatcatttt tcgttcggaa tcaaaaggaa gctcgtttac
     4201 tcgtggatat ttttcttcta attctgcttt tgtatgataa ttctcttcaa cagccctaac
     4261 gatggctacc tctgttggat tacctttgat aacaaggtcg tcatcttctt gctcgaccgt
     4321 cacatctgta catagtgcag ccattttcaa tatttccatc gcgctgttcg tcattgaatc
     4381 ttcgatattc gttacttcat cttctttgct ccatacccgg cggacgcgca tttcattttg
     4441 tgtcagcgtt cctgttttgt ctgagcagat aacattagca gttcctagcg tttcaactgc
     4501 tggcaactgt cggatgatcg catgtttcct cgccatcttc tgcacaccgt atgcaagtgt
     4561 caacgtaaca ataacagtca aggtttccgg tacagctgca acagctaagg aaatcgaagt
     4621 catgaacatc tcaaggagtg gttctccttg cagttcacca atcacaaata ctaaagccgc
     4681 agccgctaaa gcgatcatac tgattcgttt gcctagctga ttcaatcgga cctgtaaagg
     4741 tgttttttgc atagtatttt cgttcaaaag atccgcgatc ttacccattt ctgtagccat
     4801 accaatggca gtgacgatcg ctttcccacg acctgcagca accgtacatc ctttaaatac
     4861 catattaagt tggtcaccta atgactcatc ttcttcagca ataaatgctg catctttttc
     4921 aactgcttca ctttctccag tcaacgccga ttcttctaca cgtaattgtg atgcttcgat
     4981 caaacgggca tcggcagaaa tagcatcacc ggactctaaa acaagaatat cacccactac
     5041 cagttgctct gactcaacag tggtcacttt gccgtctcgt atgacagttg ccgtttgttt
     5101 attcatatct tgcaaggatt ccagtgcttt ttctgcgttt ccttcttgga caatcgccaa
     5161 taccgagttg atcacaacga tagcgatgat cagcagtcct tcaaataaat ccccatgttc
     5221 tgtagcaaat gcggtataaa aggaaatcac cgctgctaca agaaggatga tcgttgtaaa
     5281 atccgacaag cttcgaaaga attttttgat catcgattct ttcggcgcct catcgaattt
     5341 attcaatccc tgcttttttc gccgttcatc cacttcttgt gaagacaacc cagtatctgg
     5401 atctgcttct gttaccttct ttacttcttc tattgtctgc ttgtattctt ccatcctatt
     5461 cctcctttaa aatcttcgta caaaaaaagg tacttatttt actataacat cattttttta
     5521 tttacttcaa ataaagggct tatcgattat ttgttaagaa agcgtaaaat ttaaagtgct
     5581 tatatttgca aacgctacca aaggatgcta ttatatagat gtaaggaagg aggataccat
     5641 caaatagaca gaagaatttc tcgatagaac agtgtaagca aacaaagttg ttagaagtac
     5701 aggtttcacc cagacatgcg tgtagagtac aaacctataa atagtgaatg cgtatggatg
     5761 tttggatcac gaagtatccg aaacaagaag taatgcgata cgtaacaatt gaataacgta
     5821 aacgtctgaa aattgaatag gaacaagaga tgtttcaaat gttgaagatg taacgaaaac
     5881 aaaatttttg tttaacatga agaaattcaa caccgtgctt tgcatgtatg atggaaagtt
     5941 acaatcattt ctgtttattt gaatccttcc gaggtacaag aaagccgagc ttatcgagag
     6001 ctcggctttt tctttgtcat aaaatctttg taaagctttt ttgttattca aaactagcgg
     6061 tttttcataa ccttatttca cgaacatcgc atctccaaaa ctaaagaaac gatagcgctc
     6121 ttcaatcgca tgctggtaag cagataaagt caattctctt cctgcaaagg cactaactaa
     6181 catgactaaa gtcgattttg gcaaatggaa attagttgag aaagcttcta ccactttgaa
     6241 ttcatagcca ggcgtaatga aaatatcagt ccatccgctg tctgctttga tttctccatt
     6301 aaatttcgtt ccaatcgttt ctaatgttcg aattgaagtt gttccgacag ccacgatttt
     6361 cccgccattt ttacgtactt ggttcaatcg ctcagctgct tcttccgtca aacggtagaa
     6421 ttcactatgc atatggtgtt cttcaatttt atctacgctg acaggtcgga atgtacctaa
     6481 ccctacatgt agtgtcagat agactaattc aacacccttt gcttcgatct catcaagtaa
     6541 ttctttcgta aaatgcaatc cagctgttgg cgctgcagca gaaccatttt ctttcgcata
     6601 gacagtttga tagcgatctg ggtcttccag acgttctttg atatatggag gcaatggcat
     6661 ttctcccaat gattcaagaa tctctagaaa aattccttca tactcaaagt caatgatccg
     6721 tccgccgtgt tccaattctt ctttcactac tgcttgcaat ctgccatcac caaaagagat
     6781 tcttgtccca actttggcac gtttcgcagg tttgatcaat gtctcccacg tatctccttg
     6841 tgtattcgtt agaagaagga cttctaaatg cgcaccagta tctggttttt ctccatataa
     6901 acgagcaggc agaactcgtg tattattcat aactagcgca tcaccaggct gtaactcttc
     6961 aatgatttca tggaaatgtt tatcttccat ctctccagtt ttccgatcca aaacaagtaa
     7021 acgagaatga tcgcggtctt ttaatggtgt ttgtgcgatt aattcttccg gcaagtcaaa
     7081 atcaaaatct tctgttgtta acatatcgtc actcactttc tatcatgtgc ttcatcattc
     7141 tatcatgttt ttcgttctgt tggcaaaatc agcacttttt cacttctatt ttttgttttc
     7201 ctaaataaaa aaactaccct atttgtattt tttcattgtt ttaggcatac tagtaataga
     7261 tagttcttca ttgaaaatag aaaaagaggt ggcaccatga ttgaatttca aaatgtgtca
     7321 aaaatttata aaggtggaaa agtcgctgta gaggacgtca atctttcatt tgaaaagggt
     7381 gagttcattt gttttatcgg tacgagcgga agcggaaaaa cgacgacgat gcggatgatc
     7441 aaccgaatga ctgatccaac acaagggaaa attttgattg atggaaaatc catccaagaa
     7501 attgatccag tggaattgcg acgtcagatc ggctatgtta tccaaagtat tggattgatg
     7561 cctcacatga cgatccgtga aaatatcact cttgtccaaa aattgttgaa agtcagtcaa
     7621 gaagaacgga ataaaacagc tgaaaaaatg attgatcttg tggaattgcc ccgtgagatg
     7681 ttagatcgct acccacatga attatctggt gggcagcagc agcgtattgg agtcgttcgt
     7741 gcccttgcag cgaatcaaga tatcatcttg atggacgagc cattcggtgc gcttgatccc
     7801 atcactcgtg attccttgca agaccttgtc aaagatttac aagagcgttt gggaaaaacg
     7861 atcgtatttg taacccatga catggatgaa gcgattaaac tagcaagccg tatcgccatc
     7921 atgagtgaag gccgtgtgat ccaatttgat acaccagaaa atattttacg tcatcctgca
     7981 aacgatttcg tagaagagtt gattggagaa gatcgcctac tacaagccaa gccaaatgcg
     8041 acaagagtcg gagaagttat gctaaataca gcaatcacga ttacaccgga aaaatcatta
     8101 caagaagcaa tcaaacttat gagggaaaaa cgtgtagata cgttgttagt taccgataat
     8161 tcgaatgtat taaaaggatt tatcgatgta gaaacgttga ataaaaagcg aggaaaagta
     8221 tccagtgtcg gcgacatatt aaataaacat gttttttacg taaaagaatc cgcctatctt
     8281 cgtgatacct tgcaacgcat tttaaaacgc ggactgaaat acgtgccggt cgttgatgaa
     8341 cagaacaaag ttgtaggtat cctgactcgt gcatcattag tggatatcgt ctacgatgtg
     8401 atttggggag aagatcccgc aactactgat gttgcagagt cagctactcc tgaagaatct
     8461 aaggaggtct gacctatgca gcagtttttt catcaacacg gttcagaaat tctctcaaaa
     8521 ggttttgaac atctttatat ttcgggactt gctttgatca ttggtatcat cattgctgta
     8581 ccgtttggtg tcttactgac acgttttcca aaagctgcca cgattgtgat tggcttaacc
     8641 agtgccttgc agacaatccc ttctcttgct ttattggcat tgatgatccc gctatttggc
     8701 gtaggtaaat tacctgcgat tatcgcactc tttatttatt cattattgcc gattttacgt
     8761 aatacgtaca ttgggatgaa aaatgtcgat tggaattatc gggatgtggc aaaaggcatg
     8821 gggatgactg agttccaatc cattttttcc gttgaattgc ccattgctat gccaacgatc
     8881 atggctggta ttcgtttagc tgccgtttac gtgattgcat gggctacact tgcttcttat
     8941 atcggggctg gtggtttagg tgatttgatt tttagtggac tgaataatta ccaaccagat
     9001 ctcattttgg caggtacgat ccctgtaacg attttagcac tattggctga ttggcttcta
     9061 ggtctcttgg aacaccggct gacaccgatc gcacttagag aggagaatga agaatgaaac
     9121 gtatactaaa aatgaccatg gttcttttct ctcttcttat acttgcgagt tgttctttcc
     9181 ctggtcttgc cagcaataca gatgaagaca ccatttcgat cacaggtgga atcacttcag
     9241 aagcacagat cttagcaagc ctagttgccg gaatggttga acattataca gataaaaata
     9301 ccgcaatcat caacaatctg gctaccacaa ctatcaacca tcaagcgatg atgaacggag
     9361 atgcttcaat ttcagcggct cgctacacag gaacagattt aacgactaca ttgaaccttc
     9421 ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa agatgaattt gagaaaagat
     9481 acgatcaaac gtggttcccg tcctatggtt ttgaaaatac gtatgtcttt cttgttcgaa
     9541 aagacaccgc acaaaaatac catttatcta aagtcagcga tctgaaaaat gtagcggatg
     9601 aattagtagc tggtgtagat acttcttgga tcaatcgtaa aggagacggt tatgacggct
     9661 tccaagaaac ttatggcttc tccttcaatt cgatattacc tatgcagatt ggacttgttt
     9721 atgacgcagt cgaagcagga aaaatggata ttgttcttgg ctactctacg gatggacgga
     9781 tcgccagtta tgatctagtc atgttggaag atgatcgtca attcttccca ccatatgatg
     9841 ctgctccagt tgtagacaac aagatattag ctgatacgcc tcatttaaaa gaagccttaa
     9901 ataagttagg tcataccatc agtacggaaa aaatgcagga attgaactac gaagcagata
     9961 ataatctagt ggaaccatca gtagtagcac aacgtttctt acaagaaaac cactattttg
    10021 aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa caatttttct attatttcca
    10081 ggaaaatggc tcctatatct ttgcacaatt tatccgtcac ttcctgattt ctatctatgg
    10141 tgtcctcttt gcagcagttg tcgggattcc ggttgggatc atgatttcta ggagacgtaa
    10201 attagcaaac tgggtgattc gtttggcgaa tatcatccag acgatccctt ctctagccat
    10261 gatctccatt ttaatcattg gattaggcct gggagtcaat gtcgtgattg ttactgtatt
    10321 tttgtattcc ctcttaccga tcatcaagaa tacgtatacc gggatgatcc aagtagataa
    10381 aaacatcctt gatgtcggca aaggcatggg gatgactgct agacaacgac tattcatggt
    10441 agagttacca ctctctgttt ctgttatcat ggcaggcata agaaacgcgt tagttgttgc
    10501 catcgggata accgcgatcg gtgcattcgt cggtgctggt ggtcttggag atatcattat
    10561 ccgaggaacc aatgcaacag atggcacatc gattatttta gcaggtgcat tgccaactgc
    10621 attaatggcg attatcacgg actggctttt aggtattttg gaaagacggc tagatccagc
    10681 cagccgtaca tcacgctgat gttattgtaa aaaacaaaag cttctgcgac catttgttgg
    10741 tcgcaaaggc ttttttagtt ctgtcatttt ttaaggcaat aatccactct gattcttccc
    10801 tccttatggg caaagagttg cttttcttag ctatttatcc attccgtata ctccaacttc
    10861 atactgccaa cgggttcatc tctgcatcca ccgactaagt ttttttctta tccgctaagg
    10921 cattttgcca atccattttc ccatcactcg tcatggaatt cataccacat gatctctaaa
    10981 tactcgtctg cttgttcttt gaattgggca tcaattctta catcctttgg cgtggctttc
    11041 atttaagcct tttccatcag tcctcgattg ttcgatgcct tcagctgaat catcaaaact
    11101 ggtgactgcc gtatcggtaa cttcgatcat cttttataca atcgggaact tgccatcctc
    11161 atccttggct aaaaacatat ctagccattc cagcttctcg ccatgggagg tttgcggttc
    11221 ctaaaaccgg tacacgattc ttatggactg catccgtcgc aactagactt ggcgatacga
    11281 tgatccttca ccagaagagc acccccgtaa accaattgat cgatatattg ccaataagaa
    11341 aagacattgg cgtaaaagat atcgatccct cgtgatgcat tgccgttgat actgctattc
    11401 atggccgaaa gcgccacgac tttgacttct tccgtttgag tgacattcat gttcggcaat
    11461 gtcgctttgg atacccgctc tgctaaagga acgacactgg tattgtattt cgtatctgta
    11521 tcttttccaa aagaccatgc caacgaatcc tctgggaacc aataagacga ctccggttga
    11581 ttgtccattg cttttttcaa catacttttg gctgtttctc gataaacgac atttccaatt
    11641 gtcttcgcct cactttggcg ataatcgatg gtcgttgcca ctgccaacac taacaacgat
    11701 gctccaattt tactgatttt ccttgtcaca cttcttcctc cttgttttac ataaacccgt
    11761 caacattcca ttcctaaact caaacaatga cccttcaaag gtggagatat aggaacaaat
    11821 taaagaaatc atgcaataaa tccaagaagg ttggttttag aacaaaaaaa gagtctcctt
    11881 tttggggaga ctctttgtta actatctaaa aaggttggct cttctcactt cactcataat
    11941 gtgtccaggc agaataaatt tccacaactt tattttcctc atcaactttg taaaccactc
    12001 gatgctgtct attcagcctg cgtgagtatc tgccttcatg tgtaggtctc agcttttcaa
    12061 aagactgcgt gggcatatat ggatcttcct tcaatgtctg aatcacttct tcaaattgtt
    12121 tctttaaatt cgattgcttg atttttctta aatccacttt cgcagagttt ttgattgcga
    12181 ctgtatagtt actcatcaaa gagcttccca atcaatatca tcgatattcg taaagccact
    12241 gtcatctttt tcgcggtctc gtactttatc taaagtacct gtttgctcaa gaaaaagggt
    12301 ttcttgaatc gctctccagt cttccagccc aatcaataca gcattgtttc cactacgatc
    12361 actaataatc tcgatttcag tatgattttc atttacctct ttcaataact gataaaaatt
    12421 tttacgagca gtgctaggat tcatcgttgt attagccatt gtctctcctc ctttttctga
    12481 tataattata gcgtacttga ttaagtacgt caaaaaatac aataaagcac ttaaattcag
    12541 caaacttttc ctctttttta catagagaaa aagacccctt tttagggagg atctttgtcc
    12601 acgctcactt cttactcctt tacgactagc ggtagccaaa cgtaaagtaa ttggtaacaa
    12661 cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag tctatgcaac aacaccaata
    12721 cacgaaggtt cctcgttgca gtgtgacttg attgatatct tgaataacct gaggatacgc
    12781 acgaaagatt tgtaacggtt attcaaaact gattttggcc gtcaagtctt ctactgcctc
    12841 aaaaatgatt gcctctttcg tctcctgtca ttcatgttca ctatcgattt gatacttgct
    12901 tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac tgagttatgg taacaaaaaa
    12961 tggtcacttg acgaggctga gattcctact tatggcgcca gattattaaa aggcagtatt
    13021 tagtaaaaag ggcagcagta tacgtttata agcagcacaa tgcaatctgc tcattgtgct
    13081 gcttgttttt tattcttcgc acacttttcg accaagaaac gcaacgccct gatcattgat
    13141 tccagagaaa aacaaccttt ctttttggtc gatgtactca taatatggga caaattcatt
    13201 tccttcccac aagtaacttc gtccttcttt ttttaattct gttatttcat gctgttgaga
    13261 agatataatt tgagattcgt aatcaaattg gatgatttcc cactttccta acagagtttc
    13321 ttgctctggc attcgtgaaa cacttccctg atagattgaa gcagagatta ctggccagcc
    13381 tgattccagc caatagagtt tacgtatttg taaatggaat tggtcactaa atggttttct
    13441 ccgtgcatga tgcacaacaa agctttcctt attggattgc gtaaagatcg aattatgacc
    13501 aggagcgtat acaactgttt cttctgagaa ctgataactg cccaacagtt tggtccctac
    13561 ttcggttggc gtcttttctt gatccgtcat ggccgtacca tgccagtcca gatatggccc
    13621 tgtaatttct tttgctcggg cgacacggat attatacgaa tcgttaaggg aatcgaaaga
    13681 aacaaacaaa taataataat cggtttcagg atgataataa ataaatgggc cttcaatagc
    13741 agtatcaact gttttcggac gaaaagcaat ccgttggcca tagctctttt cttgaagttt
    13801 tccagtttct ttgttcaatg gagcaatata gattccgcca aagaaagaac catagacaaa
    13861 ccactgctca cccgagcggt caaaagcaat attggcatcg atcgcgttat gctgtgcaag
    13921 agttgcattg gttttaacaa cctctccttg atcttcccaa gggcccaaag gatctgatgc
    13981 tgtagctaag ccgataaaag aagtggtact gccgaatgtc gaagcagaat aatacatacg
    14041 gaattcgtcc ttgtagcgaa taacttccgg tgcccatagt ccttgagctt tgctccattt
    14101 tactgctggt tcaggcattt ctgacaatgc ctgtttctca aattgccaat ggatcaaatc
    14161 ttttgagcta cgaattggta caccagccgt tttgggctgt tgtgtgtccg ttgaatataa
    14221 ataaaaggtg ccttcatgtt caataatcgt aggatcatga accccattga tcgctgtcat
    14281 gtctttccct catctcctaa ttgatttata ctattttata aaaacaggac agctacttga
    14341 cgagctgtcc tgtttgttcc cacattcctg caggacagtt tttcttagct aagtttgcgc
    14401 gaaaccgata aaaacagcca catttggtac aggtatgatt caatcgcagt ggacaggtct
    14461 cacaaacagc gattctccta ctgacgatct ccggcaaagc caagtctctt tctaaagaaa
    14521 gttgttctgc aatcaaggat tcaatgtctt cctgtgctgc tacagcaaca tctttcactt
    14581 cgcatccttt acaagtcatg ggatcagact gtcaatgaga tcgttagaac actcattgct
    14641 ggcacacgca agctgacttt gttctcttca acatcgtaag cggtgaagtc ttggatcgcc
    14701 acatcttcag gatgatcaaa atcattgtgt gcgttcattt tgtctcccac gatataacga
    14761 gcttctttca ctttattgat cgctgtttca agggagaagg ataattcttc cgtgccttgg
    14821 gtagcaaaat tacaaaccga tagatggatc gtatcctctt ttttcgaaat cgtatacgta
    14881 atggtatcgc tgctggttcc atggctatca atggtttcag catcttgatg gactttgtac
    14941 aaatcaaata catgatagct tggggttttc accatttgtt cgccatctgt caaaatcatc
    15001 gcttgcagga cgttgacggt ttgtgcgata tttgccatgt gcactcgctt ggcatgttta
    15061 tggaaaatat tcaaggtgat cgctgcgacc atggcatcac ggatcgtatt ttgttggtat
    15121 aagaagcctg gattcgtacc aggttctgct gagaaccaag tgccccattc atcaacaatg
    15181 attccgacac gcttttctgg gtcatactgg tccatgatag cgctgtggcg ggtcaataat
    15241 tcatccatgt aggctgcttt ttcacaggtc acttgccact ctgcctcatt aaattccaag
    15301 gcgctacctt tttcttccca gccttgcgga tgaacgtagt agtgcaagct taggccgtcc
    15361 atcaaccaat gggcgttttt catcagcgtt tctgtccaat gatagtctgc gacattcgct
    15421 ccgccagcga ctttgtagat ttttttgtca ccgtattggc ggacataggt ttgatagcgg
    15481 cgatacagat ccgcatagta ctctggccgc atattgccgc cacaacccca gttttcgttt
    15541 cctacgccaa aaaatttcat ttcccacgct tcttcatggc cattttctct gcgaagatca
    15601 gccatcggag aaatgccatc catcgtgatg tattccaccc attctgacat ttcttgcacc
    15661 gttccgctgc cgacattgcc gttgacatac gcgtcacatt gcagctgctt gatcaattca
    15721 aaaaattcat gggtcccgaa atgattgttt tcagtcacgc cgccccagtg agtgttgacc
    15781 atcgttttgc ggttttcttt aggaccaatc ccgtctttcc aatgatattc atcggcgaag
    15841 cagccgcctg gccaacgcag cacagggatt tgaatgtttt tcagtgcttc aaccacatcg
    15901 atccgcatcc catttttatt tgggatcggc gaatcttctc caacgtataa tccttcatag
    15961 atacaacggc ctagatgctc tgcaaaatga ccgtagatat atttgctgat cgttgttcct
    16021 gattttgtgt gtagaatttt gattgtcatt ttcctactcc tattctttga ttccccaaat
    16081 ggactcatta ttatcgccaa tcgttgaaaa cgttaacttt tgctgctcga attctgttat
    16141 ttcctgagtt aataagattc ctttgaaggt agtttcttca aaagtcaaca ccaagtatcc
    16201 cgcatcgtac gtccaagttc cggtcaagtc tccagtaacg tttccatctt tttgaaactc
    16261 gatcatctgc gtttttagca tggtcgttcc attgtcggtg ccatggttaa tgatttcata
    16321 gcgcccgata atttcatctt ctgtcaaagc atctgctact tgttcattgc ctcgatactc
    16381 atagggtgct ggaactggcc agccctcctc attcatatac attctgttga cccgcacttc
    16441 atgggcttcg gttccattgt taaagcgcgt atgatacacc aaggaccact gaccattctc
    16501 atcgatgatc gccgaattgt gtcccgctgc tcgatacccc atttgttgaa acgagaattg
    16561 atagttccca atcaatttga taccataatt cacattttgt tcacctttat ccaagattgg
    16621 gctatttcct tgggcatcaa ggtaaggtcc ttctggtttt tcagcgcgaa atagtcgcat
    16681 attgtaacca ccttttgctg ctaaaccacc gtaagtgacg aataggtaat aataatcggt
    16741 tttctcatca taaacaatgt agggaccttc tcctgattga tgatagccac ctgagagttt
    16801 aatcccaaaa tagcgatcaa tgatgcgccc atcttctgta gtgctatctt caccaggata
    16861 cattggtttt ccagtggctg gatcaacttc caataaaaag ataccgccgg accaagaacc
    16921 ataggtcatc catagtttcc cttcttcatc ataaaacaaa gcgggatcaa tggcatttgg
    16981 cgcataatcg gtgttatagg taagaccggc ttcgatagac cagttttcac taaaaccact
    17041 tatttttcca tctttgatca gttttgccaa atgagtattt tgatagtttg tattacggtc
    17101 actaccatcc gttgaatctt tttctgtaaa tccagaataa ataactgtgt cagaatagct
    17161 gtatggtcct tcaattgttt ttgctacagc taatccaatc gctgaacgcc gccaagtaga
    17221 actagctgag tagtaaagca tgtaggctcc tttgtctcca tttgaccatt cataatcagc
    17281 attccagatc acatctggcg cccaaagact atagccgcct tttgaatcaa catcatcata
    17341 tcctgcccat ttaaatgttt cagctagatt ttctttggta tttccataaa taatattgtc
    17401 ttccattgat tcatattcgt gagaaaaagg aacttcccac gttcgtaagt ctgatgtttt
    17461 tgcttgagca agatgtgaac caaatacata gaataattct tgattttcct catggatagt
    17521 tgtaattgaa gggtcatgga tcgatacccg ttccttagat gttgtttccc actccttttg
    17581 tataagctgc tcggcagctt cccctgtttg acatcccata agaaaaaaac tggtcaaaaa
    17641 aacaggtatc atcctactga tcatatttat ttttgtagtc atttttttcc tctctttttc
    17701 ttaagctttg attacaccag gttcgccaaa attaggcagt ccatttttat gccatgtaaa
    17761 tggctgaaca tacgcatgtc tgtttggatt ttccaatgga tcactataat catttttttc
    17821 tggtcgagcg tgataaacta aaatatcttg ctttccttcc tcatcaattg taaatgaatt
    17881 atgaccagga ccataaagag aattacgctc agaacttgaa aacactggtt cttttaattt
    17941 gttccacgag tagccattca acaaatcgct ctcttcatct gcccataaaa gccccatcgc
    18001 atagttttca tccgtcgcac ttgctgaata agtgataaac acttttccat ttctaatcaa
    18061 agcggcgggt gcttcgttta ctttgaagcc gattttttcc cattcataat aagggatact
    18121 cagaagaatc tgctttcctt tcaatgtcca aggattttcc atctctgata aataaagatt
    18181 ggaattgcct ggaatatttg gatctacttg tgcccagaca taatacaatc ggttcctatg
    18241 ttcaaatacc gtagcatcta aactgaaact ctcaaattgc gtcttgattt gtcctttttc
    18301 cacccactct ccttcaaagg gattttcttt cgcattttcg attgcaaaca tccgatgatg
    18361 atgctgatca tttctgactt ctccatgatc tgcagcagca aaatagatgt accattttcc
    18421 ctgaataaaa tgaatctctg gtgcccagat cagctcactc attgagcctt cggcatgagc
    18481 cgtccagatg acttttactt caccgtcagt cagtcctttc aaggttttcg cacgtcttaa
    18541 ttcgatttcc tgataccctg gttttgatcc agtgaagtaa taatatccat cggtatgctt
    18601 gtatatccat gggtctgctc gttctaatac aatcggttcc aaataatttt ctgccataaa
    18661 ttctacacct tcttaaaaaa ttccattttc cgtttttagt atttttattg ctttattttt
    18721 agacatatac atcgtcgtag ctagtaaata gaggacgaca ccaatcacat catagatgat
    18781 caaatggatg atgacacagg cgatcatcca acgtatcgtt cctttgttta tttgtttgtc
    18841 tcgcatattc ttcgcgttga tccaactgat aacgcccatc aaaatcgttg ctaatgcaac
    18901 gatcaacact acttttgaga tcatacctat aagacttgat tgtaaatatt catactgatt
    18961 ttgattttga aacgctgcga tcccttgttc ttcaaaccaa ggataatacc caaacatcgt
    19021 tacgagacca atacagacat cccagaccgc actggcacgt agtaagtttc tttccagttt
    19081 tcgattcatg atcttcacta tccttttatt cctgcattta agttcataga ttcaatgaaa
    19141 tatttttggg caaataaaaa cagcagtact gtgggaataa tggcaatcaa tgctgatccc
    19201 attaactggc caatcatccg ataattccca taaatgtctt gtaataaaag cagcccagcc
    19261 gtaattggca tcttactaac gtctgtgtac acgattactg gccataagaa atcattccaa
    19321 gagccagtga aagaaaagag tccggcaacg atcagaacag gtttgatcaa cggaacgata
    19381 atctctgaaa aaattgtaaa ctcatctgca ccgtccattc gcgccgattc atcaaactca
    19441 agaggaattc ccttcataaa ttgtctgaca agaaaaatat tccccattcc agccagtcct
    19501 ggaacaatca tggcaagaga tgaattgacc caaccaaatg tttcgatgat tttataggaa
    19561 ggaatcaaat tcacaacacc gggaaacatc gagatcccca tcaaaagata aaagattcga
    19621 tcacgatatt taaagcgcgt tctgccataa ccataagctg tcactgaaac aacgatcaca
    19681 actaagacag tgtgagtgac tgcgataaac agtgaattcc ataaccactg catgataggc
    19741 gcagtagagg tattggttaa aatcgctata tagttatcta atatccaatt tacgggtaac
    19801 aagcgaaacc cagtggagac gatttcggtc tgagaacgaa aagaagtggc gaagctaaaa
    19861 atcaatggaa taacccagat gatacataaa acgatcagaa acaaatatgc gatgatcata
    19921 ctaggtatat gtttcttttg tgtattcatt ttttaccccc ttaagtattg cttctatcta
    19981 aaagaaaata ttgaaatacg gacacacaca taatgatcaa tcctaatatg actgccatag
    20041 ccgaagccat ccctgcaatt gattcccctt gactaaaagc cagtgaacgg atatacatca
    20101 tcaatacagt cgtgctttga ttgggtcctc caccagtcat catcaaaggc tgtgcaaaga
    20161 cgttaaatgc cccagcagtt gtcatcacga tcgtatataa cagtggaaac cgaatagacg
    20221 gcaaggtcac gttcaaaaat ttttggaacg atccagctcc gtcgatctct gcggcttcat
    20281 aaagatcttc attgacaccc gctaaagctg agcgatagat gatcatgtta ccaccaatcg
    20341 ctccccaaat gctgacagcg aaaatcaaga tccacgcata aggttgtcgc gatgcccaag
    20401 agaaatcaaa cccaaaaata ttatttacgg cacctaatcg agagtgaaaa atcagtgacc
    20461 atatcaaaga accagctgat acagagataa gacctggaat atatagaacc gcttgaaaaa
    20521 gtcctttcag cttcactttt ttatgttgca gtgccgctgc aatcatcaaa ggaataatga
    20581 tctgtagtgg taccatgatc aaaacaaaaa taaaggtatt tttcaaacca ttccaaaatt
    20641 gagtatagaa agtggacgaa ctatcaaata acaacgtctt atagttgttt aggccgaccc
    20701 aaacaggatc agaaatcaaa ttccattgag taaatgaagc ataaatccca tagactgttg
    20761 gaatgcatac aaaaataata aagagaacca tatgcggtcc aatgaatgca attgaagccc
    20821 agttaatgct cttttttttc attcctttca ttcccttcca aaaatcagaa aggggataaa
    20881 attatcccct ttcaattatt tagccacttc cgcaatctta tcttctacat attgttgcat
    20941 cgttgctaaa ccttcatcca agtctaattc actgtatgca atatctgtgc aatagacgtc
    21001 taatgcctct aatacatagg agaaataaac atagtcaaag atataaagtg tatcttcttc
    21061 ctctgatgtt gaagtaaaga aggattgagg atattgttga taatcatcac tttctaaaat
    21121 gtctttacta gcgacaattt gtcccgcttt tgcccattca atcgaattcg tacgaacgaa
    21181 ttctaagaat tgcgcgatga cttcttcttt ctcatcggtt ctagactcac tcttcaacat
    21241 accaaacata tgggaagcag cccgatttgt tgcaatatca tcagatgttg aataaatgtt
    21301 tgtgacaccc caattcagcc cttcaacagc atcatgcgcg gttgaagtcc aagtaccatc
    21361 tgtggacaat agaacatttc caccttggaa catcagataa ccgtcttcgc cataaggagt
    21421 cattaaccca gcatcggtta gtgctttaat tctttccaat gcttctttca tttccggagt
    21481 attaacggtc ggattgccag cctcatcaga aatagctcct cctaaattac ggatctgagc
    21541 caaaataacc caggaaagta aggcattgtt aacaacataa tcgccttcgt ccattttccc
    21601 tgctaatgac atcatttcat caaaagtaac aatattatcg tctaaccaag aggtaacatc
    21661 atatttctct aaaaggtcct gattatagta cattgcactc gcatggatat ctaacggaat
    21721 tgtatactga gtgcctccaa ttgttcctgc attccaagca gtatctaaat aattgccttt
    21781 ttgtagctct ggttgatgcg aaaccaaagg ttcaaccgta tcgagaatat tcgaattaac
    21841 aaattcctct actttgtagg aatgcattaa tgttaaatca ggaataccat ttttagagct
    21901 aacgactgta cttaattttg tatacatatc agatgtgatg acgtgattaa ttttgtaatc
    21961 tgatccagac tgttcattaa attcatctac aatcttgtcc atataagcac catcatcccc
    22021 cgtaagagga gaccaaaaat ttattgtgta tttttctttt tctgaagact ggtaacgttt
    22081 aaaaccggca aaagcaattg cgactactgc aaccaatgca ccaataataa taagtttctt
    22141 cttcatgttc ttccctcttt cattgaaatt gaattatgac ctagccgaac actcctatcc
    22201 tcctcatcac tatttactat caattcgtat ataatttcat tacttattac caaaatttgc
    22261 aaacgttttc tatttgcaaa taaatcataa ctttatttgt aaccgctgtc aacaacattt
    22321 taat
//
LOCUS       DADVXB010000038        21746 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.038, whole genome shotgun sequence.
ACCESSION   DADVXB010000038 DADVXB010000000
VERSION     DADVXB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.038"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            44..1384
                     /locus_tag="KB902_001105"
     CDS             44..1384
                     /locus_tag="KB902_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6807946.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTFW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1602..2045
                     /locus_tag="KB902_001106"
     CDS             1602..2045
                     /locus_tag="KB902_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6807947.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2549..3967)
                     /gene="nhaC"
                     /locus_tag="KB902_001107"
     CDS             complement(2549..3967)
                     /gene="nhaC"
                     /locus_tag="KB902_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6807948.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4370..5593)
                     /locus_tag="KB902_001108"
     CDS             complement(4370..5593)
                     /locus_tag="KB902_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBB6807949.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5624..6463)
                     /locus_tag="KB902_001109"
     CDS             complement(5624..6463)
                     /locus_tag="KB902_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6807950.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6480..7160)
                     /locus_tag="KB902_001110"
     CDS             complement(6480..7160)
                     /locus_tag="KB902_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6807951.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7162..8235)
                     /locus_tag="KB902_001111"
     CDS             complement(7162..8235)
                     /locus_tag="KB902_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6807952.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGFEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(8291..8529)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(8572..8805)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8882..9553)
                     /locus_tag="KB902_001112"
     CDS             complement(8882..9553)
                     /locus_tag="KB902_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6807953.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9640..12318)
                     /gene="mgtA"
                     /locus_tag="KB902_001113"
     CDS             complement(9640..12318)
                     /gene="mgtA"
                     /locus_tag="KB902_001113"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBB6807954.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            12977..13414
                     /gene="ndk"
                     /locus_tag="KB902_001114"
     CDS             12977..13414
                     /gene="ndk"
                     /locus_tag="KB902_001114"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBB6807955.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13436..14302)
                     /locus_tag="KB902_001115"
     CDS             complement(13436..14302)
                     /locus_tag="KB902_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6807956.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14462..16555)
                     /locus_tag="KB902_001116"
     CDS             complement(14462..16555)
                     /locus_tag="KB902_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6807957.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(17304..17927)
                     /locus_tag="KB902_001117"
     CDS             complement(17304..17927)
                     /locus_tag="KB902_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807958.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(18086..19483)
                     /locus_tag="KB902_001118"
     CDS             complement(18086..19483)
                     /locus_tag="KB902_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6807959.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(19515..20486)
                     /locus_tag="KB902_001119"
     CDS             complement(19515..20486)
                     /locus_tag="KB902_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6807960.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            20860..21285
                     /locus_tag="KB902_001120"
     CDS             20860..21285
                     /locus_tag="KB902_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807961.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         6269 a         4494 c         3772 g         7211 t
ORIGIN      
        1 taatataaat tttgattatg aatttaaaag aaagaggtca tttatggaag ataaaaaatt
       61 gaaaaaacaa cttagctcca gacatatcac catgttagct ttaggtggag caatcggtgc
      121 aggtctattt aaaggaagtg gcgaagcgat tgggatcgcc ggcccttctg tattgattgc
      181 ttttttgatt ggtgggctga ttttatatat cgtgatgaaa ggtctgggaa aaatcgtttt
      241 aagcggtggc gacacgcatc acggattatc tggtttgata cgcccttatc taggtgctca
      301 ttctgctgat tttactgatt gggtctactg gtctatgtgg attatcaata tcatcgctga
      361 agctgttgca gctgcttcct ttttgcagtt gtggttcccg cacattccag cctgggtatt
      421 tgtttttatg ttggctgttt taactacgat catcaatctt tattcggtac ggttattcgc
      481 agaaacagaa tattggctgg cttttgctaa aatcagtgtc attatcttac tgatcatttt
      541 tgctacttat cttgtcggtc agcaaatgtt gggcacaggc gttttcccta cccttcagca
      601 attgactgac catggtgggt ttactcctca tggtatgaag ggaatcatca gttctttgct
      661 tgtagttatc tattcttacg gcggttctga actgattgct atcacggtaa gcgaagcaga
      721 tgatcctaaa cgtgcgattc ctaaagcaat caaaggtgtc atgggaagaa tcatttcctt
      781 ttacatcatt cctttgtttt tgcttttgat tctttttcct tggaatactt tagcaggcac
      841 gaatgtcagt ccttttgtga tggtatttga aaaaatgaat atcccatttg cagcggatat
      901 cgtcaatttt gtgattgtcc ttgctttgtt ctcatctatc aattcgggtg tgtatgcatc
      961 ttcaagaatt ttgttcttcc gtttgaagga tcgaaaaggt tcctctagaa aactagctgt
     1021 tttaaacaag catcaagtac cgcaacgtgc tgttttattt tgtaccagtg ttctttatct
     1081 tggtgtagct ctttcttatt ttgtcggtga caaattattt ggctatctgg caggttccct
     1141 ttcgtataca gtattattga tctggatcat tatcagtgcg gcatcctttg tactggcact
     1201 aagaaaagga acattttggg ataaaggaat cagctttttt gcattagctg tcttaggatt
     1261 gattttcctt ggtatcctgt tcacgaactc cattggggta actgtattga ctggcctgct
     1321 ttacctgttc atttatttca gttatcaaaa aaagaatgat gcgttcgtat tgacgaatga
     1381 atgaaatcga tagaaaattt tattttattt atgtggaata gatggagcta ttgaagaaag
     1441 gagttgtgac aaaagtcttg ttgcaactcc tttttccgaa taaacagtct catgacctct
     1501 tggtaaacgg tgttcaaaaa ccctctgtgc aaaataattg attgttctcc atgctcatga
     1561 catgatagaa gaaaggaatg aaaaaaagga gtttgtttta aatgaaaaag tattggaagt
     1621 ttttgttgat gatcggtgtt tcaacggtag ttatgtttgg tatgatgtac ttgaatgtct
     1681 atgcgctcga tcatatcttc ttcagtcgta cacgagtatt catggcgttg atgatgggtg
     1741 cagtcatggc agtcatcatg ctgttgttca tgtggaaaat gtatgaaaac aaaaagataa
     1801 atgttatgat cttagccgct agtcttcttg tttttgccgg ttccttgttt atggtacgaa
     1861 gccaaactac tgtcaacgac acagcttgga tgaaggccat gattcctcat cattctatcg
     1921 ctatcctggc aagtaaacga gctgatttaa aagatcctga agtaaaaaaa ttagcggaag
     1981 aaatcattca ggcacaagaa gaagagatcg acaaaatgaa aaaaatgatc aaagaaatgg
     2041 aatgaccatt atccgtccaa ataaaaaaag aggatgttcc agaagttatc agcttcaaga
     2101 aataagaaga agctacttct ggaacgccgt gaataagggg ttgtgaaaaa gctgccctgc
     2161 atcaagtaat aagaacagcc aaacaaaaat agcttctcct atttttcgtt tggttaggct
     2221 tattaccgca gatgcaagct tttgaacacc gtttattaag aggttgtaaa atcagcgttc
     2281 tgacctgagt attagagaga caaatggaaa aatagttcct catattttgc cattttttga
     2341 gctaataccg agggtcagct gattgaacac cgtttatcga gaggttgtga aaaagtcgct
     2401 tagtttcgcg tattaagaaa aattttgtga aatggctttc cacatttttg tataaatttg
     2461 gcttaatacc gagaaactgg cttttgaata ccgtttattc gtaaaaggga ttgtgacaaa
     2521 agtcttgtca caatcccttt ttatgttttt attgttctaa ttgcgctgtc ttgcttactg
     2581 cttcttgcgg tttcacaaat ttttttgaga ttccccaacc tgtgaaggca ctgaccatcg
     2641 aaaacacagg agaaagcaaa ctgaaaaata cgaatggcaa gtaagtgagt gtaggaatac
     2701 caaatgtact tgctacgaaa cttccggcaa ttccccaagg cactaagtag ttgattactg
     2761 ttccaccatc ttctagcgtt ctacctaata cagttggatc aaatcctgct ttttcataag
     2821 tttctttaaa tgcattacca ggcagaataa cagataggaa ttgttcacca ataaaaatat
     2881 ttactccgat acttgtcatc aatgttgtaa aaatcaaatt tggtgtgttc gtcatctttc
     2941 ttgatactcg ttccatcacg gttgagatca agccaaattc gatcaacaat ccacctaatg
     3001 acaaagttag aataatcaat gacacagtag gcatcatact ttcgattcct ccgcggctaa
     3061 gcagtgaatc gatttgttgg tttccagtat ttgaaacaaa ccctgattcg atgaccccag
     3121 ccaacttcgt taaggaagtt tgtgggtttt gaataaaaat cattcctact gctacagcga
     3181 tattcaacaa aatcgttaaa attgccggca cctttttcca tgcacacagt aacattaaaa
     3241 ataaaggaat cagtgaccag attgaaatag taaagtttgc ttctagaaca tcagtcactt
     3301 cacgaataga tgaaagactt gcggctttac ttgtgtgtcc taaaatcatg aataaaaaga
     3361 aagaaacaac aaatgccggg acagttgacc acatcatatg cttgatgtgt ttgaacaaat
     3421 cggcatcaac aatagctgct gctagatttg ttgattcgga taatggagac atcttatctc
     3481 caaaaacggc acctgaaaca atagctccaa caaccagcgc tggatttaag cctagtgttg
     3541 tcccaatacc gaaaaatgca atcccaatcg ttgacataac agtaaaggca ctccctacag
     3601 cgctacctac gattgcacac acaacaaata cagaagggac aaaccactgg acactgatca
     3661 atttgaaccc aatgaccatt agagttggaa tgatccctgc ttgtatccat acagcaatca
     3721 atgaaccgac taaaataaaa ataaagattg ggatgattcc tggtttgatg ccattgatga
     3781 ttccttcgtg cagccaatct gtcgggtatc tttttatcac tgcatacaac atgaccattc
     3841 cgatcgctgc taagatcgtg atattaggtg agacctttaa tccgacaacg ccaatcgcaa
     3901 tgcctaaaac aataaccatt aatacaagtg ttgcttctaa aaaacttggt gttccttttt
     3961 ttcccatgat aatctctcct tttttagttg ttcttatgtt ctaaaaaagt taagatatcg
     4021 gattactccg ccgcaattca tccgcgattc ctcctttata aaaataaaaa gacctgtttt
     4081 aaactaagga cgaatgactc cgcggtacca ccttaattaa aaacagatct gtttttcact
     4141 ttcaaacttt tattcaaatg tatggacttt ccatgtaatt cgtcaattag gcttgatcgg
     4201 ttcacagcga ccaccgactt tctgaacaaa acacctaacc gctactgcgt gaaaagttga
     4261 cttgtacgaa gtttaccttc cataagatca tttgtcaatg aaaaagaaaa tattttttca
     4321 tttttctgaa aattattttt ataactttca cacacaagtt tattttttac tagaaagtag
     4381 cgccctcttg tttttttctt gctactattt cttgatgttc ttgcttgatt ctttctaata
     4441 gctttggctc tttcaacaga tcaagagctg tattggcgag tagttctgct gcaatcgcaa
     4501 tagaagcaag gcctttgtca cttttagcag cagctttgaa ttcttctgtg tgtccggcaa
     4561 tatatgtctc agagattgct accgtaggct ggattgttgg tatgacttgg ctgacatttc
     4621 ctacatcaga agaaccgaga cttgttcttt gttccgtttc tatttcttca tctggaacac
     4681 ctgcttcttt tgcatgctgg aagaataagt catcaaaaga aggagtaacg atgacatcat
     4741 caactgcatt ttggaacaat ccaaactcaa aagtcgtgcc cgtacttatc gcagcacctc
     4801 gtacgatatt ttccactttt tcatatactt tatctaatgt ttgccgattt cctgcacgta
     4861 aatagaaacg tccagcagcg taatctggaa tgacgttggc agctactcct ccgtctgtaa
     4921 tgatcccatg gatattgaca tcttttggca attgcaagcg tagagcgttg attccattaa
     4981 acacttggat caatgcttcc aaagcattta ctcctttttc aggtgctgct gctgcatggg
     5041 aagcgacacc gtaaaatttg atgtcgactg gatcattcgc taaagattct gtcgttttcc
     5101 cataacgaaa agctggatgg acgcataacg ctacatcgac atcctcaaaa aaaccttctc
     5161 gaacaaagct gcctttagct gatccgttct cgcccccttc ttcccctggg gtgccatata
     5221 cacggatttc tccaccagtt tcatcaatga attgcttcac tatgctggcg gctaatacgg
     5281 agtaagtacc aaacaaatta tgcccgcatg catgaccaat acctggtaaa gcatcgaatt
     5341 ctgccaaaaa ggcaattgtg ggaccgggtt tattggaaat ataacgtgca tcaaaggctg
     5401 ttcggtgtcc agctacttct ttttctaccc aaaacctttc tttttctaat tgtttaatca
     5461 acgctgctga ggaataaaac tcatagttac ttacttcagg atgttcgtgg atatctagag
     5521 caagtgcttg atattctggt aaacgatatt ggattagatc cttcaattgg tttgttgaga
     5581 ttgttgttgt cataaaaaat tcctcctatg ctagtcattt ttcttatttt ctcccgaatg
     5641 tttcccatgc aggcacgctt gatccttttg atgttttctc gattactttg actgtgtctt
     5701 ctgtttgata agcgtctact attttttgat acgttttatt gttttcatct tcttttcttg
     5761 caacgatgat attcacataa ggacgtgcat ggtcatccac tggttctaag aagatggcat
     5821 cagaagcagg attaaatcca gcatctacag ctacaccgct attgatcact gaaatgtcta
     5881 catctgacaa agcacgtgct gtttgggaag catctaattc agaaatgtct agattttttc
     5941 tattctcggt aatatcagaa acagtgggcg cttgtccttt tgccttatcc actttgatca
     6001 atccagcagt ttgcaataac agaagagctc tgccgccatt tgtaacatca ttagggattg
     6061 ctacttttgc tccgtctttg atatcagcta catccttcaa agtgttagaa taaattccca
     6121 gcggtgcatt gacagtattt ccgatcgata ctaaatcagt tccgtgttct ttattgtaat
     6181 tgtctaaaaa gaattgatgt tggaaagaat tcaaatcaat cgatccatct gctaaagcca
     6241 catttggttg attgtaatct gtaaatttca cgtattccaa attaatgttc tcctttttca
     6301 aacggtcttt cacgttgtcc catacatctg tatcttctcc aataatccct agttttacga
     6361 tagtttcttt tttgtcagtt gtatctgctt ttccttggct acaccctgcc aaccaaataa
     6421 ttgctacaaa tgtaatgact acaaaacgaa taattttttt cattttttct cctccacttt
     6481 caatgtgtaa tttttttaat cagttgatta ctgataaatt gacttaaaaa aactaagatt
     6541 agaatcaata atgtagccac aatcgttaca tctgtttgga atcgattata ccctctcgat
     6601 atagcaagat tccctaatcc gcctgcacct actgctccag ccatggtagt cagtccgatc
     6661 acgttgatga tagtcaacgc cgagacccga atgataccag gcaaaccttc taacaaatac
     6721 acacgtaaaa tgataccgat tggactggtt cccatcgctt ctgccgcttc gatcacccca
     6781 ggatcaactt ctagcagtgc gttctcgatt tgacgagcaa aaaacggaac aactccaaaa
     6841 atcaatggca ctaaagctgc tttcgcacca atcgtcgttc caactaagaa acgagtagtc
     6901 aatgctaaaa gagaaagcaa gataatgaaa gggatggaac gaatgatatt gatcagctta
     6961 tcaagtattt caaatagcag acggttagct agtaatccat tagggcgtgt cactactaac
     7021 gtcacaccta agatgattcc aatcatcccg ccaatgaatg ctgtccaaaa agacatatat
     7081 agtgtttgct tcgtcgcttc gacaaattca tccggaatca aataaacatt gggcaaatat
     7141 gttttaaaga aatcagtcat tttatcttcc tccttcgatc actttgatac gactatctaa
     7201 atcgtttttt tgtaaaatat ttatttttac accagatttg atcaaataat ccaatgcttt
     7261 tttccgctgt ttggtttctc cagctaaagt aacgatcaaa ctccctaacg gcgtttcttg
     7321 taataactct acattgccat ataaaatatt cgctgttact tgatatttgc tgtacagatg
     7381 agcgattaga ggttcgttcg tctgatttcc aatataactt aattccacca gccatttatt
     7441 ggcgatctga tcggcaaaag cagaatgggc aatgatcgtt tctaatgctt ggtcaagatg
     7501 agtagctgtt cgaataaaat ctttggtcaa ttcttcttca ggattgctga agatctggat
     7561 gctgctacct ttttcaacga ttcttccatc ttccataacc gctaccttgt tgcagatttc
     7621 tttgacaact tgcatctcat gagtgatcag gacgattgtt aaacctaact ggcgattcaa
     7681 tttttttaac aatgcaagga tctgaagggt cgttttcgga tcaagtgcac tggttgcttc
     7741 atcacataat aataccttag gttcattcgc caaagctcgt gcgattgcta ctcgttgttt
     7801 ttgtcccccc gacagttgtt taggataagc agatgctttt tcttcaaaac cgacaagttc
     7861 cagtagttca ttcacttttt gacgacgttc ctgtttcgat tttccagaat actttaaaga
     7921 aaaatcaacg ttgtcaaaaa tagttcggct ttccattaga ttgaaatgct gaaagatcat
     7981 accgatggcc tttctttctt ttcgcaattc tttgggagag agctgactca gattcgtctg
     8041 attgacaatg acttctcctg ctgttggttt ctgcagcaaa ttcatcacac gaactaacgt
     8101 acttttccct gcacctgagt aaccgacgat tccataaaca tcgccttttt caatcgttaa
     8161 atctacagaa tctactgcct gtatctcttt ttctttttgt ttgaaacata cagaaacatc
     8221 tcgcaattca atcattaaaa ttcctcctta tctaaaaaaa gcgtcctcaa gaaaatgaaa
     8281 atgtcatttt cttgaggacg cttttttgcg tgttaccacc tcatgttcaa gctgtgttca
     8341 cacacaactc ctcttcaagt acgatcatac tctagcaaga tatcggtcgc agccgtcatc
     8401 gccttacatc tatgctcggg atgaattgct cgatggccat tttccaatag tcgttccttg
     8461 cttcttctca gctaccgaag ctctctgtca aaggttcttc tatcgtactt accatttcaa
     8521 tgcaaataat attcaaaaaa aaagtccttt tactaacata aactatgtca gtaaaaggac
     8581 gacgtatcgc ggtaccacct tttttcggaa gtttccttcc ctcaagccca acatctcaaa
     8641 aagagagatt ggcgttcgtt ttaacggtcg aacagttccg aatttgccta cttatcgaca
     8701 aattattctc caaggccatt ttcagctttt cttacttgac tcttctcacc agccagagcc
     8761 tctctgcaaa gtttccaaac ttactttcct tttcaacgaa atcgatattt tgttgttggg
     8821 attaatctac atgaggaaaa ctgaaaagtc aagtacgaaa ttcaaattat tttttctata
     8881 tttatttttc tgttttttta tttaacattt caataacagt tcgaagatct tttccttccg
     8941 caagaagttt caatttttcc ttttcttcga cggtataatt tcggacaaaa ctggaatcag
     9001 gtatcaaaac aacgcctaat cctgctcgtg aagcagctgt tgctcctact aaagaatctt
     9061 ccactgcaaa ggctgaacta gcttctaatc ctgttcgttc caaagctgtc agataaggaa
     9121 tcggtgaagg cttgttctcc gacacttcgt ctccgaatgt aaacgtgtcc aagtaatcag
     9181 ctaatttaaa gtgatccaag atatctgttg ctcttttcgt aacagtggtc gtagcaatgc
     9241 ctagtttcat atgacgttct tttaagtctg ccaatatttc ttttgcatat ggttttaagt
     9301 ggatggctcc gcttgtcagc tgttgataaa aatattcttc acgcttcgct cggacttcct
     9361 gtactttttc agggctacct gctgctttca ctaaaatatc aaaactttgt ttccagtttt
     9421 ttccgcccca agcgtcaacg atttcttttg ggatatggat atcaaattgc tgaaatcccc
     9481 aaagccagcc atcacgatac gttttttctg tgtcaactaa caaaccatct aaatcaaata
     9541 ttgcaccttt catctataca ttaatccttt ccaaaacaat acacatagtt tagcacgact
     9601 ggtccaaaaa gaacagaagc aaagaaccag ccttctcgtt tataagagtt cttggaatcg
     9661 acggatatag attttcttca cagctgtcac aagcgccaga taagcgatga ctgtagcaaa
     9721 taaccataac cagtaattgc caggaagtgg catcaagcct aattcagcac caaaacttgt
     9781 aaaaggaagg acagaaccga caataattcc taatgtagtg ataacaaaca tggcaaatgt
     9841 tgcgttgctt tggataaatg gtactttcgg tgtacgcagt gcatggagca ctaaggtttg
     9901 tgtccatagt gattcgacaa accatcctgc atggaataat gcgatgaaaa tcactcgctg
     9961 tgaactatcc aatgtatgga aacttccgcc cactacagca ggacaaataa caaaatacat
    10021 caacaagtaa gtagtaatat caaatatcga acttgttgga ccaaagtaaa ccatgaattc
    10081 cccaatacta gatgcattcc atttttttgg ctcgtccaaa tattctttat ccatccgatc
    10141 ccatggcaag gaaatgcagg aaacatcata gatcagattc aaaaacaaaa gttgtaaagg
    10201 cagcattggt aaaaatggca ggaacgtact tgcaatcagc acggaaaaca tattgccaaa
    10261 attagaactt gctgtagcct tgatatattt catgatattc ccaaaagttt ctcgtccaga
    10321 aagaaggcct ctttccaaaa tcgtcaaatc tttttctaaa aggatcacgt ctgcagattc
    10381 tttcgcaata tccacagctg tatctacaga aataccgata tcagccactt tcattgcagg
    10441 agcgtcattg ataccatctc ctaaaaatcc gacagtatga ccatttttac gtaaagctgt
    10501 cgtcaaacgt gctttttgct gaggattcaa ttttacgaat acttcatggt cttcagctac
    10561 ttgtgctaat tcatgatcac tcatttccga gattttctca ccggtaacca attcattgat
    10621 ctctagacct acttgacggc acactgaacg tgtaactaat tcgttgtccc cagtcagaac
    10681 ttttacagct acaccatgtt ctttcagagc tttcaacgct tgtttcgttg tttcttttgg
    10741 tggatcaagg aaagcaagat aaccaatcaa aaccatgtct gactcatctt tgactgaaaa
    10801 ttctccaacg acgcttggat tggtcttttg tgcgacacca atcactcgta agccatcttc
    10861 attaagtgac tgtacttttg caagtacggc ttcttttcgt tcttttgtta atggtgtaac
    10921 agtaccgcca agatcaataa atttagaaat gttcagcatt tcttcaatcg cgccttttgt
    10981 gatcatttgt gttttaccag ctggatcagc aaccacaaca ctcatacgac gacgttcaaa
    11041 atcaaaagga atttcatcca ctttttgata attgatctta tctgtatcta aagtttctgt
    11101 tgcttcatca atgatagcca catctaacaa atttttcagc cctgtttgat agtagctatt
    11161 tagatacgca tggcgcaaaa cacgatcatc ttcatttcct tcacaatcca tatgatattc
    11221 aagaatgatt ttatcttgtg tcaatgtccc cgttttatcc gtacataaca catcgattgc
    11281 accaaagttc tggatggcat tcaaattttt gatcactgtt ccttttttgg ccatcacact
    11341 tgctcctttg accaaattcg tcgtaacgat cattggaagc atttcaggtg ttagaccaac
    11401 tgctacagat agtccaaaaa gaaaagcttc tagccaatcc ccttttgtaa gcccattgat
    11461 gacgataact gctggagcca tcaatgacat aaatttgatc agtagcatgg atgttttatg
    11521 gatgcctaat tcaaagcttg attgaattgg tttttcagat agcgtttctg ctacatgacc
    11581 aaatagtgtt tcatttccaa cagaaacaat gattccttcc gcacttccac tgatgacatt
    11641 acttcccata aagacaagat tttcgtaact tgtttcgctt tgctgatcgt cttcacatac
    11701 tttcgcatgc ttttctactg gatagctttc ccctgtcaat gctgcttggg aaatgaataa
    11761 atcctttgcg gacaataaac gcatatccgc tggtatcata tcccctgctg aaagccgaac
    11821 aagatctcca cagacgattt cttccatagg aatctctgtg tactttccat tacgttttac
    11881 agctgccgtt actttcacaa gtgatttcag tttttcagcc gcttgattgg aacgtacgga
    11941 ctgaatcaac gtcattgtcc cgctgacgat aaccatagtg aagataatgg ctacaccgaa
    12001 aagatcttta tctccaggag ctgctaatac atattccgtg atgaatgaaa taattcctaa
    12061 tgcgatcaac actaatgtaa atggcgtgat gtatgctttc aatatttcta caatgaatgg
    12121 tgtttttttg ccatatgaaa tcgcattttc accgtaattt tctcttgaac gttcgatttg
    12181 ttcttctgtc aatccatttg ctgatgcatg gaatagttca aataattctt gtttcgtttt
    12241 tccagcaaaa gctgcataga ttttttgtgt atctttcttt ttttccatct caatctctcc
    12301 tttgtgtcca aaagacagct gttctcgctg cttttggtct ttagctattc atcggatcga
    12361 tagagaaaaa actgaaaggg gctgagaaca gatagataat agccctggcc tttcctctag
    12421 atccttgttt ttcgaatgac tgtcatccat ttgttctcat ctcctttact aagtaatttt
    12481 aattcatgac ttccaatcat ttttcgaata gttatttttc caattagacc acctcctttt
    12541 tatttttcac cgatggggat ttgcggcaac aaaaaaacct ctcgccaaat actcagcgaa
    12601 aggtttgaaa aagcatatta aaaaaagctt ctcagatctc atcgttgagt tttgacactg
    12661 tacaacgtaa aaagcagata cctgctttta gctaccttat gaaaagcctt atctcgacaa
    12721 ttcctgttct acccattggc gtctctcgac gtttttgggc agtagcctat gtttgtatag
    12781 gagcctcacc taacaaatct tattcggttt tccttcgtta atataacaac taaaaaagag
    12841 gatgtcaaat caattttcca tgtttttcat acttttttta aaatacacac gttatattcc
    12901 tgtctcacgc ggttttattt gtctcatttt ccacctcccg ctataataga aatatagtag
    12961 gaaacgaggt gctgttatgg aaagaacact tgttattatc aagccagacg gcgtgagacg
    13021 ccatttagtc ggaagcatca tccaacgttt tgaagcaaag ggactggcca ttgctgaaat
    13081 gaagtttgaa actatgactc ctgaattagc aaaagaacat tatcagcact tgactgagcg
    13141 cagttttttt gatgaactga tcgattacat gacttccggt cctgtcgttt atcttgtgct
    13201 ggtcggcgag gaagtgatcg atatcgtccg taagatggtt ggagcaacaa aagctgccga
    13261 tgctgttcca ggtacgatcc gaggagacta cgcgctgccg gggactgaaa acatcattca
    13321 cgcttctgat tcccgtgatg ctgcggtaaa agagatcgcc cgctttttcc cgccattcga
    13381 tataaacaaa ccgtctgaaa aagcggcgaa gtgatacaaa ttctaaactg ctggtctagt
    13441 tgctgggttc agcaatggcc agcagttttt tctctaagga cctccgttga ttctttccta
    13501 acatatattc gagcactgtg aagaattctt ggtagtcttt cgtcttttct tcccctaaag
    13561 cagcagaaat caatctttga taataatctg ccatcaatgt ttcatagatc actgtacttc
    13621 tttctttatg tgctaagctc cgtttcatat cttcattcac actacgtgcc tttttcaacc
    13681 gaccattttc tatataaaac gaagtcaggt tcattaaaaa agtaaagaga tactgctcat
    13741 gattgttcaa ctgtgctaat cgtcgcattc tttttttgat tttcaaataa ttgttctcaa
    13801 tgaaccgatc actgaatatc caaggaaaat cagctagaat agatagttca aattgaccat
    13861 agtctggtat ctgcatcaag tattcttcaa tgattcggca ttcataacgt aaaaattcaa
    13921 attctgtctc agatacttct gttttttcga ccatgtgaag attcaaaacc aaataataca
    13981 gatcttctgt tttcttaaaa tgcctacggt tattgctgat ctctttataa ggatcaaagc
    14041 tgtcttcttg tacccgatct agcattcgtc tttttttctt taactttatt ggttcatcca
    14101 gctggtttcg catccattca tattctgcaa gtgtcatgtt cattcgctct aaaaatgatc
    14161 tcaatgttac aaatgacatt tttttcactg aatttgtctc aatcccgact agagaagtct
    14221 taaaacagat tccttccgct aattgggact gtgtcaactt cttgttgact cgaagtttct
    14281 tgatcaattc accatcatac ataatagttc tcctttttaa tttaaatttt tccacattca
    14341 ataaatagat acgttaaaaa ggaaaaatac acgaaaaaaa taaaaaaatg tttttttcat
    14401 aaaaaatacc aaccttcaag cattagaatg ttgtctaact actgaaggtt ggtttgattg
    14461 tttattgatt atttttttgc tgttcaacgt ctgttcttgt tactggatat aagttggttg
    14521 ttgttttatt accatttttt gaaaagacac ttgtcgaatg ttcgcctttt tgcttttcga
    14581 ttgcttcatt acgttccgct tcatttttat agtcatattt tttcggatca atcgtctcaa
    14641 atccgtttgg cacataaaac cgcaagagat tttcctgatt cagcttatct gaaagactta
    14701 acgcagtctt gactttttcc tgatctttgg agatttcctc atcgattcct gctgctttcg
    14761 tatcgatgat ttctcctgtc tgattattgt aagcttttcc tcctaggacg gtgtatttgg
    14821 gtgtcacaaa gttcccattt cgaaaagcaa ctacttgatc atgctgagaa gataataagt
    14881 ctgtaccaaa atgaagataa tctttatcat cgattcccaa tagatgtagt aatgtcggca
    14941 aaacatcgat ttctccaccg tattcatgat tgactgtccc tttagtataa ccaggcatat
    15001 ggatcatcaa tggcactcgt tgcatctgtg cgttgtcaaa ttcatcccat gtatctggat
    15061 ctttaccaag agcgcttgct aaatctttat tatctgtatt cgagatccca aaatgatccc
    15121 cgtaaatcac aaagattgaa ttttggtaaa taccagattt tttcaaatac gtaaaaaatt
    15181 gttccaatga ttgatccaga taatgtgccg ttcgaacata attatctact gtgctattgc
    15241 cagtattcaa agatggaaag tcgaaattct tgtcatccgt ataataaggc gtgtggttgg
    15301 ttacggaaag aaatttcgtg taaaacggct gttgtagatg ctcaagatat tgggcagatt
    15361 ctctgaataa atctttatct aatatcccat aacctaacgt ttcgtcggat tcatcaaaat
    15421 aagatcgatc aaagaaattg tcataaccta agtttttata tacatgatct ctattccaaa
    15481 aactagctac attcccatgg aaaacagcgc ttgtatagcc ttgcttttgt ccaaggatcg
    15541 ctggtgcggc ttgaaagaca ttgtctgacc caagttctgt gaataatgag ccttgaggta
    15601 aaccaaatgt gccagtttcc aacatatttt cagcatcact tgtctttccc tgtcctactt
    15661 catgaaagaa attgtcaaag ctgatcgttg cttgattctg gaaaatacta tttaaaaacg
    15721 gtgtgacttc ttgtccgtct accttcatat taatcaaaaa ctgctggaaa ctttctaaat
    15781 ggagaacgat cacatttttc cctttagcga tcccaaatgt ttcgggattt ggctctgcat
    15841 aatgtttctt tgtataatct aaaacttcat caatcccatt actgcttgca tgcgcgcgaa
    15901 cactgctagt cattcctgtt ttgattccgt cataaatagt atacgcatcg attcctagat
    15961 atttgacaat atatgaacgg tcaaatgttc gctgcagcaa ttgtggacgg ttggcttcgc
    16021 tcagcgctag atttcctgaa aaaataagcc ctgaaagaca ggtaacagcg atagccatcg
    16081 gtttgccgac agggttgctt ttgataggta ttttcttgac cttcaaccaa accagtagcc
    16141 caatgaacac agcgatatcc agccagtaga tgacatcatg gggcttcatc aaagaaaagg
    16201 agcttcctga caatccttgc gacactttcg aaaagcctaa tacagatttg actgtaatga
    16261 aatctgtgaa ttcccgataa aaaataatat tcaagtacaa caaaagcgta tttaaaatat
    16321 caatgatcaa aagaatagct aacgctggct ttggcttttt aatatacaaa gaaaggccaa
    16381 aaaacaataa ggtagtcgca attgggttga tccacaagat aaagtactgg atcgtacctt
    16441 ccacacctaa tgaaaaatct gcatagtagg caatgatcgt cttcagccag aaaaagaaaa
    16501 cagctgtcaa aacgattgct aaacgatttt ggcacaattt tttaagttgt gtcacgtata
    16561 tcacttctct ctattcacat tttttcttat tttgctcctg aaaaatgaaa atttcctaaa
    16621 aaagttgtta tcttaagatt tttttattct ttctaaagat tattccgtcc acttttcaca
    16681 gcataaaacc gctgcgatgt aagcgattaa actaatgaag agataaaagt cttgtggtga
    16741 ccgcttcact ccacggtatt caaaagccag tttctcggta ttcgtacaaa aaaagaggct
    16801 gtgacaaaat tcttgtcgca gctccttatt tcttgatgca ggacagcttt ttcacaactt
    16861 cttccttaaa cggtgttctc ctgccaactc ctcggccaca agtcacaata tttataaaac
    16921 atgagaagct gttttttgaa attgttcctt gtggctcaga gttaaacggc aggctcaaga
    16981 cctcttgata cacggtgttc aatcagctga ccctcggtat tagattatgt caggacgcta
    17041 attttacaac ctcttggtaa acggtgttca aaagcttgca tctgcggtaa taagcccaac
    17101 caaacgaaaa atataaggag ctattttttg aaattgctcc ttgtggctca gagttaaacg
    17161 gcaggctcaa gacctcttga tacacggtgt tcaatcagct gaccttcggt attagctcaa
    17221 aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc aggtcaaaac
    17281 gctgatttca caacctctgt ttttcattgt ccataggatt gatattgtcc ttgtgatgac
    17341 tcattcgtaa taattgaggc ttgattttct tcacttcccg ttatcgtttg tccactgcca
    17401 gaatctgaag gacttgttcc tgtcgactcg tttttttgag aagagacagt tgttttcttg
    17461 acttgttcat ttgtcttttt ccattccgct aaacgatcgg cgaccacttt tttgtctact
    17521 ttttcagaat aagcggtgat cacttttcca tttttcaaac gggctacttt gtcgccatca
    17581 tgagtcaaaa gcaaaacggt caaatgcttg tctttaaatt gatattgtct gagagaaatc
    17641 gcactaagta cgtcatcgat attaataaat tgattttctt cttttccttt tggcaaataa
    17701 atgtccaatt cgcctttttc gtaattggca gttattttat actccgccca ccaataagtt
    17761 gagaattctt ttttgaaatt atctactgat tctttgcttg ctacgatttt ttctgtttct
    17821 ttctgagcaa gatctgctgt catttttcct gaaaatgctg cggataaaat aagcagtaag
    17881 aaaaaaccga ataaccaaaa gagaagaaac ggtctttttt tcctcatgct ttcctccact
    17941 cctatttaat tttgactatt ctattatata caaaaaatga aatagaaaga caaaaaagtt
    18001 gaaaaagatc gtaaataatt gaacttcttt ttcacaaaat ggtaagaatg gagaatttca
    18061 cgcatttgct ctcaactatt ctttcttaag cctcaaatcc gtttttatct gatacgtctt
    18121 tgaaccaatg acccgatttt ttgattgttc tttttccatc ttgtgctaag tctactgaaa
    18181 taaagccata tcgattctta tatgcattgg tccacgacca gttatccata catgtccaca
    18241 tatgatagcc taaacaattg gcaccttctt gaatggcttg atggacatat ttcagatgag
    18301 attggacaaa ttcgatccga taatcatcgt ggatcatgcc atcttctttg ataaatcgtg
    18361 cttcgttttc tacacccata ccgttttcag aaataaagca gtcgatattt ccataatgat
    18421 ctcgtacatt gatcaaaata tcatagattc cttgttcata gatctcccat ccgcgataag
    18481 gattcatttt acgaccaggc atttcataat tgtcgaaata atcctcaggc attggaccgt
    18541 ttttagtatc gattggtgtt tcttttgctt ttacccggcg tggctggtaa taattgatac
    18601 ctaaaagatc tactgtattt tctttgataa ccgtcaaatc ctctgcatgg atcacaggca
    18661 tgagatcaag ttcttttact atctcaatca attcacttgg aaactcgcct tttacagctg
    18721 gatcaaggaa tgaacgattg aagaacgcat ctgctatttg cgctgcttta acatcttcag
    18781 ggtttgattc gtctcttgga tagcttggtg tcagattcaa gatgatacca ataacaccac
    18841 cttgctccat ttcatggtaa gatttgatgg ctaacgctga agccaacgct tcatgatagc
    18901 caacttggat cgcttttttc atatctgact cttctggata atgccatcga tataaataac
    18961 ctgcttcgac tggaacgatt ggttcattat gagtaaacca tttttttact ttcgaaccaa
    19021 acaattcaaa acaacttttg gcatattttt cataggcttc aaccgtttct cggttcaacc
    19081 atccgccttt ttcttgcaga tacatcggca tatcgaaatg atacagattc acaaagggtt
    19141 cgataccgtt ttcaatcaac tcatcaaaat aacgatgata gaaacgaacg gcttcttcgt
    19201 tgattgttcc agattcatca ggtatcaaac ggctccattg gatagatgtt cgaaatgaat
    19261 tatgcccagt ctgtttcatc aactgtacat cctcttgata cttcgtataa acttgcgagg
    19321 ttttttcagg tcctacttga tcaaagaact tttgcggttc ttttttgtac caataatcaa
    19381 aaatgttctc tccttttcca tcgcctgaaa tccttccttc tgtttgtggg ccacttgctg
    19441 cagaacccca ccaaaaattt gctggaaatt gatatttttt catcaaagca cctctttttc
    19501 ttttttagtt cgttttagtt gattccatgt atgatatttt ccatcacaat cactttttca
    19561 ttttcttcct cttctttttt gattcgtttt aacagctgtt ctgctgctcg ttccccgatt
    19621 ttatctgttg gtggcgtgat cgtgattttc ggaaggatac tcagatcgtt tttatctaaa
    19681 taatcatagt gactgaacgc aatatccttc ccgattctga caccttcttg attgaaacat
    19741 tcgatggcac caatcgacat attgtaattg ctgacaaaaa tagcagttgc ccctttttct
    19801 aataatgctt ttgccccgta atagccgctt tttctagaat agtctcctgt aaagacctct
    19861 aattggatcg atggatcatt ttggaccgct tctttggctc ctgctaaacg ttctcttgct
    19921 acgtagtctg tttgagtggc agcaataaat ccgatttttt tatgtccttg ttcaccatga
    19981 tgagcgatca cttttgctac actttctcga tcattcacta atattgtatc aatacctgct
    20041 ggtccttctg gacaattcaa tgcgataact ggaatactca tttttgtgag catttcaaat
    20101 ccagaccact cttcttcgga taagaagaca atcagcccat cgatcacatg cttcatcagg
    20161 tattcaattt tttgttcaat tttttctggc tgatcggcaa acccgcttaa taataagcta
    20221 tacccatttt cttcagctac tctttcgatc cctgagacaa cttccgaccc aaaacggctg
    20281 gaaatcccgt ttatcaaaag tccaatagag aagcttcgat tattcttcaa ccctttagca
    20341 atgatgtttt ctttatagtc caacgctgaa atcgcttctg ctattttttt catgttcttt
    20401 tccttcagtt gctgaccatt caagtaacgg gaaactgttc ccactgaaac accagccatc
    20461 ttagccacat cacggatcga tgccatacat tctcactcct gccagttaca tttgatttct
    20521 ctttcttgtt gttcgattat gatgaccgca ttctttgcat agtgttgctt gtcatcaata
    20581 tccatataac taaagtcttc agtagagcaa cttcctctca ctattaatta tacttaaaca
    20641 agtatttgaa ccggttcatt tttaatatag cattttttta aaagattgca acactttttt
    20701 aaaacgcttt ctgaaagtgg cggatttttt gcctttttaa aattttattc taaaatttac
    20761 tctatttgtg ggtgttttgt gcgtttttct cttccatccg tttgaagttt tacattccaa
    20821 tggtataatt tctttatcct atcaaatggg ggaagtattt tgaagaaatt aatcgtacta
    20881 tttattttgt ctgcgggact tttgacattg actggctgtg atttgtttgg cggctctgac
    20941 caatcctcgg acgaaacaac cgattcttct gtcttaaaag cggaaaaagc agataccacc
    21001 aacagtgtat atacgctaaa agtacgtaaa gatatggatt tatccgcggg acagttgaca
    21061 tttacagata aaaaaatgga atggacacgc acgtatcaga cacaaggaac tgattcttct
    21121 gaatcatctg aagaaaaaac agtgctgaca gatatcaaga tcactaccaa agatgacgaa
    21181 tatattattt caggaaaaga aaataaaaaa gaaacaacag tcatatttac aaaaatcggt
    21241 aattaccgtt tgaaggatga ggatggcaac atctacagtc tatagtgccg tctgttggat
    21301 cttcttttgt ttctcccctt cttttctgct atagtaaaga agcaagatga ttgtaaagga
    21361 gacgaaatgg atgatcgata gtcctgatta ttgtacatgt aataacaaca aaaatatcca
    21421 tacagaattt aatgaccaag gaagcttgag catatgcgac aactgtcaca aactagtcaa
    21481 agattcattt aaaacatttg aatcttatcc tgttcaaaat tatgtaaaaa gtagaagaag
    21541 ataaacaaat ccaagcaaaa ctcactatgg ctgattttta tgaacttcaa actcagcttc
    21601 ttcctttgat caagcttcat cagtaaaaca aacagtggat catttcagtt tacaaatcaa
    21661 agagtaaaga tttatttatt tcaaatattt gaatataaaa taaccaaacg atagaaaggc
    21721 ttattctaca tcacgtagta attttt
//
LOCUS       DADVXB010000039        21572 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.039, whole genome shotgun sequence.
ACCESSION   DADVXB010000039 DADVXB010000000
VERSION     DADVXB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.039"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            24..671
                     /locus_tag="KB902_001121"
     CDS             24..671
                     /locus_tag="KB902_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6807962.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(744..2135)
                     /locus_tag="KB902_001122"
     CDS             complement(744..2135)
                     /locus_tag="KB902_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807963.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            2392..5781
                     /locus_tag="KB902_001123"
     CDS             2392..5781
                     /locus_tag="KB902_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6807964.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERSDIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            5784..7205
                     /locus_tag="KB902_001124"
     CDS             5784..7205
                     /locus_tag="KB902_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6807965.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            7202..9079
                     /locus_tag="KB902_001125"
     CDS             7202..9079
                     /locus_tag="KB902_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6807966.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            9171..10013
                     /locus_tag="KB902_001126"
     CDS             9171..10013
                     /locus_tag="KB902_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6807967.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(10165..11040)
                     /locus_tag="KB902_001127"
     CDS             complement(10165..11040)
                     /locus_tag="KB902_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6807968.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            11247..12278
                     /locus_tag="KB902_001128"
     CDS             11247..12278
                     /locus_tag="KB902_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6807969.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            12367..12672
                     /locus_tag="KB902_001129"
     CDS             12367..12672
                     /locus_tag="KB902_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBB6807970.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            12851..14866
                     /locus_tag="KB902_001130"
     CDS             12851..14866
                     /locus_tag="KB902_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6807971.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            14868..15152
                     /locus_tag="KB902_001131"
     CDS             14868..15152
                     /locus_tag="KB902_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6807972.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            15178..16551
                     /locus_tag="KB902_001132"
     CDS             15178..16551
                     /locus_tag="KB902_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6807973.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(16634..18649)
                     /locus_tag="KB902_001133"
     CDS             complement(16634..18649)
                     /locus_tag="KB902_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBB6807974.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(18671..19885)
                     /locus_tag="KB902_001134"
     CDS             complement(18671..19885)
                     /locus_tag="KB902_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6807975.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            20106..21050
                     /locus_tag="KB902_001135"
     CDS             20106..21050
                     /locus_tag="KB902_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6807976.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            21195..21308
                     /locus_tag="KB902_001136"
                     /pseudo
     CDS             21195..21308
                     /locus_tag="KB902_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
BASE COUNT         7347 a         3962 c         4050 g         6213 t
ORIGIN      
        1 gaaaaagaag gaatgaatcc ttcatgacaa tgaagggcta tccacgtata atcagagata
       61 aaggagagat gtggatgcca aaagaaactt ttttcaattt atcgaacgca aagaaacaga
      121 gaatcgatga cctattactg gagatatttt gctcacagca catcagccaa gtcaaagtct
      181 cagaaatcgt tgacaagatg gggatgtcgc gcggtgcttt ttataaatat tttcaagatt
      241 tggaagatgc ttatttgtat acgatcaaaa gcagttctca catagtccat caagatatct
      301 taaaattcat tagcgaaaac aaacaacatt tctttttggg gatcgaaaaa tatttagagt
      361 ggtgctgcga cttagatcac gaaagtatct attggcaaag gttatacttg ttaacccagc
      421 gaaatgatca gcagacaacc aaacgtagag aactatcggc tgattctcca atgaacgaaa
      481 aatggctgga attattaaga atcaatcatt tctccattca atcgtcggaa gaagcagtta
      541 gtttcctata cttttccatg accctcgtaa tgaacacttt gacggatctc attgcaaata
      601 attggacaaa agaagagttg ttaaaagact ttcgctataa atctcgttgg attgctgaag
      661 gaatacaata aaaagaaaca gctatgtgta tttgtcctga aatttttatc agggtggttt
      721 atacatagct gttttttgat tattcataac tcgaataagc ggatgagttc ttcttcattt
      781 gcgaatgaca cactatcatc aatcaatata tgaggaacat gggcattcaa aatgggttga
      841 ttcgtaacga tcagatcata ctcgagaaga ttgtatttcg acagctgatc ttcagtaata
      901 gcagttgtct cagagtgaat tttatgcaca gcaagaatat cactgatata ttcttcaata
      961 tattgactat gtcgaagact taagtcgctg ataatcagta tttttttatc agaagtataa
     1021 tggtgaattt caggattacc gataagcatc caaaagatat agctagataa ataataaatc
     1081 agattctgat tcagtagagt ggaataaaat tgaagttctg cacgaaatcc agcatataga
     1141 cgtatctggc ggtgttgcat ctgctgtgca aagtaagttg cacggatcgt caaatgagtc
     1201 gtatcgtatg ggaaaatacg ggagaaaaaa taaatttgcg ttaataattg aacaacatat
     1261 tcttcgtttt tttctttgca atcagcggat gaaaacgaac agtaggacat attttttcgt
     1321 atctgctcac tgatttcatt tttttctttc tccgaaaatt ctgaaaaaat cgtattgaca
     1381 aaatagttca ctacttttat atagctgctg tacttcaatt ttcctaagag atttttcaag
     1441 attaagaagt cttttttatc gatatttatc aactgtacat aagagtctcc agctttccat
     1501 tcaaatggag ttccttggga ttctctcatg agatgcacaa caaaatacat aataaagaaa
     1561 gattgctcat atgggctttc ttcctgaaac aaattcatct gacaattatt cttgaccata
     1621 atttctttga tcttcttttt ttcgattgga aatggcaacg tgcgtcttcc gtagtaactt
     1681 aaaaagaaaa aggtaacaaa gatacgcaac tggagctcac ttttaaggct agttaactga
     1741 aaaccttggt caacgatcac ttttaataaa tagctttcta aaatttgatt gcattgtttc
     1801 aacttacgtg taaaagaaga ccggctgatg gaaatttttt cacaataata ctcaatcgtt
     1861 ttacccggat tgacaataat ctcatttaat aaacgactgt ttgtagaact ttgcgacatt
     1921 tccatcagaa catttaaata agctggtaca ttcaaatgtt caagacgata ccccaatttt
     1981 tgtgaagatt gaatcgttac atccgttccc cagcggattt tgatctcttc gatatacctt
     2041 acaaatgtag attctgaact accaattcgt ttggcaagtt cttttttagt catccacttg
     2101 tcagaaatgg acagaattcg aatgattttt tccatctttc tatagtttca ttccaacaac
     2161 ctgatcatat gtttttctcc ctcaaccctt ttctttcaat gaaacgctca ttaatcgaag
     2221 gaatcaactt cataaatgaa accaattggt atgaaaattg gtgtgattcc ctttagcgcc
     2281 cttcgtataa taattatcat attaaaataa ataaaattat gtaacgcctg tttattttaa
     2341 taattttcac tattcacgtc aaaacagaaa aaaagaaaaa ggaggggaaa aatgacgacc
     2401 acagggaaga aactgaaagt tattttcatg ctgataatat tgagtttatc aaactttgtg
     2461 ccattatctg caatagcaga cactacagat gatccaacag ttttagaaac aatttcagct
     2521 gaagtcattt cggatcagtc tggaaaaaaa gcactgaaca tcaagctaaa tgcgaataac
     2581 accagtgctg aaaagataga aaaagaaatt ggtctagtcg aaaattactt aagtgatgtg
     2641 gaaagaaaag aaggagatgg ctatgcttat caggtaaata gcgggaaaat tacgttggaa
     2701 atctcatcaa acactaaaca aactatcgat ctgagttttc caatcgatcc agcactttac
     2761 cacagccagg caaacaagct gatcgtcgat aataaagaat atgacattat tgatgagaca
     2821 gaaaataaga aagatacaga tgtgtcagta ccaaagccag acgaaataga agaagaatca
     2881 tcaaaagaaa acgaaaattc tgtcagccca tttacattgc ctacattatc cttgccagct
     2941 gtgagtgtgc catctaatca aacgattcct acagaatata caacagatga tcagggcact
     3001 tatcctaaag ccagttggca acctacagga aatacaaatg ttcttgatca tcaaggcaat
     3061 aaaaacggaa caaatcaatg ggatggtata aattcttgga atggagatcc taatgatcgg
     3121 acccattcgt atatcgaata tggaggaacc ggtaatcaag cagactatgc gatacgaaag
     3181 tatgcaaagg aaacaagtac acccggattg tttgatgttt atttgaatgc tcgtggaaat
     3241 gtacaaaaag atatcacgcc tcttgatctc gtattggtcg tagactggtc aggaagtatg
     3301 aacgacaata atcggatcgg tgaagtaaag attggtgtcg atcgttttgt cgatacttta
     3361 gcagatagcg gtatcacaga caaaatcaat atgggatatg tcggctactc aagcgaagga
     3421 tatagctaca gtaacggtgc agtacagatg ggttcatttg attcagtgaa aaatcaagta
     3481 aaatccatta caccttcacg gacaaatggt ggtactttta cacaaaaagc actaagagat
     3541 gcaggaagca tgctatccgt tccaaatgga cataaaaaag tgatcgtttt gctgacggat
     3601 ggtgtaccaa cattttccta taaagtacag cgggtacacg cacaatcaag cagcaattat
     3661 tacggaactc agttttctaa tacgcaagat cggccgggaa atacttctct aatctcaaga
     3721 atctatgatg cacctgacca aaacaatcta tccagaagaa tcgacagtac gtttatcgca
     3781 accatcggag aagcgatggc actcaaagaa cgaggaatcg aaatacatgg tcttggcatc
     3841 caacttcaaa gcgatccggc agctggtctc tcaaaagcag aagtagagtc tcgtatgcga
     3901 caaatggttt catcagatga aaaaggcgat ctttactatg aatcagctga tcatgcaaca
     3961 gatatctctg aatacctagc caaaaaagct gtacagatct cagcaactgt aagcaatgga
     4021 caaataaatg atccaatcgc agaaccattc atttatcagc ctggtacact ttcagtcaag
     4081 agtgtgggga caagtcctac aacggtcact ccatctattt ccatagaagg aaataccatc
     4141 aagagcaatc agatctattt aggaaaagac caagaaatcc aaatccatta ccaagtgaga
     4201 atccaaacag aaaatgagga cttccatcca aatttctggt atcaaatgaa cggcaggaca
     4261 actttccagc caaacattga taccaatgaa ttagctgaat tcggtatacc atctgctaaa
     4321 gctcccggag tcagtcttca catcaaaaag ttatgggaag aatttgacaa caatctagct
     4381 gatcgtccag atcaagttac ttttgagatt caacgggaac atacgacaaa tgctgcagct
     4441 tggaaaaacg gatatattcg aatcattaaa ccagctaaag atacaacaaa tacgtgggaa
     4501 cgttcagaca ttgacaaatt atctgcaaat agcggagaaa gttatcaaga gatattatca
     4561 ctacctcaat acaataatca aggtcaagca ttcagttacc aaacaatcaa agaattacct
     4621 gtaccaggat acgattctca acaaatagat gcaatgacat ggaaaaatac taaacaattc
     4681 acaccgttaa acttgaaaat aacgaaaaat tcctctacag gtgaaaagga tcttattggc
     4741 gctgttttca aattaacagg agattctatt gatactttac taacagatca tggcgacgga
     4801 acctattctc ttccagaaaa tgtcaaattg caaaaagaaa tgacctatac gctgacagaa
     4861 acaaaagctc cagaagggca tggattaagc aaaaagacta cttgggaaat caagatcgct
     4921 tctgatggta cggtaaccat tgatggaaaa acagtcacta cttccgatga tacgatccag
     4981 ttgactattg aaaatccttt tgttgaagtt cctgtagcag tacgtaagta tgcgatgcaa
     5041 gggacggaca aagagataaa tcttaaagga gcagcatttt ccctacagaa aaaagaagca
     5101 aatggtactt atcagccaat tgacagccaa acaacgaatg aaaaaggtct tgccagtttt
     5161 gattcactca cacctggtaa atatcgagtc gttgaaacag ctggtcctgc cggatatgat
     5221 acttcgccgg gaaattatga attccaaatc gataaatatg gaaaaatcat ttacacggga
     5281 aaaaataccg agatgacaaa taatgtatgg acgctcactc atcaaaatcg actaaaagcg
     5341 tttgatctaa cggtacacaa aaaagaagac aacggacaga cattaaaagg agcaaaattc
     5401 agactgcagg gaccagaaat ggacttagaa tcgccaaaag atggacaaga aacagatacc
     5461 tttctattcg aaaatttaaa acctggaact tatacgctga ccgaaacttt tacaccagaa
     5521 ggataccaag gtctaaaaga gccagttact atagttatac acgaagatgg gtcaattcaa
     5581 gtggatggac aagatcatga atctgttctg tcaccaggag ccaaaaacaa ccagatttct
     5641 ttagacatca cgaatcaggc aaaagtacca ttacctgaaa cgggaggaat tggccgttta
     5701 ggaatctatc tagtagggat gattggttgt gcgttttcta tttggtatct ttttttgaaa
     5761 aaagaaagag ggggcagcta aatatgaaaa aacttggttg gcttagtatg tgtctcttct
     5821 tgttactatt taaaccagct tttactcagg tagcaacaga aacagaaaca gaaatggttc
     5881 agattacttt acacaaattg cttttcccaa acgggcaact gccgaaaaat catccaaatg
     5941 acggacaaga aaaagcttta ttacaaacgt atcgaggatt aaatggtgtc acattccaag
     6001 tttatgatgt cacagattct ttttaccatc tacgggaaaa gggcaaaacg gtagaagaag
     6061 cacaagcaga gatcgcaaaa aacggtgcgt cttccggtat gtttaccgca gaagcaacaa
     6121 ctacaactct taacaacgaa gatggtatcg cttctttttc tctggccgct aaagatcaag
     6181 aaaaaagaga taaagcgtat cttttcattg aatccaaagt accagaagtc gtcaaagaaa
     6241 aggcagagaa tatggtagtt gttcttcctg tacatggaca aaacaatcaa aaactttcaa
     6301 ctatccattt gtatcctaaa aatgaagaaa acgactaccc tgatccacct tttgagaagg
     6361 tattagaaga gcctagaaat gattttacga ttggtgaaaa aatcacttat tccttgcata
     6421 cgacaattcc tgtaaatatc cttgactatc aaaagttcga attgtcagat agtgcggatg
     6481 aagcattaac gtttttacct aatagtttaa cgatttcatc gaatggagaa aagctgacag
     6541 aaggctttgt catacacaag aaacctcacg gatttgatgt tttattttcg atcccttcgt
     6601 tggaaaaata tgctggaaaa aaactgacca tttcttatca gatgcagcta agcagtacag
     6661 cacaggcgaa caaggaaatc aacaacaacg gaacactgga ttttggtttt ggtgtcagta
     6721 caaagaaagt ctctgtatat acagggagta agcaatttgt caaaatcgag acaaataaac
     6781 cagataaacg attagctggc gcagtattcc ttattaaaaa caaagcagga aattacctcc
     6841 agcaaacagc caacggatac aagtggacaa agaacgaatc agatgcgctt cacctgattt
     6901 ccgataaaaa tggcgctttt tcaatttccg ggttgaaaac aggaagttat cgattaaaag
     6961 agatcgaagc accttctggt tatattttaa gtgaaacaga aattccgttt accatttcaa
     7021 cttttctttc tgaggataaa gaggcggaca gtatattgaa agtagtcaat aaaaaagaaa
     7081 atagccgtcc atttcttcca aaaacaaacg aaacgaaaaa tacactttta ggcgttgttg
     7141 gtatggtatt cgcaagcttt gcaatctggt tgtttatcaa aaaaagaaca ggagtgaaaa
     7201 aatgaaaaat cataaaaaaa taaacgttat gttaggagtc cttttcctta ttttaccatt
     7261 actcacaaac agcttcggcg caaaaaaagt gtttgcagag gagacagcag ctcaagtcat
     7321 ccttcataaa aagaaaatga ctgatttacc cgatccttta atccaaaaca gcgggaaaga
     7381 aatgagcgaa ttcgatcaat accaaggatt agccgatatt tcattttcag tttataacgt
     7441 cactcaagaa ttttatgcgc aacgagataa aggagcgtcc gtggatgcag caaaacaagc
     7501 agtccagtct ttgactcctg gtacaccagt tgcttcagga acgacagatg ctgatggaaa
     7561 tgtcacttta tctttaccta aaaaacaaaa tgggaaagat gcagtctaca cgatcaaaga
     7621 agaaccaaaa gacggagtgt cagctgccgc aaacatggtt ttagctttcc ctgtatatga
     7681 gatgatcaaa caagcagatg gctcttataa atacgggaca gaagaactag atactatcca
     7741 tctctaccct aaaaatacag tcggtaatga tggaacgttg aaagttacaa aaatcggtac
     7801 tgccgaaaac gaagcactaa atggagcaga atttattatt tctaaagaag aaggaacacc
     7861 aagcgtcaaa aaatacatcc aaagtgtcac agatggattg tacacttgga caactgatca
     7921 aaccaaagcc aaacatttca ttactggtca ttcttatgac atcggcaaca atgactttgc
     7981 cgaggcatct attgaaaaag gccagttgat cgttaatcat ttagaagttg gaaaatataa
     8041 tttagaagaa gtaaaagctc ctgataatgc ggaaatgatt gaaaagcaaa caatcacgcc
     8101 ttttgagatc ctggcaaata gccaaacacc agtagaaaag accatcaaaa atgatacgtc
     8161 taaagttgat aaaacaacac ctcaattgaa tggaaaagat gtcgcaatcg gtgaaaaaat
     8221 tcaatatgag atttctgtca atatcccatt aggtatcgct gataaagaag gaacgcaaaa
     8281 caagtacaca acattcaaac ttatcgatac tcatgacgct gctttaacat ttgataatga
     8341 ttcttcagga acgtatgctt atgccttata tgatggaaat aaagaaatcg acccagtaaa
     8401 ttattctgtc actgagcaaa cagacggatt cacggtttca gttgatccga attatattcc
     8461 ttcattaact cctggcggta cattgaaatt cgtttactat atgcatttga acgaaaaagc
     8521 agatccaacc aaaggatttt ctaaccaagc aaatgtcgat aacgggcata caaatgatca
     8581 aacaccaccg tcagtcgatg tcgttactgg gggcaaacga tttgttaaag tagatggtga
     8641 cgttacatca gaccaaacac ttgctggagc agaattcgtc gttcgtgatc aagatagtga
     8701 cacagcgaaa tatttatcga tcgacccatc cacaaaagcc gtcagctggg tatcggcgaa
     8761 agaatcagca acggttttta caaccacaag taacggttta atcgatgtga caggtctaaa
     8821 atatggcacg tactatctgg aagaaacgaa agcgccagaa aaatatgttc cattaacaaa
     8881 ccgtgtagca tttactatcg atgaacaatc ttatgtaaca gcaggacagt tgatttctcc
     8941 tgaaaaaata ccaaataaac acaaaggtac acttccttca acaggcggta agggaatcta
     9001 tgtgtatatc ggtgcaggag tagtccttct actgattgct ggactgtact ttgctagacg
     9061 caagcacagt cagatttagt ctttttgcaa gaattggaaa aaggagcagc ggattacgca
     9121 aatgctcctt tttcttttat tatcaaacag tcatcacaag gagaacacaa atgaaaccaa
     9181 agaaaaggaa acttctagat ctgctgatgc ttttcttgct tctctcagga atagggatac
     9241 tagcttatcc atttgttagc gacgcgctga ataattatct ggatcagcag atcatctctc
     9301 attatcagca acaagcggtc aaagaaaatg aagaagtcat ggctaaaatc caagaaaaca
     9361 tgacaaagaa aaaccagcaa ttagcaaaag aaggtggaaa tccaggtgca gatcccttta
     9421 ctaagaaaaa agaacctgcg aaaaaggata gaacctattt tgagaaacat acgatcggta
     9481 ttttgacgat ccctgagatc aatgtccatt tgccaatttt tgatgaaacg aatactgtgc
     9541 tgctagaaaa aggtgcctca ttattggaag gaacgtctta tcctacgggg ggagaaaata
     9601 cacatgccgt tatttccagc catcgaggac tgcctcaagc aaagttgttc acagacttac
     9661 cgaaactgac tttaggtgat tctttctata tcgaaatcaa tggacggaca ctcgcttatc
     9721 aagtcgatca gatcaagacg gtagaaccga ctgatacaaa agatctgaga atcgaaaaag
     9781 ggcaggattt cgtgacactc ctaacttgta caccttatat ggtcaacagt catcgcttac
     9841 ttgtcagagg gcaccgggtt ccttatcatg caaaagaagt tcaaaaagaa gtacagaaag
     9901 tatccgagaa caaacgattt ttcctgtatg gattgttagc tgcatgtata ctgattttcc
     9961 tccttcttat atatcttttt cgtcaatcgt tcaaaataag aaacagaagt tagctattcc
    10021 tcatttctat aatatatcta ttcgaatcgt tccgtaaaca aacaggctga ggtttgaaaa
    10081 agaaaacttc agcctgtttt tatgatgata tcaaagagag cctatcaaac actatctttc
    10141 ttattactaa atgaggatct tttcttaagt tttccgatat tctttaagaa ggcctttttg
    10201 catcaattct tgtttgtttt tcaagttgcg gatattctct tcaaaatttt gagaatatat
    10261 cactgagaat aacgtattta atacgtaatc gaaggcaatt tgagaggaga aagtcgctac
    10321 tttagcaaaa tcatattcct cctgcgatat aacaagacac atatcagcct gtttggccat
    10381 ttctgaatgc tgatttccgg taatcagcaa ggtaggggcc tctacatgct tcaaataggt
    10441 cattattcgt tcataatgat ggatgcgacc gctgtagcta ataaaaatgg cgcaatcctc
    10501 gctagtcaaa ttggctgcat tccaagaaga atcactgtat tcttcagcca tgatcaaaaa
    10561 cttattcaac ttgaccattt tattctggaa tttccttgcc gtgatttgag aatcaccttt
    10621 tgcaaaaaga aagattcgct gtgccttgtt caatacttta ccgatttgat ctaaatcttc
    10681 atgttcaatc tgcaattgtg ctttttttat tgactggatc gataaatccg ccattttctt
    10741 tgcaatttgc tgagtgctat cttcacttga aaaaggaaaa ttaggatcaa tcgtttgatt
    10801 gaactgagca atcaattgat gaacttcccg ccccagctcg aaacggaatt ctttaaatcc
    10861 gctgaatccc atttttttgc ataaacgaat gatagctgaa tgggaagtat acgtagcttt
    10921 tgctaattct tcaatcgtca tgtagactgc agcttcgata ttcctacgga tgtaatcgac
    10981 aatccgtttc tctgtcgtgg taaacaactc ttgttttgtt agtttttctt caataagcat
    11041 gatctgacct ccaaattcta tcttactgat aaacacttgg ttccgctact atctttttga
    11101 tttttatcct tactttgaac attaatttca ccaaaccgaa tgataacaag tgtttttctg
    11161 aactttttta ccagaatagc tattataaat actttctgcg cttttctagg atatactgaa
    11221 aacatcaata aaaggaggca ccactcatgc ttacaatcgc ttatcttggc aatggaaaga
    11281 gtacaaatcg ctatcatttg cctttttcaa gaaaacttac gaacaaaatc aatatcaaaa
    11341 aaattttttc cccatctgaa ccagtgtgga aaacattcga agacatcgaa tatactgatc
    11401 agctgtctga tctttgggat gatcctgaga tccaattagt tgtcatcact acacctagtc
    11461 aatttcatta tgaatatgga aaaatggcac tcgaacatgg taagaatgta ctagtagaga
    11521 aaccttttgc agaaacgtca aaggaagcag aagagttatt tgcattagca aaagaaaaag
    11581 gtctatttat ccaatgttac caaaacagac ggttcgattc tgacttcttg acagtccaaa
    11641 aagtaatcga aagcggaaaa ttaggggata ttttagaagt agaaatgcat tatgattatt
    11701 tcagaccgga agtaccagaa aatacgcatg aattttctac tgcgaacagc tatttatatg
    11761 gacatgcttg tcatacagta gatcaagttc tttcttattt cggcgaacca gatgatatca
    11821 gctatgatgt acgtcaactt ttagggaaag gacgaatgaa tgattacttc gatctggatt
    11881 ttttctatgg aaatatgaaa atttcgataa aatccagtta tttccgcatc aaagaacgtc
    11941 caagtttcgt cgtttacgga aaaaaaggga tgttcgtgaa acaaacaaaa gatcgacaag
    12001 aagaacatct gaaaatgttt tacatgcctg atcatgaaga ctttggtatc gatttgcccg
    12061 aacattatgg tgtattgacc tatatagatg aacaagggag ttatcatgaa gaaaaagtaa
    12121 tttccgaggt tggtgattac agccgtgtct acgaagggat ttacgagaca ttagttaatg
    12181 gcgcagaaaa agtcatcaaa gatgaagaaa caatcttaca aatgaaaatt ttggaagaag
    12241 gaatcaaaag cattcaagaa tcagaaggaa aaatatgaca tatttgtaag aatcgggttt
    12301 gttttttgac gcataaactg tcttattgta cgatgaaaaa gtatagaact actaggagga
    12361 accaacatga caaattatga cggtgaaaaa cacaaacgat taagaggttc aatggcccct
    12421 aaaacagaag aagaagtggc tttagcagga actaattctg gtgaaacaga agacaaagaa
    12481 gaatcattag ctggcacaaa ctctggtgaa acagaaaata aagaaacagc tttatctggt
    12541 tcaaattctg tagaagagga aacaaagcct aatgagccca atcactttga aaaagatatc
    12601 gaaaaagcgg ttgaagatgt caaagaaaaa tttgaagaac tgacctcaaa aaataaacat
    12661 gatcatcatt gatcggacga aatcaattca taaaagcagg agacatttgg tcacctgctt
    12721 tttttctgta tccattcgat agaaatcgtt cggtacagtc gtaaaaaaaa tccaactgta
    12781 agttgtacca aacacccctc gatttaaaag cgctaccata ctagaatata agtaggaggt
    12841 gaacagcgct gtgaactaca aaattagtta tctcctgaaa acaccaagag aaatcagtct
    12901 agaaaaagca gcagagatca tcgaagtaaa tacaagcgag gcgatcaaac aattaactcc
    12961 ttttgccgaa tatgtggatg atacccgtat ccgtataaag aaattccgag caatcgactg
    13021 ggcagaaaaa tttttggata ttactcgatt tgaagctgtg tataccgaac aagagcgaag
    13081 agatcttctt tatttgatgg tttattcgac tgcaacgtct gtttctgttt ttcattttca
    13141 agattttctt caggtttcta aagggacagt cctgtcagat atcaaaaaga taagaaatga
    13201 attagaagtg gaagattgtc agctgtcgta tactaggaaa actggtttta ggctgctagg
    13261 gtcagaagca atattaagaa gagaagcaaa aaatcgcact gctcgtttga tgcagtcact
    13321 tgctggaaga tttgggctca cgtatttaac cgcaaccctt tccattgatt attacgccaa
    13381 agttagagat ttgctagata aaacgatttc actatcagat cttcgattcg caccaaatcg
    13441 aatggatgaa ttagcttatt atttgagttt gacaaccatt cgaattggaa aaacatccat
    13501 ggaactggta aaagatgctg aactgttggc ttctcttgca gtcactgaca ttagtcgaca
    13561 agtattgact ggccttggct attccgaaca tcaaaattcg gagattatat ttttctctct
    13621 ttgcttagca tcgatcgttg aaggagatgt ccaggagcct gcacttgatt ttttgctgga
    13681 atgttcttca gaagtcatcc atcgcatgga attcctgatg gccgtagaat ttgcttcgtt
    13741 tcgtgaatta ttgatgaatg tcttttatca cttggtccct gcctattttc gtatttccta
    13801 ttctttttat ttacctaatg tgatgatcga tcaaattaag catcaatatg cttccatcta
    13861 cgaaatgaca agaaaagcat tacttccgtt agaaagacga atagggaaga gcatccctga
    13921 agaagagatt ggttttttca ctatactatt tggcggagag atcagaaaag cggacgcaga
    13981 agaaagaaat agaaaaataa gagccgtgat cgtctgtcca agtggcatta gctcttcatt
    14041 gatcttaaaa agtgaacttc agcaattatt cccgatgatc ttttttacag agactaattc
    14101 agctgaccgc ttacacgagg ttgacgaaac ttcttacgat attatttttt ctactgtacc
    14161 tctcacactt actgataaga aaaagtctct ctatgttctg catccaatca tgactgactt
    14221 ggaaaaaaat cagctgatca atcaagtaca aagagattgg ctgataccag gattttcaat
    14281 gccttctgcc caagaattgt tgtcggcgct actgccttat atcgaattaa aagaaggcgt
    14341 agacgaagaa aagctctatc aagtattaaa tcgtaaaatg aacaaacttt tagaaaagaa
    14401 ggaggatcaa cgtcctatgc tatctgaatt attaacagaa gaaatgatcc aattatcgga
    14461 tcaaccaaaa aactggcaag aagcaatcac atttgccgca cagccgctat tatcagaaaa
    14521 taaaatagaa gaaagttata tcaaagctat gatcgagcgc gtggagcagt atggtgcgtt
    14581 tatccatatt ggcgatcaca tcgcattacc tcatgctcgt ccagaagatg gcgtaaacga
    14641 agtagggatg tctttgctga aacttcaaca acctgtggat ctgcttgata atccagccca
    14701 tcccattagt ttgttcatct gtttagctgc tatcgataat gaggcacatc ttcgggcttt
    14761 ggcaaattta acaaagctac tttctaataa acaaaatctt caagatttat tacacgcatc
    14821 aacaaaagaa gaaatattag cgatcataag aaaaggagac gaatgatatg aaaatttttg
    14881 cagtatgtca aagtggatta ggaacaagtt ttatggtaga gatgaacatc aaacaagcac
    14941 ttgcagatct tggagcagat gtggacgagt ttgaagtaag tcatacggat gttggaagtg
    15001 tatctagcga tatggctgat tatttcttca ttgagcattc tttgaaagat acgctaactt
    15061 ctatacctga tgaaaagctc gtacctttgc aatcgatcat tgacagcgaa gaagtaaaag
    15121 aaaaagtaac gaagatcttg tcaaaagaat aaaaatgatt caagggagga actatcaatg
    15181 gataaattgt tgaatttgtt tgtgtcaatc gtcagtcagc cctccatcct cgtttctttg
    15241 attgcactgc ttggtctcgt tcttcagaag aagaaatttt cagaagtgat ccaaggaact
    15301 atcaaaacat ttgtcggatt cctagtactg atcggcggtg ctggtttaat cagtaattca
    15361 ctaacccctt ttgcttcgat gttccaaaca gctctgcata ctcaaggagt agttcctagc
    15421 aatgaagcag tagtggcgat tgctttgcaa caatacggta cacctactgc tttgatcatg
    15481 ctagtaggga tgatcgtgaa tattttactt gctagattca caagatataa attcattttt
    15541 cttacaggtc aagcaatgct ttatgtttct tgtctaacag cagtcatttt agtaagcgcg
    15601 gggtttactg caaatttgtg gatgatctta ttaggcgggg tcttcgaagg aacactatta
    15661 actattacgc ctgctctttg tcaaccgttt atgaagaaca tcactggaaa caatcaagtt
    15721 gcgttagggc ataccggaaa tatcggttat gcttctagtg gatggatcgg aaagtttttt
    15781 ggaaacaaag accgttctac agaggacata aagattccta aaagtttcag ctttttgcga
    15841 gattctactg tatcgatcat gctcttgatg tcgatcgtat atgtcgcact tgctttgtta
    15901 gctggtcctg gatttgttga aagagaacta agcaatggag acaacgctgt aatctttgca
    15961 ctgatccaag ctggaacatt cacagctggg tttgttatcg tccttcaagg ggttcgaatg
    16021 gtgttggcag aaatcgttcc agcattccaa gggattgcta aaaaactcgt acccgattct
    16081 aaaccagcat tagatgttcc tatcgttttt ccatatgcac ctaatgctgt attaattggc
    16141 ttttttgtta gcttctttgt aggaacacta tccatgtttg ctatgatagg cttgcaaact
    16201 acagttatca ttcctggggt agtaggacat ttcttctgcg gagctgcttc tggtgtcttc
    16261 ggcaactcga ctggcggtag aagaggggcg gtattaggtt ctgctttcaa tagcttattg
    16321 attagttggc tgccattatt tatccttcca gtattaggag atcttaaaat cgcttcttct
    16381 acatttgccg atactgatta tctagtacca ggacttgtac ttgggaaact aggagaatac
    16441 ggtcaaatag ccttgacagt tggaatcatc gctttctttt tacttgtcgt attatctagc
    16501 tttctttttg ccggaaaaag aacaaacatt gtttctaaag aacagaatta agcaaacttc
    16561 aaaataaaaa ttgcttggac aatatcagaa gaagatttaa agtcttctga tatgtcgcaa
    16621 gcagtttttt gttttatgca tttatttttg aatagcttgt taagacaagt ggctgttttg
    16681 ctagaagagg ataactttta ccattcattt tcactgttcc gcctgttcta tcagaagtaa
    16741 tcacgatctt atcttttgtt ttttcaagcg aaatctttcc atctttgata ggtagcgtac
    16801 aattcagtgt ttcaaatgaa tctagattag gttgtatcat aaattcttca taacctggct
    16861 ttgttggata caaaccgata aaatagcgtc ctaaaagata gattgggctt gctccccatg
    16921 catggcataa gctttttcca taaggatctc catacatact gtacttttca tttcctgttt
    16981 gagtagggtc gtattcttcc cagaaagtta ccgcatcatg agataacatc cctccccaat
    17041 aatcaagaat cgtttggtag acgatattcg tctgtccgag tttgcataaa gcatcttgtt
    17101 catagaattt gaaatatgga gtagtaatct gtgtgatagt gtcattcaat aagacattct
    17161 ttaagatcga ttgctgttgg tctttgttag caaaatcgaa taaaacagcg aaaatattcg
    17221 catgacgcgt cacatttctt ctcccagatt catagcaatc gataaaagcg ccaagttctt
    17281 catcccaaaa gtagtcaaat aggttttgtt tcaatagttg atatttttct tgatagagat
    17341 gagtatgata attttcgttc tctccatatg tttcagctaa gatatctccg caagtgatca
    17401 tggaatgata ggctttcagt aataagactt gttctgcagc aagcgttcct tctttatcca
    17461 tttcagacca atcaataaat atccaatctt ttgctctccc ataaataaac cctaattcat
    17521 tcgtttgctc catcaagtat ctcattaatg attgcatctt agggtagacg atgcgtaaaa
    17581 attcatagtc tttcgtcatc atatagtggt tttcgatacc aatcaaccac aagatcgaat
    17641 agtcaacgat agtattcata tgctgcttga tttcattttg tcctcttaat gctaatatcg
    17701 ttcgtttatt gatttcctcg tcaaaaaaaa gatattgatt gatcatgaat gattgatacg
    17761 catctccaga ccaaatccag cgatctcgtt tgataccgtc gataaaaaac aaatcactac
    17821 ataacttgaa ggcttcttct gatactgacc agatctgatt cagtaaagaa gaatcgcttg
    17881 aaaaagcagc ttgtttcgaa agagataaaa attcatgaaa aacttgaagt tgaaccattc
    17941 cagtagaaac ctctggtata aacaaatagc gaaaagcgcg tttacgagct ttcatttttc
    18001 ttgtcattcc tatttgctta tagtagcaat aatcgatatc catagcttct acatcggact
    18061 ctccataaca tagagtgata gattcgatat ggtcatccag agatattagt tctacacagc
    18121 cattcactgc tcgcccaaaa tcgaataaga ttcctccgcc aatctccgtt tcagtgactg
    18181 gatggacgca ttctttttga taatagattt gatttggatc ttttgcgata tcgacataaa
    18241 gcggactcca gccagctgga tattcttcaa taaaattact tgctgtccag ccaatatctg
    18301 attttacttc gtctccctcg ataaacatcg ctggtagccc tgatgtatgt cctacaaaga
    18361 tacgaatttt tgctttacca gctggacaag tcagccattt tccacatgga tgtttttgtc
    18421 cattaatttc tacataccca actccttgga tcgtcacttt aaacatggaa ggttgatcaa
    18481 gaaagtaata tctcttaaac ttgacgttcc gatggcaatc atccatgtac cagtacgctg
    18541 gccagtcaaa acctcgttct tcccgttgga aattttgtag cagtccatgg cggatctcaa
    18601 agtctccagg ataccaaagc catctatctt tatgtttttc atttgtcatt ttacacgacc
    18661 tccatcaaat ttattttgtt gtcaattgtt cttttatttc ttcatctact cttatcactg
    18721 tctttctatt cgtcctgtgt actactagaa ggctaataag cgcgctaatc aacagcaaga
    18781 tactgccatt gacgaaaaca gcaagtgttt tactcccaag agaagcaaaa gagagaaaga
    18841 gcaaaccata tggtgcaatg aaagtaccta aattagcgcc aaccaataag attgaagtat
    18901 tgaaactctc cgcgtacttg ggcgcttgga tacttacttg gttgaataag taaggaatga
    18961 ataacgaaaa agaaattcct gttaggatcg caccaaaccc aatcacatac aggtttatca
    19021 cagtggcaat caatacaaag ccgattccca tcagtagtaa agaaagtgta agcatatagc
    19081 gatgtgcttt tgtctgaagc cagccaaaac aaactccggc agccatactt gccaattgca
    19141 tgattgttaa gatattcgct gcattagttt cgtttcctag agaataagtc gtcaggactg
    19201 tggctaattt aatcgataca gcattatata ccacgatgac cagcaagaga aaaataccat
    19261 aactaatcat tttaggattc gttttgatta cttgtcttgt tggggctgtg ccatgcgatt
    19321 gaagttcagt tgtttcaggt gtaggaacaa acaaaacaaa caagacaaga ataggtaagc
    19381 tgatggcgta gactaaaaag gtatattgcc aaccgaactg tactagctgt cctgcaacaa
    19441 atgtcattaa agctgcacca aatccttgaa atgcactttg aaaaccaatc atagaggctc
    19501 gttcatctcc gtgataaaag gcagcaatca tgctgactgc caaagaattg atcaatccaa
    19561 agccaatacc tagtccagct cttgaagcta agacaatact gtaactttgt gagaagaggg
    19621 ggaggatacc acaaatcgat gcaatcacta atccgatgat cacagtttgt ttttgtccga
    19681 ttttcctagc aataaaacta ctaatcaaaa caaaaatagt gaccataaaa gagggagcag
    19741 tcgttaataa ttcaacagca gataaagaac gcgtggcata agtagctgac atactgggaa
    19801 ttgcagacgt gactgcacca gcagaagtca aaataagaga gactgacagc agagaaaatt
    19861 tcatcatctt tttattcata agcatgttcc tttcattttt gtaagcgctt atcaaaaata
    19921 tagtatgaag tggttattct ctcaatagcg gaatcacagg aagttcatgt cccaaccata
    19981 gaaagtcttt atgaaaccaa aaatagcttt gcatataata gcagtacagc gtgaactaat
    20041 aagcgaaaga aaccgcttac aaaaaggagg gagtcaattg gaactagctg aattagacat
    20101 tttttttgcg taacgaagaa tcaatcgaaa ctctgcagcg tgaacaagga atgaatatca
    20161 atgatttaaa cttagcttac catcttcaga caccgccaaa aatccaccga ggggatctat
    20221 ttcaacaggg aaatattcat atcagtaaac accgtcgata tgcggaagtt cccgagcata
    20281 cacatgattt tgttgaaatc aattatatgt atagcggtac atgtttacaa attattaatg
    20341 gagaaaggat agagatggaa gaaagtgacg tggtgatcat tgataaagaa gctactcaaa
    20401 gaatcgaata cacagggcaa gaggatattt taatcaacat cttattaaaa gaagaaacct
    20461 tatctacaga gatattgaat catttggcaa gcacaaataa tctactttct tcttttttga
    20521 taaatgcatc aaaagaaaaa ggggaacata cacaattcat tcattttcgc ggcggaaaaa
    20581 caagtcgttt gacgcatttg attgaaaata tgctgttgat ttattttgat acatacagtc
    20641 ataagatccg ttcgttaaat ctctatacat cactattact gatcgaattg actcatttat
    20701 tagaacaaca aagcttttca tcagcagatg gatgcgcaga aaatgagatg cttagagtat
    20761 tagattatat cgataagcat tttacttctt gtacgttaaa agaaacagca gctcattttg
    20821 gctacaatcc ggtctatctt agtaataaat tgaaaatgta ttttgatgct tcctttcaag
    20881 aactggttct aaagaaaaaa ttcgactttg cgttggaact gattcaagaa acgagttttt
    20941 cgttggaaga aatcgctaat cgtatcggat ataaacaaac gacttcttta ttcaaattat
    21001 tcaagaagta ttcaacatgt actcccaatg aatggagaaa taaacattaa gaagaaaatc
    21061 tttcactaaa gcatatgaag gaaaattgtt ttaggtgcga ttgctgtctt attatatcgt
    21121 tgcagcgaat ttttttggat ttattttcag ttctaaactt ttggttgtat tatcagggga
    21181 tataggtgta aaccgttgac gaaaatggtg ttcgtgaagt tgttgaatta tcaatcaacg
    21241 aagaagaaaa agcaatgttc agcaaatcaa caagtgcttt aagagaagta ttgaacactg
    21301 tattataaga aacaatgaat atgaactaaa aatcctaaaa ctgcttaaca gctgaaatag
    21361 ctgttaagca gttttttatt gatatctaat aggtaagcaa ataaacagaa tggttaaaat
    21421 taatcggtcc gaaaatgtat ccgtacatat gaacatatga aatttaatct gttgattaca
    21481 ataagcgaat cgttatcaat gtttatctgt ggttaattaa aaaatccttc cgcaacggca
    21541 aatacaatga ttcatatcta attcgttcat at
//
LOCUS       DADVXB010000040        20870 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.040, whole genome shotgun sequence.
ACCESSION   DADVXB010000040 DADVXB010000000
VERSION     DADVXB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.040"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            32..355
                     /locus_tag="KB902_001137"
     CDS             32..355
                     /locus_tag="KB902_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807977.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            773..4402
                     /locus_tag="KB902_001138"
     CDS             773..4402
                     /locus_tag="KB902_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807978.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            4462..4824
                     /locus_tag="KB902_001139"
     CDS             4462..4824
                     /locus_tag="KB902_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807979.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            4838..4990
                     /locus_tag="KB902_001140"
     CDS             4838..4990
                     /locus_tag="KB902_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807980.1"
                     /translation="MLDQNTDRSWWMIGAVIVGAILIGTAKVAFPEVFNIVITFFKNM
                     IPTNLG"
     gene            5058..5480
                     /locus_tag="KB902_001141"
     CDS             5058..5480
                     /locus_tag="KB902_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807981.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            5492..6907
                     /gene="tadA"
                     /locus_tag="KB902_001142"
     CDS             5492..6907
                     /gene="tadA"
                     /locus_tag="KB902_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6807982.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            6924..7739
                     /locus_tag="KB902_001143"
     CDS             6924..7739
                     /locus_tag="KB902_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807983.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            7739..8536
                     /locus_tag="KB902_001144"
     CDS             7739..8536
                     /locus_tag="KB902_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807984.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            8554..8916
                     /locus_tag="KB902_001145"
     CDS             8554..8916
                     /locus_tag="KB902_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HBB6807985.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            9088..9309
                     /locus_tag="KB902_001146"
     CDS             9088..9309
                     /locus_tag="KB902_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807986.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            9328..9603
                     /locus_tag="KB902_001147"
     CDS             9328..9603
                     /locus_tag="KB902_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBB6807987.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            9712..11538
                     /locus_tag="KB902_001148"
     CDS             9712..11538
                     /locus_tag="KB902_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807988.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            11551..12267
                     /locus_tag="KB902_001149"
     CDS             11551..12267
                     /locus_tag="KB902_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807989.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            12280..15138
                     /locus_tag="KB902_001150"
     CDS             12280..15138
                     /locus_tag="KB902_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6807990.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMSTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTGKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIQFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILKNKIIKLKNAMTKLAKAI"
     gene            15189..17825
                     /locus_tag="KB902_001151"
     CDS             15189..17825
                     /locus_tag="KB902_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807991.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTMISSGIQ
                     FAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNALKEKNF
                     FSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFSDSFKG
                     GYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIETGQRS
                     KVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVFVLIKG
                     SGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDSGEGED
                     RKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDMAND
                     TKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSNRKDGAKVENADR
                     IMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQE
                     AKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGLEKLVKENLQNS
                     TSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGVRENLQSSSTSQ
                     PKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGFKTVD
                     VRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFT
                     YEDNELFRDTLNDPNPLFDNLN"
     gene            17849..18184
                     /locus_tag="KB902_001152"
     CDS             17849..18184
                     /locus_tag="KB902_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807992.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLMPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            18181..18798
                     /locus_tag="KB902_001153"
     CDS             18181..18798
                     /locus_tag="KB902_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807993.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            18814..19281
                     /locus_tag="KB902_001154"
     CDS             18814..19281
                     /locus_tag="KB902_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807994.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            19297..>20870
                     /locus_tag="KB902_001155"
     CDS             19297..>20870
                     /locus_tag="KB902_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HBB6807995.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDEC"
BASE COUNT         7907 a         2687 c         4100 g         6176 t
ORIGIN      
        1 tttagtaaaa aaattaaagg agtgatagct gttggcaaga tcaagaattg ctaaaattga
       61 acagactaaa aaggataaaa aaatttctaa aaataaaaca aaattcttta aagctgaaga
      121 tgttaagagg atagcatggt ctgtgaaaac atttgatgaa gatcgttatg ttaaagtttc
      181 aatgaatggt ctatttgtac agcttggtaa cttcagtaat tttaaaacga ttgatgaact
      241 ttatccggaa ataagaaata ttgtggatag taaaggttta atcgtggcta aacggaaatc
      301 aagaaactct ggtcttgctt actgtaaaaa taaagggatc atgattccgg cttaaatcag
      361 tgaaattgtt ctttgaaaac ttaatactac tcgtactgta gcaatgttgc tatgttacag
      421 ataaaagcgt aaggctaata agcaaaatag caaccaagca tactgttatt tcctttgcca
      481 agaggtatgt aaatacgtta gcaatagaag tgataaggtt agtatttcac gccaaaaaat
      541 acaaaagtcg atccattgaa actactaatt atgaggtggc gtaaatggta attattcaga
      601 atttctatct aggaagaacc tatgaaaacc gtcctagaga tcagaatatt gacactaaaa
      661 aattcagcac agtaataaat gtgctagata cagggtaact ctttactaca agaaatgtag
      721 taaagagttg ttatgattct ttattacatt tctttctaaa ggaagtgtga taatgaaaaa
      781 actaaaactg attagcattg ctctattcag cctaatcact atgtcaacgg ctcgccaatc
      841 aattgtttcg gctgaaggaa cgtctacgaa agcagtagta gaagagtctg gcgataaaaa
      901 agttgctata gacgacaaag tgaaaaacga agcggaaaaa gcgactgtgg ttcaaggggc
      961 agacggcttg atgtatgtgg tcgttgatga aaatgatcct gaaaaattgc tagaagctga
     1021 atctcctttg aaaaatcaac aagaaaatac cggcgctgtt gaagtcggtg ttgatgaaaa
     1081 gagacaagaa aaggctgata aagctaacga aaaagtgaaa aactttgacg atattgatta
     1141 caacgatatt agttcgttgc agtcagcgtt gaatgatccg aaattccctt ttttatcgga
     1201 agatgaatta aatgaaaaat tgcaaaagac aaagaataca tttgagtctg aagcgctaat
     1261 gaaaaagaca aggggatatt tcagtcaaag gattttagag ttaagcaata atttaaatga
     1321 cgtaccgaaa agagcgaaag tgagtcggca tgctttagtt agtaaccgtg cttcacaagt
     1381 aagtgaaaca cgaataaacc ctccaaatgg ttatccgtgg gtgatttatt taattaggag
     1441 caatggttat agttatacag aaaattatgc tattagaaga actattgatg ggaaagaagc
     1501 tttttgttta caggccggtg tacaagcgac gaatacatac actggttcaa caagtggtta
     1561 tctttctaat tcgcaaagag aaatgattag ttcgatttta tcagcatata aagaattagg
     1621 cggttgggct aataatgatg ccggaaaaca aagatggata gcaactcaaa tgcttgtttg
     1681 ggaaaacagt aatgaaaagc ctaaaagtat aactgttacg ccaaattgga aaaacggagc
     1741 tactaagtgg aaaaatgatt tagtggctcg tgcaaatgct attagagtaa gaacaaaatg
     1801 ggattctacg tctaagacgg ttgatgaggg agataaagca acctttaaag taactaatac
     1861 ttatggagat cataatttgc atgtgaaatc tgtatctggt ggcggcaaag ctaccataag
     1921 caatggtact ttaactgttg atactacagg agccactgga aacaaaatca ctgtagatat
     1981 gattaaaggt tctcaccctt cagacgcgca ccctacaacg gtatggagta atggttctta
     2041 tcaaaagctt gttaccggtt ctttttacat tagtacttct gttacggtaa atgttaagag
     2101 aaaaggaact gttgaagttt taaaagttga ttcagaaaca aaaaaaccat tatcaggagc
     2161 aacatttaga tttagctact caggtaaaac aaaagatgtt actactgatt cgaatggtaa
     2221 agcaaaatta actgaaaggt tgaaagctgg aactgtagta aaagttaagg agataaaagc
     2281 tcctaatggc taccaactag attcaagcga attttcaatt acagttaaag aaaatcaaaa
     2341 tgttactacc acaagaacca ataagaaatc cacaggttct gtagaaattg aaaagatagg
     2401 cgatttagat ggattaggac taccgaatgt agtattcacg atttataatt ccgataacaa
     2461 agttgtaaaa gataacttaa aaacagatag taatgggaaa ataaaagtcg atgaactgca
     2521 atttggtaaa tattatgcag tagaaaaaca aggtgttact ggttatgatc ccgatggtaa
     2581 aaaatacaat tttgaaataa gtcaagatac tccttttaca aaaccggcta aagtgaaagt
     2641 aacaaatatt tatgaagtat ccataagcga aaaagtatcg gacatgaatg aaagtcaggt
     2701 attaaaaaat aattggtctg ctgatccaaa cgattatctt caatatgaca ttacaactgg
     2761 aaatctaaaa aaatcgggag aaagaaacgt ccaaagtttc attatcgaag ggttttacga
     2821 caataagaat gtagatgtgt caaaaagtga agtatatgtt ggatcaacaa atgtaacaaa
     2881 ctcttttgac attaataacg atactaacaa tggaaaagta attgctaagg cgaagacaag
     2941 cgtattaacg aataatgatt tttataataa gtcctataat ttacggatca ctatgaaaat
     3001 taaaaaatct actcttgaaa acactgaaaa gcaaaaaaat ttaacgattg ttaaaaatag
     3061 taaagttact gtcggttcaa aaatctctaa atctgctagc tctaatgatg tagaaaccgt
     3121 tttatattca agaaaagtta ctatcaatca tattgatgaa aaagacaaac accttttgaa
     3181 acaagatatt gattataaat acgatgggga aacgtatgaa tataaaccta gaaccgattt
     3241 atttgataaa gatggaaaca attataaatc tgatgtaatc cataaaggga aaattgatgg
     3301 aaaagatata gttttaaaca ctccctatca tattccggta ctttctgtga atgtggatcg
     3361 gattcaaatt gatacggcta gagctgttaa aaatggctat ttacctacaa aaatagaact
     3421 aagtaaaaaa gaagaatatg aaaaagaatt agaaaaaatt gtattcaaag ttaaaattac
     3481 agatatagat aacaataaag ttgtttatga tgaaaacttt aaatacaaag aatttaatag
     3541 tcatatgtcg cttgatttac ctacagaata tttaacaaag aataaaaaaa tcaattatag
     3601 tgttgatatt cttttagtgg ataatccaga taaaaacaag ttcgaaactg aaactaaaga
     3661 tttaagaacg atcggttata cttcttctga aaaagtttta acaaacaaag atatgacaaa
     3721 taaccaagtc aactattcag cagtagttag aacagtgaaa gaaagagaga ataataatcc
     3781 ggtcaaagag ttcaatgaga gtatcaatta taaatttact gatagcacta aaacaaaaac
     3841 aggatatggt atatcagttg atttagagcc aacatataga aatgaaattg ggaaacaaat
     3901 agatatgaaa gtctatagtt atccgatgaa tgaattgatt gacagcaaaa ttgacgaaat
     3961 ctatcaaagt gggggaaaag aaacagaagt taagatggat cgcttaaaga atgatggtaa
     4021 agttgagtcg ggtattagta ctcaaaatct ttcattccaa tttccacata tgaatatcga
     4081 aagaaaaact ggaaatatat atgctgacag tcaaagaaat gatgaatcta ttaagtatga
     4141 attgatcgat ggcggtagaa aattatatgt gcctatttgg tgtgatttgg gaaattattc
     4201 tattgctatc aaaagtagta actttggtgg taactatatc tcgttggata tgaaccagaa
     4261 catagatgtt tatgcttata tgtatgcaac gatagatagt gaaacaaaaa aagatgatga
     4321 attactgctt gaacctgttt atccagagtc tactctacca gatggttgga gcaaaaatga
     4381 gattgattgg ctgaataaat aagtttgaaa agtttttatc tatctgatag aattaaataa
     4441 tgatataggg atggtgatag aatgagggtt caaagctatg gtaacagtgt ctttgatgtt
     4501 aaaagagaat ttcaagattc tagaagaaaa accaaaaagc tgatagctta cttcattcta
     4561 tcagctatcg ttttctatat tgtcaagttt gttttggaat taaactcaat agtattcaca
     4621 gatatggttc ataaaatgtt aaatggagaa cctattaatt tcaactttga ttacatgctt
     4681 gaaaaagcac aaagcaatca aattgtggct tttatcgtga gtatctatta ttttattgaa
     4741 aaatctattt tttctttaaa agattttttc tttgaaatgc ttaccaaact aacaacgttt
     4801 tacaataaaa tttcaaaaaa ttaaggagga agtttgaatg ttagatcaaa atacagacag
     4861 aagttggtgg atgattggtg ccgtgatcgt aggtgccatc ttaatcggga cagctaaagt
     4921 agcttttccc gaagtgttta atatcgtcat tacatttttc aaaaacatga tccctacaaa
     4981 cttaggatag ttccactaaa aaattcacgt agtttgatgc gtagaaaaat aataaagaat
     5041 gaaaaaggct acataaagtg atttatgtag cctttttttt ggatggaagt gatgtaatgc
     5101 taagagatat gcccaaaatg attcttttaa tgtttgttgg gttcttttta attttagtga
     5161 ttgcgtacta ttcattaaat ggctatacac aagattcgtc tgtgaaaggt atgcaagaaa
     5221 cgttaagaac tacagcaata gcaaacaggg atgatagtat tcgagtagaa aaaggacgat
     5281 ttgctttaat taagtctgat tttgaaaaag attttaaaga aaaatttggg aaaagtaaaa
     5341 atctaaataa tgaaaccgct gattataaat ttgattatct tacagatggg aaggacggta
     5401 ttaaagcaat taaagtgaag gttgaaagtg gatcaaaaga atatcaagca acttgtattt
     5461 taaatgttgc aaatgattag aggtgtgaaa tttgcgtgtt gtagaggaaa agaagatttc
     5521 tccaaaaatc gaggaaactc ctaaaagtaa aattaatatc gcaagtatta ttaaaaaaaa
     5581 tggaattaaa gaaaactctg aagcgataga aggaaacctt gattttttaa ctaagctttt
     5641 agaagaagat agtggaaatt atgaaccacc aattgaagat gcaaaattaa atatgattcg
     5701 tgatgattta accagaaact attcccaaga agttttacaa gctttaactg atgatgaaat
     5761 taggcgaaaa cttgtacaag ttgttttgaa agaacatggt actttcttta aaaaagataa
     5821 agaggttgca gaatatgtag tacgtgaatg tattggaaca gggattattg agcgaattat
     5881 gaccaacgat gaaattacag atgttggttg gaatggctct caacttagca ttgaaactaa
     5941 ctctaacaaa tggttgtttg acggtgataa attaaatatc acgcaagagt atattgaacg
     6001 tgttatttct aaatatgctg ttgtaaatga tcgggctttt aatagtggta atcctatcat
     6061 ggatggaatg tttaaaaatg ttcgtatatc agctacacac atagataatt caccagatgg
     6121 ctctacgttt tctatgcgtg tggcaaggcc tagattagca ttgaataaag aaaactttga
     6181 agattttgct cctgattata ttttggagct atttgagaaa atgatgaaaa caaaagcaaa
     6241 tatctgtata tcaggggaga caggtacagg taaaacggaa cttcaaaaat tactgctaag
     6301 ttttattgat aatcatgatc gtatgattat gattgaggac gttcaagaaa ctcacgctaa
     6361 agaattattt ccggataaag atattttctc ttggatcact actcccaaaa aagcaatttc
     6421 agatttagta aaagcttctc ttagaaataa tccacgatgg atcattgttt cagaaacacg
     6481 tggttctgaa gcttatgaaa tgcttcaagc ggttttgtca ggtcactatg ttgtaacgac
     6541 acttcatgcg gttaatgcac gtgcgatacc tagacgtttt gtaaatatgt gtgcaagtgg
     6601 ttttaaaata aacgaaaatg cggttgagga agacataaat cgttatttcg attttggtgt
     6661 ccatatcaaa aaaacagtgg ttgatggtaa agtgatccgt tatttgaatg aaattgttga
     6721 attttctgct agtgaaccga ctacagtttt taagcaaaaa tttatcaatg gaaagtttgt
     6781 cattgaaaat ggtagtcttt ccgaagattt taaagaaaaa atggctgaaa aatttattac
     6841 gtttgaattt cctgaagatc aaactaatac agaagaatca cttcctgaag aagaagaggt
     6901 gatttaagtt gaaagtacag gctatgacaa agcgaaaagg tctcatggat gtttcggaac
     6961 taaacgccta tcaagtagcg tatggtaaac cgttagatta tagagattat ttgaactatg
     7021 ttggattacc ttgtttgttt atgggtggct tttcttttgc tttatgttac tactggtgga
     7081 ttgctttgat ttgtggagta attggaggcg tatatggctt taaagttata atgcctaaaa
     7141 gtattaaacg ctcttatgaa ttaaagagtt tacaggaaag aaataaattt attaacaaca
     7201 tgactcaaat tttgaccgat gatagtaaaa cagttactag agcgttatct atagcaaaac
     7261 agcgaacaaa aggtgaatta agagaagata ttcaaatctt agaatcacgt ttacaaggtg
     7321 ctgataaatt tcagattgct gaagcttttc gtgaaatcaa caataaatat tatagtgatg
     7381 ttgtttttac acaatacttt gagcaattgg aaacagctat ttacgaaggt agaaataatt
     7441 cagatactat gaagcaaata aagagctatc ataatgatgt gaaacgtaaa acagaaggtt
     7501 ttatgaaaat caaagacggc tatcttcaag atatgaagca aatgatgttt attgtagctg
     7561 tttttattgg agctataact tttgcttttg gtttttctac tttctatgaa ggttttgctc
     7621 gatcacctat cggatgggta tttggatcta tttacttttt gattatggtt agcttcatga
     7681 agtcattttt caaacattat tttgatgatg aaataatgag tttgggggta agtaattaat
     7741 gaaagttaag gctttaaaaa agaaaagaaa atcaagtatt agccccttga aaattacgaa
     7801 aacagaacat aaaagctttt ggattaaatt actaggtgat gtttattatc aaaaattacg
     7861 tgaaatgaac aattccaata ttgcgattat taagtggcaa aaacaacggt taaaaaagtc
     7921 attgattttt atcctagtcg gattcttaat gtatctattt ttagggaaag aatggtatta
     7981 cttagccggt ggaattgcta cttcagtagg tttttatgtt tggcaagcaa aatcaatcaa
     8041 tggtatctat aatcaatttc ggtttgaacg acacttgcaa tttagtaaat ttacacggct
     8101 attgatcccc tatctgaaac aaaaaaaaga tggcggaaat ttatatggtg tttttgcaaa
     8161 aatcgtaaaa agactagatt atgataccga taaaaagcta ttaatgaagc ttatgcaaga
     8221 aatgacagat cagcctaacg atattagacc ttttacggaa tatgcagaac agacttctgg
     8281 aacagacatg tccgtattat ttatgtctac agtttatgat attcgacaag gttcggcaga
     8341 tttggatgtt attgaagagt tggatcgttt agcttctgaa gagttaatgg ccggaatcga
     8401 ttcaatcatt gactataagt cgaggcgttt tgtcttcttt cctacaaaaa ttgcaatgac
     8461 ttcatttatt ttagttgtcg gttttgcagt aggcgttctt ttcatgaacc taaaagatat
     8521 taactttggg caataaagga aaggagaaag tcaatgcaag aacaatccgt tatggaaatc
     8581 attaaatggt ttataggttt aatgatgatt atggcaatgg tttctatagg acttttttgt
     8641 gttcaattac aagatattaa tactttcaag caacaagtaa attatcaaat tgaacgaaaa
     8701 ggaggtctga cgacagaagc tgttgaagca atcgacaaat attcggctac taattatgat
     8761 agacgtttta caattgaaag cgataagtta aatcagaaag tatcttatgg agaagaaatt
     8821 gattatacga tcaaagcaac tattccaatt caaattttac cgcttcctga tgtaacttta
     8881 tcgtttaacg gaaatagtgt ttctcaaata agatgagagg aaggataaaa tgcaagagaa
     8941 taatgtttcc agaataattt atttgattgg cggattgata attttatcct tagctattgc
     9001 cggtcttgta gagcattggc cggaaataaa gttattaata agaaactttt acgacaataa
     9061 aatgattaaa atgtaggagg tatagatttg gaagcaattc aagaaaatcg taaggataat
     9121 caagaaacaa gtgaaaaaaa caaaaaaaaa agaaaaaaga aagtagataa atttacggaa
     9181 atgaccgata aaatcattga aaagaaagga cttaaaccta aagactttga ccgtcaagca
     9241 atcaaagaag cacgacaaaa actgtatgat gattttgtta aagaaaacat atcacagctt
     9301 ttagactaac atttaggggg aaataaaatg aaaaatttag ttatcagcaa gtttgcaatg
     9361 ttaccaagaa tggatttttt cgataatgta agtaagttta tgtcaaatat gacttcaaaa
     9421 ctacaaggaa tttcactatc tgtaattatc ttttgtattg tggttactgg tttgatgttt
     9481 cttttcggag aagggccaag tcgtactgct aaaaaatggt taacttatat cgtgattggg
     9541 gcaataatta tcttcggagc ttcaactatc ggacaaacga tcaagtccgt tggtggtttc
     9601 taaggggaag cttcttagaa ctaaaaaatt cgcaagtatt gcatgaaaga gcattgagtg
     9661 attaatgctc ttttttattt tgaaaaacta taaactaagg agatttaaac tatgaaccaa
     9721 cgattcgaat ataattttga agatgtagaa cctaagttac tgaaaaaagg aaaaggatta
     9781 aaaaagaaaa ataaatatac tctcaaacaa gcagaagcat tagtaggatg gattcaacac
     9841 aattggtcag acaagacaac aattaccttg atctgttcag acacagaaga aggaacaaag
     9901 tatgcttttg atggaattga aattactcca ttttcgattg gcggacaaga aaaattattg
     9961 tttcctgata ttgaaggaca aattttacaa gcgccggaca gcatgatttc cgatcctaat
    10021 aaactgattt tggatattaa cgatcaatac aaacacgaac cagacgtagc agaaccaaca
    10081 aaagaatcaa agtcaaaatt aaatttgaag ctcccttcag tagtattacc atttgctaag
    10141 aagaaaaata aacttatgaa cgaattgatt gaaccagaag aaacggatat ttatgaagaa
    10201 gaattagaag aacaagaaga gatcgaagaa ttagttgtgt cttctgaaga aacagaagaa
    10261 gtagaagaaa ttgaaactgt ttctgaaaat gaagaagaaa cagaagaaat ctttgacttt
    10321 gaagatgaag aagaagtgga aaatgtacag aaaggcgatc tatctacaag tagtcaaaat
    10381 gggttggaag ctgtaaatga tccacaagtt ccaccatata tatcttcaca aactcccaat
    10441 tactctccac agtatcaagc gcctaatgtc ttacaaccat taagaaaaca cgaaacagtg
    10501 cagttagtta cgcttaaaga gtactgtgat ttgggagaag aaattgaaac ttcaatttct
    10561 caaatggtcg aaaagttgaa accagaatct ttattcaaat tcatagggat tccttctaca
    10621 ggtcttacaa atactcgtat tgatgaatat agaagtaacc atgctatgtt gcgattagct
    10681 gaagtaaaat ttgaaaattt aagagagcat tattcacggc aaattatttc ttttaaagca
    10741 gaagccctag atcgtttaag aactgcggta gatattgctt ggaagaagcc ttacgattta
    10801 gatgtgaaga aaaacaaggc cgaagagtta tcaaaaatgg aagcagaagc agaagctaaa
    10861 ttaaatgagt tcgtgaaacg tcaggaaaac aatgtaaatg ataaaatcaa aaagtttgag
    10921 atcgaacaag aaatagattt aaaaaacttt attgcaagac aagaggcaga taaagcggta
    10981 tttattgcta cagagaaaga tcggactcaa aatttaattg attctaaagc ggaatcaatc
    11041 aatgcagatt tacttgaaac aaaagataaa tttattgatg aagaaatgta caaaatgaaa
    11101 attgaaatga acaaaaattt atttgatggc aagcaaaaaa ttaaatcaga attggctact
    11161 gaactcgcta aggcaaatga taatgtttgg gaaaatgcgc tgaaatttat tcaagaaatt
    11221 caagatgaaa ttgaagctaa aacaccaatt tgggctgctg aaatcaagga gtttaatagt
    11281 ttagaagaac aagaacatga acgtatgaag caaactaaag aacttcaatt aaaagaggaa
    11341 agtattgaaa tcaagcgttt ggaagctgaa atgaatttga agcgtatgga agaattagat
    11401 catgaaaata aaatgcttaa aattaaactt gaaactgccc tttcaaaaaa tgagttatta
    11461 gctatggaac aagatacaaa gcaagtggtg aatggatcaa acagagttgg tgcacttaat
    11521 ttatttagta aacgttaaag gagaacggat atgagtgttt ttaataataa agttatgtta
    11581 gggaactgtt atgtgaacca cattggtttt tacgatggag gaacatacag agttttattc
    11641 ttacgtttat ctgtttttag ttactcaaaa gatggaaagg ggcattatga aaatattaat
    11701 gcacaaattt cttgtccttt agatagaaat ggggaaacca cgactacaag tagtcaccct
    11761 aaagccttga tgaataaatt tatctttgaa aagttggatc gcaatttggt tgaggggatg
    11821 aagataagta ttcatggaaa tattcgtgga acagaacaag tgcttcttaa cagtggttgg
    11881 aaaaactttg gtcaattatc gcctttagaa aaagaagaat atcaaaaaat tcctaaaaat
    11941 gaattagtaa caagaaatca aacatatatc tatatagaag aggtaagtat gccagaaaaa
    12001 gaagaattta gaaagtctca atctaaggta acaaaagaag atgtggaagt tgcagaaccg
    12061 aatcaagcag atgaaatttt atccgatgat actgatccag tgaatgatga aggagaggtt
    12121 attgaagttt ttgaagctga aattatcgaa gaggaagaag aaattaaaag ttttgataaa
    12181 agaatgtatc gagagaaacc aaaaggttat gtgaattttg aagatatgta ttatgacgaa
    12241 tattctaatg aaccaccgat caattagtgg gggtcaaata tgaagctagt acaaaacaat
    12301 gaagtgaaag aaataaaaaa cggctttgtt aaaaactcga acaaaatttt gggaaagctg
    12361 aaaaaagtag gtagtttcaa aaaaaataaa tatcatactg gaaaaattga gggagaagat
    12421 ttaccaaaaa gtttacaaga taaattgaat gttccgcttg tatttatagg tgttttttta
    12481 ggttcaatag tttttctagc aataacgtac ttattgaact ttttaaaagc tttgttagtt
    12541 gcaatcggac agtcagaaag tgggctactt ggtgtagagt tcgatcctaa gtttagtttg
    12601 gcatatctaa aaccacttgg ggatacgaaa caatacttta tgtgtgctgt ggttgcggta
    12661 ataggagtcg cttatttaat atatgggaaa ttaaatcatg aaagtgagaa aaatcttgtt
    12721 tacggtcaaa aaggagattc aagactttca actatcaaag aaattaagag agattaccat
    12781 gagataccag aaaaaacaga agtgtatgat ggtattggtg gtgtgccaat tagtcactat
    12841 caagataaat attatattga tagagacaca gtaaataccg ttgttttggg agcttcacga
    12901 tccggtaaag gggaaacatt tgttgttcct ttattagata atcttagccg agcaaaaata
    12961 caaagtaata tggtcgtgaa tgatccgaaa ggagaattgt ttagcgcttc aaaggaaaca
    13021 cttgaaaaac gaggttatcg tgtattagtg ctaaatattg atgatccact tgaatcaatg
    13081 agttttaatc ctttacaact agtaattgat agttgggcta acaaggacta tcacgaagct
    13141 agtaagcgag cgaatacttt aacttcaatg ctctttgctt caggaatgag tacagataat
    13201 gagtttttct ataaatcagc taaatcagcg gtcaatgcga ttattttaac gattgtagaa
    13261 cactgtttta acaatgattg cattgaaaaa attacaatgt acaacgtggc tcaaatgctg
    13321 aacgaattag gaagcttatt ttacactgat ccaaagactg gaaaagaaaa aaatgcttta
    13381 gatgaatatt tcaatacttt accacaaggg aatcaggcca agattcagta tggttctact
    13441 tcatttgccg gtgataaagc caaaggttcg attttatcta ctgcttcaca aggtattgaa
    13501 atgtttacaa gtgatttgtt cgggaagtta acaagtaaaa tgtctattga tttgaaagag
    13561 ataggctttc ctaagtccat acaatttaaa gtcaatacga atttagttgg aaagaggatt
    13621 agtatttcat ttttgagaaa agaaaatgat gtaattagat taattaagaa gtatcgagtg
    13681 aaagtaaaag ctttagggct atgtgtttta aattttaatg aatatcttca ggatggagat
    13741 atgttggata tacgatatga agaagagaaa tcgagagcat ggtatcgtat tgaatttccc
    13801 aaaaaacaag caaatagtca tgatacttct ttagtcacta aaaaattcaa gtcaggtaaa
    13861 aattattctg acttagaaat cagcacctta cgattaaaat acacggatca gccaactgct
    13921 gtgttcatgg ttattccaga ttatgatccg tcaaatcacg tacttgcaag tatttttatc
    13981 agtcaacttt atacagaatt agcaagtaat tgtaagcaaa caccggataa aaaatgtttt
    14041 aggcgagttc atttcttgtt agatgaattt gggaatatgc cggctataga caatatggat
    14101 gggattatga cggtatgtct aggaagaaat atgctttttg acttagtgat tcaatcctat
    14161 agtcagctag aaacaagata tgataaagct tttaaaacaa ttaaagaaaa ttgtcagaat
    14221 catattttaa tcatgtcgaa cgatgaggaa acgatagaag agatttcaaa aaaatgtggt
    14281 cataagacaa caataaatag aagtgctagt tctaaacatt tagatactga tagctcggtc
    14341 actagttcgg cagagcaaga gcgagtaatt acagttgagc gtgctagtca attgattgaa
    14401 ggggaacaaa ttattttaag aaaccttcat agacaagata caaaaagaaa taagattaga
    14461 ccatttccta tttttaatac taaagaaaca aatatgccgt atagatacca atttttagca
    14521 gaagactttg atactcaaag agatattaat gagattgata ttgcatgtga acatatcaat
    14581 ctatctttac aagataacca aattccatat gcaaggttta tcaaagattt aaaaacacgt
    14641 ttggagtatt caattattaa taatattcct attagtgaag aagactatca ggattatcta
    14701 aatttatcag gatcacaaca aacaattaat gaagaagagc tgttaaaact ggtaaatacg
    14761 gaagtaaaaa gtcaagatat ggaaggtcaa gttttatcag aacaagaaat gaaaattaat
    14821 atttatctaa aggaaagtca aaaggaagca atagaattag taaaagtaat taatggaagg
    14881 ttagctgatg aaaattcagc agatatggtt ataaaaacca ttaattcaca aatccttgat
    14941 acgcctttca ttcaatcttt aatcaatgat tctatagcta ttcataatgt tcaagagagt
    15001 aaggatcaaa ttatgatcct agaacaacaa ttagctaatg cttatgagtt agcagtgttt
    15061 aaaacgaaaa attcaatact gaaaaataaa attatcaagt tgaaaaatgc tatgactaag
    15121 ctagcaaaag caatttagag agaagggaag aaatattgac tgaatctatt aattggagaa
    15181 aactaaatgt gcaatggtta aagtataaat ggccaatcat agtttcccta ataatcattc
    15241 tatttatggc ctatccgcaa cgagtttttg cgttgccgtg gattacagac aataaagagg
    15301 tattaaaatt tttaacaaaa tatcaagatt atcttcagtt tactaaaggt ggttttggaa
    15361 gcattgtcgt tcaaagttta tcgtgggggc tgattagagg tgcatatttt gtttgtaaat
    15421 cagcagaaaa ccttgttcca caatcgctaa gtttgtttag ctttgttgaa agcagtagtt
    15481 taggtgctgt ttatcaatct gtattaaaca cggtggttgt aggattaatg atcctttcat
    15541 tgatgtttgt tggttacaag atgattactg gaaaaggaac agtggattta aaatcggttg
    15601 gaatgaacgt agtgatgtct atagcattaa tacttttaat gccaaccatg atttctagtg
    15661 gtattcaatt tgctaaaaca ttttataagg actctactac gattacaaaa gctgatgggg
    15721 gcgttgcttg gtcattgatt gaggacggtg taactgattt agtatatatc aataaaaacg
    15781 atgcttatga tcggttgggt aaagatggcg tacaaaaaaa tgcgttaaaa gaaaagaatt
    15841 tcttttccta cgatttcagt gaagtaatca cagttgatac agctaaagat ttagaagatg
    15901 ataataaaaa agctgaatat cttcaatcta ggttgacacc agatggcgaa ggaaatatgc
    15961 aagccgttaa gattgatgat ggttggatgt cgatgttctc tgatagtttc aaaggagggt
    16021 actacaggtt tactaaaaat acttttgcat tgactttagg attactttcg ttagctgtag
    16081 cctatgtttt tagtattttt atcatagtca ccgctatttt agaactggca tttaagcgtg
    16141 tgttaggggt tcttgttttt gcaacagata ttgagacagg acagcgttca aaagttgttc
    16201 tatcagatat tctacagtgc tatttgactg taggctttca aggatttgga ttatccatgt
    16261 ttgcaatgtt tgtttcctat ttaggaacag gcggagggtc ttccgttaat ccgtttatta
    16321 aggctgtagc ttatgtatgt gccgtttttg ttttaatcaa aggcagtgga acagtcatga
    16381 gatactttgg tgttgatatt ggactcaaag aaggctatgg gcaacttgct tctgcttttg
    16441 gaatgggtgc aatgctgttt agaaaaggat caaatggatt taatcgtgcc aaaggaagcg
    16501 gaaacggaaa tggatcagac agcggagaag gagaagatcg aaaaccagaa aagaatttcg
    16561 gtgaaactct atcaaaaaaa gctggcaaaa ctggaagagc tttgggatat gcccatgaac
    16621 gtggattatc aggtttagct tcagatggag ctacaatggc tagtgaaaga gcaacaaaac
    16681 catttaagag tatgcgtgat atggctaatg atactaagaa taagttcaaa gaaggtttag
    16741 atgatggtac agtgtccgct attaataaaa atagcaaacc tatgttagct aaaaataaag
    16801 aagatgaaac tggaaaatac gctgattcca tgccaacacg tctttcgaat agaaaagatg
    16861 gtgctaaggt tgaaaatgcc gatagaatta tgtctagttc tgaacgtatg cgtgaagcaa
    16921 tgaaaaataa tgctgaatcg aataataatc ctgtaagtgc aattcagcaa aaagttcaac
    16981 aagatattga agaacgtaaa aatgctatgc acggtcaagc taagtctgct gaagaattaa
    17041 ttaatcagaa gcgacaagaa gctaaataca cgcctgaagc aatgaatcgt gaggaaatgt
    17101 taaggaaacg tgtagaaggg cgtacaggaa ctaatacgga cgaaaaagaa gcgttgacca
    17161 aagaaagaat ccaagaagct aaaaactcaa ataccggatt agaaaaattg gtcaaagaaa
    17221 atctacaaaa ttctacaagt agtcaaggtg gtcgatcagt agatgtccga gaaaatattc
    17281 aaggttcatt gaatggtcat gtcggacgga atgttgatgt aagagagaat ttacaaagtt
    17341 cttcaaatgg tcaaggtact aagacaattg gtgttcgaga aaatctgcaa agtagcagta
    17401 caagtcaacc aaaaacagta gatgttcgag aaaatgtaca aaattctaca agtagtcaag
    17461 ggtttaaatc agtggatgtt cgagagaatg tgcaaggtag cagtgcaagt caaccaaaaa
    17521 cagtagatgt ccgagaaaat gtacaaagtt ctacaagtag tcaaggattc aaaacagtag
    17581 atgttcggga gaacgttcaa aaagatagtg gagaaatgaa agaaaaaaca caaaaaatca
    17641 atatcgttga agacagaaag tcagcgaaaa aatttgattc aaatcatgaa acagtgatta
    17701 ttgatagtga aatccgtgaa aatgataagg gatcaaaacc aagacgaaga ttcacttatg
    17761 aagacaacga attattcaga gatacactta atgatcctaa tccacttttc gataatttaa
    17821 attaaattaa aagccggcat gagtgattat gccggctttt tatgaggtga aaatgatgta
    17881 tagaaatccc aaaaatataa aacaagagat aaagctattt ttcttctatt tagtcgattt
    17941 aggaatagta gccggaagcg tgatggcaag tgtttacttt gcaaaattaa tgccaatttc
    18001 accaatgatg aaatttgcac tgtacttatt agcatttgta gtgggtgttt ggatgtgcgt
    18061 tagaacgcct aatcacccta aagagcgaaa tattttaatg ctgtattatc tctttaaaat
    18121 ggatagaaac agataccacg aagtagagtt taaaagaaat agtaggggga aaattgaatt
    18181 atgattgttg ctgaaagtaa tgaaaataaa ttaagtggtg tttttgacaa attcttagaa
    18241 ctagttattc caaaagataa agatatgtgt gaacttttac catataaaaa aatattgaaa
    18301 gacggaacgt tagtgactaa tgacaataag tatcaagcct tttttaaagt taaaacaact
    18361 gacttaactt ctatttcaga agatggattt atgcgtatgg taaacaaact cacttattta
    18421 aatcgagtat atttagaacc atataaaatt tattcattaa cttatcctac tgaaacagta
    18481 aatcaagcga tttattggaa gcatagaata caggaggcaa agagaagttt attgagtaat
    18541 aatgatccca atttagaaac gtatctgaag tggaatctaa agctagctta cgataattat
    18601 gaaagagttg atctagtatc gactttacca gagttgatgt tcgttatttg tgtttatgga
    18661 aaaacacaaa aagaagtgaa aaatcatgcc gatgtaatga aacaggccgg tggtagagaa
    18721 ttagatttac aaagaattac tgaaggggat ttaatcaatg tgataactaa attgatgaat
    18781 cccaatactt ctttataagg cggtgcttat tatttgttaa agcactgtag aaaaggattt
    18841 tgtaaagtaa ttaaaggtaa aaatgctgct gatttaatct ttgaatggaa agaatctaat
    18901 ttaattaatg tacgtgggaa aaatggaagc ggaaagacag aaagagtgat ggctagtatt
    18961 gataattcaa ggcctagatc aagagcatta gtaataactg atgaaaaaaa tcactataaa
    19021 ggcatacgaa cgatagaaaa aaaatattta actaacaatg atttaaaagt agtagatgat
    19081 attttaaata tttatcctga ttttaattta gttgtttttg atgaaacaat tcctgtgaca
    19141 gaaataaaag gattctatca aagcttttcc aatctagcaa ataaatatga ggaagttctg
    19201 tttgtttgga ttacagaaga agatagtaat agcaagtcag cgttctttag tgaaaagaac
    19261 gcttttttac attctattta aaaaggagaa ttgaacatga ttgtaagtaa aaaactagca
    19321 agaaatctag taagtgaagg gtatgactta agattagtag aaaagtatca accgagcggt
    19381 ggaattaaat ttgatgagcg ttatatttct actggtgatg gatatgtaac ttcgattgct
    19441 gttattgagt ttgcagaaga tgtaaatagt cgatggttaa cggatataat ggcaattcca
    19501 aatactattg caactttcga tgtatgtacg gcggataaag aagacttatt acacaaaatc
    19561 aatacgtcta ttggagaatt agattaccga tcaacaaatg agaatagaac aactgacaaa
    19621 acagacgctt tactagataa atacaattta gaagattttg cacaagaaat tacgaaacgt
    19681 ggtgaagttg tcaaaactgt tcatgctcgt atttttgttt atagcgattc tttagaagaa
    19741 ttagagaaaa gaattagtga gattcgtaaa gatttggcta gtgtcaatca caaggcaatt
    19801 gttccgcaat ttagaatgaa ggatgaatgg atgtctttat ttcaagatgg catggaacaa
    19861 gaatcaaaat tatttgccaa gaaaggctta actgttccgg caaaaaatat tggtggcggt
    19921 attccatttc accacaagag tttgaaagat ccacgtgggt tttatttagg aactacgtca
    19981 actggtggtg cttttatatt tgatccattt tattctacga agcaaagacg gtcgtttaac
    20041 ggctttattt taggaaagat gggttttggt aagtcaactt taattaaaca gctacaggaa
    20101 ggcctacaag cgaaaaattg ttttattcga ggatttgaca agtcaggtga atttgaaggc
    20161 atggtgaaga aagcaggcgg tgtatacgtc gatttaggcg gtggtgatat ggtagtaaat
    20221 ccattgcaaa tttatgcaac agtcatgaaa aaagatcaat ttggaaatga tgttgtagat
    20281 gaatcaaaga gttttcaaaa tcatatcact aagtgtagta atcaaattcg ctttttagaa
    20341 cctgaaattg atacggcaac tgtacgtgaa tatactttga tgttacaaga cttttatatt
    20401 cattatggaa ttttgccaaa agaatggaga gaagcgagag acgacaacga acgaaatcaa
    20461 ttaaatacaa atatttgtaa cttgcctaat gattcatatc caatctatgg agagtttctt
    20521 aaatttattg aaaatcaaca attcaaaatt aaaaatgcta ctcctgaacg tgtccgttct
    20581 attgagctaa ttaagcttat cgttacggat atgtgtacaa cttatccgca aattttcaac
    20641 ggagtaacaa caatgccaaa ctttgataca acaaaaattg tttactataa cattgattct
    20701 attagtaaaa tgagtgcccc agtattccat tgccaattat ttacagcgtt aacgactatt
    20761 tggaacagtg ccttgcaaaa cggaaagatt caaaaagaaa actttaaaaa atatggcagt
    20821 gattattata agtatgcaca agatttcatg gttttgatcg atgagtgtca
//
LOCUS       DADVXB010000041        20292 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.041, whole genome shotgun sequence.
ACCESSION   DADVXB010000041 DADVXB010000000
VERSION     DADVXB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.041"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..2385)
                     /locus_tag="KB902_001156"
     CDS             complement(<1..2385)
                     /locus_tag="KB902_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6807996.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERV"
     gene            complement(2404..2808)
                     /locus_tag="KB902_001157"
     CDS             complement(2404..2808)
                     /locus_tag="KB902_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBB6807997.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(3040..3297)
                     /locus_tag="KB902_001158"
     CDS             complement(3040..3297)
                     /locus_tag="KB902_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBB6807998.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(3422..4354)
                     /locus_tag="KB902_001159"
     CDS             complement(3422..4354)
                     /locus_tag="KB902_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6807999.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTLCSKCNSFFGSEYVEEYIRFAEDNKNFLYNNTSLK
                     NGKSDLTHSIKKMNSLRVAKAIVAMFFSLNGDEDSMDKPFLDSVREYLSNPKSTLFPH
                     EDYKIIMNYYLPIGAPQNSKIKIPNDIVNDGDTHNVIKGFMPLDLSTGRKIRFSEIQY
                     EGIGFTLIDLKNSTFEIKEGLDLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNI
                     NYIDSGSDLLIRWQVITNFLMELKKYSNTQTKFS"
     gene            complement(4760..5515)
                     /locus_tag="KB902_001160"
     CDS             complement(4760..5515)
                     /locus_tag="KB902_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6808000.1"
                     /translation="MDFEQNVRLNFDLLSDNEKDMVFFIRTHKAQVVHMSIVELGEQL
                     LSSKSSVLRLAKKLGFRGYSEMKYSLEQSIVQSVIPPTDLIALLKDEINRTFQLADQT
                     NFQPILEQLKAAKTVVVYATGFTQNNFSKDFVNDLILSGRPAMLISGETNFEMLSHTL
                     TKDDFVIVTSLSGETPSIKSTIKNLNMNRIPLCGVTELGKNFLSEHSDFLLYYETREL
                     PSNLIEGSRSMIGLNILLSILSRKYREFILFDE"
     gene            complement(5622..7292)
                     /locus_tag="KB902_001161"
     CDS             complement(5622..7292)
                     /locus_tag="KB902_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6808001.1"
                     /translation="MNEWWKSSVVYQVYPQSFKDSNNDGIGDLMGIVEKLPYLAKLGV
                     DVIWLTPIFDSPLIDNGYDIRDYEKISENYGTLEDFKRLLEQAHQLNIRVILDLVVNH
                     TSNQHAWFIESQKNKENPYSDYYIWKDPKEDGSAPTNWGSTFGGSAWEYVESRKQYYL
                     HCFAKEQPDLNWENPKVRQSIYKMMKKWFDLGIDGFRMDVISLISKHPDYPDAPNSMP
                     YTKSYYVGASNGPRVHEFLQEMNREVLSKYDSLTVGETPNTNSRQAQLYTFPERKELN
                     MVFHFDHMHLDYGKYGKFSDVRFKLSDLRATLSEWQEALSDGWNSLYWSNHDQPRAVT
                     RFGDENEYRIESSKMLGTLLHMMKGTPFIFQGEEIGMKNVPFSSIDEYQDIETNYFYK
                     KMKEEGESDEYIKRAIYLKSRDNARTPMPWDHSKGYGFSNSDPWISFSPDNQQINVED
                     ALKNPNSVFYHYQKLISLRKNYPIIQHGTYKLINENDSAVFGYIREYKNELLVVICSF
                     SKESVPYELPKSLQGRKGVLLLSNYEQSPSELEDKFILRPYEALVYHI"
     gene            complement(7296..7715)
                     /locus_tag="KB902_001162"
     CDS             complement(7296..7715)
                     /locus_tag="KB902_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylglucosamine transporter subunit
                     IIBC"
                     /protein_id="HBB6808002.1"
                     /translation="MKKIIFASHHNLAVGLKDTVQYILPNVGEITAIAGYIDNSSIEE
                     KINEVMVRDNEDTDILIFTDMLGGSVNQAFIKYINQPNVYLITGMNLPVVLTILLNTL
                     NKRLTDNHIREAIQEAQDQLVYVNDYLKNIVVDEEDE"
     gene            complement(7728..8537)
                     /locus_tag="KB902_001163"
     CDS             complement(7728..8537)
                     /locus_tag="KB902_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6808003.1"
                     /translation="MNNEGNKLSKKDIRRAAFRYMFMACNIFNYENQQGPAVVYGLEK
                     ALRKIYPNDEDYRASLNNHFKYFNTTTWMANLLLGASLAMEEKDGVSSLDAVQSFKTG
                     MMGPLAGVGDTLVWVLYPTIMGSIAAYMGLEGNPTGAIIWLCLNLFFLFFRFKLFSIG
                     YTSGLKLVTALGSKLSIFTESASIMGLTVVGALIPSVVKMNVAVVFQSGKVKLPIQTE
                     ILDKIMPALLPAVLTIIVYKLIASKKMTVIQIIFSVIIFALILSFFGILKV"
     gene            complement(8530..9330)
                     /locus_tag="KB902_001164"
     CDS             complement(8530..9330)
                     /locus_tag="KB902_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6808004.1"
                     /translation="MEIIQGILIIILAVWVVLDQQGLVITTWFPIMIALFAGLIMGDM
                     TTAMVIGGTFQLMALGVANIGGSSVPNWGLAALVGIYVAIRTTNNIEEAKAVALAVGV
                     PVGMLGIQLDVLAKILNTYVTHAAQKAANKMDFKKMNQILWLGPVIFGLSTAIPTALC
                     VVFGDRIVRLILDFVPKWFTDGLSIAGSMLPVVGIALLLQVMPVKKYMTMLLIGFVLS
                     AYLNMPILGISIVGFALAYYFFTTEIKKAETASPVAANIVDEGDDFDE"
     gene            complement(9345..9821)
                     /locus_tag="KB902_001165"
     CDS             complement(9345..9821)
                     /locus_tag="KB902_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808005.1"
                     /translation="MGLVLARIDQRLIHGIVVTQWAGATKAKRLMVVDDQVSKDDTQK
                     AAMRMSKPAGTGMSIIDTDTAIINFKLGKYDSHNVLMIVKEPSTLVKLAENGIDIPKV
                     NIGIMFDGEGKQTVKKMVSVDEQEIADLKKLEAMGIPVTFHFVPSDPEEPLDVRIK"
     gene            complement(10216..10695)
                     /gene="rlmH"
                     /locus_tag="KB902_001166"
     CDS             complement(10216..10695)
                     /gene="rlmH"
                     /locus_tag="KB902_001166"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBB6808006.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            11123..12409
                     /locus_tag="KB902_001167"
     CDS             11123..12409
                     /locus_tag="KB902_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBB6808007.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTTSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSGF
                     GGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKDG
                     TKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANS
                     VTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKI
                     ASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQE
                     QILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKKV
                     GDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(12448..13053)
                     /locus_tag="KB902_001168"
     CDS             complement(12448..13053)
                     /locus_tag="KB902_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBB6808008.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLGADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWSGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(13258..13722)
                     /locus_tag="KB902_001169"
     CDS             complement(13258..13722)
                     /locus_tag="KB902_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6808009.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(13744..14064)
                     /locus_tag="KB902_001170"
     CDS             complement(13744..14064)
                     /locus_tag="KB902_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6808010.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(14208..15287)
                     /gene="pepA"
                     /locus_tag="KB902_001171"
     CDS             complement(14208..15287)
                     /gene="pepA"
                     /locus_tag="KB902_001171"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBB6808011.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            15487..15837
                     /locus_tag="KB902_001172"
     CDS             15487..15837
                     /locus_tag="KB902_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6808012.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            16060..17007
                     /locus_tag="KB902_001173"
     CDS             16060..17007
                     /locus_tag="KB902_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6808013.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(17064..18482)
                     /gene="pepV"
                     /locus_tag="KB902_001174"
     CDS             complement(17064..18482)
                     /gene="pepV"
                     /locus_tag="KB902_001174"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBB6808014.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            18631..19476
                     /locus_tag="KB902_001175"
     CDS             18631..19476
                     /locus_tag="KB902_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBB6808015.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     IENEA"
     gene            19480..19920
                     /locus_tag="KB902_001176"
     CDS             19480..19920
                     /locus_tag="KB902_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBB6808016.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            19970..20164
                     /locus_tag="KB902_001177"
     CDS             19970..20164
                     /locus_tag="KB902_001177"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808017.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
BASE COUNT         6193 a         4000 c         3332 g         6767 t
ORIGIN      
        1 aacccgttct aataatttag tcggatttaa tatggtcaat tgctccatta aattcgttag
       61 actaaaattc ttcagaatat tattgttcaa aactttcagt tcattatcat taaagtgtct
      121 attcaattga ttggagaatt tacttatatt cattcctaaa atcatatctt caattgaaaa
      181 gaattctaca tcttctagat gtggatttag tgttccaaca ataaaaagaa tattgttctc
      241 tttacgaagc tccgataaat agttttcatt cactaaagag taatagtcac acgtttctat
      301 gacaagatca gtatcccttg gaaagctatc ttcaagtatc ttttttaatt taaacgaagt
      361 tcctaatccg cttgcacaag aacagacaat catatccttc ttaatatttg atgattcata
      421 aatataatcc acattttgat tttcttttac ttgttcaaga atctgtttaa gcggtaaatc
      481 taataatatc tgatttgcaa catcaatagc cattcttgtt gaaacattgt ttagtagtcc
      541 gaattttttt tgagcgtcta gttccaaatt tagataaatt ttctccagtg aacccatatc
      601 aacaagtaaa ataatttctt catatccggt acactcttgt aagtatctat taattttgtc
      661 tgcaatctca ctacttgaag tcattagtgg catatcaatg gcgtcgtata tatatctctc
      721 aacgatccta ttagcagtac ttgctataca ggttgccgtt agatctccat gagccaaaat
      781 cagtgctaaa cgtttttgct gaaattcttt actacacatt aacttaaata aaataaccaa
      841 aacatttttt tgaatttttg ttaaataaat atcccctatt tgaataaaac gattgactaa
      901 ttgaacttct cgactacacc aactattaat atcattgatg aaggaatata atttatcgtc
      961 cgatgttaat tggatttgat aaatccaaga attcaaaaag atagacgtta tttgaagata
     1021 ataatagtca aattctattt gaaaatctct ctctatttcc ttaacatact gtctaaatcg
     1081 aatctcttga taggtgggat atgttaaagc tgaattattt tggatatcaa cattcttttg
     1141 tctaaaatat ctatcatatt tctcaaaaag ctgctgctta tcagtgtctt tcttccacgt
     1201 ttgataaaga tactctataa gttcgttgat attaaaaact tcgtctactt tttccaaatc
     1261 atccatttga atatatttta attcattctg tcttttcata accttcatgc cgttgaaatt
     1321 cacccattgt ggtaaatgat acatctgaat ataaagttct tccaaatcat ctaagaaata
     1381 aaaggcattg gcacaggtca attgaatgat atttttcaaa ttgccaacat tttcactaaa
     1441 gcgatagttt aataaaaaat ctaataattg ttgagatatc agtattttct ttgctagtct
     1501 ttcttcttct gatttaaaaa atatcttgat taactgtttt ctttcataaa gagaacgact
     1561 gtctaatgtt ggaagtgtta gctttacagg tattcttctc aacaaagttg ataatagttt
     1621 atcctcaggt ggttctgatg ttgcaaatat aatccagcaa cttgatgtgt accagttttc
     1681 attatcaccc atccgatgaa atttcctcgt atccataaac tgaaaaagtt tctcctgaca
     1741 ttcattgctc aatgcatgaa tttcatctaa aaataagact ccattattag ctaattctgc
     1801 taaacccttt cttccatctt cggctcctgt atatgcacct tttacatgcc caaaaaaatt
     1861 ggacaagaaa agttctggat tattggcata ttcactacaa ttaactgaaa tgaaagatgc
     1921 cttctcttct atataattat tggccaacaa atccttatac acataatttg ctaaatagct
     1981 ttttccagtt ccagtctcgc catgaagtaa aatgggtaag ccatttggcg gatagtagat
     2041 tgctgcttta atttgagcaa ttacatttcg cagacttcct tgacttccga taaccctttc
     2101 tattccaacc ctaaaagagc tatcatacca tttttccgct tcctctgaag agctaaaaat
     2161 ttgttgattt ggaactttct ccggtaaaga aaagaagatt actggacgag tattgatttt
     2221 tccaaattct ccatctttta cgaattcatt caaatattga gagacaatat tacgactaac
     2281 atttaatttt tcagatattt tctgtgctgt attgttcccc catttatttt taatctcaga
     2341 gttctctatg acataattga caatgcgttc ttttaattct tccatcacag cacctcctcg
     2401 acactattcg aattttgccg acagtatttt tccataaata tgacttgcta aaaaggcttt
     2461 gtttagatca ttcaattgga acgttgcttg ttttgcttga tccgctaaga cgttgaaaag
     2521 atactctggc gaaatcgcat accccaaaat atcaacgatt gttgcaatca gatcttcttt
     2581 tgattcttca tctgaaagta attcacgata caacatcgtt tgtttgctta ctgtgtcata
     2641 ttcctctaag gattcatctg ctaaaagaac cacttgttcc aacaaacggt cggataaata
     2701 tttatagaaa atcagcccca ataaataatt tttatattct gacgcatcca ttttactacg
     2761 gagattatct gccgcactaa ataacttctg atttaattct gcacccaaaa agatacactc
     2821 ctatctctta tttaaagttg ctatataccc tcttatttta gcatactcag ttttagaaaa
     2881 agcaaaaaaa taaagaaact tattcttgat aacaagctac gtgacgtata tccctaacac
     2941 aaaaatagcc atatcctttg gtttggatac ggctatttga tattactcat tcaattatca
     3001 aatcacagta ggtgtgaatc tcatcgggat cggcaatatc tacttctgat taggatcaaa
     3061 ggtgattttc tcaataaagg tgtgatacaa agctttaact tgcttcttct cactctggat
     3121 aagaaagcaa tccaaactag tcaatatctg ttggacatct ttgacttgaa tcggttcccc
     3181 ttgttgttga aagatcccta agatttcatt ctctcgaatt tgtaactgtc ttcgtttttc
     3241 agtcaattca tttaaacgat cttttaacat cggaaacaat tcgggactat cttccaaagc
     3301 agcttcctgt ttttgctcta atagttagat tttgcgtacc attttcttcg tttattttcc
     3361 ttcgattgct gattttaata tagtctaaag gaaatttata tttattgtat tctttataac
     3421 ttcaagagaa cttcgtttga gtattactgt atttttttaa ttccataaga aaattagtta
     3481 ttacctgcca cctaatcagc aaatctgaac ctgagtcaat ataattaata ttattttcca
     3541 tctccaacat tgtaagtact gttggtgtta atatagggac tttgtacaat tgtatttttt
     3601 tgattttatc atctgcacaa aggagatttt ttaaatctaa tccttctttt atttcaaaag
     3661 ttgaattttt taaatctata agagtaaaac caattccttc atactgaatt tctgaaaatc
     3721 gaatttttct cccagttgat agatcaaggg gcataaaacc ttttattaca ttgtgagtgt
     3781 caccatcatt tacaatgtca ttaggaattt tgattttaga attctgtgga gcacctattg
     3841 gaagataata attcattata attttgtagt cttcatgagg aaataaagta cttttaggat
     3901 tgctaagata ttctcgtacc gaatctaaga atggcttatc cattgaatct tcatccccat
     3961 ttaaactaaa aaacattgct acaattgctt ttgcaactct aagtgaattc attttcttta
     4021 ttgaatgtgt taaatcagac ttaccattct ttaaacttgt attgttataa aggaaatttt
     4081 tattgtcttc tgcaaatcta atatattcct caacatactc actaccaaaa aaactattac
     4141 atttactaca taacgtataa taaacatttc cttgaggttt ccttttaatc cccttcggaa
     4201 aatcaccttt tgtaaaatcg ctcttaagga aatcatctaa attaccagtt ctggtctttt
     4261 tacctccagt attccctgat tttttaggtg gtacatgttc tttagtaagt tcagtgtatt
     4321 tttcacataa aatacactta cccatctttt tcatatctat ccccactctt tttaattctt
     4381 atatacaatt atatttcaaa tattcattaa taaatatccc tatttatgat aaggacctac
     4441 ataactttcc ccctagatat tacgaatatc cagggggtgt tattgcatgc gtaacagcct
     4501 atgctaattt acaacataga tcgaagtggc ttagctctaa aaaataagcc gcatctttgt
     4561 cagatacgac tgtttagcat tgctcattca attagttgat gattttttca tcaaatttca
     4621 gatatagttg aatatttcct ttgttcagct tatcaaatgt cactttatca atgaatgttc
     4681 gatagatttc cttgttctca ctcttgaaac gattggctaa caacttttca acacttgctc
     4741 ctttgtttcg aaatggaggc tactcatcaa aaagaataaa ttcacggtac tttctagaga
     4801 gtattgatag caaaatattt aatccaatca ttgaacgact tccttcaatt aaattgcttg
     4861 gaagctctct tgtctcataa tataacaaaa agtcggaatg ctcgctgagg aaattttttc
     4921 ccagctcagt aactccgcaa agtggaattc ggttcatatt caaatttttg attgttgatt
     4981 tgatgcttgg tgtctcaccg cttagagacg taacgatcac aaaatcatct tttgtcaaag
     5041 tatggcttaa catttcaaag tttgtttcac ctgaaattaa catggctggt cgtcccgata
     5101 aaatcaaatc gtttacaaag tcttttgaaa agttattttg cgtaaagcct gtcgcataga
     5161 caactactgt ttttgccgct tttagctgtt ctaatatcgg ttggaaattt gtttggtccg
     5221 ctaattgaaa agttcggttg atttcatctt tcaatagtgc gataagatct gtcggtggaa
     5281 taaccgattg aacgatgctc tgttcaagag aatatttcat ttcagaatac ccacgaaatc
     5341 ccaatttttt tgctaaacgt aagacagaac ttttagaaga caataattgt tctcccaatt
     5401 ctacaatgga catgtgaact acttgagctt tatgcgtacg aataaaaaaa accatatctt
     5461 tttcattatc tgagagcaaa tcaaagttta gtcgaacatt ttgttcaaaa tccatttcct
     5521 cacctctcat atatacagaa ggaatttcgg ataaaacttg cgctgtttta tccgaaattc
     5581 tttcttattg cccaaattct aacacagttt ttacgtgctt gctatatatg ataaacaagt
     5641 gcttcgtaag gtcgtaatat aaacttatct tccaattcag atggtgattg ctcataattt
     5701 gatagaagaa gaaccccttt tcgaccttgc aatgatttag gtaattcata gggaacagac
     5761 tcttttgaaa aagaacagat caccactaat agttcatttt tatactcacg tatataacca
     5821 aacactgctg aatcattctc attgatcaat ttatacgtac catgctgaat gattggatag
     5881 tttttacgca gtgaaatcag tttttgataa tgataaaaaa ctgaatttgg attttttaaa
     5941 gcatcttcta cattgatttg ttgattatct ggcgaaaaag agatccaagg atcactgttc
     6001 gagaatccat acccttttga atgatcccaa ggcattggtg ttcgtgcgtt atcacgagat
     6061 ttcaaataaa tagcacgttt gatgtactca tcactctcgc cttcttcttt catcttttta
     6121 taaaaatagt ttgtttcaat gtcttgatac tcatcaattg aagaaaatgg aacatttttc
     6181 attccaattt cttccccttg aaaaataaat ggggttcctt tcatcatgtg aagtagtgtt
     6241 cctaacatct tactagactc tatccgatat tcgttttcat caccaaatct agtaacagct
     6301 cgcggttgat catggttact ccagtaaaga gaattccaac catctgaaag cgcttcttgc
     6361 cactcactta acgtagctct taaatcgcta agcttaaacc ttacatctga aaactttcca
     6421 tactttccat aatcaagatg catatgatca aaatgaaaaa ccatatttaa ttctttacgc
     6481 tcaggaaacg tataaagctg tgcctgtctg ctatttgtgt tcggtgtttc accgacagtt
     6541 aagctgtcat atttactcaa aacttctcga ttcatctctt gtaaaaattc atgcactcgc
     6601 ggaccgttgg atgctccgac ataataagac tttgtatagg gcatgctatt tggagcatca
     6661 ggataatcag gatgcttgct aatcaagctg ataacatcca ttcggaatcc atcaattcca
     6721 agatcaaacc attttttcat cattttataa atagactgac gaactttcgg gttctcccag
     6781 tttaaatctg gttgttcttt tgcaaaacaa tgtaagtaat actgctttct actctcaaca
     6841 tactcccaag ccgacccgcc aaatgtcgat ccccaattcg taggtgcact cccatcttct
     6901 ttgggatctt tccaaatata ataatcagaa tatggatttt ctttattttt ttgtgattct
     6961 ataaaccaag cgtgctgatt acttgtatga ttgacgacaa ggtctaaaat aactcgaata
     7021 ttcagttgat gcgcctgttc caataatctc ttaaaatctt ctaacgttcc ataattttct
     7081 gaaattttct catagtctcg aatatcatat ccgttatcaa ttagcggaga gtcaaaaatt
     7141 ggagttagcc agataacatc aacccctaac tttgctaaat aaggtaattt ttcaacgatc
     7201 cccataagat ctccgatacc atcattgttt gaatccttga aactttgagg atacacttgg
     7261 tagacaacac tacttttcca ccattcattc atccgttact catcctcctc atcaacgact
     7321 atatttttta agtaatcatt gacataaacc aattggtctt gtgcttcttg gattgcctca
     7381 cggatgtggt tgtctgtcaa tcttttgttt aatgtattca ataaaattgt caataccaca
     7441 ggtagattca tcccggtaat cagatagaca ttaggttgat tgatatattt tataaatgct
     7501 tgattgactg aaccacctag catatcagta aaaatcaata tatcagtatc ctcattgtct
     7561 cttaccatta cttcgttaat cttttcttct atagatgagt tatcaatata acctgcgatt
     7621 gcagttattt caccaacatt cggtaaaata tattggacag tatctttcaa tcctacagct
     7681 aaattatgat gactagcaaa aataattttt ttcattcttt attctcctta aacctttaaa
     7741 ataccgaaaa atgatagaat caatgcgaat atgatcactg aaaaaataat ttgaatgacc
     7801 gtcatttttt ttgaagctat caatttataa acaataattg ttaaaactgc aggtaagagt
     7861 gctggcatga ttttatcaag aatttctgtt tgaataggta attttacttt tccagattga
     7921 aaaaccactg caacattcat ttttacaaca gatggaatca aagctccaac gactgtcaaa
     7981 cccataattg aagcagattc tgtaaatatc gataatttac ttcctaaagc agtcaccaac
     8041 tttaaccctg aagtataccc aatcgaaaaa agtttaaatc ggaagaacaa aaagaataga
     8101 ttcaaacata accaaataat ggcaccagtc ggatttcctt ctagacccat ataagctgca
     8161 atcgagccca taatcgttgg ataaaggacc caaaccaacg tgtctcccac accagctaaa
     8221 ggacccatca tcccagtctt aaaactttga actgcatcta atgaactgac tccatctttt
     8281 tcttccattg ctaagctggc acctaataat aaattcgcca tccaagtcgt tgtattgaaa
     8341 tatttaaaat ggttattcag agaagctctg tagtcttcat catttggata aatttttctt
     8401 agtgcttttt caagtccata aacaactgcc ggaccttgtt gattttcgta attgaagata
     8461 ttacatgcca taaacatata gcgaaatgct gctctacgta tatctttctt tgataattta
     8521 tttccttcat tattcatcaa aatcatctcc ttcatcgact atattggcag ctacaggtga
     8581 tgccgtctct gcttttttta tttctgtcgt gaaaaagtaa tacgctaaag caaagccgac
     8641 gattgaaatt cccaaaatag gcatgtttaa ataggcggaa agtacaaaac caatcaagag
     8701 catcgtcata tattttttca ccggcataac ttgtagaagt aatgctattc cgactacagg
     8761 caacatgctt ccagcaatcg ataatccatc tgtaaaccac ttaggcacaa aatctaaaat
     8821 caatcgaaca attctatcac caaaaacaac acacaatgca gttggaatgg ctgtagataa
     8881 tccgaaaatc actggtccta accacaaaat ctgattcatt ttcttaaaat ccattttatt
     8941 tgctgccttt tgtgccgcat gagtaacata tgtgttcaat attttagcca acacatctaa
     9001 ttgaattccc agcatcccaa caggaacacc tactgctaat gcaacagctt ttgcttcttc
     9061 aatattattt gtggtacgga tggctacgta gatacctaca agagcagcta aaccccagtt
     9121 aggaacggac gatcccccaa tattcgctac acccaaagcc attaattgaa acgtaccgcc
     9181 aataaccatt gcggttgtca tatctcccat aatcagccct gcaaacaaag caatcatgat
     9241 gggaaaccat gttgtaatga ccaatccttg ttgatctaat acaacccaca ctgctaaaat
     9301 aataattaaa attccttgga taatttccat tccaattatc tcctttattt tattctcaca
     9361 tctaatggtt cttcaggatc tgaaggaaca aaatgaaaag taactggtat tcccatagcc
     9421 tctaattttt ttaaatcagc aatttcttgt tcatcaactg aaaccatttt ttttactgtt
     9481 tgtttccctt caccatcaaa catgatcccg atattcactt ttggtatatc gataccgttc
     9541 tcagctagtt ttactaatgt actcggttct tttacgatca taagcacatt atgactgtca
     9601 tacttgccaa gtttgaaatt aataatagct gtatctgtat caataattga catccccgtt
     9661 ccagctggct tactcattcg cattgctgct ttttgtgtgt catccttact gacttgatca
     9721 tctacgacca tcaatcgttt tgcttttgtc gcacctgccc actgtgttac cacaataccg
     9781 tgaatcaatc gttgatcgat tcttgctaat actaatccca tatctatcgt ctcctttttt
     9841 gttatcgttt acatcccaaa gtatatctac gccttgttac tttaacaata gttttagaag
     9901 tatcagggaa acagtcgtta tcttaggaaa tagtttcttt attaagagaa atttcccaca
     9961 aaaaaatagc ccaaccatcg attagatgac tgagctccct aaatttacgc tatcttttat
    10021 tactatttac ttctttttta tcgcaatcca aatttcgcca tcacaatccg tcaactcttt
    10081 tgagaaatca gtaaaggaga gttctgatgc ttgaaccaac tcatattctg aagttggcaa
    10141 ccactccgcg tatattgacc cactgacatc cctaaaaaag gtgcgaggtg gagaatattt
    10201 ttgatacaac tatccttatt tatgatatgg agcccccgca ttgatccgga aggcacggta
    10261 gatttgctcg acaaggatca gacgcatcaa ttgatgtgga tacgtcattt ttccaaaaga
    10321 gatctgagca ttgcttcttt tcatgacggc ttcgctgagt cctaaagagc cgccgataac
    10381 aaaaacaagg tggctttttc cttggatacc taattgatcg atttgtttag caaaagattc
    10441 acttgtagga tttttccctt caattgctaa ggcatagacg tattcttgtt ctttgatttt
    10501 cgctaagatc cgttcccctt ctttttcttt tacttgtctc atttgcgctt cgcttaaatt
    10561 ctccggggct ttttcgtcag gaacttcgat caattcgatt tttgcatagg cattcagccg
    10621 tttgacatac tcattgatac cttggatcag gtatttttct tttaattttc ctactgagat
    10681 aattttgata ttcatgtttt ctctcctttg gtcttcacgc tcactttgtt tattataatc
    10741 aattttttcg tctatatgtt tattttggct atttttgtta aaaagatttc cccaacagtt
    10801 atgcacaaca tccacaggtt tatacacaga aaacagtgtt attttacctt atttcatcac
    10861 attcattagg caaacatacg ttttataaga atttatccac tttatacaca ggctgtggat
    10921 atgttttatc ccttattttt ccaatcctat ccgcgtagtt ttacacagta tctgtggaaa
    10981 aagaaaatca aatattttca tctgaaaaca atgatttttc ctaaagtttt tcataaaaag
    11041 ttcacagtct caaagtagac taaagtcaac aaataagact atactaacag tagataaata
    11101 aatgtaattg gaggaggaac acatggatag aaaaaatgtg acaccaaaga tgaaaaaaaa
    11161 taaaaataat agcctctggc gtaagttagg tctggggctt gttggaggga tcgttggagg
    11221 actactgaca gctggcattt tttatgcagc gatgggcact ggcaacaata gttctactac
    11281 aagtggcaat caaaattctg ctggtgaaac agttgtggaa aacgtcaaag tcaatgtaga
    11341 ttctgatatc accaaagcgg tagataaagt tcaagacgct gtcgtttctg ttatcaactt
    11401 acaaagccaa aaccaatcaa gcggttttgg cggactattc gggcagcaag aagaaagtag
    11461 cagctcagat gatagtaatt tggaagctta tagtgaagga agtggcgtga tctacaaaaa
    11521 agatggaaat actgcttatg tagtcacaaa caaccacgta gtagatggac agcaaggtct
    11581 agaagtcttg atgaaagacg gtacgaaggt aaaagctgaa ttagttggaa cagatgctta
    11641 ttcagattta gcggtgttga agatcaattc agataaagtc gaaacggttg cctcttttgg
    11701 tgactcaagt gctctgaagg ttggtgaacc tgcgattgcg attggttccc cattaggatc
    11761 tgaatatgcg aattctgtca cttcaggaat catttcttcc ttgaaccgac aagtaacaag
    11821 tacaaatgaa tcgaacgaaa cagtcaatat caatgcgatc caaacagatg cagcaatcaa
    11881 ccctggaaat tctggtggtc ctttagtgaa tattgaagga caagttatcg gtatcaactc
    11941 aagtaagatc gcaagtactt ctgaatctac ttctaacgta agcgtagaag gaatgggatt
    12001 tgctattcca agtaacgatg tagtgaatat catcaatcaa ctggaaaaag acggaaaagt
    12061 gacacgtcca gctctaggta tcacaatggt cgacttatct gccgtttcta ctcagcaaca
    12121 agaacaaatc ttgaagattc cttcatctgt aactaacggt gtcatcgtga caaatgtcca
    12181 aacagctaca ccggctgaaa aagctggatt gaaacaatac gacgtcatta ctaagatcga
    12241 tgacaaagaa gtttcttctg gtgtagaact tcaatctgct ttgtataaga aaaaagtggg
    12301 agattctgtc aaaatcactt actatgaagg ctcgaaagaa aaaacaacta ctgttgaatt
    12361 gacgatcgat caatcggcat taaaacaaaa tcaaaatagt gaaaattaat aaaaaagagg
    12421 ttgtgacaaa gacttgtcac aacctcttta ttttggaaat gcttctccga ctacggcatc
    12481 ctcaggcaat actaagattc ctttttttgc tggagcattt ggcaaatgca attcacgagc
    12541 ggaacagatc attccatagc tatctacccc tcgcaaagtt cctgaccaga tcatcattcc
    12601 atctggcatc atagctcctg gttttgcaac gacaactttt tgtccagctt cgatattggg
    12661 tgcaccgcaa acgatttgca atactgtacc attgtctact tctgtctcag taatcgataa
    12721 atggtcagaa tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga tcttcggttc
    12781 atgatcagct ccaagctgtt cttcgaatcc tgcttctttg atcaatcgat tcaatttcgc
    12841 taattcctca tctgttaagc ttacttggcc gttcccttcg attgttagat gatcggagat
    12901 atggaaaaag ttccaagcaa caacttgacc ttgttcatct ttgatccgag caacattcca
    12961 tttgcgttca acggtgtttt ctgttccttt atcgtcggct atgataacca tcaaggtgtc
    13021 tccgacgtgt gctttgttat aagcaaaaat catgttcttt cctccattat cctttgctga
    13081 gatttatctt aacaaaaaat tgcattcact gcatgagatt tttttcatgc tttatttccg
    13141 aagaagcctc ttctggaaca ccatttattc gtaacaaggg actgtgacaa gaattttgtc
    13201 acagtccctt tactgtttta gttaattgat taaaaaggtc gtacaagttc cacttgctta
    13261 attacttggc tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat
    13321 cacgtagctg gctacacttc ctgtcataaa gcgttcgact gcatttagac ctgactgccc
    13381 aaccatgatt agatcgatct catatttttt tggcaatttg actgccatgg attcacgaac
    13441 agaaccatat gcaataattc cttctatatt tgtgtaatca acagatttcc catattcttt
    13501 acattcttcg atcatttcct tggctgtttc agtttgctga tcgactagat tttgatcaat
    13561 aggtgcatag cccataaagt tataaaattg ctgatcgatt acgtttgcta catatacttt
    13621 cccattatta cggcgagcca cttctaccgc ttttttgaaa gcagcaagtg cttgttcact
    13681 accgtcgata cctactaaaa tattcttata ttcttgattc atcttgaccc ctcctaacag
    13741 atgtcagcct tttgttacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc
    13801 tttattcact agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc
    13861 aaaaatgttc cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg
    13921 ccaatcagaa aagtcatttt caatttcagg catttgcggt ttgataaaac ggcagtctcc
    13981 gcaccagccg gcagtaaaga aaaatacact ctttccagtt tctacgtagc ctgctaattc
    14041 ttctaaacta tttgggataa tcattctttg tcctctactt tctgtttatg tatttttcaa
    14101 ttaaattata cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat
    14161 ctggcaaaaa gcaatctttt gccagatttt atagtttcac tatcgcatta ttttccgtat
    14221 acgatcgtat tcactgttga tttatccaaa cctttcagtg tttgaatcaa catttctcgt
    14281 gcagcttcaa aatcgcgaat actgaacatc gtttgatgcg tatggatata acgtcccact
    14341 acgccaatca ctgtacttgg gattccttcg ttttgtgtat gagcagcacc tgcatctgta
    14401 ccgccttttg aaacaaagta ttgataaggg atattgtttg tttcagcgat atccagcaag
    14461 tactcgcgca aacgaggaag catgatcaaa cctggatctt ggatacgcat caatgtacct
    14521 tctcctaaat gtccgaatgt gccatttttc gtcactgtat catctgctgc agagcagtct
    14581 actgcaaaga acagatctgg cttgaattta ttgacagaag ctttagaacc acgcaagcct
    14641 acttcttcct ggacattcgc gcctgcaatc aatgtatgac ctaatgtttc attttgcaac
    14701 gcttctaaag cttctaatac cattgtacag ccatagcggt tgtcccatga tttactgata
    14761 atattctttc cgttggctgt tttgatcgtt tcagcgtaag gaacgattgt gtctcctgga
    14821 aggacaccgt aactcattgc ctcttctctt gattcaaacc cagcatcgaa caaaatatcg
    14881 gttacttcta ctgatttttg tccgcttgtt cctcgcaata aatgtggggg aacggaagaa
    14941 gaaatacatg gataattctt accagtagag gttttaagtg taaaacgctg agcagaaaca
    15001 acgtaaggat tccagccgcc tagaggtacg actttaaaaa gcccgttttc ttggatttgt
    15061 gtcagcatga atccgacttc atccatatgt gctgcgacca ttacacgggg tgcatccgct
    15121 tcttcatgat ggcgcagacc aaaaatgccg cccaaaccat ctaactgtaa ctcatctacc
    15181 agcggttcca tatgactttc catataagcg cgaacatctt gttcaaaacc gcttgttcct
    15241 tgtaattctg ttaactcttt gattcgttga aatgtttttt cttccatatg ctattcgtct
    15301 aaatttcaga ctaaactcct ctcagactta tattgatctg cggataaaat atgatttttt
    15361 ctgcagaccg atcgtattta ttatagctta ttttttctgg tagcggttat ttatttcaaa
    15421 gaaaatatga gagtgtggta aaataagcac aaggagtaac aagtgagaag aaggaggtat
    15481 gtccacatgt atgaagaaag cgaactaagc tattttaaag gcgggttagc agttggaatc
    15541 ggtctaggat tattgagcgg ggtagcttca acgatttggt atcatcgcaa aaaagtattg
    15601 tcagcagacc aagtacttga aaatatcaag tcatcttttc taaaagaagg tgcaatcgaa
    15661 ggttcttgga tctcttttga aaaggaacct attaggaaat tcgccgttcg gtcgagtgct
    15721 tatcggggag gtctttctcg aatagaagat ggcgaaactg tttattatga atttttagca
    15781 gatgctcata caggaaccgt attagaaatt tcaagaaaaa aaggtgcaac agattaatac
    15841 gtcaaaaaag tgagagaacg aatacgcacc cactattcaa aagagaggta tcatgtcctt
    15901 cttttgtagt gggtggtttt ttagatagag ctttccaaac atatattcca gtattttctt
    15961 tttaaataaa tgatatttag cgggaaaaac tagcatttcc tttgattatg aggtattttt
    16021 aatttagctt ttgttttcta tagttaagga gagtgaaaaa tggaacaaca agaaaaaatt
    16081 gctgttctga ttccttgtta caatgaggaa gcaacaattt caacagtcat tgcagacttt
    16141 aaacgagaat taccagaagc agatatttat gtctatgata ataattcgac cgatcgaaca
    16201 tacgaattgg ccgttcaagg tggagcaatc gtaaaaaaag aacctcgtca aggaaaagga
    16261 aatgtgatcc gccaaatgtt ctttgatatc gatgccgact attatttaat ggtagatggc
    16321 gatgatactt atcctgcaga agctgtacat ggtttgctcg agaaattacg ttctggtgaa
    16381 gcagatatgg tcattggtga tcgcctatca aatggaacct actttgatga gaataagaga
    16441 cctttccacg attttggaaa taaccttgtt agaaatacaa ttactagaat gtataaaaca
    16501 aaaattcttg atgtcatgac cggctatcga ggattcaatc gtatctttgt caaaagtttt
    16561 cctattatga gttctggttt tcaaatcgaa acggaattga cgatccatgc tttagataaa
    16621 aaattcaagt tcgttgaaat cccaatcgat tatcgtgatc gtcctgaagg cagcgaatca
    16681 aaattgaata cattctctga cggattcaaa gtgatcatga tgattattaa aatgtttaaa
    16741 gattataagc ctttgctttt ctttgggatt tggaccatct tcttcttttt atttggattg
    16801 gtcacgggga ttcctgtgat tcgcgaatat atgctgacaa gctttattac acgcatccct
    16861 tctgcgattt taagtactgg attgatgact ttagcacttc tttcattagt aacagggttg
    16921 attttggata cagtcgtcac gaacgctaag aaagaatatg aattgaatct atatcatgtt
    16981 tatcatgaat accacagtag aaagtaaaaa aaggatcaag actgcaaaaa taatttgcaa
    17041 ttcttgatcc tctttttaat taattatttc gccaaacgat agatggcatc tgcatagatt
    17101 gctgttgctc tgaacaagtc atcaagactc ataaattcgt ttgcttgatg cattgtatca
    17161 gtatatcctg ggaacatcgc tccataagca acgccacgtt tcaacaaacg tccgtaagtt
    17221 ccgccaccga tgatttgttc gtagcctttt tctccagtgt ggtcttcata gacttgcaat
    17281 aatgtagcca ccaatggatc atccattggt acgtaatgtg gttccattac gcgagcacct
    17341 cgagtaactg ttgcgccttc ttgccccact gtttgttcga tgtcactttg caatccgtct
    17401 actgttacac cttttggaaa acggaaattc atattgatga agttcgcttc ctctgtacca
    17461 ttttcttcaa aagcaaatag tccagcattc attgtcaatt tgcccatttt ttcatcttca
    17521 taagcgactc ctagtttttc tccataaaaa tcttcatgga cataagcagc tgctacatgg
    17581 ataaattgtt tagcagatcc taggaattca tagttatcta agaacaatgc caagaaagaa
    17641 cctgcattga taccagattg tgggcttgca ccatgtgcgc ctttaccaac taattcgatt
    17701 tttacatacg tattgtccgc ttcaatcgtt ccgcttactg gatttgcttc gatgaattgg
    17761 taaaatgctt cttccatcgc gatagctgca tctgcacttg gtacttgaag tgctgcagtt
    17821 gctgttcctg gcaccatatt ttcgcgaagt ccggaaacaa aagatttcaa gacataatct
    17881 cctgcattgt cgcctttgaa gcgtaaagct aaagaaacat ttcctttttc accattgatg
    17941 attgggaatt cagcatctgg tgagaaacca aaatctggtt cttcttcatg ttcgaaataa
    18001 taagccatat cgccccagcc gctttcttca tcgctgccga ctacgaagcg aacttttttt
    18061 gatagtttca agtcaagttc tttaatgatc ttcatcgcat agtaagctgc catacttgga
    18121 cctttgtcat cgcttgatcc gcgtgcaaag atctttccat ccttgattac tggttcataa
    18181 ggatctgtgt cccagccatc tcctgcagga acgacatcca tgtgtccaaa tatccctagc
    18241 gtttcgtctc cttcgccaag atcaatatgc cctgcatagt tatcgacatt ttttacttta
    18301 aatccatcac gttcgccata agctaacata tgtttcaatg cgtcgcgagg tccaggtcca
    18361 aatggtgcat ctggtgttac ttttgagtca tcgcgctcgc tgttgacacg taaaagattt
    18421 ttcaagtctt caagcaagtc ttctttacgt gcttctactt ctttttgcca atcaattgtc
    18481 ataaagttaa tcctccactt atttaagtct tcgtgttcat gataccacaa attacagaaa
    18541 aaaatagttc aaaaaatctg acaattcctt ttcttatctg tttttctcta aaaaaaatat
    18601 acgctataat gagtaaaagg aggtttttag atgctgataa acgaacaact agtgaaaaga
    18661 gtcatcacac ctcgtccaaa aatttcacat aaaggaacat ttggacgtat cgttttgatt
    18721 ggcggcaatg aacaatatgg cggagcaatc attatgagtg ctttagctgc cgtacacagc
    18781 ggagcgggtc tcacgactgt agtaactgat gaaaaaaatc ggagtgctct tcacagtcat
    18841 ctgccagaag caatgattgt agtttggacg gatactgacc agtttctttc cgtaataaag
    18901 caagcagatg tactcttgat tggtcccgga ttgggtactt cttctaagag tttggaacgt
    18961 ttcaaacaag tactagaaaa ccaatcaaaa gaacaatggc tggtgattga tggctctgct
    19021 ttaagtttac ttgctgctaa tcatcttttg ctaccctatc ccgaacaaac tgtacttaca
    19081 cctcatcaaa tggagtggca acggttgagt tctctaccga tacaagaaca acgggataaa
    19141 gaaaacaaaa agaagcaaca ggaaatcggt gctgtgctcg ttttgaaaag tcatgagaca
    19201 aaaatttatg gtcaccagca cttctacacc aatcctttag gttctgctgc tatggcaacg
    19261 ggcggcatgg gtgacacttt agctgggatg atcacaggat ttttagccca gtttcctcaa
    19321 aatgaccaaa cgattgcagc agctatttat cttcatagtt tcattggaga ccagctggca
    19381 aaagaacaat atattgtttt gccgacacaa atcagcgaag cacttccgaa atggatgaat
    19441 tatttttgta aaaaatcaat agaaaacgag gcatgagtca tggagaaatt tacaggttat
    19501 gtgcgagaac ctttttatta tgaaacagat caaatgggga ttattcatca cagcaattat
    19561 atccgctggt ttgaagaggc tcgggtagcc ttattggtac atctagggtt tccctataaa
    19621 aaaatcgaag aatctgggat catcatcccc gttctggaag taaattgcag ctataaagaa
    19681 atgatccatt acggagaaaa agtgagcatc catccaacta tccaaaagta tacggggaca
    19741 cggttggatt ttagctacga aattgtggga actgaagaca aaaaattaaa aactactggc
    19801 agtagtaaac actgtttttt actttctgat tcgcaacgat tagtgaagct gagcaaagtc
    19861 aatccggagt tagatcagtt attccaagcg tacgcttctt tggatgatgt aaattcttaa
    19921 taaagaccgt ctaagcattt ttcttgtatt gtgtcgagta gttcgtataa tgaaaagaaa
    19981 aaagcaggtg atccccatgt atgtcgttaa agtaatgcac ggttacatcg ataaaactgg
    20041 ctgtcgcact cgggaaaaaa acttagacaa tctgctcatt ttcaaagaca aaaaagaatc
    20101 cgaagctttt gctaaaagaa tcggcggtcg tgtcaaaccg atacaagagg tacgaccaga
    20161 ttgattcaat atttttcttt tcgaggctct aataggcatg cctatcaggg ctttttttgc
    20221 agactgtgtt tttatgccca cacgatttgt aagcgattta tgttataata gattatatct
    20281 gcatagaaag ga
//
LOCUS       DADVXB010000042        20250 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.042, whole genome shotgun sequence.
ACCESSION   DADVXB010000042 DADVXB010000000
VERSION     DADVXB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.042"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(64..2139)
                     /locus_tag="KB902_001178"
     CDS             complement(64..2139)
                     /locus_tag="KB902_001178"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBB6808018.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2141..3058)
                     /gene="glyQ"
                     /locus_tag="KB902_001179"
     CDS             complement(2141..3058)
                     /gene="glyQ"
                     /locus_tag="KB902_001179"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBB6808019.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3444..4256)
                     /gene="recO"
                     /locus_tag="KB902_001180"
     CDS             complement(3444..4256)
                     /gene="recO"
                     /locus_tag="KB902_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBB6808020.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(4399..5298)
                     /gene="era"
                     /locus_tag="KB902_001181"
     CDS             complement(4399..5298)
                     /gene="era"
                     /locus_tag="KB902_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBB6808021.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5313..5708)
                     /locus_tag="KB902_001182"
     CDS             complement(5313..5708)
                     /locus_tag="KB902_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBB6808022.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(5692..6168)
                     /gene="ybeY"
                     /locus_tag="KB902_001183"
     CDS             complement(5692..6168)
                     /gene="ybeY"
                     /locus_tag="KB902_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBB6808023.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6185..8377)
                     /locus_tag="KB902_001184"
     CDS             complement(6185..8377)
                     /locus_tag="KB902_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBB6808024.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(8401..9372)
                     /locus_tag="KB902_001185"
     CDS             complement(8401..9372)
                     /locus_tag="KB902_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBB6808025.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10078..11457
                     /gene="brnQ"
                     /locus_tag="KB902_001186"
     CDS             10078..11457
                     /gene="brnQ"
                     /locus_tag="KB902_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6808026.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11613..12059)
                     /locus_tag="KB902_001187"
     CDS             complement(11613..12059)
                     /locus_tag="KB902_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBB6808027.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12086..12262)
                     /locus_tag="KB902_001188"
     CDS             complement(12086..12262)
                     /locus_tag="KB902_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBB6808028.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12424..12852)
                     /locus_tag="KB902_001189"
     CDS             complement(12424..12852)
                     /locus_tag="KB902_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6808029.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            12944..13804
                     /locus_tag="KB902_001190"
     CDS             12944..13804
                     /locus_tag="KB902_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBB6808030.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(13898..14248)
                     /locus_tag="KB902_001191"
     CDS             complement(13898..14248)
                     /locus_tag="KB902_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6808031.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14264..15991)
                     /locus_tag="KB902_001192"
     CDS             complement(14264..15991)
                     /locus_tag="KB902_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6808032.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(16205..17131)
                     /gene="trxB"
                     /locus_tag="KB902_001193"
     CDS             complement(16205..17131)
                     /gene="trxB"
                     /locus_tag="KB902_001193"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBB6808033.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17276..18712)
                     /locus_tag="KB902_001194"
     CDS             complement(17276..18712)
                     /locus_tag="KB902_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6808034.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     ENEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(18709..20112)
                     /locus_tag="KB902_001195"
     CDS             complement(18709..20112)
                     /locus_tag="KB902_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6808035.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
BASE COUNT         5469 a         4434 c         3637 g         6710 t
ORIGIN      
        1 ttataacaaa aaaacagaga cacagcacgt ttcgtgcatg ctctctgttt ttcaaacaaa
       61 agactatttt gtgatgattt gatccaagct tgctaatgac aaagccatgg cagctatttg
      121 actaagttgt gttagtcggt tcttacgtac tgctggttca tcagccatga ccatcgtttg
      181 atcaaaataa ttttcgatca gtggacgaag agcgacaagc tggtcgtagt tttcgtggat
      241 cgtttggtca gcaaaacttg ctttcattgc ttctactgct ttgtgtaatt ctttctctgc
      301 gtcgttttcg aacagctcag gatctacttc tgattgtttt tcaagctgcg cttttttcgc
      361 taagttcacg acacgtgtca aagcttccat tgaaggtttg aagtcttcat ctgcaagatg
      421 ttgtttgaac aattgtgctg ctgcaaatac ttttgtcaga tctttttgtt ccgcattcaa
      481 aacagcatcg atgacatcat gacgaatatt cttcgttgtc aataattggc gcagacggcc
      541 tttgataaag tcgatcactt gttgttgccc ttctgataaa ccaatgccga aacgatccgt
      601 atctttactg ataacatcgc taatcgtttc ttgcagaaca gacaaaggaa aggcccattt
      661 tttcgattcg atgatccgaa cgacaccgta tgcttggcga cgtaaggcat aaggatcgtt
      721 tgaaccgctt gggatcatcc caacagcaaa gaaagaaaag atgctatcta atttatctgc
      781 aatcgctaaa acagaaccta ctgtagactg aggtagctct ccttcactgg atataggcat
      841 gtaatgctca cgaatcgctg tcgctacagc aggtttctcg cctttcagca gagcatattt
      901 ttcgcccatg atcccttgca gttcaggaaa ttcccctacc atgttggtta ctagatcaaa
      961 tttatagatt tcagcagctc gttgcagatc catcaattct tcctcagata gtcctacttg
     1021 ttcgccaatg atacgggcaa tgacttgtac ccgttgcatt ttctcataga tactaccgat
     1081 tttttcatgg aaagtaacag tttttagttt ttcaacgtat tggtcgattg aagctttctt
     1141 gtcttcatta taaaagaatt ccgcatcttc taaacgagcc gtcaatactt tttgattgcc
     1201 tcgaaccaca ttttccaatt ttacccgatc accattacga gcagaaataa aatgaggaag
     1261 cagcatacct tgatcattcc gtacctcgaa ataacgttga tgttctttca tagaagtgac
     1321 tagtacttct tcaggaacag aaagatattt ttcttcgaag tcgccagaaa agacagttgg
     1381 atattcgact aaattgttga cttcttctag taaatcttcg tctagatcaa taacccaatg
     1441 atttttttcg gctaattcat tggcttgtgt aacgatcatt tcttgtcttt tttgcggaga
     1501 cgcaatgacg aattgttcat tcaatttttc ttcatattct tttgcatgcg caaatgtcac
     1561 atcttcgcct aagaaacgat gacctcgaga ggctctgcct gttttgacat ccaagatttc
     1621 gaatgggatt acttcgtcat ctaacaatgc cacgatccag tgaatagggc ggatatattc
     1681 aaaatcgtat tctgcccaat gcatcgttac agggaaagtc aggcttttaa tgacatctgc
     1741 taaacctgtc aatacttctt tggattcctt accatgagtg tatttcgtta catagacata
     1801 ttccacacct tttaattctc taaaagtgat agcgtctgtc gtcagacctt gtccgcggac
     1861 aaatccttcc gctgctttcg tccagtttcc atctgcgtcc aaagcaattt ttttggctgg
     1921 tcctttgact tcttcttcac tgtccgcttg tcgttctgga atgtttgtta ctttgattgc
     1981 taaacggcgc ggtgtggaaa atgtttcgat cgtatcataa gtcaattggt tttcatctaa
     2041 aaattttgct gttttttctt ctaattgttt catgcttggt gtgacaacat gagcaggcat
     2101 ttcttccagc ccgatttcaa gtaataagtc ttttgccatc ttattcagcc tccttcacgt
     2161 tttctggatt tgctgtgttt ttattcaaca aagggaatcc taatttttcg cgttctgcca
     2221 caaagatttt ggctacagca cgagccatgt tgcggatgcg agaaagataa ccggcacgct
     2281 ctgttacgga tactgcaccg cgggcgtcta ataagttgaa tgtatggcta catttcaaga
     2341 tataatcata cgccggatga acaagatttt catcgataca gcgtttagct tctttttcaa
     2401 aacgatcaaa gttgcttagt agcaagtctt ggtcgcttac ttcaaaagaa tatttagaat
     2461 gttcatattc tggttgtttg aagatctcgc catatttcac gccatcagcc cattctaaat
     2521 catagacact ttcaacttct tggatataag aagcaagacg ttctaatcca taagtgatct
     2581 cagaagttac tggtttacaa ggcagtccac caacttgttg gaagtacgtg aattgtgtga
     2641 tttccattcc gtcaagccat acttcccaac ccacaccggc acagcccatg gatgggttct
     2701 cccagttgtc ttcaacaaaa cggatgtcgt gttctagtgg atcgattcct aaaaggcgca
     2761 agctttctaa ataaagctct tggatattct caggtgaagg tttcatcacg acttggaatt
     2821 gatgatgctg atacaaacgg tttgggtttt cgccataacg tccatcagct ggtcggcgag
     2881 atggctctac gtaagcagca ttccatggtt ctggtccgat tgcccgtaaa aaggtatatg
     2941 ggctcatcgt acctgctcct ttttctgtgt catacgcttg catcagcatg cagccgtttg
     3001 atgaccaaaa tttttgtaat gttaaaatca tatcttggac ggtcaatttt ttactcatct
     3061 gttttgcccc tttcaatttt aaagcgttgc tgtcaaataa gaatacagga aagaaaacga
     3121 caaaaaatcc ctatgtctga ttacagacat agggacgaat aattcgcggt tccaccctac
     3181 ttccgaataa agattcggca gcttcattta tcgtactcgc aagtgcctct tcaaaaatcg
     3241 tttgggtccg gctcccactc tcccgaactc gctaaaccac gtgtttttta ctgatcttgg
     3301 tcaatgtacg tattcatttt gcagttttct tgtttctata atagatcctc tcagtgaacg
     3361 atctatttga tctacggtta ataatagacg gaactccctg tgtttgtcaa atggttttga
     3421 ttttttgttg tatgtttcat ttactattct tcttttttag gtagatcttt ttcagacatg
     3481 tctttctctg acgtctttaa tacgtgtgcc caagacttca tttgatcaat gaactttttg
     3541 cttttcaaat ggataccgac atattcatca tacagctggt cgatgagttc acggattgct
     3601 tgtttggttt cttctttcag atggattcca ctgattttat cataagaaat agctgaaaac
     3661 atccgaacga aataaacagc tcgaggatct gcatgataac ggtgatcatc catcgaccag
     3721 tgtctttcgc atatcacacc accatatttg gaagaatagt caaattttcc ttttgtttcc
     3781 ccacatacga cgcagtgtgt ccagattggt gcaattccga agcgttgcag tatttggact
     3841 tcaaaaatat tcgtgatgat ttctgcatca tctccttggt ccatccgttg cagtgcttgt
     3901 tgcgtaaact ggaacaaatg cgggtcgtac tgatgatctt cgattgccgc atctactaga
     3961 ttcaataaat atgtgccata gccgctcaaa aagatgtctt cttggatgtg tcgaaacgcg
     4021 tggacatctt tgacactgct taaaaatgac aaaccttcac ttcgaaaatt cccgatataa
     4081 actgcttcag taaaagggag caaagccgga gctaagggct gattttgccg atggatccct
     4141 ttgatataaa acatcatttt gccagaagat tccgtaaaga ttttgactaa tttatctttt
     4201 tctttgtaat tacggctaga taaaatcaag ccttttgatt ctgcaagctg gctcatattc
     4261 tccctcctaa aaaataaatc tggaaaagca gattctgccg atccagatca tttatgttgc
     4321 gatcttccgc agcttttctc aacacgcgga tttttatcca gtttatttct atacctaact
     4381 tacaagaagc tcagaatatc aatattcgtc ttttcggtag ccgaagtctt gcagatagac
     4441 ttttttgtct cgccagtctt tttgaacttt gacccaaagt tctagaaaga ctttgtctcc
     4501 taaaagattt tcgatatctt ttctcgcttt cgttcctact tgcttcagca tttttccgcc
     4561 tttgccgata atgatccctt tttggctatc tctttcgaca ataatcgtag cctggatatg
     4621 gattttatca ttctcgtttc gcttcatcga atcaacaacg actgcgacag aatgaggcac
     4681 ttcgtctcgt gttaaaaaca agactttctc acggatcaat tcagaaacga tgaagtattc
     4741 aggatgatca gtcacttgat catctggaaa atattgtggg ccctctggca tttcactgac
     4801 taatacatcc atcaaacgtt cgacgttgtt tccttctgta gcagaaattg gaatcacttg
     4861 tgcaaacggc atctgcgttg aataatcttc gatgattccc aacaactcgt ctggatggat
     4921 tttatcgatt ttattgataa tcagataaac aggagaatgc acgtttttta gacgttcaat
     4981 aataaaatcg tctccccgac cgcgtttttg atcagcgctg atcataaata agaccgcgtc
     5041 cacttctttc aacgcactgt aagctgcttc taccataaaa tctcctaaac gatgctttgg
     5101 tttatggatt cctggtgtgt caataaaaat caactgagct tctggtgtag tatatactcc
     5161 ttggatttta tttctagttg tctgcgcctt atcactcatg atggcaattt tttgacccac
     5221 gattcgattc aataatgtgg attttcctac attcgggcgg ccgacgattg cgacaaaccc
     5281 tgatttatgt tctggcatat acgttctcct ttttaattaa acaacaaatg atatatttta
     5341 gggacaaata aaatcaaccc aacgatgacg gaaaaacaag cggtcactaa aactgctcca
     5401 gctgccatat ctttgatttt tttcccaatc ggatgaaaat gaaaatccgt aaacatgtcc
     5461 acgacatttt caaaaacagt attgatgatc tctactatcc atacgagaaa aacagctaaa
     5521 agcagccata accattctat ccgatcaagc tggaaaatca cgcccataaa caaagcgagg
     5581 attccgaacg caacatgttt cctcatgttg cgttcttcct caaaaacggt tttgactcct
     5641 tggacggcaa attccacgga catcaggaaa tgtttgtttt tctctacgtt tttatctttt
     5701 aagtccatag gcatctaaga tctctttctg taaaccaaac atttctttct catcctctgg
     5761 tgtcatatgg tcatacccgt tgatatgcaa gaatccatga accgctaaaa agccaagttc
     5821 ccgatcatac gaatggccgt aagcttctgc ttgctctgca gcacgttcag tagagatcat
     5881 gatgtctccc agtacacgag gcaatggatt ctctccatct tcaaaaatca ctgggatttc
     5941 gtcttcgccc tcttcttcca aggcaaaact gatgacgtct gtcggtgcat cttttccacg
     6001 gtaatcacga ttgattactt ggatcgctgc attgtccatg aaagtaacag acatttctgt
     6061 ttcttctggc aactctaaat atgatgctgc aaattgcagc aagtcgtcga tttctttcat
     6121 tttctcttct gagacttggt ttgtttcatc catgaaagta atatccatta tacatcgctt
     6181 ctttctattc ttcttgttct tcttttatct tctcaacttc cgatttcatt ttaggatatt
     6241 tgatccgaga atggaaggta ctgcttaaac cgctgatcaa tgatttttct actttacgga
     6301 tttcttttaa cgtcaatcca ctgtcgtcca attgtccatc ggaaatacgc tcttcaataa
     6361 gattatggac aaaactttcg attttttcgc tcgttggatg gtccattgct cgtactgccg
     6421 cttcacaact gtcagctata ttgacgattc ctgcttcacg gctttgaggt tttggtccag
     6481 gataacggaa ttgctcttcc gtgacttccg ggttgcgttc ctttgcctta acgtagaaat
     6541 aacgcatcag cgtggttcca tgatgctgtc tgcaaatatc gatcaccatt tgcggcatat
     6601 tataatcttc caatattttg gcaccatctg tcacatgtcc aaagataata tgtttactgt
     6661 cttctggcaa taagaaattg tgcggatttt ccgctcctga aggcaagttc tcaacgaaaa
     6721 agctggcgtg tttgatcttg ccgatatcat gataatagca agctactcga gttagtaaag
     6781 aacgtccacc gatttctgct acagcattag cacttagatt ggctaccatc atgctatggt
     6841 gatacgtgcc tggtgcttct tccagcaact gtttcaataa aggatgatta ggattgctga
     6901 gttcatttaa tacgatcaca ctatcatcat tgaccatcaa ttcaatatag gggtgcagac
     6961 ctatcgtcag caagaatgag aacagtgcac ctgtgaatcc gcatactagc gttaaccaag
     7021 tcgttgcatc cccaaagctc attccttggt agataatcaa aatgacatcc atcatcacag
     7081 gaaaaataat gacccacata gcagcggata acccttgttc tgagatccgt ttgcgtctga
     7141 cgatcgttgc catgagacca gaaaatacat aggacatcaa aataactgtc agaaagttcg
     7201 tgccaatcga atcataaaaa atgaaaagtg cggatactgc ttgaaaaata ccagccatga
     7261 tccctgctct tcgattcaag aaaaagctta aaacaagtgg agcaaaagcc gcggggtaaa
     7321 acagcggaat ataagcagct tgttctgttt ggaagagttg gaaaaatttc attagtacga
     7381 cgcttactga cattgccgtc acgtagaaaa gtacgtattt tgttctttct cctgcatttt
     7441 ggaattgaag tgaattataa atcagtacac cgatttgaag caaaacagct aaaaccatgg
     7501 caatgagtgg gaaaatagaa gtcgtttgat tcgtcaatcc tagtaattcc aattttttca
     7561 tcgctgaagc atcaatttga tttccttcgc gaacaataat ttctccttgg aagatcatca
     7621 ctggttgtac agcttctcgt gcagattgtt ttaattcttc tgtctttttc tcattcaata
     7681 catcattaac tacaatgcct tgatccacta agtagcgaat catttgttgc tgctctgttg
     7741 tgacattcaa atattgaatc tgatcttctg cttcttgttt aaaagcttcc aattcgcttt
     7801 cacgaacttg tttactcatc tgttcgtcaa tgagcttcaa actttcatcc ctaaccgtgt
     7861 gaatttccgt ttcagtcatt tcaaatatcg tcgaataaaa attgttcggc agtttttggt
     7921 aaaacgcaac gttttctgca ttcacgtttt caaaattttt cttcagtgta gcaatccgct
     7981 cttctgtagt aggtttcggg atattttcat cttccttcgc cttatctacc ttgtcattat
     8041 aagatttgtt gatggtatca ttcgtcttat cgatcaattc gaataattgc ttgatccgat
     8101 tgttctggtc atctgccaga tctttttgat aagtatattc tggagtcact gcttctgctg
     8161 ccagttttct tctttgttcg gtttcttccg tgttctcaat cgttttattc gcacggatac
     8221 tctcttctgc tacttggcct tctctgaaat cattggcctt ttgtttgaca ctactaaatg
     8281 taacgccgca gacaatgata aaaaacaaga acagaaggaa aggcaatgct gcctttccga
     8341 gtttttcttg tagtttctgc agtgttttat tcaacatgtg cttatcctcc taagcaaagc
     8401 ttattcttga tgaagatccg ccttttcata agctttgatg atttcggcaa ctacagggtg
     8461 ccgaacaacg tcacttgctt caaaattaac aaaatcgatt tttttgattt gctttaatgt
     8521 tcgttctgca tgaacaagac cacttgtcgt cccacgaggc aagtctatct gacttgtatc
     8581 cccattgaca atcatttttg attgataacc gagacgggtc aagaacattt tcatctgagc
     8641 gactgtcgtg ttttgtgctt cgtccaagat aacgaatgca tcatccaatg tccgcccccg
     8701 catgtaagct aaaggtgcga tttcgatcac gcctcgttcc atcaatcggt tcgtatgatc
     8761 caatccaaaa atttggtata aagcatcata aacaggccgc agataaggat ccactttttc
     8821 tttcagatcc ccgggtagaa agcctaggtt ttcccctgcc tccacagcgg gccgcgtcaa
     8881 aatgattttt tgcacttcgc ctttttttag ggcagcaatt gctaatacta cggcaagaaa
     8941 cgttttccct gttccggctg gccctacacc aaatacgatg tcatgtttgg ctaccgattc
     9001 aacgtatttc ttttgaccgc tgttttttac ccgtataggt tttccattac ggtctttgac
     9061 gatctcttcc tcatacatct caacaaaata atctaatgta cctttttgcc ccatcttcaa
     9121 tgccgtcaca acatctggcg tacttacgtg gattcctcgt ttgatcaatt cctgtaatgt
     9181 ccgaatgact gaggcagcca aggaaatctg ggattgctca ccaatgatct gaatgatttc
     9241 tccacgtgta tggatggttg tttccgttgt ttcctcgatc agttttatat gcttgtcgtg
     9301 tgcacctaaa agcatgctga catcatcagc agctgtcaat ctaatctcta aagaactaga
     9361 ctcttccgtc aaaaatagac atcccctttt tttcgattca ttctttccta ttttaccata
     9421 ctcagaagaa actatatagc aaataagaaa aggttgtaaa agagtcgttt aaccatacgt
     9481 accaagaaac gttaaaaaat agccgtttcc attcgctaaa ggtctcgttt tgataaaaag
     9541 aagctgagaa tgtaagttat atgaaagtgg agaacaaaat attccgtttc attcagcagg
     9601 tattctctag gtatttttct tgtttcaaaa aaagaaaaca aaatagttaa aatattcttg
     9661 catttcaaaa aaaacaggtg tattattacg tcaacaaata aacatacagc aaagcgtcga
     9721 ggaaaacagt aggctattca acgatttatt cccagtgagt catgtaagtg agaaatgaca
     9781 ataaatcgaa tagacgaaca tcatttccga gtcaatgtcg aaaacgtaga tcattgtggc
     9841 tgcctccatt atcaggctag cggataactt tatcaaaaag cgtccgtgaa tgaagaagct
     9901 tttttaagcg aaaaaaggtg gtaccgttct agaatctaga gcccttttcc caagtggaaa
     9961 agggcttttt ttatatttta aggtggtggt tttcatggaa tctgatatta gtggcattac
    10021 taattgctgc aacgtttata tcgtcaatca aaatgataat tattggagga aaaatttatg
    10081 gaagaaacaa aaacttattc atggaaacaa ctattgatgg tcagttcact tatcttcggg
    10141 atgttcttcg ggtcaggtaa tctaatcttt cctgtccact taggtcaaat ggctggcgca
    10201 aactgggtca gtgctggcgt aggatttgcc atctcgggcg ctcttttccc attactagct
    10261 atcttagctg tagtagtgac aaaaagtgat ggtctgtatg acttagctaa acctgtcgga
    10321 aaatggtatg ctgccttgtt cttaatcctt gttcatttga cgatcggacc atttttcggt
    10381 acaccacgga cagctgctac tgcttttgaa atggctgcta aaccattttt gcctgaaaaa
    10441 tataattcat taggtatgtt tttattctct gctcttttct ttttacttgc ttatttcctt
    10501 actgtccatc ccacacggtt ggtcaaatac gtcggaaagt atctaaactc cttgtttctt
    10561 gcattgttag caatcatttt tgtcgtttct ttattccacc caatgggaaa tctaaatcaa
    10621 tctgctgcag atacttacca aacaaacgct ttaacaaatg gtgtcctaga aggttataac
    10681 acggttgatg cagtagcctt gcttgcctta agtgtcactt ttgtccatgc agtccgtgac
    10741 cttggtttca aagataaaaa agtcacagaa ttaacagcaa aagctggtag cctgagcgtt
    10801 gcgctagaag tcatgatcta ttttggtctt gttcttctcg gtgcgatgag tttgaataag
    10861 atgtctttat cagaaaatgg cggaactgca ctttctcaga tcactaattt ttatttaggt
    10921 aacttcggcg ctagcttctt aggagtgatg gtcacattag gtgtcttcac taccgctatg
    10981 ggactcgttg tttcttttgc gcaagatttc cataaactgt tccctaaagt cagttatatg
    11041 acatggctgc ggttaacgac tttcgtctct tttgtcgttg caaatgctgg tttagacaat
    11101 atcatccaat ggtctttacc agtattgatg cttttgtatc cattgtcgct tgcgttgatc
    11161 ttgctttcct taacagcaaa atttttccaa aagacaccat ttgtctatca agtaacgatg
    11221 ttgtttgctg ctgttcctgc cgtattggat atgctggcaa attcgcctgc tttagtgagt
    11281 caacaaagag ttgtagcaag catgctcgaa ttttatcatc atcacgttcc ttttgctgca
    11341 ttaggacttg gctggatggt cccaacgtta cttggttacg ctggcagcct actgttttat
    11401 tacgcctatc gcctatcagg gtataaacaa gaagcaaatg aactaccaga agaataacca
    11461 aatcaaacac aatttaacat aagaaatatt aaacaggaaa aaaccagcta gatgaaagaa
    11521 tcctattctt tcgtctagct atttttttgt tctctttttt acgcgcacaa aaaaactgcg
    11581 gacaatgatt gtccgcagtt taaatgataa aattaagatt gtaatagttc tttcacaatg
    11641 gcatttactt ggtttccatc tgcttttcct ttgactttag gcatgatcgc acccatgact
    11701 ttgccaaatt ctttcattga tgaagcacca gtttgtgtga ttgcttcttg aacaagttgt
    11761 cgaatttctt cgtcggaaag ttgttccggc atgtattttt cgactatcac aatttcactt
    11821 tttacttttt cagctaaatc gtcacgtcct gcttcttcaa actcatgcaa agaatcacgt
    11881 cgctgtttca tttcgcgaga caacaccgtt aattcttctt cttctgtcaa gtcgtgacct
    11941 tctttaatct gctcgttttg tatagatgac ttgatcattc ggatgacttg taaagattcc
    12001 ttatctttcg ctttcatcgc tgttttcatg tcatcgttta atctacttag tagtgacaca
    12061 ctaccaactc caattcatca cagaactaga attttttgcg ttttctagct gcttcagatt
    12121 ttttcttgcg tcttacactt ggtttttcgt agaattcacg tttacgagat tcttgtaaag
    12181 tacccgcttt tgacacggaa cgtttgaagc gacgaagagc atcgtcaagt gattcgtttt
    12241 tgcgaacgac tgtttttgac atgttaattc cctccctccg agcttaaaaa gtaaccgtaa
    12301 ttgttattga aatatatctc aaaaaacaag actgtcctgt aaatattata tctaatgctg
    12361 ttttgaccgt caaggaaatc ttgctttttt ttaaaattat caaatgttat tttatttaaa
    12421 tccttattga caattttcac atcttccgaa aatctcgaat ctatgccctt cgatcgtaca
    12481 tccaccgagc tgttcttcga aataattcat tggacacata tggatttctt tcgttgttcc
    12541 gcacaccgta cagataaagt gatggtgatg gccgatttcc ccttgacagc aatgaaaacg
    12601 aaacttcatc tctccattta aatcggtttc ttccagtaaa tcgatttctg caaaatcatg
    12661 gagatttcga taaatcgtat cgtaacttac tcctttgaat tcctgattca tatagtcaaa
    12721 aacttcttta gcggatacgt agcgattgcg cttcactaaa taagttaaca atgcttctct
    12781 ttttttagta tatttaaaac cgttattttt caatgtttct agtgattgtt caatcaatgt
    12841 ctgttttttc atgacttatt cctccaaatc aaaatgatta cgaagtacac attctagagt
    12901 atggtataat aaacataaaa aaaatgcaag tgaggtttta tccatgtctt ccgattctac
    12961 agaaatcgtt actttttttg tcatctctga ctctgctgga gaaactgcga caaaattagc
    13021 gcaagccact atggcccaat atcctaccgt tgagttcaat ttattccgca gaacatttgt
    13081 gacagatgag aaaacattga tgcaggcact gcaagatgca ctaaaagaaa aagcccttgt
    13141 cctgcacaca ttgatcaatc aagaattgat cgagatgacg cgttcttttt gtgaagaaca
    13201 tcaattattt agttttgatg tgatgactcc gccgatatca gaaatcgagc gcttaactgg
    13261 tatcaagccc attcggcaac ctggcgccct tcatttattg aatgagaact atttcaaacg
    13321 gatcaaagca atggaatttg ctgtaaaata cgatgacggg aaagatcctc gtgggtttct
    13381 agaagcagat gtcgttttgc taggcgtatc cagaacttcc aaaacgcctt tgagcttgtt
    13441 tttagctaac aaaaatttaa aggttgccaa tctacctttg atcccacaag cacatattcc
    13501 caaacagctt tgggagatcg atcctaaaaa aatcgtggga ctgacgaata acccagatat
    13561 tttaaacaat atccgtaaag aacggatgcg ctcttacgga ttaaatcctg atactgctta
    13621 ttccgatatc gaaaaaatac gagctgaact cgattttgcg aatgatcttt atgaaaaatt
    13681 gggctgcgta gtaatcaatg tcgcttcttt atctatcgaa gaaacagctt cacttatttt
    13741 gaatgcttta gacctagaag atcatagtta ttatggaact gaaaccaccg aagaaacaga
    13801 ctaacagttt ttcttgtctt tttcttaaaa aaactggact gtgtcagcga agaagattcg
    13861 ttgatacagt ccagtttgtc tctatttgca cctatcgtta ttgatgttcc acatgtttga
    13921 gcgtctggtt caaaatatcc agtacgtgag aatcatcaag actatacaaa atcgcttttc
    13981 cctcacgatg ggacttgacg acatggtttt ctcttaataa acgcagttga tgcgatacag
    14041 cagattgttc catttctact gcttgggtga ttgctgtcac attttgttcc ccgtctttca
    14101 gatacagcag aattttgaga cgagtggggt cactcaacat tttgaatagt tggctgactt
    14161 tctctacttt tgttttttgc gtgtctggca atccattcac ctccaacttg aaaaaagact
    14221 gacttctaaa gtttaccact ttttccatca gtctcaagtt tttttattct tctgtcattt
    14281 ttttgataat cgcttcataa gcggctactt tttcagctgc gtcttctgaa gagtttcctt
    14341 ttacaccgat ataaaatttg attttcggct cagttcctga aggacggata gcgatccagc
    14401 cattttcttc cagcgtatac ttcaatacgt cagatggcgg tgtcgttagt ttttctacgt
    14461 ttccttcacg gtctgttctc gtcaactctt tgaagtcttc tgtttggatg acttttgctc
    14521 cggcaaattc tgtcggtgct tcttcacgga atttttccat caaagcagag atttttgcag
    14581 aaccttcttg tccgctcatt gtcacagaaa tcgttttttc tgcgtagtag ccatatgttt
    14641 caaaaatcgt ttgcaagccg tcatacaacg ttttgccttg ttttttatag taagctgcta
    14701 cttctgctaa taagagcaat gcttgaatcg cgtctttgtc gcgaacgaaa ggtttaacta
    14761 aataaccgta actttcttcg aatccgaaca taaaagtatg ggaatgatct tcttcaaatt
    14821 gttgaatttt ttcagcgatg aatttgaatc ctgtcaatac attgaacatg gtagccccat
    14881 agtgttccgc aattgctgta ggcaattcgc tagaaacgat tgatttcaat accgctgcat
    14941 tttcaggtaa agtgcctcgc gattggtgtg cttccaaaat atattgagca aacagggctc
    15001 cgatttggtt ccctgtcaat acttcatagg agccatttgg caaacgaacg gctgcgccta
    15061 aacggtctgc atcaggatct gttgcaatca gtaagtcagc gccttctttc tcgccaagtc
    15121 gcatcgcata ctcgaaagca gagtgttctt ctggattcgg tgatttgact gtagtgaaat
    15181 ccgggtctgc gacagcttgt tctggaacta gtacgaattg ttcgaatcca gcttgtttca
    15241 acgcacgttc gcccaacatt tttcctgttc cgtgaagtgg tgtgtacaca agtttcaaat
    15301 ctttacccat tgtttccacc aattcatgat caatcgttac tgctttgatt tcttctagat
    15361 aagcggcatc cacttcttct ccgatgatcg tgatcaatcc gctatgttca gcttcgtcgt
    15421 cagataatac ttcaactttt aacggattgc tgacttcacg gacatatttc gtcaatgcat
    15481 ctgcgtctgc aggaggcatt tgtcccccat cttctccgta gactttatat ccgttgtaag
    15541 ctgctggatt gtgggatgca gttaccatga ttcccgcaaa cgtcttcaaa tgacggactg
    15601 caaaagaaag ctctggtgtt ggacgtaaac tttcgaatac ataagaaggg atattgtgat
    15661 gtgctaatgt tttggctgct tccatggcaa attctggtga ttgatggcgt gagtcataag
    15721 cgatagcgac acctcggcgt tttgtttctt caccttgtgt atccatgaaa cgtgcaagtc
    15781 cttctgttgc ttgtcttacc gtatagatgt tcattcgatt gatcccaggt cctaagattc
    15841 cccgcatgcc tgcagtaccg aattccaacg gtgcataaaa agcatcttca agtttttcag
    15901 gatcttcacc cagatcaatt aattgttttt ttaagttttc ttctaaattt tcttcatgta
    15961 cccattgttc atacacttgt tcccaagaca tgaaaataac acctctttct gaaatatggt
    16021 tcttaataag tatagcattc acttattaga tatgaaagta cgaggtctaa aaaacgctta
    16081 aatcaagaaa ggattctttt atcaagcacg gttgcaagta ttcgcataaa tcggattcag
    16141 tagatttcac gcgaaaaaaa agagtaaaag aacaattgaa accgttcttc cactcttttt
    16201 aaacttatgc agttgtttct tctaaagatt ccaagtattt atacacttgt tgtccagcga
    16261 tcccaccatc accaacagca gtagtgattt gtcgcaaatc tttttcacga acatctccga
    16321 tggcaaaaac gcctggtata ttcgtcttca tttcgttgtc tgttggaatc cagccagctt
    16381 cgttcgtcaa ccctgcttct ctaaatggtg cagttaatgg atccagtcca acatagatga
    16441 atactccgtc tgctgccaaa tcaaactcat tgccggtttt gacattacgt gctttcacac
    16501 ctgtcactac catttcattc ccaacgattt cgtcaacgac tgtatcccac ataaaggaaa
    16561 ttttttcatt cgcaaatgca cggtcttgga tgatcttttg tgcacgtaat tcatctctac
    16621 ggtggacgat gactacttca gaagcaaatt gtgtcaaata gatggcttct tctactgctg
    16681 agtctcctcc tccgatcact actagacgtt tgttacggaa aaacgcacca tcacaaactg
    16741 cacagtaaga aacgccacgt ccagcaaatt cttcctcgcc aggtacgcct aatttacggt
    16801 ggatacagcc tgttgcgata atgactgttt ttccttcgta agttttatct tcacaaataa
    16861 cttctttgtg gctgccgtga tccttgatat cttgcacgat tccataagca ttttctgtcc
    16921 caaatcttga aacaccttca tacatcttat aagctagatc aggacccatg attgaatcga
    16981 aaccaggata gttttcgatt tctgccgtat tgttcatttg gccgccaggg gcgccttgtt
    17041 cgatcatcaa tacggataag tttgaacgtg aagcatataa agcagcagtc atcccagcag
    17101 gacctgcgcc aataacgatt acatcataca tatgtagatt ctcctttact taatcaagta
    17161 agcatacttt acagccaatg cgaaaaaaag tctattgttc tgcttgcgtt tctcgaatag
    17221 ctttattata ctcgaaaaat ccgctgaaaa acaatagact tttacaaatc attgatcaat
    17281 cattcgaaag attttctcca tttgaatcaa ttactttttt ataccagttg aatgatttct
    17341 tcttcgaacg ggctaatgtg ccatttcctt cgttgtcacg atcgacataa atgaatccgt
    17401 accttttctt catctcacct gtaccagctg atactaaatc aatacatccc caagtcgtat
    17461 agcctaatag atcgactcca tctaattcta ctgtatcttt cattgcctgg atatgtgctg
    17521 ccagatagtc gattcgatag tcatcttcca cataaccatt ctcatcgggc gtatcgactg
    17581 cacctaagcc gttttctaca ataaatagtg gtttttgata acgatcataa atatcattca
    17641 tcgttattct caagcctaat ggatcaattt gccaacccca ttcacttgct tccagatatg
    17701 gatttttgac agaagcaaag atatttcctg cagtctgttc caagagttcg ttgtcagtag
    17761 tcgaaactcg agaagaataa taagaaaagg agataaaatc aacagtatgt tctttcagca
    17821 atgcggcatc cccaggttcc attttgatct gaatgccatt tcgttccatt tctttcaatg
    17881 cataagcggg atattctcct cgtgactgga catcaatgaa gaaataattt tctcgatctg
    17941 attttctaga agcccaaaca tcttcaggat tgcaagtgta tggataatat gctcctgctg
    18001 ccagcataca gcctactttg ttctccggat ctacttcatg agcaatcttc gttgcgatgg
    18061 cacttgcaac caactcatga tgtgccgctt gatatttgat ttgttcttca ttttctcctt
    18121 cttcaaaata cagccctgcg cccatgaatg gtgcatgaag gatcatattg atctcattga
    18181 atgtcaacca atatttgaca agtcctttat agcgattgaa gatgactcgg cacagatttt
    18241 cataaaaacc aacgagttct ctagaacgcc acgcaccata ttctttgatc aaatgcatcg
    18301 gacaatcaaa atgtgtaatc gtcacaagcg gctcgatccc gtacttttga cattctttaa
    18361 agacatcctc ataaaatttc aaaccagatt catttggctc attttcatcg cccattggaa
    18421 aaatacgact ccaagcaatg gacatccgat aagtcttgaa ccccatttct gcaaacaaag
    18481 caatatcttc cttataatga tgatacatat cgatcgcaat ttttgctgga taaaaatgat
    18541 ctttatcaaa ttcaaacatt ttcttttttc cagtaatgac aggaaaacgg tcttctccga
    18601 ttggcacaac atctacgttc gctaacccac gtccgccttc atcataacca ccctcgcatt
    18661 gattggctgc tgtagcaccg ccccataaaa aatcttttct gaatcccatc atacttcctc
    18721 cattacatgt gtattgcttg acaattctct tgccagttca tcttggactt cgattccttc
    18781 tgcttttaac cggctgattg tttccttgaa ttgcggtaaa tactgctgat gtgcaataaa
    18841 caactcatcc atgatccgtt ttgctgtctt tcctgatcgt ataagcggat tgatcgtaaa
    18901 cgcttgtaaa gctgttccat aatcaccagt cacggctgct tcgatcgtca gcaattccat
    18961 attcttcatt acttgcaacc agcctctttc agcagcagga agggaaccaa acgctacatt
    19021 tcgtgcgcct tgtgcgccaa cataggcagt gacttctact acacaatctg ccggcagatc
    19081 aggaacagct ccatcattct ttgtagacac cacgatctgt gtttctttat ttccatagat
    19141 cgaagcaatc gtttcacagg cagcatctga ataataagca ccacctcgtt tttgcaattg
    19201 ttcaggttta tgatccaatt ctggatcttt gtataattca aacagctctg cttctgtttc
    19261 tttcacttgt tgcgctcttg taccaatcgt ttgatattct tctaaagcat gttccaacat
    19321 ttcttcttca cggtagtaat agcggtggta gccacaaggg atcatgttca tttgttttaa
    19381 ttgttctttg aaaaacggga tgtcaaagat atttttcggc aatccattgt cttcatcgta
    19441 taaacgatca atcaaatctg ctgtgcggtc atttccttta ttatctgcta ctttgtgcca
    19501 atggaagtga tttagaccgg caaacttgta gatcagctct tcttttttct tgccaagcat
    19561 tgctggttct gtcatcgtcg ccattactgg cacattgcat aatccgatca ctttatccca
    19621 tttgccatat ctgataactg cttctgtcac catcccgctt gggttcgcga aattgatcag
    19681 ccaagcattt ggacataaac gcttcatgtc ttcaacgatt gccaaaacca ctggaacggt
    19741 acgaaaagct ttgaatatcc cgccagcacc atttgtttct tgcccaatca tcccataata
    19801 actagggatc cgctcgtctt tgattcgtgc atctaattga ccgacacgaa actgagtcgt
    19861 aacaaaatcc gcatctttca atgcttcttc ccgatccaaa gttgcataga tcttgacttc
    19921 atacggagaa gcatcccaca tacgctgaga catctgactg acgatctcaa gcttttcttt
    19981 tccttcttct acatctacga gccagatttc tcgtatcggt aattcctcat atcttttgat
    20041 aaatccttcc atcaactcgg gggtgtaact gctgcctcca ccaatcgtag cgattttgat
    20101 tccttttgcc atgttctcac tcctttgctt tttacacttt tattatcttt tttgtaaaca
    20161 aaacaaacaa tagaaattcg tttctttcca gtaacattta caaaagttag tgttttctac
    20221 tggatttttg taaatatctt gtcaaaaaat
//
LOCUS       DADVXB010000043        20034 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.043, whole genome shotgun sequence.
ACCESSION   DADVXB010000043 DADVXB010000000
VERSION     DADVXB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.043"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            79..969
                     /locus_tag="KB902_001196"
     CDS             79..969
                     /locus_tag="KB902_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HBB6808036.1"
                     /translation="MQLEINQEALPVYEALASNVRIKIIQLLAKNKMNVKELAQELGL
                     SSAIITVHIKKLEEAKIIKTERVGQKKISSLRVDHIDINFPEKIFNAFDTRETSIPIG
                     HYTNYFVEPTCGLATLSGFIGPVDEPKFFMDPNRMDGRILWFTKGFVEYQSPNFLSPD
                     EKLEMMEISMEISSEFPFSNNNWPSDITFSLNGITLGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRIMEHGTYMEGEPLSDVTIKDIPTYEDTWHLRVEVKEEAENIGGCT
                     LFGKGFGNYDQDIKIKMFYS"
     gene            complement(1111..2934)
                     /locus_tag="KB902_001197"
     CDS             complement(1111..2934)
                     /locus_tag="KB902_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBB6808037.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(3531..6236)
                     /locus_tag="KB902_001198"
     CDS             complement(3531..6236)
                     /locus_tag="KB902_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBB6808038.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPDIKEKLNKANEFVDYIPKVDEMGEKVVAFNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLNNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFESLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPILQQKLGLAADFIQNDWPTLKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(6542..7489)
                     /locus_tag="KB902_001199"
     CDS             complement(6542..7489)
                     /locus_tag="KB902_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBB6808039.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKSEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            7679..7948
                     /gene="rpsN"
                     /locus_tag="KB902_001200"
     CDS             7679..7948
                     /gene="rpsN"
                     /locus_tag="KB902_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6808040.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(8124..8486)
                     /locus_tag="KB902_001201"
     CDS             complement(8124..8486)
                     /locus_tag="KB902_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6808041.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(8497..9618)
                     /locus_tag="KB902_001202"
     CDS             complement(8497..9618)
                     /locus_tag="KB902_001202"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBB6808042.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYIHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(9634..9984)
                     /locus_tag="KB902_001203"
     CDS             complement(9634..9984)
                     /locus_tag="KB902_001203"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBB6808043.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(10114..11625)
                     /locus_tag="KB902_001204"
     CDS             complement(10114..11625)
                     /locus_tag="KB902_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6808044.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQSETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(11947..13299)
                     /locus_tag="KB902_001205"
     CDS             complement(11947..13299)
                     /locus_tag="KB902_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBB6808045.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKDFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTIFHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVPDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAVKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(13452..14528)
                     /locus_tag="KB902_001206"
     CDS             complement(13452..14528)
                     /locus_tag="KB902_001206"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBB6808046.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            14724..16469
                     /locus_tag="KB902_001207"
     CDS             14724..16469
                     /locus_tag="KB902_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBB6808047.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDSVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTEIVHEKEFGSFAFRASTSTEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(16718..17185)
                     /locus_tag="KB902_001208"
     CDS             complement(16718..17185)
                     /locus_tag="KB902_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBB6808048.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFCQALKKAIDQGLPSTEDSR"
     gene            complement(17169..18542)
                     /locus_tag="KB902_001209"
     CDS             complement(17169..18542)
                     /locus_tag="KB902_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808049.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGIMYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDAAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(18864..19352)
                     /locus_tag="KB902_001210"
     CDS             complement(18864..19352)
                     /locus_tag="KB902_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808050.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(19374..19976)
                     /locus_tag="KB902_001211"
     CDS             complement(19374..19976)
                     /locus_tag="KB902_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6808051.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         5822 a         4223 c         3665 g         6324 t
ORIGIN      
        1 ataaacaatg ctatttacac aaattagcaa atatattaac attcaagtaa atcaaacagt
       61 ttaaacggag gcgacacgat gcaattagaa atcaatcaag aagcattacc tgtctatgag
      121 gcacttgcca gtaacgtgcg aatcaaaatt attcaattgc tggctaaaaa caagatgaat
      181 gtcaaagagt tggcacaaga attaggttta agcagtgcga ttattacggt gcacatcaaa
      241 aaattagagg aagccaaaat catcaaaacg gaacgtgtgg ggcaaaaaaa gatttccagt
      301 ttgagagtgg atcatattga tattaacttt cctgagaaaa tatttaatgc ctttgatact
      361 agagaaactt cgattccgat cggtcattat acaaattatt ttgttgaacc aacttgtgga
      421 ttagcgacac tctctggttt tatcggtcca gtagatgaac ctaaattttt tatggacccg
      481 aatcgaatgg atggtcggat tctctggttc acgaaaggct ttgttgaata ccagtcaccc
      541 aatttccttt ctccagatga gaaactagag atgatggaga tttccatgga gatttcttct
      601 gaatttcctt tttctaataa taattggccg tctgacatta cctttagctt aaacggtatc
      661 acattgggca cctggacaag ccccggagat tttgcagata ttcgaggcaa gtatacgcca
      721 gattggtatc cagacaactt aaatcaatac gggttgttga agacgattcg aatcatggaa
      781 catggaactt atatggaagg cgaaccattg tcagatgtca cgatcaagga tattcctacc
      841 tatgaagaca catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc
      901 tgtacattat ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt
      961 tacagctaaa taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat
     1021 agagggcacc tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta
     1081 gagggtctgt ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct
     1141 gacaacgata ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg
     1201 gagaatattc tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata
     1261 gttttgtttc gctgcatttt tacttacgat atctacataa cggataattg gattttcaat
     1321 cgagcgataa gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc
     1381 tgcttcgatt tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac
     1441 ataatcaccg atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc
     1501 gactaataca agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg
     1561 aagctgttct gctacttttt tataatgatc atggatctta taaaaaatga acataacgat
     1621 tggcataatg atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat
     1681 gattgcatat gagatgaacg cacctgtaat attggcaatc gatttgctta accatctttt
     1741 tccttctttt ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac
     1801 gccgatagag tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac
     1861 gatcgaacct agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc
     1921 ttgatacatg tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc
     1981 agaaaaaccg gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta
     2041 atacaaaata ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt
     2101 ttcaggaacg atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa
     2161 gatcaatgcc atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa
     2221 tggtacagca ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc
     2281 tcgtaaaatc aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg
     2341 caatggcaca gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac
     2401 aaggataaat gtgtacaccg gaaataatag gaacgatgca gattccctca gaccacgaag
     2461 attcagcatc atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag
     2521 tgctggcacc gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa
     2581 catgtagtcg atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc
     2641 actgctgacg acgtatgctc ccccgccatg aggataagca tggatgattt gacgatatga
     2701 tagcgttaat gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat
     2761 ggctgcagca gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga
     2821 tgataacgca tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc
     2881 attttcagca gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta
     2941 aactccttta cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga
     3001 tgttatagta cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa
     3061 aacagaaaaa tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt
     3121 ttatgggctt tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag
     3181 ttctatcctt tttgatatct taacttttga aagagagatg taaggttgct ttctacccat
     3241 cattcttact actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa
     3301 agcttgcatc tgcggtaata agcccaacca aattaaaaac ataagaagct gtttttattt
     3361 ggtcgttctt attacttgat gcagagcaga ttttttacaa cctcttggta cacggtgttc
     3421 aatcagctga ccctcggcat tagctcaaaa aacggcaaaa tatgaggaat tatttttcca
     3481 tttttttctc taatactcag gtcaaaacgc tgatttcaca acctcttttt ttaatgaaaa
     3541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
     3601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
     3661 gtagcatttg gccagtaaat gcctcctgca gattcccgca acaagtttac cgcatgcgta
     3721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
     3781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
     3841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
     3901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
     3961 gtaacgatca ggctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
     4021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
     4081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
     4141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
     4201 aagaagtcac tttcttttgt tgcatctagt ttcaataatt tgatgacttc gcctagatcg
     4261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggatgccagc tttgatattt
     4321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ctctggcatt
     4381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgttgg ccaatcattt
     4441 tggataaaat cagcggccaa tcctaatttt tgctgaagaa tcggtaattc attgttgtat
     4501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
     4561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
     4621 gccactgcat tcgttacagt tgctttcgtt gagcttagca gagattcaaa atcgatctgg
     4681 tccgctttgc ttagcgcccc ttgtgcagtc ccaatcgtat cgatgacttg gtctaataga
     4741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
     4801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
     4861 acagctgtgt tcaaagcaga taggcggttt tgcagattgt ttagcaaggg ttttaattga
     4921 tttagctgat caataattgg ctgcaatttc gtatttccag cacttgtttg caatttagtc
     4981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
     5041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
     5101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
     5161 gtaacatcta cactatttgt gatgcttggt atcgcatctt tcagttgaga ggcacctgat
     5221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
     5281 tcctgtacct gttggatgat cgtcaagcct tgttttgctt cgtcaattcc ttgattcatt
     5341 gtctcttgga tcgaagcaaa atcaccgtcg atctctgcta gttgtttacc ggcattttgg
     5401 atctctggga ttttttcttg caaatcaagg atgatttttg cttggtcttt caactcaggc
     5461 attttgtcat taaatgcaac gactttttcg cccatctcat ctactttagg gatgtaatcc
     5521 acgaattcat ttgctttatt cagtttttcc ttgatgtcag gtagttgact ttgtaattcg
     5581 aggacttgct ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
     5641 tctttgactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
     5701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
     5761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
     5821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
     5881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
     5941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
     6001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
     6061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
     6121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
     6181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
     6241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
     6301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
     6361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
     6421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
     6481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
     6541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
     6601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
     6661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
     6721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
     6781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
     6841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
     6901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcacttt
     6961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
     7021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
     7081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
     7141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
     7201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
     7261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
     7321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
     7381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
     7441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
     7501 ccctttttct ttaagtttac gtttatgcct ttattttgac aaaaaaaatg tcttttcgtt
     7561 ttggcgcatg attcaaaaca aaataattgt cttttttcgc gaaacgtgtt aaattattta
     7621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
     7681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
     7741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgca aacttccttt
     7801 agatgctcgt ccagaacgat tgaaaaatcg tgatttgatc gatggacgcc ctcgcggata
     7861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
     7921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatataa aggaggaggg
     7981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
     8041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
     8101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
     8161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
     8221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
     8281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
     8341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
     8401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
     8461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
     8521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
     8581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
     8641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
     8701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
     8761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
     8821 gattccttca cctgctggga gttttttgac ttgaattaat tcagaaacca gctcaagtgc
     8881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
     8941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
     9001 gctgacatgt atatatcgag gaagttcggg aagttttttt agcacttcta taaagcgttc
     9061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
     9121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
     9181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
     9241 cgtctctagc ttacttttct ctaaaacagc agctgctgcc tgcaaccatt cccgtgtacc
     9301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
     9361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
     9421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
     9481 atgaccgtat ccgtttgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
     9541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
     9601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
     9661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
     9721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
     9781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
     9841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
     9901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
     9961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    10021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    10081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    10141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    10201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    10261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    10321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    10381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    10441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    10501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    10561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    10621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    10681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    10741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    10801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    10861 caattcatct acacggcgtt ttgtacgtcc gaagacgatt gttagttcag gtgtttgaac
    10921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    10981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    11041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    11101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    11161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    11221 gttgatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    11281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    11341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    11401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    11461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    11521 tgctagtgga atcgtttctg attggatagg tgttgcttct tcaaaaccag cgcgttcgac
    11581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    11641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    11701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    11761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    11821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    11881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    11941 agatttttat ttcatttgct gaagctgttc taccacttca aataagccca tgctgttgct
    12001 gccttttagc ataatactat ctgttgcttc aagattttgt tttacagcat caatcaattt
    12061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    12121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    12181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    12241 taacacagcg attctgcgtc cttttgttgg tagattttta aaagtatcta ataccagtcc
    12301 catggctgtt ggatttgcat tatagacatc gctcaaaata gctgcaccat ttcctgccgt
    12361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    12421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    12481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    12541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    12601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    12661 tccgtctggt acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    12721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    12781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca agacgatctt
    12841 ttctgtatct tggggcatgt gaaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    12901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    12961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcacctactt tttccaagta
    13021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatc
    13081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    13141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    13201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    13261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    13321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    13381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcttcttc
    13441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    13501 cctaattgaa tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    13561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    13621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    13681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttccggcac ttcggctgga
    13741 atctgcattt cgattttatt attgatatat ttggcttcat aatcatagaa tgctacgtct
    13801 tttacgactt cgccaggcaa agtcgtccga acatcttcat ttcctaatac agcaacttcg
    13861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    13921 gctaaagcat tttgcagctc ttctcggttt tctgcctttg taatgccgac actagaaccc
    13981 atattcgcag gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    14041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    14101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    14161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    14221 tccccgtttg gcccgtgtaa aactggaaaa acgatggctc cttcttcttt gatttctccc
    14281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    14341 tgcaagacat ctttgctagc aggtttttct gttagtaatg gacctttgac ccattgtcct
    14401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    14461 gaaaatgcgg aaagaatgga aacttcatgc tctgcgctgc gtccgccata tagtaaagta
    14521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    14581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagttggt ttctaaaaga
    14641 acaaacgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    14701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgtagccgc ttggcagaaa
    14761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    14821 aacaggtaaa aaaagccttt gaagaactag gccccacctt cattaagata ggacagatgc
    14881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    14941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    15001 tttcattatc agatatattc gatgattttt ccaaatcgcc ttttgcctct gcttctatgg
    15061 ggcaggctca tcgtgccaag ctgaagaacg gtgactcggt cgtcgttaag atccaacacc
    15121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    15181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    15241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    15301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    15361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaaccattta atgaacgccg
    15421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    15481 caaagctttt agttgagaac tttatgaaac aggtatttga tgatggtttt ttccatgctg
    15541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    15601 gccgaaaaac tgaaatagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    15661 cttctacaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    15721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    15781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    15841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    15901 ttgatgaaat caacttgcaa gaagtattca cacacgtcgt gacgatttgt catcaaaata
    15961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    16021 tgatccgcgt ccttgaccct gaagtttccc tcatggaagt cgcttcgcct tttgcccaac
    16081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    16141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    16201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    16261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    16321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    16381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    16441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    16501 agaaataaga agggattttg cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    16561 ttttcgaaga ggctacttct gaagcaccga gaataaaaaa tgtgaaaaag ctgttctgca
    16621 cccagtaata agaacaatca aaaaggaaca tggagcacat ttatcctgtt tccctgttcc
    16681 ctttttgatg tattcgagca taaataaaat accttcgtta cctactatct tctgtacttg
    16741 gtaaaccttg gtcaattgcc ttttttaacg cttgacaaaa agacatatga tctttctccg
    16801 taaagggttt tggacccttt gtccttatgc cagcttttct taactttcca ctatgataac
    16861 gttgttctag aagcgtgccg atattcgctt cgtcaaattc ttttccagag tgatggaaca
    16921 ctcggacgcc cttcggcaat acaagtgaag ctaaaccata atcttgcgtg atcaaaaagt
    16981 cattcttctt aaccataccg acgattttat aatccgcact atcagctccg cggtctacgt
    17041 agacgatttg gacatgatta gcgtattctt tggtcgtata atggtccaca ctggtcacga
    17101 taaccacgtc aagaccatag gattctccta attttatgac atcttctttt actggagaac
    17161 catctccatc aatgaatagc ctcattcttt ttcgccttct tccataaatg ataaacagtt
    17221 actaatccgc tcagtaaaag accaacattg atccattttg ccaagataag cagttgtaca
    17281 ctttctatcg gcactgattc atggttcagc gtgatcaata atagatggat tggctctccc
    17341 atttcttttg ctaaaacaaa caaaagcgtc atcaataaaa actggtggat cacactccct
    17401 ttattttgag tagtatactt gacaacgatc cggcgatcca ttggaatagc tgcatcagtt
    17461 tgataatatt ccttatttag ccagctgcct gttactacgt gccagaaact aagcagaaag
    17521 acacctatcg caaaaccatt tggaatcaag aggaccaata aagaagaact cagtccaagc
    17581 aattgcatag ccaatggaga ccatgttaaa cgtttcaaaa tccatggtcc gactattttt
    17641 gctgcaatca agcctgctgc ataaggcaaa tacataaaaa tcgaaagttt ttctaatccg
    17701 tacattatgc caacataaaa actgctaaat aaaaaaagga aattccctag cattccattt
    17761 agaaaagtaa acagatttag ccagcttggc aacttccatt ccttcttctg gtgtcctaaa
    17821 acaaacacga acaagatgaa cagcagcaag aaaccataaa tagcaagatc aaaaagcctt
    17881 tcatcgaata acaatcgggc atttctcaaa agaaacaata agccaaagaa tatcaaaaat
    17941 aaaacaagct ctcgcgtagc taccagattt cttttgatgt ctttgaaatc cagttcgtaa
    18001 cgcggataat gactaaccgt atggtaggcc atgacgtaaa aaagtgtata aatagtaaag
    18061 cttgctgcaa tctgagtcgg tgcaggcaac tcaatcgctt gatacaggag aaatagccag
    18121 atagctgcaa ataagtactt tttcccatcc atattgataa aaccttgcgt cttttcgtga
    18181 aaattgaccg tggtattagc aggtacaagc catgctgcac tcagccctag caaaacactt
    18241 gaaaaataaa ataaaggaaa ataaaatacg cctaatattc caagcaatga accagcacca
    18301 ccaatcagca gagcgatcat cagcaacgtg taactatcta gaccaaatcg tagactgttg
    18361 actaaaaata gtccagtcat ccgaaaggca taaaacagcg taaatggcaa aatcgtcagc
    18421 caattatgcg agtctgttag tcccaaaaat aaaagataag gaataaaaat aaccgtgtta
    18481 cttaagataa agggcgttgt ttgtgtaaaa ttacgcccaa atcgtttgag tttttcgaac
    18541 atgacaatgg ctccttaaac agtcttataa ctaatctgct cttcgatttt agcattaaag
    18601 gggaaataaa ccaattttac agaatatatt cttgtaaaaa aaaatacaga aagaagcata
    18661 agcttctttc tgcattttta cggtacttga ttactcaagc agacaagccc ttctccacaa
    18721 aagtcttgcc cgacacccct gcatccggca ggtgataaag atagaaatca attatcctgt
    18781 gcctccaaaa tcaattagga gctctgtaaa ccagagtcct tctcgacccg tcgcataaat
    18841 ttactttaac acagttccta tgtttatgcg agagcttttt tcattttata atcgaccatt
    18901 tgaaatcctt gaccgatatc tgaaataagt tcttctgtaa tctcaaatcc ttcatgctta
    18961 taaacctcga ttgcttgatg attcccctga ttcactcgca aaaagatctc tctttccttt
    19021 gtttgcgcag caagttcttc ataccagcga aaaactgaag aagtcaatcc ttgaccacgt
    19081 actttattta gcaaatataa tttacttaaa taaatttttc catttatctc ttcataagca
    19141 gtgtaaccga cagtcttttc ttcgcttttt aataaaaagt aggacacacc ttctgtcagt
    19201 tctttttgaa tctgtttttt tgactgataa gttttcagca tgtaatccac ttgtttttga
    19261 ccaatgatcg gcacaaaagc ttccggccat acttcttgta tgactgccat cagctcatcc
    19321 agttcatttt ctgttacttt tattttttcc atacacccac gtcctttttt acattataaa
    19381 tgaccttgcg cttgatggaa taaaaagagc atgatcatgc tatacacacc caccgaccat
    19441 ggtttcaaga aaatcacaat ctgcataaat tccctaaaag ataatttcgt caaaccagct
    19501 actagacaga tcaagtcgtc tggcgcaaag ggaagcagca aggtaacaac tagtactttt
    19561 ttaatatctt tcgtttttct tgtcagcaat tcatcaaatt tctgatactt ttttggcgat
    19621 aaaataagct ggacaaaggc tacgccatag taacggacaa gcaaaaatcc gattgcttcc
    19681 ccaatcacta ggccaataca actatataaa agcccaaatc cattgccaaa catcagcatg
    19741 cccgctactg aggagatccc tcccggcaaa ataggaatga tcacttggat cacttgcaac
    19801 agaacaaata tcatcactgc atacttgcca aattgctgga taaacgcttg caaagacgtg
    19861 ctcgatcgaa aaatcccatg atgataagca taaagaatca acacaaagaa aaaaaacaga
    19921 ccaataatgg gcatgatctg aagacatttt tgtaaaactg atcctttttt agacatctat
    19981 attccccaca tcttttttca tttattaaaa ctgcctcctt atgaactgaa cccc
//
LOCUS       DADVXB010000044        19786 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.044, whole genome shotgun sequence.
ACCESSION   DADVXB010000044 DADVXB010000000
VERSION     DADVXB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.044"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            90..278
                     /locus_tag="KB902_001212"
     CDS             90..278
                     /locus_tag="KB902_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808052.1"
                     /translation="MDIYKKLASKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPAD
                     FYRKMQIINYQPLAETHA"
     gene            complement(801..1754)
                     /locus_tag="KB902_001213"
     CDS             complement(801..1754)
                     /locus_tag="KB902_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6808053.1"
                     /translation="MKKLVVGILILASFGLAACGNSDNTSQADTKKSSTQAETALTIK
                     DSNGDQIEVPKNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(1777..2532)
                     /locus_tag="KB902_001214"
     CDS             complement(1777..2532)
                     /locus_tag="KB902_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6808054.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKKLVQEIGKTIVIVLHDINFAASYADEIIAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(2529..3488)
                     /locus_tag="KB902_001215"
     CDS             complement(2529..3488)
                     /locus_tag="KB902_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6808055.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFAWALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTFLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(3481..4431)
                     /locus_tag="KB902_001216"
     CDS             complement(3481..4431)
                     /locus_tag="KB902_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6808056.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFPQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            4581..5033
                     /locus_tag="KB902_001217"
     CDS             4581..5033
                     /locus_tag="KB902_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBB6808057.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPVEKEKPKKKKSFWDRLF"
     gene            complement(5121..7388)
                     /gene="gshAB"
                     /locus_tag="KB902_001218"
     CDS             complement(5121..7388)
                     /gene="gshAB"
                     /locus_tag="KB902_001218"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBB6808058.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEAIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDGIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(7575..8573)
                     /gene="ftsY"
                     /locus_tag="KB902_001219"
     CDS             complement(7575..8573)
                     /gene="ftsY"
                     /locus_tag="KB902_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBB6808059.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKIEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(8585..9394)
                     /locus_tag="KB902_001220"
     CDS             complement(8585..9394)
                     /locus_tag="KB902_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6808060.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(9403..12984)
                     /gene="smc"
                     /locus_tag="KB902_001221"
     CDS             complement(9403..12984)
                     /gene="smc"
                     /locus_tag="KB902_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBB6808061.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLLKEVAEKETEIQKAEASLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYVQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPNQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(13004..13690)
                     /locus_tag="KB902_001222"
     CDS             complement(13004..13690)
                     /locus_tag="KB902_001222"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBB6808062.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(14038..15819)
                     /locus_tag="KB902_001223"
     CDS             complement(14038..15819)
                     /locus_tag="KB902_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6808063.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(15845..16759)
                     /locus_tag="KB902_001224"
     CDS             complement(15845..16759)
                     /locus_tag="KB902_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808064.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(16786..17748)
                     /locus_tag="KB902_001225"
     CDS             complement(16786..17748)
                     /locus_tag="KB902_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808065.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(17748..18692)
                     /locus_tag="KB902_001226"
     CDS             complement(17748..18692)
                     /locus_tag="KB902_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808066.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(18693..19697)
                     /locus_tag="KB902_001227"
     CDS             complement(18693..19697)
                     /locus_tag="KB902_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808067.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
BASE COUNT         5487 a         4272 c         3517 g         6510 t
ORIGIN      
        1 acatctattt tatcgaagaa acacaaaata tcgagggttc ttatattgaa gtaaaaacac
       61 tctttgtcaa tgaagataaa accaaagcat tggatattta taaaaaatta gcttcaaaaa
      121 aaacgaatag ttttggattg atattaagcg agtataaaat caaagcagaa gagagttatt
      181 tctatcaatt attaaaacgg tggagtaagc ttcccgccga tttttatcga aaaatgcaga
      241 tcatcaacta tcaaccgctt gctgagacac atgcctaaat agaggttgtg aaatcagtgc
      301 tttgagctaa taccgaaggt cagctgatgg aacatcgttt agaagagatt gtgacaactg
      361 cgatttgctt tgagtaataa gaacgctgga cagaaaatag cttctcatat tttctagtct
      421 agtggactta ttgccgagaa gcagcagatg gaacatcgtt taaagaagag atcggtacaa
      481 aataaaaata tctaaattta agttttatct aagtttcgct ttgtaccttt gattcaaatc
      541 aaaggaggcg atcttgatgc tgaaaaaatg gatcacacta ttttttgcca ctccccattc
      601 tagaatcaac ccgtatgatg tagagaatga attcacgttg aaaaaagatt tcccaaataa
      661 ataaaaacca tccgtaaaat catcaatacg attttacgga tggtttttga taacttcttt
      721 gaggataggc tcttgctatt taagaatgta agaaacatta ttgttacata gtatgagagt
      781 ttaatcctct gttatttatg ctatttaaat gcttgattca catcttcgat catcagtttc
      841 attgattcta aaccgccccc gcttaaatac cagacatctg gttcaaggga gatgatctgc
      901 tgatttttac cagcattcgt ttgtgctacc agttcattgg cagaaatatc atctttgctg
      961 tcgtctccac caatagcttt tgttctgtct actacaaata agatatccgg atttttttcc
     1021 agcacatatt cataagaaac actttgaccg tgagtggatg cttcgatttg atcatctgct
     1081 tgttcaaagc caaataaatc atggatgaaa ccgaatctag aaccagatcc gtaggctgat
     1141 aattgccctt cattcacaag tgtgactagt gcttttttgt cagtagcttc tgctttcttt
     1201 ttcgtctgat cgattgcact agataattcc tctaattgag ttttagcttc ttcttgctta
     1261 ccaaagatct cccctaaagc agtgacattt tgctggaaag attcccatgg atttttcgca
     1321 tctaaagaaa ggaaaatggt cggagcaatt tgacttagat ctttttgaaa atctctttgc
     1381 cggccagaaa tgatgatcag gtctggctga agctgattga ttttttctaa gtctggttct
     1441 ttgatcccac ctgctgattc cactttttta taggatgaaa gatactcagg aaggctgctt
     1501 gtagctgctc caactacctt atctccaaca ccaagagcat ccatcgtatc taaagaacca
     1561 ttgtcgaata cgacgacttt ttcaggattc tttggcacct cgatttgatc gccattactg
     1621 tcttttatcg ttaatgccgt ttcagcttgc gtactgcttt tctttgtatc tgcctgactg
     1681 gtgttgtcac tatttccaca tgctgctaaa ccaaatgatg ctagaatcaa gatacctact
     1741 actaattttt tcatctcttc tctcctaatg ttagttttag aaataaagac agaatctgcg
     1801 accttcaatc tcacaaattc gtatgtccat ttcgtacaat tcgtccagta catctttttt
     1861 tatcatttct tgggtcgttc cttgcgtgaa taactgccca tctttcattg caataatttc
     1921 gtctgcataa cttgcagcaa agttgatatc atgaagaaca ataacaattg ttttcccgat
     1981 ttcttgtact aattttttta agatctgcat gatttgaacc gcaaaattca tatctagatt
     2041 gttcaaaggt tcatccagta aaatataatc cgtgtcttgc gctagcacca ttgcaatata
     2101 cgcacgttgg agttgaccgc ctgaaagagt gtcaatcgat tgatccgcta tttcttctaa
     2161 cccaaggtgt tccagtgatt cctgaacgat ttcctcgtct tttgtcgtca attttccttt
     2221 cgtataagga aatcgtccaa attctactaa ttctttcacg gtgatttgga catttatttc
     2281 attcgattgt cgtaggatcg ataatttttt ggctaattca ttggatttcc aagcctttac
     2341 ttcgttatgg tctaaataga tttcacctgt atcttttggt atcaaacgac tgatcatcga
     2401 caacaccgtt gactttccag caccatttgg accgataaaa gcagtcaact tcttttcagg
     2461 aatcgttaac tgtacatctt taaccactga ttttccatgg tacagtttat tgaccttttg
     2521 taaatcaatc ataggatact cttcctttcg cgaatcaatt ttgtgacaaa ataaattcct
     2581 ccgacaaatt caacgacgac actcactgtt gtattccagc cgaaaatctg ctctactgcg
     2641 agctgtcctc ctgtcagaaa cagcatagct accagaaagc ttccgataaa tagctgacca
     2701 tgacgataag tagaaaagac acgataactg atatttgcga caataaaccc taaaaaagta
     2761 actggaccca caagagccgt tgatgtccct gtcaaaagac tgacacaaca taaaatcaaa
     2821 aattcaaaac gatctgtgtc tatcccgagg tttactgctt gttcatttcc gagatggaaa
     2881 acgtctagca catgtcgata tcgaaataac aggtaccagc agccgataat gatcaaagaa
     2941 gcaggcaaaa gatactgact ctggatattg ccaaagcttg caaataatct gccttgaagc
     3001 aaatcatatt cattcggatc catgatgact tgtaaaaagg tactgacact accaaaaagc
     3061 gtacctaaaa tcatccctga catcagtaat aaaaaaagat tcgctctcat ttttttcaaa
     3121 agaaagaaaa ataacaatag actcagcccg accatcagcc caacgttcaa taagaaaaaa
     3181 actgtacctg tctgctgaag catcgtcact cctccgataa agaagaaaag gaacgtttgg
     3241 acaaggacat ataacgactc aagtcccaat actgaaggag tcaaaaactg gttatgcgta
     3301 attgtctgaa agctgattgt ggcactgctg acagctagcg agacaaggat aaatgcaaaa
     3361 attttcttac tcctcaatgc ccatgcaaaa tgccagtttc catatgtatg gatcgtcaag
     3421 tacattcctg taacaaataa aacaagaaca agcataccaa taaaaataga tggctttttt
     3481 ttaagcatat cgtcgccccc ttatcagaag ataaaggaag atagccccac cgatgattcc
     3541 aacgatcaca ctgactggta tttcataagg aaaaatcaac acgcgagcga caagatcgca
     3601 aaatactaag aacaaactac ctgctaaagc agttacgcca attgttttgt gcacttgatc
     3661 tccatatatt ctagagacaa gattcggaat gatcactccg ataaaaggaa tgcttcctac
     3721 catgatcaac atgactgcac tagccaatga tactaagcca atgcctaaaa actgcatctt
     3781 ctggtaatct attcccaaat ttactgcaaa cgattcgccc agaccaatga tcgtaaatcg
     3841 gtaagcaaat agccaaacca agagcaacaa tggaacaaca gcatacaata actcataatt
     3901 tcctcgtatc acagtcgcaa aatttccttg aagccatgaa gtcatatttt gtaccaactg
     3961 gaattgataa gcaaaaaaag tagcaactga accaatgata ttccctaaca tgactccaat
     4021 caacggaagc atcaattgat ttttctgggg gaacaatcgc gtaagggata aaaaaagcaa
     4081 tgttcctgca aaagcaaagc aaaatgctgt caaggatcgg acaatcaagg atgcaccagg
     4141 taggaaaatc atagccacta aaatacctaa acgcgcacta tccatcgtgc ccgcagtcgt
     4201 tggtgaaaca aatttatttt gggtcaaatg ttgcatgatc aacccacaaa tactactggt
     4261 cgctcccaca aggatcaaac aaatcgttcg tggcaaacga gtcactagca agatttgtaa
     4321 gctttgccca tctaactgga gcagttctga caattgtaca ttcgatactc cgatgaacaa
     4381 tgaaatacta cttaaaataa ctaataatgc tactagtcgt ccgtagcgca tccaatccac
     4441 ctttctaatt gagaatgatt ttcattctta ttttaagtga atcgttgaac aaaagcaacc
     4501 gctttttcat atgttttagg tattattggg aatatgctat aatcgtaaga aagacaaaga
     4561 gaagaaggag ggtatttttt atggcacaag atgatgtaaa aagccatttg gataagggac
     4621 tttatggtac acctttagtg aaccctgaag aacagcataa atatttaggg acattcaggg
     4681 aacgctgcta tcttagtatg actgttgctg aaatgatcca accaaaaaac aaagaaaact
     4741 ttttaaaaga actcaaaaaa catccagatg cttccatact cttgaatggg gctctacccc
     4801 tttctgtcca aaaccaatat atccagctag caacgaaaaa caatagccga tttactgtag
     4861 tcaacgatta cgtcactgca aatcctgagg aattcggatt gctcttaaca gcaaaagaag
     4921 cagtaaatga acctgtgatt gatatcgaaa aaaaataccc agaagaaaac tcttcgccag
     4981 ttgaaaaaga aaaaccaaaa aagaaaaaaa gcttctggga tcgtttattt taaaacgaaa
     5041 aaacacataa atttttacat gcaaaaaagc ttttgatcag attgacatca aataggacaa
     5101 tctgtcaaaa gctttttctt ttaaaatact tcaggatata acaatttcaa tacattcatc
     5161 gtcaatcttc tgccttttcc tgcaaaggga taaacatgca tatgcatggc tggattgaaa
     5221 tttgcttcga tgatcccata tgctttttta tcagttgtag gatcgatttc tttatctggt
     5281 ataatcaaat cgataccact aatcttagct cctagtgctt ctaccgcaga aacggcgatt
     5341 tttttgtaag cttcagaaaa ttcatcagtc atatcgatcg aatcaccacc tgtactgata
     5401 tttgagttct cccttagata aacaatttga ttggcttggg gaactgattc gatcgtcaac
     5461 ccttgttctt tcaacatcaa ttgttctaat tcacctaatt ggatcaattc taaaggtgca
     5521 cgatgattcg ttccacgcaa agggtcacta tttttttctt caacaagttc tttcactgtt
     5581 cggataccgt caccaataac attagcaggg actcgcaaca tgatggcttg gacttctccg
     5641 tcgatcacaa agaaacgata ttccgttccc ggcataaatt cttctactaa aaccgaactg
     5701 tcttcacgaa aagcaatggc taaacctgct tgataatctt ccagactagc tccttccttg
     5761 aaaatcgtga tacctaaccc gtaattggtt gatttaggtt tgatcacaaa tgcctgctcg
     5821 gcaaatctcg gataagcttt taccgcttct tccatggatg aaaattctgc gcctcctggt
     5881 acccggaacc cagcttcttt taagactttt ttcgttactg ttttgttttc catgataagt
     5941 gggacgatat agctgtcctt acttgtcatg tttgcatttt tcacatattc tacatggtct
     6001 tggaattgca gacgcaaaaa ttgatccgac tcatctaata ctttgacttg gacacctttt
     6061 tggatggcat cgaacataaa tatctgagta gaaagttcca tttcgcgaaa accggccaac
     6121 tgatagggac gttcatggct ttctttataa tattgatgtc ccaatgccac agcaacttct
     6181 tgctgactcg atagctgtgc ttcttgatag agtttcgctg ctaacgtttg ttcaggatga
     6241 tccatttgag tcaatgcttc ctctactaaa taaagagaat ccaaccaatc caattcaacc
     6301 agcatttgct tcatcccttc aagaatttct ctaccttctt gatgaaattc tgtttgatct
     6361 gatggttgtt ctagtgctac tttgttattt cgagtcgtac cttctgctac ccattggtca
     6421 cagtcttctt tttcttctgt ccataacatg tacatcagga ataattgtaa gaaccgaact
     6481 tgctctggat tgatacccaa tcttgcataa ggattcaaat cgatattccg caattcaata
     6541 taacgaacac ctgttgttgc taaatctgcg actttctttc cgcctcggaa acgaagcggt
     6601 gtataaaatt ctttctcctc cgaaagtttc ccttcttcga tcattcgctc gatatctgct
     6661 aaatactgtt tcatagaagc ataggaaact ttcacatttg gatgattcgt atagcccagc
     6721 gcactgttac gaatactgcg aacaggttct tgcggatgtg attcatctaa aaagtagttc
     6781 ttctcactca ttggtgaagc accgaataaa taagtgatca tccagcgata gcgcataaag
     6841 tttctcgccg ttttcaaata aagttctgtt ttgaattcgg aaaaatcttg aaattcttcc
     6901 tgatggctga acaatgttct tagcaactca tcgccaaatt caaaattgaa atggataccg
     6961 cttaccatct gttttcgctt cccgtattct tttgctaaat aacgtcgata caagacatct
     7021 tcgaaatttt ttaattttgc aataatgatc gcttcgtctt tttccggtaa ggcaggtggc
     7081 atacttaatg gccagatcat ctcttctttc ggtatagaac gagcagtcac atcataaaca
     7141 gcagcgagat actgaaataa ttcgggaata gaatcggtaa caggagtgat catctctgtt
     7201 tgtgtttcgc taaaatctgt ttggatatag gggtgatagg atcgatcgcc aaagattgct
     7261 ggatgatcgg tttttgctag atttcctgca agatcaaccc gctgtccttc ccgttctata
     7321 ccaaatcgag cttggtcgat aaaagggcgc gcattgacat gcaataataa ttgcttaaaa
     7381 ttcatcatta agtgacctcc aattcatatg aatctaatta taatcaaaaa gtctaagaaa
     7441 aagaacgaaa ttgtttgaga accgcttaca aataagtata aaaatgaagg catcaaaaac
     7501 acagctatgt taaaaacaat cattcaaaca aggagctgca acttttgtca cagctcctgc
     7561 tttttagaca tgggttattc ttcttttagt aatcctttga acaatccaac gacaaaatca
     7621 tttggatcaa acggctccaa gtcatcgatt ccttcaccaa gaccgaccaa tttcactggt
     7681 aaatgcaatt cattacggat agcaagtacg ataccgccct ttgctgtacc atctaatttt
     7741 gtcaaaacaa gaccggtcac atctgttgtt tctttgaatt gttttgcttg aaccatcgcg
     7801 ttttgaccag ttgttgcatc tagtacaaga agtgtttctt ggggtgcttc tggtaattcc
     7861 cgctggatta ctcgttttat tttttctaat tcgttcatca agttcacttt attttgcagt
     7921 cggcctgcag tatcaactag taaaacatct gcctgctcta tctttgctct ttccaaagca
     7981 tcgaatacga cagctgctgg atcgccgcct gcattgccac gaacaacttc aacaccagcg
     8041 cgttcgcccc agacaactaa ctggtcgatt gctccagcgc ggaaggtatc tgctgctgcc
     8101 atcaatactt ttttaccttc gtttttgaac tgatgggcaa gtttaccaat acttgttgtt
     8161 ttccctacac cattaacacc gacaaacaaa ataactgtta gtccgtcttc ttggatattt
     8221 agttcattta cttcattgat tccttccgct tcatagagat ccacaagttt ctcgatgatc
     8281 gcattttgga cttctgccga ttttttcgca tttctgagtt tcacttcttg acgtaatgct
     8341 tcggtgattc gtatcgctgt ttcaaaacct acatctgcac cgataagtgt ttcttctaat
     8401 tcttcaaaaa agtcttcatc gactgttcga aaattggcaa acaactcatt catccgttca
     8461 ccaaatgttt tacgcgtctt ttctaaaccc ttgtcgtact tctcctgtac ttcaacttct
     8521 tctgttttct cttcgccagt aaaagcacgc ttgattttat caaaaaatcc catttgactc
     8581 ccccctactc taatacaaat ttttggatca ctttggctac gccattttct tcattgctgg
     8641 ctgtcacgaa atctgctgct tctttgacga aaggcacagc attctccatc gctacgccta
     8701 gtccagcgta ttggatcatc ggtaaatcat tttcttcatc accgattgcc atgatttctt
     8761 cttgtttcaa accaagatct tttgccaata aagaaatacc ataagctttt gtaacacctt
     8821 ttggcataaa ttccaaaagc atacttctcg ttttgatgat ctcatacatt tcatggaatt
     8881 ctgctggtat ttctttgatt ttaggatcta attcttcttg gtcataagcg attactgcct
     8941 tattaagcac aaattcatct gtaatatcgc ttatatccgc tggttggaat tgcagcagct
     9001 tattcaacac attgtacaag gattgcttcc ttggggcact aggcagctgt aaaaccacat
     9061 tgtcagacaa aacatctagt ggcagatcca attgctgagc cagtttgtat aagcgttgga
     9121 tatctgatac ttccatcact ttcttttcca tgatttcacc agtatcattt ttttgtacca
     9181 aaccgccgtt gaaagtgatg ctgtagtcac cttcatctac cagtcctaat tcttgcagat
     9241 aatgcgccat cgcagctaag gggcgtcctg tacatagaac gatcttgacc ccttgctgtt
     9301 ttgcttgtgc taatgcttgt ttattctcat ctgaaatcag cttttgttca tttaataatg
     9361 taccgtccaa atcgattgct actaatttga tcattttcgt tcctacactt tcgtttcgtt
     9421 gattttcgcc tcttcattga tatcttccat ccgtacagaa acgatttttg atacaccgga
     9481 ttcctgcatc gtcactccgt acagtacatc tgctgcgacc atcgttcctt tgcggtgtgt
     9541 gactacgata aattgtgtgt catcttggaa atcgctcaag taacgaccaa aacgtttcac
     9601 gttggcttca tctaacgctg cttctacctc atctaagata caaaacggaa caggacagac
     9661 acggataata gaaaagagca acgcgatggc tgtaagtgct cgttctcctc cagaaagcaa
     9721 acttaaactt tgcagttttt tgccaggagg ttgtacttca atctcaatac ctgttttcag
     9781 caaatcagtt ggttctgtca gtactaattc agctttaccg ccgccaaaca tatttggaaa
     9841 gacaattttg aattcttgac ggatagcttc aaatacttct ttgaatcttg tccgcacttc
     9901 atcatccatc tcatccatcg tttcaaacaa ttggtttttc gctgctaaca gatcatctcg
     9961 ctgtgttgct aagaatgtat gtctttcact gacttgttcg tattgttcga ttgaatttaa
    10021 gtttactggt cccagttttt caatctgttc ttttaaggat gaaacctttg ttctactgtc
    10081 ttcgatatcg gttgtttctt gatagtcttg ggaagctttc tcaaatgtca gctgatattc
    10141 tgactgcaga taggtcaaat gattatctaa aatcatttca gctcggtctt tttggacttc
    10201 taatttggat tgttccgaca gtcgtgcttt ttgctcacga ttacgctctg ccaagactgc
    10261 ttcaagctta tcgatctcct tttgccttct atctcgctgc tctttggctt ttgccaactc
    10321 ggctttcaat gtttctcgct gagcagataa ttcgttaatt tgtttttcca aactttcttc
    10381 tgtgacttca tgatcagaaa agtctgctgt caatgtcgcc aactgctttt ctatcgcttc
    10441 ttgacgttcg gttgcctctg ctttttggac tcgggcaccg cggagctgga tctgcagatg
    10501 attaaactgc tctttcaaga cagcaagatc tgcttgttct tgtgcttttt gactttgtac
    10561 ttgtgctctt ctggcttcca tctggtcgct ttcttgactt aacgatttga tttcttcgtc
    10621 gattttttgt cgttgcgatt caagatctgt ttgtttgtct ttcaattcgt tcgtttgctt
    10681 ttcgtaatct tcgataaact gctgcagttc acgtgtctca aaagttgaga tttgcttttc
    10741 tttttcaaaa cgttcaagtt catttatgat gttttgcagc tgatttgtcg cttcttgttc
    10801 ttcaaaacgt aattgttcgc ctcgtgtacg caaaacttct tgttcttcgg ctaaacgagc
    10861 tgtttcttgt tgcagctcct gaactttttt ttcttgtgct tggagttgtt tatctgcttc
    10921 ttcaaattca ctagtcaact gtttcaattc ttgattttgt acaaacaaac tgccttggtt
    10981 tcctcgttta ttcgctccac ctgtcatgga tcctccggca ttcatcacat caccttctaa
    11041 ggaaaccact cgatattgat agcggatcgt ttgcgcgatt gcattggcac tagttaagtc
    11101 tttggctaaa aggatcgttc ctagcaggtt ttgaaccaca gtttggattt gattgggata
    11161 actgacttgt tcactggcaa tccctataaa cccttctaca gctgctgctt gtgtcaatat
    11221 atgagccggt aattgtcttg gtttgattgt cgtcagtgga aggaatgttg ctcttcctcc
    11281 tctttgctgt ttcaaatacg tgatggcttg ccgagcatct ttttcatttt caacgatgac
    11341 atgctgggct gccccaccta aagctgtttc gatagctaac gtgaaatctg caggaacatc
    11401 gatcagttca gccactgctc cgacaatacc cgaaagctgc tgtttatgct gcaagaccaa
    11461 tcgaacccct tggtaaaaac caaaatagtt ttcttggatt tcttgaaggc ttttcttacg
    11521 agcacgtagc tgctggactt gattcattaa ttgatacatt ttaggctgtt cttttgctaa
    11581 tgcttcttgg aactttttcc cgttttgttg gatcatttct aacttctctt ttgtttcagt
    11641 taaagatgat tttagctgcg cctgcttttg tgtcaattct tctttttgta agatcaatcg
    11701 gtctactgat gcctctactt ccgattgctt ggctaacgtc tgcttacttt ttgctgtttc
    11761 ttgtacatat tgacgttcta gatacttcag ttcgtttcct acagctgctt gctcttgcat
    11821 caaatcaaca tattgatctc ttagttctgc cagtaattct ttcgttgatt tttggtattt
    11881 ttctaattct tgctgtgttt ttatgagact tgcttcagct ttttggattt ctgtttcttt
    11941 ttctgctact tctttcaaca agctttcttg aagcttttca aaatgtttaa cctttttttg
    12001 tgcttctgct aatgaagttt gatattcttg cgagcttttt tgtgtatgct ttgtccgctc
    12061 ctgcaaaaca tctttttgtc cttctgtctg cttcagtttt tccgaaagat ctaataatac
    12121 ttgctgattt ttttcgatca gacgatcggc ttgcgcattt tctttacgct gcttcgccaa
    12181 aatggattct tgttcttgga tcgactcaga tagtttgcct aattctagat tgaatttcgc
    12241 aagctgtgct tgtttgttgt cccaatcttt ttttgctgtc ttgatttcgg caaccatcaa
    12301 agagacatcg gtttgagtca gtgtttcttt tagccgtaaa aactcctttg ctgcctcact
    12361 ctgggcggcc aaaggagtta actgttcttc caattcgtgg atgatgtctt ggacgcggct
    12421 gaggttgtct tctgtttcaa aaagcttctg ttctgctttc tttttccgct gcttgtattt
    12481 caagacacca gctgcttctt caaagatccc acgacggtct tccggtttac tactgaaaat
    12541 cgcttctact tttccttgag aaatgattga gaacgattct tttcctaatc cagagtctaa
    12601 gaacaattct tggatatctt ttaatctgca gctttgttta ttgatgaaaa actcgctttc
    12661 cccagtccgt cgataacggc gggttacact gatctcattg tactccaatg gcagataatg
    12721 atcactattg tctaaaatca ctgtgacttc tgcaatattc agctgcttac gggtatcgga
    12781 accggcaaag atgatatccg gcatttttcc gcctcgcaga cttttagcag attgttctcc
    12841 taatacccag cggatagctt ctgtaatatt gctttttcca ctgccatttg gtccaaccac
    12901 tgctgtgacg ctattttcaa agtcaatgac tgtcttgtct gcaaatgatt taaaaccggc
    12961 tatttcaatt cgtttcaaat acaaagcttt ccctcactta cttttacagt gctgccaatg
    13021 cattttccgc cgcagcttgt tctgctaatt ttttcgattt tccttgtcca gtgccaatca
    13081 attgatcatc tacataaact tcgatccaaa atactcgttc atgagctgga ccttcttcat
    13141 tgatcaatcg gtattcgatt gatacatcac ctgatttttg caagacttct tgtagttttg
    13201 ttttatgatc catctcatgt gaaaaagcac ctgctttgac tttaggaaaa atcacttttt
    13261 cgatgaatgc atgggtcgtg tcgaatccct ggtcaagata taacgcgcct aaaaaagctt
    13321 cgaataggtc gcaaagcaat gctggtcgcg tacgtcctcc tgaattctct tctcccttgc
    13381 ccaacaaaac atattgatca aagtgacatt ctttggcaaa tttcgacaag ctgtcttcgc
    13441 gaacgatcgc agctcgtgtt tttgtcaatt ttccttctgg caaatgagga tataaacgga
    13501 ataaatactg agaaaccatc agttctaaaa cggcatctcc taaaaattca agtcgctcat
    13561 tatccgataa ttgcagattg cgatgctcat tcacatagga tgaatgggta aaagcttgtt
    13621 caagcaaatt tagatcgtga aaaacgatgt tatagttttc ttttagttct tttgtcagct
    13681 ggttgtccat tttccacatt ccttttatgg atattttttc gatacttcct tattatactg
    13741 gttttttgtc aaatttgaaa tggttcggtc aaaaggtaag taaagcttta ataatcctag
    13801 tgattgacga gaagttgtga aaaattcgtt tagtttcgag tatgaagaaa aaattttgtg
    13861 aaaatggctt tccatatttt tgcataaatt tgacttaata ccgagaaact ggactttgaa
    13921 caccgtttat tggagaagtc atgaaatcag cgccttgacc tgaatattag agaaataaac
    13981 agaaaaatat caaaaaaccg aaaaaggaca tcgccctttt tcggtcattt ttagtgatta
    14041 tgaacgtgaa tctgctgtaa cagaaacatt tgcccatggg tttggtacat cataagacca
    14101 atcccagtct ttgacacggt cgttgactgg caatacttca ttacggaaca acgttggaat
    14161 cgcaaatgct tcttcaaatg catattgttg ccatttttga tatgcttctt tttggtactc
    14221 ttcatcaaat gctttgcttg aactgatatc gttgatcaat tttgtatttt cttctgattc
    14281 ataacgagtg tagttgaacg cagcatttgg tccccatagt ccacttggat ttggatcagt
    14341 tcctgtattc caagcagctt ggtaaacatc aatttcagga tcatcgtttt ctaatttatc
    14401 atagaaagaa ttgaattcga tcagacgacc tgttgtgtat tggacatcca aaccgatttc
    14461 tttccactgt tggatatagt aatctgccaa tggttgcgct gtttccccac cggacatcga
    14521 agcaaagttg attgttagtt tatttccatc tttgtcttct cttaaaccat cgtcatccac
    14581 atctttgtag ccagcatcat ctaatagttt tttcgctttg tctagatctt gtgtgaatcc
    14641 tttcatctca tcatcatggt atgactggaa tactggagga atcaatgaag tcgcattgct
    14701 tctcaaacct gcatagaaac gctcacctac tgcattatta tctaatgcat agcccattgc
    14761 ttgacgtaat gatttatcag ccatttttga atctggattg tattccacac tctttgtatc
    14821 tgcattccat ttacctaact tgaatcctag ataagtataa gaagtttgtt cacggcctaa
    14881 gtttgtatag ccagcaattt ctttataggt atcgtaagta tctgttggca tttggaaaat
    14941 catatcatat aatttagagt tcaatgcttc agttgcactt gccatcggta cagatttcat
    15001 cgtgatcttt ttcaatttag gcgtaccatt ccagtagtgc tcgtttggca agtattctac
    15061 tgattctcct gcaacgatat tactcatgta ataagggcca aaagtcactg gatttttacg
    15121 tacttgatcg cttgattcca tatctttgat tgctacacct tctaacgtat gttttggtgc
    15181 tgcatatgac caaataccac cacccgattg aagcatgctt gggtttactt ctttatattc
    15241 gatttcaact gttttgtcgt ctattttttt gattccggag attgtgtcgg cacttccatc
    15301 atgatattct tccataccta cgatgttacg gaaagtgtcg tcataacgga taccagtgta
    15361 atctttattc ccaatgattt cgtaagggaa aatcacatcg tccgccgtta catcttcacc
    15421 atctgaccat ttgacgttgt cttttacttt gattgtcgct tttttcgtat cttcatctag
    15481 atcaagcgtt gcagctccgt cgtctgtgat tctgaaatcg tcatcgtttg caaatagcgg
    15541 ttcatgagaa ggagccataa aagctgcatc atatgaatct tggtaaaact cccactggaa
    15601 caatccttta aactgactgt ccgttgcgac cgcagcttct aattcgccgt cttcgattgc
    15661 atcatcatta ttttttgttg caattggaaa agttaattcc tctttgttat tgccgttgcc
    15721 tccagagttg tttccagagg tatctgtacc tccgcccccg catgctgcaa gaacgacagc
    15781 agacatcagc gctgcaaatc caaaaatcgt tttcttcatt cctatttccc ccttcgcttc
    15841 tatactagcc taaccgttgg cgcgcatctg cagaacgctt gaatgcttgt ccaacataat
    15901 tgatactcaa catcaaaact aaaataagga ttgatgcggg taaccagatc cattgccgat
    15961 tcactaagac ttctccgtta cttgcataac cgatcaatgt acctaaacta ggtacatttg
    16021 ccggcaagcc gaaacctaag aaagtcaaag ttgtctcgat accgatgttt gccgcaaagt
    16081 tcatcgtcaa attagtaatg attaatgaac ttagattcgg catgatttcg cggaacatga
    16141 ttttaaaatc attggttccc attgtttttg aggcactgac ataatctctt cttgcttcag
    16201 ataatgtctt gcttcggaat aatcgggctt tagctaccca ataaaatgca ctcatgatga
    16261 atataaagga ccagacattg tatctggaaa taatcgatac gaagacgata atgatcagca
    16321 tgatcggtag aatcatgata aaatcaacga tccgcatcaa gatgttgtca atgatccctc
    16381 cgtagtagcc agagatgatc cctaatccaa ccccgatgat cgaagtaagg atcgtgatcg
    16441 caaatccgat cgtaacagag tttctagcac ctatgatcaa ttgtcctaat acatcacgtc
    16501 cgccttcatc tgctcccaga atgaactttt gtccttgtgt cgaaactgtt cctggtgcag
    16561 cgtatttgtc gaagatacta acatacatca ctttgtcttg atcggtcagc atcgcaccga
    16621 taaagatcac taataataaa accactagca aacctaatga aaaaatagca attttatctt
    16681 ttttaaattc tcgagcaatc attcgtatcc ccataggagg aatactttct tgaactgctg
    16741 tattgttttt ttcactcatc gatccattct cctttctgat tggttttatt gaatccgaat
    16801 acgcgggtca acgatactca tgatgatatc tgaaagtaat gtccccacta gcgtcgcgat
    16861 tcctaaaatc aatactaagg atgtgatcac ggtatagtcc cgttggccga tggaatcaat
    16921 aaatagtttt ccgactcccg gataaccaaa aatcttttcg ataactacag aaccagcaat
    16981 caacgaagtg atttcatacc ccatttgaga agccatcggc aacgctgcat ttcggaaaat
    17041 atgtcgactg aatactttat tcgtcggtac ccctttggaa cgggctgttc tgacaaaatc
    17101 gagcgatttc gaatcgatta cttcacttcg cagatattgg attgtgacgg cagtcgccaa
    17161 aaatgcttgg gtaattgatg gtaacagaat atatttcaaa cggtctatcc attgagtgat
    17221 aaatccacct tgcaaaccta gtgtttgtga tccacttgtt gggaaccagc ctaaacgata
    17281 accaaaaaca aatagcatga tcaagccgaa gataaataaa ggaacagcaa aactaaagaa
    17341 gttgtagatt acgacaatct tatccaagat tgaattttga taccggccag caagcatccc
    17401 cagaggcaca gcaatcaaat aagtaaggac aactgtcaag atcgatagat ataaagtgtt
    17461 gatgatccgt tcgccgatca agtcagcaac agagcgtttg tataagaaac tttgaccaaa
    17521 atcgccttgc aaagcatttc cgatccaacg gaagtactgg acataccatg ggtcattcaa
    17581 gccagctgct tgtcgcatct gttcgatcac tgccggatcc tgatttggat tgatcaaacc
    17641 ggtaaatgga tcccccggca tcgcttgggc taataagaag atcagaacac ttaaaataat
    17701 aacttgcggg atcatcaata aaacacgtcg cagaatcgtt ttccacatta gcttgcacct
    17761 ccatctttca acgccacttt gtgtgtagtt gtgatcgtac gcaaatcgta gactcgacca
    17821 gtcgcatcat agtattcttt ttggttttgg atatactctt gttctactct tcgtcgattt
    17881 tctttgtggc tttccctatt ttctacatcg atttgcggaa tagctgaaag cagacgtttc
    17941 gtatagatat gtcgcgggtc attataaatg tcttctcttg taccgatttc tacaaatcga
    18001 cctttgtaca taattgcgat attgtcgcac atgtgtttta ctacacctaa atcatgtgaa
    18061 atgaataaat agctgaggcc gtattcttgc tggattcgtt tcatgaaatt caatacttgc
    18121 gcttgaacag atagatccag agcagataca ggttcatcgg ctacgatcag ttttggattg
    18181 gtagcaacag cacgggctac tcctagacgt tgacgttgtc cgcctgaaaa ttcatgagga
    18241 tatttatata gcgcatcttc cggcatccca acgatatcta gcagtccttt tacctttttc
    18301 ttttcttctt gatcgcttaa ccgttcaaaa tttcggatgg gttcagcaat gatatccaac
    18361 actcgctttt taggattcaa actggacatt gaatcttgga agatcatctg cacatccttg
    18421 ttataaccca tttttttgcg gttgcttcgc ttcgttacat cttttccttc atacatgatt
    18481 tgtccggctg tcaccttttc taatcccaca acggcttttc ccgtagtaga ttttccagag
    18541 ccagactctc ccactaaacc atatgtcttt cctttttcga taataaaatc cacaccatct
    18601 acagcatata catgatccgt tactcgattg aagaatccac tgcgaatagg gtaatgaact
    18661 ttcaggtctt tgattgtgat taattctgtc atctacacct ctcctttttc gtctctaaag
    18721 tggaaatgct tatagcagga gcaacgtacc aagtggttcg gtgcgacttc atgaaggata
    18781 ggctcttctt catgatcgct tgctggtatc catggaatac gtggtgcaaa ccgacaacct
    18841 ttacgaggca tgtttttcag agaaggaacg acaccttcga tcacatggag ttctgcatca
    18901 tgatttcctt cttgtggtat agagttcagt aaagagcgtg tataaggatg cttaggatga
    18961 tcaaacagtt cttttacacc tgctacttca acgaactgtc cgccatacat cactgccact
    19021 cgatcagcca tttctgctac gactcctaag tcatgagtga tcaagatgat ccctgttttt
    19081 gtttcttcct gaaggtcttt cagtaaatca agaatctgtg cttggatggt tacatctagg
    19141 gctgtcgtcg gttcatctgc aatgacgatt ggaggtttgc aggcgattgc gattgcgatg
    19201 atgacacgtt gtctcatacc gcctgatagt tcatggggat attggcgtcc aactctcgca
    19261 ggattaggaa tccctacttg ttctagcaat tctagtgcac gagcttgacg ctgttctgca
    19321 ttcatctttg tgtgatagga aagtccttct ttgatctggt cttcgattct catgagagga
    19381 tttaatgcag acaacggatc ttggaaaatc attccgatat catttccgcg gattttatta
    19441 tagagcgttt cgttcaggtc gattaaattc agatcgttat ataaaatctc acctgtaatt
    19501 tttgtgttat taggatcaag taatcccata atcgtagtag ccaaggtact tttcccgcac
    19561 ccagattccc caacgattgc taaaatctcg tttttgtcta aagtaaatga aacgtcatct
    19621 actgcatcgt aatagtcatc tttgagtcgg aatcctgtat gtaggttctg aacttctaat
    19681 aattggttat cggacaatcg aatacccctc tctgcttcct aaatggaagt ttttcttaat
    19741 aaaaaaggac attacacaga ataaagcgtt ttataacaaa ggttat
//
LOCUS       DADVXB010000045        19639 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.045, whole genome shotgun sequence.
ACCESSION   DADVXB010000045 DADVXB010000000
VERSION     DADVXB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.045"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            123..1382
                     /locus_tag="KB902_001228"
     CDS             123..1382
                     /locus_tag="KB902_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBB6808068.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGDFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(1470..2417)
                     /locus_tag="KB902_001229"
     CDS             complement(1470..2417)
                     /locus_tag="KB902_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6808069.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDHRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            2811..4103
                     /locus_tag="KB902_001230"
     CDS             2811..4103
                     /locus_tag="KB902_001230"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBB6808070.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            4118..5887
                     /gene="aspS"
                     /locus_tag="KB902_001231"
     CDS             4118..5887
                     /gene="aspS"
                     /locus_tag="KB902_001231"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBB6808071.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            5996..6871
                     /locus_tag="KB902_001232"
     CDS             5996..6871
                     /locus_tag="KB902_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6808072.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            7137..9020
                     /locus_tag="KB902_001233"
     CDS             7137..9020
                     /locus_tag="KB902_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6808073.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(9095..9379)
                     /locus_tag="KB902_001234"
     CDS             complement(9095..9379)
                     /locus_tag="KB902_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6808074.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(9369..10103)
                     /locus_tag="KB902_001235"
     CDS             complement(9369..10103)
                     /locus_tag="KB902_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBB6808075.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            10232..10855
                     /locus_tag="KB902_001236"
     CDS             10232..10855
                     /locus_tag="KB902_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBB6808076.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            11047..12168
                     /locus_tag="KB902_001237"
     CDS             11047..12168
                     /locus_tag="KB902_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBB6808077.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            12175..15303
                     /locus_tag="KB902_001238"
     CDS             12175..15303
                     /locus_tag="KB902_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBB6808078.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            15322..18516
                     /locus_tag="KB902_001239"
     CDS             15322..18516
                     /locus_tag="KB902_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBB6808079.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(18662..19369)
                     /locus_tag="KB902_001240"
     CDS             complement(18662..19369)
                     /locus_tag="KB902_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6808080.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT         6547 a         3470 c         4156 g         5466 t
ORIGIN      
        1 tagactgaaa aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca
       61 gcagtcggaa aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga
      121 agatgaaaga agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa
      181 aaggatacaa catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa
      241 agattttcaa taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg
      301 atccaaggaa tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg
      361 gtcaaggtgg agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta
      421 tggatctaat gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga
      481 cacaagcact tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt
      541 tctttacatc tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg
      601 tcgaaaaatt agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg
      661 atcacataaa aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg
      721 aagaagctcg acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca
      781 atgccacaga tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga
      841 acatcatccg tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt
      901 tcagtagacc agatttgtat cagcaattaa aaaatgactt ttcgacgttg caagatccgt
      961 ttattcaaga aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga
     1021 aagaagtaga agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat
     1081 atggaacaga ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt
     1141 atgtagggaa agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg
     1201 ggggagattt tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac
     1261 gtgtgttttc cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga
     1321 cgattccatt caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt
     1381 agattagcat aaacttatcg aaaaaaggaa gatcaaacag tgctgatctt ccttttttca
     1441 tattactata aattgataag gtcaattgat caaaatccac gaaatgcttc atcaatggtt
     1501 tgataatctt cattggataa atgcaaatct aaagcttgga cattgtcaga tacttgctct
     1561 ggacgcttag ctccaggtat aactacagac actcgtggat tcttcatgta ccaagctaaa
     1621 acaagttgcg caggagtggc ttggtatctt ttagcaatgg ggcgaagtac atcgacagcg
     1681 gttaaaattt ctctgaaacg ttctccttgg aaatctggat ttctttttcg atgatctcct
     1741 tcaccaaatt gtttttcctc accaagttca tattttcctg tcagcaaacc ggaagcaaga
     1801 ggaaaatagg gaacaaaact gattttgttt ttttcaagat aagggaataa ttctttttca
     1861 gcctgccgat ggatcaaact gtatttatct tctactacat cgacatatcc atctgcattc
     1921 gcttctttca attgttctaa cgtgaagttt gacacaccga ctgctcggat ttttcctgct
     1981 tcttttaatt catgcaatgt agcaactgat tcattttttg gtgtgctttc atccggaaag
     2041 tggatataaa aaatgtcgat gtaatcagtt tgcagacgtt ttagtgcatc ttccaccgat
     2101 tgtttgagaa actcaggaga attatcaaat gttcgccctt tatttggtac atgagcagct
     2161 tttgtagcga tgacgacacg tgagcgatca tattcttttt ccttcagtac ctcgccaatc
     2221 agttcttcgg aacggccgtt tccgtaagca taagcggtat cgatcaaatt gatcccgcta
     2281 ttcaaagctg tacgaactac ttgttttcct gtctcatctt ccaaaccgtc aaaaagatta
     2341 tgtcctccaa cggcatttgc tcctaatcca agctgttctg cgtagacttg tgaatgtccg
     2401 attcttattt ctgccatagc tgattcctcc tttttgtcta gtctaaaaca aaataccaaa
     2461 aagctgaact aaaacgtttt tgtgagggga aatagtcaga tatctcttga ctttgagact
     2521 ggtttttagt aggttataag taatatcgaa tgtcaatgaa agagcgagta agtttttgaa
     2581 actttacaag agaggatcat cgaggctgaa aatgatctaa agtttcatta gcctaaagac
     2641 actctggaga tggacgagtg aaaagccgtc ccgcgtacga gcgttattcg taagaggaaa
     2701 gagaaatctt tcaaaattag gtggtaccgt gtatgaattt cattcaccct tgttcatgat
     2761 gaacaagggt gattttttta tttacatagc taagaaaggg agagaaaact atgagtttcc
     2821 aaagaccaaa aggaacaaat gatattttgc caggcgaatc agaaaaatgg cagtttgtcg
     2881 aagaaacagc acgtttatta ttcagagatt atcagtataa tgaaatgcgt acaccgattt
     2941 ttgaacacta tgaagtgata tcccgaagtg taggggatac aacggatatc gtttcaaaag
     3001 agatgtatga tttttatgac aaaggggaac gccatgtgac gcttcgacca gaaggtacag
     3061 caccaatcgt tcgttctttt gttgagcata aattgttcgg cccagagtat gcgaaaccgt
     3121 tcaaaacttt ttatatggga ccaatgtttc gctacgaacg ccctcaaaaa ggacggttac
     3181 gtcaattcca tcaaatcgga gtagaagcat ttggatcaga aaaccctgca actgatgtgg
     3241 agagcatggt gatggcactt gatttcttca aacagttggg gatcacgcaa atccggctag
     3301 tcatcaattc attaggtgat aaagaaacgc gtcaagccta tcgtcaagca ttgatcgact
     3361 atcttttacc ttttgaatca gagctgagtg aagactctaa acgccgcctt catgaaaatc
     3421 cattacgcgt attggacagt aaagacaaac gagatcaaaa atttgtggca gaagctccat
     3481 ctatcttaga ttatctaagc gagcctgctc aaaaacattt tgataccgtt gtttccatgc
     3541 tggatgcatt ggctgttcct tatgaaatcg acagtaatat ggttcgcgga ctagattatt
     3601 acacacatac gatttttgaa atcatgagtg acgcaccaaa aatgggggca caagcaacga
     3661 tttgcgcagg cggacgttat gacaatctag tggaagaact aggtggtcct tcaacacctg
     3721 gcttcggatt tgcaatgggt atcgagcgat tactcttgac tatggaggca gaggaagtag
     3781 ttatccctgc atttaatgag ttggatgctt acgtggtcgc actcggagac gaaacaaata
     3841 tcgaagcatt gaaagtggtc caagcgattc gaaactttgg tttttcagct gaccgcgact
     3901 tcatgaaccg taaagcaaaa gcgcaattta agacagcaga taaagcgaat gccaaattag
     3961 tattggtgat cggtgaagat gagcttgcta gtcaaacgat taatgtcaaa gcaatggcaa
     4021 gccgaaaaga aaaaagtttt ccattagaag agatatatga acattttgat gaagtctatg
     4081 atgaaatgac tttattcgag taggaggaaa aaaataaatg gcacaaagaa cgatctattg
     4141 cggattagtt tccgaacaac aattagaaca aacagttaca ttaaaaggat gggtacaaaa
     4201 aagacgagac cttgggggag taatctttat cgacctacgt gatcgtgaag gaatcgttca
     4261 aatcgtcttt aatcctgaaa tcaacaaaga agcatgggaa atcgcggata aatgtcgcag
     4321 tgaatacgtg atcgaagtga ctggggaagt tagaagacgc ggagaaaatg cagtaaatcc
     4381 taaaatggcc actggtgaat tcgaagtgat tgcaagtgaa atcgtgattt tgaatcaagc
     4441 aaaaaccccg ccatttcaaa ttgaagatga tcaagcaatc agtgacgaaa tacgtttgaa
     4501 atatcgttat ttggatctgc gtcgtccaaa aatgactaaa aacatcaaat taagaaatgc
     4561 gacaacaaaa gcgattcgtc attatttaga tgataatgac tttctcgata tcgaaacacc
     4621 ttacctaggg aaatctacac cagaaggcgc aagagactac ctagttcctt cacgtgtcca
     4681 tgctggacat ttctatgcgt tgccgcaatc tcctcaattg tttaaacaat tgctgatgaa
     4741 tgctggattc gaccgttatt atcaaatcgt tcgttgtttc cgcgatgaag atttacgtgg
     4801 agaccgtcag cctgaattta cgcaagtaga tattgaaaca acgttcttaa cagcagaaga
     4861 aatccaaact tacacagagg gattgattgc gaaggtaatg aaagaagttc gcggtatcga
     4921 agtcacattg ccatttcctc gtatgaccta tgatgaagca atggctcgct acggcagcga
     4981 caaaccggat acacgttttg atatggaatt gatcgatcta agcgatacag tcaaagaagt
     5041 agaattcaaa gtcttccaaa tggctcttga aaacggcggt gtcgtgaaag cattgaatgc
     5101 taaaggcgct gcagatcgct actcacgaaa agacatggat cagttaggtc aatatgtagg
     5161 acaattcgga gctaaggggc ttgcatggct gaaagtagaa gaagacggat tgaaaggtcc
     5221 aattgctaaa ttcatgggag aagcaacaga agcaatcatt aaagcaacag atgcaaaacc
     5281 aggtgacttg ctgatgtttg gcgcagataa aagtgaaatc gtcgctgctg cattaggtgc
     5341 tatccggaca cgtttaggaa aagaattagg actaattgat gaatcgaaat tcaatttctt
     5401 atgggtaact gattggccac aatttgaatt ttcagaagaa gaaggtcgat atgtctctgc
     5461 tcaccatcca ttcacgatgc caaaagaaga agatatcccg ttattggctg aagaccctgc
     5521 aaaagtctat gcagaagctt atgatatcgt cttgaacggt tatgaactag gcggaggttc
     5581 tatccgtatt catactcgtg agcttcaaga aaaagtacta gaaactctag gctttacaaa
     5641 agaacaaatg gaagaacaat ttggtttctt gttaacagct ttagattacg gattccctcc
     5701 acatggcggt attgcattag gattggaccg ttttgcaatg ttattagccg gagaagataa
     5761 tattcgtgaa gtcattgcct ttcctaaaaa cggaaaagca gcagatgtga tgagtgatgc
     5821 accaagtatg gtttcgcctt tacaattgtt cgaattgaat attgatgtaa cgaatataga
     5881 agaatagccg ataaaaaggt aaaaaggatt tgtcgaatac gcttcttttg acaaccttga
     5941 tttaattgaa aaacacttta taatgaagcc ataacatata aagcggggct tttccatgaa
     6001 aaaaacattc gaaaattggg cttatcatga ttacacgacc aagctttcgg tatctatcgt
     6061 ttatgcgttg atcgcatcag tcgcattgaa tttcttttat cagccaggac atatttattc
     6121 aagtggtatt actggtctag ctcagatttt gacgactttg tcaaaatcac tgataggatt
     6181 cgaagtaccg gtatcaacaa ctttgtattt actgaatata cctttgtttg tattggcgtg
     6241 gttaaaaatc gggaagaagt ttacaatttt cacttttatc acagtcactt tgacctccct
     6301 ttgtatccat attttaccgg aaacagtcct atctaccgat ccaatcatct gtgcgttgtt
     6361 tgggggggct gtgatgggac taggtattgg gctagcgttg agaaacggcc tatcatcggg
     6421 cggtctagat atcgtgagta tcacgattcg taaaaaaaca ggaaagtcga ttggttctat
     6481 ttcgatctac ttcaatgcat tgatcgtttt tgttgccgga attctatttg gctggcaata
     6541 tatgttttac agtacgttgt ctattttcgt cagtggaaaa gtaactgatg tcgtttatac
     6601 taaacaaaag aagatgcagg taatgatcgt aacgaaacat ccagaaaaag tagtaaatga
     6661 aatccaaaac tgtatgcgta gagggatcac gatcatcaat gaagcagaag gtgcttataa
     6721 gcatgataag cagacagtat tgatgacgat cgttacacga tacgaactgc ctctacttag
     6781 agaagcaatg aaagcttctg atccacaagc ttttgtaagt attgcagaaa acgtccagat
     6841 acttggtcgt ttctatgagg atggcattta gatcgagttt gacaaaaatt catgaaatac
     6901 tgctgtagac agacgttcgt ttgtctgcag tttttttcta ccatagtaga atcagcaaag
     6961 aaaaactgct tttttatttg aaattttctt aaagttgaaa aaaagcatgt ttattttttt
     7021 aaatttatgg gatgatagaa aaaaatagta gagaaaggac acgattctac ttgctatttt
     7081 cacttaatac ccgtatatta cgaatgaaaa aagtttatga aaagttggaa tattgaatgg
     7141 aaaaacaaaa aaggttaaaa aacagccgct acatcactgg gtttgatggg ctccgttcat
     7201 tagctgtggt gggtgttatc ttctatcacc ttctgccaac tagtatgaaa ggcggctatt
     7261 tgggcgttcc gatttttttc gtcgtatctg gttatttgat cacggatctg ctgcggcagg
     7321 aatgggaaca aaatggaaaa atcaatattt ggcaatttta tgtcagaaga atgaagagac
     7381 tctatccggc acttgttttt atgcttgtga cagcttcggc ttatatcact ttgtttcagc
     7441 gagggctgtt aaacaatctt cgaggagttg tggtcagcag cttactgtat gtcaacaact
     7501 ggtggcaaat caataacggt ttatcttatt tcgatcgatt tgctaatgag tcaccgttta
     7561 cgcatatctg gtctttagca gtagaaggtc aaaactattt ggtttggccg atcttgtttg
     7621 tattgttgat ggtatttgtt cgtaaaagaa aatggatctt ttatactgtg ttaggtacat
     7681 ccttcctctc cgccatcttg atgatgatct tgtatacacc aggaggcgat ccaacccgtg
     7741 tttattacgg taccgacact cgtctgtttt ctatatggtt gggaagtgcg cttgcgtttg
     7801 tttggccaag tacgcgttta aagaaaaaca tcccgaaaca agcgaaaaat attctgaata
     7861 tcgctggagg aatctcgctt ttggcactga ttctttgctt cttcttttta gatgatcatt
     7921 acaatttcat ctattacgga ggaatgctcc tagtgagtct gttatgcgta gtgctagttg
     7981 cagtgacagc acaccccgga gcaagtttga atcgatggct gacaaatcca gtatttactt
     8041 ggattggcaa acgaagctat ggcatttatc tgtatcagtt tccagttatg attttttatg
     8101 aagcaaaggt gactgatatt gccgatcatg ttttgttgca tactttagtg gaaatcacat
     8161 tgattctaat catcagtgaa ctttcttatc gatatgtgga gcgtccgcta gcacgttttg
     8221 attatggtcg tacattccaa gtgatgaaag gatggttcag caaaccgatc atcagtaaga
     8281 gcaaaccatg ggttgttcca ggcacattac ttgtagcaat tgcactcgtt ggtttcgtta
     8341 cggcaccgaa aaacgctgta acagccgatc aaaaacaact gcaggcaaaa atcgctgaaa
     8401 gtaaaaaatt agcagaagaa accagaaaca attcagaaaa caccactagt tcggttgacc
     8461 aagcgatcct tgataagtac gagttgtcca aggcacaagg gaataaggca caaaaattag
     8521 aactaacggc atttggtgat tcagttatgt tggatgctgc aacggatcta caagaacttt
     8581 atccaaaagt agtggtagat ggagatgtcg gacgacaatt atatgccagt gtaccgtaca
     8641 ttgaaaaatt aaaggaacaa gatttgttga aagacactgt tctgatcgga ctaggaacga
     8701 atggctcatt ctcggaagct cagtttgata gtgtgatgga tgcaatcggt gatcgaaaag
     8761 tatactgggt caatgtccga gtaccgacga agcgctggca aaatgacgtg aatgcgatgc
     8821 ttgaacagat gacgaaaaaa tacgacaata tgacgctgat tgattggtac agctacagta
     8881 atgaccatag tgactggttt tatgatgatc aagtccatcc aaatcctgaa gggatgacac
     8941 attacattca cttagtcagc gaagccttgc taggaggaag ttcaagtacg aacagcagtg
     9001 agacaaacgt gacagaatga tagctacaaa aaacttcagg caaaaacatt tgtttttgcc
     9061 tgaagttttt ttatatttac cgtgttttta acattcatat agattcagga agcaaaacgg
     9121 ttgagtgtgt ctgtaaataa cgttcttttt gttttcgggt gagttttttg aatgcagctt
     9181 ctgcttttgt tgcttcgctt cttgaagaaa atacttctgc atggatcatc ttaacaggtc
     9241 ttcttttttg aagacgagta tatttagcac cagtaccatt gttatgttcc tctaatcgtc
     9301 tagaaagatc ggttgtatat ccaccataaa atgtctgatc tttacagaat aatacgtaaa
     9361 aataatgttc atttgccata gagcatctca cgaatctctg cagtgtattc tccatccata
     9421 ttgtaagtga tcaatggtgg agcgactttg aatccgtcta atttgccttc tttgattcct
     9481 tcaactaaca aaatatttgc ctcttttcca ggttttgggt aaacaaattg gatcctttta
     9541 ggtgcaattc gatagtcttc catgacctga atgatttcta agaaccgatc aggacgatgg
     9601 accatagtaa agcgtccatt tgtttttagt agcttacttg aaatatcgat cacttcttct
     9661 aacgtcgtat gaatctcatg acgggcgatt gccaggtgtt tattagggtt cgttttattt
     9721 gttggcagcc ctttgaaata aggtggatta cagacgacta agtcacaaga attatgtcga
     9781 acgacagata agctgtcttt cagatcgatg gtgtggacag tcatttgttc atttaaatgg
     9841 ttaagcgcga tactacgtct tgccatgtct gctagacgag gttgaagttc gatagcgtcg
     9901 atagccgcct gggttcgttt acttaaaaaa agtccaactg cgccatttcc tgcacaaagg
     9961 tcaacaatct tccctttttt aggtacacgg gaaaagtgag caagcagcac agcatctaaa
    10021 gaaaaagaaa acactttgga actttggata atcttgatat cttctgcgta taattggtcg
    10081 attcgttcgt cttcgtgaag catggattcc ctccaaaatg aaaaaaatag tcgtctgtat
    10141 tatactattt ttattaaaaa gaaccaaggt ggcttgtcaa acctctattt tttatgcata
    10201 ctatgaccat aagaagggaa aggaagagac tatgttttat cgatttatgc gcggggtagt
    10261 tcgagtacta ttagccttag ttaatggaaa tgcccgctat gagaataaag aagttttacc
    10321 gcaagatgag aattacatac tagttgctcc ccatcgtact tggtgggacc cattatatct
    10381 ggcggtagct gcagcaccca aggaattcag ctttatggca aaagaagaac tgttcaaaaa
    10441 tccagttctg cgatttatat taactcgatc caatgctttt ccagttaaaa gagaaaatcc
    10501 aggaccaagc gtcattaaaa cacctgtaaa gattttgaaa tcgacaaatt tgagtttgat
    10561 catgtttccc agtgggacaa gacatgctac agaacttaaa ggcggaatgg cattgatttc
    10621 cagaatgtct aaagcgaaaa tcgtgccagc tgtatatcaa ggtccgttga cacttgggga
    10681 tctgttcaag cgtcagagag tgacagtgcg tttcggcgaa ccaatcgact tatcagatat
    10741 caagaaaacg gataaagaag gtatggcgga gatcgaacga cgaacacaag cagcttttga
    10801 caaattggac aaagaagtga accctgattt caaatatgaa gtcaaaaaaa aataaaatga
    10861 taagtttatg cgtgggcggt cttttgaatc tactgtcctg ttcagttcag actttttcaa
    10921 tgaaaacgag ggagagacgt caagtctgcc ctctttttgc gttccaatat gtaaaataga
    10981 agacaggtgt catgtaatgg atcaaagtgt tataataatt agaaggacat tttttgaggt
    11041 gattgaatgc gttttttaca tacagccgat tggcatatcg gaaaaaaact acaaggttat
    11101 gacttgattg aagaccagcg tcatgtacta tcttctatac tagatatcgc gaaagaagaa
    11161 aaagtagagg caatcgtgat tgccggagac ttatatgata ggagtgtccc agctgttgat
    11221 gccgtagaat tatacaatga attgatggtc gattggaatt taaaggaaaa gatcccgatt
    11281 tttgctatat caggaaatca cgatagcagt acgagacttt cagcgggtac gccatggttc
    11341 agttattcga actatttttt gcgaacacag ctagcagaag catttgaacc agtcgagttt
    11401 aaaaacgtac aatttttctt tcttccttac tttgaaccaa ttgcagcgag attatatttt
    11461 gaagatgaca atatccgaac gatcaagcaa gcggtagcca aggtgataga taaaatgcag
    11521 gagctatttg attcagaaaa aaaacaagta ttgattagcc atttttttgt aatgggaagt
    11581 gtaaaatctg attcggaaac gaaaatcgaa gtaggcgggt tggattcgat ccctggtgaa
    11641 ctacttacac cgtttgatta tgtagcacta ggacatttgc ataatcaagc tgctttgaga
    11701 caggataatg ctcgctatag cggttcccca ttgaaattct ctttatctga gatcaaccaa
    11761 aaaaaaggcg tatggatcgt tgacctgaca acaggcctgg agttgaattt tagggagatc
    11821 gaacccctgc atgatattga agaaataaca gcgagtttca aagaattgct ggatcctgcc
    11881 ttttatcagt ccgtcaatcg ggagaattac atctatatct atctcactga tagaacgatc
    11941 atcccgaata tgatgaacca gcttcggcaa atatatcctc gtattttggg gattgaacgg
    12001 gcaaacggtc gagcagaaca aacaaagcgc aaacgaaaag tactagaaat gaaagatcct
    12061 caaaaattag cagaagcatt ttttagtgaa atgacggaag agcagctaac tgcaaaccaa
    12121 gaaaaatggc tcggagaaac gttgcaagaa atcatggaaa tggaatgatc aagaatgaaa
    12181 ccgaaaaaat tacaacttaa aaattttggt ccttttatca atgagaccgt agatttttca
    12241 cgtttgacag aagcaccgct ttttttgatc agcgggaaga caggagctgg caaaacgacg
    12301 atttttgatg ggatcacctt cgcacttttt ggtgaaactt ccggaagact tcgctctgga
    12361 aaagagatgc gttctttgtt tgctacacca gacgaagaaa caagcgtgac tttttctttt
    12421 gaacatcagc agatgagcta tgaaatcgaa cgaaaaccag aacaagtttt agcaaaacga
    12481 aaaggaaacg gaacaaaaaa acaggcagcc aaagtaacgt tgaccatttt tgatgggaaa
    12541 ggaaaagaaa taaaacaaat cacaaaacgt acagaagcag atcagttgat cagagaactg
    12601 atgaatctcg atgcgaaaca gttttctcaa atcgttttac taccccaagg agaattccgt
    12661 aattttttgg tttcatcaag cagtgataaa gagactgttt tacgtcattt attcggtact
    12721 caatttttcc aacagttcaa tgagcgatta aaagaaaaag caaaacaaca gcaacaaaaa
    12781 ttggatcatt tagagcaaga gctgcatctt ctgcaaaaaa ggtttgtttt agtcaaagaa
    12841 gaggaaccag cagcagggtt tgaagccgtt ttagcccaat ggacaaacca tcaggcaata
    12901 ctcgaaaaac aaatcacgga agaaaaagaa gctctaacgg aacttcagga aaaacaaaag
    12961 caactagaaa attcctacta tcgttttgaa agcttgaaaa aaagttatga agaaaaaacg
    13021 atattaataa acaagcaaaa ggaattagct gctcaaaaag acgaaataga ggaaaagaaa
    13081 cgatggattg ggtattatga atttacgcaa cgattagtcg aaccaatcca gcgcctacaa
    13141 gaaataaaag ttgaaaaaat agaactgtca caaaaaagta gtgagcaaac aaagaaacta
    13201 gcgatgacta cgcagaatta tgaagagtgg caaaaaaatg aagcaaaccg cgtacgccga
    13261 caaacaaaaa tcaaagaagc tgctcaaaaa ctgcaaaaca aacagatgat ggtgccaatt
    13321 gtcgaatcct tacgtagtaa aaaacaagac gcagaacaat taacaatttc attggataaa
    13381 gaagaattga atgccgagaa gctgtatcaa aatctcgcta tctatcagga aagaactcga
    13441 attcttcaag aaaatttact ggatcaggaa aaactgcaag aagatcgtct tgcttttgga
    13501 cagttaaaat atctagatga aaagcagcaa gaaatagaaa aacaaaaagc aaaagacact
    13561 gggtcgctcg cacagataag agaagaactc aaaaaagcaa ctgaagaaat aacaaaaaat
    13621 agtcagctat tgaaagaaca gacagaacaa gcagaacagc tgaaaagcca atgggcaaag
    13681 cagcaaattg ctcgtcttca gctttttttg cgtccagggg agccatgtct tgtttgtgga
    13741 tcaacggaac accccataca acaattaaaa cacgaacagc caaataagga agatatctta
    13801 aaagtagaac aacaactggc agaagctgag tctgctgtag aaagaactca gcaaatcatt
    13861 gccaaaagtg aagcacatga aaataatctt caacaacaat tatcagattt agaacaaaaa
    13921 atcatggcaa cgaatataca attggctgaa caagaagaac acttgcaaca ggctttgaaa
    13981 aaggcatttc ctgagataac agaacaaaaa acaaaaacaa ctcttgtagt aatcgaacaa
    14041 tctttagata gacgaaaaag caagatggcc aatgcaagaa tagagctgga agaaataaga
    14101 caacaagcag aaaagctcga acaacaatta gctgtctaca aacagcagca gacagaaaaa
    14161 aataatcagc tccagcaact gcaaggagaa atcaaaagtt tagaacaaca attgcaagat
    14221 acggatagta actgtttaga agaggagata cgacgacttg aaaaacagtt agaagaagac
    14281 tcgaatcaac tagctgttga gcagaaagca ggagtgcaat tgttgcaaga tcttcatacg
    14341 cttcggacac agcttgatct tcaacatgaa caaatagaaa aaatagatga aaaaatagaa
    14401 aaggaacaag aaagaatagc taaaaagtta gaaagccagt cgtatttttc aacaattgaa
    14461 gaaatctgtg catttgcaca acagcaagca caatataaag aaaaccaacg tacagttact
    14521 tcttatcatg aagagcaatt agtgacagct gaccggctgc gtcaattaga aaatatccag
    14581 ctaactgaga cattcccaga tacagaagag atcagccaac agttagaaga aataagacgt
    14641 atgatcgaaa taaagcaaga aaagatatac ggtttacaag aacaaaaaat tagtaatcaa
    14701 aaaatctacg atgaatgtct ttcgatttat cacacaagcc agacgaaatt agatgagctt
    14761 acgcaattac agcagctttc gcaaacattc aacggagaaa atcctaagaa gactagtttg
    14821 gaacggtatg tgcttcaggt ttatcttcaa gaagtgttac aagtagcaaa tgatcatctc
    14881 caacgtttaa cgaaaaatcg ttatcaattt gagctagcgg ataccattgg cagttatcga
    14941 gggaaaaccg gattagaaat caatatctat gatgatcagg caggtatgtc tcgaagtgcg
    15001 cataccctgt ctggcggtga gagttttatt gcagcacttt ctttagcatt agctcttgcc
    15061 gatgtgatcc agacacaagc tggtggtgta gcaatcgatg cattgtttat tgatgaagga
    15121 tttgggtcat tagatgaaga agctttggaa atggcaatgg aagctttaga aacgatcgaa
    15181 agtgaaggaa gaatgatcgg catcattagt catgtaagag aattgaaaga acgagtatta
    15241 caacaaataa gaattgatac agaaggtagc ggacaaagca aaatacgcta tcaacttgga
    15301 taaaaaggga gattggtaac tatgaaatgg agtattccag aaaaagtcat tgcacgtgga
    15361 cgtcaatact tgcaagaagg ccgagtgtta tcggttgtcc ctgaccaaga agaaaacgtg
    15421 tggcatgcag aagtcttggg cagtgaattg tatatggttg atttggatgg tacagcaaaa
    15481 gagatagatt actgccaatg tccctattgg gaggaacata aatattgtaa gcatacagtt
    15541 gctgtggaac tttatttacg gtcgaaaaat ctatctcgta tcatgaaaaa agaccagcca
    15601 atgctagaac cggtaaaagc aacaagtgag ggagaaatca ttgcaaaagg tttttctcgt
    15661 ctaaaaacac aaaacaatcc tcaagcggtg caacctttga ttattgaata ccaagtagaa
    15721 acgattgaga ctaatcagta tcacccagag ctttctattt tggcacttta cttgcgtatc
    15781 ggttcattgg catcaccgaa aaaaacatat atcgtaaaaa acatctatga ttttttacaa
    15841 gcttacacag aaaaagaaac ttacactgtt aataaacagt accagtttcg tctagataaa
    15901 cgggcgtttc aaaaagaaga tcaaaaaata ctcacgcatc ttgcaggaag tgctcagacg
    15961 catcaattat taggtacgaa cggcttacaa gtcaaaggaa aactagataa aagatatctg
    16021 cttctcccag tagaacaagc ccgcttcctg ttagagcaga tgaatcagac tacacgtttg
    16081 catctgcaga taaatgaaca aaacgatcaa ggaatacaat tttccgatca aaacaaacct
    16141 ttatcattca aagtggaaaa atttggagaa gattatttgc tgcaagcatt gaatgatttt
    16201 gattttttct ttatgcatta tcagtgggga gttatccaag ggacatttta ttctctgacg
    16261 aaatatcaac aaacggttta tcaaacttgg aaacaattga ttcgccgatt ggagaaacca
    16321 gaagtagtgt tcaagaaaaa agaattaccg tctttgttta aagagattat ccctctgctg
    16381 tcagagatcg gcgacgtagc tattgcccct gcagtagaag aggaagtagc agatatcccc
    16441 gtcgaattta ttttcttttt ccgaaaagca aaaggaaaaa tccaagctcg agtcgatttc
    16501 gtctatggcg aagtcatcta ttcgactgac ccgaagcatg aggtctcgac agaacaggct
    16561 tttcaggtgt tacgtgacac agtagaagag aaacgagtac ttgatctatt cagaatgtat
    16621 cgctaccaga aaaatgaaac tggttatgaa cgtccattgc caagcgggga agaactatat
    16681 gcctttttcc gcacagaact atctgtcttc cgtcagtttg gtgaagtcag acttggaaga
    16741 aaattgcgag agttgtattt agatgcgcat aaacatcaac cgaaaatcga agtaaccgag
    16801 accggttcat ggctcgatat tcgattcgat gtgacaggga tagaggagca agaaatcgat
    16861 catgtcctgc aaagcttgct gagaaatgat gctttttata cattagaaaa tggtcaggtt
    16921 ctttcttttg attcagaaga atttcaacaa acaagccaag tgttgcaaca attacgggaa
    16981 tcgatacgta cagaagaagg aacgatccat gtacctaaaa atcaaggatt gatcattcaa
    17041 aatcaattgg aaaaaagcaa tgctactttt agtgaatcgt tccaaacgat ggtacaagat
    17101 ctcattcatc cagaaagata ccaggcacag cttcccaaag gattgaatgc aacgatgaga
    17161 gattatcaaa agcaaggttt tcgatggttg aagatgttag gtcattatca gtttggcggt
    17221 attttagccg atgaaatggg acttgggaaa acactacaga caattgcctt tttactttcg
    17281 gaaaaagaag aacggaaaag cttctctgct ttgatcgtag cgcctgcgag cttaatttac
    17341 aactggcagg cagaggtgag aaaattcgcc ccttctttaa gtatccaagt aatcaatggg
    17401 aataaaaaag aacgtgaaga attactggct aaagacacag atatccgagt gacttcttat
    17461 gccagcttaa gacaggatct agctaattat cagtcgcaaa aaattgatta tttgattctt
    17521 gatgaggcac aaatggtcaa aaatagcagt acgaaaactg cacaagcatt gagagaatta
    17581 gctgtacctc agcggtttgc actgagtggg acaccaatcg agaataattt agaagaattg
    17641 tggtcattgt ttgcaacgat tatgccagga tttttcccga ctaaaacaaa attcagggaa
    17701 cttgccgcag aagaaattgc gcaaatgatt cgaccgttta ttttacggcg agataaacaa
    17761 actgtgttga aagacttgcc ggaaaaaaca gagatgaatc tatattctgc acttacagaa
    17821 gaacaaaaaa ctgtttattt agcttacttg cgtcaaatgc gtgaagaaat cacatcaatg
    17881 gattctgaag cattcaagaa aaaccggatc gggatacttg ctggtctgac aagactgcga
    17941 caaatttgct gcgatcctcg tctgtttatt gaagattacc aaggcggttc cggcaagctc
    18001 gaacaagtaa aagatctact ggtagctgcc aaagagaaca aacgaagagt tttgctgttt
    18061 tctcaattta cagggatgct gactatcttg caagaagagt tagccgagct agggatctcg
    18121 acattttatt taagaggcag tacgaaacca caagatcggt taagtatggt agacgcattt
    18181 aatgctggcg aaaaagatgt ttttctgatt tccttaaagg ctgggggaac tggattgaat
    18241 ctcacgggag cagatacggt catcttgtat gacctttggt ggaatcctgc cattgaagaa
    18301 caagctgctg gacgtgcaca tcggatcgga caaaaaaatg tggtagaagt gtggcgtatg
    18361 atctctgaag gaacgattga ggaacgcatg gattcactcc agcaagaaaa acgcgaactg
    18421 ttccaaaaag tgatccaagg taatgaagaa cagttgacga aactgactga agaagacatc
    18481 cgcatgattt taagtgtagg agaaatcgag gagtaagaga ctcgaaaaag cgttcagtaa
    18541 tgggtaagaa agcctttcta aagaagcgat tgtttatttg atttaaaaaa tagcaaggag
    18601 gctgggattc cattttatcc cagcttcctt gctatcattt ttttatttct atttttaaag
    18661 gttatacaaa gattgtcttc attgtctcta acagctgatc aaaagaagaa atctcgatat
    18721 cgcaaattgg agtctgttca attttgcgtt ctcgatggtt gaaccaaagc gcttgccagt
    18781 tagcactttt tgcacctaga acatcattgt cgtaattatc gccaacgtat aaggtctctt
    18841 ctggaagcat atgaaattct ttctcagcta gctgaaaaat ctctttttct ggtttttgga
    18901 aacctgttgc ttgagaaatg agcatattgc gggaaggaat ccaattgttc aattgaagtt
    18961 gcttcagttt ttttgtctga tggtcagtcg gcccatttgt gataattcct aatgggacat
    19021 tcttttcctt caagaaatcg agggtttttt tgacctcctc atgcaagcag atattatcaa
    19081 gttcttcctc gtaaattttt tgaaataaga ggccatcttc ttccgtaata tgagggtagt
    19141 ctaaatcttt tagtgattgg ctgatccgat gtgctcgcat atattctagt gtccaatctc
    19201 ctgccattac ttttgggaag ttttcatcac tatgatggcg gaaccggata tatagtggat
    19261 gcatatctgc atctgaaaca agcggaacga ctcttttgac cgcgtttcga aatggctgct
    19321 gctgatcata catcgtatca tcaacatcaa acacaactga tttaatcaaa attttacacg
    19381 cctttcggtt ttcattgatt ttttcacaaa tccttgacta ttgtaacaga aaaaattgtc
    19441 taaaaaagct gataaataaa ggtttttctt actatatttc tatttccttg acagaataag
    19501 gtttttatat ttcagttttt ttcactaaaa atcgtgaaac acgtcaataa gtttgatgaa
    19561 caaattaatc attatggtag aagtcgattg atttatttta atgcaatctc tgtggaattt
    19621 tcgaaagatt tattttttt
//
LOCUS       DADVXB010000046        19454 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.047, whole genome shotgun sequence.
ACCESSION   DADVXB010000046 DADVXB010000000
VERSION     DADVXB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.047"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1526)
                     /locus_tag="KB902_001241"
     CDS             complement(<1..1526)
                     /locus_tag="KB902_001241"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBB6808081.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(1541..2188)
                     /locus_tag="KB902_001242"
     CDS             complement(1541..2188)
                     /locus_tag="KB902_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBB6808082.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(2372..2701)
                     /locus_tag="KB902_001243"
     CDS             complement(2372..2701)
                     /locus_tag="KB902_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBB6808083.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            2878..3606
                     /gene="sfsA"
                     /locus_tag="KB902_001244"
     CDS             2878..3606
                     /gene="sfsA"
                     /locus_tag="KB902_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBB6808084.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            3622..4635
                     /locus_tag="KB902_001245"
     CDS             3622..4635
                     /locus_tag="KB902_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6808085.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            4635..5912
                     /locus_tag="KB902_001246"
     CDS             4635..5912
                     /locus_tag="KB902_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6808086.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            5975..8677
                     /locus_tag="KB902_001247"
     CDS             5975..8677
                     /locus_tag="KB902_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6808087.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKKIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            8829..9146
                     /locus_tag="KB902_001248"
     CDS             8829..9146
                     /locus_tag="KB902_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808088.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            9176..9496
                     /locus_tag="KB902_001249"
     CDS             9176..9496
                     /locus_tag="KB902_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6808089.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            9604..11064
                     /locus_tag="KB902_001250"
     CDS             9604..11064
                     /locus_tag="KB902_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6808090.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            11132..11353
                     /locus_tag="KB902_001251"
     CDS             11132..11353
                     /locus_tag="KB902_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808091.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            11384..11566
                     /locus_tag="KB902_001252"
     CDS             11384..11566
                     /locus_tag="KB902_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBB6808092.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            11566..11979
                     /locus_tag="KB902_001253"
     CDS             11566..11979
                     /locus_tag="KB902_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBB6808093.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            12102..13283
                     /locus_tag="KB902_001254"
     CDS             12102..13283
                     /locus_tag="KB902_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808094.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(13354..13518)
                     /locus_tag="KB902_001255"
     CDS             complement(13354..13518)
                     /locus_tag="KB902_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808095.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            13672..13745
                     /locus_tag="KB902_001256"
     tRNA            13672..13745
                     /locus_tag="KB902_001256"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13706..13708,aa:Arg,seq:cct)
     gene            complement(13814..14953)
                     /locus_tag="KB902_001257"
     CDS             complement(13814..14953)
                     /locus_tag="KB902_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6808096.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFEKFEVK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINAVFDSLYKNDN"
     gene            complement(15063..15698)
                     /locus_tag="KB902_001258"
     CDS             complement(15063..15698)
                     /locus_tag="KB902_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBB6808097.1"
                     /translation="MDGIFGFTGIVLFFIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     AVGFSLSSSNEANDNNKQESSSSETQTTTSNSSNKSLTQFEEFLEANNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWSDISTTPKV
                     SYVIFAKDVNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(15732..16193)
                     /locus_tag="KB902_001259"
     CDS             complement(15732..16193)
                     /locus_tag="KB902_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBB6808098.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTIMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQDEFDFKKKELLGL"
     gene            complement(16277..16705)
                     /locus_tag="KB902_001260"
     CDS             complement(16277..16705)
                     /locus_tag="KB902_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6808099.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(16710..17084)
                     /locus_tag="KB902_001261"
     CDS             complement(16710..17084)
                     /locus_tag="KB902_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808100.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            17387..17572
                     /locus_tag="KB902_001262"
     CDS             17387..17572
                     /locus_tag="KB902_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808101.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQEHIETVKKILGIQ"
     gene            17585..17923
                     /locus_tag="KB902_001263"
     CDS             17585..17923
                     /locus_tag="KB902_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBB6808102.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            17910..18080
                     /locus_tag="KB902_001264"
     CDS             17910..18080
                     /locus_tag="KB902_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808103.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            18084..18257
                     /locus_tag="KB902_001265"
     CDS             18084..18257
                     /locus_tag="KB902_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808104.1"
                     /translation="MKKSLMTINEKQLKENFNDLIKEFVKETGEFPNQIHLVAEGHSQ
                     YQAVKFEMKKQIY"
     gene            18294..19019
                     /locus_tag="KB902_001266"
     CDS             18294..19019
                     /locus_tag="KB902_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6808105.1"
                     /translation="MQELVILKNKEAVTTSLQVAEAFEKKHKHVLEAIESVKRSVENS
                     ANVEDVLNFEQMFVEGNEPDTYGRSRRVFFMNRDGFSLLAMGFTGSKAISFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
     gene            19198..>19454
                     /locus_tag="KB902_001267"
     CDS             19198..>19454
                     /locus_tag="KB902_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808106.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNVKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVIEDGLTDALEE"
BASE COUNT         6277 a         3312 c         3797 g         6068 t
ORIGIN      
        1 caatcgttta attttccacg ttcacgatac cagttatctg gttgccagat ccattcgaat
       61 ccgtcttttt caagtagttc gaaagctgct ttaggtccca ttgatccagc tttgtagttg
      121 ggaaaatccg gttgtgtttg gtcccaagct tttcgaatga catccacgat atgccaagat
      181 tgagcgactt cttcccaatg agagaagttc gttccatcac cattcaacgc atctaatagt
      241 aatttttcgt aagcttctgg gctattttca accatttctg cactatttct aaattccaat
      301 ttgattggtt ccgtttcaaa tccttgccct acttctttcc cattcaagga taaagaaaat
      361 ccttcagttg gctgaatata gatcgttaga acattaggtg gaagtgtcgt atcgtcacat
      421 ggttcatcga cagatgtttt gaatacatta acaggaactt gtttgaatac gatgttgatc
      481 cgagtccctt tttcagtcaa acgtttgcct gtacgtacat agaaaggaac acctgaccaa
      541 cggaagttat cgatagtgaa tttgcctgcg acgaatgttt cagtctctga ttgagcatcc
      601 actttgtctt cttcgcgata gcccttgaat tgtacaccat ccaattcacc ttgagcatat
      661 tgcccgcgaa cgaagttttc taacacttct tcttcgttat aaatgcggat agctttcaat
      721 gctttgatct tttctgtacg gatttctttt tcggaaaatg ctactggcgg ttccattgca
      781 agtaatgcta caacctgtaa aatatgattt tgcaccatgt ctttaagtgc gccactatga
      841 tcgtagtagc ccccgcgatc ttctacaccg aggttttcgc caaaagtaat ttggatattg
      901 tcgatatagc gattgttcca ttgagcctca aaaatattat tggcaaaacg gatagctgag
      961 atgttttgga tcatttcttt tcctaaataa tgatcaatcc tgaaaatatc ttgttctggg
     1021 aatacttctc tgatttgctg gttcaattca aaagcagact ggtaatcaga accgaacggt
     1081 ttttctatga tcaaacgatt gaagccattt tttgtcataa tattttgtga tttcaaatga
     1141 gaaacgatcg ttccaaaaaa ttgaggtgcc atagccaaat aatagacacg gttaccgttt
     1201 aattgatagt gtccatctaa tcggtcagac aattctttta atgtctgata atgcgttgaa
     1261 tcatttacat catgggattg atagtaaaaa tggcttgcaa aggtagttgc ttcttcatct
     1321 gaaggattca atgcacggat tgtttctttg acaacttcac ggtagtgctc atcgctccag
     1381 ggacggcgag cggttccgat tacagcaaaa tgctcgccta aatttccttt tctgtaaagg
     1441 cggaacaaag acgggtacaa tttacgctgg gctaggtcac ctgtaccgcc gaatatcgta
     1501 aacaatacat ttttttcatt agacatgtgg atacactcct ttatatttta tcgacaaaaa
     1561 tcgtgctggc cgccttaaag ctgacgggga ttttctttct atcattttgg atagtgatcg
     1621 gtccttcata agctgcgatg tcaacgatct catattcttc gttgatattc aggtcaatag
     1681 tgactaagta atccaacaat tctttttcat caagcactcg tgcgatacgc acttttgtac
     1741 cgacaggata ggactccaat gtttgtcggc gttcttcatg gacaacttcc tcttttttag
     1801 gaatcgatcc tccatgagga caatgttcag gatgattcaa atagttttct aaatgatctg
     1861 caagatgttc cgaagtcaca tgttccaata cttcagcatc atcatggact tcattccagc
     1921 tatagtctaa atgttcaact aaaaaaactt cccataagcg atgtttgcga atcagactgc
     1981 tagctttttg cagtccgctt gcagtcaatt gtacaccttg ataaggggaa tgttctacaa
     2041 gctcttcttt cacaagttta gaaatcattt cactgacaga tgcagctgag acatctagac
     2101 tagatacgat ttgtttattg ttgactttcg ttgtatctcc acctagttct aaaatgattt
     2161 tcaaataatc ttctcgattt ggtgtcatat tcgatcatcc tttcatggta aaaaaccatc
     2221 attagtaagt gtaacaaaaa aaacgttaat tgactatttt tctaaataaa aaacaaagga
     2281 tttttagacg tttttacaac aaaaaacgaa agatgataga gaagactcat tctttcgttt
     2341 ataaaggata tatatataca ttgggaggga tctatttttc agataacaac ttatatgaag
     2401 tgtctgcaga ttcgtcataa agagtttgtt cgggataaga aaagataaga taaaaaccat
     2461 actgatcacg tacgactaaa cgatattcat ctatttctac cacagatgtg ccaagagact
     2521 gaccgttgat caaaaacgtg taatcagatg taatctgtaa ttgttgtttt tgctggctat
     2581 cactaaagaa ccatgtacct tgatactttg agagtccttc tgacttttcc gcttgttttt
     2641 tctttttcaa gtaaataaaa cttgagagaa cggtaatgag tgaaccaaga aaatagatca
     2701 ttttttttat caccaaatca ctcctttatg agaaaataat cgcatagaca tattctttct
     2761 tctttatttc attgtaccga ataaaagcta aaatttctct aagactttcg actggttttt
     2821 ttactgtttt tctacaaatt atgataggat acatagtagg aagaaaggtg acataatttg
     2881 aagtatcagc aagtggaaat agcttttttt attgaccgcc cgaatcggtt tatagcacat
     2941 tgtatgaaaa aagacggaga aataattatt gcgcatgtca aaaatacagg tagaggaaaa
     3001 gaggtcctga taccaggcgc tgaagtggct attgtatttg ctcctggacc taaacggaaa
     3061 accgcctatg atctgattgc tgtaaaaaag aagggtgact ggtttaatat cgatagtcaa
     3121 ttgcctaatc ggctggcaat tgatggtatt ttagacggca cgatcctttt accaggatta
     3181 actggtccat ttacggtata caagcgtgaa gtaacttatc ttcactccaa atttgatatt
     3241 tatttagaga cggtggtcgg acaaaaagca tttgttgaag tcaaaggtat gacacttgaa
     3301 aataaagcga ttggtgcttt tcctgatgcg cccacactca gaggattgaa acatatagga
     3361 gaattaacgt atgccgcaca agatggttat gccgcttatg tcttgtttat tgctcagttc
     3421 gaacatcttc atctggcaac gatccatgaa gaaatgcaac cagcactagc tgatatggtt
     3481 cgacatgcgc agcaaagcgg agttcaaatc ctcgcctata attgtcaagt atcggcagat
     3541 gaggtaactg tcaagcaggc cattccattt gatgtagata tcccttttga agatcctata
     3601 caatagaaag aaggtaaaat aatgatcaac ttaggtatta tcggaacaaa ttggattact
     3661 catcaatttg tccaagcagc tttaagcaca aaaaaatatg aattgacagc ggtatattct
     3721 agacatttgg aaaaagcaca ggaatttggt tctcattatg aaggggatat cgaattcgca
     3781 acagatttga agactttttt caatattact catatggaca ccatttatat tgcttctccg
     3841 aatagtcttc actttagtca agctaagcaa gcaattttgg caggaaaaaa tgtgatagtt
     3901 gaaaagccag ctttttcgac gccaaaagaa atggatgaaa tcatccattt ggcaaatgaa
     3961 cacaatgtgt atttttttga agcagcaaga aatatccatg aatcaggttt taaaaagatt
     4021 gccgattact taccattaaa agacgagata atcggtgcaa atttcagcta tatgaaatat
     4081 tcttcgcgct atgaccaagt attagatgga gaagaaccga atatcttctc gactcatttc
     4141 tcaggtggtg cattgatgga tttaggtgtt taccttgtat atgcagctgt tgcttggttt
     4201 ggaatgccaa aagaagtcca ttatttccca agaaagattt ctactggtgt agatggtctt
     4261 ggatggggga tcttacgtta tgagaatttt gatgtatcga tccagccagg taaaatcggt
     4321 gattcttatt taccgtcaga gatttatttt gactcaggaa cgctagtgat gaatggagtc
     4381 aatgcaattg aacaagcaca atttcatgat cgcgcgcata aagaaatcat tgatttggcg
     4441 gtaacagctg cagaaaatcc aatggcagat gaagcagagg attttgccaa tgtcatggct
     4501 catccgaaag atccagcttg gggattgttg tatgaagagt ggatcgagct agctagaaat
     4561 gtgaaccaag tgatttatga tttaagaaaa aatggcggca tcaaattcga tgcagataat
     4621 gaggaagatt tttaatgaac gaatttgtac aagtatttcc cgaaaattgg cagaaaaaat
     4681 atgaggataa agggtttatc tcaccttctc ttattcaacg agcagttttt cagccactaa
     4741 gtaataaaca aagtatagta gcggtttctc ctacaggttc aggtaaaaca ctggcttatc
     4801 tttggcctct actactaaac gtggaaccag gtgaagcaag tgcgttggtc atttttgctt
     4861 cttctcaaga actagctatt caagtagcag atgttgcacg tgaatgggga aaagacaaag
     4921 agttgaaagt ccaatctttg gtgggcggag ccaacgtcaa acgtcagatt gagggtttga
     4981 aggaaaaacc agaaatcttg attggtacac caggaagaat attggaattg atgaaagcaa
     5041 aaaaaataaa agcacatcaa gtgaaaacaa tggtatttga tgaagcagac cagctatttg
     5101 acgctgggaa cagccaaatc attgatcaaa ttcttcatca agctccaaca gagtatcagc
     5161 tagctttttt ttcagcgaca gcagatcgtt cccttgaaag cattgaaaaa atcactggga
     5221 aaacgtttga gacaattgac gtgacagcag aggacgattc tcgaaaagga ctgagacatt
     5281 actttttacg tgtaccgata cgaaagaaag atgactactt gagacgtctc acgcatatag
     5341 aagattttca tggtctgatt ttctttaatc aactgactga attaggcgta atggaagaaa
     5401 aattgctgta tagaggtgta ccggtaggaa gtctggcctc tgatcagaac aagctactcc
     5461 gaaaagcagc gctagaacaa ttcaaaaaga aaatggtcag agcacttttg accacagatg
     5521 tggcggctag aggtttagat attacaggtc ttccttatgt agtgaatgca gaagttccgt
     5581 taagtgaaga agcttatttg catcgttcgg gaagaactgg tcgaatgggt aatgaaggaa
     5641 tagtaattac actcgtacaa gataataatc taagagattt aaaacggctt ttacgtccat
     5701 caaatataac acttgaagag atttttttat acggaggtaa gctgcaaact gagcagccaa
     5761 ccaaagaaga tgcagctcct gcagtaaata aaaagtatgc gaaaactttt tctggaaagg
     5821 agcagaaccc agaatataac aaagaaaaaa taagaaaaaa agttaaaaat aaatcaaaaa
     5881 aagagagaaa taaaggagca aggcgcaaat aagcgccttt ttatgctatg attatgaaaa
     5941 cgggaacaaa attggttgcc agaggagggg ttatgtgaaa gaacgtcaag aagagatctt
     6001 gcagctattg acagaaaacc aacaaggatt gacagcaagt gatgtagctg agcgcttaac
     6061 tatcgatcga agcaatgcaa gccgatattt aagtgaacta tacaaggccc atcatattgt
     6121 aaaaaccgct ggccgaccag tcgtttactc tttgccaacg gaaaagtcaa aatctgatga
     6181 agtgcatgtc gactcttcta cgcaagtgac ttttgaaaca ctcgttggag aaaatgattc
     6241 tttaaaagtc agcatacagc aggcaaaagc tgcgattctt tatccaccgc gggggttgca
     6301 tacgattatt tttggagaaa ctggtacagg gaagtcgatg tttgctgaat gtatgtatca
     6361 ttttgcaatc gattcagaga tgctttctgc agatgcgcca tttgtttctt tcaattgtgc
     6421 ggattatgct caaaatccgc aactgctctt tggacacatc tttgggatca aaaaaggggc
     6481 ttacacagga gcagctcaag atagtcccgg tctaatagcc aaagcagacg gcggtatatt
     6541 gtttttagat gagatccacc gtttaccgcc ggaagggcag gaaatgctgt ttactttcat
     6601 tgataaaggt atttaccgtc cgcttggaga aagtgcacaa gtacatgaag catctgttca
     6661 gatcattggg gcgacgactg aatcttcaga aagtttctta tctacgttca atcgacggat
     6721 tcctatggca atcaccttgc cgaatcttgc ttcacgttca ctggatgagc gttatgaaat
     6781 catctctctt tttatcaaac aagaagcgaa tcgtttgaat caacgtatcg atatcgaaaa
     6841 agaagcgatt cttgccttca tgctttatga tgcggaagga aatatcggtc aagtgaaacg
     6901 agacttgaaa ctagtctgtg caaaatcttt tttacattac cgtactcatc atgagaaaaa
     6961 gctaatcatt cgaaaagaag aactttccct tcaagtacaa aaaggattac tgaaaatcaa
     7021 gaaaataccg gaacgtctcg accgattcat ggacagcaaa agtcagtatt tgacatttga
     7081 accaggattt gctgatgttg tctggtcaca agatccagaa cgaaacatgc aggtctataa
     7141 cgatattgag gaaaaagtca cttctctttc cgaaaccggt gtggagaaca ttgatctaga
     7201 gaccctcatt tcaaaagatg tggatgctta tttccagaca tatgtcaaag aattgactaa
     7261 aagttcgatt cccaaagatc ttttgccaga tgaaatctgg cggttaacca atcaattgta
     7321 tgatgtggct gaaaaacggt tagaccgtat ttataatgaa aaagctcgtt ttgcttttgc
     7381 tttgcatctg caaagtacat tggatcgtgt gagagaaggt catatgatcg tccacccaga
     7441 tttgaataac gtacggaaaa attttaagag ggaattccag gtagcaatcg atctttcaac
     7501 gatcattgaa gaagaagaac aagttgagat tccttttgat gaaatcggct ttattagtat
     7561 gtttctttct atcaatctag gagaaagtga gcctgttaaa gaaaacaaag tagatgttct
     7621 catattgatg cacggcagac agactgcttc aagcatgttg gagatggcac aagaactatt
     7681 aggaacaaaa gtagggaaag cttttaatat gccactggtt atggaagttc aaacaatgta
     7741 tgaagaagtg ttacaatatg tcaaaaacta tcaagagcat ttgacgaatg gcctactctt
     7801 gttaacagat atgggatcat taaacacctt cagtgatttg atttatgaag agactggcat
     7861 tcggacgaaa gctatcacga tgacaagtac catgattgtg atagaagcga tacggatggc
     7921 aagtgttgga agaagcttag aagatattta tcaaaatatc cagctttcct ttgaatcgat
     7981 cgtacgtgat cagttcaaag cggaaaagtc tgaaacttta cagcgtaaaa aagccgtaat
     8041 cgtgacatgc tttactggtg aaggagtagc tgccaaatta tatcagcgta ttatgccagt
     8101 gattaatcaa aataaggtag aactgatcca gatgcagttt ttagaacgtg aatcattcaa
     8161 aaaacacatc gatgccttat tggaagaata tgagatcaaa gcaattgcgg gaacagttga
     8221 tgttgattat caaaatatcc catttttttc agcctatgac gtttttgatg atgaaaaact
     8281 aaatatttta aagcgtatag ctgatgatga gatcccgaca gctaaaattg tcgattcact
     8341 tgctggatca ttaagcgatg tcttttctat tgatgaactg atccgttcat tgcaaaagac
     8401 agttcagcag atccagaccg atttgtcgat tatcgtggaa cctggagtag atactggaat
     8461 cgttatccat ttagccttca tgttagacgg attgatcaaa caagaaagcc atcggcaatt
     8521 tgagaaactg tctattttct caaaaattta tcgtttggaa atggatatcg ttcgggcaaa
     8581 cttgatggca ctagaacgaa aatatcaggt aaaaattcca gaagatgata tcgcatttct
     8641 tacacaaatg tttcttgaaa ataaaataaa aaaatgaaca cactaatcat actgtttaca
     8701 cactaaacat ctgtgtgcgc actataaaaa agagctaaaa agcatgaaaa cgctatttca
     8761 gctctttttt ttattggcat gcttcttgcg ttatataaaa gtgtaaaaaa ataaaaggag
     8821 tgttaaaaat ggcaaaaaaa acaatcatgt tagtttgttc agcagggatg agtacgagtt
     8881 tattggtcac aaaaatgcaa aaagcagcag aagaaaaagg gatggaagcc gatatttttg
     8941 cggtctctgc ctcagatgca gataataatt tagaatctaa gaatgtcgat gtattattat
     9001 taggtcctca agtacgtttc atgaaagctc aatttgaaca aaaacttgcg cctaaaggta
     9061 ttccattaga tgtcatcaat atgcaagact atggcatgat gaacggagaa aaagttcttg
     9121 cacaagcaga aaatctaatg aaataaatca agtatgcagt tgggggtata acaacgtgga
     9181 agatcaacaa aatctagaag ccatcatggg gttaatcatg tttggcggta atgcaaagag
     9241 cgatgcaatg gaagcgattg cggctgctaa aatcggtgat tttgagttag cggataggaa
     9301 aatcgctgat gcagaagaat cacttataca agcgcatcat gcacaaacag acatgttgac
     9361 acaagaagca caaggaaatc atatgcaagt gacattattg actgttcaca gtcaagatca
     9421 cttaatgaca tctattgcgt ttactgattt agcaaaagaa atcatcgaac tttatcgtcg
     9481 cgtatacagc gaataaatac aacttctttt ttgaacggaa gaagaaaaat ttttgaacgg
     9541 attttttatt ttgttataag gagaactctc tttatataaa aaacttatag gaggaagtaa
     9601 aaaatgaacg gactatcaag ttggatggag aaatacatcc tgccggttgc cgcaaaaatc
     9661 ggagcgcaaa aacatttagt tgctttgcgt gatgctttta tcggcacact gcccgcaaca
     9721 atggcgggat cagtcgctgt aatgatcaat gcaattattc gtgatttacc gcaacagttt
     9781 aacagtacct atgctgacag tttagcagca gacaaaggaa tctttgccgt attgaatgtc
     9841 atcatcggaa tcaatggttt tgtctggaac ggtacactag caatcgccgg attgatcttt
     9901 gccttttctt gggggtataa tcttgcccga gcttatggag taaatgatct agctgggggg
     9961 atcgttggtt tagctacctt gattcaaggt atttcctttg gtccagcatt atcagcagca
    10021 ttagatgtga atgttccttc aaatgtcgca gatgcaatca atagttctga gattggtgca
    10081 acgattgcag atggcacact gtcagttgga ttatggggtt ggctaaaact agatcatttg
    10141 aatggaaacg cttattttac agttatgatc atgggagcta tttcagtcat tattttttgt
    10201 aaattgatgc ttgccaacat tacgatcaaa atgcctgatt cagtaccacc agcagtatct
    10261 aaagcatttg cagccatttt accagcgacg atcgctttat acgtcattgc tattatcaat
    10321 tatatcgtag gtcgtgtagc tgatgggcaa ctgatcattg atttggtgca aaaatatatt
    10381 gcagaaccat tcctaggatt atctcaaggg ttgggagcag tattgatcgt cacagtattt
    10441 gttcaagtat tctggttctt tggtattcat ggaccaaatg tattggcacc agtgctagag
    10501 ggaatctggg gacaagcaca actaatcaat attgatattt tccaaaaagg ttataacgga
    10561 aaaactggta caccagccgt gttagatgca atcgaagatg gaaaagctta tatgtgggtc
    10621 cgcggatcgt tcgatgcttt tgcatggttt ggcggatcag gcggaacgat cgtcttactg
    10681 atagctatct tgattttctc taaacgtgca gattatctaa cagtagctaa attatccatt
    10741 gggcctggta tcttcaatat caacgaacca gtgatgtttg gtctgccaat cgtattgaat
    10801 gcaatcatgt ttatcccatt cttgattgct ccagtagtag caacagcaat tggatggaca
    10861 gctacttatc ttggcctagt cgctccggta tcgcagcaag tcacatgggt agtaccgccg
    10921 ttcttattgt cattcttagc aacaggagcg gattggcggg caccgatcgt aacattagta
    10981 tgtatggtcg tgactttctt gatttgggca ccatttgtca tctctgcaaa caaaatggac
    11041 cctgccgcag gcgaacaaca ataagatgaa cgtgaggagc gggacgcttt aagtttcgtt
    11101 cctcataatg aattttcgag gaggaactga aatgattaca attgccagtg caatgcaaca
    11161 agatgaaatc aaagaattgt tagaaggata caatgaagaa ggaatgactt ttacatttaa
    11221 agaaaaacaa ggaatcaagc tgttctttga aacaagtgca gaagatccgg aagttgcggc
    11281 taaaaaagca aaggaactaa tcaaagcaca gccttgggga acagtccttt attttcaatc
    11341 aacagctgtt tagaaaatgg tttaaaaaga taggatggtt gagatgataa aaaacggttt
    11401 atttttatgt agtattggtt ctttgatcgt gttgtatagt ttgaatccac attcgcaaag
    11461 gtatgatttg tatagtatgg tcacaggtct ttttctaaca ggattaggaa tctatttctt
    11521 catgaagggg aaaaaaagag aagaagcaaa ggagaaaaat aactaatgga aatcacgaaa
    11581 aaattaaata ttccagcatc gtttttttac gataaagtta tggactctgt ccttttcgat
    11641 gtacgtaaag cgaccggcaa atcagtaact agaaaacagc tgaaaaattt ggagtacgtc
    11701 aaacaattct cgcaaaataa ccgggctcgc ataaaaatcg aagaagtcat tgaaaaccag
    11761 tcttataagt ttcgtacatc gacaacgaag aatgaattcg tcgttcatta tcaaatcaaa
    11821 ccattggacg attcgacctg tgaggttcat tacacagaaa aaatggagtc ttatggcatg
    11881 cttcaaaagt tgaatgatat gcttttagga acaatcttga tgtattttaa acggagacgt
    11941 ttcaaaaaaa tgctagatat gatcgaagca acgtattaaa tcaatgaaac atggtattat
    12001 ttagttattg aaaaatgaag taagctagaa ggaatttttc ataggaagat agatctttcc
    12061 tgcgaatcct cactagcttt tttgtaggaa ggggcagcaa aatgacaaac aaagtaagag
    12121 agctaggtgt atcttcgatt gaggaaatgt ttgatttagc cacttatgca tttaatgggg
    12181 cagatacacc tgaaaggcga gaacgttttc gtacacttgc ggagaattct tggaattacg
    12241 gattttttga tgaggaggat cggctaacaa gtcaagtcat ggcgacccct tttccagtga
    12301 atttttacgg acaagagtac ctaatggccg gcattggcta tgttgcttct tatccagaag
    12361 caaggggaca aggcgggatc aatcagatca tggaaaagat ccttgaagat tgccgtgatc
    12421 gtaaagtaag cttatcttat ctggcgccat tctcctatcc cttctatcgg cgctatggct
    12481 atgaacaatc atttgataaa atcagttatc aactaaacag tcgtgatgtg ccgtttatca
    12541 aaaaaaaatc tggaaaaata aagcgtatgg attttgaaga tgcaaaagct gcaatcagaa
    12601 gaatttatga acagatgccg gaaaaccaac gagctggtct gaagcgcgaa gactggtggt
    12661 atacgtataa attcaagcaa aaaggcaatt accagtttgc tttgcatttt gatgataatg
    12721 aggaagcaac gggatatatc gtttatcagc ttgcaacgtc ttcctttatt attgcggagt
    12781 ggggattttt ggatcatgat gctttttgca gccttgttcg cttcgtaagt tctcacaatg
    12841 gtgcttttga aacatttgaa tattcatgcg gctacggcgg taatgatcaa aattatctat
    12901 tagaaaatcc atttgcttct gtaatgatca caccttatat gatggcgagg atcgtagata
    12961 tttctttgtt tttggaaaat tatccattta aaaagagaca agctgcattt gccctacaaa
    13021 tagaagaaga tcattatgcg aaatggaatg aaggaatcgt ggaagtaaca atcgaaaatg
    13081 gaaaaaatca tctctcaaaa gtagaacaaa caaaactccc aatcgttcga ggaagtatcc
    13141 aacatatcac gcagctatta ttagggtatc gtaaagtgga agagttggta ttccaagaaa
    13201 gaatacaggt gacaaaagaa tatgaagaaa cgttaagctc aatcttgcca cagcaacagc
    13261 caattcttaa tgactatttt tgataaaaaa cgggtgatga caatattttt gtcaccaccc
    13321 ttttgttttt catttggcat ttgaaggaaa atgttaaagt aaatcctctt ttttcgtaaa
    13381 tttgaatttt ttgttttctt ttgttttagg gttttctttt ttgtggtctt ggattgcttc
    13441 tttcgtaatc ttttcccgat tttttttaga tgaatctaag cgttctgcgt atactttttc
    13501 ttttggctta tcattcattg gaaaggacct ccctacatta tttcattcta cctctagttt
    13561 atcatctgtt aaggactagt ggaaacgttt tgcctaactt ataagctgat ttttttagca
    13621 gataagcttg caagtaaaaa acaaacaagc tacaattgat ttattgaaat tgttcctgta
    13681 gctcagtagg atagagcaat cgcctcctaa gcgataggtc gctggttcaa ttccagtcag
    13741 gaacgtacaa ataacccctg tatcctttgt ggtacagggg tttgttttgt atttgtgcca
    13801 aaaatgtgcc aaactagtta tcatttttat ataaactatc gaatacagca ttgatttttt
    13861 ctttatcctg atcttcaagt tctcgaacaa tatgaagata agtagacatt gtagtttcta
    13921 aactgctatg tcctaaccgt tttgatacgc taagtatatt tactccttga taaagtaaaa
    13981 tagatgcatg tgtatgcctt agtccatgca aagtaaattg cttttcaatc cctaattctt
    14041 ttaatttttt gcgcaaatat ttgctgacgg catttgatga aactaatcca ttttttaagt
    14101 tgaaaaaaac aaaattatga gggtttttaa cttcaaactt ctcgaataat tctttttgat
    14161 tgattttaaa cttttttaag agatcaatcg tatgtttatc aatggaaatt ttcctatttg
    14221 aagtttcgtt ttttgttttt ccccattcat ttaatttata attccatgtt ttattaattg
    14281 tgatgatttg atcttcgaaa tcgatatctt cccatgttaa tcctagaagt tcagcaaatc
    14341 gcattccagt agcaccagca actaacacga gcatagggga agagtactgt gcagaaaggt
    14401 tttcttctac aagtttcatt aaagatttaa attgatcata atctaaatat ttatcttctt
    14461 ttggcttcaa tgaatctttt cctttgatta ctgcttttct agttggatca aacggaatta
    14521 atccttcttc tacggcatct ttcaacgatg ctctaatatg gttattaaac ttaataacgg
    14581 tggattttac atggtctttc gcatacttat ttaaaaagcg ttgatatcca actctatcta
    14641 aatcagaaat caataccgct ggcatatatt tctttatgtt cattaacgta tcttcgtatt
    14701 ttctataagt gataggagat actgttcctt ctttataaag ttgcatccaa tcctcaaagt
    14761 aatctgataa taatagattt ttgcgatccc ctttaaggcc tttgtttagg ttatattcta
    14821 attcgttggc ggcatctttt gcttcgcctt ttgtcttgaa tcctgatttt cttatcttcg
    14881 tgtattttcc gtcatctttt ttgtatgaaa tttcgtattg ccaactattt ccacgtttga
    14941 ctaatcttgc cataattgaa tctactctct ttctctgata caataggcac tataaagaag
    15001 cctactgtat aggtttgttt tttcttagaa cacgctcgct ttggtcggtg gggcgtgttt
    15061 tattattttt tacttacttt actattaatc atatcccatt gagcatagga tttttctatg
    15121 ttcgatcctc ttgaactaat ttctcctgta aaagttactt tatcgccttt tgtaaaggta
    15181 tcagcattgt ttacgtcctt agcaaaaatt acatatgaaa ctttaggtgt tgtagaaata
    15241 tcactccaac ttttatcatc gtactctttg tctgctataa tggctattct agtagtcatt
    15301 gattcgataa cagttccttc aaaagtatat gttttaccac taatatattt agtaaaagct
    15361 gtattttgct cagtagctgg agtaatagaa taataactat ctaagaaagc accccagtca
    15421 tgattatttg cctctaaaaa ttcttcaaat tgagttaggc ttttattgct gctgttagat
    15481 gtagtagttt gagtctcaga tgatgagctt tcctgtttgt tattgtcatt tgcctcgttt
    15541 gatgaggaaa gtgagaaacc tacggcagta aaaataatcc cgataataag gagaatcata
    15601 ggtgttttct tatttgtttt tttgataaat cttacaatca acatgattaa acctataaaa
    15661 aataaaacaa taccagtaaa accgaatata ccgtccatta ataaaacatc cttttctttt
    15721 gatagttaat attacaaacc aagcagttct tttttcttaa aatcaaattc gtcctgatta
    15781 ataatacctt catccaacaa ctctttatac tttttaattt catctgcact tgaaatttgt
    15841 gtttctttgg aattattatc taatatagat tgttgcttct ctatatattt ttttaaattc
    15901 tccatttcat tccaatattt ttttgtaaac ataatggtgt tttcatcttt cgtggctgct
    15961 aatattcctc cacgactttc gtttccaccc agcagagtaa attgtatata accattgctc
    16021 atacctggtt tttttaattg tactgctgat atatttttaa agggaatagt tttttctcct
    16081 ttaatacctt gattaactaa atttataaat ccttttctaa taattgaaat agaatcatca
    16141 gttactttga tcaaggtttt tcctggagat tttattaaaa tctctttttc cattttttct
    16201 tcctcatttc tatgatatga tttttttgta gaagctcata tatgaggaaa gagtccgtgt
    16261 tgcagcacgg gcttttttat ataagaaaac gataagcgct ttctggaagt ccgtaaagat
    16321 tttttaattc ctcaattcgt ttaggatatt gatcgttgtc ttctttgtat agagaaacaa
    16381 tgagattagc agcaaaacaa ttagcttcgc tttcagattt gcttctagat gttcttgtcg
    16441 atacatagta actggataag ccacgatgaa aaatagcgtg acctaattcg tgagcgcaaa
    16501 tgtagaatct ttcctcagag tctcgcagtt catcatttaa aaagattatt gcacgatctc
    16561 taatttcttg aaactgccct ttgggatttt cgataaaagg aacgtattga attttaatgc
    16621 ccatcttttc acaaatataa aaaggattag cggactggta tttccgcttc aactcctcga
    16681 ctaaattaat cgtatccatc tccataagct cacatctttt tgcctttttc tttgtcttct
    16741 ttcacaatat cccagaaagt cgctataagg atatctttta cgcgctgtat ttgttcgggt
    16801 gtcaatgttt ccccaccata agacatatta acatttgagt ctagtagttt atcaagttca
    16861 accacttcct cttttgtagc ccatttggga acattattat ttcccaataa ataatcagtt
    16921 gtgaccccaa aataatcagc aactttcttt aagttctcag attttggtga ggctttatcc
    16981 catcttctta tttgtccatt agaaatgcct acctgtcttt ctacttctgc tatagtcaca
    17041 tgcttttcat ctgctaattc tttaatctta gtaactaaac tcattattat caacctttca
    17101 aagctgaaaa gaaaataaat agcttaaaag ttatattttt agttgacaat tagcttttaa
    17161 gctagtatat ttaatttgta agctaaattg ttagctaaat aagagcaaca aaaatatcta
    17221 ttaattaaaa acattctctc ggtcgccaaa cttagaaatg ttattttaga ggctttttat
    17281 aaggcttatt taactatgta tttataatag cttaaaagct aataggtgtc aatgatttag
    17341 ctaatttttt agcttacaaa tcatttttta gaaaggagct gtttttatgt ctgagaattt
    17401 agacttaaaa attcgggcag agatgagaaa aagaagaatg actttcaaag aactagctgc
    17461 gcttgttggt atttcaggag cttatttatc agatattcta aacggcaatc gtgatggaaa
    17521 aaaagctcaa gaacacatag aaactgtaaa aaaaatatta ggtattcaat aggaggaaca
    17581 gctaatgcaa tatctagaag caaaaattcc aattccagaa ggctatgtaa ttatctccca
    17641 agtggattat gaggagttaa aaaaagctga tgatactggt agatggatga cgttgccaga
    17701 agtactagaa cggattaaca gaaaatatga ttggtttact tctagagttt taaagaaccc
    17761 aagatataga aatattatcg atatcgaaaa aaacaaaaat ggatttgtct attatccagt
    17821 tgaaggaaga gacacatatc tatttttaag aagtaaaaca cttgaatttt tagaaacaaa
    17881 tttttcggaa atcttaagga ggcaagcgga tgggaaaatt taatagagca ctagtattca
    17941 gcgcaccgct aatcatctac gctttaggac tttggggaag cagacaagcg ttgataggaa
    18001 cgattgttta catggtttgg atttttatgg ggctggatga agctgagtac aaaacaaaaa
    18061 agccagtcgg gagggactga ctaatgaaaa aaagtttaat gactataaac gaaaaacaat
    18121 tgaaagaaaa ttttaatgat ctcatcaaag aatttgtaaa agaaactgga gaatttccta
    18181 atcaaattca tctagttgcg gaggggcata gccagtatca agctgtgaaa tttgagatga
    18241 agaaacaaat ctattgattt ttaattaatt ataccaaaag gagagaagaa ataatgcaag
    18301 aattagtaat tttgaaaaat aaagaagctg tgactacgag cttgcaagta gctgaagctt
    18361 tcgaaaagaa acataagcat gtgctagaag caattgaatc agtaaaaaga tcggtcgaaa
    18421 attcggccaa tgttgaagat gtgctcaatt ttgagcagat gtttgtagaa ggaaacgagc
    18481 cggacacgta tgggagaagt cggagagttt ttttcatgaa tagagatgga ttttccttgt
    18541 tagctatggg attcactgga agtaaagcaa taagtttcaa actcaaattt attgaagcat
    18601 tcaacgagat ggaagatgtc attcgtaaaa atactgttcc tcaaacgatt gaagacatga
    18661 tgatctacca actagaagaa atgaaagatg ttaaaaaaga tgtctccatg cttaaagata
    18721 ctatgcgaat tagcggacaa caagagtttg aaattaagca aaaaggaaat atgaaagtta
    18781 tggaagtttt aggaggtaaa gaaagccgag cttatgaaga aatcagcaaa aaagtattct
    18841 cgaaattttg gtctgaattt aaacgtacct tttcaatccc aagatatggc gagttacctc
    18901 gtaagagatt cgatgatgct gtttcattta ttgaaatgtg gttgccagaa actgcgatcc
    18961 gtatggaaat tgatcaactg aacagacaac agagactttt tggtgatgaa aatgaataga
    19021 gctgaagcgc taagaatagg gacggtaatt gctaatcgtt ggtggagaca caataaacca
    19081 agcatcctaa gccaacaaca tattgataag caaaaagcat ggcaacaaat aaaaaagtga
    19141 ctcagccgac caaagcaatg agtcacaaag aaaatacatc taaggagatg ttaccacatg
    19201 aaaaaagaac tttccactct agatcaatat ttgactgatc ctagttgggg caaatcgaat
    19261 gtcaaggaaa caaataatcg aaaaatcaga cgtaatcttc tgacagatga agaactagca
    19321 tgtgatcaag atgatttggg caattttgtg agcatttggg atcatgttta ccttattcat
    19381 ctatcaaaac attcaaacaa acctgaatac atttatgtca tcgaagatgg cttgactgat
    19441 gcattagaag agta
//
LOCUS       DADVXB010000047        19187 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.048, whole genome shotgun sequence.
ACCESSION   DADVXB010000047 DADVXB010000000
VERSION     DADVXB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.048"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(42..2492)
                     /gene="parC"
                     /locus_tag="KB902_001268"
     CDS             complement(42..2492)
                     /gene="parC"
                     /locus_tag="KB902_001268"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBB6808107.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(2504..4549)
                     /gene="parE"
                     /locus_tag="KB902_001269"
     CDS             complement(2504..4549)
                     /gene="parE"
                     /locus_tag="KB902_001269"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBB6808108.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(4715..5149)
                     /locus_tag="KB902_001270"
     CDS             complement(4715..5149)
                     /locus_tag="KB902_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBB6808109.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5276..5914
                     /gene="plsY"
                     /locus_tag="KB902_001271"
     CDS             5276..5914
                     /gene="plsY"
                     /locus_tag="KB902_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBB6808110.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(6046..6921)
                     /locus_tag="KB902_001272"
     CDS             complement(6046..6921)
                     /locus_tag="KB902_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6808111.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(7003..7794)
                     /gene="codY"
                     /locus_tag="KB902_001273"
     CDS             complement(7003..7794)
                     /gene="codY"
                     /locus_tag="KB902_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBB6808112.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(7812..9212)
                     /gene="hslU"
                     /locus_tag="KB902_001274"
     CDS             complement(7812..9212)
                     /gene="hslU"
                     /locus_tag="KB902_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBB6808113.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(9226..9774)
                     /gene="hslV"
                     /locus_tag="KB902_001275"
     CDS             complement(9226..9774)
                     /gene="hslV"
                     /locus_tag="KB902_001275"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBB6808114.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(9811..10716)
                     /gene="xerC"
                     /locus_tag="KB902_001276"
     CDS             complement(9811..10716)
                     /gene="xerC"
                     /locus_tag="KB902_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBB6808115.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(10914..12290)
                     /gene="trmFO"
                     /locus_tag="KB902_001277"
     CDS             complement(10914..12290)
                     /gene="trmFO"
                     /locus_tag="KB902_001277"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBB6808116.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(12259..14337)
                     /gene="topA"
                     /locus_tag="KB902_001278"
     CDS             complement(12259..14337)
                     /gene="topA"
                     /locus_tag="KB902_001278"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBB6808117.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(14459..15316)
                     /gene="dprA"
                     /locus_tag="KB902_001279"
     CDS             complement(14459..15316)
                     /gene="dprA"
                     /locus_tag="KB902_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBB6808118.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(15372..16139)
                     /locus_tag="KB902_001280"
     CDS             complement(15372..16139)
                     /locus_tag="KB902_001280"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBB6808119.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(16132..16992)
                     /gene="ylqF"
                     /locus_tag="KB902_001281"
     CDS             complement(16132..16992)
                     /gene="ylqF"
                     /locus_tag="KB902_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBB6808120.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            17252..17650
                     /locus_tag="KB902_001282"
     CDS             17252..17650
                     /locus_tag="KB902_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6808121.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            17929..18429
                     /locus_tag="KB902_001283"
     CDS             17929..18429
                     /locus_tag="KB902_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6808122.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(18512..19063)
                     /gene="lepB"
                     /locus_tag="KB902_001284"
     CDS             complement(18512..19063)
                     /gene="lepB"
                     /locus_tag="KB902_001284"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6808123.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
BASE COUNT         5010 a         4158 c         3327 g         6692 t
ORIGIN      
        1 attaatacag atggcgtctc ttcattaaaa tactacaaca gttacgactc gatgaaaatc
       61 tcaggagcat cgataacttc gatgacttct ccaccttttt tctcatccat cgcaaatgat
      121 ccattcgatg ttcgatcacc tatagggaaa tcagttgggt caatcgttaa ctgctgccct
      181 ttttgattca tcaaggttat ttcttttgat cttccttccg acatatagat aatacggtgc
      241 ggattttttt tcagctcacg catgaccgtc actccccgct tcgcacgtga agtttggctg
      301 atttcttgag caagcatgcg tttaacagct cctcgctgag taacgattac gatcggcgta
      361 tcaccttctg ctaacacaag cagcccgttg ataatcctat ctccatcttt caaattcata
      421 gacttcactc cagctgcctt tgctccaaca acgggaacat ctgttaaagg atagcgcaaa
      481 cccattcctt gatgcgttac taagaaaaca tctaagcctg gctgatcttc tttcagatac
      541 acagcaatca gttcatcttc ttccgccttt agcttcatac agctgagcgg acggctctta
      601 taggtgcgcc atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc attcttgctg
      661 atgaatacaa atgttttctc tgcttgaatt ttttgatatg ggaaaacagc taaaatcgat
      721 tcgtctacag acagattgga gattgtttga gaaatgtgct caccagcatc tttccatttc
      781 aaatcgggta gttcatggac agggcggtag atcacatttg ctttatttgt gatcagaaga
      841 acatggtcca atgtactcaa ttcacctgag tatagcaagt agtcgccttc tcgcatcccg
      901 atttcttctg gtttggaagc actataagaa cgaaggcttg ttcgcttcac atagccttct
      961 cgcgtcacac tgacaattac gtcttcttgt gccactaaga cttgcgtatc aattttgatt
     1021 tcttcgattt cgtcttcgat tgtcgttaga cgagcggaag aataattttt tttcacttct
     1081 cgcaattctt ttttcataac agagaaaagc tctttgtcat ttgaaaggat tttattcaac
     1141 tctgtgattt gcgcaatcaa gctttcggat tccttttgaa gctctgtgat atccgtgttc
     1201 gtcaaacggt ataattgcaa tgtgacaatt gcttctgctt gttcttctgt aaattgaaag
     1261 acgtcgacta aattcttttt ggcgtctttt ttgtctttac tttcacgaat cgttgcgatt
     1321 acttcatcca gaatcgataa agctttcatc aatccttcta cgatatgctg tcttttttga
     1381 gctttggcta aatcgaattg actacgtttt gttatgactt gctttcgatg ctcgatataa
     1441 cttcttaaaa tgtctttcag tccaacttga tgcggagtca tatggtcgat agcgaccata
     1501 ttgaaattgt aattgatctg tagctcagtg tttttgaaca aataattcaa aattccttga
     1561 gcattggcgt cttttttcaa ttcgacgaca atttgcagac ctgttctatc actttcatct
     1621 cgtacttcag ctattccatc gattttctta ttcaaacgga tctcatccat ttttttcacc
     1681 aaggtcgctt tatttacttc atatgggatt tctgtgatca cgatttgctg tttattaccc
     1741 ttcattgcct ctatctttgt tttcgaacga agaataactt ttcctcgtcc tgtttcataa
     1801 gcttttttga tttcatcttt tccttgcaag atccctcctg ttggaaagtc aggtccagga
     1861 atatattcca tcaatttttc aaggctcgct tgtggatgat cgatcatata gattgtgcca
     1921 tcgatcactt cagctaagtt atgagtcggg atttctgttg catatccagc agatatacct
     1981 gtcgatccat tgacgagaag gtttgggtat cgagctggaa ggactgttgg ttctttttct
     2041 gtatcatcaa aattccacac gagatcgact gtttctttct cgatatctgc tagcatctct
     2101 ccacttaact tggataatct ggcttcagta taacgcatcg cagcaggtgg atcaccgtcc
     2161 atactcccgt tattcccgtg catttcgatc agtacttccc gcaacttcca gtcttggctc
     2221 atgcggacca tcgcttcata aatactgatg tcaccatgag gatgataatt ccccatgata
     2281 tttccgacag attttgctga tttacggaat cctttgtcat acgtattgcc atctttgttc
     2341 atggcaaata atatccggcg ttgcactggc ttcaatccat cacggatatc aggcagtgca
     2401 cgttcttgga taatatattt ggaataacgt ccgaagcggt cacccatcac ttcttctaaa
     2461 gttaattctt gtacttcttg tcgattttcc atcaggtgac ctcctattct acttcaaata
     2521 actgattgtt ttcattttta tctgctcgtt cttcatctaa taaatcatta gaaactgaag
     2581 gagagatttc agtatcctct tttttatcta agatactgcc atcttcttcg agcgtaaatt
     2641 gcacgtgatt ttcgatccat tttcttcgag gttctacttt gtcacccatc agtgtggtta
     2701 ctcgacgttc agcttgcgca gcatcatcga tacggacgcg gatcaacgta cgggaagtcg
     2761 gatccatcgt tgtttcccac aattgttccg cattcatctc tccaagtcct ttatatcgct
     2821 gcagcatata tcctttgccg acttttttaa tcattgctgc caattcgtca tctgtccacg
     2881 catattcaat gacttgcttc tttccttgtc ctttggatac tttatataaa ggcggtaacg
     2941 cgatatatac tttcccagct tcaatcagcg gtttcatata acgataaaag aaagtaagca
     3001 gtaatacttg aatatgggcg ccgtctgtat ccgcatcggt catgatgatt actttgtcgt
     3061 aattacagtc ttcgatagaa aactcaggac cgactcctgc accaatcgta tagatcatcg
     3121 tattgatttc ttcatttttc aagatatctt gcattttagc tttttcggta ttgatgactt
     3181 ttcctcgtaa aggtagaatt gcttggaact ttctgtctct tccttgttta gcagatccgc
     3241 cagcagaatc cccttcgact aaatacaatt catttttctt agggtttcgg gattgtgcgg
     3301 gtgtcaattt tcctgaaaga agagattcgc cttttttacg cttcttccca tttcggcttt
     3361 cttctctggc tttacgtgct gcttctctcg cttctctggc tttgattgct ttacggacca
     3421 acatctggct catttcgcta ttttcctgca aataaaagcc catttgttca ctgatgacgt
     3481 tatctactac ggtacgagca actggcgtac caagtttttc ttttgtttgc ccttcaaatt
     3541 gcagaagatt ttcaggtaca cggatagaaa gtacagcagc taacccttct ctgaaatcac
     3601 taccttccag attcttgtcc cgttctttca gcaaaccaac ttttctcgca tattcattat
     3661 aagatttcgt catcgccgct ttcataccag cttcatgggt tcccccatct tttgtccgaa
     3721 cgttattgac aaaagataaa acattttctg aataaccgtc attgtattga taagcgacct
     3781 ctacttcgat accttctttt tctcctgaaa aataaacaac tggtgtcaat gtatcttttt
     3841 cttcattcag ataatcaaca aattctttga ttccttcttc gtaatgaaaa atttccttga
     3901 ctggttcttc tccacgaaga tcagaaagag agattttaac gccttttaga agaaaggcag
     3961 attctcttaa ccgttcggct aaaatttcat atgaaaattt cgttgtactg aatattgtat
     4021 catctggtaa aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct atctttttca
     4081 aagtaccgtc aggtttaccg ccgtttttaa atttctgctg atactctacg ccatctctaa
     4141 cgatcgttac aattagccat ttcgataagg catttaccac actggctcct acaccgtgca
     4201 gtccaccaga agttttgtac cctccttgac caaactttcc gccagcatgc agcacagtaa
     4261 aaatcacttc aactgttggt attccggaag catgcattcc tacaggcatc ccacgtccgc
     4321 tatctgcaac agttatacta ttgtcttcat ggatggtcac atcaatctca ctgccataac
     4381 ctgataatgc ttcgtcaact gcattatcga cgatttcata gactaaatga tgcaagcctc
     4441 ggctgtcagt ggatccaatg tacatccctg gtctttttct aactgcctct aatccttcca
     4501 atacttggat ggacgagtca ttgtattcgt tgtttacttt ttttgccaag gcaaacgctc
     4561 cttcaataat actttgcggc aaaaccgcac cacgattatc atactagaaa aggtcgtgaa
     4621 aaaaaagagg gtagacgaga aatcaatttt aattatctcc taaccgcttt ttcgacattc
     4681 ccctctatcg atcatctctt ctttgtggtc atttttattt ttggttttct ttcaacttac
     4741 caagttcaat cttaatacaa cgatccatta cgatatctgt acgtcctgct tttcttagca
     4801 tctcagctgc ttctttgttt tcaatcccta attgtgccca gaacacttta gcatcagttt
     4861 tcaaaaaatc acctgctatt tcaggtaaaa attcactccg tctaaataca tctacgatat
     4921 cgattggatc atcgatttct gtcaaattcg catagacttt ctcgcctaga atttcttcac
     4981 cagccaataa tggatttact ggtatgattt tatatccatt gtcttgcaat acctgtgcaa
     5041 ccatgtaact tgttcgttct ggtttattgc tcaagcctac gacggcaata ttttttgctt
     5101 cttccaaata gttgaaaatc gtttcttgtg ttggattttt tacagacatt tctgccaccc
     5161 cttgcttttc tttttattcc atctattata cttgtatctt tcattttttc aattgttcct
     5221 gttacctatt catgctaaaa taaaggatag ttttcaactt gaaagagggt aaaaaatgaa
     5281 attgatctta ttacttattt tagcatatct tttaggttct attccttccg gtgtctggat
     5341 tggcaaattg tttttcaaaa aagatatccg acaacacggg agcggtaata ctggaacgac
     5401 caatacattt cgtgtattag gcaaaacagc cgggattgtt gtcctgctta tggatatttt
     5461 aaaaggtaca ttggctactt gtttgccgat gatcttccac ctttctggga ttaaccctct
     5521 ttggtttggg gtatgcgcca ttcttggcca tacatttccg atttttgctg ggttcaaagg
     5581 aggaaaagct gttgcgacaa gtgcaggaat gcttttagga tttaatcctg tattttttgt
     5641 ttattcttgt atcatcttta tcgttagttt attttgtaca agtatggtga gtttgagcag
     5701 tatgatcagt gcagtattga tcactttatc tacgatcgtc cttccttatg tagctcctgt
     5761 gattttggct aagcccaatt ggttactgac gatcattgcc tttttagttt cttcctttat
     5821 cttttatcgg cataaagaca atatcaagcg tatcagaaac catactgaaa gtcgaatccc
     5881 gtttggtttg aatagcagca agaaaaaatc ctgatacttt ttcattccaa agagataaaa
     5941 cgggagtgtg acaaatcgat gtcacactcc cttattactt acaggatagc ttttttacac
     6001 accttggtaa acggtgttcc ctgctaactt ctcggtcaca acctcttact tcactgtgat
     6061 ggaatatttt gtcttgaaga tttcatgggc acctagttga ttgatcccta ctttttccat
     6121 caagtttcca ctactgttca ccgtgtcagc gattccgcac cacggttcga tacaaacgaa
     6181 aggcgcttct tttggataag gagaccagat ccctacataa ggcatatctt tatagcttaa
     6241 agttacgcta tgggaagatt tttcacttcg aatggcgtac gcatttagac cccttgtttc
     6301 aaaaaccaag gcatcttgct caaaaagttc acgattcaaa gccagattcg tatttgtctg
     6361 acctaacgtc ttttgatcca tatcgatgaa tgggcctttc aatggtaggc gtaatcttga
     6421 tttcaatgga gaaaatgcca gatagaaatc ttcaaatgac aatccttctt caagaggtac
     6481 attgaaagca ggatgtccac cgatagaaaa gaacatttct ttttcaccgg tatttgccac
     6541 ttgataatga accgtgatgc cgtctcctcc taattcatag ctgatcacta attcaaaatc
     6601 aaatggatac ttttctaatg tctccggcgt actccttaag atgaaactag ccatttcttg
     6661 tccatgttca atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc ccatttgata
     6721 tgttttccct tgataaacat actgatcatc ttttaaacgt ccaacaaaag ggaataaaac
     6781 cggtgcatgt ctgccccaat acgctggatc accttgccag atatactcta aaccatgttc
     6841 ttttgatttc agactgatca attccgcacc gtgttcagcg atttcggcga tcagctggtc
     6901 attttgaata ataacagtca ttgccattcc tccaacttcg acttactttt taaaatggga
     6961 aggctggaac aaacatttct atctgcccca gtccccttac ttctaataac tgtgttttgc
     7021 taactcgtct ttaaaacggg aattcaatac ttttaaataa gttcccttca tgcctaacga
     7081 acgagattca atgattccag ctgattccaa ttttcgtaaa gcattgacga tcacagaacg
     7141 agtgatgccg atactatcgg caatattaga agcagtcaga cgaccttcat ctccatccaa
     7201 tgcttcaaag atagcttgta cagccttcaa ttcgctataa gataatgtgt tgattgccat
     7261 ttggacagcc gttgcactcc gtacatctgc ttcgatgctt cgagacttct gataaaggat
     7321 ctgcataccg acaaccgtag ctccatattc tgctaagact agatcgtcat ctgcaaacga
     7381 ttgttccata cgagataaga taatcgtacc caaacgttcg ccagctccaa agatcggaac
     7441 gacagtcgtc agaccaaatg gatatttctc tcttgactct accggaaatg cagtaatatc
     7501 actagtaatt gggatattag cttcagtttt catcaactgt gccactgtat cagtataaga
     7561 ttcaggaaat tgtttctcaa caaacattgt tttgattcgt tcattgttca catcgtgacg
     7621 ttcattataa cctagtaata ctccgtcact tcctatgata taggtgttgc tgtcaagaat
     7681 accacctagt gtgacagcca ttttatcgta aggcaaatct gcttgcatgt caaaagtatt
     7741 cttttgctgc aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg tcattgtcgt
     7801 cctccgattt tttataaaat atagcgactt aaatcttcat ttgccgcaat tgagccaagt
     7861 ttgtcatcca catatgcttc tgtgatcgtt atttctccca tttgcatatc tggtgcttca
     7921 aataatagat cttctagtag tttttccaaa atggtatgca gtctgcgtgc gccgatatta
     7981 tctgtgtcac ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc ttcttttgta
     8041 aacgtaactg acacattttc tgtaccgatc aacgcgacgt attgttttac taaagcatta
     8101 tttggttcgg tcagaatctt cacaaaatct tcagctgtca aatcatctaa ttctacccgt
     8161 atcgggaagc gtccttgaag ttctggaatt agatcacttg gtttagacaa atggaaagct
     8221 cctgaagcaa tgaataggac gtgatctgtt tggatgatcc cgtattttgt gtttacttgt
     8281 gaaccttcga caattggcaa tatgtctctt tggacgcctt ctctggatac ttctccagat
     8341 tgctgtgatt tagaagtgat cttatcgatt tcatcgataa aaataattcc actttcttcc
     8401 gctaatttga ttgcctcact atggatatca gcatccttga ctaattttgc tgattcttcc
     8461 ttgatcaata actctaaagc ttctttgact gttaccgtcc gttccacttt tttcttcggt
     8521 gtcaaagcac ctagagtttc atttaggtcg atccccattt gctccaatcc attgttcatc
     8581 attggtgcag gtttcttttg gtcttcaact tcaatggtta cttcacgact atccagtaaa
     8641 cccttttgta gttgttccaa gactgtacgg cgattgattc gaatatcttc tgtcacttct
     8701 tcttgcggtt cagcggtatt ttgctgacta gcattaaaaa gattcatcat ttgttcaaat
     8761 tgattagtgg attgtttctg ttcttttttg ataccaggta ccaagatttt taccaaacgt
     8821 ttttctgcat tttttttagc acttgtgtat acacggctgt actgctcttt ttctacgatt
     8881 tggatcgcat tttctactaa atcccgaacc attgattcta catctcttcc gacataaccg
     8941 acttcagtaa attttgttgc ttcgactttg acaaatggtg cattgacgat ttttgccaaa
     9001 cgtcgtgcga tttctgtttt accgacccct gtaggtccga tcatcagcat attttttggt
     9061 gtaatatctt gttgcatttt ttcatctaac tgcaaacggc gatagcggtt acgcaaagca
     9121 acggcaacag atttttttgc tgcgtgctgt cctacgatat attcatctaa ttcacttacg
     9181 atttgtcttg gtgtttgttt taattcatac atatctactc acctcttaca gttcttctac
     9241 gataatatta tgattagtaa agatacagat atctgcggca atatttaacg cattttctgc
     9301 aatttctttc gcactcatgt cgttttgagc atagtttttc attgctcggg ctgcagccaa
     9361 cgcaaaattc cctcctgatc cgatagctaa gataccatca tctggtgtga taacttctcc
     9421 tgtacctgaa acaagaagca tttctttatc attcattacg atcagcatcg cttcaagttt
     9481 ttgcatagat tgctgtgtcc gccattcttg agctaattcg acagctgcgc gttgtagatt
     9541 cccgttatat tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg catctgcaac
     9601 acttccggcg aaacctacaa caacttctcc attgtagata cgtcgtactt tctttgcagt
     9661 gcctttcatg acaacagatt cacccattgt tacttggcca tctccagcca tagcaaattt
     9721 cccgtctttt tcgacggcac agatagtggt tgaatgaaat ggtgattcga ccatgtttgt
     9781 ttcctcctaa atttgttctt ttccttattt ttacgctctt ggatggaaag aacgatagtt
     9841 tttttgtaaa ctttcttttg ttacatgggc atagatctgg gtagtcgata aattggcatg
     9901 tcctagcaat tcttggactg tccgcaaatc tgccccatta tttaataaat gagtagcaaa
     9961 tgtatggcgc agcatgtgag gatggatatc actatccaaa ctgctttttt tgatcatttg
    10021 attcaagaca tattcaattc cagtaggcgt gattggtttt ccatgatgat tcacaaaaac
    10081 gatatcatgc tcttcgtgat attttgtcat caatacctgg cggccttccc tgaaatattc
    10141 ttgcagagca tcttgagcaa aagaacctag aggagcatat ctctctttgt tccctttacc
    10201 atggatcaac atgacctctg aatcaaaatc aatgtctgat accgacaaac tgctacactc
    10261 acttaaacgg atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc tcaaatccaa
    10321 aggactatct cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat aaaaaaaacg
    10381 tggcagtctc aaatttttct ttttgagatg aacgtaagaa aatggatttt cttttatcac
    10441 ttcttctttg agaagatact gataaaacga acgtaggctg gctatcttgc gactgataga
    10501 atttctgcta tagctaggac gatgatcagc taatgcactc aaatagacac gaaccgtaaa
    10561 atattccgcc ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt tgaaatggag
    10621 aatgtcttct tcatatgctt ctttcgtttt ttctgaatat cctctttcga caatcaaata
    10681 acgcaaaaat ttttgttccc acgtggcttc tgtcattttc tcaccttcct tttgtcccag
    10741 agaataattt agcacagcgt ttataaaaag acaaataaat tgtcagaatt taaccaatat
    10801 ttctaagttt gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa ttcttaagaa
    10861 aaacgcaaga aaaagagcga gactatccgt ctcaccctct tcatggagtt tccttactca
    10921 tttgggattg cagttttttc taattctgtt tttattgcct cattagcttt taaagctcgt
    10981 tgtgcaattg cttcatatct tgcttttttg tctcgaatgc gctctggcag ttcaggaaac
    11041 agaccatagt tggcattcat cggttggaaa tgttttcctt ccgcatgagt aatgtagtaa
    11101 gccatacttc caatagctgt ttcttgtgga aactcgactg gttccatttc ttttgctaag
    11161 cgtgcggcgt tgattccagc aagtagtccg ctcgctgcac tttcaacata gccttctaca
    11221 ccagtcatct gacctgcaaa gaacagatct tcgcgtttcg ttgattggta agtcggtttc
    11281 agcaattctg gcgaattcat aaagctgttt cggtgcatca caccatagcg aacgaattca
    11341 gcattttcta acccaggaat catccggaaa acacgttttt gctcgcccca tttcaagtga
    11401 gtctgaaagc ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg cagctggata
    11461 acagcataag gacgtttgcc agttttagga tcttccaatc caactggttt cataggtccg
    11521 aaaagcatcg ttttgaatcc tcgctgtgcc attacttcaa ttggcataca tccttcaaaa
    11581 tatttttctt tctcaaaaga tttaagttct gccacttcgg cattgattag tgcctcatgg
    11641 aaagctttga attcctcttc tgtcatcgga cagttcaagt aagctgcttc tcctttgtca
    11701 tagcgggact tcaaatatac tttatccata tcgatcgtag ctttgtctac gattggtgca
    11761 gctgcatcat agaaataaaa accatctgaa ccattgaatg ctttgatgct ttctgctaat
    11821 ggatgagaag tcaaaggtcc tgttgctact acggtgattc cttccggtat ttcagtaatt
    11881 tcttcgttta tcactgttac taatggatgc tctttgactt ttcgggtaat tgtttcagaa
    11941 aaagaatcgc ggtcaacagc taaggcacca ccagctggca ctgctgtttc atctgccgaa
    12001 gtgattacta ccgaattcaa tcggcgcatt tcttctttca ataaccctac tgcattagcc
    12061 aaactgtttc ctcttaatga attggaacat actagttcag caaaattact tgtgtgatgc
    12121 gcctcagtcg atttgactgg acgcatttca tataaacgga cagggactcc tgcttgtgcg
    12181 atctgccaag cagcttcact tccggcaagc cctgctccaa caacatttac cattttcaat
    12241 gaaagaacct cttttctatt atttttggat gtcttcttcg taatctccat ttacacagac
    12301 tacttgttta ccgcctttga ctttcttctc gaccagatat ccgtcacatt ttggacaatt
    12361 tctgcccact ggtttatccc aagaagtgaa ttcacattct gggaaacggg aacaaccata
    12421 gaatagtctg tttttcttag attttcgttc aatgacttgt ccttcatgac atactgggca
    12481 agtcacaccg atttctttta cgattggttt cgtattccga caatcaggaa aattactgca
    12541 agcataaaac ttcccatatt tccctaattt tatcaccatc ggatgtccac agacatcaca
    12601 atcgaatcct gctggttcat ctttgatttg aattttttcg attttttctt ccgcattcgt
    12661 cagttctttt tcaaacggtt tatagaaacg atcaaccact ttgacccacg cttccgtgcc
    12721 ttcttcaatt ttatccaaat ctccttccat ttctgctgtg aaatggatat cgacgatttg
    12781 agggaagaat tcacagatta atgaattgac aatttctcct agttcagtcg gctcaaatct
    12841 tttttgtgtc aattttacat agtagcgtct ttggatcgta tcaagtgttg gtgcataagt
    12901 ggaaggtcgc cctaccccgt tttcttctag tgcacgaatc aacgtagcct cactaaaacg
    12961 tgctggtggt tgagtaaaat gttgttttgg ttcaatatca acagattgga ctacatcgcc
    13021 ttcttcaagt tctggaagaa tattttcttt ctcttctttg ccgtcatctc taccttccac
    13081 atacacttgc atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga agatgacacc
    13141 attttgttct aatgtcactt tcattgtatc taaaatagct ggtgtcatct gactagccac
    13201 aaaacgtgac cagatcaatg tataaagttt caattgatct ttatctaaat attgtttgag
    13261 ttcatctggt gtacgaagca cactcgttgg acgcacagct tcatgggcat cttgtgcgcc
    13321 ttgagcattt ttgatctttc ggtgatcatg tctagaaaat tcttttccat acgtatcttc
    13381 aataaatgct gcggcctctg cttttgctgt atcggcaatc cgggtagaat cagtacgcat
    13441 gtatgtaatc aagccgactg ttccttgttt acccaaagtg attccttcat ataattgctg
    13501 tgctaccatc atggtttttc ttgttcgaaa gtttaactta cgggcagctt cttgttgcag
    13561 gctacttgta gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt ctactttttt
    13621 aacttcgaag tctgttccat caattctagc agtgacttct tttacacttt gtgcatctgg
    13681 taatttcttt ttcttaccgt cgattcccca gaaatttgct ttgaatttct tgcgagcttt
    13741 tttaaaatta ccgtcgatgc tccaatattc ttctggaaca aattctcgga tctctttttc
    13801 acggtcaata ataattttta aagcgacaga ttggacacgt cctgcactta accctttctt
    13861 gaccttacgc cagagaatag gactgatcga ataaccaacg attctgtcta aggtacgacg
    13921 agcttgctgt gcatctacta aatctacatc gatcgttctt ggttccttaa aagctgcttt
    13981 gactgcgtct tttgtgattt cattgaagac cacccgattt ttttctttca gatccaaccc
    14041 aagtaggtac gctaaatgcc aagcaatcgc ttctccttct ctatccgggt cacttgccaa
    14101 gtaaactttt tgagcttttt ttgctgcggc tttcaggctt ttgatgacat cgccttttcc
    14161 gcgtatagaa atataatggg gttcataatt gttttcaaaa tcgataccca ttttactttt
    14221 cggtaaatct cttatatggc caacactggc cattacttta tagtttcgtc caagatattt
    14281 ctcaattgtc ttggcttttg caggtgattc tacaatcact aaatatttat acgccattac
    14341 tgaatggact cctttccatt gtcgtgttcc tactattaaa agaggattca tacaaatcgt
    14401 agctaatcat atccattcag aaaacgtttg tcaagaaaag caaatgaaaa gtatggtgtt
    14461 attctttaaa ttctgccaag atatcttcac ccgaaaccgt gcaaactgca ccgtcttgga
    14521 tcaaatgatg acatccggta gaatgttctg ttaaaatatt tcctggaaca gaaaaaactg
    14581 ttcttccaag atccaatgct tgctgtgctg ttatcagaga gccgcttttt ttcttggctt
    14641 caaagacaca tgttccttta gacaaagctg cgataatccg atttctcatt ggaaaacaat
    14701 gctttttcgg gccggattga ggaggatatt cactcaaaag aagatgatca tttgcaatca
    14761 cctcttgcaa gtcacgattt tcagcaggat agacttgctc tatccctgtt ccaatgactg
    14821 cgattgtccg tccaccatga gagattgctg cttggtgacc gtatgtatct atccctttcg
    14881 cgcagccact gacgatcaca tatccagctt ctatcactgg ttttagtaaa taataaactg
    14941 tttttttggc taaagcagaa gtgtgtcttc caccaacaac gcttaacatg ttacaagaaa
    15001 gtaaagatag atcaccatta taaaacagta caattggcgg ataggtcaag tgaagcagct
    15061 gagggggata tttgggatca aagcaagtga taaacgactg tttcgattgg attttgcccc
    15121 agttagcgtg aatttcctgc caacttttgc gaaacagctc ccggtgtttg gttattttac
    15181 ctatcttaat gatgtcttca aatccgattt ctttataagg atactgcatc atccagttag
    15241 caagtgccca ttttccttga ctactgattc cttttgtata agcaagtttc aataaatttt
    15301 cttctatttg atacatcata aaaccgcctt tcgtctctct ttctaataag atacgtaaaa
    15361 gcggctgttt tttattgtaa atattttttt acaggtgcaa aacttttacg atggattggc
    15421 gtaattcctt gtcgttcaag tccttctaag tgttcctttg ttccataacc tgcattatgc
    15481 gagaaaccat atccaggata aagcacgtca tattctttca tcaattggtc tcgatatact
    15541 ttagcaatga tacttgcagc agcaatcgac acagatcgtg catccccttt gattattttt
    15601 tcctgctgaa taggcaaatc caaggtcatc gcatcgatca acaaatagct tggtacaatg
    15661 gacaattttt ctactgcttg gatcatcgct aatttacttg cttcataaat attcacatca
    15721 tcgattgtct gctgatcaac gatcccgatc ccgattgcca gggctttttc ttgaacttgt
    15781 tgataaagaa gttctcgctt tttctctgat aattgtttgg agtcattcag ccctaatatg
    15841 atctcatttt tcggcaagat aactgcagct gccacgacag gtccagctaa tggtcctctt
    15901 cctacttcat caatgccggc aatccattgg tgaccttgtg cgtacccttg cttttcaaag
    15961 caaaacattt cttcatattt ttccttaatt aatgcttcct ttttcaatcg tcgttcaaaa
    16021 gaagccagtg cttgctgcac gcctttgcgt ggatcatttc ttaatgattc tagtgtagga
    16081 tcatctattc tctgtatgct tttcaatcgt tctttgatac tttggatgga ttcagtcatc
    16141 acttttttgc tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt ttccttgacg
    16201 aatatcatgc acgactaatt cgctgccacg atcatagtct tctttatacc cacgttttgc
    16261 tgtaatatcc atcagtaatt ccggtgccaa tttttcttct tgctcgattg ataaaccata
    16321 acgatcgctg attcttcctg aataatatcg ggcaaaaaag tctaatccgt aaatcgctaa
    16381 atcatctaaa tggacaagct ggtctttgat cgcgcctgtc agcgctagtt ttttgccgat
    16441 ttcttcatct tcaaatttgg gccataaaat ccctggtgtg tctaacaatt ccaactcatt
    16501 acctaaacga agccactgct gaccttttgt tacgccaggc ttatttcctg tctgtgcaat
    16561 tttcttgcct actagtcgat tcatcaacgt agatttccca acatttggaa tacctaagac
    16621 cattgcccga atagcgcgag gcttgatccc ccgagcagca tctcttgccc gtttttcttt
    16681 caatgcttct ttagccgcag gtactagacc tttaattcct ttactttctt gtgccgtgat
    16741 agctaatgca agatggcctt gtttacgaaa atattcttgc cacagctttg tctgttgtgg
    16801 atctgccaga tccgctttat tcaataaaac aaggcgaggt ttttgctgaa tgatctgatc
    16861 tagcattgga ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa atacgatgtc
    16921 cacatatttc attttttcag aaacttctcg tcgggctttt gccatatgtc ccggaaacca
    16981 ttggatggtc attgttctct ccattccttt cataccggaa tattccccgg ctttacttgt
    17041 ttttttcttt ttcaatataa attcactttt ttattataaa gaaattccat ctattagtta
    17101 agtgaaagtg aaccagtcct cattctatca catcttcact tttttgatga tgcaaatttt
    17161 tattttggtt tctatatatg aatctaaatt tttgacagcg tttcctaaat aagagatgat
    17221 agacgaacaa aacagaaagg agacgaaaca aatgaatagt atggtttttg ttaattttcc
    17281 tgttgctgat gtcaatcgtt ccgttgcttt ttatgaaaag ctgggtttta aaaaaaatga
    17341 agaattttct actgaagaag ctggttcaat ggtatgggat gacacttttt ggataatgct
    17401 tctctctcat gatttttata aaaaatttat aaaagataaa gaaatagctg ataataaaaa
    17461 aacaagtggt gctttgattt cgtttagtgt tgaaaatgcg gatgaagtaa aaaaatttgc
    17521 tcaaattgca aaagaaaatg gtggtacttt ccacgaagta gatatgggaa tgcctgaaga
    17581 agaaatgttt tcattagaag tccaagatct agacggaaat acattagaac ccgtatggat
    17641 gaagatgtaa gcagataact aatctgacgt tttttataac aaaaaaacaa aggcggatga
    17701 tacgataagt attctccgcc tctatttttt ttattcgtac aatctctttt ttacagttta
    17761 taaaagcagt cttctcaccc tttttttaat tgttagatgc cagtgtatgt aaatcaccaa
    17821 tgtgtcatga cacattggtg attttatggt atccttttat tattaactga caaaggagag
    17881 aatattttga acactttgat tgcaaaagac gtttttagat tgcccgaaat gaatgcaaga
    17941 ttgttgtcga cctctgctct tttattagcc cttgatgtca tcttatacaa gatagcgatt
    18001 ggtcctgctt attttcaaat cacattcgga tttttaagta tggcgcttat gggttatcta
    18061 tatggaccga tctgggctgg tttgcttgaa atgttgtcga acactttaaa tttcacgata
    18121 tttggttcag gaacgtttca agctgctttt cttatcacgg ctttccttgg tggatttatt
    18181 aatggcttat ttttatatca taaaaagata aacctgcctt ccgtcatcgc tgcccaatta
    18241 ttgattatga tcccagtcag cctttttatc aattcttggc tgatgtctgt tttgtttggt
    18301 gcagatttca aagtaatttt tctaggtaga ttcatcagga atatgatcca aatccctatt
    18361 caaataatgg ttgtttattc atttatcaaa actttagagg ctagaaaagt gtttaaacga
    18421 gctgtttgat tttacgtact aaggtagtaa actgattttg gattaaacaa taaagcgtgc
    18481 agtctcaaca gactgcacgc tttattgttt ctcactggat ccattttatt tcatcaagtg
    18541 gataatagac aaatcttgct ttacctagaa tatcagtttt attgatcgtg ccaaacgaac
    18601 gactatcttt tgaaactctt cgattatctc caagtacaaa ataattatct tccggaagct
    18661 tggattgtcc cgttagctct tgtagtgtaa agtccgtcgt ataggatgca tttgcatgat
    18721 ctgatttcag gtttttagtt agataaggtt ccttaactac tttcccattg atcttcaatt
    18781 gatcattttg gtagctgaca ttttctcctg gaagaccgat tactcgtttg atataaatcg
    18841 tgccatctgc taattgaaaa acaacaatat caaatcgtct gatctccgaa aatttttcca
    18901 tcacaaccat atcaccttgc ttcaacacgt tttccattga attgccttcc actggtaccg
    18961 ggatgaataa aaatccccgc aacatgaacg caaggaatac agaaacaagt aagtatttga
    19021 atacaagcca gaagcgatta atatagcgtt gtttttttgt caatctctat caatccatcc
    19081 ctcttttttt cattctttct ttattataag aaaaatatca aaaaaatgcg actagatagc
    19141 tgaaataaaa ataattcttt caattaggct attggacaaa aaacttt
//
LOCUS       DADVXB010000048        18771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.049, whole genome shotgun sequence.
ACCESSION   DADVXB010000048 DADVXB010000000
VERSION     DADVXB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.049"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(78..150)
                     /locus_tag="KB902_001285"
     tRNA            complement(78..150)
                     /locus_tag="KB902_001285"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="KB902_001286"
     CDS             531..1100
                     /locus_tag="KB902_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBB6808124.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="KB902_001287"
     CDS             1087..1947
                     /locus_tag="KB902_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6808125.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /locus_tag="KB902_001288"
     CDS             2137..2841
                     /locus_tag="KB902_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808126.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="KB902_001289"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="KB902_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBB6808127.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /locus_tag="KB902_001290"
     CDS             4678..5994
                     /locus_tag="KB902_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808128.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="KB902_001291"
     CDS             5995..6864
                     /locus_tag="KB902_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBB6808129.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="KB902_001292"
     CDS             6919..7728
                     /locus_tag="KB902_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6808130.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="KB902_001293"
     CDS             complement(7831..8460)
                     /locus_tag="KB902_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBB6808131.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="KB902_001294"
     CDS             8630..9922
                     /locus_tag="KB902_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6808132.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="KB902_001295"
     CDS             complement(9998..10660)
                     /locus_tag="KB902_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6808133.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /gene="groES"
                     /locus_tag="KB902_001296"
     CDS             10885..11169
                     /gene="groES"
                     /locus_tag="KB902_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBB6808134.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="KB902_001297"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="KB902_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBB6808135.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(12934..14082)
                     /locus_tag="KB902_001298"
     CDS             complement(12934..14082)
                     /locus_tag="KB902_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6808136.1"
                     /translation="MLKVWVEQTKDGRFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALENYNKSDITFDELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKIIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYEDGKISINGTLDYSSVKMDNAIKTTPKNTYSQREVQLPNRAKELIES
                     VIADNILAGRLTDPDQYIFISTSGTPLTLHSFNAVLHKVEEELELEKSLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(14184..14768)
                     /locus_tag="KB902_001299"
     CDS             complement(14184..14768)
                     /locus_tag="KB902_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6808137.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(14895..15326)
                     /locus_tag="KB902_001300"
     CDS             complement(14895..15326)
                     /locus_tag="KB902_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6808138.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(15344..15664)
                     /locus_tag="KB902_001301"
     CDS             complement(15344..15664)
                     /locus_tag="KB902_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808139.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            15958..16098
                     /locus_tag="KB902_001302"
     CDS             15958..16098
                     /locus_tag="KB902_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808140.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            16396..16653
                     /locus_tag="KB902_001303"
     CDS             16396..16653
                     /locus_tag="KB902_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HBB6808141.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(16624..16932)
                     /locus_tag="KB902_001304"
     CDS             complement(16624..16932)
                     /locus_tag="KB902_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808142.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            17010..17756
                     /locus_tag="KB902_001305"
     CDS             17010..17756
                     /locus_tag="KB902_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBB6808143.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            17771..17974
                     /locus_tag="KB902_001306"
     CDS             17771..17974
                     /locus_tag="KB902_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808144.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            18079..18378
                     /locus_tag="KB902_001307"
     CDS             18079..18378
                     /locus_tag="KB902_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808145.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKGLSPSDVLKEAS"
     gene            18378..18548
                     /locus_tag="KB902_001308"
     CDS             18378..18548
                     /locus_tag="KB902_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808146.1"
                     /translation="MGKFNRALVFSTPFIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPAGRD"
BASE COUNT         6199 a         3221 c         3809 g         5542 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaagt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggcatga
    12841 tgtagtaatt aagaaagaac cctattttaa cagggttctt tcttcttttt ttgttttatt
    12901 ttaagtaaaa ggggcaaaga aggggcaaaa atatcaaagg ctatttagtt tatcaattac
    12961 ttgttgtttg gctcttttgg ttacatggtt atagatagac agagttgtat ttgcatcaga
    13021 atgtcctaca cgttccataa tggctttaag aggtacgccc aattcagata atagtgaaac
    13081 atggctatgt ctaaatatat gcgatgatag acttttttct aactccaatt cttcctctac
    13141 tttatggagt acagcgttaa atgagtgcag cgtaagcgga gtgccacttg tagatataaa
    13201 tatatattga tcgggatctg tgagtctacc cgcaagaatg ttgtcagcta tcacactttc
    13261 aatcaattct tttgcacgat tgggcaattg tacttcgcgt tgcgaataag tattttttgg
    13321 agttgttttt atagcattat ccattttcac agatgagtaa tctaaggtac cgttaatgga
    13381 aattttccca tcctcatagt ccttcatttg taaagctagc aattccccat atctcaaacc
    13441 agtcaaatat aaaaattcag ctattatgcc gtgtagtttt ctgcgaggat tggagtatag
    13501 ctgtttcagt atttgatcaa tttcttcttt ctccagatat tttttatcca tagaaagctt
    13561 tcttttttct tcttccactt ttttagggtg gattttaact gctagagcag ggtttctttg
    13621 gatgtatttt ctatcgattg catagtttag cataacagat agagttgttt ttgtttgttt
    13681 tgtgtagttc agtgagaggt caccaaacgt atacatatct tcaattatct tattaatgag
    13741 tgtctcatct atgtttctaa cgattgtatc atcgcttatg tgcttagaaa catgtttcat
    13801 catcattggc accttcagat agctagtacg tttaacatgc tgcttataat attcatacca
    13861 ttctttatac agctcatcaa aagtgatatc tgatttattg taattttcga gtgcttcttt
    13921 aattttttta tctagaattt tctgagcttt tttccacgct tgtggtgaat tacttgtaag
    13981 tgttgtagat ttttttcgtg ttttttctgt ataaggatct acatatcttt caataaactt
    14041 gaatcgccca tctttggttt gttcaaccca cacttttaac atctcctatc atttgctata
    14101 ataggcataa caaatagacc tatataggtt tgttttctaa aagcacgctc ttactctgga
    14161 cggtggggcg tgttttttat ttattataca gttgctttaa aaatagctgc tttttcaaat
    14221 gatactaaag gagagaagtg gatttctatt tctccctttt ggtttaacgt gaaatgagca
    14281 gttacatcca tttgttttcc tggagcaaca gatcccattg tattttcgtt ggcatatgtc
    14341 tctgattttt tgtcatctgg tccatatact tccacatctg tacctacagg gatatctgaa
    14401 tcgccatcat tttttacggt ataagtaatt tttactactt gtgcaggttg gttttcttca
    14461 aattgatttc tttcatcagt tagttctaca ctatttagtg tatattcagc atcaccaact
    14521 tttacagtgt caccaatctt atagaaggta tcgctttttt cttctttaga agatgaagca
    14581 gaggttgaag atttagttac tttttcgcca ccattatcac ttgctttatt actatctgat
    14641 ccaccattta aagcagaacc aataattata attaaaatta ctgctaatac ccaaaaccat
    14701 acttttttgt aaaaaggttt actaacttta tacatttttc cgtcttgacc cataactttt
    14761 tttgccattt aaatattcct cacttcttgt tataatatat ttgcgatctc agaaatgagg
    14821 tatgagtccg tgtgccagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat
    14881 aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat
    14941 tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata ttccataaat
    15001 ttttcgaggt taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa
    15061 attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta
    15121 tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa
    15181 tgaaaggctt ctgcagtttc gccatataga ttttcattca aaaaaatgat tctaggcttc
    15241 ggataataga agccaggctc tttcatttcc atgtaaacta ctttcaaatt gtattcgctc
    15301 aacatttctt tcaatttcaa atacatacaa cccatcactc caactattca ttttcctcta
    15361 aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct tttccatcaa
    15421 aagaaaaaac agtatcgttt tctgataaat ccacatgttt aggggtttct ttttcttcgc
    15481 gccccagaag atagtctaca gagacatcga aatagtcagc aatttcttgc aaacgttctg
    15541 tagaggggtt tgagttctta agtctatata agacgttttt accatagcct aggtcttctt
    15601 caactttatt taatgatttt ccctgttttt tcgctaactc ttttattctc tcaaacgtta
    15661 tcatatcaat attcctttcg ttcaagaaaa aatatttaac tttatttgtt aaaattcgtt
    15721 gactatttta acaaaaggtg ttaatatcat tcttgtaaac aagtttaaca actaaaaaga
    15781 caacaaaaaa cactattgat taataaatgc caaccgccaa gaaagctttt aaaatcaatg
    15841 tttatatgtc ttatttaact atgttctgat tttaacactg tatgttaatt tagtcaacgc
    15901 agttttttaa aaagttgtta aatttgttta cgaatataaa agaaaggaga gaagaatatg
    15961 gaaaaaacag tctcggcaaa aatcgaagat ttgaaattag acatactgaa acaagcaaaa
    16021 gtggcgatgg aacacgcggt agataaagaa gactctgcca tggttgcagc catagcagag
    16081 attttagctc acgtttagtc atcgttttta cggtcttctg gaagctgacc atagataaca
    16141 gcataatgaa tatctaaata agcttgaaca atttcttttg gcgaaattga ttcgccttta
    16201 gtagatactt gtgattcgtg atttagccat gcaacaacta aatccgcagc gatttcaaac
    16261 ggcgttacac tttgtgtcag ttgccataaa gaatttcaca atatgtatgg tcgtggtaat
    16321 aataccaaag agcaatttga ggaatttatg gaaattaaaa aatacaaaaa atcatttatt
    16381 aaaggaggct aaacaatgaa caaggaaatg agccaaacaa tcaaggtaca aaaaatgata
    16441 gatgatctaa cacatggaat tgatagccaa gccgataaaa tcatcaagga attgcaagga
    16501 caaaaagtta aggatgcaaa aatgcttctc aagactatca actttgaaat gaatccaaca
    16561 aaaagaaagc tcgccgatgt gttggaagaa aagttggctt ccgctatcaa cgagcaagaa
    16621 ttactatttg aaaccgatac ttttaacagc tgatgtttta tagatgacag tttcatccga
    16681 atctatatca tcgccgagag aaaagaatgt tgcttttgac aaaaagccga taagacctac
    16741 aagcggtctt gatgttgcaa gagtagatac cccaatatca ccttgcaagg tattcacgta
    16801 aatttgagaa gaatagaaca ttccatcttt ttcttcgata tttgacgcat catcgtatcc
    16861 aacgaccaaa gtatcggcaa atattttgat tttttctcca tcaagcatag taattacaaa
    16921 ttctggtttc ataaattttc acctccttaa caattatttc agcctgtcac actgataagg
    16981 aaattatacc aaagaaagga atgagaaata tgaatacacc acaaattttt aatttcgagc
    17041 aaaacgaagt tcgaactatt ttagtaaatg atgaaccata ttttgtagga aaagatgtag
    17101 cagacgttct aggatattcg aatccgcaaa aagctattcg agatcatgtg gacttggagg
    17161 ataagacgca gaacgattcg ttcaccgtca atggaacagc agttgttttg attaacgagt
    17221 caggccttta cagtttaatc ttaaaatcaa aacttccctc tgccaaaaaa tttaaacgtt
    17281 gggtaacgag tgaagtcctt ccaacaatta gaaaaacagg tagctattca aacgtacctc
    17341 aaagttttgc acaagcattg cgtttagcag cggatttaga agaaaagaac caattactcg
    17401 aacaacaaat tgccgagtac gaaccaaaga ttagctactt agatacgatt ctttcatcga
    17461 cagatacggt agctacttct caaattgcag ctgattacgg aatgtcggca attgctctaa
    17521 acaaattgct aaacgagtta ggtgttcagc ataaagttag cggacaatgg atactttacc
    17581 gaaaacatat gaaccaagga tacacaaaat cgcacacaag tgagataccg aaagccgatg
    17641 gcggcactaa agttgtaatg aataccaaat ggacacagaa agggcgagtg tttatttaca
    17701 acttattaat cgcagagggc tattaccctc aaatggattt agaggaaatt ggttagaaag
    17761 gagttttagt atgactgaca ttgcagaaat cactcaacga gatagagaaa aaatcaaaga
    17821 atatgtcgaa agttcaaagt tcttaactta caccatgctt gctgaaagat ttggaattag
    17881 caaaagctac ttatctttaa ttttaaacgg taaaaagact tctgcagaag caaacagaat
    17941 tatagattcg attatcacta tgtacgaatt gtagagggag gtaaagtcgt tggaagataa
    18001 aatcattctt acaaaatcag agcttcaaga aatgttaaac atcgagtatg gaacgataat
    18061 ttttaggagg gataataagt gaaaaaacca acactttcag agctgataga agctgctgag
    18121 aaggcagtaa aaccagacga ctggtaccga caaagtttaa tcttggagaa gttccacggc
    18181 atgtcaaaaa ctactttagt tgaatactgc aaggaaatgg aaacaattcc tgaatttgca
    18241 gaaggaatac ttcgtccagg tcactcaacc acatttattc attaccatac ttttatttgg
    18301 tttttaaagt ggaaagacgc aaacaaatat cgtgtaaaag gtttatcgcc ttcagatgtt
    18361 ttgaaggagg caagctaatg ggcaaattca acagagcgct agtattcagc acaccattca
    18421 tcatctacgc tttaggtctt tggggaagca gacaagcatt aatcggcaca atcgtatata
    18481 tggtctggat ttttatgggg cttgatgaag ctgagtacag agcgaaaaag ccagccggga
    18541 gggactgact aatggtcttc ctaagaggag taatcaatat ttttttcctg atttttatat
    18601 tagggttctc cattgatttt tttctttatt ttttgcagaa atccgttaat actttttttc
    18661 tgattatcgg aaaatataaa ggaaaaaata gcaataaatg aaatcaaagt ggtcgctaca
    18721 gaaaattgtg tttcatttaa acaaaataat aaagtgatta ctatggaaaa t
//
LOCUS       DADVXB010000049        18577 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.050, whole genome shotgun sequence.
ACCESSION   DADVXB010000049 DADVXB010000000
VERSION     DADVXB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.050"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            47..3274
                     /gene="fss3"
                     /locus_tag="KB902_001309"
     CDS             47..3274
                     /gene="fss3"
                     /locus_tag="KB902_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6808147.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            3386..3700
                     /locus_tag="KB902_001310"
     CDS             3386..3700
                     /locus_tag="KB902_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6808148.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3713..4087
                     /locus_tag="KB902_001311"
     CDS             3713..4087
                     /locus_tag="KB902_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6808149.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            4088..4441
                     /locus_tag="KB902_001312"
     CDS             4088..4441
                     /locus_tag="KB902_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBB6808150.1"
                     /translation="MKNMEINVEHILDCLDQFGKGELTGEQLTNALTYDEKMFLIMHQ
                     GLLEVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFL
                     KQLVETKQLPVVVND"
     gene            4510..5526
                     /locus_tag="KB902_001313"
     CDS             4510..5526
                     /locus_tag="KB902_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6808151.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            6120..7994
                     /gene="ltrA"
                     /locus_tag="KB902_001314"
     CDS             6120..7994
                     /gene="ltrA"
                     /locus_tag="KB902_001314"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6808152.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            8120..8461
                     /locus_tag="KB902_001315"
     CDS             8120..8461
                     /locus_tag="KB902_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBB6808153.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     DIGGLNVNTEG"
     gene            8521..9663
                     /locus_tag="KB902_001316"
     CDS             8521..9663
                     /locus_tag="KB902_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6808154.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            9688..9942
                     /locus_tag="KB902_001317"
     CDS             9688..9942
                     /locus_tag="KB902_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808155.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            10198..11382
                     /locus_tag="KB902_001318"
     CDS             10198..11382
                     /locus_tag="KB902_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBB6808156.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            11379..11492
                     /locus_tag="KB902_001319"
     CDS             11379..11492
                     /locus_tag="KB902_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBB6808157.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            12262..14172
                     /gene="ltrA"
                     /locus_tag="KB902_001320"
     CDS             12262..14172
                     /gene="ltrA"
                     /locus_tag="KB902_001320"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6808158.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGRSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            14276..14500
                     /locus_tag="KB902_001321"
     CDS             14276..14500
                     /locus_tag="KB902_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808159.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            14513..15016
                     /locus_tag="KB902_001322"
     CDS             14513..15016
                     /locus_tag="KB902_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6808160.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            15143..16180
                     /locus_tag="KB902_001323"
     CDS             15143..16180
                     /locus_tag="KB902_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808161.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            16195..17892
                     /locus_tag="KB902_001324"
     CDS             16195..17892
                     /locus_tag="KB902_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HBB6808162.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKFPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            17885..18346
                     /locus_tag="KB902_001325"
     CDS             17885..18346
                     /locus_tag="KB902_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HBB6808163.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            18359..>18577
                     /locus_tag="KB902_001326"
     CDS             18359..>18577
                     /locus_tag="KB902_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808164.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSI"
BASE COUNT         6420 a         2942 c         4017 g         5198 t
ORIGIN      
        1 gcgagcatct tatttttttg tgcctaattt gaaaggagaa catttcatgt ataaaaaaca
       61 aaaaaagaaa ttatgtgtat taactatttt gagtttggct gttcaatcaa ttgtaggagc
      121 aattgctcct acgattgctt ttgctgatga aattacccat ccacaaacgg taaccgtaga
      181 actagattta gcacatcaat atgctgttga aggaactttt agtgatggtc gtccaatgtc
      241 agaagtcact gttccgcatt atgcagtgta caacggcgtt aaacaagata ttttctgtgt
      301 tgaaccagga gtcccgattt acaatgagtt cactcctgga tatgagaaga acccgttacc
      361 agatatgtcc gataaagcca aattagtttc cgttttatgg aaaaaagtag gtacagatgc
      421 agatactcat attgtggcac agaagatgat ctggcaagaa gttaatgggt atacccttca
      481 ctcaataaaa cgatcagatg gtagtgccgt aaatatcgca gccattgagg caaaaatcaa
      541 tcaagccatt gccgattatc agaagaaacc aagcttccat aatagtacgg ctaaaacagt
      601 attagggcaa tcgactactg tgacggatac gaataatctg aatttgtcag agttcgatga
      661 ggttgtggaa aataccgcaa acattgatta tcgtgtgaat ggcaatcagt tgataatcag
      721 cccaaatgcc aattcaaaag aaagtggtgt gttgacgctt aagaaatctg ctggtaccgg
      781 aacacctgtc gcctataaaa aggctggcca acagacttta atggccgggg cgatcgataa
      841 gccgaacact tatacggtca aaattgatgt ggaaatggag ggttctttga agattaaaaa
      901 agttgataaa gaatcgggtg atattatacc aggaacggtt ttccatttag actttggaaa
      961 aactttaccc gcaaaagacg tgaccaccga taaagaaggc attgcgacct tagatgagat
     1021 tcctcatggt acaaaggtaa ccattactga aaaatcggtg ccggcgcctt atacgattga
     1081 taccacaccc atgactgcca caattaaagc aggtgaaacc atttcagtga cttcaaaaaa
     1141 tacgcgagaa aaaggtcaaa ttattctgga taaaaccgga attgaaacag ggagtgatct
     1201 ttggaacgat aattactctt tagcgggcaa tacgtttgcc attcgcaagg atagcccaac
     1261 tggtgaaatc gtccaagaaa tgaccacgga tgaaaaaggt catgcagaaa caccaaaaga
     1321 gattgccaat gcgttggaat tgggaaccta ctatgtgact gaaaccaagg ctagtcatgg
     1381 ctttgtgaat actttcaaac cagtaaaagt cgaattgaat tatgtcaatc aaacagtggc
     1441 tcttgttacc agtaacgtaa aagggcaaaa ccaagaaatt actggtgaaa ccactttgac
     1501 aaaagaagac aaagataccg gtcatgaaac tcaagggaaa gctgagttta aaagagctga
     1561 atacaccttg tttactgtta aggatggaaa agcggtcaaa tggaccgaga actttaaacc
     1621 agaattgttg aagggaacga aagcttctga tgaaaccgta actttgactt tagatgaaaa
     1681 gaatcaagtt gccgttaaac acttagcgat taatgagtat tactggcaag aaaccaaagc
     1741 gcctgaagga tataccttgg atgaaacaaa gtatcctgta tccatcaaaa aggtggatga
     1801 tagcgaaaaa aatgctgtga ttactcgaga tgttgcggca aaagaacaag tgattcgctt
     1861 tggctttgat ttctttaaat ttgctggatc aactactggc actgccgaaa ctggcttcaa
     1921 tgatctaacc tttaaagtgt cgccattgga aggaaccaat gaaatcaccg gtgccgaaga
     1981 tgaagcgacc acagcttata acgagcaatt agggtttgat ggttatggca agtttgaaaa
     2041 tcttccttat ggggattatt tacttgaaga agtagaagcc ccagaaggtt ttcaaaagat
     2101 tacgccatta gaaatccgtt ctacttttaa agaaaataaa gaggattata ccaagagtga
     2161 ttatatcttt actattaccg aaaaagggca aaagcaaccg attaaaacgg taacggtccc
     2221 ttatgggaat ctaaccaatg agaatttctc agtcagtttg aaccgtttga tgctttatga
     2281 tttgcctgag gaagaagata gcttaacttc tcttgcgact tggaaagaag gagataaaga
     2341 attgactact cttgattcta ccgagctagt cgataaattg agctataatc tacatgaaat
     2401 caaagaagac tggtatatcg tagctcaagc catcgatgta gatgctacaa aagctgccca
     2461 agaaaaagat aaaaaagcca aaccggtggc gattgcggaa acaaccgcaa ctttagcgaa
     2521 taaagagaaa acaggaactt gggagattct gcataaatta actgtcgaac aagttttaga
     2581 caagaccatt gtcttattca actatgtgta tgaaagcaaa gaagcctatg aagctggtga
     2641 tgagccggta gcgaaggatg ctagcttgaa caatcaagcg caaactgtta attgtatggt
     2701 ggaacgtcat gtttccatcc aaaccaaagc gcacttagaa gaaggttctc agacctttac
     2761 tcatggtgac gtggtagata tgtttgatga tgtatccatt acccatgatg tactagatgg
     2821 ctcaaaagaa gcttttgaaa caattctgta cgctttattt ccagatggta caagtaaaga
     2881 aatttggaaa tctggcaaga ttgattacga agtgaatgac aaagaattta ccaaaaccgt
     2941 acttgcggaa aaagtggata caagtaaata tccagaaggt acaagtttta ccttcaaaga
     3001 aattaactat gacaaagatg ggaatatcaa tggaaaacac aatgaagatt tgaaagaaaa
     3061 atctcaaact ttaacgccca aaaaagttcc gacaacacca agtacaccag aacaatctga
     3121 aatgccaact gttccaagtg gctctcaaga atctagtcct acagtgaagg cattccctca
     3181 aaccggggag aaaacttcca atgtgctact gttcattggc tttagcttga tctttgcgac
     3241 ggctggctat tatttttgga atcgtcggaa ctaaggtgat aagatgaaac atgtaaatag
     3301 tagaaaacaa tacgcgcgac cgcctcctaa aaaagtggtc gcgctatttt tgtattcaaa
     3361 actaacaatg aaaagaggaa aaaatatgga attgaaattt gttgtaccag atatggtcga
     3421 gacgttcgga aaactaacat acggtggtga aggtgaagtt ctatcggaag ggtatggtcg
     3481 aaatactaca attgttggtc gaagttacca tctgttttca aataaacaac gggccgatga
     3541 tattgaagtg gtggtagctg cggaagccgg cgaaaaggat tttgaccaag atcaaccact
     3601 aaaagctgta aatccccact taattgccaa aggctatgaa attgagaatc gtgggtttac
     3661 cgattacgtg ttgtatgttg atgatttagt gaaagcatag gaggaaaaga agatgagatt
     3721 aacagaaggt attgtcgtag attcaggatt aacctttggc aagttgcgtt tttccgcatt
     3781 acgtcgagaa gtacgcaagc aaaatgagga cggaacggtt agtaacgagg taaaagaacg
     3841 gacctataat ttgaaatcct ccgcgcaagg tcgaatgatc caagtcagta ttccagcaaa
     3901 tgtaccctta cgcgagtttg cttatgatgc agaggtagag ctggtcaatc caatcgtgga
     3961 tacggtcgcc aattatgttt ttcgggaagg aaccaccgtt aattggttta tcaaggcaga
     4021 tgatttagtc ttgaaacgac aactgaatca aggaaaacct acgaaccaaa atgaaggaaa
     4081 gaaataggtg aagaatatgg aaattaatgt tgaacatatt ttagattgtc tcgatcaatt
     4141 tggcaaaggt gagctaacgg gggaacaact cactaacgca ttaacctatg atgaaaaaat
     4201 gtttctgatt atgcatcaag ggttactgga agtaggtaac gatgccaaag aagactttga
     4261 tgtactggat tggttagggg aagaagagtc tttctttatg gttgtcgagg taaatgaaag
     4321 tttatgtcgg caggcagaat ctgttttgga agaaatcgat gtggagatgc cggatgccat
     4381 cgaaagattt ttaaaacaat tagtggaaac gaaacaactt cccgtagtag taaatgacta
     4441 gcataacttt ttgaaattgc ccaatgaaat cctattgggc tttttcgact ggaggtggaa
     4501 accatcaaaa tgtacaaagg acatcgcata cgcgcaggag atcaacactt gatttatcac
     4561 tttgttcttg gctggctaat ctttttgttc attggttgga tgagcgtctt ttatttacaa
     4621 gaacttagac aatttgatat ttctaaggta tcattttcca ctagtgaaat tggctggtct
     4681 atgaaggatg taatctgctt gctaggaagt ctcgctcttt caggaagcat gatgttactt
     4741 tatatacact tttttcagga tcattggcga agtctttggc atcgacaaaa gttagctcgg
     4801 atgattctag aaaaccattg gtatgaagta aagcagactc aaggtgaagg ttttttcaaa
     4861 gatttgaata gtagttggac caaagagagt atcagttact tccccaaaat ttattatcga
     4921 atgaaagatg gcttactttc tattcgcgtt caaatttcac tgggaaaata tcaggatcag
     4981 ctattgaagt tggaaaataa gttagaaagc ggactgtatt gtgagttagt agaaaaagaa
     5041 ctcaaagact cctatgtgga atacaccttg ttatacgata tgattgccaa tcgaattggg
     5101 atagaagaaa tagtggcaga aaatggggcg ttgcgattga tgaaaaatca agtatgggcg
     5161 tatgattcct tgccgcatat gttaattgct ggcggcacag gtggtgggaa gacctatttc
     5221 ttactcacca ttattcaagc actattgaag tcagatgcag aattgtttat cctcgatccc
     5281 aaaaatgcgg acctcgccga tttaggtacg ataatgcctc acgtatactc ccaaaaagaa
     5341 gaaatttctg aatgtgtgga agatttttac gaacgcatga tagctcgtag taggtcaatg
     5401 aaagaaatgc ccaactacaa aacaggagag aattatgcgt atctcggact tccgcccaac
     5461 tttttaatct ttgatgaata cgtggcttat atgggtgcga atcgttttcc tacaagcatc
     5521 gaatagatgt gaaatggaag cctattgaga ttatcaatag tgacaactaa tgttttgaga
     5581 gatggaatga aagccttcaa gttgagctga aacatccccg ctaatactcc tacatgctct
     5641 aatcaatgaa gtagattggt tttggtatga agctaggtga agtcgtctga aatctgccta
     5701 agtgcttgag cataaggctg actatagggc gggcggctga aaaagataac tatggtaaga
     5761 atgtctgaaa atgactgacg aatctgcgaa tgtacgggtc taaaaggctg atcttattga
     5821 aagataggaa catacggacg tatggtgaga taccgacaag taaggttcca tgatatgaaa
     5881 atcgggatag ctaacgaaga agctataatt tcacaggctc atagtagata cctaaggtta
     5941 tacatgatag ctaaaaacat tggaacgatg taagcagaaa actatcaatt aaatgactac
     6001 ttctagatag gtgcatataa gtaataacga aattgctttg tttctgtgaa agtaagggca
     6061 cagtaccgat gaagcgtcta acaaatgtgg agggatagcc ctaagtctat ttaataacaa
     6121 tgaatgttga aacagatgaa gttcaaggat ctggtaagaa cgtgggaaaa tccgttatgg
     6181 aggtgccacg cttgaacaca aaaatacgtt actgggaata ttatgatcta caagaaacat
     6241 tcgatcagct atttactcaa agtagaaacg ggaaaaagtt ttatcaatta tatgagttaa
     6301 tcatttctga aaataatatt cttttagcat accgtactat caaggcaaac aaggggtctt
     6361 cgacaccagg aacggattcc ttcacaattg ataactataa ggaaatgaac caagcagagt
     6421 ttatccatct tattctcagt catttagaaa attacaaacc aaaatccata aagcgagtaa
     6481 tgatacctaa acccaatggt gagaaacgcc cattaggaat tccatgcatg attgatcgaa
     6541 tgatccaaca gatgttcaag cagatactgg agccaatatg tgaagctaag ttttatgaac
     6601 atagctacgg tttcagacca ttgagaagtg caaagcatgc tctaggtcgc attatgtatc
     6661 tcataaacat cagtaaaatg cactatgcag tagacattga tatcaaaggt ttctttgata
     6721 atgtaaacca ccgtttactg ataaaacaat tatggaatat aggaatttgt gacaaacaag
     6781 tcttagctat tctttcaaaa tctctgaaat cacccattca aggagaaggt atcccgagca
     6841 aaggaacgat ccaaggaggt atcatttctc cactattatc taatgttgtt ctaaacgact
     6901 tagaccattg ggtctcaaag cagtggcata cctttgaaac aaagtatccc tatactaaag
     6961 gttacaataa atttcgtgct ctaagagata caaatctaaa gcaaggctat attgtcaggt
     7021 acgcagatga ctttaaaatc atgactaatg attatccgac agcattaaaa tggttccacg
     7081 ctgtcaagct ttacctaaaa gacagactta aattagatat ttccaatgag aagtctaaaa
     7141 tcgtcaattt gcgtaaatgt aagtcggaat ttttaggatt cgctatttgc gtgaaacaaa
     7201 aagggaaaaa atgggtttgt aattcacgta tttctaacaa aaaaaaggat cagattaaag
     7261 aagagattaa acaaagaatc aaagatattc aaaagagtcc tacagcacaa aatgctctcc
     7321 tgtttaatgc tctcgtgctc ggtgttcata attatttcag gtatgccact catattaatt
     7381 tagatttgaa taggatgaac tacgttcttt cattcactac ttacaaccga ttatcaaatt
     7441 gtagtacaag atgttacccc aacaaagctt ccccaactta caaaaagttt tactcaacaa
     7501 cgatgaaaac gtataaagta gctggagtct atttgtaccc tctttgcgac gtatctacaa
     7561 aaacaattta cggatttaat acggaggata caccgtttac tccgtttggt cgtcaaagat
     7621 tggagcacaa aagcctacag tctcttgtgt tccaagaatt aagaaaattg atggaatcga
     7681 aaataccgaa tagaacggtt gagtatttag atagtagaat atctcgttac tcaatgaaat
     7741 caggcaagtg tgagattaca aaacaatttt tgccagcaaa agccgttcac tgtcatcact
     7801 atttgccaaa aagtcttggt ggagacgaca aattcgataa cttgagaatt attcataagg
     7861 atatccatct tctgatccat acaacaaata aaatgataat cgatcactac gtgcatgaac
     7921 tgaaactggt gccagagcaa atagcaaaaa tcaaccttta tcgaaagatg tgtaatctgc
     7981 aaaacattca atagaaaata aatagatgga acgccgtatg aggtgaaagt ctcacgtacg
     8041 gtgtggagcg ggggaaaaga tggagattat atcaaattct tacctatcgc tatagatgtt
     8101 aacgacaaaa gaaagtgcgg tgattttgaa taagctcaaa caaatcgtga tgttaggtcg
     8161 tcaatctggt ttctttctga ttctagcttg tcaaagaccg gatgcgaaat atttaggaga
     8221 cgggattcgc gatcaattta atttccgggt ggctttgggt cgtatgagtg aactgggata
     8281 ttccatgatg tttggcgagg ttgataaaaa attctttatg aagcgtatca aaggtcgagg
     8341 ctatgtagat acgggaggga gtgtgattag tgagttttat acgccacttg taccaaaagg
     8401 atatgatttc ttaagggaaa ttagcgacat tggtggatta aacgttaata cggaaggata
     8461 aaataatagt atgtagccta ggagtgtcaa gaatcctggg ctttttttac gaggtgattt
     8521 atgacatttt tagatttatt cgctgggatt ggtggctttt gcttaggtat ggaacaagcg
     8581 ggtcaccagt gtatcggctt ttgtgaaatt gatgattttg ctcgccagag ttataaggca
     8641 atccatgata caagtaagga ggtggaaatg catgacatca caagtgtatc agacgagttt
     8701 attcaatctc tcggaccagt ggatatcctt tgcggtggat ttccgtgcca agctttttca
     8761 attgcgggaa agcggcaagg attttccgat actcgaggta ctttattctt tgaaatcgct
     8821 cggttcgccg ctattctcca acctaagttt ttattccttg agaacgtccg gggattactc
     8881 aatcacgaag gaggggctac gttcgagacg atcctccgaa cgctggatgg attggggtat
     8941 gatgtggaat ggcaagtgct taactcaaag gcctacgttc cccaaaaccg tgagcggatc
     9001 ttccttatcg gacattctcg agacgcatgt accgaacaag tatttcctat cattggatcg
     9061 tctccaacat ctgatcaaaa catcagaaac ttattaaata tcaacccttc caatcgagga
     9121 atggggggac aagtctatgg gtcagatgac gtagcgccta ccttgaccgg tgatgaagga
     9181 atcaaaatcg cattgccggt agatgatgga atttctgtag cgggtatgtt actgggaaat
     9241 tttgaacaag gcaatcgggt ttatgagata actggaacag cgcctacttt gtcaacgaaa
     9301 caaggcggaa cgaagatcat gcttcggaaa aacgaaacag aatatcaaga ggtgaagcca
     9361 gggaacagtg tgaacctggc ttttcctaat tccacaagtc gtcgaggccg tctgggaaaa
     9421 caaagtgtgc ataccttatt aacaggagac caacaagcag tcgtcacgga tcagtatcaa
     9481 attcgaaagt taacacctag ggagtgctgg cggcttcagg gctttccgga ctgggctttt
     9541 gatcgagctt ctcaagtcaa ttcagatagt cagttgtata agcaggctgg aaattctgta
     9601 acagttccgg tcatttttga tattgctaga agattaaagg aggtaaaaac agatgattta
     9661 tgatgagttg attggggaat ctactgggtg attggcaaga ttcagtcaga tccggaattg
     9721 gaagaagaac tgtaccggct caattttgat attcgcaaaa acggggtgaa agtccctgat
     9781 gatccgtatg taattgatga ggaaacggat gctcgaatgg agctgaatca agtcatcagt
     9841 gaattggaac gaattgcgga ctttgctaaa gaacctgata tccgccaata cttgtttgag
     9901 ataaaagcag agttggaaat tgagggtatt accgcggagt aacggccaaa taaaccactg
     9961 ataggcactg accgcggggg atttgcgaag cagaaatcct ccgtggtgct gtgcctgttt
    10021 atggacggcg ttagccggcc atgatgtctc accccccgta tctaacaggg gggtacaaaa
    10081 acacaaaaaa taagcaagca acgataagga atggctgtcc tatcaaggat aataagcaat
    10141 ttgtgtagat gttaactgat ttgaaaaagt taacacctta aatttggagg tgagaacttg
    10201 gcacaaagga atttagatta tcggctatta aaagaccggc gtaatgaata tggcgtttca
    10261 caaaataaat tagctacgac ttgtggactt agtcgcccgt acttaaatca gatagaaaat
    10321 ggtggcgtaa ccgcctctac aaagaccatg agaaaaattt ttgatcaact ggaaagtttc
    10381 aatcccgatt tacctttaac gttactattt gactatgtaa ggattcgctt tcccacaacg
    10441 gatgtgcgga aaattattca agaaattctc catttgaaat tcgagtatat gcttcatgaa
    10501 gattacgcct tttactccta tcaagaacaa tatgtcatgg gcgatattgt agtgatgtta
    10561 tctcatgaag aagataaagg tgtccttttg gaattaaaag gtcgtggttg ccggcagttt
    10621 gaaacttttt tactcgccca aaagcgtagc tggtacgact tttttgaaga ttgtctaaaa
    10681 gccggtggcg tgatgaaacg cttggattta gcaatcaatg atcgagtggg gctactggat
    10741 attcctgatt taacgaaaaa atgtcagaag gaagaatgta tctccttgtt tcgtaccttc
    10801 aaaagttacc gttccgggga actgttgaaa gctgatgaaa aggatggtat gggcaatacc
    10861 ttatatattg gcagcctcaa aagcgaggtt tatttttgtt tgtacgaaaa agattatgaa
    10921 caatatatca agttagggat tccattggac cagaccgaaa cgaaaaatcg ttttgagatt
    10981 cggttgaaaa atgaccgtgc ttattatgcg attcaagatt tgttaaaagg tcgtagcatt
    11041 gaaagtacca cgttttccat tatcaatcgg tatttgcgat ttgcggataa agtagatgga
    11101 aaacggcgaa ccaattggcc cttgaatgaa caatggggtc gttttattgg acggaatcgg
    11161 aaagagattc aattaacttc tgaaccgaaa ccgtatacca ttgaacgaac attaaattgg
    11221 ctaggtagac aagtcgcccc tacgtggaaa atggctaagg agttggatcg attgaatcaa
    11281 acaacgtata tccaggatat ggtacagaat gcgcgactct cggaccggca taaaaagatt
    11341 ttggagcaac aaagtatggc aatcgaaaac ttgattgtat gaaaagagga attttgatgg
    11401 aaattgtaaa agatatgtta ttggtacttg gtggcagtat gcttggtgtt accgtgatgt
    11461 gcttgatgaa tgcaagtgca gcagcggatt gagcaatgga aaagaaagga aagtgacaaa
    11521 atgaatttcg gacaaaattt atgtgcgact cgttccttag tgaaaagcta aggcactaat
    11581 aaaagaacga aaaagtttgg ttattaggag aactgataat ctgacaggtg gaatgatgaa
    11641 gtaacgctct gaaacgcctg ccctgagcct ccgacaagca ttgtatgagg aaactcagaa
    11701 tgtttgaagc tcggtaaaga cggctgaaag ataccgtaat agttgatgaa catatatctt
    11761 ctatcgaaaa ctatccagag gtgggtagcg tatccaacag gtcgggggtc tataaaatat
    11821 ctatggttag aatgttctat aaggaactga cgaaacagcg aatgtacggg tctaaatttg
    11881 aactttgtag aaatgcaaag gtacgagaaa tcgtagctgg tgtggcaaag taagaatata
    11941 ggttatgaaa tgccatataa cgttacaggc ggtatcaagc cagcaggctt atagctagtg
    12001 acctaaggat atatatgtat agataagatt atcggaacga ggaaaggtat tgggttctca
    12061 tcaagagaat aaactgacga agaacaataa gcagttgaac taatgctgaa aagcagaggg
    12121 cgaacctaag aaattcttgt aatgagaatg gaggaatgcc ctcaagtcgt gtatatatta
    12181 gaaaagtatt atgttgtttc aataaggatt acgagtaaga taaaaaagct cactcaattt
    12241 caagtaaagg agtgaagcct tatgcctaaa aataaaaatg aaacattgtg tgtagaagat
    12301 ttaagacacg ctgaatatta cgaaatgcaa aacacctttg atgatttata tgccaaaagt
    12361 aagaatggag atattttcac tcatcttatg gatattatcc tatcgagaga aaatatatta
    12421 ctggcatatc gaaatatcaa agcaaatgca ggcagtaaaa cagcaggaac agacggtaca
    12481 ataattaaag atattggcaa attgccagca gaaacagttg tcaaaaaagt aagatacatt
    12541 gttgcaggca gtccacatgg gtatcgacct aagccagtga ggcgaaaaga aataccaaaa
    12601 ccaaatggta aaaccagacc tctaggtatt ccttgtatgt gggacaggct tatacaacaa
    12661 tgtataaaac aagtattaga accaatctgc gaagctaaat ttagtgaaaa cagctatggt
    12721 tttagaccta ataggtcagt tgaaaatgca ataaaagcaa cctataaccg cctacaaatc
    12781 agccagctac attatgtgat tgaatttgat attaagggtt tctttgacaa cgtgaaccat
    12841 tccaagctga taaaacagat atgggctatg ggaatacggg acaagcactt gatattcatt
    12901 ttaaaaagga tattaaaagc tccaatcaaa atgactaacg gtacaataac atatccagag
    12961 aaaggaactc cgcaaggggg aataatatcc ccactactag caaacattgt tcttaatgag
    13021 ttagaccatt gggtagaaag ccaatggcag gaaaatcctg ttacaaaaaa ctatgtggtt
    13081 catatcaata aaagcggtag cccatgtaaa agcaacgctt acaaagaaat gaagaaaaca
    13141 aagttaaagg aaatgtatat ggttcgttat gcagatgatt ttagagtttt ctgccgctac
    13201 aaggaaagtg ctgaaaaagc caaaatagca atcactcaat ggattgaaca acgattaaaa
    13261 ttggaagtat cacaagaaaa aacaagaatt gtaaatgtta gaaaaagata ctccgacttt
    13321 cttggtttca agattaaaat gataccgaga agaaagaagt tagttgttaa atcacatata
    13381 agtgataaac aattcaaaaa ccaaaaagac aagctggtat cacaggcaaa gaaaattgct
    13441 tctccctcaa aagggaaaac ggaattagaa gaaacaagac tttataattc aatggtatta
    13501 ggtatgcaaa attattatca gattgcaacg aatgtaaatc tggattgtat gaaactgaat
    13561 agagctgtaa tggctatctt cactaacaga ttaggtacaa acaaaagggg cagattgaga
    13621 aaaacaggca gacaacttac gacaaaggag gcaacaagat atggtagatc taaaatgctt
    13681 cggtatgttg ctggcgaggg cgaacctatt ttccctgttg gatatatcca acacagaaaa
    13741 ccaatggcaa aggtgtattt agcgaattgc tacactctag agggaagaaa atttatccac
    13801 accaatctaa gtgttgataa attactgatg taccagttaa tgaaattatc tttggaaaat
    13861 cgcacaatag aatacgcaga caatcgaatt tcgctatttt ctgctcaaca tggaaaatgt
    13921 gctataactc tggaagaatt tcaacaagct aatgaaatac attgtcatca tattgtacca
    13981 actggagctg gtggaaatga cgattataaa aatcttattt tggtaaaaga ggcggtacac
    14041 cgtctaatac acgctaaaac agaagaaaca atacaaaaat atatagctct attgaagcta
    14101 aataaagtcc agctcataag actaaataaa tatagagtat tagctggcaa tcaagaatta
    14161 aacttgatat aggtctacta cataaatact tttcaatata aacacgatgg aacgcggagt
    14221 gcggtgaaag tcgcacgctc cgtgtgaatg gggggaaaag tttgagatat ttataatatc
    14281 aggaacttac ctatccatat atcaatggtt tttaaccaat gctcaatctt tagtcttact
    14341 agcgattgtg gtcattggtt tgtttttagg atttaaacgg gagttttcca aactgattgg
    14401 cttcttggtg attgctttga ttgcggtagg tctggtcttt aatgcttctg gtgtgaagga
    14461 tgtcctactc aatttgttta accgaattgt cggtgcctga gggggaatca caatggaaca
    14521 gatgcgtgtt tatattgcga accttggaaa atacaatgaa ggtgagttgg tgggggcatg
    14581 gtttacccca cctgtcgatt ttgatgaagt gaaagaacag attggattaa atgacgaata
    14641 tgaagagtac gcgattcatg attatgaact gccttttgag attgatgagt atacgccaat
    14701 tgaagagatt aatcggttgt gtaacttagc ggaggaacta gaaggaacgc caattggtga
    14761 agctgcttct gagattcaac acgctttctt caattctttc gaggaaatgg tagagcatgt
    14821 ggatgatatt gtctattatc cagattgcga tgatatgagt gatgtggcgc attacttgat
    14881 tgtagaagct ggtgattttg gcgaagttcc agaacaattg aagccgtata ttgattttga
    14941 tgcttgcggt cgagatttgg agattggagg aaattatttg gttactagtc gtggagtttt
    15001 tgagtatcca gaatgaatca aacactatat atagtgtttg attagtatat gtaagcaaaa
    15061 aaacacaata tatagagtgc aaactgaagg gtaatgtgat ataatatttg ccgaagaaat
    15121 atttttgaaa tgaggtaata ttatggcaaa tattcaaaca agttttattg atttccataa
    15181 ttcaattaga ttggacgtag aagacaatac gctacttaag gactataaag accaagtaat
    15241 tgatggatta aaagattact tacctgatga tgtgaagttt gaaacttttt tacagggaag
    15301 ctattctgtt tataccggaa taaaaagctg tgatgaaaaa attgattttg acatcgatat
    15361 tgcagttgct ttcgaaattg atcatactgt ttatgaagat ccaagggagc ctaaactgtg
    15421 ggtaaaagag gcgctagttg aaatttttcc taatgctcaa gttaatttaa aagtaccttg
    15481 tgtaactgct acatttactg gaaaaaagac aaaaaaaaat gtgcacgttg atgttgcggt
    15541 ttatgctaaa gaagatgaaa attatttctt agcaaaagca aaagaattca gtgctcccga
    15601 aaaccgatgc tgggaggaag cggatcccaa agtattaaaa gagaaaatta atagtcatgt
    15661 agcagattca gatgatcgaa aacaatttcg aagatgtatt cgctatttaa aaagatggaa
    15721 agataacaat tttaaccaag aatataaacc aacaggaatt ggacttacaa ttaatgtgat
    15781 ggatacgttc ctagttaata agtccactga ttttttaact agaaaagttc agtataatga
    15841 tatggaatgt atgaagcaga ttgtttcttc gctgaaagat tcatttgtgt atgagtacag
    15901 tgaaacagat ggttggcatt atcgtctaca tgcatatctt ccagtgaagc ctaacagtga
    15961 cacctattca aaaatgacag tgaatcagat gagtgatttt aaaaacaaac tttctaaatt
    16021 atatgatgat ttgattttcg ctatcgatac tgaagatgag tatgaagcta caaaacgatt
    16081 aaataatcaa tttggggagg attttttaat tatttcagaa gaagaagtta cagaaaaaaa
    16141 cttaagaaat gcatttgtta cagactatcc gagtgcttag gttggtgtta aagattggat
    16201 tatactgata ttttaaaaga aaagctaaca gatgttgtgc gtttattcga tggtaattac
    16261 tatggggatt tttcatttgc tacaattgga aagttgcgtt taaaaattga aataccaaaa
    16321 cattttccat tggtacttcc taggatttac attcataatt ttgatcattt aggactttac
    16381 ctaccacatg tagaaaaaga tgggttggta tgtttttctt cagatataaa ttatttagta
    16441 gatgaagaaa attcagaatt ggttttattg cagtgtgtta ataaaactat aaaaacaatt
    16501 gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa aagagtttgt tgctttttgg
    16561 gacaaacaag agaatcaaat ttcgttattc tacctttgtg aaccagcgtt gtttatcaag
    16621 tcagttgata caataatgta cggtaagtct ttggttgctt tggataaaga gaacgaatta
    16681 caattaaatg cagcgagtag attgtttaat ggagagaaag aagatactca tgaattagat
    16741 gcatactatg ttccaattag aaacaagaat aatattatgc ccccgaagaa taataaagca
    16801 tggtcaaaga aggatatttt acaaatagta aaaaaaaatg taacaggtgc aaataaaaga
    16861 ttttttttaa aacttgaaaa aagaaagaat agacataatg ttttacttat tctagatatc
    16921 ccaattgaag aaaagtcaaa taatgtcata attggatttc tttttacaaa acaatctgga
    16981 tctataaaag attataaggg tacgcctagg actgtattag ttcagcgtca tgatgaatta
    17041 tatttggtga atagaacgag cggagaaaac tatggattgg gtgctaatat agctattgtt
    17101 ggggtagggt cagttggcag taaaattgct gaaaatcttg gtccattagg tgtgagaaag
    17161 atgacactca tagacaatga ttgttttcaa gctgaaaatt tgtatcgaaa ttcacttggt
    17221 gcagatagtt taaaaaatgc ccgatctcag aataattttt ttaaagttga tttaatgcag
    17281 gaggagctcg aaaaaaaatt cccatacctt tgtgttgaag tggagtcaat gaacgtttta
    17341 gacttaatta gtatgcaacc tggttttttc aaggaatatg actatgtttt tgtttgcata
    17401 ggagatacaa tggcaagcct ggctttaaat aattattttt ccaaaagtag tcaaaaagtt
    17461 ttctattctt ggctggagcc atatggcatt gggggacaca ctctatttat aaattattct
    17521 ctaaatcaaa aaggttgttt caattgtctt tatacagatt caaactctaa aaataggtgt
    17581 tcaaatagag cttctctggt aaaagaagga caaatttttg aaaggacttt agcgagttgc
    17641 cgctcaaaat ttataccata taatgctatt gcctcgacgg aatgtgcaat taatgcaata
    17701 aaacttttcc ataaagtcaa tcaaaataat atgaccaata gtactctttt ttcatggata
    17761 ggagatggga gtacttttga gaatttagga tatcaatata gcgacagaaa tacttttctt
    17821 aatggagtca ataagtttga agaaagattc ttttctaaat attgcaaagt atgtggggag
    17881 ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa gtaagggatg aagttcttaa
    17941 gatatttgaa caatatcggc agggaaagga tgacttgcct gaagctggag gagttcttca
    18001 tggaaaaaga cttaagaatg ggagcataat aattaccgat ataacaacac ctcaaatagg
    18061 agatatacaa aaaagattac tctttaaaaa aaaccgagaa attcatcaac agctttctaa
    18121 tgagaaatgg atagaatcaa ataagttttc tattgcattg ggagaatggc atactcatcc
    18181 tgaagctgta ccaactccat caaatgttga taagaaaagc tggagactga acgtgagcaa
    18241 gcaacatgat gatagagttt atgtttttat tatcgttgga ttttctgatt tgagaatgtg
    18301 gttactgtca aaaaaatcag atattaggca ggctataaaa ctataaagga gtgattaggt
    18361 gaaatcacaa aagaatattt ggtggtgggg gtttttagta ggaaaggtaa tgataccagc
    18421 ccttctctta atttctctac cgatgattac ttttttcttt accaataaaa aaatgagtaa
    18481 agaagccgtg atttttttct ttggagacca aaaagctacc tttattgaaa cgttagtaac
    18541 atctcttcag cttaatttga attacatttt ttcaatt
//
LOCUS       DADVXB010000050        18546 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.051, whole genome shotgun sequence.
ACCESSION   DADVXB010000050 DADVXB010000000
VERSION     DADVXB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.051"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(1..774)
                     /locus_tag="KB902_001327"
                     /pseudo
     CDS             complement(1..774)
                     /locus_tag="KB902_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002399485.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(798..1412)
                     /locus_tag="KB902_001328"
     CDS             complement(798..1412)
                     /locus_tag="KB902_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002399484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6808165.1"
                     /translation="MAKIGYARVSSTDQNLDRQLELLSDCDKIFTDKLSGKDTNREAF
                     QEMMNFIREDDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEDERKYILETQKQGIALAKAKGKYKGGKPKYRENDPRLQLAF
                     NLFLAGSTDKEVEEQTGINRRTFRRYRMKYGITDEVRQKQKDVK"
     gene            complement(1565..2155)
                     /locus_tag="KB902_001329"
     CDS             complement(1565..2155)
                     /locus_tag="KB902_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6808166.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSKRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSLQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLTEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLTKMEEKKEKGKANAH"
     gene            complement(2726..3778)
                     /locus_tag="KB902_001330"
     CDS             complement(2726..3778)
                     /locus_tag="KB902_001330"
                     /inference="COORDINATES: protein motif:HMM:TIGR00341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HBB6808167.1"
                     /translation="MSENVYYSAKEFYAKINQDLTIRREDMVILVCSIVIACIGLNMD
                     TTPVVIGAMLVSPLMTPIQGVGMGLSLFDQQMLKKALKILLVQIMVSIVTASIYFFIS
                     PISYASNEILARTQPTIWDVIIAFFGGIAGVIGSRKKAMNNIVAGVAIAAALMPPLCT
                     VGYAIALKKMPYFLGAGYLFLINCFFIIIATFIGVQVMRIPKSVKVDSEEKSKMNVVI
                     VILSIVILIPSIISASQLVGKSIIENGLRRMLSEELGNNVIVINKSIDQENKIIYLTT
                     SGEKISDTRIKKIEESLPMYNLKGMSLEISQITNTQQLSGEDLVRLLKEYEESKKSNS
                     IEKTKRVNSTEDSNNE"
     gene            4007..4606
                     /locus_tag="KB902_001331"
     CDS             4007..4606
                     /locus_tag="KB902_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6808168.1"
                     /translation="MRVAYIRVSSIDQNEQRQVEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKEYNVTRQTVYRIKKEI"
     gene            4624..5685
                     /locus_tag="KB902_001332"
     CDS             4624..5685
                     /locus_tag="KB902_001332"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808169.1"
                     /translation="MSIEEYWNRLGKPKTIYDPQQIEKFLNVFIKKTNGNLNLDTIHN
                     YDFSDSIVKIERNESLFKIYWKDYEQVINKHLSHSATEDEIDEVMIYGGFTFIYYLMD
                     IHKISIDNLHGNVYVIIHCNYFPEKAAIKHLKKDFKFVNDPYTVSEDNATRKKIYFSD
                     SNNYNHECVIDVLPISNSIIFQKIKPWNTSFSHKLLTRAALNEIINPVYKNKQLFSSL
                     NNDNEDKIRSMINDLRYSLERLIKFYFITESIKNEWNGLDLESSDSIIVDILQKFGYS
                     TLIKFKKPLKLKGINLNQSFINELNKYSHYSGYFPTKSILLQCHKNYCEILEELFDLA
                     EYGINIEALTICKEGVSKT"
     gene            complement(5870..6301)
                     /locus_tag="KB902_001333"
     CDS             complement(5870..6301)
                     /locus_tag="KB902_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBB6808170.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
     gene            complement(6335..6520)
                     /locus_tag="KB902_001334"
     CDS             complement(6335..6520)
                     /locus_tag="KB902_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBB6808171.1"
                     /translation="MPLTGKEMLKLLKKNGWVERRQEGSHHHLYKDGVRITVPVHANQ
                     DLGRGLERKILKDAGLK"
     gene            complement(6613..6792)
                     /locus_tag="KB902_001335"
     CDS             complement(6613..6792)
                     /locus_tag="KB902_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808172.1"
                     /translation="MPIANGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFEVPALRK"
     gene            complement(7173..7880)
                     /locus_tag="KB902_001336"
     CDS             complement(7173..7880)
                     /locus_tag="KB902_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808173.1"
                     /translation="MNKVVYQLTMEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSHNYLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSLSEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(7873..8310)
                     /locus_tag="KB902_001337"
     CDS             complement(7873..8310)
                     /locus_tag="KB902_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808174.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNNKWFFQALLCLEAGVKPSTIKPSEYQALE
                     LTYAKFVETKKAKTVSSEWSDYFENVNKYGACYIMKKEDNENE"
     gene            complement(8325..8576)
                     /locus_tag="KB902_001338"
     CDS             complement(8325..8576)
                     /locus_tag="KB902_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808175.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETSLV
                     EDAPNMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            complement(8576..8782)
                     /locus_tag="KB902_001339"
     CDS             complement(8576..8782)
                     /locus_tag="KB902_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBB6808176.1"
                     /translation="MRRKFDYWGVPFSELFPNYHAPHTVEWDCGERAKCIKSYRLYQC
                     QTCRKKYTLSYGDYILIDEKGKKR"
     gene            complement(9226..9486)
                     /locus_tag="KB902_001340"
     CDS             complement(9226..9486)
                     /locus_tag="KB902_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808177.1"
                     /translation="MEHYTGLLDKIRVIKTQPLLVRFTLHTSHEPINCVVANIEIADK
                     LLILEEGKYTISVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9561..9764
                     /locus_tag="KB902_001341"
     CDS             9561..9764
                     /locus_tag="KB902_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBB6808178.1"
                     /translation="MIKTVKFVTVAIQLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(9924..10181)
                     /locus_tag="KB902_001342"
     CDS             complement(9924..10181)
                     /locus_tag="KB902_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808179.1"
                     /translation="MAKNISLTMDLLIPVIAFLDGISLGITENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTIAATAVILTAILPLYM"
     gene            complement(10203..10676)
                     /gene="ssb"
                     /locus_tag="KB902_001343"
     CDS             complement(10203..10676)
                     /gene="ssb"
                     /locus_tag="KB902_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6808180.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTNFEQRDTATPNNNGLNPFGGQSIDISDDDLPF"
     gene            complement(10679..11578)
                     /locus_tag="KB902_001344"
     CDS             complement(10679..11578)
                     /locus_tag="KB902_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBB6808181.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            complement(11591..12187)
                     /locus_tag="KB902_001345"
     CDS             complement(11591..12187)
                     /locus_tag="KB902_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBB6808182.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            complement(12268..12417)
                     /locus_tag="KB902_001346"
     CDS             complement(12268..12417)
                     /locus_tag="KB902_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808183.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            complement(12433..14637)
                     /gene="topB"
                     /locus_tag="KB902_001347"
     CDS             complement(12433..14637)
                     /gene="topB"
                     /locus_tag="KB902_001347"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6808184.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEVIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(14648..16108)
                     /locus_tag="KB902_001348"
     CDS             complement(14648..16108)
                     /locus_tag="KB902_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6808185.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEAKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLITELKPKHERQNF
                     LVRDNRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVHCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNASFDQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGRQQERE"
     gene            complement(16169..18541)
                     /locus_tag="KB902_001349"
     CDS             complement(16169..18541)
                     /locus_tag="KB902_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808186.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKVAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQSELQAGIQAVANNIGIQIRDITESEIYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKLSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVQQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         5201 a         3736 c         2987 g         6622 t
ORIGIN      
        1 aattatatta tcttcttgaa ctgttccatg aacattaatt atttttacat agtccctgaa
       61 aggataagta taattaaagg aaaatattgt atctgaaata tttggaagtg aagtagcttg
      121 tgtcattttc aataaaagtt cagcagcctt ctcttcataa gagtaatcaa taatgcttct
      181 taaatattca acaaaataat gttcaaaagt tcttaattca tcatacaaat agtttaaaag
      241 atcttttcgc tcatattctt ctctattagg taaaaatgaa gctaaatgta aacaaagtaa
      301 tgtctcagca ttgaccttat caaaaatacc acgtaaaaga gattctatca ttcttaaatt
      361 aggaaactta gcattttcat ctttagagca aaaaaattct aacatctttt gttctacatc
      421 ttgccattgt aaatcttttt cttttccacc tgaataataa aaaattaaat cccaaaaagt
      481 taaataacta ctttgaatta ttccgtatat atcatgatta cttgttcccc ttaggtttta
      541 cattgttctt cttgcctgtt cgaaacgttc atcaggttct ttaactctaa aaatagtatc
      601 atagccaaaa taagaagaat caaccatttg gcttttaaag caaatcaatg cttcatctaa
      661 ctgtttttta accttttcgt ctattctttc tgaaaaaaaa tgtctatatg ttgattttaa
      721 agtacttgct aaatcaaacc catttcccaa aataatcagc tttttattat tcacaactca
      781 tccacctatt ttattattta ttttacatct ttttgtttct gtctaacttc atcagtaata
      841 ccatatttca ttctatatct tctaaacgtc cttcgattaa tacctgtttg ctcttcaact
      901 tctttatctg tagatccagc taaaaacaaa ttaaatgcta actgcaggcg gggatcattc
      961 tctcgatact tgggttttcc acccttatat ttcccttttg ctttagcaag cgcaatacct
     1021 tgcttctgtg tttcaagtat atatttacgt tcatcttcag cctggtattt atataattca
     1081 ataatcaagt tattaagtaa tcgacggaga ttatcatcgg taatacctgt taacgctggt
     1141 aaattcaaaa cttcaagcgt tgctttcttc aattgaatta aattcattgt ttccgttaat
     1201 tctttattat tacgcccaag acgtttaagt tcggtgacta ccacaatatc atcttcacga
     1261 ataaaattca tcatttcttg aaatgcttct cgatttgtat cctttccact caacttgtca
     1321 gtaaaaattt tatcacagtc agataaaagc tccaattgtc gatctaaatt ttgatctgta
     1381 ctacttactc gtgcatatcc aattttagcc atagaaaaaa ctcctttaaa aatcaaaaat
     1441 tttgatcatt ataaaaatcc tgttgcccaa ctctgttgac ctcttagaaa cccaagtata
     1501 tcatggacac actgtcactt ttctttataa atggcaaaaa ttttaaacgt taaatgacaa
     1561 aaaactaatg agcatttgcc tttccctttt cctttttctc ctccattttt gtcaaataac
     1621 gataaatggt ggttcttgag acgttccaac gttccgcaat agtcttaata ggcgtaccac
     1681 tatccactag agtcttcagt aattctaagt cttgttcagt caatttttca ggacgaccac
     1741 caaatcggcc tcttgcacga gccgccgctc tccctgctgc agagcgttcc aagattagat
     1801 ttcgttcaaa ctcggcaaat gctgcaaaca aatgaaacat tagctgacca gtcgaactag
     1861 atttatccat tgtaatattt tcctgaagac tatgaaaact tacgccgcgt tcattcaatc
     1921 gattaacgat cgaaatcaga tcttccatat tcctacctag acggtctaaa cgccaaacga
     1981 caagtgtatc tccagaacga acaaagtcaa tagccatttc taatcctggt cgcttacttt
     2041 ttgccccact catatgatcg gtaaaaattt tttcacaacc aaatttattt agactgtctt
     2101 cttgcaaatc caaattttgt aaaccagtag atacccgggc gtatcctatt ttcaaaaaaa
     2161 tcactcctaa ctaaaatcta ttgtaacata acttcattca cacggtttaa atgaacatag
     2221 attttgatat gggtttgtga acacaaaatg aattgatttt ttgaaaaata aagtaaaaaa
     2281 acaaagtgtc cagaaatgcc tgattttgtg aacacggaaa aatcactccg acaacaacgg
     2341 ctgtcttctt tcccattgac ggttttacag acctcaaccg taatcgggtg cttgctgcac
     2401 gggatgagtt gcaaacactc gtgactatga caaaagcggt ttggttcact ataataaaac
     2461 ctgaacatcc tctttaaagg ttgttcaggt tttataaatt ttatgacgaa ctactgacaa
     2521 tcagtctttc tatttattaa atttaaacta gctaactaat ttcttattct atcgaatttt
     2581 gaaaatctga agcaatagat cctgtcagta gattctcaat actttggttc attatatcag
     2641 gcaatacgca atcttcacag atataaaaat tcatatcaac cgcgctcaac tccgatacag
     2701 agttcatttt ctaactactt tccatttact cattatttga atcttctgta gaattcactc
     2761 tttttgtttt ctctatagag ttactctttt tagactcctc atactccttt aaaagtctga
     2821 ctaagtcttc tccagaaagt tgttgagtgt ttgtaatctg acttatttcc aaggacattc
     2881 cttttaagtt atacattggt aaactttctt caattttttt tattcttgta tcagatattt
     2941 tctcacctga agttgttaaa taaataattt tattttcttg atcaatcgat ttgttaatga
     3001 caatgacgtt gttacccaat tcttctgaga gcattcgtct taatccattc tcaataatac
     3061 tttttccaac aagttgtgag gcagaaatta tacttgggat cagaataaca atactcagta
     3121 taacaatcac cacattcatc ttactcttct cttcactatc cacctttaca cttttaggaa
     3181 tacgcatgac ttgaacacca atgaacgtag cgataataat gaaaaaacaa ttgattaaaa
     3241 atagatatcc tgctcctaaa aaatagggca ttttttttaa agcaatagca taacctaccg
     3301 tacacaaagg tggcattaaa gctgcagcaa ttgcgacacc ggcaacaata ttattcattg
     3361 ctttttttcg agaacctatg accccagcaa ttcctccaaa gaaagcaata atcacgtccc
     3421 aaattgttgg ttgtgttcgt gcaagaattt cattacttgc ataagaaata ggagaaataa
     3481 aaaaataaat acttgctgtc actatagaaa ccattatttg tactaaaagg atttttaacg
     3541 ctttttttag catttgttgg tcaaaaagag acaaccccat cccgacacct tggataggtg
     3601 tcattagggg ggatacaagc attgctccaa taacaactgg agtagtatcc atattcaagc
     3661 caatacaagc tataacgatt gagcaaacta aaataaccat atcttctctg cggatagtca
     3721 aatcttggtt gattttagca taaaattctt tggcactata atatacattc tcactcatca
     3781 ttttcttcct taactgtaag tttctttatt ttcatattaa attcatagtt attcgtccct
     3841 aattatatca taattaatct ctcgttaagt agaaataggt atgccaaata atcagaaaaa
     3901 tttatgccat ttaaatagaa aagtgacacc acaatattga aaaatctggt tttctcgtgt
     3961 atgattaggg tgtattttaa atagttgcag aaagtaggta aaaattttga gagttgcata
     4021 catacgtgtc tcatcgatcg atcaaaatga acaacgccaa gttgaagaaa tgaaaaaatt
     4081 cggtgcagag agaattttca tcgagaaaca atctggcgct acaattactc atcgacctgt
     4141 tttccaagaa gcattggatt acgtccgaga tcaagatatt tttattgtgg aagctattga
     4201 tcgacttgga agaaattatg acgagatcat cgcttcagtc aattacctaa agaagaaaaa
     4261 tgtgcagctg atcatcacca gtttaccaat catggctgaa gcaattggca atcctcttct
     4321 ggataaattc attaaagatt tgatcattca aattttggcc atgatcgctg agcaggaacg
     4381 gactgaatct aaacgtcgcc aggcacaagg aattaagatt gccaaagcga atggtgttta
     4441 taaaggacgt ccaaaacttt atagtgctaa cgcaaaagat ccccaacgac gcttagtgta
     4501 caaaaacatc gttgaagatc ttaaaaaagg tgttgcgatt gctaaaattg cgaaagaata
     4561 caatgtgacg aggcaaacgg tttatcgcat aaaaaaagaa atatagaggg agaaattagg
     4621 aacatgagca ttgaggaata ctggaacaga cttggcaaac caaaaactat ttatgaccca
     4681 caacaaattg aaaaattttt gaatgtgttt ataaaaaaga ctaatggaaa cttaaattta
     4741 gacacaatcc acaactatga tttcagtgat agcatagtaa aaatagaaag aaacgaaagt
     4801 ttgttcaaaa tttattggaa agactatgaa caagtaatta acaagcactt aagtcattct
     4861 gctactgaag atgaaataga tgaagtaatg atctatggtg gatttacatt tatttattat
     4921 ctaatggata ttcacaaaat ttctatagat aatttacatg gtaatgttta tgtaataatt
     4981 cattgcaatt atttccctga aaaagccgct ataaagcatc tgaaaaaaga ttttaaattt
     5041 gtaaatgatc cgtatacagt atctgaagat aacgcaacta gaaaaaaaat ttatttttct
     5101 gatagtaaca attataacca tgagtgtgtg attgatgtat tgccaatttc taattcaata
     5161 atatttcaaa aaattaagcc ttggaatact agcttctcac acaagcttct aactcgtgca
     5221 gcacttaatg aaataattaa tcccgtgtat aagaataaac agttattctc atctttaaat
     5281 aatgataatg aagataaaat tcgatccatg ataaatgatt tgcgatactc attagagaga
     5341 ttgattaaat tttattttat tactgaatcc ataaaaaacg aatggaatgg attagatctt
     5401 gaaagctcag actctataat tgtagatata ctacagaagt tcggttattc tacattaatt
     5461 aaatttaaaa aaccgttaaa attaaaaggc attaacttaa accaatcttt tataaatgaa
     5521 ttaaataagt attctcatta ctcaggttat tttcctacaa aatctatttt gctgcaatgt
     5581 cacaaaaatt actgtgagat tttagaggaa ctgtttgatt tagctgaata tggcataaat
     5641 atagaagcac tcactatctg taaagaggga gtatcaaaaa cttgaattta tttttgaaat
     5701 atggtgaaag agatacaacc agcttgtatc tctttcatta tgcttcatgt aatattgtac
     5761 tctaaataaa taactaaatg agcctaatta agtgaggtac tgaagaagct cttaaataag
     5821 cagaaaaata agagtcaaaa actttttaag tttctgaccc ttttgagttc taattatttc
     5881 ttccagaacg aagaatgtta tctgctttat ctgcaattga ttctgttaga aggactgaaa
     5941 aatttatgcc agcccttttg cctaacttat ccgcccattg aggaattgtt aaggtttttt
     6001 tgacaagttc tgtgtctttc aaatatttgg caacatctac acgaattaaa gtagtaaaag
     6061 aatcatcttc aacagaaatc ttattgattg gtgttggttc tggaagtaga tcttcatgct
     6121 caatataatc tgctaaaacc atacctaaca cctcttgtgc catagcaatc ccataagata
     6181 tatcgtcttc gttaattcct gtgtaagcac cttgaacatc aggaaattca ataaagtacc
     6241 caccaccttc ttctgggcta aaaatagcag gataggtttt tgctaaaggc tcacttaaca
     6301 tttcagtcaa tcctttcttt aagcgaatgc gagattattt caatcccgca tccttcaaaa
     6361 tttttcgctc aagtcctcgg ccaagatctt gattggcatg aacaggaaca gtgattctaa
     6421 caccatcctt ataaagatga tgatgagatc cctcttgcct tcgctcaacc cagccatttt
     6481 ttttcaataa cttaagcatt tcttttcccg taagtggcat tgtgcactat acctccttac
     6541 aaaataatta taacacgtat tagcacgtgc gtaaagtgct atcactttta gattttagga
     6601 taaaaagtgt catcactttc ttagcgctgg tacctcaaat cccgcttttt cttgtgcgat
     6661 caatagatct aacgcaatac acataatctt agattcactt tttccgtact tttgtttgag
     6721 ttgctgcaat tctttttgtc tcttttcatc taatgtgacg ggtaaacgtt tatttccatt
     6781 ggcaattggc atggtttgtc tcccctttca tcgaaacagc cccaggaaaa atatggctgc
     6841 gattaactta aatattagac tcacgagggc taacacaaac cgccaaaaga tcaaacaaaa
     6901 cactaatatt cctacaaata ataagaaatt tccatgaaca acaacgctat gacgcataag
     6961 cgtttctccg acaaatagta ctaacaatag aggaatgatt ttatacatat gaatctcctt
     7021 atttctctta ggttatcggg cttggtccgc ttatttcgca ccacctaagc gacgggggcg
     7081 gttggagtga ttggtgcgaa ataagaacca ttcccttaat ttcaaggttt tttgttctta
     7141 tttcacacat tctcactttt cggtataaat ggttattgac cttttttcct ttcaaatcgt
     7201 tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc gtcgtaagtg
     7261 taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt atctacttct
     7321 tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat tcccattaac
     7381 acgatagatt ccgtcccaca cgttaggaat ctagtaaata cgagataata atcgtctacc
     7441 gtcgcatctt tgctgtttag ttcttccatt tcttcttcca ttaattccat gctctcaaaa
     7501 attgaataat attccgataa tgagtaatag tgtttcctgc aaatcgtgta gctgacaaag
     7561 ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc tgtttctagt
     7621 cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac gtctaaataa
     7681 ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa ttgttcttcg
     7741 actctttgaa taaagtactt catttcttcc atacaactaa agtctttttg aattcgtctg
     7801 attacttcat tcaaatgttc tttgtttgtt aaaaagtgag aaacatcttc cattgttagt
     7861 tgataaacca ccttattcat tttcgttgtc ctcctttttc atgatgtaac atgcgccata
     7921 cttattgaca ttttcaaagt agtccgacca ttcacttgaa acagtcttgg cttttttcgt
     7981 ttcgacaaat tttgcatacg ttagttctaa agcttggtat tcagaaggtt tgattgtgct
     8041 tggtttgacg cctgcttcca agcatagtaa ggcttggaaa aaccacttgt tattttgctt
     8101 tttcagctct tccagtgttc gatagtacgt cgcaatgaga ttcatttcta cacctgattc
     8161 aatcatttct tccacagcta ccgacaattt ttctttataa tgtttttttg gaacacgtgt
     8221 ttcattgtac aggaacgtca tatcctccat tttttgagcc attttatcca aaggtaattt
     8281 gacaaattcg tcatagtaat tttgagccat attttttctc ctttttagtt ctctaatttt
     8341 gttaaccaat attcgttttc ataagtttcc atgttttctt gataatgcag ttcatatcct
     8401 gcaatcttca ctaggtcttc aaatagcata ttcggtgcat cctctactaa agaggtttct
     8461 atcgtccagt accgcggaat aagtaaagct tctgctactt tttcagaaat gacttctttg
     8521 tccaccaaaa tttgaacgac ttcttttaca gtcaataatt tgtgttgtgt tttcatcagc
     8581 gtttctttcc tttttcatca atcaaaatat aatcgccata agacaaggtg tatttttttc
     8641 tgcatgtttg acattgatac aaacgatagc ttttgataca tttcgctctt tctccacaat
     8701 cccattcgac agtatgtggc gcatggtagt ttgggaataa ttcgctgaat ggaacacccc
     8761 aataatcaaa tttccttcgc atgattgatt ctgcctcctc ttaggaaagg gtttacttcc
     8821 ttttgttagt tctttcttta ttgatttgtt ggccagaatg aatcagcgaa aagcgacaag
     8881 gacaagggcg cgcagcgtgc catttaccct tgtccttgtc gctttttggt gataaaaggc
     8941 aacttgttgc cggtctggca aatcaataaa gagatagcga acaggaacga accttttggt
     9001 gagaggaagt ttttcctatt ttgtcttgct ttgcaagacc ccttatctta gtgaacgtgc
     9061 agcgttcact tcctttcttc tcgaacggcg gtggcggttg gagtgagaga gaggtttttc
     9121 aattgagaag gcgcttgtgc cttcctaaac aggccttttc attcttactg tttctatgta
     9181 aaacaaaaag agctgcaatc ctcatttagg actgcagctc ttcttttata tgcccatcga
     9241 tcgcgtaaaa tgatcagggt ttctaatttg cattgattca atgactagtt gatttcgttt
     9301 attgaagtga cctgtcactg aaatagtata cttgccttct tccaaaatca gcaatttatc
     9361 cgctatttct atattggcca ctacacaatt gattggttca tgactcgtgt gtaatgtaaa
     9421 tcgcacaagc aatggctgtg tcttgatcac ccgaatttta tcgagtaaac cagtataatg
     9481 ttccatcgcg atcacctcgc taaaattata gcaaaaacag ctaaaattga gaatttttat
     9541 tcgattttag atatgctata atgatcaaga cagtaaagtt tgtgacggtg gctatccaat
     9601 tgaaagtgag gtggtgcgta tgtgcgtact tccaaaatct tacagaaagg agaagccttt
     9661 tgcctgttga aacggcgcta ggattaatga ttagtttcgg ttctttgatc gcaacaatca
     9721 tttttggaat cttagcagtt gtaaacaaca atcaaaaaaa ataaccgtca gctttagccg
     9781 gtcgacgatt attttttaaa aataatatta agctggtcac cgtcttaaac ggtgctgtta
     9841 atgaggggtt gttagcgcaa ctcctctttt tcatgttcat tatagcaata tttcgcaaga
     9901 agttcaacga tttcccgtta accctacata taaagcggta gaatagccgt aagtataaca
     9961 gctgtcgcag ctattgtgac tttagtcaat cgccaaaagg aattatcctt tcctgctctt
    10021 ttaagaagat aagaacagac aagatacacg aatacaagaa atagtgatcc ttttgcaatt
    10081 ctatttacca aaggattttc agtgataccc aaagaaatcc cgtctagaaa tgcaataacg
    10141 ggtatcaata gatccatcgt cagactaata ttttttgcca tgcttactcc ttctttctcg
    10201 aactaaaacg gtagatcatc atcgctaata tcgattgatt gtccaccaaa tggattcaat
    10261 ccattgttat taggcgtcgc tgtatcccgt tgttcaaaat tggtggtgct tggactggtg
    10321 gacgattgat cagcgtgcgc acggctctct gtcgctgctt tactttctaa tagttgaaag
    10381 ttatctgcta caacttcagt cacatacaca cgttgtcctt gttggttatc gtaggttcgg
    10441 gtttgaatcc gtccgacaac gccgatcaaa ctgccttttt tagctaatgt cgccatcgtt
    10501 tctgctggtt tgcgccaaat cacacagtta ataaaatcag cttctcgatt gccgttttga
    10561 ttcgtgaaat ttcggttgac ggctagggta aaagtcgcta ctgcagtacc acttgcggta
    10621 taacgtaaat ctggatcttt ggttaaacgt cctactaaag ttacattatt gatcatcttt
    10681 atctctccat ttctctattc atctgttggt gtctttgata agctagtttt cgctcttttt
    10741 cttcgacgtg aatcactttt tccatcaaat tactaatcga atccattgtc tcatcgtacg
    10801 tgatcgacgc agcataagga ttgctttttt gatatttctt ccaagtatct tttagctcgt
    10861 gactattttt cagtacatcc atatcctttt catagtaaat ctttaacgga tcagtttttc
    10921 ctcgacgtgt aaatgtattt ctcacactat ctttcaaggt cttctcatcg atcttctcca
    10981 ttttaggaat agtatagaga tcataaaaat cttttcctct cgaattatct gttaaaaaat
    11041 caaaggttgc acttaatttt tcagcaataa tttgttctgt aggataggat tccaaaggaa
    11101 tcgttcgatc ctcaaacatc aatttatgac tgtgagtgat cgttgcagga tagatcgagt
    11161 cacctgtcgt cacatctacc ttaaaatctg gccgcatgtt ttccaaatgt gccagcacac
    11221 gtaagctaaa tcctggatag taatcggctt ctctcgtttc tttcattcct tgaatctcaa
    11281 attgaatgcc ttctttcgtc ggcgttgaaa aaatatcgtt tagaaccgtt gttaatgttt
    11341 ctttggttac tttcatttcc cgtaaagtcg tatcaatgtc tttggttgtg cgattttcaa
    11401 tgccgtactt tgagccaatt aagaagccgc cttttaacac aaaattttca cgataaggag
    11461 actctgagat tttttccaag aatttttcca tcataaaatg tcttaaaaca agctgcggat
    11521 caacttcttt ttctctggaa atattcttca cttttgcttt taactgcgta ggtgtcatgt
    11581 atcttctcct ttaatttaaa gccataatat aagaacgcat cgttttgtct gttggcaaaa
    11641 ttcgtcgata ctcattcaat tttctaagat tttttctgtc cgactccatg tagtttttga
    11701 ttgcttttac tttgatttca tcctcaacgg tataccaggg attccaaatg tcacacaaag
    11761 ttctttctgg atcataagct ataataggat tcccatagcg actttttatt tcaatcttac
    11821 ctaattcata ccattccgct tttgtatagt gtagctcaac tgcgaattcc ttcaatcctt
    11881 tttcagaaac gtgataaccg taaggtacag tcagatcgat ctgtctaggg atcatatctg
    11941 ttaaatcata caaatctaac gcggtaatat gtgaaataat gccgcgttca tatttttttt
    12001 gcgccataaa caattcatca ggaaattgac caggtaaggt gaaaaaacct ggatactctc
    12061 gatccagttc ccctcgatct accatacgtt tgatcgttac aggagaaatg cccgcttttt
    12121 tggcatcctt caaagccaaa gttccattaa attcttctag cagcttgtat accattgctt
    12181 ttgtcatttt ctccctcctt tgtatacgta taaacttata aatatagtat aacataagtt
    12241 tatacgtata caacagccag gaagatttta tcgatctaat tcgatttctt tttgaatccg
    12301 ctgctggttc ttcaattgct gaagtcttct tttactggca cgtaatttct cttgttctga
    12361 acgaattttt gctttttgat tttcgatttc ttgttgtttg tgtgttgtat ttcgcataag
    12421 ataacccctc cattattttg tagtgcggcg tgttcttttc ttatagttcg tttttttctt
    12481 ttcagaaaat tcaaagcctg tagtgaagtc ttcttttaaa acaatcgttg cttcaaacga
    12541 acccttctga ccttttaacc ctttcactgg ttggcttgtt cggctatttt gaataatctc
    12601 cttcagctgt gtcgctgtga gtttcttttt ggcaatcgtt gtccataatt taaaatcaca
    12661 ggcttcagac gtacaagctg ccaccttttg atagagtaag acttcttgtt cctggcattt
    12721 tggacaaatt cctaaatgac gcgcggcttc ttgcttttca ctggctgctt tcacttcttg
    12781 taacgtcgat ccaaaatcaa tggattggat ttgtcctggg acgacttcca ataagtgaga
    12841 gacaaacttt tggatattgg ctagaaaagt ggtttgtgtt ccttttcgtt ctccaatctt
    12901 taacaagtag ctttcccatt tggcggtcat ttcggcactc gtaagcagcg gctctttttc
    12961 cacagcttgg caaagcaaaa cccctttatt cgtcaccaca agcttatttt tctctacctt
    13021 gatatattcc ttttgtttca aggtttcaat aatattcgcc cgtgtcgctt ctgtaccgat
    13081 tacttccact tctttcaata tggattgcgc ttcttcacta tccacggttt tcccagctgt
    13141 tttcatcgca gtgatcaacg taccttcggt ataaggttgt ggtggcttgg tttctttctc
    13201 aaggacttgt agatctaccg tcaccatttc tccttttgtc actttaggaa gtagcggctc
    13261 ttcttccttc tcttttccgt cgctctcttt gccaaataac ttcttccaac ctagatctat
    13321 cggtactttt ccgattgcct ttaactgaag ctgctggact tgcgtcaaga tcgttgtttc
    13381 ttcataggta tatttttccg caaacatcgc cactgtcgtt tttaaaactt gctcgtaaat
    13441 cgcttgttgt aaaggtgtca gactttcata cgtcgcttct gtcataactg tttttgtagg
    13501 aatgattgcg taatgttcct ggactttctt gttgttcacg tacctactat tcggtgtatg
    13561 aataggagtc gaaatttctt cagccctcaa aaaatgcttg tattcgtcta agtgatccaa
    13621 cagatacgca tattcccctt ccgtaatgta aggggtatcc gttcgcggat agcttagata
    13681 tttcccttca tacaagcctt gcatggcttc caaagtgtct ttggcactag ctttcatgag
    13741 ctgattcatt ttagactgaa ggctggatag agaaaaaaga cgtggacttg ccgcgctttt
    13801 tttctcggtt tcaacttggc gaatcatgcc tggctgtttt cccaattgaa cccccttttc
    13861 ttttaaataa tcttcaaatg cttcttgcgt cgcttgggtt tcattcggat caagcttcgc
    13921 atcaaatgcg ccattttgag cgattacttc ggattttcct tcaaaataag gttctttctt
    13981 gaaatttcta atcttttcct gcaattgata aatcatgtaa agcgttgggg tttggactct
    14041 gcctaaggaa aagcttcctg gtatgccttt ttgctgcaag agtaaactat acagtgggct
    14101 accgttcatc ccaattaacc aatcggcgat ctgacgtgct tgtgcttctt caaattttgg
    14161 ataggtctct tttgcgtctc gtaactgctg gaatccctga taaatggctt ctttttctaa
    14221 ggagttgatc caaagtcttt taaaggtttt tccttgatcg gcgcctactt gttgaatgat
    14281 cgtccaagcg atcagttccc cttcacgatc gctatctgtc gcaataataa tggtgtcggc
    14341 cgattgaagt tgctgtttca ccaccttgaa ttgctttttc ttatctttag gaacatgata
    14401 gtgataatgt gtagggaaaa taggcaaatg ttctaatgac cattgtttcc aattttcatc
    14461 gtacatatcg ggcgaatcta attcgactaa atgaccaaaa ccatacgtga tcacagtttc
    14521 accaggaaac aatcgatctt ggatttcaaa atacccgtct tttcgagtgg ctttagagaa
    14581 gctatcggca taagctttcg cttgtgacgg cttttctgct aaaatgacag ttttcatcgt
    14641 gacgatctca ctccctttct tgttgtctgc cttgttgaaa caacatcgca cgtttttgct
    14701 ttctgatctc ttgttggtgg atttcatgct tcaattgatc attccaatcc ttttttactt
    14761 caggtacaaa ttcatgttca tgatttttat agcctttgta gtattgttct gctttataag
    14821 agaaaagaat ctgagcatta atatcccctt tttcttgata aaaacgatca aaatcgtacg
    14881 taccatccac gcgttcacaa ccttttaatt cttttgcgac ttctctacaa atatctttca
    14941 aattaatagc ttctattgaa tcgttaacag aaagctgctg gtcaaaagac gcattgactt
    15001 tgtgagcgga aaccagttgg ttcgttaatt gcagattgtt ttctgtcttg tgtatggcca
    15061 taatagcttc tggtgtgacc ttttcttctt ttgcgacttc ttcataaatg attttgtatt
    15121 cttttggcac ttgccaatca ttagcgattc ctcgttcaca atgtactttc tgattcgtaa
    15181 atggatcgac tgcgcccatt aattgttcct tttcgtagaa aatatgtcct gcacgatcat
    15241 tatccacaca aatctcaatc gattgaggaa aggcttgttt ctttctcaat tcagatactg
    15301 cctcaccaaa ataatgactg atcacatggt gttttaaccc ttccatagag actaaccacg
    15361 tatcgtttaa ctgatcacga ttcagtgcag cgtagctaag taaatcaata ctactctcaa
    15421 aaaattttaa ctgcttaggg tcaccgatct ttaggttaaa gccatgattc gctgtcgaat
    15481 ttttatctat atgcttatat gttcctctct caccaaaacg ttcataatca ataaacgttc
    15541 cttgataact cgcccccaca gtctcttttg tctgtggatc tttccataaa aaggcaactg
    15601 catgatctaa acgattgtct cgaactaaaa aattttgccg ttcatgtttt ggctttagtt
    15661 cagtaatcaa tccttctttt tctgcataat caatcagcca ctctggcaat tttcgttctt
    15721 ccttcagata attccttcct ttttctgtaa gtggttgata atcaacgggg tgatctttgt
    15781 acttttctgt ctcaaaatga agattttcta ctcgttctgt tttggcttca ttctttagaa
    15841 taaaatcagt ggctgcttta aattgttgct tagggtcttg gatctctttg tctataaaaa
    15901 aaagtttagc taattcaata atgtcgccac taatattttg actattccaa taaaaacgtt
    15961 gttttcttcg atcgaaaaca aacgaatcat ggtcttctaa gcgatagtca cgtcctttat
    16021 tgactacagc cattccattg tttcgtgcaa aatccacaat atccatttgc ttgcatcgat
    16081 caatgagact catttttttc tctgtcattt tcaaacctcc caaaagaaaa aagactatcc
    16141 atttttcaga tagtctttct tacttgtttt atacgcgttc tttttgtgac aattgttgtt
    16201 cataatagat ttcatttttt cgtttggcca cttctgacac tgtctcaagt gaaaatcgga
    16261 atggatttcc tagcgcaaat tcttctgaag gtaacgccgt ttggatctct tttccataac
    16321 tttttccttt taaaattact tgattatgct gcggatcttc aataaacgcc gcatccttca
    16381 aatgtaacgt tcgacccgta tcttcttcca ttactttccc gtctttcttg tcgatccaaa
    16441 gtgaaccaac aggcacaata ttcttttgtt ctgccgtttc tacagtattt ttatgctcct
    16501 gctgcacttc tgctggttgg atctctggtt ctctttctct gtattgattg atttcattag
    16561 aaatggtttg aatgaattca tttgcgacac ggctgacatc attcatgatt ttcccacgtt
    16621 ccgcagcttc cttatcatcc aacgtctgac cattcttcgt ccatgctgca atataaggaa
    16681 tagctttctc cgacgtgtcc attccaaaat gtttgcacac aatataagaa gtcatttctg
    16741 cctgcaattc tttagttgcg gtatctaatt ctgaaagttt gtgcattctt gcatgggcta
    16801 attcatgaat acttgtagct aaatgctgcg taggagtatt tcgagtattc atgacgattt
    16861 cttcttcgcc agtaaattcg ttacgaacat acgccccacg tgcttgtcct aattctcttt
    16921 gatagatttc actctccgta atatctcgaa tttgaatccc gatattgttg gctaccgctt
    16981 gaatcccagc ttgaagttct gactgccctg tttgatccaa ttgaaaatca aagacacggt
    17041 tcgggaagat tttcggatag tcttcaggtt ttaactgagt ttgtgtgata tcaaacactt
    17101 tttcaatcgt gtagtaaggt tttttgatca cttcgatttg accactttcg attcgttttt
    17161 tatcttctgg tgtagcttct gtttctcgaa caaagccacg tcctttctca taaaatcctt
    17221 tgaccgtttt tctgacaaag atcttgttcc cttgttcccc ttttttgata tagattcctt
    17281 cttttttcaa cgcggcacga cctaaacaag ccgttgcacc tggaaattgt tcctcaatca
    17341 ataattgatt tctaaaggat cgttctggaa aacgagacat aaagttcaaa agttctttga
    17401 cgtcttcagg agaatgggta tgctttttca ccgcatccag tgcctgttgc gaaagtgatt
    17461 taacttcttg tttaatctct tctgccgttc gtttttgata tcccttttgt tttgtttttg
    17521 tttctttcga ctgcatttgt tctttcgaaa caggttcatt tttgaccgtt tgtttttgtt
    17581 ccttctcagg tacttgttcg cacaattttg ctaactctaa atagatgggt tgattactgt
    17641 tgacgccatc ccctagatcc attcggatct gatcgactac ttctccgttc ttcacttctt
    17701 caaaatagaa tttataataa cctgcttctg cagcgtattg gttgtccaac gttttgagtt
    17761 gatcgatcaa ttctaatgtt acgatctctc caccataact tttcaatcct ttttctggat
    17821 cattttcgtt gaattctact cgatagaaat gatcgttttc tttctccttc agagaatcag
    17881 ttggcgcagc ctcttcaagt aattcacgaa cagctacttt ttcctcttcc gatgtggctt
    17941 ggtatttttt agattcctca aattccccgt tttcattcag ttctaaagcg acttttcgat
    18001 agcctttcag aaaataaatg gtcggatttt ttttccattg cgttactcgt ccgctgtcaa
    18061 tgatcgcttg tacttcaggg aggatatttt cttttccttt ttctgatttt tctttcagct
    18121 gttctaatgt ttccaacttc cgttgatatt ttcggatcgt ggcggctgaa aaagacgatt
    18181 cacctttttc aaagcgttcg atttcttctc tgattcttgg aatattttcg atcgtcatat
    18241 ctagtccgcc gtacttgtta taacccattt cctttagctc ttcttgtctt tcaagttttt
    18301 ctacctgttt ttcttgttgc ttgatctctt ctctcagact ttggacttta ttttcgattc
    18361 gttcttgctg gttaaaccat gaacggccat tcctcttgtc gttcattggt tgaccgttcg
    18421 tcattttttg gtgttcaaac atcttttcga tttgttcatt taattcattt tgcaatcgta
    18481 ctaattttct tttggatttt cccaaacgac tattgtctag tggttctttt tcttctgcca
    18541 tgtccg
//
LOCUS       DADVXB010000051        18171 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.052, whole genome shotgun sequence.
ACCESSION   DADVXB010000051 DADVXB010000000
VERSION     DADVXB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.052"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            35..517
                     /locus_tag="KB902_001350"
     CDS             35..517
                     /locus_tag="KB902_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808187.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            714..1604
                     /locus_tag="KB902_001351"
     CDS             714..1604
                     /locus_tag="KB902_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBB6808188.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            1930..4401
                     /locus_tag="KB902_001352"
     CDS             1930..4401
                     /locus_tag="KB902_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6808189.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(4504..6240)
                     /locus_tag="KB902_001353"
     CDS             complement(4504..6240)
                     /locus_tag="KB902_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBB6808190.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6237..6941)
                     /locus_tag="KB902_001354"
     CDS             complement(6237..6941)
                     /locus_tag="KB902_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808191.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7072..7575
                     /locus_tag="KB902_001355"
     CDS             7072..7575
                     /locus_tag="KB902_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBB6808192.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7535..7873
                     /locus_tag="KB902_001356"
     CDS             7535..7873
                     /locus_tag="KB902_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBB6808193.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7894..9312
                     /gene="ffh"
                     /locus_tag="KB902_001357"
     CDS             7894..9312
                     /gene="ffh"
                     /locus_tag="KB902_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBB6808194.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9424..10002
                     /locus_tag="KB902_001358"
     CDS             9424..10002
                     /locus_tag="KB902_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBB6808195.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10006..10527
                     /locus_tag="KB902_001359"
     CDS             10006..10527
                     /locus_tag="KB902_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6808196.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10606..11160)
                     /locus_tag="KB902_001360"
     CDS             complement(10606..11160)
                     /locus_tag="KB902_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6808197.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11413..11688
                     /gene="rpsP"
                     /locus_tag="KB902_001361"
     CDS             11413..11688
                     /gene="rpsP"
                     /locus_tag="KB902_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBB6808198.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11700..11951
                     /locus_tag="KB902_001362"
     CDS             11700..11951
                     /locus_tag="KB902_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBB6808199.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12076..12867
                     /locus_tag="KB902_001363"
     CDS             12076..12867
                     /locus_tag="KB902_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808200.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13037..13558
                     /gene="rimM"
                     /locus_tag="KB902_001364"
     CDS             13037..13558
                     /gene="rimM"
                     /locus_tag="KB902_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBB6808201.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13548..14309
                     /gene="trmD"
                     /locus_tag="KB902_001365"
     CDS             13548..14309
                     /gene="trmD"
                     /locus_tag="KB902_001365"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBB6808202.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14445..14792
                     /gene="rplS"
                     /locus_tag="KB902_001366"
     CDS             14445..14792
                     /gene="rplS"
                     /locus_tag="KB902_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBB6808203.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(14924..16060)
                     /locus_tag="KB902_001367"
     CDS             complement(14924..16060)
                     /locus_tag="KB902_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6808204.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVNFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(16176..17090)
                     /locus_tag="KB902_001368"
     CDS             complement(16176..17090)
                     /locus_tag="KB902_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6808205.1"
                     /translation="MKKIVFGLLFLGLVLSGCSTSPNSASTKENTVSSTSEYETKKLT
                     SSDVHKIKVGDDLTQVYQTLGSPLRKWTNDFVYKELDNAITRDELIVSISKDAQGDYY
                     KEHSELIEHGNSAKDIKKLEMLQYTYSTDSDDETMLIWVSPKTEQVVYYNQRTFLDKD
                     GKSKDSSSTTTTTTTSSSEPQTASVAHSIGEAVPFTSENGNSINVTVQSVSKDYGDDF
                     YKPEGLFYAKVDFLVENTGTTPFDASSSYLEFYDSSDIKSDLASRDYFSETIQPGKSA
                     QGTAYFEVKNDGTTFEVFFADTSWKGSY"
     gene            complement(17181..17609)
                     /locus_tag="KB902_001369"
     CDS             complement(17181..17609)
                     /locus_tag="KB902_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6808206.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(17614..17988)
                     /locus_tag="KB902_001370"
     CDS             complement(17614..17988)
                     /locus_tag="KB902_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808207.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
BASE COUNT         5875 a         3261 c         3597 g         5438 t
ORIGIN      
        1 atgatgagag aaaaagtagt ttgggggaac gttaatgaga agaaaagcag taatcgatcg
       61 gctttattta tttttttggt tttttcctat cgttttgcta ccttttacat gggtaaatgc
      121 tgttgtacaa ggtgcggaga tattaggcct gatccaagga agcggattag tggtttctag
      181 gaattttcca gctttgactg ttttctattt agtgataagt gtaggtctct tattaccaaa
      241 atctctgatc aatcactaca attggcagct gctttacttt tcttgcttat tagtatttac
      301 atctatgttt tctttgctgc ctcgcttgat tatcggccct aatggtttga gcgagagtgg
      361 attgaaggat tcagcttatt cctccatgta tttcttgacg atcaaaccat ggttctattt
      421 agtaattgcc tcatttattc ttgcaacatt tttttacttc tggacagaaa tcaggataaa
      481 aagtgaacga tctgtatcta taaaaaataa ctattgatgg tggatcatca gtaaaaaagc
      541 atatgagctg cgtaaaatgc atgtttctca tatgcttttt ttattattat gtaaagaatg
      601 cgaaaaacgt ttacatgatt tttacataac ttaactatat ttttacagca accatacgag
      661 ggatttacag tcgactgata aactttagtt gtaaataaga aaggagcaat aaaatgaaaa
      721 aagtattgtt tactctaggt atgatgggaa ttcttttagc cggatgcggc tcaggatcag
      781 gaaatacaga tggctctgcc acacaaaata attcaagtga ctcaaatgaa caagtaaaaa
      841 tcgttgcggt aggttcgaca gcattacagc cgttagtcga tgcagcacaa gaaagctttg
      901 tacaagaaaa tccaaattat caaatctctg tacaaggagg aggaagcgga actggtttga
      961 gccaagtcga agctggagca gttactatcg gaaactctga tgtatttgca gaagaaagag
     1021 acggagttga tgcttcaaaa ttagtggatc ataaagtagc agtggtcggg atggcaccaa
     1081 tcgtcaataa agatacagat gtcaaagata tcaccaaaca ggaattgatt gatatcttta
     1141 caggaaaaat cactaactgg aaggaagttg gcgggaaaga tcaaaaaatc aacgtcgtga
     1201 accgtgcaaa cggcagcggt acccgcgcga cattcgaaaa atggggactg gatggtgcta
     1261 cccctgtgca gtcccaagaa caagattcat caggaacagt tcggcagctg gtaagtcaaa
     1321 caccaggagc aatcagctat ttagctttct catatctcga tgattccaca caagcactaa
     1381 gtatcgacgg tgtagaacca aaagaagaga atgtagcaga taacagctgg ggaatctggt
     1441 catatgaaca tatgtacacg aacggaaaac cttcccctga agtccaaaaa ttcttagact
     1501 acatgatgac agaagaaatc caagaaggac ctgtcaaaga attgggctat ttaccaatca
     1561 caatgatgga agtagaacgt gatcacgaag gaaatatcaa ataactagca gataaacatg
     1621 ccacggtagt cgttactatt aaggaaaaat caactatgtt tccccacata tacatttttc
     1681 ctttaattgt gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     1741 agctgattga acaccgttta ttcgaaaaaa agagctacga catagaactg tcgtagcttt
     1801 ttttttgcta tatgacagga atgaaaggtg tttgcaagct taatgtgagg aacactttcc
     1861 atatctgttc tatactggat aggagaagtt tggaaatatc cagaaaacga aatcaatcga
     1921 ggtagccaca tgaagaataa atggataaat cgaagtaaaa aaaagaaagt aacacaaaga
     1981 tcatcagata aagtcatccg tctttttcca tcgtataaag aaggattaac ggcagatcaa
     2041 gtcaaggaac gaatagaaaa aggtgcagca aataattcag tcgatcccac attcaaaaca
     2101 aatcagcaaa tcgtattgga aaacatattt acgtatttca atttgatctt tcttatctta
     2161 gccattttgc tttgtttagt agaatcctat aagaacttga cttttttacc agttatcata
     2221 gccaatacag gaatcgccat ttttcaggaa attcgatcca aaaagatctt ggacgaacta
     2281 aatgttttaa atacagcaaa agtcaatgtc atacgagacg ggatagaaca aacaatagat
     2341 atagaagacc ttgtaataga tgacattgtt attttagaga ctggatatca aattccagca
     2401 gatgcagagg tcgtggaagg gaaactgcaa gttaatgagg ctttattgac aggcgaagca
     2461 gatgaaataa ccaaagaaat aggtgatcca ttaatgtccg gcagtttcat tgtttccgga
     2521 aaagcttacg cccgattaga caaagttgga gcagattcgt atatttccca gctgacagtc
     2581 aaagccaaga caatgggaga aggagaacag tcggagatga ttgcttctct taatcaattg
     2641 atcaaatgga ttgggatcat cattattcct atcggtatcc tgcttttttc tcaaagttac
     2701 ttttttaatg gaaacacgat caaagaaagt gtcgttgcaa tggaagcagc attgatcggt
     2761 atgatacctg aaggactgta cttgctgacg acgattgcat tagcattaag tgcgactaaa
     2821 ctagcaaagc aaagagttct tttacacaat atgaaaagca ttgagacatt ggcaagggta
     2881 aatgtccttt gtgtagataa aacaggaacg atcacagaaa ataaaatgtc tgttcaaaaa
     2941 atgatcgtct ctaaaaaaca agaaataatc agtcagtcag atcaattgga agcatgcatt
     3001 gctgactatg caaaagcgat ggcaggagac aatgcaacaa tggaagctgt taaagcatat
     3061 tttacaaaaa ccactgatca atcctatcac catgttattc ctttttcttc tgtccaaaaa
     3121 ttcagcagtg tagcgttggc agacaaggtg tatgttttag gagcgcccga aatggttttg
     3181 cgcgatcaat tgccggaata tgcggaagag tttgtttctt tcgctgaaaa aggctatcgc
     3241 gtgttggtct ttggtgtgta cgatgggatt cttgaagaac cagtattgac agaagcagtc
     3301 acaccattag gctatattct gattgctaat cctatcagaa aagaagcaag agccacattt
     3361 gattacttca aaaaacagca agtagccatc aaagtgattt ctggagataa tccgctcacc
     3421 gtatccaatg tagctgtcca agcagggatt tcacatgctg atcagtacgt tgatgcatct
     3481 aaattatcag aagaagaata tgaagcagct gtcgaaaaat atacagtttt tggacgcgtc
     3541 aagccagaac aaaagaaaat cttcgttcaa ttgataaagc gtaacaatac agtagctatg
     3601 acaggtgatg gcgtgaatga tattctagcc atgaaagaag cagactgcag tatagcgatg
     3661 gcttccggaa atgaagccgc catgcaggcc tcacaagtgg tcttacttga ttctgacttt
     3721 tcacgcatgc cagaagttgt tgcagaagga cggcgcgttg tgaacaatat tgagcgatca
     3781 gccagcttgt ttttagtgaa gaatattttc tcctttttgc tctcactgtt ttcagtgatc
     3841 tttgctctga cctatccttt agaaccatca caaatcacat tgattagttt gtttactatc
     3901 ggacttccat ctttcttgct tgctctagaa gaaaacaaaa agcgaatcag agggaaattc
     3961 atcatgaatg tgatggaaaa agctgtgcca ggtggactaa cagatatgat cgtagtcggt
     4021 gcgttggtga tctgcggggt gactttgaat ctaaataaaa cagatgtttc tacagcatct
     4081 accatgcttt tgattgcagt agggttcctc gttctctata aaatctgttc accgctgaat
     4141 aaattcagaa gtcagatcat tcttttctgt gctagcggta actttttttc ggtcatcttt
     4201 ttgcataagc tgttttcaat caccggtatc tcagctgtat cacttttgct gttgagcatt
     4261 ctatttttct cggcagattc gatttttagg catttgacca cattggtaga atatttgttt
     4321 gaacgtaaaa atgaaaaaga gcaaaagccg tttagtcgcg tagctaaaaa atttctatcg
     4381 atatttaaac gagaaaattg acgaaaagta tctcaaaaaa gagtaaaaaa gaacaaccac
     4441 tcgtgtatct ttcgaagcag gatgagtcat ccaactttaa aacgcacgag cagttgctct
     4501 tttttacatt ttcggaatgg taacggtgaa agtcgaacct gttccaagat gactgtctac
     4561 agtaatcgta ccattaagga gttgcacgta gtcttttaca atcgctaacc ctaatccggt
     4621 cccgcctgaa tgtcggcttc gcgccttgtc tacgcggtaa aaacgctcaa agatccgttc
     4681 ctgatcctca atgtcgatac ctataccaaa gtcttggaca gaaaacgata gatcatctgt
     4741 tgcctgatag cggataataa tctcgctgtc gctttttgaa tattggacag cattttcaat
     4801 cagatttttg ataattggat aaaggatatc tgttttagta gtaaatggtt cgttctttcc
     4861 aatcaatcga atcgtcaacc gtttcttttc gatgattggc tgataatttt gaacgatttg
     4921 ctggaaataa ggttctgtat aaattgtctg gatctcgtaa gaattctcgc catcttttga
     4981 cagctggatg atttcccgaa tcagtttatc taaccggatc gcatcttttt gcatgatctc
     5041 aagaaaagaa gtcagagttt gcgggtcatc ttttgcacca tccagtaaag tctcggtaaa
     5101 accaatcagt gaagtcacag gagtttttaa ttcgtgagag acgttgccaa cgaaatcctt
     5161 ttgtagcttt tctaaacgtc gcactttcgt taagtcatac gccaccccta gaatctgtcc
     5221 ggtaccttct gaattagtaa agtagcgcaa actcaagtct aatgtctgcc gaccttctgt
     5281 aagggtgatc tcctgatgga tcagcggatg ctcaggagtc acttgatgaa tcagctgaat
     5341 gagttttggc tcttgaatga cttctgtgta ccgctgttca ggttgatagc ttaccacgtt
     5401 taaatgtagc tgcatctttg gattaagcag tagtaaacga gaatcagcat catcaatcag
     5461 gaatacgcca atcatcagtt cgttcagtaa cgtatataat tgctcttctg tggtagtaca
     5521 cgcccgatac atcttactca tttgttcgct caacgcatta atcgtctgat acaattcttc
     5581 ccattgatcg ggtgtttgca tgattacttc cgcctgatta ggattttgca ccattttttt
     5641 tagtacgggc agcacggttt tcaatggctg gtttttttga tagatcagat aatagatcat
     5701 tcctgcaaga acaaggaaga aagacagaaa gaagaaaaag acccaacggc gaaaactctc
     5761 agttctcggt aaaaaaacgc ttgtcggttc tgcgatacgt aaaatggctt ctaactggcc
     5821 actttttttg actggtaatg cgacatataa aagatcctca ttcaaagtag tacttttgcg
     5881 caaagcgcta cctaggttcc caccattcaa tacggctttg atttcgggac gggagtttcg
     5941 ctgttcattc aatgtttcat tgtttgtgtc aaataagatc tttccagtag catccattaa
     6001 agtaatccgt tcgttcgact gatggacgaa ttcttccaaa gcagttttgt tttgcgctgc
     6061 ttggaggttt tcgacatcta attgccggat cagcagttgt gctttttttg tcaggtagct
     6121 ttcttgctgt tccacgatct gctgttgaaa ataatgggaa atcaattgcc agccaccaaa
     6181 aaacaaacta actaaaagaa taagaaagaa gagacgttca taaatttttt tccatttcat
     6241 cgtttgggtt cctgaaactt atagccaaat cctctaatag tcaccaagta ctttgggtgt
     6301 tttggatctc gctcgatttt ttctcgcaaa tgactaacgt gtacatctac gattcggctt
     6361 tgtcctgcga agtcaaaatt ccaaatgcgg tctagcaatg tgtctcggtc gatcacacgg
     6421 tcttttcgtt tcatgaaata aacaagtaat tcaaattctt tcggtgttag ttcaatcaga
     6481 tggtcgtcta cggtcacttg ataattggtc aaatcagcag tgatttgtcc aatcgataga
     6541 tattcaggct cagcttcatc ttttgattgc ttacgaggtt caattcgtct gaatattgct
     6601 ttcatacggg ctaatacttc gcgaggacta aatggtttgg tcaaatagtc gtcagcacct
     6661 atttctaggc caatgatccg atccacttgg tcatctttag ccgtcagcat caaaatcggt
     6721 gtttcatttt tttcttgacg cagccgctga gtgatctcca tgccatccat cgttggaagc
     6781 atcacatcta aaatgatgaa atcaaatgat tgttctaatg ctaattctaa tccttcgcct
     6841 ccatctgtgg cactggttac cttgtagcct tctttttcca aattgaacgt caagagcgtt
     6901 acaatagaag gttcatcatc aacaactagt atttttttca ttcaaatctc ctttaaatag
     6961 gtttcattct gtttatattt tagcatagaa tcagtacaaa gggctatttt acaaaagaaa
     7021 taaatggtat aataggaagg cactttgctg aatagaaagg aagagcagtc aatgattgga
     7081 atcagtgcat gtttaggcgg tctggcctgt cgctatgatg gacagaaaaa agaagtacca
     7141 gaattgatgg aactagttga aactggagaa gctgtcatgg tctgtccaga agtgatcggc
     7201 ggattaccaa ttcctagaga tcccgctgaa atcattggtg gaaatggatt cgatgtgtgg
     7261 aaagatcaag caaaagtatg gacgacaagc ggcgaagatg taacggaagc gtacaaaaat
     7321 ggcgcgatca aagcctatca aaaattgcag gaaaaacaca ttgatctagt catcatgaag
     7381 gaaaaaagcc cttcatgcgg aacccattcg atttatgacg gaagtttttc cggaataaaa
     7441 aaaaatggtg ccggagtggc tactgcttat tttattcagc aaaaaatgac tgtgctctct
     7501 gatgaagaat ggctgaaaac tagaggtgag cagaatggaa atcgaaaaga ccaatcgaat
     7561 gaacgcgctc tttgaatttt attcgacctt attgacagaa aaacaaatga actacatgga
     7621 attatattat gcagatgatt tttcattagg tgagatcgcg gaagaatacg aagtaagccg
     7681 acaagcagta tatgacaata tcaagcggac aagcaagatc ttggaggatt atgaaaaaaa
     7741 actccatctt ttttctaatt atattgttcg agaacaggta ttggaaaata tgactgcata
     7801 tattacagat aagtacccgg aagataaaaa actacttgaa tatgtacagc aaattcaagc
     7861 aatcgaagaa taaataaaag gaatgaagaa aatatggcat ttgaaagctt aactgaacgt
     7921 ctccagcagg cgatgggaaa aataagaaaa aaaggaaaag tatcagaagc tgacgtaaaa
     7981 gaaatgatgc gggaaatccg ccttgcctta ctagaagccg atgttaactt gcaagtagtc
     8041 aaagatttta ctaagcgcgt acgcgaacgt gcggtagggg cagaagtgct ggaaagttta
     8101 tcacctgcac aacaaatcgt aaaaatcgtt gatgaagaat tgacgatcac acttggttct
     8161 gaaacagcag agttaaataa atcaccaaaa ataccaactg ttatcatgat ggctggtctt
     8221 caaggggcag gtaaaacgac ctttactggt aaattagcca attatttaaa gaaaaatgaa
     8281 aatgctcgtc cgctcctaat cgcaggggac gtatatcgac cagctgcgat cgaccaattg
     8341 aaagtattag gtcaacagct agacgttcct gtatttgata tgggaactga agtcagcccg
     8401 gtagagatcg tccgtcaagg gatggagtta gcaaaagaaa agaaaaacga ctatgtattg
     8461 atcgatacgg caggacgtct gcatatcgat gaaacattga tggatgagtt gaaacaaatc
     8521 aaagaattga cgcaaccaaa tgagattttg cttgttgtcg atgccatgac tggtcaagat
     8581 gccgtcaacg tagctgatag cttcaaccag caattaggta ttacaggggt cgtcatcact
     8641 aaacttgatg gggatactcg aggcggggca gcactatcga tccgctcagt gacaggcgca
     8701 ccaatcaaat tcatcggttc tggtgaaaaa ttgactgact tagaagtatt ccacccagat
     8761 cgtatggcta gccgtatcct tggtatgggg gatatgctga cattgattga aaaagcgcag
     8821 caagactacg acgagaaaaa agcggaagaa cttgcacaga aaatgcggga aaattcattc
     8881 gatttcaatg actttattga acagcttgat caagtgatgg gtatgggccc actggaagat
     8941 ctaatcaaaa tgatcccagg aatgaatcaa gtccctggaa tcgaaaacgt caaggtagat
     9001 ccaaaagatg ttgaacgcaa aaaagcgatg gtttattcta tgacgccagc agaaagagca
     9061 aatcctgatc tgttgaaccc aagccgtcgt cgccgaattg ctgccggttc tggaaacagt
     9121 gttgttgaag tgaatcgaat gatcaaacaa ttcaaggaat caagaaaaat gatgcagcaa
     9181 atgtccaaag gggatatgaa catcccaggt atggaccaaa tgtttggttc aggcgtcaaa
     9241 ggaaaactag gcaaaatggc gatgaatcga atgatcaaga aaaataagaa gaaaaagaaa
     9301 aaacggaaat aagatgaaaa aaacagcttc ggtacagact gaaaatgtct actgccggag
     9361 cttttctatc agcaattttt attctttact aatacaatta ctctaaacga agaggtggca
     9421 cagatgagat gtccgtggag tgaacaaaca gaaagtatgc ggcaatatca tgatactgtc
     9481 tggggtgttc ctgaatatga tgaccaaaag ctgttccgaa aattgatgct tgatattaat
     9541 caagccggat tgagctggca gacgatttta aataaaagtg aagcattcga tgaagcatat
     9601 gatcgattcg atatcaaaaa agtcgcaaat tatggagaaa caaaaatcag tgaactaatg
     9661 gaaaacaaag gaattattcg taaccgaaga aaaatcgaag cagccgtcca aaacgccaaa
     9721 gcagtcttga aaattcaaga agaaatcggc agtttttcag agtatctttg gtcgttttct
     9781 aatggaaaaa tcgttgattc ttcttatcat tcacaagaag aagtcccaac aacaagtcct
     9841 ctttcagatg aattagcaaa agatctaaag aaaagaggat ttaaatttat cggaagcaca
     9901 acaatctatg cttttttaga agctgtcggg atcatcaatg atcaccttga cagttgtttc
     9961 cgcaaagaag aggtcgtacg tatcggcaga aagggcgaat aaagcatgcg aaaaatcata
    10021 ttttatggtg ctataagttt agatggctat ttggcaacga aaacggatga tcttcaatgg
    10081 ctttttgaca ctccaacagg taagcaaact acttatgaag ctttttatga aacaatcgat
    10141 acgaccatca tgggcagaaa aacttatcag gaagcaaaaa aatatttgga gaccgaagca
    10201 atttatccag agaaaaagaa tttcgttttt tccacccacg cacaattaca attgccagat
    10261 gctgaggtcg taaacgaaga tcctgttgct tttctaaaaa atctacaaat gacagaagga
    10321 aaagatatct gggttgtggg tggcggtcga ttgatcaaac cgctattgga acatcaaatg
    10381 attgatgaat ggtatatcca gattacccct gtattattag gggacgggat tcctttattc
    10441 caaaaaggaa catatgaagc gcgttttgaa atgctagaca cgacacgatt cggtgaattt
    10501 atcgaattgc attatgtacg aaagtagaag taaataaaat aaaaaaggca actatatgca
    10561 gaaatgtcct gtacatagtt gcctttttta ttaccgttat gctttttact ctgttaattt
    10621 gttagaaaaa tctagatacg catctaaaat cgtttggaag aaacttaatg ttccttcaac
    10681 gatattacca ttttcatcaa ttagattcgc aacgtttccg atatatgctt ccggttgctg
    10741 caaggttggc acattcaaaa agacaagtga ttggcgtaga tggtggtttg cgccaaagcc
    10801 gccgatccca cctggtgatg cagtaacgac taaacctggt ttatgatccc aaacactgtg
    10861 tccataaggt cttgagccta catctaaagc atttttcaat actgctggca cagaacggtt
    10921 gtattcagga gtaacgaaaa cgacaccgtc tagtcccctc acttcctcac gaaaacgagt
    10981 ccattcagca ggagcctgtt ctggagtttc gagatcctca ttgtaaaatg gcagatcatc
    11041 gatttttaca aatacacttt cgtacccttc aggaagcaat ttcgcaaaag cttctgctac
    11101 ttttttgttg taagaatctt ttcttaaact accaataaaa aatccaattt tttttgtcat
    11161 acgatttttc ctccttcaaa ctatctataa taatcttaca aaagataagt aactggagca
    11221 aataaaaaca cttactgaca aaagctacat agaagataga ttacttattt ttaacaaaaa
    11281 agaagtctaa aatcttctat tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa
    11341 aaagctttac agggtaaaaa aaaactgtta cactacatct tgtgaataaa acaatggagg
    11401 tggaaataaa taatggcagt taaaatccgt ttaaaacgta tgggttctaa aaagagtccg
    11461 ttttaccgta tcgtcgtagc tgattcacgt tctcctcgtg atggacgttt catcgaaact
    11521 gtaggtactt acaatccttt gaaagaccct gcagaagtag ttttaaaaga agacttagtt
    11581 cttgactggt tatcaaaagg tgcacaacct tctgacactg tacgtaacat cctttcaaaa
    11641 gaaggcgtta tgcaaaaaca ccacgaagct aaattctcaa agaaataagg tgaccggata
    11701 tgaaagattt aagcgactta gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc
    11761 aagtcaagtt agacgtcgta gagtcgaaag acttttacga gtacaatcta acagtggctc
    11821 ctgaagatat tggccgtatc attggaaaac aagggcgtgt tgctaaagca atccgcacaa
    11881 tcgtttacgg tgttcggatc aatgcaccga aaaaagtgcg tttgaatatc atcgatgata
    11941 aggaaaagta aataaacgtg ctgtactcga attttcgagt gcagcttttt tgtttttttt
    12001 attaattgaa gaaatgatta tttggcaaaa caagcaagaa agcgtatcct tataggagga
    12061 gggagtgaac agccaatgag aaagaaaatg ttatttattc catttgctct attgttaagc
    12121 gcttgtagtt cggttactca agaatcagac aatacacatc tatcaagcag tatatctgaa
    12181 actgttacca gtccagaaaa aagtagtacc aaaacggctt ccaccactga acaaacaatg
    12241 gctacctcaa ataatgagaa aaagactgct ttagaccagt tgaaagaaca acagccaaat
    12301 gttcccatgc ctctagatgt accagtctct tcaggctatc tcaatatcgc agcgacacat
    12361 acaaagcaag gttattctat tttatattac agaacagatc gtcccctcgg gttgaatgct
    12421 gacgaattga atcaagaaac gcctattgca acctatctat atcaatatgg gtttgcttct
    12481 agtcaagaaa caatccaagt tttgcagcca tttgagatcg acacaaatgg tcagcaagtg
    12541 gacttaggtt ctcgaatcac agggtatcag caaggtgcag caggttcaag ttttcttgaa
    12601 tggcaagaag gaaactggcg tattcgaatc cgtgggaata atatagaagg ccaagatccc
    12661 ttactattag ctaaagaaat cgtagcttat ttggaagaaa acagtctacc agcacctgaa
    12721 caatttggta aaattactgt tgatatgggt gatacgacga atcgagccgt agaagtaagc
    12781 tggcaagaac cgaaaaatgc ctatacgatc actcatcaag atcctatgtc tgcgttgaag
    12841 atggcagttt ctatgaagag gttgtgaaat cagcgcgctg atctgagccc atcatttaac
    12901 tccaagtcac aggaagtaat caaaaatagc acgccgcatt tttgcataat tttggcttaa
    12961 taccttaaaa gaaaactaga attgcctctt cacacatgct aaaataaaac agacaaaaaa
    13021 gaaatgggga tataagttga ctgaatactt gaatgtagga aaaatcgtaa acacacaagg
    13081 tatcaaaggc gaagtccgtg ttatctcaac aacggatttc ccagaagaac gttacaaaaa
    13141 aggaacggtg ctaacactat tccaagacgg aaaagcacct gtggaattaa cagtcaaaag
    13201 tcatcgcaaa cataaaaatt ttgacttatt gagttttgaa ggacatcctt ctatcaatga
    13261 tgtggaaaaa tatcgggatg gcatattaaa agtgtcaaaa gacaactctg tagatctagc
    13321 tgaaaatgaa ttctattacc atgagatcat cggtctgcat gtattagaag atggaactga
    13381 gttaggtaaa gtaaaagaaa tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg
    13441 tccgaaaaaa gctgatatat tgcttccata tatcgcctct gtcgtcaaag aagtcgattt
    13501 agaagctgga gtggtccgtg tagaaattcc agaaggactg attgacgatg aagattgatg
    13561 tattgacttt atttccaaga atgtttgaag gtcctatggg ggaatccatc atcggtaagg
    13621 ctgtagataa aggattatta gatatcaata tctctaactt ccgcgattat tcagataaca
    13681 aacatcagac agtagatgat tatccatacg gcggtggagc aggtatgctg ctcaaagtcc
    13741 agcccatcta tgataacatc caagccattg aaaaagctgc accggatgtc aaaaaaagag
    13801 taattcttct tgacccagct ggtaaacgat tcgatcagaa aatggcagaa gaattttcac
    13861 aagaagaaca cttagtattc atttgtggtc attatgaggg atatgatgaa cgtatccgca
    13921 cattagtgac agatgaagtt tccttaggag attatgtcct tactggggga gaattaggtg
    13981 cgatggtcat gatcgatgca acagttcggc ttttgccaga tgtgttaggg aatcagactt
    14041 cagctcaaac ggattcttat tcaaccggtt tattggaaca tccccaatat actcgcccgg
    14101 cagaatataa agggatgaaa gtaccagaag tattgacaaa tggaaatcat aaattgattg
    14161 aagaatggca attaaaagaa tcactaagaa ggacctatca acgtcggcct gatcttttgg
    14221 aaacacttga atggacacct caaatgacga aatttttaga agaaatcaag aaagaagaac
    14281 aagaaaaaac agcagatgaa gccaagtgac tttttctaaa atcttcttta cagtaggttg
    14341 ataatatgtt agtattttat ggtgagtgca aaagcactta actattacga tattccgctg
    14401 tgagaaaagc tcataagaat atttggaata aggagaagaa aaccatgaat ccattaatcg
    14461 aagaattaac aaaagaacaa ttacgttctg acatcccagc gttccgccct ggtgacactg
    14521 tgcgtgttca cgcaaaagtt gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg
    14581 ttgttatcaa acgccgcggt gctggaatca gcgaaactta tacagtacgt aaagtttcta
    14641 acggagtggg cgttgaacgt acattcccat tgcatacacc acgtgttgca aaaatcgaag
    14701 tagttcgcta cggtaaagta cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa
    14761 aagctgctcg tatcaaagaa atccgtcgtt aatcatcgtt atcagactga gaaagaaccc
    14821 ttggtattca agggttcttt ttttgttctc tgttttttta tattaacgat ttctatttgg
    14881 gacatttttg attaataaaa aggggcaaaa aaggggcaac aagttacagt ttttctatat
    14941 cttctttcaa tttttctttt actccctttg tcacatgcaa ataaatcttt tcagtgatat
    15001 cactattttc gtgcccaacg cgatcctgaa tagcatacag aggagttcct agttccgcta
    15061 attttgaaat atgggtatgt ctaaaaatat gtgaactaag ttttttatca atcttcatgt
    15121 cagctttatg atttctcaaa taggtgttaa ttgctgttag ttggaaagga gttcctttcg
    15181 ttgtttgaaa tagaaattga ccattcggat ttaattctag aagctcattg taaatagcta
    15241 tcgctttttt tggtaaatca atttctcgca ttccagcagc agtttttgta gaatcagatt
    15301 ttttcatatc agctattgaa cgttctctat acatcatcgt cccatttata actactgatg
    15361 cattattatt ggtaatgtgt acatcgtctt tacttaatgc gattgcttct ccaggcctca
    15421 ttccagtcaa atatagccac tggaaaagga gagaatatct tttattgtgt gaagttgtga
    15481 aatttactag tcttttatat tcatcatctt ctaaaaactt atctttaatt tttatcgttt
    15541 ttgactctcg tttataatca ataactactt cgttgatagg atttttttct acatagcctt
    15601 ttttcatagc gtatgaaaaa agaagattca atttggattt aattacactg acgtacttat
    15661 ttgacaagtc atctttatat atcatatctt caaaaatatt atttaaatct actgtattaa
    15721 taccagaaac gatgtaagtc tcaggtatct ttttctttat agtgtttaag atattattcg
    15781 taggataata tgtagactcc ttaacttgtc ttttgtaaat aactaaccat tcttcgacaa
    15841 gctcatgaaa tgttagatca ggcttctgaa gtgttttttc gtttaatttt atatcaattt
    15901 ttttatttaa ctctagcaat gccactttct gagtttctcg agatttattt ttataagtaa
    15961 tgctcacttt ttttcttttt ctagtttttg gatcaatata tcgctcatta tatttatata
    16021 ctttttttcc gtttttatca gttttggttt caatccacat tgttttcatc tcctatttgt
    16081 tgctataata ggaatggata agtaagccaa ttatagcagg tttatttttc atcacgtcca
    16141 caaactttgg cgagggaggg ggcgtgtttt tttgtttagt agctaccttt ccatgaagta
    16201 tctgcgaaga acacttcaaa tgttgttcca tcatttttca cttcaaaata tgctgttcct
    16261 tgtgcggatt tacccggttg gatggtttcc gaaaagtaat ctctactagc taaatcagat
    16321 ttaatatctg atgaatcata aaattctaaa taacttgaac ttgcatcaaa aggtgtagtc
    16381 cctgtgtttt ctacaagaaa atctaccttt gcgtaaaata ggccttctgg tttatagaaa
    16441 tcatcaccgt aatcttttga tacagactgg acagttacgt taatagagtt accattttca
    16501 gaagtaaaag gaactgcttc tcctatacta tgtgcaactg atgccgtctg gggttctgaa
    16561 gacgaagttg tagttgtagt tgtagtagag cttgaatctt tggattttcc atctttatct
    16621 aagaaagttc gttgattata atatacaacc tgttcagttt ttggactaac ccaaattaac
    16681 attgtttcat catcagaatc agttgaataa gtatattgga gcatctctaa tttttttata
    16741 tcttttgcac tatttccatg ttcaattaat tcagagtgct ctttataata atctccttgt
    16801 gcatcctttg aaatagatac aattaattca tcccgtgtga tagcattgtc taattctttg
    16861 taaacaaaat catttgtcca tttacgtaac ggtgaaccaa gtgtctgata aacttgagtt
    16921 aaatcatcac caacttttat tttatgaacg tctgatgaag ttagtttttt tgtttcatat
    16981 tcagatgttg atgaaacagt attttcttta gtgctagcag aattaggact agtggagcat
    17041 ccgcttaata ccaagcctaa aaaaagcaac ccaaaaacaa tttttttcat ttttaattcc
    17101 tcacttctat gatatgattt ttttgtagga tcttagaaat aaggttttta gtccgtgttg
    17161 cagcacggac tttttttaca ttatataaga aagcgataag cgctttctgg aagtccgtaa
    17221 agattcttta attcctcaat tcgtttagga tattgatcat tgtcttcttt gtatagagaa
    17281 acaatgagat tagcagcaaa gcaattagct tcgctttcag atttgcttct agatgttctt
    17341 gttgatacat agtaactgga taagccacga tgaaaaatag cgtgacctaa ttcgtgagcg
    17401 caaatgtaga atctttcctc agagtctctc agttcatcat ttaagaagat tattgcacga
    17461 cctctaattt cttgaaactg tcctttggga ttctcgataa aaggaacgta ttgaatttta
    17521 atgcccatct tttcacaaat ataaaaagga ttagcggact ggtatttccg cttcaactcc
    17581 tcgactaaat taatcgtatc catctccata agctcacatc tttttgcctt tttctttgtc
    17641 ttctttcaca atatcccaga aggttccaat aaggatatct tttacgcgtt ggacctgttc
    17701 aggcgtcagt gtttctccgc cataagacat attgacattt gaatctagta atttatcaag
    17761 ttcaactact tcatcttttg ttgcccagtc aggaacttgg tttctaccga gtaaataatc
    17821 agtagttaca ttaaaataat ctgctacaag ttgtagtctt ttagtactag gagttctatt
    17881 tttccattga taaatcgtgt ttttaggtat atttaattct tcttccaatt gagttatact
    17941 tatgcctctt ttatgagcta attcctttat tctatctagt aaattcattt tcgcacctca
    18001 caagctacga aaacactaat aaaaaaatta gttaaaggtg ttgacaacta ataaaagtgt
    18061 tagtatactg ttttcgtaag ctaaaatatt agctaaaaag acttgataac taataaacac
    18121 ttcacggtcg gcaaactctg aaatgtaaat tactaggcat ttctgtgtct t
//
LOCUS       DADVXB010000052        18060 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.053, whole genome shotgun sequence.
ACCESSION   DADVXB010000052 DADVXB010000000
VERSION     DADVXB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.053"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..335
                     /locus_tag="KB902_001371"
     CDS             <1..335
                     /locus_tag="KB902_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6808208.1"
                     /translation="KLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKK
                     TGGLRYAPALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKRED
                     FNEAQKIR"
     gene            351..1112
                     /locus_tag="KB902_001372"
     CDS             351..1112
                     /locus_tag="KB902_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6808209.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            1243..2577
                     /locus_tag="KB902_001373"
     CDS             1243..2577
                     /locus_tag="KB902_001373"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBB6808210.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            2884..3369
                     /locus_tag="KB902_001374"
     CDS             2884..3369
                     /locus_tag="KB902_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBB6808211.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            3362..4045
                     /locus_tag="KB902_001375"
     CDS             3362..4045
                     /locus_tag="KB902_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBB6808212.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSILNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            4171..6816
                     /gene="polA"
                     /locus_tag="KB902_001376"
     CDS             4171..6816
                     /gene="polA"
                     /locus_tag="KB902_001376"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBB6808213.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            6861..7697
                     /gene="mutM"
                     /locus_tag="KB902_001377"
     CDS             6861..7697
                     /gene="mutM"
                     /locus_tag="KB902_001377"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBB6808214.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            7661..8290
                     /locus_tag="KB902_001378"
     CDS             7661..8290
                     /locus_tag="KB902_001378"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBB6808215.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            8342..8674
                     /locus_tag="KB902_001379"
     CDS             8342..8674
                     /locus_tag="KB902_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6808216.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            8986..9477
                     /gene="nrdR"
                     /locus_tag="KB902_001380"
     CDS             8986..9477
                     /gene="nrdR"
                     /locus_tag="KB902_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBB6808217.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            9500..10873
                     /locus_tag="KB902_001381"
     CDS             9500..10873
                     /locus_tag="KB902_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6808218.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            10873..11799
                     /gene="dnaI"
                     /locus_tag="KB902_001382"
     CDS             10873..11799
                     /gene="dnaI"
                     /locus_tag="KB902_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBB6808219.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            11928..12368
                     /locus_tag="KB902_001383"
     CDS             11928..12368
                     /locus_tag="KB902_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6808220.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            12512..13213
                     /locus_tag="KB902_001384"
     CDS             12512..13213
                     /locus_tag="KB902_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBB6808221.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            13210..14331
                     /locus_tag="KB902_001385"
     CDS             13210..14331
                     /locus_tag="KB902_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBB6808222.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            14346..15578
                     /gene="pepT"
                     /locus_tag="KB902_001386"
     CDS             14346..15578
                     /gene="pepT"
                     /locus_tag="KB902_001386"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBB6808223.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            15710..16618
                     /locus_tag="KB902_001387"
     CDS             15710..16618
                     /locus_tag="KB902_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBB6808224.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            16653..16925
                     /locus_tag="KB902_001388"
     CDS             16653..16925
                     /locus_tag="KB902_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBB6808225.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            16936..17982
                     /locus_tag="KB902_001389"
     CDS             16936..17982
                     /locus_tag="KB902_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBB6808226.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         6100 a         3136 c         3946 g         4878 t
ORIGIN      
        1 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
       61 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
      121 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
      181 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
      241 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
      301 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
      361 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
      421 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
      481 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
      541 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
      601 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
      661 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
      721 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
      781 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
      841 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
      901 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
      961 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
     1021 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
     1081 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
     1141 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
     1201 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
     1261 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
     1321 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
     1381 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
     1441 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
     1501 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
     1561 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
     1621 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
     1681 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
     1741 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
     1801 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
     1861 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
     1921 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
     1981 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
     2041 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
     2101 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
     2161 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
     2221 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
     2281 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
     2341 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
     2401 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
     2461 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
     2521 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
     2581 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
     2641 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
     2701 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
     2761 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
     2821 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
     2881 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
     2941 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
     3001 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
     3061 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
     3121 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
     3181 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
     3241 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
     3301 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
     3361 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
     3421 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
     3481 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
     3541 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
     3601 aatcggtgga tttattgcct actctatttt gaatggcata acattagcgg ttactcttgc
     3661 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
     3721 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
     3781 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
     3841 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
     3901 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
     3961 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
     4021 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
     4081 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
     4141 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
     4201 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
     4261 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
     4321 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
     4381 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
     4441 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
     4501 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
     4561 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
     4621 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
     4681 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
     4741 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
     4801 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
     4861 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
     4921 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
     4981 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
     5041 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
     5101 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
     5161 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
     5221 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
     5281 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
     5341 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
     5401 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
     5461 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
     5521 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
     5581 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
     5641 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
     5701 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
     5761 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
     5821 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
     5881 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
     5941 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
     6001 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
     6061 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
     6121 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
     6181 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
     6241 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
     6301 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
     6361 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
     6421 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
     6481 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
     6541 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
     6601 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
     6661 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
     6721 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
     6781 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
     6841 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
     6901 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
     6961 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
     7021 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
     7081 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
     7141 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
     7201 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
     7261 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
     7321 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
     7381 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
     7441 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
     7501 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
     7561 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
     7621 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
     7681 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
     7741 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
     7801 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
     7861 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
     7921 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
     7981 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
     8041 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
     8101 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
     8161 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
     8221 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
     8281 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
     8341 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
     8401 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
     8461 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
     8521 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
     8581 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
     8641 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
     8701 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
     8761 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
     8821 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
     8881 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
     8941 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
     9001 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
     9061 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
     9121 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
     9181 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
     9241 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
     9301 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
     9361 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
     9421 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
     9481 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
     9541 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
     9601 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
     9661 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
     9721 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
     9781 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
     9841 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
     9901 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
     9961 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    10021 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    10081 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    10141 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    10201 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    10261 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    10321 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    10381 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    10441 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    10501 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    10561 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    10621 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    10681 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    10741 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    10801 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    10861 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    10921 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    10981 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    11041 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    11101 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    11161 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    11221 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    11281 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    11341 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    11401 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    11461 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    11521 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    11581 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    11641 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    11701 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    11761 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    11821 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    11881 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    11941 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    12001 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    12061 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    12121 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    12181 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    12241 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    12301 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    12361 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    12421 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    12481 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    12541 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    12601 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    12661 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    12721 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    12781 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    12841 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    12901 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    12961 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    13021 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    13081 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    13141 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    13201 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    13261 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    13321 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    13381 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    13441 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    13501 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    13561 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    13621 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    13681 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    13741 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    13801 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    13861 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    13921 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    13981 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    14041 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    14101 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    14161 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    14221 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    14281 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    14341 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    14401 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    14461 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    14521 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    14581 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    14641 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    14701 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    14761 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    14821 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    14881 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    14941 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    15001 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    15061 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    15121 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    15181 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    15241 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    15301 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    15361 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    15421 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    15481 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    15541 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    15601 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    15661 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    15721 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    15781 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    15841 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    15901 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    15961 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    16021 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    16081 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    16141 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    16201 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    16261 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    16321 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    16381 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    16441 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    16501 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    16561 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    16621 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    16681 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    16741 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    16801 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    16861 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    16921 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    16981 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    17041 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    17101 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    17161 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    17221 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    17281 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    17341 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    17401 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    17461 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    17521 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    17581 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    17641 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    17701 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    17761 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    17821 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    17881 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    17941 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    18001 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
//
LOCUS       DADVXB010000053        17799 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.054, whole genome shotgun sequence.
ACCESSION   DADVXB010000053 DADVXB010000000
VERSION     DADVXB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.054"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1336)
                     /locus_tag="KB902_001390"
     CDS             complement(<1..1336)
                     /locus_tag="KB902_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808227.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTN"
     gene            complement(1634..2569)
                     /gene="murB"
                     /locus_tag="KB902_001391"
     CDS             complement(1634..2569)
                     /gene="murB"
                     /locus_tag="KB902_001391"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBB6808228.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2642..3562)
                     /locus_tag="KB902_001392"
     CDS             complement(2642..3562)
                     /locus_tag="KB902_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6808229.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3675..4427
                     /gene="xth"
                     /locus_tag="KB902_001393"
     CDS             3675..4427
                     /gene="xth"
                     /locus_tag="KB902_001393"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBB6808230.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5291..5824
                     /locus_tag="KB902_001394"
     CDS             5291..5824
                     /locus_tag="KB902_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBB6808231.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6314..6838)
                     /locus_tag="KB902_001395"
     CDS             complement(6314..6838)
                     /locus_tag="KB902_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808232.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(6831..7304)
                     /gene="tsaE"
                     /locus_tag="KB902_001396"
     CDS             complement(6831..7304)
                     /gene="tsaE"
                     /locus_tag="KB902_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBB6808233.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7427..8407)
                     /gene="pta"
                     /locus_tag="KB902_001397"
     CDS             complement(7427..8407)
                     /gene="pta"
                     /locus_tag="KB902_001397"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBB6808234.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8560..9240)
                     /locus_tag="KB902_001398"
     CDS             complement(8560..9240)
                     /locus_tag="KB902_001398"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6808235.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9366..10235
                     /locus_tag="KB902_001399"
     CDS             9366..10235
                     /locus_tag="KB902_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6808236.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10261..10776
                     /locus_tag="KB902_001400"
     CDS             10261..10776
                     /locus_tag="KB902_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808237.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(10823..11416)
                     /locus_tag="KB902_001401"
     CDS             complement(10823..11416)
                     /locus_tag="KB902_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808238.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11441..11620)
                     /locus_tag="KB902_001402"
     CDS             complement(11441..11620)
                     /locus_tag="KB902_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808239.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11697..12206)
                     /locus_tag="KB902_001403"
     CDS             complement(11697..12206)
                     /locus_tag="KB902_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808240.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12302..12682)
                     /locus_tag="KB902_001404"
     CDS             complement(12302..12682)
                     /locus_tag="KB902_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6808241.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13012..13761
                     /locus_tag="KB902_001405"
     CDS             13012..13761
                     /locus_tag="KB902_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBB6808242.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(13945..15222)
                     /locus_tag="KB902_001406"
     CDS             complement(13945..15222)
                     /locus_tag="KB902_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808243.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15301..15945)
                     /gene="pcp"
                     /locus_tag="KB902_001407"
     CDS             complement(15301..15945)
                     /gene="pcp"
                     /locus_tag="KB902_001407"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6808244.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16144..17088)
                     /locus_tag="KB902_001408"
     CDS             complement(16144..17088)
                     /locus_tag="KB902_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6808245.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17090..17776)
                     /locus_tag="KB902_001409"
     CDS             complement(17090..17776)
                     /locus_tag="KB902_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6808246.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         5166 a         3651 c         3092 g         5890 t
ORIGIN      
        1 tattcgtacg agaagtgatt cgactctcaa tcacaatatt gtaattttta aatcctttca
       61 cttgagaaat aatgtaatcg gtataagcag atccttgcga aaaatcaata cagacatgaa
      121 tcggtgcttc aaaatatgat accggacaaa taccgaccaa taaaaagaga taatcataaa
      181 ataagcgaat catgaaacgt tcatcttttc ccaagaaata gcgtttattc tcttgtatga
      241 ccttttggat tgctgtactg aatattggat acgtctcgaa gaaaaactgt agctgctttt
      301 tagacgtaaa gctagtcatc tcaaagtcga atatccaatt ttttcgattg acatgcatca
      361 tacccatacg aagttctttt cgtatatata gtctttcttc ttcagagatt tcaatcgaaa
      421 atggtaattg atcaatcaat tccactgaca ttttttgact aatcatgtgg atatcatgaa
      481 aatgagcttc cgcaagtcca aatgcgccat ctaattcaaa ttcttcttcc gtgatcaaaa
      541 acaacatgat ataagaaatc tcatcaatga tctgctcttt agggatatga agaaaagaaa
      601 tatgtgataa atccttgatg atcttcattc cttctgagct cttaaagtat tcatctgaaa
      661 agaaacgttt tccgattggt tgattcccat aggccctcaa caaactaata gtggttagca
      721 aattgaattt gattcgtttt gttgcagaca gttttaaatt gaacagatat tcaaaatatt
      781 gcacgatact ctttgcttca ttcatgacgc tttctctaaa tggcatagaa aaaccattaa
      841 agaccccgaa atatacccca aataatacgt tccgtatgtt tatttcttcc ccaactaata
      901 tgtttttctt taactttatt tgatgctgtt caagaaaaga gactaattct cttcttttta
      961 cataggctct tgatatgctt aaaaaatgat tctctgcaaa tttttcgatc gttacttttg
     1021 aatccacgat ctccgttaac agtcgagcaa tttttgatcg ttgaaagtag attcttctta
     1081 aatttttgat atccgtcaaa ttcagacgtt cgacatggat ctctgcttct tctgaaattt
     1141 ggatctctgg ctttgttttg aattcagtaa attctttatt taattctatg atataatttc
     1201 ttgttttaaa tttagacaaa cctaatgttt catataactt aggcagcact acataattct
     1261 ttttctcaaa ttctaaatat ctagctagca gcagtttttc tctatcttcc tcttctataa
     1321 ggtaatccaa cttcatatcc tacacctcaa aaaatgcctc ataccaatta cttgatatgc
     1381 agatgaaagt tcatcttttc acctatactg attttatgat ggattatgct tgttttttca
     1441 tcagttattc tcatttttta tctttttttt gagaatattg caaaaaatgg aaaaatttat
     1501 gaggaaatat tctatatttt ttgttttatt gtgttaaaat gtacaagatt tgcgccattt
     1561 gcgtaaacaa ccacaaaaaa gagcaggacg gccaccgtcc tgctctttta cttattttaa
     1621 gttccattac ttattaattg gctaaacttc tgcttgtttc tgatattgct tgtttttctc
     1681 caatgatccg cacttctgtt tctaaagaca catcaaattt ttctttgatt acttcttgga
     1741 tgtgcgcaat caattcaata taatctgtcg ctgtcgcatg atcgatattg acgatgaatc
     1801 cagcatgttt ttcagagact tgtgcaccgc cccatttcag gccttgcaat cctgcttgtt
     1861 ggatcagctg acctgtatag tgtcctactg ggcgcttaaa gacacttccg catgaagggt
     1921 attctaatgg ctgttttgat tgacgcaatt cggtcaactc atccattctt gctttgattg
     1981 cttcataatc ccctgtttgc aaactgaatc gagcttccaa tacgatagca cgtaattctt
     2041 ggactttact gtgacgataa gaaaatacca tttcgtcttt tgtcaaagtt ttcaatgttc
     2101 catcttcaag caaaagatcc acttcagcaa aaacatcttt gatctctccg ccatacgcac
     2161 ctgcattcat ataaaccgct ccaccgacac ttcccgggat gccgcaagca aattcaaatc
     2221 cagtcaatga ttctgccaaa gctgcataag tcgtatcaat cagtgaggca cctgcttccg
     2281 caatgaccat cgttcctttg acatgaatct gtttcatttc agtcagcatg atgactacac
     2341 cgcgaatccc gccatcttga acgatcagat tgcttgcatt tcctaatacc atccaaggta
     2401 tatcatggat tcggcaataa tcgatgattt gctttacttc ttcttgtttt ttcgggaatg
     2461 caaggacatc agctggtcca cctgttttcg taaacgtata gttcatcaat ggttcatcaa
     2521 acaatatagt aatcgtggct aagctttcaa ctatttcttc tttattcact gaggattttc
     2581 ctttcttttc tcaaacgtcc tcattattct atcacgctta atacaatctt gccagtcttg
     2641 ttcaaagttg atgacggtag tgatctttaa gcacttcctc acataattca tgacttctta
     2701 caacttcttt ttgtttaagc aattctgttt ccgatttacc taaacggatc tgagaaaaga
     2761 aggcctctac cattggctca aacccgcgtt tgactagcgt gtttgtccag tcgccaaatt
     2821 ctttcacttt ttttccatca gcatcttgaa tgacaagctg ggtcagatcg tttacttcat
     2881 aagtaccatt tttacttgtt acttgatatt tttctatatt agcgccactt gctaaatcca
     2941 tcgttaaaat agccgtttga ttttgtgttt ctaattgtaa aatggcatat tccaaaaatt
     3001 cctttgtttc tcttatctgg tattttgttc tcaaaatggg ttcatctaat aaatacacag
     3061 ctgtatcaat aagatgtaaa aacaaatcat aaaggacgaa ctctgtcgtt tcttttgccg
     3121 ctattcgatt tttttgcagg tggatcaacc gcttatctgg gatacgtttc aattcttcta
     3181 ccataggagc aaagcgccgg ttgaaaccga tcatcaaaat tatttggttc ttatcagcta
     3241 attcttgcaa ttcacgaact tcatttagat ggacactcag tggtttgtca atataaacat
     3301 ggataccatt ttctagacat tttttggcta attcataatg tacttttgtt gctgcgtgga
     3361 tcatacatgc ttcgattttt tcttctaaaa gctcatcgat cgtttcatat agatgttgga
     3421 acccgtactc tttttgaatt ctttcttttg tttctttatt tcttgttgca aaataaaaat
     3481 caagtgttcc ttgttttttc gcataagttg gtaaatatgc tttttctgcg atattcccta
     3541 caccgattac accaatcttc atctactttc ctcctggatc atttagttac tttcatctta
     3601 caccattttt tactaaaatg aggtacaata gtatcgcaaa ggtaaggaaa ttaattcgaa
     3661 ggagtgtgct tttattgaaa tttatctctt ggaacgtaaa cgggcttcgt gccatcgtaa
     3721 ataaaaattt tttagaagtt tttcatgagt tagacgccga ttttttctgt ctgcaggaaa
     3781 cgaaactcca agcaggacaa attgatttag atcttccagg ttattatcaa tattggaatt
     3841 acgcggaacg aaaaggctat tccggcacag cgatttttgc taaaaaacca gcattgaatg
     3901 ccacttacgg aatgggtatc gatatccatg atacagaagg ccgtctgatt actttggaat
     3961 attccgattt ctttcttgta acctgttaca cgccaaattc tcaaagcgaa ttaaaacgtt
     4021 tagattaccg attagaatgg gaagaagcct tttataatta tttggaaaat ctaaaaaaac
     4081 aaaaaccagt catcgtgtgt ggggatctaa atgtcgctca tcaaaagatt gatttgaaaa
     4141 actggaaaac gaatcaaaaa aatgctggat tcactccaga agaaagagcg gctctttctc
     4201 gactgttgga taacgggttt atcgatacat tccgttattt ttatccaacc caggaaggtg
     4261 tctactcttg gtggaactac cgattcaatt caaggaaaaa caatgctggt tggcggatcg
     4321 attacttttt gacgagcaaa gatttagagc caggactagc tgatgcaaag atccatacgg
     4381 acattatggg cagtgatcat tgtccagtag aattagattt gaaataaaga ggttgtgaaa
     4441 aagtcgttta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc acattttgca
     4501 taaatttggc ataataccga gaaactggct tttgaacact gtttatcgag agattgtgaa
     4561 aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catatttttc
     4621 gtttggttgg gcttattacc gcagatacaa gcttttgaac accgtttatt aagaggttgt
     4681 gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
     4741 ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt attaagaggt
     4801 tgtgaaaaag ctgcactgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4861 tttttcgttt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttattgaga
     4921 agttgtgaaa tcagcgtcct gacctgagta ttagagaaac aaatggcaaa atagttcctc
     4981 atattttgct attttttgag ctaataccga gggtcagctg attgaacacc gtttagtgga
     5041 gaagttgtga aaaagtcgcc tactttcgag tcgtaagaaa tttttttgaa aatggttcct
     5101 cacaactttg cataaatttg acttaatacc gagaagtcat gatccccatc taactccaaa
     5161 tcacaaggaa tgagttcaaa aactagcttt tctcaacaaa tattacataa aaaattctat
     5221 gttttttgtt aaatttattt gcttttttca aaagtatgtt acagtaattt cccaaggagg
     5281 ttttacagaa atgaattttg ttgccatgga ttttgaaact gccaatcatc agccttatag
     5341 tgcttgttct cttgcgctag tcatggtaaa aaatagccag atcgttgatg aattctatac
     5401 attgatacag cctgagactc cttttttctg gcgaaatgtc caaattcacg gaatccatca
     5461 agaagacgta cgcaatgcgc cgaaattccc agaagtctgg caaactatcc aaccatattt
     5521 tcaaaaaaat cgtttagtcg ttgcacataa tgctgctttt gatacaaagg tcttagcggg
     5581 atgcttagat tattatcatc ttgaacagcc taattatctt tctttatgta cagtgaaaag
     5641 tagccgtcgc ctgtttcctg aatttccaaa tcatcgattg aacactgtgt gcgaaaattt
     5701 gaacatccaa ttagatcatc accatgatgc attggaagat agtcgtgcat gtgcggaaat
     5761 cctgctttat caagaaaaaa aattcgggac agatccattg aaaaaacttg tgactataaa
     5821 gtaaaagaat acttatgaaa cacacaaaga ggtcgtgagc ctgccgtttc actccgagtc
     5881 acaaggagca atttcaaaaa atagcttctc atgtttatta aatattgtga ctggtgaccg
     5941 aggagctggc aggagaacac cgtttattgg agaggttgtg aaaaagctgt tctgcatcaa
     6001 gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcatttggtt ggacttatta
     6061 ccgcagatgc aagcttttgg acaccgttta ccaagaggtt gtgaaatcag cgttttgacc
     6121 tgagtattag agaaacaaac ggcaaaatag ttcctcatat tttgccgttt tttgagctaa
     6181 taccgaaggt cagctgattg aacaccgttt attcaaaaaa aatggactgc gacacgactt
     6241 ttgtcacagt cccttcgtgt gtttttctgc cttctcaaaa ggatgacagt ttctcactct
     6301 tttcctattt cttctattca atcaaataac tcattttata tacatctaaa aattcaccta
     6361 gatctgttct tgcccctcta ggcatgaccg cttcgatttg gaagcccatt tttcggtaaa
     6421 ggtgtacggc tctttcatta cgaacttgaa cgtcaagctc caatcgaaaa agtacaccca
     6481 tttccttcgc ccaactgatg atttcttcta gcataagagt gcctagtccc attccccaat
     6541 attcctgcag aatactgata ccgacttctc ccacgtgaga caaacgaaat tgactgtctg
     6601 ccttgacaga tgctgttcca ataatcgtcc cttcatagat tgcaagcagc aataaattat
     6661 tattgctttc gtatatataa tccaactctt cttctaaggt ttctggtggt aacaggagtt
     6721 ctgcttcatc caaaactaaa aattctgtct ccttattaac ttgtcccatc atcaaaagaa
     6781 tgtcttttgc atctcctggc actgcttccc gcaagatgat cccaacttct tcactcatga
     6841 ttttcagccc atttttctag aattcgctgt ttgaaggttt cactttgctc cccgtatgag
     6901 attagtttca cataccgctt ttctaaatct gtatcacttt tttctaaaat cagttccaaa
     6961 taatcctccg gcagtgcttc ttctaataga tttccccatt caacaacgga aagcccatca
     7021 ccttcaaaat attcatctaa ccctaaatct gctccgctag ctgctacccg ataaatatcc
     7081 atatgataca acggaatccg accttgacta tattctctaa taatcgtgta tgtcggactt
     7141 ttgatcattt gcgttatccc taatccttgg gcaattcctt tcgtcaacgt tgttttaccc
     7201 gcacctagat caccagtcaa tatcagattg tcacctggca ttgcggaatg accaattgcc
     7261 tctgcgaatt gttctgtcat tgttaatcct gatagttcga tcatttttca tcttctcccg
     7321 ctcttctttc tttttgccag tatatcgcgt aatgaagttt ttttaaagaa aaaatgaact
     7381 agtcaagaac agcagctgct gtttttggct agttcgcgtg tatttgttaa tcaatcaatg
     7441 tttgtgctgc tgtgataatc gataatttat atacatcttc ttcatttgct ccacgagaca
     7501 aatcagaaac cggtttgttc aagccttgta gaattggtcc gattgcttca aagttaccga
     7561 aacgctgagc aattttatag ccgatatttc ctgactgcaa ttctggaaat acaaagactg
     7621 ttgcttgacc agctacttct gaatctggcg ctttcagttg tgcaactgaa ggaacataag
     7681 aagcatcaaa ttgcaattcg ccgtcgatca tgtattgtgg cgctagtttt ttagcgattt
     7741 tagttgcttc aactactttg tctacttctg gcgatttcgc tgagcctttt gtcgagaagc
     7801 tcatcattgc tacttttggt tcgatatcga acaattctgc tgtttttgca gaatctacgg
     7861 cgatttcagc caattcttgc gcagttggat tcacgttgat cgcacaatcc gaaaagacat
     7921 atttttcttg atctcttcca cgtaccatga tcatcgctcc gcttgtccga ctgatgccag
     7981 gctttgtttt gatgatctga agtgctgggc gaacagtgtc gccagtcgaa tggatcgctc
     8041 cagagaccat tccgtctgca atccccatat acgtaagcat cgtaccaaag taattcacat
     8101 cttttaaaat cttttctgct tgttctttgg atgcctttcc atttctacgt tcaacaaaag
     8161 tatccaccat ttcatcccac ttatcgtaat tatcagggct gatgatcgta aagctagatg
     8221 ttttgattcc tctggcatgc gctgcatttc ttatttcttc ttcgttccct actaaaatgg
     8281 gttccacaag ttcttctgct ttcaaccggg cagctgcgcc taaaatacga gcatcagtag
     8341 cttccgggaa aacgattttg atcccacggc gaacaatttt aaatcttaaa ctatcaaaca
     8401 attccacaag atgacctcca gacgttttta tatgtattat catacactat tccagaaaaa
     8461 aagaacagtt tattttatct gtatcagtca aaaatgctgg aaaaattaag tttttcacat
     8521 acaaagcgaa ctgcactata acaggaaagc gctgttttat tacactgttt caggcagttg
     8581 ccaatcaatc ggttcttctc ctaacgcaag gagcgcatca ttcgttttcg agaagggttt
     8641 ggaaccaaaa aagccacgac ttgcagataa cggactggga tgtggagatg ttatgatgat
     8701 atggcgactc ttatcgatca ttttgatttt ttcttgtgcc ggttttcccc acaagataaa
     8761 cacgattggt ttttcccgtt catttaattt ttcaatgatc gtgtctgtta atctttccca
     8821 acctttcccg cgatgagaat acgcttgccc ttcccgaacg gtaagaacgg tgttgagtaa
     8881 aaggactccc tgtttagccc atgacactag atttccatgt tgaacaggtg cgattccaag
     8941 atcatcataa agctctttat agatatttct taacgatggc gggatcttta cgccaggttg
     9001 cacagaaaaa gataagccat gagcttgatt ttctccatga taaggatctt gtcctaaaat
     9061 caccacttta acttcttcat aaggagtcaa ttccaatgct tcatagatat gatacatatc
     9121 tggatggatc ttttgggacg catattcttt ttttaaaaat tctcttagat gcagataata
     9181 atcttttgaa aattctgagg acaaaacttc ttgccaactg ttatgaatga tttctttcaa
     9241 aaactccacc tcctaataaa aagaataact cacattttct tcaatcacaa gggacaatct
     9301 tcaccctcag cacttgatta atatggtaaa ctaggaacaa gaagcagaaa ggaacgataa
     9361 tcattatgat caaattaatt gcatcagata tggacggcac attattagat gcccatatga
     9421 gtgtttctcc tgaaaatgcc gaggcgatac gttttgcaaa tgatgccggt gttgagttca
     9481 tggtcgctac tggtcgaaac tatcaagaag ctcgcgcagc tttagatgag gtaggaatcg
     9541 attgtgcgat gatcactttg aacggggcac aggtatttga taaagaagga aattcattgt
     9601 ttaccgtgtc gattccaaat aatcaagcaa tctctgtttt agatattcta gatgctaacg
     9661 gtatttacta tgaagtagca accaacgatg gtctttattc tgaaaatcaa gcgaaacgaa
     9721 ttgaaagttt tgcttccatg gtggctaccc atttacctca ccttacgtat aaaatggcga
     9781 ttgccatggc ctcagctaag ctggagttat tgcacatcac atacgtggac agtattcgtg
     9841 ctattttgga agaaaagaat ctggaagttt taaaaattat ttgttttcat acagaagggc
     9901 cagctgtatt aggtccagtt ggaaagcaga tttctctttt aggcgatcta gccgttactt
     9961 cctctggtca aaacaatatc gaagtgaacc ataaaaacgc tcaaaaagga attgctgttg
    10021 cccatgtcgc tcacgagcgt gggatttctt tagaagaagt catgacgatt ggcgataact
    10081 tcaatgatgt cagcatgctg caagtagcag gagtcagttt cgcaatggga aatgcagaaa
    10141 tcgaagtaaa agattatgcc aaatatacaa cggacacaaa ccttgaatct ggcgtaggaa
    10201 aagccatatt gcgcgcgatt gcagaagact tgtagtttta tctagaaaag agggatatag
    10261 atgtcagaat ttttcattca ggaaaagcag cttggacgtg caactcggac aattgtcaaa
    10321 aacgaaaaag gacattccct gtttttgatg gttggtcgct ggggaacaaa gggcgatgca
    10381 ttgtctcttt atgccatgaa tggcgatctc gttgctcaca tcaagcagat aagcctgaca
    10441 ttcggtacgc gttttgagct gtataaagag ttcgaaaagg tgggaaccat gcagaaaata
    10501 ttcaattggc ccggtgactt ttattatatt cgtagacttc actggacagt ccaaggtgat
    10561 atctataatc atcaatatca aatccatcat ttcaatcagc aaatcatgaa aatggataaa
    10621 gcaacacttt tttcaggaga ttactatgta ttggatgtct caaatgatga agatgctcca
    10681 gtttgtattt gtattgctgc ggttttagat tactggctct accgtaaaga caaaagtcgc
    10741 gataagcctg tttcttaccg acttaactta agttaaaaag atgtacctga aatgcggaaa
    10801 tacgcatttc aggtacatct ttttagatat tcttttgcat atgatcataa agatgaccac
    10861 tgatcatccg ctgaccgaca actttgaagt catggcgttc gtataatttt ttagcctttg
    10921 gatttttttc atccacactt agaccgatga cggagcgatt agctttcttc gccaatttag
    10981 gtaatgcttc taataatcgc gaaccgatgc cttgtcctct aaaatcttct gatacactga
    11041 tagagtccaa ataccattcg ttgggaaacg tttctttatc aatgaacaaa cgtgtagacg
    11101 catctagctg atatttctct aagataggta ccagtggctg atcgatgatt gattcttctt
    11161 catctgtata accgtaagca actcctgcaa ctttaccgtc tatttcttct acgatacctc
    11221 gtgaataact gtaacgataa tttggatcag tgattgcttc ttctaaaatc tctaaagtct
    11281 tttgttcccc tgtctgcttc aaaaatggca gttccatatc ttttagaatc actaagatca
    11341 atggggcgat ttctggagca tcttcttttc tcgcaaaacg aatcatagtt tcctctcctt
    11401 ttctccattc taacatgcag aaaaagaaat cgcaaaatcg ttattttaaa aaatcttcaa
    11461 tcttttcagt aatgaaataa ccatgagtaa cgattcttgc cgcttcagtt cggcaataag
    11521 ggcagacgac tggcatttct ttatcattat gttcgactac attattgact tcttcgtatg
    11581 caaatttttt tccgcaatta gggcatttca ttttttccat gttatctcaa cttcctttca
    11641 tctttactct cttagcttac tcttatattg taaaaaagag aagcaatatc cttcttctat
    11701 gcagatatcc atacctgacg gtcctgttct ccatctatta atcggacttt ataataagga
    11761 cgttcatctt tgactagaag tgtccactct ttcacttttg cttttttccc gtagtagctg
    11821 actgcttcct tcatcgctgc ttgcggttgt ttgaactctt ccgttttttc tatatcaaaa
    11881 agatgttctg cggccttttc cgtgtcattt cgtacggttg ttttcccagt ggatggattg
    11941 actgctatga cttgtccttc acaaaaaaac tggtattcat atgttgcatt cgtaggattc
    12001 tccaaatctt tttcaactgc aaaatgaata gcagatatgt tatgttcttt tgtttcgttt
    12061 tttacgattg ctgctgcttt tttcaatgag atccgatatt cctggtcact aatatcatcc
    12121 atgtgaaaag cggcattgag cagtcccgtc ataccggtaa tccctattac gatgagggca
    12181 gcaacaccaa acatcatttt tttcattctt cattctcctg tttctttttt ttaaagaata
    12241 tcaagaaatg aacgaatgaa aaatcgaatg aaacgaaaaa aaagtgacaa ttttgttatc
    12301 tttattcgtg cagttctaat ggcaatccgt ctggatcaaa gaaaaacgtc attttttttc
    12361 ctgtaaaggt atcttctcta atcggttctg attcgatccc taaggactgc aattctgcaa
    12421 ttgtttcttc aatatcgtct actttgaaag caagatgacg caagccacaa gcttctggat
    12481 agtttggtcg ttgtggcgca ttagcaattc caaaaatctc caattcagca cttcctagtt
    12541 tcagatctaa tttatagtca tctcgttctt tgcggtaatt ttctctgatt acttcaaatc
    12601 ctaatttatt aacataaaaa tcacgtgatt tctgataatc tgaaacaatg atggctatat
    12661 gatggatcgt tgtaaggttc atatgagcac tcctattctt cgtttaagct cggatctata
    12721 ttaatctcca gttccattgt aaatgtgtca gattgaaaaa aatagctgtt tttccttttt
    12781 ataagaaaaa aggcaaaaaa aacagaaagt aggtcctcca agacactctt cctgttccca
    12841 atataataaa tgaaagtaag aaattatatt ttcaagaaaa caaacagaaa attatcataa
    12901 cacaaattat ttataattga aagactagtt ttttttcaag aaaagcatac aatagattgt
    12961 gttagtaaat acagaacaca ctacatttag tgtcttaagg agtcctcata catgaagtca
    13021 tattttcagt ttttagctca tcagctaaaa ggctggccgc aacaaaatta ttatcttttc
    13081 tttttcagtc ttggctgcca ggtcatgact cttgtcaata gtcccatcac ttggctgtcc
    13141 gttattacat ttatcggtac cacgcttggt gtattgtgta ttttatccat caatgcggca
    13201 aaatcagtca acggtatttt aggtattttg tctgcgattt gttttattat cgttgggttt
    13261 tcagcaaaga actatttaag tatcggtgaa cagattgctt atatgatcac attggatatc
    13321 cccgtattgt taagtaaaga atggaatcat aatatggctt caaaaatccg aaaattcact
    13381 ggaaaaagct ggtttatcgc aatcatcagt actttccttg tctatcttgt ttcaggattc
    13441 ctgattggtc gttatacaga tgatcctcgg ccgtgggtag atgccattgc tttttctatt
    13501 agcttgactg ctggtatcat cagtttcttg cgttacaaca accaatatta ctggtggtta
    13561 gcttcagggc ttgctcaaat ggtcctttgg tatatttcat ttacgcatgg atctgcaagt
    13621 ttggcgatgt tcgtgaacag ctctgtttac ttgctgaatg atgtccttgc atttaccgtt
    13681 tcaccttggt ataaccaaaa agaacgtgaa cgtatgcaaa aaatggaaga agaatactac
    13741 aacgcacaac aacacgcata aaaaaactga gcgtgggaca aaagtaaaga acacttttgt
    13801 ctcacgctct aaacacgtat aaacggcgga atcagaagca actccttcgg aaataagctg
    13861 aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct tggagttaaa
    13921 cgcttctgtc ccagcctcta ttttttatag taattccttc agatactttc ttgcctcatc
    13981 attgaaacgc agtgattctt ctaacttctg ataatattcc aacgcttgtt tctgagcttc
    14041 agtaaaacga taatgttttc ctttccattt gtcgattgtc tcttgcacat ttccagattg
    14101 gatatctttc actactagtt gccatttttc ttttgagact gtacggtctt tcttatcagc
    14161 agattgtata gcttctcgtt ctttacgcaa tacttttaaa aaaccatttc tgactatccg
    14221 aggaatgctg tcgaagaacc cttctgtaaa accatagcga caatattgct tccaaataaa
    14281 tagatagatt tttggttgga tgaatcgttg gtttttcgca aaatattcca tctgagcagt
    14341 gacttctggt gttcgttgac gttttgtctt tctcaacacg gaaataaatg tttcaaaata
    14401 agcattagga tgtactggca cttcttcata tacgatggat tgccaatctt tacgtaaaaa
    14461 tgcgcgatag ttgatcaaga attcttctac atcctttact aattcttctg caaagtcgtc
    14521 aaatagttct ttttttatct gtcgcttttt tgactgccca ttgatgtgtt cacttatttt
    14581 cttgatttca ttttccaatg cttgataatc cgctatgtaa atcggcattt ctacttggcg
    14641 aaattctgcg agccgctgag ctaattttat atccggtaaa tatggctgtt tcatccgacg
    14701 attttggtac aagacaaaac agtatttttg ccatagtcct tcaggaaaat cgatattctt
    14761 ctgcttaagc cataataatt cgtctaaggc cagatcaact tttgtcattc cctgatggat
    14821 cgaagctgcc actgtcggag agacatgcag gtgatcggca aagtggttga tgcctagttt
    14881 taggatcttt ccggtttttg gcgatttaac gatgtattgc acttttaatt ctctaccaca
    14941 ctcacaatac aatttttgct ggcttcgttt tgttcgaaaa aacggattga tcttgaagtc
    15001 agaaaacacc caatctgttg cagctaaata atgttcttcc ataaaacgag agctgattag
    15061 atatcggcgg tgcttatcga ctagttcccg ctgttttttc gttaattttg catagatctc
    15121 ccaacgttga ctgcttgtgt attgtttaga aattttgatg ggatagcttt tgctgatttc
    15181 ttttggaaac cattcttcaa agacggattg ccattcttcc acggctgttt ctttcctttc
    15241 taattacaaa aagctggcta ctaacataac gttagcaacc agccagtgtt tcttgctaaa
    15301 ttagtgagtt gttccggcat ttccggaaat atcttcttta ttttctactg ctgcttcaac
    15361 tgcataagtc aaagaagaag caatgtcttc taaagacata gaaggcgtac ccactggacg
    15421 atcgatcact tgatcgggtg agaatggcac gtggatgaac ccacctcgaa ttgccgggaa
    15481 ttgtgtttcg atcaaatgaa gcaaacgata catgatatca ttgcagacaa atgttcctgc
    15541 tgtataagag atgtacgctg gtagaccatg atcttgtaca ttttttgtca ttgctttgat
    15601 tggcaatgag gtaaagtaag cggctggacc gttttcttct aaagccgtat cgaatggctg
    15661 atttccttca ttatcaggga ttcttgcttc tgctagattg attgcgacac gttcgaacga
    15721 gactgctgac cgcccacctg cttgtccgac acagatcacg acatctggtt ggtgctgttg
    15781 gatggcttct ttgactactt gactgctttt ttcgaatacg gtcggtactt ccactttgat
    15841 gatttcagca ccgctgattt catctggcat tttttttact gcttcatagg ctggattcac
    15901 tttgtcccca ccaaatggat caaaacctgt tactagtact ttcatctgtt gttcctccgt
    15961 ccgattgatt taacatatgg ttatctttta tcataccatt ttccttgaac agcgtaaata
    16021 aaggaaacaa tagtttaaat aacataacag atcaaactta atatattctt ataaaaaaat
    16081 agtgttccac tacaatgtta gaagaggttg cgacaattat tctgtcacaa cccctctctt
    16141 ctattattta aatagaatca tataagcaat ttggaaaact agcataaata acgcaataaa
    16201 caactggttt ttgatcactc cgtatttgtc tttcatctcc agcatcgcta caggcacgat
    16261 attgaagtta gcagccatcg gtgtcagcag ggtcccacaa aaaccgcaag tcaatgcaac
    16321 cattcctatt aacgctggat tcgctccatg actaaatacg aatggtgcac cgatcccaac
    16381 cgtcatcacg gtgatggccg caaatgcatt ccccatgatt accgtaaata tcaccatgcc
    16441 aagagcgtaa atgatgatgc cgatgttcac atttccttct ggaacgatcg tacctactgc
    16501 attggaaatc actgtcccaa ctccagcgct tgtaaatacc gcacctagag aagctaaaag
    16561 cattggcaac atgcttaacg gccctactgt gcccagcata tctgctgcat catctaaaaa
    16621 tgtacttggt cgattatctc gagaaaagaa catcaagatt agcatggctg caaaaacacc
    16681 gacgcccacg ccgactaaag cacctaaatt ggtaaataga gcaaacaaga tcgcaaagac
    16741 accgatactc aaagctggaa taaaaatttt cattcctagt ttgtctgaca ttttttccat
    16801 atattctttt gatggaagcc ggctttctcc tttgctgact ttcttagcaa ttgctggtat
    16861 ggtcatcgca aagatcaagc caccgttcac gattgccgga agccatcttc ctcctgcaat
    16921 aactacccct aagaccgtcc agaaaaaggc tgacccataa cgatgaggat tggttttatc
    16981 tgttaaattt cttactccag tgtaaatcaa tacgagtccc atcacgatat aaaggatctc
    17041 cagtaattta tcgcctaata aaatatcagg atttgtaaaa aagtccatct tattgcccct
    17101 ttcctggata atatttcttc gctaatttct tttctttaag atagaagtag acacttgcca
    17161 caactaaagc cgtgatagcc actggaactt ccactaaagc aagctgtccc aatgttacgt
    17221 catatcctag atctttcagt gttgattgga ctagcaacgc ccctgctcct ccgatgaata
    17281 gtacttggcc aaagaaccag cagacatttt ccatagctga agccatacct tttagttctt
    17341 cttcatgctt aggatggact tctaaccctt ttgattcgat ggtccccaat gccatcggta
    17401 aaatgattgg acgaacaaat ccagcaactc caccaaaact cacgttaaaa gccgcaaaga
    17461 tcattcgaaa gatcccataa atatctacaa tcataccagc agatactttc ttgaatcgct
    17521 tgatcaagga agccgctgat tctttcagac catttctttc aagcgttcct gttgccaaca
    17581 taatgatgat aaaaatcgcc atcccgcgat tgtttacaaa acttgtacct aaaagttcta
    17641 acattccttg aatgccaaga ccgccagtca aagctgtaac aactaaagca accattacga
    17701 tcaatatcga gtctaattta aatgcaaacc cgagaataac aatcaagacg cctaaaaggc
    17761 taagataatt ttccatatat tttcctccat aaaatgaca
//
LOCUS       DADVXB010000054        17573 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.055, whole genome shotgun sequence.
ACCESSION   DADVXB010000054 DADVXB010000000
VERSION     DADVXB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.055"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            11..241
                     /locus_tag="KB902_001410"
     CDS             11..241
                     /locus_tag="KB902_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBB6808247.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            338..1639
                     /gene="murA"
                     /locus_tag="KB902_001411"
     CDS             338..1639
                     /gene="murA"
                     /locus_tag="KB902_001411"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6808248.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1652..1828
                     /locus_tag="KB902_001412"
     CDS             1652..1828
                     /locus_tag="KB902_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6808249.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1963..2259
                     /gene="yidD"
                     /locus_tag="KB902_001413"
     CDS             1963..2259
                     /gene="yidD"
                     /locus_tag="KB902_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBB6808250.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2443..2910
                     /locus_tag="KB902_001414"
     CDS             2443..2910
                     /locus_tag="KB902_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808251.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2995..3879
                     /locus_tag="KB902_001415"
     CDS             2995..3879
                     /locus_tag="KB902_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6808252.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            3993..4229
                     /locus_tag="KB902_001416"
     CDS             3993..4229
                     /locus_tag="KB902_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBB6808253.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4317..4397
                     /locus_tag="KB902_001417"
     tRNA            4317..4397
                     /locus_tag="KB902_001417"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4351..4353,aa:Tyr,seq:gta)
     gene            4404..4475
                     /locus_tag="KB902_001418"
     tRNA            4404..4475
                     /locus_tag="KB902_001418"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4436..4438,aa:Gln,seq:ttg)
     gene            4600..4770
                     /locus_tag="KB902_001419"
     CDS             4600..4770
                     /locus_tag="KB902_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808254.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            4990..5697
                     /locus_tag="KB902_001420"
     CDS             4990..5697
                     /locus_tag="KB902_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6808255.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5757..6401)
                     /locus_tag="KB902_001421"
     CDS             complement(5757..6401)
                     /locus_tag="KB902_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBB6808256.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6528..6815
                     /locus_tag="KB902_001422"
     CDS             6528..6815
                     /locus_tag="KB902_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808257.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6923..7243
                     /locus_tag="KB902_001423"
     CDS             6923..7243
                     /locus_tag="KB902_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808258.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7324..8637
                     /locus_tag="KB902_001424"
     CDS             7324..8637
                     /locus_tag="KB902_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6808259.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8634..9353
                     /locus_tag="KB902_001425"
     CDS             8634..9353
                     /locus_tag="KB902_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBB6808260.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9481..10032
                     /gene="raiA"
                     /locus_tag="KB902_001426"
     CDS             9481..10032
                     /gene="raiA"
                     /locus_tag="KB902_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBB6808261.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10254..12788
                     /gene="secA"
                     /locus_tag="KB902_001427"
     CDS             10254..12788
                     /gene="secA"
                     /locus_tag="KB902_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBB6808262.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            12915..14016
                     /gene="prfB"
                     /locus_tag="KB902_001428"
     CDS             join(12915..12986,12988..14016)
                     /gene="prfB"
                     /locus_tag="KB902_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBB6808263.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14121..14807
                     /gene="ftsE"
                     /locus_tag="KB902_001429"
     CDS             14121..14807
                     /gene="ftsE"
                     /locus_tag="KB902_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBB6808264.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14791..15684
                     /locus_tag="KB902_001430"
     CDS             14791..15684
                     /locus_tag="KB902_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808265.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15836..17284
                     /gene="cls"
                     /locus_tag="KB902_001431"
     CDS             15836..17284
                     /gene="cls"
                     /locus_tag="KB902_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6808266.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
BASE COUNT         5880 a         2986 c         3842 g         4865 t
ORIGIN      
        1 ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga gtcatttggc
       61 gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt ttttcagacc
      121 aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt tagggtacac
      181 tgcaagtaat tttttcttag aagttatcgc tttatgccga aatcttttcg ttagcctgta
      241 aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa gattttgagt
      301 aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca tcgtaagagg
      361 tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg ttttgcctat
      421 tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg ttccgattct
      481 ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg tagattttga
      541 tgaacaaaag aatcaagtaa caatcgatgc ttcaagacaa ttagaaatcg aagcgcctta
      601 tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac ttgccagaaa
      661 tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac caatcgattt
      721 gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg gctatatcga
      781 agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta gtgtaggtgc
      841 tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca ttgaaaacgt
      901 agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg gcgctcaagt
      961 ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac atgcagtcaa
     1021 ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg ctgcaatgac
     1081 acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat tgatttctaa
     1141 attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg tcatcggacc
     1201 aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc ctacagatat
     1261 gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtag tgactgaaac
     1321 agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg ctcatgtcaa
     1381 aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg cagaagtata
     1441 tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag caaatggaat
     1501 cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc atatcaaact
     1561 acagcaatta ggtgcagacg ttgaacgtgt agacatggat caaacttctg ctgaaaaaac
     1621 agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata tcttattaac
     1681 tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg ccggaacgat
     1741 gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc caagtttgtg
     1801 gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc tagtcgatat
     1861 gaagtgagcc atgaagcaga acatgacaaa agaaaacaga agggaacgtt gacgttagtc
     1921 gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa gatattgatt
     1981 tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag ctgccgttat
     2041 tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc actaaaaggg
     2101 acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg cggtatcgat
     2161 tatgtaccat tgacattcca attaacgcga aataagaaag ataaaaaaga accagattat
     2221 aaaaaggttg tgaaaaatac gagtagcact gagcgataaa gaaacaattt ggaaaatagc
     2281 ttcttatatt ttgcaaaatt gtgagttatt gccgaagtgt tggattttga acaccgtcaa
     2341 aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg aaaattattg
     2401 tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga agaactaaac
     2461 aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga aaaagttcaa
     2521 gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac aataggtgta
     2581 ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt agccccaacg
     2641 tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa gctttcacaa
     2701 ctcgcttcca gtcaaactca gatcatcata cgaaccggca gtactagcag tgcggcgtta
     2761 catctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta ttttatccat
     2821 cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt aattttagca
     2881 attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa atgctttcaa
     2941 atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat ttttatggga
     3001 atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga tggcaaagag
     3061 attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa agcgcaatta
     3121 tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg aatcagctct
     3181 cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat tccttatatt
     3241 catggattta atattttccg agatttggaa actctgtttc aactcccagt aacgattgaa
     3301 aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg tgattatcaa
     3361 gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac gaaaggacaa
     3421 atcaataaag gggcacatct ttatggtgga gaatttgggt tgatgttctt aaatggcgat
     3481 aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg tgaacgcaaa
     3541 ggtctcgata aaaattctta taccggaaaa gatgtctttg aattagcaga aactggagat
     3601 gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg attattcagt
     3661 attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggtgtttc tgcaaaagaa
     3721 gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt cgatctgcat
     3781 gatttcgaac cgcagatttt attatgtgaa tacagaaacg atgctaatct tgtaggtgca
     3841 gcagcaaact atctcgctgt acgtcaaggg gagaattaag agctttagag aaggtgcagc
     3901 ttgcataaaa gaagtgaatg aaatgaatag gagattttta cctaaggaat gttttatttg
     3961 ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat aaagatgttg
     4021 aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa gtcactcagt
     4081 tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa gaatatgaaa
     4141 ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg atagaaacag
     4201 tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc aataaagggt
     4261 tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa cctttcggag
     4321 gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt tcagtggttc
     4381 gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag ggactttgac
     4441 tccctcatgc gttggttcga atccagctac cccagtatac cacaatcgta agctctcgtt
     4501 agttcgagag ctcttttttt tgctttgcta ccttgttcct tgaagattct gctgatttaa
     4561 gatagagtta agttaactac aagaattgga gggatccaca tgaaatggaa agaaaaagta
     4621 gacgaagcag ctgaaaagtt atatgatttg gtcaaatcag aaaaatacaa tattgaagtg
     4681 aatattccga aaaaaggcgg aaaagcggtc caggtaaaat caaaacgccc aacgaatcat
     4741 acaaaaaaat ggatggctaa aaaccgctaa taataacaaa agatccataa gtcggcattt
     4801 tcatcgattt tagggtcttt tgttattttc taggttgaac atatctaaaa aattgtttct
     4861 gacaatagga gtaggaagaa cgatgtgtgt ctaaatcctc tgttgatgga tagaaacctt
     4921 tatctttttc agttgtgaat caggtatata ccagttataa tagaagaaac gaaaggacgg
     4981 gtgtacgtta tgtcgaatca attacctgta tatatacaga ttcatgacca attaaaaaat
     5041 gaaatcgaac aaggtatatg gaaagtcgga gaccgtcttc cttcagaaag agaattagca
     5101 gtgaaattca atgtcagccg tatgacgttg agacaagcaa ttcaaaactt ggcagatgaa
     5161 ggaatcttag aaagaaagat cggttcgggt acatatgttg cgcgagaaaa agtacaagaa
     5221 aaaatgtctg gtgcaacaag ttttacagaa attatggaat cgcaaaatcg agtaccgtct
     5281 agtcggacaa tctcttattt cttgacttcg ccaagctcaa gtgaaatgga aaaactaaac
     5341 ttgagtaaag atgacacgat cttgcgaatg gaacgtattc gtttcgcaga tgatgtccct
     5401 atttgttttg aagttgccag tgtgccacaa aagctgatcg atggctacag caaagcagag
     5461 attactgaat cgttgtatcg cacgctagaa gaaaaaggcg ggaaaaagat cggtccagcg
     5521 aatcaaacga ttactgctgt gttggcttct gagaaaattg ctgactattt agaggtaaaa
     5581 cgaggagatg cagttcttcg tttgcgccag atttcttatt ttgaagacgg tacgccgttt
     5641 gagtatgtgc gtacgcaata cgtaggaaat cgttttgagt tttatttgga aaaataaaaa
     5701 acaggtgatc cctgattcct tacttagaaa taaaagagaa tcagaatcac ctgtttttat
     5761 atatgatcag ttaccagttg ctcgtgataa gaaacaggac cctcttcaaa ttggacttgt
     5821 ccgttcagca gctcaatgat ggattcttta aagtggtcag cacttttttc atctacagca
     5881 cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg ttggagttca
     5941 agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat ctcctgttgc
     6001 aaggtacctt ctacgattcc aatgtcagac aatgcttgag agacagcatg agtgtatgct
     6061 cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac tactgcagct
     6121 acattgatca gttgattttt tttgaggact tccaacatcg gtacgccagc cgttccactt
     6181 ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat gaaggcgctg
     6241 cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaact ttttgcttgg
     6301 tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat ctcaatctca
     6361 ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc tctttttttc
     6421 attttcttta ttcagtataa ataaagttct aggttgtttc aacactgtaa cggttgcgca
     6481 atcgctgtag tatgcgataa taaagacaaa ggtaggtgga tctggggatg caggaacgaa
     6541 tgaaaaagta cgatgcaatt acgcattatt tgaagaacaa tggcggctct caagtaacgt
     6601 tgacctttac ccaatttgac gaactgctgt ttcccagtaa cggacttccc aaaacagcaa
     6661 gggaaagtac agattggtgg gcaaatgatt ataaacaccc tgaaaaaggt gcctatggct
     6721 ggataaatgc aggctatgaa gtagttgtca tcaatttgga caaagaatat gtcgtgttca
     6781 ataaattagt gaaatctagt tggctatttg attaaataaa ccgcgtttag aaaacgttga
     6841 caaatttctt tctttttata taatagagta acagacgcga agaaaacgtt tgcgtagttt
     6901 gttttaaaaa ggagagaaaa gtatggctaa aaaaacaatc atgcttgtat gttcggctgg
     6961 tatgagcaca agtttactag taacaaaaat gcaaaaagct gctgaagcaa aaggaatcga
     7021 ctcggatatt ttcgctgtgt ccgcttctga cgcagataac aatcttgcaa ataaagatgt
     7081 agatgtactg ttattaggac ctcaagttcg ctttatgaaa gctgattttg aaaaacgtct
     7141 ggaaccaaaa ggcattcctt tagacgtcat caatatggct gattatggta tgatgaatgg
     7201 cgaaaaagtg ttagatcaag caatcacgct cataggtgaa taaatagaac agtataacta
     7261 tcgaacaagc gatccaaaaa atagatcgct tgttttttcg tatatttttt tagggcgaat
     7321 aatatgaatc atttttgggg tagaaggctt ctgacgagag atattaaagc aatagactgt
     7381 gaggaggtaa atttaccaaa ttatgagaag atcgcagcag tggaacgttt gggcaactgg
     7441 attctttgtc atcgctgtgg aatgaggacg tccgtcattg atggacagct tgcagattac
     7501 ggttattttt gtacacattg tctatattta gggcgatgcg acactcaaca agatttatat
     7561 ttgtttgatc agcctgaagc aaaacctcga gaagtcgtct ttttttggac aggacagctt
     7621 actgaaaaac aaacggaaat cgcaaagaga atactttgcc attcagaaaa aagacatcat
     7681 cttatttggg ctgtaacagg tgcagggaaa acagagatgc tttatcctat tttagtggaa
     7741 actttaaaag ctggaggaag agtagcgatt tgtacaccgc gagtcgatgt ttgtaatgaa
     7801 ttgtttttac gctatcgtta tgtttttcca gaagaaaaaa tcacgttgct ccatgggaat
     7861 acagcaacgg cttatacctt tacttctttt gttatctgta cgattcatca gctataccgt
     7921 ttttatcggt cctttgattt aatagtgatc gatgagatcg atgcgtttcc ttataacggg
     7981 gatgcaggat tagctcatgc tgtgcaaaca gcgattaaac cagacggacg attcatctac
     8041 ttaagtgcca cacctgataa aaagttacta aaggaaatca agcagacgtt tgacatccac
     8101 aaacttgctt tgcgctttca tcggcgttta cttcctgaac ccgtcttggt tttcatgaat
     8161 aattggcgac aaaaatgcaa gaacaagaag aagataaaat ctttggtgcg gatcattcat
     8221 caattaatta aagaaaacca tatcctttta ttttgtccaa gtatcacgat gatgcatcgt
     8281 ttgaaagcca cacttcaaga ggctcttccg agatatgaga tcacagatgt ttcttcaaga
     8341 gacaatcagc gggcggaaaa agtccagaaa atgcgagaag caaaatatga catactgtta
     8401 accacgatga tccttgaacg tggagtcaca tttgaaagaa tatccgttat cgttttagga
     8461 gcggatcatc cggtttttac taaatcttct ttggtacaaa tcgcaggaag agccgatcgt
     8521 aaagggcctt atacgaacag tcaagtatac tttttctatg aagaaaaaac tgcagctatt
     8581 cgaaaagctt gtcaggaaat caaagaaatg aatgaagaag ggaagaagat gctgtgaggt
     8641 gcagttgctg cagtaaagat atcgtccaaa atttaacatt cagcgagatt attggtgttt
     8701 cgaaatacag attacctcag acttgttcag tttgtcgcgc acaatttcat ttattggaaa
     8761 caagaggctg ttctggctgt caaaaaccaa tccatttcaa tctagagagt acgaaaaaga
     8821 aagtaaagtc tattcccgtt tactgcagtg actgtcaaga atggaagaag aaatatccga
     8881 cctatgattt tcagcaccgt gccttttttg tgtacgatga aaatatgaag gcctggctca
     8941 atcaatacaa gtttatggga gatatccgac tagcaggcac ctttgcatat aaatggacgc
     9001 agataaaaaa agaatacccg acatacatct attgtccaat acctttatct gaaaaaaggc
     9061 gaacagaaag aggattcaat caagtaagcg agatgttgaa agcagcaaga attccttttc
     9121 agatgctact caaaagagag aagcatctgc tggctcaagc aaaaaacacg cgaaaggaaa
     9181 gattggagat gcctcaacct tttgaacttg cagtcacctt ttctaagata caaaataaaa
     9241 aaatattgat tattgatgat gtctatacaa caggacagac tcttttccac gcagcagatt
     9301 gtttgcaggt cgcacagccg aaaatcatcc gaaccatttc tttagcaaga tgaattagat
     9361 gtggaaattt gatagcgatt taatttgcaa ataacctaga gttcgatata atagaattaa
     9421 gaagagggaa agagtggtcc ttctccttct tgattgtggt agacgaaagg ggtaattttt
     9481 atgtttagat ataatgtacg cggcgaaaat atcgaagtaa ctgaagcgat tcgcgactac
     9541 gttgagaaaa aagtaggcaa actagaacgc tatttcagtg acgcacccga tgcaacggcg
     9601 catgtgaact taaaagttta tacagaaaaa acagcaaaag tggaagtaac gatcccatta
     9661 ccttatcttg tattacgtgc cgaagaaact tctccagatt tatacgcaag tatcgatttg
     9721 gttgttgaca aattggaacg ccaaatccgc aaattcaaaa caaaaattaa tcgtaaatcc
     9781 cgtgaaacgg gcatgaatac tgcagatgct actgctttat tcaatgaaga ggacgaaaac
     9841 gaaaatgatt ctgaattaga tatcgtacgt acgaaacgcc tttcattgaa accaatggat
     9901 agtgaagaag cagtcttaca aatgaacatg ctgggacata acttctttat ttttgaagat
     9961 gcagaaacaa atggtacaag tatcgtttac cgccgtaaag atggaaaata cggactgatt
    10021 gaaacagact gatcagcctt acttaaataa caacgaaaac ttgcagcagc tactgacagc
    10081 tgccgcaagt ttttttgagt ttcctcctct tttagatgaa atatgaataa attatgaagt
    10141 tcttacttta atacgcttaa gatatttcaa ttatctataa ctaatgataa aatgaaaagt
    10201 aaagtctaca tagtctggat aatacacaga aggaaaagga gattacacaa cgcatggcca
    10261 atttgattcg ttcacttatc gaaaacgata agaaagaact aaaacgttta gatagcattg
    10321 caaaaaaagt tgaagcatac gctgaccaaa tggcagcatt aactgatgaa caattacagg
    10381 caaaaactgc tgaattcaag ggcagatacc aaaaaggaga aacattagat caattacttc
    10441 cggaagcttt tgcagtcgtc cgagaagcag caaaacgtgt attggggtta tatccatacc
    10501 acgtacaatt aatgggtggg atcgtgcttc acgatgggaa tatccctgaa atgcgtactg
    10561 gtgaaggtaa aaccttgact gcaacgatgc cggtgtatct gaatgcgttg actggcgaag
    10621 gggtccacgt agttaccgtc aatgaatatt tagcaacccg tgactcgacg gaaatgggcg
    10681 agctttataa tttcttagga ttgacagttg ggttgaatat caactcaaaa tcttcggatg
    10741 aaaaacgcga ggcttataat tgcgatatca cttatagcac gaataatgaa ttaggatttg
    10801 actatttgag agacaacatg gtcgtttacc gtcatcaaat ggtacaacgt ccgctgaatt
    10861 atgccattgt cgatgaagtt gactcgatct tgattgatga agcgagaacg ccgctgatca
    10921 tttcagggca agcagaaaaa tcaacagctt tatatacaag agcagacaac ttcgtgaaac
    10981 gtttgaaaga agaagaagat tataaaatcg atatacaatc aaaaacaatc agtttaactg
    11041 aagcagggat cgaaaaagct gaagaaacat tcggtttgga caacttatat gacattgaaa
    11101 atactgcatt gacccatcac ttggatcaag cattgagagc caactacatc atgcttttag
    11161 acatcgatta tgttgttcaa gatggaaaag tattgattgt tgaccaattt acgggtcgga
    11221 tcatggatgg acgccgttat tcagatggtc ttcatcaagc gatcgaagct aaagaaggcg
    11281 tagagatcga agacgaaacg aaaacgatgg cgacgatcac tttccagaac tatttccgta
    11341 tgtacaagaa acttgcgggg atgactggta cagctaagac agaagaagaa gagttcagag
    11401 agatttataa tattcaagta taccagattc cgacaaaccg tccggtcatc cgtgacgatc
    11461 gaccagattt gctttaccca acattacaaa gcaagttcca tgctgtcgta caagatatca
    11521 aagatcgcta ccgcaaagga cagcctgtct tagtcggaac tgttgcagtt gaaacatctg
    11581 agttattatc agatatgctg aatcaagaac gtattcctca tgaagtactg aatgcgaaaa
    11641 atcactttaa agaagcagaa atcatcatga atgcgggtca aaaaggtgca gtgacgattg
    11701 ctaccaacat ggctggtcgg ggaacagata tcaagctagg gcttggcgta agagaacttg
    11761 gtggcctagc agttatcggg acagaacgac atgaatctcg tcgtatcgat aaccagcttc
    11821 gaggacgtgc aggacgtcaa ggagaccctg gtatgtcaca attctacttg tctttagaag
    11881 atgatttgat gaaacgattc ggttcagaac gaatcaaagc tttcttagat cgaatgaaga
    11941 tcggtgacga agatgctgtg atccaaagca agatgctgac gaaacaagta gaagctgcac
    12001 aaaaacgcgt agaaggaaac aactacgaca cacgtaagaa cgtcttgcaa tacgatgacg
    12061 tgatgcgtga gcaacgtgaa gtaatctata aacagcgtca agaagtgatc atggaagaaa
    12121 aaagcttatc taaaccactg atgaatatgg tcaaacggac aatcagtcgt gtggtagatg
    12181 cgcatacgca attagaaaaa gaaaattgga atttggaaag tatcgtcgat tttgctggca
    12241 gcacgcttgt ccatgaagac agtatttccc ttacagatat cgaaggaaaa acctctcaag
    12301 aaatcaaaga atatctaaac gaacgagcac aagaagtatt caataccaaa gcagctcaat
    12361 tgaacggacc agagcaactg cttgaatttg aaaaagtcgt gatcttacgt gtcgtggact
    12421 ctaaatggac agatcatatt gatgcaatgg accaattacg tcagtcaatc ggcttgcgtg
    12481 cctatggtca aaacaatcca ttagtcgaat accaaacaga aggttataag atgttcgaag
    12541 atatggtagg tgccattgaa tatgaagtca ctcgtatctt catgaaagct gagatccgtc
    12601 aaaacgtaca acgtgagcaa gtttctcaag gaacagcttc tcactcagaa gatggagatg
    12661 ccaaagaaaa cagtaatact agcgcgaaaa aacaaccaat ccatgtgaac aaggttggta
    12721 gaaatgatcc ttgtccttgt ggaagcggga aaaaatataa gaactgtcac ggaaaagatg
    12781 caaactaatt tctgacagca ggattggtga gacaaattct tttttaaaga atttgtctca
    12841 ccttctttct gttatttgac gattctgtta gactagatat aataaaaaaa gtatagtgaa
    12901 agaaggaaaa aaacatggaa atatccgaaa ttcgaaatct cctgacagaa atgcaggaaa
    12961 aggtcacaag cttcaggagg tctctttgac ttagaccagc tggaagaaga cattgcggaa
    13021 gcagaagcaa aaatggctga acctggtttt tgggatgata gcgaagctgc tcaaaaagtg
    13081 atcagtgaaa acaatgcaaa taaagaaact tatgatcaat tccattctct tgctgaagaa
    13141 ctggaagaaa tcgaattgat ggtggagatg ttgcaggaag aacctgatgc agtaatgcaa
    13201 gaagaagcag aagcacgtat caatgcgcta gatgaaaaaa tgaatacgta tgaattatct
    13261 atgttgttag atggtcctta tgatcgaaac aacgccatcg tcgaattgca tccaggggct
    13321 ggcggaacgg agtcccaaga ctggggcagc atgcttttac gcatgtatac acgctgggca
    13381 gagcagcatg ggtatcaagt agagacacta gattatcaag caggcgatga agcaggaatc
    13441 aagagtgtga ccctactgat caaaggacac aacgcatttg gctatctgaa atcagaaaaa
    13501 ggtgttcatc gccttgtacg tatctcgcct tttgactcag caaaacgtcg tcatacttct
    13561 ttttgttcgg tagatgtgat gccagagctt gatgaaacga tcgatataga aatcaatcca
    13621 gatgatttga agatcgacac atatcgggcg agtggtgcag gtggtcagca catcaataag
    13681 acagaatccg ctgtacgaat cactcacttg cctacaggaa cagtagtagc gagtcaggca
    13741 caacgttcac aattgaaaaa ccgggaacaa gcgatgggga tgctgaaagc taagctttac
    13801 caattagaag tggaaaagaa agaacaagaa gcagctgcac tgagaggaga acaaaaagaa
    13861 atcggctggg gatcacagat ccgttcttat gttttccatc catattctat ggtaaaagac
    13921 catcggacaa acgtagagac aggaaatgtc caagctgtta tggacggaga tcttgattta
    13981 tttattgacg gctatttgaa aatgcatctg caataagagc cctttgttaa attgaaataa
    14041 aattgtaaga ttttgcaagc aagttgaaac attgccatgc tataatagct aaagactgaa
    14101 aaagatatgg agagaacgcc atgattgaaa tgaaggatgt aatgaagaag tactcaaacg
    14161 gtaccactgc tatccgcaat ctctcgattg tcatcgaaca aggagagttt gtgtatgttg
    14221 ttggtccgtc tggagctggt aaatctacat tcatcaaatt gatgtatcga gaagaaaaag
    14281 cttcaaaagg aactttgaac gtcgcaggtc atgatctaat agccatcaaa aaccgcgaag
    14341 ttccttatct acgcagagaa atcggcgtgg tgttccaaga ctataaatta ttaccaagaa
    14401 aaacagtata tgaaaatgtt gcgtacgcca tgcaagttat cggcagaaaa cctcgggata
    14461 tcaaaaaacg agtaatggaa gtgctggatc ttgttggttt gaaacacaaa gtccgagtct
    14521 ttcctagcga attatctggt ggggaacaac aacgtgtttc tattgcccga gcaatcgtaa
    14581 atacacctaa agtacttatc gcggatgaac cgacagggaa tctagatccg gaaaactcat
    14641 gggaaatcat gaaactatta gatcggatca atgcacaagg aacaactgtc gtgatggcta
    14701 cacataacag tacgatcgta aatacgattc gacaccgagt aattgctatc gaaaacggcc
    14761 gcattattcg agaccaagcg gaaggggaat atggatacga tgattagaac ctttttccgc
    14821 catttattag aaagtatcaa gagtttgaaa cgtaacggct ggatgacagt agcttcggtc
    14881 agtgcggtaa cgatcacgtt gactttagtt ggtgtgttca tggcggtcat catgaacgca
    14941 accaaactag cacaagatat agaaggaaac gtggatgtat ctgtgttcgt agacattggt
    15001 acaaaagacg aagagatgaa aaaattagaa aaagaattaa atgacttaga tcatgtcaaa
    15061 aaagtcgaat tttcaagcaa agaacaggaa ttgaagaaaa tccaaaacga aatgggcgat
    15121 tcttggaaat tgtttgaagg ggataataac ccgttatatg atgtatacgt agtaagtgct
    15181 accgatcctt cttatacaaa acaagtagca gaaaaagcgg cagatttgaa gaatgtttcc
    15241 cgttctgatt acggtggggc ttcctcagat cggattttcc aaattgctgg tgcagttcga
    15301 acatggggat tagttgcggc ggcattgctg ctgtttgtag caatgtttct catttctaac
    15361 acgattcgga tcacgatttt atctagacag cgtgaaattc aaatcatgcg tttagtaggg
    15421 gcaaaaaatg gatatatccg ctggccattt ttccttgaag gtggttggat cggcttaatc
    15481 ggtgccattc ttccgatact gatcattaca tttggttacg catggtttta ccaattgatc
    15541 aatccgtcat tattacgatc tcattattca ttgatccatc cagaaaatat cgtttggaaa
    15601 atcaatcttt tgatggtcgg tattggtgtg atcattggtt cactcggctc gatcatctct
    15661 atgagacgtt tcttgaaatt ctagtgtcac aagataaata taatcagaaa gttggacgat
    15721 ttcgttccag ctttcttttt ttatcagcta ggtggagtaa atggggcggc ttttttctct
    15781 ttactttaaa aaacaacttg ggtattctta agttggtaga aaaagaggtg aagccgtgaa
    15841 gattatcgtt gacaattttt ttacgatcct tttgattatg aatattttgc tttcctttat
    15901 tatcgttttt cgagaaagaa aggaaactgc gcaaacatgg gcatggctgc tcgttttgat
    15961 gttcattcca gttgtaggat ttattttata tattttttta ggaagaggga tttccaaaga
    16021 gaaaatcttt gatttgaaga tccaagggaa aatcggtaag aatctagaaa tcgaagaaga
    16081 taaacaagca ttgatgcgag ggctttatcc tcatccgcct actggacaag tagatgtgaa
    16141 acaattgatc tatatgctta ctgtatttga aagtacgctt tatacgacta aaaatgaaat
    16201 cactttattt acagatggtc gtgaaaaatt cgatgcgctg atcgaggata tcaaacaggc
    16261 agaagaccat atccatttcc aatattatat ttaccgcagt gatacattag gtgaagaagt
    16321 tcgagaggca ttgacagagg cagcaagacg cggagtaaaa gtcagagtcc ttcttgatgc
    16381 atggggttcc acacaagttt cttctagttt ttttcagaat ttgaaaaaag caggtggaga
    16441 agtcgcattt ttctttcctc tattcgttcc gtatatcaat cctcgaatca attatcgcaa
    16501 tcatcgtaaa atcgtagtga ttgatgggaa aatcggatat acaggtgggt tcaatgttgg
    16561 aaacgaatat ctaggattgg taaagaaatt tggttattgg cgagacaatc atctgcgtat
    16621 ctatggagaa gcggtttaca ccttgcaaaa ccgttttttg atggactgga attctcagca
    16681 tacaaaagaa gtaggatatt caccggaatt tttcccgacc attcattcta caggtgatat
    16741 ggctgttcaa atcgtgacaa gcggaccaga taccgaacat gagcaaatca aaatgacata
    16801 tttgaaaatg atttcgttag ccaaacggga gatattgatc caaacgccgt attacatacc
    16861 ggatggatcg attcatgagg cattgaagtt ggctcttctc tcaggcgtaa aagtccatat
    16921 ccaaatacct aacaaaccag atcatcttct cgtttactgg gcaacgtatt ctttcgctgc
    16981 agagctgatc gagtatgggg caagaatcga aacatatgaa aatggattta tccatgcaaa
    17041 gacgatgatt atcgatggcg gcatcgtttc cgttggttca gctaatatcg acgttcgctc
    17101 atttagattg gattttgaag tcaatacact gatctatgat gaacgaatgg cttctcgcgt
    17161 aagaaaagca ttctttgaag attcaaagat ttcgacgcat ctcacaaaag aagtgtatga
    17221 aaaccgaggg atgatgatca agatgaaaga aggattagca agactgattt cgccgctcct
    17281 ttaaaataca aaaaggacag gagagccatc aatagatgga aatctcgcgt ccttttttct
    17341 cggggccatt tctgagagta cgtcagaaat ggagaaagcg tctcgcatga gcgaaattaa
    17401 ctttggggta tctcttgttt tttggggaaa gcaagaaata agctaatata tgctattaaa
    17461 agagacacat ttcaaagcca gtatagcata gaaactttta atgagatagc tttttttgca
    17521 attatgagaa tttattttgt tatttaatga ttttgattcg ttttcatcaa gta
//
LOCUS       DADVXB010000055        17314 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.056, whole genome shotgun sequence.
ACCESSION   DADVXB010000055 DADVXB010000000
VERSION     DADVXB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.056"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(12..557)
                     /locus_tag="KB902_001432"
     CDS             complement(12..557)
                     /locus_tag="KB902_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6808267.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(569..1261)
                     /locus_tag="KB902_001433"
     CDS             complement(569..1261)
                     /locus_tag="KB902_001433"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBB6808268.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1280..1564)
                     /locus_tag="KB902_001434"
     CDS             complement(1280..1564)
                     /locus_tag="KB902_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808269.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1577..2140)
                     /locus_tag="KB902_001435"
     CDS             complement(1577..2140)
                     /locus_tag="KB902_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6808270.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2368..3030
                     /locus_tag="KB902_001436"
     CDS             2368..3030
                     /locus_tag="KB902_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBB6808271.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3154..4350
                     /locus_tag="KB902_001437"
     CDS             3154..4350
                     /locus_tag="KB902_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBB6808272.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4451..5827)
                     /locus_tag="KB902_001438"
     CDS             complement(4451..5827)
                     /locus_tag="KB902_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6808273.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5864..6730)
                     /locus_tag="KB902_001439"
     CDS             complement(5864..6730)
                     /locus_tag="KB902_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBB6808274.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6819..7844)
                     /locus_tag="KB902_001440"
     CDS             complement(6819..7844)
                     /locus_tag="KB902_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6808275.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7862..8536)
                     /locus_tag="KB902_001441"
     CDS             complement(7862..8536)
                     /locus_tag="KB902_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808276.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8720..9613)
                     /locus_tag="KB902_001442"
     CDS             complement(8720..9613)
                     /locus_tag="KB902_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6808277.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9687..11384)
                     /locus_tag="KB902_001443"
     CDS             complement(9687..11384)
                     /locus_tag="KB902_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6808278.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11377..12690)
                     /locus_tag="KB902_001444"
     CDS             complement(11377..12690)
                     /locus_tag="KB902_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6808279.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12690..16727)
                     /locus_tag="KB902_001445"
     CDS             complement(12690..16727)
                     /locus_tag="KB902_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6808280.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTAINRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16740..17198)
                     /locus_tag="KB902_001446"
     CDS             complement(16740..17198)
                     /locus_tag="KB902_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6808281.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4851 a         3893 c         3013 g         5557 t
ORIGIN      
        1 actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat
       61 tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag tttgtatcct
      121 agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa
      181 taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg
      241 gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa
      301 ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat
      361 aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca
      421 aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt
      481 cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc
      541 gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca
      601 tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt
      661 gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg
      721 tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga
      781 tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt
      841 ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg
      901 cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat cctgttgcat
      961 ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac
     1021 cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca
     1081 gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt
     1141 ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc
     1201 ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca
     1261 tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta
     1321 ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt
     1381 cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg
     1441 caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact
     1501 cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg
     1561 ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa
     1621 tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta
     1681 gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta
     1741 ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg
     1801 aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg
     1861 ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa
     1921 tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa
     1981 aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa gttcctccat
     2041 ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag atttctttgc
     2101 gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct gctttctttg
     2161 taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt attagtttac
     2221 catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc cgatactctt
     2281 tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa ttcaatactc
     2341 aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg gcttctagca
     2401 ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct aggactttta
     2461 ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa
     2521 caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa aagcggtatg
     2581 acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat
     2641 caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct ccgccatgat
     2701 ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa ccgactgcat
     2761 gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac aaataagtat
     2821 aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact agaagaaagc
     2881 gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa attcgttgct
     2941 gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt aaagcgtgat
     3001 aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa gactcggaac
     3061 attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat tcatgtaaga
     3121 atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac tgaaacaaaa
     3181 gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt ttcaactcca
     3241 acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga gcaacagaca
     3301 gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa acagctagca
     3361 gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc tgcccaagca
     3421 aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga tattggtcct
     3481 gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc tgacgaactg
     3541 cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca atcgatctat
     3601 gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc ggtgaaatta
     3661 gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct ttaccagaaa
     3721 aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt gaaaatggaa
     3781 gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac tggcgatcag
     3841 atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga taaacgtacg
     3901 catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat ccgtttgatc
     3961 caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac agccattccg
     4021 ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga tgcagtaact
     4081 gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc agaaatgctg
     4141 aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc
     4201 cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg tatccaaaaa
     4261 gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga agaagatctg
     4321 aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact aaaacaaacg
     4381 cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct tctaacttct
     4441 ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca aaataaatga
     4501 tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc agacgaagca
     4561 tcaatacaat acaagtcaag atggagacga ttggcaatag cggaacgaat ggcactttga
     4621 attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct agactaacaa
     4681 gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc aatgggaaaa
     4741 atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc ggtgtacgat
     4801 gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg acagcaaaca
     4861 gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc
     4921 ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca aaagccactg
     4981 ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc gtcacgatga
     5041 tgtaaaggac agtagcaatc agtatcgaac caatgattcc tcttggcaca tctttttgcg
     5101 ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca
     5161 caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc tgccagttat
     5221 caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca aatttgacat
     5281 ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg atgtaagtga
     5341 cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc ggattgtacc
     5401 cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct tgcatatagc
     5461 cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc
     5521 ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat ggcccaccaa
     5581 tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg acaacgattg
     5641 cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc gcaacccctg
     5701 tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc aaatcagacg
     5761 tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc ttacgaaaca
     5821 aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact gttttcatat
     5881 accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca taaatgagct
     5941 cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag ataatgatcc
     6001 ccatttgtga aagtgagaag ccaacagcta aaccaagtga tttgactgtt agaagcatgc
     6061 agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca aactgatcga
     6121 ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata ctttgaggta
     6181 agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat acaccataac
     6241 caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt ttattatctg
     6301 tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt acaagaagag
     6361 ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg aagaaaacgg
     6421 ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc cctacagaaa
     6481 cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa gctaagccgg
     6541 ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg aaaaagacaa
     6601 ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac
     6661 caattttacc acttactaaa ccaatactac cccatgccaa catagggact aatgctatta
     6721 aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca gcgaaaacgt
     6781 taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc attataaaaa
     6841 tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga ttcagccgtc
     6901 aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa tcctgttgaa
     6961 tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat ccgtttcaag
     7021 tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc
     7081 ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc attactaagc
     7141 aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg atcctcacca
     7201 acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg tatcacaggc
     7261 tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa actgtcgagt
     7321 cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc attttctagt
     7381 aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa tttagaagcg
     7441 gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg gtcttgttga
     7501 ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt gatatattct
     7561 tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa aggggaagtt
     7621 ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc acccagcaga
     7681 taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct caaatcaact
     7741 ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa cagccatccc
     7801 aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct
     7861 ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg atacctgcct
     7921 gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca tctacaaatc
     7981 gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt ccattgtgct
     8041 tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc tctccgttga
     8101 tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc atttcactag
     8161 ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca atcagtacat
     8221 cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc atgatcatat
     8281 ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact tcacgtattt
     8341 tttgacacca ataatagcca tccaaaacgg gaagattaat atctagtaat acaagctgtg
     8401 gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca aaggtttcaa
     8461 attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg tcttcgacta
     8521 ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca atatcaaaga
     8581 agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa
     8641 actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt
     8701 attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt cttttaaatt
     8761 ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga aggagtataa
     8821 gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact tcttctgtaa
     8881 agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag
     8941 tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt tttgttggaa
     9001 ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact tcaagataga
     9061 atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca gcaataccgc
     9121 tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag gtgccttgca
     9181 ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa ggcaagctaa
     9241 cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat tcttttcctg
     9301 gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc attcctggga
     9361 ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat tgttgctcat
     9421 gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt ctttgatcca
     9481 aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa
     9541 acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt ctattaccta
     9601 ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc tttataaaac
     9661 cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga tttacggtac
     9721 cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa gagcccgttc
     9781 ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg ccctggattt
     9841 tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat aaattcagta
     9901 aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc tttcatttga
     9961 taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc gacaaattct
    10021 gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata aacagctaaa
    10081 ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca caattcgaat
    10141 cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt tcttccacct
    10201 gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc atttcgtccg
    10261 atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt ggaaaccttc
    10321 aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc taaagtatct
    10381 actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt gcttactact
    10441 tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc
    10501 tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt tttgataaca
    10561 gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa
    10621 gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc tccagcttca
    10681 ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt atctgcttct
    10741 ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa
    10801 ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac aaccattgga
    10861 gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata gactttatct
    10921 ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc tccagcttca
    10981 ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact ttctgtgtgc
    11041 cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg ttccggtgtt
    11101 aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg
    11161 actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt cggtcgttct
    11221 tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact tggtttttgt
    11281 gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc cgcagtaacg
    11341 agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt ctccccgttc
    11401 tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag aaatcaacgt
    11461 tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg gattgcttgg
    11521 accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat aaacacgtgg
    11581 tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag ccatctcctg
    11641 tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt cagggatgat
    11701 gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt ttaattcttc
    11761 aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc cctctttatc
    11821 cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg gtttgatcca
    11881 ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc cttctatcat
    11941 ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg ttcctctttg
    12001 acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag gatagatatg
    12061 aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa tagcagcaat
    12121 tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa tcgattcttc
    12181 gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga tacgtgcaat
    12241 cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc ctatttggac
    12301 aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag cgatttgctg
    12361 gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat aatcggtcat
    12421 gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga tatctgctgt
    12481 ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa attgatcgtt
    12541 ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat cttcccctga
    12601 ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta aaacaagtaa
    12661 ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt agattgtctg
    12721 acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag caggatatag
    12781 aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt cccgacacta
    12841 agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg ctgtagatca
    12901 ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt acccgcttct
    12961 tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact aatttctaaa
    13021 ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt gatccgatag
    13081 accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc tggtgccaag
    13141 cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga aaattctgcg
    13201 ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc gattggcgct
    13261 agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc ttccggcaag
    13321 ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc ttcattcagt
    13381 gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga ttccgagacc
    13441 tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac atacttttct
    13501 actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga ttcttctggt
    13561 tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc cactttcctg
    13621 atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct aactcggatc
    13681 tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc ctcttcatct
    13741 gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg gatagtccct
    13801 atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc tttgaaacct
    13861 tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc ttcactatcc
    13921 ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc atccacgatt
    13981 acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc ttcctctact
    14041 tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc gttaccatct
    14101 gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc aattagttta
    14161 ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac atacaactca
    14221 tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg atattctcct
    14281 tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc agatgtatat
    14341 tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata ttttttgatt
    14401 tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat ctctctgatc
    14461 caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt cgtttcaaag
    14521 atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc cccactctct
    14581 ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt ttgacccttc
    14641 ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga tgggaaatac
    14701 atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata ggccatattg
    14761 ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg gtacttgatc
    14821 ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg gttttcccgt
    14881 ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg acgttcttca
    14941 tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag atggtaaaac
    15001 tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt ttcatcataa
    15061 agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa ggctgtaaca
    15121 atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc ttctaaatca
    15181 gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc gctaacgttt
    15241 ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata cttgtttttc
    15301 agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga agtaggactg
    15361 ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt attatctcct
    15421 tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg gttaaagtca
    15481 gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga aaactcctca
    15541 aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac agtccagttg
    15601 ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata actgaaggtc
    15661 ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc tccgccattg
    15721 tctttataca atgtttcata gccattttta agccctagtg taagcggagt tcctccgatt
    15781 ggtgtacgat ttattgctgt attctcactt cccgtcaaac gattgatatc atttgtcaat
    15841 ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt atggtaaaaa
    15901 ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt actcatttcg
    15961 tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc ggttaattca
    16021 ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat ttcctttttc
    16081 tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc aggatgtaga
    16141 tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta cgccccgtta
    16201 taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac ggtttgagct
    16261 ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata gtcgtaattt
    16321 cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc tccgtcatat
    16381 ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc taacactttt
    16441 gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac ttctccgcta
    16501 ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc caaaataccg
    16561 ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat tggttcgtcc
    16621 agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc tgtatcagtt
    16681 tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg aagaggtagt
    16741 tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct
    16801 tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc gacttttagg
    16861 tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt tacggtacca
    16921 atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc actttccttt
    16981 ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt cccttcaatt
    17041 tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga ctcagcagct
    17101 acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag caaactgaca
    17161 gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc ctttcaaaaa
    17221 tatttgtctt ctttcacaac aatcaacaaa acaatgccca tctaattata atttaattta
    17281 attttaattt taaatcaaat gatatccttt ttag
//
LOCUS       DADVXB010000056        17113 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.057, whole genome shotgun sequence.
ACCESSION   DADVXB010000056 DADVXB010000000
VERSION     DADVXB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.057"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(296..1024)
                     /locus_tag="KB902_001447"
     CDS             complement(296..1024)
                     /locus_tag="KB902_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6808282.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="KB902_001448"
     CDS             complement(1002..2576)
                     /locus_tag="KB902_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6808283.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="KB902_001449"
     CDS             2805..3743
                     /locus_tag="KB902_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6808284.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="KB902_001450"
     CDS             3755..4666
                     /locus_tag="KB902_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6808285.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="KB902_001451"
     CDS             4690..6162
                     /locus_tag="KB902_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6808286.1"
                     /translation="MKKNMQKYLIGGVSVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6214..6825
                     /locus_tag="KB902_001452"
     CDS             6214..6825
                     /locus_tag="KB902_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6808287.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6855..8768
                     /locus_tag="KB902_001453"
     CDS             6855..8768
                     /locus_tag="KB902_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBB6808288.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8896..11877
                     /locus_tag="KB902_001454"
     CDS             8896..11877
                     /locus_tag="KB902_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBB6808289.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11874..13535
                     /locus_tag="KB902_001455"
     CDS             11874..13535
                     /locus_tag="KB902_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBB6808290.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13575..14507
                     /locus_tag="KB902_001456"
     CDS             13575..14507
                     /locus_tag="KB902_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6808291.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(14867..16432)
                     /gene="guaA"
                     /locus_tag="KB902_001457"
     CDS             complement(14867..16432)
                     /gene="guaA"
                     /locus_tag="KB902_001457"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6808292.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(16487..>17113)
                     /locus_tag="KB902_001458"
     CDS             complement(16487..>17113)
                     /locus_tag="KB902_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HBB6808293.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISN
                     AFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         5437 a         2819 c         3460 g         5397 t
ORIGIN      
        1 atttaaataa ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt acaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgtttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgacga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttta ctaaatgaaa
     6181 agaatagact aagcagttag tggggggatt caaatgaacg aaaacaaatg gaccaaagga
     6241 tttaattggg tttttcaatt gttattacta aactttactt attttatact aatttgttta
     6301 ggatttggaa ttttaggttt tttccctgct acgatagctt tgattgctgg cgttgtgaat
     6361 cgaaaaaaat atggcttgca agagtctgtg aagttcatga gtaaaatcta taagaaaaat
     6421 tttgttagat ataatctata ttgctggtca gcaactttgt tgttggccgg caatattact
     6481 acgatctggc tttgttggca gcaaagcgca ccattgtttt atttattaag tacattatta
     6541 tcggtaatta cactgttcct agtctttgca atgttgaatt gggtcgtgat caaaagtctt
     6601 gggttgtgga tgatgggaga ccgactgatt gactatttgc ttttcacagc aacgatgttg
     6661 ccaacggtag tcatgcaagg cttggtgctt ggaatttatt tccgaatatt gatgattttg
     6721 cctgtgattt ttctgtttgg cggaacagct gtaacggtaa tattgattag taaattaact
     6781 gaaagagcgt tagcaaagtt gccttgtcag atacaatcgc actaattttt tcacaaaaag
     6841 gagtatttct ttctatgaag ttaactgata aacaagtagc taatatagcc tttatccagc
     6901 aacttgagat tccattgaca caaaaagatg aagaacaaat agacttgatt tttactgaca
     6961 caaaggctaa tgtgcgacaa atcaagatta ctaaaaatga gcagcaacga atctgcttgt
     7021 cttattcaca tgaagacttg ctgtatcgag gattgtttat ctgccttcca cgttttttag
     7081 ctcaaggagg agagatgcca tacattgaag aaacctcgat cattgagacc agttattcat
     7141 tagatgcttc tcgtaatggc gtgatgaata aagagactct aaaaaaattc atttcttact
     7201 tagcgttgat ggggtacaac acattgtata tttacacaga agatacctat gaagtagaag
     7261 accttccata ttttggttac cttcgcggag cgtatacaaa agaagaagtg aatgaaattg
     7321 ttgaatttgc ttctggtttt ggcatagaag tagttccatc gatccagacc cttgctcact
     7381 tgacccaatt tttgaagtgg tatgctcaac aagaactgat ggatgatcaa aatactctac
     7441 tgatcggtga agaaaaggtt tatgcggcaa tcgaaaagat gattattgcc tgcaaagaaa
     7501 tgtatcagac agagcgtatt catttgggaa tggatgaagc ctatcaagca ggtctgggac
     7561 gatatttaag cctgtatggg tattgtgatc ggacaacttt aatgattcaa catatggacc
     7621 gtgtgttatc aattgttgat aaatataaga tgaaaccaat gatttggagt gatttcattt
     7681 ataagctatt agatgaaacc ggtaaagata ggtattacaa tcctgatttt aaactcaaag
     7741 cattagcagc taaaggatta ccagcaggat taacctatgt tcattgggac tatggttcag
     7801 atgaagtttc ctcctatgag aaagtaattg ataaccattt gaaattttgt gacattgatc
     7861 attacgtttt agctagtggt gcccatatct gggggagact agccccgaat catgggaaaa
     7921 cagaagcaat tgtttctgca gctgtaaaag cttctaaaaa taaaggtgta cgttctgtga
     7981 tgttaactac ttggggagat gaagggcagg aaacagagca ttggcattcc ttaattgggg
     8041 cattaaaatt agcagattat gtctattctg aagaagagtg gaatgatttt gaggaaatct
     8101 acgatcgttt attaggaaca ggtagttatc aattaatgtc cgaattacga tatttcgatg
     8161 aagtggatac cattacaaat aacaacttac aaatggcttc cgtgagtaaa ctgctacttt
     8221 ggcaagatcc gttagttggt atatatgact ttcatgtagc cgctcataac aaaattgcca
     8281 ctagaacaat tggtacttat tatcatgagt tagctcagaa attagatatg aataaaaatt
     8341 ggaatccaaa acaaccaatt ttaacaacta ttcgtcaacg atatatactt ttagctgaaa
     8401 ttttagcaca aaaggcagaa ctaggcatct atttacaaca ctgctgtctg gtagaagacc
     8461 ttgcaggatt aatggaatta gcgaatcggt gtgaagcact agccaatcga gtaaatgaat
     8521 tggcatctat tcatgaaata atttggtatc aaacatacaa aacctatggt tgggaagtat
     8581 tagaacaacg atatgctgca ttagctcatc gtctgaaaac cgttgcgcgt cgtattaaaa
     8641 atcatcttca ggggcaagat gccctagagg agcttttgga agaacgatta ccgttttgtc
     8701 aatatcaagt gccgcttgaa atttctggct ttaattatcg gcaaagctcg gtgtcaggct
     8761 acaattaacg aaggaatctt cccgttgaac ggaccacttg ctcatctaat gggaaagtgg
     8821 ttcgttttct attcataagt agcttaccac taactctttt attaagaaga gaaaaaaagt
     8881 aggaagtgag aaaatatgtt atcggactat tatcaaaatc tgtcagttat aagtgtcaat
     8941 acagaaccat tacgtaatta ttatattcct tatgcaagta aagaagaagc aaaacaagag
     9001 ttagaaaggg aaaaaacgag ccagtttatc gatctcaatg gtacatggga ttttcagtat
     9061 tatccttctg tccaacagtt accggaaaat ttttttcaag aggcctttac tgaaagttat
     9121 gatagaattt ctgttcctgg agtttggcaa acagagggat ttgacttacc tcagtatatc
     9181 aatgtatctt atccaattcc ttttgatccg ccttatgtac ctaatgatac cccttgtggt
     9241 gtatatcggc gtcagtttca aattgagcaa acagatgcac gcttttactt aaatctagaa
     9301 ggagcagata gtaattgttt tgtttggata aatagaaact ttgtaggcta tgaccaagtg
     9361 agtcatagta catctgaatt tgatgtgacc aagtatttac aggttggggt taatgaaatt
     9421 caaattctag tgatgaagtg gtgtgatggt acctactttg aagatcagga taagtggcga
     9481 atgagcggtc tatttcgtcc agtgtatctt cttcaacgac caactatgca tctgacaagt
     9541 tatcaactac ggacgttgac tgatcctaaa aaaggaagcg gaacattaat ggtttctttt
     9601 caacgattta ctcctattga agtatcgtta cctatttctt acgaattatt ccatcctgat
     9661 ggacgtctca tagcgaaagg ggagtgttac tcggaacaac aaataaattt ggatgttgaa
     9721 gattgccttt tttggacagc agaaacgcct aaattatata cattactttt aacatgtaat
     9781 ggtgaatatt ttaaagaaaa agttggcttt cgagcactga cgatcaagaa tcgtaagtta
     9841 ttgctgaacg gaacacctat taaattatat ggagtcaact atcatgacgt gaatcagcaa
     9901 ggcacgccag tgatgacccg agagcagtta cgtgcagatt tgttattaat gaaaaaatta
     9961 aatgtgaata ctgtacgaac ggcacattac cctaaatcac cagattttta tgaattggcg
    10021 gatgagattg gtctgtatgt aatcaatgaa gcagatttgg agtgtcatgg tgtggttaat
    10081 ctatatgata ctgaagcgaa ttatcaacta attgctaatg atccgacatt cgaaaagccg
    10141 attatggacc gagtgatccg ttctattctt ccttatcaaa atcgaagctc tatcattatg
    10201 tggtctatgg ggaatgaatc tggttatgga gtaaattttg aaaaagctca agctttagca
    10261 cggaaattgg atgattcacg gttgattcat aatgaacgct cgattgaacc agttattgac
    10321 caagtgaatg attttagtaa cttggatgtt attagtcaaa tgtatccccc actggaagat
    10381 gttcatcgtc attgtcaaag aagtgatact gaaaaacctt tttttatgtg tgaatatagc
    10441 cacgctatgg gcaacggtcc tggagatctt aaaacgtact tcgatttgat tcaacagtat
    10501 gattcctttc ttggcggttg tgtctgggag tggactgatc atgcaatcaa tagaggaact
    10561 ttagaaacgc catcttattt atacggtggt gattttggtg aaaaatatca cgacggcaat
    10621 ttttgcgtag atggtttatt gaccccagat cggcaattaa cagtaggtgc attggagtac
    10681 cgtaatattc attcgcctat tcaactgatt gctgtagatg aggagctgca agaagtaacc
    10741 ttgagcaata taactgcttt tacagccggt tcagcattta acctttctct tgaatggtat
    10801 atagatggaa aaaaaacagt ttatgaagta atgaatcctt tcatacttga gcctggcaaa
    10861 agttgttcat tgcccatcac agtacctaca acgattcatg gtgctcatac ggttgctgtt
    10921 tcgctatctg tttataaaaa tgatgagctt tatggacagc aacagctctt tcttaaaaaa
    10981 gaaaaaatga gattgccaag aactgctcat cataatgatg caccacaaat ttcagtaaaa
    11041 ggcacagagc tgataatcaa aggagaatcc tttatttata tatatcaatt agcaaaagct
    11101 gcgttcactt ctgtaaagat caatcaaaag gaacttttgg aacgtcctac tcaattttca
    11161 atttggcgtg caccaacgga taatgatcgt aacttagtaa acaaatggaa agcagctgga
    11221 tatgctgaaa tgtctttaga aatcagaaaa aaagactgga aattcgtaga tgatcatctc
    11281 ctgatcgaaa cgtcttatcg aggagttatt ccaggattac agccaatttt tacaatgcac
    11341 atacagttga aaataaatgg tgcaggcgta atcaaccaaa aagtatcagt ggagaaaaat
    11401 ccgatttttc cagatttccc tcgctttggg atggactggc cgttgaatga tactttttcg
    11461 aaggtttctt attgtggcta tgggccgtat gaaagttatc ctgataagca ctatgctgcg
    11521 atgtttggta tttatgagat ggagattgag gaatttgatc agccatatat caaaccacaa
    11581 gaatatggta accgctggca atgtgattgg gtatcaatca aaaatcatca aggatctacc
    11641 atgacggttt atggaaactc taatttttct gctctgcctt atagtcaagc tcaattaacc
    11701 gaaaagtcac accattatga attaataaaa gaaaatagaa cttggttcaa tttaagttat
    11761 aaacaaaatg gtatcggctc acacagttgc ggtccttatt tagaagatcg tttccgtttt
    11821 atggaagata cttttgactg gaatatagtg attactttca aaggagaaaa tagatgaaag
    11881 aaacaaagat caatcaagtc aaaaaaaaat tatctcgtta tcaagaagtt gtttatcgaa
    11941 accattgctt aaaatggtca aaaaataagc tgaatgttcg ttttaatgga ttattttatc
    12001 gtttcgaaca gttagaagaa gtctggaaac cggtaacgaa tttccaatca tgtcctgtac
    12061 agctcataaa tgatccaaaa gaaacatacg atttatgtat aacacacctt tataaccagc
    12121 atttgaaaaa tgacggattt tatttaaagg ttactaatga caatcaactt acgattgaat
    12181 cagcaaacct tcgagggttt caatatgcta tggaagcctt attagagagt tttttttcgg
    12241 taggagatca attattatta ccggaattga ttctgaaaca tgaaccatca gtgaaaattc
    12301 gaggaatcat tgaagggttt tatggtatcc cctggacaca tgaaatgcgc ctctctcttt
    12361 tttcatatat gaaagataac caattgaata cttttatgta tgcccctaaa gatgatgaat
    12421 tattacgtaa aaaatggcgt gaactctacg atgcgcaaga attagacaaa tttaaggagc
    12481 ttttatctgc tgctgaggct agcaatatcg atttttggta cttaattagt cctggaaatg
    12541 atattgatat tacgtgtgaa gaagacattc aagttcttct gaaaaagtta gaacaactga
    12601 ttgagcttgg cgtatttcaa tttggtctat taatggatga tattgactat caattaaaag
    12661 gtgctgctaa acgccgtttt cgagagccag cattcgctca tgcctattta gtgaatcgag
    12721 tagaggaata tcttagcact cggttgtcca atcatgaatt agtcatttgt cctacagaat
    12781 atgataatcg tcatggttct cgctatttag caacgttaag tcaagaaata ccagaacaat
    12841 taccgttctt ttggactggc ccaagcacgt tagcggcgtc aatttctaca gaagagctgc
    12901 aggaaatggc ttctgtctat caacggccga tgctgatttg ggataatatt ccggtaaatg
    12961 attatttaga ggataaagaa ctattgttca tgagtccata tgagaatcga acaccgaatc
    13021 tttctaagga gagataccag gttacaggag tagtttcgaa tccaatggct caattagaag
    13081 cttcaaagtt tacgatcaat agtatggcta attacttatg gaactgtgag cgctttgatc
    13141 ctttggaaac ttggacgtca gtcgttgaaa aagtagttgg aagtaaacta caaccagctt
    13201 atcttacctt aaccaatgct tttccaaatc attacacaag cagtctgctt tcagatgaag
    13261 aattactgct agccaaagac ccagaatggg tcacaaaaga aatggctgct ttagtccaag
    13321 cagtaaaatg gatccagcaa gaacaacata catctagatt gagaacagaa ttggagcctt
    13381 ggttacaagc aatcacagaa agttggactt tctggcaaga atggcaatta aaaaaagatc
    13441 caaaagaagc agaagaatgg ttggctaaga aaaaaacaca ccgcatagga cgtgatttag
    13501 taactgccca tttagagcaa attatcaaaa gttagatatc ttaaaaaata aaaagcaaga
    13561 aaaaggagaa caaaatggtc aagagattaa ttagtgcaaa ctacagtgat gtcaagaaaa
    13621 tgacgtcaaa agagttgaag caatccatca aagcgagtga aggacgggtg attgtttgtg
    13681 aaacggttgc taatactctt ccacaatctg gagaaattac gaatgcagaa gttgcgtcag
    13741 catttggtgc agatttgatt cttttaaatg gtttcgattg ttatcgtcct gcagtttttg
    13801 gactaccaaa tgtgacgatt gagaaggttt ttgatctaca gcaaacgatt gaaaacccga
    13861 ttcctaaatt aaaagaacta gtcggtcgtc ctgtgggaat taatttagaa cccattgccc
    13921 ctaaaacaaa tatgatgagt gagaaagtag aaatcagcca aggaagagca agctctgttg
    13981 aaacgataca aaaagcagaa gaactaggag tcgattttat ttgctttacc ggtaatccag
    14041 gcactggagt aaccaattta gaaattacta aatccgtaaa aatggcaaaa aagtattttt
    14101 cgggattgat tattgctggg aaaatgcata gcgccggctc agaagagcca gttgtgaata
    14161 aagaggcgat tatttcttat gcggaagcag gcgcagatat tttactagtt ccttcagtag
    14221 ggtctatccc aggcttttta gagcaagacc taattgaagc ggttcggttg gcaaaaaaat
    14281 atgatttgtt aacgatgtct gcaatcggta ctagtcagga aagtgcccga ccagaaacat
    14341 tgcggcaatt agccattatg aataaaagtt gtggtgttga tttacaacat attggagatg
    14401 ctggatacgg gggattggca ccagcagaaa atattttcga aacctcggtt gcaattagag
    14461 gaatgcgaca taccatcaac tgcgttagcc gctcgatcaa tcgctaacaa aattaaataa
    14521 aaaatggtta aattgattat ttaagtggga acatacttga gatatcagct aacttctgtc
    14581 attttaaaaa aagggactgt gacagaagtg aaaatagaca aaaaatatcc gaacaagaga
    14641 ctaggatagc agaaaaacta tcgttttgca acgaggacca actggaacgt aggagcaatt
    14701 ctcttattgt tcggatattt cgcttgttca aggacttatg tctgtagtgc ccttttttgg
    14761 taggaaaaat ggtagggaac catatcattt ttaatgaaaa tcaagcattt caaaagttga
    14821 aaaacgttga tttatcggca ttccccatcc atattatatt tacgtcttat tcccactcca
    14881 ctgttgcagg tggtttgctg gtaatatcat acacgatacg gttaacgtgt gcgacttcat
    14941 ttacgatacg gacactgatt ttttgcaaga cttcccaagg gatacgggca aagtcagcgg
    15001 tcatgccgtc aatagaagtg acagcacgga tacctacagt gtagtcatac gtacggccat
    15061 ctcccataac cccaacagag cgaatgcctg gtaggacggt gaagtattgc cagatgtcgc
    15121 gatctaaacc ggcattggcg atttcttcgc gcaagatagc gtctgattca cggacgattt
    15181 ctaatttttc ttctgtcaat tcaccaagga cacgaatacc taagcctggt ccagggaatg
    15241 gttggcgcca aacgatgctg tcaggcatgc ctaattgggt acctaattca cgtacttcgt
    15301 ctttgaacaa tgtgttcaat ggctcgatca gcttgaattg catgtcttca ggtaatccac
    15361 ctacattgtg atgtgatttg atggtttggg cagtttcagt tcctgattcg atcacatcgg
    15421 tataaagggt tccttgtgca aggaaagaaa cgccttcttc accggcaagt ttggttgctt
    15481 catcatcgaa gacatataca aattcatttc caatgatttt acgtttttct tctggatcag
    15541 acacgccagc aagttttgat aagaaacgtt ctttggcatc gacttttata atgttcaagc
    15601 caaattttcc gccaagactt tccataactt gttctgcttc acctttacgc aacaatacgt
    15661 gatcaacgaa gatacatgtt aattgatcgc cgatcgcttt ttgtaaaaga acaccaacaa
    15721 cagaggaatc tactccgcct gaaaggccta ataaaacttt tttgtcaccg acttgttcac
    15781 gaatttttgc gatctccatg tcgatgaagt tatccattgt ccagtcacca gtacattggc
    15841 agacatctag tgtaaaatgg cgcaacaagt catttccata ttcggaatgg cgaacttctg
    15901 catggaattg gattccgtac attttgcgtt ctgcattttg gatcgatgcg atggggcaat
    15961 ctttgctggt agcaacgaca tcgaaatcag tcggtgcttg ggtaactagg tcaccatgac
    16021 tcatccaaac ggtttgtttt tcaggagtgt tttggaaaag ggccgcttct gcagaagtga
    16081 tttccaattc tgcttttccg tattcacggt ttttggctgg tttaactttt ccgcctaatt
    16141 tataagtaat caactgcata ccgtaacaga ttcctaaaac tgggatcccc aaatcaaaaa
    16201 tcttttcatc aataccaaag gccttctcat cataaacact gtttggtccg ccagaaagga
    16261 tgattccttt agggttcatt gcctttactt cttctgcggt aatgcggtgg ctcatcaact
    16321 ctgagaaaac accgaactca cgaatacggc gagtgatcag ttggttatac tgactaccgt
    16381 aatcaagtac gataattttt ggctcttcgt caaatcgtgt tggtgaagac aaatttgaat
    16441 aaaacttagt ccgatatgcg gcgcgttctg tgcgccgcat atttttttag ttttcaaaga
    16501 tcagaccttg ttgtaaatag atccgtgccc gaaagttata aaagttgcga taaccaaacg
    16561 caattcgttt aatcagcttg atcttgttat tcagcccctc agtgacgccg tttgagtggg
    16621 acaccttaaa ggcatttgaa atacccgatt ggtagcgatg gaagatcgtg aatttctttt
    16681 taaacgactg aggtaacgta gatgaaattg ttttaagggt ttcttgaaag ccttccgtac
    16741 ctcgtttaac gaaataatag cgtaataatt gacaaaaatg atacgcagtt cgcaattctt
    16801 cgttgtagct taacagctca tcaacgattt ctgtttgact aattggtcgt ttaaacagtc
    16861 gatgataatg ccgtttgagt ggctccaatg tcgtggaatc tttgagtaag agtttccaat
    16921 atcgcttgag ccgacggtac ttcttctgat tttcagagtg tgaggttcga aaacgattca
    16981 tgatctggac acgtaattga ttgaagctgc gattgatgtg ttggacaata tgaaagcggt
    17041 cagttacgat ctccgcattt ggaaagactg ttttaagcaa ctgacaatag ctggcattca
    17101 tgtccatcac tag
//
LOCUS       DADVXB010000057        16763 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.058, whole genome shotgun sequence.
ACCESSION   DADVXB010000057 DADVXB010000000
VERSION     DADVXB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.058"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(126..1631)
                     /locus_tag="KB902_001459"
     CDS             complement(126..1631)
                     /locus_tag="KB902_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6808294.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLFENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1628..2314)
                     /locus_tag="KB902_001460"
     CDS             complement(1628..2314)
                     /locus_tag="KB902_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808295.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2507..3928)
                     /gene="gndA"
                     /locus_tag="KB902_001461"
     CDS             complement(2507..3928)
                     /gene="gndA"
                     /locus_tag="KB902_001461"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBB6808296.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4098..4277)
                     /gene="rpmF"
                     /locus_tag="KB902_001462"
     CDS             complement(4098..4277)
                     /gene="rpmF"
                     /locus_tag="KB902_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6808297.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4335..4904)
                     /locus_tag="KB902_001463"
     CDS             complement(4335..4904)
                     /locus_tag="KB902_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBB6808298.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5090..5992
                     /locus_tag="KB902_001464"
     CDS             5090..5992
                     /locus_tag="KB902_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6808299.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6027..7811)
                     /gene="pyk"
                     /locus_tag="KB902_001465"
     CDS             complement(6027..7811)
                     /gene="pyk"
                     /locus_tag="KB902_001465"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBB6808300.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(7885..8847)
                     /gene="pfkA"
                     /locus_tag="KB902_001466"
     CDS             complement(7885..8847)
                     /gene="pfkA"
                     /locus_tag="KB902_001466"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBB6808301.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9015..12329)
                     /gene="dnaE"
                     /locus_tag="KB902_001467"
     CDS             complement(9015..12329)
                     /gene="dnaE"
                     /locus_tag="KB902_001467"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBB6808302.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12560..12745
                     /locus_tag="KB902_001468"
     CDS             12560..12745
                     /locus_tag="KB902_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBB6808303.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(12807..14003)
                     /locus_tag="KB902_001469"
     CDS             complement(12807..14003)
                     /locus_tag="KB902_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6808304.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14173..15609)
                     /locus_tag="KB902_001470"
     CDS             complement(14173..15609)
                     /locus_tag="KB902_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6808305.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            15902..16711
                     /locus_tag="KB902_001471"
     CDS             15902..16711
                     /locus_tag="KB902_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6808306.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         4907 a         3527 c         2944 g         5385 t
ORIGIN      
        1 acggatgtta ttctatttaa ttgttcgcta gtttttttat aatgacatcc ctgaatttct
       61 cacttgcttg tattttgtac cttattcttt gttggatata taaaaaaaca agtaaagcac
      121 atgctttact tgtcttctgc ctttgcgata ggaataaaga ttctaaaaat tgtcccttgc
      181 cctactacac tttctgctaa gatacgtcct ttatagtttt caaacagttg tttagcgata
      241 gacaacccca gaccatttcc acccttcgtt ctagctcttg ctttatccac tcgataaaaa
      301 cgattgaaga tcttattaag gtcttctttg ggtattcctt cgccaaagtc ctgaatcgcg
      361 atctcaaatt cattcagagt ggaagaaata gagatatgga cttcttttcg tgtagttgaa
      421 tactttactg cgttatccaa tatgataatg attaattgtt caaagtgatt acgataaatt
      481 tgcagggtca cttcttttgt caaatcatca tctaaagtga tcacatagtc tggatataat
      541 atcttgaaat tattataaac ttgataggtg acttcttttc ctttagttgt ttcattcgca
      601 taatgaacat ctacttgttc tgctcttgat aagtctagca tctcttgaac taagcttttc
      661 atacggctga tttcttgcat gctggcgctt aatgattctt ctaatatctc aggatcatct
      721 ttcccccaac gatttagcag actaagatgc ccttcaataa ttgcaacagg tgtccttaac
      781 tcatgagata cgtcttccac gaattgctct tgttgttcaa tatacaaacg catacggtca
      841 agcatctcat tgaatatttc agctaaatct gccaattcat catttgtgtc gatttcaggc
      901 atgtggatat ctgattgcgg atctttacgt atagtatcca ttgtatctct gagtaccttg
      961 agtggtttta agaaataaga agataaaaag aaacctaaaa tactacttaa gatcaaagaa
     1021 acaacttcta aaacaataag agtcaataat agcttatttc gaatatcata gaaagaagat
     1081 aattcataga agctttgcgc atagccgatc ttttctcttg tacctttaga atatataggc
     1141 tggatagata aaaagccagt ttttccttct agtgtaacga tcgttggaac tttacgtgta
     1201 gtctgaatca ggtttcgact gttttcatgg gttttaaaaa tcaagttctc gtccaaatca
     1261 taaacataaa gatccattga tggctgccct agctcagcta taaaggaatc gatcttcatt
     1321 aagtttcctt cgaccagtga agtatgatct acgacctcat ctccgtcatt tgtcgctttc
     1381 gtcagattac gatacgtatt tactaatgtc agttcttcat ccgagttagc caaacgagaa
     1441 gctacttctg aaatcgtacg ctctacattg tttctttctt ttgccacaat cagattgata
     1501 gatgatttat aggtaatgac agcgaaaatt gtaaacacaa cgaatatgaa gaaagaactc
     1561 gcaaaggccc acttgattgt caaggagggc cctttcagtt ctcttttttc cgattttttc
     1621 ggctttatca cgagcgcatc acataacctg ttccgcgtac agtttggata tagctttcct
     1681 ccccgggaac gtcaattttg ttgcgaagat aacgaatata tacgtccact acgtttgttt
     1741 caacttctgt ttcgtatccc cacactttat ttagtaaaac gtcacgtgct aataccacgt
     1801 tcacgttttc cattaaagta agcagcaact cgtattctct ttttgttagt tcaattactt
     1861 catttccgcg acgtacgaca cggttttctt tttcgatagt caaatcgcga taagtaatag
     1921 tagtttgttt agccacattt ttatcgcctt caatatcgat tcgacgcaac aatgcacgaa
     1981 gacgtgctaa taattcttcg atagcaaatg gtttgacgat gtagtcatct gctccgtggt
     2041 caagtccaga tacacgatcg atcacagaat ctcttgcagt catcataatg attggtgtat
     2101 ttttgacttg gcgtacacgt ctgcagactt ctaaaccgtt caattctggg agcatcagat
     2161 ccaacaatat ggcatcccac tcattattta atgccgcatc taaaccagtt cggccgttgt
     2221 agtggacttc tgcgttatac ccttcatgct tcaactctag ctcgacaaat cgtgccaagt
     2281 tcttttcatc ttcaatgatt agaatattgc tcatttatta ttttatcctt tctattctac
     2341 tggcttttta aaaactctat cattataccg ataatatgct taaaaatcta tagtcatttt
     2401 atcatggata gcaattttaa aaaagagctg aagtctactc ataacaatcg acttcagctc
     2461 tttcgtcctc tttttatttt ctcatttcct aacagccgaa agactattat tcttcatggt
     2521 accatgagta atggaagatt ccttctttgt cgacacgctc ataggtatgt gcgccaaagt
     2581 aatcgcgttg ggcttggatt atatttgcag gcagacgttc tgctctgtat gaatcgaagt
     2641 aagcgatggc tgatgagaaa gtcggtacag gtacgccagc ttggacagcc aaggcaacga
     2701 cgtctctgac tgattgctga tattttttcg tgatttcaac gaagtaatca tctagcaata
     2761 aattttcgat ctcaggattt ttgtcatagg catccgtaat tttttgcaag aatcgagctc
     2821 ggatgataca tccagcgcgc cagatttttg cgatttcacc aaatggcaag tcccaatcaa
     2881 attcttttga agcgacacgt aattgagcaa atccttgggc ataactcatg attttactga
     2941 aatacaacgc ttctcggatt ttttcgacca attctttttt gtctcccgtg aactcaaaat
     3001 cgttcgtacg agacaaaatc ttgcttgctt gtacgcgttc ttctttataa gcagaaatat
     3061 agcgggcaaa tacagattca gtgatcaatg gaagtggcac acctaagtca agcgcgcttt
     3121 ggcttgtcca tttacctgtt cctttattcc cagctgcatc aaggatcaca tctactactg
     3181 gtttacctgt tccttcatcg tctttacgtg tcagaatgtc agcagtgatt tctatcaaat
     3241 agctgtctaa ttcgccttga ttccattctt taaagatatc agccatttct tctactgaaa
     3301 ggtttaaaat attcttcatt aagtcataag attcagcaat cagttgcata tctccatact
     3361 caataccgtt gtgtaccatt ttcacataat gtccggctcc atttgggcca atatatgtga
     3421 cacatggtgc tccgtcttct gcttttgcag aaatttgctc taagattggt gcaactagcg
     3481 cataggcttc tttttgtcca ccaggcatga ttgaaggtcc ttttaaagct ccttcttcac
     3541 caccggaaac gcctgtaccg ataaagttga tgccagagtt ggctaactct tcattacgac
     3601 gcatcgtatc tttaaagaat gtatttcctc cgtcaatcaa aatatcgcct ttatcaaggt
     3661 gaggaagtaa ctcttggatt gttgcatctg ttgccggtcc tgctttgacc attagcaaga
     3721 tccgacgtgg tttctcgata gattctacaa attcttcgat tgtatatgtt gctttgaaat
     3781 ttttatctgg gtgttcttct actacagcgg ttgttttagc ccctgtacga ttgaataaag
     3841 ccactgaata gccgcggctt tctatgttca aggctagatt tttacccata acggccatac
     3901 cgacaacgcc gatttgttgt tttgacatat gaactcctcc tacatacggg atttctccct
     3961 aatctcttac attatagctt aacacggcta cattgcaaac taaagaacaa catatttttt
     4021 atttaccgac tacaaaaaaa taaacctcaa ggctccatgg ttagccttga ggttttacat
     4081 tttctaatta aaatgtatta agcttctttt gacattacgt ccttaccatc atagtaacca
     4141 caatttgcac atacgtgatg gctttttttc atttcaccac agtttggaca ttcgtttaac
     4201 cctttgattg tcaatttgta gtgtgtacga cgttttgctt ttttagcttt tgatgttctt
     4261 ctagctggta ctgccatttt gctacacctc cttgtaaagt cttgtatcta aattagacac
     4321 aatatattcc aatcttactt gttatcgtcg tcttttgatt tagaatcaaa aagttcagat
     4381 agttttgcaa gacgaggatc aattttattc tcggcttctt ccatttttct gcgctggtat
     4441 tcttcttcgg aaacaacttc ccaatcattg ccttttggaa gttctgttgc tgcttcctct
     4501 tcttttgtca atacccgcat tggaatcgcc aataagatgt tgtcttcaat cgactctgct
     4561 aaattcaata atggaccttc aattagcaaa atctcatctg cagacatttg ttcatctcta
     4621 ctttggaatt gttcttctgt catgaatact tcgtctacag aaaaatccat gggcagttca
     4681 acaggttcta gtgaacgtgt tgaaggaact gtcaaagtcg tctgcacagt gtaatgaacg
     4741 atatagcctt tcttatcaac tgagaccaaa ccttcgactt ccactggcgc aacatcaagt
     4801 attaaattgt ctcgcttcat gagagcggct ttcaagtcga gcgtctcatg aaaagttaac
     4861 ggtgtctcct ggtattttct caattccaat aaagaccatt tcatttttca tcactcctaa
     4921 gcaacaaaag caattataca gggcaaaaag catgttgtca atgaaatttt cttgacacct
     4981 tgcagttcat aaaaaaacag aaaaatcttt attagaaagc ctctgtttgc tatcatcctc
     5041 agaatcattt acaataatca ttattccatt aaaggagcgg atgatcttca tgaacacgaa
     5101 agatatcgaa tactatgtcc aaatcgtcaa acaaaaaaat tttacgaaag tggctaatta
     5161 tttccgtgtg agccaaccta ctattacata tgcattacaa cgtcttgaaa aagagtttga
     5221 caccgtactt attacaagag atcgatcgca tcacgaattg atcgtcacgc cttctggaaa
     5281 gcagctgttt ctccatgcac aaaccattct ccaagagatt tctactgcaa gagctgaaat
     5341 cactcagttg caaaagaaaa agcttcgttt tggcatgcct cctattatcg gcaatgaata
     5401 ctttcctaaa ctgtcaagtt actttatcaa gcatgaattg atgaatcaaa ttgagattac
     5461 cgatggaggc tctcgggact tatacgggat gatccgacaa gggaggatcg atttagctgt
     5521 attaggctca acacagccaa tcgtggatca atatttagaa acagagttac ttttggacaa
     5581 acgtttcatg atcgtcgtgc cacctacaca tcctctttcc aagcaggata ctgtctcttt
     5641 caaagatata gcagatgaac agtttgtact attgaacgaa cattatgtcc accccgcagc
     5701 attcactaag ctttctaaac aaacacatac tcatccaaaa gttgtttatc aaagcaatga
     5761 cttgacgatt ttaaagagta tggtccgaga aaatgtgggt atcggttttt tggcagagat
     5821 tgctgtccat cctgaagatc atttagtttg cctccctctt tcagatgaag ttcagcctcg
     5881 cttcttgatt tcattggcaa aacgaacaca gcagatcgtc acgcctcttc aagaacaagt
     5941 agtccaagtt atccatgaat tcgttacagc acaaaaaaac agctcttcgt aaaagaagag
     6001 ctgtttttat tttttattaa gctaaattag atagctgttg tttcgccacg gtaaacgatg
     6061 ccgcgacgtg aatcaacggt aatcaattca ccttctgtaa ttgttgttgt tgcgccttta
     6121 gcaccaacga ttacaggaat atcttgtgca attcctacaa ctgcagcgtg agaagtcaat
     6181 ccgccttctt caacgataac agcagctgct ttttcgattg caggcatata ttctttgtca
     6241 gttgatggta caactagaac cattccgtct tttgcttttt ttacagcttc ttcagcagat
     6301 gaagcaataa ctgcatttgc aacgacagat ttttgtccaa cgccttgagc ttctaataat
     6361 ttagaaccaa tcatttgaat tttcatcacg ttagttgttc cgcgttcacc aactggtaca
     6421 ccagcagtga tcaagattaa atcgccttct gatgcgaaac ctaattcaac agctttttta
     6481 gctgctagtt caaacatttc atcagttgtt gatggttttt cagcaactgt tgggtaaacg
     6541 ccccagttta acatcaaacc acgttttgtg cgttcgtcaa aagtaacagc caagatatct
     6601 gcatctggac gatattttga aatcattttt gcagtgtatc ctgattcagt tgcagcaacg
     6661 attgttttca cgcctagatt ttttgcagca cgagctacag ataaaccgat tgtttcagtt
     6721 acatctgttt tatcgaattc gttcaattgg aatgtaccta attctgataa tgcattttca
     6781 gcttcttggt cgatacgtgc cattgttgaa acagcttcaa ctgggtagtc cccgtttgca
     6841 gattcaccag atagcattgt tgcatctgtg ccatcaaata cagcgttagc aacgtcagaa
     6901 gcttccgcac gtgttggacg tgggttttct tgcattgatt ctaacatttg tgtagcagtg
     6961 ataactggga taccagcagc attacatttt ttgataatgc gtttttgaac cattggtact
     7021 agttcagctg ggatttcaac acccatatct ccgcgggcaa tcataacacc gtcagaaact
     7081 ttgatgattt cgtcaatgtt gtcgatacct tcttgagatt cgattttagg gaagatttga
     7141 acatgagtca tgtctttttc ttctaagatt tcgcggatat ctagaacgtc ttgtgcttta
     7201 cgtacaaaac ttgcagcgat aaagtcgata tcgttgtcta aaccaaaacg aatatcgtca
     7261 gcatcttttg gagtaatacc tggcaaacta atagaaacgc ctggtgcatt taccccttta
     7321 cgtgatccta gcatacctgc atttttaact tctacgacta attcacggtt tgcttcgtct
     7381 ttttcaatga tttgcatatc gatcaaacca tcatcaaata aaatgtgtcc gccaacgtga
     7441 acatcgtcaa ataatcctgg gtaagtaacc gcgatttttt cttttgaacc tacatgttca
     7501 ggatccatag agatgcgtgt ttgatctcct acttcaaatt tgatgtatcc tgcacgacca
     7561 aaatcagctt ctgttgtgcc ttgaacagtt gtacggattt cagctccttt tgtatctaaa
     7621 agaataccga catcttttcc tgtcttttta actgcttcac ggaccatagt catacgtgat
     7681 aattgttctt catggtcacc atgagaaaaa ttaaagcgga agacatttgc cccagattca
     7741 atcaattgag aaataatttc tactgagtta cttgctggtc ctaatgtact aacgattttg
     7801 gtttttttca tttaaaaaac tctcccattc aattttgttt atttaaagct gtacacagct
     7861 taaatagctt ggtttctttc actcttaaaa tgaaagtgaa ttatttagat catatagtga
     7921 taagtctggt ttatgtttgt tgttttcaag tgtatcaatg atgtcagacg caacgatttc
     7981 gttgtcatgg ataccgacac ataatccacc ttttccttct tgaagcaatt cgacagcgta
     8041 agcaccgaat ttacttgcca acacgcggtc gcgtgcgctt ggtgctccac cacggacaac
     8101 gtgtcccaag atagatacac gtgtatgata gtcaccaaat tctgaaagtt tctcagcgaa
     8161 ttcatttccg cccattacac cttcagccaa gatgatcaag caatgtttct tcccgcgatc
     8221 gcggccttct tggatttttt tagcaactga agccatatca aaatcatgtt ctgggatgat
     8281 gatttcatcc gctccgccag ccacacctga ccataaagcg atgtctcctg cattgcgtcc
     8341 cattacttcg ataacgaatg tacgaacatg agaagtcgct gtgtcacgaa tacggtcaat
     8401 tgattctagt actgtattga ttgctgtatc aaaaccgatt gtgaaatcag tcccaggaat
     8461 atcattatcg attgttccag gaatacctac tgctgggaaa ccgcgttttg tcaaagccat
     8521 tgcgccatga taagagccgt ctcctccgat aaccactaga ccttcgattc cgaatttttt
     8581 caattgttcg attcctttta attgaccttc ttcagttgca aattctggat aacgtgcaga
     8641 atacaagaat gtaccaccac gttggatctt gtcacctaca tctgccacat caagacgacg
     8701 aatatctcca gcaactaaac cggcaaaacc ataattgatc ccgtatactt ccagtccttc
     8761 gtaaatacct ttacgaacaa cggcacgaac agctgcattc attccaggtg cgtctccgcc
     8821 actggtcaaa attccgatgc gtttcataat aaacattcac ctcattaaaa tactttatcc
     8881 taagtatgac ttaggtttac aaccattttt gcgttaacca cgactaacat tctaacatta
     8941 tttttctcac ttgtcttgat ttacggataa aaaaatgaaa aaaaatgaaa gcaagtagta
     9001 ttttttaccg taagttattt gaaaaccaca ttatcttcgc caagcagata aataagttgc
     9061 cgctttatac tcttgctgtc atccacccaa taagcatctg acagaactac ttttcgttgc
     9121 gttttttcgt gatacataac tactggtata tatcctgggt gtttctgaaa aatcacttgt
     9181 aattgtttca ttatctcggg atcttcccgt tcttctgtaa tacgcaaata gcaagtttgt
     9241 gaaggatact gggcttctaa ctggttagga tcagcaaagc tttctccaat tagttgcagt
     9301 tcctgattat atttgctgat ttcgctccgc ccttgaacaa agatcactcg atcaacggca
     9361 aacaaattac gatatttacg ataaagagtt ggaaaaactg tgacagaaat ttctccacta
     9421 ctgtcggttc cttcaacaaa ggccatcagt tctccttttt ttgtccgaat ttctctaact
     9481 tccttgatca tcactaataa attgactggt tgattaggga cgatatctgt aatcagctga
     9541 acttgtttag ctaaacgaag acgatcaaac ccttctgcag gatgacctga caaataaata
     9601 cctaagtact cctcttccag cttcaagcgt tcttctagtg tatagtcagc gacttcttct
     9661 tcttttaatg ccatgattcc cagcaagtca agacttccac cactgtaaac gatattttgg
     9721 atttttcctt cgagatcaag catcaattgt ttcctgttag gagataattc atcaaaaact
     9781 cctactgctg tcagtgattg cagtaactct aatttcagcc aacgcttatc gatccgtatg
     9841 aggaattgat ccactgactg gaacgggcca ttttgttttc tttcgtttaa tatatcttct
     9901 acaaaatcac gccgaatacc ttttatcgct gtcagtccga atctgatttc ttccttattg
     9961 accaactcaa aactggaatt actttgatta atggacggcg aggaaagttt gagtttattt
    10021 ttacgtgctt ctgcaatata ttctttcaat tttgatgtgt tatgccgaac agaattcatc
    10081 aggctggtaa agaaagcacc tggatgatgg gcttttagat acgccatttg gaatcccacg
    10141 aatgaataag caaatgcatg tgaccgattg aatccatagt ttgcaaattt ttcgatatat
    10201 tcatatacgg tcgctgctgt tttttccgaa tatccctgtt gtaatgctcc tgatacaaaa
    10261 tgcgactttt cttcatctaa tacgtctttt ttctttttac tcactgcccg tcgcagaata
    10321 tctgactgcc ctaatgtaaa tccagccata gtcgaggcga tctgcatgat ttgttcctga
    10381 tagacgatca ctccatatgt gtttttcaaa atcgggatca gtgaatcatc tgggtagcga
    10441 atggcttctt ttcctttctt cctggcaatg aaggtatcta tattttgcat agggcctggt
    10501 cgatacaatg cattgactgc ggcaatatct tcgatgtttt ctggatctaa tcttcgtaaa
    10561 acgttccgga taccagcaga ttcaaattga aatactcctg aggtttcgcc tcgttgaaac
    10621 aagagcagcg tttttgcatc atttagcggg atctctttta atcggatctc atacccttct
    10681 actcgcttaa cagctttcaa agtaaaatca ataatcgata agttgcgtag tcctaaaaag
    10741 tccattttca aaagaccgat tgcttctacc tcattcatcg tatactgggt cagaaaagct
    10801 tcatcagaac cgcgttggag cggaactagt tcaagtagat tcttatcgct gataactaca
    10861 cctgctgcgt gagtcgaaac atgtcttggc aatccttcta aaatcactgc agttttgaat
    10921 aaaagttggt ttttttcgct tgcctgaact aattctacta attgatgcga agttttataa
    10981 gcttgggtca atgtgatttt caattgattg ggtattgctt ttgaccagcg gtttgcttca
    11041 ctttgcgata aaccaaacac tctagctgca tctctaagaa ccatttttgc tgccattgtg
    11101 ccaaatgttg cgatttgtgc catatgatat tgtccatact tttctcgaac ataattcaat
    11161 acttcttcac gtcgattgtc aggaatatcc aaatcgatat ctggcatcgt aaagcgttcg
    11221 gggtttaaaa agcgttcgaa cagcaaatca tattctaatg gatccacatc tgtgatttct
    11281 aacacatagg ctactaatga acccgcagca gaaccacgac ctgcaccggt aacgattttg
    11341 tttctatgag caaaagccat tacatcccat acgatcaaga aataatcatc gaatcccatt
    11401 tgatggatga cagataactc gtagtccaaa cgttcttggt attcctttgt atagtcagtg
    11461 attcggcgtt ccacttgcga atagcataac tctcttaaat attctccagc ttgttttcca
    11521 ttaggaactg gataatgcgg aagtaatttc tgatggaact ggaattcaaa tgaaatcgat
    11581 tcagctaaac gctgggcgcc tattacagct tgggaaagac ccgctttttc gaatcgtttg
    11641 atcatttctt gttctgaaag aagatagaca tttgctgtta gtggtaaaga tgcagataaa
    11701 ttttctaaag gtatttggct tccctctttg atatgtttca tcacttcaag tgcaaaaagt
    11761 tcttcttgtt gtaaactagc gatgggatgt aatgcacaaa gcgaataatt ttcttttatc
    11821 acatactgat accattcagg caattgatca ggcgtgtttt ctgtcaagcc gatataaaaa
    11881 tttctagtaa aaacattttc aagtaaaaac tgccaatgac cgaaaaagtt atcctcttta
    11941 ttgaaagcct cagaaacaga atgatttgcc ggaacaacaa acgctagatg gtcggtttct
    12001 gtcatttctg caagttccaa tttttcttgg atcatttttc ggctggaaag tttcatcagc
    12061 tgctgataac ctatttcatc ttttgcgtac gcaagcaagc cataattttt ttcttcataa
    12121 gtataactaa gatgtaatcc aatgattggc tgtactcctt cttctacaca aatacgatag
    12181 aattcaggtg caccgtataa gacatcttta tccgttatgg ctaatgaagt gtagccttgt
    12241 ttttttgctt cttgtacata ttctcgaata cgtatcgtac tttgtaaaag agaataagaa
    12301 gtaattgtat aaagttgtgg gaaaaacatc ttgcattccg cctttttttt cgttaaaatt
    12361 cactagcgtt aaaaggtttg atccttttac tttcattaag atagcaggcg ctgaagttga
    12421 ttattccact tcatttgctt gcttgtaatc tgtaggaatg agttctttcg caagaactca
    12481 aattttattg agatttggtc tcgtttcttt acattcaaag aaaatctggt aaaattaaga
    12541 tagaaaagag gtgttcttta tgcgatatat cgttacatta ttctgggctg tcgttctagg
    12601 tcaagtagtc ggttatattg gtgctgcatt aacaagcgga acatatgatt ttactttgac
    12661 aacaatcatt tcattcattg cgggtgtcat tatccttttg attggtgcag ttgcgccaag
    12721 aaaagaaacc tctgcccatt cgtaaaaaaa cagccaagag cttgagattt ctcaagctct
    12781 tttttatttt ctactcctca ccaccattat aatctgctgc gaagaacttt acgaaagttg
    12841 aataaagaaa gaagaatatt tgacagaaca aacaaacttg tcacaataaa aacagcactg
    12901 taattataag catgcgcgac tgtcgatcct agcatgggac ctaaaacttg tccaaagttg
    12961 ctaaacatct gattgtagct atagattcgg ctgactcctt cttgaggcgt aatcttactg
    13021 atcagtgtat tgacagaagg catcaaagcg ccagttgaaa agcctaaaat aaagcgaagt
    13081 atacctaatt ggagcggtgt agtgacgaat gccataggta aataacagca aaatgataaa
    13141 atgagtcctc caattagaac tttttgattc ccaatcttat cccctagttt tcctagtttc
    13201 ggtgaagaaa agacagcgga aacaccagct atcgaaacaa tcaagccgct gacaaaaagg
    13261 atattttctg tacttccgct caattcacga atatataagg tcaaaatagg gctgatcgta
    13321 gtgattccta tctgtaaaat caaggtcgta atgaagagac cgatcaaaat agagagatga
    13381 tccatttttg aaaaaatttc tttggtgctt atcagatctt ttttctcgat tggatggaaa
    13441 tcttctttga ctaagaaaat ggtcaatacc gttgtgatca tcaacaaagc ccctgtgatc
    13501 aagaatacat tttccatacc aaaccactga gccagtgcac cgcccattga aggtccgatc
    13561 agatttccag caatcgctcc ggtagacaat gttcctaacg cccatccgct cttttctcta
    13621 ggtgcctgtg aagcaatcat cgctgtggca tttggaatat atccagacaa aatcccattc
    13681 caaaaccgca tgatcaaaag ccaatacgcg tttggtacaa aagccaaaga tcccattgtt
    13741 aatgtcatcc ctgctgctgc acggatcatc atgagttttc ggccttttcg atcagctaga
    13801 tttccccaga ttggtgcaac cacggcagat gcaaaagcag tcacagagat tgctagtccc
    13861 gaaaacaatt cgatttgatc ttttggtgtt cctagttgct caacataaac tggtatgaat
    13921 ggcataacta aactaatact tgcaccagtg aaaaaacagc caatccacgc aatcactaaa
    13981 ttttttctcc aattaatctc catctatcat ccctctttcg tctcttttat catacctatt
    14041 ttcgaataaa caagcaacga tctcgccagt aaaaagagaa aaatcccgca aaggtcattt
    14101 tatatgtaac gttcttttta tgtaaaacaa aaagagatca gaacaaatac tgttccaatc
    14161 ccttctcttt agttaaattg ttgctagaat gatgaagttg ataatgaata aaatatcaac
    14221 gatccacaaa gcaacagaaa cttgattgta ttttcctttg attactttca caattgtata
    14281 gaaaataaat cctgctgcaa tcccatagga aatgctatag cacaatccca taaagatcga
    14341 tgcaaagaag gccggtaaag cttcttccat atctagccat ttgatgtctg caaaagaagc
    14401 catcatcatt actccaacta aaatcaatgc tggcgcagtt gcttgatttg gtacaatggc
    14461 gatcagtgga gagaataaac tacttaatgc gaatagcact gccactacta ctgaagtcaa
    14521 accagtacgt ccaccggccc cgatcccagc tgcagattcg acataagttg ttgtattcga
    14581 tgtaccaaag atagccccca cagaagtagc gatcgcatcg gcaaatagtg ctttatccat
    14641 ttttgttttg aacccacgac catcttccaa cgcgatctcg tcttcttttg agaaaatacc
    14701 tgtgcggcgt cctgtaccga taaatgttcc gatcgtatcg aaagtatcag ataaactgaa
    14761 tgcgatgatc gtcatcaata cttgaggaat cttggaagaa tcactgaata aagattgcat
    14821 gccttcagaa ccaaatgctg caccgaaagt tgttcctaat tctttaaatg aattacctaa
    14881 cgaattcgtt tgccaatcaa tggaacttaa atcaacaaca cccataaaaa taccaaggac
    14941 tgtggtcgct acgataccga taagaatagc cccacggaca ttttttacaa ctaaaatggc
    15001 tgtcagtacc aaaccaatca cagccaataa gataggagcg ttgtcaaagt tggctaacgc
    15061 agggacgatt ccaccattta tcgtaacatt tgtcgctttt ccgccttcaa cgacagagct
    15121 cgaaatagct gactggtctg ctgaaaaaga taagaatcct gcatttttga ttccgacata
    15181 cgcaacgaaa ataccgatcc cgccaccaat cgcatgttga agactttcgg gaatcgcccg
    15241 aataatcatt tttcgaatat ttgtgacagt aataaaaata ttgattaatc cgcaaataaa
    15301 caccattgcc aaggcttgtt gccaagaata accaagccca aaaacgaccg taaaagtgaa
    15361 aaatgcgttc aatcccatac caggtgcctg agcatatggt acatttgcga acaatcccat
    15421 taccagcgta ccaataatcg atgcaatgat tgtcgctaga aatactgctt ggaagggcat
    15481 acctgatgct gacaaaatcg tcggatttac gaataagata taactcatgg caaagaatgt
    15541 cgttactccc gccattattt cagttgatac atttgtattg tttttcttta aaccgaaaaa
    15601 cttttccata aaaagttcca ctccctgaat ttttttctga tggaaaacta taataataaa
    15661 aaataagtaa aatagggcaa atccatcgaa caatttcaaa ttatatagac gtttcattcg
    15721 cttttcaacg tttttttaac aaaaaaagcg aaaataatac ttaacgttcg tgtttagctt
    15781 atgtttagct atttatatag ccataactgt agtttttgtt aggaatagct gattgctctt
    15841 gttaattacc taaaatatgc tagactaaaa caaatgctag ttgaggaagg aaggaccctt
    15901 attgaataaa aaattaattg ccatcgatct ggacggaact accctcaatc aagattcgat
    15961 gattacatct aaaacaaaag agactctgaa aaaagcaatc aatgccggtc atcatgtcag
    16021 tattgctaca ggacgcccat tccgaatgag ccatcagttt taccaacaat tagaattaac
    16081 aacaccgatg gttaatttta acggcgcatt agtacacatc cctaatcagc actgggatgg
    16141 tgaaagagaa acgttgatca atcgtgaaat cgcttttgaa atcttatcgc aaaaaaagca
    16201 gctaaattta gattttatcg ctgctgaaaa tcgtgatact ttttttattg acagttttga
    16261 tttctttgat gaaaaaattt ttgcttcttc tcgtccagga gagaagaatt tgctttctcc
    16321 taaaaatttg acgacaaatc ctacatcttt gcttgtccga acagacaaac gttttgcagg
    16381 agctgtatct gctgaattaa cacgtcaatt tggcagttat gtcgatgttc ggacatgggg
    16441 tggacctact gccatcttag agattgtttc aaaaggaatc caaaaagcaa aaggcgtgca
    16501 agagattgct aactacctgt ctatcgatca aaaagacgtc attgcctttg gtgacgagca
    16561 taatgatttg gaattgttgg attatgcagg ttggggagta gctatggcta acggtactga
    16621 ccaactcaaa ggcattgcaa atgatgtcac tcctttgagc aatcaggaag acggtttagc
    16681 tgtttatctg gaaaaactac ttaaactata atagagaatt agattccaca aaaaagaggt
    16741 tgtgacaatt tttgtcacaa cct
//
LOCUS       DADVXB010000058        16411 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.059, whole genome shotgun sequence.
ACCESSION   DADVXB010000058 DADVXB010000000
VERSION     DADVXB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.059"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..565)
                     /locus_tag="KB902_001472"
     CDS             complement(<1..565)
                     /locus_tag="KB902_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808307.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSITSEEVTFSLDGTFMSEAGYYKHCYVEYRKGNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQ"
     gene            complement(589..2880)
                     /locus_tag="KB902_001473"
     CDS             complement(589..2880)
                     /locus_tag="KB902_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6808308.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIIEGRIIQCYVDENRAKQRLRIYYAKTSVIGNMIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHETRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVEDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVNNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQDGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNKPFLSFGAPNFR
                     YSNASYITDGDGSSLSINGSAGSSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKIA
                     RFEQSTVQVYKNFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            complement(2890..3627)
                     /locus_tag="KB902_001474"
     CDS             complement(2890..3627)
                     /locus_tag="KB902_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6808309.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDAEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFSLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            complement(3677..7108)
                     /locus_tag="KB902_001475"
     CDS             complement(3677..7108)
                     /locus_tag="KB902_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6808310.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            complement(7310..7672)
                     /locus_tag="KB902_001476"
     CDS             complement(7310..7672)
                     /locus_tag="KB902_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808311.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            complement(7691..8299)
                     /locus_tag="KB902_001477"
     CDS             complement(7691..8299)
                     /locus_tag="KB902_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6808312.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            complement(8311..8715)
                     /locus_tag="KB902_001478"
     CDS             complement(8311..8715)
                     /locus_tag="KB902_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808313.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            complement(8708..9109)
                     /locus_tag="KB902_001479"
     CDS             complement(8708..9109)
                     /locus_tag="KB902_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808314.1"
                     /translation="MVNDNSKEKERLNKQISAIKTSLEEHFKLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            complement(9099..9452)
                     /locus_tag="KB902_001480"
     CDS             complement(9099..9452)
                     /locus_tag="KB902_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6808315.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGE"
     gene            complement(9442..9753)
                     /locus_tag="KB902_001481"
     CDS             complement(9442..9753)
                     /locus_tag="KB902_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808316.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPDSLEYGLLIERCRYDWNRALGEFEQNFASELLGFIQHYALQEYIAGDGNG
                     E"
     gene            complement(9750..10625)
                     /locus_tag="KB902_001482"
     CDS             complement(9750..10625)
                     /locus_tag="KB902_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808317.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGARWIINLPKANYWKKVYLDSNRLYRYLRGQKTNVQIWTAEMWAQLWNMMYFNIGP
                     KVHEELNFCFATDPIEKFKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYAKAIKAVVR"
     gene            complement(10635..11795)
                     /locus_tag="KB902_001483"
     CDS             complement(10635..11795)
                     /locus_tag="KB902_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6808318.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVNNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKTAEPITALDAATMGGLMARLSKFNIEGVDDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(11795..12481)
                     /locus_tag="KB902_001484"
     CDS             complement(11795..12481)
                     /locus_tag="KB902_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6808319.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSAGTEAKKEQSVEEILNDVEEKRAEKIAAFTAAL
                     NKTFGQGDAK"
     gene            complement(12444..13622)
                     /locus_tag="KB902_001485"
     CDS             complement(12444..13622)
                     /locus_tag="KB902_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6808320.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(13642..15336)
                     /locus_tag="KB902_001486"
     CDS             complement(13642..15336)
                     /locus_tag="KB902_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6808321.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(15314..15628)
                     /locus_tag="KB902_001487"
     CDS             complement(15314..15628)
                     /locus_tag="KB902_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBB6808322.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(15731..16012)
                     /locus_tag="KB902_001488"
     CDS             complement(15731..16012)
                     /locus_tag="KB902_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808323.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(16017..16361)
                     /locus_tag="KB902_001489"
     CDS             complement(16017..16361)
                     /locus_tag="KB902_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6808324.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
BASE COUNT         4736 a         3468 c         2400 g         5807 t
ORIGIN      
        1 cttgtaagtt acctaactta gaaatttctt ctttcagagc atctaacttg tcttgtagtg
       61 ttttagcttg accagttaaa tcagtaatct gttgatttaa gctatccact ctacctttaa
      121 tttcagccat aaaagcatca aaagtttcgt tatactttcg aatcaactct tccaattgcg
      181 aaacgtattc atcagcttgg ccttgcgaaa tgtcagacac tcctagtgag aaaaaaatga
      241 tgtcttgcgt tgttaaaatt tgattacctt ttctatattc tacgtagcag tgtttataat
      301 atcctgcttc actcataaat gtgccatcaa gagaaaatgt gacttcttca ctagttatac
      361 tagttgcaac actatctaca taacggttag atggcgttgt tccttttaaa gtaaatgttc
      421 cgccactcgt atccatctgc aagccattta aaaatggttt aacagtcacc gtaattcctt
      481 tgtcaccttg acgagccata atagctttgg tgtagtttaa ttctttactg aaatctagag
      541 ccaaattata taaactgcta gccatttata tacctccttg tcttcgtttt aaaaacgttt
      601 ttggtcaagc actgtgctat catatgctgt atcctctttt aatctaacat cttcataccc
      661 tagtcgatgt gccactaaat tccatctaac caatacgttt ggcttactag tttcaatgat
      721 gaaatggtca acatcttcat gagtaacagc acacaaaact agttctgtag gtgtcacatg
      781 tgtcatatac cgacttagat ttactgtctc agcaaacatg ggatcaatat caacacgaac
      841 tttaccatca tcacctgtaa cggcttctcc ataatcagcg aaataatatt ctggagtttc
      901 ataagcgttc aatagtcgtt gtccataatg ttctgtcggt acggttgagt ttttagtacc
      961 tctaacagta aaatttttat atacttgtac cgttgattgt tcaaaccttg caattttccc
     1021 atcttcccat gaaccaaaaa aacaacctgg caacgttagc ataccatcac tagtaaattt
     1081 catagtcctg ccagctactt taaactccca tgaactaccc gcactaccat taatgcttaa
     1141 agaactaccg tcgccatcag ttatataact agcattgcta tacctgaaat tgggcgcacc
     1201 aaaagataga aacggtttgt tattgccatt atcccacgta ctaaaaacca aattcccctg
     1261 tggatttcta atcatgaaac caccaccagt tttcatggtg tatgatacaa taccggcatc
     1321 agcacttaca taatcacgtg cttctagctc cataatatct ttgttaactt tttttgagta
     1381 ccaagtcatt ttgccattgg caatacttgt tctataatca gtaccatcac taattaatgt
     1441 agtacctcta atagtaatcc ctactatctc accagctgta ataaacgagg cattaaatcc
     1501 gccatctaac gtccatgcgg tgtcatacgt tccattaata ccagttttag agaaaccaat
     1561 accagcattg ttgatttgta aaacattcct tgcggtattc ttatctggcg tgtccataat
     1621 caaaatacga ctaggtgctt ctttaggatc tagtaaaaca tacccaccat cttgaccagt
     1681 aatcatgtca gtttgatgat ctacaatatc attgattaaa tcactgattt cgccaccatt
     1741 tttcaattga tcaatggcat cattaatcaa attgttgaca ttattctctg tattttctaa
     1801 gaagtttgtt ttgacgtttc ctacaactaa tttatcgtat gaattggtta aaacattaaa
     1861 cgtatattcc acaattcttg ctgacatatt cacttttaac tgtggatgat acacatctac
     1921 tccgtcaccc atcgaaactt tttctagatc aacaaatttt tcatagcctc tttgatgcct
     1981 caatggtact aattcaatcg aaccactcac ttgtggtttc tgtttatcta tgtttgtttt
     2041 caaccagtct ttagcagctt cccttaatgt ggccacatca gtcgctttgt ctttaaaatc
     2101 aacaaaagaa acatatccag caggataatc ttccacgtaa tccgtgaaaa tgacttcttc
     2161 tggtagagtg atctcatcct ctccttctga cgaactgcta atgaatggat aaactccaac
     2221 taaaacactt tgagcatcta tctctaagtc gagaccagtt aagtttttag tataaatcgc
     2281 tttgatttta tgatccgtac ctagccttgt ttcatgacgt aatgtgttat tatctttaag
     2341 aaattcccca tgaaatcgat ctaggataga tccttccttt ccgccaaaga attctaaaaa
     2401 attcgccttt tctatcttca cattagcaag cgtatctact aacgatgaga aagaaaactg
     2461 cgaaggaata gctggttttg ctaaaacttt tgcgttttgc catgcctgag tagcagtgat
     2521 cttttctgtt ccgctgtcat atttattcaa caccgatttt cttatatcat tgaaaatagg
     2581 ttcagctttt acttctatca tatttcctat tacagaagtc tttgcataat aaatccgtaa
     2641 acgttgcttt gctcgatttt catccacata gcactgaata atacgtcctt ctataatcaa
     2701 gtctgcatta gttccgctta ttggataagt accctgaaat atctcggctc cgtttaattt
     2761 attgctaaca gtggctgtta accagtctga caaagcgcct aaaccttgtg tatcatataa
     2821 atgttcagct aaattattcg cgtcattttt atcgtaaata gttattaaat tatcgatcat
     2881 ctatttcacc taccttaacc cattacgata aatttgtatt ttgctcaaac cagtacaatt
     2941 aaaataatta atatccactt gcaatgtcgg atattgcatg gtcttcattt tgttggatcg
     3001 atctaaaata tctccgtccg attgctcttc gtagcaaagc attaaatcac tatcaatgac
     3061 tacatcagtt cctactacta agccttcaaa actaaacaca taatcattta agatgaactg
     3121 gcatgaagta gctgaaggag tgatgataat ctttggaaaa ctttcttcta aactattatt
     3181 cagcaaacta aatgactgtg gtttatctac ggttataggc acatcttctt gaactcttgc
     3241 gaatggtttc gcagtaatat ttacatcgaa ctctccccat tcaacaatat cgttttctgc
     3301 atccccaata tcgatagtct ggataacata atagacgttg ggatcatcag agaattctaa
     3361 tttctttgca tagtttaacc aatgacgcat gatataaaac gattgcttga acgcttgatg
     3421 gtcttccgca tcctctaaat agttatagtg caaagtaaac gacatatctt caaacgaata
     3481 atcttgtact aagccaccta accgtcctaa aacagaagtt tcaactctct gtctttttgg
     3541 agatggtatg gttggtcttt cagctaaagc caatttatgc aaataatcag gaaatccatc
     3601 gattatagaa tgtatacaat cagtcatttt ttcacatcct ttttaatact aaaaaacagg
     3661 agaaatactc tcctgtttaa cgccatgccg aagcattatc attttgaact tttgtaatgc
     3721 tgtcaatgat ttgttgagtt gtttgcttca tagtaacctc atctgcgtta ccatcaattg
     3781 tgaaattgaa ttcgtagtta ttcacaggtt gaatcgtttg tgccctagat gaaactgatg
     3841 tgctactcaa gatacgatca ccaatttctt gcaaaacaga tcttttcaaa ggtaaaactg
     3901 cttcaggtcc tgcttcaccg acaccgttca ttccacctag taaagttggt ttagtaaaga
     3961 tacctccttt agcatgccat tttacacgca aatgggggat ttgacctttt agcgggttaa
     4021 agctgccttc catgataaat tccggtaacg gaatatgtgg tatagaaata ttcaaattat
     4081 caaaaatgcc actgattttg tctctaatcc aatcaattgg agcgctaaca gtctttttga
     4141 tgccttccca tatgttagca attgtacttt taacattatt gaatatgtcg gaaacaatac
     4201 ctgttagatt ggaccaaccg cttgaaattg cattttttcc atcgtttact ttagagctaa
     4261 tagtgcttgt aattccattc caaagattca aagcagtatt tttgataccg ttccaaattc
     4321 cgctaatcca cgaagatata ctattccaaa cactttgaat ggcactttta gctgcgttta
     4381 tagcattgct tatactacta gtcacactat tccagatatt tgatgctgta gagctgattg
     4441 aattccaaat tccacctaac caactagata cagttgacca aatattttga attactgtag
     4501 cagctgcttg taccaagcta gtgattgtat tcttgatact gttccaaata ctagaagctg
     4561 ttgcactaat tgaattccaa atatttgaag ccgtagtact aatagctgtc catataccat
     4621 tccaccatgc cactactgga tcaaatatag tatggaatgt agttacaatc ccattccaag
     4681 cgatacttat ccattgtgtc atagtatccc aagtattttt aaggaaatca gaaataggtg
     4741 tccaaacagc ttgccaagct gcgcccaata actgtccagc tacatcaaaa atacccacga
     4801 taatattaat accagcttga atcaatgacg ttattaatgt ccatggtatt tgaacaattc
     4861 ctacaatgtc tgcccaaata atcgaccata cttctttgac tccgttccaa atatttgaaa
     4921 cccaatcaac gaatgtttgc caagtttctt ggactccttg ccagatgttg gaagctcctt
     4981 caactaatcc gctccatagc tctccaaacc aatcagaaac tccttgccaa atatcttgaa
     5041 cccaatctac aaatccagac caggtttctt taaccccatc ccaaactgat gaggctccgt
     5101 cttttatact ttcccaagta tcacccaacc aatcagtaaa ttttttccat aaaccactaa
     5161 accagtcagt aattgcaccc cagttcttaa ttgccacaat aacgcctgct ataacagcta
     5221 taattcctcc aattataagc atcatcggac caaataaata tgacacggct agtattgccg
     5281 gtaacagtat gccaaatgct gctgtaagac cacctatagc aacaatgaaa tcctgtactg
     5341 gttgtggaag attattaaac gcatcagcca tctttcctag aaaatcaatt actggttcga
     5401 gtgcatctat gattgtgttg cctataggag ctaatgaatc ctttaattca gctattttcc
     5461 cgttcaactc ttgcaacgga gtagtagaat cttcattcat tttttgtgca gatccactaa
     5521 catcatcaaa tgtatggtta acatcagtta aagattggac aactttcatc gcattatctt
     5581 cgccaagcgc agaccaaatt gtcgaagctt tatttaattg gtcgtattga ccatccatat
     5641 tgctaaaatc ttgaatcatg gaattaataa cgtctttttg tgttcctccg ccatttttcc
     5701 actcttcaaa agcttttcta gtactttcac taaacatatc catgttttgc tcaaatcgac
     5761 catctgttaa cgatattccc atttccttaa ctaagtcatt gactttatca aggttataag
     5821 cacccgcatc taaaccattt tgaagcattc cgaacgtttc atcagctgaa tatcccattt
     5881 gactccataa ttggctatat tctgccatat tgtcgcctaa ttcgtgcgtt ttatctaaac
     5941 cgttttgagt acccgaaacc attaaatcca ttgcatcttg agcactcaag ccgaaattga
     6001 ccattaagcc atttacacca cgtaacgttt catccatatc agcgcccatg gtgttttcta
     6061 ggaccatagc ttgttccgtg atattttgta aatcttgatt atttaaatct cctaaattac
     6121 gctttaccaa aatcaatgca tctgtggact gatctaacga ttctccaaaa cctttataat
     6181 aaatgtctct ggctacattc gttaattctt cagcctcttg tttagacaaa ccaaaattag
     6241 cttgtatctt actctgggaa ctacctacac tgttagcaga gtccactgct tgtttcccta
     6301 attctgtaag cttatcgcca atgtcgctta aaacgtcaga agcttccatt aaattattca
     6361 tatctatttt gcttccgata tcgtccaagt tagttgtatc tacattttta gcagcttgtc
     6421 ctaactcttc aaattcacgt tcagcatcat taagcttcgc ttccatctgc attgcttctg
     6481 tggatgtagc gccaaattca gactgtgtag cttctaactg tcgtcttagg atatctatcg
     6541 ttttctccgc attttcagat tgttgagaaa catattcttg ggctttcgct aatttctcgg
     6601 cttcagaagc tgattgacca gcagttgctt gccatttttt gtattcggat tcaatcagag
     6661 aagcactagc ttgaacattt ttttgttcgc tatccaactg ttgcattgta gactcgtacg
     6721 tctgtatttc gccttttgct tgagctagtg cattactcgt tttatcaatt tcgtttgaca
     6781 aacgttgttg cgctgtttgt tgattaatca gttctctttc aagtttctga acttcggtgg
     6841 aattttctcc ataatatttt ttcgcattgg ctaaacgttg gctagttact tcaacttttt
     6901 gactttgtaa ttcatactgc ttttctaaag aagataattt acttcctaac ttgtctgatt
     6961 cagaaccagt ctgttgtaat tgagcttgtt ctagttttaa ttctgctcta tttttagtta
     7021 attcagcact gatttctttt aacgtagatt tcaatccgtc atcgttagct atgaaagtta
     7081 cttctgcttc tgttctcttt ttagccattt tttacctcct ttctttagtt tttctgggat
     7141 tggtttattg catagttttt ccatccttca taagcactct tgttgtaagc catttgcaaa
     7201 atgtcatcta aacagatatc gcttaaaacc aaatctgaag gcatagaaaa aacgtcggtc
     7261 aacatcgaat agacatcgac ccacgtttca actaagagct ttggaatttt tacttttgaa
     7321 gctttttttc cttatttgct ttttcaaatt ctttttgata agcatcgcgt gcttgtttga
     7381 acatcatcaa ttgataaata tagctggcag tagccatatc aaaatcccat ttatcgataa
     7441 attcatcgaa tgaaatataa tcagtcatgt tcgcttggcg gtaagcaata tacacagcct
     7501 ttgcaccttg aataacagaa atatccatgg atccttttcc cacagtcatt tttgcaaact
     7561 cgtctgtgtt aaaatctcta ttgatcatca ataatttctt gatattcagt ttaggttcta
     7621 aattcaaaat tgttccatcg tttagttcaa tttttgagta atcttcgttc atttcgctac
     7681 ctccgttttt ttactgtgat tgagtggccg tagttgtcac aactgaagtt tttttaatca
     7741 catcagcaga tagattcgtc atccattgat ctgttaagtc ttcttcaagt tctgcaacaa
     7801 ttgcttcatg ataaaattta ccaaattcat cttgcataac ttttgtttct agttctaacg
     7861 cagctacttc atccgcacca ttttcaatag agaatgttaa tcctgtattc gaagtgcatg
     7921 ctaacatacc aactaacttt ctattttctt cgaagtcatc cacgatctct gcagcaagtg
     7981 agaaatcttc gcctacggaa tcaggaccgt aagagtaaat gcctggttta atacgtccat
     8041 cttgtttcaa cccattgaaa cgtcgataaa cttccatcgg tacatgtgca gtaattgtta
     8101 ccgtcatatt gattggttta gattttgatt ttacttctgt cgctccacat tttttaacca
     8161 ccgtttgcat ttctgtttcg ccatctaatt gtccattaca attcgttgcg attgcatttc
     8221 ctgcgttctt aaaattaaaa gcaattcgtt tgatacttac gttatcgaac gttgttacta
     8281 cagtttttgt tttagccatt gttgttcccc ctatttattt aatttatcga attgacgaat
     8341 cagaagttct gtaattggat caagtgcaag acctaatcct cttctcataa attcgtccgg
     8401 ctgatttctt ttagaagtac ctatccccaa atcaggatat tttaaatact caaattttct
     8461 tgtaggtcta atgatgaaac ccaaattaat gtattgagtc ttaagtggac gactattttt
     8521 tgcgtgttgg tgccctcttc ttaaatctgc ttcagaaaca ggaatttttt ctgtaatcct
     8581 atccactgca atagccgaac cttttgattt caatgcttcg ttaatcagtc gttcgctctc
     8641 gcttgaatag cgttccatcc gcacaagaag ttcatcatgt ccatttattt ttagctccca
     8701 actattttta gccatgacaa tcactcttca ataatcgtct aaacgtaaat accaattgat
     8761 cgatatagcg atcttgattt tctagtttta aatggttggg atccattctc tgaaaacgaa
     8821 tcgaacgatt ttgaatcaat gaaataatat ctagtgaatc tcctgttaaa tcttctctat
     8881 tttctgaata gaaagttaga tatagatttt gacccacact atattttggt tcagtgatca
     8941 tttctatttc tcctgtttcg agaatgaagt aattaaaatc atcaggtagc tcatcctcgc
     9001 caacagagtc ttgaaagagt ttgagcttaa aatgttcttc taaggaagtt ttgatagcag
     9061 aaatttgctt atttaaacgt tctttttctt tagaattatc attcaccata ttcacccaca
     9121 ctttcaagat aaaaatagat ataaaaatta tcgtaatcgg catagataac gttgtaacgc
     9181 atactatcga ttacgataaa atattgatct ttattaaatt tcttggcgat tggatgaaat
     9241 ggagtcttta ctttcttagt taatttcgat cccatcgcat ccatagctgt tatatcacta
     9301 tctctcatgg aaagatttct aaattttaaa gaagtgattt ctgtatcttc tacaccaatc
     9361 ttttttccta gttcatttct tttggtggtt tgcgttaaaa tctttaacca accatcgttg
     9421 aacgtttctt cgagtctacg attattcgcc attcccatca cctgcaatat attcttgtag
     9481 cgcataatgt tgaatgaaac ctaataactc gctagcgaaa ttttgttcaa actcacctaa
     9541 agcacgattc cagtcgtatc tacatctttc gattagcaat ccgtattcta agctatcagg
     9601 agaaaaagaa agagttgtac tcactttact ttgtaaataa acagcatttt tagctatcat
     9661 ctttttaatt gattcatctt cttcgttcca ggtaacgtaa atattatcct tcacagctat
     9721 tagcaattct tcagtcactt gttcaggcgt catctaacca ccgccttaat tgctttagca
     9781 tatgcgtaag agcatttttt cttgtttaca aatgataaat cttcatcaaa aggcgtggaa
     9841 gtcacgtatc tccctttgaa aaataaatct tcatcatttg ttgttactcc agcgttatgc
     9901 aagattttta cttctttaaa tttttctatt ggatcagtag caaaacaaaa gtttaattcc
     9961 tcgtgaactt taggaccaat attgaaatac atcatgttcc aaagctgtgc ccacatctcg
    10021 gctgtccaaa tctgtacatt tgttttttgc cctctaaggt agcgatatag ccgattagaa
    10081 tctagataaa cctttttcca ataattcgct ttaggaaggt taataatcca ccgtgcgcct
    10141 cctgaattag tgtttatagt ttccaaagat tctactgtaa catttacaat atttgccata
    10201 tcttttagaa tattttctcc gttttcacag cttctaatat aatcaagact tagataacta
    10261 cagcagtcgc tacaatacca aacatcatct ttagaaggca atttgcgcaa attaattctt
    10321 ttattgaaaa tgacatccga atcgatatag aaatatcggt cgtcctcacg cgaatgatct
    10381 tcttctaaat atttccacca taaatatggt ttaatcgaag gaatatactc tttgtcgtcc
    10441 cgcagatcat cgtacacatg aacttcaacg ccatattcct tctcaaaaaa aataggaatc
    10501 tgatcatcgt gtctgctgaa aagcaatacg atatctttga ttcctagttt cttcagatta
    10561 gttaaacaaa cttcaagctc ccatttaaac cgattgattg ccggctgaca aagaatatac
    10621 ttcattctga tcacctacgc ttgtgttgta gttgttgtgg ttgttggttt tgtagttgta
    10681 gtagtagttc ccaaagcgct aatatctaat acaatgaaac tatcgttacg tttaggttga
    10741 ccgtttgcat attgtttagc tagataaatg cgttcgtctt caacaaaatg gtattcatct
    10801 gaagcttcaa tttttagtgt agatcctaca cccataaagt aatctgaagc taccccaata
    10861 actgcttttc cttctggcac agcagttgac tgcaagtctg aaactggtac tggtaatact
    10921 tgtacgtatt caccgttagc agttagtaca gtcttagctg ggaatacttt agaccagtaa
    10981 tcagttggat tcacaattag gaccacatca gaaggattca cattacgata aatcggatca
    11041 tctacacctt cgatattgaa ttttgatagt cgtgccatca aaccgcccat agttgcagca
    11101 tctaaagctg taataggttc tgctgttttt tcagcatatt ctccgctagt ttgtttgctc
    11161 atgtcgcgca tcattccgac tggcatatct ttaccagtac catcaacaat tgcttgttct
    11221 aatgcaattc tcaatgattc aactaaaaca gtacgaacat aacgatctaa ccatactgga
    11281 cctaagtcaa gcattgcctt acatacagga atataacctg atagcttgaa ctgcttcatg
    11341 ttaattacgt caaagccatt atctaaaact tttttaacag cttcgcaaag tttgccccac
    11401 catgctggat tgactccacg tgacacgatc cattctgtta caccagttgt gttaacaaaa
    11461 gtaatttttt gcaatagtgg atgagattgt tctagatctt caaatacgcg ttcaaataca
    11521 gtagctggta ctaattcttc aactcctgca aaaccttcat tattcactac ttcgttatag
    11581 aattttgttt cttgtgtagt tagtacacgc tgcccacggt tcattaatac taattgatct
    11641 tgattttttg ctgttgcttc ttctaaaatt ttatcctgta tttccttaga taaacttacc
    11701 atagctgcgc taaaagactc ttcgttacca tctttaaaag ctttcatcaa ttggtcgctt
    11761 gcagctgtta caccttttaa atttttaact gtcattattt tgcatctcct tgtccaaatg
    11821 ttttatttaa tgctgctgta aatgcagcaa ttttttctgc tcttttttct tcaacgtcat
    11881 tcaaaatttc ttcgacgctt tgttctttct tagcttcggt acctgcgcta ttttctgcat
    11941 cgataatttc atcgaccaat ccataactca aagctgtttc tgcatccata aacgattctt
    12001 tttcaagaag ttcttgcaat gcttcatctg tgccattgaa tcgtgtttta tatgaagcct
    12061 ttaccgattt atcaattgat tccagttggt cagcaatcgt acggaagtca tcgacatttc
    12121 cttctccgta tgtggaagcg cggtgaatca tcaattgtgc attgttgtag atttttatag
    12181 tatcgccagc cattgcgata attgaagcag cactagcggc taagccgtta atcacaacgt
    12241 taacttttgc tttatttgac ttaagtaagt tcccaatagc aatcccttga aatacgtctc
    12301 caccgtttga attaattact acttcaattt cttcttgatc acctagacta tccaaaatat
    12361 ttttgattcc cttgtcagta ttcccttcaa agaaccaact agaaccaata aatccctgaa
    12421 taaaaatttg cggtactgcg ccttcattct ttactgctag aaatgttttc attgtcgtca
    12481 ttcgcctcac ctcctttcga tacttgttga ttgtttttag ttataaatat ttcatctgcc
    12541 atcgccttat cagagcgatc atttccaacg cgttctcttc cttcgttgat tgtaaatact
    12601 ccatttctaa tgcctacatc aatagcgtca accaaatctt tgaagctagt aatcttgatc
    12661 atagttgtat ccacacgtac aaaattccct gacaagtatt cttctacttc atagagacta
    12721 gcgttaaacg catcctgaat aagttcagca atcggtatga tttcgaacat taaaaaagcg
    12781 tccacttgat ccgataaccc actcatgtct ccctttagta ggtttttcgg aacgtgaaac
    12841 gctgctgctg tcatctcaaa gatgtcgtct attaagtttt ttatatctct tgaattgctt
    12901 tggaagtttc cgctgaaatc ttctaatgtg tactcatttt gtaattgaaa taccgcacct
    12961 gcattatcag cttccataaa agccttaaat tgtgatgtca tcattttatt gatttgatct
    13021 tgtgttgtat tgtcttgcgg tcggaataaa ttccctttca gtacgtatct acgagcgtta
    13081 gagcgcttgt aaacattcat ggcactagaa atgagtttcc catacgcttg ataatacgca
    13141 tcgactagtt gcctaatttg ttgatctgcg tattttatat agataacatc actttctaga
    13201 aattctctat caaggactat gttgttaatt tgcacttgag aaaacacatc atctttcaat
    13261 gcatattctg tgacatccca actatccgca ataaatattt cgctagaatt attagacgga
    13321 gaaacgatca atacttcatt gtagaatatt aatctcctga tcagtttttt tctaaattct
    13381 gttgcattat ttttcttatt aggagctaca ttcagcctat agtaaagatc attcttttta
    13441 ttttttccat cttcatatga cttgaattcc gctttactca tcgcatttgc aatcaaatca
    13501 atacaagttt caatcgcaaa ttttcgatac acaaaatcaa cttgcaattt acaaaagtat
    13561 tcttctaaag gaaccgttgc tttttttgtg aagtatccta ccgccttttg aaaaatcccc
    13621 actttctcac ctcctttcaa gttagaatac tagaggagta aatccagttc ctgtattttc
    13681 tactgagcta tttgtgactg ttacaggagc agaatcataa atatcatcta aaaaattcaa
    13741 accatgaagg aatgaaaaaa agccatccgt ttttctagtt tcaggttcta ttttttcata
    13801 gcgtatattt ccattagaaa tatgctcttc atatacattc atgcaatacc aacgcataat
    13861 cgcatcgtca ccaaaaaata aacgttgatt aataaaaagg tcatcaacca gatcttttaa
    13921 cataccatgt gtaacagatc cgcttcgaac aatttccaca gtaaaacctg cttcttctaa
    13981 agcgggcttc aatatttttg cacggtacat atccatagcg atttttttaa tataatattt
    14041 attactcatt tcaagaaacc aacctacaat ataatcagct tctatatttt ttccatgaac
    14101 gatctgtgat tttccttgat ctatagaaat atctataacc tctcgtttga tgttttgtaa
    14161 tcgaagggct gattcgtgga taaaagtatg ttgtgtaaaa taaacatctt tatcgtattt
    14221 tcctagcaac ccaacgctgg caaaatctcg tctatcagca aaatcgactg ttcctatcac
    14281 ttcatccatt ttttcaggaa attctttttc tttcgtatgc agaacatcat catatgaagc
    14341 aacagcaaat cgtgtatctt ccataggtct gttcattcgt ttggtcatga acgtaagtct
    14401 taaaccagca ttacgttgca tttgagagta ttcttgaaac attttccgtt ttaaatctgc
    14461 attgtaatta atagttggac aagctttttc ccacatgtcg ggatcatcaa cttcattatc
    14521 gttatccaag cgacaaataa atggaaacaa actagaaaat tctgctccat ccttgtcaat
    14581 tccaagttct ccagaaagaa tcatttttga ttcttctata atgtcatcaa gcggaccacc
    14641 acgaacatga ccattagttg tatcataaaa ttctctataa tctcgaattt taccaccacc
    14701 agaagtagcc acatttatca ttgaataatc ttcattttcg tgaatttcat caaagcggtt
    14761 tgcacctggt cgcttcccat cttttgttct agcatttgcc gtgttataac gaagtttgct
    14821 gtttgtagcg atattttgaa taacttcctt cgtagcttta aatacttttt tatctaaatc
    14881 aggatgatct ttaattactt taaatacatc atcaaaacta gtctttgctt ggctttcatt
    14941 attggcatag atatcaatat cataattttt aataccgtgt ttagcggtta gtagaaagaa
    15001 gttgttccaa gaagcaaaac cagttttacc attaccacgt cccattaatg aaagatatct
    15061 attgaacact agtgttttat cttttttcca tcgaacacca taaataaaac attgtagaaa
    15121 tttttcccac ggaattaatt cgaatggaaa gtattgtgct ggtatattga ttgaatcctc
    15181 taccatctgc ttatcgaagt aaatatcttc tctagtaaag actctttctt ctagataatt
    15241 ttttagcaat aattgctctt tgcatacctt gatagtgcct tcttctatag ctttgaacca
    15301 attttcaata tgcttataac tcaggaattg attcatttgc ttcacctacc aattcaggag
    15361 taatggcaag tttatccaac atcaatccca tttgtttgtt gacagaaaca agcaacgcta
    15421 ctgattcatt ctttttacca ttctccagtc taatgccgtt ctcggatata tcttcttcca
    15481 gtgatatcgc cgtttcccat aaactgatat aacgatcaac attatctaag aatggctcaa
    15541 tatttgtttt ctgactttcc aattggctta ttaaagagcg gcgtaatttt tctctgtagc
    15601 gattttgaga caattcgttt ttaaacattt tagccctcct ttcatgataa agttcgaaaa
    15661 aatctctttt cctgacagcc ccctccgttt catcaccccc aaaaaatttg cgatttattt
    15721 taaggggggg ttatctcacc atcggaatga aagcttcagc gaagtcaatg taataattaa
    15781 tctcttcaat actatatcca aaaacatttt ttattctttc gacgttatta tctttattca
    15841 acgcttctct tacttgattc actttgtatt tactacaaca gttatctgat aacagatccc
    15901 taatacctac atagcgaacg tatatcaaac gtttaattaa tccctgagta taagatgaat
    15961 actcttcaat cttttctgta tcatactctc tgccattatc attgatgatc atgcacttac
    16021 cacctttcac ttgcatcgaa gttagcaaag ctttctatct tcttctcttg tttatctaat
    16081 gctgtaagat atctgccatg aacttcatta tgatgttcaa cacataaaca aataagatta
    16141 tctaaatcta aagctaagtc aggtctatcc ttgacttcct ttatatgatg aacgttctct
    16201 actctatgat acttacctag tcttctacac tcttggcatt catagtgatc tcgtttcatc
    16261 gctttctctc taagcctgcg ccatttagga gactgataga acttaaccaa acgatcttct
    16321 cttgtcaact gtaatagcca tctatagaat tcctcggtca tgttccgtct cctttcgcaa
    16381 tcttatttaa tgcttagcta ttcttttgcc a
//
LOCUS       DADVXB010000059        16269 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.060, whole genome shotgun sequence.
ACCESSION   DADVXB010000059 DADVXB010000000
VERSION     DADVXB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.060"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            105..572
                     /locus_tag="KB902_001490"
     CDS             105..572
                     /locus_tag="KB902_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBB6808325.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            579..3071
                     /locus_tag="KB902_001491"
     CDS             579..3071
                     /locus_tag="KB902_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBB6808326.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            3292..4215
                     /locus_tag="KB902_001492"
     CDS             3292..4215
                     /locus_tag="KB902_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6808327.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            4221..5474
                     /locus_tag="KB902_001493"
     CDS             4221..5474
                     /locus_tag="KB902_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6808328.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDIEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            5608..6954
                     /gene="gor"
                     /locus_tag="KB902_001494"
     CDS             5608..6954
                     /gene="gor"
                     /locus_tag="KB902_001494"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBB6808329.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(7648..8601)
                     /gene="menA"
                     /locus_tag="KB902_001495"
     CDS             complement(7648..8601)
                     /gene="menA"
                     /locus_tag="KB902_001495"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBB6808330.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(8614..9717)
                     /locus_tag="KB902_001496"
     CDS             complement(8614..9717)
                     /locus_tag="KB902_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBB6808331.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(9807..10763)
                     /locus_tag="KB902_001497"
     CDS             complement(9807..10763)
                     /locus_tag="KB902_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBB6808332.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAD
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            11044..12978
                     /locus_tag="KB902_001498"
     CDS             11044..12978
                     /locus_tag="KB902_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6808333.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKEQKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVLKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            13435..13851
                     /locus_tag="KB902_001499"
     CDS             13435..13851
                     /locus_tag="KB902_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6808334.1"
                     /translation="MSLKEFAEKSLLKPWDVFIIFLLTVLSFLPVMIFGLQQNTVTAE
                     KEAVLRVDGTEIKTFPLMAGEESYTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            13865..14431
                     /locus_tag="KB902_001500"
     CDS             13865..14431
                     /locus_tag="KB902_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBB6808335.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            14454..15440
                     /locus_tag="KB902_001501"
     CDS             14454..15440
                     /locus_tag="KB902_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6808336.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSIGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(15595..>16269)
                     /gene="scm"
                     /locus_tag="KB902_001502"
     CDS             complement(15595..>16269)
                     /gene="scm"
                     /locus_tag="KB902_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6808337.1"
                     /translation="SSDSTTTTSDSTDTSASSDSSDSTTTTSDSTDTSASSDSTDTTS
                     TTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDSSTTTSDSTDTSASSDSTGTKTT
                     SDSSDSSTTTSDSTDTSASSDSTDTISTTSDSSDSSTSSDSTDTSSTTSDTRHASVSF
                     SKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMS
                     YKKSKR"
BASE COUNT         5152 a         2894 c         3436 g         4787 t
ORIGIN      
        1 tttgttgatt ctaaaggatt tatttaacaa aaagcgttct tctttctttc tattaccaaa
       61 ttcgttataa ttaaggtcaa tattagtcaa agggaatgaa taagatggca catcagaata
      121 cctcggattt aattgaatca tatataaaga aaattctgga aaatagtgaa atgatcgaga
      181 ttcgaaggat tgaaatggca gacctcttta actgtgttcc ttcacaaatc aactatgtga
      241 ttaatacccg ttttaccatc caacgtggtt atctagtaga aagcaaacgt ggtggtggtg
      301 gttatatacg aattgcaaaa gtaaggattt cagataaaaa acaattactt gagcagataa
      361 atcagttatt tgatgataca atcagtgaga aaaatgcttt tgctattatt caaaaacttt
      421 atgaagacca aataattaca aaaaaagaag gaaacttaat gttgagtgca attgcaaaaa
      481 acacattgaa tttcaatgaa tatgaagatc atacacgtgc tcggattctc cgagcatttc
      541 tggaacgttt aagttatgaa gatgggaagt gagattagat ggaagaactt tttactgaaa
      601 gagcccaagc agtattagaa attgcacaag aagaagcaaa acgattgaaa catcaatcag
      661 ttagttcaga acatgtttta ctagccttag tggtcgagca aaatggaatt gctggaaaag
      721 tattacgtga aatggatttg aatgaaacgg aaatttatga agaaattgaa catctgattg
      781 gttatggtgg tatccgttct taccctaaag gagtctttct tccatattca ccaagaatga
      841 aacaagtttt tgctttagct agcagcgaag tgaagaaaac tggttctcaa aaagttggaa
      901 cagaacatat tttgatgagc ttattaaaag atgaaagtat catggctact cgaatcatga
      961 tcaacttagg tatcagcctt tcaaaagccc gtcaagttct gaaacaaaaa atggggctag
     1021 ctggtgattc tgctggaaaa ggaatgaatc gtcgtagaaa tgtaaatgta caagataaac
     1081 ggcaaacacc gcaaggaaca cctacgctag attcattagc acgtgatttg acgaaattag
     1141 caaaagaaaa caagctggac ccagttgttg gtcgttcgag agaagtgaaa cggcttatcc
     1201 agattcttag ccgacggaca aagaataacc ctgtactggt gggtgaacct ggtgtaggca
     1261 aaacagctat tgctgaaggg ttagctcaaa aaatcatttt aggtgaagtg ccagaagaca
     1321 tgcaagaaaa gcgcctgatg atgcttgata tgggatcttt ggttgctggt acgaaatatc
     1381 gcggtgaatt tgaagatcga atgaaaaagg tcatcgacga aatctataat gatggtcaag
     1441 taatcttatt cattgatgaa ttgcatacct taattggtgc aggtggagca gaaggagcaa
     1501 ttgatgcttc gaatatcttg aaaccggcgt tagctcgagg agaattacaa acgatcggag
     1561 caacgaccct agatgaatat caaaaatata tcgaaaaaga ttctgcatta gagcgacgtt
     1621 ttgctcgcat tcaagtagat gagccaactc ctgaagaagc agaagtgatt cttcaaggat
     1681 tgcgtacaag atatgaagag caccatggag tggagatcac agatgaagct gtacgagcag
     1741 cagtcaatct ttctgttcgt tatatcactt ctcgtcaact acccgataaa gcaattgatt
     1801 taatcgatga atcagcagcg aaagtccgtt tggatcaaac cgatcactta acaaaatcaa
     1861 ctgtgatcaa actagaaatc gatgaactag tacaagaaaa ggaagcagca atccaaaaac
     1921 aagactttga aaatgctgct caattacgca gacaagaaaa agcactacgt aaaaagctgc
     1981 aaaaagtttc tgcaattgaa gcaaaacagg agcaaggtta ttctgatcgt gtaacagaag
     2041 aagatgttgc tacagttgta tcggagtgga ctggtgtccc tctacagcag ttggagaaaa
     2101 aagaaagcga acgcttgtta gaactggaag gacttctgca tgaacgtgtc gttggtcaag
     2161 atgaggctgt caaagcagtt tcacgtgcga tccgccgtgc acgaagcgga ttgaaagatc
     2221 ctgatcgtcc aattggttca ttcatgttcc ttggaccaac tggtgtcgga aaaacagaat
     2281 tggccaaagc actttcagaa gtcatgtttg gaagtgaaga tgccctgatc cgtgttgata
     2341 tgtcagaatt tatggaaaaa tacagtacaa gccgattaat cgggtctcct ccaggatacg
     2401 tagggtatga tgaaggtgga cagttgacag aaaaaattcg tcaaaaacca tattcagtga
     2461 ttctcttaga tgaagtggag aaagcacatc cagacgtttt caatttactt ctgcaagtat
     2521 tggatgatgg tcatttaaca gattctaaag gtagaaaagt ggactttaga aatacaatca
     2581 tgattatgac ttcaaatatc ggagcgacac aaattcgaga agaaaaaaat gtcggattca
     2641 atgtccaaga tgttactaaa gatcacaaag ccatgcaaaa acgtatctta gaagagttaa
     2701 agaaagcttt ccgacctgaa ttcttgaatc gaattgatga gactgtcgtc ttccattcat
     2761 tgagtaaaga tgaaatccat acaatcgtcc aaatcatgag caaagcgatt atcaaacgat
     2821 tgaaagaaca agatattcaa gtgaaaatca caccatctgc aatcgatgtg atcgggaaag
     2881 ccggatttga tcctgaatat ggtgcacgtc caatccgtcg cgcacttcaa aaagaaattg
     2941 aagatcgatt gagcgaggct ttgcttggcg gagaaattcg tttaggtgac cacgtaacag
     3001 taggtgcttc aaaaggtaag atcacattga atgttcgcgg acctaaaaag gaaacagtag
     3061 gttccctata gttatttggc ctgtgtagct gaatttttat aatagtaaga cttgattaag
     3121 aggttgtgac aagatttttg tcacaatctc tttttatatt tggacagaat atatcgaact
     3181 ttattttgat tttttgtgaa ataattttca aaaatccgac tttaaataga agaagtattg
     3241 gaaagttttt agagctatgc tactattatg aagttgtagg aggagaaaat tatgatcgaa
     3301 ctcataacca cagtagaaac tattgaacaa gcagaacagt tgcttgctgc aggtgcagat
     3361 acactatatt tcggtgaaga gcaatttgga ttgcgtctgc ctgcttcatt tacacgagaa
     3421 gaacagcgac aattggtaga attagcacac aagtatggta aaaaagcgaa tattgctgta
     3481 aatgggatca ttcatcctga aaaaatgaaa aatgtacctg aatatttggc ttttttaaaa
     3541 gaaataaacg tagatgtgat cacagttggt gatacaggta ttatttatac gatgaaaaaa
     3601 aatcctgaat tgcgtatacc gtatatttat gatgctgaaa cattagtaac gagcgcacgt
     3661 caaatcaatt tctgggcgaa aaaaggcgca gttggagcag tacttgctcg tgaagttcct
     3721 tttgaagaga tgaaggcgat ggaagaaaaa ctcgatattc ctgtagaaac ccttgtgtat
     3781 ggtgctacat gcatccatca atccaaacgt ccactgctac agaattacta taactatacg
     3841 aaacaagacg aacaaaaaga tcgtgaaaga ggtcttttta tctcggaacc taaaaaagaa
     3901 gagacacatt attctattta tgaagatagt catggcacac atatttttgc cagcaatgat
     3961 ctgaatctct cgaatgaatt gaatgaactt tatcagcatc attactgtac atggaaattg
     4021 gacggattat ttactccagg cgaaaaattc gtaaacatca ctcgactatt cgccgaagca
     4081 aaaaaacaaa ttttagaagg tagctgggat caagaaaaag cggaaaaaat gactagcgaa
     4141 atcagtaaat tgcatcctga aaaccgtgaa ttagatacag gattctttta tattgatcct
     4201 tctgctatca aataaggagt atgatgaaag aaatgacagt aaaaagaaaa ttgaaacgac
     4261 cagaaatcct agcgccagca ggaacactgg aaaagttaaa aaccgcgatc cattatggag
     4321 cagatgcagt atatattggc gggaatgcat atggtttaag aagccgtgca ggtaatttta
     4381 cttatgaaga aatggctgaa ggagttgctt ttgcaaaaga acatgatgcg aaggtatacg
     4441 ttgctgctaa tatggtcacc catgaaggaa atgaagatgg agcaggggaa tttttccgca
     4501 gtttgcgtga tgtcggtatt tctgcagtaa ttgtttctga tccagctttg atcgaaattt
     4561 gtgcgacaga agccccaggt ctgccgatcc atttatccac tcaagcttca gcaactaatt
     4621 ttgagacatt ggaattctgg aaagaagaag ggttggaacg tgtcgtttta gctcgtgaag
     4681 tttcaatgga ggaagtggca gagattcgta aaaatacgga tatcgaaatc gaagcattta
     4741 tccatggtgc catgtgtatc tcttattctg gtcgatgcac attgtccaac catatgtcga
     4801 tgcgggatgc aaaccgtggc ggatgttctc aatcttgtcg ctggaagtat ggattgttcg
     4861 atatgccttt tggtcaagaa cgaaacagtt taactgatac aggcgaagtg gaagaagaat
     4921 tctcgatgag tgcagtggat atgtcaatga tcgaacatat tccagaattg attgaaaacg
     4981 gcgtagacag cttcaagatc gaaggaagaa tgaaatcgat ccattatgta tctacggtgt
     5041 caaatgtcta taaagcggct gtagacagtt atatggaaga tcctgaaaac tatgtctgca
     5101 agcaagaatg gatcgacgag ttatggaaag tagcacaacg agaattagct acaggttttt
     5161 actacaatac accaactgaa aacgaacaat tattcggtga acgtcgtaaa atcccagtat
     5221 ataaatttgt cggtgaagta ttatcttatg atgaggcaac acagattgct acgatacgtc
     5281 agagaaactt gttttctgta ggagatgaaa tcgaatttta tggtccagga ttcagtcatt
     5341 tcagtcaaac cgttgaagtt atgcataatg aagaaggcga atccattgac cgagcaccaa
     5401 atccaatgat gattttaact atgccagtcg cacagccggt gaaacctgga gatatgatcc
     5461 gaaaacgtaa ataaggaaaa agctgatata tccctgtttt aagcatcttc gcatacaaaa
     5521 ttcaagaaaa gtgttacact tgctttctgt agaaaaagga tcgttaaata aaggttttga
     5581 ttgatctctt caataaggag gaacaaaatg caaatatatg attacatcgt aattggtggc
     5641 ggctctggcg gtattgcttc agcaaacaga gcagggatgc atggcgcaaa agttttgctg
     5701 attgaagcga atgaattggg cggaacatgt gtcaacgtcg gttgtgtacc taaaaaagtt
     5761 atgtggcaag caagtacgat tttggaaaca attgaacgag atgcctcaag ttacggtatc
     5821 caagcagatt taaaaaatgt tgatttcgcc ggtctagtag aaagacgaga aaaatatatt
     5881 gattttctac acggtgctta tcaaagagga ttagatagca atcatgtcga ggctataaaa
     5941 ggttacgcta cttttatcga tagtcaaacg atcgaagtaa acggtgaaac ctatcgtgct
     6001 cctaaaatct tgatcgctac tggaggccgt gcaagtaaaa tgaccattcc tggtggagaa
     6061 tacgccattg attcaaatgg attttttgaa ttaacagagt tacctaagag agcaatcgtt
     6121 ttaggtgctg gatacattgc ggctgaactt tcaggtgtat ttcgtggttt aggtagtgaa
     6181 gtcatgtggg catatcgaaa agaacgacca cttagaacgt ttgataaaat gctttcggac
     6241 aatttgatcc aaatgtacca agaagctgga ataaaaactt acgcacatca tattgctaaa
     6301 gaaattacta aaaacaatga cgaatatacg gtgctatttg aaaatggtga aaccttaact
     6361 ggtgattgtg tactttttgc cggtggacgt gtaccaaata ccgaaaaatt aggtctggaa
     6421 aatacaaatg tggaattgga caaaaaaggg tttatcaaag tagataaata ccaaaataca
     6481 acggatgaac atatttttgc tgttggtgat gtgatcggta aattagatct gactcctgtt
     6541 gcaatcgcag ctggtagacg tttatcagaa cgtttattta atggaaagaa agattcttat
     6601 cttgactata aacttgttcc gacagtcgtc tttacgcatc caccaattgc aacaattggt
     6661 ttgacagaag aagaagcatt ggaaaaatat ggcgaaaatg aattgaaagt ttatcgttca
     6721 cgctttaccc caatgtactt tgcattaaat gattatcgcc aaaaatgcga aatgaaattg
     6781 atctgtgtcg gaaaagaaga aagaatcgtc ggcttacatg ctattggtgt tggtgtcgat
     6841 gagatgctgc aaggttttgc tgtggctatc aagatgggtg caactaaaga agactttgac
     6901 aatacagtag ccatccatcc aacaggagcg gaagaattcg taacgatgcg ataatttaat
     6961 attaacagtt ccaacagctt tttattgaac aaaccatgta aaaccagaaa atcagtatac
     7021 tgattttctg gttttttgtt ttttagttat ttatgtaaga ttgcttcgat aattctcaaa
     7081 acgaaataag tagggaagtt ggagattttg attatcttcg taactgacga agagtaaatg
     7141 aatccatttg gtatgcactc ttaagttcaa aatattggta tcgatgttta aaagaaatag
     7201 aaatgtatcg aagaacagat gattaaaaaa gtgtgacttt gtataaataa attagaagaa
     7261 gcaaacgagg atgttaaaag aataccatat agttaccaaa ccaagaaagt tctcgtcaag
     7321 ttcgctggta cgaatcacat caagtgacaa aagggactgt gaaaaaagtt gtgtcatagt
     7381 tagtcacttt ttccgaacaa atggtgttct cctgccaact cccaatcaca agtcacaata
     7441 ttcataaaac atgagaagct gttttttgaa cttgttcctt gcgactcgga gctaaacggc
     7501 agactcacga cctctttctt aaatggtgtt caaaagcttg catctgcggt aataagccca
     7561 accaaacgaa aaatataagg agctattttt atttggctgt tcttattact tgatgcaggg
     7621 cagctttttc acaacctctt catgctgtta aatggcttgc ataatgattg ttagtaatag
     7681 ccccaataca taactggcat tgaataagac catatttttg atggaatagc tgaaactgat
     7741 aggctggggt aacgtttgct tgaattgatc caaatgcttc ttcacaattg gcaaggtcaa
     7801 gaaggtgacc aagatcggcc attcatagat accgctcaac aaccccatta aaatcacgaa
     7861 atagcaagca tacatcaata gctggaataa gactgttccc gcaggacgtc cgatataaaa
     7921 aactagtgta tagcgatgat tttcaatatc acggtcaaga tcccgcaaat tattagccaa
     7981 catgatattg gcaatcgtaa acaccaaggg taaggaagct aatacgattg ctgctatagc
     8041 ccaaagattt cctaccaaag caaattgtcc agatgaaaag ttgactgtca gatcatagac
     8101 atctgaaccg aatgtattga cataaacgac catggcaaaa attccaaggc ccatagtcac
     8161 cccactgaaa atttccccta aaggcattcg agataaagga atcggtccga atgtatagaa
     8221 tactccaata aaacaacaga taaatcccat caaaagtaaa agccaacccg tattgatcgt
     8281 tagaataacg ccgataacaa aaacaaatgc aatcatagct aaaatcatgt ttcgaatcaa
     8341 tacaggagat agatttctgc ggccaatgac attttcttca tacttatata cttcagaatg
     8401 agccttttca taatccatgt aattattgat agcggtagtc gctaaatcaa aaactagcat
     8461 tccaataaaa aataaaaaag tgtttagcca atgtatctca tgaaaaaaag cgatagagaa
     8521 taatacccct accgcaaaag gaaatacact agccaccttt gttcgtattt caactacttc
     8581 taaaaagatt tttagtgtca tggttcgtac tccttatttt agttcagaac ggtcacccat
     8641 cgtgtaatgg gagtcctccg ataatttgaa ggtgtctttg attggatcgg tcacatatac
     8701 tttatcgtct tttgtcacga agatcgcttc cgtcccgtta ttcaattcgc tttcgacgta
     8761 ttccagtcct tttttcacac ccattgaaaa gactgctgta gacaacccgt caccatcaat
     8821 tgatttatct gttatgatcg tgacacttgc gatatcattg tcgaacggat aacccgtttt
     8881 tggatcaaac aaatgatggt attttttgcc atctacttct aaataacgct cgtaaattcc
     8941 agaggtaact aatgttttgt tccgttcttt aatagaacct aaaacagatc cgcgagccat
     9001 gttcggatct tggatgccga ctgtccagtc ttggttttcg cctcttgggc tgtggcctaa
     9061 gacatagaca ttaccgccca agtcaacgat ggcagtggtc actccttgtt ttttcaagac
     9121 tttcactact tcgtccgtaa tgtaaccttt ggcgattgca cctaaatcga tgatcattcc
     9181 tttttctttt agataaacag ttttttcttt gtcatttagt tcgatcttat gataatccac
     9241 taatttcaat gcctgatcga tttcttcttg ggaaggtttt ctggcgtcat caaaaccgat
     9301 tcgccataat tgtgtgattg caccaatcgc catatcgaat ccgccttgag aatcttggct
     9361 atattcgtag gcccgcttga ctaacgtgta gacgtcatca gaaactttta ctggtttgat
     9421 cccagcttgc tcattcactt catcgatctc agaacctttt tgattgatcg tgattttatc
     9481 accaagttct tttactcgat cgaaggcagg tttcaatgct gattctttgc cttcatcata
     9541 cacacggata cgaacgtaag tccctaacaa gaactgttca tcagaatatg gatctttcaa
     9601 tatcttggta gctgctgaac tttcagtggt tgttttattt gctgagttgc tgcagccagt
     9661 tagcaccata aaagagatgc ccagtgtgat taaggaaaat agtagttttt tccgcattgt
     9721 tttcctctct tcattttgaa aggtgagacg actgcctaat ctggctatcg tcccaccctc
     9781 caacttttat tagtatgatt atgtgattat ttttctgtta cgatattatc tacttcgatt
     9841 gtttgagtgt cgcctttttc agctgcattc actaattgtt gtgcgtacat gatgaatgaa
     9901 tgtgagctgt gtgtagcacc tgtaacaact tctacatcag caggtgagcc atcttcttcg
     9961 cccattgctt tgacgaattc gtcgttcaga gtagggatgt aagtttttgg ttctgtaccg
    10021 ctttttgctt tcatattttc attatattct gtatcatctt gttttgattt accgtctttg
    10081 tcgatataat caaagtttga ttcagttact ttgccgccag caactgtcat ttcgaattgc
    10141 acacggtagc cgttagagta gttcttttct tcaagcttgt aagtgccgtc tttcaaatca
    10201 gcaccattgt cgatttcgat tgtatctgtg ttaccagctt gagcagcttg gatcaattgt
    10261 tgtgcgtagt tttggaagct ttcagatgag tgagtagctc cagttacgac ttccacaccg
    10321 cttgcgcttt gtgcttttaa gaattggtca ttcaactcag gaatgtattt ttctgggttt
    10381 gtgccagatt ttgcttccat gtttttgttg tattctgcat cttttgtttt tgattcgccg
    10441 ttttcattga cgttatcata ttttgattca gtgattttgc cgtcttttac aaccatttca
    10501 aagactgcgc ggtaaccgtt tgaataattt ttttcttcta atttatatgt gccgtcttgc
    10561 aagtctccgc cagcaacaac ttttgcagat gattctgttg tgctttttgc agtcgaagat
    10621 tgtgctgtag atgattcaga agaagagttt gagcttccgt tgtcatctgc gccgcaagcg
    10681 cctaacacta gagctgaaaa tgctaatacg gcaaatccag ttacaaaacg ttttttcttc
    10741 attttaatac cccaccattc catttttagt ccacaatttt tctttgtgat tcattataca
    10801 ttctaatctt tttagcctat aagtcaacta tttttgataa ataacccatg taatatttca
    10861 aacgttttct ttcagcaaat ttcgtgaaaa aacgctttat tttaaaattt gaaaaaaatc
    10921 caaaaggagt tagacaaaag aacagaacat ctatataata tatggagatt gtgtaataag
    10981 tatcaaacta aaagaattat catatattca ttatatagat agtctataag gagcggatga
    11041 tcaatggcaa agcaaaatat tgtcgttgta ggagcaggat atgccggtgt ttcagctaca
    11101 aaatacttgg caaagaaact gaaaaaagaa gatgtagcaa ttactctgat cgatcgtcat
    11161 tcgtaccata ctatgatgac cgagttgcat gaagtagctg gcggacgtgt agaaccagaa
    11221 gcaatccaat acgatctgca gcatttgttt gctcgtcaaa agaatgtaca acttgtcaca
    11281 gacactgtaa tcggtatcga taaagaacag aaaatcgtca agaccaaatt aggttcctat
    11341 ccttttgatc agctgatcct tggaatgggc ggagagccga atgactttgg tacacctggt
    11401 gtcaaagcac atggattcac cctttggtca tttgaagatt ctgtaaggat tcgggaacat
    11461 attgagaaga cagtagcaaa agctgcattg gaaccagatg atgaactgcg taaagccatg
    11521 ctgactttcg ttgtctgtgg ttctggattt accggtattg aaatgattgg ggaactgatc
    11581 gactggaaaa atcgcctagc caaagattat aagttggatc caaacgaaat cacactgatg
    11641 gtcgtagagg caatgccgac gatcttgaat atgttggatc gaaatgatgc tgcaaaagct
    11701 gaacgctatt tgcgtaagca caacgtggaa ttattattga atgcaccaat cgtagaagtg
    11761 gctgctgatc atatcaaatt gaaagacgga cgcaacattc cgactcacac actgatttgg
    11821 acagctggtg tcaaaggaac gtctgacgct gctgactttg gattagaatc agcacgcgga
    11881 cagcggttga tcgccaatga atatatgcag gcaaaaggct acgaagataa aaacatctat
    11941 atcattggtg atttagtctt ttatgaagaa ttcccaggaa caccgacacc gcagatcgtt
    12001 caagctgctg aacaaacagg acacacggct gcagcgaata tcgtggcttc gatcaaaggt
    12061 ggagaaaagc acaaattcaa agggaactat caaggattta tggtttctat tggagccaaa
    12121 tggggtgtgg cgaatttatt tgacaagatt catctaagtg gatttttagc tatcgtgatg
    12181 aaacatatcg ttaatttgaa atatttcttt gatattcgtt ctggttatta tatgttccaa
    12241 tatttaatgc atgagttttt ccatatcaaa gatgatcgca acgtgactcg aggacattct
    12301 tctcgttacg gcaacgtctt atggagtgtg ccacttcgta ttttctatgg tttagtttgg
    12361 ttcgttgaag cctccaaaaa aatcattggt aatggtgaag tgttaaaacc aagtacttgg
    12421 tttggtgaag gatcatggtt cactggaaac agtgtgttcc cttggacatg ggaatacaat
    12481 gtaacagatg ttgccagtgg tgcttctgct gctggtgatg caaccacagc tgccagcgga
    12541 gcaggggcaa gtgccggaga agcagcgact caagctgcac attttggttt gagttatgca
    12601 tacggtgaag aaccaatggc tgtgattgag aagtcaccag actggttcac aaagatcatg
    12661 caagtgatca tgccaaacaa tgacgtagca atgttcttcc aaaaattcat ggtattcttt
    12721 gaaattgcct tggcattagc attgattgct ggattattca catggctatg cagtgcgaca
    12781 acgattgtat tggtgatcac gttctgctta tcaggcatgt tttactgggt aaacatttgg
    12841 ttcatttttg ttgctttcgc attgatgaac ggttccggac gtgcgattgg gttggatcgc
    12901 tgggtaattc catggctaca acgtacacta ggtaattggt ggtacggtag accaagttcc
    12961 cagtacggca agaaataaat agataaagaa cgttatttga atgcaagatt tcaatagaaa
    13021 ggggctgaga caaaccgtca cagcctcctt tttatgtaaa attaaaggaa taagatgccc
    13081 gagataagcc tccatgagca agacacaggt gtcgcaacct ctgttacaac ctcttgttat
    13141 aaacggtgtt ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaacttgaa
    13201 aagtaatttt cgtaaattcc ttcttatttc ttgaagttgc ccacttctgt cacaacctct
    13261 tgttataaac ggtgttccac ctgctgcttc tcggtaataa gcccaaagaa ttagaaaaca
    13321 tggaaagctg ttttctattc ttcgttctta ttactcaaag caagacacag gtgtcacaac
    13381 ctcttgtttt tatgctaaaa ttgggtgagt taatctggaa aaaggagaac aaaaatgagc
    13441 cttaaagaat ttgctgaaaa aagtctgctc aaaccttggg atgtttttat aatttttctt
    13501 ttgactgttc tttctttttt gccagtcatg atttttggtc ttcagcaaaa caccgtaaca
    13561 gcagaaaaag aagcggtact gcgtgtggat ggcacagaaa tcaaaacatt ccctttgatg
    13621 gctggagaag agagctacac atatacttac aaagatgaac acggagatta taacttgatc
    13681 gagatagatg gcgatcgagt acggataaaa gaagcagatt gcgatgacca gatctgcgta
    13741 cgtcgaggct gggcaacgaa aaatggcgaa accattgttt gtttaccaca taaattagtg
    13801 atcgaggtcc gatcaacaga tgggggtgac gaagacagtc tgatttatta gaccttcaca
    13861 caccatgagt aaattacaaa aaatgattta tatttcgcta cttgttgcac aaggagtgat
    13921 cattggttta ttggaaaata tgatccctta tcctttttct tttgcgcctg gtgcaaaact
    13981 aggcttagcc aatctaatca cgatcgttgc catttttacc atgaaaaaac gagacagctt
    14041 cttactactt tggctacgac tattcctgac tactctgcta ggcggaacga tttccacatt
    14101 cctttatagt atgagtggtg ctttgcttag ttattttgga atgttattgg tcaagcaatt
    14161 aggaccaaaa cgtgtcagta tcatcggaat tagtgcggcc ggcggtttca tgcataatgt
    14221 cggacagctt ttgatggctt ctttcattgc acaatcatgg acagtcatgt tgtacttgcc
    14281 agtcctttca gttttaggga ttttatcagg gattgcaatc gggatcgcag cgaattatct
    14341 tttacgacat gtgcagacac ttcaacgatt ccaaaaagat tatgagcagg gaaccaaaca
    14401 aaaatggagc ccaatgttta ccaaaaaata atcgtcacac aaggagtttt tttatgaagc
    14461 tacatccaat gtgggaaaac tatcctgctt taagtaaaga attgacagaa acactaaaac
    14521 ggatggaaga aactgtccgc ctgaaaaaca aacctgtcga acaagcaatc aaagaaacga
    14581 tccatgccgg cggaaagctg ttgcgtcctg cctatcagct attgttctca caatttggac
    14641 cagagcaaga tcgagacaaa gccatcgctt tggcagcttc tatcgaaatg ctccatacgg
    14701 ccacactgat ccatgatgat atcgttgatg aagcggatct gcgacgtggt cagcctaata
    14761 tccgtagtca gtttggtaat gtcgtttctg tctatgcagg agactattta tttgtctgct
    14821 gttttaaact attgtctgat tactccactt ccttgaaaag tctccaattg aattctcgca
    14881 gtatggaaaa agtattgaat ggcgaattag ggcagatgga tgatcgctat aattatgaac
    14941 tttctgtaaa agaatatttg gaaaatattt caggtaagac agctgaactg ttccaattaa
    15001 gttgttctat tggcgctttt gaaagtggaa caagcgagcg cttcgcaaaa aaagcaggag
    15061 atatcggact ttctatcggg atggcctttc agattatcga tgatatttta gattatacaa
    15121 aagagagcca ggaaatcggc aaacctgtac tagaagacat gcgtcaaggg gtctattctt
    15181 taccgttgat ctactctttg caaaaaaaca aaccaaagct actaccttat ttagagaaga
    15241 aagcggcaat gacagaagaa gatgtcgacg ccgtacgcaa aatcgttgaa catacaggag
    15301 gcgtggaaga agctaggaag ttagcggctt cttacacaga aaaggctttg aaggaaataa
    15361 agaaattacc tgccacctct cttcgaacaa aagagaatct cttttccctt acccaactga
    15421 ttttggatcg caaagactga atagggaaag gttcgatacg taaataaatt tctcagaagg
    15481 aaatctacgt gttttttgac aaattgaatt gtagttcttg tatttatgat aaaaagcaaa
    15541 aataaagagc aacgtccgtt agcgacgttg ctctttttta tcttgaatat ttttttacct
    15601 tttcgatttc ttataactca taaaagtgat tcttaaaccg attacaagta atataacgcc
    15661 tgcgagtgtt atccaattat tcgattgact tccagtttta ggaagtgctc tttttgattt
    15721 gtttccattg tcattgcttg ttttattagt taagttaaag ttcgtcctgt tatccgaact
    15781 tgtttttgag aaggagacac ttgcatgacg tgtatcgctt gtggtagacg acgtgtctgt
    15841 actatcgctt gaagttgatg aatctgagct atcacttgtg gtagagattg tatctgtact
    15901 gtcgcttgaa gctgacgtgt ccgtgctatc acttgtagtg gtagatgaat ctgagctgtc
    15961 gcttgtggtt ttagtacctg tactgtcact tgaagctgat gtgtccgtgc tatcacttgt
    16021 agtggtagat gaatctgtac tgtcacttga agctgatgtg tccgtgctat cacttgtggt
    16081 agaggtagta tctgtactat cgcttgaagt tgatgaatct gagctatcac ttgtggtaga
    16141 ggtagtatct gtactgtcgc ttgaagctga cgtgtccgtg ctatcacttg tagtggtagt
    16201 tgaatctgag ctgtcgcttg aagctgacgt gtccgtgcta tcacttgtag tggtagttga
    16261 atctgagct
//
LOCUS       DADVXB010000060        16129 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.061, whole genome shotgun sequence.
ACCESSION   DADVXB010000060 DADVXB010000000
VERSION     DADVXB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.061"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(260..763)
                     /locus_tag="KB902_001503"
     CDS             complement(260..763)
                     /locus_tag="KB902_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6808338.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDVITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1123..2148
                     /locus_tag="KB902_001504"
     CDS             1123..2148
                     /locus_tag="KB902_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6808339.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRSEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2471..3349
                     /locus_tag="KB902_001505"
     CDS             2471..3349
                     /locus_tag="KB902_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBB6808340.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDKQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKKQ
                     LLAGEHIGSGLGILTS"
     gene            3779..3895
                     /locus_tag="KB902_001506"
     CDS             3779..3895
                     /locus_tag="KB902_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6808341.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            complement(4398..5600)
                     /locus_tag="KB902_001507"
     CDS             complement(4398..5600)
                     /locus_tag="KB902_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6808342.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPYYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFVMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDGDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(5603..5797)
                     /locus_tag="KB902_001508"
     CDS             complement(5603..5797)
                     /locus_tag="KB902_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6808343.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(5844..6692)
                     /locus_tag="KB902_001509"
     CDS             complement(5844..6692)
                     /locus_tag="KB902_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBB6808344.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDVLYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(6897..7247)
                     /locus_tag="KB902_001510"
     CDS             complement(6897..7247)
                     /locus_tag="KB902_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808345.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELPQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            7842..8288
                     /locus_tag="KB902_001511"
     CDS             7842..8288
                     /locus_tag="KB902_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6808346.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAGTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            8931..9902
                     /locus_tag="KB902_001512"
     CDS             8931..9902
                     /locus_tag="KB902_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6808347.1"
                     /translation="MEKTLGPGGEIRAEQRDNKNISKWKKLKKQLRRDKWMYLLLLPG
                     IIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLLLSNTLKI
                     SIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLFLFLSANG
                     PINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVSTDLYEAA
                     NIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNIPASEIIS
                     TYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            9918..10802
                     /locus_tag="KB902_001513"
     CDS             9918..10802
                     /locus_tag="KB902_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6808348.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTTQGYQRVLADDSILRGFINSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            10851..12458
                     /locus_tag="KB902_001514"
     CDS             10851..12458
                     /locus_tag="KB902_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6808349.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSTSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFVEKRNLDIASGDLP
                     DAIFNAAASDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SLPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLRVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTITTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            12459..13943
                     /locus_tag="KB902_001515"
     CDS             12459..13943
                     /locus_tag="KB902_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBB6808350.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPVGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYNGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDAYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTTEPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            14120..15112
                     /locus_tag="KB902_001516"
     CDS             14120..15112
                     /locus_tag="KB902_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6808351.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPNIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGGTTKSLVRNDFA"
     gene            15164..16033
                     /locus_tag="KB902_001517"
     CDS             15164..16033
                     /locus_tag="KB902_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6808352.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMKQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGRIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQAFKEKMGSYVDTPTLEEYLLTPMLADNAGL
                     IGCLALAIKKLNH"
BASE COUNT         5072 a         2633 c         3243 g         5181 t
ORIGIN      
        1 aaattaagac ggaattcctt tctagattga gatattgact agggagaatg ttaagatttt
       61 aagcctttaa gctaaaaaaa accctttttg ttaaataagg ggaatatagc ctgtcagttt
      121 caaactgcaa gtcgtcctgc tgcaataata tagtagatta gagatgaaaa tagatttttt
      181 taaaccaatg actgaataaa aagaccgtca tagatacaca ttggaatgtg tctattacgg
      241 tcttttttta cgaacgattt tattgaagac ggacagttcg ggtcaaaaat aaaaaagcta
      301 cgatcagaaa taagaataaa atgtatccca aaataatggc tagacggtct aacttatttg
      361 tcgatagatg tttgtttaga agctgatagg cccataaacc tatcagtcct cctgttgtat
      421 tagtaattac atcagtgata tccgctacgc caataccgaa taggaattga atcaattctg
      481 ccaagaagct tacaaggaaa ataatcccta attttttaga aaaagaaagt ctcttgaaat
      541 tgacattcaa aagcacccca aaaggaaaaa agacaatcaa gttataagtg gtctcacgta
      601 ataccgtcgt attttcaaaa gaaaaagtag aaaaagggac gagattgaca ttgctgtaag
      661 aataagtgag gaattgtgga agattaaatg atagcttgaa taaaatcaac cataatagaa
      721 agaataaata aatccctaat aaaaattttg atacataccg catagacatc tcctccattt
      781 aaaaagtata ccatcgaaaa ccgttgaaaa atcataaaaa agtatgaagt ttaaggacca
      841 acgtagttat cgtacgaaaa ttagaagctt tttttttgtt gggaatccgg tttctttaac
      901 aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca aaacgactcg
      961 gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac taagtttatg
     1021 aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg gcatttcatc
     1081 ttggttcagc tttttttcca attactagga aggagggata gattgttcaa gacttatttt
     1141 cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct acttatcttt
     1201 attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt ttcatcatta
     1261 gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct gaaacgtatg
     1321 tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc gacttatgtt
     1381 ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt tgtgttgcga
     1441 ttattccata tctctaaacc aggtggcttg ttttttgcga tgctttctgc catgggaacg
     1501 agcatgcagc tgccaatcgc tcaattaccg atcgtctcgc tttatttttt tatgggtgtc
     1561 gtttttgccc tgattgcggc agtgattaca aaactactgg attcacggtc tgagcagaca
     1621 attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat cattgattct
     1681 gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt gaatctgcat
     1741 aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg
     1801 atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg tgtgtcggca
     1861 ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac ttttctatat
     1921 ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt tcttaatccg
     1981 atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt gatcgaatat
     2041 cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg
     2101 gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat
     2161 atgtgccaaa agaggttatg acaagatttt tgttacaacc tctaattcaa ggtgttcaaa
     2221 agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa
     2281 aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct
     2341 gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa
     2401 gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt
     2461 catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa
     2521 tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat
     2581 tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga
     2641 tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt
     2701 tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc
     2761 attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca
     2821 tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta
     2881 cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa
     2941 agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga
     3001 tgcagactta tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga
     3061 actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc
     3121 caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg
     3181 attattatca gttgataaac aggacgatag tggagtccct tggatctttg gacgagtaga
     3241 tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa aaaagcaatt
     3301 gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag tttagtagtt
     3361 tagtacttcg aaatagttta aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     3421 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa
     3481 acgcttctgt cccagcctct tttttagtgt tctatcgaac aaacagtacg ttcaataggt
     3541 aaactagcta taacaataga tattaaagtt aacggacaag agggcctttt ttaggtagct
     3601 aaaacgtaat aatgaaaatt tatttctaga gataggagtc aatcagctag tctgatcgac
     3661 tgttttaaca agttgacttt ctttttaact tttgatacca tttaaaacgc aaatcgtaat
     3721 tgtttcgatt tgtgtttttt agcatgacta caatcaaaga agaaagtggg tcgtccatat
     3781 ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa agtccaaata tcaaaacacg
     3841 aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat agtgggaaaa ggtaagaaga
     3901 aggaaactta attaaaaaaa tagccgaaaa acgtttttcg gctattttca ataatcggtt
     3961 tttgtgtaag gtttccgaaa gaactgctgt tgattttcca tttttaacat atgataaatt
     4021 ggtagaatct ttcttttcaa tttgatacca ttccctaatt ccagttatat agttaactac
     4081 agaaccacaa agcacgtatg tttataaaag tattatctgt agttattttt caattccctt
     4141 tcaacctctt attttgacca gtagtattga tcactttacc ttttaacacc tttgttcgtt
     4201 ttggaaacat ttttagttcc attctgtcac gatagaaggt tggttacaaa aataaaaaaa
     4261 gaaccgcgaa tcccttgatt atcaaaggat tcacggtttc ttttattatt cccactcaat
     4321 atgagtagcc tcgtaaagaa gctattatat cagtgctttt tcagcctatt cctcattttg
     4381 gtagggaaat ggtagggtta gatttttact gcttgatttc cattaaagtt tgcaacttta
     4441 gattttgttg cacaggtaaa tttaatgttt cctgtcattt gttctgcaat tccttcatca
     4501 ttacggctcc atagatgagc gtagtgcttt aaagtgattt cagggctaga atggcctaac
     4561 cgttgcgaca cgaccagaat gtctgcgtta aactcattga ttaggtagct aacatgagaa
     4621 tgacgtaatc cttttccttg tattaggggt accttagcta gtttggcata acgctgaata
     4681 attcgttgaa cagttgaacg atagagtggg aggtcagtgt agctaagaat aaattgttct
     4741 acaccatgat ttttttgaat aactttccac ttttttagca cttcaattgt atcaccgtcc
     4801 agagaaatga tccgcaagcc gctttcagtt tttgtgtaag gtttccgaat aaaatctttt
     4861 tgatttgtca tttccaaggt gtgatgaacc ctcaactttt tacgtttgaa gtccacgtca
     4921 ttccaattaa gtgctaatcc ttcgcttaca cgaacaccag tcatgtaata tagccaaatc
     4981 attacaaaac acatatgttc gtagaaatca tctttataaa tttttgccaa aacttcttca
     5041 aattcttctt ttgtccagta aggaacgatt gattttcctt ttggaattgc ttttgttctt
     5101 ttggaaatat tctcattcag aaattgcagg gtgaccgcat agtctaatga tttacgaaac
     5161 ataccgtaca taagtgaact gtatgcttgt gagtatccgc tatcgttcaa taaccaaatt
     5221 cgataatttt cacaatctcg cacattgatt tcacgaagct tcttatcacc gaaaaattca
     5281 gtaatctgaa tcaatccaca ctcacgagaa ctccaagtac ttttttgtac gctagctttg
     5341 tagtatggaa cgtaagactg ctccataaat tctttgtaag ttaaatcata attcgcaaat
     5401 ccatttacaa ccatgtattc attttttata cgcatgactt ctttgtgtgc ttcacgagct
     5461 gatgagaatc gttttcctag agaatctttt gttcctttct tctggatcct ctttccagtc
     5521 acttgatctg ttcctaactc aactagataa gaaaagcgac catttttatc ttgatacaca
     5581 caagggtatt ttgttttcat agttattcct cctgtgaaag aggaacacct ataatttctt
     5641 caattacttg tctgggtaca accccaactc ttttattatt ataatatgga tatccctgat
     5701 ttaccattct tgtttttgct tgtcggatta ttgtggtagc ttgatgtgtt ttaaatccta
     5761 gagcctctaa atcttttcga caaattgtat ttttcattgt ataaactcac tttcaaagaa
     5821 aacactatca ttgggtaata gtgttatttc tttatttttg tataatgaac ggtactttct
     5881 tgaaaatcca tcacttgttc aggacttccc aactcattta aagctaaagc attgtaaaaa
     5941 aatggacgtc taactatata ttcgcttgta tatagtacat cttgattcgt ggaatcatag
     6001 ggtttcttta ccatcttttt ggtgacagtt ggtagtttga gattccggga cttgaaaaaa
     6061 gcttttttct tatgctcttt caattccagc tctttatcga aatatttgct gatatagcgc
     6121 ccgcgatttt cgatactgtc tacatcgatc ttgttgatct taacgaaacc ctgaccccaa
     6181 atcgtagtta accggttaaa tgagataaag gggaaatcaa acaagataat atggtagtgg
     6241 attgcaccgc gttgctgctt ttcccacgtg gcgagatact ttaaatttgc ttttttagtt
     6301 ttatagaggt cataattcag tcgtttgata aattttttaa attcattatt tgcatactca
     6361 atgtcttgaa tgttttcttt gaaagtgaga gttaaaaatt tcgtttgatt gtcaaaattc
     6421 gtgtctacaa ggcgggcaat ctcaaatcgc atactttgat aatgtttctg tttgcgtttt
     6481 aaactgtcat attgtccttg agcggataat tcatcatagt tttttctttt ttcaagagta
     6541 atatcatttt cataaatcca agctaatttt tgttttcgtt ccagatttac ttcgttttcg
     6601 atcgttttac gtttgggagt aatgattgct tcataatcat aaatttcaat gtacgtggga
     6661 gtttcaatga ttttctgatt ataagcttgc aaaaatcatc actccttgtt gcgtattcga
     6721 ttgtcaaaga accagtcatt ttctcctgat gttgttctat aaatcaagtt aagggggaag
     6781 gcctgcgtgg cagcccttct agcctatggg gtgttgggcg gtcttaacgg acagaaacgg
     6841 ctctgtgggc gctgccccgc cgtttcgtcc taaccaccca acactccata gtatagttag
     6901 ttttgtgtag tggtaccttg ttttctggga atcaaagttg ccgtatcagc ggttgccgat
     6961 aacccataac tgacaaattg tccattcgag cgtccccaag gtacaatcac caaattggta
     7021 aatgtaatta tggctaaacc ttgttgggga agttcttccg gcgtgatcac aggatgttca
     7081 gatttgactt tgacactgat tttttcgtag cgaagttttg gtaggataca ttcgtagctc
     7141 caacctagaa tttcgccctc cttttgccag cgagtgacat tgacgacttg gtattctttt
     7201 tcgagtgttt cttttggtaa actgagatcg gtaattttta ttggcatcac aattctcctt
     7261 ttttatacga aagtttatac gatttgatta aaaaatatag atgaccatct acgacttgta
     7321 ttatatacga gaacttatac gtagtcaaga gattttctga aaaaatatat acgatttttt
     7381 atacgagtgt tataatgaaa aaaatgataa ggaggaattt gaatatgttt ggtttagtac
     7441 aacctaataa agtgaaggtg ggccaacgaa tcaaagaaat aaaagacgga atgtctctct
     7501 cttttacaga attagggaat cgattaggtt taaaaaagcc gacgatcagt tcctacgttc
     7561 aaggctatgc gttggctcct aagagtgtga tcaaccaatt atctagtatc agcggaaaac
     7621 ctgtcggctg gttttatttt gggcatgtgg aagaatatat ccgagagtat ttgtttctca
     7681 ttggtcagaa acaaatagtg gacgattatc ctgaaatcat tgagaaaata aagcaagaat
     7741 tttatacggg cgagttcaaa aatcctgctt gggagaatga gctaggctat cctttggagg
     7801 aatttatcca agaatgtttt gtagaatatt cgagtgaaat catgaaggac tatgtcgtac
     7861 agattacgaa agaggtactt gaagaatcca aaacgctaaa caaactatca tcaaaagcaa
     7921 aagaagaagc tggcacgatt ctttcatctg ggatcattga ctatatcgag atgagtggtg
     7981 agatcaagta tggagagaaa gatcgcattg cgaaaatggt gaaagaatca ataaaaacct
     8041 ttgatgtgaa acaagacctg acatttaatg attcctattt gattggaaag ttgatcaata
     8101 ttcttggtac agatgaagat acggagctat ttctttcttc tttatcaatg atatttactg
     8161 ataagcattt ttccactcga tttggtgggg aagaattagt cgaaatattt caatcgatgc
     8221 gaccagcgtt aatcaaactc tatcgggaga aaacaccaga tgaattttat gattggtttg
     8281 agaagtaaaa taagaaaagt ggcttagatt acaagttggt gaaaaaattt ttttcagcgt
     8341 aacatcagta atctataaag gggttgttga ttatactgta gaagttaagt actcaagaga
     8401 ttttttgtac gtaaacaaag caaaaaaggg tgcagtttca ctagaaaatg tactcttttt
     8461 tgtgattttt cttagttata gagttttttt gaaactttaa aaatgagaaa acatattgat
     8521 tttaaagagt gtagacatag cttcttttgc taaatagatt aaacttactg gtgagtggtc
     8581 ttgaacatac ttttaaatca cattttactg agttttattg gattttataa ttcattggaa
     8641 acctcgtact taatctgttt ttatctatcg actagaatct gtatatattc tagctatcaa
     8701 tgaggccgca gaaaagggtg cttaaaaata atctgttgtt taaaatatta ttatcagaat
     8761 acttagatac aaaattctga cacaaagtaa aaaaaatatt gacttaaaaa aattactgtg
     8821 gtaatctata aacgaaaata atggaaacgt ttccgaaaaa cgtctttgtt ggatttttat
     8881 tttttaaaca aaaatggaaa cgtttctaaa attgttggga ggagattgaa ttggaaaaga
     8941 cattgggacc aggtggtgag ataagggcag aacaacggga taacaaaaac atctcgaagt
     9001 ggaaaaaatt aaagaaacag ttgcggcgtg ataagtggat gtacttgttg ctcttaccag
     9061 gtatcatcat gacgtttatc tttaagtatg taccaatgta cggtgctgtg attgcattta
     9121 aagactataa tcctatgcta ggaattttgg aaagtccttg ggtaggacta gatcacttta
     9181 gggaatttat cagttcacca aattttacgc ttttgctgag caacacatta aaaattagca
     9241 tttatggttt attgttaggt ttttttccac caattatttt agcactgagc ttgaatcaaa
     9301 ttatcaataa aaaaataaaa cagaaaatcc agttgattct atatgcgccg aattttatct
     9361 cagtagttat tatcgtgggg atgctgtttt tgttcctatc cgcaaatgga cctattaatg
     9421 ggttagtaga aaaggttacg gggcaaccaa ttatgttcat gtctaatcca gcttatttca
     9481 gaacgattta tattttatcg ggaatttggc aaggaatcgg ctggtcatcc attctttaca
     9541 ccgcaacact ggcgggagtc agtaccgatt tatatgaggc agcaaatatc gatggggcaa
     9601 atattttaca aaagatttgg catatcgatt tgcctgcatt gaggcctgtg atggtgatca
     9661 gcttcatctt ggccgccggt ggtattatga atgtaggata tgaaaaagcc tacttgatgc
     9721 aaacttcaat gaacatccct gcctcagaaa tcatttccac ttatgtatac aaagtcggct
     9781 tgcaatcagg tgattatgcc tactctgctg ctgttggtct gttcaatatg attattaatg
     9841 tcgttttatt actgattgtc aacaatataa ccaagcggct aaacgatggt caaggcttgt
     9901 aatgaaagga gaaaattatg aatagtgctt tatcaaaaat cgaccgtcaa atcttatggt
     9961 tgaatcgagt gattgtaact tttttagtcg tcatcaccat tgttccgctg atttatgtac
    10021 tggtagcttc ttttatggac ccagctactt tgatcaataa aggtataagc ttcaatccga
    10081 aagattggac aacacaagga tatcagcggg tacttgcaga tgactccatt ttacgcggtt
    10141 ttataaattc gttgttttac tcttttagct tcagcttatt gactgtattt attacgatga
    10201 tcactgcgta tcctttgtct cgacctaact tggctgggaa aaagattatt atgacttttt
    10261 ttgtcattac aatgttcgtt ggtggcggct tgatacctac ctatttattg gtaaagaact
    10321 tgggcatgtt agatagtgta tgggcgatta tcgtaccagg tgctataaat gtgtggaata
    10381 ttatcttagc ccgtacctat tttagtgctt tacccaaaga actttctgaa gctgctacta
    10441 tcgatggggc caatgatttg caaatactgt tcaaagtcat gcttccatta gctaaaccaa
    10501 ttatgttcgt gttgtttcta tatgcctttg ttggacaatg gaattcatac tttgacgcca
    10561 tgatctatat taaagatccc gacttacagc cgttgcaact cgtattaaga aatattttga
    10621 tccaaaacca accctcacaa gacatggtgg gagccaatac agccatggca gaaatgaaac
    10681 aaattgctga gttgatcaaa tacgcaacga tcgtcatttc tagtctgcca ttaatcataa
    10741 tgtatccttt cttccaaaaa tattttgata aaggtgtttt agttggttct gttaaagggt
    10801 aagaattgtt cactatttgt atgaataaaa attataaagg agattttaag atgaaagcaa
    10861 aatggatgct gccaatcgtt tttacttccg tactaatttt gggggcttgt ggaggctcaa
    10921 aagaaaagag tacatcaagc cctgattatg aactagaaaa tgtctctttt ccattgaaag
    10981 aaaaagtatc tttaaaaatg atgtctcaaa gtgccccttt ggctcccaat gatcctaatg
    11041 acaaattgat tttccaacgg ttagaagaag agaccaatct ccatattgat tggacaaact
    11101 acagtagtga ttttgtcgaa aaaagaaatt tagatatcgc tagtggggac ttaccagatg
    11161 ccatcttcaa cgccgctgca agtgactatg atttattaaa ctgggcggaa agtggcgtta
    11221 ttgtaccgat tgaagatttg atcgaagatt atatgccaaa tctgaagaaa atttttgatg
    11281 aaaatcccga ataccgacaa atgtctactg cacctgatgg tcacatttac tctctgcctt
    11341 ggattgaaga attaggggaa ggaaaagagt cgatccatac agtgaatggg atggcttgga
    11401 tcaacaagga gtggttggat aatttgggtc ttgaaatgcc gcaaaccacc gatcagttga
    11461 tgactgtgtt ggaggctttc aagacgcaag atccaaatgg taatggtgaa gcagatgaaa
    11521 ttccttttag ctttattaac aatggaggaa atgaagactt aaaattttta atgggggcat
    11581 tcggtctagg tgataatgat gaccacttag tcgttgataa cgatggccag gtacaattta
    11641 ctgctaacaa agaagggtat aaagaagcca tcaaatattt caatgaaatg aataataaag
    11701 gtcttattga taaagaggct ttcgaacaag attggaatac gtatgttgcc aaagggaaag
    11761 aacataagta tggcgtgtac tttacttggg ataaagcaaa tatcacgggt gcagatgata
    11821 gttatgacgt cttgcgagtc ttagcgggac cagatggaac gaaacacgtt actcgtacga
    11881 atggcatggg tttctcaaga gatcgtttcg taattactag tgcgaataaa aacttggaac
    11941 ttacagctag gtggatagat aaaatgtatg aaccgttaca gtctgtccaa aataactggg
    12001 gaacctacgg tgatgaagca caggccaata tttttgaatt aaaggatggt atgttaaaac
    12061 atttgccttt agaggggaca gcaccggggg aactaagaca aaaaaccgaa gctggaggac
    12121 cattagcagt tcttgattcc tattacggca caatcactac tatgccagat gatgcgaagt
    12181 ggcgtttaga tttgatgcat gacacgtatt tgccatatat tacagaagac aatatctatc
    12241 cacgtgtctt tttagaaaaa gaagaaacag atcgattagc aaaaattgaa acagatatgt
    12301 gggattacat ctatcgcaaa agagcagagt ggatcaccgg cggtaaaatc gatgaagaat
    12361 gggaagaata ccttgctgaa ttggaacgtg taggtttgga agaatggatt caaataaaac
    12421 aaactggcta tgataatttt ttgaagggag cacaataagt gttagtagaa gaaacggcga
    12481 ttttggataa agcaaatcga tttattgaaa tgatgcgagg aaaagttaac cctcagtatc
    12541 gacaaaacta tcatttttcc gcacccgtcg ggtggataaa tgaccccaat gggtttatat
    12601 attacaaagg gcattaccat ctcttctatc aatactatcc ttacgatagt cgatgggggc
    12661 ctatgcattg gggacatgcg cgcagtagtg atttggtcca ttgggaagat ctaccagtag
    12721 cgttagcccc agatcaacct tatgatagtg gcgggtgttt ctcaggaagt gcaattgaaa
    12781 gagacggaaa actatattta ttttatacag ggtgccaaga aattgatggt attagccatc
    12841 agcatcaatg tttggcggtc tctgaagatg gtattcattt tagcaaatac aatggtaatc
    12901 ctgtggtagc agaaaaacaa ctaggtgaaa atgggctgat acaagaattt cgtgatccta
    12961 aagtaattgt tcacaacgat gcttactata tggtagtagc tactaaatct acacagtcta
    13021 ctggtagaat agtgatgttt caatcgtcag atttgtatac ttggcacttt tactctgtgt
    13081 tgctagaagg gacttcagag caaggaataa tgtgggaatg tcctgattta ttccatttag
    13141 acggacgaga tgtcttaatc atgtcaccga tacaaatcaa gaagaacgga ctggaatatc
    13201 ataatatcag ttctaccatg gcttgtattg gtgaggtaaa ctgggaaaca ggtcagatga
    13261 tagttgataa tttccatgaa atggattttg gaatggattt ttatgcacca caaacaacaa
    13321 cagaacctaa tggtggacgg gtgatgattg cttggatgca gatgtgggat cgtacattgc
    13381 ctacacatga gttaggccat ctttgggcag gctctatgag tttgccccga gagttaagag
    13441 taaaaaaaaa tcgattggta caaaaaccca tctcaactgt atatagtcat ttagtttatc
    13501 aacaaggcag tgaaaatatc gcagtgactg acacatcagt cgtatttcga aacgcactgt
    13561 cggattcttc atatttacat ctagtcgcag atttggagaa agcagaagtt tttacaattg
    13621 aattactgcg gtctaagacg gattgtctca aactagccta tgacactgct acacaggttt
    13681 ttgaattgga tcgtcagaaa ctaggaagag agcttacagg ggcggaagaa gaccctctga
    13741 atgtccgaaa agttgaagta cctttgattg ataatcagct cgttcttgag atttttagag
    13801 atacctcatc aattgaagtc tttattaatg ggttagaagt tatgacggct actttctatg
    13861 agctggaaaa agctcgagat atcttgtttc attcgatcgg agaaagtcgt attcaagctt
    13921 ttgaaacagc gagtgtgaaa taaatgtttg attgcttagg cgatgaatca attatttaat
    13981 aggttttgaa ggataatgtt tttagaaaag aacagatagc tagatttccc atggatttgc
    14041 tattagtatt ttgaaaaaat tagtaattta tgacaaaatt cattatacta aacttgtgca
    14101 gaaatgtgag ggatcaacta tgaaagcaac aatgaaagat gtcgcaaaat tagcaggtgt
    14161 cggagtagga actgtttccc gggtattgaa taacggctct gttaaagctt ctactagaga
    14221 aaaagttgaa gcagcaatga cagagttaaa ctatcaacca gatttttatg cccgggggtt
    14281 aaagatgaag catacgaaca cggttgcttt gattctaccc acggtatggc atccattttt
    14341 tggcgaattt gcctaccatg tagaaacagc attagaaaga caaaactaca agctttattt
    14401 gtgtaactcc agtggtaata gtgaaaaaga acaagaatat atccagatgg tcagccaaaa
    14461 taaagtagac ggcatcattg gaattactta ttcagatatc gatgaataca tttcgagtaa
    14521 tctgcctttt gttagtattg accgttattt cactgaagag gtgatttatg tgaccgctga
    14581 caatgcggca ggtggacgtt tggctgcaaa tgaactttat cgccgaggat gtcagaatgt
    14641 agcatatatc ggtgggtacc aagaaacacc gaatgaaacg aagagtcgtc gaaaatattt
    14701 tgagatcgag tgccgtcaac tggggatttc ctataaagcg ttagatatgt tagaaccttt
    14761 agaccatctc tcagaacgtg taacaaattt tttgttagag aatcccaata tcgatgggat
    14821 ttttacgatc aacgatccaa tggcattagc tgtcattgat atgcttgaaa aaatagggaa
    14881 aaacgtacca gaggatgtcc aagttatcgg atttgatggt caaaagatga cagaaggaga
    14941 tccttatcta gtctcaacga ttgcccaacc tacaaagcaa atggcggaag tggcagtggc
    15001 aaaattaatt gctgtcatta atggagagac agtagaaaaa cgtaccgtat tgccgattga
    15061 atttggtgaa ggtgggacaa cgaaatcttt agtgagaaac gattttgctt agtgcaaata
    15121 cgtttctttt tttgaaaatg agtgaatgaa aggtgtagat aaaatgttat atggtggaat
    15181 agaagctggt ggaacaaagt ttgtctgtgg gattggtaat gaacaattac aagtgataga
    15241 acggaaaagt tttcctacta caacaccaga agaaacgatg aagcaagtgt ttgacttctt
    15301 tgataagtac aaaggaaata tcgcatcaat tggtgtagga gcatttgggc ctattgatat
    15361 tcaaatcgaa tcaagaactt acggatatat caccaacact ccgaagttag cttggcaaaa
    15421 ttatcatttt gtcggagctt tggaaaatgc cttgtcggtt cccatctatt ggactaccga
    15481 tgtaaatgct gcttgttatg gagaatatat ggcagggtat ggaaaaggta aaaatagtgt
    15541 tctgtattac accgttggta ctggtgttgg tggtggtgct gtagtggatg ggagaatagt
    15601 cgcaggtttt agtcatcctg aaatgggaca tatgctctta caacgtcata atgaagatca
    15661 atttgaagga atctgtcctt ttcatcatga ttgtttggaa gggttagcat caggacctgc
    15721 gattgaaaaa cgctttggaa gaaaagccca gactatctca tttgatcatc cttattggac
    15781 gattgaggca gattatcttg ctcagtgtgt gtataacaca acgttactat atgcaccgga
    15841 agtaataatt ttaggcgggg gtgtaatgaa acagccgcaa ctactcgagt tgattcgcca
    15901 agcgtttaaa gaaaaaatgg gttcctacgt ggatacgccc actctcgaag aatacctact
    15961 aactccaatg cttgctgaca atgcgggctt gattggctgc ctagctttag caataaagaa
    16021 actcaatcat tagaatagta tttattagaa ctattcataa cataccggaa gtttaaaagg
    16081 gtattctgaa acttaaatag tctcaattca ttcttctttc ttgagaatc
//
LOCUS       DADVXB010000061        16112 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.062, whole genome shotgun sequence.
ACCESSION   DADVXB010000061 DADVXB010000000
VERSION     DADVXB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.062"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(239..1966)
                     /locus_tag="KB902_001518"
     CDS             complement(239..1966)
                     /locus_tag="KB902_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBB6808353.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(1959..3152)
                     /locus_tag="KB902_001519"
     CDS             complement(1959..3152)
                     /locus_tag="KB902_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6808354.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3339..3983)
                     /locus_tag="KB902_001520"
     CDS             complement(3339..3983)
                     /locus_tag="KB902_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6808355.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4077..4211)
                     /locus_tag="KB902_001521"
     CDS             complement(4077..4211)
                     /locus_tag="KB902_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBB6808356.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4213..6345)
                     /gene="feoB"
                     /locus_tag="KB902_001522"
     CDS             complement(4213..6345)
                     /gene="feoB"
                     /locus_tag="KB902_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBB6808357.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6342..6815)
                     /locus_tag="KB902_001523"
     CDS             complement(6342..6815)
                     /locus_tag="KB902_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBB6808358.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7216..7440
                     /gene="nrdH"
                     /locus_tag="KB902_001524"
     CDS             7216..7440
                     /gene="nrdH"
                     /locus_tag="KB902_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBB6808359.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7599..9758
                     /gene="nrdE"
                     /locus_tag="KB902_001525"
     CDS             7599..9758
                     /gene="nrdE"
                     /locus_tag="KB902_001525"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBB6808360.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9808..10773
                     /gene="nrdF"
                     /locus_tag="KB902_001526"
     CDS             9808..10773
                     /gene="nrdF"
                     /locus_tag="KB902_001526"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBB6808361.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10862..12001)
                     /locus_tag="KB902_001527"
     CDS             complement(10862..12001)
                     /locus_tag="KB902_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6808362.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12310..13023)
                     /locus_tag="KB902_001528"
     CDS             complement(12310..13023)
                     /locus_tag="KB902_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBB6808363.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13277..13978)
                     /gene="nagB"
                     /locus_tag="KB902_001529"
     CDS             complement(13277..13978)
                     /gene="nagB"
                     /locus_tag="KB902_001529"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBB6808364.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14212..15744
                     /locus_tag="KB902_001530"
     CDS             14212..15744
                     /locus_tag="KB902_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6808365.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15935..>16112)
                     /locus_tag="KB902_001531"
     CDS             complement(15935..>16112)
                     /locus_tag="KB902_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6808366.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         4986 a         3336 c         2826 g         4964 t
ORIGIN      
        1 ttgagaatgc acttcgtaca taataaactt taatcacatt agtctttcat acctacgatc
       61 gatctctttg actcgcaccc ataaattcat aatagtttgt cggcgtcttt gaacgtttcg
      121 aagatgagct acgcattctc tttttttata gacaaaaaag atagagacga acatggagct
      181 tccaaatttg gatatttgat ccaattttgg aagctccatt tatttcgtgt ctgtcttttt
      241 attttttcca gctttcgact aattcttggt tctctttgat ccagtctttt gctgcttgct
      301 gtggatcttt tccattgttg atttccaaca taactttttc catatctttt tctgaccaat
      361 ggaaattgtc taatactttg taagcttctg gctggtcttc tttcaatcct tttcgaacca
      421 tcgtatggat ctgctcttcg cttcccattc cgttttcagg atcttctaag tatttcagat
      481 catatttggc aaacatccaa tgaggtgtcc atcctgtaac tacaattggt tcgtgttttt
      541 tgatcgcttg acctagtgca acggtcattg ctcctgaaga agatgtctct actttccagt
      601 ctttcaagtt gtcatatttt tggatcgtgt tttcagcagc cgtaactaca ccagctcctg
      661 gctcgattcc tatgattttc ttacctgcct gatcggttaa ctcatcgatc gaatttacat
      721 ccatgtaggc tggcactgct aaaccaactt ttgctcctgt caaattggca cctaggtctt
      781 cgacttgatc tttatattgt gcatattgtg aaccatgagt tttaggtagc caagctgaaa
      841 ccatggcatc tgactcgcca tttgaaacag atttccacat gattgaatta tctaatggcg
      901 tcatcgttac atcatagccc atttgtttca atacttcacc gactacattt gttgaagcaa
      961 cttctgtatc ccattcaaca taagataagt tgatacgttt tgtttctttg gcagatgaaa
     1021 aactccctat accaatcgca cctaagatca ctactactac agcaccaatg atcagtcctt
     1081 gacgtttttt acttttctgt gttgttgctc ctgcagcttt tttattgttt ggctggttca
     1141 aatgctgtgt aaaacggtca atgatgattg ctaagataac taatgcaacc ccgttgacaa
     1201 atccattccc gacttgtgct ctttgcaatg ctgataatac gccgcgtcct aagccgggtg
     1261 caccgatcat agaggcaata acgaccattg aaagtgacag cattgttgtt tgattgatcc
     1321 ctgccatgat cgtactttta gctaaaggca attctagttt gaatagtttt tgacgacttg
     1381 tgctcccgaa tgaatcagaa gcttctacta attctttagg aacttgtcga atccctaaat
     1441 tcgtaaaacg aacggttggt ggcagagcaa agatgactga ggcaaatacc cctggaacca
     1501 tcccgatacc gaaaaatgca actgctggaa tcaaataaac gaatcctggc attgtctgca
     1561 taaagtcaag gatcggtttg ataatacttt gggctttact gctttttgcc atcaagatcc
     1621 ctaatggtac cccaatgatg atcgagatca cactagataa aagaacaagt gtgacagtat
     1681 tcatcaaatc attccataga ccttggttat aaataaacca tagaccgatt aatgtgaaca
     1741 acgtaagtcc tggacgtttc ttagaaataa agaaagctgc taccgtcaat aacaagataa
     1801 acaaaggagc tggaatcact aacagtaaat ttgtaatccc cgacatcact gcctgtccaa
     1861 tcgtttgtaa aaatgaaaat aggccagaaa aagttgtcgt aaaccattct gtgatatttt
     1921 ctacccagtt tgccactggt aattgatagt tcaatagatt attcatgttc actcacctcg
     1981 cttgtttctg ctaatgcttc aatcacacta cctcggatga cgacaccttt taattttcca
     2041 tcctctacaa ctgcaagtgg agtcggtgag tcataaataa tattgaaaat atcacttacc
     2101 accatgtctt tcccaatcac cgtcacattt tcatctagga agtcgatcaa tggacgtttt
     2161 tgcttcctag cttctaacgc ttgatctgca gtgatgatcc ctttcaggtg tctctttctg
     2221 tcaacagcca tcagcatgct gacttcttca ttacgcatcc ttgtcaatgc aacgtttggt
     2281 ccatcagatt cgatattcgt cgtcaatgca ggtaccatga tgttttgagc cgtaagcact
     2341 ttggaacgat cgacttcttc cacaaattca cgtacataat catttgctgg attggtcaat
     2401 atttcttcac ctgttccgat ctgcatgatt tcgccgtctt tcatcaaggc gattctgtcc
     2461 ccaatccgta aagcttcatt caaatcatgg gtaatgaaaa taatcgtttt ttgaacattg
     2521 gcttgcaggt ccagtaattc gtcttgcatt tctcgccgga tcagcggatc aagagccgag
     2581 aacgcttcgt ccatcagcaa gatctcagga tcatttgcta aagctctggc taggccaacc
     2641 cgttgttgca tcccaccaga taactgacta ggatattggt ctttaaatga aagcaaacta
     2701 gaattttcta atgctttttc tgctttttct tgtcgttctt ctttaggtac accacggact
     2761 tctaacccgt attctgtatt ttccaagatc gttcgatgtg gaaacagacc gaagttttgg
     2821 aaaaccatat tgattttatg acgacggact tctcgcaatt cttctttgct taacttcgat
     2881 acatcttctc catcaatata gatactgccc gaagttggct caatcagacg attcaataga
     2941 cggatcaatg tggatttccc actcccggaa agccccatga tcacgaagat ttctccttct
     3001 tttacgtcaa aattcacgtc atacacacca accgttgcac cggttttctt taaaatctcc
     3061 gttttcggct ggtgatcatt catcatatct aaagcggctt gtgtcttttt accaaatatc
     3121 tttgttaaat gttttacttc tacttttacc aaacaaattc tcctttttta tgtaaattca
     3181 tttttctttc tgaaaaaagt gaccacacta tgttaacatc atgtagtcac tttgtcaaaa
     3241 atgaaagaaa tttgcttgtc caaactgaaa aaaacttggc taaatctttg taaataaaag
     3301 gtttagccaa gttaatattt ttttaatatt tcacacaatc attctgcaag ctgatgctcc
     3361 gggtaaaaaa agtttgtcat acgctgtagt gtatattcat ttccaataaa atgaacgatg
     3421 tcccctgccg taaatttagc ataggggcca ggtgaaacaa gcagttcttc attatgagaa
     3481 attgcgataa ctgtggcgcc agtcgcctgc cagatattca actcgctaat tgaacggtcc
     3541 agatgcattg ctttttctga taaagataat tcaaacggaa gtaaaggatt catcttatgt
     3601 attcgcttcg tttgattgac cagctgatcc aataattgag aaaaatgatt cagctcatct
     3661 tgttgcttct ccacacttgc catgatttct gcttttgtat cttggatgga ttgtacatct
     3721 tgatattgca ataggaaatc ttttgctttt tccttcgaag caacaaatgc cccacttcca
     3781 tgccgtactt ccatgattcc aagatctacc agcacattga tagccttgcg ggtagtctca
     3841 ggagaagcat tgtacgtact ggcaagtgtt gagcgggcat ggatcttctc acccacttta
     3901 tatcggtttt caacgatacg ttcggctaaa tcaacagcaa tctgctggta gcgcgggcgg
     3961 acgatttttt tctttccaga cattttcttt cctctttctt tttttacttt ccctcatctt
     4021 actatgctct agcaaaataa gcaaaaaagg ggagaatagc ctcttgcaac gactgatcat
     4081 cgcttgatct gttccttttt tactgggcaa gctgtttgac agtcatcaca attcttaccg
     4141 gattttaaac gagtatagac aattgcgcct gcacttccaa agattaacac acttaataag
     4201 aatgtcgcca tcctattcct ctccttctaa tgacaatata gtataaaact ggttcttgga
     4261 ttttggctga cggaacaaaa cataaacgag tcctatcatc agtaaaatag caagatacgt
     4321 ccctaacgct acctgtccac cctccaataa gtgtcccaac tgataaatca caaaactaac
     4381 taaataagct aaaccgcatt gatagcctat ggcgatccaa gtccatttct tggcattcat
     4441 ttcccgatgg atagccccaa ttgccgcaaa acaaggcgca caaagtaaat tgaaggctaa
     4501 caatgaataa gctgctgcgg gagtatatgt gtgttgtagc acttgccaga tttctctgcc
     4561 attttcggat acttccgcat gaccaaacaa aataccaaat gtgccaataa tattttcttt
     4621 agcgaccaat cctgtaatcg ctgcgactgt tccttgccag tttccccaac caagcggctg
     4681 aaaaacaact gccaggattc gcccgaaaaa ggctaagata ctttggtctt cagaaacagg
     4741 ttgagcataa aaattataag aagagctgaa ccagatcacg atactagaaa caaagataat
     4801 cgttcctgct tttttaacaa aagacttgct gcggtcatag gtttgtctta ggaccgctga
     4861 ccattgagga aaatgatatg cgggcaattc catgataaaa ggagctgtat ctccagcaaa
     4921 caaacgtgtt tttttcaagc tgattccaga gaaaataatt gcagtcatac caagaaaata
     4981 ggcagaagga gctacccaag attgatgagg aaaaaaggcc cctgctacta aggcaataat
     5041 cggcaacttt gcagaacaag gcatgaaggt tgtgaccatg atcgtcaaac gacgatcttg
     5101 ctcgttttca atcgtgcgac tggccatgac gcctggcact ccacatcctg tagcaatcag
     5161 cataggaatg aaggattttc ctgaaagacc gaatttcctg aaaagtcgat ccatgacaaa
     5221 agcgatcctc gccatatatc cgcagtcttc cagaaagctc aagcataaaa acaatataat
     5281 caattgcggt agaaatccta acactgctcc cacgcctgcg atgatgccgt tcaagatcag
     5341 ctcctgcatc catcccgcta cttgccattc agctaacaat ctgccaacat gttctggtaa
     5401 ccatgtacca aacaatgtgt cattgatcca atctgtcccc attgttccta ctgtttgaat
     5461 agccagataa tagatcagcc acatcacaaa tgcgaagatc ggcaaggcta accaacgatt
     5521 cgttgcaatc tgatcgattt tgtcactcat cgataattgg aaagaatcat ttgacacaac
     5581 acagagtgta catagttggg taataaattc ataacgttca ttgaccagaa tcgtctcact
     5641 atcgtcgtcc aatagtttct ctgttaactg gatcagttgc tcgatctctt tttgctgaga
     5701 aactgctatc tcgtaatcct ctcttacctt ctgatctcgt tcaaaatatt tcattgcata
     5761 ccagcgtttc ttgccgcttt gttctcctag tacatcttca atttcatgta aagctgcttc
     5821 taaacgtgga tcatatgtac agggaacagg aatagaaggc cgcttttttg cagactcctg
     5881 aatcttttcg attagttttt cgattccttg ctttttcaat acgctgattg gtaaaactgg
     5941 tacaccaaga ccataggaaa gcttttctag attgattttt tttccttctt ttttgatgac
     6001 atccatcata ttcagaccaa tgatcatagg aatgtctaaa tccaataact gcgtagttaa
     6061 ataaagattt cgttctaaat tggtagcatc aataatgttg atgatcagtt caggctgttc
     6121 ctgaaccaaa taatctcttg caatcacttc ttctggtgta taaggagaca aagaatagat
     6181 gccgggtagg tcctgaatat gaatgttcgg attttttttc aacgatcctt cttttttttc
     6241 tactgttacg cccggccaat tccctacata ttgattcgaa ccagtcaaga gattgaacaa
     6301 gctagttttc ccgctgtttg gatttccgac taacgcgata ttcattcttt ttcctccctt
     6361 tgtatcaaga ttagttcggc ctctgacttt cgtaacgtca gttcataccc tcgcactgtc
     6421 agttcgattg gatctcccag aggggctagt tttcggataa ctatttttac atttcgcgtc
     6481 aatcccatat ccattaaccg tcgcttcact gcgccttgtc cgtggattgc tacgacgatc
     6541 ccagtctctc ctgcttttaa ttgatcaaga gaagtccagc tttcagagga agcagtcttt
     6601 ttattgacaa agatttgacc tagtatttcc cgacttactg ccactcgatg actttttacc
     6661 agtaaaatgg cattgttgcc tgataaattg acgacgacga ttttacttcc ggcaacgatc
     6721 ccgatatttt gcaaatggcg ttttgttttt tcttctgttt cgattcgttc gacttgataa
     6781 acgaaattct gctttgcctg cgctaaggtc tgcatattga ttcctctctt gtgaaataaa
     6841 tcatgtatta aaatcattca ttatatgttc taattttctt acgtgttacg caaataaatg
     6901 agaatcattc tcacatagaa tactctcggt aattgagaat gtcaattata cttgtgatat
     6961 tatgagcgaa tctttagtat tgatagataa aaatgagaaa aaaatatttc ttcatagttt
     7021 tccacaattt tttctctatt aaatttgcta ttttcccaca cgatacttgt tttcagctct
     7081 tttttcaaaa acacaaaact tagtattcca cagtttccac aacacaatat gtagtgtttg
     7141 ttgtttgact tttttactaa gagttttata ctatctatta tagataataa gaatgtgtta
     7201 gaggaggcac tcaccatgaa cgtaaaaatc ttttctaaaa ataattgtat gcaatgtaag
     7261 atggtcaaac ggtttttaac agaaaatcaa attgcttttg aagaagtcaa tatcgatgaa
     7321 cagcctgaag cagtagactg gttgaaagca caaggattcc aaagtgttcc tgtcattact
     7381 tctgatgcag aaacagttat cggattccgt cctgatcagt tgcgtaaact tgccagctaa
     7441 catgactaaa agaatcaaaa cgtgatacat ggatttgaag ggcttgagac agcaccagtt
     7501 tttgtcgcaa acttccaaat ccttttttaa agcttaaaaa caatgcaatg atttgcaatc
     7561 aagcatcatc aaatacgaaa tgaaggttgg gcgtacgtat gagtcttaaa aatttacaag
     7621 atgtcagtta tttcaagctg aataatgaaa tcaatcggcc agtcaatggt caaatccctt
     7681 tgaataagga taaagaagct ttagttgcct tttttgagga aaatgtcaaa ccaaatacga
     7741 tgacttttcc atctattatg gaaaaaatca attacttgat cgatcaagaa tatatagaag
     7801 cagaattcat tcaattgtat tcaccatcat ttattgaaaa gctatatcaa tttttggacg
     7861 agcaacattt ttctttcaaa tcttttatgg ctgcttacaa attttattct caatatgcgt
     7921 tgaaaaccaa cgacggttcc gcttatctgg aaacttatga agatcgagta gccttcaatg
     7981 cgctttactt tgcgaacggg gatgaagaat tagcacttgc tcttgcagac gaaatgatcc
     8041 atcaacgata tcagccagct acaccttctt tcttgaatgc tggacgtaaa cgtcggggcg
     8101 aattggtgtc ttgtttcttg actcaagtca ctgacgatat gaactctatc gggcgctcaa
     8161 tcaactctgc tttgcaattg tcccgtattg gtggcggcgt agggattact ttatcaaatc
     8221 ttcgtgaagc cggcgctcct atcaaaggat atgagggtgc tgcaagtggt gtcgttccag
     8281 tcatgaaatt attcgaagat agtttcagct attctaatca attaggtcag cgtcaaggag
     8341 ctggcgtggt ttatttgaac gttttccatc cagacattat tgctttcctt tcagcaaaaa
     8401 aagaaaatgc agatgaaaag attcgcgtaa aaactctttc tcttggcgtg atcgtacctg
     8461 ataaatttta tgaattgaca cgtaaaaacg aagatatgta tttatttagt ccatatagtg
     8521 tcgaaaaaga atatggtgtc ccattctctt atgtaaatat tacagctgag tatgatcatc
     8581 tagttgcaaa tccaaacatt cgcaaacaaa aaatcaaagc gcgtgatctt gaaaatgaaa
     8641 tctcaaaatt acaacaagaa tctggctatc cttacgtaat caatattgat acagcgaacc
     8701 gcgagaatcc aatcgatggc aagatcatca tgagtaattt atgttcagag attttacaag
     8761 ttcaaacgcc ttctgtgatt aacggcaaac aggaatatga agtattagga acagatatct
     8821 catgtaactt aggctcgaca aatatcgtga atttgatgca aagccctaac tttggtcaat
     8881 ctgtgcgtac gatgactcgt gcattgacat ttattacaga tgcatctgat atcgatgtcg
     8941 taccaccgat ccaaaacgga aataagctga atcatacgat tggattaggt gccatgggct
     9001 tacacactta tcttgcaaaa gaacaaatgg aatatggctc agaggattca ttagacttta
     9061 caaatattta cttcatgctg ttgaattatt ggacacttgt tgaaagcaac aatatcgctc
     9121 gtgaaagaaa acaagttttc cataattttg aaaaatcagc ttatgctgac ggcacttatt
     9181 tcgaaaaata cgtaactgga gaattccagc caaaatcaga aaaagtcaaa gcattgtttg
     9241 aaggcatttt tatcccaact gctgaagatt ggaatgcttt gaaacaagca gtaatgaaag
     9301 atggactgta tcatcaaaat cgcttggcag tagcaccaaa tggctcaatt tcatatatca
     9361 acgatacgag tgcaagtatt catcctatca ctcgcatgat cgaagaacgc caagagaaga
     9421 aaatcggtaa aatttattac ccagcgcctt atctatccaa tgagacgatt ccgtattaca
     9481 cttctgctta tgatatggac atgcgtaaag taatcgatgt ttatgcaacg gcacaacaac
     9541 acgtcgatca aggcatgagt ttgactttat tcatgcgttc tgaaatccca gaaggcattt
     9601 atgaatggaa gacaacaacg aagcaaacga cacgtgattt gaatatttta agacattacg
     9661 ctttccacaa aggaatcaaa tccatttatt acgtacgtac ctttactgat gatgcagaag
     9721 aaatcggaag caatcaatgt gaaagctgcg tgatctaata tcatagatag attcgcttat
     9781 tcatatttta attaaaggag cattctcatg tcagaaacat attatgaagc aataaactgg
     9841 aatgaaattg aagatatcat tgataaatcc acttgggaga agctgacaga gcaattttgg
     9901 ctagatacac gtatcccact ttcaaatgac ctagatgatt ggcgtacatt gtctcaattg
     9961 gaaaaagata cagtaggaca tgtatttggc ggtttgacac tgctagatac tgtccaatct
    10021 gaaagtggca tggatcagtt gcgtaaagat gtccgcactc cccatgaaga agccgttttg
    10081 aacaatattc aattcatgga atccgttcat gccaaaagtt attcttctat ttttagtaca
    10141 ctgaatacga aaaaagaaat cgaagaaatt tttgactgga caaatacgaa tccttatctg
    10201 caaaaaaaag ctgagcgtat caatgaaatc tacaaacacg gtacaccgct agaaaagaaa
    10261 attgccagcg tctttttaga aacattcttg ttctattcag gtttttatac tcctctttat
    10321 tatttaggaa acaacaaatt ggctaacgta gcagagatca tcaaactaat catccgagat
    10381 gaatctgtac atggaaccta catcggttac aaattccaat taggattcaa cgagttacct
    10441 gaagcagaac aagaaacgtt aaaagactgg atgtacaatc ttctttatga gctttacgaa
    10501 aacgaagaac gttatacaga agaattatac gatccaatcg gctggacaga agaagtcaag
    10561 acattcctac gctataatgc caacaaagca ttgatgaacc tagggatgga tccactcttt
    10621 ccagatactg ccaatgatgt caacccaatc gtaatgaacg ggatttcaac aggcacaagc
    10681 aaccatgact tcttctcaca agtcggaaac ggctatttgt taggtcatgt agaagcgatg
    10741 aaagacgacg attatttgat tggattggaa taaggattta ttttaattca aaaatttttc
    10801 gaaaaataaa aagagtttag cgtacagata ttttaaatgt acactgaact cttttttatg
    10861 cttattcact tgtttcttcc agcacttttg gactgtctaa cttttccgaa acatgttcca
    10921 ttcttctcaa taaatagatt ttccggatat ttaatattat cgtcttaatc actgcataga
    10981 caggtatgca aatcagcatg cctaatattc ctgcgacact tcctgctcca atcaatacca
    11041 agatgatcgt caaaggatgg atattcattg atttcccaaa taacaacggc ttgatcaaat
    11101 ttccatctaa ttgttggatc actaaaatcg acaacgccat atacaaagct tgaaatggag
    11161 agataaacaa accgacaatg attgctggta ccgctccaat aaaagggccg acatacggga
    11221 taatattcgt gattccgcaa atgaccgcaa gcaacaagct ataaggctga tcgaatattc
    11281 tcattgccaa aaagctcatt acaccaataa tcaaagcatc taagatcgta ctgctgatat
    11341 aggcagataa tgtttcgttt aattctttta ccgtttggcg taactcttta cgaatcgctt
    11401 tcggaaagaa gtgagacaac gcatcaataa atttgtgccc atccttgaac ataaatagca
    11461 aaataaatgg aacggtaaat aacaaaataa aaaattgcat cataaatgaa atgatttttg
    11521 agacacttgc agataaactg actaatatga tattgaacaa attactaaga gataaatttg
    11581 ctgatgctaa ttgttcttcc aaattgaaat ttttaaactc ttcccgctgc gccaattcat
    11641 ttaaccattt gcttgtttca tctgcataca ttggcaagct ctgggtcaat tgaattgtct
    11701 gttccattaa ctgaggcact acattcatga cagttaaaac aactaaaatg attacgacca
    11761 aaaacgtcaa taaaaaaccg aacactctcg ggatccgatg cttttcgaga aaaacaacga
    11821 ttggatcgaa catataatag ataaaaccag caacaagcaa tggtaaaaaa attgccgaaa
    11881 gcattttcaa tattggacta aaaatattcg gcatttgtaa aataaagtac acgccgatga
    11941 tcgtgagtac tagctccact gtccagaaaa ataattttga ttgtttaaaa cgtgattgca
    12001 tacatctcct ccaaggtcct ttgatacttc tattctatca tttaacaaag agttacgcgc
    12061 tgagattttc atttgcttaa aaaaaacaaa aaaaataaac atattttaat gagtagacga
    12121 gtacttaaac aaaaacacgg tttggagtag tgacaaaaat tatactgcag tccctttttc
    12181 caaataaacg gtgttcaaaa gcttgcatct tcgtaataag cccagccaaa cgaaaaatat
    12241 aaggaactat ttttatttgg ctgggcttat tacttgatgt aggacatcta ttttacaacc
    12301 tcagatcatt tattgcgcaa tactgactaa atgcaacttt gtgatatttt tgtgtacgga
    12361 caactcctcg atcacatcgg cataagtgag cccttttgga agatcaatcg tatagatatt
    12421 tttgtacact cggtagtcat caacgaattt tacgtcaaaa ttcacatctt cgattacgat
    12481 atttttctct tcaaaataat cggtaagaaa atctttggtt tcttttctat ggataaattg
    12541 gatttctaac tttttagtcg taggtacatg gatcacgcgt ttcactactg tgagtgcaat
    12601 agcaatcccg ataaaactga tgatcgcaat ggaatagtaa cccatgccga tggcgatccc
    12661 taatccagca attgcccata aagaagcggc agtcgtaagt cccgtcaccg attgtttcgt
    12721 gacgatgatc gttcccgcgc ctaagaaacc gacaccactc accacttgag caatcagcct
    12781 tgcttcatct gaacgaatcg ttccagcaag ctgtggatac tctaaagcat ctcttaatgc
    12841 accactagcg atctcaactt ggatcaatgc aatgatacat gctcccatac aaactaaaat
    12901 atgcgtacgc atacctgctg gacgattttt atattgtcgt tcaaaaccga ttgctccgcc
    12961 aaatagcata gcgatcccta aacgtaaaat aatctctgga attgtcaata ccatatcatt
    13021 catctaaaca ccctccagtc caatatatca tgtctgaaag gagcagacaa aaaaagtgca
    13081 atttttacct cttacgaaaa aaggactgtg acaaaatttt tgtcatagtc ctttttatga
    13141 ataaacggtg ttcaatcagc tgaccctcgg tattactcaa caaacggcaa aatatgggga
    13201 gctatttttc ctttgtcttc tctaatactc aggtcaaaac gctgatttca caacctcttt
    13261 agcctactat tgaaaattac aacttacttg ctgcttcttc atcgatgatc acaacaacat
    13321 tgtcgtgatt ttgcaataca cttgctggca aatgattcgt tacaggtcct tcaatcatcc
    13381 ctttgattgc atcagctttg ctttcgccaa atgccatcaa gacgatttct ttacttttca
    13441 taattgaacc gattcccatt gaaacagctt ttgttggtac atcttctgct ttatcgaaga
    13501 atcgtttgtt tgcattgatt gttgattctg ttaagtcaac tactgaagtc gttccgtcaa
    13561 atgaagcacc aggttcattg aaaccgatat gtccattttg cccgattcct aagatttgga
    13621 tatcgattgg atgtgcatcg atgatttgat catacttttt gcatgctgct tccagatctt
    13681 ctgcttttcc atctggtaca aacgtttctt tgaatggttt tttatcaaat aattggacat
    13741 ccatgaaatg acggtagctt tgttcatctg aaccgcctag tccaacgtac tcatctaagt
    13801 ttacagaagt catttcactg aaatccaaat cgcttgaagt catttcttta tataaagtaa
    13861 ctggtgtgct tcctgttgcc aatcctaata cttttgcacc tttgttcata ccttctttga
    13921 tgatttcaaa tgcttttttt ccgccttctt cagcgttttt tacacgaatg atttccatag
    13981 tgattgctcc tttatatttt ggtatagccc aattatagca ttcttttttt ctttttacaa
    14041 taattagtat agaccaaatt gcattttttt cattttcttg acaataaata ggaatccgtg
    14101 ttaggtttca taagatggtt caatcaaaca atccatgttg catgaaaacc aagcaagtga
    14161 ttcactgtgg acgctttatg tctgcagttt ttttatgaaa aaggagttat tatgagtata
    14221 ctgacattaa acaacattac ccagcaattt ggcgacaaaa tcctctatga aggtgtcgat
    14281 ctgcaattaa atgctggcga acatcttggg ctgattggac aaaacggagc cggtaaaagt
    14341 acattgatta aaatcatcac tggtgagatc ttaccagatg acggacagat ccattggcaa
    14401 aaaaatattc acaaaggtta cctcgatcaa tatgtggaag tcgatgaaac attaacaatc
    14461 gaagaatttc taaaaactgc gtacgcaaaa gaatacgaaa aggaagaaaa aattgctttt
    14521 ctttaccaaa catatagcga gaccttcgat gattccttgc tggaaaaagc tgggaaactc
    14581 caaacggaat tagaccaagg agtgttttat caaatcgaca ccttagttgc tgagatgagc
    14641 agcgggttgg ggatcgatgt cttaggttta gattcactgt tgaaaaatct aagtggtgga
    14701 caacgttcaa aggtgatttt agcaaaacta cttttagaaa acccagatgt tctgatctta
    14761 gatgaaccaa ccaatcactt agatgatcag catatccaat ggctgacgca gtttcttcag
    14821 gattttgacg gtgcgtatat cgtgatttcc catgaccaag aatttcttga tcagatcacc
    14881 acccatatcg cagacatcga gtttggaaag attactaagt atactggcca tctaaaacaa
    14941 gcattgaaac aaaaggaaca aaatcgcgaa agctatttgc gccaatatca tgctcaacaa
    15001 aaacaaatcg aaaagaccga agcttatatt cgaaaataca aagccggttc ccgatcaacg
    15061 atggcaaaaa gccgacaaaa acaattagat aaaatcgaac ggctgacgcc tccagcttca
    15121 gcaagtaaag ctgtctttga ttttccattc tcgcctattg tcacgacatt agcagtggaa
    15181 acaactgatt tagtcatcgg atatgatcga ccgctacttg cacccatcaa tttgaccatc
    15241 cgctttggtg aaaatattgc cattcgaggc ttcaacggga ttggaaaatc tactttatta
    15301 aaaacactga tcggtgagat tgaaaaaata agtggcgatt tccacttccc agataacaca
    15361 aaaatcaatt acttttcaca agatctgtac tgggaaaatc cattagaaac accactacaa
    15421 tatttaagca gtcaatttcc aaaagcgact atcaaagaat tacgtcgcca actagctaaa
    15481 gcagggttag ttaatcaatt agcaagtgaa cctctcacta cattaagtgg tggggaacaa
    15541 actaaggtga aacttgcaca gttgacaatg aaccaaggta atttactgat tctcgatgaa
    15601 ccgacgaacc atatcgatca agaaacgaaa gaaagcttac aagacgggat acagaaattt
    15661 ccaggaacag taatcatcgt ctctcatgaa caagaatttt atcaagatct tgtgcaacga
    15721 gtcattgaga ttgaaccaaa ataaacgttt gattgaatag ttgaaaaaaa ggagctgtga
    15781 caaaagtttt gtcacaactc cttcttctga ataaatggtg gccaattagc tgaccttcgg
    15841 tattagctca aaaaacggca aaatatgagg agctattttt atttggctat tcttattact
    15901 tgatgcagaa cagcttttca caacctcttt tcgtctattt tttattttcg agatttctct
    15961 ttcctttaaa aacaactgtt tgaaagaaga acgcacatcc ttgaaaaaca agcccgctaa
    16021 ccgttacacc taaccagcca tactgctgcc acattgtcgt ccctagcaat gaaccagccg
    16081 cacctccaat aaagtacata aacataaata ca
//
LOCUS       DADVXB010000062        15884 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.063, whole genome shotgun sequence.
ACCESSION   DADVXB010000062 DADVXB010000000
VERSION     DADVXB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.063"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(343..543)
                     /locus_tag="KB902_001532"
     CDS             complement(343..543)
                     /locus_tag="KB902_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6808367.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(848..2080)
                     /locus_tag="KB902_001533"
     CDS             complement(848..2080)
                     /locus_tag="KB902_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBB6808368.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            2335..2904
                     /locus_tag="KB902_001534"
     CDS             2335..2904
                     /locus_tag="KB902_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6808369.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(3082..3522)
                     /locus_tag="KB902_001535"
     CDS             complement(3082..3522)
                     /locus_tag="KB902_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBB6808370.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3680..4444
                     /gene="map"
                     /locus_tag="KB902_001536"
     CDS             3680..4444
                     /gene="map"
                     /locus_tag="KB902_001536"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBB6808371.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4476..5399
                     /locus_tag="KB902_001537"
     CDS             4476..5399
                     /locus_tag="KB902_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBB6808372.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5475..6614
                     /locus_tag="KB902_001538"
     CDS             5475..6614
                     /locus_tag="KB902_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBB6808373.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6607..7407
                     /locus_tag="KB902_001539"
     CDS             6607..7407
                     /locus_tag="KB902_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6808374.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7407..8234
                     /locus_tag="KB902_001540"
     CDS             7407..8234
                     /locus_tag="KB902_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6808375.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8212..8946
                     /locus_tag="KB902_001541"
     CDS             8212..8946
                     /locus_tag="KB902_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6808376.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            9046..9912
                     /gene="rfbA"
                     /locus_tag="KB902_001542"
     CDS             9046..9912
                     /gene="rfbA"
                     /locus_tag="KB902_001542"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBB6808377.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9926..10498
                     /gene="rfbC"
                     /locus_tag="KB902_001543"
     CDS             9926..10498
                     /gene="rfbC"
                     /locus_tag="KB902_001543"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBB6808378.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10520..11548
                     /gene="rfbB"
                     /locus_tag="KB902_001544"
     CDS             10520..11548
                     /gene="rfbB"
                     /locus_tag="KB902_001544"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBB6808379.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11646..12497
                     /gene="rfbD"
                     /locus_tag="KB902_001545"
     CDS             11646..12497
                     /gene="rfbD"
                     /locus_tag="KB902_001545"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBB6808380.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12531..14564
                     /locus_tag="KB902_001546"
     CDS             12531..14564
                     /locus_tag="KB902_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808381.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14608..15873
                     /locus_tag="KB902_001547"
     CDS             14608..15873
                     /locus_tag="KB902_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBB6808382.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNHNSYNSILNIYGLIGFGIAALLLILFIGRLTLKAD
                     LSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEEFYVME
                     EAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4882 a         2738 c         3286 g         4978 t
ORIGIN      
        1 aaacttctga attccatact ttataaaaat ctttgataaa tctattcgaa gggtcaaatt
       61 taaaccataa ttgtgttttt ccttccatca gcataaaagt tcacctcaaa aagagtatac
      121 gaacgaatgt tctttttgtg aaggcggaat ttaatatact gaataataga aaacaagtac
      181 ttgtgccaaa ttatgtgcca aaaaaattcg aattcaacaa aatgtaaaca aatagaaaac
      241 cttctatatt aagatttcct gcaataacaa acacaacaga agacgtgtaa tagttagtca
      301 ggaacgtaca aataacccct gtatcctttg cggtacaggg ggttattttg tataagtaga
      361 cattgtagtt tctaaactgc tatgtcctaa acgtttcgat acgctaagta tatttactcc
      421 ttgataaagt aaaatagatg catgcgtatg tcttagtcca tcaataaaca gtcgaagaga
      481 aaatagggaa aaattgatta ctaaagaaaa acttactagg tcgacggtgt agttgatttt
      541 catacttcaa tagattcgaa ttaaacgatt tcgattggct tataccagtc ctatccaacg
      601 aaagatatat cgttcttaac tctagcggta taacttgaag ctttacgtaa agccaatggg
      661 aatgaactgg agatgacttt ttattatttt tagtaatagc tgatgggtta atacttacaa
      721 ctttcctttt caaagtacca tataaaaaaa cggtggggtt gtttagcgaa ataaaggatc
      781 taagccaata gcttagatcc tttattctat gctttatatt attttttgca tgtgtgcgaa
      841 agtatactca agcccaatcg ccatttcgga aaatcggtac tgtagagcca tcttcacgga
      901 ttccgtcgat atccatcttg tcagatccta ccatgaaatc tacgtgggtt tgacttctat
      961 tcaatccagc ttctgctaat tcttcatcgg acatttctgt accgcctttc acactgaagg
     1021 cataagcaga acctagtgct aagtgattcg atgcgttttc atcaaataat gtattgaaaa
     1081 agatgatgcc agattgagaa ataggtgaag ggtcaggtac aagtgcgact tctcctaaac
     1141 gacgcgcacc ttcatctgta tcaagcagtt ttgctaagac atcttctcct tgttcggcag
     1201 aaaaatcaac aacttttcca tctttaaaag taaatttcat acccgagatg atggtgccag
     1261 cataactcag tggctttgta cttgaaatgt aaccatctac tcgatgactg tcaggtgctg
     1321 tgaacacttc ttccgtcggc atatttgcca tgaatttttc tccacgagca ttatagcttc
     1381 cagcgccttc ccaaagatgg tttttaggca atccgataat gatatctgta ccgggagcag
     1441 tatagtgaag ggcagaaaat tgttctcgat tcaattcttc tgcttttttt gctaattttt
     1501 catcatgctt cttccatgct aagacagggt cttcttcata gacacgagtc gttttgaaaa
     1561 tctgatccca taatgcctca acttgttttt cttctggcag ttctgggaag acttttgctg
     1621 cccattgttt accagccgca gccacgacag tccaactgac tttatttgct tgagttgcct
     1681 tgcgtaaatt cattagtgct ttgccattcg ctgattgata agacgctact cgatggctat
     1741 ctacaccagc aaatgcatcg ggatcggcag aaacaacgct gatcctgctt gctccttttt
     1801 caagccattc atccgcttga tcgattttag attgtggtac attctcaata cgatccgttg
     1861 cagcatgtaa aagaaattct ctttggatct ggtcgtcagt ccattgaacg ataacctcag
     1921 cggctcctag tttataagct tcttgtgtga tcaatcgagc aaggggtgcc tgttccacgc
     1981 tgatctgtaa aacaactgtg tgtccttttt ctgtggctac gccagtttct gcaattaagc
     2041 gtgcatattt ttttagaagt tcattaaaat cagataacat aataaaaatt cctcctcacc
     2101 attttttctg gtaactatta gcatgatacc atttaattat gattcaaaca atgaggcttt
     2161 aaataaaaaa aggaggttat ttttttaagg ttaagtttca tgatatatgt tactacttgc
     2221 tatttcagct tgtgaagaaa atcaaaaact aattttgcat atcaaaaaaa acatgttaca
     2281 atgaaattaa tcaatggtgg aagcgttata aaaaaattaa ggagattaaa aaatatggca
     2341 agaaaaaaga cgattactag agaacagatt ttggcagctg cttatgaagt agctgccacc
     2401 gatggattta cacgatttac tgcgagaaac atcgcgaaca aaatgaattg ttccacgcaa
     2461 ccgatttatc ttgagtttaa aaatatggat gacttgagac aagctctttt tgagcagatc
     2521 tatgatcatt tacaatatga agtgttcact gttgagcata cagggaatac gattatcgat
     2581 cttgctttta attatatcca ttttgcaaga agagagaaga agttgtatcg ttcactgtac
     2641 ttagaagaat atggtggagg aaaagagatg cagaatttct cttatactta ctttgtgaat
     2701 acagtgaaac gcgatccagc ttatgtgaat ctttcagaag agcagatcga atctttgtat
     2761 aatgggacat ggatcatagc tactgggatc gcagctttga tgtcttcaag catcatccat
     2821 ccaactgatg aacagattga aaagatgatc caagacagta tagatgctat cttgaaattc
     2881 aaagaaccaa tcgaaatcga ttgaatatac tcaaaagttc cacaaatcag taggtaacaa
     2941 gagatgtgtc aaaataagga aaagttcgtt tttcttacag cgtatgcatt tttaactccc
     3001 gaagaactct tccatgaatg caatgaataa aagagccata cagattgaat aaatctggat
     3061 ggctctttta ttgcaagtat attaaatttt tgcgactagt tctttagcga aagcttctaa
     3121 attttcgata tcttcttctt cagcattcag atccacttta acattttcgg ctccttttga
     3181 tgcgcctgtt tttgcaaaag cagcatcgaa atcatccacc gatttgcaga attcatcgta
     3241 aaaagtatca ccagatccgc agacaccgta aatttttccc aatagatcca attcttgcaa
     3301 gtcttcataa aagtctacga tctcatcagg cagatcgcca tcatcgtatg tataagtagc
     3361 tactacgcaa atatctgcct cctcgaattc atctgcatct acttgggtac attcgttgat
     3421 ttcgacttcg atatccagat tttcaaatgc ttctgcaaca atatcggcga tttcttcagt
     3481 gtttcctgtc atgctagcat atacgatttt tgctaaagcc atgatgtgcc tcctcgttta
     3541 taattattta acaattatga attataccaa aacatcattg aaaagaaaat aaaacctaga
     3601 gacacctggg gaatgtcatt tggctaaatg tatgccgcta tgttaaaatg agagggattt
     3661 gtaaaaagga gacgaaaata tgattacttt aaaatcagca cgtgaaattg aaatgatggc
     3721 agaatctgga gctttattag cagatgtaca taaaaatctg cgtgatttta taaaaccagg
     3781 aatcacaagt tgggatattg aggtatttgt cagaaactat atcgagagtc atggcggaat
     3841 tgctgcgcaa attggctttg aagggtatga atatgcgact tgtatcagta taaatgatga
     3901 aatttgtcat ggattccctc gtaaaaagcc tttgaaaaac ggtgatttgg taaaagtcga
     3961 tatgtgtatc gatttgaaag gcggcatttc tgattcttgt tgggcctatg tagttggaga
     4021 atctacacct gagatcgacc gattgatgga agtaacgaag aaagctttgt acatcggtat
     4081 tgagcaagca caagtaggga atcggattgg tgacatcggt catgctatcc aaacttatgt
     4141 agaaggcgaa aatctagcga tcgttcgtga ttttattggt catggcgttg gtcctacgat
     4201 tcatgaagaa ccagcagttc ctcattacgg agaagctgga aaagggttgc ggttgaaaga
     4261 aggcatggtt atcacgatcg aacctatggt taataccgga acttggaaaa tgaaaatgga
     4321 tcctaacggc tggactgcgt atacaagaga cggcggactt tcttgccaat atgaacatac
     4381 attggctatt actaaagatg gtccaagaat tttgacatca caaggagaag aaggcactta
     4441 ttgatctatc cagtcaatag gtacgggaga ggtacatgaa agtttggaac aaaataaaac
     4501 aaaatgaaaa tctgatgcgc tttattgaga cgactcaaaa gcgcatcact gattcagaaa
     4561 tgagtacgac ctctgtcgtc gttgcttatt atttactctt gtctttattt ccattgatta
     4621 ttgcttttgg taatatttta ccgtttctcc acatcgatca agagactgta ctgacctatt
     4681 tacgagaagt gattcctgag accgtttacc agtttatcgg tcctgcaatc aaagaccttt
     4741 tgacacaaag ttcaggaggc ttgttatccg tttctgcatt agcggcttta tggtctgcaa
     4801 gtcaaagtat caatgctttg caaattgcga tgaataaagc gtatggcgta gaaaatagaa
     4861 aaaatttttt gatcgtccgt ttcttctcac taattgtcat tgtcttgttc atgattgcta
     4921 ttagtggggt aactatcgtt cttgggttgg gacagctgat tttggatgct attcagccaa
     4981 tcgtacaaat acccgtgaac tttatcgatc agttccaaac tttgaagtgg ccaatcacat
     5041 tggtagcttt atttgtcatc atgttcttga tttatttaat tgtccctaat gctcagttga
     5101 agttgaagac gatcattccg ggcacgatct tcgctactgt cggctggatg ctgttatcac
     5161 aagtgtttag tatctatgct aggtattttg caacgaggat cagcggttat cagatcatag
     5221 gaagttttat tgtactcatg ctttggctta attttgctgc tacgatcatc attttgggcg
     5281 gaatcatcaa tgcagttgtt caagaatacg tgacgggtca tcaaatcaaa aaacgtcgag
     5341 atccaagccg aaaatggttc aataaattga aaactaaatt ttctcataaa aaaaagtaga
     5401 aacaagagtt cttattgtaa atttatatca gtaatttata ataattatga ctcttaatta
     5461 aagtaggtgc ccatatgctt gtttctttta gtatggttat aagatttttt ctgacaattt
     5521 tattatcact gatattaaca cctgtattca aaatcatttc agtacaaaca ggtatggtcg
     5581 acaaaccaaa tgaaagaaga ataaataaag ttccaatgcc ttcagcgggc ggactgccta
     5641 tctttatttc atttgttata tcgactttat tcttattccg taaaattatc cctcaatcgt
     5701 atattgtacc gatcttgatt gcttctttag taatcatagt cacaggagtg ctcgatgata
     5761 aatatgagct gacacctaaa caaaaaagta tagggatctt gattgcttct cttattattt
     5821 attttgtagc agatatacgt attgattcct tcacgcttcc ttttattgga tatatccaac
     5881 taggctggct tagttttccc gtaacgattt tttggatctt cggtatcacg aatgcggtca
     5941 atctgattga cggtttggat gggctggcgg cagggatttc attgatcggt ttaattacga
     6001 taggaatcat tggatatttt ttcctccatg cttctacagt gtatattcca gttgttattt
     6061 tctgtcttgt agcaagtatt atcggttttt ttccttacaa tttttatccg gcaaagattt
     6121 atttaggcga tacaggagct ctattcctag ggtttatgat ggccgtcctt tcactacaag
     6181 ggctgaagaa cgtgactttt gtttcatcga tttctttgct gatcgtcatg ggagtgccgg
     6241 taacagacac gttttttgct atcattagga gaaaagcaaa ccgtgtttct ttttctacag
     6301 cagataaaaa acatcttcat caccgactaa tcagtttagg ctttactcat aaaggtgctg
     6361 tcctgacgat ttatgcgatg gctttgatgt tttctttcac agctatggtc atgaattata
     6421 ctggaagaat cggaacgatc atattgatta ttgccatgtt gtttgctgca attttattat
     6481 ttgaattgat tggtctgatc aatgagaaac atcagtttat tttaaaaaca ttgcgatttt
     6541 tagggaataa agagtaccgt acgcaagtaa aacagaaata tttgaagaaa tggaaccgtc
     6601 atatagatga ataacaaatt aaaccagccg atccttatta gtattgtgac ggcaaacagt
     6661 gataaaattt ttcggacact agataatttt atttcaactg taaaagatga aacagcagta
     6721 aaaatccgaa tttttgacaa caattcactt cccgagtaca aaaaaagact aacagagtat
     6781 aggaaatatc cctacatcga tatctatttt catgatgaaa attccggatt tggttatgga
     6841 cataatcaca atctgatagc tagcgattct cgctatggca ttatttgtaa cccagatatt
     6901 ttagtggatg aagagacagt tacagcattg gtcttgttat tgaaagaaca tccggaatgt
     6961 gcgatgttag cacctaagat tcttaatgaa gatggaacaa ctcagcacct catccgtgag
     7021 cagctggctg tttttgatta cgttttgcgc tttgtgcctt tcaaatgggt caaaaaaaag
     7081 tttgacaaac gactggctgt gtttgaatgc cgaggattgc ctactgatgc taatagttat
     7141 gtacggatga tctcaggtag ttttatggta gctgatattg ataaatttaa agagataaag
     7201 gggtttgatg agcgtttctt catgtacttt gaagacaacg acttgtgttt gagttttgaa
     7261 aaagcaggtt acaagttatt gtacacaccc ttttatgcag ttatccattt ttacgggaag
     7321 ggtgcgcatc gaaatgcaaa actgtttcgc gtgtttttga cttctatgat gaaatttttc
     7381 aataagtggg ggtggcgttt tttctgatga aaccagaaat attagtagtc gttgtgcttt
     7441 atcagcaact attcagtcaa tctccagctt atggaccatt aagcaaagca cttagcgaaa
     7501 agcaaattca gcttattatt tacgataata gtcctcaaag gcagcaaaat gagctgtttg
     7561 aaaaagaaaa tatcgtttat catcatgatc cgcaaaatcc tggtttagcg gtggcttata
     7621 attttgcgtt gtctcaagca gatgaaggaa cacgttgtct cgtcactctg gatcaggata
     7681 cgaggctagt cgacgattat tttgaactat tgcgtaaagt aacctttaca gatgaatgtg
     7741 ttgctgcagt tccgatgatt ttttctggga gccgacaagt ttctccccta tattcagatc
     7801 gttatatcaa tcgtacagct caagcagtag aagttgaagg cccaacagct gaacgaatca
     7861 tggcaatcaa ttcaggtgtt gcctggtctg tcaaatttct aaaaaagatt ggcgggttta
     7921 atcctgcttt ttctttagat tttttggatc attggctgtt ttggaaagtg gatcagttgg
     7981 aaaaaactgt ggagatcctt cctgtacgaa tggaacatga tctttcggtt ttagactatg
     8041 aaaaagtttc aagtaatcga taccgttcta ttttacaagc agaaaatcga ttttatcatg
     8101 aatatgatca aaggcattta tccagtcacc gacgacaatt attgttaaga acagctaaac
     8161 agttcttgac cgtcaaaaac cggcatatct ggcggatgac tttgcgctca tatgttaaga
     8221 attggaaggt gtgaattcgt gcgttcggtt tgtatagcta cctttaatgg aggcagatat
     8281 ttaagagagc agttagatag tattttatct cagctttcag cagaagatga agtagtcatt
     8341 tctgatgatg ggtcagtaga tgatacatgg gatatattaa ctgaatacgc agaaaaagat
     8401 aagcgaatcc agcttttttc ggggcctcgt caaggattga tcgctaattt tggttatgcg
     8461 atccagcaga cgaaaggaga tctaatcttt ttggcagacc aagatgatgt ttggttggag
     8521 acaaaagtga aaaagatcac tgactatttt gagcagaatc cggatcagct agtagtagtt
     8581 tctgatttaa tcattgtgga cagcgagctg caagagatcc atgattcgta tttttcgttt
     8641 cgaaattcca aagaaggatg gcttaataat gtgataagaa gtcactatat tggtgctggt
     8701 atggctttcc ggtcttcttt aaaacccgat attttgccga tcccgtcaga agtgccgatg
     8761 catgatatgt ggattggttt gctgggagga aagaagactg ggttcctaag agaaccgtta
     8821 actctgtacc gaagacatga tttaaacgcg agtgagattg aaacacattc taaattacgg
     8881 caaaaaattt cttggcgtgt tcatctgatt acggcgttga tcaaacgaaa atggtttaaa
     8941 cgttgataaa agatgtttaa atccttaata tttccatgac aaatataaca attgatgaga
     9001 taataacaaa gtgaaatttg aaatcaaaaa ggagagcaga tatccatgaa gggaatcatt
     9061 cttgctgggg gcagcggaac acgtctgtac cctttaacaa aggcaacatc gaaacaattg
     9121 atgccgattt atgacaaacc aatgatttat tatccaatgt ctactctgat gttggcggga
     9181 atcaaagaaa ttctgattat ttcaacgcca caagatacac cacgtttcaa ggaattattt
     9241 ggaaacggaa atgatttagg actgcagatc gaatatgcag tacaagaaag tccagatgga
     9301 ttggcacaag cgtttatcat tggagaagaa tttattggag atgatagtgt ctgcttggta
     9361 ttaggggaca atatttacta tggtggcggt ctgtctaaaa tgttgcaacg agcagcttca
     9421 aaagatacag gcgcgacagt atttggctat catgtcaatg atccagaacg ctttggtgta
     9481 gtagaatttg atgagaatat gcaagctttg tcgattgaag aaaagcctgc tcagccaaaa
     9541 tcaaattacg ctgtaactgg cctttatttt tatgacaatg aggtaatttc tatcgctaaa
     9601 ggtatcaaac cttcagaacg tggagaacta gagattacgg atgtcaataa agcatatttg
     9661 gataaaggaa aactatccgt agaacttatg ggacgcggat ttgcttggct tgatacagga
     9721 acacatgaat cattgcttga agcatctacc tttatcgaaa caattgaaaa acgtcagaac
     9781 ttaaaagtgg cttgtttgga agaaattgct taccgtatgg gctacatcga taaggaacaa
     9841 ttgctggccc ttgcacagcc attgaaaaaa aatcaatacg gtcaatattt attgaatttg
     9901 gccgctgaat aaggagtcct tacagatgaa agtaacagat acaaaattaa cagatgtcaa
     9961 aatcgtagaa atggacgtct ttggcgatca tcgcggtttc ttcacagaaa gttattcaaa
    10021 agcaaaattt gcagaacatg gattgaaata tgactttgtt caagacaacc attcactatc
    10081 agctgaagct ggtgtccttc gggggcttca tttccaaaaa ggagaagctg cacagacaaa
    10141 attgattcgg gtagtcactg gagcagtttt agatgtagta gtggatatcc gcaaaggtag
    10201 cccgacttat ggtcaatggg acggatttat cttatctgaa cataatcatc gacagttgct
    10261 tgtacctaaa ggatatgccc atggattcgt tactttgaca ccaaatgtga acttccttta
    10321 taagtgtgat aattactata atgcagaagc agatgggggc atcgcatttg atgatccaga
    10381 tttagcgatt gattggccaa ttgatccatc aagagcgatt atgtcggaaa aagatcaccg
    10441 tcatccgaca ttaaaagaat ttgaagcaga aaatccattt gtttacggag aaatctaaga
    10501 attaaggaga aattttctta tgaaaaacat cattgttacc ggaggtgccg gattcatcgg
    10561 ctctaatttc gttcattacg tggtaaacaa tcatccagaa gtgcatgtca ctgttttgga
    10621 taaactgact tatgcaggaa acaaagagaa cttggctgga cttcctagcg atcgcgtaga
    10681 attggtcgta ggagatgttg cagatgcaga attagtggac cgtctagtaa aagaagcgga
    10741 cgcagttgtt cattacgcgg cagaatccca taacgataat tcattaaaag atcctttccc
    10801 atttgtacaa acgaatatca ttggtacgta tacactttta gaagcttgcc gcaagtatga
    10861 tgtacgctat catcacgtat ctactgacga ggtttacggc gatcttccat tacgtgaaga
    10921 cctgccagga catggggaag gcgaaggaga aaaattcact gcggaaacac catataatcc
    10981 ttcaagtcca tattcttcta caaaagctgg ttcagatctg ttagtaaaag catgggtgcg
    11041 ttcttttggc ttacgtgcaa ccatttcaaa ctgttcaaac aactatggtc cttatcagca
    11101 tattgaaaaa tttattcctc gccaagtaac gaatatctta agcggtattc gtccaaaatt
    11161 atatggcgaa ggaaagaatg ttcgtgactg gatccatacg aatgatcatt cttcagcagt
    11221 gtggctgatt ttgacgaaag gcagaattgg cgaaacctat ctgatcggtg cagacggtga
    11281 agaagataat aagaccgtga tggaattgat cttagaaatg atgggtcaac caaaagatgc
    11341 gtacgaccat gtaaacgacc gtgcaggaca cgacttgcgt tatgcaatcg attcgacaaa
    11401 attacgggaa gagttaggat ggaagcctga gtttacgaac ttccgtgatg ggttggctga
    11461 cacgatcaaa tggtacgaag aacatgaaga ctggtggaaa aaagaaaaag aggccgttga
    11521 agcagcatat gccaaaaatg gacaataata cagagaaaat gtcactgtat taatggaaaa
    11581 acacatgtga ggcaggcgct cgcctgtctc ttttttaaaa taaaaatcaa ggagcggata
    11641 atcatatgtt tttattaact ggaggaaatg ggcaactagg tacagaattg cgccatttat
    11701 tagatgaaaa aaatctgcaa tatgtttcaa cagatgcaaa agacttggat atcacagatg
    11761 ccgagaaaac aatggcttac atcacagaat taaaacctga tgttattttc cattgtgcag
    11821 cttacacagc agtagataaa gcagaagaag aagcaaaaga attagatgag aagatcaatg
    11881 ttgatggtac aagaaatgta gcacttgcag caaaagctgt gaatgctcaa ttcgtctata
    11941 tcagtacaga ctatgttttc gatggaaaaa acaaaaatgt agaatacgaa gtagacgacc
    12001 aaacgaatcc actaaatgaa tatggtcgta cgaaattatt aggcgaaaaa gcagtagaag
    12061 agattttaga agactattat atcatacgaa cttcttgggt tttcgggatc tatggacaca
    12121 atttcgtctt cacgatgcaa cgcctagcgg aaacccgcga caaactgact gtagtaaatg
    12181 accagtttgg gcgaccaact tggacacgta ctttggcaga atttatggta tatgtcatcg
    12241 aagaaaaagc accatttggt atttatcatt tgtcgaacga aaatagctgt tcttggtatg
    12301 aattcgcaaa agaaatattg aaagatacag atgtagaagt tgcacctgtt acgtcagaag
    12361 aatttccgca aaaagcaaca cgtccgcagt attcagtcat gagcctgaaa aagacagaag
    12421 agttaggatt tgtcatacca acttggcaag aagcacttgc gcaaatgctg gaagctgcca
    12481 aaaaaatgaa taagtaattt ccttttatca aatagaattt ggagcatgat atggaaaaac
    12541 aaacaagaag tgcacgacga aaagaaaagc caaaagcgaa ccaggcagat tcgaatttgg
    12601 tgcttgacct gtttctaaaa ctccgctatc ttattggcgt tttagtcatc gtggtcatcg
    12661 ttacttttaa tttaaacgga agttcacttg gtgtttggga taaatatgtg tcgcaaagag
    12721 acgatgggaa aaaaactgat gtgatttttg gacagaatcg ggaagtgcgg tcagacgaat
    12781 ggctggtgca gacacctttt tacctctcac aagctgaaga ggactttccg ttggtgaacg
    12841 aggattattc attaaacgga caaaacatga tcattgcgta taattctcct gtaaaggata
    12901 ttacggttat cggaaaacca ttcaactggg gattcttttt cctcggaaga gatcgaggac
    12961 tttcctttta ttgggcgatg aaattagtcg tcatggtctt gcttggattc gaagtactga
    13021 tgatattaac gaagagaaaa aaagctctat cgctaatcgg tgcatttgcg ctgacatttt
    13081 ctccagcagt ccagtggtgg ttcatgcaac atgtgggcga tttgattttc tttactttgg
    13141 gactgatgac tgctttttat cattatttct acaatcatga taaaaaatgg ctacgaacgt
    13201 tgatgatgct tttggtggtt attttcggta ttgggtttat tttagtgatt tacccagccc
    13261 atcaagtgat gctggcgtac ttgctgattt tttattttgt tggcctgctt atttactata
    13321 gcaagaaagt ttcatgggat ctgttggatg tagtgttgat tggaggggca gttttattta
    13381 ttggcggagt catggttcat ttctggctaa cgtcaaaaga cgcattgtta gcttctttga
    13441 ataccttata tccaggaaaa cgggtaagta ctggaggaaa gtggacgatt ggcgaatttt
    13501 tttctttcct tacaaattgg aaaattcctt ttgaagatat caactattcg aataactctg
    13561 aagtggccct gttctatcac ttttttccaa ctgtattcct agcaagtcca tttgtgttat
    13621 ttggcaaaaa agatagcgaa caaaagttac tgggacgtat tttgatgatt ttttgtctgt
    13681 tttctatctt ttggattacc gttgggttgc caaaatggct agcagaaatc actctgctgt
    13741 cttatgttcc tccattaaga gccatcctta cttttagttt tgcggcttgt ttattatcga
    13801 tctggtttat cgcttatatt tggagagaag atgttattcc tatttggtat aaattcattt
    13861 tgttggcagt aaatgcatgg tcttatttct atgcgattac gcattcgaaa atggataatt
    13921 atttttcgga ttttgaaacc atcgcagttg ctgtgttggg aacagtgatt ttagcttttg
    13981 cattatttgg ctggagacgc ttgttttacc tcgcttttgc cgccttagtt atcgtatctg
    14041 gctttttcgt caatccagtc gtagaaggta caggagcgat ttttgaaaaa acactggcaa
    14101 aagaaatcca aaaaatcgat caacaagatc ctggtaaagt ttggttgtct gaagatgaat
    14161 tatataactt caccccaaca ttgggagtga aatccttcaa tacagtacgc ttttatccag
    14221 atatagctgc atggaagaaa atcgatccga aagaagaata cgagaagtat tataatcggt
    14281 atgctcatac aagagctttt atcgctaagg aagatacaaa gttcatttta gatcgtccag
    14341 atatgttttc ggtcacgttg aattttgaag acgcagaaaa attagggatc gactatgtga
    14401 tcagtaaacg accattaact gattacaacc aattatatga agcgcagttc acgcagctat
    14461 atggaccgga taaagacggt tatatgattt ttaaagtaga atatccggat tatccagatg
    14521 taccacaaac acaaactcag gaaaatcagc tagtcgtaca gtaataggct agctgagaat
    14581 aatcctgaaa tgttagtaga aaggagagtg gagataattc aagcaatcgt acaaaaattt
    14641 gtcaacaaaa tgagtgtcgg tttcttgctt ttgttactga cgctagtctt ttttgtttgg
    14701 acagcagggt taggttttcc agcaactttg tttatatata acaatagttc attacttatc
    14761 gcttttagtg tggctatttt gctcatttta aatgtttata aagcaaaagg cgtcgatttt
    14821 ctttatctag gtgttgcgct tgcccttttc attttctttt cttactttcg ggaattaaga
    14881 aatgagtctt tatttggaga cttactgttt cctttgatta ttttattttg tttagtaatt
    14941 aaatggatcg agtggacaaa atgggatcgc ggtatttatc tgattgtctt ttcggtcttc
    15001 ctcggaatca cgttatatcg tgtatttaca gagatccaag taccagaagg acaaagcatc
    15061 tgggctccag gcaattcgct ttctgatatt tggatcaata cgaatacaat cggaagttct
    15121 ttgatgactc ttgctttatt gatcagtgga tttgccagtt cttttgaacg atggtatgta
    15181 cgaatcatcg gtgcagtagc agttgttgca gcttttctcg ggatttgggt ctgccaatct
    15241 agaggtgcat tagtcgcgtt gattgttttt gcgatattgg atcttttacc taaatcgttg
    15301 atgcgtgtca ttcgtgcgcc atttattgct tacacggtta cgattctttt agctttgccg
    15361 atttcttatc tggcggctgt ctctgaaaaa gtcaatttgt ttaccggtcg agaagatatt
    15421 tggcataaat tctatcagac gctaggagaa aaatctgaac aaattttact aggaatgaaa
    15481 acatttatct tccaacgagg aaaccacaat agttataatt ctattttgaa tatctatgga
    15541 ttgataggat ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg
    15601 aaagcagatt tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg
    15661 cagtcattta tggaggatac attgacttca tacccatggg ttccgattat ttatatcctg
    15721 ttggctatgg ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg
    15781 gaagaggcat atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc
    15841 gctcattctt ccaggatcca acgctatcat tgataggcac aaaa
//
LOCUS       DADVXB010000063        14955 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.064, whole genome shotgun sequence.
ACCESSION   DADVXB010000063 DADVXB010000000
VERSION     DADVXB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.064"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            236..1180
                     /gene="mvk"
                     /locus_tag="KB902_001548"
     CDS             236..1180
                     /gene="mvk"
                     /locus_tag="KB902_001548"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBB6808383.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            1173..2150
                     /gene="mvaD"
                     /locus_tag="KB902_001549"
     CDS             1173..2150
                     /gene="mvaD"
                     /locus_tag="KB902_001549"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBB6808384.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            2163..3248
                     /locus_tag="KB902_001550"
     CDS             2163..3248
                     /locus_tag="KB902_001550"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBB6808385.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            3245..4309
                     /locus_tag="KB902_001551"
     CDS             3245..4309
                     /locus_tag="KB902_001551"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBB6808386.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAAGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(4558..5361)
                     /locus_tag="KB902_001552"
     CDS             complement(4558..5361)
                     /locus_tag="KB902_001552"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBB6808387.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYICDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(5381..6223)
                     /gene="kduI"
                     /locus_tag="KB902_001553"
     CDS             complement(5381..6223)
                     /gene="kduI"
                     /locus_tag="KB902_001553"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBB6808388.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(6239..7246)
                     /locus_tag="KB902_001554"
     CDS             complement(6239..7246)
                     /locus_tag="KB902_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBB6808389.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWTLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(7253..7897)
                     /locus_tag="KB902_001555"
     CDS             complement(7253..7897)
                     /locus_tag="KB902_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBB6808390.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(7997..8755)
                     /locus_tag="KB902_001556"
     CDS             complement(7997..8755)
                     /locus_tag="KB902_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBB6808391.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDESKEQIISALKQTKSEIEQRIQK"
     gene            complement(8882..9286)
                     /locus_tag="KB902_001557"
                     /pseudo
     CDS             complement(8882..9286)
                     /locus_tag="KB902_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(9374..10630)
                     /gene="rhaA"
                     /locus_tag="KB902_001558"
     CDS             complement(9374..10630)
                     /gene="rhaA"
                     /locus_tag="KB902_001558"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBB6808392.1"
                     /translation="MNTIEKNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDGR
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(10627..11610)
                     /locus_tag="KB902_001559"
                     /pseudo
     CDS             complement(10627..11610)
                     /locus_tag="KB902_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
     gene            complement(11606..12025)
                     /locus_tag="KB902_001560"
                     /pseudo
     CDS             complement(11606..12025)
                     /locus_tag="KB902_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
     gene            complement(12254..14851)
                     /gene="adhE"
                     /locus_tag="KB902_001561"
                     /gene_synonym="adhC"
     CDS             complement(12254..14851)
                     /gene="adhE"
                     /locus_tag="KB902_001561"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBB6808393.1"
                     /translation="MAKVMEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
BASE COUNT         4111 a         3263 c         2815 g         4766 t
ORIGIN      
        1 aattgtattt ttttctagtc aaagaagaaa aaaagtcaaa aaattcttaa gaaaaaagtg
       61 ttttttcttt agaaaacgta ttcttagttt tacttctgag atggttttag taaaataaag
      121 gaggaatgtt ttttgagacc cttagtggac aaaaaaattc gtgaagcagc gcaactcgtt
      181 ttgggcgctt tattttttgc ttaaaaatca cttttacgtg agaaggagtt agattatggc
      241 aaactatggc caaggagaat caagcggaaa gatcatattg atgggcgagc acgcggttgt
      301 ttatggagaa ccagcgattg cctttccttt ctatgcaaca aaagtcaccg cattccttga
      361 agagctggat gcaatggacg atcaactggt ttcttcctac tattcaggaa atttagccga
      421 agctcctcat gcattaaaaa atatcaaaaa attattcatt cacttaaaaa aacagcatga
      481 catccaaaaa aacttgcaac tgaccattga aagcacgatt cctgctgaac gtggaatggg
      541 atcaagcgct gcagtcgcca cagcagtcac tcgtgctttt tatgattact tagcatttcc
      601 tttgtctcgt gaaatactat tagaaaatgt ccagctttcg gaaaaaatcg cccacggtaa
      661 tcctagtgga atcgatgcag ccgctactag cagcttgcag ccgatttatt ttacaaaagg
      721 gcatcctttc gactactttt ctttgaacat cgatgctttt ttgattgtcg ctgatacagg
      781 aatcaaagga caaacaagag aagccgtcaa agatgtcgct cacctctttg aaacccagcc
      841 tcatgaaact ggacaaatga tccaaaaatt aggatacttg acgaagcaag caaaacaagc
      901 aatcattgaa aattcaccag aaacgttggc acagacaatg gatgaatcac aatcacttct
      961 ggaaaagctg acaatcagca atgattttct taatctattg atccaaacag caaaagatac
     1021 cggggcattg ggtgccaaat taactggcgg tggacgcggt ggctgtatga ttgcattagc
     1081 acaaacaaaa acaaaagccc aagaaatcag tcaagcactt gaagatgcgg gtgctgctga
     1141 aacttggata caaggattag gagtacatac ctatgtttaa aggcaaagca cgcgcatata
     1201 ccaacattgc tctaatcaaa tattggggta agaaaaacga agaactcatc cttccaatga
     1261 acaacagcct ttcgttaaca ttggatgcat tttatacaga gacagaagtc atcttttctg
     1321 atagctatat ggtagatgaa ttttatctag atggcacctt gcaagacgaa aaagcaacaa
     1381 aaaaagtcag tcagtttctt gacctttttc gtaaagaagc cggcctctca ctaaaagctt
     1441 cagtaatcag tcagaatttc gttcctaccg cagctggatt agcctcctct gccagcgggc
     1501 tagctgcttt agcaggagct tgtaatactg ctcttaagct tggattagac gatctctctc
     1561 tttcaagatt tgctcgacgc gggtctggtt cagcttgccg aagtattttc ggtggtttcg
     1621 tcgaatggga aaaaggccat gacgacttaa gttcttacgc taagccagtc ccttccgatt
     1681 ctttcgaaga cgatttagca atggttttcg ttttgatcaa cgaccagaaa aaagaagtgt
     1741 ccagcagaaa tgggatgcgt cggacagtcg aaacatccag tttttatcaa ggctggttag
     1801 attccgttga aggggatcta tatcaattga aacaagcaat caaaacaaaa gatttccaac
     1861 ttctcggaga aacgatggaa agaaacggac taaaaatgca tggaacgact ttagctgccc
     1921 agcctccatt cacttactgg tctcctgaca gcttaaaagc gatggatgcg gtgcgacaat
     1981 tgagaaagca aggcattcca tgctacttta cgatggatgc tggccctaat gtcaaagttt
     2041 tagtggaaaa cagccattta tctgaggtac aagaaacatt taccaaatta tttagcaaag
     2101 aacaagtaat tactgcccat gctggtccag gaattgcgat tattgaataa agggagattt
     2161 ttatgattga agtatctgca ccaggcaaac tctatattgc cggagaatat gcagttgttg
     2221 aaacaggcca tccagcagtt atcgctgcag tcgatcaatt cgtgacagtc actgtagaat
     2281 ctgcacgaaa agtcggaagt atccaatctg cacaatatag tgggatgcct gtacgttgga
     2341 caagacgcaa cggagaatta gttttagata ttcgggaaaa tccttttcat tatatccttg
     2401 ctgctattcg cttgactgaa aagtatgcac aagaaaaaaa cattctttta tccttttatg
     2461 atctgaaagt aacaagtgag ttagacagtt caaatggccg gaaatatgga ttgggttcta
     2521 gcggtgccgt gaccgttgca acagtcaaag ccttgaatgt tttttacgcg ttgaatttat
     2581 ctcagttgga gattttcaag attgcagcac tagccaattt agcagttcaa gataatggtt
     2641 cctgcggcga catcgctgct agctgttatg gtggctggat cgctttctca accttcgacc
     2701 atccttggct ccaagaacaa gaaactcagc attctatcag tgagttactt gccctggatt
     2761 ggccaggtct atccattgag ccattgattg ctcctgaaga tttacgttta ttgattggtt
     2821 ggacgggtag ccctgcctct acttctgatt tggtcgatca agttcaccgt tcgagagaag
     2881 ataaaatggt ggcttatcag cttttcttaa aaaacagtac agaatgtgtc aacgaaatga
     2941 tcaaagggtt taaagaaaat aatgtaacgt tgatccaaca gatgattcga aaaaaccgac
     3001 aattactgca tgatttatct gcaatcactg gggtcgtcat cgaaacgcct gctttgaaca
     3061 aattgtgtaa tttagctgaa cagtatgaag gagccgcaaa atcttctggt gcaggtggtg
     3121 gcgattgcgg aatcgtaatt gttgaccaga aatctggcat tcttccttta atgagtgcat
     3181 gggaaaaagc agaaatcact ccactgccgt tacatgtcta tagcgatcaa agaaaggaaa
     3241 accgatgaat cgaaaagacg aacatgtttc actagctaaa gcctttcatg ataaacaaaa
     3301 aaacgaattt gacttcgtac ggatcatcca taaccctttg ccgcaaatag cagtttctga
     3361 tgttgatcta agcacacagg cagctggttt tacactaagt agcccgtttt atatcaatgc
     3421 aatgactggc ggaagcgaaa aaacaaaaaa aatcaaccaa gatcttgcaa tcgtcgcaag
     3481 agaagcagat ttgatgattg ccactggttc agtcagcgct gccttgaaag acccttcttt
     3541 agctgatact tatacgatta tgcgacaaga atatcctcac gggaaaatca ttgccaacat
     3601 cggtgcaggg acttctgtcg aaagagccaa agaagctatc cgattgtttc acgcagatgc
     3661 cttacaaatt catttgaatg cacctcaaga gttggttatg cctgagggag accgtgattt
     3721 taccaattgg aaagtactta ttcaagagac tcaaacagcc attgacgtcc ccctcatcgt
     3781 aaaagaagtc ggttttggca tgacaagaga aacgctcaat gatctagctg ctttaggagt
     3841 tcatacagtt gatatcagcg gtcgaagcgg aacaagcttc acccagatcg aaaacgcccg
     3901 tcgctccaag cgggaactga gttatttagc tgactggggg caatcgacag tctcttcatt
     3961 gcttgaagca aatgaagcag acacttctat ggaaatccta gcctccggag gtatccgcaa
     4021 tgcctatgac atatttaaag ccctttgtct cggcgcaaat gcagtgggta cttcaggaac
     4081 cgtactgacg catctgatga atcatggcgt agaagaaact attatactga tgaagcaatg
     4141 gcaagaagag cttcgtctgc tttatactat ggtcggcgca acgaataccg cggccctaca
     4201 ccaacaatct ctgatctttt ccggaccagt gaaggattgg tgcgaagcaa gagggatcga
     4261 cttagtgaag tatggaagac gcacagaaaa gagcgtggga caaaagtaaa gaacactttt
     4321 gtctcacgct ctaaacacgt acaaacggcg gaagcaaaag caactccttc ggaaataagc
     4381 tgaaattcac aaaaatttga aaagcaattt tcgtgaattc cttcttattt cttggagtta
     4441 aacgcttctg tcccagcctc ttttttcgaa taaatgatgt ttaatcagct gtccttcggt
     4501 attcgttcaa tccgctgatt tcacaacctc tccactaaac agtgtactaa agctctttta
     4561 aggttgtttt ccgatatagg caagtatgcc tccgtccaca tacaagacat ggccgttaac
     4621 gaaatcagat gcgctagaag ccaagaagac agatggtcca gccaaatcga ttggctcgcc
     4681 ccagcgtgct gctggcgtac gtccaacgat aaattgatcg aatggatgac gttcaccgtt
     4741 ttcttgtgtt tcgcgtaatg gagcagtttg cggtgtagca atataacctg gtccaattcc
     4801 attacattgg atattgtatt gaccgtattc agaagcgatg tttttcgtca gcatttttaa
     4861 tccgcctttt gccgcagcat aagcactgac cgtttcgcgt cctaattcac tcatcatgga
     4921 gcagatattg atgattttac cgccgccttt ttcgatcata tccggaataa ctgcttttga
     4981 aacgatgaat ggggcattta aatccacgtc gattacttgg cggaagtctg ccgcatccat
     5041 ttcgatcatc ggtgtccgtt tgatgatccc tgcattgttg actagaatat caactgaacc
     5101 tacatcttct ttgatctgtt gaaccatcgc ttgaaccgct tcttcatcgg tcacatcgca
     5161 gatataacct tttgcatcga tgcctgcttc tttataatgc gctatacctt catcaactga
     5221 ttcttggttc aagttattaa atacgatttt tgctcctgct gtagctaaag agcgtgcaat
     5281 ctcaaatcca ataccataga cagcaccggt gactaatgct acttttccat ctaaacgaaa
     5341 catatccata ctaaattcca tcattttctc tcccttatgc ttattttaat tgatccattt
     5401 gcaccatatc catgtctgta taggtgatat tttctccgca cattgcccag atgaatgagt
     5461 aattgcttgt acctacacct gaatggatcg accagcttgg cgaaataatg gcttgttcat
     5521 tgtctacaac taaatgtttt gtttcatctg gtttgcccat catgtggaac acacgtgtat
     5581 cttcattggc ataatcaaag tagacataag cttccatacg acgttcatgt gtatgacaag
     5641 gcatcgtatt ccaagcactt cctggttcta aaatcgtata acccatttgt aattgacagc
     5701 tttcgcatac atttggatgg atgtattgat agattttacg ttcattcagt gtcaggcctt
     5761 caccagtttc cattggtttt acttggtcga tactgatttt tacatttgga tatttatgat
     5821 gagctggaac agaactaata tagaatttag ctgggttttc agcatcttga gaagaaaata
     5881 caacatgtcg tgtttctttt ccgatatagt atccgtcttg ttttttcatt tcttcttttt
     5941 gcccatcgat ctcgatgaat cctggtccac cgatattgat cacacctagt tcacgacgct
     6001 ctaagaagta atcaacacct agttctttgt ctaatgtgat ttctaattct ttttcagtag
     6061 gtgtcactcc accaaagatc attcgatcgt tgtgcgtata agtcaaactg attttccctg
     6121 gttcaaatac cttttctact aaaaattctt ttctcaattg ttccgttgaa taatgacgga
     6181 tatcttctgg actgtgtgta taacgtgttt ccatttcttg cattttcttc tactccttct
     6241 atcgaatgat ttttccagag ccgcatgcta aaaattgtgc gacttcttct tgactgaatt
     6301 ggttgcagtc cccatggatc gtatgcttca aggcagaagc tgccgtagca aaatcaatga
     6361 tttcttgcgg agacatattg gataaaatcc catggagcac gccacctgca aaagcatctc
     6421 cgccacctac tcgatccacg attggggtga ttctatggac ttgggattcc acatattcat
     6481 ggttcatcca caatgtcccc ttcaattcat tttcacttgc tgaatgaacg gtacgcttgg
     6541 tcgaataaaa cacctgaata ttcgggaact tttcctgcat tttttgataa taataaatta
     6601 gaggttgttc ttctgcttct ggcgctttct cgatacctaa caaataaaga gcatccattt
     6661 ttccagctga gcagatatct actaaaggta aaagctgatg gattacttcg ctggcttctt
     6721 gctgtgtcca taattttcca cgatagttga tatcgaagct gatcaggcag ccagcttttt
     6781 ttgcagcttc tatcacctgt ttcgtcattt tttgccattt tttagacaaa gctggggtga
     6841 ttcctgaaac atgaaatata tctattcctt ggaataactc ctctagcgtc cattccaaat
     6901 gatccatttc agcaaaactt gatccggcac gatcatagat cactgaggcg gcgcgttcgc
     6961 cactaccagt ttccatataa taagtaccta gtcttgatcc accagataat acctgtttcg
     7021 tatctactcc ataacattgc aagtgctttt tgactgcttt tcccaatgcg ttatcaggta
     7081 cttttgtagc aaaaatcgct tcatgtccgt aattagctaa agaaattgct acgtttgctt
     7141 cccctccgcc ataatgggca gcgaatcgtt cacttgaatc gatacgggtt ccctgctctg
     7201 tggacaatcg caacatgatt tctccgagtg tcactacttt tcccataagc agctacctct
     7261 tgatttcttt catttttgct gcatactgtt gcgcgacttc cgttactttg tcgaaatctc
     7321 ctgtagctgc gggtgctaaa aggttcccac ctactccgac tgttacgaca ccagcatcga
     7381 accactcttt catattgtcc agactcacac cgccagttgg catgatattg acttgaggca
     7441 tcggcgcctt gaaggcagaa atgatacttg gtccataagc gcttccagga aatagtttga
     7501 cgatatctac cccgcttttc agcgctgttt tgatctcggt aatagtcata catcctggta
     7561 agtaaggaat ttgatacaga ttacacatct ctgccgtttc ttgatcaaag gaagggctaa
     7621 caatatactc tgcgccagct aagatagcca agcgagctgt gacagcgtct aatactgtgc
     7681 ctgcgccaat cactatttct ggttggtctt tgtagaatga caaaagttct ttgattactt
     7741 gatctgcttg agggactgta aaagtcaact caataccagt tagaccacct ttgatgattg
     7801 cgtggcaagc attcaaagct tcttctttgc tttttccgcg taccaccgca atcactccgg
     7861 cgtttttcaa tcgagataaa atatcaattt ttttcatctt ctccacctat ttcctatttg
     7921 gaaattttat tttataactt ggaaatctat acccatatta tacggcagaa aagaaaaatt
     7981 gcaaacgctt ttttcattat ttttgaattc tttgctcgat ttcgcttttt gtttgcttga
     8041 gggcactgat tatttgttct tttgactcat ctgttaaacg atatttcggc atacttacac
     8101 taaatgcacc aatgatttgt tcgtttttca cgattgaggc tcctatacaa aaaatatcac
     8161 gttcgatttc ttcatcgtca aatgcgatgt gggtttcttt taccgtttgg atttcctttt
     8221 tcaaccgtaa tgcattggtg atcgtatatt ctgtgtaagg gatcaacgga tgcttttcaa
     8281 gataatcagt gtactgctct tcactgaatt ctgctaatac ggctttgccc atcgcagaat
     8341 tgtataatgg tcgggtgatt ccgatttttg aagacatacg gatcgtttga tgttttggat
     8401 ctagtttgtt cacgtacaaa atctcattgt tgtccaatac ccctaagtgg atagtctcat
     8461 cgatcttttg ctgcagctgt tctaaaaacg gtaaagtcaa ctctaccaaa tcgatttgtt
     8521 caatgttttt attcgcgtag cgaataagct ttgcacctaa acgatagttt ttctctgaat
     8581 ttttatttac gtagccgatc atcagcaaag tatctagtat tttcaagact gtagaagagg
     8641 tcattcccac accctttgcg atcgtctgca aagagacatc ttggttttcc gctaaatagt
     8701 ctagtatttt agaggctttg atcaatacag ttccataagg ctttttattt tccatataat
     8761 attctcctat ttctttataa gaaaaattat agcggaaata ccatcaattt aaaagagata
     8821 tccagatata aactaccatt tctctttaca ggcaatttaa tgttgaagat ccgcttcgtt
     8881 tttacatcaa actttgatat aaagcaatga tttcttctac tgtcgtttct cttggatttc
     8941 ctggtgtgca tacatctcgc aaagcatctt ctgcaattgc tgggatatct gcttctttta
     9001 cacctaattc agaaatggtt tctgggattc caaccgcttt gctcaaccga tcgatctcac
     9061 cacaagccgc ttctcttaca tcttctaaag acatttcagc tgctccttta atccctagaa
     9121 caagagcgat ctcacggtac ttttctccag tatattcttt gttatatttc atgacagttg
     9181 gcaaaagtgc tgcacacgct acgccatgag gaatgttgta ccatgcactt aacgggtgag
     9241 ccatcccgtg taccagtcct aaaccgacat ttgagaagcc cattccaagc gataaagatt
     9301 cgacgtcgtt tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa
     9361 tatagccaca ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt
     9421 ccagccaatc caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg
     9481 catacgggaa atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca
     9541 gctccatttc tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg
     9601 tatttctcgt accgatgacc caagcagcga tacggttgat cgttgcgtca aagaaatcca
     9661 gaccgatatt tgttttttcc aacaattcgt tacggactag ttctttagcg atttcctgca
     9721 attcatcatc catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca
     9781 gcatgattcc tttactgaat aaagctaatg aagataattt attggaaatc acttctgttg
     9841 gatgaaaatg tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat
     9901 aaaattcatg ggagccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta
     9961 ctgcatcttg tacataccgt ccatctaact cttctgtaaa aatttcatcg agtgattcca
    10021 ttaaacgttc ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc
    10081 aaaagttatt gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc
    10141 ttcttttccc gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa
    10201 agccgtcttt catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt
    10261 ctttttttgc ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga
    10321 cagattcttc tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca
    10381 acgaataagc cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa
    10441 aattccctgt cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga
    10501 catcgtctcc ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag
    10561 catctgtatc tacaccgata gttgcatatt tttcttttgc ttgttcataa tttttttcaa
    10621 tcgtgttcat acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt
    10681 attttcatct gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg
    10741 ttctatattc gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt
    10801 ggcttcacta ggacctgctt ctacaatgat tccggcataa tctgctgtca attgattcag
    10861 tagacgatta ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa
    10921 gtgttctact ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg
    10981 agcgatagct cccggtgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat
    11041 ctcttctatc atattttggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg
    11101 cagcggtttt tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg
    11161 cattcgggca acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt
    11221 gttatgggca ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc
    11281 gatctttgtt tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc
    11341 tccttgacct ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa
    11401 ggtcacatct ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt
    11461 tcccggctct gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc
    11521 tatttcccat tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc
    11581 cgtcaccatg ttaccagtaa agacataacc cgtcttcatt tgtccgaggc atgtcattca
    11641 tgacccattc tgcccattgt tctaaataag gcaaatagcg tgaatctttc gtgtcttcat
    11701 acaagtaagc catagtcaat agcggtgcta ttgtattgac gtttttgggc ggagcgcctt
    11761 cttccatacg atcctcaaac cattcattga ccacttgata agcgcgagga ttttttgtca
    11821 tctggtaatt tttataaata ccatatagac cgacaccttg tggccaattc cacactgtcc
    11881 agcttttgtc atctactttc agtccatcaa agtccaacaa aaattcacca ttatcgtctt
    11941 tgatcgttgt caggttttca acgagcaggt caattttttc tttcactaat tctttaggta
    12001 caaaaatctc ttctttaata atcatcttta cgccaccttt ttaaacgctt tcattttata
    12061 tccttaatat agcagtaata ccgtccacta tgaatatcgc tttttgaaca aaaactgtct
    12121 aaaattgacc taaatgttaa ataacaaaag taactttcag ttacttggaa attaaaaaaa
    12181 gaacttggag aaacaacgtt ttccaagttc tttttcatct attttcttat cttttttcta
    12241 cgctttcttt tgcttatccg ttgtaagcat caatgatgat ctgtttcaat tcagagatca
    12301 atggttcttt cggattagct gtcgtacatt ggtcttcgta agctaattca gccatacggt
    12361 ctacggttgt atctagtgtt tcttgtgtga ctccttgagc ttttagactc atgttgatgc
    12421 cgacagattt tcctaattca taaacagccg ttgctaaagc ttcgactaat tcctctgttg
    12481 tttcgccttt cagacctaag aattttgcaa tatctgcgta atctgtatct gcacggaaat
    12541 agtcatattt agggaacatc gcatgttttt gtggatcttt tgcattatag cggataatat
    12601 gcggtaaaag aatcgcattt gtccgtccat gagggatccc gtattccccg ccgattttat
    12661 gtgcgactga gtgacaaata cctaggaatg cgttagcaaa cgccatacca gccattgtag
    12721 aagcgttgtg cattttttca cgtgattcca tatcaggtgt ttttactgat ttttctaaat
    12781 agtcaaagac taacttgatt gcttgtaggc tcaatccacg tgtataatct gaagccatga
    12841 ctgaaacata ggattcgatt gcatgtgtta acacatccat cccggtatct gctgtgacag
    12901 atgctggaac tgacatgacg aattgaggat cgacgattgc gacatctggc gtcaatgcat
    12961 aatctgctaa cggatatttc acatgtgttt cactgtcagt gatgaccgca aatggcgtta
    13021 cttcagaacc agtccctgat gttgtcggga tacatacgaa ttgtgttttt tctggtttgt
    13081 cgatcttata tgtccgttta cggatatcca agaatttttg ttttgcacca aagaaagatg
    13141 tgtctgggtg ttcatagaac atccacattc ccttagctgc gtccattgca gaaccgcctc
    13201 caagagcgat tactgtatct ggcttgaagt ctgccatcag tttcgttcct gcgtatacgg
    13261 tatttgtcga tgggttcggt tcaacatctg agaagacttc gatcttcaca tcatttttac
    13321 gtcgtgccaa tacttcacga actgtatcgc agtaaccgaa ttggaccata ccagggtcac
    13381 aaacgatcat gacacgttca acgttttcca ttttctctaa gtacaataga gagttctttt
    13441 caaagaagat ttttggcggt aatttgaacc attgcatgtt atttctccgt ttcgctacag
    13501 ttttgacatt gattaagttt acagcagaga cgttacgaga aacagagttc ttaccataag
    13561 aaccgcatcc caaagtcaat gacggaatca tttcgttata gatatcaccg atgccgcctt
    13621 ctgcagatgg tgtattcact aaaatacgac aagctttcat tcgaagaccg aatttgacat
    13681 gcaactcttc gttttctgaa tggataactg ctgtatgtcc taatcctcca agattcaaca
    13741 taccttcaca caaatcaaac gcatggtccg tgttgttagc tttgatcatg gcaagaactg
    13801 gagaaagttt ttctcttgat agcggataat ctgggcctac gccttccaat tcagcaatca
    13861 gcattttcgt tccttttggt acactgattc ctgccaattt tgcgatttcc atcgcagaat
    13921 gtccaacgat tgatggattg accgcatatt ttccttcgtt catcactgca tcttctaatt
    13981 tttgcaattc atctggtttt acgatataaa cttggtgtgc ttggaattct gcttttactg
    14041 ctgcatagat ttctttatcc acgatcacag cttgttcaga agcacaaatc attccattat
    14101 caaatgtttt cgaaacgatc aaatcgttca ctgcacgttt aatttttgct gttttttcaa
    14161 tataagctgg tacgttacct ggacctacac ctaaagctgg ttttcctgta gagtaagcag
    14221 acttgaccat tccagctcca cctgtcgcta agacgatcgc aatacctgga tggttcatta
    14281 gcatagaagt cgcttcgatc gaaggatgtt cgatccattg gatacaattt tcaggagctc
    14341 cggcagcgat agcagcatca cgtactactc gtgctgcttc tgcagaagat ttttgggcac
    14401 ttggatgaaa agcaaaaacg attggatttc ttgttttcaa cgcgatcatt gatttgaaaa
    14461 tcgttgtgga agtcggattc gttgttggag ttactccgca aaccacaccg actggttcag
    14521 caatttcaat caatcctttt tggacatctt cattgattac accaactgtt ttatcatgtt
    14581 tgatattatg ccaaatatat tcggacgcat acatattttt gattgcttta tcttcgtaaa
    14641 caccgcggcc tgtttcctct acagccatct tcgctaatgg catatgttga tctaaagctg
    14701 ccattgccat ttcatgcacg atatggtcca ctttttcttg atcaaagctt tccatttctt
    14761 tcaatgctgc atttgctttt tctgccaaat catcaatcat tgcttgtacg tcaattgtct
    14821 tcgttttttc tttttccatt actttagcca tcattatcct cctaatgggt catggttatt
    14881 tgttaaatca ttcacatgta tatcatacaa tatttgtttt tctatgtaaa cacttttttg
    14941 tgattttttt cacag
//
LOCUS       DADVXB010000064        14945 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.065, whole genome shotgun sequence.
ACCESSION   DADVXB010000064 DADVXB010000000
VERSION     DADVXB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.065"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            159..335
                     /locus_tag="KB902_001562"
                     /pseudo
     CDS             159..335
                     /locus_tag="KB902_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(511..1080)
                     /locus_tag="KB902_001563"
     CDS             complement(511..1080)
                     /locus_tag="KB902_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6808394.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1154..2443)
                     /locus_tag="KB902_001564"
     CDS             complement(1154..2443)
                     /locus_tag="KB902_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808395.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2797..3645
                     /locus_tag="KB902_001565"
     CDS             2797..3645
                     /locus_tag="KB902_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBB6808396.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            3790..4731
                     /locus_tag="KB902_001566"
     CDS             3790..4731
                     /locus_tag="KB902_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBB6808397.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            4721..6892
                     /locus_tag="KB902_001567"
                     /pseudo
     CDS             4721..6892
                     /locus_tag="KB902_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7004..9175)
                     /gene="copB"
                     /locus_tag="KB902_001568"
     CDS             complement(7004..9175)
                     /gene="copB"
                     /locus_tag="KB902_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBB6808398.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9195..11381)
                     /locus_tag="KB902_001569"
     CDS             complement(9195..11381)
                     /locus_tag="KB902_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBB6808399.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11381..11590)
                     /gene="copZ"
                     /locus_tag="KB902_001570"
     CDS             complement(11381..11590)
                     /gene="copZ"
                     /locus_tag="KB902_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBB6808400.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11603..12043)
                     /locus_tag="KB902_001571"
     CDS             complement(11603..12043)
                     /locus_tag="KB902_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBB6808401.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12117..12656)
                     /locus_tag="KB902_001572"
     CDS             complement(12117..12656)
                     /locus_tag="KB902_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBB6808402.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13271..14737)
                     /locus_tag="KB902_001573"
     CDS             complement(13271..14737)
                     /locus_tag="KB902_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6808403.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4259 a         3128 c         2641 g         4917 t
ORIGIN      
        1 gccaattcaa cgtatacttt atagttcttt tcaaaagttt ctttatcatg tgtgtgttgt
       61 aactcgattt gcacaggact tttggctcac gaggttgtcc tactctacat cttgctgata
      121 gatatgctga aaggaaaaca ccaacattat gttttgcttt ttcagctaga acgagacaag
      181 caggaatacc tttagaagat atcaaagatt ttttaggtca taaagatgtt tccactacac
      241 aagtctatgc ccatatttct cccgaagtga aaaaaagatc aatgaatcaa ctagaaaact
      301 atatagaaga gcaaataaaa aagcactcaa attgagtgct tttttaagct cactatcact
      361 aaaactatca ctaattttat ttataagcga acatgtttct atcactgatt ttttaaatct
      421 agcgaaaaac ccttatctta aaggcgttcg ttcaattctt tggcaaggtc ttcaaagcct
      481 ggcttgccta gaagtgcgaa catggttttc ttatagctca tgtagaaaaa ttttcttgat
      541 gatgatttta tccatcaatt gagattgact gttttgctct cctatgattt cagctatgat
      601 tgtccgattt tgcggttttc ttcttaactg gtagttgatt ttcccagttt ccatcaactc
      661 gctaagcata tccacgactc cgccaaatcc ggtctttttc gtaataaaac ctagtgctac
      721 cattcgttca tctagatttt ttgctgtaat cgtcacacca gtaatgagcg agtgctgtaa
      781 tgtttgggcc agctcttcca tcccttcagc attggatacg acggaagctg ttttgttaat
      841 aggttcttcg tttatttctt ttggttcttt cctctccact ttcactgttt gacgaaggac
      901 atctagttct tgcaagagcg ttttgtattg ttcttgggtc agcatcacgc cagctacttt
      961 ttcacgatta aatatatata cgccagttcc cgcgtctcgc gcttgagcaa atacatccat
     1021 cggcgatcgt ttcacttctg tgatcgaaga tgtgggaact tctaatttct ttaattccaa
     1081 tggatttcct cctttactaa tcgcttttta ttatagcaca gactgacttg ttttgatctt
     1141 ttttccaaag gttttatcgg tttttgccta accagtaatt gatatcggta agaagtcttt
     1201 cgataccaaa tgaaggatgg tacagatacg ttttttgatc ttcgttatgg tctagtggaa
     1261 aaaaatgatc ggtgatcact agatctgcat accgaggcgg cttatttcga gtacatacat
     1321 gtatagagat ccgttttcga tgtcttagcg ttttgttcag taccccagca agtcttcttg
     1381 cttcttggtg ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg tggacatcta
     1441 aataccctcg ttcctggagt gttttcagta aaagcatccc ccactctact gcggggtgtg
     1501 caagtgcttg ttggatcgct agccgaaatt gatatagttt atctttggaa ttgggaaatt
     1561 tttctaatgt ttcctgataa taacgaactt cttctatcag ccggtcatgg ataccaatta
     1621 cgtaacgaag ccattcttgg taaagtactt ttatcagctt tgatttgctt tcgctctcaa
     1681 attcgctatt cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc aatttccgat
     1741 agtcttgtgt ctcttctatc cgtttccacc gcttttcagt aatctggtta cagctcaagc
     1801 gcaaaattgc tagataattt ttttctttta ttggcaaaat ctgctcctct ctaaatagca
     1861 attcaggaaa caattcaaag aatagtgttc gactgtctcc taaaatctcg atttctgccg
     1921 gatcctttct ttgcttcaat aattggatga acatctcaga aaaggactgc tctccatcat
     1981 ctgcaaaaaa atgcggaaaa tctttcaaaa agtaaaacag cagatatctt acttttcttt
     2041 ctgaaccaaa gatctgtgct tttttataag aaaaagaaag gtggtactcg ccaaaccact
     2101 ttctcaatcg ctcttgcgta gaacgatcgt acttctgctc gtaaggttca tttaatagca
     2161 gatttttcag taaacaaaac gggggtgatt ggatcagaaa aacaaacaag agataaggtt
     2221 cgctatatcc ttgatcataa actaactgaa cggttttctt atgaagaatc agctgaatgg
     2281 gacagtcgct ttccgccaaa cgtttcagat gccgatccac tgttttaaca tcgattttca
     2341 gttcttcagc taaatcagct tttcgccaga tcaaatcttt cattagattg attagtgaaa
     2401 ataaattctg tgcatttttt gataatagtt tttgccatct catcgatcat ttctcacctg
     2461 atttctaaac atattgtttg atcaaaatga gttcactcct aaaaagataa aaaactccct
     2521 ttctatttat ttaaatacgc aaatcttcct cattattttt tattttactc aatttaatcg
     2581 tattctcatt tcaaaacgaa tgtactttaa aaaaacataa taagatcact ttgcttgtag
     2641 gatgtattcc cttccattac aatgaaataa atagcgattt tatgagaagg tgatgtgaaa
     2701 atggaagaaa aaatagaaga atccaaacaa aaaatcgatc agttgatata agaattagaa
     2761 aaagcggtca tcggcaaacg ttcaactatc caattgatga tcgtggccct attagcaggt
     2821 ggtcatgtct tattcgaaga tattcccggt gtaggtaaaa cgttactggt caaagcacta
     2881 gcaaaagctg tacagggaac cttcagcaga gtccaatgta ctcctgatct gctgcctagt
     2941 gatattcttg gtttttccgt atacaattca caatcaaaag agtttgaatt tcgtccggga
     3001 ccgatcttta ccacgatctt gttggcagat gagatcaatc gtacgactcc tcgtactcag
     3061 tcagcacttt tagaagcaat ggccgagaat catgcaacga tcgacaacaa tacataccct
     3121 ctagacaatc atttttttgt cttagctacg caaaatccaa tcgagtacga aggaacatat
     3181 cctttgccgg aagcacagct cgatcgtttt ttattccgac tacaaatcgg ttatccttct
     3241 tttgatgacg aacttttgct acttttggat aaattcgaaa aagtgttgga taacttaaat
     3301 gaagtattga acagttatga aatagaagaa ataaaaacaa atgtggcgaa tgtctttgtc
     3361 agtcccgaag tggcatctta tgccttgcag ttagtgtcag caacaagaag tcatgctgcc
     3421 atccagcttg gcatcagtcc acgaggaagc ctttccttta ttcaggcagc aaaagcttat
     3481 gctttaatcc atgggagaaa ttacgtcacg cccaaagatt tgcaggattt agttccttac
     3541 gtgttttccc atcgcctgat tttttacgat cgttcattga aggaagacga aaagaaacaa
     3601 atcattcata ctcttgttgc acaaattcct attcctgtga ggtagattga ggtagacaat
     3661 ggaaaaaatc aaagattatt tcattaattt tgtgttattt ctggtatatt tcatcattgt
     3721 gctttttgct cttgtattca acaattcttt aggctggttc ttgttggcct tttttactct
     3781 ttatgtatca tggagcttga tttcattaag cagctttcta aagaaacttt cggttacttg
     3841 tacattgcag ccactcgttt atcgcaaaaa aagtatgcag gttatttttt ccatagcaaa
     3901 aaagagaact ttttctttac ctctccctcg tttacaaatc ggcttcccag caatctttgc
     3961 agaaaaaaac aagagatttt gattcttaca aataaaccgc aagaagtcca attgctttgg
     4021 cagccaaaag aaagaggatg ccatgaaaca ttaactgtca tttttacagc ctatgatagt
     4081 ctaggacttt tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac tgttctgcct
     4141 gctttttgta agattcaagc agaaaaatta cagagagttc tggaaaaaaa acagcagctg
     4201 aacgcgtacc aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc aggtgattct
     4261 ttcaaccgaa tcgattggaa attgtctgct catactcaag agtggttata ccgtgaatac
     4321 gattatcaag aagaagaatg ttctcctctt ttttgctttt ggggttcgcc cagtccaaaa
     4381 tttgaacctc tgctagactt gtatttttct ttatggcatt tgagaaaaga aaagcagccg
     4441 gaacttctga tattaggcaa ccgcgccttt catggcaaag accccggtca tacctatttt
     4501 gcttctttgg aagctggcga tgagaaagct tttttcgcac acttgaaaaa atatgcaaaa
     4561 aaacaaatcg tcctctttgt tcctgagaat tctcctgaag tctcagaagc tattgaaaca
     4621 ttgtcaaaag atcgaacggc ttatcttgtt tatttcgtag aaaaacaact catggtccaa
     4681 gaaaaagaca agatatgttc attgccagga ggtgaatgga ttgacgatta aacgggaaaa
     4741 atggctgcgt ggcgtttact cctttgtgat actaagtgta ggtgctccga tatttgtagt
     4801 agctaatcaa ttgcaaaaca gctaccttct tatcctaact attggtgtcc tatgccttat
     4861 tgtctgctgt attcctaaaa aatgggtacg tttgctgctt tctttgccag taatgatagg
     4921 ttgtttgttt ttatattttc cttcgaagac attttccata ttatggatct tacagttttt
     4981 ttcgtcagtt acagaggaat tcttccatct atcccaaggt aaactttatt atttgccaga
     5041 aaagacagct ttttttctca taatgttgct gatctattta tttattacat tgaccgtgga
     5101 ttacgactat tggtacgcac cctttctttc tttgatggct tacttcatga tgcttaccgt
     5161 ttttcggaaa aaagatttac tgtacgaaat gattgcggta gtaactgttt tgttcgtgta
     5221 tctggcagca aggcaatttt tctccatccg gttgttgtcg ggaaacactc gattccagtc
     5281 attgactaca gttctgctta tttgtttctt aacttttagc gctatcttgc ctttatatct
     5341 tccgaaagta caccaatctc tcgaggaaac gagtgaaccg atccgagaat atcttaatga
     5401 tgaagggctt tatgacacac tccatgagta tcaattaacc ggaagtgcaa gaacaggctt
     5461 cagtgagaat gatgaacagc ttggtggacc tttatatgat aatggcgaag ttgtttttac
     5521 agcgaaccaa aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt acaccggttc
     5581 tggatggata gaagatcagg acgcacccat ccaaccaatc caagaattcc ctgttgacat
     5641 cacgagctac caaaccgtta tagaagacaa agaaaacatt acattgaccc taaaaaaaca
     5701 agctttctta ccttatcctt atggaaatac taccttgact gatttttcat tagctagtgg
     5761 acaaacgctt tactatttgc ctgaaagcca gcgattcatt cctgtcccga atgaatcgac
     5821 acgttctgca actttacaaa cagaaaggtt agtttttacg agagaagaat taaaaagcag
     5881 tcagttaaaa gctgatgatt tagaaaatca gcagacaaat cttcaattgc caaaaagttt
     5941 gcctaaacgt attgaggact tggcggtcga attgaccaaa aatgaagcaa ctttaattcg
     6001 taaagtcgaa gctgtctaac agtatttaaa aacaagcgga aatttccgct attccaaaac
     6061 ggataccggg catactccga aagaacacga ttatgtggat tatttcctct ttgattcaaa
     6121 agtcggctat tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa cacttggtat
     6181 cccagctcgc tggacaaaag gttttacaaa tgggctcaga acaggcacag ataatcaagg
     6241 gaatgaggaa tacagcattc tcaatagtca tgctcattct tggccagagg tatactttcc
     6301 tggatttggc tggcttccat ttgaaccaac cccttcattt gccaatccaa tgggttcaca
     6361 accagttgct gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa atgaaagcga
     6421 aaatatggca gaaactattt ccagtgagag atctgaggtc attccatcag aagaaacaac
     6481 actcacacca gcttataaaa tcgtcttatt cagccttgga gtgtgtttat ccgtcttgtt
     6541 gttctttcta ttgttattca gaaaatctct gcgctggaca agttatctta tctatcttca
     6601 tttttttgct tctactaata cgattgcata tcaaaaactt cttaaccctt tggaaacatt
     6661 ggtaccgcgc aaacccgcag aatctttgca ggaatatagc ctgcgaatag aacaagaatt
     6721 caagctagat ctgcgtttca ttcgattaac tactcaatat gaagcagaaa tatatggacg
     6781 acaagcagat ccggtaaaat tcgataaaaa aacctattta gaaataacgc gtataataag
     6841 aaaaacggta tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat aagataaaat
     6901 ttctggagaa tctacttctg gaatgccgag aaccagctga ttgagtatcg attactcgaa
     6961 aaaaaggttg tgacacgttt tttgtcacaa ccttttttca ttattatttg attttcaatg
     7021 tcaaagcatt tagagctaca actaccgtac ttaacgacat caagacagca ccaactgctg
     7081 gacttaatat gataccaatt ggcgcaagaa ttccggctgc tagcggaatt gcaagaatat
     7141 tgtaacctgc cccccaccag aggttctgga tcattttctt tcgcgtttgc ttggctagat
     7201 caagaaaatg caaaatatct tttggatcgc tgtttgtcaa tacgacatcc gcagaatcga
     7261 ttgcgatatc tgtccctgca ccgattgcca tcccgattga agcacgggct aaacttggcg
     7321 catcattgat cccatcaccc accatgatta cttttttccc ttggtcaagg tatttctgga
     7381 caacagcttc tttatcatct ggtaataaac cgccataata ttcttcgatc cctaaataat
     7441 ctgctactgc ttgggcagcg tttttattgt caccagtaag catgacagga gtgatttttc
     7501 tttctttcaa tgttcggata aattcttttg cttctgtttt tactacgtca cctaaagcaa
     7561 cgattgcagc tagatgattt tctaaaatca ggaagctgat ggtatttcct tgttcttggt
     7621 aaggtttcaa taatgcttgt tctacgttta atccgagacg ctcaacttct ttttcattaa
     7681 ctattttcac ttgttgtttt ttgactgttg cctctagccc gactcctgaa agatttttta
     7741 gattttcagc ttgataaggc ttgatttcat gttctttcaa ataattcata atgccaacag
     7801 ccaatggatg attggcattc gcttccaagg ctcctagata ttgaaggatt tcatttttat
     7861 tgaacgcatc atcaagtact tcgacacccg ttacagtaaa ttttccttct gttagtgttc
     7921 ctgttttgtc cagcatgatc acatctagat cattggcttg ctccagtgca ttgcggtttt
     7981 tcaaaagtaa tccgttttta gctgctattg atgtggagcg agcaacaact aatgggatag
     8041 ctaaacctag agcatgagga caggcgatga taaagactgt taccatacgt tctaatgcat
     8101 taggaagatc tgtcaagaac aaccaggcga tgaatgccag gatacccaca attaatgcga
     8161 cataaaacag ccattttgcc actttgtcag ataatgactc tagcttggat ttttctcctt
     8221 gtgcttttcg caccatttcc ataaccttcg ctagataacc attttcacca gttccagtta
     8281 cttcgatttc gatcgttcca tccccattga tagaaccgcc aatcactttg tcattggctt
     8341 gttttttgat tcctcttgat tcgccagtca cagctgattc gtcaacaatt gtttcacctt
     8401 tcaagattac accatctgtt ggcattttat caccagaccg gacgatcaaa cgatcacctt
     8461 cgtttacttc tttcaatgaa actgtctctt cttttccatc tttcgtcaag cgtttcactg
     8521 attctggcag taattctgct agtttttgta aagcattgct ggcattcgac acagcattca
     8581 tttcaatcca gtgacctagt agcataataa cgatcaaagt agccaattcc cagaagaaat
     8641 ccatgacgtg tgtatgtgga ttgagcagat ttgcgataaa cgaatagaca ctataaatat
     8701 atgcaactgt aatccccatc gcgatcagtg tcatcatagc aggacttttt tgtttcaatt
     8761 ccatcttagc tccacttaaa aatggctgac cgccatagat aaatagtata gttgctaaga
     8821 tcaatacgag ccaatcagaa ccaggaaacg ttacttgaaa tggaaattcc attcccatca
     8881 ttggtgaaaa aagaatgatt gggatagcta ggataagcga tagccaaaat ttttgtttga
     8941 aattccccat gtgcatggaa tgatccatgc cgccgtgttc gtgatccatg tgcatcgaat
     9001 ggtccatttg tttgctgttt gctatatctc catggttatg tcccatgtgc atggaatgat
     9061 ccatctgact atggtcatgt ttcatctcca tctgtttttc atgagattct gtactttctt
     9121 tgtttactac ttctttttta tgctcatgtt ttttctccat atcgttccca ttcattttta
     9181 ctccatccct tctcttactt tttcatgtgt cgatttaagc tcagggagtt caacaataca
     9241 ctgacggaac taaacgccat cgctcctcct gcaatgattg gattcaaaaa gcctagtgcg
     9301 gcaaaaggaa taccaatcgt attatagaca aaagcccaga aaagattttg tttgattttt
     9361 ctcaatgtca acctagacaa ctcgattgtt tgtgcaatgg atgccaaact gctattcatc
     9421 agcgtcacat cggctgtttc catcgcaatg tccgttccac ttcccattgc cataccgaca
     9481 tcagctaatg ctaaggccgg tgcatcattg attccatcgc ctgccatacc gacttttttg
     9541 ccatctttct gaagtttttc tacgtaggct gctttatcct ctggaagtac ttcagcaaag
     9601 atatgctttg gatcaatacc aacttgttta ccaatcgttt cggctgccag tttgttgtct
     9661 cctgtcagca taaaaacatc taatccttta ttctggagct gcttgattgc ttgtttggct
     9721 tctagtttga tttgatcagc cacggcaatc cacccgatca cttgcttttc atcagctaaa
     9781 aacatgactg tttttccctg ctgttctaat tctaacgcgt gttcttggta ttcatcaaat
     9841 gataggttca attcaattaa tcgtttacgt gtacccgcaa aatagcgtac tccattaatc
     9901 gtaccgctga tcccagcacc tgggtgggct gtaaaatcaa tcatatcgta tgttgctgct
     9961 tcttgcagtt ttccgtattc cacgattgct ttacctagtg gatgttcaga agcttgttct
    10021 aaagtataaa aaatagatag gacttctttt gaaccgacta gatctgtaac tttgggcttt
    10081 ccttctgtaa tcgttccagt tttatccaaa acaatgctgt ctaagtgagc agctgcttct
    10141 aatgcttctc cgcctttaat taaaattcca tttcgtgcac caacacccgt tcctaccata
    10201 atagctgttg gggtcgctaa acctaatgca catggacacg caatgactaa tacagagaca
    10261 ctatggatca atgcgagttg ccaatcacca gtgatcaaac ctgtagctat gagcgtgata
    10321 aacgcgatga ctaatacgat cggaacaaaa atccctgaga tccgatctgc gattttttgg
    10381 attggggctt tgctcccttg agcatcttcc accatttgaa tgatttgcgc taatactgtc
    10441 tgcttgccga cttgtgtgac ttccatgtgt agcagaccat tcgtattgat tgtcccgcca
    10501 aaaagcgtgt catccggatt cttttctaca ggaagatttt caccagtaag catactttca
    10561 tctatcgcac tgcttcctga aataattcga ccatctgctg gaatctgctc accaggacgg
    10621 atgactagtt gatcaccaac gactacttct tcaatcgcta acgtttcttc tttcccgttt
    10681 cttatcactt gggcggtttt tgtttgaaga gacatcaatt gtttgattgc attacctgtt
    10741 ttcgtttttg ctgtatgttc caaatatttg ccgagcaaaa tcagcgtgat gatcatactg
    10801 ctgctttcaa aataaagatc ttgggggtgt ccacggaaaa atccgttgta aatgctcaat
    10861 gcaaaggcag ccgatgttcc aattgctacc aatacatcca tatttggtgc tttcgtcttg
    10921 attgcatggt acgcaccttt ataaaaacga gcaccgacat aaaattggac aggagcagac
    10981 agcactaact ggacgattgg aaaatgaaaa aagtgaacaa tcgccgcatg gcttcctaac
    11041 atcatagcaa tcattgacaa catcaacggc aaagtcaaaa ccgtactcaa tataagatcg
    11101 aatagcattt ttttcaaata cgcttgcttt tcttctgcaa ttttttgttt gtgggcttca
    11161 tcgtacaaaa ttgcaccata accgatgttt tctacgcttt ggattaattt ttcagtggtc
    11221 gtcccttcat atttgacact tgctttttca gtggccaagt tgactgtggc attgaccaca
    11281 ccaggttgtc cgttcagctc tttttcgatc ctagcagaac aatttgcaca agtcatacct
    11341 gtaatgacga acgtatccat tttggtttct gctgttgcca tcaaatcacc tctgctttat
    11401 aacccaatcc attgattgct tgacaaatct tttcggattg aacttttgtt tcatcaaact
    11461 tgaccgtacc gtttgctttt ttcaaattta ctttcacttt ttgcacgccg tcaagtgcgc
    11521 ttactgtttc ttctactctt gctgcacaat gattgcagct cataccttcg attgaaaatt
    11581 gttgtttcat tttttcttcc tcctattgat gttgtttaca ttcacattga cctgggatac
    11641 agttacattc gatcgtatct actggttgct tttgttccag ttgtttcaaa atctcattga
    11701 tatcttcttg agtcaaagtg gcttcttcta ctagatccgc aatcgtctct ccaatccttt
    11761 ttgcacagat atgggaaaaa agattttccg tcgcactgcg aactgtttcc atctccgaga
    11821 cagctggatg ataaatgaat ttttttcctt cttgttctgt ccagatcact tcttttttta
    11881 ccaaacgtcc cagcaaagtt ttgatcgttg ctggtttcca atccatcgaa tcagctaaga
    11941 tctgcgtgat ttcttgggct gtcgtctgtc caagtgtcca aataacacgc atgatctccc
    12001 actctgaatc actgatcttt actggcgttt tgactttttc catttatttc acacctttcg
    12061 tttacaaatg taatcattag cttatgaata cagattacgc ttgtaaacaa aaactgtcaa
    12121 ttatttttgc tctctatttt caatttagtt aaaaattctt gtttctctcg tcttgtttta
    12181 aggatgatca gtttatttct tgcattagct acttggatca gctgctgtat tttcggttca
    12241 ttgttttctt caaaatgcca gataaaagat aaaaattcta agtattccct gtttagtttc
    12301 tctgaaaatg attcaggcat atctggccga gattttttgt ttatctttct ttttagagaa
    12361 cgccaaacta ctcggtagat ggcgagataa cgcggcactt taagccaaat gatcttatct
    12421 gcttctttaa tcctttcctc taatgtagaa gtataatttc cttcaacaat ccatgacgga
    12481 ttagatacca taaacgattg ctgttcttgc aaaaaccact tttttgcctg aatactgtag
    12541 tctgttgtat gccataaaag gtctagcggc agtagcggaa agtcggtgat ttctttgatc
    12601 ttccttgcga gggtcgattt tcccgaccca ctttgtccaa tcacgatgat cttcattctt
    12661 ctccctcact tctctttgga atttggttcg atcataccac ttataacgcc gcaaaaaaac
    12721 aagggactgt gacaaaagtc gtgtcaaagt cccttgtttc gaataaatgg tgttcaatca
    12781 gctgaccttc agcattaact caaaaaacgg caaaatatga ggagctattt tttcgtttgt
    12841 tcctctaata ctcaggtcaa atcgctgatt ttacaacctc ttccttaaac ggtgttctcc
    12901 tgccaacacc tcggtcacaa ggcacaatag tcaacaaaca tgagaagttg ttttttgaaa
    12961 ttgctccttg tgactcggag ttaaacggca ggctcactac ctctttctta aacggtgttc
    13021 aaaagcttgc atctgcggta ataagcccag caaaacgaaa aatatgaggg gctatttttg
    13081 tttggctgtt cttattactt gatgcaggac agctttttca caacctctga ttcacggtgt
    13141 tccagaagta gcttctgcga aaaacaagcc gaaacttcac aaaaatttga gaagcaattt
    13201 tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc ttgtaacaag
    13261 tatttctatt ttaaggctga accactgttt ctggttcagt gatttctttg tttttgtctc
    13321 gacgagcaat tgctggcaag atcataccta ataagatcaa gacaattggt gtgatgatat
    13381 tcgtgaataa ttggaaccac catgctttag gatcagcagt ataatctact tttggcacca
    13441 ttcctaggat acatgcaaac gcagtgaagg caaagcacca agcaccaaag ataaaaccga
    13501 tttttggatt tttaacaaat ttatattcag aattgaattt cttataagct ttattcaaca
    13561 tcatatatgc caagaacacc cataggtaac gcattggcat gacaactgag ttcaagttcg
    13621 tcaaccattt tactaattca ttcatatctt tgataccaaa gatcggcaac aaaataatga
    13681 ttcctactag tatacctgtc agaagataac cattcaccaa tgtaccttta cgattacgtt
    13741 tacgtagcca gtttggtaca aattctggat ccgcatctgc taacaagatt tttagtggtg
    13801 catcaattga aaaggctaat gcggagattt gtccaatcat gtttgtcaat gcgtaaatga
    13861 tcatcaatga gttaccgata ccatagtaat tacctaaaat ttgaaaagca ctgtatgccc
    13921 catttgccat caagtcttta ggaatattat cgctagcaaa cagcataccc attgcgactg
    13981 agcctaatac agcacaaatc cctaccattg ctgctaagaa gatcatccct ttaggaaatt
    14041 cctttgcagg atttcttgta gagttgacat aaggggatat tttttccgct cctccaactg
    14101 caaatactag catcgaaacg gttgtgaaat aactgaaatc aaatgttgga atatatgttt
    14161 tcacttgatt catatgtggt gtggcaaatt ccatcgttgg attgatgaac ggtgccgtta
    14221 cagctaaaag aataaataag atcgacatga cgaacatcgc tgttccggcc agtccgccaa
    14281 tcactttcaa agtagaaagt ccttttgttg ataaatataa aaaggcaaga aatataataa
    14341 gtgaaataac tgctaccatt tgtactgaca tcgtatttac gatatttcca tttccttgga
    14401 ctgcccaacc gccagcaatc aggattgctt gaggcttttg tgccaaataa ggaatatgga
    14461 cgacccagta agtccaagcg gcatagtatg ccagtcgttt attagatgtc gtattttcga
    14521 cccatgaact gacgcctcct ttactatcct tgaaggctga ccctaattgt ccaacgatca
    14581 atgcgtatgg aataaaataa atggccaaaa tcaatagcca agaggtgaca actgatactc
    14641 cttgctgagc atagttatta actacattcc ccatgcccca aaccatgtta aatgcaatta
    14701 acgcaacagt aaaccagcgt aattgtttgt tgttcattcg ttctctcctt tatgataaaa
    14761 atttgttatc cagatgtaat catattcaat ttttaacaaa cttacaagac agtgttattt
    14821 tatgtgtgta ttcttttatt taatacacat cgttttttca tattttttcc atcaaaaaaa
    14881 taagttattt tcttttattt catttacctt attgaatttc aagctatttt gaattttctg
    14941 caaaa
//
LOCUS       DADVXB010000065        14838 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.066, whole genome shotgun sequence.
ACCESSION   DADVXB010000065 DADVXB010000000
VERSION     DADVXB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.066"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..418
                     /locus_tag="KB902_001574"
     CDS             <1..418
                     /locus_tag="KB902_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808404.1"
                     /translation="EKTEIISNSYLSVFINSNNKYACEYVLSFEREMRKMRAGVYFAT
                     QTPEEIIPKDSGSEVADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLL
                     PELEVGQAVVQTSSEDTYMINFDPYPEQIERFDGGQ"
     gene            440..1576
                     /locus_tag="KB902_001575"
     CDS             440..1576
                     /locus_tag="KB902_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6808405.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            1591..2241
                     /locus_tag="KB902_001576"
     CDS             1591..2241
                     /locus_tag="KB902_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6808406.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            2255..3151
                     /locus_tag="KB902_001577"
     CDS             2255..3151
                     /locus_tag="KB902_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808407.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            3187..3417
                     /locus_tag="KB902_001578"
     CDS             3187..3417
                     /locus_tag="KB902_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808408.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            3768..4064
                     /locus_tag="KB902_001579"
     CDS             3768..4064
                     /locus_tag="KB902_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808409.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            4061..4528
                     /locus_tag="KB902_001580"
     CDS             4061..4528
                     /locus_tag="KB902_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808410.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            4595..6130
                     /locus_tag="KB902_001581"
     CDS             4595..6130
                     /locus_tag="KB902_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808411.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            6152..6481
                     /locus_tag="KB902_001582"
     CDS             6152..6481
                     /locus_tag="KB902_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808412.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            6483..6746
                     /locus_tag="KB902_001583"
     CDS             6483..6746
                     /locus_tag="KB902_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808413.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            6921..7787
                     /locus_tag="KB902_001584"
     CDS             6921..7787
                     /locus_tag="KB902_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808414.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            7942..9768
                     /locus_tag="KB902_001585"
     CDS             7942..9768
                     /locus_tag="KB902_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6808415.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATNEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            9776..10849
                     /locus_tag="KB902_001586"
     CDS             9776..10849
                     /locus_tag="KB902_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808416.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            10858..11118
                     /locus_tag="KB902_001587"
     CDS             10858..11118
                     /locus_tag="KB902_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808417.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            11155..12159
                     /locus_tag="KB902_001588"
     CDS             11155..12159
                     /locus_tag="KB902_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6808418.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKAPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLHGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            12184..12540
                     /locus_tag="KB902_001589"
     CDS             12184..12540
                     /locus_tag="KB902_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808419.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            12702..12893
                     /locus_tag="KB902_001590"
     CDS             12702..12893
                     /locus_tag="KB902_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808420.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            13002..13220
                     /locus_tag="KB902_001591"
     CDS             13002..13220
                     /locus_tag="KB902_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808421.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            13257..13574
                     /locus_tag="KB902_001592"
     CDS             13257..13574
                     /locus_tag="KB902_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808422.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRFIEVNNLGIIEDYLDKLDEAIKQSIEKNGEDHILTVVLKDLKDRLEAEAEYF
                     NKD"
     gene            13585..13782
                     /locus_tag="KB902_001593"
     CDS             13585..13782
                     /locus_tag="KB902_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808423.1"
                     /translation="MRAMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            13779..14747
                     /locus_tag="KB902_001594"
     CDS             13779..14747
                     /locus_tag="KB902_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6808424.1"
                     /translation="MSLENEKPYYVVVGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIKGHFKEGKSFHHETTFGGNPYPDKMRLLKAKK
                     LGYESFLIYIGLDSPERAIERVKIRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
BASE COUNT         6026 a         1727 c         2842 g         4243 t
ORIGIN      
        1 ggaaaagacg gagataatat caaactctta cctatcagta tttatcaatt caaataacaa
       61 gtatgcttgt gaatatgtac taagttttga gcgagaaatg cgaaaaatgc gtgcaggtgt
      121 ttattttgca actcaaacgc ctgaagaaat tatccctaaa gattctggat cagaagtagc
      181 agatgtgatt agaaacattt ttaatctatg tacttttaaa tgcttcttta atttagattc
      241 tgcattgttg gaagacataa aaaaagtttt aggaaataca attactgata cagaaattat
      301 gcttttacca gaattagaag taggacaagc tgtagttcaa acttccagtg aagacaccta
      361 tatgattaat tttgatccat atccagagca aattgaacga ttcgatggtg gtcaataata
      421 gaaatcggag gtgaatttaa tggagcagaa caaaaataat aatgttgctt caacactcgc
      481 tcgtcaaggg atgaagcaag tatcaaagaa aataggtctt gctttaaaaa taaaaatagg
      541 ggtagttata ggactgataa cattggttgg ccttttagtt ataggttctt tagctacatt
      601 acaaggaaca caaactgcaa ctaatacagg aggtgcagaa gtcattggtg gcaacaaacc
      661 gttgtcacct gaagttcaaa aatggcaaaa aacggtagaa aaatatgctg aaaaatacgg
      721 aattaaagaa ttagtacctt atgctttagc aattatgcaa tgtgaatccg gaggtaaatt
      781 gccggattta atgcaaagta gcgaatcagc cggattgcct gtaaacacac ttcaatatga
      841 agaaagtatc gatcaagggc taaaacattt gagtaatgtg tataacattg ctaaaagtta
      901 tggcatggaa agtaactatg atggaatagt tcaagcttac aattacggaa tagcttacat
      961 gcactactta ggaaaaaaca aaaaaacaca tactatcgaa acggctgaag cctactctaa
     1021 aaatgttgtt gctccaagtt taggaaatac tacaggacag acttattcat atgtaaatga
     1081 agtatcaatt aaatatggaa aaacatattt gtatttaaat ggtggtaatt tttactatgc
     1141 agagttagtt aaacagtata tcggtggggg tagtggtaat ccggctaatc cttcagaatt
     1201 ttggggaaaa atgaaaacag aaatggaaaa atatcaaggt tggccttatg tttggggcgg
     1261 taaaaatcca acgacaggtt ttgattgtag cggattaaca gcttatcttt atcaatttag
     1321 cgccggaatt acaatagata gttatacagt aacgcagtat gaagcaactg aagcagtatc
     1381 aattaaagaa gcaaaagctg gtgatctgat tttctttaga ggaacatatg gagcgcctga
     1441 tttcatttct cacgtaggta tttatgtcaa tgaaacaact atgtatgaca gtaattcaag
     1501 cggaattggt tatcacaatt ggcaagattc atattggcaa tcacatagtc cagagattcg
     1561 tagagtcaaa aaataggagg aagaaaatag atgattaaga gaaaaaatga taataaatgg
     1621 aaatatattt gtggtgtttt aattattatt ttagttttag gtggattgtt atctcaactt
     1681 catacaagta acattcaagc aaaaaataaa aaattggatc aagaagttac acaactagaa
     1741 gaacaaaata gcaagttaag taaaaatatt agtgatctaa atgcaaatgt agaagcgaac
     1801 ttaactaatg atgatggcag tgaattaaat aaacaaattg ctgaagttgc taagaaattt
     1861 gttgagctat atccggtata tgatattgaa aaagtagaag aaaagaaagc tgatttagag
     1921 aaaatagcta ctccttctgt agctgattct atcgtgccgg acgacatgat tacaacgagt
     1981 aaaaagactt tagaaagtaa atctactact caaaaaggag aagcatattc aagtgatcca
     2041 acattcaaaa gtaaatataa agattcaaaa ttatatacga attatgttaa cgccaatact
     2101 attaattatt ttgctgaagt aaattataaa acagaatctt ctagtggaga tacagaaaat
     2161 acagtctata tgctttttga agtaaccaat aaagacggcc aagtgttggt agataattat
     2221 gaaatcaagt acttaaaata gtgaggtgaa gtatatgaat aagaaatatt ccattcataa
     2281 taagaaggaa ccaaataaaa aaaataaggc acaaattgac aaagtatata aaaaaacgaa
     2341 aggagtaaaa ttatatttag gtgctatact tggattttta gcaataggaa tgataatcgt
     2401 tttttctcct tatgtgatgg ggaaaagtta tgattttgaa actgtaaaaa tgagttcagc
     2461 ccaaaatgta acgtcttctt tgaatatgta tgttgatgat atggaaataa atagggaagc
     2521 cggactgttt aaattagtat tgcggtatca agatgataca ggtactaaat cactaagtaa
     2581 tattaaaagt gactataaat taaattttat aacgaacaaa aataatgaag atgttaagac
     2641 aaaagttgta aaattgtcag atgaatacac ggtaatttat tatcaaaatc tgcctaaaga
     2701 ttttggtgta atttctgtga cagttaaccc tagatatatt tatcctgaat tagaaccttc
     2761 aaatgactta aaagaaaagg aaataaaatt ctatgcagta gacaaagata ttaaatcaaa
     2821 tgctaaattg gaagttgaaa gtacttctga tttgcaaaaa gataatttta aatatcagat
     2881 taaagctata gaaaattcta taaaagatga gaaaaaatca attgaaaaaa tgaatttagc
     2941 aaataaagta gtgcaaaaag atattgataa agctaatcaa aacttagaat ttcaaaccct
     3001 agacgaacaa acagatacaa aaaatgaaat cagttctatg cagacgacta ttgaaaataa
     3061 taaatcttca atagaggaaa gtgaaaataa aatcaaacaa tttgaggaaa aaataaagca
     3121 actagaaaag tctgcaagcc gatttgagtg atcgtgttta aattatttta agggagttta
     3181 gagagaatgt gtaattctat tgtcactatt caagagaaag ctgaagaaga attaatgaga
     3241 attgaagcgg aatataaaga aaagagaaaa gcgattaagc gcaaaaaaaa tgcagagctt
     3301 aaaaaatata aagaggaaca agcgttaaaa ttaggaatga tgttgtgtaa atattatgat
     3361 tgctatgata taaacgaagt gctaaaaaaa gcgaatttaa accaattttg tgaatagaaa
     3421 agagagtggc aaggtaaaac ttgccactct ttttttgggc gtaaaagctt tagttactat
     3481 gaccaaaact acggacgaaa ctatgaccaa aagtaggtac tatattatga ccgaaaatag
     3541 gtcgaaaatg gatttttttg tgatagcaaa aaatatgaag ctattttgaa agaaaaccag
     3601 ttggcacagc caacttagcc accttccttt aggaaggtgc tatcagtttt cccttatgct
     3661 ctttgtatta attccttggt cttgtcttta aatctttaat tttcctttgg actttgatat
     3721 aataatatat accagataga taaaaacagc ttgaaagagg tgtgtgtatg gatgtttcaa
     3781 tcagaggaat tgatccacaa tatgtaaaag agattgataa aaaagttaat aaaattcaag
     3841 aacgtaccgg aaaaaagttt agtaggaatg actatttttt agcaatcatt cgccaagata
     3901 gcgagatcga tttgattgac tataaaaagt cagaatttga tttagtagtt gaaaaacttt
     3961 tattgtcaaa tgaacaaatg gtagaaagta ttagcgagtt aacttcagtt tatgaacgct
     4021 tattcaattt tttaattagc gaaaggagtg atttaaataa atgaactacc cttatttcaa
     4081 agtatcagca acagaagatg taaaagaaaa attcaataag tgctttgaag taaacaagtc
     4141 agtatttcaa acaaaatcca atatgttccg ttatgttgtt tcaaatttac caatgttaac
     4201 aaaagccaat caaaatttcc gtgatccaga aaaagaagag ttagctaaaa acttagaaga
     4261 agcaaaatta aaaattagcg aacttgaaac gataatagaa ttgcaaaaac agcaacttga
     4321 aaactttaat aaaaaagaag acagtacaca taaagattat agtgaacaat taaatagtat
     4381 agaagagtct gtctataaac tattaattaa tagtggatta gctagtaaag aattagaaga
     4441 agagcgtgct gaaccagaac aagaaagtag tcgtttggga gagggaacaa tgtttagttc
     4501 accgtcatta agatttacaa cggattgaac actaaaaaat tctaatgcaa cttagcatta
     4561 agtacaaaac cgcctgtaga aaaaattttt gaaaatggtg ggtgatgata tgactgaaca
     4621 tatctttaac agaaaaagtg cgagcattat tcttaaagca aaatttgaaa ctggaaaaag
     4681 caaaaagaat aatcacatgg tagaacttca aaaatttgta gattatattt ccagacaaga
     4741 ggctattagg caagataaac tagatcatga ttattcagaa gatgaactaa atgaattagc
     4801 tagaatagaa aaagctttgg aaaaaataga acaggaaaca gatcaaccag tgattaaaga
     4861 tttacgtgaa atggataaat atattgatta tatgacacgt aaaaaagcta tcttagaaaa
     4921 tgtagataat gaaatagtaa acggagcatt tagcaataca aaaagatata tcactaaaaa
     4981 agacatttca aaaataaaag aatcggtcat agaagcaaaa aataatggat cggtgatgtt
     5041 ccaagatgta atttcattcg ataatgattt tttagtaagg gaaggatatt ataatccaga
     5101 aacaaatgaa ttaaatgaaa atgttctata tgaagcaaca aagtctatga tgggaaaaat
     5161 gcaagaaaag gaagaactag ttgatccttt ttggtttgca acgattcaca gaaatactga
     5221 acatatccat attcatgtaa cagctatgga gcgtaaaaat actcgtgaaa taatggaata
     5281 tgatggtgtt ttacaagcta ggggtaagag aaaacagtct acgttagacg atatgatttt
     5341 taaattcggt agcaaaatat tagatagaac gaacgagttt gaaaaaattt ctaagttgag
     5401 aaaagaagtt cctttagaac ttaaacagtc tgtaaaagat tctttgattc aattatatgt
     5461 agaaaataat tcaagatatg acaaagaatt agtaaagtac ctaaaggaat taaaaaaaga
     5521 aatacctagt acaacacgtg gctacaatga gcttcctgaa gaaacaaaag aaaagattga
     5581 tgaagtcaca aattatatga caaaggataa tccaaaaaga aaagaatatg atcgtatgac
     5641 taaagaaatt gatgagctat atcaaacaac ctacggtaaa cgctacaatc cacaagaata
     5701 ttatttaaat agaaaaaaag attttaatgc tcgaatgggt aatgctgtag taggacaaat
     5761 caaactttta aagcaatctg aagaaaaaaa tttgaaaagt aatgaactta aaaatctatt
     5821 agacggaaaa aaattaaacg ttaagtttga tagagaaaaa ccagaattta aaacgaaata
     5881 tgctaaacaa agttatgatg atttccaaaa aagattagaa gaacgacaat tagcacgtga
     5941 aaaaaatgaa gtccacttca agaagatttc tgaaaaattt aaagataaaa agcttattag
     6001 aaaaattgat agagtaatca atgatgattt aaatatgtat cgtgcgaaaa atgattatga
     6061 agtagcgcaa cgaatgatag agcaagagaa aatgagacaa gcacgtgaat ttgaaatagg
     6121 aatgaattag tagaaacgga gaatagaaat tatgaaaaac ttcgatatag tgtgcagtaa
     6181 tacaaaaaat atatatttac gtgagctact taacagtgat tcggaaacta tagaagatgt
     6241 aaaaaaaatc atagtgttgt ttgaaaaaga aaacatggag ctagagaatt gggggctttt
     6301 tgaaataccg attagtggga attactgttt ttataattgg aagacagaag acgatgtagc
     6361 ttttgcaaat tacttttttg ataaaaatta cttttcccca ttatatatag ataagcatag
     6421 taatgaacaa gttgcttctt caataaaaga agcaataaaa ttggaaagag tgaggaaatg
     6481 atatgatcga ttttagaacg gttatggata aactaagtaa tggagatttt cgcgtattga
     6541 ttgaactata cttaaatgta acgtctacag tcaaagagtt tttatattct aatcccaaaa
     6601 cagctttagt attagttgca gtactgatag tttttgctgt gatctctttt attaagaaaa
     6661 tgattccgct attaattata ggtgctgtgt tgatattagg tttgtatttc cctgaagttt
     6721 tggatcaaat aaaaaatata ttttaggctc taaaagcttc cagtagaaaa ttttgggctt
     6781 tgatatttgt attaagcggt ttgaaataga aatttgataa actacatgaa aagacattat
     6841 ataagagtat ctgtgtattg gaataaaaat atgataatat aaaattatat atcagaccga
     6901 taaaaaagag gtgcttataa atgaaaaagt taagagttat tgcaacaata cctatgattt
     6961 ttagttttgc gctattatta tctgcatgtg gcaaagaaga agctggtgct aagtcaaatg
     7021 aagcacataa tatctcattc atagatagtg cagaacaaaa agactcacgt tgttggttgg
     7081 tagtcgaaac aagtagtaaa aataaaacgc ctattgataa aaatgaatat gtaaaagcgg
     7141 tgatccaaac taaagatggc aaagcaaaag tatttaaaac ggatatggaa cagcttacat
     7201 tggaaaaagt ttctaaaatg agtgatgaag aaataataga acaagcattg aacgctgata
     7261 aacaaaagtt taatgataag aaaaaaagcg atattgatag ctataatgcc actttagatt
     7321 ctgtaaaaac agaattagaa aatgaggaaa aacaagagtt tcaaaatgac caaaaaattg
     7381 ctgattttca agatagtata cctaaaatac aggcggatat agaagagatc gatggtgttc
     7441 aatattcaga gccggagtgg aaaatggtat cagcaacaat taaaatggat aatgaaaaca
     7501 aatcaccttc aatggaaacc gttaaattat cttataaata tttagatagt ccaatttgga
     7561 atttaaatag ttttggtgaa gtttcgtctg aaggagaatt atcttatgaa tctactagta
     7621 tggatttgaa gttatcaatt ccagttgcca caacgaaagt tttagataat ttttattcag
     7681 gatattctaa tgatgaattg gatcaacttt tgcttactaa agtagcttct aaagataaca
     7741 aagttcaatt agatagtaaa ggtaaaaacg taagtatagt tgagtagatg gtaaaataag
     7801 aagggataag atggttacta taactatctt atctcttttt tatttgcatt aagtcagtga
     7861 aattagatag aagagttttt atatatctgg tataatttaa ttaggtaatt taacttacct
     7921 aaaaaagaaa ggagatagaa gatggcctat aaaaaaggaa actggaagcc gaaaacgaaa
     7981 gagcaaaaac aaaaagagct agacgattta attaaggctt ccaacagcaa aatcgagcaa
     8041 tatcagtcta accctgaaga tatgatcgag tttgccaagt tcatgtctaa aatacacaat
     8101 tacagtcctt taaacctatc gttgatcgat gagggatttg aaggagcaat tgctgtagca
     8161 agttatgatg gttggaaaaa actaggattt caagttaaag cgaaagaaaa agggataggc
     8221 atttatgcgc atgctccggt aacggttttt attgatgaaa atggtgagga aaagacgtta
     8281 aaagaagcga caaacgagca aaaagaaaaa atcaaaaatg gagaattaag aagcaaaaag
     8341 atcaagcatt ttaagaaggg ttacgtattt gatatttccc aaactaatgc aactgaagct
     8401 gatttgccaa aaatatttcc taacagggta tggaatttta atattgatgg tgaattaagt
     8461 gttagtcaat tagaaaaagg tgtaaatcat ttggccgaat ctatgaatat atctataaaa
     8521 gatatgaacg agtctggtag aggtgaaatg ggaagcgcta gaggtgaata tattcaatat
     8581 gttgatggta gggaagaaat tgtattaaat tcaagaaata gcagaacaca aaatcttact
     8641 accagtattc acgaattggc tcacaaaaag cttcacaata agaatgaaca cggttcttcc
     8701 tactcaacac cgattaaaga gtttcaagcg gaaatgactt catttattgt ttgtcacaat
     8761 tacggtattg atacgtcaga ctttactatt ccttatattg caaattggac taaaaataat
     8821 gaaaaaattg atccaaaaaa ctttagacag ataatgcaag aagttagaga aacgtctatt
     8881 gactttataa gtacgattga taagaaagtc ttggaagaac agcaaacagc atttaatgca
     8941 ctaaaaaatt cctttgttcc taatgagaat aaagagcaga tacaacaaaa atcagattta
     9001 gaatttcata atttctacga tagtacaatc aacgatccgg atagaacaat ccacggtagt
     9061 tatttagaag cgatggtgga ttattataga ggaaagtatg gagaaaattc tattgagctt
     9121 actcatagca attatgatgt tacagctaaa ataggagaaa actatgtgac atattattca
     9181 gatacgaaac aatttgatgt atgtgatgtt tatggtgtag tttttgagaa tccaagtgaa
     9241 aataaacatg atcgtttact attagatcga tcacctgaaa attgtgatta tgttgaaaag
     9301 tttgttgtag aaagtttgaa agcttgcgag aatcatgaac taaaaaatga tacgttaaaa
     9361 ttaagcgaac cgctaagatc agttgttata aatgaagcgg tttataatct atctgaaaat
     9421 gctaacaatt actataatga aaaatgctgg caagaagaaa ttgaaaacca aacaaatatt
     9481 aatgatgtaa aagaattaaa ctcttgtatg actgcggaag atttttacga atctcataaa
     9541 caagaaatcg aaaatacgat tacagatttt gaatctgtgt caggaacaaa tttaagagat
     9601 acaatagaca atgagtcata taaagaggtg gcttcagtgg tagcttataa actggttgca
     9661 actaaagtaa aatatgaaat ggatgaagga actttcaaga taccagaaaa ttctaacttg
     9721 gaaaagccga ctgtaaaaac agcagaacgt tcttttgaaa tggagtgaaa aaattatgag
     9781 taatgaacaa aattatgaaa caggcggaac ttatcgcctg tttcatggaa gtatgaataa
     9841 atttgatgaa tttagtttag atcataaagg tttaaacgga acagctaatg gatttggtgt
     9901 gtacttaaca cctaataaag aaatggctac aatgtacgct gaacagggta gtaacggaaa
     9961 taatggtttc gtatatgaag taaatgttga attagagaag ccgatttcta tgaatgaacg
    10021 cactattact gatgaagagc tttctaaagt aatagataaa ttacaagaaa gtaatgatat
    10081 tttaaatgat tacaatgatg ttagttatta cggagaaaaa gttgtaaaaa gagaagtgat
    10141 tgcttctctt agtgagaatg aaaatgacgt agatttgatt aacgacattg gaaatacaat
    10201 tggagatcat gaagctactg ctaaggcatt ttatgacgtt gggaaatata cacatattat
    10261 tgcggaagaa cagttaagac aaaaggatgt agttatcgta gtgttacagc ctgataaagt
    10321 aaagattgaa actattcacg atttaaacga ggaacggaat agcttagaaa gtagtgagga
    10381 catgacagat aaatttgttg ggcataaggt ttcggaagtt cccattcgag aagttgtgat
    10441 aaaagatttt gagcaagagc tagaaacaac taattattat gacaaacaag cttggcaaga
    10501 gcgcattgaa tacttagaaa acatggaaga accagtttcc agattagcat tagatagtga
    10561 tattaatgaa ttttatgata gtcataaaga agaaattgaa acgaaattga caaatttatc
    10621 cgaaaagtta gagatcgata aagaagaact gctaggtttt ccagtagata cttcttctac
    10681 ggaatacaaa aaagctacgt ctatcatggc ttacaacggt gcaatgagag aaatttataa
    10741 tgaaattgaa aatgatacgt ttgaaatacc acctgtttct gaagaaatgg agaataagat
    10801 tttgaaattg actaattttg aaaatacaac aaaatttgaa atggagtaga taaatgaatg
    10861 atagaacaag aaaatagaaa ttttttagaa acgcaaggtg aatatcgtca aattaataat
    10921 agtcattttg taatttgtga agatgtacaa atcgctttta aaatggcttt gaagtacgga
    10981 aaaagtatta gaaaaaagat aattagagaa aaaaagagca agaagatagg cttttgggag
    11041 ttatctctta gggatgggct aaactttatt ttctgtacag aggattatta tgaaaaatac
    11101 aagtgtacct tatcgtaatt ttactagtga tggtctagta aagggggttt ttgtttggat
    11161 ttgaaaaagg caaaaaaagt aagtatcgtt gatttttgca aacaaaatgg gataggttta
    11221 aagcaagatt caagggaata ctatagatta gaagatcatg attcttgtgt aatcagtgat
    11281 cgtaaaaacc tttttaaatg gaactcaaag gatttagggg gagatatttt tgattttatc
    11341 aaagcctact acgattgttc atttaaagaa gcaaaacaga aacttgaaga tagtgattat
    11401 gaagttcatt cgttcaatac aaaagtgaaa aaagctccgt accaatatca gaaagaaaat
    11461 gaagtgccgg tatctgttgc aaagtcttat ttagtaaatg agagaagaat cgatacagct
    11521 ttagtggaag attttttatc taaaggacta attaaacaag ataaaaaagg aaatgttttg
    11581 ttcttatgga aaaaagatca agaaatcgtt gggtgtacgg aacaaggaac tagaaaattt
    11641 tttcatgaag gcaaacaaaa ggatgttaca tggaaaaaaa tacaagaaaa ctctaaagag
    11701 tattcaggat ttaacgtaac ttttggtcaa ccagataaaa tgtatttttt tgaaagtgaa
    11761 atagatttga tgtcgtacat tacacaaaag ccagaaaaag ccgaaaatgc tacgtttgtt
    11821 agcatgaatg gattaaaggt aggtaatgta ttgcatgggg ttacagagca ttataataag
    11881 tttaaatcat tgccttcaga aacagtcctt tgtgttgata atgataaagc cggacgtact
    11941 tttattgaaa ctgaatttaa agaaaaagga attggaagag aagggatagg aatcagtgaa
    12001 gtaaaagtcg atgtaccttt gcgagaggga tttgattgga atgataattt aacaagagga
    12061 aaagaagctt ttaaacgctt caagttagaa gatgtatcaa aaatcgtgaa cttcacacat
    12121 aaattatctc ttaatactcc tgtatatgaa atggaataaa aagaagaaag tagttgatgt
    12181 gttatgaacg atacaatagc aatcttatca gattcattaa ttgatttaga taagacgtct
    12241 acagactata tgattattga agaacaactt aaaaataaaa atccagagtt cgatattcaa
    12301 gaaaaatcat tgcgtattga attaccaaaa tttaaacaaa aaaaattaat aactattctc
    12361 tttgagatta ttgaacgata tgggcttact tattatcaaa tttggacgga taagaaagat
    12421 ggccaatata caaaaggggt aagcatagaa gccgttagag aagacgatca agtaagtatt
    12481 aaagcagttc aacccttaat ggggtataac gaagaattat tgaattgttt aaacgtctag
    12541 tgtaaactag gcgttttttt acattatttg gctacgaata gacagttaat taaactaaag
    12601 aaaaccattg actacaagta gtcattcctg tatgatatag ccatagacta caagtagtca
    12661 aagactcaaa cccttgattt aataaaaagg agagataata gatggagcag acaagaatgt
    12721 tttggtcaga tcgaatgcaa gatcacttgg attgtattta caaaaccaga gagcaattaa
    12781 ataagttaga tactgtcaga tattatttta cctacttcag tgagaatgac gaacaaagat
    12841 gggatatttt tcatgatggt aattacgaag aattttttta cactgaaagt taattatttg
    12901 ttgaaatgat gaaggattct atttgatgaa agggaacgga aaaccgttcc cctaaaaaat
    12961 atccaaatga ctacaagtag tcatggaagg agagcggaat aatggtaaat aaaaaagaaa
    13021 cgtttaaagt aggtatggaa gtacagggcg ttgttattgg gagcggagag cttatcgagg
    13081 gagaagtaat tagtttgtta gctaatgtag cggtagttaa agcaatcgga aaagcaccgg
    13141 tagtgatgaa aaaatgcagc atgatgtgtc ttgatggttt aaacaatcca ataactcaac
    13201 gctttgagaa cgtgatataa tagaaaaaag aagattttct actgggagag attattatga
    13261 aagactatgc ttcacgtaaa tttatccact tagagcctat gaaagaattg gttattaatg
    13321 ggaatgaata taatgattac aaatctttat ttgtaaagga acagcctaaa ggcggtattc
    13381 ggatgaaaaa tttaccggac ttccgattta tcgaagtaaa caatttagga attatagaag
    13441 actatttaga taagttagat gaagcgataa agcaatcaat tgaaaaaaat ggtgaagatc
    13501 atatacttac ggttgtttta aaagacttga aagatagact agaagctgaa gcagagtact
    13561 ttaataaaga ctaataagaa gggaatgaga gctatgacag aggctgtaaa agaattaaag
    13621 aaaatgtatc ctgatgtttt gaatatgact gtagatgatt ttcatgaagc cttaaaaaat
    13681 gcagaaagtg aggaagaaag gactttctac cttacacttt ctagttttgt gacacgagta
    13741 gatcaaaaaa aagtaattaa tcagaaagac tttaaaatat gagtttagaa aatgaaaaac
    13801 cgtattatgt agttgttggg ggcgttaacg gcgccggtaa gtctactatt tatcaagttc
    13861 aaaatttaaa aagaaaagaa cttgatactg atagaattaa tgcagatgaa attttgagaa
    13921 gttttggcgg aaattggaaa aaacaagcag acataaacaa aagtatgcgt gaagttctaa
    13981 gagagatcaa aggtcatttt aaagaaggaa aatcttttca ccatgaaacg acttttggtg
    14041 gtaatccata tcccgataaa atgagacttc taaaggctaa aaaattaggt tatgaatcgt
    14101 ttttaatcta tataggacta gattcaccag aaagagcgat tgaaagggtt aaaatccgtg
    14161 ttgctaaagg tggccacggt gtacctgaag atttaataag aaaaagatac gaattttctt
    14221 taagaaactt agcagagtta gagaaatatt ttgataatgt aagtatctat gataattcag
    14281 atgagttttc ttatatttat gttaaagaaa atcatacagt tgtagccaat aatacgcaag
    14341 aatatgcttg ggttcccaaa gctattcaag agaaaaatgc tgaaactcct ataagcaaac
    14401 aaattatgat ggatatatct caagaagaga tgaatccaaa agaaaccctt gaaagaatat
    14461 attcagcaag tgatgatttt attagtgatc ggttttcaaa agaagcgcaa gtcgatgatt
    14521 tttataggaa ccataaaaat gaaatcaagg aacggattct atcaattagt ttttctacag
    14581 gggtatctca agatgaatta gtaggtcaag ataaaagaag aaattcttgt aaattggcat
    14641 atattaatag tgtaggtgag cttttagtaa aaactgatag tgagctatta agtatggaat
    14701 taaatagaga tagaaatatc caaaaaactg attttgaagt tgaataaaag aagttgtagc
    14761 tgaatcaatt aatagtaaat aaatttaata aggagtgcga aagcacttct tattttttgg
    14821 ataaagtgac tatatgta
//
LOCUS       DADVXB010000066        14573 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.067, whole genome shotgun sequence.
ACCESSION   DADVXB010000066 DADVXB010000000
VERSION     DADVXB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.067"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(247..942)
                     /locus_tag="KB902_001595"
     CDS             complement(247..942)
                     /locus_tag="KB902_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBB6808425.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGAAALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(1032..2132)
                     /gene="ychF"
                     /locus_tag="KB902_001596"
     CDS             complement(1032..2132)
                     /gene="ychF"
                     /locus_tag="KB902_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBB6808426.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(2141..2332)
                     /locus_tag="KB902_001597"
     CDS             complement(2141..2332)
                     /locus_tag="KB902_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBB6808427.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2353..3243)
                     /locus_tag="KB902_001598"
     CDS             complement(2353..3243)
                     /locus_tag="KB902_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBB6808428.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3230..3997)
                     /locus_tag="KB902_001599"
     CDS             complement(3230..3997)
                     /locus_tag="KB902_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6808429.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(4009..4722)
                     /gene="rsmG"
                     /locus_tag="KB902_001600"
     CDS             complement(4009..4722)
                     /gene="rsmG"
                     /locus_tag="KB902_001600"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBB6808430.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRRLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4954..6855)
                     /gene="mnmG"
                     /locus_tag="KB902_001601"
     CDS             complement(4954..6855)
                     /gene="mnmG"
                     /locus_tag="KB902_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBB6808431.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYADLLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6872..8269)
                     /gene="mnmE"
                     /locus_tag="KB902_001602"
     CDS             complement(6872..8269)
                     /gene="mnmE"
                     /locus_tag="KB902_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBB6808432.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHVVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDAGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8569..8952
                     /locus_tag="KB902_001603"
     CDS             8569..8952
                     /locus_tag="KB902_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808433.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(9120..9878)
                     /locus_tag="KB902_001604"
     CDS             complement(9120..9878)
                     /locus_tag="KB902_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBB6808434.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9896..10714)
                     /locus_tag="KB902_001605"
     CDS             complement(9896..10714)
                     /locus_tag="KB902_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6808435.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10711..11067)
                     /gene="rnpA"
                     /locus_tag="KB902_001606"
     CDS             complement(10711..11067)
                     /gene="rnpA"
                     /locus_tag="KB902_001606"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBB6808436.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11185..11319)
                     /gene="rpmH"
                     /locus_tag="KB902_001607"
     CDS             complement(11185..11319)
                     /gene="rpmH"
                     /locus_tag="KB902_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBB6808437.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11842..13176
                     /gene="dnaA"
                     /locus_tag="KB902_001608"
     CDS             11842..13176
                     /gene="dnaA"
                     /locus_tag="KB902_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBB6808438.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13374..14504
                     /gene="dnaN"
                     /locus_tag="KB902_001609"
     CDS             13374..14504
                     /gene="dnaN"
                     /locus_tag="KB902_001609"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBB6808439.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         4050 a         3070 c         2623 g         4830 t
ORIGIN      
        1 ggaagaggtt gtgaaatcag cgtcctgacc tgagtattag agaaaaaaac ggaaaaacag
       61 tttctcatgt ttgttgaata ttgtgatttg cgatcgagga gctggaggag aacaccgttt
      121 atcgtaaaaa gggactgtga caagactttt gtcacagccc cttactatta tttaactatg
      181 gataaacaaa atgaggttct ttactacccc tagatatcta gcaaaatagc tgatcttttt
      241 gctagtttat cttcttggga cggataaact tccaataatc ccgtattttt tcttcaagta
      301 gtaacggatt gctaaagcag ctgccccgat aatgataact actactggat ctaatactgg
      361 attgataact ggtggcaata gtgttgtcgc agaaaacagt acgacccaaa gaagtgtcgt
      421 tccacctagg ataagcaatg tcttacccat tcctggtttc ttgcttcgat ctgctccggg
      481 atattcatat tgatagatgt atttgtacat catataaaag acccagccac cgattgcaga
      541 acctaaaacg agtgtagaaa agccataagc tggcgttgtt ccacgtgaaa acaatccggt
      601 aatcgcaatc atgatactta atagaccaag caacagcaac gtattatcta accacatcaa
      661 taaaggggtg gatgaatttt ttacttctgc tggcttattg atgattgctt ccgttctttc
      721 agagactgtc ccaaacaatt gacgggctgt tcttccgcct ttttgttctg caactaaagt
      781 aggcagaatg tcatgaaggg cttttacttt ttcttcttca gacaaattcg ctgcttctaa
      841 agattttttc aaatcaaaaa tgtactgttg atttcttttg gttaattttg tttctaaact
      901 attgttttct tttacgattg ctcgtaattg ttctggttcc attatctaat agtcctcctt
      961 agccgttcct tttctcaacg gtcgtcacaa aagacattct accatattct acagctagtt
     1021 tgatagccct tttacacatt aaagcggaat aacattacgt cgccgtcttg tacgacataa
     1081 tcttttcctt ctaatcgaac acgtccagct tcttttgctg catgcatgtt tccgtaatga
     1141 tccaagtctt caaaagagac agtttccgca cggataaatc cgcgttcgaa atctgaatgg
     1201 atgattcctg ctgcttgtgg tgctttgatt ccttttttga atgtccaagc acgtacttct
     1261 tgttccccag cagtaaagta agtagctaag cctaacaaat cgtaagcagc acggatcaac
     1321 tgatccaaac ctgattcttc gattcctaaa gcttctaaaa attccgcttt gtcttcttca
     1381 tctaattctg cgatttcttc ttctgcacga gcactgacca cgatcacttc tgcattttct
     1441 tctgcagcaa agttgcgcac ttcttgtaca taatgattcg cgtctgcatc tgctacgtca
     1501 tcttctgaga cattggctac ataaagaatt ggttttgtcg tcaataaaaa tagtgattta
     1561 acgatttttt gttcttcttc agtaaattcg atcgttcggg cagattttcc ttcttccagt
     1621 acaggtttga ttttatccag tacagctagt tctgccactg catctttatc tttagtttta
     1681 gcaacttttg ctacacgagt atagcgtttg ttgatagatt ctaagtctgc taacactagt
     1741 tccaagttga tcgtatcaat atcttctagt ggatcaacac gtccttctac gtgagtaata
     1801 ttatcatcat caaaacaacg aacaacgtga caaatagcgt ctacttggcg gatatggctt
     1861 aagaattgat ttcccaaacc ttctccttta cttgcgcctt ttacgattcc agcaatatct
     1921 gtaaattcaa aagtcgttgg aacagttttt ttcggatgta caagttctgt taagcgttgc
     1981 aaacgccagt caggtacttc taccatccct acgttagggt cgatcgtcgc aaagggatag
     2041 tttgctgctt ctgctcctgc ttttgtgatc gcattaaaca aagttgattt tcctacgttg
     2101 ggcaacccaa caattccagc agtcaatgcc ataaatttat tcactctttc tctgcatttt
     2161 tttcaattac tttttttaat ttcttttcaa aatctcgacg ggtcatcatg acgatatgtc
     2221 cgcaattcat acatctgatt ttgatatctg cgcccattcg aatgacttcc cagcgattcg
     2281 tctggcaagc gtgaggtttt ttcatttcaa cgatatcgtg caagtcgtac ataaaaatag
     2341 cctccttttt gtttattctt catcaaattg aatattcaag atatcaagaa ttcgagtcaa
     2401 atctttttga gaaagatatt caatctcaat cttacctttc ccattttttt cttggatagc
     2461 tacacttgta ccaaatttat ccatcaaacg atcttcgctt tctcggatat aatatggttt
     2521 ttcctttgct agccttggga tttttttctt ttcttttcca tcattttgat ttaactcaga
     2581 aacaagctgt tccagttggc ggacagttaa attttcagtt actgcacgat tggctaattt
     2641 caaaatcaat gttttatttt ttaaacctaa cagcgtacgg gcttgtccca tagataaacg
     2701 ctgatcttgt accatttcct tgacaagatc cggtaaagaa agcaagcgca aataattggc
     2761 gatataaggt ctgctctttc ctaaacgact agctacttct gcttgtgtta gtttcaggtt
     2821 tttcatcagc atctcatatg cttctgcttc ttctaacgga ttcagatctt ctcgctgcaa
     2881 gttttccagc actgctactt gcatcatcgc ttcttcgtca aagtctctaa cgatagcagg
     2941 gattgtttct ttttcagcta gtttggacgc tcgaaaacgt cgctcccctg caataatctc
     3001 atatcctttt actgcggaac ggcgtacgat gatgggttga aagacgcctg attgttcaat
     3061 agaattagct agttcctgca aagatacttc ttcaaatgtt ttacggggct gatacggatt
     3121 tggtcgcagc tcattcaatg gtagctggac aacggtatca tcttttacat ccaccgtctc
     3181 taagttttct aaatcttgaa acagtgcatc gattcctcgg cctaatcctt tacttttctt
     3241 cacgacttac cacttccttt gccaatgctt ggtagacttc agctcctcga gaacgtggat
     3301 cgtagtcgat gatcggtttt ccatgactag gtgcttctga caaacgaata tttcttggaa
     3361 tgatcgtttc gtaaactttt tcgcggaagt atttacgtac ttcttctacg acttcatttc
     3421 ccagatttgt tcgtgcatca tacattgtca gtaagactcc ctcgatctct aattctggat
     3481 taaagtgttt ttgaactaaa cgaaccgtat tcagtaattg gcttaatcct tccaatgcgt
     3541 aatactcaca ctgaacaggt atcaaaatcg aatcacttgc tgtaaatgaa ttgattgtca
     3601 gatggccaag agaaggcggg caatcgatca aaatataatc atactgactg cttacttctg
     3661 ctaaagatcc ttttaatctt gattctcttg ccatcattga cgtcaattcg atctctgctc
     3721 ctgctaattg gagagtcgca ggcacaatac tcaaattttc gtgttcagtg atcaaagttg
     3781 cctcatcaat tggcaattca ttgactagaa catcatagat gtctcttgtc acatcaggtt
     3841 ttctgatccc gacaccactg gtagcatttc cttgcgcatc catatccact agcaatactt
     3901 ttttaccaag gctagcaaga caagcaccta gattcaccgt cgtcgttgtt ttgccgacgc
     3961 cacctttttg gttcgcaaca gatattattt gtgccatctc ttctcctcct atttgattgg
     4021 ctgcttatta ggcagtccgg gctttcttgg gtatttcttt ggggttggtt tctttttttg
     4081 aataacgatg atatgccgtt gatcagagac attcggcaag gtaaccgcct cttctttgag
     4141 gaatttacca cctaataaag caatcgcttg ttttgcttct gtcaattcct cttcactttt
     4201 tgctgctttc aatgcataaa aatagccttc ttgtttagcc aagggcaaac acaattccgc
     4261 taacacattc aaacgagcaa ccgcacgagc agtgacaagg tcaaatgatg cacgaaagtg
     4321 aggattttgc ccaaatgttt ctgcccggtc atgatataag gaagcatcga ttcctaataa
     4381 tcgggttaac tcagataaga aggttattcg tttattcaga gaatcaacga tcgttatctg
     4441 cagttctgga aaggcaattt ttaaaggtat gctaggaaac cctgcccccg aaccgacatc
     4501 gcataaagat aaaggctgcg taaagtctac ttcaaatgct aatgtaagtg aatcgtaaaa
     4561 atgcttcaga tatacgtctt tttcatccgt aatagctgta aggttcatct tttcgttcca
     4621 ttcgactaat ctccgataat aaatagcgaa ttgattcatt tgatgatcgg taagctctat
     4681 ccctttttct gccaaggatt ggcgaaattc ttctggtatc ataaatattc ctttcattgt
     4741 gaaacagcaa ttgtttcaca gattctctcc ctactttaac gcaaaatccc tagacatgca
     4801 atccttccat atggattctt aaaaatttga aaagtaagaa aagccgatag actttttctt
     4861 tctagtatga ctcataaaat atacacagaa gagagaacta gctttgagca atttctgcaa
     4921 aaactagttc tctcttctat ttattatcac gtattacgct ggttcactga ctttcgcaat
     4981 cttcccttgt tcgatataga ccattaggat acttaggtct gcagggttta cgccactgat
     5041 tcggctagct tgggcaattg tttctggttg gattttctgc aatttttgtt ttgcttctgt
     5101 tgctaatccg ttgattgctg cgtagtcgat gttttctgga atctttttcg cttccatgcg
     5161 ttttaatttt tctacttttt ccatggcttt tttgatgtag ccttcatatt tgatttggat
     5221 ttctacttgt tcgatttctt ttcgtgtcaa ttcttcattt tctggaataa accgtagaag
     5281 atctgcataa gtaatctcag gacgtcttaa aaagtcgctt gctagtacac catcttttaa
     5341 tggtgccgca ttaatcgttg ctaaaaagtc ttggacttct tctgttggtt tgattcgtac
     5401 attcatcaaa cgtttgattt cttgttcaac tgcttctttt ttcttcaaat aattcttgta
     5461 ttgatcttct tttactaagc ctacacggtg acccatttct gttaatcgca aatctgcatt
     5521 atcatgacgt aaaagcagac ggtattcagc acgtgaagtc agcaaacgat aaggttcgtt
     5581 cgttcctttt gttaccaaat catcgatcat gacaccgatg taaccgtcac ttcgtttgat
     5641 cactaaaggt tcttttccct gaactttcaa agctgcattg ataccggcaa tcagcccttg
     5701 tccagccgct tcttcataac cgcttgtacc atttgtttgt ccagctgtat aaagattttc
     5761 aacgacttta gtttctaatg tcggacggag ctggtgtggc tctactacgt catattcgat
     5821 agcatatcct gtacgcatca tttctacttt ttctaatcca gcaatagaat gaagcatgtt
     5881 gacttgaaca tcctctggta aagaagtaga taaaccttga acatagactt cttccgtatt
     5941 taagccttct ggttccaaaa ataattgatg acgtggtttg tctgcaaaac gcacgatctt
     6001 atcttcgatg gatgggcaat agcgagcgcc taccccttca acgatccctg taaacattgg
     6061 ggcacgatgt aagttgtctc gaataatttg gtgagtcgtc tcacctgtat aggtcagcca
     6121 gcaagattcc tgatctagtt tataggcact atctggtgtg ctgaagctaa aatgattcgg
     6181 ctctttgtca ccaggttgct cttctgtaac agaatagtcg atcgtacttg attttactcg
     6241 aggcggtgtt cctgttttga accgttcgat agcaaagcca agttctttta gatgattcgc
     6301 tagtccaata gaaggttgag agttattcgg acctgatgaa tatttcaatt caccgataat
     6361 gatttctccg cgaagtgctg ttccggctgt aataacaact gctttggccc ggtagctcgc
     6421 tcctgtggaa gtcactactc catgacaaac accatcttcg acgatcagtt cttcgacgat
     6481 tccttgtctt agcgtcaaat ttggttcttt ttcgatcgta tgtttcattt ctgttgaata
     6541 agcatgtttg tctgcttgtg ctcgcaatgc tcggacagct gggccttttc ctgtgttcaa
     6601 catacgcatt tggatatagg ttttatcgat attcttaccc atttctccgc ctaacgcatc
     6661 gatttctcga acgacaacgc ctttagctgg tccgcctaca gaaggattac atggcatgaa
     6721 tgctaccatg tccaaattta ttgtcagtaa tagtgttttt gatcccatac gtgcagcagc
     6781 aagtgcagct tctgaaccgg cgtgtcctgc gccaacaacg atcacgtcat acgcatctgc
     6841 ttcataatgt tccaatcgtt tgttcctccc tttattttcc taaacaaaat tgactgaata
     6901 attgagtgat tagctcatct tgtacactgt cgccgacgac ttctcctaga tagtcccagc
     6961 aacgcgtcat atctatttga acgagatcca caggcattcc tgcatcaata cctgcaatga
     7021 cttcttcaag tgagagggaa gctttttcta acaacgcgat atggcgggta ttagaaacat
     7081 aagtagcgtc tctttctcct gtttctccgc tgaagaataa atcagaaata gctgattcca
     7141 aacgatctag tccgtcgttt ttagctacgg aaattgaaaa aactggttca ttttcgatca
     7201 atttcttcaa tttttcttgt tccagctgtg ctggtaaatc tgttttattt agaagaatga
     7261 tccgtttcaa tccacttgtc gcttccaata attgttcatc ttctgctgtc agtggttcgc
     7321 tttggtttag aacaagtaag atcaagtctg cttctgctaa tgcttttcgg cttctttcga
     7381 ccccgatccg ttccaccaca tcttctgttt cccgaattcc agctgtatcg attagcttga
     7441 gcggtacccc ccgaacattg acatactctt cgattacatc tcgagtcgtt cctgcaatat
     7501 ccgtaacgat tgctttttct tctcttaaca aatggtttaa caaacttgat ttgccgacat
     7561 ttggccggcc gatgattgcc gtacttaacc cttcccgcag aaccttccct tgcttggatg
     7621 tagcaagtag cgcttggatt ctttgttgga tcatctgcgc tttttcaagc aataacttcg
     7681 tagtcaattc ttcgacatca tcatattctg gataatcaat atttacttct acttgtgcta
     7741 atgtctctaa aatctcttgt ctcaatgagc ggatcaaagc agacagattg ccgtctaact
     7801 gattaagagc tagtcccatt gctttgtctg tttttgcccg aatcaaatcc atcacagctt
     7861 ctgcctgtga aaggtcaaca cgaccattca agaatgctcg ttttgtgaat tcgcctggct
     7921 cagctaatct tgcaccttct cttaacaata gctgcaaaat ttgattgact acaacgatcc
     7981 caccgtgaca attgatttct actacatctt cccgcgtaaa tgtctttggt gctctcatca
     8041 cggagaccat gacttcatcg acaagctgat tgctcttggg atcaacgaca tgtccataat
     8101 ggatcgtatg acttggtact tctgataatc gtttgtttcc agattgataa actttatctg
     8161 ctagttgcac agcttgatcg ccacttaaac gaacgatact gattgcacct tctccaggtg
     8221 gggtagaaat tgccgcaatc gtatcaaatt ctaaagtaat ttcagccatt ttttcacttc
     8281 ctttttcatt ttgcgcacaa aaaaagtgcc cactccaccc tttatgcaca ataaacggtg
     8341 aacttcgcac tttgactgct tgttcttgat taaattctgg tcatagatta tcacacttgc
     8401 tataaggaat caagtgttta aaacaagtta gatgaagttg agcctgttct gcttccatta
     8461 ccttatattt gattgtcctt ggatgtctct ttgcgttctt tggtttattc gaagagaaga
     8521 tactgtataa acaaggcttt atctttctta aaaaaaacgg tacactaaat ggtagcgcta
     8581 tctaaactat acacttttga aaggagaaaa tatgtgagcc cgttcagatc tgctgcattg
     8641 gaagaagaaa gtgaccctcg gatcaacgat gtcgttttat ctacagggaa tatcaaccag
     8701 aaatatatcg tccgcgatat cgtttttgtt gtggaatgct tagaagctga tttgtttgac
     8761 ccatcttttc ccaaagatga ccttttctta acaacgaaga ggaaattaaa gacgaaggta
     8821 cttgaatatg gtgcgaatgc agtaatcaac tgtcattttg agtatcagca aaaaaaacgc
     8881 gacggaaagt attttctgga actttttgct tatggaacag tgatccaatt tatccaaaca
     8941 acgattggtt aaatgaaaca gacaaaaaaa gcggatcaaa actgaagaca gtttcgatcc
     9001 gcttttttct atcaaagtta gtgactactt catcgtatac tctgataaga atgatttcta
     9061 gtaaaatata cttggtttga aaaactttgt caacgtgatt tattcaaaaa gtaatggaat
     9121 caataatatt ttttagcagg ttctactact aaataacgat aaggttcctc accttccgaa
     9181 tgtgttttta catgttcatc tttgcttaat gcagcatgga tttgtttacg ttcaaatgca
     9241 ggcattggtt ctaagaaaac aggctgccct gtccgtttta ctttttcagc cgtgcgatca
     9301 gctaaacgct gaatgatctc ttggcgcttt tcacggtaat tgcctacatt gactactaca
     9361 gacagcttat ttcttgctaa acgatggatg aagacttgtg ccagatattg caatgcattc
     9421 agtgtttttc catgtttccc aatcagtatg ccttgctttt gtgtttctaa atggaaaaca
     9481 accatattat ttgattctct ttccattttg acaagagctg gagcatcaag ctgttttgaa
     9541 atttcagtaa gataaactgc caattccgtt aaagctgctt catcacctag ctcacttact
     9601 tcttctgttt tttcttcaag aatcgtttcg ttgactacct cgatctcagc tgttggttct
     9661 tcttccaaaa tttcttctac agtctgttct actgtttcag aaactttttc gctgatactt
     9721 ggctggatcg aaagccgtgc attctttcga cccattccta ggaaaccttt ttttccttct
     9781 tccagtattt cgatttcgac ttggtctttg gccaaaccca aatcagccag acctagttgg
     9841 acagcttcgt ctattgttgc agcttcataa atcggcatta gcattacctc ccctattatt
     9901 tccgtttttt cttaggattc attgctttct taagagcacg ttctctttcg cggattctcc
     9961 gtgcttcttc ttcacgctct tttcgaattt tgaaagggtt gttgatcagc agcgtttgta
    10021 caacttggaa ggcattggaa actacccagt ataatgaaag accgctggct aaattgacac
    10081 ccatcactaa aatcattaca ggcatcacga aattcatgat cttcattgat gcattcgatt
    10141 caatttgact catgctagat aaatacgtac ttgcaaaagt aaagattgct gctaaaatcg
    10201 gcaaaataaa tgttggatcc gcgttcccta agttcaacca taagaaatgc ccttgtttca
    10261 actctggtac acgtgaaata gattgccata acgccatcaa gattggcatt tgtactaata
    10321 aaggaagaca accagcatat ggattgacgc cattttctgc atataaacgc tgctgctctt
    10381 ctcttaactt actttgtgtt tccggatctc ttgaactata ttgttgctgc agtgctttta
    10441 atttcggttg taattcttgc gttttacgca tgctctttgt ttggaaatgc atcaacggca
    10501 ataggatcac gcggatgatc agtgtaaata aaatgatccc tatccctgca ttaccaaatg
    10561 acaacgcctt gatcgcctca gcaaagtaat aaacaatata acgatcccaa attcctgtac
    10621 tctgtgcgct gacttcccca gttccgcaac cggataagac gatgaccaaa ctaacgatac
    10681 cggccatcaa aagtaaacgt ttgtatttct tcacttactc ttttcctctc tgtcgattat
    10741 ttttgcaagt tttaagacgt ggactaaatt ggagcgaacc tcatcataag tcaacccctt
    10801 cacacttggt ctagcaatca caataaaatc caactccgga tcaatctctt cttttataga
    10861 ataaactgct gctcggattt ttcgtttgac ttcattgcgg tttaccgcgt tgccgacctt
    10921 ttttcctaca gataaaccaa ctcgaaaatg aggctgtccc ggtttttcca aacggtaaac
    10981 gacgaatttg cggttagcaa aagaatctcc cgtatggaac acggcttgaa actctcgttc
    11041 tttttttact cgatacgctt ttctcattag ttttctttcc ttttctatct ctcacttacg
    11101 ctcataatca taccataatt acgattgtcc tttcatcatt tccctaaaaa agagtataaa
    11161 aaaaaccact gaaaccccag tggcctaagc tgaaagaact tttcttcctt tgcgacgacg
    11221 gctagctaac acacgacgtc catttttagt actcatacgt ttacggaatc cgtgaacttt
    11281 ttgacgttta cgtttatttg gttggtatgt tcttttcata tattccacct ccaaaatgtt
    11341 cttatctatt ttataaacac agacatactt tgatagtata acgacaaagt agtgattttg
    11401 tcaatataaa atagaagatc gattgttaaa acttatccac aagattattt ttttctatgg
    11461 gagtcctatg tggaaaaagt tatgcacagg gattatccac agataataaa tggctggttt
    11521 tacacagaaa acacacgtgt aaaaaaagta atccacaatc aggtgattcc ctgtgtattc
    11581 cgtctcctaa ctattggtat atctatattt tttatccaca gacgcaagag gaaatctatt
    11641 gatttttacg agttttccac ctgtgcatta gtggtgtgga aaactttttt tgacaactgt
    11701 gtttttctct tttttctttt tgtcgattgt gtggataatt gtaattaaaa aatttttttc
    11761 ttcggtttct gtggaaaact attgaaaaaa atgctaaatt agtactagtt attcactttt
    11821 taatgaagga ggaggcctta tatggtatcc ctcgatgctt tatggaatga attaaaagca
    11881 acataccaaa aggatttatc gcctgctagc tataatacat ggatcgaaac agcgaaccct
    11941 cgaacccttg atcaaaacca gctcgttgtt gaggttccta gcaagattca taaagaatat
    12001 tgggaaaaaa acctggcgac aaaaatcgtt gaagtcggtt atatgttatc aggaaatgag
    12061 attatccctc gctttattac tggcgaagaa gcagagcaag aagaagttat agaagaaaaa
    12121 aatccaaaag ttgtggcacc tagtccgcta aaaaaagcca tgctgaaccc taaatatacc
    12181 tttgatacgt ttgtcattgg taaaggaaac cagatggctc atgcagcagc gctcgttgta
    12241 gcagaagatc caggttctat ttataacccg ctcttctttt atggaggcgt gggacttggt
    12301 aagactcact tgatgcatgc aattggtcat caaatgctgc aaagtcagcc taatgccaaa
    12361 gtaaaatatg taagcagtga aacttttgct aatgatttca tcaattcgat ccaaaacaaa
    12421 acagcagaag agttccgtca agaatatcga aatgttgatt tactgctagt ggatgacatt
    12481 caattttttg cagaaaaaga agctacgcaa gaagagtttt tccatacttt caatgccttg
    12541 tacaatgaag ggaaacaaat cgtactaacc agtgatcggt tgccaaacga gattccgaaa
    12601 ctgcaagaac gcctcgtttc tcgctttgca tgggggctgt ctgttgatat tacaccgccg
    12661 gatcttgaaa caagaacagc gattttacgt aaaaaagcgg cggctgaacg tctagagatc
    12721 ccagatgaca cactaagcta catcgcagga caaattgatt ctaacattcg tgaattagaa
    12781 ggtgcgcttg ttcgagtgca agcttttgct gcgatgaata gtgaagatat ttcgactagt
    12841 ctagctgcag acgcactgaa aacgttaaaa tcaggaaaag gacatcctca attgtcaatc
    12901 ctgcagatcc aagaagaagt ggcaaagtat tatcacatcc aattgaaaga tctcaaagga
    12961 aagaaacgcg tcaaatctat tgttgttcct agacaaatcg ctatgtattt ggcacgtgag
    13021 ctcacagata attctttacc gaaaatcgga gctgaattcg gtggcaagga tcatacaacg
    13081 gttatccatg ctcatgaaaa aatccagcag ctgatggatt ctagtgtcag tatgcaaaat
    13141 gaagtatcag aaatcaaaaa ctttttacta aattaatttg tcgattctat caactgaaaa
    13201 tagcatgtgg ataaaagaaa aaaacgttca aaagttatgc acactttttc cacagctgtt
    13261 ttttcgtttc tctcttacgt tttttgagtt ttccacagaa tcaacatgcc ctattacttt
    13321 tattattctt tttaactaat aataaataaa caaacattca aaggagatac atcatgaaag
    13381 ttactttaaa ccgagctagc tttatgcagg aattgcaaac tgttcaacga gctatttcaa
    13441 gcaaaaccac gatccctatt ttgacaggtg taaaaatcac actgacacaa gaaggtttga
    13501 ctttgacggg gagcaacgct gatatatcaa ttgaaacttt tttgtctgtt gaaaacgaaa
    13561 aagcaaatat gcaaatcgaa tctactggtt ccattgtttt acaagcacgt ttctttagcg
    13621 aaatcattcg gagacttcct gaagaaacat ttactttaga agttttagaa aataaacaag
    13681 tagcgattac ttctggaaaa gcgaatttta tcgtaaatgg attagatgca gataactatc
    13741 ctcatcttcc tgttgtcgaa agccataacc agatgaaatt acctgtacac gtattgacta
    13801 aactaatcaa cgaaacagtt tttgctgtct cacaacatga gagtcgtcca atcttgacag
    13861 gtgtgcattt cattttatct gataattctt tattggctgt agctactgat tctcaccgtc
    13921 taagtcaacg cgtgattcca gtagaacaag cggctgatca ttttgatatt gttattcctg
    13981 gaaaaagttt gatcgaatta tctcgctcat taacaaatga agaagaaatc gtcgaaatca
    14041 gcattatgga aaaccaagtg ttgttcaaaa cagaaacgat gtatttctat tcccgtttgc
    14101 tagaaggaaa ctatcctgat accaatcgtt tgattccttc aagttttaat acagaggttg
    14161 aattttctgt tcctagcttt ttagcggcga tcgaacgggc ttctttactt tctcatgaag
    14221 gccgtaacaa catcgttcgt ttatctattc gtccagatgc ggttgtttta tacggaaatt
    14281 cgccagaaat cgggaaagta gaagaaagct tgagttatac agcaagcagt ggcgatccat
    14341 tagatatttc tttcaatccg gattatatga aagcagcgtt gcgtgcattt ggagatatga
    14401 gcatcaaagt gaaatttatc tctgctattc gtccatttac attggaacca acggaagatg
    14461 gcgttcaatt tattcagctg attactcctg tacgtacaaa ttaacaatga ttttcattgt
    14521 tcttgaaaat ttaattgaaa agaaatagaa aaaataaaat tttaaacaga agg
//
LOCUS       DADVXB010000067        14355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.068, whole genome shotgun sequence.
ACCESSION   DADVXB010000067 DADVXB010000000
VERSION     DADVXB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.068"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..325)
                     /locus_tag="KB902_001610"
     CDS             complement(<1..325)
                     /locus_tag="KB902_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6808440.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQI"
     gene            complement(325..555)
                     /locus_tag="KB902_001611"
     CDS             complement(325..555)
                     /locus_tag="KB902_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6808441.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            842..1180
                     /locus_tag="KB902_001612"
     CDS             842..1180
                     /locus_tag="KB902_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808442.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(1385..1624)
                     /locus_tag="KB902_001613"
     CDS             complement(1385..1624)
                     /locus_tag="KB902_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6808443.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(1600..1947)
                     /locus_tag="KB902_001614"
     CDS             complement(1600..1947)
                     /locus_tag="KB902_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6808444.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(2679..3260)
                     /locus_tag="KB902_001615"
     CDS             complement(2679..3260)
                     /locus_tag="KB902_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6808445.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(3443..4069)
                     /locus_tag="KB902_001616"
     CDS             complement(3443..4069)
                     /locus_tag="KB902_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6808446.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4091..5422)
                     /locus_tag="KB902_001617"
     CDS             complement(4091..5422)
                     /locus_tag="KB902_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBB6808447.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(5577..5978)
                     /locus_tag="KB902_001618"
     CDS             complement(5577..5978)
                     /locus_tag="KB902_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6808448.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6064..6270)
                     /locus_tag="KB902_001619"
     CDS             complement(6064..6270)
                     /locus_tag="KB902_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808449.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(6365..7867)
                     /locus_tag="KB902_001620"
     CDS             complement(6365..7867)
                     /locus_tag="KB902_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBB6808450.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7885..8340)
                     /gene="argR"
                     /locus_tag="KB902_001621"
     CDS             complement(7885..8340)
                     /gene="argR"
                     /locus_tag="KB902_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6808451.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(8438..9055)
                     /locus_tag="KB902_001622"
     CDS             complement(8438..9055)
                     /locus_tag="KB902_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBB6808452.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            9276..10649
                     /locus_tag="KB902_001623"
     CDS             9276..10649
                     /locus_tag="KB902_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6808453.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10724..11836
                     /locus_tag="KB902_001624"
     CDS             10724..11836
                     /locus_tag="KB902_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBB6808454.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11908..13545)
                     /locus_tag="KB902_001625"
     CDS             complement(11908..13545)
                     /locus_tag="KB902_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBB6808455.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13713..14321)
                     /locus_tag="KB902_001626"
     CDS             complement(13713..14321)
                     /locus_tag="KB902_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6808456.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         3891 a         3004 c         2541 g         4919 t
ORIGIN      
        1 taatctgatc aattttagcc atgtcttgca atggtaagtt ttctattttt ttgagttttc
       61 gttccttaaa atcaagagat tttaattgtg taataattac ttgtcctttt atatctagct
      121 cttcaggtaa tgagtaacgt gtcggtaaat tctttatagt ggaagtaatt ggacatatga
      181 ccgaaaacat tgttttacgg ttaaattcat aacgagagac gactagtcct ggtcgtcttt
      241 tttgaatttc ttttcctacg gagggatcaa aatcaatcca tacaatatca ccttttttag
      301 gaatataaat tctttcttct gacactataa aatttctctc ccttcaggag ttaaatcttc
      361 ccattcgtct ttctcataat actcggcctc ttccccacca ctaaatggat cttcaatttt
      421 tggaactaac gtaattgttc catcatcaga atacacaacg atatattctt ggttttctga
      481 aggtttcttt ccgttatcag aaggtaaagt taccactaca gaacttcctt gtaatctaga
      541 ttttgtaaca agcattatca tcactccctt aataaaagta tactatataa cactaagtaa
      601 cgcaaaattc ccctttgtaa actatctaga aaattgtttt gtttaaagta tatcttattg
      661 gatataaata gaaataaatt gtagccagtt cattttttct ttaactaaaa aaataatcca
      721 agaaacattg aacctatgga tccaaaagct acccaaatac tatagctaac cccccgctac
      781 cttcaatttt gcagataaaa cgctttggga gaaaatttca aagacaacag gccatcctat
      841 catgcccgat tataaacaaa aagctggcta ttccttttgc tctgacaaat ttcaattggg
      901 aaagttcacg aaactagcag gtgaagaagt ttcaactgtt cggatcaaag aatgcccgct
      961 tcaaatagaa acattggttc aacgaatttc aactagacaa gactttgcta ttgtagaacg
     1021 tgagatcgta gctatttttg tagaagaagg gattttacat gatccaactc atatcaatgt
     1081 ggataaatgg caacctctta tctataaatt cagagaatat acaactgcca accagtcgtt
     1141 aactttgaat tttagattcc aagaattcaa agagtcataa tgataaacat cgttaggtat
     1201 aaataaaaaa gactcgcagc acgagtaaaa aacaaataga agctatacat tagaaaggtc
     1261 gactgtgacc ctatagatgc agtatatgca gcttatgagc atttcttctg ttctctttgt
     1321 ttttgggatc tgtgctgaag tctttttcgt tttttgccgc tctttctttg aaaaatcgat
     1381 tatgttatac cttctccatt actaattcag gcatctgctg agtaatgatt tttcgcgcaa
     1441 aagaaatatc tgttacccaa ggttcgattt gttcttcagt caagacaagc ggcattcggt
     1501 catggattgg tgcgactgtg cggttaggtt cagtagtcat tatgattgat tctgccattt
     1561 tttcatcctg atggctacga taaaaaccgc caatatacac tattttttcc ttatttgaaa
     1621 acataaattt gtctttttct tcattccact cattgggaaa acacaacgat tttgcaaaaa
     1681 tggttgatga aaggtctttt tttcttctac tgtctctgca cgggcattaa tcatcaattg
     1741 tcctttttta aatccggtaa atccccactt catgatttcc ggagtgagga tgttttcttc
     1801 ctcttttctt aacgtcacaa caagatttga cggaaaaact tctccagctg ctaattctgc
     1861 tgcctgcttc ggttgtttcg tctgggcttc tcgataataa ttctgaagga gctctgactc
     1921 tagatcaaaa aaataacgac cacacatcct aatccctccc aatctttttt tctatcatac
     1981 actgcaacaa gaagttcgca ccaacaaaac gctttcaatt tttgtagaac taaaaaagtt
     2041 gtgacaagtg acaaactctc cagtgaatgg tattctcctg ccaactcctc ggtcacaagt
     2101 cacaatattc aacaaacatg agaagctgct ttttgaaatt gttccttgtg actcggagtg
     2161 aaacggcagg cttacgacct ctgggtaaac ggtgttcaaa agccagtttc tcggtattaa
     2221 gccaaattta tgcaaaaatg tagaaagcta ttttcacaaa atttttctta atactcgaaa
     2281 ctaagcgact ttttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta
     2341 ataagcccaa ccaaacgaaa aatatgagca gctattttta tttggctgtt cttattactt
     2401 gatgcagggc agctttttca caacctctcc actaaacggt gttcaatcag ctaaccttcg
     2461 gtattagctc aaaaaacggc aaaatatgag gaactatttt gccgtttgtt tctctaatac
     2521 tcaggtcaaa gcgctgattt cacaacctct aatacacggt gttccagaag tagcttcttc
     2581 gaaaaataag ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat
     2641 ttcttgaagc tgaccacttc tgtcacaacc tctaattatt aaagaacctt ttgcgaagtt
     2701 aacaatcttt ctttgatcaa ttgaaaattc tgcctaagta gtgatagatc ctgtgtgact
     2761 ttcaacaata agatacttcc ctggatttca gcaatcaacg ctttggcttg acggtctgct
     2821 tcttcatcgg acagtttttc ttcagaaagt gccaggatat tttgtttcgt atacttgacc
     2881 cattgattga ctaattctag tagcaacaga cggtattctt catccactgt actcaactca
     2941 ataatcaaat tacctacagg acagccatga taagtgatct gtgtctcatg atcagcgaaa
     3001 atccagtcca acatttcttc taatgcttct tctggctgtt ttccagcatt taagatgtct
     3061 tcgaacaatt ctgtctgcca tacgtccata tgcgcatgga tcaccgctag acaaacttct
     3121 ttttttgaag aaaagtaata ataaaattga ccttttcctg tatcagaagc tgctagaata
     3181 tctcggattg acgtttcatg atagcctttt ttataaataa gatctttggt cgcttccaag
     3241 atcttttcct ttgttttcaa tgatattctc ctttttcatt tctcatagtc ctatattata
     3301 cagtaaattc atcatttttt cttcttaatc gtttaaaaaa gactgtgcca aattatctga
     3361 cacagccctc actataaaac tgttctcata tagctagatg ttcattgatt caagaactgc
     3421 gaggacaaaa gcaattccta tcttatgata gttgctctaa tacttcctct gttgtcatca
     3481 cttgatctgc aataaagcca aagttcgtca acgctgcatc cattgcttct tggccaggag
     3541 caccaattgc atctgtcgct accacaacat tgaatccact ctctaccaat tcacgcatat
     3601 gggaatcgct acacaagttt ccgttcattc caccaagaat tactgtgtcg attccatttt
     3661 ttctcaattg gagcgccaaa tcattgcttt ctggtccaaa gattttatga ggagagctga
     3721 tgatcgtatt ttcatccaaa taaggtttca attcttcgat aaaatcggct cctgaacctt
     3781 cttccactga ttcatattga ctttttctag caaacatctg ctgctcaagc atcatatgtt
     3841 ctcctgcacc gccaaattgc catttatggt catgtgggta aaaataatga ggagaaataa
     3901 agagtttgta tcctttttct tttgcttgtt ttaccatttc aatcatattt tcgatcgtat
     3961 tgtatttttc taagatatct tttgtcaaac caaagccacc gcctgctggt ttcaagaact
     4021 cgacttgcgg gtcagtgaga actactgctg tatttttatt attgaacatg gtggattctc
     4081 cattcgttat ttattttaat acatcattta gagcttcact cattgtcgga tgagaataga
     4141 tttgatctct caataacgta taaggaagtt ttccattcat agctagcgaa atcaagttga
     4201 tgacttcatg agaatcttcc gcatagatac ttgcccctag aatcaagtca gtttcagggt
     4261 cgactaaaac tttgaataca cctttaggat cttctaatac ttgtgcttta gggacaccgc
     4321 ttgtcatata cttgaataat ttgtaattga cgccttgtgc tttggcttgt ttttctgtta
     4381 aacctacatt ggataaagtc ggagtgataa atacactgta aggcacagct ttccggttat
     4441 tcgttgttcg tttattctcg cccttcaact gatccataat gattcgataa tcatctagag
     4501 agatataagt gaactgcaat ccgcctttga cgtctccaat cgcccaaatg ttgtctgcat
     4561 ctgtacgaag gtattcatcc acagcgattg ctccgcgatc tgttagttta acatctgtat
     4621 tttctaatcc aagtgatgct gtacttggtt ttcttccagt tgcagccaaa acttttgacg
     4681 cttggattgt tacttcttgg ccatcttctg taaaggtgac ggcagctgtt gattcttggt
     4741 ctgctacttg atctacagat acacctagat ggaattcgat tcccgcattt gtcatgtctt
     4801 ctaaaatcat ttgcgcgata tcttcatctt cacgtggaag aaattcagaa tgggcatcaa
     4861 gaacgacaac tttagatccg tattcattga acattgatgc aaattccaag ccaatatatc
     4921 cagccccgat gatcactaat ttttccggta attgttcctg atccatcgct tgcgtagaat
     4981 caatcaagta gcgacttgta ttcaatcctt tgattggtaa aatgattggt tcagaaccag
     5041 tattgatgaa aatccgttcg ccttcaacaa tcactttttc accattattc gtcacttcga
     5101 tttgatggtt agaaagaaaa cgtgctgtac cgtccatcac tgtcccagtt gcctcatcgc
     5161 tgatcatatg ataatttttg gcgcgaagca tgcccgtcaa tttttctttc cgagcaacag
     5221 cctctgtaaa gtcgattcct ctttctccat tgaaaatcaa tgatttagaa ggaatacagc
     5281 cgatgttgat acatgttccg ccatacatac gtgttgactt ttcaacgact aaaaccgatt
     5341 caccttttga agctaacgcc ttcgctaaag tcttaccgcc ctttccaaaa ccgatcacaa
     5401 tattttgata tttttccatc atttttccct cgcttctttt ttacctaccg attggtacaa
     5461 aaatatgata accgataatt gtctattctc caaatcatct gctttatttg tcaaaaaaaa
     5521 ccagacaaaa agcggtcctt tcacgttttt agtctggttc gatttccttt attcttctaa
     5581 acaatcgtta cttctacatc gatatttcct ctagttgctt tggagtaagg gcagaattca
     5641 tgcgcatctt ctgcaatttt ttgggcttct tcttcgctga tgccatcgat atgcacttct
     5701 aatactacac cgatctgata gccgccatca tctaaattat aaagagagac acgtgctttt
     5761 actgtggact ctgctgtcat tcctgcttct ttgatcatat gttgtaccgc cccattgaaa
     5821 caagaagcat aacctgctgc aaataattgt tctggatttg ttccttctgc atggattcct
     5881 ggaggagtga ttttcatatg catcgagcca tttggtgcct cgacttctcc attgcgcccg
     5941 ccatggttga tcattgctgt ttcgtatgct tttttcattg tactgctcct ttcgattgac
     6001 catttgctac ttggctataa ttatagtgta tgacaagtaa ggcgctttct acaaaaattc
     6061 tgcttattcg aataccagaa tgccgtcttc tactattttt ccaaaaaaca aaaaaatact
     6121 actcgtgaac aacagcgtca tatttgttcc aaaataaata gcaatctttt ctacataatc
     6181 ttttatatga ttgattttaa gatacatata taccagaaag ttgaccccat aaaccaatac
     6241 tgttaaaaaa ataaccatat tcgttaccat tttttcctcc ttttgctggt ctccctacca
     6301 gcactcgatt taaccatacc actttttttg ccgtccaagc aactagcctt tcaaaaagac
     6361 tggtttattc tgctgttaat gattcaagat cagaaaaatg tccgaataat tttgctaatt
     6421 ttactaacgc caacttgttc tttccgaatt catcattttc tatctgtaat actagtaacg
     6481 gctcatgtaa gcttaaacgg atcaaaaacc agccgtttcc gtatggctct tctagatcat
     6541 atcgaatacc ttcttcattt tccgggtcga agttcatccc tttttcttct tccaacagtc
     6601 gcttcatttc ttctaatatc ttgtttcctt gttcgcgtgg ttcatcgctg aacaatttta
     6661 atcggatttc ttgtacttct acgggctgtt tcaactcttt gatttgttca tctaatgtga
     6721 taccttttct ttttaattct ggcaaaagca tcaggatctt tgcgatgaca tatgcaccat
     6781 catccagaaa atagttttcc ttgaatgcag cgtgtccgct tgtttcgatg gctagctgtg
     6841 tatctttccc aagacggtta agttctaatg ctttattgat tacatttcga tagccggaaa
     6901 tataacgaac ttggatgcct cctttttctt caatgaatct ttgtagatga gaagaagtag
     6961 gggaattcgt cacgattctt gttcctggat gctcttttaa tacgattgta cttaatactg
     7021 cgatcaaatt atttcgattg atcactgttc cagaagcact gacaactgca gaacgatcca
     7081 catctgtatc gaaaatgatc ccaagatctg cttcatttgc taaaacagcc tgcttgatac
     7141 tttccatcgc ttctttatta tcaggatttg ggatatgatt aggaaatcgg ccatctggtt
     7201 ccaaaaattg ggaacctgtt gaatccgcac ctaagctatt caatactttt tcagcaaaga
     7261 atccaccagc accatttccg gcatcaacaa tgattttcca accatttagt ggtttgcttt
     7321 ctagtgttcc aatccccttt ttaatttttg tgactaaatc ttgcgcataa ggtgtcaaaa
     7381 ggtctgcttt ttctacgctt ccagtttgtt cgctttttat tttttgctgc tgtgatagga
     7441 taaaagcaat atcttctttt tctgctcctc cttctgaggt aaagaatttt attccattat
     7501 aataataggg aagatggcta gcagtcagca taaccgcagc atcgcacgag aactgttcaa
     7561 attgagtgga cataaacata gcaggcgtag tagctaattc gaaatcgatg acatgtatcc
     7621 cttgttcttt cagactttgg atcaacgcct ctttcagtgc tggtccgctt atcctactgt
     7681 catgaccaat cccaatcgtc cattttttat ttggatcggt tgatttcttc tttttcttta
     7741 tccagtttgc tagtccccag ccgatctttt ttaccatgtc tgtcgtcaag tttacttcat
     7801 atccttcaac tggtaatgcg attcctcgaa tatccgatcc attttgcagc gctttcatat
     7861 ctttcatata aaagtcctcc tcatttattc cctcattttt tccagctttt ctgcaaatcg
     7921 ctgtgcttct tcttctgagc ggcaaataat aatgaatgta tctacaccgg ccatcgttcc
     7981 gacaacttca gggtaagcca cttcatctag ccaattcgtt accacatcgg caccatttcg
     8041 ttcagtcaat acgataacca tgaactgaac agactggata cgcaaaacct cgcgtctaat
     8101 tgctgtacgc aaacgttctt catttaaaga aacagatggc tggttaaata atgtatagcg
     8161 tactattttg ttttcatttt gactttttac taacttcatt tctcgaatgt ctcgagaaat
     8221 cgttgcttga gtcacatcgg cgcctgcttc atgcagccgc gcaagcagct cttcctgtgt
     8281 cccaataggt tgttctgtaa tgatctggcg gatcagtgct tgtcgctgtt tctttttcat
     8341 attagacacc tctcaatgtt gattatagca aaagataagt aatatttctt catattttgg
     8401 tattttttac ttttattttt tgttttcatt caggttgcta acctttttct attttaacac
     8461 gcaaaatcgt cttcattttt tcaggtgctg attttcttgg atcgctgatg taaatctctt
     8521 tgtgttcttt agaagctctt tcatagcctt cttttgcgat gaatgcttct aatttctcaa
     8581 acgttgctgg ttcttcggca tagggcccga cgtgtaagat ttgggcacaa agaccttctt
     8641 ccatcttttt gaatactact tgttctttca agtcttccgg aagtttgcta gaacgctgaa
     8701 tggcttcttg tgctatcgct tctgtaacaa agtcaggctg tcggatcatc aattgataag
     8761 aaaaatgttc ttttttcatc actggttcat gcaaatactt ttcttgcagt ccccattgtc
     8821 cttccagtgg atagacagta tacatctgat aatcaggaat cagccaattt tttttaggcg
     8881 acatgcgtat tgcatagctg actgcatata gacaggctac tcttcgttta aagtcttcct
     8941 gattcgggtc gccgatccct ctgatgctaa agaatgattt tttaggaacc tctagtattt
     9001 gcgggctttt tttcatacta tagctcttgt ctttacgcca ttcaattttt tccatttttc
     9061 ttcctccgcg aaattccatt tagttattta ttatcatacc tctttttgag tgacttggct
     9121 aatcgtgttg acactatttt tcagtttgtg ctagaataag tgaagtaaat aaatcgtaca
     9181 gataacacgt ttcggcgtgt cgagagagag gcggtttcta tttttataat agaaatcact
     9241 ctcttttttt acgaaatttt ttagaggtga tgtaaatgac aaaacaaaaa cagctgcttt
     9301 tagtacctgc agtaattgca acagggatga tgtcttttgc gggcgtattg atcgagacgg
     9361 ccatgaatgt aactttccca actcttatca gacagtttga tttaacgact gcacaagtcc
     9421 aatgggtaac aacgatttat cttttgatga tttcgatcat tgttccgctg tctacttatt
     9481 tgaatcgcaa ttttagtctc aaaaaactct ttttagcttc aaatctgctt ttcttggcag
     9541 gtataatgat cgatttcttc tctcctacct tcatggtcct attgtttggt cgattgctcc
     9601 aaggtgcagc gacaggtatc gctcttccgt tgatgttcca tattatcttg acatttgccc
     9661 ccctcaatcg acgaggcgcg atgatgggtg tcggtacttt gacaacggcc attgctccag
     9721 caattggccc cacttatgga ggcattatga cttcacattt tacatggaat catatcttcc
     9781 tgtttcttgt gcccgttttg tttctttctt tgattatcgg ctggtttgct attcccgaga
     9841 tggcagtaca aaaaagtggt tatttggatt ggataagcgt tttaggaatt tgtcttttgt
     9901 ttagtggaag tctaacattt ttgagtacgt tgggaacagt ttccagctgg attgctttaa
     9961 tcatcggcgg tattggctgg ttcctttttt actatcgaag taaaaaagtg gagcatccac
    10021 tgatccgact gtctattctt tcaaataaaa cattccgctt gtttttgatt ggcttcttag
    10081 tttatcagtt tttattactt ggtgtatctt ttgtcttgcc gaatttcctt cagatcgttc
    10141 aaggaagtag tccttttgtc gctggattag cgatgcttcc cggcgcagcg gttggtgctt
    10201 tgctttctcc tttttccggg aaaatgctgg atcaatatgg tccgaagaag ccaatttttg
    10261 ctgggctgat tctttctttg attggttggc tagcattatt cctactcata ggacacgctt
    10321 cagtgggtgt attgattgct tgtcatgtgt tttatatgat cggtatcgga ttatcttaca
    10381 gcaatatgat gaccaccgga atgaatgcac tgaatgaaga actacaagga gacgggaacg
    10441 caatgttcaa taccttgcag cagttttctg gcgctgtggc tacttcatta gtagcggtca
    10501 ttatcaatta cgtccagcat catacttccc ataactatga agtgtctact acattaggat
    10561 caaaagcagc attaggcgtc ttgttgctgt tgcttctcgt aagctttgct cgattcgcct
    10621 attatctgtt ctttgctaaa aaagcgtaga ttccatatac ggcaggtgtt gcatctgccg
    10681 tttttttgtg tgaaaatggt tgtttgtaaa aggaggcttt tttatggaaa aaattgccat
    10741 tatcggtggc gggatcattg gtatgaccct agccagttac ttagatacat caaaattcaa
    10801 tgttgcttta tttgatgaag ggacaggaca ggcaactaaa gctagcgctg ggattatctc
    10861 cccttggttg tcgaaacgca gaaacaaaca atggtatcgt ctggctaaag acggcgctgc
    10921 ttttttccct aaacttataa aagatttcca acttgatcaa acgatttacg cacaatcagg
    10981 gacacttttg cttcgacctg aaaaagattt agctgaattg gctgttcttg ccgagaaacg
    11041 aaaagaagaa gcgccagaaa ttggaaacat cgaatggctt tcacctgaac agacatctca
    11101 agcacttccg ttattgaaac cagcagtttc actgcgtatc agtggtggtg gtcgtctgga
    11161 tggaaaagca tatttagaac atcttggtca gcgtttagca caaaaacaaa tggagcagat
    11221 ccaggcaaaa gtcactttgc ataagaagag cgattcttgg ctcatcaagg gaccgtttgg
    11281 agaatacaca gctgatcgtg taattttgac acctggcccg gcacttaagc ctttattaca
    11341 agaattaggc tatgctgcag atatacgtcc gcaaaaaggg cagctcttag catttcagac
    11401 atcttataag atgagtcaag actggcctgt tgctatgctt gacggagaag ctgatttcat
    11461 tcctttcatg gatggaaaga tccttttagg tgctacccat gaaaacgatc aaggctggga
    11521 tttggctcct actagcgaag cttataaggg attgactaag agtacagaac agttcttgac
    11581 tgatccagat cagataaaaa actggccata cgagttccgt gtaggtaccc gtgcttatac
    11641 gtcagatttt tccccatttt tcggcgtact gccagatgat ccaagcttac tggctgctag
    11701 cggtctaggc tcttctggct tgaccacagg tccttatatc ggctatctat tagccaactt
    11761 cttaaatact ggtcattggc ctacggaaga ttatcaaaag gacatctcca cctatattac
    11821 gaaaaatcca tcatagaaaa acagcttttt caagtaagga tcccgagcga tattgcgcat
    11881 ggattacttc ttgaaaaagc tgttatttta gttcaatttc tgaatcaaat tctccaaact
    11941 ttcttttgct tcatctggca agagatcttt tcctatctga gcttcaatga atcgtaaacg
    12001 aatatcaagt cgttgtttca ccagattttt ataggacgta tcctcaaaag aaacaggaaa
    12061 atctggtata ggtaaatagt ggatgtcttc aaatggacca aacgacttga attctgccgt
    12121 ttgttgcacg attctttcaa cgattgacaa tgtcgtttca ggtttgattt ttttatcatc
    12181 gaaatatcca gtattcagga catagcaggc tgtttgctgt ttcaaaaaca actctcgaaa
    12241 agcttgatag tcttccctaa gaggatagac acggaaagga ttagcaaatg gttcaatgac
    12301 tagctcatct agctgtcttt ttgtagtgat attttccgcg tctgatcgtt ttgttgctaa
    12361 tgttgcacca aaagacgctg ctaaaactgg gtcattgatc ttgataattg gcggaagcga
    12421 atcatctttc atgatccaaa aaacagcatc gatcttttcg ctaagatgat cgactcggtc
    12481 gggtgtcgca taacgtgatt tgactgtccg cccatttccg tttcgtatat ctcctgttac
    12541 taggactttt tctcctttac ttgtacatgt cacgcccaca ttctgacaag taaggaaaga
    12601 agaaatggcc ggatcatcag acggatagtc ttgtgtttta tcaaagtaag aaggttccaa
    12661 ggcagtagca aaaccatttt ttcgagaaat aacgaaagca tcgtcatgca agatcgaaac
    12721 agagtgacct tccgtatgtt ttgctaaggt aatcgttgat tttccagaac cggacaaccc
    12781 aaatacagcc atcgtatagg tctggtcatt actagcatat tgtttcatcc caccgtggca
    12841 ggcaataaag ccattgcgat ttcccaatgc ccaagcaagc gtcaaagtcg ctttttttaa
    12901 ttctccaaag taacgtaatc ctagcacagc cgctgtatta tggagagcat caaacaaaat
    12961 gagtccattt ggaaatgttt catgtgtcca ttcgggatca caaaagatat aaagatctcc
    13021 ctcatcaaag gaaacagact tttgataagt ctctaagatc ttcgaattcg ctggctgaaa
    13081 attcagcaaa taagaataca aattgttctc aaatccttct ggaatcagca aatgactttg
    13141 cacagaaaat tcttcagata ggccaacgat tacttttgta tggtaaaact ggcgcttgcg
    13201 actttgatac acagcttctc ttaaaatttt ctcgtatttg ctttgttcct tgtctaagtc
    13261 ctcaaagatc cgccgagcac ttgctgttct tcccacaatg cttccatcat tgaatactag
    13321 tgtcctaaca tcagctggta aatctagttc ttcagcatgt gagattgtta aatctgtgat
    13381 gatcgttcct ggactccctt ttgctagttg ataagctgtc ttcctatcaa aaacttcatg
    13441 aacattatta ccgtaaaatg tcgtttctac aatcgatcga atactggata acagtggatt
    13501 tccacttgtg atttcgttta attcgagact ctcttttgta ctcatggctc ctcctcattc
    13561 cctaaacaaa aaaacgtttt ctttattata cattattcga gtttttattt gtactgctgc
    13621 gctgtgggaa gcaaacgagt tatttttcac acaaaaaaac cgagaacttg aataaacaag
    13681 tttctcggtt tcatcatttt ccttttatcg gcttagtacc agccgtttgc taaccagaat
    13741 gttttagcag catcccatga accataacga gatgttacat attgttctgc tacacgttct
    13801 tgattggcag ctgaatagtc gccgtttaag tatgaagcat ctaattgata acggccgatg
    13861 taacgtccgt tagtagctgt gtatgaaccg cctgattctt tttgtgcgat ccattctttt
    13921 gcagagcttg aagttggcgc tgttgcagca gctggggcag caggagctac ttcaactgtt
    13981 tcaacaggtg caacgtatgt atgttcttgc gttgctgttt cagttgtaga tgctgtattt
    14041 tctgttgttt tgttttctgt tgttgctgaa gaatcatttg aagttgggat tgttaattgt
    14101 tcaccaacat aaatgcggtt gatgtttgcg atcgaatttt tttcagcaat tgcatcgatc
    14161 attgagttgt ctcctgcaaa tttttgtgag atcttagata atgaatcacc tgattttact
    14221 gtataaactt catcagcgtg agcatttgta gttcctacaa acattgcagt agcaccagca
    14281 gcaaaagttg tacctaaaac aattttctta aatgaattca tattaaactc ctttttttct
    14341 ccgtttttta ttctt
//
LOCUS       DADVXB010000068        14346 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.069, whole genome shotgun sequence.
ACCESSION   DADVXB010000068 DADVXB010000000
VERSION     DADVXB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.069"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..412)
                     /locus_tag="KB902_001627"
     CDS             complement(<1..412)
                     /locus_tag="KB902_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HBB6808457.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPL"
     gene            556..906
                     /locus_tag="KB902_001628"
     CDS             556..906
                     /locus_tag="KB902_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6808458.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            887..1603
                     /locus_tag="KB902_001629"
     CDS             887..1603
                     /locus_tag="KB902_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808459.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            1603..3051
                     /locus_tag="KB902_001630"
     CDS             1603..3051
                     /locus_tag="KB902_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6808460.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(3121..3630)
                     /locus_tag="KB902_001631"
     CDS             complement(3121..3630)
                     /locus_tag="KB902_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808461.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(3620..4345)
                     /locus_tag="KB902_001632"
     CDS             complement(3620..4345)
                     /locus_tag="KB902_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808462.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(4568..6688)
                     /locus_tag="KB902_001633"
     CDS             complement(4568..6688)
                     /locus_tag="KB902_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6808463.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            6918..8096
                     /locus_tag="KB902_001634"
     CDS             6918..8096
                     /locus_tag="KB902_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBB6808464.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            8112..8870
                     /gene="aroD"
                     /locus_tag="KB902_001635"
     CDS             8112..8870
                     /gene="aroD"
                     /locus_tag="KB902_001635"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBB6808465.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            8893..9378
                     /gene="ybaK"
                     /locus_tag="KB902_001636"
     CDS             8893..9378
                     /gene="ybaK"
                     /locus_tag="KB902_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBB6808466.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(9449..10702)
                     /locus_tag="KB902_001637"
     CDS             complement(9449..10702)
                     /locus_tag="KB902_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6808467.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            10819..12168
                     /gene="gdhA"
                     /locus_tag="KB902_001638"
     CDS             10819..12168
                     /gene="gdhA"
                     /locus_tag="KB902_001638"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBB6808468.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            12280..13626
                     /locus_tag="KB902_001639"
     CDS             12280..13626
                     /locus_tag="KB902_001639"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBB6808469.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(13934..14320)
                     /locus_tag="KB902_001640"
     CDS             complement(13934..14320)
                     /locus_tag="KB902_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6808470.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         4701 a         2545 c         2931 g         4169 t
ORIGIN      
        1 ctaaaggatc aatttccgga acatctgaat gaatgaagtc gtaagcattg atcattgttt
       61 ggctatgacc ggtacaccag attttctgat cgttatagta agaaagttca tgaccgttca
      121 actgtacatg atcatacatt ttttgacatt cttctgaaga aaatgtttga gaatagattt
      181 cttcgccgtc tactcgaatg aaagaaccat tcatggtgac cgcagaagta atgcccgcat
      241 cttccatgat agagtggatt tctgcttctg tacgtcctgt agcgatgacg gggagaacat
      301 tgttttcttt taatgcgttc atagcttttg ccacttcggg tgtgattttt gatttcgcat
      361 ctagtaatgt tccatcaaga tcaaagaaag tgattgcacg ataatttgac acaaataaaa
      421 ctcctttttt attggaataa gtttatctta acaaagaatg aacaaaagac aaacctttcg
      481 tgaagaattc ctgaacatat tggttcagtc aacaatttag agtatactat aagaagagaa
      541 tttaggaggg aaagaatgat ttttttcagt attggtatct tattcttaat aattggcagt
      601 ctttttcgga ttctgccctc aaaaggaaat ctgccttttt atgggtatca ttcgcctctt
      661 gccgcaaaaa cagacgctca ttggcggctg gctcaaaaga caagcggaaa ctggtttttt
      721 cttatgggct tactgatggc attgatcggc tattatttaa agacatctgg gcatacgaat
      781 tattttctga ttgaaatgct tctgctagta tttccaatta tgcctatttt tattatgaca
      841 gaaaagaaat tacagaaata tgacctggaa actggaggga acgataatga atattttaat
      901 gattgaagat aatcaatctg tttctgaaat gatgcagatg tttttcttaa atgaaggttg
      961 ggaagcaact ttcaagtatg atggaaaaga agggctcgat gcctttttag aaaacccaca
     1021 acattgggat atgattacac tagacctgaa tttgcccaca ctggacggta tgctagtagg
     1081 aagagagatc cgcaaagttt caagtactgt gccgattatc atgctgacag ctagagattc
     1141 tgaaagcgat caggtgatcg gcttagagat gggggcagat gattatgtca caaaaccttt
     1201 cagtcctctg acgcttattg ctcgaatgaa agctttgcat cgccgtagtg agttggcaga
     1261 agcaagagaa gaagcagtag tttcagatga tcattttgat atcgagacta gtcatttcaa
     1321 gatgaatacg aaaacacgag aagcgtatct ggacaaccgg ccaattgaag gactgacgcc
     1381 taaagagttc gatctattgt ttactttagc aaaaaaacca cgtcaagtat tctctcggga
     1441 gcagttgctt gaattagtct gggattatca gtactttggt gatgaacgga cagtggacgc
     1501 ccatatcaag aaattacgac aaaaaatcga aaaggtcgga ccacaagtca tccaaactgt
     1561 ttggggagtc ggctacaaat tcgatgattc tggtgttgcc taatgcgtta tttgtatcag
     1621 caactcttag ctttctgcgg aatggtcgcg ttgatcttat tgatcgttgg agtttctttt
     1681 acacaactga caaaacaaac gattgaagaa aacaattacc agcaactgtt tggatatgct
     1741 gaatcagttg aaaagacaac gcaaacctat gccgatacgc tcccgcagtt tagtcaagat
     1801 caggcgtttc aaaatgcatt gctgctgaca gagcaagtac tgacagaaca aaatgtgaac
     1861 tttatattta tcgataaaaa cgaacgtgtc atttatccga ctaatacagc tttactgaat
     1921 tttaccttaa cagctgatca atggaaaaat ctgaggaatg gacgtcaaga aaaattcaca
     1981 tcgaataaaa atattttagg acaagcacag gcgacctctt acgcacttgt gccatttaat
     2041 ttgaatcatg aattctatgg agcacttgta gttagtcaac ctgcgcgaaa tatcgataac
     2101 agcgttcgtc caattacact gaacctgttc aaaggattta ttttttccag tatcgttgca
     2161 gttattgcca gctatgcttt tgcagcattc caagttaagc gtatcaatcg gttaaggaat
     2221 gcgacgaaag aagtgacgaa tggtaatttt gatgtacagc tccccgtaca tgacaaagat
     2281 gaatttgatg agttagcaga tgatttcaat aaaatgacga attcattgaa agaatctcaa
     2341 gcagaaattg aagaacaaga aaatcgtcga agacaattta tggcagatgc ttctcacgag
     2401 atgagaacac ctcttacgac aatcaacgga cttctggaag ggttagaata caatgcaatc
     2461 cctgaaaatc agcgagaaaa cgcgattaaa ttgatgaaaa atgaaacaga gcgtctgatc
     2521 cgtttggtga atgaaaactt ggattatgaa aaaatccgta cgaatcaaat cagtatggtc
     2581 attaaaaaat tcaatggaac agaaacattg aaaaatattg ttgcacagtt agaagctaaa
     2641 gcagaagcag caggagatac attgacattg aaagccgttg atgatattga tgtttacgct
     2701 gattatgacc gatttgtcca aatcatggtc aatattattc aaaacgcgat acagtttact
     2761 gaaaacggcc aaatcacgat tactttagaa aaaggctatc ttgaaacgat catcacgatt
     2821 gaagatacgg gaattggaat gtctgaacaa caaatgaaaa gtatctggga tcgttattat
     2881 aaagtagatc cttcaagaaa aaatacaaaa tatggtgaat caggattagg tttaccaatc
     2941 gtgcagcaac ttgtacgctt gcataaagga aaattagaag tagaaagcga actaggaaaa
     3001 ggaacaaaat tcgctgttcg tttgcctgac gtagaaatca aaaaagagta aaaaacaagc
     3061 ggtataaaag atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat
     3121 ttagcccgcg ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt
     3181 aaagagtaag ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc
     3241 ttggatctcc aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt
     3301 ggaaagcaag gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc
     3361 cgcacaatta agcaaggaag gagagatatc aagtttttct tgataggcca aacgatcttg
     3421 tttgatttct ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa
     3481 catcggccaa tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt
     3541 tttcaagtgc tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg
     3601 ttcagcatga atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat
     3661 ggataaaaaa agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa
     3721 gagtttgggc aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg
     3781 taaaaaaagt ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac
     3841 ggatatctgg cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt
     3901 cataaactga ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag
     3961 gaaagaacag ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggt
     4021 gccaattgat caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa
     4081 ggaaggcaaa tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt
     4141 ctaaagccgg aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga
     4201 cttgattggc taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag
     4261 cagaaaagct tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag
     4321 cagtagcata gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat
     4381 atgaataaag tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt
     4441 aaaaagcaag aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga
     4501 acactgttta ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt
     4561 tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt
     4621 tataaagatc aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac
     4681 caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg
     4741 tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt
     4801 ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta
     4861 cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt
     4921 agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat
     4981 ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt
     5041 gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg
     5101 tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg
     5161 tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga
     5221 caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca
     5281 aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt
     5341 tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg
     5401 aataaggata atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt
     5461 ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat
     5521 tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt
     5581 atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca ctaatgtaac
     5641 cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg
     5701 tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc
     5761 ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt
     5821 ggtaaagact attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt
     5881 tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctc
     5941 tagcgagccc gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta
     6001 cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa
     6061 caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga
     6121 atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa
     6181 tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca
     6241 acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca
     6301 catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag
     6361 cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg
     6421 aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag
     6481 ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa
     6541 acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa
     6601 aaatcgtttt caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca
     6661 aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca
     6721 gaagtgtcct gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac
     6781 aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt
     6841 catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag
     6901 ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa
     6961 aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat
     7021 gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga
     7081 ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg
     7141 aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta
     7201 ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt gttgattatt
     7261 atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat
     7321 tgattcaagc ttttcgtgaa atctacccgg aaatcatagg aggctatgag aaaattcgat
     7381 ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct
     7441 tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg
     7501 ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga
     7561 aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag
     7621 gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac
     7681 agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg
     7741 agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac
     7801 caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg
     7861 tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg
     7921 cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg
     7981 tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct
     8041 ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg
     8101 agcgatgcag aatggttcgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt
     8161 gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg
     8221 aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg
     8281 atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat
     8341 ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg
     8401 acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca
     8461 aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa
     8521 ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga
     8581 atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac
     8641 gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta
     8701 ttattacgat gtccatggga aatcttggta aaatttctcg tctggttggc ggaacgacgg
     8761 gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac
     8821 cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg
     8881 aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa
     8941 caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg
     9001 tcatcggtcg ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct
     9061 gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta
     9121 aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg
     9181 gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt
     9241 cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga
     9301 agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt
     9361 gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg
     9421 tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta
     9481 catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca
     9541 gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa
     9601 tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt
     9661 tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg
     9721 cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct
     9781 caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg
     9841 tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca
     9901 ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg
     9961 gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac
    10021 cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct
    10081 cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg
    10141 tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag
    10201 tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta
    10261 taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg
    10321 tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg
    10381 ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga
    10441 agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc
    10501 caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac
    10561 cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg
    10621 cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga
    10681 tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa
    10741 gaaaacagaa aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga gggaagataa
    10801 gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat tcaagaaaag
    10861 ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga attcatgccc
    10921 acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat cttagaactt
    10981 ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga tgaaggaaac
    11041 tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc ttataaaggt
    11101 ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc ttttgaacag
    11161 attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg aagtgacttc
    11221 gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt catgctggaa
    11281 ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg tgtaggagct
    11341 agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga tactggtgtg
    11401 ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc tactggttat
    11461 ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt taatcaaaaa
    11521 acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa agtgcaagag
    11581 ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga tccagaagga
    11641 atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt gacggaatac
    11701 gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac attgaaagaa
    11761 aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag cttggccgaa
    11821 atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc atgtacagta
    11881 aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat
    11941 gctggaggag tagcagtatc tgctttagaa atgagtcaga acgtccagcg attgacttgg
    12001 gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta ccatacgtgt
    12061 cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct
    12121 ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa aatgaaactt
    12181 tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa
    12241 agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat tcattttgac
    12301 tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca aagccaagta
    12361 acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt ccgcggctgg
    12421 atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa
    12481 aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc ttatttaggc
    12541 gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga tagcaacaca
    12601 agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata tattgctgac
    12661 ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca
    12721 actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga
    12781 caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg tgcagttaaa
    12841 gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat cggcggacgt
    12901 ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc agatatcgat
    12961 gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa actagaagaa
    13021 aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg caaagtaact
    13081 gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg gaaacaattg
    13141 tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc aaacttctca
    13201 actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat ttttgaaaca
    13261 gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc agaagattta
    13321 gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa agcatttgaa
    13381 ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa aattccagaa
    13441 atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt aggtatttca
    13501 ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta caagaaaaac
    13561 atgttcgcac ttctaggcaa accaggcttt gaagatcttg ctaaagaatt gaacgaacgc
    13621 ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca tgttcgcttt
    13681 aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta ttcagaataa
    13741 ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga ttgattgcct
    13801 tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa ggttaattct
    13861 gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg cttttttgcg
    13921 atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt accttatcgc
    13981 tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc aagatcgttc
    14041 cttcggggta agcagaacca ttggcagagt caccagaagt aatgacatcg aaatctaact
    14101 gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct cttccaatta
    14161 cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg actaccgcat
    14221 aataatcttt acctacataa gtagactgat agtagtccca acctttccat cctataaaag
    14281 caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc cttttttatt
    14341 tttatt
//
LOCUS       DADVXB010000069        14043 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.070, whole genome shotgun sequence.
ACCESSION   DADVXB010000069 DADVXB010000000
VERSION     DADVXB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.070"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(45..1340)
                     /locus_tag="KB902_001641"
     CDS             complement(45..1340)
                     /locus_tag="KB902_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6808471.1"
                     /translation="MNDSIKKMLRLIDKNLMITGVSYETFQKEKTLIVDAILSPAPCA
                     CSNCGSTVVDGTGKTIVVKNGKKETIVRFEQYNHMPMVMRLKKQRYTCKNCRTHWTAQ
                     SYFVRPRHSIANHVRYKITSLLTEKVSLSFIAKSCQVSLTTVIRILKEFKSYLPKSSK
                     RILPKVLMVDEFRSHASIEDKMSFICADGETGKLIDILPTRKLPRLTSYFLSCTNPEE
                     VEFLITDMNAAYFQLTKRVLPNAKVVIDRFHIVKHINQAFNDLRIREMNELRKAGKKR
                     QAEKLKKNWRFLLKKRSNINHYEYKTWKSFRAPKYPFFTEAMMIDRLLGFSTPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLEELPETLDDAFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVK"
     gene            1521..1831
                     /locus_tag="KB902_001642"
                     /pseudo
     CDS             1521..1831
                     /locus_tag="KB902_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
     gene            2339..3631
                     /locus_tag="KB902_001643"
     CDS             2339..3631
                     /locus_tag="KB902_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBB6808472.1"
                     /translation="MDGITIPWYAAIIGLIFAVFLILKKMNPVYSLFLGAIIGCLIGG
                     ASLSNTVDILVTGTQSIMGTAIRVLAAGMLAGVMMESGAAESIAHAIVNKLGSNKAIF
                     SLALSTMIITAVGVFIPVAVLIVAPIALSVGKQTGISKLALLTALSGGGKAGNIISPN
                     PNTIAAANGFKLDLSNVMIAGFIPAIFGLATAVLIASLIKKKGGKVKDSDIQEKSEKE
                     LLPLRKALIAPVLSIVLLLINPIGTMLHIQVLADLKIDAMYILPFASIVGTIAMGQAS
                     QIREYSKSGIYRVTDTVLILIGAGAIAGLISVSDLSKQVVHLISITGISGTLLAPISG
                     ILMGLAVGSTSTAVILATGSFGHAILETGTNSLAAAVMVHTGATVIDSVPQGNYFHIT
                     ANSMNMSIKERMKVIPYEICVGGVMTIVATILYGFILK"
     gene            3766..4911
                     /locus_tag="KB902_001644"
     CDS             3766..4911
                     /locus_tag="KB902_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6808473.1"
                     /translation="MEKTFVLAPDSFKESMSAKNACEAMERGIRKVFPESKVIQVPMA
                     DGGEGTVDALVDGINGTKIEVMVSGPIPSEKIKAYYGLLADESTAVIEMAEANGIELL
                     AENKRNPLLTSTYGTGEMIKDALDKGVKKIIIGIGGSVTNDGGAGMAQALGVQFLDKN
                     DKELPVGGGALSELAKVDVSTIDPRLKETEVVIASDVTNPLTGPNGASFVFGPQKGAT
                     PDMVKKLDENLVHYAAVIQKNLGIDIKDQPGSGAAGGLGAGLLVFTGAKMESGVDLVI
                     QLTHLEEKIVQADYVFTGEGGMDFQTKFGKAPYGVAKIAKRYDKPVFACAGYIGEQVD
                     VLYEEGMTAIFGILDQAGPLKQALQAGESNLERTVENIVRVLNVCGG"
     gene            4981..5994
                     /locus_tag="KB902_001645"
     CDS             4981..5994
                     /locus_tag="KB902_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808474.1"
                     /translation="MSNLLTKEQANMIVSKLMADIPYNINIMNEQGFIIASGKEYRIG
                     ERHRGAERAIKQGEMVEIFKDTSLEKRGTNEPIILNGELLGVVGISGDPEEVRPFTKL
                     VKSIVLLLVEELNEFRKKEKKNQLKADFLKELLSIKDCYSEEMVHQALDDYGINLLRT
                     NRCIGSLEQETLRSCFPLHEVFEWYGMYIVFIDGNTIIDDDLSGLIVSSEQWNLGQGM
                     NEVDNTFLYLKFFQIPINKVFFSEDLYFIHLFDFSIKLDKNLLKKVESIYDEYYETLI
                     YFSSNNGNVKEVSEKLHIHRNTLNYRIQRIQELTRKDPKNWSHLWILMYHLAYCFKVK
                     FRT"
     gene            6386..7585
                     /locus_tag="KB902_001646"
     CDS             6386..7585
                     /locus_tag="KB902_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6808475.1"
                     /translation="MRDQTSGKMIRFYYTSLQFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFISQVIIKKRKIPLITVLKTMTAGLGVILLAGVLLPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVVFFVILHLLPDVKNQEVFPMTKEQDRPVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSIASISFAVRGFMMLLAGSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTSFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8080..8838)
                     /locus_tag="KB902_001647"
     CDS             complement(8080..8838)
                     /locus_tag="KB902_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6808476.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLF
                     KDDIVIFVSLNGETKELITAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9006..9941
                     /gene="pfkB"
                     /locus_tag="KB902_001648"
     CDS             9006..9941
                     /gene="pfkB"
                     /locus_tag="KB902_001648"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6808477.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            9938..11383
                     /locus_tag="KB902_001649"
     CDS             9938..11383
                     /locus_tag="KB902_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6808478.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSIIAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAVLFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAATVEMKEETNN"
     gene            11411..11866
                     /locus_tag="KB902_001650"
     CDS             11411..11866
                     /locus_tag="KB902_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6808479.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            11885..12859
                     /gene="lacD"
                     /locus_tag="KB902_001651"
     CDS             11885..12859
                     /gene="lacD"
                     /locus_tag="KB902_001651"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6808480.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNQSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(12969..13454)
                     /locus_tag="KB902_001652"
                     /pseudo
     CDS             complement(12969..13454)
                     /locus_tag="KB902_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
     gene            complement(13614..>14043)
                     /locus_tag="KB902_001653"
     CDS             complement(13614..>14043)
                     /locus_tag="KB902_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6808481.1"
                     /translation="WHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKV
                     VVTDKAPSITSAFKKLKEYGGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTG
                     STTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         4394 a         2263 c         2952 g         4434 t
ORIGIN      
        1 caaatctggg tcaggatgaa cctcattctg gctcagattt tttgttattt cactttgatt
       61 aattgattga tcaaaaagat tctaattctc atgttctcaa atgatttaaa tccgtaggat
      121 actcgtttca ttgtctttat atgggtattc tttgcttcta tttttccatt agaataagga
      181 tagatcatcg cattggtgat gccttcttca taggtcagaa gattttgaag tttctcacga
      241 aaggcatcat ctaacgtttc aggaagttct tccaataaag agaaaaataa gtcagggtct
      301 ttgtctcgaa aggcttctac taactcatga aaaaagggat acgcctcctt caggggcgtg
      361 gagaaaccaa gcaatcggtc aatcatcatc gcttcagtaa aaaatgggta tttaggcgct
      421 cggaaacttt tccatgtttt gtattcataa tggttaatgt ttgaacgttt ttttaacaga
      481 aagcgccagt tctttttcaa cttttcagcc tgcctttttt tacctgcctt acgcagctca
      541 ttcatttcac ggatacgtaa atcgttgaat gcctgattta tatgtttgac aatatgaaat
      601 cgatcaatca ctactttcgc atttggaaga acacgtttgg tgagctggaa ataggcggcg
      661 ttcatatctg tgattaaaaa ttctacttct tctggattgg tgcaacttaa gaaatagctt
      721 gttaatcgag gtaatttacg cgtaggcaag atatcaatta atttacctgt ttcgccatct
      781 gcgcaaataa agctcatttt atcttctata gaagcgtgcg aacgaaactc atcaaccatc
      841 aatacttttg ggagaatcct cttagaggac tttggtaaat agcttttaaa ctctttcaat
      901 atacgaataa cggtggtcaa agatacctga caacttttcg caataaaaga taaagacact
      961 ttttcagtca gtaaagaagt aattttatat ctgacatgat tcgcaatgga atgtctgggg
     1021 cggacaaaat aactttgagc agtccaatgg gttcgacagt ttttacaggt atagcgctgc
     1081 ttttttaagc gcataaccat tggcatatga ttgtattgtt caaagcggac aatggtttcc
     1141 ttcttgccgt ttttcaccac aattgttttc ccagttccat ctaccacagt agaaccacaa
     1201 ttgctacagg cacaaggagc aggtgagaga atggcatcga caatcagagt cttttccttc
     1261 tgaaaggtct cataagagac ccctgtaatc atcaaatttt tatctattaa tctcagcatt
     1321 tttttgatag aatcattcat atagcatatc gtcctctcag tggtttattt tgtcgtgatt
     1381 taatcatact agagaacgat atgtttttta atatctaaaa tgaaaatgag actgaagaat
     1441 caattctgat tcatcagtct cataaattat agagccacaa aactctgtgg tctttttttg
     1501 tagtaaagga ggaatttgga gtggccaaac tagatgaaga atttgctttt ttggtattgt
     1561 cgatcatatc ggagattccc aaaggcaaag tagctaccta tggacaaatt gccgagttgg
     1621 caggatatcc tcgcaattcc cgtttagtcg gtaaagtatt gagccacgcc gaatattatg
     1681 gtcgctatcc ttgtcaacga gtagtgaata gtcagggaga atgtgcgaaa ggttggccgg
     1741 aacagccgtt actattgcaa gagagggtat tatttttcgc gagaatggac gagtggatct
     1801 gaaacgctgc cattgggatg gagaagagtg atctgtaaag gatcattcac tttaagcaat
     1861 acagatatga tgaaataaaa tatctatgaa tttttttgcg ttgcaatgga gagattcttt
     1921 gggagtttga ttctaaaata aatcatatac aatgggttat ttagtgcccg attttgttag
     1981 gagtataggc aaaaagaatt agtagtgaaa atcagtattg tatttgggat atattctttt
     2041 atttaatatg agttaggtcc ttagaactaa aagaattaag agattgattg actttgtaaa
     2101 tagtaaaata cctaataagt atcaatgagt tcccaaatcg tatctagttg aatagaagaa
     2161 atttctattg aatactatgt gattctatga atttatttaa gttgtctaaa atagtgaaat
     2221 tctgaattta tattatcgat atgtgcaaat gaacaaataa cattgtaaat ataccaattt
     2281 tatttatgaa ataaagcatt aaaatgaaaa cgtaaacaat taagaaagga tgtttgaaat
     2341 ggatggaatt acaataccgt ggtatgcggc gattattggt ttgatttttg cagttttttt
     2401 gattttgaaa aaaatgaatc cggtttattc attattttta ggagcaatta tcggatgttt
     2461 gatcggcgga gcatcactaa gcaataccgt ggatatatta gttacaggaa cacaaagtat
     2521 tatggggaca gcaattcgtg tgttggcagc agggatgttg gcaggagtga tgatggagtc
     2581 aggcgcagca gaatccatcg cccatgcaat cgttaataaa cttggaagta ataaagcaat
     2641 cttttcacta gctctgtcaa caatgatcat tacagctgtg ggcgtattta ttcctgtcgc
     2701 agtattgatc gtagcgccga tcgctttgtc agtcggaaag cagacaggta tcagtaaatt
     2761 agcattgttg acagcattgt ctggtggcgg caaagctgga aatatcattt cgcctaatcc
     2821 caatactatc gcagctgcta atgggtttaa attagattta agcaatgtaa tgattgctgg
     2881 atttattccg gcaatttttg gattagcaac agcagttctt attgctagtt tgattaagaa
     2941 aaaaggcggt aaggttaaag atagcgatat tcaagaaaaa tcggaaaaag aattgcttcc
     3001 attacgcaaa gctttaattg cacccgtttt gtcaatcgtt ttattattga taaatccaat
     3061 tggaacgatg cttcatattc aggtgttggc tgatttgaag atcgatgcga tgtacatttt
     3121 acctttcgct tcgatagtgg ggacgatcgc aatgggacaa gctagtcaaa tcagagaata
     3181 ttcaaaatcg gggatttatc gtgtgacaga taccgttttg atcttgattg gtgctggtgc
     3241 tatagctggt ctgatctcag tttctgattt atcaaaacaa gttgtccatt tgatttccat
     3301 tacagggatt tcgggtacat tattagcgcc catctcaggt attttaatgg gcttagcagt
     3361 aggatcaact tctacagcag taattttagc gactggatct tttgggcatg ctattcttga
     3421 aaccggaacc aattcgttag cagcagctgt aatggttcat acaggtgcaa cggtgattga
     3481 tagtgtacct caaggaaact atttccacat tacggctaac agtatgaata tgtctatcaa
     3541 agaacggatg aaagtgattc cttacgaaat ctgtgtcggt ggtgtgatga cgatcgttgc
     3601 aacgatatta tatggattta ttttaaaata aaattgtaga gatagcgttt tgtcaaatct
     3661 tttacaaaaa tatgaacttg aaaaaatatt tattgaaaat aacaatgaag aaggtaaatt
     3721 ctgtttgaaa agaagatttt cagcagaatt ttgaggagaa gaacaatgga gaaaactttt
     3781 gtattagcac cagattcatt taaagaaagt atgagtgcta aaaatgcttg tgaagcaatg
     3841 gaacgaggaa ttcgcaaagt atttcctgaa tctaaagtga tccaagtccc tatggcagat
     3901 ggaggagaag gaactgttga cgcactagtt gacggtatta acgggacaaa aatcgaagtg
     3961 atggtgtctg gaccaattcc atcagaaaaa atcaaggctt attacgggtt gttagcagat
     4021 gaaagtacgg cagtgattga aatggctgaa gccaatggta ttgaactatt ggcagaaaac
     4081 aagcgaaacc ctcttttgac ctctacttac gggactggag agatgatcaa agatgccttg
     4141 gataaaggag taaaaaaaat aatcatcggt ataggaggca gcgtcacgaa tgatggcggt
     4201 gcaggtatgg ctcaagcgtt aggagtgcaa tttttagaca aaaatgacaa ggaactaccg
     4261 gttggaggcg gcgcgttgtc agaattagct aaagtcgacg ttagcactat cgatccaaga
     4321 ctaaaagaaa cagaagtcgt tatcgctagc gatgtaacca atccgttgac gggtccaaat
     4381 ggcgcatcat ttgtttttgg tccgcaaaaa ggagctacgc ctgatatggt taagaaatta
     4441 gatgaaaatt tggttcacta cgctgcggtt attcaaaaaa atttggggat agatatcaag
     4501 gatcagcccg gttctggtgc agcaggggga ttaggagccg gactattagt ttttactggc
     4561 gcaaaaatgg aatccggtgt cgatttggtt atccagttaa cacatttgga agaaaagatt
     4621 gtacaagctg attacgtgtt taccggtgaa ggcggtatgg attttcagac aaaatttggg
     4681 aaagctccat acggtgtagc aaagatcgcc aaacgatatg acaagcctgt ttttgcttgt
     4741 gccggttata tcggcgaaca ggttgatgtt ttatacgagg aaggaatgac tgcgattttc
     4801 ggcatcttag accaggccgg tccattgaag caagcattac aagccggcga atccaattta
     4861 gagcgtacag ttgaaaatat cgtccgtgtt ttaaatgttt gtggaggtta aaagttgtgt
     4921 tatctatcaa aaaaagatta aactaactgt ataaccagat aattcttagg acggtaatca
     4981 atgagtaatt tattaacaaa agagcaggcc aatatgatcg taagcaagct gatggcggat
     5041 attccttaca atattaatat tatgaatgaa caaggtttta ttattgcaag cggtaaagaa
     5101 tatcgtatcg gtgaacgaca tcgtggtgca gaaagagcaa ttaaacaagg cgaaatggtt
     5161 gagatcttca aggatacttc cctagaaaaa agaggaacca acgaaccaat cattttaaat
     5221 ggcgaattat tgggagtagt tggaatctca ggagacccag aagaagtccg cccgtttact
     5281 aagctagtaa aatcaatcgt actgctttta gttgaagaac taaatgaatt tcgaaaaaag
     5341 gaaaagaaaa atcagcttaa agctgatttt ttaaaggagc tcctttcaat caaagattgc
     5401 tacagtgaag agatggttca ccaggcatta gatgattacg ggataaatct tctgcgaacg
     5461 aatcgctgta ttggatcatt ggaacaagaa actttacgta gttgctttcc cttacatgag
     5521 gtttttgaat ggtatggaat gtatatagtt tttattgatg gcaataccat aattgatgac
     5581 gacctctcag gtttaatcgt tagctctgaa caatggaatt taggacaggg aatgaatgaa
     5641 gtagataata cttttctgta tttgaaattt ttccagattc caatcaataa agtctttttt
     5701 agtgaagatt tatattttat tcacttattt gatttttcaa ttaaactaga taagaatcta
     5761 ttaaaaaaag ttgaatcaat ctatgatgaa tattatgaaa cactgattta tttttctagt
     5821 aataatggaa atgtgaaaga agtgtcagaa aaactgcata tccatcgtaa tacactaaat
     5881 tatcgaattc agcgtattca agaattaact agaaaagatc ctaaaaattg gtctcatttg
     5941 tggatattaa tgtaccatct tgcttattgt ttcaaagtga agttcagaac gtaagaaata
     6001 agaatatgta tccataataa atgtttggat ttaccttata gatataaaaa gaaacaaatc
     6061 attctgcagg aatcgattac tcgattcctg ctttttttac ttcctttgca gcaaaaaagt
     6121 gctcgtaatc taagcgatgt tggatagttt ttagaatata tatattttct tcaattccag
     6181 aaaaaaatga ccaagctagt atgctaaaaa agtacgatgc ttctatgatc ttttttccgt
     6241 ctttattaac agatgtttta attgatcaac gcatattgta atctacccta atttccatag
     6301 ttcttcacca cttttaaaaa tagtaaaacc cctacaagta tgctatagta aattgctaaa
     6361 gaaaaaccaa taaggtggga gatgtatgcg cgatcaaaca agtggaaaaa tgattcgttt
     6421 ttattataca agtttgcaat ttctctattg gatgatgttt tgttcggtct atgggtttgc
     6481 gacattgttt ttgatttatt tcaagattga tccagctaaa atcggaggga tcttagcatt
     6541 ggtcaatatt gtttcaacgg tgcttcagcc ttttatcagt caggtgatca tcaagaaaag
     6601 aaagattcca ctgatcaccg tgctaaagac gatgacagca ggattaggag tgattctctt
     6661 agctggggta ttgcttccga atttgccgat cattacttat atcttgggtg ggattttagt
     6721 agtttccatg caatcatttc tcaatgcgct ggcatttgag tattcaaata ccggctacag
     6781 gatcaacttt ggtttttcaa gagctggcgg ttcattttct tatgctgtaa cttctttttt
     6841 actgggacag ttgttagcga tttattctgc cgcgattttg ccgatcttgg ttatagttga
     6901 agcagtagtg tttttcgtta ttttgcatct gctgccggat gtaaaaaatc aagaagtttt
     6961 tcctatgaca aaagaacagg atcgcccagt ttctttgaga aaaaaatatc ctttcctgat
     7021 tttgttgttt ttaggtttca gttttctttt tactttccac accatgatca acagtttttt
     7081 ggcacagatc tttgaaaaca tccacggtgg cagtaaagaa gtcggcatcg cattgatgat
     7141 cgccgcttta tgcgaattac cgggaatgat cttttttgaa cagcttgtca aaaagaaatc
     7201 cagcaaattt tggctgtcta ttgccagtat ttcatttgct gtcagaggat tcatgatgct
     7261 gctggccggt tcgatcttga tgatggaaat gacgcatctc ctgcaagcct ttagttttgc
     7321 tttgtttatt ccagcttcag cttatttatt caatcaattt ctggcggatg acgaccgtgt
     7381 atttggacaa acgatgatca ttatcgccac aactcttggt ggggtgatag gaaatgtctt
     7441 gggcggcagt ctgctgcagc atttcggtgt atgggagatg ctgattttcg gtactagttt
     7501 tgcggtgcta ggtgctttat taactatttt gggcattcga aaaataccga agacaggaaa
     7561 cgatagtgat tctcttgttg agtagcataa aaatacttag atactagttt tatataaata
     7621 acatatagtg attattggtg taattacaaa aaacgagaat aacttaagta agcatttcta
     7681 aataattgag aaacctcatc taaaaagata agaaaatatc cctaataaaa cttctgtaac
     7741 attttagata actgattgta agctgaataa taaactataa ggagacagtt agacggtctc
     7801 ctttttttgc gtattataat tctagaattg ttggaaattg ataataatta acaagaaata
     7861 ttagacagga acttcgaact gcttatcaca ttcttattat tatatatttg cgtaagtagt
     7921 cctggtagtc tcaatgcact attctatctt gaaactaaga agttatagaa ggagcaatga
     7981 tagaaagcac gagaatacaa atagcgatta aatatttttc tagacaacct tagttaattc
     8041 acacagatat attttaggta cagtcttaca gatatagagt tagtgctgtg tgaatcctga
     8101 tgttcgcagt gcataggagt caagtaagat tctagccagt atagaaagtg gaagtctgga
     8161 gcgtacctca taatctggga agaaggagcc ttctgattta aagccaacaa aaggaatctc
     8221 gatatgttcc atcaaacttg aatgacgatt agcagtaagc aaaattgtcc cgatctcagc
     8281 tttataacag ttttcagctg cggtaatcaa ttcctttgtt tcaccgttta gtgaaacaaa
     8341 gatcacgatg tcatctttga ataattttct actaatgttt tttatgatat tgggatcagt
     8401 atgcatctca caatatttac cggtaagttg aaatttgacc atcatttcct gagcaatcaa
     8461 ttctgaaaaa cctcgggcaa aaatcatgat tcttctagca gccttgattc gttgaatagc
     8521 atcttcaata ttcccgcttt ctaccatatt gatggtgcgg attacctctt gctcattttt
     8581 aagaatagca gtctttattc cttcatcaac tttatcaaga gcggcaaaat tgatatttgt
     8641 attttctttt tcttttaacg aatgtttaaa agacgtaaac ccctcatatc cttttttctt
     8701 catagtacga acgacggttg ctgttgaaac gttggcatat tcacttagtt ttacaatgga
     8761 ataggagggg atttcgagta tgtgactttg aataaaatcc cagagatatt tctccgattc
     8821 acttaatttt gtatccatat tttgcctccg attagttagg ataattctat tgtaaagcgg
     8881 gagtttcctt tacttcaagt ttatttaata tattttgtaa aagttttcaa tgaatttagt
     8941 catttatgaa aacatttaca ttcgatcttg atacataatg aatatgtaag aaaggaggag
     9001 cgtaaatgtc agtttataca tgtactttaa acttggcaat cgaccttttt atcgaaacag
     9061 atgaaatgaa accatcccaa gtcaatcgaa caaacgatga tgatatacaa gctaatggaa
     9121 aaggggtgaa tgtttcattg atcatgaagc aattaggtat cgatagtaca gctttaggat
     9181 ttaaagcagg ttttaccggg aattatattg aggattattt gcatcaaaaa gatattagca
     9241 ctgattttat tagcgtaccg ggaatgacta gaatcaacgt ttttacacaa gttaataaaa
     9301 ccaatgaaga attcaaattg gttaataaag gacctgagat tcctcaggaa caaatcaaaa
     9361 cttttctaaa tcaaatacaa aagctgcaag ctgacgatta tttgtgtgtt tctggcagtt
     9421 tgccgcgagg ggtctcaccc gaaattctta ttgatatcag tcgtatttgt tttgaaaata
     9481 aggtccatct gattattgat tcaagctatc cggaaataat tgattgtctg ccgtatcagc
     9541 cgttcttatt aaaaccaaac gaggaggaat tgcaatcttg gtataatgtc gagcttagtg
     9601 atcgtgaagg atatattcat tatgctgaac gcttgattgc cgatggagcg aaaaatgttc
     9661 tcctttctct aggaggagag ggaggaatat ttttaaataa ggatatcgtt tattctggga
     9721 attctcctaa aggtaaagta gtcaatacag cgtgtgctgg tgacactttg ttgggaacat
     9781 ttcttgcagg atatttaaaa ggtgaacagg tagatattaa tttgaagaaa agtttagcag
     9841 ctggaagttc aaccgctttt cgtaaaggat taacagattt ttcggatgtt gcagagttgg
     9901 aaaaacaaat cgaaatcaaa gagggagcga gtaaaaaatg acaacttaca aaattgttgc
     9961 cgcaacagga tgtccaacag gaattgccca cacttatatg gctcaagaag cattggagca
    10021 ggcagctaag cgcaaagggg tatctatcaa agttgaaacc catggtcaag tagggataga
    10081 gaatgaatta acaccagaag aaataaaaaa cgctgacgct gtaatcattg cagctgacaa
    10141 agatgttcaa gcagaacgtt tcgcaggtaa gcgtgtaatc gatgtgcctg tcagcaaggg
    10201 gattaaagat gctgaccaat tgatcgaaga tgcgttggct ggtaaaggtt caatcattgc
    10261 agaaaacaaa acagttgacg ctgctggtga gaaagcggag atgggggttg cagcaggcat
    10321 tggtcacagt atttataaaa atctcatgaa cggtgtttct catatgctgc cgtttgtagt
    10381 ggcaggtggg gtaattattg caatttcgtt tgccatctgg ggtgtgtact cttttgatcc
    10441 caatgatcct acttacaatc cgactgccgc tatgttaaag ggtgttggtg atgcggcaat
    10501 gggaatgatg gttcctattt tagcagctta tatcgctgaa ggaatcgcta aacgtcctgg
    10561 tttggttgtt gggtttgttg gcggactgtt agccaattct ggcggagccg gtttcttagg
    10621 cggaattttt gcaggtttct tagcaggcta ctttatctta ctattgcaaa aggtcatgaa
    10681 aggcttgcct aaacaattgg atggtctgaa ggcgatcttc ttatatccgg tgatcggtgt
    10741 cttgtttgtt ggtgtagtca tgtctttatt agcaaatcca atggaagcag tcaaccaagg
    10801 aatgatgaat ttcttggcag gattccaaaa ttctaatcca ttaattttag ggattatcgt
    10861 tggctgtatg tcagcatttg atatgggagg tccagtcaat aaagcggctt atgttacagg
    10921 gactgcgttg ttggcacaag gtaaccatac atttatggca ggggtttcgg cagcttgtat
    10981 cgcgccccca ttgattactg gatttgccgt actgtttttt ggaaaatatt tcgacacgaa
    11041 tgatcgcaac gctggtttag tcaactttat cttgggctca acgcacatta ccgaaggagc
    11101 aattccattt gcggctaaag atccgctgcg tgttctgcca actatgatgc taggttcatc
    11161 aattgctgct gtactgacat atatgtttgg tgtccaagtt cccgcacctc atggaggttt
    11221 tctagtatta cctgttgtta ctggtaaggt tgcatgggta gggtcgattt tacttggttc
    11281 aatcgttggc ggagtaattt tagggttgat ccaaaaacgt agtgtagaaa aacgtgaagc
    11341 agaagcagct actgttgaaa tgaaagaaga aaccaacaac taaaggttat tctagaaaga
    11401 aggatttcaa atgactttga tcaaaacaaa taaagttttt atgaataaaa attttacgac
    11461 gcaagatgag gtaatgaact tccttgcaga tcagtcaatt gtcttgagca ttagtgaaga
    11521 ccgagatgca gtttacgaaa aattgatgga aagagaagaa gaaagcacga ctggtatgat
    11581 ggatggtttt gccatccctc atgccaaaga tgctagtatc aaggatgccg atattgtgat
    11641 tgttcggtta aacggtaagg tcgattggaa aagtttagat ggagaaggaa cggattttgt
    11701 aatcgctctg tttattccag attcagaggc tggaacaacc catctaaaat ttttatctca
    11761 ggtagccaga cttttgatgc acaaagatgt gacagaaggt ctgaaacaag cccagtctgc
    11821 tgaagaaata gctgaacttt taaaccaaaa attagaagaa aactaaaaag gaagtagtga
    11881 aatcatgcct ttaacagaaa aaaagaaaac ttatattcgt caactaagta atgaaagtgg
    11941 catcatcagt gcgttagcaa tcgatcaacg tggtgccttg aaaaaaatga tcggtaaatt
    12001 tcaaaatcaa tcagcaaccg atgaacaaat catcaatttc aaaaaaatca tttcttctga
    12061 attgactcca tatgcttcag caatcttatt agatccagaa tatgggttgc cggcagccga
    12121 agttcgcgat aaaaatgctg gtctgttgtt ggcctatgaa aaaactggtt acgatgcttc
    12181 aactccagga cgtttaccgg atattttatc tatttggtct gtaaaacgtc taaaggagca
    12241 aggggccgat gcttgtaagt tcttgttata ctacgatgta gatgaatctg atgatatcaa
    12301 tgaccaaaag aaggcgttta tggagcggat tggttctgaa tgtgttgctg aagatttgcc
    12361 atttttctta gaattggttt cttatgatgc caacgatcct gatacttctt cgaaggaata
    12421 tgccttgaaa aaaccgcata aagtaaatga aatgatgaag gaattttcta agcctcgcta
    12481 tggagttgac gttttgaaag tggaagttcc tgttaatatg aactatgtgg atggttacac
    12541 taaaaatgaa gttgcttata ccaaagaaga agctgctgct tatttcaaag aacaatccga
    12601 gactaccaac ctgccattta ttttcttgag cgcaggagta actgctgaat tgttccaaga
    12661 aaccttgaaa tttgcaaaag aggctggctc tacattcaat ggggtactct gtgggcgcgc
    12721 aacttgggcg aatggtgtag aaccattcgt tactaaaggt gaatatgctg ccaaagaatg
    12781 gatgcagaca caaggacgca agaacatcga agagctgaat aatgttttga aagaaacagc
    12841 aacagctatt aaattgtaag aaagctttaa ctataacctt aagtttgtaa cctaatgatt
    12901 tttaataatc aatttgagct tttaaataaa gaattggaag cgtcccgacg cttccttttt
    12961 cgtttgtctt aaggcatgat aggttctatg ttgtcgttca ataagcgcaa gaaggtcagc
    13021 atttttttct tagagtatgc aaaattgctt tctacccaat gatttaaaac ggagaggcac
    13081 ccttggatat ggtaaatggt gaagtaacgc atttcttctg tgatcacggt ttttttgtct
    13141 tcttgtagcc agatttttaa ataattttct tcgatcagat tatttaatct cttttggaat
    13201 tggatatctc cgtggttgat aacgaataac ttgtacacga acgtatttgt atagacatag
    13261 tcgatcaaat gagcgtatag atcctcgtag ctgtgtgtcg tgtcatagga aatgatttca
    13321 tccaagtctt agaaaaagct attttctagc ttttcataaa gatcatagat atccgtataa
    13381 tgtttataaa atgtcgaacg gtgaagatca gcagtttcgg tcagttcacg gatagtgatg
    13441 ttttgaattt ttcgcgaatt gtaaaattaa gttagaaaaa taaaaaggca tttatggtac
    13501 actcaaattg tatttccgac gaaagaaaac aaaggagtgt aaccataaat gacctacaag
    13561 gttctgttgc aaagttttaa ataaagaata aaatccctta cggtatctat gatttaagct
    13621 gggattccca ataatacctt gatttcagta cagaccgaaa acccgaagag agtgccttct
    13681 tttcgggttt tcttatataa tcctcgaatg gcttccatgc ctttaatcgt ggtagagcca
    13741 gtgcgtaaac ttcgatagaa tttattgcgt ctctttactg gacgatggtc ttgttcaatc
    13801 aaattattca ggtatttaat ggtacgatgt tctgtccctt gataaaagcc gccgtattct
    13861 tttagtttct taaaggcact tgtaatagag ggggctttat ctgtgactac aaccttcggt
    13921 tcatcaaact gcttcactaa ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt
    13981 ttacgtaacc aaatatccaa ggttaaacca tctgcatcga tggctcgata caaataatgc
    14041 cat
//
LOCUS       DADVXB010000070        13725 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.071, whole genome shotgun sequence.
ACCESSION   DADVXB010000070 DADVXB010000000
VERSION     DADVXB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.071"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(79..2076)
                     /gene="tkt"
                     /locus_tag="KB902_001654"
     CDS             complement(79..2076)
                     /gene="tkt"
                     /locus_tag="KB902_001654"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBB6808482.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAED
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2178..2429)
                     /locus_tag="KB902_001655"
     CDS             complement(2178..2429)
                     /locus_tag="KB902_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBB6808483.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2576..3199
                     /gene="lexA"
                     /locus_tag="KB902_001656"
     CDS             2576..3199
                     /gene="lexA"
                     /locus_tag="KB902_001656"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBB6808484.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3379..3597
                     /locus_tag="KB902_001657"
     CDS             3379..3597
                     /locus_tag="KB902_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808485.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3886..4398)
                     /locus_tag="KB902_001658"
     CDS             complement(3886..4398)
                     /locus_tag="KB902_001658"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6808486.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4412..6709)
                     /gene="recJ"
                     /locus_tag="KB902_001659"
     CDS             complement(4412..6709)
                     /gene="recJ"
                     /locus_tag="KB902_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBB6808487.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6851..7294)
                     /locus_tag="KB902_001660"
     CDS             complement(6851..7294)
                     /locus_tag="KB902_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBB6808488.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7295..8083)
                     /locus_tag="KB902_001661"
     CDS             complement(7295..8083)
                     /locus_tag="KB902_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6808489.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8080..9021)
                     /locus_tag="KB902_001662"
     CDS             complement(8080..9021)
                     /locus_tag="KB902_001662"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBB6808490.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9198..9785)
                     /locus_tag="KB902_001663"
     CDS             complement(9198..9785)
                     /locus_tag="KB902_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBB6808491.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10006..11313)
                     /gene="obgE"
                     /locus_tag="KB902_001664"
     CDS             complement(10006..11313)
                     /gene="obgE"
                     /locus_tag="KB902_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBB6808492.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11607..12617
                     /gene="gap"
                     /locus_tag="KB902_001665"
     CDS             11607..12617
                     /gene="gap"
                     /locus_tag="KB902_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6808493.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12702..13637)
                     /locus_tag="KB902_001666"
     CDS             complement(12702..13637)
                     /locus_tag="KB902_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6808494.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3771 a         3083 c         2423 g         4448 t
ORIGIN      
        1 ttattcttct aacacataaa gaacagctgt ctccaacttg cagacagctg ttcttatcag
       61 tcaaacaatt gcttggatct atgatagttg attgtacgta ttcacgacat tttctactgt
      121 aaatccaaat tcttctaaaa ttttagtgcc aggggcagat gcaccgaaat gatcgattgt
      181 aatcgttgcg ccctctgttc ctacgtagcg ttcccatcca aatgatgcag cagcttcgat
      241 agccacacgt ttcttcactg atttaggaag tacactttct ttatattcag aagattgttt
      301 ttcaaagagg tcaaagcttg gcatagaaac aacagaaaca tctttgcctt tttcagccaa
      361 ttctttttga gctttcacag ccaaatcaac ttcagaacct gttgcaatca aaataccttc
      421 tggtgtttct ccttgtgatg gagaaagaac atacgcgcct tttttcacca tttcatctgc
      481 tacttctttt gtagaaggca atactggaag gttttgacga ctcaatacaa ggatagtagg
      541 cgcatctgtt gtctccatcg ctactttcca agcagcacgt gtttcatttc cgtctgccgg
      601 acgaatcact tgaacaccag gcatgcagcg aacagatgct agttgttcaa tcggttcgtg
      661 cgttggtccg tcttctccga cagcaaccga gtcatgtgtt aagacgtaaa caacaggagt
      721 atgttggatt gctgctaaac gaactgctgg tcttagataa tcgacaaaga caaagaatgt
      781 tccaccgtag atacgagttc cgccatgaag ttggatacca ttcatagccg aagccattgc
      841 aaattcgcgg acaccgaacc agatgttgcg tccttcataa tgttcaggag tgaaatcttt
      901 atcttcagcc accattgtat tattggaacc tgacaagtcc gctgaaccac cccagaagct
      961 tggtatagct ttcgataatt cttggatgac ttctttactt gaaacacggc ttgcttgact
     1021 gcttccaact tcataagttg gcaattctgc atcccagttt tctggtagtt tgccatcaaa
     1081 agcatcttca aattgttgtg ctaattcagg ataagctttt ttataattgg caaacatttc
     1141 attccatgca tcttcagctt tttgtccttc ttctatcatc gtttgatgga agcgggcagc
     1201 tacttcttct ggaacagtga aatctggata ctcccaacca taaacttctt tagccatctt
     1261 gatgccatct tcaccaagag gagcaccatg aacagcagat gttccttctt taggagcacc
     1321 atagccgatg actgttttta cttcgatcaa tgttggtttg tctgtttcag cttttgcttc
     1381 ttcaatcgct ttagagattg cttctaggtc atttccgtct ttcactaaga tatgttgcca
     1441 gccatatgct tcatagcgag caccaacgtt ttctgtgaaa gcttttgaag ttggaccgtc
     1501 tagtgaaata tcgtttgaat cgtataaaac gatcaatttc cctagtttca tatgacctgc
     1561 catcgaactt gcttcttgag ataccccttc catcaagtct ccgtcaccgc atattgcata
     1621 cgtatagtga tccatcacat taaagttttc tttgttatac gttgctgcaa ggtgcgcttc
     1681 tgccattgcc ataccgacag ccattgcaat cccttgtcct aatggccctg tagtggcttc
     1741 tacaccatct gtatgatgta cttcaggatg tcctggtgtt ttagaatccc attgacggaa
     1801 ttgtttcaaa tcatcgattg tcacttgata gccagctaaa tgaagcaagc tatacaacat
     1861 tgctgaccca tgtcctgccg aaagaacgaa acggtcgcgg tcagcccagt tttttgatgt
     1921 cgttggattt actttcaggt gttttgtcca taacgcatat gccataggtg ctgcgcccat
     1981 cggcaatcca ggatgtcctg agtttgcttt ttggactgct tcaatactta atgtacgaat
     2041 tgtgttaacg ccaagttggt caattttgtc aaacaaaata acccctccta ttaatttagg
     2101 ttttttttac ctttatttct tacactttca ttctataaga tgtcacacga aaaagcaatc
     2161 tttttcagta ttttttacta aaagttgtca tttcggttgt gtaagccttt tttcttttgg
     2221 atttctttta atttttccgg ggtcacgtca ttgccctcag gatcgacgac tttcattcct
     2281 tcgatatgat gacgcatacc ggaacgaaaa gcttccaaat actctttgcg caagttgatt
     2341 tgttcttgtt cttcggcttt tgagagacca ttttccttct ttttacgtgc aagttcattg
     2401 atccgctcta ttttttcagg tgacagcatg ctcagccctc cttttactct ccttcatatt
     2461 atataaaaac tgaaaaaaaa acaactagat aaactaaata aaatacgaac attcgtttga
     2521 tttagcgctt tttatatggt actatttatt tatcaagtga aagaaggtgt accttgtggc
     2581 ccgacaaact gaatcaagac aaatcgaagt cttacgatat atccatgaac aagtaaccca
     2641 aaaaggatac ccgccgactg tccgtgaaat cggggaagct gttcagcttt cttctacttc
     2701 tactgttcac ggtcatcttg cacggcttga aaaaaaaggg tttatccaaa gagatccgac
     2761 gaaacctcgt gcaatcgagt tgacaaaaca aggtttagaa aagattggga ttcgtccaac
     2821 aactattcca gtacttggcg tcgtaacagc tggagaaccc attttagcag tagaggatgc
     2881 ttcagacttc tttccaatcc ctcctaatct ttcttccgaa gaaggcagtc tctttatgct
     2941 gacaattcgt ggagatagta tgatcaatgc tgggatattg gatggtgaca acgtgatcgt
     3001 tcggaagcaa gaaactgctc aaaatggcga tattgtcatt gcaatgactg ccgaggacga
     3061 agcgacttgc aaacgattct ataaagaaaa aaactttttc cgtctgcagc ctgaaaacga
     3121 cttgctcgaa ccaatcatct tagatcaagt atctatatta ggacgagtag taggacttta
     3181 tcgtagtcat atctattaat tgctactaat taaaagaaaa ctttttaaaa agagtttgag
     3241 acgttggtct caaactcttt tttcgcccgg gttcttcttc tttcaaattt ttatcacttc
     3301 cctctttaca aaccgaacaa atattcgtat actaaatata cgaacaattg ttcgcataaa
     3361 ttaaagaggt gagaattcat gaaatcaatg agacgtcttg gcttagtatt aactgttttg
     3421 tttttaggta ttattattgg taatttcggc atacgtccag ctttacttgt gtttgttccg
     3481 ttatttactt tgtggttcat gttgtgggat gaaaagaagt accgtcaatc tgagcggcgc
     3541 agaattcatg aagatcattt ctatcatgag ccctactaca gatccaggca atcataataa
     3601 ggattgactg ctaattattc aaaagacaag aagttaaact tttacggggg tgtgacaaaa
     3661 atcggtcaca tccttttttt cgaataaacg gtgttctaaa gccagttttt cggtattaag
     3721 tcaaattgcg gaaaaagtga ttttttaaac ttctactggt ctttgcttgt ttccatttat
     3781 aaaaaaatag cgaccctcaa aagtcagata gagaatctga cttttgaggg tcgctttaaa
     3841 atcgcttctt taagaatatc atcaagaata gcttcttttt tctgcttaat attccattaa
     3901 tgtaatgatg tcatatcctt tgattttgtc gcgtccatgg agatccatca attcgatcaa
     3961 aaatgcgcag cctacgacta caccgcctaa ttgttcgatc agttcgatcg tcgctttgat
     4021 tgttcctcca gtagctagca aatcgtcaca aatcagcaca cgttgacctg gtttaatggc
     4081 atccttatgc aatgtcaatg tatctgttcc atattctaat ccataagtca cttcgatggt
     4141 ttctcgaggt aacttccctt ttttgcggac tggggcaaaa ccgactccta actcataagc
     4201 aacaggacat cctacgatga atccacgggc ttctggccca actaccatat caattcgttt
     4261 ttcttttgca taatttacga tttgtttagt agcttcccga taagcgtcac catctgccat
     4321 cagtggggaa atatctcgaa acacaattcc ttttgacgga tagtcgggaa tactggcaat
     4381 ataatctttt aaatccactc tttgtttcct cctaggttgt taaccatttc tttatggtag
     4441 gaatatcgct caaaagcaaa aattcctcaa ctttgatttt attgagccgt cgctggtata
     4501 atctgctctc agtcaaagga tgactttctg ggctagcgac tttttgtaaa acaccgttct
     4561 ctattgtaac aaatttcaat tcaaaaaaca cctgtatcat aaaaattaat aatttttcag
     4621 ggatacgcaa atattgagct attgctttta ttttatgacg tatatcaatt cgttcttgag
     4681 aatggatcaa tttaaacaat tttgcgtact gttctcttgt gcctacccca ttcaaatagg
     4741 cctcatcagg tgaaatcccc atcagataaa cacgattgaa tgaataagac cgaaaaactt
     4801 ctttcagatc cgctaaatca tctggacaat ccataacaac tagagagttt ggttttcttt
     4861 tttcaattat tgcctttaca gaatctagtc cttcgaaaac aatcgcagct tcctggataa
     4921 tctcaggcac gaatttcaac gtcgaagaat caaatgctaa ataaaggcta ccttccgacg
     4981 ttcggctctg ttcacggaaa cgttttgccc gccaatcaaa tacttgcaga ccacccacag
     5041 aaaaatcaga taccatcagc tgcggtttct tacgcccgtt ccattcattg atcgaaagct
     5101 ttcctaccac atctacctga ttattcagca gttcttcttc ttgagtacca aaaccaaaag
     5161 cgaccgcatc aagctgactc gatgcatcgg aaaggacaaa tttcagatgc tgttggtttg
     5221 ctccgattct tttgatattt tctgcttgga cttgtcgaaa taaaaactga ggcaaaggat
     5281 tatccgtacc aaatggcgcc aatagtttca gctcatcaat tcgctctact gttacttcat
     5341 ttggcagcaa tacttcatca attctcaact caggccctct catcaagtca atttgatgat
     5401 cgactatata ttggttcatc ttctcctgta gtatagtgac attttcactt ggcatcgtta
     5461 aaccgactgc tgcatgatgt cctccgaagt aagtaaataa atctcgcatc tggtcaagca
     5521 tttcaaaaag attcaaggct tcaatactac gtccagatcc tttagctgat ccatcttctt
     5581 ttaaagtaag gacaagcgtt ggtttacccg tttcattcat tattttccca gcaacaatgc
     5641 ccaaaacgcc ttcatgccat cctcggttta ccaatagatg gatatgattc tccttattga
     5701 ccatcgctaa tgcttcttgt gttatctgct ctacgattgc ttttctttct tcattgatct
     5761 cattcaattt ttttgcttga acggatgctt cctcttcatc aaacgtcgca agtaacgaga
     5821 cggcaggacg tggatcgccc atccgaccga ttgcatttag tctgggagca atcgaaaaac
     5881 cgatcgttgt ttcgtctgcg tccctcattt ttacgccgct ttcttcaaat agcgcctgaa
     5941 gtcctatccg ttctgaatga tgaatggcat cgattcctaa tgaaacaagg attcgattct
     6001 catcagtcaa tgaaactaaa tcggcgatcg ttcctatcgc tactaaatcc aaaaattctg
     6061 caggcggttc ttccaataat gcagaagcta ctttgaatgc tactccgact cctgccaaat
     6121 ctggaaatgg atagtgcccc gctggatgac gagggtgaac aatcgcataa gcgtctggta
     6181 aattctcagg tagttcgtga tgatctgtaa tgatcacgtc tacaccagct tgctgagcgt
     6241 atgctaccgc atcatttcct gctaccccgt tatcaacagt gatgatcaac tggattcctt
     6301 cttcgatctt ttcttggtat accgattggt ttggtccata cccatgctca aatcgatttg
     6361 gcaggaatac ttctacttct gcaccaagta attccagtgt ttctttcatt accgttgcac
     6421 tggtgatccc atctgcgtca taatcaccgt aaacgaggat tttttctcca ctgattacag
     6481 cttcttggat tcggctgatt gctttatcca tatcgtgtat cagatacgga tcatgtaatt
     6541 cttgttcctt tggatgtaaa aatcggttga tatccttttc ctcatggtaa cctctttgcc
     6601 acagtaactt accgacaaat ggagataatt tcagttcacg gatcatttgg agaaaggatt
     6661 cagaaggctc tgtctcgctt aacttccaat caaaatttgc ttgtctcact ttctcactcc
     6721 taacttagtt attatagcaa aggaaatcag caaaaaaaag cagaaagaaa gaataaaaac
     6781 agatcagatc cgctagacag atgttcagca ggacctgatc ttttgtacga ccatttatga
     6841 aatatcccta ttagtcaaaa taattgaagc tttgtttggg cgattgagtt ttttgttctt
     6901 ccggcgcttt caattgactg atttgtgcgg ttttcgcttg taactccgcc tgataagcag
     6961 cttccaactc cgcacgttcg tttctaaact cgcgttgctg ttcttctttt gcttcttcaa
     7021 ttttcttttg aagttctgtt tgatattctg acatttcctg agtcagctgt ttgatttgct
     7081 ttttttgctg ccatagtgtt gccgaagcag tcaaaaatac aatcagtgca ccaatcagcg
     7141 cagaaccgat gatcactaag atcaatggcg cagaaaagga agtgaagcca aaacttacag
     7201 gaacattttt attgttcaat acagcaaaaa gaacaataat caaaactaaa acaaatccaa
     7261 gaatcacatt gctttgcttt ttcaattcct tcacctactt tttgttaaaa attccgctgg
     7321 ctaaataatc accaatcgtt ggaaacagcg tataaaattt tgatgcaact tctaaaataa
     7381 acggttgatt gatttcccgt tttggatgtc tcatattgcg gacgatcatt tttgccaact
     7441 tggcaggttc taaaacgatt tgtccgactt tttccaaata gcttccgctt ggatcagcct
     7501 tatcgaagaa atttgtctcg attggacctg gattcactgt cgtaacagct acgccaagtg
     7561 gtttcaattc taatcgcaaa gcgttggaga agccaaggac tgcaaatttc gtggcagaat
     7621 aaaccgttga ttttgcagtt gccatttttc cagccataga ggcgatatta atgatatgac
     7681 cttgtcttct ttctgccata tcgatcgcaa atttttgtgt caaaaccatc attcctaaga
     7741 tgttgacttc aaacatatcg tatgcttttc caaggtcgaa tgtaaggaag tcttcgaaaa
     7801 tcccaaaacc cgcattgttt accagaatat cgacgcgccc gacttcttcc atcacctttt
     7861 catataattc gtccacgctt tcaggattgc tgacgtctac cttgaaagca taagcctctt
     7921 tgccgctcaa gcgtctgcac tcgtctctga caccttctac aaatgccatt cttcgtgcgc
     7981 aacttataac gattgctcct tgctttgctg cttcataaca gatttgtgcg cccagaccgc
     8041 ctgaactacc tgttactaaa acaactttat cttctaaatt catgcctctt cctcctcgcg
     8101 aaatggaatc tcaatgctat caaaatcttt cataatcgtc gtgttttcaa acacttcttg
     8161 tgcttctttt tcaagctcta aagctgcttt tcctaaatat ctcgcactga tatgagtaag
     8221 tagcagccgt tttgcctgcg cttcttttgc aacttcagca gcttgatgag tcgtggaatg
     8281 gaaatagttg tgcgccattc ttgcttcatc tttattaaat gtgctttcat gtaccagaat
     8341 atcgctattt tccgcaagca caacggaatt atgtgttttt ctcgtatcgc ctaaaatagt
     8401 cacgattcgt ccttttttat ctggacctac gaaatctttt ccattgatcg tccgcccatc
     8461 ttctagttgg atcgtttcac cttgcttcag tttgccgtac agtggtccag ctggaatacc
     8521 taattctttt agacgatcca cctgcaattc tcctttatga tcatgttcaa ccacacgata
     8581 accaaaactg tcgatcccat gatttagttt ttttgtataa acagaaaatt gctgatcagt
     8641 aaaaatcggg gctgtttcat ttagctcaat gaatttcagc ggataactta aacgcgtttg
     8701 cgaaatacct aaagagactt ttatgtattc ctctatccct tttggcccgt aaatctctaa
     8761 tggcgtatcc ccaccttgaa atgaccggct gctgatgagc ccgggaagtc caaaaatatg
     8821 atcgccgtgt aaatgtgtaa tgaaaatttt accgattttt ctcggacgaa tagtcgttcg
     8881 caaaatctgc atttgcgtgc cttcgccaca gtcgaacaac caaacttcat tgcgctcgtc
     8941 taaaagtttc aatgctatac ttgtcacatt tctatgtttt gcaggaacac ctgcacctgt
     9001 tcctaaaaat tgtaattcca taatctacct gactttcttt aagttcctct ttaattttag
     9061 ggtaaaaaga agggataatc aaccgtaagt cgagaatggg ttcaaattaa aaataacgtt
     9121 ctaaagcgat agcgttttct ttgaaaatta ctataaaaac agcagcgaac ccgtttgaga
     9181 tcctctgctg ttttttatta atttgaagat ccagaacttt cattgtcgtt ggaagtttgc
     9241 ggatgtttgt ccttccaagt cttttgtgca gcttctttcg catgattttc agcttctttc
     9301 gcatcatgca catctttttc gacatcttca taatccaagc gagtaatttc tccgcctaat
     9361 tccatcatta ccaattgatt cagtgggcga ttgtcctctt catcagcaat caagatcagt
     9421 cctgtagctc cttcaccgat tttatttcct acaaagtcga acacggtctg ggcatctttt
     9481 atttctttgg catcttgtgt cgcaccgatc attcctccgg caaaccatcc taataaaatc
     9541 cctagcggac cacctaatac accaaccaac attccgatta atccacccgt agaagatttg
     9601 ttattaccgg taaagtcgat aaaatcttct attttgaatt gatgtgtccc attaggatca
     9661 tggctgacaa ctgccatctg ttctccttta atcgaacgaa cagcatgtaa ctttttgatt
     9721 tctgaaaatg cctgatatgc ctggctttct acttgaaaat ttaaaatgat tactcgtttg
     9781 ctcattaaaa acgccccttt cataccttct tgttatttat tttaccttta attgtaaaat
     9841 aagaaaagaa aagcactctt tttttccaat aaaatagggc tgtgacaaaa gtcgtatcac
     9901 agctcctttt tccgaataaa cggcgttctt gaagctgatc acttctgtca caacctccct
     9961 taaatctgaa tctatatttt ttggtatttg tttttatttg cttgcctatt cgacaaattc
    10021 aaattcaaac tcaccgatac gtacaaggtc gccatctttc gcaccgcgtg cccgaagagc
    10081 ttcatccaca cccataccac gtaattgacg agcaaaacgc atcactgttt catcatgatc
    10141 gaaattcgtc atttggaata atttttcgat cttctcacca gataagatcc acgttgcatc
    10201 tgaatcacga tcgatttgga actcaggacc ttctggattg aatccatagt gtacagtttc
    10261 ttcttccagt tcttcttcgt acaatgggaa ttctggcgtt acttctaaca aatctgctgt
    10321 agcattcaat aacgcgtcca atccttgtcg agtcactcca gaaattggaa atactgggat
    10381 gtcatcagca aattcatctt ctttttcctt gttcagctgt tctttgaatt tcactagatt
    10441 ttccggtgca tccggcatat ccattttgtt tgccacgatg atttgcggac gctctagcaa
    10501 gcgtaagtta taagtagata attctttgtt gatggcaaga tagtcttcat aaggatctcg
    10561 tccttccatc ccactcatat cgatcacatg taaaattact cgtgttcttt cgatatgacg
    10621 aaggaattgt gtacccagcc caacaccttg cgaagctcct tcaatcaagc ctggcaagtc
    10681 tgctgcggca aaacttctgc catcacttgt agtaaccatt cctagattag gtacgagcgt
    10741 cgtgaaatga taagcgccga tttttggacg agcagatgaa ataacggata gtaaagtcga
    10801 tttcccgaca gatggaaaac ctacaagtcc aacgtctgcc aatactttca attctagttc
    10861 gatttttcgc tcttgtcctg gttcaccgtt ttcagcaatt tccggtgcag gattccgagg
    10921 agaggcaaaa cggatattcc ctcgtccacc gcgtccacct tttgccacaa ctagtgtttg
    10981 accattttca attaaatctc ctaaaagagc accagtctcc gcatctcgga cagtggttcc
    11041 ttgtggtact ttaacatagg tatcttctga accacgaccg tgcatccctt tactcatccc
    11101 attttcacct ggctgcgctt tgaaatggcg attgaaccga aaatccatca atgtacgtaa
    11161 cccttcatcg acgatcaaga tgacatcgcc gccacgacca ccgtctccgc cagccggtcc
    11221 gccgtcagga acgtattttt cgcgacgaaa tgcaaccatt ccgtctccgc ccttgccagc
    11281 tttcacatcg atcgttactt gatctaaaaa catggacata attaagtcct cctattattc
    11341 atttatttat ttgactgcct gaatttccac aataaacaaa agtcttactt attttatcgg
    11401 tgaaatctga ttttgtctat catttcagca aaaagattgt ttaccttctt ctttttttat
    11461 catttggtaa ggtttccaac cttttttctg ctaccaagta taattttttg acaaaatatt
    11521 ctttgcgtag cagaataaca gtgtattaat tgtattaatt gaggatgccg tttcacagca
    11581 cccctaataa aggaggaact tttgatatga cagtaaaagt aggtattaac ggatttgggc
    11641 gtattggccg tctggctttc cgccgcatca aagaagtctc agatgatatt gaagtagtag
    11701 caatcaacga cttaacaagt ccaactatgt tagcacaatt attgcaattt gactctactc
    11761 atggtactta tcctggcaca gttactgcaa cagaagactc aatcgtagtg gatggcgaag
    11821 caactcgtgt ttatgcagaa cccgacgcaa gcaaaatccc ttgggcaaaa gaaaacggtg
    11881 tagatatcgt actagaatgt actggttttt atacatctga agaaaaagca aaagcgcatt
    11941 tagatgctgg tgtcaaacga gtagttattt ctgccccagc tggtgctatg aaaaccatcg
    12001 tctataacgt caatgatgat acattagatg aaaacgacaa aatcatctca gcaggttcat
    12061 gtacaacaaa ctgtttagca cctatggctt atttcttaaa taatgaattt gggatcgaag
    12121 ttggtacaat gacaacagtt catgcctaca cttccacaca aatgctctta gatggacctg
    12181 taaaaggcgg taatttgcgt gctgctcgtt cagctgctga caatactatc ccacattcta
    12241 ctggtgctgc gaaagcaatc ggcttagtta tccctgagct acaaggaaaa ttacaaggac
    12301 acgcacaacg tgttccagtc gttgatggtt cattaactga attggtttca gtattgaaaa
    12361 caaaagtaac tgctgatcaa gtaaacgaag caatcaaaaa acacacagtt gacaatcctt
    12421 cattcgggta tgatgaccgt caaatcgttt ctagcgatgt cattggaaca actcaaggtt
    12481 cgatctttga cccaacgcaa acagaagtaa caactgctgg tgatttccaa cttgttaaaa
    12541 ctgttgcatg gtatgacaat gagtatggat ttacttgcca aatgattcgc ttactagaaa
    12601 aattcgctaa cttgtaattt gatagatcaa tcgataaaag aagcctttga ctggatccag
    12661 tcaaaggctt ctttcttttc atcccctact tttaaactcg ttcaatgaac atattggctt
    12721 aaaaattgtt ggactacttg ctgatatttt tcaggatctg tcttgtatgc ttccgcatgc
    12781 tcggctcctt ttacaacata cttttctttt ggtcccttcg ttgcacgata gaccttatct
    12841 aacatttcaa atggtacaaa tgtatcttcg tctccatgta taaagagcat tgggcgctgg
    12901 tttttcttca attgttccac tgcatttgct tcaccgaaaa agtagccagc acggactttt
    12961 gtcactagac tcgttacttg cataagcgga aatgctggaa gactaaacat atcgtctagc
    13021 tgataagcaa gctcatcatg aacggaagaa taaccgcaat cttcaatgat tgctttcaca
    13081 ttatctggta gtttttctcc gctagtcatc ataactgttg ctgctcccat gctgacaccg
    13141 tatagaacga tttcttgcga ttttccattg ttttctagca ctttgtttat ccactgtaca
    13201 tagtctttac gctctggcca tccaaatcca atgtaatccc cttcgctttt tccatgtcct
    13261 cttgcatcag gaacaaggac attgtaaccc atatcatgaa acatctttgc gtaattggtc
    13321 atcgtttcag cgtttcccat atagccatga gccacaagag ctgttttttc acttttcgtt
    13381 tcagcaggaa gataaatcgc tgataatttc agaccgtctt ttgaagtgat ggtccaatcg
    13441 cttcggtttt cttttgaact aaaccattta tgtgcatccg tttctttgga tgtctgtgtt
    13501 gtaccaggtg tatcttcgtc taaaaagtct ttctcagaag gcacaacagc ataattataa
    13561 aaataattcc ctgcaaacac taacgcaaca atcagagcta aagcgacgcc taaaaggatt
    13621 ttcatccaaa gtttcataaa tcatccatct catttctctt ttttcatata accttgaatt
    13681 agtataatca aagaatctct actatgcaat gttcattttt ataac
//
LOCUS       DADVXB010000071        13701 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.072, whole genome shotgun sequence.
ACCESSION   DADVXB010000071 DADVXB010000000
VERSION     DADVXB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.072"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..897)
                     /locus_tag="KB902_001667"
     CDS             complement(<1..897)
                     /locus_tag="KB902_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBB6808495.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFS"
     regulatory      complement(921..965)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1180..2148
                     /locus_tag="KB902_001668"
     CDS             1180..2148
                     /locus_tag="KB902_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6808496.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2261..2539
                     /locus_tag="KB902_001669"
     CDS             2261..2539
                     /locus_tag="KB902_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6808497.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            2657..2893
                     /gene="secG"
                     /locus_tag="KB902_001670"
     CDS             2657..2893
                     /gene="secG"
                     /locus_tag="KB902_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBB6808498.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            2996..3751
                     /locus_tag="KB902_001671"
     CDS             2996..3751
                     /locus_tag="KB902_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6808499.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3754..6111
                     /gene="rnr"
                     /locus_tag="KB902_001672"
     CDS             3754..6111
                     /gene="rnr"
                     /locus_tag="KB902_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBB6808500.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6133..6597
                     /gene="smpB"
                     /locus_tag="KB902_001673"
     CDS             6133..6597
                     /gene="smpB"
                     /locus_tag="KB902_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBB6808501.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6899..7618
                     /gene="atpB"
                     /locus_tag="KB902_001674"
     CDS             6899..7618
                     /gene="atpB"
                     /locus_tag="KB902_001674"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBB6808502.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7671..7886
                     /gene="atpE"
                     /locus_tag="KB902_001675"
     CDS             7671..7886
                     /gene="atpE"
                     /locus_tag="KB902_001675"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBB6808503.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7977..8501
                     /gene="atpF"
                     /locus_tag="KB902_001676"
     CDS             7977..8501
                     /gene="atpF"
                     /locus_tag="KB902_001676"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBB6808504.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8488..9030
                     /locus_tag="KB902_001677"
     CDS             8488..9030
                     /locus_tag="KB902_001677"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBB6808505.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9053..10609
                     /locus_tag="KB902_001678"
     CDS             9053..10609
                     /locus_tag="KB902_001678"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBB6808506.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10623..11525
                     /locus_tag="KB902_001679"
     CDS             10623..11525
                     /locus_tag="KB902_001679"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBB6808507.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11548..12954
                     /gene="atpD"
                     /locus_tag="KB902_001680"
     CDS             11548..12954
                     /gene="atpD"
                     /locus_tag="KB902_001680"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBB6808508.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12968..13390
                     /locus_tag="KB902_001681"
     CDS             12968..13390
                     /locus_tag="KB902_001681"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBB6808509.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4528 a         2457 c         2986 g         3730 t
ORIGIN      
        1 ggaaaaaaga cgagtatcta cttttgtcat aattttactg ttagcaggtt tctgccaaaa
       61 ttcataacga tcaaccaatg tttgtccacg acttattccc tgagtttcca cagcggtgaa
      121 gcttttgaaa ccttcacaga tggccccctc gatgaaataa gcaacagcta acggatcatt
      181 gatgacacat cctaaaattc tttcttgttt ccagtggaag tcaaaataaa aacgagtgat
      241 cgcttttaaa tactctccct cttcaggatt catttgacag cagtattcga ggatagtcgg
      301 tgtcaagacg atttctcttg tcacatctaa cccaaccatt tctatcgttt gtttgagatt
      361 ctcgaataca taagaagctg cttcaggatc acaccagtaa ttgtattcag caactggcga
      421 acagttacca tggcttttgt aagttccacc catcgagaca aaacgatcca tatgtttccc
      481 aatatttggg ttgactttca aagcaaaagc gatattggtc aaaggaccca aagcaatgac
      541 tgatgtattt gtcttttctt tgaaataatc agccaaaaaa tcaacggcat ggagaggttc
      601 tgcctgtttt ctcaagatca tcgggaaatt tgtttcccct aaaccatcca taccatgagt
      661 gtcttgtgca ctgatgaaag gttgcttcaa aggtttttcc attccttgat aaacaggaat
      721 gtctaaacga tcacagcgtt ccaggcattt cagcacattc tgcgtaccta tatctgcagg
      781 gacattccca caaactacgg taatagcaac tacttcgata tcaggggatt tgacagctaa
      841 tgataaagct aaagtgtcgt cgatccctgg atcgcaatca ataattactt ttcgcattat
      901 ttccaatctc ctttctttag agatacttag ttttttattc tgggaagttt ccgaaccagt
      961 ccaagacgag cgtcttgatt ataatgcacg aaattagtat actggctttt attgcgaatg
     1021 taaatgctct cttacaagta aatctattga ggagaacttt aagtaaatga tacaatgaaa
     1081 aagaaatgga atttacgtgt gccgaaaata aagaatccta tggatcggta cattggataa
     1141 tagatagatt atagtttggc agaaagcggc gggtgtacaa tggttatttt ttatttcatt
     1201 cttattctga taattatagg gatcagttac cattttcttt cttattttta tgcaaagaaa
     1261 ttagtaagag cgggagtaca gagaggatat gactggtatg aagacactgg tcatcgtttg
     1321 atggaccctg ctgcagtcac gtcagtagaa aaaaaacgac aaaaattaga agaagagtgt
     1381 gaaagctttt gggagcaggg aacacccaaa acaatcaaaa gttatgacgg gttgaaacta
     1441 gctggtcaga tgttcatcca tccaaataag cagaataaat gggtcatttg cgtacatgat
     1501 taccgaagca cagggaaaag agacatgtct catataggta aaagatatgc agagaaagga
     1561 ttcaacgttc ttgtacctga tttacgtgcg cacggagaaa gtgaaggaga aatcatcgga
     1621 atgggatggc tagatcggct agatttaatt gcctggatcc aactcatctt agatgaacag
     1681 ccgaatgcgt ccattatttt acacggcgga tcaatgggag cttctacgat catgatggca
     1741 agtggtgaaa aacttccatc agcggtcaaa ggatttattt tagacagcgg atatgtttct
     1801 gtttatgcag aattccgata tatgttaagt aaaatcactg tctttcctaa aaaaatggtc
     1861 atgagatatg cgaatcatta tgcccagaaa tacgccggtt actccttaaa gcaagcatca
     1921 gctacgagac agcttggcag caaccatctg cctttattag tcatccatgg tgaaagagat
     1981 cattttgtcc ctacagaagc agcgtacacg attcaaaatg ctacggcagg ggataaagca
     2041 ctgctgcttg ttccagaagc agaacacttg gaagcatcga tgaaagatcc gaaaacctat
     2101 tggacagtga ttttttcatt tattgaacaa agaataacga tggattaatt ttctcttctt
     2161 ttttgtaagt aattcgagga taaataattg tttatagatc tggagactgc taaaataagg
     2221 taggaataaa aaaatatcag ttatttgagg agtgcggcat atggaaatca aagaagaaaa
     2281 aaatcgtctt gctttattca atgatgagca acaagaaatc ggagaaatga catggtcgga
     2341 tgcggggcca gacatcatga tcattgacca tacatttgtc gatccagcat atcgtggtca
     2401 aaaattagct gaaaagctag tgtatactgg agtagaacta gcaagacgag aggggaaaaa
     2461 gattatccct tcatgccctt acgcaaaaaa agagtttgag aagaaaccag agtatcatga
     2521 cgtcttacgc caatcataat aataacagct gaaagatttg cactttcagc tgtttttcca
     2581 tttatataga gttgtcacgg agttttatct atgataaagt taaagagacg atatcttttg
     2641 ggaaggaggc tgctatatgt ataatttaat tttgggaatc gtgatcgttt tatcgattgt
     2701 tatggtcatt gcgattatga tgcagccaag caagcaaaat agtgcagcga gtgcatttac
     2761 cggcggtgcg gatcaactat tcggcaaaca aaaagctcgc ggctttgaag ctgtcatgca
     2821 gcgatcaact gcagtcatgg gagctgtctg gatgatctta ttatttgtcc tagcattttt
     2881 atcttcgaag tagtcgaata agcctctcgc acaacggcgg gcggcttttt ttattgcaaa
     2941 gagaacgctt aagaagaagt tatgaaagaa actatggtaa aatgaggcga aagaggtgaa
     3001 acgagtgaaa caattaccaa aaccccttta tgcaaaacat ggaaaacgag cagttttgct
     3061 gcttcacgct tactcaggaa gtccaaacga tgttcgaatg ctcgcacgat ttttggaaaa
     3121 agcagattat acagtttatg cgccgctttt taaaggacac ggaacaatgg agccatatga
     3181 tatcttgcaa gaaaaagcag aaagctggtg ggcagacact aaaaaagcca tccatttttt
     3241 acagtctgag cagttttctg atattgccgt attaggatta tcaatgggcg gcatctttgc
     3301 tgtacgagca ctagaagaag aatcagtgat tggcggcggt tttttctgtt cgcctttgtc
     3361 tcctgtaaaa acaaacgtgc ctgaaaactt tgaaaaatac gtacgtcaag tgctgaagac
     3421 agcaggtaaa tcagagaaag aaatcaatga aaaagcagtt gcttaccgct cgttagctga
     3481 acaacaatta atggatatac aagatcaggc agcaatcgta gaaagtaggt tgtcagatat
     3541 ccaacagccg atatttttag ctcaagctgg gaaagatgaa atgatcgacc ctaatggcgt
     3601 atttgaaact gcacgcaagt tgagccgtca gcgagtgaca cttcaatggt atcctgaaag
     3661 tggtcatgtg attacagttg gtacagcaag acgcgaatta gaaaaagacg tcttggaatt
     3721 tttagaaaaa ttaccttgga atgaggaata aatatgacaa aagaaacgat aaaagagaaa
     3781 attctctttt tcatggaaag cagtcgcaaa cgcagttttt ctatggaaga aatcgctgaa
     3841 ggtttagggt tccaaaaaag cgatgatttt aaattactag tacaaacgat tgctcaaatg
     3901 gaaagagaac agagtatagt tttcaataaa aaaggaaaag tgaaacttcc tttaaaacca
     3961 atcttgatcg aaggaacatt tcgagcaaat gaacgaggat ttggatttgt aacgattgat
     4021 cccgaagaag atgacatcta tatcccaaaa gaagcgactg gttttgcaat ggatggagac
     4081 accgtagcaa tcgatatcat gaagcgagca aatacagata tggatcgcgg agcagagggg
     4141 aaagtagtcg agattcgaga ccgggcgact actcagttag caggggaatt cgttgcttat
     4201 tcagaagaag aaatacaaga aacagatctt tacggcgttg ttatcccgaa agatagaaag
     4261 ctcaaccaat ttaaagtata tgcagcagca gagggagttc gtccagttga cggaagtatt
     4321 gtgctgatcg aactgaccca ttaccctgaa aaagggtatg cgactagttt agaagggata
     4381 atcaagcaag tgattggtca taagaatgac cctggcatgg atatcctctc aattgtcgtg
     4441 gctaatggta tccctacgaa atttcctgat gatgtattgt ctgaagcaga tgaagttcca
     4501 gatcaaatca gcgaaaagga tataactgga cgtagagatt taagaaatca gctcattgtt
     4561 acgattgatg gagaagatgc aaaagatcta gatgatgcag ttacggttaa aaaattagat
     4621 aacggtaatt attttcttgg agtacacatt gcagatgttt cttactatgt gacacaaggc
     4681 agtcaattgg acagagaagc atatgaaaga gggacaagtg tatatttgac tgatcgagtg
     4741 attccgatga tcccgcaacg tttatcgaat ggtatctgtt cactgaatcc ccatgttcca
     4801 aggctgacca tgagttgcga aatggagatt gatccaaatg gacaagtagt ctctcatgat
     4861 attttcccaa gtgtgatcca aacaacagaa cggatgacct acacagctgt caatcaaatc
     4921 ttagaagatc aagacgaaga aacgatgcaa cgctatgctc agctcgtacc tatgttccaa
     4981 gaaatgggtg aattgcatcg aatccttgaa acgatgcgaa tcaaacgtgg cgcgatttct
     5041 tttgaggatc gcgaagcgaa aatccttgtt gatgctgaag gacacccaaa tgacatccag
     5101 ctaagaagca gaggaattgg tgaacgcttg atcgaatctt tcatgcttgc ggccaatgaa
     5161 acggtagctg aacattataa taaattaaat ctgccgttta tttaccgaat ccatgaacag
     5221 ccaaaagaag aaaaaatgca gcgcttcttt gattttgctt cagctttggg cattctggtc
     5281 cgaggaacga aaggaacgat cacaccaaaa gatttacagc atgtgatcga aggagtagaa
     5341 gacaaaccag aagctgcagt tatcaatact atgttgctaa gaagcatgca acaagcacgc
     5401 tattcagaag acaattttgg gcattatggc ttagcggcag attactacac acactttaca
     5461 tctcctattc gacgctatcc cgatctaatc gtccatcgtc tgatccgttc ttacagtgaa
     5521 gataaaagtg aaagcaatca aagttcgtgg gctgcggaac ttcctgaaat tgcagatcat
     5581 agttctaaga tggaacgtcg tgcagtagaa acagaacgtg aagtagattc catgaagaaa
     5641 gcagaattca tgatggacaa agtgggagaa gaattcgatg ggatcatcag ctctgttgtg
     5701 aaattcggcc tgtttatcga actgccgaat acagtagaag gattgatcca tatcaatgaa
     5761 ttgaaacagg actacttcca ttttgttgaa aatcatttag ctcttgtagg tgaaagaact
     5821 ggtctgactt ttaaaatcgg acaaaaagtg cgcgtaaaag tagtcaaagc tgatccagat
     5881 gaacgagcag tggattttga actcgtttcc gcagaagagg tcactgcgtt ggaacgtcca
     5941 aaagcacgca atggaaaatt tggaaaacga gaaggaaaac aagcaggcaa acgctcagaa
     6001 aaaaatggca agaagaacaa acgatatagt gatagtaagc aaacgttcgg taagaaaaaa
     6061 gggaaaaagc cattttacaa agatgtcaaa aagaagaaaa agaaaaaata aaatgagttg
     6121 gaggaaacag ctatgccaaa aggcgaggga aaactaattg cacaaaacaa gaaagctcgc
     6181 catgattatt cgatcatcga cacgatggaa gcagggatgg tcttgcaagg aacggagatc
     6241 aagtcgatac gaaacagccg gatcaatctg aaagatggat ttattcgcgt ccgcaacggg
     6301 gaagctttct tgcataatgt tcatatcagt ccttatgaac aaggaaatat ttttaatcat
     6361 gatccgttgc gcacgagaaa gttattatta cacaagaaac aaatcgttcg tcttgaaaac
     6421 gaattgaaaa acactggaat cactgttgtt cctttaaaag tctatattcg taacggctat
     6481 gccaaggtat tgattggtct ggcaaaaggg aaaaaatcgt atgataaacg ggaagatttg
     6541 aaacgaaaag atatcgatcg acaaattgat cgaacattaa aaaatttctc tagataattt
     6601 cattatcctt tttcgcatat tcggtgcttt tgcttttact taatgataaa atttgttagc
     6661 atttaatctg ataaaacatg attatcacag gttttttctt agatcaggag caccgtgcat
     6721 ggggaaaaat tcgcttcgtt tttgactgaa ataaaaaagt gtctaatttt catgaaaatg
     6781 ttttgaattt tctgtttcat ggtggtatga taccgtgtgg ttagaaaccg attggaaaaa
     6841 accagatacg cacatgaatt gattttatgt gaatttcggg gaaaagaggt gaaatggatt
     6901 ggatgaacgc tcgctaacgt ttcacattgg accaatttgg tttgatggta cagtttgtat
     6961 aatggtgtta ctgacctgtt tgattgtttt cttcttagct tactttttta caagaaatct
     7021 taagttgaaa ccaacaggca aacaaaatgc gatagaatgg gtcattgatt ttagtcgagg
     7081 aatcgtaaca gataatctgc ctagaaaaga attgagcaat ttccatttgt tggcatttac
     7141 attgttttta tttgtttttg ttgcaaacaa cataggttta gtaacaaaaa tcgtcttacc
     7201 taacgaaaca acactttgga aaagcccgac agcagacccg tttgttactt taactttggc
     7261 atttataatg atcttactta ctcacttatt cggggtgaaa aagttaggct tcaaaggata
     7321 tttcgtaaat tcgttcttga aaccctatag ttttatgttt ccgatgaaac tgattgaaga
     7381 atttacaaat ttattaacac ttgctttacg tctttatggg aatatttatg cgggggaagt
     7441 tttgctaacc ttgattgcaa aaatgatgac aagcttaggc tggttctcat taccattagc
     7501 aattccatta gagatggtct ggatcgcgtt ctccttgttt attgggagca tccaagcatt
     7561 tgtctttgtc actttgtcaa tggtttatat gagccataag attgaagtag aagaataata
     7621 ctcggttaaa aaacaaacta ctatttatct attttaggag gaaaacaatt atgaattata
     7681 tcgcagcagc aatcgcaatc atgggagcag caatcggagc cggttatggt aacggtcaag
     7741 ttatctctaa aacaatcgaa tcaatggctc gccaacctga aatgtctggt caattccgta
     7801 caacaatgtt tatcggggta gctctagttg aagctgttcc tatcttaggg gtagttatcg
     7861 ccttgattct agtttttgcc gtttaattga atcagtatta aggcagaaac aacatcgttt
     7921 gttactgctt ttttacatgg aaactagaaa tactccaaag aaaggaaggc tcgcctatgc
     7981 tgaatcaatt ggcaattgca gaagttggca atgcgatgtt aggtaatatc atcgttgtca
     8041 gcggctcatt tttgatacta ctggctctct tgaagcactt tgcttgggga ccaatcagcg
     8101 atattttgaa aaaacgtgaa gacaagatcg ccaatgattt agattctgca gaacaatctc
     8161 gcatcaactc agcgaaaatg gaacaagaac gcgaacaaca attgttagcc tctcgttctg
     8221 atgcagctga tatcatcaaa aatgcgaaag aaagtggaga attaagccgc caaaatattt
     8281 tgaaggatgc tcaagaagaa gcagctcgtc taaaaagcaa agcccaagct gatatcactg
     8341 tagaacgtga ttcagcgctg aactctgtaa aagacgacgt tgcagaactc tctcttcaaa
     8401 tcgcggaaaa aatcttgaac aaagaattat ctccagaaat gcatgaatca ttaatcaatc
     8461 aatacattga aggtctaggt tcttcaaatg aaactagata aatatacagt aggaagacgt
     8521 tacgggaaag ctttatttga actggcgatc gattcaaatc aagcagaaga aatctatcaa
     8581 gatctcgtaa gtttacgtca aatctatgaa caagtacctg gattagggaa tatgttaagt
     8641 gatgttcgtc tagaacctca tgaaaaacga gaaatcatgg acaagcttgt cagcggttat
     8701 gatgggatcg ttaaaaactt tttagaagtt gtttatgagt ataaccgaat ggatgacctt
     8761 ttgttcatga tcgaagaata tgaacgtcga tatgatgaac atcaagggtt actattggga
     8821 agtgtcacaa cagcagtccc actttcagac gaacaacgaa tacaattaga aaagaatgtt
     8881 gcaaaaacaa tggactatca atcagttgaa ttaaaacaaa tcgttgattc ttctattatt
     8941 ggtggcgcga ttgttgaagc caaccatcga gtaatcgacg gaagcattcg cacgcaatta
     9001 gaaaaaatgc gtaatcaatt aaacagatag tacaaagagg taggtgaatc gaatggccat
     9061 caaagcagaa gaaattagtg ccttgattaa agaacaaatt gaaaattatc aaaacgtgct
     9121 ttcagtcgaa gaaatcggta ccgtaactta tgtaggtgac gggatcgctc gtgcacatgg
     9181 tttagaaaac gcgatgagtg gtgagttgct tgaattttca aacggctcat acggaatggc
     9241 gcaaaactta gagtcaaatg atgtaggtat cattatcctt ggcgatttcg agtccattcg
     9301 tgaaggagat aaagtaaaac gaacaggtaa gatcatggaa gttccagttg gagaggcctt
     9361 gatcggtcgg gtagtcaatc cgctaggtca accaatcgac ggactaggtg aaatcgttac
     9421 tgacaaagct cgtccagtag aagcgatggc accaggtgtt atgcaacgta aatctgttaa
     9481 cgaaccaatg caaacagggc taaaagcgat cgacgccctt gtgccaatcg gacgcggaca
     9541 acgtgaatta gtcatcggtg accgtaaaac agggaaaact tctattgcga tcgatacgat
     9601 catcaaccaa aaaggtcaag atatgatctg tatctatgta gcaatcggac aaaaagattc
     9661 tacagttcgt acacaagttg aaacattgaa aaaatatggc gcaatggatt acacaatcgt
     9721 tgtgaatgcc ggtgcgtctc aaccagcacc attgctttat atcgcaccat atgctggtac
     9781 tgcaatgggt gaagaattca tgtacaacgg taaacatgta ttgatcattt ttgatgatct
     9841 ttcaaaacaa gctgttgctt atcgtgaact ttccttgctg cttcgccgtc caccaggtcg
     9901 tgaagcttat ccaggggatg ttttctactt acactcacgc ttattggaac gtgcagcaaa
     9961 attaagtgat gatttaggtg gcggttcaat gactgcctta ccatttgttg aaacacaagc
    10021 tggagatatc tctgcttata tcccaacaaa cgttatttcg atcactgatg gacaaatctt
    10081 cttagaaagc gacttgttct acgcaggtac tcgtccagcg gttgatgccg gactatctgt
    10141 atctcgtgta gggggttctg cgcaaatcaa agcaatgaaa aaagttgctg ggactttacg
    10201 tctagactta gcaagttacc gtgaattaga agcatttaca caattcggtt ctgacttgga
    10261 tgcagcaaca caagcaaaac taaatcgtgg acgccgtaca gtagaaatct tgaaacaaaa
    10321 attgcatgca ccgctagctg ttgaaaaaca agtagtgatt ttgtatgctt tgacacatgg
    10381 attcttagat agtatccctg tagacagtat tttagacttc gaacatgaat tattcgaata
    10441 tctggatacc aatcattcag atatctttga aacaatccgt acaacaaaag atcttccaga
    10501 agaagaagcg ttgaacagtg cgattcagga atataaagac atgttcttag ctacaaaagg
    10561 aaataattcc tctacagaag ataaattgaa atccattcaa aatgcatagt gaggtgagat
    10621 gaatgggtgc ttcattaaat gaaatcaaga cacgtatcgc ttcaacgaaa aaaacgagcc
    10681 aaatcacgcg ggcaatgcag atggtgtctg cttctaagtt gacaaaatct gaagcttctt
    10741 cacagaagtt tcaggtttat gcaacaaaag taagagaaat cgttacgcat ttgactgcta
    10801 ctcagttaaa tgatattgcc tcagaaaatc ctagagggga tatcaattac aacagcatgt
    10861 tgctcagccg tcctgttaag aaaacgggtt atatcgtcat cactgcagat ggcggtttag
    10921 tcggtggata taacagctcg atattgaaac aaacgatgtc tattttagaa gaagaccacc
    10981 aatcacccga tgattacgtg atgatcgcaa ttggcggaac tggtgcagac ttctttaaag
    11041 cacgcggtat caatctagca tatgagctgc gcaatctatc tgatcagcca agctttgatg
    11101 aagtccgcaa aatcgtaaat atggcaacaa ctatgtacca aaacgaagta ttcgatgaat
    11161 tatacgtatg ttataaccat catatcaatt cgctaactag tcagtttcgt gtagaaaaaa
    11221 tgctgccaat ctcagactta gatccagaag aagcaactac tttcgaacaa gaatatattt
    11281 ttgaaccttc aaaagaagaa atcttgtctc agttattgcc tcagtatgct gaaagtttga
    11341 tctacggtgc gatcgttgac gccaaaacag cagaacatgc tgctggtatg acagcaatga
    11401 aaacagcaac tgataatgct gctaatatca ttgatgagct gacggtttct tacaaccgtg
    11461 caagacaagg ggctattacc caagaaatta ccgaaattgt tgccggagct tcggcactag
    11521 aatagtattg agattggagg aaaaaagatg agttcaggca agattgttca agtaatcggt
    11581 cccgttgtcg acgtggaatt ttctttagac caatccttac cagatatcaa caacgcatta
    11641 gttgtttata aaaatgacga aaataaatca aaagttgttc ttgaagcagc gttagaatta
    11701 ggggacggag tgatccggac cattgcgatg gaatcaacag atggtttaca aagaggaatg
    11761 gaagtcattg atacaggcaa agcaatctct gttcctgtag gtaaagaaac attaggtcgc
    11821 gtattcaacg tactaggaga tacgatcgat ttagaaacac ctttcccaga agatgcggaa
    11881 agaagcgaaa ttcataaaaa agcaccagcc tttgacgaat taagtacaag tacagaaatt
    11941 ttggaaacag ggatcaaagt tatcgatttg cttgccccat atttaaaagg tgggaaagtc
    12001 ggactattcg gtggtgccgg tgttggtaaa accgtactga tccaagaact gatccataat
    12061 atcgcccaag aacatggtgg tatttctgta tttaccggtg taggtgaacg tactcgtgaa
    12121 ggtaatgact tgtattatga aatgaaagat tcaggagtta tcgaaaaaac agccatggtg
    12181 ttcggacaaa tgaacgaacc accaggtgca cgtatgcgtg ttgctttgac tggtttgacg
    12241 attgcggaat atttccgtga tgtagaaggt caagatgtac tgttgtttat cgacaacatt
    12301 ttccgtttca ctcaagctgg atctgaagta tcagccttgt taggacggat gccttctgcg
    12361 gttggttatc aaccaacatt ggcaacagaa atgggtcaat tgcaagaacg tatcacatct
    12421 acgaaaaaag gttcgatcac atcgatccaa gcaatctatg tgccagccga tgactacact
    12481 gacccggcgc cggcaacagc attcgcccat ttggatgcga caaccaactt ggaacgtaaa
    12541 ttaacagaac aagggattta tccagcggta gatccattgg cttcttcttc aagtgcttta
    12601 gcacctgaaa tcgtgggaga agaacattat aaagtagcaa cagaagtcca acacgtattg
    12661 caacgatatc gtgaattaca agatatcatt gctatcttag gtatggatga attatccgat
    12721 caagaaaaag tgttagtttc tcgtgcccgc agagtccaat tcttcttgtc acaaaacttt
    12781 aacgtggctg aacaatttac tggtcttcca ggttcatatg tccctgtaga agaaacagtg
    12841 aaaggattcc gcgaaatctt ggaaggcaaa tacgatgatc ttcctgaaga agctttccga
    12901 agtgttggcc gaatcgaaga cgtcgtagaa aaagcgaaaa cactaggcta ctagaaaggg
    12961 gtgccccatg gatcaatatt taacagtaaa tgtggtaact cctgccggtt tggtctatga
    13021 tcaccatgca gctatcgtcg ttgcacgtac gacagctggt gagcttggga ttttgcctaa
    13081 acatgcacca atcatcgttc cattgacgat tgatgaagtt cgtgtaaaac gaacagattc
    13141 agatacccac gtcgattgga tcgctgttaa tggcggaatc atggaagttc gtgataatgt
    13201 tgtttcaatc gttgctgata gtgcggaacg tgaacgtgat atcgatgtat ctcgtgcgga
    13261 acgtgcaaaa caacgcgcag aacgccaaat cgaagaagca aaagcaaaac aagatacgaa
    13321 cgaattgaaa cgggcaactg ttgcgttgca ccgagcaatc aatcgtatca aagtatctaa
    13381 gcactcataa aatgagatgc ggatgtttat ccgtgtttaa gaacagtaaa aagaggttat
    13441 gacagaagtg gtcagcttca agacataaga aggaatttac gaaaattgct tctcaaattt
    13501 ttgtgaaatc tcagcttatt tttcgaagaa gctacttctg gaacaccgta tatcggaggt
    13561 tgtgaaatca gcgttttgtc ctgagtatta gagaaacaaa tggaaaatag ttcctcatat
    13621 tttgccgttt tttgagctaa taccgagggt cagatgattg aacaccgttt atttggaata
    13681 agggactgcg acaagacttt t
//
LOCUS       DADVXB010000072        13681 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.073, whole genome shotgun sequence.
ACCESSION   DADVXB010000072 DADVXB010000000
VERSION     DADVXB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.073"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..620)
                     /locus_tag="KB902_001682"
     CDS             complement(<1..620)
                     /locus_tag="KB902_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6808510.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKD"
     gene            complement(868..1704)
                     /locus_tag="KB902_001683"
     CDS             complement(868..1704)
                     /locus_tag="KB902_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBB6808511.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(1715..2644)
                     /locus_tag="KB902_001684"
     CDS             complement(1715..2644)
                     /locus_tag="KB902_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBB6808512.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            2836..3189
                     /locus_tag="KB902_001685"
     CDS             2836..3189
                     /locus_tag="KB902_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6808513.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(3263..3919)
                     /locus_tag="KB902_001686"
     CDS             complement(3263..3919)
                     /locus_tag="KB902_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6808514.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            4145..6079
                     /locus_tag="KB902_001687"
     CDS             4145..6079
                     /locus_tag="KB902_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6808515.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(6165..7388)
                     /locus_tag="KB902_001688"
     CDS             complement(6165..7388)
                     /locus_tag="KB902_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6808516.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7382..9280)
                     /locus_tag="KB902_001689"
     CDS             complement(7382..9280)
                     /locus_tag="KB902_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBB6808517.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(9274..10392)
                     /locus_tag="KB902_001690"
     CDS             complement(9274..10392)
                     /locus_tag="KB902_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6808518.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(10475..11308)
                     /locus_tag="KB902_001691"
     CDS             complement(10475..11308)
                     /locus_tag="KB902_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6808519.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(11301..12218)
                     /locus_tag="KB902_001692"
     CDS             complement(11301..12218)
                     /locus_tag="KB902_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6808520.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(12445..13569)
                     /locus_tag="KB902_001693"
     CDS             complement(12445..13569)
                     /locus_tag="KB902_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6808521.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         4274 a         2728 c         2242 g         4437 t
ORIGIN      
        1 aaatctttac ataaatactc atattcgagt gattttttat attttttaat tgtgccgttt
       61 acgagaatct cttcatcttt caatactagg cctattttat ttttataacc tggcatgctc
      121 attagataaa ggatttcatc gtaatggata tagtgatcgc tattaccata acggacagtt
      181 gtccaccttt ttttcgtagc atgttgaaca ggatagtttt ctttttcttt caataagtaa
      241 ctttggatgc tttttttatt tttttcataa gtgaattctt ttatcaaata accactaggc
      301 gtaatctttc gattaataac agttattgct ttattcggat gagacgttag ataaacaatt
      361 ttacactttt cattcttttc tctaagcatt tcgcctagtt cgataccgct ataataggcg
      421 ttcaaatcga tgtctaggaa aaaaatatct gaggaataga tttcattatt tttaatgaat
      481 tcaacaaatt gtataacgtt caatccctga acgatctcaa atttccaagg acttaataaa
      541 attctggatt cttccaaaat ttctactagc attttttcaa aaaccaaact atcatccaaa
      601 ataaatatac gcgttaccat aaaaagtacc tccactcgat attttactat caaaatcatt
      661 tcatacaact tttcaacata catgttagga ataaattgta attctcttca caatcttttc
      721 caacaccttt gaaaccgata tcaaatactt tcaggatgct gcttctaaaa taaatatcaa
      781 acaaatgaat acatcatgca aaaaaagcca gacaaccgac gtccttgcgt gtcagctgtc
      841 tgagctatgt ttatttattt tgttctttta aaaagaacga tacacatact gatttttcgg
      901 agcagagact ttctcagcgt ttgtaacaac tacagatggg atttcacgct tgaatggttg
      961 ataatagtct gattggatgg ttccttctat tttataccat tcatcatttt taaccgttac
     1021 tccttccggc atatgcgtca acaaaccaaa gactcctgaa tctgccacac aatggataat
     1081 gccgaatcgg aacaagaaga tatctgtatt gctatcgttc ggtgtttggt aaacaaatcc
     1141 ttcatagctg atttttttgc caatgaattc gctagggtaa ttataaatta gctccataac
     1201 ttctaaatag ttttcatctg tgatcttgat agtttgctta tccccatact tttctttcaa
     1261 ctcattcatt tggtctaagt agtctgattt gttgaaataa atactggtat ccggctttaa
     1321 gtattgtgtc tgcatctccg gatcccctac tgattcttta cttactggga aattaaatcc
     1381 tttggcttct acgatcgtag tgtcgagact aactgttgga aacaacgtcc ccacgattac
     1441 tggcaaagct agcagtacat aagcgattcc acgttgataa ggttttgaca acccatggtc
     1501 atgatcgtgc tcgtgtgcct tttcttctgc ttttccgttt ttgacccaca aatacagctg
     1561 aactaaagcc aaaagagcag ataaaatcat tgaaagaata gctaagtagc gataatggac
     1621 attgatatat tgatcgagtt tgccagaaac ttgcaagtac atcatcaatt cgaaataccc
     1681 agataaaatc aaaaaccgca gcatattttc cctcctaaat aaataatgtg aatccaataa
     1741 cgctaagggc aatcagtccg atcagcgata aaataaagcg tcctgtaaaa tatcgtttca
     1801 tcatcagtag atttttgata tcgaccattg ggccaaagac caaaaaggca gctacaggtg
     1861 ctgtgccgaa cagacttaac aaagaagatc ctataaacgc atctgcttct gagcaaagag
     1921 acatcgtaaa ggccaataac agcatgatga taatggctaa aatctttgtt gagccgagcg
     1981 ttagcataat tctagttggt aaataagtct gcatcgcagc tgcgattaat ccgccaatga
     2041 tcaaataacg acctgtatca aaaaattcgt cgattgaatg tgtcaacaca tgcccagttt
     2101 gatggatcag ctgatttttt ggttcattct tctcactttg ttcttcttca tggacatgat
     2161 gatggtgatt ttctgctact ttagacgtga ttttttcttt caatacagcg tctttttgaa
     2221 aataggcaag ccagacacca atcacaaggg caacaaaaaa gctgcctatc acccgccagc
     2281 ttgccatctg ccaagaattg ccaaatgcga taaaagtgga aaaaatcacg attggattga
     2341 tgatcggagc agtcagcata aaagcaaacg ctgtgtgaac tggtacgcct tttttaacaa
     2401 attgatgaac gatcggtacg atgccgcatt cacatgaagg aaagaaaaat cctaagatcg
     2461 aaccagtaaa aatagagaag atacgatttt caggaagcca tctcttcaca cgttctgggg
     2521 tcaaaaatac ttgtaaggcg cctgagataa gacagcctaa taatacgaaa ggtaatgctt
     2581 caataacgat cgataagaaa atcgtactca tctgcaaaac cgaatttgga ataaaagaaa
     2641 acatgagttt cctccttttt atttctagtt cattcgcttt gcaaatatac gcttttattc
     2701 aaaaaaaaca agttgctctg taaattttta cacaactctt attttttacc aaagcacttc
     2761 aattgacttt ttctgttatt cccattaaat taaggtctca tacatatcac ttctatcata
     2821 aaagggagaa taaaaatgaa acaaaccact aacttgactg aagttcaaga catactgcaa
     2881 cagtcatccg ttgccgtcat ttatctttcg atgcctaatt gcagtgtttg tcacgctgtt
     2941 cgtccacgac tagaggaact tctcacacat tatgatattc cggcacttca tttggatgca
     3001 tttgaaacac cagaagtagc tagtaaattt gaagtgctga ctgcgccagt tgtcctgatt
     3061 tttcatcaag gaaaagaagt ctttcggcaa gcacggttca tcgactttaa aaaaatccgt
     3121 tatctactag atgaactgac agcagaagat gattcccttt cttatgaaga aatcttccga
     3181 acaaaataat cgttgtccaa acagaaaaaa gcgattgaac aagtgaaagt tttgccttca
     3241 tttgttcaat cgctttttat ttttattctg ctgtattttc ggaatgcgca tttgcgtcag
     3301 aatgcaagaa atagatcaag gtttgcaatt cattcgtcaa atcaacattt tggatcaata
     3361 catctgacgg agcattcaat cgagcagcgg taaagttcaa gattcctttg attcctgctt
     3421 ccgttaactg attgactact tcttgtgctc tttcagcggg tatcgttaaa attgctactt
     3481 cgatttgttg gatcttgatt tgttctgaca tatcttccat tggataaacg gggataccgt
     3541 ctacgatgcg cccaacgatt tcctcattca catcaaaagc acaactgata cgtatgctat
     3601 tactttgatg gaatttgtat tttagtaaag cacttcccaa gttccctaca ccgatcagcg
     3661 caacatttgt caattgatcg tcgtttaatg tctttgcaaa aaagtgcata agatcttcta
     3721 catcataacc atacccacgt tttcctaatt cgccaaaata agaaaaatct cgacggatcg
     3781 ttgcactatc tacttgaacg gcttcactta attcagttga agacactttt ttctttccag
     3841 cattatttaa aatccttaaa tagcgataat acaaaggcag tcttttagct gtcgcctttg
     3901 gaataatatg atctttcacg aaatgacctc cacgtattgt ctaattacat ctttgatttc
     3961 tccatcatag cagtatttat aggaaaaaat caattccatt gctcagatat tgtgaaattt
     4021 tattctttat tcatttattt atcatttctg caaatctcgc agtataatgg aatttatggt
     4081 agactactaa ttgaaaaata gttttttatt tgaggagaat tcacaaagta gaaaagagga
     4141 ttccatgata ttattacaag ccaatcagat tgctcgccat tttggtgcag aagtcttatt
     4201 tgaaaacata catttagaaa tcagtacagg cgctcgtgtc gctttagttg gcagaaatgg
     4261 cgctggaaaa tcgactttat taaagatcat tgctggaatt gaagcacctg atgaaggaaa
     4321 gatcgctaaa aataaaacag cgactctcgg atacctcgct caggacacag gacttgattc
     4381 caatgaaaca gtttggaacg agatgctgaa agcttttgaa caagttagac aaatggaaga
     4441 gcggatgcgc gagctagaga ttttcattag cgaaggtacg ccagacacac ctgcttatag
     4501 ttcttattta aaagaatacg accggctgca acacgatttt tcagatcgaa acggctatgg
     4561 ttatgaaaat gaaattcgtt ccgtattgca tgggtttaaa ttcgattctt cattttatga
     4621 tcagaaaatc gatactttat caggcggaca gcgcacacgt ttagctttag ctcgcatgct
     4681 tttgcaacac cctgacattt tgattctaga cgaaccaacg aaccatttag atatcgagac
     4741 actttcctgg cttgagaatt atctgcaaag ctatactggt gcattattga ttgtttccca
     4801 tgaccgttat tttttagata aagtagtcaa tgaagtctat gaattaagca gaagaaaaat
     4861 gcgccattac aaaggtaact attcgaaata tctagatttg aaagcagaac agttagcaag
     4921 tgaatggaag gcttatgaaa agcagcaaac agaaatccat aaattagaag acttcgttgc
     4981 tcggaacctt gttcgcgcct ctaccacaaa acgagcgcaa agccgcagaa agacattaga
     5041 aaaaatggac cggctggatc gtcctcaagg ggatgaaaaa caagcaaact ttctattcag
     5101 tatagaaaag ccttctggaa atgtagtctt gcaaatcgaa gatgccgcta tcggatatga
     5161 taatgtcacc ttatctgaac caatcaatct agatatccgt cgtcaagaag cgattgctct
     5221 agtaggtccg aatggtatcg ggaaatcgac gttgctgaaa tcaatcattc accagatccc
     5281 ttttatccgt ggaaaagaaa cgctagggac aaatgtcacc atcggctatt acgatcaagg
     5341 tcaagctgat ctgcatacaa acaagacgat cctagcagaa ttgtgggatg agcatcctac
     5401 cactccagaa aaagagatcc gaagtgcttt aggtgctttc ttattttctg gcgaagatgt
     5461 agaaaaacca atccctctgc taagtggcgg tgaaaaagca cgggttgctt tagccaagtt
     5521 agcgatgaac aaagaaaatt ttttgatttt ggatgaacca acaaaccatt tagatattga
     5581 caacaaagaa gtattagaaa atgcattgat cgattatgac ggcacactgc tttttgtttc
     5641 ccatgaccga tatttcatca atcggatcgc gacaaaagtc gtcgaactct ctgaaaatgg
     5701 cagcaaagtc tatctaggag actatgatta ttatttagag aaaaagcagg aagaagaaga
     5761 aatcgccgaa ttgttggcac aagatgagcc agaatctgct cctgctccca cgaacaaatc
     5821 tgattattac caaagcaaag aacagcaaaa gcttatccgt agccttcaac gaaaaattac
     5881 tcaggttgaa gaagaaatgg cgcggatcga tgaatggatc gatcagttgg aacaagaaat
     5941 ggtcgcgcca gaaaacctgg aagatcacgt aaaactcaat gagctgaacc aagatttaga
     6001 agctgctaga caagatcaag aaacaaaatt gacggaatgg gaagaactaa gcttggaatt
     6061 agaagaatat gaaaattaac gaaaaaacca aaacagaaac cattcatgct gttttggttt
     6121 ttcttttttt attttatcaa acaaaaattc catatttacc tttttcacca ataagaagac
     6181 caattactag tcattctcac taaagcttct aaataatagt aatcacccca aatacaaggt
     6241 gtatttaccc cattattttt gggcttatta taaacagact gtgttaaaaa gccatcttct
     6301 tcttccgttg tagcatatct ttctttcaat tgtcgcataa ttttccaaac agcagactgg
     6361 tataagttct tttctgtttt gtctaataga cctgattcta ttaattctaa taatccacaa
     6421 accatgatca ccatactaga tgtatctttt tcttctctgc tagaatcatc aaagatcaaa
     6481 tcccaataac aaatggtatc ttctggcaac cgattcataa aataattggc taatattttg
     6541 cttaaatcaa aatatttttg ttctttcaaa taacgataac ttaatgcaaa accgtaaatc
     6601 ccccatgctt ggcctctagc ccaacaggaa ttatcactat aaccttgatg cgtacttcca
     6661 tatcttggtt ttccatcttt gacatccata taaaatgtat gataagttga accatcttct
     6721 cttactaaat aatctgctgc attttgaata tgagcctgag cagctttttt atatttttga
     6781 tttccagttt cttcactcgc ccaatacaat aatggaagat tcatgcaaca atccatgatc
     6841 attctacctt gttgtgaagg atcactagga tctccccaag cttgtataac tcctgccttc
     6901 tcccaaaaac gctgaagtaa tgtttctgca gcatcaattg aagcttcctt catttttcga
     6961 tttcccgtta ttttataatc tgctacggtt gataaagaat acaaaaaacc aagatcgtga
     7021 tgattagtga taatttgaca gtcaatcctg tggataaaat ctatatctgc tttttcagct
     7081 gtttgttgaa ataaaggatc acccgtcttc tcaaataaca accaattaat tcctgtccaa
     7141 aatccttctg tccaaccaat attgtctctt aatggataac gtccttttat aggacactcg
     7201 cttgggaatt gatactgact gttactgata cgtttgatta acctctccgt gtgtctgcga
     7261 caacgctcga tctcattatt ccattctttt tccattaatt ctttataaca ttcatttatc
     7321 catttttctg gatgtattat ctcttcaaac atcactttat caagcatttc cccaccagcc
     7381 tttagcataa ttttagtctt tttttattgt ttttattttg gatagttagc ccggttgtcc
     7441 catcaaaatc aattttggga cgattgttcc atacttctaa actataatcc cgatcttgat
     7501 gagcaaccac tcctgttccg agccaatggg ttccttttcc aaatgtaccc tctaatccag
     7561 gaataaaagt gttttcccat gtcatcaagt ttgtattggg caaacccata atagctgtgg
     7621 attttcgttt aatagtatcg tcacttaaac agataatacc tgaaaagcca gcttcactca
     7681 ccctatagtt ttccttgtct tcttctatga ttattccttc tttctcagga gaacattcaa
     7741 tagcaaaccc tgtctcatat agaacatatt ctgtatctaa ttctactttg tgtacgcgaa
     7801 tctgccagcc ttcaaaagga ataagccaag ttctgatttt tgcctgtaaa gtaggttccc
     7861 atgtagaggc aagtacctct ttcttacata caatgtctcg tacattattt cgaacgatga
     7921 actgtccata ggttttgatg ctctcattct taaaactggt cgtgatatat gtgtccgctc
     7981 gctgaatccc tagcattgaa tccattgcca tttctgcttt caattgattc gctcgcggta
     8041 tcgaaaaacc aaattgacta gaataagcaa attttaaata tttttcattg gtcaatgtat
     8101 ggaaatttgg ccctaattgt cccgcattca aaaaaaatgt atgtccatta tcatgttgta
     8161 tgagcaaatt ggcttctgaa agaagtttag ttccttcacg aataggcata ggcatttctt
     8221 tagccgtcca atactcatgg tcttcaggta gcgccaacaa taaaaaaatc ttattcagcc
     8281 ataatggaga taacgtacta ttatagggtt cagtcaatgt caattgaggg taggtataac
     8341 caatattcag gatacctttt tcatcaaata tttctttttg catccaccat cttatattcc
     8401 gattgactaa ccccttgatt tcacctaatt taaaaggcaa aagatcggcc cacaacatag
     8461 ctgaccaaaa gcttgaaact gcaaaacgat aaatcatgct tcgaccaaaa ggcacatttg
     8521 caccatcttc cgcaaaaaaa tgaatatagt ctctagaaaa atcaatagct cggttcttat
     8581 atatctggct aatgggcttt tctggttcta gtacgctata aatcaaacca taataatgaa
     8641 atgcaaaagg attataataa tcttggcgac ctcttgaact gtctcgatac cagccatttt
     8701 gaagataaca attttctata ttatcaaatg cttctttcag tgctgattct ttaactggat
     8761 aaccaaattt ttggataatt gttccgacaa ttatcttaaa aaattgccaa ttaccatctg
     8821 cacattcata ttcaaaaatt tgcgagaacc aatgaataat ctggcttttt tctcctgtat
     8881 ctaatttttt ccataataat tgttcatgat gatataacgc taataacatt gcgggcattt
     8941 ctaccatacg ctggtctctt tcatgtattt ctccccaata atcgggatgg gaaggatctg
     9001 ttccagcttt tattcctgat agaattaatt tcaaccatcg ttcatctaat tggtcaattg
     9061 cgggccccgc tccccataaa acccgagaga atccttccat tcctgcaatt ttatttccat
     9121 atcctacccc ttgatgtata taatcaattt gtgcgccact tgctcgataa aacggctgga
     9181 gtggttgatt tatcttttta aataagtcaa agtaatcctg tctggtcctt aatagtggta
     9241 ctggatgttt cattgtattt tctcctcttt ttactaccaa atagctaatt ccgactgttc
     9301 taatcgaagt aagccttcaa taaaaaaata atcagaatag atcagtggca cattataagt
     9361 cagttctcta tggtatgctt ctgctccgcc tccaatgatc ccatcttcat ccatattcca
     9421 atttgcatag tgcttttctg tcttttggag tatattgata gcagcttcat gatacatttt
     9481 tgatcgtaca gaggaaacat atcctgctaa ttccagaaga ccgcatgcag cgcatactcc
     9541 agcactggta tcaatattcg aatcttttac agcaaaatca atgagaggaa tataaccagt
     9601 tttttcgatt ttctgaataa aatttactgc tatcttttct gctatagcta gatagtacgg
     9661 attttttgtg taacgataac ttaacgcgaa tccatataaa gcccatgcat ttcctctgct
     9721 ccaacaagaa ttctcattgt atccttgccc gccaagtaac cgaatatatt tccctgattc
     9781 tgcatcaaat tctgcgatat gcccggttga tccatctttc ctcactagat acttagctgt
     9841 tgtatctgca tgctgccgag caattttaga gaacctcgga tcaccagttt ccctcgaagc
     9901 ccaatacagt aatggtaaat tcatcatact atcaataatc atccaaccag gtttatggtc
     9961 attccatgct actaaatagt tccctgaaat attatagcgt ccagcaagta ccgtagctgc
    10021 atgtaaccct agttgtcgac tatgtttgtt ttgagactgt tgataatgtg caatagccga
    10081 tggtaagaat aaaaaaccta catcatgatg aacgtctgaa aaatggtaca gggcagattc
    10141 taataattgt tcttgttgta ttgctgcctc tttgaacttt tctcgttttg tcttgtgaaa
    10201 gagctgccat aaaataccac tccaaaaacc attggtccac cagtcgattc ctctgtcctt
    10261 tattacgtct gtatattttc cgttgtaaga aatatatgga attttattcc ccattctgtc
    10321 taattccgca tctatctttt cagaagctac attcaaaatt tttcttgacc attccttcgt
    10381 ctgttcattc atggatatcc cgccattctt ttaattttta tgaatgtgga gttgctccta
    10441 gaacgaacta gatggttaac attcgttatt ttttttactt atttgcagct ccaatgtcat
    10501 tctccttaaa tttagactgc gcccacacat aaatcaagac cattgggatc actgaagttg
    10561 ctaaaattag cataattgcg ccataattaa ttggctcacc tgtactagaa accgtcatat
    10621 ttttgataat taagggaacc gtatatttat ctttatctga aagcatgact aatggaaata
    10681 gatattgatt ccaacttccc ataaagataa gtaaaccact agtaataatc gtaggtgata
    10741 aaatcggtac agcgattttc gtaaaaatca cccactcatt ggcaccatcg attctggcag
    10801 cctccatcag tgctgtagga aattgactgc tatattgtcg catcataaac actgaagttg
    10861 tactggcaat cgaagggatg atcacacctg cataagtatt cgataatcct aaacgactca
    10921 taatgtaaaa taaaggaatc aatgtggtaa aaaaaggcac catcctagat agcataactg
    10981 tattgaacaa cagtttattc cccataaaac gatactttgc taatgcataa cccgccattg
    11041 tagaactggc tgtagctaaa actgtactga ttacagcaat aacaatcgaa ttccaaataa
    11101 tcaagggata attatatctc gccatgatgg cttgccagtt ttttaatagc atatccccaa
    11161 acttgaaatt gattccgcca cttaaaattt cttgattact ttgcgttgaa gctacaatca
    11221 tatataaata tggcatcaaa aatattaagg caccaaacac aataatgacg tacgtaaaaa
    11281 ttctgctttg tatcttttgt ttagtcattt ttatcacctc cgaatttaaa ttgaatagcc
    11341 gataatataa cagatacaaa caccatcgtc caggcaatag cagaggcttt tccaaaatca
    11401 accatttcaa aacttgtttt atataaattg actcctacga ccaaagctga attttctggt
    11461 ccattggaag tcccaaagaa tatatttggg atattgaaat tacccaagcc attgatagtg
    11521 gctaaaactg tggccattaa aatgattggc tttagcatgg ggatcgttaa taaaaagaat
    11581 tgccgaaatt tcgatgctcc atctatttca gcactttcgt atatctcttt agaaatccct
    11641 tgaagaccag ctaaaaataa aatagtgtta tatcctacac taagccaaat catcgtgatg
    11701 atcattgata ttcgtatcca aaaaggattt gttaaccact gtacaccgtt aattcctagc
    11761 gcattcaaaa atccattgaa taacccagtc ggattgaaaa aagtcatgaa tacggaagct
    11821 acagccaccg ttgatgtaat ggttggaata taatagacag ttctaaaaaa tccttttcct
    11881 tttaactgtg ctgaattcaa taaaacagca aagtaaatag ctaatagcat cgttattgga
    11941 attgatcctg ccatgataat caaaacattc gtgtaagatt taataaacaa tggatctcgg
    12001 aagatagcta gataattgtc aaatccaaca aattcaaatg agtagccaat tttcataaaa
    12061 ctaaaagcaa acgagataat gatgggaatc aaaatcgtca caataaagaa aataacaaaa
    12121 ggtgtgacca atccataagc acttttttta tgagacgtat ctgttgcttt tttcttgctg
    12181 ttctttattg tcttgcttgg taacgaagat tgcatcatcg ttaagtcctc ctaatatttt
    12241 ttaatcacca gttaatttta cgccgtactt atgagcaaaa ttttctgctt cttttagata
    12301 tgaattttca aaatcacctg tttgccaata gttatatgca gcggtagtca aataagacgt
    12361 agcatctgaa taagtggctg gtaaaacagt atttgatgta ttttcattga ttttattcaa
    12421 tagttcatag tatttttgtc ctccttagta gtcaaacttt ttctcagctg cttctgtttg
    12481 ataggccaat gagttagatg tagccacgcc cagctccagt gcgttggcta agcattcttc
    12541 atctgtcagc ataaatgtaa gaaattgttg tgccacttgt ggatttttgg catctttagg
    12601 gacataaaaa cttgatcctc ctgatactgc accttttcct ggattttctt ttgaaaaagg
    12661 aatcagtgga gccatgcgcc atttgtcaga tgcatcagga aaattcaaag acatattcgt
    12721 agcataccag ccgccagcaa caaacattgc agattcttga aatgctttct cagcatcttg
    12781 tgcaccgtag aaatgtacaa tatctgagtc gatcatttct ttgattaact ttgcagcatg
    12841 tttcgcttct ttagtattca gacggatatt tccttcttca tcaagcaaag attgattctg
    12901 ctgggctagc atgttgataa acaattcttg gtccccagat tctggcaagg caattccaaa
    12961 actaccagtt ttttctttta atgcttttgc cacctggata tattcttccc aagaactgat
    13021 ttcttcaaaa tctacaccta tttcagcaaa tttttttggt tgataataac aaagtgctgg
    13081 ggtaaaatca ctagcccaag gaataatcgt ttcattactc gtttgttgac gcaaaatatt
    13141 caatttttga tcataaaact gatcgccata tttgtcataa aatccatatt catcagcact
    13201 ataaaaagca tcttgaaatt tttccagcac acctgctgct gaagtgtctg ccatggagat
    13261 aatatccggc atatcttcgt gtgttaccaa ttttggggtg atcatttgta ctgttgctgt
    13321 tcccgaagct acattcacaa tttttaagtc aatatttgct ccagttttgc ggttatagat
    13381 ttttgcagca ttttcaacat agtttgtcag tttgccgttt gcgacatata cttctaatgt
    13441 agtggctttt tttatcattg gatctgcgat gtttgctgtt acttcttcgt tagtttttcc
    13501 acatgcactt aagctgaata atagggtaat gtttagcaaa gctatcacca atttgtatct
    13561 ttttttcatg tctatccctt ctttcttttc aagttcttat ataaaacgct ttcacttatg
    13621 tatattaacg gaattagtaa cacaaatatt tatataaaaa aatattttac ttgtcgtttt
    13681 g
//
LOCUS       DADVXB010000073        13667 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.074, whole genome shotgun sequence.
ACCESSION   DADVXB010000073 DADVXB010000000
VERSION     DADVXB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.074"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            68..310
                     /gene="yaaA"
                     /locus_tag="KB902_001694"
     CDS             68..310
                     /gene="yaaA"
                     /locus_tag="KB902_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBB6808522.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            297..1421
                     /gene="recF"
                     /locus_tag="KB902_001695"
     CDS             297..1421
                     /gene="recF"
                     /locus_tag="KB902_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBB6808523.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1418..3364
                     /gene="gyrB"
                     /locus_tag="KB902_001696"
     CDS             1418..3364
                     /gene="gyrB"
                     /locus_tag="KB902_001696"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBB6808524.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3384..5855
                     /gene="gyrA"
                     /locus_tag="KB902_001697"
     CDS             3384..5855
                     /gene="gyrA"
                     /locus_tag="KB902_001697"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBB6808525.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6091..6390
                     /locus_tag="KB902_001698"
     CDS             6091..6390
                     /locus_tag="KB902_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBB6808526.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6440..6952
                     /gene="ssb"
                     /locus_tag="KB902_001699"
     CDS             6440..6952
                     /gene="ssb"
                     /locus_tag="KB902_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6808527.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6978..7214
                     /locus_tag="KB902_001700"
     CDS             6978..7214
                     /locus_tag="KB902_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBB6808528.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7357..9330
                     /locus_tag="KB902_001701"
     CDS             7357..9330
                     /locus_tag="KB902_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBB6808529.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9336..9788
                     /gene="rplI"
                     /locus_tag="KB902_001702"
     CDS             9336..9788
                     /gene="rplI"
                     /locus_tag="KB902_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBB6808530.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10062..11429
                     /gene="dnaB"
                     /locus_tag="KB902_001703"
     CDS             10062..11429
                     /gene="dnaB"
                     /locus_tag="KB902_001703"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBB6808531.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12209..13501
                     /locus_tag="KB902_001704"
     CDS             12209..13501
                     /locus_tag="KB902_001704"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBB6808532.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4549 a         2464 c         3017 g         3637 t
ORIGIN      
        1 tttgttttat tgcgaaaaaa aaggtataat agagtatact tttaataatg aaaatgaggg
       61 atgggcattg aaacaacaag tcattctaaa tacggaattc atgacgttgg gccaaatgtt
      121 gaaagaagtc acagttatcg gtagtggcgg acaagcaaaa tggtatttgg cagaaaacac
      181 tgtgttagtc gatggcgaac cagaaaatcg tcgtggacgc aaactttatc ccggcatgat
      241 ggttgaagtt ccagaagtag gaactttttt tatggtaaaa aaaggaaacg acgataatga
      301 ggctgaataa gctgtattta aaaaattatc gaaattacga agagctgaac atcgaatttt
      361 ccaagaacct cgtcatcttt ttaggagaaa atgcgcaagg aaaaacgaat cttttggaaa
      421 gtatctacgt attagctatg acgcgaagtc atcggacaag tagtgagcag gaattgattg
      481 gctggactga cgatcaggcg atgattcaag gagagatcac aaaaggttca tccactcttc
      541 cattagaaat cttattatct aaaaaaggcc gaaaaaccaa gatcaaccat atcgaacaaa
      601 aaaagttaag tacttacgtg ggacaaatga atgtcatttt atttgcacca gaagatcttt
      661 ctttagtaaa aggcagcccg cagatcaggc ggaagttttt agatatggaa ttaggccaga
      721 tcaatccaat ctatctttat gatcttgtcc aataccaagc aattttgaaa caaagaaacc
      781 agtatttaaa gcaattgaat gaaaaaaaac aaactgattt gctttatttg gatattttgt
      841 ccgaacaact agcagcgttt ggcagcaaag tattgaaagc aagagcacag ttcgtcaagc
      901 gattggagtt ttgggctaat tctttgcatc agcaaatcac ccatcaaaaa gagcagctgg
      961 aaatcgagta tctcaccgca gtcgattctt tagaaacaca tacgcaagag caaatccaag
     1021 aacaatttct cgcacttttg aaccaaaata aaaagaaaga cctttttcgg ggaacaacga
     1081 cagttggtcc tcatcgtgac gatctttctt tttttattaa tcagaaaaat gtgcagactt
     1141 atggatcgca aggacagcaa agaacaactg cactaagtgt caaattagca gaaatcgatt
     1201 tgattaaaga agagacgggg gaatatccaa tccttttgtt agatgatgtg atgagcgagc
     1261 tggatgatag tcgtcaactc catctgctag aaacaatcga aggaaaagtt caaacgttct
     1321 taacaacaac gacacttgac catgtaaaaa ataaaatgac tgttgaacct gagatttttt
     1381 atgttcaaca agggaaacta aaaggagaag aaactgaatg acagaagaaa gaagtttagt
     1441 agaacgcgct aaagagtatg atgccagtca gattcaagta cttgaaggac ttgaagccgt
     1501 tcgtaaacga cctggcatgt atatcggttc gactagttct gagggtctgc atcaccttgt
     1561 ttgggaaatt gtcgataatt cgatcgatga agtattagca ggttttgcaa cgaaaatcca
     1621 tgtgattatt gaaaaagaca acagtatcac cgttattgac gacggtcggg ggatacctgt
     1681 agatatccag gcaaaaactg gacgtcctgc agttgaaacg gtctttactg ttttacatgc
     1741 tggaggaaaa ttcggcggtg gtgggtacaa agtttctggt ggacttcacg gagtaggatc
     1801 ttctgttgtt aacgcgcttt ctacacagct tgatgtcaaa gtatacaaag aaggaaatgt
     1861 gtactatcaa gaatatcgtc gtggagctgt agtggacgac ttaaagatta tcgaacaaac
     1921 ggatcgccat ggaacaacgg ttcactttac gccagaccct gaaattttta cagagacaac
     1981 tgagtttgat ttttcaaaat tggctacccg gatccgtgaa cttgctttct tgaaccgcgg
     2041 gatgcgtata tcgattgaag acaaacgaga agaagaacca gtcatcaatg aataccatta
     2101 tgacggcggg attaaaagtt atgtcgaata cttgaatgca aacaaaaccg tgatttttcc
     2161 agaacctgta tatttggaag gtgaacagca agatatcgca gttgaagtct ctatgcaata
     2221 tacagacggc taccattcca atatcatgag ttttgccaac aatatccata cgtatgaagg
     2281 cggaacacat gaatcaggat tcaagactgc tttaactcgt gtgataaatg attatgcccg
     2341 aaaacaaaag ctgatgaaag aaaatgacga caacttgacc ggtgaagacg tgcgagaagg
     2401 attgacagct gttatttcta tcaagcatcc tgaccctcaa ttcgaaggac aaacaaaaac
     2461 aaaattgggc aattccgaag tacggacagt cactgatcgg ttatttagcg aacatttcat
     2521 gaaattcttg ctggaaaacc caagtgtggg ccgtcaaatt gttgaaaaag gattactagc
     2581 ttccagagct cgtctagcag cgaaacgtgc gcgtgaagta acgagacgta aaggtgcttt
     2641 agagattagt aatctgccag gaaaattagc ggactgctct agcaacgatc ctgaaaaatg
     2701 cgaattgttc atcgtcgaag gagattcggc cggcggatca gctaagcaag gtcgtaatcg
     2761 agagtttcaa gccatcttgc ctattcgtgg gaaaatcttg aatgttgaaa aagcaagcat
     2821 ggacaagatc ttggcaaatg aagagatccg gtctttattt actgctatgg gtacagggtt
     2881 tggagaagat tttgatgtat cgaaagctcg ctaccacaaa ttagttatca tgactgatgc
     2941 cgatgtcgac ggcgcgcata tccgtacatt gctgctgact cttttttatc gttacatgcg
     3001 tcctattgtt gaagctggat acgtctatat tgctcagcca cctttatacg gggtaaaaca
     3061 agggaagaat attacgtatg tacaaccagg aaaaaatgca gaagaagagt tgaaacaagt
     3121 cgttgcttca cttcctgcct caccaaaacc aagcgttcag cgttataaag gacttggaga
     3181 aatggatgat catcaactat gggaaacaac tatggaccca agcaatcgga tgatggcccg
     3241 cgtcagtgtg gacgatgcta ttgcagcaga tcagatattt gaaatgttga tgggggatcg
     3301 agtagaaccc cgtcgtgcat tcatcgagga aaatgcacac tatgtgaaga acttagatat
     3361 ttaatcatga aggaggaaaa agaatgagtg aagaaatcag agaaaacatc catgatgtca
     3421 atctaaccag cgaaatgaaa gactccttca tcgattatgc gatgagtgtt attgtcgcac
     3481 gtgcacttcc tgatgtcaga gatggtctga aacccgttca tcgccgtatt ttatacggca
     3541 tgaacgaatt aggtgtaaca ccggataaag cccataaaaa atctgccaga atcgtcggag
     3601 atgtcatggg taaataccat cctcatggag acattgcgat ctatgagtca atggtacgga
     3661 tggcacagcc attcagctac cgttatatgc tagtggatgg tcatggaaac tttggttctg
     3721 ttgacggtga cggtgccgcc gctatgcgtt ataccgaagc acggatgagc aaaatcgcta
     3781 cagaaatgct gcgtgatatc aataagaaca ctgttgattt ccaaagcaac tatgatgata
     3841 cagaaaaaga accagttgta ctacctgctc gcttcccgaa tcttttagtg aacggaacaa
     3901 cggggatcgc cgtaggtatg gccacgaata tcccacctca taacttgtct gaggtagtag
     3961 cggctatcga tttgctgatg gataatcctg atgtgacgac caatgaattg atggaagtat
     4021 tacctggacc agattttcca acaggtggtt tggttatggg aaaatcagga atccgaagag
     4081 cgtatgaaac aggtaagggt tctattaccg tacgtgcaaa agttgagatt actgagatgc
     4141 caaatggtaa agaacggatc atcgtgacag aattgcctta tatggtcaat aaagcaaaat
     4201 tgatcgaacg gatttctgaa ctgcacagag acaagcgtat cgaagggatc acagatttgc
     4261 gggacgaatc ttcccgtgaa ggtatgcgga tcgtcattga catccgtcgt gacgccagcg
     4321 catctgttat cttgaataac ttatataaat tgacatcctt gcaaaattca tttggattca
     4381 atatgttggc gatcgaaaaa ggtgtgccga aagttttgag cttgaaacaa attcttgaaa
     4441 actatatcga acatcagcgc gaagtcatca caagacggac agtctttgaa aaagaaaaag
     4501 cagaagcaag ggcacacatt ttagaaggtt tgcgtattgc tttggatcat atcgatgaaa
     4561 tcattgcgat tatccgcggg tctaaatcag atgacgaagc aaaagcgacg atgatcgaac
     4621 ggttcgattt atccgatcgc cagtctcaag ctattttaga tatgcgttta cgccgattga
     4681 ccggtttgga acgggaaaaa atcgaaaatg aataccaaga actcttaaaa ctgattgaag
     4741 atttaactga cattctggca agaccagaac gtgttacaga aatcatcaag aatgaattag
     4801 cagacttgaa tcaacgattt ggtgataaac gacgcacaga attactagtc ggtgaggtct
     4861 taagtctgga agatgaagat ttaatcgaag aagaagaaat cgttattaca ttgacaaaca
     4921 atggttacat caaacgtttg gcaaataatg aattcagagc tcaacgaagg ggtggacgtg
     4981 gtgtccaagg aatgggtatc cacaatgacg acttcgtcaa aaatctggtt tcttgttcta
     5041 cccatgatac attgttattc tttacgaata acggaaaagt gtatcgggca aaaggatacg
     5101 aaattccaga atacgggcgc acagccaaag gaataccaat tatcaattta ctaggtatcg
     5161 attcgagtga aagcatccag gcaatcattg cggtgacggg agaagcagaa gaaggccact
     5221 atctcttctt tacgacgcgt caaggtacag taaaacgtac ttctgtcact gcttttgcta
     5281 acatccgaag taatggtctg atcgcaattg gtttgaaaga agacgatgag ctcgtcaatg
     5341 tgctactgac agatggtcaa tctaatatca ttattggaac acataacggc tactctgtca
     5401 ctttcaaaga agaagcagtc cgcgatatgg gacgtacagc ttccggggtt agaggaatac
     5461 gcctgcgtga ggaagattat gtcgttgggg cagccttaat gaaggaagat caagaagtat
     5521 tagtgatcac agaaaaaggt tacggaaaac ggacaaaagt atcggaatat ccagtgaaag
     5581 gccgcggagg taaagggatc aaaacggcga acatcactga aaaaaatggt ccactagctg
     5641 gattgaccac tgtttctgga gatgaagaca tcatgctgat tacagataaa ggtgtcatta
     5701 tccgtttcaa cgtatcgact gtttctcaaa ctggacgttc aacattaggc gtacgtttga
     5761 tgaagatgga agctgatacg aaagttgtca cgatggcagc agtcgaacca gaagctgcag
     5821 aacaaacagt tgaagaacaa ggatcagaag aatagccatc aagactaatt gtgtaagcta
     5881 gcaagaatga ccgattaaaa aatctggtta ttcctgctgg cttttttgat tagttgaatt
     5941 tctcttaaaa tattcgaaac tgttcattct gtattgcttt tgaccaaaat agagtgtata
     6001 atcagagctt gtgagtagtc taattaatta gataactctc cttgctctta ggaacctaag
     6061 agccgaaagt ccacagggag gtgaatatca atggaaaaca cgaaatatga aatcatgtac
     6121 attattcgtc caaacattga tgaagaagca aaaactgctt taatcgaacg tttcgatgca
     6181 atcttgaaag ataacggagc agaagttatc gaatcaaaag attgggaaaa acgccgtttc
     6241 gcttatgaaa tgaacggtta ccgtgaaggt atctatcaca tcgttaaagt atcttctcca
     6301 tcatcagcaa atgctgtcaa tgaatttgac cgtcttgcta aaatcaacga cgatatcatt
     6361 cgtcacatga ttgttaaaga agaagcttaa ttgttgtttc atgtgaaaca atagaaaacg
     6421 atgagaggag atgactattt tgattaataa tgttgtatta gttggacgtc tgacgaaaga
     6481 tccagatttg cgttacacag caagtggtac ggcagtcgca acatttactt tggctgtgaa
     6541 tcgtaatttt acaaaccaaa gcggcaatcg cgaggctgat tttatcaact gtgtgatttg
     6601 gcgcaaatca gcagaaactt tagcaaacta tgctcgtaaa ggaacacttt taggtgttac
     6661 tggacgtatc caaactcgtt cttatgataa tcagcaagga caacgtgtat acgtgacaga
     6721 agtagtagct gacaacttcc aattgctgga aagtcgttct gcatctgaaa atcgccaaca
     6781 aagcggcgga ttccaaagtt ctggtcaatc agctggcgga tttggcggaa acaataactc
     6841 taatcaaaca tctcaatcat ccaacggtat gcctgatttc gaccgtgata cttctgaccc
     6901 attcggctca agttcaacga tcgacatttc agacgatgat ttaccattct aaacgaattt
     6961 gataggaggg aaatagaatg gcacaacaaa gaagaggcgg acgtaaacgt cgtaaagtag
     7021 actacattgc tgctaaccat attgaatata tcgattataa agatatcgaa ttactaaaaa
     7081 gatttatttc agaacgcggt aaaatcttgc cacgtcgtgt aactggtaca ggcgctaaaa
     7141 accaacgtaa aattactgtt gcaatcaaac gcgctcgtat catgggcttg ctacctttcg
     7201 ttagcgaaga ctaataaatc ctaggaattg aatgactgat ccttttgatc agctattcaa
     7261 ttcctttttt tctgtaaaaa taacctctat tcgtttagtc gctcgaatga cgaaagttat
     7321 ggtaaaatca aattagtcat atatgggagg aaaattatgg aaaataaaaa caatcattta
     7381 tccccgaaac ctctcttcct tatcctgttt atattaatcg aagtattggt agtcttaatt
     7441 ttaccatttc gttttgttag cgcttcggtc attctattga tgaatttatg gggtgttcgc
     7501 tattggttga aaatgaaacg ttggcttatt ttaaataaac gtgaaaaaat ccagcaggct
     7561 tcgactgtag ctgaaaccaa tctagcttat gtctcagaag tcatgcctgt aggagtgatt
     7621 gcttatcagc catcaagcca aaaaatcgaa tggctcaatc cattagcatt gaaaatcaaa
     7681 gatcaaagtg gattaacaga ggaagaattg ctagatactt tttttactgc aaaagaaaaa
     7741 aagaaaaacc aagtctatct agcagataaa acatttcagt ttgatatgga tacagtaaag
     7801 ggtgttgttt attttaatga tattacccaa aaccagttgt taaaactcca tcagacgaac
     7861 agtcagccgg tgattggtat tttatctatt gataactatg cagatgccat tgataaattg
     7921 gatgacaaag agatttctta tttgaactct ttcgtcacta cactagtttc tgactggatg
     7981 aatgaatacc atgtcttttt caaaagaatc aacgcagaac ggtttttctt cgtagcacag
     8041 atgatcgatc tgaaaaagat gatggataaa aaatttgatt tgctggatcg ctttcgagca
     8101 gaagctgaaa aacagagctc gcctatcacc cttagtatgg ggattgctta tggctcaaga
     8161 accctcgatg aaatcggtgg agaagctcag aataatttag atgttgcttt agtccgtgga
     8221 ggcgaccaag ttgtcgtgaa agaggtaaaa gaaggagcaa aacctgttta ttatgggggg
     8281 aaatctgcta agaatgtcaa acgcacgcgt gttcgttctc gagcgatgag taccgctttg
     8341 cgtcggattt ttgatgaaac aggcgatgtg tttatcatgg ggcacaagtt tccggatatg
     8401 gatgctttag gctctgcttt tggtgtcagt tgtctggcac gcttcaacca gaaaaaagct
     8461 tacatcgtta tcaacgagaa cgagatcatt ccagatgtag aacggtgtct tgaagaaatc
     8521 cataagcatc ctgaattaga aatgcaacta atctctccag aacgtgccat agagctgaaa
     8581 aaagaagagg acctcctcgt gatggtggat taccataaac cttctctatc gatctctcag
     8641 ggcctatatg agcaatttga taagattgtg atcattgatc accatcgtcg tggggaagag
     8701 tttccaagta aacctctgct gacttatatc gaatcttcag cttcttcagc ttcagagcta
     8761 gtttctgagc tgatccaata ccaaagcagc aaaacaaatc gcttagatcg ttttgaggcc
     8821 acattattgc ttgcagggat ggttgtagat acaaatagtt tcaatgtccg tacaactgca
     8881 cgaacttttg acgttgccag ctatttaagg tcttgtggag cagacgcatc cttagtacaa
     8941 tatttattga gctcggattt agcgacatac ttggagatca gcaatttgat tgctggaagc
     9001 gactatgtga cttctgatat tgttgtggcg gcagggacag acgaaaaaga gtataatagt
     9061 gttatagcag caaaaacagc agatacattg ctttcgatga tcaatatcaa tgcagctttc
     9121 gtcattacaa agcggacaga cggcttgatt gggatcagtg ccagaagtac cggcacgatc
     9181 aacgtccaaa tcatcatgga atccttaggt ggcggaggac acttcacaaa cgcagctact
     9241 caactggaaa atacgacagt tgaggaaaca aaacagaagc tatttgctgc aatcaaagaa
     9301 aatatgaatc aaatatatga taaggagtaa tccaaatgaa agtaattttt ttacaagatg
     9361 taaaaggaaa aggtaaaaaa ggggacatca aagaagttcc agcaggttat gcacaaaatt
     9421 atctaatcaa aaataacttg gcaaaagaag caacgaaaag cagtatcagt cagttagcag
     9481 gacaaaagaa agcacaagaa aaacacgaag ctgaaatctt ggaagaagct aaaaagttaa
     9541 aagaattctt ggaaaaagaa gatactgtag tcgaattgaa ggcgaaagca ggggaagaca
     9601 gccgtttgtt tggttcgatc ccttcaaaac aaattgctga agggttaaac aaacaataca
     9661 aaatcaaatt agataaacga aaaatcgaat tagaaaatcc gatccgttca ctaggctaca
     9721 caaacgtacc tgttaagctt catcatgagg tgacggctac gatcaaagtt catgtcgtac
     9781 aagaataaca aatcttgata gcgatgttca gctggtaagt ataaccagaa ggaaaaaaga
     9841 caaaccgaaa tttatctgag aaaacagctg cagcaatgaa agcaaaagct gcaaatcgat
     9901 ttcagattga tttcggtttc ttttttggga acagcaaaat agcataaaga aaacgagtat
     9961 aataaaagag aactattttt ttattacact ttcggtacga atgatgactt ttctctcatt
    10021 ttcttgtaaa atgaagcaat tgaagacaag gagcgatacg tatgaatgaa gtgtggcagg
    10081 atcgaatccc accgcaaaat attgaagctg aacaagcggt tttaggctct gtttttcttg
    10141 acgcagaaac gatcattgat gccatggagt acatagagcc aaaagacttt tatcgtcgtg
    10201 gccatcaaat tatttttgag acaatgatcg agttaaatga tcgtaatgaa gcgattgacg
    10261 tggttactgt caaagaccgg ctggaacaag ccaatttgtt agaagatgcc ggtggtttaa
    10321 gttatctctc agacttggca ttagcagttc cgacagcagc aaatatcgtc tactatgcga
    10381 aaatcgttga agaaaaatca ttgctgcgta cattgatcca gacagcaaca ggaatcgtta
    10441 cgaaaggatt cgagcaagga gaagaagttc aaacaatttt agatgatgcc gaacgcagta
    10501 tcttggaggt ttcggaaaaa agaaatcgaa gcggcttttt atctattgct gaagtactga
    10561 actccacgat tgaaaatatc gatcgactag ctcaaaacaa tgaagaaatc acaggtctac
    10621 caactggcta tcaaggtctg gataaaatga cagcaggttt ccagcccgaa gaactaatca
    10681 ttctggctgc tcgtcctgcg gtaggtaaaa cagcgttcgc attgaatatt gctcaaaatg
    10741 taggaaccaa aacagatcgt tctgttgcga tattcagtct ggaaatgggg gcagaatctc
    10801 ttgtaaatcg gatgctttgt gcagaaggtt cgattgaggc cagccattta cgtacaggtc
    10861 agctttcgga agaagaatgg tcgaatctga tcgttgcgat ggggagtctt tctcgagcaa
    10921 atatttttat cgatgataca ccagggatca aaatctctga aatccgtgcg aaatgtcgga
    10981 aactagcgca agaaaaaggc aatctaggtt tgatattgat cgattatttg cagttgattg
    11041 aaggtaacgg taaagagaac cgtcaacaag aagtatcaga tatctctcgc caactgaaaa
    11101 aactggcgaa agagctgaaa gtacctgtca ttgctctttc acagttatct cgtggagtag
    11161 aacagcgaca agacaaacga ccagtgctaa gtgatattcg tgaatccgga tcaattgaac
    11221 aagatgcgga catcgtagcc ttcttgtatc gagatgatta ttatgaaaga gaaggcggag
    11281 atgacgatga tggaaacgag ccaaaaaatg acaacgtcat cgaagtcatc atcgagaaga
    11341 accgaagcgg tgcacgagga acagttgaac tactgtttat caaagaatac aataaatttt
    11401 cgtcgctttc gccaagagaa gaattttaaa gaagaggttg tgagccttga gcaatgccga
    11461 gagcactcgt aagaagatgc gaggagtaac cgcaggaacg actagagtac ttaatttaaa
    11521 cagatctcca aagggattgt gacaaaagtc ttgtcacagt ccctttttcc gaataaacgg
    11581 tgttcaatca gctgaccctt ggtattagct cagcaaacgt caaaatatga ggaactattt
    11641 tgacgtttgt ttctctaata ctcaggtcaa aacgctgatc ttacgacctc ttttccttaa
    11701 acggtgttct cctgccaact cctcggtcac aagtcacaat atcatcaaac atgagaagca
    11761 gttttttgaa attgctcctt gtgactcaga gttaaacggc aggctcacaa cctctttctt
    11821 aaacggtgtt caaaagcttg catctgcggt aatacgccca atcaaacgaa aaatatgaga
    11881 agctattttt gtttggctgt tcttattact tgatgcagga cagctttttc acaacctctg
    11941 attcacggtg ttccaaaagt agcttcttcg aaaagtaagt cggaatttca caaaaatttg
    12001 agaagcaatt ttcgtacatt ccttcttatt tcttgaagct gaccacttct gttacaacct
    12061 cttttttaat aaccattcta aaaagataaa gttcgttttt taagcgtttt tataaaataa
    12121 aaataaaaat cattcgattt tatttgaaat atgtatctat tattgataca atggttcagg
    12181 attaaataat atagaacgag gtgttcacat gtcatctgta gtagtagtag gtacgcaatg
    12241 gggcgatgaa gggaaaggaa aaatcacaga ctttctcagt gaaaatgctg aagtgattgc
    12301 acggtaccaa ggtggcgaca atgcagggca cacaattaag tttaacggtg tgacttataa
    12361 actgcatttg attccttctg ggatttttta taaagataag atcagtgtga tcggaaacgg
    12421 cgttgtagtc aatcctaaat cattggttaa agaattagct tatttacatg aaaaaggtgt
    12481 agaaacaagt aatttgcgta tttctgaccg cgcgcacgta atcttgcctt atcatatcaa
    12541 attggaccaa ttacaagaag atgctaaggg cgaaaataag attggtacaa cgattaaagg
    12601 aatcggacct gcctatatgg ataaagcagc tcgtgtaggt atccgtattg cagacttatt
    12661 agataaagaa atttttgaag aacgtcttcg tttgaatcta gatgacaaaa accgtcaatt
    12721 tgtaaaaatg tttgattcag aaccacttga ttttgacgat atttttgaag aatattatga
    12781 atacggacaa caaatcaaac aatacgtcac agatacttcc gttatcttga atgatgcctt
    12841 ggatgcaggc aaacgcgtgt tgtttgaagg cgcacaaggt gtaatgctgg atatcgacca
    12901 gggaacttat ccttttgtta cttcttctaa cccagtagcc ggtggggtaa caatcggaag
    12961 cggtgtaggg ccttcaaaaa tcaataaagt tgtcggcgtc tgcaaagcct atacgtcacg
    13021 tgtcggtgat ggaccatttc caactgaatt atttgatgaa acaggagaac aaatccgcga
    13081 agtaggacga gaatacggta cgacaactgg tcgtccgcgt cgtgtcggct ggtttgattc
    13141 tgtagttatg cgccattcta aacgagtttc aggtattacc aacctatctt taaactcgat
    13201 cgatgtatta agtggattgg aaacagtaaa aatttgtacg gcttatgaat tagatgggga
    13261 actaatctac cattatccag caagcttgaa agagttgaac cgctgcaaac caatctatga
    13321 agaattgcca ggctggtcag aagacattac aggatgcaaa acacttgcag aactgccaga
    13381 aaacgcacgt aactatgtac gtcgtatctc agagcttgtt ggtgtacgta tctcaacatt
    13441 ttctgtcgga cctgatagaa cacaaacaaa catcttagaa agcgtctggg cgcaaatcta
    13501 aggataaaaa cgacgactga atcaggacgt tcttaccaga gcgagtcgaa gtgtttatct
    13561 atacgataat aataacttga agaggtagtg aaagagacgt ttagccttat tgccgatagg
    13621 ctgtctcttg aacactgttt attcagaata agggactgtg acaaaaa
//
LOCUS       DADVXB010000074        13601 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.075, whole genome shotgun sequence.
ACCESSION   DADVXB010000074 DADVXB010000000
VERSION     DADVXB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.075"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..570
                     /locus_tag="KB902_001705"
     CDS             <1..570
                     /locus_tag="KB902_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808533.1"
                     /translation="VYYNYFYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEV
                     LPDIYDDHYDSDGTCKVSIEKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTI
                     IVRGNSIDGVRKVNRSLILEIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFF
                     GRSRRFKLYVLQKDYASNGKYSKKYRIFI"
     gene            608..997
                     /locus_tag="KB902_001706"
     CDS             608..997
                     /locus_tag="KB902_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6808534.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            981..3431
                     /locus_tag="KB902_001707"
     CDS             981..3431
                     /locus_tag="KB902_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6808535.1"
                     /translation="MMYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHD
                     NFRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSM
                     IGDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEE
                     IRRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKS
                     ETLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQ
                     QQQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSV
                     DELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMG
                     LHKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKP
                     ALASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWK
                     ETLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEK
                     FPVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGS
                     ITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNRE
                     IFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGL
                     KFAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVF
                     EELFHAFDTRPPVQERME"
     gene            3436..5544
                     /locus_tag="KB902_001708"
     CDS             3436..5544
                     /locus_tag="KB902_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6808536.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            5541..6545
                     /locus_tag="KB902_001709"
     CDS             5541..6545
                     /locus_tag="KB902_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6808537.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            6564..7475
                     /locus_tag="KB902_001710"
     CDS             6564..7475
                     /locus_tag="KB902_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6808538.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            7662..7919
                     /locus_tag="KB902_001711"
                     /pseudo
     CDS             7662..7919
                     /locus_tag="KB902_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8137..8352)
                     /locus_tag="KB902_001712"
     CDS             complement(8137..8352)
                     /locus_tag="KB902_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808539.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8611..8778)
                     /locus_tag="KB902_001713"
     CDS             complement(8611..8778)
                     /locus_tag="KB902_001713"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6808540.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(9123..10562)
                     /locus_tag="KB902_001714"
                     /pseudo
     CDS             complement(9123..10562)
                     /locus_tag="KB902_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(11110..11781)
                     /locus_tag="KB902_001715"
     CDS             complement(11110..11781)
                     /locus_tag="KB902_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBB6808541.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(12130..13581)
                     /locus_tag="KB902_001716"
     CDS             complement(12130..13581)
                     /locus_tag="KB902_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBB6808542.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
BASE COUNT         4327 a         2473 c         2591 g         4210 t
ORIGIN      
        1 gtgtactaca actattttta ttttgtattt tgggtagcag caactttact tggttatgat
       61 aaaattcaga ttgcaggaat tcctatacac atgcaatata agttggtttt gagtggaatt
      121 ttttctgagg tgttgccaga tatatacgat gatcattacg acagtgatgg aacatgtaaa
      181 gtaagcattg aaaaagaaaa tttcgatgac atcgatggat atgactctgt gaacttactg
      241 attattgata cttacgatat aaaaatgagt gaattatcta tggaaaatca aacatatcct
      301 acgataattg ttagagggaa ttcaatagat ggagttcgta aagttaatag atctttaatc
      361 ttggaaataa aaaaaacaat ggatgaaatt caaaaaagtg actttaaaaa agtatttgtt
      421 gcttcaacat ctaatccaaa aaatagtatc aatattatta attcatcgtt tagatttttc
      481 ggtcgatcac gtaggtttaa actttatgtt cttcaaaagg attatgcaag caatggaaag
      541 tatagtaaga aatatagaat ttttatttaa gaaggaattt ttccttcttt ttattttgga
      601 ggaaactatg aaaaaaataa aaagctacac cagtatttgg gcagttgaaa aagtcattta
      661 tgcgattaat gactttcagc tgccttttcc tgtgaccttt aaccagatgg cttggtttgt
      721 tttatccttg atgtttgtca ttgtatttgc ccatgtgcct ccgctatcca tgatagaggg
      781 ggctttttta aaatacttgg gcattccgat agcggtcact tggttcatgt cgcaaaagac
      841 ctttgacggt aagaaaccat tgggattttt acgatccttt atcagctatc acttacggtt
      901 taaggtcact tttgcaggaa agaaagttaa agaacagaag aaacgatggg acgaaccaat
      961 caccttggta aggagtgtga attatgtacc cgattaagta tattgaaaat aatcttgtct
     1021 ttaaccaaga aggcgagtgt tttgcttact atgaattagt gccttacaat tactcctttt
     1081 tgtcacctga acagaagtat caagtacatg ataactttcg ccaattaatt gcgcaaaatc
     1141 gtgaaggtaa gatccatgcc ttacaaattg ccacagaaag tagtattcgt gccacacaag
     1201 aacgttcgaa aaaggaaatt accggtagac tcaaagaagt agcaaagcaa cgaattgatt
     1261 tacagacaga tgcattagta tccatgattg gcgatagtca gattgattat cgcttcttta
     1321 ttggctttaa actgatttcg acagatgaag aggtcaatct aaagaatctc aggaaatctt
     1381 tcttttctgg acttcaagaa tttgtctatg gagtgaatca tcatttgatg ggtgattttg
     1441 tttccttatc caatgaagaa attcgtcgct ataccaagct tgaaaaacta atggaaagta
     1501 aattggctcg aagatttaaa gtcaaacgag taacgccgag tgacttgacg tatttaattg
     1561 aacatatcta tggtgaaaaa ggcacaccgt ttgaagaata tgaattccag ctaccaaaga
     1621 aaaagctgaa atcagaaacg ctggtgaaac gttacgactt attacgtccc actcgttgtt
     1681 tgattgaaga aaagcctcgg tacttacgga tggaacatga aaatcatgag tcttatgtag
     1741 cgtacttaac aattaatacc attgtagggg aaatggagtt tccttcctcg gaacttttct
     1801 attaccagca acaacaattt acgtttccga ttgatacttc aatgaatgtg gaaattgtga
     1861 cgaataaaaa ggccctagct accgttcgta ataagaaaaa ggaattaaaa gatttagaca
     1921 accatgccta tcaatctgat aatgaaacga actccaatgt attagatgct ttggattccg
     1981 tggatgaatt ggaaaccacc ttggatcagt cgaaagaatc catgtataaa ctaagctatg
     2041 tggttcgagt gagtgctaaa tcagtggatg aattaaaacg ccgctgtgat gaagtgctcg
     2101 atttttatga cgataccaat gtaaaactag tccggccctt tggcgatatg atgggtctac
     2161 acaaagaatt cttaccctca agtaagcgat acatgaatga ctatattcaa tatgttacgt
     2221 ctgacttttt ggcgggactt ggttttgggg ctactcaaat gctaggagaa ttagaaggca
     2281 tttactttgg ctataacgta gatacggggc gcaatgttta cctgaaaccg gcattggcat
     2341 cacaaggggt caaaggctca gtaaccaatg ctttggcatc tgctttcctt ggttcgttag
     2401 gtggggggaa atcttttagc aacaatctct tagtctatta tgccgtcctt tttggtgggc
     2461 aagctgtgat tgtcgatcca aaaggagaaa gaggcggttg gaaagaaacg ttgccagaaa
     2521 ttgcggatga aattaatatt cttaacttga ccagtaagcc agaaaatcaa ggcttacttg
     2581 atccctatgt gattatgaag aaaaagaaag actcagaaag tttggcgatt gatatcctga
     2641 cctttttaac agggatttcc agtcgggatg gggagaagtt ccctgtgtta cgcaaagcca
     2701 ttcgaacggt tacccaaagt gatcagcgag gattattaca agtaatcgtt gaattgcgta
     2761 aagaggactc accagtcgcg gaaaatatcg cggatcacat cgagtccttt accgattatg
     2821 attttgccca tttgcttttc tcagatggtt cgattaccca gtcgattagt ttagataagc
     2881 agttaaatat cattcaagta gcggatttgg ttttaccaga tgcagaaacc acttttgaag
     2941 aatataccac catggaattg ctgagtgttt ccatgctaat tgttatttcc acttttgcct
     3001 tggactttat ccatagcaac cgagaaattt tcaagattgt ggacctggat gaggcttgga
     3061 gttttcttca agtagctcaa ggaaaaacgt tatcgaataa attagtgcgt gctggtcggg
     3121 ccatgaatgc cggtgtttac ttcgtcacgc aaaacagtga tgacttgttg gatgaacgtt
     3181 tgaagaataa tattgggcta aagtttgcat ttcgcagtac cgatattcat gaaatcaaga
     3241 aaaccttgga attctttgga ttagataaag aagatgaaag taatcaaaaa tgcatgcgag
     3301 atttggaaaa tgggcaatgc ttgatgcagg atttgtatgg tcgagtaggt gtggtccaag
     3361 ttcatccagt ctttgaagaa cttttccatg cttttgatac ccgtccgcca gttcaagaga
     3421 gaatggagtg aggagatgaa aaagaaactt tttcgtatct ttggaattgt tttaatcagt
     3481 ttggtcactc tgataatact tttgagctta gttggaacgg tagctgaggc aacaggtctg
     3541 gttgatgata cagttggagc cggaaatctt tattcccaat attcacttgg taactatcag
     3601 ttggatttct ttgtggatag ttcgtgggat tggctgcctt ggaattgggg tgatggccta
     3661 gggaagagcg taatgtatgg actttatgcc attactaatt ttatttggac agttagtctc
     3721 tacttatcaa atgccacggg ctacgtggtt caagaagcct ataagctgga tttcatttca
     3781 gatacggctg aaagtattgg gaagaatatc caaaccttag ccggcattac cgaaaatgga
     3841 ctccagacct cgggctttta ctttgggttt ctattattga tgattttagc tctaggagtt
     3901 tatgtggcgt atacaggatt attaaaacga gaaactacca aagcagtccg ggctgtcatt
     3961 aattttgtga tgatttttct actttcgggt tcgttcattg cgtatgcgcc cacctatatc
     4021 acaaaaatca atgattttag ctcagatgtc agcgaagcgg ctcttagcct tggaaccgag
     4081 attgtcgtgc cgaattcaga aagccaagga aaggacagtg tggatttaat ccgagatagc
     4141 ttgttttcca ttcaagtcca acaaccgtgg ttactcttgc aatttgatga ttccaatata
     4201 gaagaagttg gcgaagatcg tgttaacaaa atcctgtctg taagtccaga tgaaaataaa
     4261 ggcaaggatc gggaagaagc ggtcaaagcg gagattgaag ataatgacaa tgcgaatctc
     4321 agtattacca agaccatgaa ccgcttaggg accgtggtct ttttggtgtt gttcaatatt
     4381 ggcatatcct tctttgtctt tctcctaaca gggattatgt tgttctcgca aattctcttt
     4441 attatctttg cgatgttttt gccgattagt ttcttattgt ccatgttgcc gacttatgag
     4501 agtttgggca agaaggcgat tattcgcttg ttcaatacga ttatgatgcg agcaggagtt
     4561 actttggtga ttacgactgc atttagcatc tccacgatgt ttttcaatat ttcggcaacc
     4621 tatccatttt tcatggttgc ttttctgcaa attgtgacct ttgccggtat ctatttcaaa
     4681 ttgggcgaca ttatgaatat gttcaatctc cagagtaatg atagccaatc aatgggaaga
     4741 cgggtcatgc gaaaaccgca aatgttaatg aatcgaacat tgcggcaact caatcgaaat
     4801 gtgggacgga ctttggcttt tggtggtggt gcagcagttg gaaataagtt ggcaaaggaa
     4861 caatcaaaat ccaaatttaa gccatccggt tcttctctac gaaagaattc acgattaccg
     4921 aacgatcacg agataccatc tgacttgaat aaggaaaagc caattccaaa taataagaaa
     4981 caatcccgaa tgaatttggc cgggagaaaa gtcggcaagg ttctggatac ccaagctttg
     5041 gtgaaagata agaccaaaca agtaaaggat ggagtacgga atacgccaac caacttgaaa
     5101 tacaacttcc ataaaggaat tgaaaaaacg aaaaaagcac cggaagagtt taagcgagga
     5161 ctggtccaag aaaaagcaaa tcgaggagag ttgcgagaaa aacaacaaca acgtagagac
     5221 gaaaaaatag ctgaaaagcg caaagtattg aacgaaatag ggaatcctca tgggaaaaga
     5281 agggaaaatg ttccgataaa agcaaaggtc caatctcaaa aggatagagc accaaagcgg
     5341 attgtgagag caaattcgaa tcccgaaatc aaacgaaaat tcgctagcca agaaatcatt
     5401 tcaaaaggaa taaaccaatc ctcaagtaag aaaaattctt ttcaacaagt gaaacggcgg
     5461 tctactctgt ccaaacgaac caatcgaaaa gtacaaaaaa gtttgaaccc tcatcccaaa
     5521 ccaaggtcag gtgagaaaaa atgaacgtaa agaaattaag tgccatttcg ttaactttcc
     5581 taacaatctc ttttatgggt atcttgatgt gtgtgggctt attgtttggt gaagacagtg
     5641 aaggaagtag tagttcaggt gctcctcctg gggggagtag tgtctcagaa gaggttttga
     5701 aacaccgtgc aatggtggaa aaatatgcca aagaatcgga tataacagag tatgttccga
     5761 ttcttttagc gattattcaa gtggaatctg gtggcacaat ggaagatgtg atgcaaagtt
     5821 ctgagtcagc cggtttacca ccgaattcat taagtaccga ggcatccatc aaacaaggat
     5881 gtctctattt tgcgtctttg gttaagcgtt ccaaagaatt aggttgtgat caagatagta
     5941 tcattcaggc ctataacttt ggcggtggtt atttggacta tgtggcaaaa aacgggaaga
     6001 agcatagttt tgctttagct gaatcttttt caaaggaaaa atcttgcggt caaaaaatcg
     6061 attaccctaa tcccatcgcg aataaggaaa atggtggatg gcgctataac tatggcaata
     6121 tgttttattg cttattggtg aagcaatacc taactacaac acagtttgac gataaaacag
     6181 tccaagggat ttttgacgag gcgtttaagt atgaaggaac ggcttatgta tttggtgggt
     6241 caagacccga aacaggattt gattgtagtg gcttgactca atggtgttat gccaaagttg
     6301 gtctgaaact tcctcgggtg gctcaagatc agtatgatgc catgacccat attgacctaa
     6361 aagatgccaa accaggggat ttggttttct ttcattcgac ttatgatgcc ggtacttatg
     6421 tgacccatgt cggtatttat gcaggggaga atcgcatgtt tcatgcagga gatccagtag
     6481 gctggacgaa tctaacagaa agctattggc agcagcatct tatcggtgct ggacggtaca
     6541 aataagagaa aagaggaaaa agaatgaaga taaaaattga acggaatcaa aaggaaaaga
     6601 gcctaaaaaa gaaaaaagaa cgagtcgtat ccgtgggtaa gcatcgaaaa atggtgcttg
     6661 ccctttggct tttattatct tgtagtctta cttttggcgt ttataaaaat ttcaccgcca
     6721 ttgatcaaca tacaactcat gaaaaagtgg ttattaaaga gaaagtagtg aatacttctg
     6781 gtattgaaaa ctttacgaag gatttttcga aagaatattt ttcgtggaaa aataacaaag
     6841 aagcaattga aaagagaatg aacaacctcg aacagtacct tacagaagaa ggtttcgctt
     6901 taagtcaaga tatggttcga gcagatattc ccactaattc cgaagttcag tcagtaaaag
     6961 tcttagatgt tgaaaagagc tcggaggaat ttgtcgtttc atttttagtg gagcaaaaga
     7021 ttacagaggg aaaaaaggca caatcgattt cttctgcata ccgagtgacg atctttgaag
     7081 atgaaaacag gaattatata gtaacgagtt tgccaactat gattgcaaaa cctgataggg
     7141 caaaatacaa gacaaaacaa gtagaaaatg attcgaaaat tgatgccaaa actacagaag
     7201 aaatcgctga gtttttggaa acgttcttta aattatatcc atcagcttct gaaaaagaat
     7261 tggagtatta tgttgaaaat gatgcgatgc gaccaatcaa tattgactta aagttttcga
     7321 agttagagga tccagtttac ctacaaaacg gaaaaaaaat tctagtgagt acaaagataa
     7381 aataccttga taatgtatca aaaaccacta gctactttca gtacaaatta atattacaaa
     7441 aaaatggaaa ctggaaaatc attgatgtta aataataatg actcaatcta aatttatgag
     7501 aagttataag tagtttaact tatttcaggc agaagtcgcc catcctctat aggtgggtga
     7561 tgaatgccgt tcggtaactc gaaaaccgac aattaagaca tagtgccttt ttattttaat
     7621 ccatgtcata atcagtctat ataagaaatg gttgatatac catggaatta gatacaaata
     7681 atcattcatt atttcttctt tgttaccacc ttattttagt agtgaaacat tgtaaacatc
     7741 tcattgatga tgtaatgtta gcttatgcaa aaaactatct ttgaaagaat atcagaatca
     7801 catcacatta ccttagttga gtgaaatcgt gataaagact actttcatat tatgctcaaa
     7861 gcacaaccta aaaccgaatt aacaaaattc agcaatgcct aagctcatgt ctgataaaat
     7921 gagactttct aagggtcaaa aatttccttt gaatacgatc attagcttag ataaaagtaa
     7981 aaaccttaga actacgggga tagcttggtt aataagagat atggctgtta ataaagacat
     8041 aagcttgcaa gtatgctcta ttcccaagaa tctcccactt caagcactaa ggatcgttaa
     8101 attcagctaa gtggcaagta gttcactaga cgataattat ctccatattt caatctcagc
     8161 ttttccattt ttcatagcaa attccgttat ttttatagca tctaaaagat tcagcttttc
     8221 cactgatctt tcaccacttt tcagcttttt tattgtgctt aaattgatac cagtaccttt
     8281 tgatattgaa ttggaagtaa aatcattaag ggtttttttt attaaattca tatccgcaat
     8341 tccagcgttc ataagaatga agattctcct ctcatagact actttgaaaa tggtactaca
     8401 gtggctgttt atatatttca gtaggttact gtagtggtca ttttattata attagaaaag
     8461 gaacctaaat caaaaatgct aaagaaaatt ttcatagtat taaacctatc atgactaaag
     8521 ccacggaatt cttgataaaa gagtatactt gcaagcctat gtctttacta acagcgatat
     8581 ctcttattaa ccaatctatc cccgttgttc ctaaggttct tgatgttttc taaggcaatg
     8641 cttgtataca tagcccttga tcaaaatatt gatactaacg ttgacgtttc gatcatgatg
     8701 tgtacggcaa ataggacaag tccattctcg aattgtgaat gacttcttac catctgtgtg
     8761 tccacattct gaaccaattt gactagacgg aaatcattta tctatcttga tgattttttt
     8821 gacagaagta tcgaaaatct ttacataatc tgggtgttgc attcttatgc agatgagagc
     8881 gttagctccg tattcataac cagttgcctc taaaacgtag tccatcggtg gatacctagc
     8941 ttgcggttgc cagtggcttt cgcagtcttc ttgtaatcaa atcgagcatc taattgagta
     9001 ctagtatttt gaagataata cttgagtttt tcggttttca gaagttcact tcatcttcca
     9061 tcatccatgg aaatcccact cacccatacg caggcctcca aaaattcttc aacaatggtt
     9121 tttcagacat ttttctgaat acctccttgt tttttgatac gccagatagt caggaaaaag
     9181 gcaacaaaac acaaaacaaa gctgcctaaa aaggtaatct tcattccata taaaaagaca
     9241 tccggccgat ctgcgatata gttagttact cgttggccca tcttagcaga catcgcttga
     9301 tataagaccg tcgtagaaag cgaaatcccg atgaccatcc ccaaatttcg ggcaaaggaa
     9361 ttcatggagc ctgccagtcc caaattttcg atagtgacag aactcataac catcgtatta
     9421 tttggggact ggaacaaggc attgccggca cccatgatgg cagtagcgac aatgtacagc
     9481 cacaaaggag agtccactga caaaaacata tacatgactt gggttaccga caataaaccc
     9541 aagcctacta atacaaaaat ctccgggcca acccggtcgg tcaggtatcc gcttaaaggc
     9601 gccccgacga ccatcatcaa gggaaagacc atcatcaaca gtccggcata gctaggactc
     9661 aacccgcgag cattttgcag ataaaaagga atcactacat taacaaagaa gttggaagaa
     9721 aaaatcaaca aggctgtaat caagctcatg gtaaaaatct tgttcttaaa aataccgaaa
     9781 gaaatcaatg gagaggctgc tttcttttca acttttaaaa agctgacaaa ggcaatcact
     9841 gaaattacga acagtacaag ggggactgga tggaaaaagc cactttcttg ccccaaaaag
     9901 attgttccaa aaaggctgat aatcgtagcc gcaatggcag caaagccccc tccatcgatt
     9961 gtatggccgc tcatggtgat atcttttggt aagaattttt cagcaatcaa catcgttacg
    10021 attcccaccg gtacattgat ccaaaaaatg tacgcccaag aaaattggga caaaatcaag
    10081 ccgccaagac ctggtccagc aatcgagcct aatgaaacaa gcgcaccgat tgctcccaat
    10141 gcccgaccac gttcatgtat gggaaagact tccgtgatga ttccggcatt tgtagccata
    10201 gtcatactag caccaatggc ttgtaccacc cgtgcgaaca attaaatacc tagcgaatga
    10261 ttgaacccac acaacagcga gcccaagaca aagatcagcg taccaatccg aaatactttg
    10321 attttcccac agctatcgcc aattttacca aacagcaaca aacaagaaca gacaatcatc
    10381 agataaacgg acactaccca ttccgcttga ttcattggta tgcccatatc atctgagatg
    10441 gtaggtagtg caatattgac aatactgcca tccaatgtgg acatgaaggt aaacatagat
    10501 atagcaatca aaatccacca gcgatttttt tggacttttg catcttcttg ataactatgc
    10561 ataataggat ttcctttcta atgatcgtgt agctaagaac aatataacct atgtctactg
    10621 cccaacaact tctcgcgact ctagccatag gaagcttgag taatttcgat ttgttattct
    10681 catgtaacca tgtaagtttg agatgcttta tttgaactta ctctatagta actagtgata
    10741 attcgcttta ctttcttcta gcaatttcta aaagtcgact tcattgttct tcagattaat
    10801 agtgtgagct atctcgtgag acgtaagaaa atttccattc tactttttcc caattttttc
    10861 atatttatgg tgttgcacct atttgttttc caatttgctt ttcaaataca ttgctatgat
    10921 attcaattcc ataggattat actaaatgtc aatagtatga ataatatatt atagatgttt
    10981 atatatcact gttaattatt atccacaata attaatgatt acctcgatat ttgtcaatca
    11041 aaggttgaaa caatttattt tcagcatctt ttctaacttg agctgcactc ttaatagaat
    11101 catacgatcc taaatagtac ctcttttttt taaagttata tacgcaatcc atttctcttt
    11161 agaacgataa actcccttaa caccacttgt attatttttc ggtaattttg acgttagaca
    11221 ctctattact gtcccttcaa cacatgtcct tgtttcttgc ctttttaaac atccacaact
    11281 ttgagtatgt ccaaaaaata agttactata acttatctca cacatactgc cacactcaca
    11341 ttgacaaacc cattttgttt tccatgaaca gttattgtcc aaaggatact ttgcagtaag
    11401 taatccgaat tttttatttt caatgtgatg cttttttgat ttcaaacatc cacagctttt
    11461 tacatcacct tttagaagtc gctttgccga tactaacttt tttctcccac acagacattg
    11521 acattcccaa acaacagttc cttcacttcg cagtttagtt ggcttgattg caactaactt
    11581 accaaaagtt ttatttgtca aatttttata tttatgccta tttttataat ttccacatcc
    11641 acaacttttg gttctacctg atagtaagtt tgatcgatat acaatcgttt cattcccaca
    11701 gtcacatagg taacgatatt ttttatatcc attatgagta atctcctcaa caacagtaag
    11761 gtgaccatat ctttccttca ctgcacctac cctcccaaga aagaagtacc atataatttc
    11821 aattaacttt taataaatca gaaaaaaata ttttcaattt ttcttagtct gattttatga
    11881 ctaatttata atacaagact gaacgatacg tacacgaaat cctcaagata gataaattgt
    11941 tttcatctag taaaacctgc tcaaaatatg agcataaaga cggcaataat acactcgata
    12001 ttcgataatg gacttgtttt atttgtcaaa ctcatcgtaa tcgagatatc aattccagtc
    12061 tcaatatcct gatcaaaggt ctaagaatcc aaccattttc ttgttacttt gtcagattga
    12121 ttaccttttt tagtctccga ataataaggt tttcggatca actaacatgc tctgagaaag
    12181 actactatct ttgcaaattt ccaaatgaag gtgtgggcca gtactattcc cagtacttcc
    12241 tacatagcca attatttgtc cttgcaaaac attatctcca gtttttacta ggtattgttg
    12301 ctggtgagca tataacgcgg ttgatccatc ttcgtgttgt atcaccacgt aatttcccca
    12361 agagtagtga aactctgctt taacaacctt accagcttta actgcatgaa tcggctcacc
    12421 ctgtgtagct gccatatcaa gtcctcggtg aaattcattt ccacgatttc caaacaaact
    12481 ggttattgaa taattatgaa taggcacttg gtatccagtc ttactcattt gtggaccttt
    12541 aacttcttta tcatagttgg ttaaatcata ggttttaatt aattcattta gcttcaaata
    12601 gtattgtgta tctgttgcat accgtcctgt aaggaattta gttgcttctc gatatgtttt
    12661 actattagct tttaatgctc ctgcataaaa atctttattt ccactaattc ccttagttaa
    12721 taatttggca taatcttcaa aactttcctc atagttttca tacactctaa attttgattg
    12781 ggtcgtataa agcgttccat tacccaaatc ttcgtttgtt accataatga caaagtttcc
    12841 attataagtt ccttttatcc caaataaatt gtaattcggt gcctgagcta actggctttg
    12901 accactggca gattctaaga tcgcttgtgc aatcataaca gaagcatata aatcatattt
    12961 ctgaccaatt tttctcgcag actcaccaat tttcataata aaattttcta cagattcatt
    13021 tttgtcaaaa tgaatttctt cattaccaga tagtattggt tgtgattgga aagattctgt
    13081 tgattctatt tgctgtggtg tcgaaaaatt ttttgtttgt ccttccgttt ttggcgcttc
    13141 cttttttgaa gactctatat ggtttggtct tgtcactttc gaagaagtta tttcacttgt
    13201 actacttgaa gttgttgaag attcggcact tgaaatcgta ctactttcac ttgacgaagt
    13261 tgttgaagac tcggcatttg aagtcgtact actttcactt gacgaagttg ttgaagactc
    13321 ggcatttgaa gtcgtactac tttcacttga tgaagttgtt gaagactcag catttgaagt
    13381 cgtactactt tcacttgata aagttgtcaa aagttcacta ctctctgctg ttacatcgga
    13441 attactcatt tcagtcgtct cggttctttc ttttgcaatt ttgtatgttg aattttcgct
    13501 tgccaacaca tggaaaggtg ttgctataaa gagttgggac attaatataa ctgctgatgc
    13561 aagttttaaa gattttttca tttgatttac ctctcttttt t
//
LOCUS       DADVXB010000075        13556 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.076, whole genome shotgun sequence.
ACCESSION   DADVXB010000075 DADVXB010000000
VERSION     DADVXB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.076"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            30..3308
                     /locus_tag="KB902_001717"
     CDS             30..3308
                     /locus_tag="KB902_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBB6808543.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENKKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3849..5756)
                     /locus_tag="KB902_001718"
     CDS             complement(3849..5756)
                     /locus_tag="KB902_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBB6808544.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5886..6761
                     /locus_tag="KB902_001719"
     CDS             5886..6761
                     /locus_tag="KB902_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBB6808545.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6841..7815
                     /locus_tag="KB902_001720"
     CDS             6841..7815
                     /locus_tag="KB902_001720"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6808546.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            7995..9140
                     /locus_tag="KB902_001721"
     CDS             7995..9140
                     /locus_tag="KB902_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6808547.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9277..9621
                     /locus_tag="KB902_001722"
     CDS             9277..9621
                     /locus_tag="KB902_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBB6808548.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9892..11178
                     /gene="efmA"
                     /locus_tag="KB902_001723"
     CDS             9892..11178
                     /gene="efmA"
                     /locus_tag="KB902_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBB6808549.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11316..11915)
                     /locus_tag="KB902_001724"
     CDS             complement(11316..11915)
                     /locus_tag="KB902_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBB6808550.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12319..13440
                     /gene="mnmA"
                     /locus_tag="KB902_001725"
     CDS             12319..13440
                     /gene="mnmA"
                     /locus_tag="KB902_001725"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBB6808551.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
BASE COUNT         4314 a         2454 c         2890 g         3898 t
ORIGIN      
        1 ctttctaatt tgttacggga ggaatacact tgttaaaaaa acgtataaaa tacagtgcgc
       61 taatgatgaa tctccttatg ctcagtaccc cggttttaat ttctgtcgtt gaagttgctg
      121 ctaacgaaca acagtctgtg aacgaagaaa atgcacacgt gaacattgaa gggatgtcaa
      181 caatggagga aataccaaga actagtgaag atatggatac ggaagaagga aatgatccta
      241 tgatgaaaga atcagaaaat aaaaagacaa aaaagcaatc tgaagaagca aatgaagagt
      301 ggaaaggggt tgttttcgga gaaagcacaa gtgctagtag gtatgccatt gaaccattag
      361 aagacggcgt gcggctctct tccacgaata acggcggaaa attccagtca agcggatcag
      421 atggaatgac ctattattat caagcaatcc ccaaagacat caactttagg atgcgggcga
      481 cgatcgaaat agaatcttgg acctatacga atgcccaaga aggatttgct ttaatggtaa
      541 gagacgcagt accaaaaaat catttgtttg ggcaggcatt ttattcaaat tcatttgcca
      601 tactaggcag tcggatcgaa tatgtctggg actcggatag acaagaagtg gtcaacacga
      661 gcggcagcaa atatacgatg cgacttggat tggggacacg ggcaatcaca ggaatatcat
      721 ctgaagatcc gcaagctgcg ccagctcctg ggagtgtctc agtggaaaca acacctttag
      781 agacttcagc agggttcttg gaaaaagaaa caggttctta taatatattc ggaaacggtc
      841 atgggaatct gtttccggcc acgaactcga ttactaaact ggacgtagag atgaaaaaaa
      901 cgaatactgg tttagaggca tattattacg atcctgaaac aggagaagaa atggcttctg
      961 acatcatgta tgactgggaa aaattatacg cttcagatga atcggttatt tatgcaggat
     1021 ttgctgcagc aaggaatatg acgatcaagg tagaaggaat cgaagttgct tactcagatc
     1081 ctgcgacaga tcctcctggg caagaaagac ctactcgctt gattgatccg atttacactg
     1141 tgacctctag taatcattca ggaaaccaag atcatactat gtcctttaga gcaaatgctg
     1201 acggattatt gacaattaaa aataaagcaa caggagaggt gcttaagaac gcaaaaaact
     1261 tggctatcac tgcgaatcgg gaatttgatt atcagacaaa actgatggaa ggaacgaacg
     1321 aatttacttt cagttttacg ccagataaaa actatccgcc agaagaatac gtagagatga
     1381 ctagttatga aacaaaagag attcttcata cagtggacta ccgtaaacct aaatattcga
     1441 cagtttatgt aacaccagaa gggtcagatg caggaaacgg aagcagacaa aatccattat
     1501 ctctgacaca agcattgaga tacgcatatg ctgggcagac aatcgtcatg gcgcctggaa
     1561 cttattcctt cgaaagagga ttgacgattc caaaaggcgt taacgggaca agagaaaacc
     1621 cgattcagtt gattgcagag aaaaatccag aaaacaagcg tcctgtactt gattttaaag
     1681 gaactggaaa tgggatgaca ctgttcagtc actactgggg tttacgaggg tttgacatta
     1741 caaatagtgc agctatgcaa aaaggattac agatttctgg aaatcataat ttgatcgaag
     1801 agattcatgc ttatcggaat ggaaatacag gaatccaaat cagcggtagc tcaaatgatc
     1861 ctttcgaagc atggcccgcg cataacttag tcaagaactg tacatctttt gaaaatgccg
     1921 atccaggatt tgaagatgcc gatggatttg cggccaaact gacaatagga gaaggaaatg
     1981 tatttgacgg ttgtatcgcg tatcataatg cagatgacgg ttgggacctt tttgctaaaa
     2041 atgaaacagg ttcgatcgga aaagtaatca tcaaaaactc agttgcttat cgaaacggct
     2101 gggtaccagg aattgaggga gaaggtaacg gtaatggatt caaaatgggc ggttcttctt
     2161 taacgggccc tcatgaattg atcaatagtt tgtctttcga aaatcttgcg aaaggaatcg
     2221 attccaatag cggaacagat attatcgtca atagcagtac aagttttaat aacggttcat
     2281 ataatgtggc tctttatacc tcttcagcag gaaacacaga ctaccatgct tctggtatct
     2341 tatctttccg aacagagaat cttgagatga gagagcagat ccgcccattg aatcaaaacg
     2401 aagatcaaat ctaccactcg ttgaactact attggaatga acgagagaaa caatcagaaa
     2461 atactcttgg acataccata tcaaaagatt ggatcgagtc tctaaataca tgttcgaaag
     2521 aaggtcagca gcctgttacg cgctatgaaa atggaagtat ccatgttcat ggactgatgc
     2581 agattaaacc ggggaatcgt caaacagaaa aggaaagagt ggatggtctt ccattatctg
     2641 taggtgctat ttttgacgga gaaacctcac cgtcttcgga atatccagag tatgcaatcg
     2701 tacaagaacc aaatcagaca aaaccaaatg aacaaaataa tccgattatt atacaagaag
     2761 caaatggtgt ggcggagaat gcagaaggaa atatcattga actgaagcct tttacagttt
     2821 ttgtgtcaac tttcacacca aatcaaggaa cgcctgtctt tgaagatatg cgttatttcc
     2881 cagaaaagat ccaaatcgtt gaaacacagt caagtgctca attttctaat cataccgcta
     2941 ttttttcagc accttcaaaa ggagaatata cgctagaagt cacttatcgt tcggaaatat
     3001 ttgatgggga aaaatggtct gctcatacag aatctgttac ccagcaaaaa gcgatcactg
     3061 tgcgagaaac tgccgatgtg cccccgggaa atgacaaacc agaaagagaa aatccaggaa
     3121 atgaatcacc aaatggaaaa ccaaatggaa aaccttctca tccggatagg acagcaaaag
     3181 aaagtgaaaa aaatggcact caaggactcc caaaaacggg agaatttaat aacccgttgc
     3241 tagcattagc tggaggaatt ttgttaatcg gtgtagttgt ttatgtcatg aaacagcgaa
     3301 aaaaataagt ggaatttctc cttttatgat gtaaaacaat tgactgagga aagtaaaaat
     3361 agaaggaaat gagaccaata gatgtctcac ttccttctat ctttttatag atgaggttct
     3421 ccttgctgct tttgattggc tgttcttatt acttgatgca ggacagcttt ttcacaatct
     3481 ctccactaaa cggtgttcaa tcagctgacc ctcggtatta gctcaacaaa cggcaaaata
     3541 tgaggaacta tttttccgtt tttttctcta atactcaggt caggacgctg atttcacaac
     3601 ctctcgataa acggtgttca aaagccagtt tctcggtagt aagtcaaatt tatgcaaaaa
     3661 tgtggaaagc cattttcaca aaatttttct tactacttga aactaagcag ctttttcaca
     3721 acctctaata catggtattc cagaagtaac ttcttcgaaa aataagccga aatgtcacaa
     3781 aaatttgaga agcgattttc ccaaattcct tcttatttct tgaagctgac cacttctggc
     3841 acaacctctt accagattcg cactcttttt tctggcgcta gatacatagc gtcttgttcc
     3901 gtgataccaa atgtttcata gaattcgtca aggttttttg gttgcacgtt tgctcggagt
     3961 ttagcagggg catggacatc gatttgcagt aaaagttgtt ggtattcttt ttttgctttt
     4021 gtacgccaaa tcgttgccca attgacaaag aattcctcga tagaaagatc tgattccgtt
     4081 tttgctgctt ccaatgcaca gcttagaccg cctgcatcag caatattttc cgaaacggtt
     4141 aattttccgt ttacttttcc gtcagcaaaa ggcagaccat cgaattcttc gatcattgct
     4201 tgtgctttgt tttgaaattg tgtaagatct tcttctgtcc accagttgtt caagttgcca
     4261 tattcgtcaa ataaagcgcc gttattatca aatgcatggg aaatctcatg agcgataaca
     4321 gctccgattc caccataatt agcagagctt gattgttcta gactgtaaaa tggtgcttga
     4381 aggatcgctg ccggaaagac gatcacattc cgaaatggat gataataagc attgaccgtg
     4441 tcagcactca tttcccattc tgaacgatcc actggtttgt tccatttgct gaaacgatct
     4501 tttaatgtga gtttgctgaa aacaagagta tttgaaagca aagtaccacc ctgatctgca
     4561 ggtactgttt tgaactggtc gaataatgct gggatcttat cggggtagcc tacttggata
     4621 cctaagttat ttaattttat gacggctttt tcttttgttg catccccaag ccagtcattt
     4681 tcttctagac gttttttata aacggcgatc atttttttca ccatttgttc tacgtctttt
     4741 ttagcagctt cgccaaaata tttttttccg tagtaatcgc caactacttg atcgaattgt
     4801 ccagaggcaa ggtaatacgc tgcttttttc tgaggcattg cttcgtctgt tccagacaat
     4861 acgcgagaat agattccgct gacttggcgg aattcttctg atagataacc actaagagaa
     4921 cgtactgttt taatgatcat ccagcttttg aataacggaa aatgagcttc tgtcaggatg
     4981 tcattcaaat gatcgaagta cactggatca gttacgatca ctttatctgg agttgtccca
     5041 atcaaacccg tgacaagttt tttcaagtcc agtttatctg tgtatttaat aaatgtatca
     5101 aaagattgcg gattatacat tttgctgtaa tctgcgtttt cttctgcact ttttacatga
     5161 ggagcaatca atttatcaaa ttgcactgct tgttccgtga ttgcttctgc ctgacttttt
     5221 tctttgccgg caagctctaa taactgaaca gccatatcaa agaaaacgcc tattagttgt
     5281 gcaccgttgg gatggtctga tgcataatac gtcttatctg gaaggaataa agaaggcgga
     5341 taagcaaaga aggcgttcgt ttgcgcattc ttcatatctg catctacatc cagattaaat
     5401 ggcaatggta atgtatccaa cagccattct ggaaattgct tattcaattc gtcgaaagac
     5461 tgcaatgatt caactttttc gattataggt tgaagcggtt gagcatgcaa ctcatttctt
     5521 cggtcataat cgtttgccag ttgataatat gcaaggaaat gtttcatttt ttctgaagac
     5581 actttttctg gatgggcaag cagatcgtct gtttctccca tcaaaagttg gtcgatcccg
     5641 tcaactaaat cttggaaacc gcctgtagct ggtttatctg cagggatttt tgctgttttt
     5701 tgccattctt cattgactgc ttcatagaaa tcttgtttca atcgttcttt gttcattcat
     5761 cgatcgctcc ttttttgttt cgtgtgccca ttatcttaca aaatgaagga attaacaaat
     5821 agaacataaa aaattgaaaa ttcgaacaat caaactgatt tgtttttttc aatccttcac
     5881 ttataatgaa aaaaaggagg cgatcccaac tgaatcaagt agtggataaa cctttatatt
     5941 tcaaagtaga taaaaaaatt aaaaaattag ccagcactca gcagctgcag tcaagaaaaa
     6001 gtaaattgct ttttttagct ctggtttttg aagatcaaag ttatgtgatt atcgatcaat
     6061 caggacatcc ggtagaatat tctccagcaa aatatactta tcaagagggt ctttcttgta
     6121 aaaaatggaa gctgatcaat gaagagccaa tcgagttatc tagatggatc aacagaaaag
     6181 aagatattcc cgttttgatc gaagaaaaaa ggtcaggaaa ggaactcgca aattgctggg
     6241 tgggattgcc agaagaacgt tttttgaggt ataagaaatg ggctaccccc tcaggctatc
     6301 tttgtggtac ttacgcggca gcagttctcc ttgcctatta tcaagactat cgtaaggggt
     6361 ggatgcttcc aaatgagatt cgcaagaaaa atacggctga ttcgttggtt ttgacgaagg
     6421 cattgcgtag ccagatccaa ccactaggac ttcctacgat tccttttcag gttagtacag
     6481 ggatttctag ttttttaaag aagaatggca atcatgagcg tgcacgagca actcttctag
     6541 gttcatggca gcgagctaca aaacgtatac gtgaaggcaa acctgtgatg attggtattt
     6601 tgaaagtact tggcagtaca tatggcaatc attgggtgac agcgtacgct tattttgaaa
     6661 ctgaaacagg agaacgttat tacaaagtac acgacaactg gggcgattat cataaagtca
     6721 ttcctgccag ttggagtaac ggaacagttt cacttcctta agaatttgct gaaattaaca
     6781 gaaaatcttg gaaaaatatg ttaaactatc gaagaataga gaagttttgg ggaggactac
     6841 atgagtaata agtatcagga tgacacgttg aagattttta gtttgaatgg caaccgtcca
     6901 ttagctgaaa aaatcgcgaa agtgttcgga acagaattag gtaaaagcgt cgtgaagcaa
     6961 tttagtgatg gcgagatttc catcaatatc gaagaaagta ttcgagggga tcatgtgtat
     7021 atcgttcaat caacgaatgc acctgtcaat gattactata tggaactact gatcatgatc
     7081 gatgcaatga agcgagcaag tgcgaaaacg atcaatgtcg tattgcctta ctatgggtat
     7141 gctaggcaag accgcacggc gaaacctcat gaaccgatca ctgcgaaatt gatcgctaac
     7201 ttgatcgaag aagcaggggc aactcgagta ctgactttag atctgcacac ggttcaagta
     7261 caaggattct ttgatattcc tgtagataat ttatttacga tgccgttgtt tgctcattat
     7321 taccgtcaat taggtctgac gggagatgac atcgtagttg tttcgccaaa aaacagcggt
     7381 gttcagcgtg cacgtagtct ttcagaatat ttgaacagca cattagccat cgtagatcat
     7441 gcagatgatg cttcaactga gggtggttat gtgatcggtg atgttcaagg aaagacatgt
     7501 atcatggtag atgatatctt gaacacagga gcaacgcttg cacgagcagc aaatgtatta
     7561 aaagaaaacg gcgcaaaaga agtatatgcc tgtgcgtcac atggattatt gtccgatcat
     7621 gcgaaaagta ttttagacaa tgcaccaatc aaagatattt gtatcactga ttctgttttc
     7681 acagaagaaa atcgtcatcc agaaaactta acaatcgtta catgttcaga attaatgggt
     7741 gaagcggtca aacgcatcca tgaaaataca ccgatgagtc cgttattccg tctggaagaa
     7801 aaagaattcg aataaacaaa aaaaagaggg aaagaagttg tgacagaagt gagcagcttc
     7861 aaggagctgc gacaagactt ttgtcacagc tccttttttc tatgcccatg aaacgtcctc
     7921 tagacaaaaa tgagctcttc tttggtttgt tcgctatttt atgctagaat gtgcctagca
     7981 ataatttgga agggatgaat gaagtgaaaa ctatttatct ggatcatgcg gcaactaccc
     8041 ccatgcatcc acaagtaatt gaagcgatga cggcaatcat gcaagacacg tttggaaatc
     8101 cttcaagcat acatggattt ggtcgccacg cgcatgaaaa attggaaaca gcaagacaaa
     8161 tcattgcaga cagtctgcaa gcaaaacctc acgagatcat ctttaacagt gggggaacag
     8221 aaggggataa tacagctatc ttagaaacag cgttctcgcg tcaaaaagaa ggcagacatc
     8281 taatcactac agctatcgaa catcctgctg ttcttaatac catgaaatat ttagagacaa
     8341 aggggtttga cgttacatat ctgcctgtag atgaaaaagg gaatctgtcg atcgaagagg
     8401 tcaaaaaagc gttacgagaa gatacgatct tggtctctgt gatgtacggg aacaatgaaa
     8461 tcggaaattt gatgccaatc aaagaaatcg gtgaactttt agcggatcat ccagcttatt
     8521 tccatacaga tgcggtacaa gcgtacggaa accaaacgat ccatccagaa gaattaggaa
     8581 tcgatttatt aagtatctct gctcataaaa tcaatgggcc aaaaggcgtc ggtttcttat
     8641 ataaacgaga cggagtaaat atccctgcat tgcttttagg cggggagcag gaagaaaagc
     8701 ggcgtgcagg tacagaaaat ttagcaggga tctggggtat ggcaaaagca gttgaactgc
     8761 tgtcacctga agaacgtgaa gcacgtaaca acaaatataa aggattccag caattgattc
     8821 ttgatacatt agaagcaaac gaaatccctt atcaagtaaa tggtgattta acgaataaac
     8881 tccctcatgt gttgaatctt cgcttaattg gcgaagcaaa tgatttgcta ctgatgaagc
     8941 ttgatcttaa tggggtcgct atttctactg gttcagcttg tacagcagga aatatcgagc
     9001 cttcacacgt attagaagca atgtatggag aagatacacc gatactaaaa gaatccatcc
     9061 gtatcagctt tggtttggga aataccgaag acgacatcca gtatttcctt gatcaattag
     9121 ttcgtgctgt caaaaaataa ctagtgaagt cattcttata tgaacagatg tctgagagaa
     9181 cgccttcatt ttttagggaa cttaactgaa aaacctagta aaaatcagga taaactttta
     9241 taataaagag aaactaattt tatcgaggtg aaaatcatgg catttgaaac aacagcaacg
     9301 gtactgggcg caccaattag ctatcgtttg catcctgatg caaaaagata tacattgcgc
     9361 gataatggat ttacagaaac aaacggaggc aattatcaat tgatccgacc attagatgcc
     9421 acgccgcaaa gcaaagaagg attcaaatta aaaatcactg tatcaaaaga tattcaaaca
     9481 ttgaaaatgt cgatcactac agcaaatgga ttgaaagcag tcaatatttt caaagatcca
     9541 aaacagaaaa tgagccaaga taaattttat tttctgatgg atgggatgat tagccgtggg
     9601 ttattcgaaa aagtcgaatg atctgtggat ataaaaagac aactagtttt gaaacggcct
     9661 attgttagat gactaacttt gtaaggacga cgcaaattag ttgtcttttt tatttttaaa
     9721 tttaacacat gttgttattt ttaatatttt gctgatttat tgtttctaag taaagaaatt
     9781 taaattgaaa cgattgttat ttagggaaaa aggtattttt tgaaaaaaga atcccgtata
     9841 atgattgttg tgcaaacgct atacaaaatg aaaaagaaaa gagggatgtt tatggaaaat
     9901 gaacagtcgg tcgttttaac gaattggaag agaaattatt tgttcttttt atcgggacag
     9961 tttttgtcag gaatcactag tatggtcgtc caatatgcga tcatctggta tttgacaaga
    10021 gaaaccggtt cggcgacaat tttgagtttt gctactttac taggaatgat tcccatggtt
    10081 ttactaagcc catttgtagg accgctagtg gatcgctggg ataaaaaagc tcttttgatt
    10141 gtcacggata ttattgtagc gattttcgcg cttattttag cagtagtcgg aacgatttca
    10201 gaatccttcc cgatttggct agtttttgtg tctttgttta tgcgttcggt cgcacaaaca
    10261 ttccaaatgc caacgatcca gtcgattatg ccgacaatcg ttccatcttc tcacataaca
    10321 aggacgaatg gacagttagg aatggtccaa tcagcgaatt tcatcattgc gccagctcta
    10381 ggtgcggctt tgttttcagt cgttcctgtc aattacctta ttttattaga tgtattgggg
    10441 gcagtttttg gtgtcggctt attgattttt gtgaagatcc caaaagtttc tcctgaaata
    10501 ttggaagttc cgcttactat ttttaaagat gcaaaatttg ggctgcagca attgatggat
    10561 aataaagggt tatggtacat aacgatcaat ggtgcatttg tgatgctgtt gttcatgcca
    10621 gcaatcagtc tgtatccatt gatgacgcta gattactttg gtggttccgt tggacaggcg
    10681 ggagcagtgg aagtagtcta cgcagtcgga atgctcttag gcggtgcact gatcagtttt
    10741 ataggaacat ggaaagaccg aatgaaacct attattatag cctacatcat tatgggcctg
    10801 acgatcggtg caagcggatt ggttccaaac gatagtcaag ggttcttgta ctttcttatc
    10861 ttgaatgcag gagcaggttg tgcaacgcca tatttcaata cactgctgat ggcaatgatc
    10921 cagcagagtt atgaatcgaa tgttttaggt cgtgtcttag ggaacttcaa ctctttgatg
    10981 aacctggcag gtccaattgg attattattt gcaggaccat tagctgatcg tttaggggta
    11041 gaaaaaatgt tcttgttttc cggaatcggg attttattat gcggaatcgt tttattttta
    11101 acgtcagctg cccgaaatta tgataaagaa ttacagaaaa aactggtaaa agaacaccat
    11161 gagcaaaaag acgaatagta tggaatggag ttgtgacaga agtcttgtta caactccatt
    11221 tctgatccta atgttcctgt ggcaataagc ctactcaaat gaaaaatatg agtaattatc
    11281 tttatttgtt taatacttga tatagggcag ttttttcacg acctatcgta cttcctcttt
    11341 gcttcataga tttctttgat ttgttgctca gataacggag tgccaaatgg tagtttttcc
    11401 tttaagagtt ctctttccgg tgcgtctacg cctacattga catcgttctc gataggtacg
    11461 ctgtaatgat ggatatgtcc atgaagattg cggatagtgt cgttaggccc gagcaacatc
    11521 ggataatgag tcaagtaata ttgttgatgg tcgaatttaa cgatggcacc tacatcataa
    11581 aaataaaatt tgggacttcc gtcagtaagc ctaggatcat ttttttctaa ataacggaaa
    11641 aaagcgcgac tgtcatggtt ccctttgatc aagtggattg ttccttgcag ttgagtgacc
    11701 agttccaaaa tttctgcatt tgctttttca tattgcggat gcatagcaag gtcgcctaga
    11761 tgataaacat ggtcggtttc ttttattact gcattccagc tagtgatcaa ctgttggttc
    11821 atttcatcca catttgcaaa gagccgcgga gcaaagtcgt tttttcctaa taagcgttca
    11881 tggaaaaagt gcatatcact gataaagtaa ttcatgtatc ttttgcctcc cttttttctt
    11941 agagtaaaca aaatcactta tctgagcaac tcataacatc taaaaagaaa aggttgtaaa
    12001 tgagacgtgc agctttaagc gataagaagc aattttgaaa aatagttttt cacaatttat
    12061 aaaattattc cttattgccg aaaggctggc cctttttatg agtatgccaa ttttttatat
    12121 cgaatgctca aaagatgagt gattttttgg ttgactatca tgtttgtgta ctgaataggt
    12181 ccagtagaac agtattttta cgacttgata attaagggat gaaattttca gaaatatgac
    12241 gtataatgta aaatactgaa aagttgcgac cttcaactcg tagatgtttc agaatctaat
    12301 tgaaatgatg gtgatatcat gacagacaac agcaaaacac gcgttgtcgt agggatgagc
    12361 ggcggtgtcg actcatctgt aacagcactt ttgttaaagg aacaaggata cgacgtgatc
    12421 ggaatattca tgaaaaattg ggatgacacg gacgaaaacg gtgtatgcac ggccacggaa
    12481 gattataagg atgtagcgaa agtagctgct caaatcggga ttccttatta ctctgtgaat
    12541 tttgaaaaag aatattggga tcgtgtattt gaatatttcc tagccgaata ccgcgcagga
    12601 cgtacaccta acccagacgt gatgtgcaac aaagaaatca aattcaaagc attcttggat
    12661 tatgcaatgg atcttggcgc cgattatgta gctactggac attatgcgca agtcactcgc
    12721 gatgaaaacg gcgtggtcca catgcttcgt ggagtagaca ataataaaga tcaaacttac
    12781 ttccttagcc aattatcaca agaacagctt tcaaaaacga tgttccctct aggcggcatg
    12841 gaaaaatcag aagtacgggc aattgctgaa cgcgcaggcc ttgcgactgc taagaaaaaa
    12901 gattcaacgg gaatctgctt tattggtgaa aagaacttca aacaattttt gagcaactat
    12961 ctgccagcaa aaaaaggaaa tatggtcact cttgatggtg aagtcaaagg acaacatgct
    13021 ggcttgatgt attatacgat tggtcaacgt caaggactag ggatcggtgg cggaggagat
    13081 tcgcaagaac cctggtttgt tgtaggaaaa gatctagcga caaacacatt atatgtgggg
    13141 caagggttcc atcatcctgc attgtatgcc acaagcttgg atgcaagtga aatccacttt
    13201 acgacgaatg aaccaatgcc aaaagaattc aagtgtacag cgaaattccg ttatcgtcag
    13261 caagacgttc ctgtgacagt tcgcttattg gatgataatc gtgcagaagt cgtattcgac
    13321 gaacctgtac gtgcaatcac tcctggacaa gcagttgtat tttatgatgg aatggaatgt
    13381 ctgggtggtg gtttgatcga ccacgcatat caagaaacaa aagttttaca atacgtttaa
    13441 gcgatattaa atgaatcaaa acagctatgg ctaacaaaag aaacaccttt tcttttggat
    13501 agcatagctg tttttttgca ataaaattaa tttttattca ttttatactt gaaata
//
LOCUS       DADVXB010000076        13375 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.077, whole genome shotgun sequence.
ACCESSION   DADVXB010000076 DADVXB010000000
VERSION     DADVXB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.077"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            172..966
                     /locus_tag="KB902_001726"
     CDS             172..966
                     /locus_tag="KB902_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808552.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            956..2998
                     /locus_tag="KB902_001727"
     CDS             956..2998
                     /locus_tag="KB902_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808553.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            3279..3428
                     /locus_tag="KB902_001728"
     CDS             3279..3428
                     /locus_tag="KB902_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBB6808554.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            3439..4953
                     /gene="dltA"
                     /locus_tag="KB902_001729"
     CDS             3439..4953
                     /gene="dltA"
                     /locus_tag="KB902_001729"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBB6808555.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            4950..6155
                     /gene="dltB"
                     /locus_tag="KB902_001730"
     CDS             4950..6155
                     /gene="dltB"
                     /locus_tag="KB902_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBB6808556.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            6200..6433
                     /gene="dltC"
                     /locus_tag="KB902_001731"
     CDS             6200..6433
                     /gene="dltC"
                     /locus_tag="KB902_001731"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBB6808557.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            6436..7704
                     /gene="dltD"
                     /locus_tag="KB902_001732"
     CDS             6436..7704
                     /gene="dltD"
                     /locus_tag="KB902_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBB6808558.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            7845..8927
                     /locus_tag="KB902_001733"
     CDS             7845..8927
                     /locus_tag="KB902_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBB6808559.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            8927..9730
                     /locus_tag="KB902_001734"
     CDS             8927..9730
                     /locus_tag="KB902_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6808560.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            9800..10540
                     /locus_tag="KB902_001735"
     CDS             9800..10540
                     /locus_tag="KB902_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6808561.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            10551..11555
                     /locus_tag="KB902_001736"
     CDS             10551..11555
                     /locus_tag="KB902_001736"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBB6808562.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(11600..13297)
                     /locus_tag="KB902_001737"
     CDS             complement(11600..13297)
                     /locus_tag="KB902_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808563.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         4302 a         2189 c         2703 g         4181 t
ORIGIN      
        1 atattttatt gtgaaaaaag gtgaaaactt gtagctggtg gatttgtttt ttgcatattt
       61 aattttgctg aataaaataa ttgaataaaa ttttttattc agtccaagta aaagtgacaa
      121 aaacataaga gcaaattatt cgtagatatg ctactatgca aataaataga aatgaaaaat
      181 gaaagaggag gagaagaatt ggaaaagatg atcgaagtga aacatctaag taaaagctac
      241 ggcagcaaac tttctcccgt caaagcctta gataatatct cattcacagt agaagaaggc
      301 gagtttgttg ggattatggg cccaagtggt gcaggaaaga caacgctgat gaatatcttg
      361 tccacgatca atttgcctac gatgggcagt gtctcgatcc aaggaaaaga aatcacaaaa
      421 atgaaaaaca gtgagctcag tgactttcgt cgaaaaaaac taggattcat ttttcaagag
      481 ttcaatttga tcgataccct aaatgcaaaa gacaatatcc tattgcccct agcagttgaa
      541 cggatgacta aagaggaaat ggaaaagaga gtaagacatg tagctcaatt gttgaatata
      601 gaagaactgc tcaaacggta tcccgatgaa ctttctgtcg gacagagaca acgaattgca
      661 gctgctagag cacttgttgt tcagccacaa gtgatttttg cagatgaacc aactggctct
      721 ttggactcga agtcggctac agaattgttg aactacttga agaccatgaa tcaaaaagaa
      781 aaagcaacga tactgttagt cacccatgat ccatatacag caagctactg cgatagaatt
      841 ttatttatta aagatggtgt gattttttct gaagttgtca gaagagggac aagaagagag
      901 ttctttgaga aagtaataga catgcaggcg acgattggcg gaggaggaaa aatgaatgct
      961 gtataaacta gccgttaaaa gtttttttcg gcagtcacga ggctatcttg tttatttttt
     1021 cagtttgact ttatccgtaa tgatctatta ttccttcagc gcaatgacct acgatcaatc
     1081 tttagtcaga agagcaagtc aagatacttc gatagatggt ggattgagtt ttggtggatt
     1141 tatcattact gttgttttgc tttttttcgt attcagtgcc aaccgatttt tcttgaatag
     1201 aaggcaaaag gaaataggca tctatcagct ttttggtatg aataaactgc agatatcagg
     1261 tatatatgtg ttagaaatca tgataattgg attgttcgcc tgtatttctg ggatattact
     1321 cggtattatt ttttccaaac tcttttcaat gattttggtt cgaatgatgg atatggatct
     1381 tactagtcca ttttttatct ccattccatc agtagtagat actttatttg cttttttcat
     1441 catcctttta gcagtatctg tatattcaat atggaaaata tggcgctatc caatgattcg
     1501 aagttttgga gaaaaagaac aagcagatag ttcaacaatg cgcttcagga caaggcaccg
     1561 attactcgca gtcatcgggt tactactttt aacgagcgga tattttggag ctagtcattt
     1621 tagggaaatc acttcatgga tgatcagtta tcattatctt gatacattag ttttcttttt
     1681 tcctttttta atttttttcg tttgtgtggt cggtacttat ttgtttttct gttatacatt
     1741 tcggttattt ttgatcatat tgagtaaatg gaagatttat tactatggta tcaatttttt
     1801 gataatgggt aacacgcaag ttcatttgct caaaagttgg cgtacaaatt ctctgattac
     1861 agtcattctc ggaatttctt taatgacaat tggcggcacg gctagtatct ctactatttt
     1921 atcctaccag gagaaagttt cctccccgat ggactatcag tttgatgttg agacagagaa
     1981 aaaaatcaag ccgattctag cagaggaagg gcagaagata actaaagaaa tcaccttgca
     2041 ttataaagtc attgggagta tctatagtca aaatctcgaa gaacctatgt ttcaaactgc
     2101 taatctgatc acggaaacac aatatcaagc cttcagaaaa gttaatccag atttgccgaa
     2161 catttctttg aaatcacctg gtcatactgt tttgcttgat caaatgcaaa ctctttttcg
     2221 gaatatttca ttatatggat ctagtattgg actgccagat aatcaagaat tgaagattca
     2281 acaaatgctt ccaagtgtat taggtgacga aacaatggta tatctaagtc ctgtactgat
     2341 tgtagatgat accgtttttg aaaaagcaaa aggtgtggat tatcaagtag tcaatgtaga
     2401 tgtatcaggt ggaaataatg aaaaaataga tgaacgactg agcaatgacc tgtcgataaa
     2461 gtggctcaat gctgtttatt attcttatga tatcgtaaat ggaagtctac aaggagaaat
     2521 tagcacaaag aaacttccgg atgaccaaat gaaggaagca caatttagcc aagaaagctc
     2581 tcgtttgaat ttctcttcca gctattcgaa attgcgtgca gttaatcggc gaatcggtat
     2641 caatattttt gtcacactat ttgtcgggat gatcgtgatt attgctactg gtagtatttt
     2701 gacagtccgg caattagcag aagcagagga agaaaaagaa aattatcacc tattgactaa
     2761 gctggggatt ccacaaagaa ggatcagacg gatgatcttc gagcaaaacg cacttacctt
     2821 ctttccaccc atgatattag ggatcactca cgcagtattt gcaatcaatg tcttcactca
     2881 gtatataaaa actgccgatt actggttggc ttatcttgtg agtggcttat tgatccttat
     2941 ctatcttttg ctttatgtca ttacgagtca gttatattgt cggattatcg aggaatgata
     3001 tacggaataa gacaagataa taaatagaac taaattttga ataccattta tttggaataa
     3061 gaggttgtga cacgattttt gtcacaacct ctttattttt tatatttttt aaaagtacga
     3121 gaaattataa agaaaaaagc agtgatttga tgtgctattt ttataaaagc tatgtgacaa
     3181 aactgttagt aaaaaaacgg tttctgtaag ctagacacat gtttcttttt gtcaaaatta
     3241 gttacacttt gtgtgaggtt atatgaggag ggaatccaat gaacaaatgg cgttctaatc
     3301 caaaattgaa ttattgggga aaattcatca ttcgaacaat tttttatagt gcagtactgc
     3361 tgttcctgat ttatctgtat cactataaaa atattcaagg aggaactttt atctataacg
     3421 aattttagga ggaagagtat ggaaatcaaa acgattattg aagcaatcga tgattgggga
     3481 ataaatgaac ctgatcgagt tgcttatcag gcggatgaga cgcatacttt tggtgaattg
     3541 aaacaagcat cagacgcact tgcttattat ttagaaaaaa aggtagaagg cgatggacca
     3601 attgtcgttt ttggcaattt ggagtttgaa atgattgtct catttctagg ggttgtcaaa
     3661 tctggccatg cctatttgcc gattgaagag catacaccca aggagcgtat cctatcgatc
     3721 tttcgggtgg ctaaaccatc tatggtcatc agtatcgggg actggataga agatattcct
     3781 tcggttcctg tcataacaaa aaaagaattt caagaaatca agaagatacc agtaggattt
     3841 tatcccagaa atagcgtaaa aggtacagaa aatttttata ttatttttac ttctggtact
     3901 actggagaac caaaaggcgt acaaatcagt catgataatc tagtcagctt tgttcaatgg
     3961 acgatggaag actttgggat caagcctggt atgcatttct tagcccaagc gccattttct
     4021 tttgatttat cggtattttc tatttatcct gcattagttt ctggcggaat gctgaagccg
     4081 ttaaataaag cagttgttca agactttcgt caattattcg cgacattgcc agccttgaag
     4141 ttgaatgtgt gggtttctac tccatcattt atggatattt gcttgatgga acctacattc
     4201 aatggagaaa atgtgccgga attggacatg tttttatttt gcggagaaga attgacgaaa
     4261 aaaactgcag aaagtctact tgatcgattc ccaaatgcac ggatatataa tacttacggt
     4321 ccaacagaag caactgtagc tatttcaagt attcagattg accagcatgt actagatagt
     4381 tatgaccgac taccgattgg ctacgtaaaa aaagacacga aagtttctat tgtccaagaa
     4441 ggtaaacctg tttcaaaagg agaaacgggt gaaatcatta ttgcaggacc aagcgtatca
     4501 aaaggttacc tgaacaatcc cgaaaagaca gctgctgcgt tcttttgtca aaatgactta
     4561 gcaagttacc atacagggga tgcaggtaga ctagatgaat atgggctttt attttatgaa
     4621 ggacgtatgg atcagcaggt caaattacat ggataccgga ttgaactcgg ggatatcgaa
     4681 cattatctgc tccaagacaa ccgaatcaaa caagctgtcg tcgtaccaaa ataccaagga
     4741 acaaaagtac agcagctggt tgcttttgtc gtattagaaa acaaaacgaa acagccggat
     4801 tttcagttga ctaaatctat caaagaacaa ttactagaag ttgtaatgga ttatatgatt
     4861 cctcagaagt tccattatgt cgatctgctg cctcagacag ttaatggaaa aatcgatcga
     4921 aaaaaattaa cagctgaggt gaatcctgaa tgatgttacc tcatatgatc ccttatgcag
     4981 agccgtttta tttttttctt ttagccattg cgcttgtacc gatcgttcta tctttattga
     5041 tatgggaaaa aagattacca gtttatcaat cagcagtgac acttttcttt ttatttgtca
     5101 gctttggagg taattattgg caacagggag cggcgctgat tgggtatgtt ttgtggcaga
     5161 cgatacttgt atggggctat tttgtttatc ggcaaaggaa aaatcagaca ggatggtttt
     5221 ttgccgccgt tattttagcg ataattccac tgtttttaac gaaagtgact cctttttttg
     5281 aacatggaaa agcatcgtta cttggttttt taggaatctc ttatttaacc tttaaatctg
     5341 tacaaatgat catggaaata agagatggca tgatcaaaac atataagcca tttcgttata
     5401 tccagtttct gctgttcttt ccaacaatct cttctggacc aatcgatcgc tataggagat
     5461 ttgaaaaaga tcagctccat ccgcctgttc gtgataaata tgttgatctt ttgggaaaag
     5521 gcgtccaaaa tatttttgtc ggttttttat ataaattcat tatcggttat tattttggtc
     5581 aagtactgct tcctgtagtg ggacgcattg ccttacagca tggtggtatt tcatgggcat
     5641 tagtaggtta tatgtacgtg tacagtatgt atttgttttt tgattttgct ggctatagct
     5701 tatttgcagt cggtacaagc tacatgatgg gatatcagac accaatcaat ttcaataaac
     5761 cttttttatc atggaatatc aaagaattct ggaatcgttg gcatatgacg ctgtcctttt
     5821 ggttccgtga ttatgtatat atgcgattga tgttcttcat gatgaagaaa aaatttttta
     5881 aaagcaagat cgtaatgtca aatatcggtt attttgcttt gtttcttcta atgggtatat
     5941 ggcatggatt gacgtggtac tacatcgtat atggactgta tcatgcttgt ctgatctgtc
     6001 tgacagatgc atggatccga tttaagaaga agcataaaga gcagttgcct tctaacaaat
     6061 ttacgcatgg cttagccgta tttttgacat ttcaagcagt atgttttagc ttcctgattt
     6121 tttcaggatt tttagataaa ctttttttta gctaacgaat agtgacatat taatttatat
     6181 aacaaaggag aaaaggaaaa tggaagaaca aattttatca atcttagaag aaataacagg
     6241 aacagatgaa gtaagaaaaa atcgtgatat tgatctattt gatgaagggt tgcttgattc
     6301 tttagcatct gttcaattat tagtcgagct agacggagag ctggatatcc aagtccctgt
     6361 atctgaattc gagcgagagg attggagcac accgaataaa atcattcaac aagcaactgc
     6421 attgaagggt tgagtatgaa aaagaaactt tttgctattt tcggcccggt tgttttagct
     6481 gttggcttac tgtttgtgtt ttttacctcc tcctatcaag tagatatctc taatccagaa
     6541 acgattagac gtgcctcttc ttccatgtca gtgaacgtgt tgaaaggaga tgcgataaaa
     6601 aattatgcat tatctgaaaa acaatatatt cctttttttg gctcaagtga attaagcaga
     6661 atcagtccat ttcatccgtc tgttctggca gaaaaatacc agcgaaacta tcgtccattt
     6721 ttgctgggag cacccgggac acaatcgtta agccaatata tgatgatgcg ttctgcagga
     6781 gatgctatga aaaacaagaa agtcgtcttt attatttctc ctcagtggtt cgttaaaaat
     6841 ggtgtaaaaa ctgattactt taatacgtat tattctgaac ttcaaacata cgactggttg
     6901 ttttcaatga agaaagtaac gcctgctgat cgctatttag ctagaagatt attaactttc
     6961 tcaaaagtaa aagagaatga tacgttgacg gcgattctgc aaacgatcaa aaaagggaag
     7021 ctacctttac ctgaatcttt gaatcagctg cgcagccaat ggaacatgct gaagagagag
     7081 gatgaagtat tcagcaatat tgggttgaaa gatcgacagc aaaaaatcga tcatgagtca
     7141 aaacgattac caaaacaata ccaagaaaca gaattatcca ttttagcaaa tcaaattgga
     7201 gaacgagaaa cgacgaataa tccattcggg ttgaaaaacg atttttatac gcatcgtatc
     7261 cgagcccacg agccagagct caaacagtca caaaaaaatt gggattatcg tttttcgcca
     7321 gaattttctg attttcagct ggtcttggat caattagcaa aaaaccataa cgaagtattg
     7381 ttcatcatcc caccggttaa cgagaaatgg agcgattata ccggactatc tcaagaaatg
     7441 ttacaaggat ttgccaaaaa gatcaaattt caattaaata gccaaggatt caatcgaata
     7501 gctgattttg tcaatcaagc gggtaccaac tattttatgg aagacacgat ccatctaggc
     7561 tggaaaggct ggttggctgc agatcaacag atcagaccgt ttttagaaga aaatcatatt
     7621 actgctagta agtatcatct tgacgatgct ttttttagca aatcttggca acatcaaata
     7681 ccagataaac tacaattaaa ataaagaaaa caggcgagtg ttgctcgctt gttttcttta
     7741 tttttgaata ttctgaataa aagataaaaa taccaagttt gcctgaacaa aaatcataag
     7801 caatggtata atcacaatat gaatatagaa atgggggaaa acatttggat acaaaagaag
     7861 aacagctact tattgattta acttctgcaa aaggagtacc tggaaatgaa gaagaggtaa
     7921 gagaagtatt cagagaatat gccaaaccat tcgctgatga tattttttat gacggtttag
     7981 gcagtgtgat tgccaaacat ggtgctggcg gaggccccaa ggtctttatt tctggacata
     8041 tggacgaagt tggttttatg gtaacaaaaa taaccgaaaa aggattcttg gaattccaaa
     8101 ctcttggagg ttggtggggg caagtcatgc ttgctcagca agttgaaatc aaaacacgtg
     8161 aagggaaaat cgtccacggt gtgattggtt ccaaaccacc acatgtttta acacctcaag
     8221 taagaaataa accttatgaa ataaaggata tgttcattga tattggcgca tcaagccaag
     8281 aagaagccaa agagtggggc atacgtcctg gagatatggt cactccatat attgaataca
     8341 aacgaatgaa tggcagtaaa tatttactgg caaaagcatg ggataatcgt atcgggacag
     8401 ctgtttctct gcgagtatta gagaatctat ctaaagaagc acacccaaat gttttattcg
     8461 caggaagcga tgtgcaagaa gaagtaggct tgcgaggtgc tcgaacaagt acacaccttg
     8521 taaatcccga tattgctttt gctttagata ctggtacagc aggagacact ccaggaatga
     8581 caccaaaaga agcagattcg attttaggaa aaggcccaca gattttgatt tttgatgcat
     8641 ctatgatccc gcataaaaaa ttattgaatt ttgttattga tgtagcagag gaaatggata
     8701 ttccattcca atatacagtg atttctggcg gaggaactga tgcaggacaa atgcatttga
     8761 caagagatgg tgttccgtct gtagccatta ccgttcctgt tcgttatctg cattcccata
     8821 catcagtgat tcatgaagat gattatttga atacagtgaa actagtcaca gaattagtga
     8881 aacggcttga tagtgaaaca gttgaaaaaa ttcggagtta tgaataatga ataatagaat
     8941 acctatttct gaatatcgga aaaaagcacg agtttctttg gaaaatcaat ggggaatcaa
     9001 tacttggctt gttttcttat ctataatatt tacgagcgtc atccagaact tttttgacgg
     9061 tttcagtcct tttccggaag aaagcatgca gcagcactta ttgagttttc tagtcgataa
     9121 tttactttta ttcgcattca actatgcatt gttttacatt gcgctagtag ttgtacgggg
     9181 tggcagacca aaaagtaacc ttttattttc agttttccaa agaaagtatt ttggttcgat
     9241 acttggcatc aatttgatca attcagtcat caactggcta ctcaacagtt taatctttct
     9301 gcccatgttt ttaatcagcg gagtgagtac ttatatgcag ctgcttttca gttcaaatgc
     9361 ggtacctacg ggtgtcatgc cagaagattt tcttgatatc agctttgttt tatcgatgat
     9421 agggatgatt tttgtttcag cactcatcat gagtattgtt ggcggtttat tccaatttgc
     9481 tgcatggaca aagttcgact atcctgattt gtcggttatt caatgtttga aatatggctg
     9541 gtttttattg aaagatagaa ttggtacgta tattttgttg cagctgtctt ttatcggctg
     9601 gtatttgcta ggagcaatcg ctttgttcat cggtcttttg tgggtcattg tttatgtgaa
     9661 tgtgtcagtt gcagaatttt atgaacaagc acggattgaa aaaggaggtc cagacgccta
     9721 ttttacttag catgtaagca gtttattcat caaaaaaata acttttgtgg taggataaat
     9781 ctttgagggg gaatgtacga tgaaattaac tgttttagga tgcttaggag cgtatcctta
     9841 taaaaatcaa gggacaacag gttatttgct tcaatctgac gggttcaatt tgttgatcga
     9901 tgcaggtagt gctacgctga tcaaattaca agaacacctt gatccacttg atctagatgc
     9961 tgtgatcctt agccattatc atcatgatca tattgctgac cttggtgtat tacagtatta
    10021 ctggcaactt catcctaaga gaaatccgga gacattgctt tcaatttatg gacacacaaa
    10081 agattccatt cactttgaag aattgacgtt ggaaaatgtc tcaaaaggac atccttattt
    10141 tgaagctgaa gaattaaaaa ttggtccttt tctgattact tttatggaaa caatccatcc
    10201 agtagtatgt tacgccatgc gtatcgtaga agaaacaacg gggaaagtat tcgtatttac
    10261 aggtgattca ggttatttgg aaagtttcgc tgattttgcg aaagatgctg atttgtttct
    10321 agcagatacc tatctttttg aaggaaatga acatcatcat gcccatttca cttcaaaaga
    10381 agctggagaa cttgcgaaat cagctaacgt aaagaaactt gtacttacac acctacctca
    10441 gtttggtgat ttagaacaat tgaaaaatga agcgcaaaag gcagcaggca aagggattga
    10501 tatagaactt gctgcagttg acaaagtgtt taacatttag gaggaagaac atgatttttg
    10561 taccaaatga aaaccacgac ccaagaatca atttagcaat tgaacaatat ttgctgcaag
    10621 aaatgccttt agatgaacct attttgctct tttatatcaa tgaaccttca atcatcatcg
    10681 gcagaaacca aaatacgctt gaagaaatca atcgagatta tgtggaagaa aatggcattc
    10741 atgttgtccg tcgcttaagt ggagggggag ctgtctacca tgattttgga aacctgaact
    10801 ttagttttat catgcctgat gatggggatt cattccgtga ctttgcgaaa gtaacacagc
    10861 caatcatcca agcacttcat gaattgggtg ttgctggggc ggaattgaaa ggccgaaatg
    10921 atctagtcat tgatggcatg aaattttctg gcaacgcgat gtatgctacc aacggtcgga
    10981 tgtttgctca tggaacaatt atgttcgact ctgatatcaa tgaagtagtc aatgcattaa
    11041 aagtaaaaaa agacaaaatc gaatcaaaag gaatcaaatc gatccgttct cgtgtaacga
    11101 atatcaaacc atttcttcca gaagaaaagc aaaaaatgac aacagaagaa tttcgtcaag
    11161 aaatcttgtt gaaaattttc ggcgtagagt cagtagaaga agtaaaaacg tacgaattga
    11221 ctgatgaaga ttggaaaaaa atcaatcgaa tctctgagga atattatcga aattgggatt
    11281 ggaattacgg gaagtctcca gatttcaatt tctctcgcca aaaacgtttt tctatcggtt
    11341 cgattgaagt ccatttgaat gtctcagaag gaatgatcaa agaagcaaaa atctttggcg
    11401 atttcttcgg actaggagat atctctgacg tggaaaaaaa attggttgga cagaaatatg
    11461 ataaagcatc tctatcaaaa atagtcagcc aaattgatgt gaagaaatat tttggtgcga
    11521 tagaaccaga agaattgctt accttacttt attgaaaata aaaaatagcg gaatccacat
    11581 atatggattc cgctattttt tatacaggat tcgggtaatt tcgagagagt tgaacagtga
    11641 tccgatcaat gaaagtatct ttttcctgcg ttagtgttcc tgtgtaacga tccgctacgt
    11701 ctttcatcat cattaagtca aaacgttcct gatcatctaa ttcttctgtg atgcctcgac
    11761 taaataggtt tgtatcgtaa tgtgcactat gttcgcaaca aatgacgaaa tgttcctctt
    11821 gttcgtgtat cgacaaataa atttttcgat acagtggatt ttcgatggca tgagtttctc
    11881 taaaggaatg ctctaaagcg tggatcaaaa gttgagccag atcgtcatcg ttgataggaa
    11941 gttcttcggg aagatctgct tggaaggtta tctgaatatt ccgtttggca gctaacttct
    12001 ggtaacgcgc taagataaga tttgtcacct ggtggttgca aaaagaacac agcatttcga
    12061 aattttttgc ttcttctaat atcttttcca catagttttt agcttttgtt tggtccgtat
    12121 gcattaaatc ttgcagattc tccatctctt ggacaaattc caggcgaagt gtatttactt
    12181 cttggatatg ctgtcgaagc tgctcataat gttgctccaa caaatcattt ttgattttta
    12241 agaaatctac ttgtctccga tctttgtcgg tatttaagat gtgatcgatt agattgtagc
    12301 tgataataac gattagaatg ataatatata aaatcgtaga ccaattgatc gttgtttgat
    12361 agatacctaa tgccgtttgg atgtaaatca agcaatggat aatggctacc aagacgatcc
    12421 aaggtgtaca agctacataa aaacggttat tcttatatgc ttcgccaatg catgcaagtg
    12481 aagtgactaa agtgcttata acactagcaa tattagcaat cggcattaat tcaggaagtt
    12541 ctgcaggagt aaaagttgca taaagcagaa cgccgataaa aatcaaaagt tggaacgtac
    12601 aaaaaattcc gtaccatttt ttatagtaaa acattcggct ccaatagtag cagatgatga
    12661 aagctgacgt taagataata aataaatgag ataaaaaaga atgaacgaat ggttcaaaaa
    12721 gaataccact taaaatatct tctgatacag cttcaaatcc taatgccaaa gcaaagcaac
    12781 ttaagagaat aagtgagtat tcaagacgtt tttgtttata catcaagtag atcgtataga
    12841 aaaaggtccc tatagcgata aaaacagcga ttatcatcgt caatacttgc ggcactgatt
    12901 gtgaataaat aaaactaatc aatggtccag ttgttcctag ataaactttc ggtggcagtc
    12961 cagcatagtt ctgataagga gatgagactg taagggtcaa tttttttccg atataatttg
    13021 ctggtaaatc tatcacagcc aatgagagtc cgggattgct ttcttcctga taatctttcc
    13081 gttggtataa aatcttttcg cctagatata cagtaatcca ttgatggttt cctttgatta
    13141 gtaaatttgc ttcgtccaac ggtttttcaa gtgtcgtttc cataatgaat gtttcgtctt
    13201 tatccacggt aggaatcgta cgagtgtact tgctgtcaaa cttaaaatca ggatcatctt
    13261 ttgtatagaa aacccacgaa tcttttattt ctttcatttg attgctgtcc gcaggagaaa
    13321 aaataaaata aaagaaataa gcaattcctg ttaaaaataa caatgataat ataat
//
LOCUS       DADVXB010000077        13132 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.078, whole genome shotgun sequence.
ACCESSION   DADVXB010000077 DADVXB010000000
VERSION     DADVXB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.078"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(301..915)
                     /locus_tag="KB902_001738"
     CDS             complement(301..915)
                     /locus_tag="KB902_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6808564.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1521..1898)
                     /locus_tag="KB902_001739"
     CDS             complement(1521..1898)
                     /locus_tag="KB902_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808565.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2198..3079)
                     /gene="galU"
                     /locus_tag="KB902_001740"
     CDS             complement(2198..3079)
                     /gene="galU"
                     /locus_tag="KB902_001740"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6808566.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3122..4141)
                     /locus_tag="KB902_001741"
     CDS             complement(3122..4141)
                     /locus_tag="KB902_001741"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6808567.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4774..5778)
                     /locus_tag="KB902_001742"
     CDS             complement(4774..5778)
                     /locus_tag="KB902_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6808568.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5791..6840)
                     /locus_tag="KB902_001743"
     CDS             complement(5791..6840)
                     /locus_tag="KB902_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6808569.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(6857..7678)
                     /locus_tag="KB902_001744"
     CDS             complement(6857..7678)
                     /locus_tag="KB902_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6808570.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7665..8444)
                     /locus_tag="KB902_001745"
     CDS             complement(7665..8444)
                     /locus_tag="KB902_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6808571.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8461..8931)
                     /locus_tag="KB902_001746"
     CDS             complement(8461..8931)
                     /locus_tag="KB902_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808572.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(8943..9362)
                     /locus_tag="KB902_001747"
     CDS             complement(8943..9362)
                     /locus_tag="KB902_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBB6808573.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9443..12220)
                     /locus_tag="KB902_001748"
     CDS             complement(9443..12220)
                     /locus_tag="KB902_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6808574.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12411..12635
                     /locus_tag="KB902_001749"
     CDS             12411..12635
                     /locus_tag="KB902_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808575.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT         3860 a         2743 c         2131 g         4398 t
ORIGIN      
        1 gtgtattaag agacaagaaa gaatccatat ggattctttc ttgtctcttt ttccactact
       61 ttttattttt ctgacactac atattcttat aactcatttc tcataactgt gaaacaactt
      121 ataaaaataa caaactttaa acaaaacaag cttaaaatca aagatgatcc atcttaaaat
      181 aactaaaaca aaaaaagtag tcgttgttaa tcctcattaa taatcgtttt ctttttttca
      241 aacgctccat ttttatgtgg aacattattt ttttaaggaa ctttgtcaac atgtggataa
      301 ctattttcca cttgtgtcct ggactagctg ttttgctgta aaatacaaaa cttgctgcag
      361 caaaaagatc gttgcaagag aggctgttcc gcagatcgct ggatctagat ttggcaaagt
      421 caagactgca tcatgtaaat tggcgtggtt gtccaaaacc aaatcagcaa attcaaataa
      481 tcgcaaacca ctgctatgtt gcgatttgat acttcgtgac aaatcaaatc cagtaacaat
      541 gattaatgga tgaccatttt ctttgatcca ctgagctagt tcgatgattg ccgggtttct
      601 tccttcattc gaaagaagaa gaaaaatgtc ttctgatttg acagaaagct gatcaataat
      661 tgcctgtcct gcaccttcta gcgtttcata gacacctccg gctggatttt caatcaatat
      721 acttggtaca agatccgggg tttgatccca aaattcaaat gctacaccac ttagtgtgcg
      781 gctagcatat atctgcaatc taccaccttg attaatttgt ttcgcgatcc aagtgccagc
      841 ttgaagcatc agcggctctt ctatccttaa tttctcttcc aattggtgat aatagtcaaa
      901 ataacataaa ctcatttatc tctcccgcct agctatactt gacatgaata gaaacagctg
      961 cctaatctaa ggaagtacat aaaaaaacag tagttagaca gtaacacatg tggtctttgc
     1021 tgtttcaaac acaaaaaagg cattgaacga atacgcccaa taccttgaca tagcaaataa
     1081 aacaacgtgc agaccattga aaatatctac ataggggtag aattttcacc ctagattagg
     1141 tacaataaat taggtcgatg cactgcattg actatggcaa aatgatcggt cagggtgtat
     1201 gtgtgtgact ggtcattccc tgattcttag cgccaactaa gggtcaggga gccttttttt
     1261 attcagctgt ttctatctga atttattgta agtaatctct tatccaagtg caagcaagaa
     1321 aatacaaaaa aacattggta tgatttatat atatataaat aacataaaaa aaggaatggc
     1381 ttatcccgat acaacaagca ttcctttaaa aaagattctt ttatataagt gaaaaaagct
     1441 tttttccacc aattaaataa atctctcatc tcaatagttt atccattatt ttatcttttt
     1501 ttgcgtatac ctactaaata ttaccgtctt cttctcgttc ttctactttg ttcgagagaa
     1561 tctgtactag aaaaagtagt tgtatgtcta ccttttctgc ctatccgaga ctttcttttc
     1621 atatatggga tataaatgat tagatacagt acagcaaaaa ataaagcaaa tacgcaagct
     1681 tcccaactac ctaacgccaa ttcaaccatc aaggtagcaa ccccaacgga tgctgcatac
     1741 cagataaaaa tcagaaacgt ttcttttttt ctgaccatgc gaaacatgat aaatagacta
     1801 ataagcaata gtggcaacac aaatatccaa ttgcttcctt ccatcagcca cttgagtata
     1861 tcaagcagcg actgtgcaac agcgactaat tttcccatag tgaacacaca ccttttttta
     1921 taattaaaaa attcgccttt ttattctact atgaatcttc tggcttggct ttcatttctc
     1981 ttatgtaatc attttctttt atacaactta aaaaaaaatt aaaccattag cataatattt
     2041 tctgaatcta ttcacgaaag tctttttcta tctttcgttt tccacgactc aactgatcta
     2101 gagtcaaaaa actaaaacga cagttgcgca aatgacgcac aagctgccgc tttaataaca
     2161 aatagccttt cattctcagc aggccactta tttccagtta actttctgtt cttagctttt
     2221 tactcaactg gataatatat gcacttaatg aagtcccaat ttccgaatgt tgaagtccat
     2281 attcaatatt tgtcttcata tatcctaact tatcgcctac gtcgtatctt tttcctttaa
     2341 actctctcgc atagaccgcc tctgtctggt taagagtctg aagtgcatcc gttagctgta
     2401 tctcgtttcc tgctcctggt tcttgagttt ctaatatctc aaatatttta ggagtcagta
     2461 gataacgtcc gataatggct aaattacttg gtgcttttcc catttcaggt ttttctacaa
     2521 acccttttac tctgcaacga cccttttcgc tatctgtttt aggatcaata attccgtatt
     2581 tagatgtttc attttctggt acacgcatga cggcaacagc ggaagcttgt gtttcttcat
     2641 aatccatcat caattgttga gtcaatggga tatcatcttt catcaaatca tcccccagca
     2701 tgacgacaaa cggttcattt cctataaatg cttttgcttg aagcacggca tcccccagtc
     2761 ctcttggatg agattgacgg atgaagtgaa gattgacttg agtcgtttct tcaactaaag
     2821 cgagtaattc tgttttttcc ttttcccgca aattgttttc caattcgata tttgcatcaa
     2881 agtgatcttc aatgggtctt ttttcttttc ccgttacgat caagatgtct tcgattcccg
     2941 aatccaatgc ttcttccaca ataaactgga tcgttggttt atccacgatt ggaagcattt
     3001 cttttgccat ggcttttgtt gccggcaaaa aacgtgttcc tagcccagcg gcaggaatga
     3061 ctgctttttt gaccttcact tgctgttcct cctaaacgac gattaactat tgatcatcta
     3121 tttaacgaag agaaaattca ttctccattt ttccgtcacg taacatgatt tcttttgctg
     3181 cttttttgat atcttctcca ttatacaaaa cattatagat tgtttgagta attggcatct
     3241 caacacctag ctgttgagct agctctactg ctgcttttgt cgttgccaca ccctcaacga
     3301 ccattcccat gttttctaga acttcttcca gcttatgtcc ctgtcctaac aagttaccgg
     3361 cacgccaatt gcgagaatga acacttgtac aagtaacgat caagtccccc acaccactca
     3421 aaccgataaa tgtcagagga ttggcaccca tcgcgacacc aagacggctg atttctgcca
     3481 atcctcgagt catgattgct gcttttgcat catctccgaa tcctaatcca tggatagcgc
     3541 cggcaccaat tgcaatgata tttttcagtg ctgcaccagt ttctacgcca atcacatcat
     3601 tatttgtata aatcctgaaa taatcattca tgaacagttt ttgtacatag gctgctgctt
     3661 tttgatcaat acttgcagct gtaattgttg tgatatcatg tactgccact tcctcagcat
     3721 ggctaggacc agataataca acaattgcct gtcttttttc ttctggaatt tcttcagcca
     3781 aaacttctga gattcgttta tgcgtatctt gttctagtcc tttacttgca tgtataatga
     3841 ttggcttagt attcatttta ccaataagtt cctgtgcgac tgaacgaatc gcttttgttg
     3901 gaacaacaaa taaaatagca tctgcgttat ccactgcttc tgccaattct ttatatccga
     3961 taatcgattc tgggatcgtc aaatcaggta aaaaatgctg atttgtatga tacttattga
     4021 tttcatcaat ctgttcaggt acatttcccc aaatacggac atcatgcccg ttttctgcca
     4081 atgtttgtgc taaagcagtg ccccaagatc caggaccaag aactgcgatt ttttgtttca
     4141 tggatattcc tccaaataaa taattgataa tttccattat agtatacatt tcttaaagtt
     4201 gggactaatt tccattgttt ttaagtgttt gtttacttct tttatcgttt ttacttgaaa
     4261 taatcaatga tatgttacaa tagtctacat tttattttta cactcgttat gctttgcttg
     4321 ttcctaagag gaagcagttt tgacaatgtt actaccagca ttactattag gaggttagga
     4381 aacttctcct agtgagtatt gatttaaaat acataagaga cagattgaac atttctaaat
     4441 ctgtcaggtc ctgcaacgga cagattgtct ctgttgacgg ttgacatagg aacttttgtt
     4501 ttagtcaaca ttctggatac aaaacgctat gtaaactggc gcaactcgtt gtacttggac
     4561 ttttactacg gatccatgca acaactaaat agtactattg cataacaaaa aatggttggc
     4621 acccacatgt cccattaaac agattataag ttgaactgta gataatgcaa aaaatgtgtt
     4681 ttataacgta attgatgcca atattttaaa aaaataaagg gagcagttat cgctgctctc
     4741 tttatttttt atattctttt tatccagtct atcctaataa tcaaactgac gatagtagcg
     4801 gcgtatctct aatggatggc agttcaactg ctccacatga gcatcgatgc gttgtgtcac
     4861 tacatgcatc aataagaaag acaaaacacg tccgcgatat ttttcactga taccttctac
     4921 tggatagtct tttgtgtcta tcaatgtata attgctgcaa atttttggca aaagtttagc
     4981 cacacgttca gataacactc tctgttcatc ttcgcctaaa aataatgtga ctggggttgt
     5041 ttcttctacg atctctaacg tcccgtgaag aaactcggca gcatggatag atttcgatgg
     5101 aagccagctt tgttcttccc agtaacacat ggcatatgaa taaacagctc cccattgatt
     5161 ccctgctcca ataaaataat gcatactatc acgtcgatgt ttttctgcaa atgataagcc
     5221 aaatgcatct gcttttttct ctgcttccac taaccctgtt ggtaaataac gttcgagctg
     5281 ttcatagtat tctgaataag cttcgaattc tccattcaaa tacatcaatc gatctgctgc
     5341 cataaaaaat ttgatttgtt ctgttccagg agctggataa gtgaccacaa aatcgcatag
     5401 ctgagacaac ttactgttcg ctttatcgat aaatccaatc agtgtcgctc ctactttctt
     5461 gatttgttct actgctttca ctacttcttg agttgtaccg gtaacagagg acaaaataac
     5521 gatagaatct tttgttaatc ttttgtttcc agtagtgtaa tattctgcag catgctgtac
     5581 aaagacaggc aagttgcttt tcccattcat ataagtgaca gcttgcatcg aggaagcata
     5641 cgttccaccg attcctagat aatagacagc gtcaaatttt tccgcataaa gtttatcgat
     5701 gatttcttct acttgcggac gtaaagctag tgcgcctttt attgctttga tttgttcttc
     5761 ttcattgaat ttcagcatga tttccacctc ttataattta cttttcaaga ctgtatcaaa
     5821 gtcttcaaaa atctttttgt tcaagtcaat acctttagct actgcggttt tataagcgaa
     5881 tagttgaaac ggaacgacaa gcgctaatac agacagatat tcatcacatt ctattgctaa
     5941 tccaagtgtt ttctcgtttc ttgctttttt tgtggtaatg gtgagagtct ctccaacgta
     6001 ccgactcata tatctttgca acttttgcga acgttcctta tttacacttt ccccttcaat
     6061 aaagaatagc aaatgcgaag catctgcctc caggtatggg ccgtgcatat aagcttctaa
     6121 ctcaaatcct tgtgacggaa cgcggattgt ttcagtcaat ttcgtctctg cttctttagc
     6181 tgttccccag tttggaccat atccaatggt gacgaaacgc tgtgctaaac gaaataaact
     6241 ttgatatcca tcaaaaaatt cttccgtttt ttgaataatc gctggtaaat ggttgattat
     6301 tttgcgcaac tgttgcatgt agtcttgttc tatttttttg ctgattttat ttttacttat
     6361 tccaattcct atccctaaga gtagtaactg taaaacagtc gcagaatagc cttttgtaac
     6421 gaagcctact gattctaccc cggcacctaa atcaataatt tgtgcagctt ctaaagcaag
     6481 tggactttgc acgtcatttg tgatagcaac aacaggtaac ccttgttttt gtatcatttt
     6541 tactgcttca acagtagaag cacttttccc gctttgtgac acagcaatca cagtatcgat
     6601 tgaaggagaa agttttccat aattgaaaaa ataaaaaggt tcttgaatat cgacagtaag
     6661 atcaccataa gattccaatg ctggcttcgc tgctaaacaa gcgttataag atgaacccgt
     6721 tgctaagatc agtaaattca ctgttttttt catatgttct cttgtcgaaa aatcattctt
     6781 tttcaagatc gtacttagta cttccttttc ttcatagata taatcttgca tcgtaaacat
     6841 tttctctgct ccttttttaa aaaatcccta tccacgaacc aaaaattcca aagaaagcta
     6901 gtccgatcaa gatcgttaat ggtttcactt ctttcttcaa tagataaaac actatgccaa
     6961 atgctccaag acataagata tttggaacga tatcatcaaa aatactttga acagtcacag
     7021 cattttctcc tgaaccgatt tttaaaggaa tattgatggt gatcatcgtg gcagtcattg
     7081 ctccaacgac catcagtcca ataatagacg cgcctaatgt caaactttcc atcataccgt
     7141 ttgcctggat ctttttcaaa aaacccgttc ctaagcgata tccccaacct gttgctagat
     7201 agcgaaacag aatgtgcgga atattgaaaa tcaaaatgaa caagataggg cctaaaatat
     7261 ttccttgcat ggctaaagag gtacccacac ctgtggcaat caatcgcaaa gttccccaaa
     7321 agaaagaatc tcctaaccct gcaagaggtc ccatcaaaga tgttttgata ctatcgatcg
     7381 cagtcacatc aaattcagga tcatccttat tttcttcctc cattgcagcc gtgattccta
     7441 aaatcagtgt aacgatatgt ggggtcgtgt taaaaaactc tagatgccgt ttcaaagctg
     7501 ctgccatttc ttctttcgac tgatataact ttttcaaaat cggaatcatt gcataaacat
     7561 aagccatatt catctgacgt tcataattcc aagaaaactc catttgaaaa gaacgccaaa
     7621 atacgtgatt tagctctttt ttcgttattt tgctgttttt gatctcagaa ttcttcatct
     7681 tcttctacct cccctgcagt tgtttgaagt ggtagttgac ggacattcat aatattgact
     7741 accacaactg ctaaaatcgc accaaaaata gctactccgg tcacaggaat ctctaagtaa
     7801 gaagctatag caaaacctaa gaaaaaatat ggtgcaactt gtttgttgat cagcaaacga
     7861 gcaagcatcg caaaaccaag agctggaatc aaccctgtag ctactgacaa ccccttttga
     7921 acgaagtcag gaatcatatt taatagattt ccgatcgtat tgcttcccac catataagaa
     7981 accattacca caacaccaag catcaaggaa agaccgatac cggcaagcaa gtgcatatgc
     8041 tcgactcctt tataatttcc ttcttctgca taattgtctg ctttatggtt cataattgga
     8101 atcaaaagcc ctaagtaaat atttttcaat atcaatgtca acgtagcaat cggcaaacct
     8161 agtaaaagcg cggtttctgt accggctcca gctgtaatag caaaagccgt ccctaaaatc
     8221 ccaccggtca caacatcagg tggaatcgaa gcacctactg agaacgatcc gataaatgct
     8281 aactctaaag ttgcgcccat aatgatccca gtttttacat cacctaacac gattcctgta
     8341 aacagccccg tcacaatcgg acgagaaagc aacgatgtcc ctagtgcata ttctgattgt
     8401 gcgacaaatg caacaattcc taataagact gcttgtacaa tcattgaggt tcttcctttc
     8461 ttacaaaact tctcttacat ccactttttt atctgctggt acttgacgga tttctacttc
     8521 tatttgtttg tcaattaatc gtttcaagcg ttcctcctct tctggtaaaa tatttaccgc
     8581 ttttccgatg ctgcgagtac caggttttgc cttgatccct cctaagttga tggttttgat
     8641 ttctggatac gcttctgcca gcttatatgc atcctcgatc gattccacta cgatgaataa
     8701 cttatattta tctgtcaccc cgcttttcaa cgcggcaatc gagtcatcaa ttgatttgat
     8761 cactagtttg actccttgtg gcttggctaa tttgatcgtt gtctttcgta tctcattcgt
     8821 aggtacatca tcattagcaa tcaaaataca gtctgcgcct attgtttgtg tccatgaaaa
     8881 agctacttgt ccgtgtaata accgatggtc gactcttgtc aatacaatca tttttcttcc
     8941 tcctaaaatt cgtcttcttc tattttctga ttgagccgct cgttacaaaa ctggatcatt
     9001 ttttttgaat cagttagcac ctgctggatc aaaacagttg tctctacttc agcgtccaac
     9061 cgagatacta gctcaatcaa tagtggcaaa ttcaatccgg caacgagata gacatgatcc
     9121 cgattgatat attgtaagaa ttcgttgttg acacttccgc caaaaagatc cgtcagaaca
     9181 atgatttctt tatctttgta cctcataaaa agctgcctta ctgtttccgc taaatcaaaa
     9241 ttctcatcag tatagcaatc gaatacagta atagaatgat ttttcccata gatcagctct
     9301 aatgaatcta atatccctga agcaaatttt ccatgggaag ctaagataat ttctctatcc
     9361 actttttcat ctcctctttt cacttacaca tactaaaaaa gcaagttgca tgccaaaatt
     9421 agtggcaaca acttgcttat gttcaaaatt cttcttctat cgagagaaac tctgtatctt
     9481 cactcaaaat atcatagata taggcaatct cagaattggg gatcatgaca ctataatgct
     9541 cttcaatgac actaaacgca gatttaatag cagataaccc ttctttttga cactgcttcc
     9601 atttctctaa tccttgatag gtttcgattg gcatttgtcg gatcaatcgt tcaatgagac
     9661 agctcacatg gacatacaac gctaattttt tgggattgct gatgcttcga ttcaactgca
     9721 cctctaattc tctcataaaa tgatcgattt ctcccatcac cttctctgta tctagaatag
     9781 tcacggaatc cagtactttt tccaatgaaa aattacgaat gatgcgctga ttgaatattt
     9841 ccttctctga agcattcata gtagtgtcca accattcagc tagtacagac atcttttccc
     9901 ccgagatgag gtcttctaat gaaagatagt cgatattggt gatatcagga tctgtggtgc
     9961 caatcattcc tacgacttcg tatatggaaa ataatgggtc actgtttttc ttatctttta
    10021 attgctgata ttcatatggg atgattttca actgacaagc cgtaggtaag cttttttcta
    10081 gcagttcact taagtggacc gccgtaccga ttccagtgaa gcaagtagta atgagtgctt
    10141 tgggtttgtt ttcctctgga tagagcagtc gccattctgg ctggatctgt cgaacagtct
    10201 cttctgctat ctcttctaat gatacatttt tttgcaggca ttcccctact gtgattgcta
    10261 aaggtgtcgt cacattattc aaaatcaaaa gcggtacgga taactgtttt ttaaaaaact
    10321 gatggatttc tttcagagat cccatgtcta ctaatatgat caatccattt gaaacatcgc
    10381 tgttttcgca ataatcaagg atttctgaag caatctgctg tggtgtgaca tctagtggca
    10441 tatcaaatga ttcaaataga tcctcttgta ataaacgatt tactacattt gccatactgc
    10501 tagcagttgc ataaccgtga gcagcaatca tcgcttttgg cagtcgtttt tcttttgacc
    10561 atttcgcttt ttttagatag atcgtcagta aaatccgatc catacttgtg tcttcaatat
    10621 ctaatttgat cttacttaat tccagaattc gttggacata gtgataacta gatggataag
    10681 actgagaaac ttgttgttct aattctttga ttagttggat aatatcatgt tcttccggta
    10741 accatttgat agtgcttcgc tgatagagat agtaactcaa ggcatagaca ctgtttccat
    10801 cgaatttgat ttgataggca gtttccattt gtcgaaaggt ctctcggata gattgtgtcc
    10861 aataaaccag cagctcgtgt ttttcttgtc tactggtctc aaacagcaaa aaatcaaata
    10921 attgaatcac ttcttgcttt aattttcctt cgcaagaata tagcagacag ttatttttct
    10981 tgaaatcaat taggatttgc tcaaaacttt taacgattcg ctgctgttcg ggctgttgct
    11041 tctccattaa ttgctctaag gtctggtctt gcgtaatata gattccttgc tgtgctgtat
    11101 ttttagtaat aggctgcgca agtagttctt tttgcaaatg atggatcgtg acatggattt
    11161 caggctgttc acgctgttca gcatatgctt ttgctgctga aactttgacg atatttttca
    11221 gctctcctat gtttccggat aatttctgac ttgttaaaag tgacaaagct ggtccactga
    11281 ctgacaaagg gctccccatt tttctttgtt cttcgagaaa aaaagagtaa atcagttcta
    11341 gccgttcatt acgactacgc tgattaagtg caggtagttc gattcggata ggtattcttc
    11401 gaatgaaagt tgttaagaaa tgactagtaa tctcttcagt cgtagcaaaa aagagacgtg
    11461 ttttgatccg gcgtgacaaa ttaggttctc ccatacgata aatcacacct tgatcaagat
    11521 aggtgaacag tttttcctga ccttctggtg ttaagcgatg tacctcgtct aaaaacaaga
    11581 tcccaccatc tgctgcttca aaagcccctt ttttattttc ttctgcacca gtgtacgctc
    11641 ccttaacatg tccaaacaaa ttgctagtca aaagttcagg attatctgca tattgtgcac
    11701 aattaaaagt gatgaatggt gcagaatctt ctagcagatc atgaagcaga caatactgat
    11761 agaccaaatt aactaaataa cttttacctg tgccactttc gcctgtaatc aaaagtggta
    11821 atccgccatc tggatagtaa agagctgttt tgatttgttc gatactttct ttcaaactgg
    11881 cgtcgtatcc gatcataaaa gagaataagt cttttggttg cgcgaaaaaa ggctgttcct
    11941 ctttgagatc atcgatagaa aaataaaaat tcgtgcgtaa cttaaaaaat tgtttttcaa
    12001 aagcttcttt gtggaaataa atcactggtc gagaattgat tttgactagt agttgctcat
    12061 catttaactg gttcaaataa tgactgactg tgtttctttt taccccaaaa tgatcagcta
    12121 acctttgtgc tgtaaagacc tcgttcatat gttctaaatc gaaaaaggct gtctggttct
    12181 ctaagtaaca taaaatttcc ttcttcaaca acttattcac ccctcctcca tcatagaaaa
    12241 cggattcatt ttgtcaataa aatctttaat aaagaattga aaaatatatc ttattataga
    12301 cagcagccta cttatccctt ataattttta ttctaaaaaa cgtacagttc cttccagttt
    12361 ttatactgga atttcaacat atgaaagaat aaggaggcta tgactattca atgaaatcgg
    12421 ataaatataa aaacaggaaa catacttcct ggaaaacttt tcgagaaatc atcggatctt
    12481 atctcgctgt agttgtattt ttgcctttgc tttatatggc tatgacagaa caaactcgtt
    12541 ttattggcgt agatacgcaa tatatagccg aaacaggatt tttattcatc tttatcttga
    12601 tttttgcgtt ctataaatcc ttccatacaa aataagattc acagatttca actttcctgt
    12661 ctgtttttag ctattacaaa tccttatatg tggtataaca acaatttatt ggcataatga
    12721 ggaaaaacga gttatgatgc tttcagagag taaagaggta ctgttgtcac catccttttt
    12781 attgattacg tacaccactc ttagtttttt cccattgatt acgaaaacaa ggtagaaaca
    12841 ttgatgttcc taccttgttt tcttttttta ttttcagatc aaaatctcaa gtagcttttg
    12901 acttgatgtc gggaggttgt cttcgttcca tcaaacctga tagaatctgc gccaaaccat
    12961 agttttctcc actattattt attcctctaa gatagtaccc acaataaacg aataaatatt
    13021 tttctcattt tcatactcct tctttgaaaa tcaattagat ttctctcaac ccactttttt
    13081 acaaaaatta cgtagcaaaa aagattgcaa gaacaaatta aaaaagaagt aa
//
LOCUS       DADVXB010000078        12938 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.079, whole genome shotgun sequence.
ACCESSION   DADVXB010000078 DADVXB010000000
VERSION     DADVXB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.079"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="KB902_001750"
     CDS             complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="KB902_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6808576.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1197..3038)
                     /locus_tag="KB902_001751"
     CDS             complement(1197..3038)
                     /locus_tag="KB902_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6808577.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3220..5535)
                     /locus_tag="KB902_001752"
     CDS             complement(3220..5535)
                     /locus_tag="KB902_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6808578.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5720..6580)
                     /locus_tag="KB902_001753"
     CDS             complement(5720..6580)
                     /locus_tag="KB902_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6808579.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6639..7269)
                     /locus_tag="KB902_001754"
                     /pseudo
     CDS             complement(6639..7269)
                     /locus_tag="KB902_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            7436..8197
                     /locus_tag="KB902_001755"
     CDS             7436..8197
                     /locus_tag="KB902_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6808580.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            8223..10814
                     /gene="mprF"
                     /locus_tag="KB902_001756"
     CDS             8223..10814
                     /gene="mprF"
                     /locus_tag="KB902_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6808581.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11002..12189)
                     /gene="tuf"
                     /locus_tag="KB902_001757"
     CDS             complement(11002..12189)
                     /gene="tuf"
                     /locus_tag="KB902_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6808582.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12557..12913
                     /locus_tag="KB902_001758"
     CDS             12557..12913
                     /locus_tag="KB902_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6808583.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         3709 a         2709 c         2298 g         4222 t
ORIGIN      
        1 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
       61 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
      121 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt tccctacttc
      181 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
      241 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
      301 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
      361 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
      421 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
      481 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
      541 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
      601 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
      661 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
      721 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
      781 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
      841 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
      901 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
      961 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
     1021 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
     1081 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
     1141 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
     1201 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
     1261 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
     1321 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
     1381 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
     1441 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
     1501 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
     1561 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
     1621 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
     1681 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
     1741 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
     1801 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
     1861 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
     1921 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
     1981 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
     2041 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
     2101 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
     2161 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
     2221 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
     2281 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
     2341 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
     2401 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
     2461 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
     2521 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
     2581 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
     2641 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
     2701 gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
     2761 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
     2821 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
     2881 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
     2941 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
     3001 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
     3061 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
     3121 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
     3181 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
     3241 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
     3301 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
     3361 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
     3421 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
     3481 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
     3541 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
     3601 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
     3661 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
     3721 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
     3781 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
     3841 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
     3901 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
     3961 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
     4021 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
     4081 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
     4141 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
     4201 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
     4261 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
     4321 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
     4381 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
     4441 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
     4501 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
     4561 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
     4621 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
     4681 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
     4741 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
     4801 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
     4861 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
     4921 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
     4981 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
     5041 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
     5101 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
     5161 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
     5221 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
     5281 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
     5341 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
     5401 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
     5461 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
     5521 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
     5581 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
     5641 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
     5701 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
     5761 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
     5821 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
     5881 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
     5941 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
     6001 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
     6061 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
     6121 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
     6181 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
     6241 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
     6301 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
     6361 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
     6421 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
     6481 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
     6541 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgca ctccttcttt
     6601 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
     6661 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
     6721 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
     6781 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
     6841 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatac
     6901 ttggacagct gtccataaat cgcatccttg tttctttgct tctactatca tttccgccaa
     6961 atatttgaca ccttgatcaa tactgtcagc tggattatca atgatctcag cttctccatg
     7021 cagactttcc gagctctgca tgagatctgt cccttttcct tttgattcgg tcaatattat
     7081 cgccttgatc aaattctcgt agttttccat atgataattt tttgcagctg ttgttatttc
     7141 tatttgatag ctttccactc gttttaccga acgataagtt cttcctccta aaaacaacac
     7201 cgcaccaata accgtcagaa tgatcatgta aaaaagaata cggataatag ataatcgttt
     7261 tcgcttcatt tcatcaccta gttattttga catctttttt tatcttacta tttctttatc
     7321 ttcttggcta tttcttcctt gatttctgtg tacgccttaa gaaaaaatga attttcctgt
     7381 attttttgac atcttacgaa aatgatcgtt gtttttcagt aaaaacaatt gcccaatgac
     7441 tgatataatc gttatacttt acacagtagg tgattatgtg aaaaaagaaa agaaatatgc
     7501 aaaaatgcca gatgggagcg aaatttacta tgaaaagagc ggtcaaggct tccctctctt
     7561 tttactgcat ggcaatgacg gcagcggccg ctttttttca gaacaggtcc ctgtactcga
     7621 acgctactat accgtgtatc tagtagatag ccgaggacat ggtcgttcga caaacgaagc
     7681 atctatgttg aattttcagt taatggccga ggatctgaat acgatcatgt tgctggaaaa
     7741 aatcgatcag gcagattttc ttggatttag tgatggagca aatctagcac tggtatttgc
     7801 cagcagcttc cctaaaaaag ttcatcgatt gattttaaat tctggaaaca cgcttgttaa
     7861 aggcgttcgt ttttctgcca gagtcatcag taatattcat tatgcatggg tatggttact
     7921 ctctttattt cgcccaagtc ttcgcaaaaa tcttttagtt atcaaacttt tgctgcatga
     7981 catcgggctt acagaaaatg atttaaaaaa aatcaactcc cccactttga tcatcgtggg
     8041 aaaaaaagat gtaatcaagc taaaacattc tttgtatata gctaaaacta taccaaaagc
     8101 ttcctttgtg cttgtgaaag aacaaggaca tgaattagct agaaaagatc ctgaacgctt
     8161 caatcgagaa gttcttcaat ttctttctga aacataacta ttaggaatag aaggtgattt
     8221 atttgttaaa aaataccata caatggctga aaaaccacct aggactgttc aaaacaatct
     8281 ttttgatttc tgtcattgtc attattgtcg gtgaattgat gtccatcggt aaaactctat
     8341 ctatccagca attaggagaa acgtttgcca ctatacctgt atggaaaagc ggactaatgc
     8401 tattgattgg tcttatctct gtgttaccta tggttggtta tgatattatt ttgaatcgga
     8461 tgcttgaaca aaagcagaat cctcgttacc tgtttgagac aagctggctg atcaatacga
     8521 tcaacaatat tgccggtttc ggcgggtttg ttagtgtggg gcttcgctct gaactatatg
     8581 gacaaaagaa agagagcaga aacgtgatcc aagcattatc gaaagttttc ttgtttttga
     8641 tggctggact ttctatttac agtctgcttt cttttttact tgtagtcttc acgccagttg
     8701 ctcctttttt gaagcaatat tggatatggt tgatcggcgg cggtctatat tttcctgtcg
     8761 tctttttatt tactactttc aaaaagaaag gattccttgg tggtacctca cttaaaactc
     8821 aaggacagct attgctagtt tcattgttgg aatggaccgg tgtcctgttt agtttccttt
     8881 ctgttggtta tttaatggaa atccggattg atctgtggca aacaattcca ttattcattg
     8941 ctgcttcagt gataggaatc gtgtctatga ttccaggaga aattgggagt ttcgatgtaa
     9001 tgatgattat cgggttgtcc gctattggtg tgccaagaga aatagtcgtt gtgtggatct
     9061 tgctctatcg cctgttctac tacatcattc cgtttttgat tggaatcgtc tttttcttca
     9121 aaaatatcgg ttccactttt gatcagcgtt attctggtat ccctaaacaa ttagcaacag
     9181 aaattgcgca taaaatcgtg gttgtcttat tatacttttc tggaatcatg ctagtacttt
     9241 ctgccactat cccgcaagct tttacagagt ttcgctggct tcatagtttg aacccattga
     9301 aatttcattt tattatccaa tttcctagta tactattggg atttctttta atcattatgg
     9361 gcagagggat cgcagcacgt gtgaaacgag catatttgcc tacaatcttc ttgattgttc
     9421 tagctttact ttatgtttta ttaagtgatt ttagtttcac accggtggtt ttcttgtcta
     9481 ttctgcttct gatcattctt gcttctaaaa acgaattatt tcgggaacaa ttgatctatt
     9541 catgggagtg gcgtacgatc gatggaatca ttattggtgc actgtccttg ctttacatcg
     9601 ttattggggt atacaatctg ccagatttcc ctcatcggcg tcaccatttt atttcctttt
     9661 tcttatttcc ttctgaaaag atttggtttt cgggattgtt ggccatcatc gctgttagtt
     9721 tcatgatcgt tctatttgtt catttccttc aaggagaaaa gaaacagatt ggcgaagcct
     9781 ttaatgaaga aaaggccctg aagatcctta caacttatgg aggaaactcc gatagtcaat
     9841 tgatcttctt aaaagataag cggatgtttg cctatgaaaa agacggtgaa ccaactgttc
     9901 ttctccaatt cgcttgcttc aataataaat gtattgtaat gggtgatcct tctggtaaga
     9961 aagaagattt tccagaagca atcgaagctt ttatcgaaga aacagatcga ctatgctatt
    10021 taccagtttt ctacgaaaca agcgaagaga ttgttatgat tttgcatgaa ttcggctacg
    10081 atttcattaa gatgggggaa gaagcttatg tagacctgaa tagttttaca acttcaggga
    10141 aaaaaatgaa gggcactcgt gctgtcttga atcggatcga acgagaagga tttacatttg
    10201 atgtcttaca accaccattt tctactgagc aaatgagtac tttcaaaaat atctctgata
    10261 attggttggg ttcacgaaag gaaaaagggt tttctttagg ctttttctct gaagattatc
    10321 tacaaagagc gcctattgca gttgtcaaaa atacccaaga agaaattgtc gcttttgcaa
    10381 cgatcatgcc tacttacacg aacaataaag taggaacgat tgatctgatg cgatatgatt
    10441 ctaaaaaagc accttctggc agtatggatt tcttgttctt gcatttgttt gcctatatga
    10501 aagaagaaca tatccaatgg ttcaatttag ggatggcccc tctttcaaat gtcggaactt
    10561 ccagaaagag ttttttacag gaaaggattg catacttggt ttacgagttt ggttctcatt
    10621 tttattcttt ccatggatta agagaatata aaagcaagta cgctacaaac tgggtctcac
    10681 gttatactct atattctaga gatagttgga ttgcatatgt tatgattgct ttgctgatta
    10741 ttgataatgc gccagttgag cagacacaag gtagaataag tggtttgaaa aaatggatac
    10801 gaagaaagta ttaaaaactg cataccgata gatgaacact ctcatgatga ataaaagaga
    10861 ctgaagtaaa acgaaagttc atgcttctac aatctcttct tatacaattg aagaacaaag
    10921 agcggtccaa acagaaatcc tgtttggacc gctcttttat tttaaacatt tttcattacc
    10981 aaaatattcg agtcgcgttt cttatgcttc gatctctgta acgatacctg aacctactgt
    11041 ccgtccgcct tcacgaattg agaatgtcgt tccgttttca acagcgattg gatggatcaa
    11101 gtcaacatca atcgtcacgt tgtcaccagg catgaccatt tctgtatctt ctggcaatgt
    11161 gattgttcct gtaacatcag ttgtgcggaa gtagaactgt ggacgatagt tgttgaagaa
    11221 tggagtatga cgtccacctt cttcttttgt caacacgtac acttctgctt tgaattttgt
    11281 atgtggagta atggaacctg gtttagcaag tacttgtcca cgttcgatat cgtcacgttg
    11341 gatcccccgt aacaacacgc ctacgttatc cccagcttcc ccgtaatcta acgttttacg
    11401 gaacatttct acacctgtta caactgcttt ttgtgtttca ggtttgatcc ctacgatctc
    11461 tacctcatca ccgacacgaa cagcaccacg atcaatacga cctgaggcaa cagttcctcg
    11521 acctgtaatt gagaagacgt cttccactgg caatagtaat ggtttatctg tatcacgttc
    11581 tggtgttggg atatattcat ctactgtatc catcaattcc ataatagcag cttcagcatc
    11641 tggatcgcct tgcaatgctt ttaatgcgga acctttgatc acaggagtgt catcgcctgg
    11701 gaaaccatat tcgctcaata actcgcgaac ttccatttct accaaatcga tcaattcttc
    11761 atcatcgact aaatcaactt tgttcaagaa aacaatcagg tattttacac caacttggcg
    11821 tgacaataaa atgtgttcac gtgtttgagg catcggaccg tcagttgcag aaacaactaa
    11881 gattgcacca tccatttgtg ctgcccctgt aatcatgttt ttcacatagt ccgcgtgtcc
    11941 tggtgcatca atatgcgcgt agtggcgttt ttctgtttca tattctacgt gtgcggtatt
    12001 gatcgtaatc ccacgttcac gttcttctgg agctgcatca atactagcat agtcttgagg
    12061 atttgctagg ccttttttgc ctaatactgt agtgatcgca gcagttaaag tagttttccc
    12121 atggtcaacg tgtccaatcg taccaatgtt aacgtgtggt ttacttctgt cataatgttc
    12181 ttttgccata atttacaaac ctcctaaata atatagatca ctgaaaaatt tcagctctca
    12241 cctttttatt atagtctttt tttgactaaa tcaaaaagaa tacgtccgac ttactttttg
    12301 taagattcga actaagctta ttatacgtca atattggtca aagtcaacta agagcactcg
    12361 tctgtcttat acgcgaaaaa agtacctttt ataaataaaa aaatgtgttt tttgagaaaa
    12421 acttcaagat agtccttaac tttcttttga agcaataaga acaaaatgag gaaaagttta
    12481 aaattcagct gttgccaaca actttcaata gacgaaatct tctatttcgt taataataag
    12541 gaaagaggtg aagtacatga aaaaattaat tggcgtactt gtcgttttag gcatatttct
    12601 cggcggaagt tttgcagctt atcattattt ttacggcggc gaagcttatt atacaaaaat
    12661 cacgacgaat ggcgaaatgt cagctaccca agcagataac ggagagaaat tcacgactta
    12721 tacctacaag caagcggctt ataataaaga tggtgaaaaa aaacaggtga cgcttcgcga
    12781 agaaagagaa catccattaa agatgaatgc gtatcttaaa ctcaaagtca atcctcgtaa
    12841 aggtgtatta agctgggaag aaataaaggc ttctgaagtg cctaaaaatg cggcagaaaa
    12901 aatcgataat tagtaaatgg tcttaaaatt ttattaga
//
LOCUS       DADVXB010000079        12265 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.081, whole genome shotgun sequence.
ACCESSION   DADVXB010000079 DADVXB010000000
VERSION     DADVXB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.081"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(46..390)
                     /locus_tag="KB902_001759"
     CDS             complement(46..390)
                     /locus_tag="KB902_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808584.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(466..1713)
                     /locus_tag="KB902_001760"
     CDS             complement(466..1713)
                     /locus_tag="KB902_001760"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBB6808585.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            complement(1710..2516)
                     /gene="proB"
                     /locus_tag="KB902_001761"
     CDS             complement(1710..2516)
                     /gene="proB"
                     /locus_tag="KB902_001761"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBB6808586.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            2746..3273
                     /locus_tag="KB902_001762"
     CDS             2746..3273
                     /locus_tag="KB902_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBB6808587.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            3336..4706
                     /gene="radA"
                     /locus_tag="KB902_001763"
     CDS             3336..4706
                     /gene="radA"
                     /locus_tag="KB902_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBB6808588.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            4740..5897
                     /locus_tag="KB902_001764"
     CDS             4740..5897
                     /locus_tag="KB902_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBB6808589.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            6067..7527
                     /locus_tag="KB902_001765"
     CDS             6067..7527
                     /locus_tag="KB902_001765"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBB6808590.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     misc_binding    7524..7763
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7849..8385
                     /gene="cysE"
                     /locus_tag="KB902_001766"
     CDS             7849..8385
                     /gene="cysE"
                     /locus_tag="KB902_001766"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBB6808591.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            8382..9794
                     /locus_tag="KB902_001767"
     CDS             8382..9794
                     /locus_tag="KB902_001767"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBB6808592.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            9791..10186
                     /locus_tag="KB902_001768"
     CDS             9791..10186
                     /locus_tag="KB902_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBB6808593.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            10179..11039
                     /gene="rlmB"
                     /locus_tag="KB902_001769"
     CDS             10179..11039
                     /gene="rlmB"
                     /locus_tag="KB902_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBB6808594.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            11043..11573
                     /locus_tag="KB902_001770"
     CDS             11043..11573
                     /locus_tag="KB902_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBB6808595.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            11650..12228
                     /locus_tag="KB902_001771"
     CDS             11650..12228
                     /locus_tag="KB902_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6808596.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
BASE COUNT         4028 a         2296 c         2664 g         3277 t
ORIGIN      
        1 tttttgccga tcttcaaggc actctactta tcgtacggat attttttagc ggaaagtccg
       61 attcaagtgg tttttattca gctgatattt ataagataag tgaaaaatcc cagcaatcag
      121 tagcgtaatc gtataagcga ttgaatgatc gaaaaaagaa tagtaattga ttgtcgctaa
      181 taagcataat gcaaccatgt aactaatgtg caagcgtgta accagccctt tttgcccgat
      241 tttgtcaaaa tactgcgacc atttttcccg ttgactccct atgcttcgtt ttttgaattg
      301 aaagaaaagg gataaaatac cgactcccag aaaagcagcg atattcagag aaataaggta
      361 aataaaaaaa atcattaaaa tttcaaacat attgacacct ttctagttgg atagaacctt
      421 tacagaaaaa aggcaaaagg cgggaataat gtttcacacg aaacattatt cgcggatttg
      481 tccatcgcca taaatgatat attttgtgga agttaattca tttaacccca ttggaccacg
      541 ggcatgcaac ttttgagtag agataccaat ctctgcacca aaaccaaata ccgatccgtc
      601 tgtaaaacga gtggaggcat tgacatagac agccgccgcg tccacttcat ttaagaaacg
      661 ttgactagcc gcataactat ctgtcacgat cgtttctgaa tgtttagtat tatgccgatt
      721 gatatgtgca attgcttcat ccaaagaatc gaccactttg acagcaagga tataatctag
      781 atattcagta tcccaatctg tgtcttctgc taaagcagcc gtctctagat attctaacgc
      841 acgagcatcc gcacgtaaag agaccccgtg ttctaccagt tctttttcaa tagctggcaa
      901 gaaaaaaggt gcgatctcag aatggatcag caatgtttct gccgcgttac agacagatgg
      961 acgggaagct tttgcattga cgatgatgtt cactgccata gataactgtg cttctttatc
     1021 gatatatacg tgattatttc ctgtacctgt ttcaatgata ggtaccgttg cctgttcttt
     1081 gactcgttgg attaattttg ctccgcctcg aggaatcagc acatctaagt attctgtcaa
     1141 tcgcatcaac tgtcctgcag tttcatgaga agtatcatcg acaaactgga tggcataagg
     1201 agattcgcca gcactgacca gtacttgctg caataattgg actaataatt gattcgagaa
     1261 gaatgcttct ttgccaccgc gaaggataac ggcattccct gatttgaatg ctagactagc
     1321 tgcatctgtc gtgacatttg gacgagattc gtaaatgatg ccggtcacgc ctagtggcac
     1381 gcgctttttg ccgattctca atccgtcggt gttcgtccac atctcatcta cttttccaat
     1441 aggatcgtct aacgaagcaa ttttttcgat ctctgtagcc atggcattga ttcgctcagg
     1501 tgtcagctgc aagcggtctt gcatcgtttc actgatattg ttttcgactg ctttttctaa
     1561 gtctttatga tttgcttcaa tgatcgcttg ttgattcttt ttgatggttt gtgccatttg
     1621 aacaagtagc tcatttttgc ggtttgtagg cataagtgct agttgttgcg cgctatcttt
     1681 tgcctgttgt cctaattgca tcaagtcagt catttcaagt cctccttaaa taaagtacct
     1741 acttcttttc ctgcaagaat atcaaaaata attgccggat tttttccatt tgctaaaatc
     1801 attgcgctgt ttgcttcaaa tatcctagaa gcggctttta atttactctg cataccgcct
     1861 gttccaaatg tgctaccagc accacctgct tgtgccagaa tcttttcatc gattttatcg
     1921 atatagcgat acatctgagc ctcgggattt gtagtcggat tatctgaata aaacccgtcg
     1981 atatcagaaa ggacgatcaa aaggtctgcc gcgacaagtt ttgccatgat ggctgacagc
     2041 tgatcattat cgccaaattt tgtcagatga tctaattcat ccactgctac agtatcgttt
     2101 tcgttcacga tagggatcgt gtccataatc aaaagctgtt ccaatgtatt cctcacattt
     2161 ttacgacttt caggataatc taccacgtct cttgtcacga ggatctgtgc cgtctgttga
     2221 ttatatacac tgaatctttg attatagata ttcatcagtt cggcttgacc aacagccgcc
     2281 gcagcttgct gttcaggaat caaagtcgga cgttctgaca aatgtaattt atgcatacca
     2341 acgcctacag ctcctgatga gactaagatc acttcctttc cccgatttct aagatcagaa
     2401 aggacaaaag ctaactgatc gattgccgca agattgatat ttccattggg ataaatcaat
     2461 gtacttgttc ctactttgac aataattcgt tttgcatttt taatttcttt acgcatgtga
     2521 cacctcaatc aaatatccac tcattaattt cgttctattc tacttgtttt gacgagtaaa
     2581 gtcatgtaaa aaatagtttt tttgtacaac ttgcagtcgt ttggaaaaag aacgaattaa
     2641 tggtttactt taagatagca gaatttcttg aagaatttgt aaagaaagtc ttttacagcc
     2701 tcggatatgt tagaatagga gtagtttatt tagggaggaa aaccggtgag aaaaagagga
     2761 tttgaagtta tttctaaata taaagatcaa aatatcaatc taccgcagcg cgctacacat
     2821 catgctgctg gctatgattt tgaagcagca gaagaggtcg tgattccaag tatctggaaa
     2881 gcaggctgga aaaaggggtt ggaaacagtc gcagatggat tgaaaaaaga tgtatcagaa
     2941 aatgaaaaac aattgaaacc aaccctcgtg cctactggaa tcaaagctta catgggagaa
     3001 gatgaatttt tgcagcttgc taaccgttca agcaatccgt tgaagcggtt tttagtgttg
     3061 acaaacggag taggtgtgat tgacagtgat tattacaata atgaggcaaa tgaaggccat
     3121 atcatgttcc aattcaccaa ctttggtttc aaggatgtag tgatcaaaaa aggcgagcgt
     3181 atcggccaag ggatcttttt gccgttttta aaagcagatc aagatcaaac gactgctcaa
     3241 cgtcaaggcg gatttggttc ttccagtaaa taaaacgtta aagatactta agcttgattt
     3301 aatgtctcat gattaggata aaaggaggcg gtacaatggc aaaaaaatca aaagtacaat
     3361 ttgtttgcca aaattgcggg tatgtgtcgc ctaagttctt gggacgctgc ccaaattgcg
     3421 gaaaatggaa tacgatggtc gaagaaatcg aacaagatac aacggaccgc agaactcgga
     3481 caagtttgac aggagaaaaa gcaaaaccaa caaaaatcgc agacgtcgtc cctaaaaaag
     3541 aacctcggat caaaacaaaa ttagaagaac tgaaccgtgt gttaggcgga ggtgtggtgc
     3601 cagggtctat ggtcttgatt ggtggcgatc caggtatcgg gaaatccact ttgctgttac
     3661 aagtttctca gcaattagca gccataggcg gaaaagtctt atatgtatcc ggcgaagaaa
     3721 gcgcagagca gataaaatta cgcgcggaac gcctcggaag tatcaacaca gaattttatc
     3781 tatacgctga aacagatatg aacgaaatca gtcgtgccat cgaacatatc tcccctgatt
     3841 atgttatcat tgattccatc caaacgatga cgcagccaga catcacaagt gtggcaggaa
     3901 gtgtcagcca agtaagagaa accactgcag aactactcaa aatcgctaaa acaaatggga
     3961 tagccatttt tatcgtcggt catgttacca aagaaggctc gatcgccggc ccaagaatgt
     4021 tagaacatat ggtggatacg gtgttatatt ttgaaggtga acaacatcat agttttcgga
     4081 ttttgcgagc agtaaaaaac cgatttggct caacgaatga gattgggatt tttgaaatgc
     4141 atgagcatgg attggaagaa gtcgctaatc cttcacagat tttcttagaa gaacgcctag
     4201 acggtgcaac tggctctgct atcgttgtgg caatggaagg gacacgtcca attttggtag
     4261 agatccaagc attagtcaca cctactatgt tcggaaatgc caaacgaaca acaacaggtc
     4321 ttgatttcaa tcgggtatct ctgatcatgg cagtgctgga aaaaagagct gggttgcttc
     4381 ttcagaatca agatgcttac ttaaaagctg caggtggggt aaaattaaat gaaccagcga
     4441 ttgatttagc tatcgctgtc agtattgctt caagctataa agaaaaagga acacagccaa
     4501 cggaatgttt catcggtgaa attggactga ctggagaaat cagacgtgtc agtcatattg
     4561 aacaacgagt caaagaagtc caaaaactcg gcttcacaaa agtataccta cctaaaaaca
     4621 acttaggtaa ctgggaagcg ccaaaaggaa tcgagatagt tggagtagca actttggctg
     4681 aaacgttgaa gcgtgtgttc cgctaactaa taaatgattg tcgaaacgga ggaaaaacga
     4741 tgcaaaaacg tgtcattact ttgctgatga tcattgtcgg cgcaagcttg ggtatttcat
     4801 ttttaccctc agcttggcag gcaatcggtc aacagtcaaa cggatggctg aataatacat
     4861 ttaccaacag cctgttaggc gcacttattt tctttttatt atctttgctg ttggccaaac
     4921 atatctcagc tattatcaaa caagtagaac aaaaactaag tgaggtcagc ttgacttatc
     4981 ttctcttcgg tgcgatcggt gcgatcatcg gattgacttt aggtgttgtg atctcgaccc
     5041 ctctttacaa tatggaaatt ccattcgtca atagtgtatt gccgatttta ctgatgatca
     5101 tcttaggcta tctgggattg agaatgggaa cgacacgaat cgaagaatgg aagaaagttt
     5161 ttggttcacg aagcaaaaaa atcgagcaag aaacagctag tcaagttgag agtcaactgt
     5221 tagaacgaaa atcaggagaa aatttccata aatataaaat cttggataca agcgtgatca
     5281 ttgacggtcg gatttatgat attacaaaga ctggattctt agaaggaacc ttgatgatcc
     5341 ctaattttgt tctttacgaa ctacaataca tcgcggactc aggggatagt ttgaaacgtg
     5401 tgcgtggtcg tcgcggatta gatatcctaa atgccttgca aaaagaagag ggtatatctg
     5461 tcgaaatgta cgatggagac tttgaagata tcagtgaagt agacagcaaa ttgatcaaat
     5521 tggctaagct tttagatggt gtcattgtaa ccaatgacta taacttgaat aaagtctctg
     5581 aattccaaaa tgtacctgtt cttaatatca atgcgttggc aaatgccgta aaaccagtcg
     5641 tcatccctgg tgaaacgatg aatgttctag tagtaaaagc cgggacagaa cgccaacaag
     5701 gagtagccta ccttgatgac ggcacgatgg ttgtcgtaga agatggacag cattacatga
     5761 atgaacgtat cgaagtcgtt gtaacaagtg cccttcaaac agctgctgga cgcatgatct
     5821 ttgctaaacc tgcacatgca ggacgaggaa tcgacaataa aaaagagaca gagaaaaaga
     5881 ctaaacaatc aaaataaaaa agaaattcag ccaactggta aggaaattca accagttggc
     5941 tttactattt accttagaaa aggtaaaatt tgtgctgagt ggctttaaat aaatgatatt
     6001 tgagaagccg taactgacgg aatttttgct gttagtcaaa gtctagtttg aaagaagagg
     6061 aagaaaatga cgaaagtacg cgtacgctat gcaccaagtc caactgggca cctgcatatt
     6121 ggaaatgcaa gaactgcatt attcaattat ttgtttgccc gccacaatga tggagacttt
     6181 attattcgta ttgaggatac tgaccaaaaa cgtaatatcg aagatggcga aaaaagccag
     6241 ttggaaaacc ttgcttggtt gggaatgaat tgggatgaat ctcctgaaaa tcctggagaa
     6301 tacggccctt accgtcaatc tgaacgtaaa gaaatctatc aaccgctgat tgatcagctg
     6361 cttgctagca atcgagcata caaatgctat tgcacagaag aagaattaga agcagaacgg
     6421 gaagcacaac gcgcaagagg agaaatgcct cattacgcag gaacatgtgc gaacttgaca
     6481 cctgaagaac aagcagaaaa agaagcacaa ggtctagaat ctgttgtacg tttccgtgtg
     6541 cctcgcaata cagaatacgc atttacagat atggtgaaag gcgctatttc gttcgaatcc
     6601 gataatatcg gtggcgactt tgtcatacaa aaacgcgatg gtatgccaac ttataatttt
     6661 gctgttgcgg tcgatgatca tttgatgaaa atcactcacg ttttacgtgg agatgaccat
     6721 attgccaata caccaaaaca actgatgatc tatgaagcat ttggctggac accaccaacc
     6781 ttcggacata tgacattgat catcaacagt gaaacaggta aaaaactaag caaacgtgac
     6841 gaatcaatct tgcaatttat cgaacaatat cgcgaattag gctatctacc agatgcaatg
     6901 ttcaacttta ttgcattatt gggctggtca cctgtgggcg aagacgaaat cttcgaacac
     6961 caagaattga tcaaaatgtt cgatccaaaa cgcctaagta aatcacccgc agctttcgat
     7021 gcgaaaaaac tgcaatgggt aaacaaccat tacatcaaag caatggatct agatgcattt
     7081 actgacatgt gtctgcctta tctaatcgct gatggacgtg tagcagaaaa cccagatgaa
     7141 aagacaatcg aatgggtgaa gaagatcgtt agcctgtatc aacctcaaat gagctatgct
     7201 gcagaaatcg ttgatctgtc tacgctattt ttcaatgaac atcctgtatt gaatgaagca
     7261 gcaaaagaag tacttgctgg tgaaacagtt cctactgttc tccacgcatt caaagcacag
     7321 ctagaacaaa tggaagtagt agatgctcca actgtcaaag ctgccatcaa agctgttcaa
     7381 aaagaaactg gcgtaaaagg aaaaaatctt ttcatgccaa tccgtgtagc tgtatcagga
     7441 caaatgcatg gtccagaatt gcctgaaacg atcgaattgc ttggtcgtga aaaatcatta
     7501 gcacatttaa atcaagtact gaactaaaca cgatgaacag aaaaaagtaa gcagctgatc
     7561 attacaagag agataccggg tggtgcaagg tatcaatgaa tggttgccga aatgcctctg
     7621 ggagtggtct tggcgaaaca cagaaaacag gaaaaactgt tttataggaa acaaagtagc
     7681 caagaacgta taacaggcgt tagctgtcag agataatcat tgattatgaa gaaaagtgga
     7741 accacgcgga aagcgtcttt tgataaggaa acttatttaa aaggcgcttc ttttctttat
     7801 aagaagatga tttcctacat aaaattctta cgaaaggagt ggaaagtcat gagttggttt
     7861 acccgagcga ttgatgcagc aaagagaaac gatccggctg cacgttcgac agctgagatc
     7921 gttttgacat accctggttt tcatgccttg ttttggcatc gtttctctca ttttttatat
     7981 cagcaccggc tctttttatt ggcgaagatc aatgctcaat tctggcgttt cctaactggt
     8041 gttgagatcc atccaggagc aacgattgga actggcgtgt tcatcgacca tggaatggga
     8101 atcgtcattg gcgaaaccgc agaaatcgag gacgatgtga ttttattcca tggcgtaaca
     8161 ttaggcggca caggaaaaga aacgggtaaa agacacccaa ctgttaaaca aggagccatg
     8221 ctctctgcga atgcgcagat attaggaccg gtaacgatcg gaaaaaacgc caaaatcggt
     8281 gcaggtgccg ttgtgttgaa agatgttcca gacgacgcta cagcggtagg agtaccagca
     8341 aaagtcgttc gaatcaaagg agaaaaagtg aggagatcag aatgataaaa atctacaata
     8401 cattgaccag aaaaaaagaa gaattcatcc ctatacaaaa gggacatgtc ggtatgtatg
     8461 tctgcggacc gactgtgtat aattatatcc atatcggaaa tgctcgtagc accattgctt
     8521 tcgatacaat tcgacgctat tttgaatatc gaggctataa agtcgatttc gtatcgaatt
     8581 tcacggatgt agacgataaa atcatccgta cagcaaacga attaggtatt acagcaccag
     8641 aagttgctga tcgtttcatc cgagcatttg aagaagatac gaaagcgttg aatgtcgagc
     8701 ctgctacact gcatccaaga gtcatggatc atatgccaga tattttagca tttattcaag
     8761 tgttggttga aaaaggctat gcttatgaat cttcaggtga tgtgtattac cgtacccgta
     8821 aatttgaaaa ttatgggaaa ttaagtgacc aatccatcga tgaactggaa gtcggagcaa
     8881 gtcagcgtac aggggaagaa cagcagcaaa aagaagaccc attagatttc gctttatgga
     8941 aacaagcaaa acctggcgag atttcttggg attcaccatg gggcaaagga cgtcccggtt
     9001 ggcatattga atgttccgtt atggcaacaa aacatttagg agaaacgatc gatatccatg
     9061 gtggcgggca agatttagaa tttcctcatc atgaaaatga aatcgcacaa agtgaagcga
     9121 aaacagggaa aaaattcgct aattactgga tgcacaatgg ctatgtaacg attggcgaag
     9181 acgatgaaaa aatgagtaaa tctctaggga atttcatcac tgtacatgaa atgatcaaaa
     9241 acgttgatcc acaagtcttg cgtttcttca tggcgaccac acaataccgt cgtccgatcc
     9301 gctacagtga aacgacgatg aaagaagcag ccaccaattt acaacgactg aagaatacgt
     9361 ttgacaattt gaaattccgc caagaaactg cctcagagaa tttggcagat gatgcggata
     9421 aaatcgcttt gttagaaaat ttagaacagc gattcatcga agaaatggac gatgatttta
     9481 atgcagcaaa tgggatcaca gtggtctatg agcttgctaa gtggctgaac acttatctag
     9541 accagccgaa agtttctgcc gctgtcttgg cacaaggaga agctttattc tcgcaatggc
     9601 tttcgatctt cggtatttta tttacagcag aagagttatt agatgaagag attgaacaat
     9661 tgatcgaaga acgaaatcaa gcaagaagca atcgtgattt tgtccgaagc gacgaaattc
     9721 gtgatttgtt gaaagaaaaa gggatcttat tagaagatac accgcaagga acccgatgga
     9781 gaagagaagc atgagagatt acacacaatt gaacggttta gccttggctt atgttggaga
     9841 tgcgatttac gaaatctatg ttcgtgacca cctgattgat caaggagaaa caaaacccaa
     9901 taagctgcat cgtgcggcaa cgaattatgt ttctgcgaat gcacaagcct ttttgattca
     9961 gcaaatgctg gaagaacatc ttttgacaga agaagaagaa ctttattatc gcagaggaag
    10021 aaatgctaaa agccatacga gcgcaaaaaa tgctgatgtt acgacgtatc gggtcgcaac
    10081 agggttcgaa gcgctcatgg gctatctgca tttgacaaaa caaaccgagc ggatggaaga
    10141 attgatccgc tggtgtattc agaaagttgg tgaaaaaaat gggtaaagaa agaacaaaca
    10201 aacatcaatc gaaacgtgga tttgaagaca aaaaacaaaa tagatattca aataaaaagc
    10261 aaactggacg aaatcagtca gtttctgatc aaaatgaaga agcattagaa gataatttcg
    10321 tctttgggca ccatgccgca gtagaagcgc tacaacaagg gcgagggaat aaactctttc
    10381 ttcaagaaga ttcacgagga gaaaaagtag aagaactgaa agaaatcgca cgtgaacaag
    10441 ctgtgccagt caaatgggtt cctaaacaaa aattagaaac tttgagcgat cacggcgtgc
    10501 atcaaggagt cgttcttgcg attacacctt atgaatattt atcccttgac caactgattg
    10561 aacgaacaaa agagaaaaaa gaagacccct tctttttgat tttggatagc atcgaagatc
    10621 cacacaattt tgggtcgatt ttacggacag cagacgcaag tggcgtcgat ggtgtgatca
    10681 taccaaaaca ccgagcagtt ggaatcacac ctatcgtaac aaagacttcc actggggcag
    10741 tcgaacatgt ccctgttgca cgcgtgacga atttggtaca agctgtgcaa cagctcaaag
    10801 aaacaggatt ttgggtattt ggcacagata tgaccggcac aaacttccaa aaatggaatg
    10861 ccaaaggatc aattgcttta gtcattggta atgaaggcaa aggaatgagt ccaggattga
    10921 aaaaagaaat ggatgaattg ctgacgatcc cgatgaccgg gcacgtccag agcttaaatg
    10981 ccagtgttgc tgctggtttg cttatgtatc aggctttttc ccaacgtcag ggggagtaga
    11041 ccatgaaaaa acagctgttg attgtagacg gctacaacat gattggttcg tggccggaac
    11101 ttgtccagct taaaaagcag gacaaaatgg cggatgcaag agaagctctt ttacatcgtt
    11161 tatcaaatta tgcgaaatat gaaggaatgg aagtcatcgt tgtcttcgat gcccaactag
    11221 ttccgggcat ccaacaaaat tataagaaat accagttgga tgttgttttt acgaaagaag
    11281 acgaaacggc tgacagttat atcgagagaa tcgctggtca gctgaatgac cgtttgacac
    11341 aagtgacagt ggcgacaagc gatttagcag aacagtggat gatcttttcc caaggagcat
    11401 tacgaacttc tgcttatgaa ttatataaga cgataaaaaa aacggaaaaa acaatagccc
    11461 aagaaaataa agatatgcat tttattgatt tccgacgtaa ttctccatgg aatgaagagc
    11521 agttaaaaaa attgtcccaa aaattggacg atttaatgag aaaaaataaa taacatatcg
    11581 ttctaatcag ttcgatgaat cattgatgat aagattcctc cataaacgaa tttatggagg
    11641 aattatttta tgtctgagga gttattgcgc gctgcacgta atggtgacga agaagcattt
    11701 gctgccctgt atcaaaaata ttttccactt ttactacgtt tgaaaaacac ctattattta
    11761 agaaattatg tttctgagga ttgggaacaa gaagcaagga tcgctttata tcaggcattg
    11821 agaacttacg aaaaaagcaa aggtgttagc tttggaagtt attataaaag cattataagc
    11881 aatcaaatct attctctgtt gaggaagcag aacgcgctga agcgtcgtga tcaaaaagat
    11941 gaagtctcaa tcgaccaaaa aatagagaca gaaggaccag actttttagc agagatcaca
    12001 ttgcaagaac ctttagcgat tcagcatctt ttattaaaag aagcaatcga aaattgcgaa
    12061 atccagtttt caaaaataga agctaaaatt tttcattatt atatgcaagg cgttgatttt
    12121 gtagacatgg ctgaatgttt agcaatggat cacaagcaag taatgagcgc ttacgggaga
    12181 gtaaaactca aaataaaaaa acacttgaaa ttttataatg aggaataatt tagaaaaatc
    12241 ttaatgagct tcttatttat tttta
//
LOCUS       DADVXB010000080        12139 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.082, whole genome shotgun sequence.
ACCESSION   DADVXB010000080 DADVXB010000000
VERSION     DADVXB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.082"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(69..626)
                     /gene="frr"
                     /locus_tag="KB902_001772"
     CDS             complement(69..626)
                     /gene="frr"
                     /locus_tag="KB902_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBB6808597.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(629..1351)
                     /locus_tag="KB902_001773"
     CDS             complement(629..1351)
                     /locus_tag="KB902_001773"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBB6808598.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1487..2368)
                     /locus_tag="KB902_001774"
     CDS             complement(1487..2368)
                     /locus_tag="KB902_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBB6808599.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2467..3249)
                     /gene="rpsB"
                     /locus_tag="KB902_001775"
     CDS             complement(2467..3249)
                     /gene="rpsB"
                     /locus_tag="KB902_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBB6808600.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3608..4087
                     /locus_tag="KB902_001776"
     CDS             3608..4087
                     /locus_tag="KB902_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBB6808601.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4304..5395
                     /gene="phnW"
                     /locus_tag="KB902_001777"
     CDS             4304..5395
                     /gene="phnW"
                     /locus_tag="KB902_001777"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBB6808602.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5388..5516
                     /locus_tag="KB902_001778"
     CDS             5388..5516
                     /locus_tag="KB902_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6808603.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5520..6065
                     /locus_tag="KB902_001779"
     CDS             5520..6065
                     /locus_tag="KB902_001779"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6808604.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6519..8210)
                     /locus_tag="KB902_001780"
     CDS             complement(6519..8210)
                     /locus_tag="KB902_001780"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBB6808605.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8630..9577)
                     /gene="arcC"
                     /locus_tag="KB902_001781"
     CDS             complement(8630..9577)
                     /gene="arcC"
                     /locus_tag="KB902_001781"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBB6808606.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9692..10711)
                     /gene="argF"
                     /locus_tag="KB902_001782"
     CDS             complement(9692..10711)
                     /gene="argF"
                     /locus_tag="KB902_001782"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBB6808607.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10802..12031)
                     /gene="arcA"
                     /locus_tag="KB902_001783"
     CDS             complement(10802..12031)
                     /gene="arcA"
                     /locus_tag="KB902_001783"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBB6808608.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3322 a         2524 c         2199 g         4094 t
ORIGIN      
        1 taaataaaag aaatataaat aaaaacagag gaagcggaat gatccgcccc tctgttttta
       61 tgattttatt aaacttccaa taattctttt tctttatcag cagcgatctt atctacttct
      121 ttgatgctgt tatctgtcaa tgtttgtacg tctttttcta atccgcgcaa atcatcttcg
      181 gtaatatcac catttttttg ttgtttttta tattcatcga tcgcatcacg acggatgtta
      241 cgaatcgcga tttttgcatt ttctgcttct tttttaacat ctttagctaa ttcttttctg
      301 cgttcttctg tcagttgcgg gataactaag cgaatgacat ttccatcatt ggttggactg
      361 attccgatat cacttgccat aatagctttt tcaacatctt gaagaatgct cttgtcaaaa
      421 ggtgtgatca ttaaaacacg tgcttctgga atttggattg atgccatttg gttcaatggt
      481 gttggcgcac cgtagtagtt cacagtaata cggtccaaaa ggctagcgtt cgcacggcct
      541 gcgcggattt gcccaagttc acgttgaaga ttttgtgctg cttttttcat tttttctttt
      601 gcttctgtca taattgcatc tgccattttt atttccccct tacagttgtt ccgatatttt
      661 cgcctaagat tgcacggcga atatttccgt gttcatttaa attgaagaca agcagtggaa
      721 tatcattatc catgcttagt gaacttgcag ttgaatccat gacttgtaat cctttggcaa
      781 taacttccag atgagtcagt tcttcaaatt ttactgcatt tgcatctact ttcggatcag
      841 cagaataaac accgtctaca ttgtttttag ccatcaggat aacatctgcg ccgatttctg
      901 ccgcgcgtaa tgctgctgtt gtgtctgtcg agaagtacgg gttgccggta ccgcctgcaa
      961 agataacgat ccgtcctttt tctaaatgac gttctgcttt acggcgaata tatggctctg
     1021 cgatttgacg catttcaatc gaagtttgca cgcgtgtcgg tacacccacg ttttccaacg
     1081 tatcctgtaa agctaaggca ttcataactg tagctaacat acccatgtaa tcagcttgag
     1141 cacgttccat gcccatttgt gctccgattt gtccgcgcca gatatttccg ccgcccacaa
     1201 cgattgccat ttcaacgccc agctcgtgaa cttctttgat ttcttggatg atttctttga
     1261 ttactggtgg tttgattcca aatcctgcgt ccccagctaa agcttctcca ctcaatttta
     1321 agactacacg ctgatatttc ggtgtgacca tgttcattcc tccaatattt tctattgcca
     1381 ttttaccata cttagatgat ttcgacactc taagactggt ttttcttgtt ttgcttaaaa
     1441 aaagggagcg cacaaaccgt gcgttcccgt ctgttattca acagaattat tttttcactt
     1501 ggctcataac ttcttctaca aagttatctt cgcgtttttc gataccttcg ccaacttcga
     1561 aacgtacgaa tgttttaaca gttgcgcctt ttgatgcaac gtatttttca acagtcatat
     1621 caggatcttt aacgaatggt tggtccacca aagcgatttc tgctttgaat ttcttcaagc
     1681 gtccttctac cattttttca acgatattcg ctggtttgcc ttcgttcaat gcttgttctg
     1741 taagaacagt tttttcatgt tctaattcag cttctggaat ttgtgattcg tttacataac
     1801 gaggattgat agctgctacg tgcatagcta cgtctcttgc aactgtttcg tcagttgttc
     1861 catctagaac agtcaatacg gcaatacgtc cgcccatatg caagtatcca ccaaatgcag
     1921 cattgtcgtc tttttctaca acttcaaagc gacggaagct gattttttct ccgataactt
     1981 gagttgcttc gatcaagtca gattcaattg tacctttatc tgttttgatt ttcattgcag
     2041 cttccatgtc tgctggtttg ttttcagcaa caagttctgc aatttctttt actaaatctt
     2101 ggaacatttc gtttttagaa acaaagtctg tttctgagtt tacttcaacg attgctgcag
     2161 tgttaccttt cacagcaact gaagccaatc cttcagctgc aatgcggtca tttttcttcg
     2221 cagcctttgc cattcctttt tcacgtaaaa gatcaactgc tttttccatg tcgccttcta
     2281 cttcaactaa tgcttttttc gcatccatca ttcctacgcc agtcatttcg cgtagttctt
     2341 ttaccatttt agctgtaacg tctgccatgt ttaactcctc ctgtgtgttt ttctttttaa
     2401 aaaaagctgc ttcaaaggag agtgaggctt gtcgcccagc ctttgaaaca gctccatcat
     2461 tcaaaattat tctgctgaag aattgtcgcc ttcaacaaca tctacgattt cttcgattga
     2521 tgttgctgtg ttttcttctg tgaaatcttc ttcaactact tgatcttcac cttggtttcc
     2581 ttcgatgaaa gcatcagcca tttttgaagt aatcaattta acggcacgaa ttgcatcgtc
     2641 gtttgaaggg attactacgt cgatttcatc tggatcgcag tttgtatcaa ccatagctac
     2701 gattgggata tttaatttgt gtgcttcttg aacagcaata cgttctttac gtgggtcaac
     2761 gatgtacatt acatctggga ttcttggcat atcagcgata ccgcctaaga atttttcaag
     2821 acgttcacgt tctttgttca aaccagcaac ttctttttta ggtagaactt caaaagttcc
     2881 atcttcttcc attgcattga tttgtttcaa acggctgata cgtttttgga tagtatccca
     2941 gtttgtcaat gttccgccta accaacgatg gttaacgaag tattgtcctg cacgagttgc
     3001 ttcttctttg attgcttctt gtgcttgttt ttttgtacct acgaataatg ctacgccgcc
     3061 ttcttcagca acgctcttca tgtaatcata agctgcatct actaatttaa ctgttttttg
     3121 caagtcaatg atgtagattc cgtttctttc tgtgaagata tatttcttca tttttggatt
     3181 ccagcgacga gtttggtgac caaagtgtac gccggcttct agtaattgtt tcatagaaat
     3241 tactgccatg tttgtttcct ccgatttggt tttatttttc ctcttcttat cttctacctt
     3301 gccggcaaac tttttcaagc acctaccgac aatccaataa gaatgtggat ttgctgatgc
     3361 ataaagcacc ctcagctatt atacagacaa aagatccgta tcgcaagagc aaatatactt
     3421 ttctgctcaa cattcaatag tttacctgaa agataaaaag aattcaagaa aaacagtaga
     3481 tttctctttg tttctttatt atcctttttc cataaaataa ttttaggtat aaaagacgaa
     3541 tattattggg caatccttct tttttttgtt atgatacatg tgaaatcttt cgtaaaggag
     3601 aaagaaaatg cgcaaagctc aaagacattt gctgattaaa caagtcattg aagaattccc
     3661 gatccgtacg caagaagaac tattaaacaa acttgggcat tatggcgtta ccgccacgca
     3721 ggcaacgatt tctcgagata tccgtgatct aaaaatcgtg aaggcacctg atgaaaatgg
     3781 cgtttcccgc ttcgtattgt ttcgcgaaaa aggaactcct gagactagga ctgaggaaga
     3841 ggatcggctg gttcaaatga ttgaagacat tgtattgaaa gtcgaacgag tccacttttt
     3901 gacgatcgtc aataccttgc cagacaatgc tcatttattt gcatctgttt tagatgagat
     3961 caaacctccc tctattgtca gtacaattgc tggattcgat acgatcatgg tcatctcgga
     4021 aaatgaggag gacgcaaaac gagtagaaga atttcttcac catccaactg aagtatcact
     4081 tttttaatca gagcacgtat tcctaatatg gaatgcgtgt ttttttattt tcaatatttt
     4141 ccttattgaa taaaccttta cactctttac aaaaatacat cattttttat tcaaattttt
     4201 caacaccttg attgaatcac aataatcatc atttatattg gatgttaaca agagcagctt
     4261 cttgctcttt gtgtatttca aaaaagaaat gaaaggaaat catatgtata aattattaac
     4321 ttctggacca ttgacgactt ctgaaacagt gaaaaatgct atgctgatcg atcattgtac
     4381 ttgggatcaa gaatacaaag aaattacaca atggataaga aaaaaattat tggatcttgc
     4441 tcaagtatcg gaaggaatat acacaacggt cttaatgcaa ggtagcagct ccttcggggt
     4501 agaatcggta ttaagttctg tgatcaggcc agaagatact gtactgattt gttcaaacgg
     4561 cgcatataga caacgaatga tcaacatgtg cgaatgtctg aaactgaact ataccgttta
     4621 tgaggtatcg gaacatcaaa tcctccaagc tcatgtgatt acacagctga ttgaagagaa
     4681 tccgtctatc tccgcactag caatggtcca tagcgagact acttccggta ttttgaataa
     4741 tttggaagag attgctgctg tcacacaaga aagagatctt ttgtttatag tggacgcgat
     4801 gtcaagcttt ggtgggatac cgatttgtgt agccgaacta gggattgatt ttttgatttc
     4861 cagctcaaac aaatgtattc aaggtgttcc aggcttttct tttgtacttg ctaataaagc
     4921 ggaactggaa aaacgaaaaa atgttagccg aagtttgtca cttgatctat atgaccagta
     4981 ccgcgtgatg gaaaacgaga atggcaaatg gcgtttcact tcccctaccc atacggtttt
     5041 ggcttttcaa caagcgctga aggaactaga ggcagaagga ggaatcgaaa ctcgatattc
     5101 acgttatctc gccaataatc atgtgctacg acaaaaaatg acagagatgg ggttccagcc
     5161 tttcattcaa gaatatcagg ggccattcat cacctctttt ctttacccta aggactggcg
     5221 atttgatttt aatcattttt atcagtattt aaagcaaaat ggatttgtga tctatcccgg
     5281 gaaaatcagc gatcatgaat gttttcgtat cggaaatatt ggcgagatct atccggaaga
     5341 tattttggaa ctgacagcaa ttatcaaaga ctataaggag aacgttaatg attaaaactg
     5401 taatttttga ttgggcagga acaactgtgg actttggctg tatggctcct gtccacgctt
     5461 ttagaaatgc ttttctagaa aaaggaatcc aactgactga caaagaaatc cgctaaccga
     5521 tgggaaaatt aaaatgggat catatccaac agcttctttc cctcccttct gtcaaaaaac
     5581 aatggatagc tatttatgga caactacctc aggaaaaaga ggtggaggaa ttgtatcaac
     5641 aatttgaaca ttatctgttt aaagatttgg tcaagcattc taccttgaaa cccgacacat
     5701 tggaaacgat cgaacggttg agaaacgctg ggatcaatat tggttccacg aatggattta
     5761 atgctcctat gatgacaatc gtagcagaaa ccgcaaaaaa agaaaggtat tcaccagact
     5821 tcatggcaac ttttgaagac gtcgaagggt atggtcgacc gtttccttat atgatccata
     5881 aaaacatgca gtacttcaaa aacaagtcgg ttgatgaagt aatcaaagtc ggagatacgg
     5941 tctcagatat ccaggaaggg aaaaatgccg gagtgttgac agtaggtgta attgaaggta
     6001 gttcgctaat ggggatttct tatgatgagt accaaaaatt agagatgggg aaaaagatcg
     6061 tttaaaacag tctgttgctc ttagattcca acaagccggc gctgatattt gtgtaaacaa
     6121 tttaaaagag ttaacagaat acattttgta cgctgacatg aatccagaat gacttttata
     6181 caaaataaga ggttgtgaaa aagctgtcct gtatcaagta ataaaaacag ccaagcaaaa
     6241 atagctcctc atatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca
     6301 ccgtttattc gaaaaaaaaa agggagctgt gacacgactt ttgtcacagt ccccttattt
     6361 gcaaacaaac agtgtttaag agacaacctc tccactaaac ggtgttcatt cagctgactc
     6421 tcggtatttg ctcaaaaaac gataaaattt gaaaagctat tttctctttt gtttctctaa
     6481 tactcggatc agaacgctga tttcacattc tctttttctt acatcttatc tggtgcatga
     6541 agtcctagca aacgaaggtc ttctttcaat aatacagtca ctgcataaac tagagctaag
     6601 cgtgcttctt tttgttcatc atcagctaaa atcttcgtat gagcatagta tttgttgaat
     6661 gcttgtgcta atttgattgc atgtttcgca atcactgacg gttcgtattt ttccccagca
     6721 gacaagaccg tttcagggta tttttgaact aatttaacca cttcccagct ggtatcgtca
     6781 ttcaatgcat agtctgctgt ttctgaaggg acaaatcctg ctttttccaa caggctgact
     6841 gcacgagcat gtgtatattg cacataaggt ccagtttctc cttcaaatcg aacaacttct
     6901 tccaggttaa agtcaaatgt attcagtcga tcgtttttca aatcgtggaa aatgactgcc
     6961 ccaaccccaa cttgtttagc tacagcatct ttgttttcca aatcagggtt tttctcgctg
     7021 atttgttctt tagcagattg gattgcttca tttaatactt cttctaataa gacgatcttt
     7081 cctttacgag ttgataattt tttaccacct tgcgtgatca aaccaaatgg aatatggtgc
     7141 atgtcgtcag accagtcaaa gcccatttcc ttcaagacag ctttcaactg tttaaaatga
     7201 tagctttgtt cattccctac tacatataga gattgtttga agtcgtaagt acgtttacgg
     7261 tacaatgcag cagctaagtc acgtgtaatg tatagtgtcg caccgtctga cttcttaatc
     7321 aacgctggat tcaggtcata agcagatagg tcaacgatct ctgcaccttt atcctcgttc
     7381 agcaaatgtt tttcttctaa aagtttgacg atttcatcca tcttgtcatt gtagaaagct
     7441 tcaccgttca acgaatcgaa acgtacttcc agcagatcat agattttatt gaattctttc
     7501 atcgattcat cacggaacca ttgccataat tgaatagcct ctttatcgcc ttcttccaga
     7561 cgtttgaacc aagcacgagc ttcttcattt aattctggtt ctgtttcagc tacttcatgg
     7621 aattggacgt ataaacgaag caattcattg attggttctg ctttaacagc ttcttctgta
     7681 ccccattttt tgtaagcgac gatcagtttt ccaaactgtg ttccccagtc acctaaatgg
     7741 ttgatgcgga ttggctgata accgattttt tccataatga aaccgatcga attaccgata
     7801 actgtcgaac gcaaatgtcc cattgagatt ggtttggcaa tattaggaga agacatgtcg
     7861 attggtactg ttccttgatt cccgatgttg ctatccccat aatgttcttt ttctttcact
     7921 actgtttgca aaactttttt gctgataagt tctttattca tgaaaaagtt caagtaaggt
     7981 ccgacaactt cgattttttc aaagttggca gaatcgattt tttctgctaa atctgcagcg
     8041 atttgctgtg gcgcttttcg gtaaactttt gctaatgaaa aggctggaaa tgcaacatct
     8101 ccgtgttcag ctgattttgg attttctagt aattgctcga cttgttccag tgttaaatca
     8161 tctttgacag cgtcatagac agcttttgcg acaagatctt tattattcat ctttattcct
     8221 cctaaagtgt tcccttgatt gttaaacaaa aaaaatctct agcgacggca tacttagtat
     8281 gccatcacta gagacgagat ttcccgcggt accactccaa ttgtcctaaa aaaggaccag
     8341 ctccatctga tatcggtaga cgaccgtctg tttaaaacag aattctccaa gtgcgcttcg
     8401 ttgtatcttc ttcattcggc ttccaccact tccgaattcg ctagccaaga atgatacaag
     8461 tactctcttg ttcaacaaat cttagtctta ttaaactttc ttgaattata tcagaaaaaa
     8521 aaacgaaagg ctagtcgttt cataaaaaaa caatccagat ggcctaaagg agaagaaata
     8581 ccacctggat agctataaat catttcgtaa atacgaaaga cttaacaaat taatcagcta
     8641 cgataatcgt tccttcttca gaagctaaaa gattctcgat attttctaaa gaagtgatga
     8701 ttgccttagc gtttggtttt gcttcaacaa atgcaatagc tgcttctact ttcggaagca
     8761 tgcttcctgg agcgaattgc ttttcatcaa tgtattgttt catttctgaa acagtaacag
     8821 tttctaattt cttttgatct ggtttttggt aattgacata cacattgtct actcctgtca
     8881 atacgatcag caaatccgca tcgatgattt cggctaattt ttctgaagca aaatctttat
     8941 cgattacggc ttctcgtcct tctaatccag tagctgtttc tacaacagga atcccaccgc
     9001 caccaacaga gactgtgata actccttgat cgaccagcgt ttcgatgaca cgtgcttctt
     9061 taatcgagat gggtttaggg gaagcgacta cttttctcca tccacgtcca gcatcttctt
     9121 tgaatgtcac agtggagtca gcattcattt gttctttggc ttcttcttcc gtgtagaatg
     9181 gaccgactgg tttacttgga tttttgaatg aaggatcatt ttcatccaca ataacttgag
     9241 tgactaaaga aaccacatct ttatcgatcc ctttttcctt cagtacttcg cccatggcgt
     9301 tttgtaacca gtaaccgata gatccttctg tcattgcaac acatgtatct aaaggcattg
     9361 ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa taggttaccg acttgcggac
     9421 catttccgtg ggagatgatc aattcatctc cttgttcgat aaatttcact aaatactttg
     9481 ctgtttccat taacgcttct tgttgggctt ttgcacttgc atccgtagac aagatggcat
     9541 tgccccctaa agcgacaact acttttcgtt tggccatttc attcgtcctt tcttcagttc
     9601 taccgaattt tctagataac aaaacgagcc agcgttttgt gattttccct caatgctgac
     9661 tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg agggataaac aagttaccta
     9721 atgttgctgc catgatcgct ttgattgagt gcatacgatt ttctgcttgg tcaaattgac
     9781 gagcatattt gctgcggaag acttcatctg ttacttccat ttcagtgatg ccaaagcgtt
     9841 ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa agctggcaag cagtgcaaga
     9901 agatcaaacg atctgtgttg tgtgtttttt ctaccatttc catattgatt tggtaaggtt
     9961 tcaacaattt gatacgttct tcgaatttat cttcttcacc cattgatacc catacatcag
    10021 aataaaggac gtctgctccg tctacacctt tatcaacatc gtcggtaatc atcaattgtg
    10081 caccggattt ttcagcaaag ccttctgcca ttttgacgat ttcttcttca ggttgtaatt
    10141 cttttggtgc aacgatacgc atattcgctc ctaaaattgc acctgtgact aataaagagt
    10201 tagccatatt gtttcgacca tctccgcagt aagcaacagt gataccttct actgttccaa
    10261 agttttcttg gatagttaaa aagtcagcga tcatttgtgt tggatgccat tcatcagtca
    10321 agccattcca aactggaaca ccagagaatt ctgctagttc ctctaccatt ttttgactga
    10381 atccacggaa ttcgattccg tcaaacatac gtcctagtac tttagctgta tcttctgtgg
    10441 attctttttt acctaattgg atatcatttg cacctagata ttcaggatgt gcacctagat
    10501 cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga tgttttttca aataaaagcg
    10561 caatattttt tccttctaga tagtgatgtg ggataccacg ttttttcaag tctttcaagt
    10621 gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt aaagtctttt tctgctaata
    10681 agcttcttcc ttggaatact gattctttca tattaaacat tctcctttag attgttttta
    10741 tttaagatta aagaggaaat cccgacggca gctgacagta agactgccgt caggaaacaa
    10801 attacttcaa gtcttcacgg acaagtggtt ggctcatgca gcgtggacca ccacgacctc
    10861 gtgacaattc acttgaattg atttctaaca ctttgatgcc atagctacga agcaattcgt
    10921 tcgatacata atttcggtta taagtgacta caacacctgg agcgattgcc aatgtgtttg
    10981 atccatcatt ccattgttct cgaggtgcaa cgatctcatc tccattacca gttgggatca
    11041 gtacaagatc atctaatcca agagcagctt tcatcgtttc gtgtaagtta tctgaatgag
    11101 taatcttgat atcatcacca tctggttcga ttgtaaagac atccatctta ccgtctttac
    11161 tttgaattgc tggatggata gtgaatttat cgtgatctac cattgtaaat acggtatcca
    11221 aatgcatcat tgcacggttg ttcggaattt tgattgccaa cactttttca aatcctgaat
    11281 tttttgcgaa taggtggcgt gctaattttt ctaaagcttt cgcattagtt cgttgagaaa
    11341 tcccaacagc tactacttta tcgcttaaga tcaattcgtc tccgccttcg atatgatctg
    11401 gattttcacg atccaaccat acttcgattc ctttatttgc aaatcttgga tgatgtttca
    11461 aaatatattc tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc ttattgactg
    11521 tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt ggcattgggt
    11581 ccatgtaaaa tggatagtca tcgtctgctg acagatcata tagactgcta gaacgtactt
    11641 cgatatcttt tgtacgaacc ccagccatga ttttatctac catttcttgc gtttccattg
    11701 atagaaggaa ctcatgaaga ccctctctta cagcattcga tgcaatatga gattcatcca
    11761 acattttatt caagaattgt tctttgacat tgcctgcgtc aatcgcttct gccgctaatt
    11821 tttccaagta aagagtctcg acgccttcat tttgcaatgt cttcgcaaag ttgtcatgtt
    11881 cttcttgagc aatcggaaga tatggaatat catcgaacaa cagacgatcc ataatatctg
    11941 gtgtcaaatt ttccacttct tgtccaggcc gtttcagtaa aactgtcttt aatttcccta
    12001 tttcagagaa aacgtgaata ggtttatcca tgttgtgttg cctccttctt tttgattaca
    12061 tgtataggat atcctccttt tgtaatcact ttcataattt tgtctcattc aaaatgagac
    12121 attcctcaca ttaatattc
//
LOCUS       DADVXB010000081        12013 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.083, whole genome shotgun sequence.
ACCESSION   DADVXB010000081 DADVXB010000000
VERSION     DADVXB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.083"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1168
                     /locus_tag="KB902_001784"
     CDS             <1..1168
                     /locus_tag="KB902_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6808609.1"
                     /translation="GKVEIEFFNQKKEMTQTIQEIAKDFEAKNPDIHVKVVDVPNAGE
                     VIKTRMLAGDVPDVINLYPQSIELKEWAKAGYLEDLTEEPYLENIKNGYAQRFAIEDR
                     VYSIPLTANVYGFYYNKTAFEEMGIQAPETWAEFEKIVAEIKDQNKVPFAIAGAEGWT
                     LNGYHQLAIATAAGGEEEANNVWRFSEVNGINAESKEMQKDFNRLDLLREPKALQNNW
                     QGAGYNDTVVTFTKGDALIMPNGSWAMPMIHSQNPDFEVGTFPFPADEAGQSLTIGAG
                     DLALSVSATSQHKEEAKRFVEYMTTPEAMQKYYDVDGAPCAVEGVIENTQDSPLSGLT
                     ELAFTDRHLVWLAKDWNSENDFYTLTTNYLHNGNQKAMINALNAFFNPMKADGR"
     gene            1178..2050
                     /locus_tag="KB902_001785"
     CDS             1178..2050
                     /locus_tag="KB902_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6808610.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            2062..2892
                     /locus_tag="KB902_001786"
     CDS             2062..2892
                     /locus_tag="KB902_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6808611.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            2932..5115
                     /locus_tag="KB902_001787"
     CDS             2932..5115
                     /locus_tag="KB902_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6808612.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLQERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            5176..6396
                     /locus_tag="KB902_001788"
     CDS             5176..6396
                     /locus_tag="KB902_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBB6808613.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKYSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVCLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            6393..7853
                     /gene="gtfA"
                     /locus_tag="KB902_001789"
     CDS             6393..7853
                     /gene="gtfA"
                     /locus_tag="KB902_001789"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBB6808614.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVTQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            7930..9036
                     /locus_tag="KB902_001790"
                     /pseudo
     CDS             7930..9036
                     /locus_tag="KB902_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            9358..9567
                     /locus_tag="KB902_001791"
     CDS             9358..9567
                     /locus_tag="KB902_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6808615.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            9560..9709
                     /locus_tag="KB902_001792"
     CDS             9560..9709
                     /locus_tag="KB902_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBB6808616.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            9863..10528
                     /locus_tag="KB902_001793"
     CDS             9863..10528
                     /locus_tag="KB902_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6808617.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(10812..11897)
                     /gene="xerS"
                     /locus_tag="KB902_001794"
     CDS             complement(10812..11897)
                     /gene="xerS"
                     /locus_tag="KB902_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBB6808618.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         4053 a         1832 c         2298 g         3830 t
ORIGIN      
        1 cggtaaggta gaaatagagt tttttaatca aaaaaaagaa atgactcaaa cgattcagga
       61 gattgctaaa gattttgaag caaaaaaccc tgatattcat gtaaaagttg tggatgtacc
      121 gaatgctggt gaagtaatta aaacacgtat gcttgcaggc gatgtaccag atgtcattaa
      181 tctttatcct caaagtatag aattgaaaga atgggcgaaa gctggttatt tagaggactt
      241 aaccgaagaa ccgtatttag agaatatcaa aaatggatat gcacaacgtt ttgctattga
      301 ggatcgtgta tatagcatac cattaaccgc taatgtctat ggtttttact ataacaaaac
      361 tgcttttgag gaaatgggga ttcaagcacc agaaacttgg gcagaatttg aaaaaatagt
      421 agctgagatt aaagatcaaa acaaagtacc gtttgcgatt gcaggagcag aaggctggac
      481 tttaaatggt tatcaccaac tagctatagc gactgctgct ggtggtgaag aggaagcgaa
      541 caatgtttgg cgtttctcag aagttaatgg aattaatgct gaaagcaaag aaatgcaaaa
      601 agattttaat cgattagatt tgttaagaga accaaaagct ttgcaaaaca actggcaagg
      661 tgccggttat aacgatacag tagttacttt tacaaaaggt gatgcgttga ttatgccgaa
      721 tggttcatgg gcaatgccga tgattcattc acaaaatcca gattttgaag taggaacttt
      781 tccttttcca gcagatgaag caggtcaaag tctaacgatt ggcgcaggag acctagcctt
      841 atcagtttct gcaacttctc aacataaaga agaagccaaa cgttttgtag aatatatgac
      901 aacacctgaa gcgatgcaga aatattatga tgtagatggt gcaccgtgtg ctgttgaggg
      961 cgttatcgag aatactcagg attcaccatt aagtggttta actgaacttg cttttactga
     1021 tcgtcattta gtttggttag ccaaagattg gaatagtgaa aatgattttt ataccttaac
     1081 aacaaattat ttacacaatg gcaatcaaaa agccatgatt aacgcattaa atgctttctt
     1141 taatccaatg aaagctgacg gaaggtagga aaataaaatg aaaataaaag aaattttaaa
     1201 tcgttactgg gcaatcattt ttgtagcaat tccaattatt ttgcagatga tttttttcta
     1261 ctttccaatg gttcaaggtg ctttttacag tttaactaat tggactggtc tgacttataa
     1321 ttttgatttt gtgggtttga acaattataa gattcttttt tctgatccga agtttatcaa
     1381 atcgattggc ttcactttaa ttgtgacgct ttgcatgatt gctggacaaa ttggttttgg
     1441 tattttgatt gcgcgggcgt tgaacgcaaa tattaaaggg aaaacattct ttagagcatg
     1501 gttctttttt ccagcggtct tatcgggcgt ggttgtttct ttagtattta aacaaatttt
     1561 taactatggt ttaccaaaaa ttggtagtat gttaggcatt gaatttttac aaaccagtct
     1621 tttaggaaca acatggggag cgatttttgc agtaattttt gttttacttt ggcaaggaat
     1681 tgccatgcca gtcatcattt tcttagcggg ttttcaaagt attccacaag aaattattga
     1741 agctgctaga atggatgggg cgaatgataa gcaaattttt tggaatattg aaatcaccta
     1801 cttattacca agtatttcaa tggtatttat tatggcatta aaaggtggct taacagcatt
     1861 tgatcaaatt tttgctttaa ctggtggtgg accaagcgat gccacaacat ctttggggtt
     1921 acttgtttat aattatgctt ttaaaaacaa tcagtttggt tatgcgaatg ctattgcttt
     1981 agtcttattt atcttaattg ggattgtttc actggcacaa ttaaaattat cgaaaaaatt
     2041 tgaaatctag gaggtttccc aatgaaaaca tcaaaagaaa aaaatatttc taaatacttg
     2101 cttttattat tagggggctt catgatttta gttcccttag tttcaacgct attcggttca
     2161 tttaaaacaa cacccgatat tatgaataat ttctttcgtt ttcctaatcc agcgactttg
     2221 gaaaatttcc gaagattgtt agcggatgga attggtcatt acttttggaa ttcggcaatc
     2281 atcacaatca ttgcagtagt tgctgtgaca gcaattattc ctatggctgc ttattcacta
     2341 gcaagaaaaa tgactcgtgg gaaagcatac ggattgatgt atttattttt aattttagga
     2401 atttttgttc ctttccaagt aattatgatt ccgattaccg ttatgatgag taaaattggt
     2461 ttagcaaata tgtggggatt aatcttactc tatctcactt atgccgtacc acagacacta
     2521 tttttatatg ttggttttat taaactaaat gtgcctatca gtctggatga ggctgctgaa
     2581 attgatgggg ctagtcactt tacaacttat ttcaaaattg ttttcccaat gttaaaacca
     2641 atgcatgcga cgactattat tcttaatgct ctatggtttt ggaatgattt catgctacca
     2701 ttattaattt taaatcgtga ttctaatatg tggacactac cattgtttca atataattat
     2761 acgggacaat attttaacga ctatggtcca agttttgctt cctatacagt aggaattgtc
     2821 acgattacac tagtttatct tgctttccaa agaagtatta tagctggaat gagcaatgga
     2881 gcagtgaaat aaccaataaa ttattctcat tataaaggag ttcataaact tatgattata
     2941 tttgacaatc acacacaaac atttcattta caaaataaaa aaattagcta tctattagga
     3001 atcgaagaaa ataattattt aacgcatctt tattttggaa aaaagattac gcactattct
     3061 ggtgggtatc gctacccccg aacagatcgt tccttctcac ccaacaatgc aaatgcgcaa
     3121 gatcgtttat tatctttaga tacattacca ttagaatttc caggatatgg acatggtgat
     3181 tttagagaac cggcgcataa tattaaatta ggaaacggta gtcgtgtaaa tgattttcgt
     3241 tatgatagct acgaaattca aaaaggaaag cccagcttag cgggattgcc agccttatat
     3301 acggaagatg atgatgaagc tgaaacgctg attattcaat tgaaagacgc gattagtgga
     3361 ttgactttac agttgttcta cacaatttat caaaatcaca gtgtaattat tcgttctacg
     3421 caattagtaa ataatagtga tgaaacagtg gagattaacc gcttagctag tcaatcaatt
     3481 gattttccaa atcgtccact cgagttaatt catttaaatg gtacctgggc aagagaacgt
     3541 caaatgacta gagaaaaaat tcatacaggg ataaaagtat tagatagtaa acgcggatca
     3601 agcagccatc aacaaaatcc gtttgttgct ttagtagatg ccaaaacaga tgaatttcaa
     3661 ggagaggcat atggatttaa tttagtttat agcggtaatc acgaaacggt gattcaaaaa
     3721 gatccatttg accaaacacg ggtcattatg ggaattaatt catttaattt tggttggcaa
     3781 ctaaaaactg gcgactcatt tcaaacgcca gaagtcgtga tggtttatag taatgaaggt
     3841 ctgaatacgt tatcacagac gtatcatgaa ttgtataatc accgtttaat tcgtggaaac
     3901 tatcgtttac aagaacgtcc cacgttaatc aacaactggg aagcaacgta ttttgatttt
     3961 aacgaagaaa aaatcatgaa tattgtcgat gatgcgaaga acttgggcat tgaaatgttt
     4021 gttttagatg atggttggtt tggcggtcgt gaaaatgact tcacttcatt aggtgattgg
     4081 gttgaaacag aaggcaaact tgcttgtggt ttggaaaatt tagccaagca agtgcatgat
     4141 aacgggatga aatttgggat ttggtttgaa ccggaaatga tttctgaaga tagtgaacta
     4201 tttcgagcac atccagattg ggcattgggt attccaggtc gtgaccgctc aattagtcga
     4261 aatcaatatg ttcttgattt ttcaagacaa gatgttcgtg ataatatcta tcaacaaatg
     4321 acggcgattt ttgatcgtgt accgattgat tatgtgaagt gggatatgaa tcgaaatatg
     4381 acagaagtct attctgtctt gttggactca acgatgcaag gtgaagtggc tcatcgttat
     4441 atgttagggt tatatgaatt tttagaaaag ttaacaacga attatccaac tattttattt
     4501 gaaagttgtt cgggtggagg cggtcgtttt gatgcaggtt tcttgtatta catgccacaa
     4561 acttggacga gcgacaatac cgatgccgtg gctcgtctga aaattcaata tggaaccagc
     4621 ttagtgtatc caatttcaag tatgggtgcg catgtttcag cagtcccaaa tcatcaaaca
     4681 ggaagagaaa cgagtttaac tattcgtggc aatgctgcga tggctggtgt ttttggttat
     4741 gagctagatc taacgcaatt aacttctgaa gaaaaagcag aaattaaaga acaagttgcc
     4801 ttttataaaa agcatcgcca acttttgcaa tatggaactt tttatcgctt ggaaagtccg
     4861 tttgaaggca atgatactgc atggatgttt gtctcaaaag accaaacaga agccatggtc
     4921 ttttatttcc gagtattagc agaagctgcg catccattag tcacattgaa attagcagga
     4981 ttagcagaag aagcaactta tcaaatggaa gatgtaacat ttgctggcga tgaattgatg
     5041 aatctcggtt tttatattga ctcagaacta catggtgatt atgcgacaca acgcttttat
     5101 ttgaaacaga tatagtagct tgaatttaca atataagtgc aacaccaaaa gagactcatt
     5161 ccaaacgaag aaaatatgtt ttatttacac gcatttacta aaaagcagcc tgatttgaat
     5221 tgggaaaatg aagaagtacg tgaagaaatc tatgcaatga ttaactattg gttagataaa
     5281 ggactaggcg gatttagaat cgatgcgata ttaaacatca aaaaaaaact agagtatggc
     5341 atctttgaat ctgatggaga agatgggtta gccttcattg ggccctggat tcttaatcag
     5401 tcgggcattg aagtgtggtt aaaagaaatg agagagcgga catttaaacc acataatagt
     5461 atgacggtag cagaagccga tgttcctaat gaacgtttag atgaatatat tggtgaagat
     5521 ggctattatt cgatggtttt tgattttagt tatacggata ttgatgtacc tgaaactggt
     5581 gaatggttta aatatagcca atggacatgg acggatatgc gtaccaatat ttttacgaat
     5641 caattagtta cgcaagataa aggttggggc gccttatatt tagaaaacca cgatcaacca
     5701 cgttcaatta ataaatatat tccagaagaa tggatcaatg attatagtaa aaaaatgttg
     5761 gcgacgcttt ttatgttact aagaggtacc ccttttattt atcaaggaca agaactagga
     5821 atgaccaaca tagaaatggc atcattagaa gattttgatg atgtagctac gcattctcag
     5881 tataaacggg cattagaata tggattggca ccagagcaag cattgaaagc tgtcaataaa
     5941 cgaagtcggg ataattctcg cacacctatg caatggaata cgcaaaaaaa tgccagattc
     6001 tcaacttctg ataatgtatg tttaaaagta aatcctaatt atccagaact caatgcagaa
     6061 gctcagttaa ccaatcaaca gtcggtattc aattattatc atcaattaat taaattaaga
     6121 aaaaatagtg tatacaaaga cgtgctaatc tacggacaat ttctaccagt gaaagataaa
     6181 aatgaacata ttttgcttta tgaacgccaa ttagaagata aaatcgtatt agttatctta
     6241 aacgttacag caacagaaca agaatattat gtagatgaac agtaccaaca agtattaatc
     6301 aataattatg aagatgtttt attagatcaa agtcgaaaat tgcgtttacg accgtttgaa
     6361 agtattgtat tagctaatta tggaggacaa ttatgaaaat taaaaacgaa gcaatgctca
     6421 tcacctatgc agatagttta ggaaaaaaca tgggcgaatt aaaacaagtc ttagacaaac
     6481 atttacaagg tgttattggt ggtgtacatc tgttgccttt ttttccatcg acaggtgatc
     6541 gaggctttgc gccgagtgat tatacgacag ttgatccagc tcttggaaca tgggaagatg
     6601 tggaagcatt aggtgaagat tattatttga tgtttgattt tatgattaat cacatttctc
     6661 gtgaatcaaa atttttccaa gatttcaaaa aaaaccatga gcagtcacca tacaaagaaa
     6721 tgtttatccg tattcatgaa tttttcccag aaaatcgacc aacacaagaa gatattgatt
     6781 taatctacaa gcgtaaagac aaagcgccgt ttcaaacggt agaatttgcg gatggtacga
     6841 cagaagaggt ttggaatacc tttggggaag aacaaattga tttagatgtg accaaagaag
     6901 ttgtgaaaga atttattcga gaaaccatca aagatatggc gaaccatggc tgttctttaa
     6961 ttcgattaga tgcgtttgct tatgcgatta aaaaattaga taccaatgat ttcttcgtgg
     7021 aaccagatat ttgggaactt ttagacgaag tgcgtcaaga agcagcgaaa tatgacgtcg
     7081 aattattacc agaaatccat gagcattatt ccattcaaat gaaaattgcc aatcatgatt
     7141 attatatcta tgacttcgcc ttgccaatgg tcactctgta ttcactttat agtggaaaat
     7201 cagaacgttt agccaattgg ttgaaaatga gtccgatgaa gcagtttaca acattggata
     7261 cgcatgatgg aattggtgtt gtggacgctc gtgatttatt aacagatgaa gaattggatt
     7321 acacctctga ggaattgtat aaagtcgggg cgaatgtgaa gaaggtctat tcaagtgcca
     7381 attacaataa tttagatatt tatcaaatta acagcaccta ttatagtgca ttaggcgata
     7441 atgaccgtag ctatctgtta gcacgtgcga ttcaagtatt tgcgccaggg attccacaaa
     7501 tttattacgt tgggttatta gcaggaaaaa atgatattga actgttggaa gcaacgaaag
     7561 aagggcgtaa tattaatcgt cattactatg atttagccga aattgaagaa gaagtgcaac
     7621 ggccagtgac tcaacaatta tttgcacttt taaaatttag aaatgaatct gcggcgtttg
     7681 atttggatgg aacgattgaa gtagcaacgc catcagaatc agaaatagtg attacacgta
     7741 aaaataaaaa cggtagtgat agtgcaacat taacggctaa cttggatacg aaagaattta
     7801 tcattgagtc taaagatata aaaattttca ctagtgttgc attaaaattt taacctattc
     7861 catagaacaa aaaatccttt atactagcac ttggatgact tatccaagac caataaaaag
     7921 gactcataca tggataagta taaaacaaat acagcattta ataaatggtt ttctgccata
     7981 aaattaggaa aactttctgt caactcccaa aaatgtattt ttgattacaa ttcgtatcgt
     8041 aaaaaactgt cttttgaagc tgtgctcaag ctctttctct acgcagttaa tgaagaaaaa
     8101 gaaagtttgc gtgatttgag tacagctctt atcgaccgat cgctccaact agaaaccgat
     8161 gtgtcatcga ttagtcatac ccaattgtct cgagcattta atgcacttga acctaaagtg
     8221 ttagaagaaa tttttcaaca actgttagaa aaagttcaac atcaaatcaa accaaccaag
     8281 cgaaatcatc tgtatctgat tgattccagt acgttttcgc ttagtttaaa acgtcataag
     8341 tgggcgactt tccgtcaaac aaaatcaggt gtcaagttac acttaaacta ttgttatatg
     8401 gacgatacta cgatgtatcc aactgatttt accttaacaa atgcccatga acatgatctc
     8461 aatcaactac cagtattggt gaatcaacca gaggcaactt acgtgtttga tcgtgggtat
     8521 taggactttg aaaagatgga tcagatgcat tgggatggct atttcttcgt cactcggatt
     8581 aaaaaaaaca ccaaagttca cgtgatagat actctggaaa catcgccaga aacagaaatt
     8641 ctacgagacg agctggttcg tttaggatct aaaacctatc taaccgccaa tttccgacta
     8701 gtcactgttc aagataagaa cggacgtgtg tttcaattta tcaccaatcg aatggacgtc
     8761 tcttcaaaag aaatctctga tatgtatcac gctcgttggc aaatcgaatt gtttttcaag
     8821 cacatcaaac aacacatgac cattaaaacc ttcttttctc aaagtgaaaa aggcgtgcag
     8881 aatcaattga ttttaacgat gatttccgct ctcctcacgt ttctcatcaa attggagacg
     8941 aaaacggaaa aatcagtgtt ccaaatcaaa cgattctttc gttatttact gtttcagccc
     9001 tttgaatgtt gtctagaaaa attaattccc acatgagaaa aaagaaattt ggctcgttac
     9061 ttttggtttt cagttgaata acagataaaa aattttctgg aaaaagtcat cctctgcgtc
     9121 agcacagttt tttttgactt attttcagag gaaatagttt tcagaatatt ctaaaatgtt
     9181 ttatgcaaca ctagtgatat tttttagaat tagatttcta atgtgcattt tttgagtatt
     9241 aaggagcaag tatacaaaga tttataaagc tgattaaatt tgaataaaaa tatgcaggaa
     9301 cgctactatt tttagtagtg ttctttttta tatttgaata aaaaatgtgg tggttaaatg
     9361 gtggttataa caaaaaatga attaatgaaa ttaggttatg ggaagtatca gtctgagaga
     9421 atcatacgac aggcaaaagc aattatggtt tcaaaaagct atacctatta cgaaaataga
     9481 agattaggac tagtacctgt tgaatctgta gaagaagttt taggtatgaa gatagaggta
     9541 gaggaggatt ttcagaatca tggttaattt taaaaaagat aaaaatggga aatatcattt
     9601 tactgctagt ttgggattcg acaaacgaac agggaaaaga gtacaaaaaa acgtagaggg
     9661 gttaaaacag ttaaagaaga aaaaaagcgt ataccgaact tgtttctaat tatggaaaag
     9721 aagcagaaac ttctcaaagt actatgttgt ttgaggagtt tttttataaa ttattcctac
     9781 cttattatca agggaaagta gaagaaagaa catataaaaa tcggttatct acaatcaaaa
     9841 aaacttttct tatttcttta aaatggagtt aagagaaata cgtccaattg acattcaaaa
     9901 gtggcaaaat aatttattga gcaaatataa aaattcttat gtaagaaaca tgtatgggat
     9961 ttttcagatg tcattagatc gagcagttgt tttgggacta cttgaaaaaa atcctgcaaa
    10021 agttattgga aatgtgaaga aaaggaaaac tacagttgat ttttggacaa aagaagaatt
    10081 tacaaaagtt atttcaactt tttatattga tgatttgtac caacattttg gttttatttg
    10141 tatgtggtta ctttttatga ccgttatgcg tttgggagaa gccactgcat taacttggaa
    10201 agatattgat tttgaaaata aaaacttgcg tgtgaataaa acactctatt ataagagagc
    10261 caaaacctat gagtttgtag aacccgaaac ggcttctagt attcgtacaa tcgaactaga
    10321 cgacaataca attacctttt taaaagcttg gaaggagcgt caagtttcaa taggaggcat
    10381 gtcgtttgta ctttcttata atggaacacc tactcagaaa tatacaatcc gtcatattat
    10441 gagaagacat gcaacgatcg ttggtgttca tataatccgc atacacggat taaggcatag
    10501 tcatgcttct ttgcttatat cacaataaaa agatgcactt cgaattaaag aaaggttaaa
    10561 acatgctgat gtacaaacga ctttaggaac ttatggtcat ttgtatctaa attcattgag
    10621 agagataaca aatgatccca cagattatat ccaaactaat ttttctaaaa tcaaaccgac
    10681 acctatttac gataataaaa aataaatgat aaacaaaagt aggatcacac caaaagaaac
    10741 acactagaaa aactataata caggcttttc tagcgtgttg tttcttattt ccgcctattt
    10801 atacattata ctcataaagc atttaatgca tcgatcgtag ccgcattgtc tatatgggta
    10861 tataaagttg ttgtattggt acttgaatgt cccaattgtt gggcagttaa taccaatgaa
    10921 tttgtctgtt ggtagagtct agtagctaat gtatgacgca gtttgtgagg gctgacttga
    10981 attctaaagc cttttgaata ttttgctacc atccgttcga ttgcaatacc ggatatacgc
    11041 ttggcttctc cttggtaaat tgctagaaat aaagcttttt cgttttctgt tactttatat
    11101 cgttctttcc gaatagctag ataattagct aaatattcca ttgcgaatgc tgctatattg
    11161 acagcatctc ttttatttcc ttttctagtt actaccacat tattcttatc taaagatagg
    11221 tcatctaaat taatatttat aacctcggag agtctcaatc cagatcctaa aatcagtgca
    11281 ttgatcgcca ggtctctttc tacatctcgt tgataataga tcaaagctcg tttactcaaa
    11341 gtatttttat attcattggc aatataatct agataatttt gtgtatcctt atctagaaat
    11401 aattttttct caatggcatt ggcacgtgca gctaacgtag ttttatctgt gatggttgct
    11461 acttgatcca taggattatt gtctaagtat ggttttccta gaggattatt ggaacttttc
    11521 gaaagatatt taaatagaac ctttaatgcc gtgatatttc tattgatagt agaagtagat
    11581 agacctaagt tattattatc tttgagctta gtttttgttg tctctttttt tacattttct
    11641 tttgtgcgac gtttcaaatg agatttgtac aagtttaggt cataggcagt taactgtctt
    11701 atcgaggtga tagaagtatc aggaacgata gactcactca gaagccattc ataaaagagc
    11761 ttataatttt ttagatattc taaagtggtt cgaggtgatt gatctttatc ctcacgatct
    11821 tgaacaaaat cttttatata atcgggcata tgaagtatga ttgtatctat tttttgatat
    11881 atttctgtat ttttcatgtc attcatcctt tcaataagta ggggagaaga gtatctctat
    11941 aattggacta taccaattat agaatgtttt gtcaattggt atgctctaaa atttattaat
    12001 ttgtttcaaa aaa
//
LOCUS       DADVXB010000082        12001 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.084, whole genome shotgun sequence.
ACCESSION   DADVXB010000082 DADVXB010000000
VERSION     DADVXB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.084"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            28..2046
                     /locus_tag="KB902_001795"
     CDS             28..2046
                     /locus_tag="KB902_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6808619.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    2116..2322
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2473..4887
                     /locus_tag="KB902_001796"
     CDS             2473..4887
                     /locus_tag="KB902_001796"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBB6808620.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            5235..6788
                     /locus_tag="KB902_001797"
     CDS             5235..6788
                     /locus_tag="KB902_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6808621.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(7169..8953)
                     /locus_tag="KB902_001798"
     CDS             complement(7169..8953)
                     /locus_tag="KB902_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808622.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8968..10689)
                     /locus_tag="KB902_001799"
     CDS             complement(8968..10689)
                     /locus_tag="KB902_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808623.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            10789..11550
                     /locus_tag="KB902_001800"
     CDS             10789..11550
                     /locus_tag="KB902_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6808624.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         3931 a         2171 c         2432 g         3467 t
ORIGIN      
        1 agataaattg aagttggagg atagaagatg gaaaacattg caagaaaaga acggagacgt
       61 ttagaacaga ccaaacgttt tcgaaaagca aaacgagggg cagcaatcgt gggaactgcg
      121 atggtaggct gttctgtcgc tgccccatta gtacagccgg ttcctgttca agcggatgaa
      181 acacctgttc agttcggcgc aagaatcaat acagcggcat ttatcacaga aattgctact
      241 tatgctcaac caatcgctca agccaacgat ctatatgcat cagtgatgat cgcacaagca
      301 gttgtagaaa gcggttgggg cagtagtgcg ttatctcaag caccttatta taatcttttt
      361 gggataaaag gcagctatca aggacaaacc gtctacatgg atacgcttga atttttaaat
      421 aatcaatggg taaataaaaa ggagcctttc cgacaatatc cttcttttgc tgaatctttc
      481 aatgacaatg cctatgtact tagaaatact tcatttggca acggttatta ctatgccggt
      541 acttggaaga gcaacacgaa atcctataca gatgcgacag cttgtttgac agggcgttat
      601 gcgactgatc ctggttacgc aggcaaatta aataatatca tcgcaactta cggattgacc
      661 caatatgata caccagctag cggaaacgca ggcggtggag cgactacagg tggcaataat
      721 actggaagtg caggtagtac tggcggttca agcaattctg gtaatacaaa ctcaggttca
      781 gcaacttcga ccacttatac tgtccaatct ggtgattctg tttggggaat ctcaaataaa
      841 ttcggtatca caatggatca attgatccaa tggaacaaca tccaaaacaa tttcatttat
      901 ccaggacaaa aactgacaat caaaggtagc caggaaaatg gctcttcgac gaataattcc
      961 ggtaacaata ccaactcttc aggaaatgct ggtacatcaa acggaggaca aacaactggt
     1021 gcgaaataca ctgttcaatc tggtgattct gtttggaaga tctcaaatga tcacggaatt
     1081 acgatggctc aattgattga atggaacaat atcaagaaca atttcgttta tccaggacaa
     1141 cagctaatcg tatcaaatgg cggttcttct aatgctggag caaatactgg ctcaaatact
     1201 gggaatacaa gtggctctag ttcgtccagc tcaagttctt ctaatacagc ttcaggaacg
     1261 aaatatacag ttaaagccgg agactctgtt tggagcgtct caaataaata cggaattacg
     1321 atggctcagc taatccaatg gaacaatatc caaaataact ttatctaccc aggacaacaa
     1381 ctgactgttt caaacagtgg atcaacaaac agcacgtcag gtaatacagg ttcgtcaacc
     1441 aatacaaata acagcagttc agttaatact ggcagcagtt cgtctcaagg cacttatacc
     1501 gtgaaagcag gtgaatctgt ttggagcgtg gcaaataaaa acggcatcac gatggatcag
     1561 ttaatcgaat ggaataatat caaaaacaac ttcatttatc caggacagca attgatcgtt
     1621 aaaggtggaa cttcggcaaa tacaaataca ggttcaacta cttctgcagc gaaaccaaat
     1681 acaccgaata cgtctgctac gacaagtaca tcatccactg gtaatacgat gtataccgtg
     1741 aaagcgggcg agtcagtttg gagcgtagcg aacaaacatc atatcacgat ggatcagtta
     1801 atcgaatgga ataatatcaa aaataatttc atctatccag gacagcaagt gattgtgaag
     1861 aaaggttcat ctcaatcaac aaaccaacaa tcagttactg gttcgaaaac ctatactgtg
     1921 aaatctggag aatctgtttg gagtgttgct gacagtcatg gaattacaat ggctcaacta
     1981 atcgaatgga acaatattaa gaacaacttt atttatccag gtcaaacgtt gattgtagct
     2041 aaataaaata gctgttcgaa gaaataacga ttgaattcca caaaaatatt tgttactata
     2101 aggctactta aatatgacaa cacttgaaaa ggaagtagta aaaagactga agtttcagag
     2161 agcgcatggc tggtgagaat gtgcacggat gcttttgaac tcgcctttga gttgcccttg
     2221 ctgaataccc gagtaagcaa gcggcggtga cggccgttac aacgttcgag gccttttcac
     2281 taaggtaaaa ttaggtggta ccgcgtagat tacgtcctat aaaaagagca atctttttat
     2341 aggatttttt tatttctttt gtgaagtttg agaaaacaaa gcaaaaggaa ataaaaataa
     2401 acagattctg ccggtttttt cgttatattt ataatagaaa caagtgtttt caatagaaca
     2461 ggaggacagc aaatgagtta caatcataaa gaaattgaga aaaaatggca aaaatactgg
     2521 gcaaaaacga atactttcaa cacccatgat gatcctgaaa agccaaaatt ttacgcactg
     2581 gatatgtttc cctatccatc cggtcaaggg ctacatgtag ggcatcctga aggttatacg
     2641 gcaacggata tcctttcacg tgtgaaaaga agtcaaggat acaacgtgct gcatccaatg
     2701 gggtgggatg cattcggtct gcctgctgaa caatatgcgc tagatacagg aaacgatcca
     2761 gctgagttta cccaaaaaaa tatcgaaaca ttccgacgcc aaatcaattc tttaggattt
     2821 agttatgact ggaatcgcga agtgaataca actgatccgg agtattataa atggacacaa
     2881 tggatcttta cgaagcttta tgaaaaaggt ctagcttatg aagcagaagt agcggtaaac
     2941 tgggtacctg aattaggaac agttatttca aatgaagaag tgatcgatgg gaaaagtgaa
     3001 cgtggtggct atgatgtagt cagaaaacca atgcgccaat ggatgctgaa aatcactgct
     3061 tatgctgatc gcttattgga tgatctagaa ttagttgatt ggccagaaag cattaaagaa
     3121 atgcaaagaa attggatcgg tcgttcagta ggagcaaata ttgaatttaa agtggctggt
     3181 acggataaat cctataccgt atttacgaca cgaccagata ctctattcgg tgcaacttac
     3241 tcggttcttg cacctgaact agatcttgtt agagaaatta cgacccctga acaaaaagct
     3301 gctgtagaag cttatatcga agagacagct aaaaaatcag atctaaagag aacggatctt
     3361 gcaaaagaaa aaacaggagt atttactggt gcttatgcaa tcaatccagt taatggcaag
     3421 gaaatcccaa tctggatcgc cgattatgta ttatcttcat acggcacagg agccatcatg
     3481 gctgttccag cacatgatga acgtgacttt gaattcgctc aaactttcgg actagaaatt
     3541 cttccagtta tcgaaggtgg agatgttgaa aaagctgctt acacagaaga tggtacgcac
     3601 atcaactctg aatttctaga cggcatgaac aaacaagaag caatcgataa aatgaatgaa
     3661 tggctagaag aaaatggcgt agggaaaaaa gaagtcagct atcgcttacg tgactggcta
     3721 ttctcccgtc aacgttactg gggtgaacca atcccaatca tccattggga ggacggaaca
     3781 gtcacagctg tcccagaaga agagctacca ttacggttgc ctaagacaaa aaacatcaag
     3841 ccaagcggta ctggagaatc tccattagca aatatcgagg agtgggtcaa tgtcgttgat
     3901 cctgtaacag gtaaaaaagg ccgtcgcgaa acgaatacaa tgccacaatg ggcaggaagc
     3961 tcatggtatt acctgcgtta tatcgaccct cataacaaaa aagaactagc agattatgaa
     4021 aagttgaagc gttggctacc agttgacatc tacattggtg gagcagaaca tgcggtactt
     4081 catttactat atgcacgatt ctggcataaa ttcttatacg atatcggtgt tgttcctaca
     4141 aaagaaccat tccaaaaact atacaatcaa ggaatgatct taggcgaaaa caacgaaaaa
     4201 atgtcaaaat ctcgtggtaa tgtagtcaat cctgatgatg tggtcgaaac ttacggtgca
     4261 gatacactgc gcatgtacga aatgttcatg gggccattag atgcttcgat tgcttggagc
     4321 gaaaatggct tagaaggaag ccgtaaattc ttggatcgtg tatggcgttt gatcgttgat
     4381 gagaacaata aaatgcgtga ccgtatcact acattgaatg atggcaagct tgataaagtg
     4441 tatcatcaaa cagtgaaaaa agtgacagaa gactatgaaa atcttcattt caatacagca
     4501 atctcccaat tgatggtctt tatcaatgaa gcctataaag tggacgctct gccttatgaa
     4561 tatatcgaag gatttgttca actactcgca ccgattgctc ctcacatggg tgaagaacta
     4621 tgggcaatcc ttggaaatga tggtggtatt tcttacgcac catggccaac atacgatgaa
     4681 gcagcacttg ttgaagacga agtagaagtt gttttccaag taaacggtaa agttcgtgcg
     4741 aaaagcaatg ttccccgaga cttaggaaaa gatgagctag aaaaagcagc attagccaat
     4801 gaaatagtgc aagaatatat tgaaggcaaa acagtcagaa aagttattgc ggtaccaaac
     4861 aagttagtca atatcgttgc taattaattg gctctttgtc aataaggact gatgagttgt
     4921 gcaaaatcaa atctgggcca gaatgaactt cattctgtct cagatttttt gttatttcaa
     4981 attgattaat tgattgatca aaaaggtttt gattttcatg ttctcaaaca cgttcaatgt
     5041 ctttttcttc tgaatggtct tgtaagagat ctctgtaatc atcaaatttt tgtctattaa
     5101 tcttagtatt ttttgatgta taaactacct gaaattgaga gtacatacca aattcataaa
     5161 ttttttatta gtgggactag tgattgtatg gattttgacg cataatgaat gaagtatgag
     5221 aaaaggagag acaaatggat caagaactat ttattatcga agtattatca gctaaacaaa
     5281 aaattatcga gaaagcgaaa aaaagagcga aaagaataat gttcaagctt ttaagcttag
     5341 tatttttctc tggtttgctt tttttcggag ctgtatcgtt cctatatcgc catatgagtg
     5401 cagtagtccg ttcagctgaa gggatgcaaa aattaaataa tttgtatcac ttttcgtggg
     5461 gagttggcgg aataacaatt gttgtgctta ttgtttttct tctacttatt tggctccgtt
     5521 accatcaatt gtcgcgtcat ttcgatcaat ggcttagtca aagagcacaa cagtttttac
     5581 ataataaacc aacttctcaa gatgatgact atctttattt tgagaagact tcgacgagtc
     5641 aagcttttcg gatacaaaaa agtgattgcc agttattgct gagatcactt gatgatttac
     5701 ctatctactt aggcgaaagc aaatcaaaat tcggaatgaa cacattccat atttttttac
     5761 tagaaaacga acccagatgg gaaaaaagcc agtcttcgcc tggtggatac ctgacaacta
     5821 agatgagtac attagtcact ggttttttcc tcattctttt agctggaaca atctattatg
     5881 ggagatacac tcagccaaaa atgtcttctc atataaatgc tgcttctcac atgacaatga
     5941 actcaactaa cgatacgcat atacaaaaga caaatgaagg gttgttagct gatcctaagc
     6001 aaaaggtaaa tttgacaaca caaaagataa atgatctcaa acttgataca gagacgcact
     6061 ctctctatat gacaacagat agtggtgcta attgggtatt tgtgccgatt gattcgcaat
     6121 ggttgcgttt tggcgaatac accctgacaa cggggctgat tcctgaaggt tattggatgg
     6181 acaacacata tgatatttcc gccgatttct catggtttat ctattcttct ggggatgatg
     6241 tacgtctgct gacttcaaga gataatggta aaacatggca aacgtctatt atcacccaat
     6301 cagttcagcc gatacgttat cgaaaagcgg tattttatgg caacgatggt ctatttatct
     6361 gtacatcagc cagtgggatg tctgcagaaa ctttgtacat ttacactact atggatggcg
     6421 gaatcacttg gataaaaagt ggaagtacaa tgatcaatca gccagtacaa aatgtcagct
     6481 tcgttacaac ttctttaggt tttgtttcga cacgtgaaag tttgttttat acaaacaacg
     6541 gaggacgctc attcaaagaa tcagttctgt cgattccgga aaactatcag acagggggga
     6601 tagatctttt tcaatcacca aatgaagtta ctcaaataag cgcgaatacg ttagagacaa
     6661 aattttattt gttgaaaaaa ggaccaatcg atgcagggaa aatgtttgcc tgcctcttcc
     6721 gttcaactga taacggggaa acatggcaat tcgttcagca actatcgcaa gtagaacaag
     6781 gagattaaag aagagagatt gtgagcctga cgttcagcac cgagtcacaa gaaacaaatt
     6841 caaaaaacag cttctcatat ttgttgaata gtgtaactcg tgattcggag ttgacaagag
     6901 caacaagaag cgattttgaa gtatagcttc tcgtatttta caagatcgtg tcttattgcc
     6961 gataggttgt ctcttgaaca ccgtttattc gtaaaaaggg attgtgacaa gtcttttgtc
     7021 actacttacc gaacgaaact gaaggagcta tccaaaaagt atcattagta ttattctttg
     7081 tgtttctagt ggcaccacta gtacatttaa aaaagctatc gatcatggac taatcataca
     7141 tgatcgatag ctttttagat aatgtttgtt acgctatctg aaattgacta ttataaagac
     7201 tggcataaag cgttggtgat tggagtagtt cagaatgtgt tcctttttcg acgatatcgc
     7261 cattcttcat tacaaggatc atgtctgcat tttcaatcgt tgacaaacgg tgtgcaatca
     7321 caaaacttgt cctatctttt gtcacagctt ccattgcttg ctgaatcaat gcttctgttc
     7381 gtgtatctac gctagaagtt gcttcatcta aaataacgac aggaggattc gctagaatga
     7441 ctcgagcaat tgtcaataat tgttgctgtc cttgagataa cgtgccgttt tcgctagaaa
     7501 tgatcgtatc atatccgtct ggcagtgttc gaataaagtg atcacattgt gcgatttcag
     7561 ccgcttcgat aatttgttct cttgtggcat ccattttccc gtaggcgata ttatcagcta
     7621 ccgttccttc aaacagccag gtattttgta aaaccatccc aaaagaacga cgtagttctc
     7681 cacgtgaaag cttggtaata tcaagaccgt cgaattcgat ctttccttta ttcagttcat
     7741 aaaaacgcat cagcagattg actaaagtcg tttttcctgc accagttgga ccaacgatcg
     7801 ctaccgtttg ttttggcttt actgaaaaat cgacttgatt catcaatatt ttatctgatg
     7861 tgtaaccaaa ctgtacattt ttgaaagcta tttttccttt cggttgttct aaaagtcttg
     7921 catctggaag gtctggaatt tcatctgttt catctaatat ctcaaatatc ctatcgattg
     7981 ctgccattgc ggattggatc gagttgatca cataagaagc ggtagaaatt ggttcagaaa
     8041 tctgattgat gtactgaaga taagcttgta agaagccgat cgtcacacca cctgatagaa
     8101 caagcatagc accgaatacc gcacttatga tgaaggcgag ttgattaatg aaacgaatgg
     8161 ccggatagat agcacagttc ataaattgag cacgtttaaa agcgttgtat tgctttttat
     8221 ttacttcgtg tatagcagct tctgcatgag cttgctgatt gaatgttttg accactagat
     8281 taccagctaa gatttcttcc attcgattat ttaaaacacc cagttcatac tgattctgtt
     8341 cagaaatctg tttgtttttg ttcgcaatct tagttgtaac aattgaactg ccaacgatca
     8401 gcaataagac gagcaaagta agcttgcttt cgatataaaa cagcatcaga ccagcagcag
     8461 ctattgttac gacagaagta aaaaattgat tgatacctgt caataacact tgagaaagtt
     8521 gattgagacc ggtagttgtc cgactaatga tgtcacctac ttgatgattg tcaaaaaacg
     8581 acatcggtaa tgttttgaat ttttttgtga tttcttttcg caccctcaat gtgatctttt
     8641 cgcttaacgc tgccattgtc cgttcctgaa taaatgaagt gatgctgctt aagactgaac
     8701 agccgatcag caataagaca gggaacaaca atgcttgttt gatatcactg aaagaaagct
     8761 gtccaatacc tgtttttctt atttctgata agagatcatc gatcccgatt cccatgatca
     8821 agggcatggc tacgactaat aggttcccga ataaactgca tagaaacaat ccgtaaaaat
     8881 atttatgttc aggtttgatc attttccaaa aacgtatcaa agcacgcgtg ttcaacgttt
     8941 ttttcttttc catcgtatcc cttctttcta tattccttgt gattttgcaa actcctgata
     9001 agtttggcaa ttagacagta gttcttcatg agtaccttgt ccaacgattt ttccttcatc
     9061 taaaacaatg atgttatctg cttgttggat tgtactgagg cgttgagcaa caatcacgag
     9121 agttttctcc gacatgtgtt tatgaagggc tgctcttaat gctgcatctg ttttatagtc
     9181 taaagcggag aaactatcat cgaatacata gatctctgct ggtttgatca acgctcgagc
     9241 aatacatatc cgctgtttct ggccccctga ataattagaa ccgccttgag caacaaagct
     9301 gtccaatccg tcaggaaggg tgtccactag ttcttctaat tgagcgatct tgatcgcttt
     9361 agacaactct tctgttgagg catattcatt tcccatctgc aagttgctta aaattgtccc
     9421 gctgaataag aaagccttct gagggacata actgatgtgg gagcggatct gttcttgagt
     9481 catttgagta agaggaatac caccaagggt tacttttcct atcgtagggt cactaagtct
     9541 caagagaagt ttcgccaaac tactttttcc agatccggtc ccgccaacga tcgctgttgt
     9601 ttttccttta ggtattgtga aatcaatatc ttctagaact ggatcagaga tttcagtata
     9661 tttaaatgtg acatgttcaa aagcagctgc atttgtctga tcaaaggttg gttcagctac
     9721 tgttttgatc gtctcttcct caatttcgat ctctgcttgc agtatttctt ctatccgtcg
     9781 taatgaggca aacgatttag ggataatgac caataccata gctgcgatca tcaagtaagc
     9841 aagtgtcagc atagagtatt cgactacagc agtcacgaca ccgatttgta atgctccttc
     9901 tgctacaaga tttccgccaa accacaaaat agaagcataa acgattccca tgagcaaaaa
     9961 agcaattgga gtgacccaag caaatattcg gttcactttg atcatttgat tagcatagtc
    10021 agcaaagctc ttattcgttc gcttttcttc atatgattga ttatcaaagg cacggatcat
    10081 attaatccca gtaaagaatt ctctcaatgt gatggtgatc cgatccattt ttggctggat
    10141 actcaaagat aaaggtgccc ctcgtttcat cagtcgataa acaatccata cataaaaaac
    10201 aacagagatc aatgtaaccc atgttagtaa tagagaataa cgaaacatca tgagaatggt
    10261 gaaaacgcaa ataaccggtg ctggtaagat catttggcaa aataaaacaa tcatttgctg
    10321 gacattatcg acatcattcg tcattcttgt caaaagagat ccagaactaa aacgactgat
    10381 atccttcatt gacagctgtt ggaatttacg gaaatatttc tcccgcgttt ggaatccaaa
    10441 cctagcggaa gccaatgctg aaaagtaact agaggcaact gcagcgattg ttcctagaaa
    10501 cgctacaagc agcatttcaa ctccaatttt ttttataact gaggcttcgc cacttgctat
    10561 acctgtgtcg atcagctttg ctactaattt tggtacacct aatgtaccgg cgatttctaa
    10621 acagatcatc acaaaggtaa ggagagcgag tcctttgttt ttctgtaaga atgtttttaa
    10681 gatagacata ttattcctcc ttttttcctg atacttttcg attctatacc ttcaagtaac
    10741 ttgaaggtca atagaaaaaa gaataaactg aaaaagaggt gagaaaaaat gaaaaaaatg
    10801 tatacgattg gccaagtatc ggaactattt gatttgccaa aatcaacgat ccgctattgg
    10861 gatgaacaag gattaatccg ttcaagtaga caagaagaga atgattatcg attgtttgat
    10921 atcgatgata tttttatgct ttatgatatc gttttttata gaaaattaga tataccgatc
    10981 aaacagatga agaatttata tggaaaaaca ttgacggagt tatatgagac acttgatgaa
    11041 acagaaagaa gaatccataa agaactggtg gtgatgaaac aaaaacaaaa agagataagg
    11101 gagcaaaaaa aacagttgaa attgatgatc gatacaaacg aggaagaatt tcctgtagaa
    11161 gagatccctt ttgactgtat gatctcaacg gagtttgaag atattgtgga aatcaaaaaa
    11221 tttctaccta actattcaag ctttgggatg atgagtatgc cagcttccag ttcacagacg
    11281 atgtatggat tttttatcga ccctagtgaa gtacatttat ttactcaaga cgtgatttgg
    11341 gagaaaaaag atacggctgt ttatcgtcga ttcttattga aatccgagat gaaccatgcg
    11401 gaacgtaata atattttaga aatcagagaa agaatgtatg aaaaaggatg gaaaacagga
    11461 gaagtgatcg gccagtatct attgacgaat acggatgaaa acaatatcag aactgaatat
    11521 tatcatgcat ggatagaaat gaaaaaatag gaaatatgtg tttaagataa ctcgaaaatg
    11581 atggttgttt tggttataaa gaaaaatttt ctggttcgat tacgggttta atgtggggga
    11641 ttattagtcg tggatagata gaattttagt tttttagagg aaatatgtct ttaaaaatgg
    11701 aatggttgca attcttagcg atatatacga tgtaattgtc ctcttaaaaa agtatggaaa
    11761 aataattgta ttgggtgtta tgtataattc atggtgaact gagactaatg agaagaaaaa
    11821 ttcatattgt tatgagtgag attgtatcag atgagaatga taaattaaat aggtgcataa
    11881 aagcattaca cttaaaatac attgttgctt acattattac aatatgttaa taaggcaaaa
    11941 ataaatagat ggattgaata aacatatttt ttaatcaaat agtccctact gtgactttcc
    12001 t
//
LOCUS       DADVXB010000083        11771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.085, whole genome shotgun sequence.
ACCESSION   DADVXB010000083 DADVXB010000000
VERSION     DADVXB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.085"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..132)
                     /locus_tag="KB902_001801"
     CDS             complement(<1..132)
                     /locus_tag="KB902_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6808625.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..841
                     /locus_tag="KB902_001802"
     CDS             542..841
                     /locus_tag="KB902_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808626.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            914..2275
                     /locus_tag="KB902_001803"
     CDS             914..2275
                     /locus_tag="KB902_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6808627.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            2297..2557
                     /locus_tag="KB902_001804"
     CDS             2297..2557
                     /locus_tag="KB902_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808628.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2571..3323
                     /locus_tag="KB902_001805"
     CDS             2571..3323
                     /locus_tag="KB902_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBB6808629.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(3417..4022)
                     /locus_tag="KB902_001806"
     CDS             complement(3417..4022)
                     /locus_tag="KB902_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6808630.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(4075..5049)
                     /locus_tag="KB902_001807"
     CDS             complement(4075..5049)
                     /locus_tag="KB902_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBB6808631.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(5427..6146)
                     /locus_tag="KB902_001808"
     CDS             complement(5427..6146)
                     /locus_tag="KB902_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6808632.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(6273..7544)
                     /gene="celB"
                     /locus_tag="KB902_001809"
     CDS             complement(6273..7544)
                     /gene="celB"
                     /locus_tag="KB902_001809"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6808633.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7697..9094
                     /locus_tag="KB902_001810"
     CDS             7697..9094
                     /locus_tag="KB902_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6808634.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            9175..9615
                     /locus_tag="KB902_001811"
     CDS             9175..9615
                     /locus_tag="KB902_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6808635.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9762..10088
                     /locus_tag="KB902_001812"
     CDS             9762..10088
                     /locus_tag="KB902_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6808636.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            10089..10838
                     /locus_tag="KB902_001813"
     CDS             10089..10838
                     /locus_tag="KB902_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808637.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10918..11373)
                     /locus_tag="KB902_001814"
     CDS             complement(10918..11373)
                     /locus_tag="KB902_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6808638.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT         3757 a         2057 c         2403 g         3554 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaagaaaa
      541 aatgaaaaat cggttaattg tcgcatgtgg aagtggagta gcaacgagtc agacaatcgc
      601 tagtaagatc caaagtatgt tagaagatga cggcatcgca tttcctgtag aagcagttga
      661 ttacaaatcg attcaaaatg agcttctaac tgctggaatc tatgtgtatg tcgcacaacc
      721 tgatgaggaa gtacttgaac aagcaaaaga tttgggtatt gaagtatttc caggaattcc
      781 atttttaact ggaatgggtg tagaacctat ttatgacagt atcaaagagt tagtacagta
      841 aaggaggatt gttggataaa aaagttggtt catagtttta tttactatat ttagaaagaa
      901 agaaggttta tttatggaag ttttccaaac cattatcaat tatgttttga acttaggatc
      961 agccattttt gttcccctga ttattttgat acttggattg ttggcaggga tgaaattaaa
     1021 aaaagcattc atgtctgctt tgactttagg gattgctttt agcggaatgt ctatggtcat
     1081 tggctatatg tctaacgcag taagtccagc atcagaagca ttggctaaaa atacgggaat
     1141 cagtttgcct gcacttgatc ttgggtggac aggtgcagca agcatcacat ggtcgtggag
     1201 ttatgctttt atattttttg cagtaacgat tggggtcaat tttgtactgt tactttttaa
     1261 ttggacgaag acgttaaatg ttgatatgtg gaatgtttgg gggaaagctt taactgctta
     1321 tttagtttat tatgtttccg gtagtttggc tgcaggcttt cttactgcaa tggtccaagt
     1381 tatattggaa ttaaagcttg gtgatatgtt tcaaaaacat atacaagatc tcacagggat
     1441 tccattagta acagtgactc attttatgac atctgccgct gtcttgttgc tgcctttcaa
     1501 tatgatcatg gataaaattc ctgctttaaa taaacgagcg gatacgaatg cattgaagaa
     1561 gaaaattggg atcttctctg aaaactctgt aatgggattc attattggat tggggcttgg
     1621 ctttgctgct gcgtatggcg tttcaggttc tcttaatcta gcgatccaaa cagctacagc
     1681 attaagtttg tttcctatga tctctaaaat gttcatgcaa tctttgtctc ctctagcaga
     1741 cgctatgtca gaatttatga aaaagcggtt taaggatcgt gaagtatata tcggattgga
     1801 ctggccgata ttagctggtc gttcagaaat ttgggttact gctattttac ttgttcctgt
     1861 gtttattggt tatgccatta ttttgccagg aaaccaagta ttgccattag cagggattat
     1921 caactattcg attgcggtcg gcggattact tttaacagga ggaaacttgg ctcgtatgct
     1981 gatcttggga atcatcacta tgcctattta tttgtacggg gccacttacc ttgcgccaat
     2041 actcagtgat ttagcagaaa aaagcggagc agtcgaggga atcaagaaag gacagttgat
     2101 cacatggtca tccatagaag ggccggagtt cagggtttta tttgcggagg catttaatag
     2161 gaatattctc gctattgtag gatgcgtgat ttttctagga ctgtttgttc tactttataa
     2221 atatatgata aaagcgaaag taccgagtga acgttatgct gaactacaaa aatagcattg
     2281 aaatggtggg aaagtaatga aaagagaaga gacagataaa ataaaatgga cagtcgctct
     2341 ttgtggtaca cttctgctat ttctatatgg actctttact cagaatatca tcatcaatct
     2401 attggtcatt tttttcgcac tagtgatcta taaatatgga aatcacgttt tattcagaga
     2461 gtacgatgaa aaaagaaaac ggaaaataga agaatcaatg aaaataaaag aagctaccaa
     2521 agaaatattg agagaaaaaa gttttataaa aagataatgg aggggtcatt atgtcagatg
     2581 gacgtatgtt atttgagaga gaacgacagg acatggcacg tatcgtaaga gtgattttcg
     2641 aaaggaaaaa cacaaatgtc gcaggaggga atttttcctt taaaaccact gatgatcaag
     2701 ggaaagacta catcatcatg acgccgacca tgatgtcaga agcctatcta ggagagattt
     2761 ctcctgcaca ggttctagta gtagaaccaa gaacgcgtag aatcgttgac ggagtcggtc
     2821 atttaactcg tgaaatcaat atgcatgaag cgatgtatga gactaatcca gctatcaaag
     2881 ctgtcctaca tgctcatgcg cctaatgcaa tgttctgggc gactactggg ttgcctatgc
     2941 ctaatttgac agaagccaca gctaaagtaa aagagattcc tgtcatggac tttgagccta
     3001 attgctctga agaacttgct gaattgacaa gcgactatgt aaaaaaacag catctcgaat
     3061 taccgcatat gttgctgctc aactctcatg gcgtattgat caacacaggt ggagaatcag
     3121 gaatcgaagc tatccataaa gcactgcaaa tccttgatac agttgaatgg aatgcagaaa
     3181 ttgcctacaa gcagacgatt tttcaagcat tagggattac tgacggtttt tattcaaaag
     3241 gtgagaaaat cgggggattg gaagagttga aacataaaac ggctatttat aataaatctg
     3301 ttattgcagc tggtggagac taacctatct gacacaaaaa actacgactt tcacaaaatc
     3361 tgatccagat cgatatctgc ttcaggttgt attatgtaag tcgtagttct tttcttttat
     3421 ttagttaaga ggtggtctgt ccattccctc gcttgcttga tttcgtccat cgtcaactga
     3481 tgacctgtta cagttagctg aatagtcaca tttgcttggc gtgtttcgaa ttgatcggcc
     3541 aattctttaa aggaagcagg ggaaacgatt ggatcgttat caccataaga aatccagacg
     3601 gttttatcct ctaatgtgga acggctttga tgaacaccta gagacatcgg atggaaaaac
     3661 aaccctttat ttagctcggt ctcacgctcc aataataaat gagcagcgat gtttgcgcca
     3721 tttgaatagc cgacaagcag ccagtcactt aacggtatca gttctttttc gctgatttct
     3781 ttgatttttt catggagttt atctgtttct ttttccaaac tgtccaggtc gaattgattc
     3841 aatccattac gcttgaaaaa acgattcatc ccatcttctt ggaccgtgcc acgaaaagaa
     3901 agcaatgtac tgtttggtgc aagaaagtga gcgatatcca gtaaagaatg ttcatcgcca
     3961 cctgtgccat gaagtaagat caaatgcttg ccacttgttc ctttttcaaa aatgtaggtc
     4021 attttgttcc ctcttttctg tttctataga tgcaaatgaa gtagcatgaa gagattattc
     4081 acgtttttta tttgcatcac ttgtatcgaa aggacggaca taagcttcaa tggcttcacg
     4141 acgttcttct aagaatggag gaagagatag tttttctcct gctgattctg ctggttcatc
     4201 ttcaaggaat ccaggaccat cagttgctaa ttcaaacagt acgtgatgag cggctaggaa
     4261 gtactcagat tggaaataga aacgatcgac gaaaccagaa tttggcaatt caatcttatt
     4321 gattacttga atccagtatt ccaatgcttc tttgtctgct acacgcaatg ctaagtgatg
     4381 gatatttcca aatccttcga ttgcttttgg caagtctgtc cgatgttcaa taatgatgct
     4441 tgcaccattt cccccttcac cgatttcaaa taagtagaaa tctcctgaat ggtctgtttc
     4501 tttgaatcct aagatttttt caagaatcaa gcggatatgc tctaattgac tgacacggac
     4561 aaagacaggt ccaagtcctg tgatcgcaaa ctctgtcggt acattgctgt ttttccaagg
     4621 aatgccagct gctacacctt gattgttttc gtcagagatc aattgataat actgattatc
     4681 gaaatcttca aattcgatat attttttgcc gaaacgttca ttgattgctg aatgagtaac
     4741 gtcatatttt tcaaaacgtt ccaaccaaaa gtctaatgct gcgtcacttg gcacacggaa
     4801 agaagcacga gagatcgtat ctgttccttt ttttcctttt ggctgatttg gaaaatcaaa
     4861 gaaagtcata tctgttcctg gcgcaccagt atcgtctgta aagtaaagat ggtaagtttc
     4921 gatgtcatct tggttaactg tttttttgat taagcgcatt cctaaaatat ctgtaaaaaa
     4981 gcggtagatt tttgtagcgc tagatgtcat tgctgtgacg tggtgaattc ctctgatttg
     5041 tgtatccatg ataaatttcc tcctgttaac ttacaaaaag taagtagttg atttagacat
     5101 agtatagagg gtgcatctct attttgcaat taatttgtct tctaaagtat caggaaggaa
     5161 tcaagaatgg aaaagaggag ggacggatca ataaaataaa aagacttacg actagctgta
     5221 tcgatttcaa aaaaactagc tttaaaaagc taactttaga atcattacgg gtggtcataa
     5281 gtctttttat gctgagttat tttttcattt ttgagctaat gcttaggata gaatagaatg
     5341 ttgatttcac gatctcttct tgttacttga aactgcttac cactgtcacg atctcttggt
     5401 aaacggcttt ttcacaacct ctttggttaa gttgaacgca catccagcac agaatagttc
     5461 cgaacatcaa atcggtttcg gctggaagaa tattcaatcg gctgtccatc tttgagatag
     5521 acgacttgct gaacttccag tacaggatcg ttttctgcac agttcaaata ttgctgatca
     5581 tattcatcac ttttatctgc agaaatagca cgataagccc ctgcaaaatg gacattcaat
     5641 tcttgatgaa gatgatcata gatagaggct aacaaatgtt ctttttttaa acccggcaca
     5701 agatggactg gcataaaggt atgctctaaa acatatggct cgccatctaa gatccttaac
     5761 cggtgaatat tgtagacagg ttgctcggca tcgatcatca atcgttcttg gatatattga
     5821 ttagggaatt caacatcaaa atgaatgatt tgactcttca aagaacgatg tctgcgtttc
     5881 atttggagac tcaaaccttc atactcgtta gcgggcgatg tgtctttttg cataaatgga
     5941 tgattcaaga ttttcgttcc tgatcctcgc tgcgaataga caagtccttc cattgctaag
     6001 atattgatgg cttttttgat tgtcatccgg ctcgcaccaa attcttttac caagtcgact
     6061 tgattaggca aaaaactatc gagaggatac tcttttgaac ggatacgttc tcttaaaata
     6121 tttgcgattt cttcgtattt tggcacgtta ttcacctctt ctagagtata acgaaagatt
     6181 atgcttccga caactcgaag tagcatctgg aacattgttt attcgaaaaa agaggtcatg
     6241 acaagttttt gtcacaaccc cttaatgatc tattaagcaa tatctaaatc tggttgttta
     6301 tctagtactt tcaggaatgg gtaccagata aaggcaacga tgacaaagtc gatgacttgc
     6361 agcataccac caagccatga atttgttgct aagacaccgc ttgcaatgat tggcacagtc
     6421 catggaacag agacgccagt tggtgcaggg acaagtccag cagccattac caaataattg
     6481 aacgtcgtta cgattagagg tgccacaacc caaggaataa ggattgttgc attcaatacg
     6541 atcggtagac cgaagatcgc tggttcattt acattgaaaa taccaggtgc taaagctaat
     6601 cgtccaacat cacgatactg tttcttttta agaacaaagg ccatcaataa aacgacagct
     6661 aaagtcattc cagagccacc aataccaaca gtgaaggttt ccatgaatgg ttttgtgatg
     6721 atgtgtggta attcttttcc atgttgataa gcttctaagt tatcaagcat cagtgtattc
     6781 caaatcgggt ccattacaga gttgacgatg atttgtccgt gaagtccgaa gaaccataag
     6841 aattggacaa agaacaaagc aatcaatgtt gcaggtaaac tacttcccaa accagttaat
     6901 ggtttttgga tcacttcata aacgacgtca tgtaagttag cattgaaaat accagtcatc
     6961 acagcattga ttactaagaa aatagttagt gtcactacag cagggatcaa agcggcaaat
     7021 gattttgtta ctgcaggcgg aactccatca ggcattttga tctgccagcc gcgtttcgtg
     7081 attctgcagt agatttctcc agccaagaaa gcagcgatca ttccaatgaa cattcctttt
     7141 gcgccaagac gatcaagtga aagcacacca gtcacatctt caccgccagc ggttttcatt
     7201 gcaaaaggcg taagaatcaa gaagctggca aaagacacgg caccaccgaa aataccttca
     7261 acgtcataag attttgataa ataatagccg ataccaaaag taacaaaaac cgacatgatg
     7321 ctcattgttg cattttgccc attaccgaat aaattcgata aagttccctt tgttgcgtca
     7381 ctgaaaaaag gcaagttatt gataacgaca acgatcgaac cgaacatcgt taaagggaag
     7441 gaaagcatga aagcatcccg cagcactgta aggtaacgat tttgccctaa taaattagct
     7501 aagggcatga ttttctcaga aagcttgtcc ataaaaccgt tcatttttat tcacctcaaa
     7561 tttatttgca atcgattaca tacaaagtat aacgccaaaa attttaaatg tctagtcatt
     7621 ttcataaaaa gtattgattt attttttagg gttcgttatg attacggtat caagaaaaaa
     7681 gagaggaagt aaaaaaatga aaacctacac attcccagaa aatttttggt ggggttctgc
     7741 tgctagcgga ccgcaaacag aaggaagagt aagtgatgat ggtaaaggag aaaatatttg
     7801 ggatcattgg tatgaattag agcctgaaaa attcttcgat caagtaggac ctgaaaaaac
     7861 ttcgcaagtt tacacaaaat acaaagaaga tgttcagtta atgaaagaaa ctggccataa
     7921 cacatttcgt acatctatcc aatggagtca tttgattcca gaagggacag gtgaaatcaa
     7981 tcaaaaagct gtttcttttt atcgagatta ttttactgaa ttgctggata atggtattga
     8041 accttttgtg aacctttacc atttcgatat gccactacca ctgcaagaaa aaggcggatg
     8101 gttatcaaga gaaacggtcg acgcttatgt ttcttatgca gcagcgtgct ttgaactgtt
     8161 tggagatctg gtcaaaaaat ggtttactca taatgaacca atcgtacctg tagaaggagg
     8221 ctacttgtat caattccact atccaaatca tatcaatatg aaagaagcgg tccaagtagg
     8281 ctatcatgag aatctagcaa gcgcaaaggt aatcaaagcc taccatgaag gcggacatga
     8341 tggtgagatc ggaatcatct tgaatctgac accaagctat ccgagagatg aaacgaaccc
     8401 agaagatgta aaagcggcga agatcgctga cgcattcttc aaccgatcat tccttgaccc
     8461 tgcagtgaaa ggagagtttc cacaagagtt gatcgaaatt gtcaaagaat tggctataat
     8521 gccagagatc catgaaggag acctagaact catccgtgaa aacacgattg acctgctagg
     8581 aatcaattac tatcagcctc gtcgaatcaa agcaaaagaa actccaatca atcacgaaca
     8641 tagccccatg ccagatgatt attttgataa ttacgacatg cccaataaaa aaatgaatcc
     8701 atatcgtgga tgggaaattt acgaaaaagg aatctatgat attttaacga atacaagaga
     8761 aaactatggt aatatcaaat gctatatttc tgaaaatggg atgggggtcg aaggagaaga
     8821 acgatttgtt aacagcgaag gaattattga agatgattac cggatcgagt ttgttacgga
     8881 tcatttgaaa tacgtccatc aagcaatcca agaaggaacc aattgtgtgg gttaccacat
     8941 gtggacatgt atggacaact ggtcttggac aaatgcttat aagaatcgct atggctttat
     9001 cgctgttgat ttggcacaag acggtaaacg gacgatcaaa aaatcaggtc gctggtttaa
     9061 aacggtctct gaaaaaaacg gatttgatgc ctgatatttt ttgataaaac gttcacaaaa
     9121 tgtttgttct aacactgtaa tcgtgctaca ctaacagtga aggaggcgtt tacaatggta
     9181 gatacttatc gtaatatttt agtagcaatt gatggttctg aaaaggcaga aaaagcattt
     9241 cttgaggcaa tcacgattgc caaacgaaat caggcaacgt tgcacatcct gtatgtcaat
     9301 gaagtaacag gcaattactt tggtgatttt gcatttgtta caacaagcct tcaggaagaa
     9361 ttggatgagg ttgcggaaaa ccagatgaaa gaacatcgaa acttggcaat tgaaaaaggc
     9421 ctgacagata tcgagacata tgttctttac ggttatccaa agacactgat tgctaatttc
     9481 catgaatcga aagaaccaat cgatctgatt gtcatggggg cgacaggtct gaatgcggta
     9541 gaacgtgcac tagtaggttc cactacttcc tatgtagtca accacgcatc atgtaacgtc
     9601 atggttgtaa aataaataat taagggaaca gaaagcaaaa aagcataacg cttcttttgc
     9661 tttctgttcc ttttattttt ttgtaaaaaa ttactttacc tgatgaagta atcatgctat
     9721 tctaattaca acgacagatg gagtaatatg gaggaaagaa aatgatttca agtgatggaa
     9781 tacgcggata caatgatgcg attattttat cgatccttaa caaaaacgat tcttatggat
     9841 atgaaatttc taaaacgatt cgtgagagga caaatgattc ctatgtgatc aaagagacaa
     9901 cactttactc cgtttttgcc cgtttagaaa agaatcaact gattgtttcg tatcctggag
     9961 aagtgactca tggaaaaaag cggacatatt ataaaatcac tgaaataggg cgtaatcttt
    10021 tagaagaaaa aaagcaagag tggctgacga cgaaagacgt agtcgatcaa tttttggagg
    10081 gaaattaaat ggatacaatc cgtaattatt tagacagtct ttttatcgga gtacctcaaa
    10141 gtaccgagat agataagctg aaaactgatt tgttggcaaa tatggaagac cattatcatg
    10201 aattgatggg agaaggaaaa aatgaacagg aggccatcgg tacagtaatt tcgacatttg
    10261 gttcaatcga tgaattatta gaagaactag atgtcgaaaa aaaacatcaa gctgacgaga
    10321 cggaaacaaa cacagcttct atttatttaa gcgaagcaga aaactactgg aaagaataca
    10381 gagcggcaag tctccaagtg gcatcaggtg ttctattcat tagcttatct tttgcaagtt
    10441 ttcttttctt ttgttcagca ggatatgtgt tcatgggtat ttcttgtctg attttcggta
    10501 tagcattagc tgtcggtttt tttattgctt ctggtatgaa aatcacacgt ttaaatcact
    10561 ttttgcacca tcggaaaata cctgaaaaag tattagcaga agcaaaagaa aaagaagaag
    10621 agtatcagcg aagttttggc ttctcactga ttgcaggaat tggattatgt attttttcac
    10681 ttttcccact tttggcttct ttaatgtggt atatggatgg tagtatcggt gcctctatat
    10741 tttttgttac ggtaggaacg ggtgtcttct tgatcattta tggcagtcta gtccgtcatt
    10801 cttatcgtca attcactcaa agcgcttatt actggtgaat gtattcagat ttgtaaaaat
    10861 attctattta tccggcgtag aaaaaaagac tgtgacacgc ttttgtcaca gtctttttta
    10921 tatataataa tttaaaaatt catcatctaa atccgtagaa ttttctagat tgcttaccca
    10981 tgtaaaatcg ttatagacag atttcagttg acttctgcgc cattgtacag ggataaaaag
    11041 acgcatgcta tcttcattga atccgactaa taatttcttt ccgtcagtaa tgatgggacg
    11101 ttgtaacaaa gtaaaatgcg agacgatcag atcgacaagc tctgaggtcg tacattggtc
    11161 gatttggtct ttcaaatttt tataatcaat cgagcgttta gctaatagat cgtcaaatcc
    11221 gttttctgtt aatgacaata aataaaatat ctctttcctt gttaaaggct gtttaggtgt
    11281 gaaaattcgt tctctgtaag gcatttgatg gtctttcagc cagtttgcca tcagatggta
    11341 actatgtgtg cgagaagaat agatcgtaag cataaaaaaa ctccttaaat agtccattaa
    11401 tttgttagat ctgttgggat aaataatagg taaggagctg tgcataagca ttgatcaaaa
    11461 caacccaaac atcattagaa ataactttct aaagtcttaa acttgcgacg agaaacaact
    11521 agactaatag aaaaaatgtc ttagccattt ggcttcctgt ttgttttttt gcttatgctg
    11581 cagctcctcg ggaaagggtt ctaacaattt gaagaaggtt gatgattgat ctagtttaaa
    11641 ttgtgtgaaa tttgaaatct ggtgttttta ctagatgaat cacctaacaa ctatgattat
    11701 aacttataga acttctgttt tgcattcggt tttgttatag ttgttataaa gttttatttt
    11761 attacagaac a
//
LOCUS       DADVXB010000084        11658 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.086, whole genome shotgun sequence.
ACCESSION   DADVXB010000084 DADVXB010000000
VERSION     DADVXB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.086"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            109..312
                     /locus_tag="KB902_001815"
     CDS             109..312
                     /locus_tag="KB902_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6808639.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(413..1075)
                     /locus_tag="KB902_001816"
     CDS             complement(413..1075)
                     /locus_tag="KB902_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808640.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(1088..2590)
                     /locus_tag="KB902_001817"
     CDS             complement(1088..2590)
                     /locus_tag="KB902_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808641.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSIGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3138..4817
                     /locus_tag="KB902_001818"
     CDS             3138..4817
                     /locus_tag="KB902_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6808642.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            4944..5423
                     /locus_tag="KB902_001819"
     CDS             4944..5423
                     /locus_tag="KB902_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBB6808643.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            5642..6322
                     /locus_tag="KB902_001820"
     CDS             5642..6322
                     /locus_tag="KB902_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBB6808644.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            6330..7661
                     /locus_tag="KB902_001821"
     CDS             6330..7661
                     /locus_tag="KB902_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6808645.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            7676..8638
                     /locus_tag="KB902_001822"
     CDS             7676..8638
                     /locus_tag="KB902_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBB6808646.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGL
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            8749..9087
                     /locus_tag="KB902_001823"
     CDS             8749..9087
                     /locus_tag="KB902_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBB6808647.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            9166..9873
                     /locus_tag="KB902_001824"
     CDS             9166..9873
                     /locus_tag="KB902_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBB6808648.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(9976..11457)
                     /locus_tag="KB902_001825"
     CDS             complement(9976..11457)
                     /locus_tag="KB902_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808649.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTTKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3726 a         2014 c         2431 g         3487 t
ORIGIN      
        1 aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga
       61 tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta
      121 aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc
      181 aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac
      241 atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac
      301 gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa tccgaaccat
      361 atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt ttttaaactt
      421 cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt tttgctactt
      481 caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt tcttggaaaa
      541 gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca tccgctacga
      601 ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc tgacctcccg
      661 aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga gccagtcgat
      721 ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt gctgctatga
      781 cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata atcgagacat
      841 catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga tagtatacct
      901 ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt tttccagaac
      961 cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct acatctttat
     1021 aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt aacatcaaat
     1081 tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct atagaagcta
     1141 aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc aattgtgcag
     1201 gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga ttattcgtgg
     1261 ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc atttgtccac
     1321 cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt agctgctgtc
     1381 ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca agaatcatac
     1441 aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct cctaaagata
     1501 gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc agagtaagta
     1561 tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt gccacgttgt
     1621 ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta aatgtatctg
     1681 tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga tcagatagag
     1741 tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca tttgcaaaag
     1801 tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata cctatactgc
     1861 cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg gtatcttcat
     1921 cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt tctgctagag
     1981 tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct tcaccatccg
     2041 tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac acaccactga
     2101 tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca ggttcaccgc
     2161 ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg gcagttattc
     2221 catcttttgc catagctgag gcggaacttt caaaggaata actctttaca ttatctaatt
     2281 cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg cctggatctg
     2341 gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta aatgaagctt
     2401 ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga ttcgctgctt
     2461 cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg gctgtgaaca
     2521 cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat gcacgtttca
     2581 taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca acctatctta
     2641 aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg tatatataaa
     2701 aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt tcaaaccgac
     2761 gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag ggatttttac
     2821 gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt tgtataataa
     2881 tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca aaagatccat
     2941 tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac gcggatgtgc
     3001 tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca tatgcttcat
     3061 tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact tggatgtcat
     3121 aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc gttcgtgaaa
     3181 atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta gattgtgggc
     3241 taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat tttacgtatt
     3301 tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat gcagatgcga
     3361 tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg acagagttga
     3421 cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga tttaaggatt
     3481 tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg agctttttcc
     3541 gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa gaaggtagta
     3601 tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat caaacagatt
     3661 atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt gaatcggcaa
     3721 atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa gtatttgata
     3781 cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat ttgcaacgag
     3841 tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg actggtcaag
     3901 atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta ccaagtgaag
     3961 atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg atcattttag
     4021 aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac ggtacacacc
     4081 gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca agcatcgcga
     4141 tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga acagtgaagt
     4201 tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg caattaatga
     4261 tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt gaattagctg
     4321 ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat attactggac
     4381 gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact acaagtgcag
     4441 aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt ttacgtgatc
     4501 gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt cggcgagaaa
     4561 agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta aaagctagcc
     4621 gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa catttagaaa
     4681 gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta ggccgttact
     4741 tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa gctactcaac
     4801 gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt gctcgtcttg
     4861 ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt tataataaac
     4921 gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt tatttagaag
     4981 aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa tctttcacag
     5041 aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc gtagtgaaag
     5101 gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta gattacaaaa
     5161 aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat tttgtattaa
     5221 tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc gcacatcctg
     5281 attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt gtgtcaagcg
     5341 gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc gtccatccta
     5401 tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc agagacctca
     5461 aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt acaattgctt
     5521 tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt ttttcattga
     5581 tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg aggtgtaaaa
     5641 tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa atggccaacg
     5701 cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg cagaagaagt
     5761 aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag atatgattcc
     5821 tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg attatgcgaa
     5881 cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt ttccattcgg
     5941 cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg gtatcgttca
     6001 gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga tttatcatgc
     6061 aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg atattgatgt
     6121 cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag caaaggctgc
     6181 gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc ctgtcattga
     6241 acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa taatgagcgt
     6301 ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg attttagaat
     6361 atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca aaagaattga
     6421 atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc ggactagttt
     6481 caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa catattgaac
     6541 gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc ggggcggcag
     6601 gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat gccatggaac
     6661 gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc caaaaattag
     6721 cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact gctgagattg
     6781 caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat acatttacag
     6841 tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat atcatgcttg
     6901 tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca gatacgattt
     6961 ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc gtcaaccgcc
     7021 atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg ccaaaccaga
     7081 tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg agtattgcct
     7141 ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt tccgatgact
     7201 tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag cttgtccagc
     7261 gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc catacgattg
     7321 atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta gtagcaccac
     7381 aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc atttctgatg
     7441 tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa caagtgaacc
     7501 tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca cgtgtattgg
     7561 aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac accatcgttt
     7621 ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga gtgaaatgac
     7681 agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta tccacaggca
     7741 tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac tattacggga
     7801 aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc ttcgcttttt
     7861 agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca tcgtgactga
     7921 tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa aactgatcaa
     7981 aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa atacaaaagc
     8041 aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat ctttaaagat
     8101 gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag ggctcttttt
     8161 gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa attatccatt
     8221 tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg ctaaactttc
     8281 cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa taatccttcc
     8341 gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga tcgtttcact
     8401 tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc cttcagggta
     8461 ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta aacgccatca
     8521 tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag aagtagagga
     8581 aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa cagaatgata
     8641 cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt caagatcttc
     8701 tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat gacattacca
     8761 aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt gatttgccca
     8821 gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga cggattagtg
     8881 gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt gattaaagac
     8941 ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa gaacatccgt
     9001 ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc gatgaaactg
     9061 aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca ttcttttcct
     9121 actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta tggttatgga
     9181 atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt tatttccgga
     9241 attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag aagcaaaaac
     9301 aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat aaataatgtc
     9361 ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa taagatgttg
     9421 agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt agcagctcat
     9481 gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat tcgtgcagca
     9541 cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat ggtaggtgta
     9601 ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc tttagcatta
     9661 cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc aatccaaatt
     9721 ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca cgtattattt
     9781 gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct gttgcgcttg
     9841 atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa atcagcgctt
     9901 tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga ataagaggat
     9961 gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt tcatatacag
    10021 ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg tatccagata
    10081 gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca aatcagcatg
    10141 ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca aatggctttg
    10201 aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta actgctcttt
    10261 cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga tttggtttct
    10321 ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt cctgtataaa
    10381 agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac tactgctgga
    10441 ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat aaattggtat
    10501 tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca attgaccgac
    10561 ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct gtttttgtcg
    10621 aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg ctctctctgt
    10681 ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg aataatcatg
    10741 tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg gaaaatatgc
    10801 ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt tttcttgttt
    10861 tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta attcaagtga
    10921 ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa gatagagacg
    10981 gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga tccgtaaatg
    11041 gaattttttt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg agggcgatat
    11101 ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat tgattagtaa
    11161 catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact tagaaaaaac
    11221 agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat gattagaata
    11281 aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc ggatcagttc
    11341 tttggttgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag aacaattatt
    11401 tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa ttagcataaa
    11461 tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt ggaaagtcat
    11521 ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt tatttaattt
    11581 ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa gatattcttg
    11641 tttttaaggc ggaaaaat
//
LOCUS       DADVXB010000085        11567 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.087, whole genome shotgun sequence.
ACCESSION   DADVXB010000085 DADVXB010000000
VERSION     DADVXB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.087"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(48..788)
                     /gene="truA"
                     /locus_tag="KB902_001826"
     CDS             complement(48..788)
                     /gene="truA"
                     /locus_tag="KB902_001826"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6808650.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEVPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(979..1614)
                     /locus_tag="KB902_001827"
     CDS             complement(979..1614)
                     /locus_tag="KB902_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBB6808651.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(1761..3002)
                     /gene="sstT"
                     /locus_tag="KB902_001828"
     CDS             complement(1761..3002)
                     /gene="sstT"
                     /locus_tag="KB902_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBB6808652.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            3200..6229
                     /locus_tag="KB902_001829"
     CDS             3200..6229
                     /locus_tag="KB902_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBB6808653.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGTNLIPLYMGYQYQKIARLKVLHYLSRFAFIFLTA
                     TLACNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFIYY
                     LLAVSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVGAF
                     FYCFIFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRFW
                     YALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVLLIVGGLIL
                     LLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNLF
                     KVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKANEINQ
                     TRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGGG
                     TANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYRR
                     KQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQL
                     STMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKID
                     KPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYSNKYSREQAATLNKEVVAPNNF
                     GAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQEK
                     NLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(6289..6999)
                     /locus_tag="KB902_001830"
     CDS             complement(6289..6999)
                     /locus_tag="KB902_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6808654.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATIATTTTTS
                     TESKPTAASTETADTSTSSESSKATETTQTSTSSSSVEASSSESSEQVEQILWNADKS
                     AQLEAFMATWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSE
                     SGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNET
                     ANNELKNGFNQIVYGQAN"
     gene            complement(7226..7768)
                     /locus_tag="KB902_001831"
     CDS             complement(7226..7768)
                     /locus_tag="KB902_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6808655.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIDNEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNMFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(7773..8000)
                     /locus_tag="KB902_001832"
     CDS             complement(7773..8000)
                     /locus_tag="KB902_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6808656.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(8079..9959)
                     /locus_tag="KB902_001833"
     CDS             complement(8079..9959)
                     /locus_tag="KB902_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6808657.1"
                     /translation="MKFQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYMTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLVALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFAKIDTFVFDKTGTLTKGTTAVSTIKNYTENE
                     GDSLALVARLETLSDHPLGRAVIHYVQEKDIDFQQLAVKDNQTIKGQGITAEIDGHAV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSFVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(10149..10763)
                     /locus_tag="KB902_001834"
     CDS             complement(10149..10763)
                     /locus_tag="KB902_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808658.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMGNELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKIKGIGTQLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            10905..11465
                     /locus_tag="KB902_001835"
     CDS             10905..11465
                     /locus_tag="KB902_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6808659.1"
                     /translation="MKKTDRRVKKTEKALAEALSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT         3622 a         2316 c         1872 g         3757 t
ORIGIN      
        1 gatatttata ctgtgaaaca tgcgtttcat ccattatcaa agtattttta tcgataataa
       61 acttcatcca aaaacagacc ttgtgcaggg acggtttctc ctgcatgttg ccgcactttg
      121 ctttcaaata tttcatcgat tgtttctatc ggcatggcac ctgtgccgat ttctagtaat
      181 gtccccatga taatccgcac cattttatat aagaatccgt ctccgacaaa agtaaaatga
      241 agcatttctc cctttcgttc gatagataat tcatcaatcg tacgcactgt ggattttttt
      301 gattttttca atgcagaaaa accaatgaaa tcatgtgtac ccactaattt ttcgcaagct
      361 gcattcagct tgtccatatc caactcttga gggaaataaa agctgtggtt tcgctcaaat
      421 gctgaaggaa tcacgttgtt ccaaacataa tagctgtatt ttttgcccac cgcattatat
      481 cttgaatgga agcgctcagg cacttcttcg attcttttga tgacaatatc ccgcggaagg
      541 taacgattca taaagtcgat catttctgcc agtccaattt ctgtgtttgt tttaaaattt
      601 gctacttgtc ctcgcgcatg ggtgccagca tctgttcttc ctgatccaat aatttctatc
      661 tcttcatttg tcatctgatg caatactttt tcgatttttc cttgaatggt tttatcgtca
      721 tctccaagtc tttgccatcc tgaatatctt tttccgtcat attcgattgt caacttgatg
      781 tttctcatat tttagtggct cctctgtctt ccatttggtc ttctctctac ctttttaaga
      841 ttgtagcaca aaatatagct ccttgcttct ctaagacaga agctatacaa gaaaactgtg
      901 gaaatatata tttcagaaaa acaaaaaaca gccaccggat gaagtatccg ctgactgttc
      961 aatttgacgg ctcaagtttt actgtttgag atgcaagata ctcaaccagg caatgggcac
     1021 ataattaaag aaaaaactga ttctttggca aaaacctatt ttattcagta atggccaaga
     1081 atttatagaa ggaattcttg ccagtccata aatcgccgca aaaagcaaac tgatcacaga
     1141 cagtccaagg tataagtggc ttacgtccat ttgcccattt tttcgataga tcaagaaaag
     1201 aagaactgga aacaataaaa aaccactgta acctaaacct gatccgatat tatggaccca
     1261 tgtcgagaca ttccacgaag attcatgggt attgatactg aacaaacctg taaagataca
     1321 atcacctata ccatagaacg cgatggctgc tgtaactagg gtagctaata cacgagatgt
     1381 acttacaaat gcagcataca atgcaggcaa tgacaggatg aaaaagatcc ctgaaaccac
     1441 agaccaaata agaaacgctt ttcttacagg actggaaacc tctccaaata cactgatcac
     1501 gctcttcatt tgatctaatt caggataata caatcctaat acgtacggag tcaaaaaatc
     1561 actcagcacg cctaataata aaaagaaaaa accaaattta cgtaaaaaat ccatgatacg
     1621 cctccaataa caattaccta tgcttttaat tgttattata aacgacttta tcttgattta
     1681 acagaaacct ctatttacac gaacatctat ataactcatt aaaaactcga atcattttaa
     1741 aaatactaaa tatctaacgt tcaacgttca cttaatccat ctaaacaatc tttcaatttg
     1801 attttttccc cacttctttt acgcgcgcct agctctccta ttgcagtaaa caacagatca
     1861 cttgacgaat ttaaggcagt ttccattgaa tcctggataa caccgataat aaatccaata
     1921 ccaacgattt gcatcgcgac atcattagag ataccaaaca aactacatgc taatggaatc
     1981 aataacagtg aaccgcccgc aacacctgaa gctccacaag cagctaaagc agacaaaata
     2041 cataaaagga ctttcaaaac aaatggtgct tcaatcccta aagaatgtac agcagtcaac
     2101 gtcatcaagg aaatggtaat cgcggcaccg cccatattga tcgtagcacc taacgggatc
     2161 gatatggaat aagactcttt tgtcaatttc aatctttcag ccaacatcat gtttatcggg
     2221 atatttgcgg cagaacttcg ggtaaagaaa gcgggaagtg cgctttcttt caaacaaaag
     2281 aaaatcaatg gatagggatt ttctttaata aacaaaaacg tgaggaatgg gtacacaact
     2341 aatgcgacaa acagcatcgt accgatcaaa acaagtaaaa gctgcagata ctctgccaat
     2401 ccagcgattc cagtcgtagc aattgattga taaaccaatc ctaaaatccc tatcggagca
     2461 aatgcaataa tcacttgtac gacttgtgac aacgctatag atatctgatc caccaactct
     2521 tttgtcgatt ctgaacgtgc tcgaaaagct agtcccaaca atacagccca gaataaaacg
     2581 ccaaggtaat tcgcatcaat aagagattga acaggatttt gtgtgacatt cgtcaacata
     2641 gtagataaaa cactttccaa actttgcggt gctttttcag atactgtttc ttgtaaagta
     2701 ataggaacag taaaaattga acttacaata actgctacaa gtgcagaaag caatgttccc
     2761 actaaatata agatcaaaat aggcttcacg aatgtcttat tcccaatttt atgcttggca
     2821 attgacgcca tcgtcaagaa aaaaaccaga ataggtgcga ttgccttcaa gcaactgaca
     2881 aacaacgttc ccaatattga aataaatgtc catgtgggga aaaagatacc aaacaatatt
     2941 ccgactaaaa taccaacaac aatacgttga actaacgaca tatccaaaaa cttctctaac
     3001 aaatgaccac cctttcacaa ttttaacaat cattgtatca ttttatgcaa agaaactaaa
     3061 ggtataattt tctaaaaatt ctaacaatac aaacaaccat ttcttgctaa ttttgtactt
     3121 tttctgtcta cacgttgttt tttgagatat tctaagttag gatgttatta atgggcaact
     3181 tatcaggaaa cgttttctta tgtttttgtc caattttttt gtgaggtgtt tattcttgaa
     3241 aaaaataaag aaggagagtt atggcttcct gacaatcttt gtcgcttgta taatgatggt
     3301 tttacagcgt atattgattt cagcagtcac tattcctaca tatgcaacaa accctggtcg
     3361 attctacatc tatacatttt tacaaacttc cgttgttatt ggtacaaatt tgatcccact
     3421 ttacatgggt taccaatatc aaaaaatcgc ccgtttaaaa gttttacatt atttaagtcg
     3481 ttttgccttt atattcctaa cagccacact agcttgcaat atcttttttt acgtacaagc
     3541 tggcagcttg aatattcgtg attattggct tatcctaaca cctatcagtc agaattactt
     3601 tacttatgct gtttcttgta ctttgctttt ttgtagtatt ccttatacag ttggattttt
     3661 aaataaatta tcgaaaacaa caattaaata tctactatta tttttaacaa ttggattagt
     3721 tggctgctct actctattta ataaagaccc gtttgcatta cagaatggac agagtatttt
     3781 atggattttt tatttatttt taatgggtta tggtttgaaa gaatggaact ggaaagaaaa
     3841 ggtccgctat aagcttcctc aagtatttat cagcttgatt gttttattcg gtttgattat
     3901 tttgatgaca caaatttcac tcatcatcag aggaaataca gatacagcgc tgaggttttc
     3961 taaaccatat tctctcttcg caatgtatta tactttctct tcgtttttat ttttagaaat
     4021 gctatctgat aaattaggta taaaaggaag aggaaatttt cttgctgtat ttttgattgt
     4081 cactcaagtt atatgtaatt tccctttagt ttcttatcgc gtatctacat ttatgaaacg
     4141 tgaatttcca aactcaggga aggcatggct gataaatatc gggcagtttt ttatttacta
     4201 tttattagca gtgtccctcc tagttatctt tttattttat atacaaaaaa tccgtttcat
     4261 tcatcgtttc atcgaatact tcgcttttga ttcgattgaa caattaacac aacgttggaa
     4321 aaaaagaatt cattggcttt ttgttcataa aagttatttt ttagttggag cattttttta
     4381 ctgctttatc ttcgtgcaga ttttcgtttt agaaccaaaa gaaggttgga aagaaactat
     4441 ccaggttgcc ttaaaaatat ttactcagcg acaagcaccc atgatcctga caatcatcat
     4501 tattatggga tttttcttct tactattgtt gatttccaat cgtttttggt acgccttgac
     4561 tgctaccttg atcattaact tactgctcac tatttcgaca gtaatcaaaa tggaaatgcg
     4621 ggaagagcct gtctttcctt cagatttaaa aatgctgacc ggattgtcag aactattatc
     4681 gatggttagc ccagtcttat taatcgtggg cggattgatc cttctcctat tattgattac
     4741 tagtattatt gtacaacgta gactacaaaa acagtattcc ttgaagattc attggaaacg
     4801 tcgatttatc agtatcgctg tattattagg atgtttttcg ggtgtctttt tcattaatca
     4861 taaaaattcg ccttctttct tgctgtttaa tttatttaaa gtaaacaaga ctttctttaa
     4921 ccagcaaggc gccgtaaaag ataacggacc agtcattcaa ttcctaaaca atatcgacat
     4981 taaaatcatg gaagaacctg ctggctattc gaaagaaaaa attaatggaa taatgaaaaa
     5041 gtacaacaca aaggcaaatg aaatcaacca aacaagaagt gactggttaa acaatcagac
     5101 gatcgttctc aatttaagtg aaagcttcag tgatcctgca cgtgtcccta atctgacagt
     5161 acctacagac cctattcctt acatcaaaag cattataaca gaaggaacag gaggattgat
     5221 gttatccgtc ggttatggtg gcggaacagc taacatggaa tgggaaggac tgacaggctt
     5281 gagtatcagt aacctgtctg cttcgttagt tacaccttat acccagctag tggagcgtca
     5341 gaaaataagt ccaaatatta ccgatctatt cgatgaaaaa atagccatcc atccttttac
     5401 agctgctctt tatcgcagaa aacaagtgtt tgataaattt ggttttgaca ggttctatta
     5461 tttagacagt ccggataaat taacttatac ggataaaata gaacaaagcc cacgcatatc
     5521 ggatgattca gcatacaaag aaaccttgaa agctttacaa agcaatacag aaacgtcgca
     5581 attcatccaa ttatccacta tgcaaaacca tatgccttat gatgattact atagtgaatt
     5641 gaactacact gctgaaggaa ctgctgtcat tcctaataga agaaaagaat tacaaactta
     5701 tatgcaaggc cttcactata ccgatacagc agtaaaaaaa ttcatccaag aaatcgacaa
     5761 aatcgataaa ccgattacct ttgtttttta tggtgaccat ttacccgcaa tctatagtgg
     5821 gaatgattcg aaaaaatatg gattagaaca gcaccagaca gattatttca tttatagcaa
     5881 caagtatagt cgtgaacaag cagctacgtt aaataaagaa gttgttgctc ctaataactt
     5941 tggtgctatg gctcttgagc atgcgaatat caaagtaact ccttactatg cgttgttgac
     6001 agaagtatct aatcatctac ctgcattaac aattgatcct acagaaagct tgtctaatcg
     6061 ttttaatgga aaacaggtct ttgttacaga ggatagtcaa attatccaag aaaaaaattt
     6121 aactgagaaa caaaaagaaa ttctagaaga ttatcgtctg atacaatatg atcttgttgc
     6181 aggtaaccag tacagtgcaa catgggcgac acaaaaaata aaagactaac aaataaactg
     6241 agcaaggggt tgtgataaaa gacatgtcac aaccccttgt ttatctcatt aatttgcttg
     6301 tccataaacg atttgattaa agccattttt caattcatta ttcgctgtct cgttaaagta
     6361 aagataatta tcgggattcc cctgattttg ttgtgtcacc aatacttttg gctgattttg
     6421 ctgaaacccg aatagataga cgtgcttttt cagatatggt tctgtctctg catcggaata
     6481 gacggctgtg atttgataat ctgcttgacc tgtcccactt tctgaccatt ctgcagaaac
     6541 aggcactcca ccaatagcca tcttccactc cccgttcaaa atagcttgag ggactttaag
     6601 accatataag tccacactca tttgattcgt atagcttttg tattgttgtc ccattgtttg
     6661 gccccatgta gccataaatg cctctaattg cgcggatttg tctgcattcc acagtatttg
     6721 ttcgacttgt tcgctgcttt ctgaagatga agcctctaca gaagaacttg aagtagatgt
     6781 ttgagttgtt tcagtcgctt tggaagactc tgacgaagta gaggtatctg ctgtttccgt
     6841 acttgctgca gttggcttgc tctctgtgct agttgttgta gtagttgcaa ttgttgcttt
     6901 cgctgtttct tttgttgatt cttttttcga ttcattcccg ttggtacaac cagctaacaa
     6961 aaaagctaga ccaattgtta ctaaaatcct ttttttcaat taaaaaactc ctttcgatta
     7021 ctcccacttc tttattctat caaataagca atgtgatttt attgattttt tgtattttct
     7081 catccatctt ttaaaccttt taaaaactaa gaagcacccg ctgatgttgt ctgtaataca
     7141 tcagcgggtg cttcttttat tttaatcttc gtgattttcc aatttacctc acgctttata
     7201 tttgtatttg aagaaacata gacttttagt catcatcgtc ttcctcatcc aaatcttgtc
     7261 ggacagtttt tccttggagt ctttgtactt ggtagatgat ttctttattg aaacttaaaa
     7321 gttcaacgag taattgttgc aagccatatt tttcttcttt ttcagctaac ttgattgccc
     7381 gtgtgataaa catattttgg aaatcaaaat cttttgcaaa gttttccaac attgttgagg
     7441 ctggtaaata tttgttttga ccatgttcgt aaatttttcc ataacgcatg acttcttcta
     7501 aagtagacgg aacgatttca ttatcaatca ctaactcatg agagatttta ttgaaccatc
     7561 tcgcttcttg atcagcatat tctgaaaaaa gggtacttaa ttcttgcgaa gatgtaccca
     7621 aaacatacaa ttgtgcttgg atcaatttca tttcttctaa tttaaaattt gctaatacat
     7681 gccccaccat ggcgccagca gttggtttat gatggtcgat atctgcttgt tttgtttctt
     7741 gagcaaattt ttcttccact atattcactg atttacgcct cttttacttt tgttgattgg
     7801 acttcataac ctaatttttc cacaactgca gctaattgtt cagggtggac ttcatctgga
     7861 tcaaagtttg ctttgatttt gctcgcatta aacaaaactt tcgtattgct taccccaggc
     7921 tgttgagaaa ccgcatgttc gattttttgc atacagcttg gacaagctag tgtatctaat
     7981 tgcataataa tttttttcat cgtagttctt ccttcctttt tcttgatagt cttattctag
     8041 attacagctt ccataaaaaa attgattctt atcaagtttt acgatttttc ttctttgctt
     8101 tcgtgtccaa aatacaataa acgcatcgcg ttaaagataa cgatcaagat actagcttcg
     8161 tgaacgaaca tcccactagc catgtaaata aacccggcaa ataagccgat gagtaaaaat
     8221 aagacgacac caatggcaat cactacattt tcacgggtat ttaaaacagt tttcttagcc
     8281 aagcggtagg catgaacaaa cgatccaaaa ctagattgca tcaagacaac gtcactcgtt
     8341 tcgatagcaa catccgttcc tgatcccata gcaatcccga tatcagccgc agccaaagag
     8401 ggagaatcat tgattccatc tccaataaaa gcaacgcgca atccttgttc ttggtatttt
     8461 ttcacaaatt gaaccttttc gtctggtaat aattcagcat ggacttcatc aatgcctaac
     8521 atatcagcta cataatcagc agtcatctga ttatcacctg tcagcatcac taactgtttt
     8581 gctcctgctt gtttcaactt agctaattgt tcagcgactt ctggtcgaat cacatctgat
     8641 acacctatga tttgagtgat ttttttgtcg attgctacaa taatgactga gctgcctgtt
     8701 tgttgtaatt gatgtaaatc ttgtacttgc tttggtgtaa gagaaagttt gtgagcggca
     8761 atcaatttgg tgttgcccgc acaaactgca tgaccatcaa tctcagctgt gatgccttgt
     8821 cccttgattg tctgattatc tttgactgct aattgttgaa aatcaatgtc tttctcctga
     8881 acataatgga tcacggcgcg ccccagagga tgatcggata acgtttctaa tcgagccact
     8941 aaagctaagc tgtccccttc attctctgta tagttcttga tagtggatac agcagtagtt
     9001 cctttggtca atgtaccggt tttatcaaag acaaaagtat cgattttggc aaaagtatcc
     9061 attgcttcac cgcctttgac taagatgccc cgtttcgctc cattaccgat tcctgctaca
     9121 ttcgaaacag gcgcaccaat gactaaagcg ccaggacaac caagaaccaa aacagtgatt
     9181 gctaaacgaa aatcacgact gatcagacca acaagcaacg caacaagtaa aacggttgga
     9241 gtataatact gagaaaatcg atcaatgaat ttttccgcat gggatttggt atcttgtgct
     9301 tcttctacta attcgataat tttggcaaag gtcgtatcat ctccgacctt agttgcttcg
     9361 atcgtcatat agccatctgc taaaatcgtt ccagagaaga cttcatctcc actgattttg
     9421 acgacttgtc gtgattcacc agtcactgcg gcttcatccg cataaccttt tccgtcaatg
     9481 actcgtccgt ccacaggaat agctccacca gtttttacta agacaatatc gccttcttcc
     9541 acgtcatcga tttccacttc ttcagtcgtt ccatcttctt ggacaacact agcagtcgat
     9601 ggggccatct cggtcaaagc cttgattgat tcccgcgttt tggtcaatgt tttttgttcc
     9661 agatagctac caaacaaaaa caagaatgta acgatagctg actccttgta ttctccgatc
     9721 ataaaggcac caagcacagc aatagtaacg agtaaatcaa ttgagataac tttgactttc
     9781 actgcctgat acgcatggat cataataggt atgaccgcaa taatagaagc tatggctaga
     9841 gcaatgttat agaacaagac aaatccagta aattttccga taaaaccaaa aataatcaac
     9901 acagctgata aggcggtgat atgatttcgg tgctcttgga tccacttttg aaatttcatc
     9961 tttctccctc ttttcctttt cgttcttacg agactaagta tagagactta tccatcataa
    10021 aaaattgacc actatcaagt ttagtcaaaa aggcggtttt cttttggtag aatatactac
    10081 aaaaaatagt tagcaagaag actcactaaa agtgatcttg ccaactattg tcgtttctat
    10141 caaaattttc attgaatgat tttcctgtac agcatacatc ggagatctat ttctttatct
    10201 aagattttta tcttgctaat tttttccttt agtctttcaa atccacgtcg ttcatagaat
    10261 tgatacgtac agccgctatc tgtaaaaagg aatatttctt ttcctttctc tctcttttca
    10321 aattctgtta gcaactgggt gccgatgcct tttattttca aatcaggatt tgcagctaaa
    10381 aaaatgatct ctccatctgg cgaatgcttc tttaaatatg ctgcaagcat ttgttcattt
    10441 gctgtctcgt aagctccttt actttcttta gcaaatatat tttgtaaaaa atcgaatatc
    10501 ttaacatata tttgctgtcc aaaagaacga tgtttctttt tttctccttt tatctccgcc
    10561 agcaaaacac ctgccaactc gtcctctgca tacaaagcaa gaatttgagt tgctcgattc
    10621 aactccatat acaaaaaata tcttccgtaa agattcagca gaagttcatt tcccatatat
    10681 ctctcaaagt tcattccttc aacagcaaaa tagatagctt ttttgtaatc tttcttttcc
    10741 aagggtttaa aagttagttt catcatttcg cctcctcaac ttcaatgatt gtgttatact
    10801 tacattataa tagacacagt gtctactatc tataatcaat catctataag attgtcgatt
    10861 aagcgacagc tttgctttga tatgtcggat aaggagatag gtaaatgaaa aagacagata
    10921 gacgcgtcaa aaaaacagaa aaagctttgg ctgaagcact atccacatta ttagtaaata
    10981 aaaagattca agcaatcact atacgcgaac taacagaaac ggcagatgta catcgttcga
    11041 ctttttatac acattataag gatatctatg atctatatga tcaattagaa agcaactttt
    11101 ttcgggatct aaatgaaatt ctctcttatg atccagccca tagctatgag gaactataca
    11161 ctcgcttgat tgactatgtt tacgcaaata cttttttata tcgcttattt atcctcaacc
    11221 atggtgatat ttcgtttcag aagaaagtta aacaagttat tgaagaaaac tatctgaaca
    11281 tatggctata tgaagacaag aaaacgatta tcacagaaga aatgagattc ttcactacgt
    11341 accacgtcca aggttgtcta tctgttctca atcgatgggt agaaagcaat tacaagtact
    11401 ccaaaaaaga attattagaa ctcttacaga aactgaatga tcacatagag aaaatcatgc
    11461 cttgaataaa aacatactaa gcttagttaa gaagaaccgt aaccttctcg tataacaact
    11521 gaatcttatt tagccaaatt gtttactgaa gattttttaa gtaaaat
//
LOCUS       DADVXB010000086        11557 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.088, whole genome shotgun sequence.
ACCESSION   DADVXB010000086 DADVXB010000000
VERSION     DADVXB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.088"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..115
                     /locus_tag="KB902_001836"
     CDS             <1..115
                     /locus_tag="KB902_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6808660.1"
                     /translation="LKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            112..870
                     /locus_tag="KB902_001837"
     CDS             112..870
                     /locus_tag="KB902_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6808661.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(956..1696)
                     /locus_tag="KB902_001838"
     CDS             complement(956..1696)
                     /locus_tag="KB902_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808662.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            1757..3010
                     /locus_tag="KB902_001839"
     CDS             1757..3010
                     /locus_tag="KB902_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6808663.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLIDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            3295..3558
                     /locus_tag="KB902_001840"
     CDS             3295..3558
                     /locus_tag="KB902_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6808664.1"
                     /translation="MEKQANPYDHKKMLTQQLRELEQDESIHRKAYNQVPPKVEYSLT
                     EEGKSLREILVALSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            3681..4007
                     /locus_tag="KB902_001841"
     CDS             3681..4007
                     /locus_tag="KB902_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6808665.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            4075..4788
                     /locus_tag="KB902_001842"
     CDS             4075..4788
                     /locus_tag="KB902_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6808666.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            5098..5949
                     /locus_tag="KB902_001843"
     CDS             5098..5949
                     /locus_tag="KB902_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6808667.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            6070..7935
                     /locus_tag="KB902_001844"
     CDS             6070..7935
                     /locus_tag="KB902_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6808668.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            7983..9392
                     /locus_tag="KB902_001845"
     CDS             7983..9392
                     /locus_tag="KB902_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBB6808669.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            9500..10201
                     /locus_tag="KB902_001846"
     CDS             9500..10201
                     /locus_tag="KB902_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6808670.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            10360..10839
                     /locus_tag="KB902_001847"
                     /pseudo
     CDS             10360..10839
                     /locus_tag="KB902_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
BASE COUNT         3844 a         1922 c         2437 g         3354 t
ORIGIN      
        1 tttaaaaaat cagccagaaa catttgactg gcgatggctg atacttgttg gagtcattct
       61 tattggctta tttgctggat tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa
      121 acaattgcat taagtaccgt tctagctgga agtctattat tatgtacaca aagtgttttt
      181 gctgagaata agagctcagc cactacagaa ggaacgattt ctgtgaccaa accagatgct
      241 gcaaatcctg aagacgttgt tccagttcct cctgttgatc caaatgatcc tgatactcct
      301 tttacacctg acgaaccaaa tcagggaaca tccggattac tgacgattga ccaagctcca
      361 gatcttgatt ttggaacaat caagttaggt acagcaaaaa cagtatatgc tgcattacaa
      421 agcggaacgg acagtactgg agcacaaaca caagtacaga atttcgtaca agtaacggat
      481 aaaagcggaa attatgccgg ttggaaatta tcagtcaaac gaacagaatt tattggtaca
      541 acatctgata cgaataaact aactggttca aaggtgaaat tcaaaaacgc cgtgattcga
      601 aatagcgcaa ctaatagcag tggaatgcca tctaccgttt ctggaactgg cgctgaagga
      661 atcgaaatcc cagcagatca ggcagtagat ctagtaactg caggagcaaa tgaagggatt
      721 ggcacatgga tttattcatt aggagagaat gtggaacaag ggagacaatc agtggaatta
      781 tttgttcctg tatccaatta tgctgtagac aactacgttt caacattcac atggtcgtta
      841 acagatgctc ctacagaaga ggaagcgtaa aatcatatca acgatttcag ggagtggagc
      901 cgattcaagg cccactccct gaaatctgct atgcttacgt ctcagctctt attcatcaac
      961 tcgaagcagt tttttggaag tcatggaaac gttcctttgt cttttcaaag atctttcgac
     1021 caacgagtaa ggagtcaccg ttgaaaaatt ctaacacata atgagcagaa tcaattttct
     1081 gcaattgcga taagttgata cagtaagatt ttaaaagtaa aaagtaagca tacttttcta
     1141 actctgtctt caattgtttt aaagaagtat tcactaattt atcttctgta gttgttttga
     1201 ccataacttg gtttttcaaa cctttgatac tttcaatata taaaatttcc cgaggataca
     1261 ggacgagact tccacctttt tgatcaataa agattttatc gacatttacg atctgctgtt
     1321 ctttccaatt gatctgttct agcacttgac gaatttgttc agataaattc ctgtcttttc
     1381 tgatatatcc aatcggaagg attttccgat tgatgatctc tactgcaaaa ttcgtataag
     1441 cggtgaaaaa aacaatatta ctatgtgcat tttttttacg tatttgttcg gcgacatcaa
     1501 tacctgtgag tgattgcttc aagtcgatat cgataaagaa aacatcgtga ttatcaatag
     1561 tgcccaactg gatcaactga ttgatttgag agatagaagt gagctgcacg atattctcga
     1621 tatgatgatt gaccaattct ctgatgatcc attcgctgtg aaactggtta tcttctatga
     1681 taaaatactt tttcatatgc aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa
     1741 acaatggagg aataagatgg tcgcaacagt gacactttat ttgaccttta ctttgatttt
     1801 agatttaggt atctatttat tcttttcgaa acaactgcta gtaaaaaaca gctttggttg
     1861 tatagctttg atggtggtga cacttttact tcctatccct aaagtgagct ttccttacct
     1921 agttggctta ttattgatgt ttctttttta ttttactacg aaaaacctgt ttatcagctg
     1981 tttgatcagt aatctttttt ttgctatcac tggactcagc ttttttctgg tttttgatct
     2041 gatagattat ttaggaaaga gacatcttgg aacagcaagt ttttttgcac tacttatcgc
     2101 atttattttc tatctattag taaaaagtat agacaaacag acgagatttc tcaacttgct
     2161 ttttacttat ccaactgaac actattttgg aggtatttgt attttattaa gctggggcgt
     2221 gatttacttg gtattgggaa gtgttcactt ccgctcatct aattatctgc ttctatctct
     2281 tttgtcgata gtcatcagtt ttttttcttt gtttttttcc attatgttga tcagtttcca
     2341 agtaaaagaa agacaacatc aggaatcgct tcaactgtat caaataaatg aagaatatta
     2401 ccatcatcta gaggaattca aacatgatta taaaagtcta ctgttttcat taaaaattac
     2461 tcttcaggaa aataaaaaag aaacgttgga atttttagaa atattagaag atcattctgc
     2521 agctattttt gaaaaaccgc aaatacaaca gctaacaaat attgtatccc cagctgtcag
     2581 gggtgtcttt ttaaaatttc tagaaaaagc agaatcggag aaaatcccga tccaagtagt
     2641 tattcctgtc gaagtgaaaa caatcccgat tgatctggtt gtttttattc gctgtttatc
     2701 tatttttatt tctaacgcat tcgatcatcg tgtagccgat cagagtccga ttacgatcaa
     2761 tctgctggaa gaaaaagagg gatcacgttt tagtatagcg aacaaggcaa atccaacgaa
     2821 tttgacgcta tcggagatgg tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg
     2881 tctatacagt gcgaaaaaaa tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt
     2941 ttcaaaacag aatcactatt tttttgtaga aatgtatctg gcatctagaa agagcaaatc
     3001 agcctactga cttactgtca aaggataagt ttgaggaaag tctacacgga gatagagaca
     3061 acaacacagc atattcaaaa gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct
     3121 tttgctatgt agttaaacaa agtagttgac acttccgcta cttagtatta gtacgaaagt
     3181 atacttcatg atactaagta gataagaagt gaaaagcgga acccacgatc gtcaaaatgc
     3241 taactgcttt gcttacacca gataaaggga agagcaatat cgcttatttt aggcgtggag
     3301 aagcaagcaa atccctacga tcacaaaaaa atgctgaccc agcagttaag agagttagaa
     3361 caagatgaaa gtatccatcg aaaagcctat aaccaagtcc cgcctaaagt agagtactcg
     3421 ctcaccgaag aaggaaaatc attaagagag attctagtag cgttgtctgt ttgggaagaa
     3481 gaacgtatcg aaaaacaaaa agcctcaagg gaagaagaca cgctactgca tacacatggt
     3541 ggctacctaa attattgatt ttctatgaca tttattttaa ataaaagaaa acaggagttt
     3601 ttttaaaagc atcatctatt ttttatgtaa aaaaatggta tgattaatca agtaagaagt
     3661 gattggaaga aggcaagcaa atgaatagta tggaaaaagt caaccagttt agagatgaac
     3721 gtaattggcg acaatttcat aacgaaaaag atttggctat ctctatttct ttggaagcat
     3781 ctgaattgtt agaacttttt caatggaaaa cgccggaaga agtaaaagaa acacaattag
     3841 aacgaatcaa agaagaactg gcagatgtat tgatctattc atacatgatg gcagacaacc
     3901 ttcacctgga tctagatgag atcattgaag aaaaattgat caaaaataat ttgaaatatc
     3961 ctgtagaaaa aagcgcaggt gtacgaaaaa aatacacaga gttgtagaaa tgtgtcattc
     4021 ggctgttgga aagagcaaaa gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa
     4081 aaaaaaggaa aagcaaaaag atggctagtc aatatcctct tgttcctctt gttattagta
     4141 ggactagctt tgattttcaa tgaacagatc aaggattatt ttgtcagaga gacaggagat
     4201 aaatatgcta tagcgaatgt aacaaaagaa gatctgaaaa agaataacga taaagatgtc
     4261 agttttgact ttgatgcggt agaaccaatg acgacagaag gggtcatgag gtcgcaaatg
     4321 agaggaacag atctaccagt gattgctagt atcgcagtcc cttcagtttc aatcaattta
     4381 ccggttttca aaggcttgga taatacgtca ctactttacg gagcaggaac attatctcca
     4441 gatcaagaaa tgggaaaagg aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa
     4501 ttgctgttta caccgctaga aaatttagag atgggtgcca agatctattt gacagattta
     4561 gaaaatgtgt atacatacaa aacatttttt aaagaaaaag ttgctcctac agatacccaa
     4621 ttactgaatg aagtcgaggg aaaagaaatt gtcacactaa ttacttgtgg cgacatggac
     4681 gccgtcacgc gactagttgt acaaggagaa ctggaaagtg ttacatcgat aaaagatgcg
     4741 acagatgata tgagatctgc tttcaatcta gagacaaaaa cattttagga tactgggaca
     4801 taagtcgtta cagattaaaa acagccaaag gatatgaatc gataaggaaa aaccaatttg
     4861 ctgaaaaaaa gagaaacgca aagaggtgca tctctgattt ggttgttttc tagatagact
     4921 tgtgttccag tttttttatt ttttatatga aaaggcttgc ataaataaaa attcgatggt
     4981 atgatgattt tgaataagaa atggattgtt actgtacggc aggcaaaacc agaattcagc
     5041 taagaaacag taggcgaatt ctaggttttt ttatttttct tgagagggcg aagcaaaatg
     5101 aaaattgata aaattttgaa taacaatgtc gtcatttcga aaaatggatt cggggaagaa
     5161 gtcgtttgta tgggaaaagg actagctttt caaaaaaaga ttggggacga gatttcgcca
     5221 gaagcggtcc aaaaagaatt tgttttaaga gattcttttg ctaaaaacca attccagcag
     5281 ctgatggctg atattccggc agaggagatc gaatgggtca aacaagtagt cgaactggct
     5341 gaagataaac taaaagttga attttcgcct aatatttatc tgacattgac cgatcatctt
     5401 cattatgcga tcacacgagc aaaagaaaat atccaactgc ctaatccatt attatttgaa
     5461 acaaaaaaat tttatccgaa agaatatcaa gcagcgaaag aggctctttt gttcgtgaaa
     5521 caaaagacgg gtgtggaact ttctgaggat gaagccggtt ttattgcctt tcattttgtg
     5581 aatagccaac aaggaaacga agacatgcaa gtgacgatga ccgctaccac aatggtaaga
     5641 gatatactga gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga atctttgaat
     5701 tatcagcgta tcattactca tctgcagttt tttgcccagc gttatctcaa aggggaagga
     5761 tctgacgagc aagatgaatt tctctacgca ttagttcaag gaaagtatcc aaaagcgttt
     5821 cattgtgtcg aacggatcaa tgagtatctt cgacaaacgc aaaaacagga aatggggatc
     5881 gcagagcaga tttatttaac gattcatatt caaagagtag taagtgagaa aaaaagcatc
     5941 caatcataag gattgttact gtatggcagg caaaacctgg attgaaaaaa taggttcacg
     6001 aatgtttgtg actgtttttt tcaatctggg tttttatttt ttaaataaaa aagaaagaag
     6061 gaaaaaacaa tggataatca agcagttggt cgtcgtgtat gggaagcggt aggaggacaa
     6121 aagaatgtca aaagtttagt acattgtgct acgcggttgc gattcagatt aaaagatgaa
     6181 tctttagcag atacgcaaaa gttaaaagaa gacccggacg tgatccaagt cgtacaaagt
     6241 ggcggtcagt atcaagtagt gattggcagt aatgtagcag atgtttatca atcgatcgtg
     6301 gatgaggaag gtcttgcagt ttcggaggat ggaaaagaag agtccaaaaa tattttgaat
     6361 cgtctgatcg atattatctc tagtatattt acaccttttc taggggcgat ggcagccgcc
     6421 ggggtattga aaggattctt atcattggca acggtgatgg gctggctgac agctgatagc
     6481 ggtacttatc aaatattgtt tgctgcagca gatggtgtct ttaccttctt acctgtcatg
     6541 cttgctttta cagcagctaa aaagttcaaa gccaaccagt ttttagcagt agcaattgct
     6601 atggcacttg tgtatccagc tatcacagca gttgctggtg cgggagaagc tatcagtttc
     6661 tttgggatcc cagtgattct ttcaccatct ggttatactt cttctgtcat accaatcatt
     6721 ctagccgtat gggttcaaag taaattagag ccattcgtaa aaaaagtgat tccgcaattt
     6781 ctgcaaatga ttttagttcc gcttgtcgtt ttagtagtga tggttccatt aacatttctt
     6841 gctttaggac caatcgggac ggttgccggt aatgctttag gcggtctctt caactcgatt
     6901 tatggattta gtccaatcgt agcaggtcta atcatgggaa gtttatggca agtattcgtg
     6961 atgttcggca tgcattgggg attcgtaccg atcatgtttt tgaatatcga acaatatggg
     7021 tttgatgtat tgatgccaat gcttcttcca gccatcttgg cacaaggtgg ggctgcttta
     7081 gctgtagcat tgcgaacaaa agatacgaaa cttcgagcat tagggatttc ttctacagtg
     7141 acttcgttat ttggaatcac tgaaccaact gtgtatggtg tgacattacc tttgaagaaa
     7201 ccattcattg ccgcttgtat ttctggaggt attggtggag ctattatcgg attttccgga
     7261 gtaaaagctt tctccagcag tttggtcagc ttattgacga ttccgacttt cattaatacg
     7321 gtggatggtg tagagtcaaa tgtgacagta gcagtaatag ctacaggaat tgcttttgtt
     7381 cttgcattcg taggtacatt gattttagga tttgacgaac aaacacaaga caatcaatta
     7441 gaaaacaaac atgcgaatgc aggagaaccg attacttcag cacggcatac cttaaaaagt
     7501 cctttaacgg gtaaagtact gccattgagt gaagtaccag accaagtttt ttcttctggc
     7561 gtgatgggaa aaggtatcgc tattgatcca gaagtaggag aactagttgc acctgcagac
     7621 ggagagatca cgactatttt tccaactgga catgctgtag ggatcacaac gactgacgga
     7681 gcggagattt tgattcatat cgggatggat acagtagaat taaatgggaa tggctttgag
     7741 atcttagtca aacaagggga tctcgtcaaa gcaggagatt tattgattcg ttttgacatc
     7801 gaagcaatta gagcagctgg ctatagcgta atcactccag ttgtcattac gaatactgat
     7861 gcatttgccg atatacttga attagaccaa aaagagatta ttgcaaacga agatgttctg
     7921 gcaattgtaa aataaggagg aaatcaggat gcaatcacgt ttttcagaaa aatttttatg
     7981 gggtggagca actgctgcca aatcaattag aaggggctta tgatcgagac ggaaaaggac
     8041 tatccgttgc agatgctatg cctggaggta agcagcgctt tgcgattatc ggcagtgaag
     8101 aatttgactg gacgattgat caagaaaaat atatttaccc gaatcatcga ggaatcgatc
     8161 attacgatcg tttcaaagaa gatcttgcct tgtttgcgga aatgggattc aaatgttatc
     8221 gtttttcgat tgcctggaca cgaatttttc caaatggaga cgaaggtact cctaacgaag
     8281 cgggattaga attttatgat cagctgattg atgagtgctt aaaatatgat attgaacctg
     8341 tgatcacgat ttctcattac gaaatgcctc ttcatttggc aaaagaatac ggtggctgga
     8401 aaaatcgaaa actgatcgac ttctatgaac gatttgctca gacagtatta gagagataca
     8461 gcagtaaagt caaatattgg atgactttca atgaaatcaa ttcggccttt cactttccag
     8521 ctttaagtca aggattagta aaaagcaatg gagcaggaga gtaccaaaat attttccaag
     8581 catggcataa tcaattcgtt gcaagtagca aagccgtaaa aatcggccac gaattgcgtt
     8641 cggatatcca aatcggctgc atgattatct atgcaacaac ttacagcatc gatgccaatc
     8701 cagtcaatca ggcagcaaca atgatccaaa accaagaatt caattttttc tgcacggatg
     8761 tccaagtacg tggagaatac cctgcataca cagcgcgtac ccataaaaaa tatggagtcg
     8821 atccggaaaa attagagcaa acggaaaaag acttccagtt gctaaaagaa tatccagtgg
     8881 actacatcgg atttagttat tatatgtcta cggcaatcaa tgagactgat ccacaagcag
     8941 caacttcaga agggaacttg ctgggaggag taaaaaatcc gtttcttgag gcaagtgaat
     9001 ggggctggca gatcgatcca gaagggctga gaatcgcatt gaatgaatta tacaatcgtt
     9061 accagaaacc attattcatt gttgaaaacg gtcttggagc cattgatcat atggaagagg
     9121 atggcacgat tattgatgat tatcggatcg attatttacg tcgtcatatc gaagcgatgg
     9181 ctaatgcagt agcagacggt gtagatttga tgggctatac gccttgggga tgtatcgatc
     9241 ttgtcagtgc atcaacagga gaaatgagta aacgttacgg ctttatctat gtggatctag
     9301 acgatgaagg aaatgggaca ctgaatcgat caaagaaaaa atcttttgat tggtataaag
     9361 aagtaattgc ctcaaatggc gtaaacttgt aattaaagca gctgaatgaa aaagaacaca
     9421 cttctcacat gtgatttgtg ttcttttttt attttttatg tgctattctt ttagtaatag
     9481 taaagcaaag ggtgacgtta tgaaaaggac acgtgtacta tacttggaag tcgcagataa
     9541 aattaaagaa gatattttct caggaaaata tccagtcggt tcgatgttgc cgacagaaag
     9601 tgaattagaa gaactgtttc aagtcagcaa aatcactgtc cgaaaggcaa tcgaactgct
     9661 ggcatcagat gaatatgtcg caaagaaaag tggtcgtggg acgacggttc taagcaatcg
     9721 tccttacaat cgattatcca aagcggcaag ctttacgcaa atcttggaga actcccgata
     9781 tgaagtccgg aaagaaacgc tggatttgca attggtccat ataaagaagg aagatccttt
     9841 gttttccttt ttcggtgagc aagctgtttg ttttaagcgc ttatattatt tgaacaatca
     9901 gccttatatt tattttgttc attatcttcc acaagaaatg atgcaattca gcagagaaga
     9961 atttggcaaa gaatctttgt atcgtttgct gacgaaaaaa ggatatacta ttgactcatt
    10021 ttctgatgat ttctcggcag tatttttaac agaagaagaa caaggaattc tgaaaacaga
    10081 cgcacagatc ggcatcaaac ggatacggaa atcgtctacg caaattgggg aaatgattga
    10141 atattcggag gcggtctacc atacggagct gcatccttac catattgatt atgaaacata
    10201 aataaaaaaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
    10261 aaatagcttc tcatattttt cgtttggtta ggcttattac cgcagataca cggctgtttc
    10321 tggattacca tttattctgg ataagggggt gtggcacgat tttcagaagg aatctatgaa
    10381 ccaatcactg tattgatttt agcttcgatg gtaaccccat tcggcttgac gatcgcttat
    10441 ttcttaggga aaatcattcg taaaaatata ctcaatcgtc aagaaatcga tacattgaag
    10501 accgcttttc ctatggggat ctgtcagatc acagagggat gtttccctat cgtattgaac
    10561 gacttggcac gcaatgtcat agcaacggga gtcggtggga cagtaggtgg cggattaagc
    10621 atgttttggg gcgcagatag ccgtattccg gcatcgggaa tgtttgcagt cgctacgatg
    10681 accagaccat gggcattcat tggtgcattg ttagctggtt cttttgtcac aggaataacc
    10741 attttattat tgaaaaaacc agtagatccg aatgcagaaa tcatccaaga agaaaaagag
    10801 gaagaagaca tatcttggga tgatttgaca attagttagg agaggcagaa tggattacaa
    10861 gaaaaaagta caatagatgt accttgagac aggaatggta tgaaagaatc agagttagaa
    10921 agaatcgaat atacagattt tggtttagga gcgatcgaaa ctgtccagag catcggcacc
    10981 ctccttgaaa tgacgatgaa ggaaaaatga gaacctttcg ttgtcgaaag ggtctggtat
    11041 accttatgtc gaaggaaagg aaacaaaaaa actttcctgt actattccaa aaaggaaaga
    11101 aagttattat acagtaaaaa aagaaattat tcttcatgct agagatcagt acacgttcga
    11161 gcccaatatc aaacactagt tccaggcagg cgcaacaggt gcggttatca ctgaattttc
    11221 ttccagcagt gacgattcaa gtgatatttt tacaaatcca gctatttatc gttaacaaaa
    11281 agatttttag gagaagctga tgaacaaaaa tgatcaaatt ttgatcgttt agttcgtcgg
    11341 cttttttatt tagagaaaca tcatttatca gtgaaacata acacgagaac aaaatgattt
    11401 tttcgttaat aaaagaaaca agtatttgtt gtttaaaata atacacgtta ttggcatata
    11461 ggacgaaatc ccagtatctt ctataagtaa gtcatttcat atcgatgaaa acacgttatt
    11521 tatttttgtt ttatctataa aatggctgaa aaatgat
//
LOCUS       DADVXB010000087        11541 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.089, whole genome shotgun sequence.
ACCESSION   DADVXB010000087 DADVXB010000000
VERSION     DADVXB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.089"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            345..551
                     /locus_tag="KB902_001848"
     CDS             345..551
                     /locus_tag="KB902_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBB6808671.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(753..1754)
                     /locus_tag="KB902_001849"
     CDS             complement(753..1754)
                     /locus_tag="KB902_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6808672.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1759..3671)
                     /locus_tag="KB902_001850"
                     /pseudo
     CDS             complement(1759..3671)
                     /locus_tag="KB902_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(3839..4345)
                     /locus_tag="KB902_001851"
     CDS             complement(3839..4345)
                     /locus_tag="KB902_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6808673.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4505..4945
                     /locus_tag="KB902_001852"
     CDS             4505..4945
                     /locus_tag="KB902_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6808674.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4971..6128)
                     /locus_tag="KB902_001853"
     CDS             complement(4971..6128)
                     /locus_tag="KB902_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808675.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6131..6487)
                     /locus_tag="KB902_001854"
     CDS             complement(6131..6487)
                     /locus_tag="KB902_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808676.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6785..7759)
                     /gene="sgrA"
                     /locus_tag="KB902_001855"
     CDS             complement(6785..7759)
                     /gene="sgrA"
                     /locus_tag="KB902_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBB6808677.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7955..8794)
                     /locus_tag="KB902_001856"
     CDS             complement(7955..8794)
                     /locus_tag="KB902_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6808678.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8979..9866
                     /locus_tag="KB902_001857"
     CDS             8979..9866
                     /locus_tag="KB902_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6808679.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10460..11155)
                     /locus_tag="KB902_001858"
     CDS             complement(10460..11155)
                     /locus_tag="KB902_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBB6808680.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(11139..11537)
                     /locus_tag="KB902_001859"
     CDS             complement(11139..11537)
                     /locus_tag="KB902_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6808681.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3436 a         2301 c         1730 g         4074 t
ORIGIN      
        1 ctggcttttg gcctcatttt aggttatcat ttgtaatttt atttcacagt tgatatgatt
       61 gttatgtaaa ataaaaaagt ttaggataca tcgaattttt ggggaaattc ttttgggggt
      121 atcctaaatc ttttctatta tattcccata ttttctatta ttggtctaga cgtatgatgg
      181 taaactttgt acctatctga ttgctgaatc attaattgct tatcattagc catctttgtt
      241 tcaagttcgc tagatgatca ttttattcac atcctaacaa acttgtcaca tttatagatt
      301 cttaatctat ttatcataca attataaaaa aggaggtgct gcttatgaaa gctatccata
      361 tttctttgct ttttttcgct agtgcattga ttttatttgc tattcatctt tgttcccagc
      421 cttatatcaa taacaacgga atattagtgg aaccagcatt cttttgctta ccactcggct
      481 ttttgtccct tcttgcctcc gcaggcttcg gatttgttgc tttttttaaa cgatcaaaac
      541 aacaaatctg acttataaaa tttacgtaaa agagatcgtg acaataatcg tgtgatattc
      601 ccaaatttcg aataaaaggt gccccttgcc atctctaact cctcagtcac aagttacaat
      661 attcataaac catgaaaagc ttgtttattg aaattgctcc ttgtgacttg gagctaagtg
      721 acagattaca acctcttttg catcataaga ctttactcct tgaaaaacat tactaacttt
      781 tgatatgttt cttgcgcttg tttattgctg aaatcaaact gatattcatg gttcaaaaca
      841 gcatttttct ccgcataatc tacttttgtg actttcaccc ccgctttctc aaatacagaa
      901 gttacttctt ccatttgttt cgtaaacgta tttgtatttc catccgttaa gaatgtgttt
      961 tgcgtccaac gatccgcatg tctgaccaag gctaaacttt tgaccttctc tgattgttca
     1021 aagtccttat tatcaaagta agcccatcca catttttcat aaagaaagct agagatttta
     1081 tcacttactt gagtaagtgc agaaggatcc aacagaccag acaaagaaat aaacttcgta
     1141 atctgcttgt tctccaaagt cggatcaaga tgatcagctt ttttaatttc ttcattttga
     1201 agtgctaaca aatattctcc actaatttgt gcacctgccg aatttccacc aatcgaaata
     1261 ttcgaccaat ctgcttgatc ttttatctct tttttagctg cttgaatggc ttcgttcaat
     1321 tggataactg gtgtaggatg ttttgcttcc ggtgatcgtt cataatctat atttacgatg
     1381 atttgctgcg tgtctgaaca tagatattcc aaataatcac gacaatcatt tttatcccct
     1441 cctacatatg cgcctccatg catccagaaa agaatcggta attttttctt ttccactttc
     1501 ggtgtgtaga tatccatatt attatttttg tactttgaag gataggatat ttcttttttt
     1561 atatcgattt gttcgatttt ttgctggaaa tcatctggtc gggcatatac ttgttctttt
     1621 tcacttgtgt caaattgttt tctaacaagc aagctaatcg gctttggtgt gatttgatta
     1681 atcaaaaata cagtgactaa aataactacg atgataactg gtactgcaat cactattcgc
     1741 ttgaaccatt tcattcattt accctctctt tcttcgccaa atccatgtga taatcgtgct
     1801 aacagataaa aatccacctg aataaatgag aagcgaatgt ttcttttctc cagttttcgg
     1861 caacattctt tttttgcatc tgtctttttt tgtactttca ctgtcatctg aatcggttgc
     1921 gtatcatcac ttgattgatc ctctcgaggt tcattctttc ccttattgtc tgcattctct
     1981 gtcggatctt gcttttttgg tggagctact gggatttttt tgtaatagaa aataatagtt
     2041 ggtatcgtct cattaaaaat cccttcagtc ggtccttcaa catttgctaa ttcgtatcct
     2101 tcgaatgtct tttgctctgt catataattt tctccataag ctccgtaaag ctggatttcg
     2161 tcctggtctt tgagtagact tttattgttt tcatccacat actttacgtt tatctgatca
     2221 tggaacacta ctttcaaaaa gtccgttaca tgtttcgtgt aggcagcatg gtcaacttcc
     2281 tgtgcctttc catgccctgc tccttctact aataaaagat ctttataccc tcctgataac
     2341 tcatataatt tttgcgcgtt agacacaggt actacatcat ctgctgttcc atggataatc
     2401 aatttaggca atgaatctga cattccaatc gtaggtagag cagcttttgt atccaaatgc
     2461 atctcctgat caaaatagta ttgtttcaaa aggcccataa ataaatcttc atgctcttga
     2521 tccccaatga tgtctaactg attttttatg gcatccggta gtgcgggggc tactgtctgg
     2581 ctgtacgtaa aacgtagttg ttcatcaatt gatgcaaatc cgcaattttc aataattcct
     2641 ttgacattga caggaatatc tttcgctaat acagacatca tcgtagctgc tcccatcgaa
     2701 ccaccataaa gtaaaatctt ttgagatggc cgctctcgaa cttcttgatt tatccagtaa
     2761 aggacgtcat ctgactcata ttgtccatag gtcacataat cgcctccgct attaccagtc
     2821 gctctggaat caacaaataa taaattatac ccggccttat aaaaatcatt gtattcttct
     2881 gtaacgatcc cgttattcca attccctcga aatccgccat ggatcatgac tgttttatct
     2941 gaaccttgat cgacataata tgcatataca tccatcattt tgccatcttg tttgtttagt
     3001 acagtttgat gaagttgttt tgtatttgga tagaagcctg tgttttctgt aggcgttgtc
     3061 ccatcatctg tacctccaag catcgacatc aacacactgt tttttgcaaa agcgatatcg
     3121 tacaatagat aagtagcaat cagatgtttg ataatctctt tatctacacc ataatcatta
     3181 acagcaagct cagtgactaa taactctatt aattttgact tgatgtcttc tgttggtcca
     3241 ttaagtattt ctgtcatctg tttaccgaag taattcaaat attctttacc attgaaattt
     3301 tcacctttac cgatatcatc attttctgtc ccattctctt tgtcacttac tttagcagaa
     3361 gaggattcgt cgtttgacat ttttgtagct gttgcttctt ctgtttgttg gttatctgtg
     3421 gtagcggtcg tttcttgatc tgtgctagta acagatgtct caaccgttgt ttcagtattt
     3481 gtttctgttt gtgaagtact cgatttcgtt tcatttccag catcagtagt ttctgtggtt
     3541 tctacctccc gagattccga ttcggaagaa atgctctctc catatactgt ccattgcggg
     3601 acgcttgtac ttacagcaaa taagatgacc aacgctccct ttaatacttg ttttgttctc
     3661 aagctattca ctccttttta tgtttctagg agaattatat gtaaacgcaa acatttttta
     3721 tacaaaaaat aaatggttta tcccataaaa atagaacagg attattttct cattttacgt
     3781 aataaagcag aatggataaa ccagtatcca ttctgctttt tttaaacgaa gaaacaactt
     3841 attgctccaa aaatgtcaga aatcgtttat cccaaatttt ctcgtaaaaa gcgattgttt
     3901 cctttgcttt cataaaagga ttatcataag ttgtcgttgc tcctctacac atcataagct
     3961 ggtatcctaa tccatgagca aacttcacag tcgtatctat acaatactct gcttgtgccc
     4021 cacataattc gatcgaatga cagtccaatt cagttaataa aacactcaaa ttagtcttat
     4081 aaaatgaatt cgcatgggtt tttctcacaa aataactgtg ctcaggaata gataattccg
     4141 acaatagctc ccatggtttt gtttgtggca ctaattgagc atcttcgtgt tgaacgaaaa
     4201 taactggttt cccaatcgtt tcgtatgttt tgattctttt attcactaat gctgtcactg
     4261 tttctaattc gtgtatcggc gaagaatcaa aacatacccc tttttgtaaa tcgatcacta
     4321 ctattgcgtc ggctgtgttt gacatacttg tgccttcttt cttttttctt gatttaatag
     4381 tatttcttat ctagctagtt ccattatacg tgacaacatt ttcttatttt acacctctaa
     4441 atggcacttt tcgactattt cttcatgtta ttatttcata aatacttagc tattggagga
     4501 atgtatgatg attaaattgt atacaggttc tggctgctcg tcttcaagac gcgcaaaacg
     4561 ttggcttatc gtccatgata taccgtttat cgaacagaac ttaattcgtc aaccactaac
     4621 caaaaatgaa tttatccact tactaaaatt gacaaacaac ggcgtgaccg aaatgctctc
     4681 tactcattct attagttata aaaatcttgt tcacagaata gatgaactca gtttgagtga
     4741 actatatatt gagattcgta catccccttc tttattgaaa aaaccgatta tctacgacca
     4801 atctgcaaaa cttttgactg gatttagcga agataaaatc aggatgttcc tttctaaaac
     4861 taaaagaaag caagagctca acgaactctt gctttctggt catcttgtcg attttaaaga
     4921 aaataatctt tttgcaatgt cttaattttg gcataaacaa tctgcttttc ttaattaacg
     4981 aaatccaatt tttccaatat ggatctattt ttctcattcc tgatttttat gatttcagct
     5041 ttcagacgcg cccaatcatt ttttgtaggt tgtccattcc agtaaaatat ctgtgtattc
     5101 gtttgatcat atgccttttt gtcgatagga taatcgctaa tgacaatatc aggtaactga
     5161 tcagcggatg cactatattt tattgggcgt tcagtcatag ataatatcct tttctttgcc
     5221 cataattcct gtgttttacc atactttgat tgaatataga atatgacagg ttgttcgtgt
     5281 tttataaaaa tatccctgac taacatacag tattgaaaaa tcaaccgtct gttcttttca
     5341 taataagtat taagctctgg aattctgcga gctaccccac taaaaaactg ttgcatgatt
     5401 ggatacatca ctggaaatat atgctgaaaa tctctgtctt ctgctgattt tccaaaagca
     5461 tccaccttct tttttgtccc aaaaaccctt gaatacaaat ggatcattgc caaattgaca
     5521 tatagataat ttttttctga agttgtaaaa caaatcttga agtttttttc aaaattttct
     5581 acaatagacg attcaatcca gccccaactt tcttgtactt tatctggagt atccaacaaa
     5641 tcttcttcca aataggtgtt cattacacca aacataaaat aaaggtaagc ttgctctgtt
     5701 ggagtgatgt gattcatcga ccagaagttt gcttcaaaaa aaggctctag tatgtaatgc
     5761 gtaaactctt cttttgttat caatggatgc acaaatttgt tcatctcttc tgggacatac
     5821 gtaatcgagt ggccttgttt cattcgttgc aacgaaattc ttagtaggct gatccatttc
     5881 tttctatcta tactacgcgt atatggcgca tgtttcgcaa atttttctaa tagttgacgt
     5941 ttatttttta tacttgataa tatatcagaa tgattttcgt cgaatgactg ccaatacatc
     6001 aagtgaaaaa agtatcggat acggtattct tctccttcta tcggattacc ttttttcaag
     6061 ctgcaagata aatgatagtt tttcaaaata gtattaagtt ctcttaattt tctttgaatc
     6121 gtacgcaaac ttatataatt ttttgactaa gattttctaa ggattgataa gtacctttgt
     6181 aaagtgaatc cagtaaaata taaccaatcg ttccctctaa aagtatagaa taaactttac
     6241 tcagtaaaaa ctgagaagaa aactcgactt ttatcatctt gttttctgaa agaaaagata
     6301 atttatattc tggatacctt tcgcaaaacg attctgcttg ttgaatcacc gaattcatct
     6361 tagccagggt gtagtttaga tctaaagcga tatccttcac cacatataat ttctcgtctc
     6421 tttcataaca atagttcaaa aattgatata cttgcctttc attgatatca ataaattctt
     6481 caaacaaagt acatactcct ttttatctat tatttagact tattccgaca gctacatgaa
     6541 taacgtacaa atagattcgt tactgatttt tcagagatac taccatgcgc agtgtgcatt
     6601 gtcaattatt cttgctctta ttttccattt gtgttcctgt tatttcctgt ttctcaaata
     6661 tgttagtaaa caaaaataga tctggcaaag ctacaacttc gccaggcaat acagcactct
     6721 cgaatgaaat attcactcaa aaatctatcg ttttattcaa ttttagatct gttgctttta
     6781 ttctttattt cactcgatgg aagagagaac gaaaatagct tgctcctaca atcaaaatga
     6841 gtaacacacc catccatgta attagcttgt tcaaggttct actaccagtt tctggtaaat
     6901 cgctttttct attatctgtt tctttcgctt tttcttgatg atcaattcca cgagaaacaa
     6961 aatcaggctg ttttagcaca ctttttaggt tgctccctgc atttctcttt tgttccttag
     7021 ttggtatgat aggtaccaaa tcaagttcat tatttacttt tcctgtgctg ctttcgctgc
     7081 tcgtgcttcc tgtgctactc tcactactca tgcttcctgt gctactttca ctactcgtac
     7141 tctccgtact gctttcgctg ctcgtgcttc ctgtgctact ttcactactc gtactctccg
     7201 tactgctttc gctgctcgtg ttttctgtgc tactttcact gctcgtactc tctgtactgc
     7261 tttcaccgct cgtgttttct gtactgcttt cactacttgt gctatccgta ctgcttggcg
     7321 gtccaacaac tgtccaactg cttggtttca aattctccgt gatcgtcatc tgtccatcat
     7381 aaaaaacaat caaatcaact ttatctttac tcttgatctc atcaatcgat agttctgcag
     7441 aaatcattat tgtatactca ataccagcgg tccattgtac gtcttttaaa taaacttccc
     7501 caataacttt ttctgaactt ccattaccat cccaaccata tgttagaaca gcatgtacat
     7561 cactagcatt cacgcttttg tttggtttga ctggaatagt aatgacttgt tgtgtcatgt
     7621 cataaacaat ccgatcagtt ttcacagtaa atgaaagatt ctcatttgcc cgttcatttg
     7681 cagaagtact gattccaatc attgctgcaa ttatactcag cccaagaata acaaataata
     7741 cggtcgctgt tttcttcatt tctatcactc tccatataat taccttctat ttgataaagg
     7801 aattatataa aatgaaaatg atgagaacac gacagtcagt tgtgaaaatc taacaaaaga
     7861 tgtcgtgtat tcgcttgaat ttgtttactt tttcgtttaa tcaatgacag acttaaaaaa
     7921 gcaagaccga tatcagcctt gctttcttca tcttttattg ataaacagca gtgtatttct
     7981 tcatccgctt tgttttatat gcatagagta acaaaccaac aatcaagact aacaagaata
     8041 atgtagttga tatagatgct tcagccccaa agtttccccc agtaattatt gtattttgcg
     8101 attggatcag agtggagaaa aaaccttgtt cttgcgttcc gctgactggt atacccaaaa
     8161 tagctccttg tgtccaattc caagtaatat gagcaccaat agccgtaaat aaacttcctg
     8221 tactgtagat aagtgcgctg aaaaagcaac ctgctaaaaa gatattgaaa actgccagaa
     8281 atgtcatgtt aggattcaat ccgtgcaaaa gagcaaataa tgcagcagat ccaatcattg
     8341 ctattaacgg accaaatcta agcatctgat gctgaaaaaa gccacggaat aaaagctctt
     8401 ctgatgcccc cactgcaata aataaaataa aactcgttat cagcggcaca atgtttgcgt
     8461 ttcctgaatc taaccgatac gcccccgtca aatataatgg actagtaata agcagaaaca
     8521 ctccaattcc aacaacgaga cctcccgcta aataccccca gtcttttcct cgaacagaaa
     8581 caccataatc ttctattctt tttccttcga ccttactagc aagaaataaa gctagtaaaa
     8641 aaacagctaa atgtccgacc gtaccggcaa ttgctccaat ccattcacta tttccaataa
     8701 acatatccgc aagtgcatta ttgacaagaa ttcctaaaac aaaaccaact aagactatta
     8761 aaacagatcc aatcaaccga ataatcctga tcatctttca tccctccttt atattaagtt
     8821 taacaaccct tttctttctt gtctcgtgaa aactatgtaa atgttctcca tcatagagag
     8881 aatagatttt tacgaactaa gaatatctac agcaacctta cgaaaatgaa agactgtctc
     8941 cctaattctt ctgttagact gtttttaata aggaaaggat gggaaatttt ttgaaaaaac
     9001 aactactaat tatgtgcctt tcagcatgtg caattttact attctcaggt tgtagcaagt
     9061 ccaatgaaac gattgcaacg tttaaaggtg gaacacttac agttcaggat ttttatgata
     9121 acccaaaagt taaatcaaat aatcaaacac tattaaaaaa aatgattgtc ttcaaagcat
     9181 ttgatgatgt atacggaaaa gagatttctt caaaggaagt aacaaaagaa tataatgaac
     9241 aaatcaaaaa actcggtcca aactacaagg aacaattaaa agcagttggc caaacagaag
     9301 agacatataa gaaactcttt aaacagatgc tggctttcca atacggtttg aaagccaatg
     9361 taaaattaac agataaagat ctagacactg cttggaaaga attctatcca gaagttagta
     9421 cacagatcat tctattttcg actaaagaag aagcagataa agcaaaaaaa gaagcaaatg
     9481 aaggagaaaa tttctccaag cttgttcaag cttatggaaa aaataaaaca ttaaaggaaa
     9541 ctgatggaaa aatgaatttt gattcaacca atccagagat tcctactgaa gtaaaaaaag
     9601 cagcatttaa actaaaaaac ggggaagttt ctgatatcat tcctgtaaca gatccaacga
     9661 cttatcagca aagctattat ctagtaaaaa tggtaaaaaa acaggataaa ggttctaata
     9721 aagacaaata caaatctgag ctagaaaaaa ttgctaccga agcaaaaact cttgatacgg
     9781 aattcatgga taaaacaatc cgtaaagtga tgaaaaaaga caatgtaact attaaagatc
     9841 cttatgtaaa aaatatattc aaataaacaa atttgaccca attggggatg tggcaaaatt
     9901 tgagaagtga tttttggaaa ttccttctta tttttgaggc aaaccacttt tgccacaact
     9961 tcatcggggc ctttttttat ttgtaccaaa acaaatcact ggatttgtta caatcatgag
    10021 gatataattt aaaaaagttt tttatttcta tcacatgaat caatgcgcca ttaagtagat
    10081 tctttcatgc ttccctattt tttcacttgc cgtatcgctt caaaaacaac tatcataaac
    10141 tcaaactcga ctgaaaagtt attttaaaaa agactaaaaa tatcccttct ggacttgttc
    10201 ttcttattct gttatactag agaaacacga aagatatttt tatgcgacac ttttcatttg
    10261 tttttatgaa atttattcaa aactggcgta acttcagagt tacaaggatg tattagaggt
    10321 tagggaatac atcgtttaaa tgagaaataa gtaatagtta gtaatagtca cccaaacttt
    10381 aaattaatga atattgaatc gtcagatagc ctcctcgagt tttcgagaag gctatcgttt
    10441 attttatgga gaaattgatt cagaagtaat cagcgacctt ttttagttca ccaatcgttt
    10501 ctgcttggaa agtttgcacc caatcttctt ggaagcccct cactgcttta tcaatcgagg
    10561 gcatctctaa tacttgatct agtagctctt tacctaacgt tatcgcatga gctccagatc
    10621 gaatggctgt agtgacttgt tcacaatttt tgaaactagc tgctaatatt tttgttggtc
    10681 tttgcgtacg ttcgatctca gtccgcaacg aatcaatcac tttcatagca tcaatgcctt
    10741 gattttgcat cctgttataa taaggtgcaa tataatctgc tccattatta atagctaaat
    10801 acccttgtaa ttctgtgtaa atagctgtac cggtaatcaa ataaccttct tttttcaact
    10861 ttttgatcgc ttgaaggcct gcttgattca ccggcacctt gataaacgta tcttttccca
    10921 gttcttctat gataactcga gcatcctcta tcatttcttc ttccgttctt cctattgtct
    10981 gaatatggat aggaatctgt ccgattattt ttttgatttc tttcatatgc gagaagaagt
    11041 ttgacgctcc ttcttttttc agaattgtag gatttgttgt tacgcctgtt aaattcaaaa
    11101 actgttgaca agaataaata ctttttgtat ttgctgtatc aagcatgatt tccatatagc
    11161 tttcccccat tctgatcctc ttgatcgatt ttaatgattg tcccctttct taaatgcggc
    11221 atttccttat cttctacata cattgttcct ggaagttccg gctcatgaga tccatcaaat
    11281 tttatcgtga tatgtcctaa ttcattcaaa ttagtttgga caacatctcc tactgctgtg
    11341 attacataca tttgtttatc aaaacagagc ttcatatcac aagttatttc ttttcttacc
    11401 tgattcaatt caatcttata acaataatct gttaatgttt ccggtgcttc atctccaaat
    11461 aaaatcatta ttttttcttt cctgaatact tctgcttcta taccaacatc tgttacaacc
    11521 gtttcaaaga tcgtcatctc t
//
LOCUS       DADVXB010000088        11524 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.090, whole genome shotgun sequence.
ACCESSION   DADVXB010000088 DADVXB010000000
VERSION     DADVXB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.090"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            165..1805
                     /locus_tag="KB902_001860"
     CDS             165..1805
                     /locus_tag="KB902_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBB6808682.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            1959..3281
                     /locus_tag="KB902_001861"
     CDS             1959..3281
                     /locus_tag="KB902_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBB6808683.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3343..3774)
                     /locus_tag="KB902_001862"
     CDS             complement(3343..3774)
                     /locus_tag="KB902_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808684.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3838..4674)
                     /locus_tag="KB902_001863"
     CDS             complement(3838..4674)
                     /locus_tag="KB902_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6808685.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4864..5166)
                     /locus_tag="KB902_001864"
     CDS             complement(4864..5166)
                     /locus_tag="KB902_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBB6808686.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5192..5623)
                     /gene="ruvX"
                     /locus_tag="KB902_001865"
     CDS             complement(5192..5623)
                     /gene="ruvX"
                     /locus_tag="KB902_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBB6808687.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5620..5886)
                     /locus_tag="KB902_001866"
     CDS             complement(5620..5886)
                     /locus_tag="KB902_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBB6808688.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6140..6865)
                     /locus_tag="KB902_001867"
     CDS             complement(6140..6865)
                     /locus_tag="KB902_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBB6808689.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7231..7301)
                     /locus_tag="KB902_001868"
     tRNA            complement(7231..7301)
                     /locus_tag="KB902_001868"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7267..7269),aa:Gly,seq:ccc)
     gene            7418..8170
                     /locus_tag="KB902_001869"
     CDS             7418..8170
                     /locus_tag="KB902_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6808690.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8186..8665
                     /locus_tag="KB902_001870"
     CDS             8186..8665
                     /locus_tag="KB902_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6808691.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8916..10496)
                     /locus_tag="KB902_001871"
     CDS             complement(8916..10496)
                     /locus_tag="KB902_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBB6808692.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10489..11232)
                     /locus_tag="KB902_001872"
     CDS             complement(10489..11232)
                     /locus_tag="KB902_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808693.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11408..>11524)
                     /locus_tag="KB902_001873"
     CDS             complement(11408..>11524)
                     /locus_tag="KB902_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6808694.1"
                     /translation="SRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
BASE COUNT         3502 a         2302 c         2053 g         3667 t
ORIGIN      
        1 taatcaagca aggattgttg atataaaaag aacaaatacc gctattttga tttcttttga
       61 ctctattact catataaata aaatttatta tacctgctct ttttgactat atcctcatct
      121 gactcctata cttcgtttgt attaaaactt aggaggaatc attcatgctt acagggctaa
      181 acttattaaa taatcctttt ctaaataaag gaacagcttt tacaaaagaa gaacgggcaa
      241 aatacggaat cactggtatg cttccaagta ctgtccaaac attggaacaa caatctgtcc
      301 aagcttacgg tcaatactta agcaaacaga ccgatttgga aaaacgtatc ttcttaatga
      361 atctattcaa tacgaaccgg acattgtttt ataaattgat gggcgaacat ttagttgaat
      421 tcatgcctgt cgtttatgat cctgtcgttg cggattcaat cgaacaatac aacgaaattt
      481 tcttgaaacc acaagatgct gtatttcttt caatcgacga accagaaaat atcaaagcaa
      541 gtttgaaaaa cgcagcagat ggacgcgaca ttcgtttgat cgttgtgaca gatgcagaag
      601 gaatcttagg tatgggtgac tggggtgtga acggtgttga catcgctatc ggtaaattga
      661 tggtctacac tgccgcggct ggtatcaatc ctgcacaagt cttgcctgta tcaatcgacg
      721 ctggtactaa taacgaagaa ttattgaata atccattata cttagggaat cgtcatgctc
      781 gtgtagaagg cgaaacttac tacgaattca ttgatcaatt cgttcaatca gctactgaat
      841 tattcccaga attgttatta cattgggaag attttggacg aggaaatgct gcaacgatct
      901 tagaaaaata cgaagataaa atcactactt tcaatgatga tatccaaggc acaggaatcg
      961 ttgtactagc tggtgtatta ggtggattga atatatcagg tgagcaattg aaagatcaaa
     1021 cgatcttgac atttggtgct ggtactgctg gtgtaggtat cgcaaacatc cttttagatg
     1081 aaatgatccg tcaaggtgta cctgaagaag aagcacgcca acatttctat caagtagata
     1141 aacagggttt attgtttgaa gatacaaaag gattgactcc tggtcaaatc ccattcgctc
     1201 gtaaacgctc agaattcact aatgctgatg aattgacaaa cttagaagca gttgtaaaag
     1261 caatccatcc aacgatcatg atcggtactt ctacccaacc tggagcattc actgaagaaa
     1321 tcgtgaaaga aatggcggct cataccccac gtccaatcat catgcctttg tctaatccaa
     1381 caaaattggc agaagcaaaa gcaaaagatt tgattgaatg gacggacgga aaagctttag
     1441 ttggaacagg tatccctgct gctgatgtgg aatataacgg tgtaacttac caaatcggtc
     1501 aagcaaataa tgcgttgatg tacccaggtt tagggcttgg tttgattgct tcaacagcta
     1561 cacgagtaaa tgctgaaatc atttctcaag ctagtcgagc attaggcgga atcgttgatg
     1621 taacaaaacc aggagcagct atcttgcctc cagtagcaaa aatcactgaa ttctctcaaa
     1681 cgattgctga aactgtcgca aaatcagttg ttgcacaaaa attgaatcgt gaagaaatca
     1741 cggatatcaa agaagctgtt gaatctgcta aatgggttcc tgaatataaa tctttagaag
     1801 attaagattg ttatagtaaa agaacataca gaaactttgt atgacgtcta aaaagaaaaa
     1861 agcgactgcg gcaaaacagc agccagccaa ctactgctct tttgccgctt ctctttggct
     1921 tttttcatac gatacagaat aagaaaggat ctgtaaaaat ggcacaaaaa acaacaaccg
     1981 caactgcagt tgaggaaaag aaaaaagaag ggttttggtc aacaaaaatt accggcgtaa
     2041 gtttgcccct ttatttgatc atggtccttg tcctgatcat tgcaatggct ttaggaaaat
     2101 taccgacgaa tatgattggc ccaatcgctg ttttggtcat tttcggtaat ttatttcatt
     2161 ttatcggaac aaaaatccct atagtcaaaa gttatttagg tggtggctcc gtttttgcga
     2221 tctttgcctc tgccgcgatt gctacatttg ggatcttacc tgagtatgta gtaaaatcca
     2281 cagaaaactt tgtcagcaat atgggctttt tagactttta tattgctgcc ttgattactg
     2341 gtagcatcct tggtatgaac cgtaatctat tgatgaaagc ttctgttcgt tttattcccg
     2401 ttgcacttat ttcaatggtc gtctcctttt ttgccgtagg actcgtaggt atgcttatcg
     2461 gaaatggttt tgcaaattcc gttttatata tctcattgcc cgcaatggct ggtggtgttg
     2521 gagccggagc tgtaccttta tcaacgattt atgcaaatgt tttaggtacg gacgcttctt
     2581 ctatcatttc ccgcctgatt cctgcgacag caatgacaaa tgtcctagct atcattggtg
     2641 cagcgttagt tgctcgtgcg ggacaatcaa tgccaaaatt caacggtaat ggtaaattaa
     2701 tggaaaaagg cgaccttggc gatggaaaac ctagaaatgt aaaaccttcc attccacaat
     2761 taggtgtcgg tttgatggta tcattgactt tcttcatctt aggacaaatc tgtaactatt
     2821 ttgttcctaa agtccatgct tacgcattca tgatcattat cgttgttatc tgtaaaatcg
     2881 caaacctatt accagaatat tacgaagatg cagctatcat gttcaacaac ttgattgtca
     2941 aaaacttgac agcagctgtt cttgccggta tcggtattgc gttattgaat ctaaatgtat
     3001 tggcttctgc tttgacatgg caatttgttg tcttatgttt gacaagtgtt atcgcgattt
     3061 cagtagtttc aggatttgtc ggtcgtttgt ttggtttata tccaatcgaa tcaactatta
     3121 ctgctggctt atgcaacaac tcgatgggtg gtacaggaaa tgtagctgtc ttatctgcag
     3181 ctaatcggat ggaacttatt gcttttgctc aaatgggcaa tcggcttggt ggtgccatcg
     3241 ttttgatcat ctcaggtttc ttgatgcaat tactttctta gtcaaaaaaa atacctgatc
     3301 atcaagtatc ggcttgatga ccaggtattt tttgataaaa atttacagga ttttcaaaaa
     3361 tcttttttgc attttatcgg aatgataacc gatgcgttca taaaatcggt gtgcttctac
     3421 tctgtattct gcagaattaa gtcttattgc tgatattcct cgtcttttcg cttcttctac
     3481 gccagtcatc aaggcctttc cgattcctct tttttcagca tgtttagaca cagcaagtgc
     3541 cataatattg aacatcggat cgctgaaaat cgattcatag gactccgctt gtacatagcc
     3601 agctgctttt ttagaagtag gatcttcata gaccaagaaa aaattttttt ctggctcctt
     3661 caacagtttc ttcatttgtc tcaccgtaac ggttaatggt acatcatatc ctaattgttc
     3721 cgcattgatt tctcgtagtg cttctgcatc tcctaaacgc atttcccgca acatccaaat
     3781 caccagccaa tttttatttt tttaaatgaa tttttttatc acagtatact ccttttttca
     3841 cttaaaaaaa gacttttcag tgattttgac ttgcttgaat ccagatcctt ctaatgtttg
     3901 caagatgacg aaagcattgt aaagattgat caaaagaacc acgatgacaa tcgcttgaaa
     3961 aataaaggtc actttttttg gagacaaaac cctgctaaat cttgctcccc acaaacctcc
     4021 aataacagca gcggggataa cataaaacaa catagataaa tcaaagcgca taaagctact
     4081 tgttaaagca atcgttacca attttgccag ttgagaaaag aaaatcgtag atagagaata
     4141 tagtgttgct tcttttattg gcaatgcaaa catcagcatc aacaaagaaa cattgactgg
     4201 tccaccacca atacctaaaa aactagctaa aaagcccaga acccccccac atataaggta
     4261 ccaagtccat gacgtcaaat gaaattttgg ctgatgatgc ttggtgtaga agaacgcaaa
     4321 aaccaaggtc aataccgtca aaaaaatttg gatcagctgc acatgcttct cgttttcaaa
     4381 taactgtaaa aaaacttcga atacaatgtt gccgactact cctccaacaa cagctccact
     4441 agatacccaa ccgacaatct gccaattcag tgatttcccg cttgatactt gtcgcacagt
     4501 cgaaacaatg gacatcgtga ataccgcaac tgttgagtaa aaagaaatcc ctgcaacaga
     4561 atgggcgccg ataagatcaa gaatcggttt gatcaacacg cctccaccca tcccggaaat
     4621 agcgccaact gtgttcgcca gaacgatcac cacaaaataa atcagaccaa tcatcttgta
     4681 tttcctttct cttgtttata tcttttagcg attgttactc ttttctttta ttatacagta
     4741 aaagaaacaa acgaggcttc gaaagctttt ctacttttta aggaaattta gtgctaaacg
     4801 aaaaaaccgg gctctacttt tcagagagtc cagcttttct tacaccttat cgattctttt
     4861 gttctattct tcttccgcca tgaatgtatt gaatacttct tcgatcatat cccattctgc
     4921 gtctgtttcg atttgttcta actcgccttc tgttccatct tcgttttcga tgtatgcata
     4981 agcttgtaat tctacatctt catcttctga aacaccagct ggatataaaa gaacatagtt
     5041 acgtccaaat tcttcttgtc cgtcaactgt tagcaagatt tcgtataatg tttcatttcc
     5101 ttggtcatcc accaatgtga tgtgttcgtg tccttcgtgt tcgtgggaat ggttatgttc
     5161 tgtcataaga ttacctcttt tctttttatt attaaaataa ttgcttacct gagccgtcta
     5221 aataattttg taaaatcatc acagctgcta atttatcgat gacttttttt cgtttcgctc
     5281 ttgaagtatt tgcctgctct actagcatac gttctgcctg aacagtggtt agtcgttcat
     5341 cttgataatc aaccggcaag gagaatagtt ctttgatctt ctctccatat gacatggaag
     5401 cttctgccct tggtccgatg gaattgttca tattcttagg taatccaact acaaaacggt
     5461 ctacttcgta ctgcgccact aattccttca accgatcaaa accaaactct tcttctgcct
     5521 cattgattcg aatgatttct actccttgag ctgtccagcc aaagggatcg ctcacagcaa
     5581 cgcctactgt cttagaaccg acatccaagc ccattactct cataaattca ctccatgatt
     5641 tgagaggtag tctttgacaa ttacttccat gatttcatcg cgttcgtgac ggcgaatcaa
     5701 atttcgtgca tcacgataac gaggaatgta ggccgggtct ccagaaagca agtagccgac
     5761 aatctgattg attggattgt agcctttttc ttccaaagcc cgataaacaa tcgctaatgt
     5821 ttcgctcact tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt catctgtaaa
     5881 acccatgatt ctacacctct ttcccgcaag gtaattccag cttaccttct acacccttat
     5941 tttactcgaa gaaagggaaa actacaaaca aatattccaa acttctgaat aaattaagaa
     6001 acacgatttg tctgattttt ccttttttct gtggcttttt caaaagccct ctttccataa
     6061 agtatacgct atatttcttt gaaagtatgt ttttacacaa ttttttcata aagttcataa
     6121 aaaattcgaa ttgctgctac taatttttcg ttttcgttgc ttgccctgtc tcataattga
     6181 tggtgtagcc atcttgaaca ttgtagataa agacattgaa ttcaattttt ttgtcttcaa
     6241 tgctttctgc ttccaactgc acacctcttg ctaccagttc atttccctcg aaatgaggag
     6301 tgacacgata gcgtacatga tgatttgttt ccttgatata tgccgcaata tcattttcgt
     6361 gggcaagcat gtacggagca ttcaacgaac gtgtccctgt cattaagttt ttaatgttat
     6421 tattttgacc agtcaactgg aaaccaatca aatggctgcg gttgtataac cattgtccgt
     6481 cacttaattt cttttgtttc caacctgtcg gatcaatata caaaggttct ctcttttcag
     6541 taggaaacaa gtcttttccc aacatcgcat tggcttgtcc tactctgttc aatttgtcta
     6601 tatttgaata gctttcccat gtccctttgg aaagactaag atcctctttt gtaaactccg
     6661 gctgattccc attgatttct atttcttgat gttttccatc atattctggc acatccgcta
     6721 cttgagaagc ttgcggtgtg gaatcaaaaa tggttgtaat ttgttggaag atatctgaat
     6781 ctttttgtgt ggtggaaata ccgagtgccc ctgcaatcac agcagcgacg atccccacga
     6841 tcgccttggt tgtttttttg ctcatttctt tactccttta ctaacagttc cctaaatctt
     6901 aacatatgtt cccctataaa taaatactgg aaagaaatag aaacagtaaa aaaataaaac
     6961 cagtttttag acggcttaag aatacaaaaa aagagacgga ttcatcgtct ctactcaatc
     7021 acaaaacact atttacaagg tatttattat cattcaaaaa atttttctta atactcaaaa
     7081 ctaaacggct tctgtacgac ctcttggtaa acagtgttca aaagcttgca tctgcggtaa
     7141 taagtccaac caagtcaaaa acataagaag cttttttgct tgactattct tattacttga
     7201 tgcagggcag ctttttcaca gcctctttta agcgggtgac gggaatcgaa cccgcgacat
     7261 cagcttggga agctgggatt ttaccactaa actacacccg cgatacaaaa acagtatacg
     7321 cctctttcac tccttcctca agttttttta ttctttacgc ttccgatatg ttttgtagta
     7381 aaataaaact aatcaatcaa ttattggaga agatgctatg acgggaaaag aattagatct
     7441 gttgctggac acttgtttac tcgctgggaa aatcatgatg gaaagcaatg cggagatgta
     7501 tcgggtagaa gatacgatga gtcgaattgc tttagcttct ggaaatttcc gtttggtcag
     7561 ctatgtcact caaaccggtc tctttattgg tcttgatcgt acctcgacca tccgaatgga
     7621 acaaattacc aaccgttcga ttaatttaga aaaagtagta aaagtaaatg atctttcacg
     7681 taaatatgtt gcttcagagc taacattaga agaactttac tgcgaactgc aagcaatcga
     7741 ccgagaccgt tctttctttc ctgtctggtt gcaaatcgtt agcgcggcag tgatcagtgg
     7801 aacaattatg gtgttatttg gcggaaagat gaccgattta cctgtgactt tagtcattgg
     7861 aggattggga tacgcagctt atctatatag tttgaaattt tttagaatca aatttttatc
     7921 ggaattttta tcttctttat tgattggcat agccgctatc tacagcgtac gttttggctt
     7981 aggaagcaat caggatctaa tcattatcgg atgtgtgatg cctttagttc ctggagttca
     8041 aattacgaac gctatccgtg atttgctagc tggacattat gtctcaggag tttctcgcgg
     8101 aacagaagcg atgatgactg ctacgatgat cggttttgcg attgctttta ttttccagct
     8161 tttttattag gaaaggaaca caagtatggg gacgatattt attcagtttt cttttagttt
     8221 tttagcgact gcggcatttg ccgttattac aaatgtacct aggcgttcat tgatttgttg
     8281 tggtctttct ggtgcttttg gctggatgat ctactggatc tgtgttcaaa taggcggatc
     8341 tgctgctttt ggttcattgc ttggttcttt aggagtagca ttcatcagcg atcttttctc
     8401 taaacgtttg aaaatgcccg taacgatttt caatattccc gggatggttc ctctagtccc
     8461 tggtggttta gcttatcaag cggttcgaaa tctcgttact gaatcctatc gagaagcggc
     8521 tcattatgcg gtccaagcaa ttatgattgc tggagcaatc gctttaggtc ttgtattatc
     8581 agaagtcttt aaccataaca tccgtaattt caaagtaaag cgtgacgcaa tcatgatgaa
     8641 acgaaaaaaa cggcttttta aataaacgaa gtgtaacaaa gaaaaggttg tgaaagagac
     8701 gttcagcctt gagcgatgac aaaatatctc acaaacattg cgacaagtaa ccgcaggagc
     8761 aataagaagt aattatgagt attaaaaaaa gttttgtaaa aatagcttct cacattttta
     8821 cataaaattg acttaatact gagaaactga cttttgaaca ccctctatct gtaaaaaagg
     8881 ggctgcgaca tgatttttgt cacggcccct cttctttatt caaatttttt ccaaaacgtt
     8941 cgttgataat aaacgatcca tagagcggaa agtattagaa ctaaaccgat cacaggaata
     9001 ttcactaacc aaaatggata aaacaaagcc aacattccgt ataagacgat aagaataata
     9061 ctgatgatca atgaacccat catagttgcg actaaaccca aacttcctga acctctgtta
     9121 aataattggt taatattggt ccagttcagc agcagcaacc gataatctct agcgaaataa
     9181 cgtagtgaca ataagtagca gccgaataaa gaaccaaata gcaagctagg gataaaaaac
     9241 aaaggcagct gaaaagacag tccgcttaat aatgcgatcc caccagttaa aaaactctgc
     9301 aatatccatc cgaatctgaa cttttctttt aaatattggt tcatagagat tggcaaagaa
     9361 cggataaaca gaaaattttc ttgatccaaa gaaataagat tgctgataaa agaagtctga
     9421 ttaactgtta agaaagccaa tgcgatccct accaggaaaa caacaccgat taacttatta
     9481 tctaaatcag ttaattttat ttcgcctcct agggcaaaag caagaataaa aatgattgga
     9541 gttaacaagg aagaagaaag aacttgcata atcaaattag gttcttttac taattgagca
     9601 ttgtaactaa ataaaagctg atgcacattt tggttctttt tatgggttct ttttattttg
     9661 aactcactgt ttgaatcagt cagttgctct gtaagctttg gtactatcag ctgttttaca
     9721 gcaaggaaaa atcccagagc cgtgatagct agtattcccc aacccaataa accttgttga
     9781 gaaagtggct gactggcagc atcatagaat ggcaataata tcgaaatcgg atgccgatct
     9841 gttaactcat tttcaatagt ccccgtttga tgattcatcc acatgattcc agcaaatgcg
     9901 atcagcatcg agctgccaag caagatacta gaaactgttt ttctatgttt tttaaacact
     9961 gctgttcgag ccaaaccaaa aacaatcaaa ctagccagac aaaaaagaat aatcaaaaat
    10021 agagaaaaca aaaggattga gataatgata gtaagcaaaa tccctagatc agctcgccat
    10081 ccggttaaaa taaacatgac tagaagcgga aaaacaaaag gaatgatggt caaagcaact
    10141 accaaaatct ttgctgaaaa aacctgttct tgtccaaaag gcagaggcaa aaatacttgc
    10201 aggtcatttc cttcaaaaaa gatattataa atgactgata tactttgagt taaacctaac
    10261 ataccaaaaa gtgccacgta ataagtaaag aaacctggca atttaacaaa gttcatagca
    10321 aacatagcaa atccgtaaat cagtaaaaaa atcagccctg aaaaaagatt ttgagacaaa
    10381 agatagatag ttaatcgctt tccctttttt cctttctctc ttgctttatt cgtgagctgt
    10441 ggattaacat ataaaagatt aactcgaatt aattctaata attgtcgctt atacatacgg
    10501 tccatctcct gtcgcttgcc ttccagccat tttcaaataa atcttttcta gcgtttcatc
    10561 aggtgagcca ttcaataatt cactaactgc cccctgataa atcaattcac ctttcttcaa
    10621 aatagccagt ttatcgcata actgttgtgc ggtatccaat acatgtgtag aaaaaatgac
    10681 tgtttttcct tttgcggcat gagccttcat catttctttc aaatcaaatg ctgcttgagg
    10741 atcaagtcct tgcaaaggtt catccaatac ccaaatatct ggatctggca gcaacgtgcc
    10801 gatcaaaatc gttttttgac gcattccatg tgaaaaactt gcgattgttt cattttgatg
    10861 actatacata tcaaaaagcg ctgtcaattc tgctaaacgc ttttcttttt tttgtgtgtc
    10921 taattcatag gcagctgaaa tcaagtccca atattctcca gccgtcaatt gtaaaaaaat
    10981 atctggggaa tcaggcacat aaccgatttt ttgtttgata ctcaatcgat tttccgtcaa
    11041 tttcattcca tctactaaaa tcgttcccga tgatggttca ataatactaa ctaaactttt
    11101 aatcgtagtt gattttccgg caccattatg tcctaaaaat ccaaaaattt ccccttgtct
    11161 tatcgagaga gacaagtctt ttaatgcttg ttttttcccg taacttttac ttacattgat
    11221 gaattcaatc atttctgtac tccttttgtt tgttattact ttttattgta cccttcgtta
    11281 ttggtggagt aaatgtcaaa aagagtgcat aacaaaaaag gatagaaacg actaggctgc
    11341 tacttgggtt gttctcttct acaggaaaac actcttctaa caggtaagat atgagtcttt
    11401 gttttcttta aaatgattca ttttctatct tttcttgcat aaaattcttt agtttatcaa
    11461 tacttctctt tcccatctct agttgttctc catttgcaaa tgttactatt tcgtttactc
    11521 tgct
//
LOCUS       DADVXB010000089        11008 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.091, whole genome shotgun sequence.
ACCESSION   DADVXB010000089 DADVXB010000000
VERSION     DADVXB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.091"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(129..371)
                     /gene="acpP"
                     /locus_tag="KB902_001874"
     CDS             complement(129..371)
                     /gene="acpP"
                     /locus_tag="KB902_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6808695.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(493..1494)
                     /gene="plsX"
                     /locus_tag="KB902_001875"
     CDS             complement(493..1494)
                     /gene="plsX"
                     /locus_tag="KB902_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBB6808696.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(1543..3579)
                     /gene="recG"
                     /locus_tag="KB902_001876"
     CDS             complement(1543..3579)
                     /gene="recG"
                     /locus_tag="KB902_001876"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBB6808697.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(3696..5378)
                     /locus_tag="KB902_001877"
     CDS             complement(3696..5378)
                     /locus_tag="KB902_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBB6808698.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(5430..5792)
                     /locus_tag="KB902_001878"
     CDS             complement(5430..5792)
                     /locus_tag="KB902_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6808699.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            6062..6250
                     /locus_tag="KB902_001879"
     CDS             6062..6250
                     /locus_tag="KB902_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBB6808700.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            6488..9157
                     /locus_tag="KB902_001880"
     CDS             6488..9157
                     /locus_tag="KB902_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBB6808701.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(9248..9868)
                     /locus_tag="KB902_001881"
     CDS             complement(9248..9868)
                     /locus_tag="KB902_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6808702.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            9981..10520
                     /locus_tag="KB902_001882"
     CDS             9981..10520
                     /locus_tag="KB902_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808703.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            10517..10855
                     /locus_tag="KB902_001883"
     CDS             10517..10855
                     /locus_tag="KB902_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBB6808704.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         3126 a         2243 c         1974 g         3665 t
ORIGIN      
        1 ctttgcaaca taatttctgt ttatcgccag aattatcaga aaaatgactt ttacgtgtca
       61 aaaagattaa aaaaagaagg ataaaaagct gtatgcagct ttttatcctt ctttgctttt
      121 atttgaaatt atttaagatg gctgctgata taatctactg cgccaccgac tgtttcaatt
      181 tgttcagcgt cttcatctga aatttccgta ccgaattcat cttcaagctc taaaacgaat
      241 tccataatac taattgaatc agcttttaaa tcatctttga tgttcaattc atccgtcact
      301 ttatcggtat ctatctcaaa atgatttgaa ataattttcg ctactttgtt aaatacttct
      361 tcgcgagtca actttttcac ctccaagaat catacacttg tcaattacct acaccatggc
      421 taattttact ggcatttttc aggaatgtcc accttttttt caatggaacg gattgcttca
      481 gatatccaaa tactattctt cgcttttttc aaattgttcg actaattgtc caactacatc
      541 tgtctcaagc attgtgtgga tttggcggat cgtatagcga acagcatcgg ggcctgttgc
      601 tccatgagtt ttaatgactg gtgctttcaa gccaaacaaa acggcaccgc catgtttgga
      661 ataatccatt tctgctttca aagaacgtaa gccgtctttt aaaagcatag cgcccatttt
      721 tcctttgatc ccttcattta gaatagcaga ttttaataga ttcatcatat tcattgctgt
      781 tccttcaata gatttcaaaa cagcgttgcc tgtaaatcca tctgtgacca ctacatcagc
      841 cacaccattg agtagctcac gagcttctac gtttccaata aaattcaagc ttgtttcatt
      901 ctgaaggagt tcataggctt ttttcgtcac ttcactacct tttgttgctt ctgttccgtt
      961 gtttaagagt gcgacacgag gacgtccgat acctcggact ttacgtgcat aaaaagaacc
     1021 taaaataccg tattgcaaca aatgttctgg tttgttttct gcgttagcgc caagatccag
     1081 catatcgaaa ccggcacctt ctttccctac tactggcaag gtagacatca agccagggcg
     1141 ttcgatattt ttgatacgtc ctacgatgaa caaccctgct gctagtagcg cgcctgtatt
     1201 ccctgctgaa aatacagcat ctgcttcacc gtttttcact gcttgtgcag caaggaccat
     1261 tgatgcagtc ttttttcgtc gaattgcttt tactggctca tcatcactat tgattttttc
     1321 gtctgtatgg ataatcgtga tgtttttttc atttgttaag tatttcttga tttctgcttc
     1381 ttttccgtaa agtaagaatt ctacttctgg aaaatcttgc tgcgctaaag ccacgccttc
     1441 tacaattgct tgaggtgcgt gatctccgcc cattgcatct acggcaattt tcattgtttc
     1501 cactcctttt tccgtcatca gtataaagta tagcacagtc tgctaatcga aataacgatt
     1561 atcctgattt tctatttgga ggctttgcgc taaaggctga tactcaggaa gcatctgcca
     1621 atcctttatc tgccaaaggg ctgcagcctc ttctctggct acctccaaaa catttccatc
     1681 cgtcaccaag tcagcaatcg caaattgagg cagaccagat tgacggaagc caaatacttc
     1741 accaggacca cgtaattcca gatctttttc gcttagtaca aaaccattgg tggtctctgt
     1801 catgattttc atccgttcca cacctagttc atttttagga ttagcaacta agatacagta
     1861 ggaagcatca cttccgcgtc caacacgtcc acgaagttga tgcagctgtg ccaatccaaa
     1921 tcgatccgca tccatgatca gcatgacggt cgcgttcggc acgtttaccc ctacttcaat
     1981 tacagtagtc gaaactaata tctgcatctg gttgtctttg aaggcttcca tgattacttc
     2041 tttttcctga ttcttcattt taccatgtaa caagccaact tcatattttg gtgcaaatag
     2101 ttcacgaagt ttttcataga tttccactgc attttttaca tctaatgctt ctgattcttc
     2161 aatcagcgga cagatgacat acatttgatg tcctcttgcc agttcttttt tcgtccaatc
     2221 cagtacactg tccaattgag gtgttcttac ccagcgtgtt tcgatcggga tacgtccagc
     2281 tggaagttca tcaatgatag atacatccat ctcaccatat gctgtaatag ctaatgttct
     2341 aggaatcgga gtcgctgtca taaataagac atctggtcgc cagccttttt cacgaagtac
     2401 tttccgctgg ttcacgccaa accggtgctg ctcatccgta ataactagac ctaaattctg
     2461 aaattcgact ccatcttgga tcaatgcatg tgtgccgatc acgatgttaa tttccccttg
     2521 ctctagtttt tcaaggagct cccgacgttc ttttgctttc gttgaccccg taagcaatgc
     2581 gatggttact tcattgggat caaacagctg ttgcaagctt tccatatgtt gttgtgccaa
     2641 gatttctgta ggcaccatca acgcaccttg gaaacctgct gtaacggtag cgtataacgc
     2701 aatcgcggca accactgttt ttccgctacc tacatctccc tgcaaaagtc gctgcatatg
     2761 ctgcggactg cgaagatccc gacagatttc attcgttaca cgtttttgtg catttgtcag
     2821 ttcaaaaggt agcttttgag taaattcttt caatttttgg acatcataaa ggatctccaa
     2881 accattcgtt tctgcttttt ctgctttttt caatccttga agacgcattt gaaataaaaa
     2941 gaactcttca aaaacgacac gtcgtttggc ttgatggttt tcttcgtggt cttttggaaa
     3001 atgcatactt cttacagcag aagctcggtc aagcagtcga tatttctcca caaggttgtt
     3061 tggcagattt tcttcaatca atgtgccgta ttcttgaaac ccttttttga ttagatcaac
     3121 taatgtcgtt tgacgaattg atttgttgac gtgatatatc ggcgaaaagt catccattgt
     3181 ttgagaacct aaaatcttca tcccgttcaa tgctttacgc tttgcatccc atttaccgta
     3241 tacggcgatt tcctccgata aaatgacttt ttcttttaga taaggttgat taaaaaaaga
     3301 aacgttgaac acatcatgtt cttgcatcat acgaaattgc aatcggcttt ttttataacc
     3361 aaatcgattc atcacaggag gcgagactac gattcctttc aaagtaacct tttcttgatc
     3421 ttggatctcg tttagatttc tttcctgaat atcttcgtag cggaaaggat aataagtcag
     3481 taagtcttca atcgtttgga tgcccaagct ggcaagacta gctgctcttt tttctccgac
     3541 tcctgccagc atagtgattg gatcatctaa agaacgcata aatttttcct ccctccttta
     3601 acaaaaaaag gacttggtca gcgatcatac ctgatcacta accgaaggcc ttttatgaat
     3661 gaatactgtg ttagaaagat attctgacac agaaattatt cagcagaaaa tagataagga
     3721 tagacaggct gatctccttg gtggatctcg atttccaaat caggatgttt ttctgttagt
     3781 ttctcagcaa attcatttgc ttgttcaact gttccttcat cacctgccaa gatcgttacg
     3841 atctctgtgt cctcattgat catttgttct agtgtactta acgctgttgc tgtgatatct
     3901 gggttagaga tcaggatttt tccatcgatc atgcccaaaa agtctccttc tttgatctct
     3961 acaccgtcaa ttgaggtatc tctgatcgcg tgagtgactt gaccgctcac aacgctagac
     4021 aacatttctg tcatcgtttc tttgttttct tctaaagaag cttgatcatt gaatgaaagc
     4081 atagctgtca atccttggga aatcgttctt gaaggaacaa ctgctactgg gatatctgct
     4141 acttctgctg cttgatcagc tgccatgaag atgttcttat tgtttggcaa gacaatcact
     4201 ttatctgcgt ttacttcttg aatcgcttta acaatgtctt ccgtacttgg attcattgtt
     4261 tgcccaccac tgataacata attagcgcct aaactttcaa acagctcttg gacgccttta
     4321 ccagcagcga tcgctacgat accatacggg atacgtggtg tttctttttt cgcaaactcg
     4381 ttcacttctt catcgtgttc caaaatcgtc tcatgctgca agcgcatgtt gtcgactttg
     4441 attttgacta atgaaccgaa tttttgtcca taattcaaga cttctcctgg gttttctgta
     4501 tgcacgtgga ctttgatgat ctcgtcatca ttgaccacaa gtaaagaatc tcctatacca
     4561 tctaaatagt tacggaattc ttcgtaatcg aatgtactat cgactgtagg tccttctccg
     4621 atttttacca tgatttctgt acagtaacca aaatggatat cttctgtcgc catttgacct
     4681 tggacactgc gatgatgttc tgcattgacc atatcatcca tttctgctgg agaaggttca
     4741 tatgtttcat ccgcttggaa ttctccattc aatgcactta aaaagccctc ataaacaaac
     4801 agcagtcctt gccctccact gtctacgaca ccgacttctt ttaggactgg aagcaagtct
     4861 ggagttttag ctaaagcacg ctttgcccct tttacaacag ctgtcattac ttcaacgaca
     4921 tcatcagtac tttttgcttt cttttctcca gctttcgctg cttctctagc tactgtcaaa
     4981 atcgttcctt ctactggttt cattactgct ttatacgcag tttcaactcc atgagtgaag
     5041 gctgcagcaa gatcggaagc atttaatgag acaacatctg gaatttgctt agaaaatcca
     5101 cgaaacaatt gagacaaaat aacgccggaa tttccgcgcg cacccatcag caatcctttt
     5161 gaaagcattg ctgctaattc tcctactttt tctgaggttg aatctactac tgccttagct
     5221 ccactagtca tagatagatt catatttgtt cccgtatcgc catctggcac agggaataca
     5281 tttaatgaat tgacgtattc tgcatttact tgcagacgat tcgcacctgc ctggaccatt
     5341 tcctggaact ggcttgcact tatttctgtt acactcacct agataatcct ccttcagatc
     5401 gactgctgag ttaccagcca gtctcctgcc tagtctggca gtacacgaac accttgcaca
     5461 aagacattaa ctgaattggc agttacgcct aataatgcct ctagattgta tttcactttt
     5521 tcttggacgt tgcgggaaac ttcagagatt ttcgtaccat agctgataat cgtataaaca
     5581 tctacagcaa taccattatc ttcttggcgg acaactactc ctcttgagta attttcttta
     5641 cgcaaaatct cagtaatatt atctttaatt tgatttttgc tggccattcc tacaacaccg
     5701 aacacatctg tcgcggcgcc accaacaact gttgcaatta catcattggt aatttcaatg
     5761 gttccagctg acgtttgaat ttttacagcc atgaatgagc ctccttaacg ggtaaaaaac
     5821 tcccattttt cttctatcat attttatcat agcgcaactt gaaataaaag gcagttaccc
     5881 aaagtactca aaaaccttgc aaaatttcag gtataacctt gtttaattta caattattct
     5941 tctcaattgt caattgtatc tatgaaaatg tacttgcaaa tttccattct atatgatatg
     6001 ttagtctggt atgagctgaa ttattctatt gctccaaatc aaggcaaagg aggaaattac
     6061 catggcaaaa gtttgttact ttacaggtcg caagacaaaa agtggaaaca accgttcaca
     6121 cgctatgaac tcaacaaaac gtactgttaa acctaactta caaaaagttc gcgttatggt
     6181 cgacggaaaa cctaaaaaag tttgggtgtc aactcgtgct ttgaaatcag gaaaagttga
     6241 acgcgtttaa ttgaatgata cttggaccgt tcagatagtg aacggttttt tatttaataa
     6301 aaatttttaa gggtgggact tttgattcct accctttttt tgcgtttatt tttgttatac
     6361 gaacaaatta tgaagttatt tattctaaat tttatttttt tgtgaaaact agactctttt
     6421 taagcagaga aaaacaagga tatgataaac tgaatacaac ttcatagaaa tttggtggaa
     6481 aataaatatg aaaaaaaatt taaagtcatt ctttagagaa aacggacgct acgcagcagc
     6541 tagtttcctg attccgtttt tgattttagc acttgtttat ctaagtatcg ggatctatcc
     6601 tggaagcagc agaagtattt tggcaagtga tgccttttca cagttttcta attttcatgc
     6661 cagcttccga aatgttcttc ttggaaagca aagtattttt tatacatgga atgcttctct
     6721 aggattgaat tatttatctt taatttctta ctatctaggc gggatcttca cgccactggt
     6781 gttctttttt ccaaaccaga tgatgccaga tgcactgtat gttctgactt tgcttaaggt
     6841 cggctgtgcc ggattggctt tttggtttct tgcacgtacg ttcaagattc ctcgctgggg
     6901 gcatgttgca cttagcgtca gttacgcatt gatctcattt atcactgcac attcggagat
     6961 catcatgtgg ctggatgcat ttgtttatct tccattagtg attttgggga ttcatcgtgt
     7021 tatggatctt aaacggccga aacttttatt tatcagttat ttactcttgt ttttatccag
     7081 tttttatatg ggttttatga ttggcgtatt ttctttctta tattttatcg cccgtctatt
     7141 gacaaactgg tcagaatata aaaaaacgat tgttccttat ggtatcactt ctttactggc
     7201 aggcggcgct tcaatgatca ttgtattgcc agcagtgctg gatcttcggt caaatggcga
     7261 ggcactgagt cagatcacta cgttgaaaac agaagcgact tcttatctgg atctaatcat
     7321 gaaaaatatg attggtgttt atgacacgac aaaatacgga tcgattccgt tcgtttacgc
     7381 aggtctgcta ccattagtcc tctgtctgtt ttattttgcc agtcggaaag taccgttgaa
     7441 aaataaattt ttgtacggca gtcttttcgc catacttatc gcaagtttct atcttgttcc
     7501 attgaatttg ttctggcatg gtatgcatgc accgaatatg tttttattcc gttatgccta
     7561 tctgttctct ttcttagtgc tcctgcttgc aggaaaagga tgggaaaaga tagaacaaga
     7621 cgatcgtggg ctgttgttag gaatcatttt ggtcgtagct gctctctttg cggtggcatg
     7681 gggcatcaaa cctgaaggaa gctacaccta tgtgacgatg acttcctttg tattgacagt
     7741 ggttttctta gggatttatg cttttgctgt gggattttat cagcataaaa aactttcatt
     7801 caatcatctg agtatattgt tattattgat catgtctgct gaagcactgg tcaatacgaa
     7861 cagtatgatc catggcattc ttgatgattg gaattatgct tcccgcagtt tatatactga
     7921 tccttatcct gacttgaaag ctcttgtaaa tgaaacaaaa aaagattccg actcgtttta
     7981 ccgcttggaa aatctggatc cagtatctgc aaacgattcg atcaactatg gttacagtgg
     8041 tatcagtttg ttttcttcta taagaaatcg taattcttcc tcttacctgg ataaattagg
     8101 tttccgttca agagggacaa atttgaatat ccgttataac aataatactt tgctaatgga
     8161 tgggtttaca ggaatcaaat ataacatttc taaaaacgaa agcacgttca gtaaatatgg
     8221 cttccgccaa gctggtcaaa gtggcgacta tacactgtat cagaatgtca atgcattgcc
     8281 actagcattt actgcaccgt tgtccgttaa tgatgttgag cagccagtga cagataattt
     8341 gaccagtcag acaaacttga tcaatacatt gtctggttta aatgaacagt attttacatt
     8401 ctatacacct actttgaaga atcagttgaa tacgacgatc acaaagacaa cgactggcgt
     8461 cacttactca gaaacagcag ataaccagcc aaaagagctc acttgggaag tccatgtgcc
     8521 tgcaaataca caagcttact taagtttgtt cccaaccaat tttgcacaat tagaaagttc
     8581 tagtgcgacg atcactgtca atggtacatc gcgaaaaacg caaatcaaca tttctggtca
     8641 atactatgat cttggctatt atcctcaaga gacaacagtg acatttactg caagttttta
     8701 tggaacgaaa gaagtaagtt tcatggagcc taaagtcgtt ggtctagatg ttgtagccta
     8761 tcaagccgca atgaatcaga tcaaagaaaa aggtgtcgaa atggaagcca ctggcagaaa
     8821 agcttctggg actgtaaata ccgctgaaga ttccatgttg gtgacaacta ttccttatga
     8881 caaaggatgg aaagctaaaa ttgatgggaa accagtcaag gtcagcaatt tcaaagacgc
     8941 attcttgatg ataaaagttc cagcaggtaa acatactgtc actttcagtt acttgcctga
     9001 aggatttacg ataggtgcaa tcctttttgt cctatgtatt gcattgttta ttctttatgt
     9061 ctggtacctt gaccgcaatc gcccctttta tggcacgatt gatccagcaa tagaagaaaa
     9121 accgcgaaat acacacagaa gaagacgaag aaaataaaga aacgatggaa tctgtgtcac
     9181 tcttctattt aaatggcaaa aatttcaatc tttaaatgac aaaaaccacc tgatttttgg
     9241 tggtttttta tatacctatg actaaactat ctcttgctgc ttcgacaact tctacagtga
     9301 tcttatccat ttgattgatt cttaaaatcc gatcaatctg cgcaaataaa cgatgaataa
     9361 gcctaaaatt tccttttgtg atcttaatga tagttgtgat agcctcataa tcagaaaaat
     9421 cttctagctt gatatcaatt cctaaatctg cccatttgta ttccaaaata tgatgtgttt
     9481 cgtccttact aaggttatca aattcatgtg caaatcctat gcgagagtaa agctgcggat
     9541 aacgagacaa tcttttttca ataccaggca taccgataag aaccattgcc agatcatttc
     9601 tatcgtaaat atctcttagc tgttctaaat gctgaagctt taaacgatca atttcatcga
     9661 caataattaa gtcaattgct tcataggttt taggcacagg aggatcttct tgattgtatt
     9721 ttagtaccat atgcattgct ttagtcagac ctattctact agttattgtg ttaatatccg
     9781 aactgacacg agacatcttt tcagctggta cagtataaaa aactttattt acacttaata
     9841 tttcatctgt tgcatttatc aagaacaaga aaaagtctga atattcaaaa aaataacggt
     9901 gtacattttt aaaaggagat gtataatcga gattgagaaa gcgttttcct caaaatttaa
     9961 tgaattagga agtgattact atgaaaaaat tatttagcgc actttttatt ctgttatttg
    10021 gttttattgg tattgggact tctggaaata tagttaaagc tagcacgatg gttgaacaaa
    10081 caagtgaaat ggcaaaaact tttagtcaat taacaccaga agaacaaagt tacttcaaat
    10141 ccaaaggatt tagtgataaa gatacttttt acactcaaaa gatagagcct caagatccga
    10201 aaacacgttt ttctgcaaat gtattgcggt taaccgcatc tactaaaaaa attactaata
    10261 cgcaggggcg gacagaatat attataacaa gtcccaattc ggcgatgtat cgtatttcta
    10321 cacgcttgag tttaggtagt gcaaaatcat atactcaaac agtaaatcta gctaattctt
    10381 atggttatgg tggaggaatg tattttacat ttactgggaa aagacaatat tacagtgtaa
    10441 aattagctat gcaagtttat aatacatttg gtgtagggtc agtctcttgc actgcgggag
    10501 gattgacaat aggaaaatga taatttctta ctatgtctta aatagaagtg atgatgaagg
    10561 actcttcgtt tttcaatcat tacatgagga tacgatgcta aaagagtttt ataatcggat
    10621 taagaataaa cagatagaaa caaatttata ttttttaagt gactctatct tgccttttat
    10681 tagcaaccct aaaattctta acttgttgca gacaaaagat ttgaaaagtt taccgattat
    10741 tgtcattgat gaggaaattg taaaatatgg cgcttatcta agcgtagaag aattagaaaa
    10801 attaactaac attggaatga gtattcagga ggataatggg gtacatggaa catagaatga
    10861 atatgcacag ttgagaacgg aatttgacat ttatttagac caacagggta taccctgttg
    10921 gtctttttgt gcgttcatga tatacttggt gtcattttta tatttaaatg gcacaaatat
    10981 ttctaattat ttgtcattta acgctgaa
//
LOCUS       DADVXB010000090        10989 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.092, whole genome shotgun sequence.
ACCESSION   DADVXB010000090 DADVXB010000000
VERSION     DADVXB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.092"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(90..1127)
                     /locus_tag="KB902_001884"
     CDS             complement(90..1127)
                     /locus_tag="KB902_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6808705.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1574..2557)
                     /locus_tag="KB902_001885"
     CDS             complement(1574..2557)
                     /locus_tag="KB902_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBB6808706.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSSAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(2970..3740)
                     /locus_tag="KB902_001886"
     CDS             complement(2970..3740)
                     /locus_tag="KB902_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808707.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(3733..4668)
                     /locus_tag="KB902_001887"
     CDS             complement(3733..4668)
                     /locus_tag="KB902_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808708.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(4984..6633)
                     /locus_tag="KB902_001888"
     CDS             complement(4984..6633)
                     /locus_tag="KB902_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6808709.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAASFDEKRQWHVLG"
     gene            complement(6828..7724)
                     /locus_tag="KB902_001889"
     CDS             complement(6828..7724)
                     /locus_tag="KB902_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6808710.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNRWVDENEQKGQVFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(7717..8397)
                     /locus_tag="KB902_001890"
     CDS             complement(7717..8397)
                     /locus_tag="KB902_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6808711.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILMDKESRDVNVNGVTVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(8398..9180)
                     /locus_tag="KB902_001891"
     CDS             complement(8398..9180)
                     /locus_tag="KB902_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808712.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(9173..10090)
                     /locus_tag="KB902_001892"
     CDS             complement(9173..10090)
                     /locus_tag="KB902_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6808713.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(10093..10308)
                     /locus_tag="KB902_001893"
     CDS             complement(10093..10308)
                     /locus_tag="KB902_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808714.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWQTTQPRLRDSLIFLEIQLE
                     NLHFLYTFLAAFFIPVNYTSLINKKEG"
BASE COUNT         3239 a         2427 c         1917 g         3406 t
ORIGIN      
        1 aataaaaaaa caagagctta tggcaaatta ctgtcatgcg ctcttgtttt tatcaaagtc
       61 aaataagaaa aaaatcggcg tattcttgct tatccgttga acggaccact aacaacgact
      121 tttcctaaca tatgtcctgt ttctacgtct ttggttgctt gtttcaagtt cttcgcattc
      181 atcccatctg aatagacctt gctcaatgta ctgcggataa tcccttcatt tgctaaagca
      241 gcaatgtgcg ctaaagcttc tccttgcgtt tcgatttcat agttatagtc tgttttagcg
      301 aacatatact cccagtcgaa gctgatagat tggtttttcc aaacacctat atctaacggc
      361 tctttgatcc ctacgatcgt tcccacatgt ccaaatggtc ggacaaggtg cttgatttga
      421 tcaaagtagc gggtaatatc gaataataca gcgacatact ctacttgatc gattcctaat
      481 tcacgaaaac ttttacttaa gtcgtgatga taatcgattg gatagtctac acctgttttt
      541 ttcagccatt caaaattctt cggacttgca gtcgcgtaga cttctaggcc agcccaatgc
      601 gctagttgat tcaaaatcga accgacgccc ccggatccgt tgatcactaa gatttttttc
      661 ccgcgattgg cattttcttc tggagttaga ccaaattttt caaataacaa ttcataagcg
      721 gtcaatgagg tcaacggcaa ggctgcagct tcttcatctg aaagattttt tggtgcaaga
      781 gcgacaatac gttcgtcaac tagttggtat tcttgattgc ttcctgctct tgttgttgta
      841 cctgcgtaaa aaacgcgatc gccgacagaa aatttttgca cttcgtcacc tacagcaaca
      901 actttcccga ctccatcaaa acctaagata cgtaaagcat ttcttatccc gttatcttgg
      961 cgaagtttcg tatcgacagg attaacagat actgcgttga cttttaccag aagatcccgt
     1021 gaactgggta caggtatctg ttctttttca tcaataaagc tttttggatc atcgatcggc
     1081 aacccttcat aaaaaccgac taccttcatt aattcctttt ctgacatacg aattcctcct
     1141 tagcttcatc aagttggagc atccatacag tgttcatttc aatatatata gtatgctatt
     1201 tgttccacct tttttattca tcataattat tctcttactt aaagtaaact atttgcactt
     1261 ttttggttaa aaaagaggtt gcgacaagac ttttgtcaca acctcttata aacggtgttc
     1321 tcctaccaac tcttcggtca caagtcaaaa tattcatcaa acatgagaag ctgttttttg
     1381 aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctgat ataaacggtg
     1441 ttcaatcaac tgaccctcgg tattagctca aaaaacgaca aaatatgaag agctattttt
     1501 gtttggctgt tcttattact tgatgcagga cagctttttc acgacctcta attcacggtg
     1561 ttcaagcaag aaatcattgt tcactgaaaa gcgttggatg ttctttttca aaagtgtcta
     1621 agatctctcg tacttcatca gtagatttcg tattcatcaa ctgaactcgc aagtcatttg
     1681 ctcctggaaa tcctttgata tagattttaa agaaacgatg tagtcctgtg atggaacgcg
     1741 ggatgatttc tgaataatga tcttgcagat ctagttgcag acgaagtagt ccgatcagtt
     1801 ctttttctgt atgttccctc ggatcttttt caaatgcata aggattcttg aaaatccctc
     1861 ggccaatcat gatgccatca acgccatatt tctcggccaa ttcttctcct gtctggcgat
     1921 cggggatatc tccattgatc gtgattagtg tttgtggagc gatttggtca cgtaaagcaa
     1981 tgattttagg aatgacttcc caatgtgcat ctactttact catctcttta cgcgtacgca
     2041 aatggacaga aagattggct atatcttgat gaagtaggtg actgatccat tcttccatct
     2101 cagacatttc cgtatagccg atacgcgtct tgacgctgac aggcaaaccg ccagctttag
     2161 ctgcttcaat caattgtgcc gctacttctg gacgaaggat caagccactg ccttttccac
     2221 gttctgctac attagggact gggcagccca tgttgatatc gattccttgg aagcccattt
     2281 ctgccatagc actgctcatt tctctaaaaa attctggctt gtctccccaa atatgggcaa
     2341 ccatcggctg ttcatcttct gtaaatgtta atcttcctcg tacactgtct tttccatctg
     2401 gatgacagaa actgtctgag tttgtaaact cagtaaagaa gacatccggt gctgctgcat
     2461 gctttacgac atggcgaaat acaacatctg ttacatcttc cattggtgct aaaacaaaaa
     2521 aaggctttgg cagctctttc caaaaattag tagtcattta tttgttactc tccattctat
     2581 caagcagtga agtcgcaatc tttctcaaaa acattgtcat tatactagga aacaaaaaaa
     2641 gaagcaaagt gaacagctca gaaggtttgt ctgattgaac aaaaagagga ctgtgacaaa
     2701 aatcttcaca gtcccttttc cggaataaat ggtgttctcc tgccaactcc tcggtcacaa
     2761 gtcaaaatat tcatcaaaca tgagaagcta tttttgtttg gctgttctta ttacttgatg
     2821 cagaacagct ttttcacaac ctctccacta aacggtgttc aatcagctga ccctcgatat
     2881 tcgctcaaaa aacaacaaaa tatgaggaac tatttttccg tttgtttctc taatactcag
     2941 gtcaaaacgc tgatttcaca acctcttttc taacttctca atcctcttcc tttattgatc
     3001 aaataccaag taacggcgta caaaacaacg atgaataaca caagtacgat catcgatgtt
     3061 gctactggca catcgatcgt tccaaggaat ccgtaacgga aaccggagat catataaacg
     3121 atcggattga ctttcgaaac agcttgccaa aagggcggta acatagagat ggcatagaaa
     3181 acgccaccta gataagttaa cggctgcaag acaaatgtag gtacgatcga tacatcatca
     3241 taagactgag caaaaatccc gttgagcagt cctgctaacg aaaacaagat tgccgtcatc
     3301 aataatgtaa tgatgaccat gaaccatgaa tacacatgaa gtggtacaaa gaacaaggaa
     3361 atgatcgtta cgagagagcc gacgagaata ctgcgaccca caccaccaat cacaaagccc
     3421 caaataatca catgcgtagg aacaggtgct accaagattt cttcgatatt tttctgaaat
     3481 ttttgagaga agaaggacga agaaacattg gcatacgaac tagtgatagc agacatcata
     3541 atcaaaccag gaacgatgaa ttccatatat gaaaaaccac ccatgtcacc gatccgccca
     3601 ccgatcattt ttccgaaaat aacaaaatac aaggatgtcg tgatcactgg cggaaccagt
     3661 gtttggaccc atatacgcaa atagcggttc gtttccttga tagctaaact ttttaatgca
     3721 gtaaaataaa gattaaacat ttttctcctc cgtatgatta ttttcttctg tgattttcaa
     3781 gaacagttct tctaaacgat tcgacttatt cctcatagaa agaactttga ttccttgtct
     3841 tgtaagctga tcgaagattc cgttcacccc ttgatttcgt tcaacttcga cagcgattgt
     3901 ctgctcatct tcaaatgtac aagcatatcc ttcaatcaca ggtttggtat catatggcgc
     3961 taaatcaaag ataaatgttt caaattgcag ttttgacaga agctctttca tacttgtatt
     4021 ctcgatcagt tcacccgatt ggatgattcc gatgttgcga caaagcattt cagcttcttc
     4081 tagataatgc gtcgtcaaaa tgatcgttgt accattttcg ttcaattctc gtagaaactc
     4141 ccacatctcg cgtctcaact cgatgtcaac tcctgctgtt ggttcatcta aaatcagcaa
     4201 acgtggttca tgcatcagtg ctctagcaat catcagtctt cgcttcattc ccccggaaag
     4261 catacgtgca cggacatttc tcttttccca aagattggac tgcttcaaat atttttcact
     4321 gcgtttcatc gcttctttgc gagaaacacc gtagtaaccg gcttgattca cgacgatttg
     4381 ctggaccgtt tcaaaagggt taaaattgaa ctcttgtgga accaatccaa tctgttgctt
     4441 tgctcgaact agatccttgt ccagatcata accgaagaca ttcacttttc cagatgtttt
     4501 attgactaaa gaagtaataa tcccgatcgt tgtagacttc ccagctccat ttggccctaa
     4561 tagcgcatag aaatctcctt ctttcaccga aagatcgatt ccccgcaatg cttcgacccc
     4621 acttccatag atctttttca aattatttat ttcaagcgca tttgccattt atttcctatc
     4681 tccttataga catgattctt tattgtatca tggaatacag cagatgaaaa aacaacttgg
     4741 ttccagcgaa aaatcaggtt gctgggctca ggaaaatctc ctaatgaaag acatcaatcg
     4801 gacgaagtca gacaaccttt tcagaaaaaa caaatcgaag ataaaggatt actattcata
     4861 tgtgcaacaa aaggagcgtg agacaaaagt aaagaacact tttgtctcac gctctaaaca
     4921 cgtataaacg gcggaagcat gagccaagat ttttgatcca ataaatactt tcgatcactt
     4981 cgcctatccc aatacatgcc actgccgctt ttcatcaaat gacgcggctt ccgtttttgc
     5041 ggtttctact aaagtctctg ggtaatccaa aactttcagc aaggcaatcg catttcgggt
     5101 ccttgaaggt ccttctttta atttgaaatc aaaactgatt ccttttcctt ctgttacttg
     5161 ttcttcaaag tggacattct cacaataatt ctttaaaatc tctgtcaatt cgatatcatg
     5221 tgtggcgaca aatgctaaag atggatactc cgcaagccac cgaacgactg aagcggaaga
     5281 agcaatccgt tcgatcgtat ttgttccttt taaaatctca tctacgaagc agtagcagcg
     5341 ttctttggaa gccacttggt ccagcaaacg tttgatcgat ttgatttctg aaacaaaata
     5401 actgtcgcct tcaaataaat catcttcgat tgccatggaa gtcaacacat gtccaggttg
     5461 cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt gctagaatac agctgatggc
     5521 tatacttttg acatacgtag attttcctga tgcattggaa cccgtgacta atgtattctt
     5581 ctgccagttg actggattca ctaccgcttc ttttaacaat ggatgataga tatctttcgc
     5641 tgtcacaccg ccctcagtaa actctggtcg gcaagtgatc ggcatatagg tgcgataatt
     5701 caaaacggct gctgcaactt ccaattctcc cagcaattcc cacagcttga tggcttcagt
     5761 tgaatgcttt tctaatttag tgagaacgaa atgataggag ataaatggta gcatgaacat
     5821 gatgttgaca tattcaaaaa tcaattctgc ttcactcccg ctcttcattc gaaatgaaaa
     5881 acctaattta gggatgtctc ttaatggttt agtttgctgt ttcagctctt tttgaagtgg
     5941 tgtcgtcatt tttgctaact gattggcggc tgaaatcgtt gaaaccaaat aactcatgct
     6001 attcagctct gtttctagtg tttgtttctt cactagataa tagaccgtat tgaatactaa
     6061 gccaccgatt gctagataga ttcctagtac ttgacctaaa agaagcaaac ctacacccac
     6121 cagcggaagc aagccaagaa aaataaataa acctacgcgt ccaatctttt tactttttcc
     6181 atccgctaga tattgttttg caaaattatg atcttttttt cctaaacgag cgaattgata
     6241 ttggattctt tctctcagtt gaggattttc ctgataaaaa gcaattagtt tttctaactg
     6301 ataatcttct ccaaaatcaa agctacgtaa acgctgatac aacgcttctg aacctacact
     6361 agaataggta ctgttgatcc cttcaaatac ttcgaacata tccaagtcat accaagtaag
     6421 atcgtcgatt tcactatccc atgaacggaa ttttttctcc gtgagccacg catccttcaa
     6481 actttcttct ttatcaaatc tcggttgata aggaattttt ccccaattac tacgaactgt
     6541 ttcctttact ttcaaacgtg aaaaaatgtc taaaacaact aataaaataa caactgcaat
     6601 aataattaaa acgataaatt ctctttggcc catatccctc tccgttcctt gatttgttag
     6661 ttttagtata gcactgttgc gctatttgaa aagggggtac aaaaataact atcttcgtta
     6721 cctaattcgt atcaatcaca ccaaaataaa aacaccttcc aaaaaagaag atgtctttaa
     6781 aacgagatac aattttttgt cattcacttc aggtaaatta gagccaatta aaccctccgt
     6841 aacttgacgg agatggagaa gatgcccccg tctaatctag cggtcatctc tcctcccatt
     6901 ccttccacca atttttttga caggtaaagc ccgattccgc tagattccgt atttgtgcgg
     6961 ctggtatttt cggtataaaa acgctggaag actttttcaa cagaggtttg cgctcctggt
     7021 ttgataggat tggccactgt taatcgaatg aatggatcct cttttgaaaa tgtcaccttt
     7081 gcttgtccat ctgcataacg caataaattc tgtatgatat tttgcagcac tcgcagcaac
     7141 atgagcggat ctgctaatac agttgtattt atcgagtgtt cagcgaacgc tacctcgata
     7201 tttttctcag aaaattgttc ataaaaagag aaaaatactt cttccacctc tttagaaaaa
     7261 gaaagcgtat ggagatccat ttctttttgc ttcgtctcta ttcgagcaag atcataaaac
     7321 tgatccgtca tactgagtaa tcttgcaaca gattgtttga tgatcgttaa atacttctcc
     7381 cgtttctccg tatcctctac ctgttccagt aattgtacat aaccgttaat agcagtcaaa
     7441 ggagttctga gatcatgaga aaggccgacg atcgatagtc tgatgttttc ttccatttct
     7501 tgaaatactt gtcctttttg ttcattttca tccacccatc tattcagtgc atctactagg
     7561 tccattagat tcttttctcg aaattcgact gaaagacgac caccatattc ttgtcgttca
     7621 gaaagagtgg cgattttctt agttaatcgc ttgatttccc tttgcaggaa gaaaataaaa
     7681 cttcccataa agataacaac gagaagcaac agccacttaa tcaaatctaa accccactcc
     7741 ccacaccgta tgaatataca cagcatgtgc ctttgctagc ttccctcgaa gattggaaat
     7801 atgcatattc actgttttct cactatcaaa atatggttct tgccaaactg tttcataaag
     7861 atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa agcttcagca gatcgaattc
     7921 tcttcctgtc aaatggacag tcacaccatt cacatttaca tcccttgact ctttgtccat
     7981 taagatttcc ttgtaataga tgcgttgcga cagatctttt acttggacag aagtctgatg
     8041 acgaagttgg atgccgattc gtaacaacag ttcttcgata tcaaatggtt tcgtcacata
     8101 gtcatccgct cctgctgcca acaaggaaac tttatctctt tgatcgcttt ttgctgaaag
     8161 aacgatgatc ggaacattcg atgtctgtcg gatttctgct aacaatgctt cacctgaaag
     8221 ccctggaagc atgagatcta gaaggatcaa atcgacagga tatgtgctta acaataattt
     8281 tccttccgta cctgaataag catcaagaag tttgtatctc tgttcaagaa cctcctccag
     8341 taaagaatga acagcttcat cgtcttcgat aatcaaaata gtttccagca ggaccaccta
     8401 cttaatgtca gatttttgga aaataaacat tcctagagct gatgatacca cgattgttac
     8461 tagactgacc agaatcattt tcggtgcttg cgaataagtt gcttgttgcg caaagtccgt
     8521 atacatgagc cacgtttccg taaaccactc cgttagaaat tccaagcctt tgatttttgc
     8581 gaaaacaccg ggaacgaagg ccgttcccat gatataaaga aaagaaagaa gcaaactgac
     8641 actggtactt ctagtgatga atgtcaaagc cactggaaca gataatgtcg ctaatatcag
     8701 cagaagcaat acaggaaata cttttagaac ataatttcca tagtttttga ttccctcaac
     8761 ttcaccaaat ccgaaagcaa gtgtgtaagc aatcatggct agccccgtaa tcaaaaccac
     8821 gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac acataataag tcattcgatt
     8881 ccgtcctaaa gataacgtat tgcgaatcgt accgttttga aattcttccc caatataaaa
     8941 gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc attttttcca ccattaaaat
     9001 ccctgttgca ccgttgatga ctgtatccgt tgcttggttt aattcattgc cgtattttgt
     9061 atgcatatac cattcgttcc aagaataaaa aagcggaagt acgaccatca gtcctagtga
     9121 gacccacatt ttacggctct tccatacttt tattttttca gcagttaata gattaaacat
     9181 gtggattgcc tccagttaat tgtaagaaat aatcttccag tttttgccca actaggtgga
     9241 taccatccac aggaactttt gcctctacca atgcttgatt gatggctgct acttggtcaa
     9301 ttccttcaaa aagctggata acacggctag attggacaaa ataatcccta taaccaagag
     9361 agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc aatttttata aattgacgag
     9421 attcttgtgc caattcttct ttcgataatt ctttgatcaa gtgtccttca tgcaaaatac
     9481 cgtagtgagt ggcgatctgt gacaattcat ctagcaagtg gctagaaagc aagacggtga
     9541 tgccccgttc ttttaccaaa cgttggatga tttctcgcat ttctgccatc cctgctggat
     9601 ccatcccatt cgtcggttca tccaaaatca aaaattctgg attcgtgatc agtgcatttg
     9661 caatagctaa acgctggcgc atacctaaag agaaattctt tgctttcttt ttccctgtat
     9721 tttccaatcg catcattttc agcaggtctt cgatttctct atccgacaca ccgccgttcg
     9781 ctgcttggat acgtaagtta tctcttgcag ttaattctgg ataaagagca ggggtttcaa
     9841 tcgattgacc catacgtcgt cttgctgcct gcaaatccgt cgttccaaat aattcgatcg
     9901 aaccttcatc aatcgagatc aaacccataa tagttctcat aaaggtagac ttacccgctc
     9961 cattctcccc aatcaaacca tagatcattc cacgtttgat ttcgatcgat actttatcta
    10021 atgctttggc agcaccgtat tttttggtta taccagttgc tttcaagacc gtttcatttc
    10081 caaaatccat acttatcctt ctttcttatt gataagtgaa gtatagttga cgggtataaa
    10141 gaaagcagcc agaaatgtat aaagaaagtg taaattttcc aattgaattt caagaaaaat
    10201 cagactgtct cgcagacgtg gttgagttgt ctgccaatca aagagcgcac caaacagtgc
    10261 taatccaagt ggactggcca ccatggtaat cgttgttatc gttgacatca gacgtccttg
    10321 tatatgcgtt ggaacttctc gctgaagcta gaccatataa aaagcaaaag aaaacattaa
    10381 tccttaaaaa cggacttatg aaaaataata catgccgttt gggatttaca attagctacc
    10441 aaataagagg ttatgacaaa agacttttca caatcccttc ttccgaataa acggtgttct
    10501 cctgccaact cctcggtcac aagtcacaat cttcatcaaa catgagaagc gatttttgta
    10561 aattccttct tatttcttga agctgaccac ttctgtcaca acctcagaag cggataaata
    10621 atattgtttg aagatacttg atctttttcc cgtttgttta tagatcgaat gatattatag
    10681 accaagaatc ctacctatta acatagctaa aaacacaaaa aggcactttc caaattgtgg
    10741 aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg cccagtacga
    10801 ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagaa ctgtgaagct
    10861 ttacgggctt tcttaagacc tggttttttc ttcgtatcat tgaataagtt tgaaaagcct
    10921 tgatttataa aggtttttcc gtaaatatat tttgttatat ttgattaaat ttgaaatgtt
    10981 tgtgttcta
//
LOCUS       DADVXB010000091        10838 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.093, whole genome shotgun sequence.
ACCESSION   DADVXB010000091 DADVXB010000000
VERSION     DADVXB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.093"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(2..1807)
                     /gene="glmS"
                     /locus_tag="KB902_001894"
     CDS             complement(2..1807)
                     /gene="glmS"
                     /locus_tag="KB902_001894"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBB6808715.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            2217..2507
                     /locus_tag="KB902_001895"
     CDS             2217..2507
                     /locus_tag="KB902_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808716.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            2520..3545
                     /gene="sppA"
                     /locus_tag="KB902_001896"
     CDS             2520..3545
                     /gene="sppA"
                     /locus_tag="KB902_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBB6808717.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            3548..4207
                     /locus_tag="KB902_001897"
     CDS             3548..4207
                     /locus_tag="KB902_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6808718.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            4364..5296
                     /locus_tag="KB902_001898"
     CDS             4364..5296
                     /locus_tag="KB902_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808719.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            5450..6739
                     /locus_tag="KB902_001899"
     CDS             5450..6739
                     /locus_tag="KB902_001899"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBB6808720.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            6986..8236
                     /gene="clpX"
                     /locus_tag="KB902_001900"
     CDS             6986..8236
                     /gene="clpX"
                     /locus_tag="KB902_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBB6808721.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            8319..8906
                     /locus_tag="KB902_001901"
     CDS             8319..8906
                     /locus_tag="KB902_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBB6808722.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(8980..9135)
                     /locus_tag="KB902_001902"
     CDS             complement(8980..9135)
                     /locus_tag="KB902_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808723.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            9271..10599
                     /locus_tag="KB902_001903"
     CDS             9271..10599
                     /locus_tag="KB902_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808724.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGILNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            10610..10819
                     /locus_tag="KB902_001904"
     CDS             10610..10819
                     /locus_tag="KB902_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808725.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
BASE COUNT         3603 a         1867 c         2243 g         3125 t
ORIGIN      
        1 attattctac tgtcactgat ttcgctaaat tacgtggttt gtcaacgtcg aatccccgta
       61 atagcgttgc gtaatatgca agtaattgag tcggtacgac tgtggttaga gtagttagat
      121 aagggtggac agttggtagc accagctggt cactttcctt ttctaatccc tctgagacaa
      181 taactagtgt tttagcgcca cggctttcga cttctttcag gtttcctcga gtatgcgcac
      241 cagtcacttc ttcactgatg attccaatca ctggtgttcc ttcttcgatc aaagcaatcg
      301 ttccatgttt caattcgcca gcggcaaaac cttctgcctg gatataactg atttctttca
      361 atttcaaagc agcttcaaga gaaacgttgt agtcagcgcc acgtccaatg taaaaggcat
      421 ttcttgtatc gctgagatat acttctgcca actcttctaa ataatctttt tgggcgatga
      481 ccgattccat cgcattagca actaaactca attcatgagt gatatcgaat acaagagaag
      541 tttcaaattc ttttttatca ccgatagctt tggctaataa agttagtaca gctatttgtg
      601 cagtataagc tttcgttgat gctactgcga tttcgggtcc agcatgcaat agcagtgtaa
      661 aggatgcttc ccgcgaaaga gtagaaccag caacatttgt aatcgtaagt gaagggtagc
      721 cgagacggtt gatttttacc agaacttggc ggctatctgc tgtttcgcca ctttgactca
      781 agaaaataaa gaatggtttt tttgaaagaa gaggtgtgtt atagccaaat tcactggcta
      841 aatgaacctc aacagggatc tgtgtcaatt tttccaaagt ctgtttacct gctaaccccg
      901 catggtaact agttccgcaa gcaacgatat agattcgatc gctatcagac aatgtatcga
      961 ccagcttttg atcaagagag acacgattgt cttctgttac gtatttttga gcgatacgac
     1021 gcatgataat aggctgttcg tcgatttctt tcagcatata aaaaggatag gtacctttct
     1081 cgatatctga agaatctact tgtgcttcga atgaagaacg ttctacgatg tcacctgcaa
     1141 aattttgaat aataactttt tctgatgtga cggtaaccat ctcttcatct tcaatctcaa
     1201 cgaattcctt cgtatgagca agcatagcca ttgcatcgct ggcaatcaca ttgaatccat
     1261 cgccgagtcc gattaatagt ggacttttat ttttagcgac gtaaataaca tcaggtgctg
     1321 tccgatcaat caaagcgaaa gcgtaagaac ctttgatgac ccgcaaagct tttaaaaacg
     1381 cctcttgcgt tgtagtatcc ttcgcgaaag tttcaattag atgagcgata atctcagtat
     1441 cggtctcacc aataaagtgg tcatttgcta aataagcaat tttaagttct tcaaagtttt
     1501 cgattacgcc attgtgaacg agcacgaagc gtccactttg ggaagtatgt ggatgggcgt
     1561 tttcttcaga aggttgcccg tgagttgccc agcgtgtatg accaatacct atatttcctg
     1621 tagtatcaat atttattttg tttttcaaat tttgaattct gccttgtgct ttgaccagat
     1681 aatcagttgt gccatctgag acaaagatac cagctgaatc ataaccacgg tattctaatt
     1741 tttctagacc gtcaatcaat cctggtgtta cattttttaa tccaatcatt ccaacaattc
     1801 cgcacataaa aaacatccta ctttctataa tgaattcgta tgaatgcttc cagctgcagg
     1861 aaaatccttt tgttttatct ttgcagatat tttttgtgga ttttctgtag agtgcagtcc
     1921 ctagggccat ccgccgaatc tttcgataaa ccctctcctc gtcatctgtt tacacagacc
     1981 tggcgctatc ctaaaaggta taactatcct cctcttttgt tttttatctg gaaacattta
     2041 aaatcataac cttttgcgaa tgttcttgtc aacaaaaaaa gaataaaaaa taaattggta
     2101 tatatcaaat gctttgtcaa atgctctttt tatgtcaaaa aataatgggt ttttatctat
     2161 catctttttc aggagttcgg tacaatagaa agtaatcgga tagaggagga gtaaaaatgg
     2221 attcaaaaat tgagatcatg acactgggaa tgttaaaaaa acaattgtcc aaattcgaag
     2281 catcagctgg tgtatcagat gatacgaaaa tatttttaga tactggctgg gatagcatcc
     2341 aagaaatcgc acctgatgcc ttggaagttg ctgaagctcg tgagtttacg gtagaagatg
     2401 aattgacaaa agagtcgttt tccgggtatg cgcgggaaga aaaagcagag cggttcgaca
     2461 cttctgagca gtcagaaact gtgatcgtca taaaaaactt gtattagaaa ggagaaagaa
     2521 tgaataagag acgttgggca gcagttctga ttgctgcagg attatttgtg gtttcgttag
     2581 tttcagctag tttgactaag cctcaggaaa acgatcaaat tgagggattg aacagttggt
     2641 tatatgggga tgaagaacta gcttcaaatg tgttggaaga gggagacagt acgcaaaaaa
     2701 tcgtaaaatt atcagtagat ggaacgattg ctgcgggagg gtcttcaggt ttatttgctt
     2761 ctgaaggtta caatcataaa aattttatgg aacaactgaa ggcgattgaa gaagatccaa
     2821 cagtcaaagg tatcttttta gaagtaaatt ctcctggtgg cggtgtctac gaaagtgcgg
     2881 aaatcgctaa gaaattggat acgattcgta aagaacatga tatcccaatg tatgtcagca
     2941 tgaaaaacat ggcagctagc ggtggctact atatttctgc tcaagcagat aaaatctttg
     3001 caacagaaga aacagtgacc ggctcaattg gtgtgatcat gtcaggattg aattattcag
     3061 gacttctaga aaaactgggt gtggaagata caacagttaa aagcggagcg ttgaaagata
     3121 tgggttcagg aacgcgacca gagacaaaag aagaagaagc ggtgcttcaa gcatatatcg
     3181 acagcgcata tagtcgtttt gtagcaatcg tcagcgaggg acggaataaa tctgaagaag
     3241 aagtcaaaaa aattgctgat ggaaggattt atgatggtgt ccaagcaaaa gaagtaggtt
     3301 tagtcgatga attgggattt cctgaagatg ctttaaaagc tatgcgaaag gaacaacagc
     3361 ttgaagatgc ggaactagta gaatattctt ccacgccatc tgggtttgct agtacatggt
     3421 taggaagtaa actagcagaa ttccagggat tgaagccttc tgagactagt cagatcttat
     3481 ccgttcttga gaatctaggg acagcggaat caccaaaagc aatgtattat tacggaggtg
     3541 agtaagcatg tcagagcttt caaatgaaaa taaggaacaa gaaaaagata agcaacagca
     3601 gcctgctgta ggacctgact ccaacttttc ccaaaaggta ctgagctctt ttgaaagaga
     3661 gcctttgacg cccgaagaaa tcaaaaagaa acaacgtaaa tggaaaaagt atacggacac
     3721 aagaaatgaa ccgccaaaag caaatgattt tcctaagtat ttctatgcag gtttttttat
     3781 ccgaatgttt gctttcttgg tcgatctttt gtgtatcgga gctattacgc gtttaacact
     3841 tggtattgcc aaaaatctag gttggcttaa tttttcagat tcttatctga gtatctacgg
     3901 attcacagcc ttacttattt atctagcgta ttttatttta ttgacgaaat tcaatcatgg
     3961 tcaaacgatt gggaaaatga tctttggtat tcgagtcatc agctttgatg aagaagaact
     4021 tagctggtca accgttttag ttagagaagg tgcttgccgg ttcattctaa aatttccttt
     4081 gctgatgtta gggtatcttc cagcaatctt taatcagaaa aagcaacatc taggcgattt
     4141 tttcactaat acaagtgttg ttacgatcaa tctgatcaaa gcattcaacc aggaagtcaa
     4201 cagctgatga gcaataaaaa gcagtaacag ttgaaagcac cttctaaaag tcagatctaa
     4261 aatctagctt ttagaggatg cttcagttat ttttaattgt catgcttttt ttgttttgct
     4321 actattgaac atgagctgaa catgagcaag aggaggacac tgcgtgaagc cgattgattt
     4381 tccagaaaaa tatgagaatt taatgcgagt agcacaacaa gcactagcaa accagcaata
     4441 tcagcaggca aaagaattat ttcaacgagc ttacgagttg aaagaaagct ttgaggctaa
     4501 tagcctgctt gttttttgtc tttacgagtt ggacgagaaa aaagaagcat tgaagcaagc
     4561 actcttgcat gaaaaacagt atcttcaaaa tgaggagttt gctgaatttt attttgactt
     4621 gttaatcagt acacaagatt ttttatatgc tagaaaattg atagcaagta cagattttta
     4681 tgaagctttc gagcagcggg tcattgaaaa aatccaattt gcagaagaat tatccggaca
     4741 aatggagagg cagaagatca aggcactcca caataaatcg gaggaacttc cttcgttgga
     4801 acctgcacgt cagcttgcgt ctattgatga gatcgaacag cttccttatc atgagtttat
     4861 ccaaacagcg agtaaactta ttgtatcgcc agaggtccat attttagcaa gggcaaaatt
     4921 actggagaca cttaggcaat tgaacgaatg ccatcctgtt ttctatttga cgattgaaga
     4981 aaagttagtc aaagtcatac caaaagatct gccaaagccg cagcagcagg caagttacca
     5041 gcaattatgt gtattttcag atcgttacgg taatgaagat gcgctgctta gttccgtgtt
     5101 aaatgaagaa ttcacgttgc aatctgcaat tgtttatcct gtctatgata catacatcga
     5161 agacccgaag cgctggtttc aactgactgt agaggcgtgt acaggaaaaa cgatgtatga
     5221 aggtacagaa gatgaaaaac aagatttttt aaaaaaaaga gaaaaaattt tgcagcaaat
     5281 gatcttcttc cattagattt tatcagtgaa aaagataaaa atgttatgaa aaacaaggat
     5341 tctatccatt caatatgttt acaatttgaa agggttagtg tactatttaa aggtatgcat
     5401 gaaacgtttt tgatgtataa aatgaatttc taaactcgga gggaattaaa tgactgcaac
     5461 atttgaaaaa aaaggcacga atgatggtgt tttaaaattt acgattgcgc aagacgaaat
     5521 ccaaaaagga ttaacaactg cgtttaataa agtgaaaaaa agcttgaacg tacctggatt
     5581 ccgtaaaggg aaagtttctc gtcaagtatt caaccgtatg tacggtgaag aagctttata
     5641 tgaagatgca ttgaatgctg tattaccaga agcttatgaa gctgctgtca aagaagctgg
     5701 catcgatcct gtttctcaac caaaaatcga tgttgaaagc atggaaaaag gtcaagactg
     5761 ggtaatcact gctgaagtaa cagtgaaacc agaagtaaaa ttaggacaat ataaagatct
     5821 agttgttgaa aaacaagacc gtgaagtaac agatgctgac gtggatgcac gtatcaaacg
     5881 tgaacaagaa gcacaagctg aattagttat caaagaagat gctgcagctg aaaatggcga
     5941 tacagtagta atcgacttcg aaggctttgt agatggcgaa gcgtttgatg gcggaaaagg
     6001 cgaaaattac tcacttgaat taggttcagg ctcattcatt ccaggttttg aagatcaatt
     6061 agttggtcat aaatcaggtg aaagtctaga tgtaaatgta actttcccag aagattatca
     6121 agcagaagat cttgctggaa aagaagcagt cttcaaagtg acaatccatg aagtaaaagc
     6181 aaaagaagtg cctgaattag atgacgaatt cgcaaaagat gttgatgacg aagtatcaac
     6241 attagacgaa ttgaaagaaa aatatcgcaa agaattagta gaaacaaaag aaaaagcagc
     6301 ggacgatgca aaagatgaag cagcgatccg tatggctgtt gaaaacgcag aaatcgttga
     6361 attgccacac gtgatggttc atgatgaagt acatcgttca atggacgaat tcttgaacaa
     6421 catgcaacgt caaggtatct ctcctgaaat gtactatcaa ttaactggtt ctacagaaga
     6481 agacttgcat aaacaattcg aaggtgaagc agaaatgcgc acaagaacaa atcttgtgat
     6541 cgaagcaatt gcagctgctg aaaatcttca agcaacagaa gaagaaatca atgcagaaat
     6601 ccaagaatta tcagaaacat acaacatgcc aatcgaacaa atcaaacgcg tgttgacaga
     6661 agatatgctg gaacatgatg tgacaatgaa aaaagcaatc gaattgatca caggtacagc
     6721 gacagaagcg aaagaataga aatcaagtaa taaatcattt ctgaagaagc tacttctaga
     6781 aaattgttta ttcgaaataa gggactgtga cacgattttg tcacagttcc ttattttttg
     6841 ttaagagtaa aaaatgcaaa ggtataggtc agttgatcct ttgttaaaca ctttttcttt
     6901 ttactaaact atgttatgat agtaaaagac tgtaaagtct ttgatagttt cttgcatact
     6961 ttttgcaagt taaggggtga agaccatgta tgacaatcca agtagcaatg agaccgtacg
     7021 ctgttctttt tgcgggaaaa cccaagaaga agtgaaaaag atcgtagctg gtccaggggt
     7081 ctacatctgt aatgaatgta tcgacctatg taaagaaatc attgatgaag aattttatga
     7141 agaagctgta cgcgaattca ctgaagtccc taaaccacta gaaattcttg aagtattgaa
     7201 taactacgtg attggacaag atcgcgcaaa acgctcgtta gctgttgccg tatacaatca
     7261 ctataaacgt gtcaatcagc aagcacaaga aaacacagat gatgttgaac tgcaaaaaag
     7321 caatatctgc ttgatcggac ctacagggtc tggtaaaaca tttttagcac aaacattagc
     7381 aaaaacattg aatgtacctt ttgcaatcgc agatgcgaca agtttgacag aagctggtta
     7441 tgtgggggaa gatgtagaaa acattttgct taaattgctt caatctgctg attacaatgt
     7501 ggaacttgca gaaaaaggga tcatctatat tgatgagatc gataaaattg cgcgtaaaag
     7561 cgaaaatgta tctattactc gtgacgtttc cggcgaaggt gtccaacaag ccttgctgaa
     7621 aattctagaa ggaactgttg caagtgtgcc acctcagggc ggacgtaaac atccacatca
     7681 agaatttatt cagattgata cgacgaacat attgttcatc gtaggtggtg catttgatgg
     7741 catcgaaacg attgtgaaga atcgtatggg cgaaaagacg attggatttg gtacacaaaa
     7801 ccaaaaactt tctgaagacg aaagtgtcat gcagcatatc attcctgaag atttactaaa
     7861 attcggattg atccctgagt ttatcggacg attacctgtt atggcagctt tagagaaatt
     7921 gacaacagat gatctggtac ggatcttgac tgagccgaaa aatgcgctag tcaaacaata
     7981 tcaaaaactt ctttctctag ataataccga acttgaattc gaacctgaag cgttgagagc
     8041 cattgcgaaa aaagcaatcg aacgcaatac cggtgctcga ggacttcgtt ccatcattga
     8101 agaaatcatg atggatgtga tgtttgatat cccttcaaat gaaaacatcg aaaaagtgat
     8161 tatcacaaaa gaagcagctg aattgtctgg tgagccaaca gtaatctata aagattcaga
     8221 gaaaaaagcg ggttgatgaa aagaggctgc cgtaaaagtc attttggctt ttgcgacagc
     8281 cgcttgcttt attcatcacc ttgttaagga gagagaccat gaaagtccat caagctgaaa
     8341 ttatcataag tgcagtggca ccaaaacaat atccagatac acaattgcca gaaatagctc
     8401 tggcaggacg atcaaatgta gggaaatctt cttttatcaa cacattgatt gatcgaaaga
     8461 atttagcccg tacttccggt aagccaggaa agacccagac attgaatttt tatttgatcg
     8521 agaacgcatt acattttgtc gatgttccgg gatatgggta tgcaaaagta tccaaaactg
     8581 agcgagcaaa atggggaaag atgatcgaga catatttaac gactagagac cagctacgtg
     8641 cggtcgtttc tttagtagat ttgcgtcata agccttctca agaagatatc cagatgtatc
     8701 aatttttgaa gtattatgat atccctgtaa ttgttgttgc cactaaggca gataagatcc
     8761 ctcgtggtaa atggaacaag catgagagcg aaatcaaaaa agcgttggat tttgatcgca
     8821 atgacacgtt tattctcttt tcttccgtta caaaacaggg aaaagaagaa gcgtgggcag
     8881 caatcgaaca agcaattgaa tcataaaaag aataaaaaag acttaccagt caaactcttt
     8941 cataaaagtt tggctggtaa gtcttttttt gagcttaact tacttttgtt tcttgtcttt
     9001 tttcttttca ttttgtggct gtggttttag aaatcgatcg atctcttctt ttggtgcaac
     9061 tgttttttcc ggatcgacag caaatgattc gaaaagttta tctaaattat ctgtacgttc
     9121 aaatttcaac cccattgtaa acacctcttt gtttcttttt acttagtcta tcatgtaatc
     9181 gtccaaattg gtttctaaga cataaagttt tagtttttct ttatcattgg ttataattaa
     9241 attataaaaa gatttgaaag aggtgagaaa atgattggcg aagataaatt attgatgact
     9301 atccagctca cagacttaaa tgaagaagaa aaaaaacagg aaataagcga ttgggctatt
     9361 ttgacacgtc tgttgatcca gccaacattt atccgctctt tcacacaaca agcggatccg
     9421 tatgatcttc gaaagcttca agaaaaaata atgctagcat cggtaagaga cgaaagttgg
     9481 ttagttgtag gaaatgacga gaacgaatgt agttttcgct tggaagataa tcaattattg
     9541 ataaaaaatg tattgtctat ctctgttttc aaagaaaagc aatttttgat tcgagacttc
     9601 attcagaaaa aaatgattgc tcatggggtg ttcgcctata tgcgagctta tagcgagttt
     9661 atctatcaca atacaaaaca gatctctcaa cggctattgt ttgagaaaaa ggatgaaatc
     9721 gaacatttac ctaaaatgaa acaacaaaac ggggaagtag tagtcgattg caaccaattt
     9781 ccaggatacg atctttttta ccaaggttta tgtttcactt cgtgttggga aatgtattat
     9841 agtcgctatt atcatcaaat catccctaaa ccgatttttc tcgacatcca acaagtagaa
     9901 aaagtgaagg aattagaaaa cgaagtcata tgtatccagc tttatcgaga cccctttaac
     9961 tggcaaaagc caaacaatca aatgtttcaa tcctatttta gggaccagct tgggtttgat
    10021 catcttgctt gggacaatgg tgtcggttta ttgaaaccgc cattcgttga atacatttac
    10081 actgaccata cgatccaatc tgtccagtat cagaatgcac aaatgcaacc tgttcctaaa
    10141 aagaatgctt cattttttgt aacaaaaagt tatgatattc aacaaggaga ttataaagaa
    10201 aggcgtgttc gcggaatact aaatgctcag gcgtattttc cttgggttga cgagaatcgc
    10261 tcgcgcatga tgtgctataa agttatcgat ccgactgttg ctttggataa tggaatcgaa
    10321 gcttattgtt attatattag ggaatatcta gaagtagagg taacagatga aaaatatcaa
    10381 gagtatcttt tatccttaag aatctatgtt ccttcagaat ccctgtcaga attaccgtta
    10441 aaggaaatca aacatagact ctctgatgtt accttcaaac gaataaagaa aaagcggcga
    10501 agtatccaat tcgatgtcaa gaaaggtgag cagcatctgc gtgtgcaatt tttagattac
    10561 cgagaattag aacaattgat tactttacaa aaaatatgag gtgaagaaaa tggataaaca
    10621 actctattat cgaataatgg ttccggcatc attattatcc gtctgtctct tttttgttcc
    10681 taattttcct attcgatcag tcatcggttt tttggtcatg tttggcggga tgggacttta
    10741 ttattatctt cttcataagg aaagaaaacc tgcttctgtt tatatgaaaa aaacaagaag
    10801 cgaaaataaa aaacgataaa acggcttgat gatagaca
//
LOCUS       DADVXB010000092        10622 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.094, whole genome shotgun sequence.
ACCESSION   DADVXB010000092 DADVXB010000000
VERSION     DADVXB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.094"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(71..397)
                     /locus_tag="KB902_001905"
     CDS             complement(71..397)
                     /locus_tag="KB902_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808726.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(770..1971)
                     /locus_tag="KB902_001906"
                     /pseudo
     CDS             complement(770..1971)
                     /locus_tag="KB902_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            2088..2603
                     /locus_tag="KB902_001907"
     CDS             2088..2603
                     /locus_tag="KB902_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6808727.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2802..3248)
                     /locus_tag="KB902_001908"
     CDS             complement(2802..3248)
                     /locus_tag="KB902_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6808728.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3295..4773)
                     /gene="msr(C)"
                     /locus_tag="KB902_001909"
     CDS             complement(3295..4773)
                     /gene="msr(C)"
                     /locus_tag="KB902_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6808729.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(5127..5756)
                     /locus_tag="KB902_001910"
     CDS             complement(5127..5756)
                     /locus_tag="KB902_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6808730.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEVKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(5740..6204)
                     /locus_tag="KB902_001911"
     CDS             complement(5740..6204)
                     /locus_tag="KB902_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6808731.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(6691..7959)
                     /locus_tag="KB902_001912"
     CDS             complement(6691..7959)
                     /locus_tag="KB902_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6808732.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(8190..8927)
                     /locus_tag="KB902_001913"
     CDS             complement(8190..8927)
                     /locus_tag="KB902_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6808733.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYSDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8994..9563)
                     /locus_tag="KB902_001914"
     CDS             complement(8994..9563)
                     /locus_tag="KB902_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6808734.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            9741..10562
                     /locus_tag="KB902_001915"
     CDS             9741..10562
                     /locus_tag="KB902_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6808735.1"
                     /translation="MSRAAKSLHITQPTLSKQLKDLEEELGVTLFTRGSREIQLTDSG
                     RYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAISFISDSLHSLIKAHPDI
                     QFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLPAQDRWGLLIHRNHPLAK
                     QTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVGTYNLLYNASLMVDNGTF
                     GALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSPAARKFLDVLTEKYS"
BASE COUNT         3153 a         2232 c         1855 g         3382 t
ORIGIN      
        1 ctgccggact ttttagaggc tgtgacaaag attttgtcac agcctctttt tccatataaa
       61 cggcgttcgc ctaccagctg cctggtaaat ctgtttcctc ttcgttaaga agcgaaaatc
      121 cgtcaaatgt ttcgccatca taataacgaa gcagctcatc catggacaag ttcatcgttt
      181 tttctttttc ttcttccgct gattcagcca gtagctgttc ccgatacacc tgatacatac
      241 cagctatttt ttgctgcatc gcttttctag tttcaccttc cgcattgatt attggcaatt
      301 ctttgatata gccacgataa atcaaccgat catctgaaaa ttcaatgggt aattcaacga
      361 gtgtcaaccc gacttcctga aaatattctt ccagcatcta ttatcccccc attctttttc
      421 ttaaatgaat tttagcttac ctactgaaaa ttttccagtt tcattatttt gagaaaaaaa
      481 gggaatgtga caaaaatcgt gtcacatccc ctttttccga ataaatggtg ttcttctgcc
      541 aactcctcaa tcataagtca caatattcaa caaacatgag aaactgtttt ttgaaattgt
      601 tccttgtgat tcagagttaa acgacagtct cacaacctct tggtaaacgg cgttcaaaag
      661 cttgcatctg cggtaataag cccaaccaaa cgaaaaatat gagaagctat ttttgtttgg
      721 ctgttcttat gacttgatgc aggacagctt tttcacaacc tctgatttct tattcttctt
      781 catttgtagc aaaataatta cggtgataaa tgatacaaca tacactgata agaacaatgg
      841 cacctgcaaa ataaaacgca tagctttcac caatatgttc accaatcaca cctgcaataa
      901 atggtgctaa agctccaccg aaaaagcgga caaaactata gctggacgaa gcaacgtttc
      961 gttgcagacc tggtatttcc atagcaatcg tcgtcaacag tgtattgata attccttgga
     1021 aaaatcctgc taacacaatg ctgatcggta caaggactgg catagaagtt ccagctccta
     1081 ataacagcaa acaaataatg aataagacaa atgctgctaa aattgtccga taagtcgtaa
     1141 acttccgctc aagagccggt gcaacgaaaa tcgaagcaat agccagaagc acaccccagc
     1201 caaaaaatac aaaaccgact tctaattcag aatagccaat caataaaaat ggcgcatacg
     1261 caagtaaagt aaagaatccg aaattatata acaatgcgat tagtccaact gaacgaagtt
     1321 tatgattgct taacgctttg acaccttccc aaaggcctac ttttctcttt ggtttctcag
     1381 tttcaggtaa aagtaccgct agggctataa aaccgcaaaa catcaaaaat gctaccccaa
     1441 aaaatggata acgccatgaa ccactgccca agaccccacc gactagaggg ccaacagcca
     1501 ttccgcagcc aagtgctgct tcatacatca tgattgcttt ttctgtgtta ccaactaaaa
     1561 tactgacgat cgttgctaaa gcagtagaga caaataaagc attcccgaca ccccagccgg
     1621 cacgtaaccc aatcagcatt ccgatattcc cagataatcc gccaagacca gcgaatacaa
     1681 cgatgataaa caatcctgtc atcaatgttt tttcaaaccg atccgactag ataagaaacc
     1741 tgtaaatagc atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc
     1801 agctggcgta gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac
     1861 tcccataaaa gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt
     1921 ttcttcattt gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc
     1981 tctattagca tcatacatga tttattttac atgtaaatat gcacatgtaa aacgtggaaa
     2041 ctttactgtg atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag
     2101 cctatatatt attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc
     2161 tgatcacaat tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag
     2221 accagcaggg ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc
     2281 acttgactga tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc
     2341 ctacgcaaaa agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa
     2401 cagctactgg actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc
     2461 aaaaaaaatt gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga
     2521 tccagcgcag aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac
     2581 aaatgcagca gttttttgag taagggataa acagaacctt tctagaaata tctattgaag
     2641 agcaaattat cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac
     2701 aggccaaaac ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac
     2761 aaaaagcatg ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt
     2821 gcttttagca cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca
     2881 atcacattca ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt
     2941 tccatgatca caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa
     3001 atagttaaga tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt
     3061 ttcgccagca caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact
     3121 agaccaatca acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc
     3181 atccccaaga ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt
     3241 gtaggcaatc tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa
     3301 atttctcgta agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt
     3361 acgctcgaca aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat
     3421 tagcttctct aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag
     3481 caacacatta cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc
     3541 acttaatgta cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa
     3601 actacggaca agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc
     3661 ttcagatgtc atttgataac ccttttgctg atatacttga aagcttactt tcggagagag
     3721 aaggattcct tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt
     3781 ttcaccgaca atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa
     3841 tgttctccca cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag
     3901 ttcaagagat tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc
     3961 tcctattttt tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac
     4021 actgtctttt tgtttagagg aagacaaccg atccggtctg atttgttgct ttttcttttt
     4081 actggacact ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa
     4141 tcgttttttc tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc
     4201 cttttgagtg agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac
     4261 ttcccagatt ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag
     4321 cgtaccataa taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg
     4381 ggttgttggc tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc
     4441 gatctttcgt tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg
     4501 gaaatgactg gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg
     4561 caggtagttg aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc
     4621 tattagtttg agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc
     4681 ttgctgatag acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg
     4741 tagatttgtt atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa
     4801 acaacaatta tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac
     4861 atcttttcct actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc
     4921 acctattcta ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata
     4981 catgtctttt gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc
     5041 agtcattttt ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata
     5101 gctactgaat agtaactgaa aaccttttat tcgaacgtag tgatcttttc tggtgctaaa
     5161 cgaacagact cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca
     5221 taacggtctt tatccaaacc aaatgcctct gccaactgat ctgcttcgaa tccaccaatt
     5281 ggatttgttt catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta
     5341 gaatcgactt tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg
     5401 atcgcagcta attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg
     5461 ttatagattt cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca
     5521 gaagaagtat cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttact
     5581 tcctcgcttt cagcgaccac aaagcgccat ggttgcatat tgacagaaga aggtgcagtc
     5641 gtcgcttctt tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat
     5701 acgcgaacgg atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt
     5761 attaacctct ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag
     5821 tgttagaaat tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc
     5881 tttatggtcc atttcacaat gctcgatttt cttctgggct ttttctgtta gcgctacata
     5941 cacttcccgg ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac
     6001 cttcagatga cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg
     6061 tagcaatgga ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc
     6121 gatattttct tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag
     6181 gtgactaatc tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat
     6241 tgacttgtca ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa
     6301 aaaacgctct caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa
     6361 atgataaaga aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga
     6421 tagctcttct gcagtagaaa attttacacc gccaaaaatt tccgaaatcg ccttttgcaa
     6481 gaatcccgtc gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg
     6541 acaagatgtt gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta
     6601 ataagttcaa ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt
     6661 gatgcagggc agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata
     6721 tctccagccc atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt
     6781 accagttttt tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa
     6841 acttagacct tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat
     6901 tgtgtaatga tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt
     6961 tggtgcttgc caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc
     7021 tccggcattc aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg
     7081 agaagttgaa gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt
     7141 caatgtagaa ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc
     7201 tttgtaagag ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa
     7261 agaagtcgtc ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt
     7321 tctaaaagcg gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt
     7381 aacagattgg ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc
     7441 caaagtactg ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata
     7501 taagtcattg gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg
     7561 ttgagaatta gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga
     7621 caaatctgct tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc
     7681 ttctgcattc tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg
     7741 ttctgttgtt tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga
     7801 ctgcaaagta ctctctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt
     7861 tgcgacagtt tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc
     7921 taaaagaata acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat
     7981 gaaacttttc ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt
     8041 aaataacatt tgtttctttt tgataaattt gctttttcta cataaaaaga cgtaaatgaa
     8101 gaatattctt ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt
     8161 aattctcttt ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc
     8221 atgttactga cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata
     8281 tcttcggagg tcaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg
     8341 tcgctgatgg tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg
     8401 atgttatttt gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt
     8461 gttccgcaat aaacggcgga atcagaataa acaacatgtc ccgccacaga atcagttgaa
     8521 atgatatgcc cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac
     8581 acacccatga tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat
     8641 ggagcggttg gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc
     8701 atcgctaaat cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata
     8761 tatagctcag cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca
     8821 gctataacta gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg
     8881 cttgaagcgc ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc
     8941 tgttttgaaa aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata
     9001 atccgttcga caggtttgac gattttggca gggattcctg caacgatggt attgtctggg
     9061 acatctttcg taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct
     9121 ggcagaatag ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact
     9181 gacaagcctc ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga
     9241 ggaccaatca atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga
     9301 cgattgataa agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc
     9361 agcagaacag tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg
     9421 atatctgctg gttcatggta cccagtattc agcgctgcta aaggctcttc gttttcagct
     9481 tggatctgat ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt
     9541 tgtttttcga tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg
     9601 gcttatcatg tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg
     9661 gtatgctttt ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttag
     9721 cagtagctag aaaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta
     9781 ctctctcaaa acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcggg
     9841 gctcccgaga gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa
     9901 tcttgtcgtt ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag
     9961 aaatctacat tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt
    10021 cgttgatcaa ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata
    10081 tcatagacaa actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca
    10141 aacaaaaata ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc
    10201 gaaatcatcc tttagcaaag caaaccgtca tccatccgca ggaactgaaa actgttcctt
    10261 tgatcatttc ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca
    10321 tagatcagtt atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg
    10381 ataacgggac ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa
    10441 aaatattcat cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag
    10501 accagcctct ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt
    10561 aagtagagtt tttttccttc gctttcagct ttttaacaac gaataagata agcaaaagat
    10621 cc
//
LOCUS       DADVXB010000093        10574 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.095, whole genome shotgun sequence.
ACCESSION   DADVXB010000093 DADVXB010000000
VERSION     DADVXB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.095"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            12..84
                     /locus_tag="KB902_001916"
     tRNA            12..84
                     /locus_tag="KB902_001916"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="KB902_001917"
     tRNA            88..160
                     /locus_tag="KB902_001917"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="KB902_001918"
     tRNA            168..249
                     /locus_tag="KB902_001918"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="KB902_001919"
     tRNA            267..339
                     /locus_tag="KB902_001919"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="KB902_001920"
     tRNA            351..422
                     /locus_tag="KB902_001920"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="KB902_001921"
     tRNA            439..524
                     /locus_tag="KB902_001921"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="KB902_001922"
     tRNA            535..608
                     /locus_tag="KB902_001922"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="KB902_001923"
     tRNA            618..691
                     /locus_tag="KB902_001923"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="KB902_001924"
     tRNA            711..783
                     /locus_tag="KB902_001924"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="KB902_001925"
     tRNA            811..884
                     /locus_tag="KB902_001925"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="KB902_001926"
     tRNA            898..971
                     /locus_tag="KB902_001926"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="KB902_001927"
     tRNA            995..1084
                     /locus_tag="KB902_001927"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="KB902_001928"
     tRNA            1097..1170
                     /locus_tag="KB902_001928"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="KB902_001929"
     tRNA            1189..1264
                     /locus_tag="KB902_001929"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="KB902_001930"
     tRNA            1266..1336
                     /locus_tag="KB902_001930"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="KB902_001931"
     tRNA            1350..1423
                     /locus_tag="KB902_001931"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="KB902_001932"
     tRNA            1448..1535
                     /locus_tag="KB902_001932"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="KB902_001933"
     tRNA            1557..1628
                     /locus_tag="KB902_001933"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="KB902_001934"
     tRNA            1651..1740
                     /locus_tag="KB902_001934"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="KB902_001935"
     tRNA            1753..1826
                     /locus_tag="KB902_001935"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="KB902_001936"
     tRNA            1845..1917
                     /locus_tag="KB902_001936"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="KB902_001937"
     tRNA            1921..1993
                     /locus_tag="KB902_001937"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="KB902_001938"
     tRNA            1998..2068
                     /locus_tag="KB902_001938"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="KB902_001939"
     tRNA            2081..2154
                     /locus_tag="KB902_001939"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="KB902_001940"
     tRNA            2166..2237
                     /locus_tag="KB902_001940"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="KB902_001941"
     CDS             2503..3696
                     /locus_tag="KB902_001941"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBB6808736.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="KB902_001942"
     CDS             3826..5298
                     /locus_tag="KB902_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6808737.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="KB902_001943"
     CDS             5381..6169
                     /locus_tag="KB902_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBB6808738.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="KB902_001944"
     CDS             complement(6236..6904)
                     /locus_tag="KB902_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBB6808739.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="KB902_001945"
     CDS             7019..8731
                     /locus_tag="KB902_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808740.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="KB902_001946"
     CDS             8734..10506
                     /locus_tag="KB902_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808741.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         3033 a         1926 c         2453 g         3162 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggca
//
LOCUS       DADVXB010000094        10512 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.096, whole genome shotgun sequence.
ACCESSION   DADVXB010000094 DADVXB010000000
VERSION     DADVXB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.096"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(187..672)
                     /locus_tag="KB902_001947"
     CDS             complement(187..672)
                     /locus_tag="KB902_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBB6808742.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    762..1107
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1152..1793
                     /locus_tag="KB902_001948"
     CDS             1152..1793
                     /locus_tag="KB902_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6808743.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1812..2447
                     /locus_tag="KB902_001949"
     CDS             1812..2447
                     /locus_tag="KB902_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6808744.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2465..3280
                     /locus_tag="KB902_001950"
     CDS             2465..3280
                     /locus_tag="KB902_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6808745.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3599..5035
                     /locus_tag="KB902_001951"
     CDS             3599..5035
                     /locus_tag="KB902_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6808746.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5224..7671
                     /locus_tag="KB902_001952"
     CDS             5224..7671
                     /locus_tag="KB902_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6808747.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7901..8968
                     /gene="rlmN"
                     /locus_tag="KB902_001953"
     CDS             7901..8968
                     /gene="rlmN"
                     /locus_tag="KB902_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6808748.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9161..10264)
                     /locus_tag="KB902_001954"
     CDS             complement(9161..10264)
                     /locus_tag="KB902_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6808749.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         3461 a         1802 c         2284 g         2965 t
ORIGIN      
        1 atatgcttct tttttcgtag aatcaataaa tatggatttg gctaactatg gaagaatact
       61 cgtattagtt ttcagcgttc atactagttg ttacattgtt tgattggcca aaagaatttc
      121 tgatatattt tgtgctaaat aaagaaaaag acgcttgaat tgggaaataa gaaaactact
      181 ctatcattac aaattttcat aaactggcag atgttctaag taaacaagta tcttttcaaa
      241 gtcggaaaaa tccataatca acgtagtggt attgatattt ggatgaaagc ctacggtatc
      301 ttgacgatca atagcagcat cgatcacgac ttggattttt ttctctttgt cgtgcatcaa
      361 tgctaatgga gtcactgtac ctgctggaac gcctaggagg tcaggaagct gttcttcaga
      421 aacaaaagat aagcgctttt cttttaattg ttcagctagt tgttttaaat cggcgtgctt
      481 ttcatcaggc aagatgacaa gatagatttg ttttcctttt cttgatttca ataatagatt
      541 ttttacttgc ggaccaggta gggaaaaagg gacatttttg actgacgtaa tcgcaggatg
      601 atcgactttt tgaaaagaga tacccagttt ttttagtagt tcataagctt cttgttcggt
      661 tgcacgactc atcgcgcatc accctccttt ttttattagt gtatcataaa aaagagttga
      721 caaatgaaaa ataatcatgt aaattacacg taaagttaaa acaaatgaca tcgaaaagaa
      781 gagtagccgt taggtgtttt tagagagtct ctggttggtg gaaagaggca gcagttaacc
      841 gtgaaacaca tcttggagtc gattttctga agcgtatagt aggaaaatcc ggggagcccg
      901 ttacagctgc ggtcgttgct agatgaccag ataaggctgg cttttccgtg aggagtcggt
      961 aaaaaaaggt ggaaccacgt gattaacgtc ctttgatctt cggatcaaag gactttttgt
     1021 tttcatctga acggcaacga ctgtgtgagg ttttttctgc aaggaaaaaa taaacagagg
     1081 tggaaccacg tataatacgt cctcttggca tttgccaaga ggattttttt attttaaagg
     1141 aggaaaagaa gatggagtat ttgattgaag ttatgccgca attattagta ggagcactca
     1201 caacattgaa attattttta tttaccttga ttggctcatt accattaggg attgttttag
     1261 cattaggatt gtctttgcat tttaagccgc tacgctactt gcttcaaaca tatgtatggg
     1321 ttatgcgggg aacaccgctg ttgttgcaac tgatttttat tttttatggg ttgccgacga
     1381 ttgggatcgt ttttgatcgt ttcgaagcag cactcattgc ctttatctta aactatgcag
     1441 cttattttgc agagatcttt cgtggaggga tacaatcgat tcctcaaggt caatatgaag
     1501 cagcgcaagt tttgcaatta agtccctttc aaacggtgac gaaaatcgtc atcccacaag
     1561 tgacaaagat tgttttacct tctgtaggga atgaagttat caacttggtc aaagattctt
     1621 ccttgatcta tatattaggt ttaggtgacg taatgcgtgc tgggaaaatc gcgatggaac
     1681 gcgacgcgac tttactgcct ttgctaggcg tggcaatcat ctatcttaca ttgactggta
     1741 ttctaacaat cgtaatgaaa caagttgaag gaaaattaaa ttattaccgc taactgatag
     1801 gaggaagaaa tatgattgaa ttgaagaaag tgaacaaagc atttggtgaa aaaaaaataa
     1861 tcaaagattt gaatctaatc attccagatg ggaaaacatt agctatcgta ggtccttccg
     1921 gtggcggtaa aaccacgctt ttacgtatct tggctggctt agaaagttct gacagcggag
     1981 aattttattt agacggtgta ccgttcaacc cattcgagct taaaatgaaa gaacaagttg
     2041 taggagtcgt attccaagac ttccagctat ttccacatct gaatattttt gaaaacatta
     2101 ccttagcacc aaaaatggta ttgaaacaga caaaagaaga atacaccaaa aaagcagaag
     2161 aattagcggc ttcattaggg attagtgatt tattgaatat ctatccttat cagctttctg
     2221 gcggacaaaa acagcgggta gcgattgcca gagcattggc tatgaatcca cgggtattgg
     2281 cttatgatga accaacaagt gctttagatc ctgaattacg ccagcaagtc gagcgtttga
     2341 tcctatcatt gaaagaagat ggggtaaccc aaattattgt cacccatgat ttagtatttg
     2401 cagaaaatgt cggtgatcaa ttactaaaag tttccccaat tcattaagaa aggagaagat
     2461 agagatgaaa aaaaccagtt ttctattcgc tttgatcgca ggtcttcttc tttttgcagg
     2521 ctgttcgaac aaaaaaactt cagcagataa ttgggcgact atcaacgaag agaaaaaaat
     2581 cgttataggt ttagacgata catttgttcc tatgggattt agagataaag acgggaagct
     2641 cacaggattt gatattgatt tagccaaagc agtctttgaa caatatggga ttacggtaga
     2701 ctttcagccc attgactggt caatgaagga atttgaactg aacaatggaa cgatcgattt
     2761 gatatggaac ggctattcca aaacgccggc aagagaaaag aaagtgcaat ttacaaaacc
     2821 ttatatggaa aacgatcaag tgctgatcac acctaaagaa tcaggaatca caaactttgg
     2881 acaaatgaat aataagagat taggtgcgca aaatgggtca tctggttatg atgtatttac
     2941 gaaacaacca gaagtattaa aagagatagt caaaaaccaa gatgctgttt tgtatgatag
     3001 ttttaatgaa gcattgatcg atctgaaaag cagacgggtc gatggtctgc tgatggataa
     3061 agtatacgca gactattatt tgaaacaaag aaacgaacta gaagacttca acataacaaa
     3121 aggttcttat gagagtgagg attttgcagt tggtgcacgc aagtcagata gtacattagt
     3181 gaaaaaaatc aatgaagccc tagatcaact agagaaaaca ggtgaattcc aaaaaatatc
     3241 cgataaatgg tttggcgaag atgttacgcc gagaaattaa caaatagggg actgtgacaa
     3301 aagacgtgtc acagtccctt tttccgaata aacagtgttc tcctgccaac tccttgtgac
     3361 tcggagctga atggcaggct cacaacctct tggtaaacgg tgttcaaaag ccagtttttc
     3421 ggtattaagc caaatttatg caaaaatgta gaaagccatt ttcacaaaat ttttcttact
     3481 actcgaaact aagcgacttt ttcacaacct cctttacata attttatttt gttgtggaag
     3541 gggtttcgtg ttattctaaa agaggaacga ttgaaggtta taggaaagga agagatgaat
     3601 ggaacacaaa gaacttacct catttccaaa agattttctg tggggctctg cttctgcagc
     3661 gtatcaagta gaaggagctt ggcaagaaga tgggaaagga gaatcagtct gggatcgatt
     3721 tgtacggata cctggaaaga catttaaagg aacgaacggt gatttggcag tagaccacta
     3781 tcatcgttat aaagaagata ttgctttaat gaaagaacaa ggtctgaaag cttaccgctt
     3841 ctctgtagct tggacacgga tttttcctaa tggacgagga gaagtcaatc aagctgggct
     3901 cgctttttat gagagattga tcgacgaatt gattgaaaac gatattgaac ctatgttgac
     3961 tttatatcat tgggatcttc cacaagcatt gcaagatgaa tataatggtt gggaatcacg
     4021 tcagatcatt gaagatttca ctcattatgc agaaacatta tttgaggcat tccgcgggaa
     4081 agtccattac tggattagtt tgaatgaaca aaatatcttc acttcattag gttatttgtt
     4141 agcagcacat ccgccaggtg tgacagaccc gaaacgaatg tatgaagtta accatattgc
     4201 taatttagca aatgcatctg tcatcaataa atttcacgag ttagaaatgc ctggaaaaat
     4261 cggaccaagc tttgcgtata cgccaaatta tccaattgac agtaatcctg aaaatgttct
     4321 ggctgctgaa aatgcagaag acctgatggc caattattgg atggatgtct atatgtgggg
     4381 aaaatatccg attgctgcca tgaggttctt agaagaaaaa ggatgggcac caacgattga
     4441 agctggcgat gcagaattgc tagaatctgc taaaccagat tttcttggga tcaattacta
     4501 tcaaacggcg acgaatgcat tcaatccatt aaacggagtt ggtgctggaa aaatgaatac
     4561 gacaggaaaa aaaggttcat cagaagaaac tggagttcct ggaatgtata aaaaagttga
     4621 gaatccattt gtcgaacgaa caaattggga ctgggagatt gacccagaag gattaaggat
     4681 cggactgcgt cgtatcacaa gccgttaccg catgccggta ctgattacgg aaaatggctt
     4741 aggagagtat gacaagttga cagaagataa acaaatccat gacgactatc gaatcaatta
     4801 cttacaaagc cacgtcaaag ccatcaaaga agcaatttcg gatggagcag aagtcctagg
     4861 ctattgcacc tggtcttata cagatttgct tagctggctg aacggttatc aaaagcgata
     4921 tggatttgta tatgttgatc aagacgaaac acaagaagga tctttggaac gatataagaa
     4981 agacagttat tactggtacc aaaaactgat tgaagaaaat ggagagaacc tttagttcac
     5041 atacttaaaa caagaaggta cggctggata tggccgtgcc ttttcttgat aaaatcattt
     5101 agaaattaag aaaaactgta aaataagctg aaaaatgaaa gaaagcgtca gttctttcaa
     5161 acaaaacttt agttccctta cttttttttg tataatgaaa cttgatgaaa tgagggataa
     5221 taaatggcac aaaagaaacg gcctactaaa aaaaggaaaa agacgaaaaa aacgaaaaag
     5281 caaaaacagc agcaggaaca aatgctgacg attggtgttg ggtttgcctt gattttattt
     5341 gctgtcttcg gctttttaaa attaggtttt ttaggaatat tgattgcaaa cggctttcgg
     5401 atcattgcag gaaatactta ccaaatcctc tgtcttttat tagccgtatt aggattttgg
     5461 attgtcatta agaatacaga gttttcaatt ggtaaaaacc gacgctggtt tggcggcata
     5521 ctcttttatt tcggtatctt attattgtta catgcccatt tatttggcaa actccatact
     5581 ggggaaccaa atatcatggg gacgacatgg gatttgttag ccagtgatat aaaacaaagt
     5641 caagtagaca ataacgttgg tggtgggatg attggagcaa tcctttatca ttttacttac
     5701 ttcttgattg cacagcctgg aagttattta gcagcagtgc tattactggc aggaggagca
     5761 ttcctgttca gtaatctgga aggctatcag ctgttaaatg gtatccaatc aattggagaa
     5821 cgagtacagg aattattgga aggtgatcct gccaagcaag ctcgaaagca agcggcaaag
     5881 gaagagagaa tgaaacagcg cgcagaagcg aaagaagcaa ggcgcttagc tgcaaaagaa
     5941 gctgcagaaa aagaagctgc agaatatgag aagaaaaaag cggtgagcca gcaaagggaa
     6001 aatactgctg atgaatggca ggaaccagaa aatacagagc cggagcagct aagttttgtt
     6061 ccaatcgaca gttttcaaga aaatatccat cctgcgaatc tagagaaacc agtaccagat
     6121 acaccaaaac agaccaatac agcagaaggt ttttcagatg agttgccaga ggatgacggt
     6181 acctcattag aatttgagat tgaagcagaa caggaaaatc aagactatga attaccgaca
     6241 gttgatttgc ttgattctat accaactgtg gatcaaagtg atgagtataa aaaaattgaa
     6301 aaaaatatcg gcgtattaga acaaactttc caaagtttcg gtgtcgatgc caaggtcgtc
     6361 aaagccagct taggaccatc cgtcacaaaa ttcgaagtcc agccggctgt aggggtaaaa
     6421 gtaagtaaaa ttgtgaactt aacagatgat atcgcgcttg ctttagcggc gaaagatgtc
     6481 cggatggaag caccgattcc aggtaaatca ctgattggta ttgaagtacc aaatggaaag
     6541 atcagtatgg tttcctttag agaaatcatc gaagcacaac caaaccaccc agataaatta
     6601 ctagaagtac ctttaggacg tgatgtttct ggacgggtac aaacggctga tctttcgaag
     6661 atgcctcact tactcgtggc tggttcgact ggtagtggga agtcagtagc aattaatggg
     6721 attatcacaa gtatattaat gcgtgctaag ccccatgaag taaaactgat gatgatcgat
     6781 ccgaaaatgg ttgaattgaa tatgtacaac ggcatacctc atctgttgac gccggtcgtg
     6841 acgaacccta gaaaagcagc gcaagcctta caaaaagtag tacaagaaat ggaagaacga
     6901 tatgaaaaat tcgcggcaac cggagtaaga aatatttctg gttacaatga atttgttcaa
     6961 cagaaaaact tggaaaacgg aacgaaacat ccaaccttac cattcatcgt agtgatcgta
     7021 gatgaattag ctgatttgat gatggtagcc agcaatgaag ttgaagatgc gattattcgt
     7081 ttagcgcaaa tggctcgggc agcggggatt catatgatcc tagctactca acgtccaagt
     7141 gtggatgtta tcacaggaat catcaaagca aatgtacctt ccagaatggc atttgcggta
     7201 tcaagcggta cagattctcg gacgatcatt gattctaatg gggcagaaaa gctcttaggg
     7261 cgaggagata tgctattctt gccaatgggt gagaataaac cgatccgtgt gcaaggagca
     7321 ttcatttctg accacgaagt agaacgggtc gttcaatttg ttacagatca gcaagaagct
     7381 cattatgaag agaaaatgat gccgacagat gaagttgaaa cgacaggtgc tccagaacag
     7441 ccacaagatg agctgtttga agaagcaaaa gcacttgtcg ttgaaatgca aacggcaagt
     7501 atttcccttc tccaaagaag atttcggatc ggttacaacc gagcagcacg tttagtagat
     7561 gaactggaag ctcatggagt tgttggcccg tcagaaggaa gcaagcctcg gaaagtattc
     7621 attgagcagg aagaaacatc agaaacgttg ccggacgata atgacatgta aaacttgtgt
     7681 gatgaagggt tgaaaaacga ataaccaata aaaagacaag gcatgatgat accaaaagaa
     7741 aaaatggttt ttttccatct tttctaatac ggtatgatgt cttgtctttt tagtttttgt
     7801 gagattaaag ttctattcga tttatttgtg aagtattgca ttaaggaaat gaatcatgta
     7861 tagtatgtag cgaaactttg agaaaaagag ggaaaatact ttggaaaaac agtccattta
     7921 tggcttgacg aatgaagaat taatcaattg gtttatagaa aacggcgaga aaaaattccg
     7981 agctgcccaa gtttgggaat ggttgtatca aaaacgtgta agtaatttca cagaaatgac
     8041 gaatctatcg aaacaattga tcgaaaaatt atcggagcat tttatcatca atcctctaaa
     8101 acagatggtc gtccaagaag cttcggatgg tacagtaaaa tatttgtttg aactccctga
     8161 taaaaacatg attgagactg tactgatgag acaagaatat ggcttgtcag tttgtgtgac
     8221 gacacaagta ggatgtaata tcggctgtac gttttgtgca agcgggctgc tcaaaaagaa
     8281 ccgtgatctg actgctggag aaattgttgc acagatcatg atggtccaac attattttga
     8341 tgagcgcaat cttggcgaac gcgtttcaca tgtcgttgta atggggatcg gtgagccatt
     8401 tgataattac gacaatgtaa tggacttttt gcatatcatc aatgatgcca aaggattggc
     8461 aattggtgct cggcacatta cagtttccac tagtggatta gcacacaaaa tcaaggaatt
     8521 cgctaataac ggcttgcaag tcaatctggc tatttccttg cacgcgccga ataatgaggt
     8581 gcgaacatcg atcatgcgga tcaaccgaag tttcccaatt gagaaattga tggaagctgt
     8641 ggatgagtat ttagagaaaa caaaccgtcg aatcacgttt gaatatatca tgttgaatca
     8701 agtaaatgat agaccagagc atgcgcaaca attagcagat ctattaaaag ataagaaaaa
     8761 attagcatat gtcaacttga ttccatataa tccagtcagt gaacatgatc aatattctcg
     8821 cagtccaaaa gctgatgtat tgagatttta tgatgtattg aagaaaaacg gcgtaaactg
     8881 tgtgatacgt aaagaacatg gtacagatat tgatgcagct tgcggacaat tgcgaagcaa
     8941 gcaaatgaaa aaaacagttg ccaaataatc gtatcctact cgttttttca attaccataa
     9001 aaggagcagt tttcttaatt aaggaactgt tcaacttaaa taagagaaaa gattctatag
     9061 cgaaagctat aaagcttttt ttgacaagaa aaaccctcat caagcaaaga aatgtcctca
     9121 atttgatgac agcctgcttg atgggggttt tagcaattat ttaactgatt ttcttatatc
     9181 cttgctggct ttcttgtgta gcatgataag tttctacgtc aagaatggcc tgtttaaatt
     9241 tttctcgggt gatttcataa ggcacatgtt taatatcatt tgttgccatg gctttatcta
     9301 agattgcttc taaatcggtc gtgacattga gattcatgtc ggttaacgat actggaagtt
     9361 ggttcttttt cataaacaca tagattttat caaacaaatc gaactgctga tccatcatca
     9421 ataaggtcag tacaccataa ctgacagatg ctccgtgaag gtatccctcc attttttcta
     9481 gaacagtcgt accgtaatag aatgagtgtg ccatagcaga attatagtta ttgttaacta
     9541 aaacagaaac caatccggta gtaacaatga tatccgaaac gacttgttca attgcatatg
     9601 agggacgatc gtcggcacta tctttcaatg cttgcgtacc ataagtcaag agacgatcaa
     9661 tgcacatttt tccgatttgg attcctaatc tatccgtgta gcctagatca tcgccacgag
     9721 cagaaaaagt agattcgact tctttggata aagcatcgcc aatacctgcc cataagtatt
     9781 tatcaggtgc ttcggcaata attgctgtat caatgaaggt gtgtacaggt ggttttgaag
     9841 gaaagaagag tccgtccatt acgccttctt cgttatagat gacacatacc gcagtgacgg
     9901 gcgaacagtt cgaaccaata gtgggaaagg tgaagactgg tttagctagt ttttcaccaa
     9961 tgacttttac agtatcgcaa gcacggccac caccgactgc aaacaggacg tctgcttttt
    10021 ggacactttc atgctggatc aactgttcaa tatttccata agttgaatta cccccgtacc
    10081 agagactggc gacaacctct atttcctgtg tcaaagctac ttttattttg ttttctgcct
    10141 ttgaaagtgc agtcttccct ccaatcagca ctacttttgt cccatattct ttgacgattc
    10201 catttgcttt ttcatacgca tctgttccaa tggtataatt tggtaagaaa acactttgac
    10261 tcatattcat ttccttcttt cttcgttgaa acgggttaaa attttaaaga gtgatcgatc
    10321 tgactgcggc tgtagatgga gtagaggtga acctaagaca ggataagtga tgaataaggt
    10381 ggcatgaaca ccttgaaatc atcaataagt atcctaaaaa cgaacaagta caaaaacatt
    10441 gaaaacgaca ataatgaatt tttgttcctc ttagtatttc taccgattcc ctttgctttt
    10501 ttgtaattat ct
//
LOCUS       DADVXB010000095        10449 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.097, whole genome shotgun sequence.
ACCESSION   DADVXB010000095 DADVXB010000000
VERSION     DADVXB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.097"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            1..261
                     /locus_tag="KB902_001955"
                     /pseudo
     CDS             1..261
                     /locus_tag="KB902_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            261..1190
                     /locus_tag="KB902_001956"
     CDS             261..1190
                     /locus_tag="KB902_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808750.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            1187..2923
                     /locus_tag="KB902_001957"
     CDS             1187..2923
                     /locus_tag="KB902_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6808751.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(2986..3822)
                     /gene="pheA"
                     /locus_tag="KB902_001958"
     CDS             complement(2986..3822)
                     /gene="pheA"
                     /locus_tag="KB902_001958"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBB6808752.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPACLRALFRKQV
                     DLAVVPVENSLEGSVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIIGDRKMTSQQPAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(3819..4328)
                     /locus_tag="KB902_001959"
     CDS             complement(3819..4328)
                     /locus_tag="KB902_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBB6808753.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(4321..5616)
                     /gene="aroA"
                     /locus_tag="KB902_001960"
     CDS             complement(4321..5616)
                     /gene="aroA"
                     /locus_tag="KB902_001960"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBB6808754.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEMIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFMTTLFGDASLSKRPMGRVMEPLREMGADLQGKENEQYLPITVTGTNSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRISVEGKTITVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(5629..6720)
                     /locus_tag="KB902_001961"
     CDS             complement(5629..6720)
                     /locus_tag="KB902_001961"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBB6808755.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAI
                     EQQIVDYVANDFETGAEQADVILLAVPVRTTLAYLAVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADDKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMAQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPIHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(6737..7903)
                     /gene="aroC"
                     /locus_tag="KB902_001962"
     CDS             complement(6737..7903)
                     /gene="aroC"
                     /locus_tag="KB902_001962"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBB6808756.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKVAVKEYRDYLKHY"
     gene            complement(7905..8969)
                     /gene="aroB"
                     /locus_tag="KB902_001963"
     CDS             complement(7905..8969)
                     /gene="aroB"
                     /locus_tag="KB902_001963"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBB6808757.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKNLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(9002..10024)
                     /gene="aroF"
                     /locus_tag="KB902_001964"
     CDS             complement(9002..10024)
                     /gene="aroF"
                     /locus_tag="KB902_001964"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBB6808758.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         2877 a         2328 c         1918 g         3326 t
ORIGIN      
        1 ctcgattgag tcctgatttt tttctaaatt ccttaactgc cgtttcacca aaaatcaaaa
       61 aaaagcccaa caaaagccca atcaccaatc gttatgagca gatctgcgag aatctttcac
      121 agcagattgc tggacaaact cgtccattgc ttgaccctct tctttttgaa cacaccttgt
      181 tttttctgtt atataccgaa aaacggccat tcagttcaaa acaaggctct aaacaaaaac
      241 agtcgatcac ccattcattg atggatagcg acgattcgtt tactatttat cctgtttcta
      301 ccttttcgga agaatccggc tatgtaatca atactgattc caaagataca cttaggaagt
      361 ttgttcaaaa gtttcgtcaa gaagtttttc caggtgattt ttttgttgtt tctgattctt
      421 ttgcaatcca agatatcaat gaaatattcc aagagatcag aaattgcacc aaaggacaac
      481 gtttctatca taagggaaag aaccttgctt atcagcatga acttcttccg ttattaacca
      541 accacgagca gcaagcaagt agttatttaa caaaaatcgt tcataaagac tacgctttag
      601 ctgtcaaaga acttgagaat ttcttcacga cgatattgga acagcctatt gatccagctt
      661 atttgaaaca tgaggcaatc aatcgtttct atgcattact caacgctttg gctgacgagc
      721 atgttgggaa tgaagaactt tctttgctca agatcgccct tccttcttta ttagccgatg
      781 ctgagtattt cgaagatttt tctattcttg tcaaagaaac acttgagaaa ctcacccact
      841 tttctgcaaa tgcaaaaaaa gacaatttcg atatcttgac tttgatctac gagttcgtcc
      901 aggaaaatta tgagaaagaa atcaatttac aacttttatc cgaaaaatat catttttcat
      961 atagctatct ctcagccatc tttactgaaa aatttggtat caacttttca aaatatctaa
     1021 aaaaagtccg tatcagtaaa gccaagctct ttttgacgga aacacggctt actttgacgg
     1081 aaatctgtga gaaagtcggc tataccgaac tgggttattt ctccagagtt tttaaagaag
     1141 agacaggaat gacaccttct caataccgta aaggaacttt tgtaaaatga gaaaaaaaat
     1201 caaagagcat gaactctttg ccaaacttct gttcattttg ttcatcggtc tttttctgca
     1261 agccatcgtc atttctttgt ttatttatca tcgatcaagg gatgcctata tccagctgtt
     1321 caatcaatcg aatgatgtgg tactaaaaaa gattcaatct gaatttgaaa gtttgaatga
     1381 tacaatcgag aatacattag ccgcttttga ttctaatcca gctgtcaaaa gctatttttc
     1441 caatgatcca gcccaacata tggaacagct tcagcaacta agaacaatcc aaaaaatgaa
     1501 tgactctctt tcaaaaatcc atccaatgat cgattacgat gtattgatct ttggagaaaa
     1561 tggaagaact tttgtcggaa acgacatgct cactgccgta tctgccgatt ctttttttca
     1621 atctgcgatt gctcagagag tgaatgaacg tgctgctgat acacaaatgc tttttgcaca
     1681 ccacggattg actcttcgcg ataagaaagc acctagcgtc ttctttgtca aaaaactgaa
     1741 aaatacattg aatcacgttt acggatatgc tgttttatcg atctcatcca agcaactagc
     1801 gaatcttttt caatctgtag taaatcctga gatatcgaag atctccttca tgaacgaaga
     1861 acagacgatc atcgcatcaa atgaagaaaa tacaattggg agccgatcaa tgattttcaa
     1921 aaaactaaca gtaggtgaaa caacgatttc aaatggacag cagttgaccc gtcttcctct
     1981 gtaccgccag gattgtacat tactcagtca agtcgatctt cattctttat ctaaccaaat
     2041 gggcgtgatt tttccgatta ttttgtataa tatcgtgaca cttgcttttg ctggctcatt
     2101 ggtatttatg tatttggatc gacacacaaa atcgatctac cgcttgattg attcgctaaa
     2161 acggctagag gaagatggct taaaagctac tgttcctgta caaggaagcc atgaagtcca
     2221 attgctaggg aatacgatca atcaattgct aagtaatgct cagcatcatt atgaacagac
     2281 gatccaagac gaaaagaaga aacgttcgct tgaaatccaa actatgcaag cacagataca
     2341 gccccatttt atttataata cgctgactag cttgaaattt ttgatttggc agaaaaaaac
     2401 agatgaagca gttcaaggaa tcgacagttt cattacttta ctaagaagta cgattgggaa
     2461 aaaagaagaa gtgattccag tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct
     2521 tttgagtatg cgatatggcg aaagaatctc ggctaaaata atgattcctg atgaactgca
     2581 gtcattatct atgccgaata tgatccttca accaattatc gaaaacgcct atcttcatgc
     2641 ttttcacaat aaaacgcaag gattcatcac ggtgtacggc aaaacaaaaa atcagcttct
     2701 tttattcgaa gtgattgata acggcgatgg cttcgatact gaaaatacca aacaaaaaaa
     2761 tgatcatttt tcaggaatcg gcatcagcca tgtagatgag cggatacgcc taatgtatgg
     2821 cgatgcatat ggcttaacga tccaatcagt gattgggaca ggaacgactg taacgatttg
     2881 tctaccgctt cttcctaaaa atcaatcaga atatcaaaaa taaagaatag ccaagcactg
     2941 atttttttat tttaagttaa ataaatcaat cagtattctt gactttcatc tacgcgtctc
     3001 ttctactgtc agcactggat aacagcccaa tatttgactt tctcctccga gcatcttgat
     3061 ttcttggagc gcattctcta ctaatgtcat tgggcggtcc aacaacaaat cgatcacgaa
     3121 aaaatattct cccaaactgg ttttcaatgg tcgggattca atcttactta agttgatctc
     3181 ccgccatccg aaagctgcca gcattttatg aagcatccct ggccgattag caggtagtgt
     3241 caagatgaca ctcattttta ctggagctgg ctgctggctg gtcatctttc gatcacctat
     3301 gatccaaaaa cgtgtctgat tcaactcatt atcttggata ttctcagcta agatctccaa
     3361 tccaacatgc tgtgctgttt ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc
     3421 tgctacatac attgctgcag cagttgttga ttctgttgct actaaaggaa cattaggata
     3481 atgcgtttct aaaaactgtt gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt
     3541 aatctttgtt gctggattgc ctaaaagctg ctgcttgata ggaagaacga tttcactttt
     3601 aacttcgact tctggatgtt tggaaagaag atcgattgtg tgatgaacag atccttccaa
     3661 tgaattctct acaggaacga cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca
     3721 agcagggatg gaagcatacg cagtcaattg ttctgtagga aatagctgac aagccgcctg
     3781 ataagtgaat gaactttctg gccctagata gctgacgttc atatgctttt gatcctttct
     3841 ataatggtat cgatgatctt ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca
     3901 ctttcttcat accaagaaag tcgttgtgcc aataatgctt ttatttcttc tcttgttttt
     3961 ccaagagcta aaggtcgaat agacgtttca tcttgttgga tacgatcaac tagacagtcc
     4021 gcttctgcct ctaagtaaag aacaatcggc tgtgttttta aaaaacgccg attttctgca
     4081 ctttggacaa tccctccacc agtcgcgata attttatctt catttgacag ctttcttaaa
     4141 atatctgact ccacttttcg aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc
     4201 gacaattgga tatgttcctc aatctttgta tctaaatcta catactcttt ttgtaaacgt
     4261 tgagctaacc ctttaccgat tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg
     4321 ctagccatga gcttctcctc ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata
     4381 agagattgaa acagcttcag ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc
     4441 tacttgcagc atcataccga ttcgatgatc gcctctgctg gacacttttg cgccatgcag
     4501 aggtgtcggc ccatggatga tcagaccgtc tgctgtcgct tttatctttg ctcccatttt
     4561 ctgtaattct tctgccaccg catcaattct gttggtttct tttactttta attcttctgc
     4621 gtctttgatg atcgtgattc cttctgcttg agtagccact aaagctagaa tgggcaattc
     4681 atcaatcaga cgtggaatga tttctccacc aatcgttgct ttcttcaaat gactcgtctt
     4741 gacacttaaa tcagccgatt ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc
     4801 catctcctcc agcacatcta agataccggt tcttgttgga ttgaccccga cattttttaa
     4861 taacagttgg ctttccggaa caagaagccc tgctgctaga aagaaagcag ccgatgaaat
     4921 atcgcctgga acagttatct gttgaccagt taatttttgt ggtcctgtta ccgtgattgt
     4981 tttaccttct actgagatcc ttccgccaaa ttgacgaatc atttcttccg tatggttacg
     5041 ggaacgttct ttttcaacga ttacggatgt gccttctgct tgtaatgccg caaacagcaa
     5101 agcagatttg acttgcgcac tggctacagg catattgtat cggataggtg ataaagagtt
     5161 ggttcctgtc acagtgattg gtagatactg ctcattctct tttccttgca agtcagcgcc
     5221 catctcgcgt aaaggttcca tcactcgccc cattggacgt ttagacaacg aagcatcccc
     5281 gaacagagta gtcataaaag gctgtccagc caaaataccc atcaataaac gtatggtcgt
     5341 accggagttt cccatgtcga ttgattcggt tggttggaca aatgagtggc taccgcgacc
     5401 atgaatcttg atcatctctt cctcttcttc gatttcaacg cctaattgct ggaaggcatg
     5461 taaagtactc agacaatctt ctgcgcgcaa aaaattttgt atagtcgtcg ttccttccgc
     5521 aattgcccca aacatgatgc tgcgatgaga aattgatttg tctgctggta tcctaacagt
     5581 tcctcttaat ccatgtattt gttgtaataa ttgcatttat ccagcctcct atttgatcca
     5641 gcaatgataa ctggtattag acataatgat tctttttgct tgtaacaaat cctgttggtt
     5701 tttaaaactg atttgcagta ttcctaaaat atcttccctg gtctcttgga tcttcaaatt
     5761 aatcaaagaa actcccgctt ttccgatcag tccagttact tctgcaataa cgccaggttc
     5821 atctggcaca tcgataaata aatcaaagaa ggcaggaatc gcgccttgct tatggatagg
     5881 caactggtct cgactttctt ttgcccgatt gaaaaaagaa aagatttccg attggttctc
     5941 agtcatgatc cattctgcta tttgtgccat ttcttgctgc caatccgcca atcgttccaa
     6001 taatatctgc ttattgctca acaaaatatc tgtccacata acaggatccg aggaagcgat
     6061 cctagtgata tctcgaaagc ctcctgctgc cagttgtttg gctcgcggat actcttgatt
     6121 gaattgttct gcctgattga ctaagccagc tgccagaata tgtggaaaat gacttagcat
     6181 tcctgttata cggtcatgtt ctcttgctgt aagagttacg tattttgctt tggttccgca
     6241 aaatagttct tgcagttttt caacatcttt tttcgtcttt tccaaaggtg taaagatgta
     6301 ataggcattt tcaaatagtt tatcatctgc tgcctgtata cctgatttat gagagccagc
     6361 cattggatgt ccaccgacaa accgaagatt tttctgctca gcggatgtca cgacttgctg
     6421 cttcgtactg ctgacatccg taatgatgac gtgatcagac aagttgattc tttcaaggac
     6481 agcaagataa gctaaggttg tacggacggg aacggctaat aagataacgt ctgcttgttc
     6541 tgcacctgtt tcaaaatcat ttgcaacgta atcaacgatc tgctgttcta ttgcttgctc
     6601 acgggttttt gactgactat cccaaccaac tactatcagt tctggattgg tctgacgaat
     6661 acaaagtgcc atagaagcac caatcagtcc aagccccacg ataaaaacat gttgtgccat
     6721 cttatttgcc ccctttttaa taatgtttca agtagtcacg gtactccttc actgcaactt
     6781 tcaactcaac aagcgaatca cttgggaatt ttgacaatag ctctgtcgct accacagtgg
     6841 ctacaacatt ttccgcaacg acgctagctg caggaactgc tgtactatcc gaacgttcta
     6901 cacttgcttt gtaaggttct tttgtatcga tatcaacact ttgaagtggc ttgtacaatg
     6961 tagggatggg tttcatgacc ccgcgaatga caagtggttc gccattggtc attccgcctt
     7021 cgaagccgcc tagattattg gtacgtcgga aatagcctct ttcttcttcc cataggatct
     7081 catccatcac ttctgagcct ggtaatgaac cagaagtgaa tccgacccca aattctacgc
     7141 ctttaaaagc attgatacta accacagctt gtgcgatttt ggcatctagc ttcgtgtccc
     7201 attgtacgta gcttcctaat ccagctggaa cacctccaac gagcacttct acaattcctc
     7261 cgatcgtatc tccatttttc tttgtctgat cgatcaaatc ttttattctt tgctcaactg
     7321 ctggatcaac aactcgtact tctgacgctt cagaaatttc tttgatttct tgaatcgaga
     7381 tatttccagg tatttctgct tggattccac caagacaaat cacgtgtcct gctacgatga
     7441 tgtcaagttc ttccagaatt ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct
     7501 ctcttgcaga ggaccgttca agcacattcc gaagatctcg atgatggtat ttcataccgc
     7561 ctaccaaatc cgcgtgtcct ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt
     7621 caggcacttc tgctacagac atgacagttg tccaattttt ccaatcttta ttttctacca
     7681 ctaaagtgac aggtgaacca attgttttgc cgtgacggat gccagacgtg atccgaacac
     7741 gatctttttc gatcttcatc cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt
     7801 cgtgattgat ttcttcttct gacagaggta atcctgctgg tagtccttca ataatcgctg
     7861 ttaattctgg tccatgggat tctcccgcag tcatataacg catcttacag tcctcctaag
     7921 taatctttga atgtctctgt gggaacagga acgatttttg cttgcccaat cttttctagc
     7981 aagatgatat tcaattggct tcctcttgct ttcttatcat gggttatcgc gtggaataat
     8041 tcatctggat gacttagatc atacgtaatc ggcagatgga atttttgaag tatcctttct
     8101 aaagcagctg tcgatccagt tggagacaag ccgatttttt ctgcatgaga agtgatggct
     8161 accattccaa tagctactcc ttctccatga ctgactaccc catatcctgc tgtattttca
     8221 attgcatggc caattgtatg accaaaattt aaaataagtc gatttccttg gtcaaagaca
     8281 tcttcttcca ctacttttcg tttgatttcc aacgtagcag taatgattgg aacagcatgt
     8341 tccagaagat ttttttcgtc tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct
     8401 atagctgctg atttgatgat ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt
     8461 tttagaacct caggatcaat caatacacca gctggctggc taaatgttcc gacaaggttt
     8521 ttcgctttgt ttgtattgac tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt
     8581 agcgtagtcg gaatttgaac gaaatggatc ccacgcatga acgtcgaggc cacgaatgcg
     8641 gctagatcac ccaccattcc tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca
     8701 ttatctgcta aaaaatcgta taactcagct gcttgttcta aagatttact ggtctcaccc
     8761 gccggtacga ttgaaaggac tggttcaaaa ttagcttgtc tcaattggaa catgattttt
     8821 tctgcatata gtggagcaac gtttgtatca gtgatcacag ctactttttg aggtctccaa
     8881 atcgtttgaa gccatgatcc agcctgttct agtgcgcctt tttcaatatg aatatcgtat
     8941 ttttggttat caacatgtac agtaagcatt catttcactt ctttctttta aaaagctgga
     9001 attaatcgag tgtctgaatc ttttccattg cttctttcat gatcgcaact tctttcatca
     9061 tgcgtgagta agtcttttca ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat
     9121 caggatggat ctctacgatc atgccatctg ctccgcttgc cacacccgca cgagccattg
     9181 gtggtacaag ttcccaaatt cctgtaccat gacttggatc aacaatcaca gggaaatgag
     9241 ttaatttttt catcaatggg acagcactta aatcaaacgt attacgtgtc gctgtttcgt
     9301 aagtccgaat cccacgttcg ataaaaatga caggagattt gtcttcgact gcaatgtatt
     9361 ctgcagcatt aagccattca ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt
     9421 tacctgtttt accgacagca gatagcagtt taaaattttg catattacgt gcgccaatct
     9481 gtaggatatc gctgtactca gccaccatgt cgatatgccc ttcatccatc acttcagtaa
     9541 tcactttcat tccaaattca tcagccgctt gacggatgta tttcaatcct tcttcttcta
     9601 aaccttggaa agcatacgga gaagtacgtg gtttgaaggc accacctcgc agaatttttg
     9661 cgcccccggc tttggccatt cgcgcacatt ctctgatttg gtctaatcct tcgatagaac
     9721 aaggaccagc catcgtcacg aaactgccgt caccaatttt tactccgtct acatccacga
     9781 ctgtattgcc aggatggaat tctcgagaag tcaatttgta tgtgtttaaa atacgcacag
     9841 cattttctac tccttcatag cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt
     9901 ttagtccaat cactactcgt tctgttcctt gatcgattga gactttgaat ccttcttttt
     9961 cgatatgatc gacgactttt tttatttgtt cttccgttgc ttcttttttc ataattacta
    10021 tcattgtttt tcccgctttc ttttgtttac ttatctatct tggctgattt tctctacttt
    10081 ttcaaggtgg ttttacatta attcctacta aatgaccgtg tcctgttgtt ctcattttcg
    10141 ctccttcttt cctacttatg acccagataa tcaacaaaaa aagatgtccc tgtaggaaat
    10201 tgcctctaca gtgaacatct tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc
    10261 cactatagat gaatttctct acgtggctgt aagtcgtgtt taaaaatctt tagccatcat
    10321 agatacaaac ctggtttgtt tgtacccacg aagtcatgaa tacaaaccta tctaaaatag
    10381 ctaaagtaat acgtattcag ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa
    10441 ctgatgtaa
//
LOCUS       DADVXB010000096        10394 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.098, whole genome shotgun sequence.
ACCESSION   DADVXB010000096 DADVXB010000000
VERSION     DADVXB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.098"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(338..2719)
                     /locus_tag="KB902_001965"
     CDS             complement(338..2719)
                     /locus_tag="KB902_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6808759.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2709..3356)
                     /gene="recU"
                     /locus_tag="KB902_001966"
     CDS             complement(2709..3356)
                     /gene="recU"
                     /locus_tag="KB902_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBB6808760.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3420..3959
                     /locus_tag="KB902_001967"
     CDS             3420..3959
                     /locus_tag="KB902_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBB6808761.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4049..4468
                     /gene="gpsB"
                     /locus_tag="KB902_001968"
     CDS             4049..4468
                     /gene="gpsB"
                     /locus_tag="KB902_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBB6808762.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4490..4857
                     /gene="rnpB"
                     /locus_tag="KB902_001969"
     ncRNA           4490..4857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KB902_001969"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5066..6232
                     /locus_tag="KB902_001970"
     CDS             5066..6232
                     /locus_tag="KB902_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBB6808763.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6278..7774
                     /locus_tag="KB902_001971"
     CDS             6278..7774
                     /locus_tag="KB902_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBB6808764.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMEDLYFNVYQVK"
     gene            7855..8538
                     /locus_tag="KB902_001972"
     CDS             7855..8538
                     /locus_tag="KB902_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6808765.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9183..10373
                     /locus_tag="KB902_001973"
     CDS             9183..10373
                     /locus_tag="KB902_001973"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBB6808766.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKRM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         3353 a         1831 c         2195 g         3015 t
ORIGIN      
        1 ctcaaaatga agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg
       61 ataataacaa tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc
      121 gatttaatta taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt
      181 ttctaatttt taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa
      241 atcatgtaat acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa
      301 aaaagaaacc acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg
      361 tgctgctgga tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg
      421 aagaagcagg aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa
      481 ccgttgttga agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag
      541 cagttgattc gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc
      601 ttccaggagt ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg
      661 atctagctgt atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg
      721 gcatctccca gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa
      781 catcagaggc tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg
      841 tccacacgga aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc
      901 cagaagaaat accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac
      961 cggcttgata taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt
     1021 ttaaaatgtc tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct
     1081 cataagtttc ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat
     1141 aagtccctcc attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt
     1201 attttgtccc atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac
     1261 tgtattcgat cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga
     1321 ataatttgac tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc
     1381 ccatatattg attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg
     1441 cgtcagtaat agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg
     1501 tgacaggttt catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta
     1561 aagttacgtc ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg
     1621 tgtcgataag ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg
     1681 tgttgacgat atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta
     1741 aaccgtctgt gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga
     1801 cataattatc gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg
     1861 ttaccggtac attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca
     1921 tcgtatacaa aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat
     1981 aggcggaagg ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg
     2041 ataatttctt accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca
     2101 tatacacttt atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc
     2161 ttacagccat ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg
     2221 agaagaagga aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag
     2281 aggtaaagtt agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat
     2341 aaaaacggcg atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg
     2401 cagaaatttt ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat
     2461 atagtttgga agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg
     2521 cgtaatacca gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc
     2581 ctaaaaggat cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt
     2641 tgccagaatt cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc
     2701 tagtttgttc atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag
     2761 tcaaccgcgt ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt
     2821 tcttcgatca aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa
     2881 gcaatcaaat gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag
     2941 acaaagcaga ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg
     3001 aagtttttaa agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa
     3061 aagcctcgat agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg
     3121 atcacagcag cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt
     3181 ttatggataa ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct
     3241 tcaaagcgca tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt
     3301 tcgacgggag aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt
     3361 aatcacactc ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga
     3421 tggataagtc aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta
     3481 aagaaaatga tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt
     3541 tagcagaaga agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg
     3601 ctgtgcaaat agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt
     3661 atcctttttc tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag
     3721 cagaacaatt agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc
     3781 agctaaagaa tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg
     3841 atgaagaatt ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag
     3901 atcatcccta cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat
     3961 cgatattgtg tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat
     4021 tacgtaaatg aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat
     4081 tttacaacaa gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt
     4141 cttagacaat atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga
     4201 agaaaacgat cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca
     4261 aacacgcgtg caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt
     4321 aaaacgcttg tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag
     4381 tgcagtcaaa ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga
     4441 tgataatgaa aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta
     4501 atcgcggtct gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg
     4561 tagtgttcgt gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa
     4621 caagctaagg cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct
     4681 ggggaaaccc atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta
     4741 ggggcgcttt ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg
     4801 gttaccgctt tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac
     4861 cgcaaacatc agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac
     4921 atttgaaagc tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg
     4981 tatcaccggt tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct
     5041 ttttttataa ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac
     5101 tgcggcaagc gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg
     5161 ccaagttgag aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa
     5221 tttatggtta cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac
     5281 gtttgatgaa ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga
     5341 tgcagctttt cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg
     5401 ccaagcgatc acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc
     5461 ttctgtacca ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga
     5521 ccatgtgatg gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt
     5581 agaaaaaggt ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa
     5641 ttggcgaaaa gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga
     5701 agcagcctta ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc
     5761 ttgggattgg ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc
     5821 agattatgat attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat
     5881 tgccaaagcc aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc
     5941 agtcaaagac ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg
     6001 agaacgtcta ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt
     6061 ccgtccatta aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt
     6121 ttacggacaa aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct
     6181 attccagtat tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta
     6241 attgattcat tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca
     6301 agaagtaaaa gaaatcaatc ttctacaaca agctttagga atccttgatt gggatacaca
     6361 aacaggtatg cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag
     6421 catttatttt tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga
     6481 acatccggaa gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta
     6541 tgatttggaa catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc
     6601 agcacacgga caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc
     6661 attgaatcaa aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa
     6721 gacgaattat gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga
     6781 taaggtattt gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa
     6841 agggactgaa cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag
     6901 atttgtagtg aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga
     6961 cactgtccac ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg
     7021 gaacgaaaca gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat
     7081 gtatgaacaa gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat
     7141 gggtatccat gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt
     7201 ctggaaaaag caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc
     7261 ttttgacaaa ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc
     7321 agacagtttg acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt
     7381 caatgaaggg gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta
     7441 tctgggaata cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg
     7501 tgcaagcttt ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact
     7561 tcattctttg cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc
     7621 aatcaaaaac tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca
     7681 attaatcatg gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgga
     7741 agacctgtat tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa
     7801 ttcatctaat ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat
     7861 aaattacaag tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat
     7921 gggagcgatc ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg
     7981 caggcagacc gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa
     8041 gtcgttaaaa atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca
     8101 atagtagagg aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa
     8161 aatctctctg aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt
     8221 atcgaagcat taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg
     8281 cacccgattt ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga
     8341 aaaggcacga cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg
     8401 aatactgatt acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta
     8461 gaagaatttt ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc
     8521 aaaaataaca aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga
     8581 tcattttccg taaaatttac ttctggaaca ctgtttacca agaggtcatg agcctgccgt
     8641 tcagctccga gtcacaagga acaatttcaa aaaatagctt ctcatgtttg atgaatattg
     8701 taacttgtga ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac
     8761 aagacttttg tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca
     8821 gagagtaaaa ttaaaaattg ctgataaata aagatggaag ttttatgtat ttttattggt
     8881 ctatgcaata aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat
     8941 caatggttgt gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt
     9001 aattgttcat actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg
     9061 ttaaataatt ctcataatca gtgtaagcgt tatcaaaaat atggcatact tgctttgtag
     9121 atgaatgaca cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga
     9181 caatgtcttc caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa
     9241 aggggttata caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag
     9301 acggaaaaag gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag
     9361 aattgaaaaa agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc
     9421 gaacgatcaa tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca
     9481 aagggacaga agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct
     9541 ctgcagtaat gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta
     9601 ttgacggttg ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag
     9661 accttgagaa aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata
     9721 tcacagatgg tgttttctcc atggatggag acattgcacg attgccggaa attattccga
     9781 ttgttgaaaa atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg
     9841 gaaaaggtgc aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg
     9901 gcacgttatc gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa
     9961 tcgactggtt gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg
    10021 cagctgcagc tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa
    10081 aagtttggga aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg
    10141 gtatgtctga aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt
    10201 tctctaagaa gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc
    10261 ctcttgggac aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg
    10321 atgaagcagt agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt
    10381 tagttttttc gtct
//
LOCUS       DADVXB010000097        10361 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.099, whole genome shotgun sequence.
ACCESSION   DADVXB010000097 DADVXB010000000
VERSION     DADVXB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.099"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(27..695)
                     /locus_tag="KB902_001974"
     CDS             complement(27..695)
                     /locus_tag="KB902_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6808767.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            829..1116
                     /locus_tag="KB902_001975"
     CDS             829..1116
                     /locus_tag="KB902_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808768.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1369..2328
                     /locus_tag="KB902_001976"
     CDS             1369..2328
                     /locus_tag="KB902_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6808769.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            2597..4135
                     /locus_tag="KB902_001977"
     CDS             2597..4135
                     /locus_tag="KB902_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBB6808770.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            4132..5097
                     /locus_tag="KB902_001978"
     CDS             4132..5097
                     /locus_tag="KB902_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808771.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            5084..6406
                     /locus_tag="KB902_001979"
     CDS             5084..6406
                     /locus_tag="KB902_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6808772.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GDAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      6469..6573
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6647..7390
                     /locus_tag="KB902_001980"
     CDS             6647..7390
                     /locus_tag="KB902_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808773.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            7405..8397
                     /locus_tag="KB902_001981"
     CDS             7405..8397
                     /locus_tag="KB902_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6808774.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            8409..9146
                     /locus_tag="KB902_001982"
     CDS             8409..9146
                     /locus_tag="KB902_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6808775.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            9136..9858
                     /locus_tag="KB902_001983"
     CDS             9136..9858
                     /locus_tag="KB902_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6808776.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9942..>10361)
                     /locus_tag="KB902_001984"
     CDS             complement(9942..>10361)
                     /locus_tag="KB902_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6808777.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3415 a         1785 c         2161 g         3000 t
ORIGIN      
        1 ttaaataaag tagtgaaaaa taagaatcag tgctctaact gttcaagagg atcaagtggt
       61 tcaaatgttt ctgtagtctg ttttgcttcc aattggggca aaacagatcc aatttccaga
      121 tacttcactt tattcaatgt ataagataga atagaacagc taagtaatgt atacagaaaa
      181 tgtgtgagat ccaaataaag caaggagaca actaaaatac caaaagtaat caagaaaaga
      241 cttttgccaa tcttaatatg aaaatatttt tcaatggctt gataaatgat atctgttccg
      301 cctgtgcttc cgccgaatcg aaagacgaga ccgcaaccaa tgccagaaag aatacctgtc
      361 atcaaactat tgatcagtag actatctaca gcaaaatgta tatgaaggct ctcccataaa
      421 tgtaaaaaga aaactagcgc aaatgttccg acgatcgtcc ggagaaaagc gtgttttcca
      481 aaaagaaaca atgagataag caataaaggt aaattaaaaa gcagtgaagt gacagaagga
      541 gcgaatccaa aaagattatg caaaagcaaa gcaataccag taaccccacc atctgccagc
      601 ttagatggaa tattgattcc tgtcacagct aatccgtaga ttcctgcgcc taaaatgatt
      661 ccgcacaatt ctgtaaataa atttaatttt ttcatttcta gcctcttttc ttttgaaaat
      721 tttcagcaac ttctttatta tactgactta tactcttact tcaagaggaa aatgaaaaaa
      781 aattattttt ggctgtttct ttttatttat caaataagga gtggaaaaat gcgagcagca
      841 gacttattga caattcttac aaaatcaccc aaaaaaacag agtatcaagg agtttttttg
      901 gctcaagaac aaaaactggt gcctgtgaca atggtccaga taaataaagc aaatcaattt
      961 atctttttat ttgaacacgg caaagcacca cttgctatga aagacatctt tctttttttg
     1021 atgaagaacc gtgagaaagc tgtttattat cagtcaaaag aagaactcat tcctctttat
     1081 ggagtgaaag agatagaaaa taaagtggtg atataagtaa aaataagaaa acaagacgtt
     1141 tatgatgtca aaacaaccat tttttacatt tttggcaaaa aagtgtcatg atacagtata
     1201 atattcgttg aacaggccaa taaaggtgtt ctcccccacg agatttctac tttattggct
     1261 gtttcttttt attaacgccg attgtaaaat taagctagac aactaaaaaa gtcatttgtg
     1321 ctacactcaa aatagttccg tccaaagaat tataaggagt gagtacaaat gacctatacc
     1381 catcttacaa cggatgaact tgtaatgata gagtcttatt tcaaaataaa tcaatctgtt
     1441 gcgaaaactg cgcatttctt gaatcgttca agacaaacga tccataaagt atacctgttc
     1501 ttcaagcaag gaaaatcagc cttagagtac tatcaacagt ataagaaaaa caaatcaaac
     1561 tgtggtagac gcccgcttgt tttacctgag gaacaatcag aatatattca aagaaaggtt
     1621 gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat tcgttgttct
     1681 gctcgtacca tttatcgtat gttcaaaaag gggctattta atccttctga cttaccgatg
     1741 aaaggcaagc gtaaaccaaa tggacatcaa gaaagacgtg gaaaacaagc tttccgtcgc
     1801 tctattcatg aacgtgaaaa agattatagc caattctcaa atgagtttgg tcaccttgaa
     1861 ggtgacacta tcgtaggttt gaaacataaa agtgctgtaa ttaccttagt tgagcgatta
     1921 tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat tgaaaacaaa
     1981 ttaaatcatt ggtttgaatc tgtaccgaaa aatctattca aatccatcac ttttgattgt
     2041 ggaaaggaat tttcaaattg gaaacagatc agtaatgcca atgatattgc catttatttc
     2101 gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg attgttacgt
     2161 agagatggtt tattgaaatc tatggatttc aattcagtag atgaatcttt tattcaatct
     2221 gtcgcatcga aacgaaataa tattcctaga aaatcactga attatcgaac acctttggaa
     2281 gtatttttga gttacgtaag tattgatgat ttgtctaact taatttgaca attaagataa
     2341 aataaaagtt gtgtgtgtaa aaaagatata gctgattcca agtgacaatt tcgtatagat
     2401 ttttatggta ttcgtagtga aaaaacgaga accaaaaagt tgatccgact ttgttgcttg
     2461 gattcttttt ttgtcagcat atttagaggt atttttttct tttttttgtt cgtgctgtaa
     2521 ggttaaggca agacaagtta gttgggaaaa aggaaagaaa tgtttatact taaagaataa
     2581 cagaaaggaa ggtcgcatga ataattttat acaaacatta agtgaaagaa aaggcgagtt
     2641 gctggaagct gcatttcaac atctgtccat ttctctcatt tctttgctga ttgcagcact
     2701 gattgctatt cctttagcga tttgggcagc caatcataaa aaaatggcag aagtcttatt
     2761 gcagatcacg ggtgtgctcc aaacgattcc ttcacttgcc ttattaggtt tacttatccc
     2821 atttgtaggg atcggaactg ttccagcatt gattgcactt gttatttacg ctttgcttcc
     2881 gattttccaa aacacgtata ttggtctagc tgaaattgac ccgtctattg aagaagcagc
     2941 ggtagcattt ggtatgtcca gaatgagacg cttgctgaaa gtagagcttc ccatcgcatt
     3001 acctgtcatt atctcaggta tccgaactgc cttagtttta atcatcggta cggctacttt
     3061 ggcagcattg atcggagcag gtggattagg gacatttatt ttgttaggta ttgaccgaaa
     3121 tacacctgtt ttgacattga ttggtgcgat cagttctgcc ttgcttgcaa ttatattcag
     3181 cggactgatt cgctggttgc agcataagaa acctcgatat tccatcatta ctttagcagc
     3241 agtggtgtgt ttatttggcg gcgtttcttt atatcagtct gccttgttta aaaatgaaac
     3301 catcacgatt gctggaaaat taggagcgga acctgaaatc ctgatccaaa tgtataaaga
     3361 attgattgaa gacaacacaa aaacagaagt tgaattaaaa ccgaattttg gcaagacgag
     3421 ttttttgttc aatgcactgg atcaaggtca aatcgatatc tatcctgagt tcacaggtac
     3481 tgtcctagaa agcttggtga aggtacctga agcaatgaaa agtgctgatt tgacaaaaga
     3541 aaaaacatat gacgaagcag aagaattatt gaataagcaa ttcgatatga cattattaaa
     3601 accaatggct taccaaaata cgtatgcctt ggcagtcaag agatcttttg cgaacgaaca
     3661 tcaacttaaa aagatttccg atttggcagc tatctctgat cagatcaaag cgggattcac
     3721 actggaattt attgatcgtt cagatggata taaaggaatc caagaagcat atggcttgaa
     3781 tttttcaagt gtacaaagca tggagccaag tttgcgttac caagcaatca ataatggaga
     3841 tgtcaatatt gtggatgcct attccacaga tagccagctc aaggagtacg atctagtgac
     3901 tctagaagat gatcgagggt tattcccagc ttatcaaggc gcaccgctga tgaaaaaaga
     3961 ttttgctaaa gaacatcctg aaatcgttaa agcactgaat aaattaagcg gaaaaataac
     4021 agaggatcaa atgattgata tgaattacca agtcaatgtc gaaaagaaaa agccgacaga
     4081 agtagcacga atcttcctga aaaatgaagg attagtaaag gaggaagatc agtgactaaa
     4141 ttaatcgagt tcaaacatgt gcaaaaaaag tatgatggaa agtatgtcat cgatgaccta
     4201 aatctggcaa tcaaaaaagg agaaatcttt gttttggttg gtccttccgg tagtggaaaa
     4261 acaactactt tgaaaatgat caatggatta tctaaaccat cagcaggaga catctacttc
     4321 aaaggaaaat cgttaaatga atataatctg cagaaaatgc ggtggaatat gggatatgtg
     4381 ctgcagcaaa tcgctttgtt cccgaccatg acagtcaagc aaaatattga agtcatccct
     4441 gaaatgttag gttgggaaaa gcagaaaaga gcagaccgtg tagatgaact tcttcaaaaa
     4501 gttggcttat ctcctgatat ttatcgagat cgtatgccta gagagttgtc tggaggagaa
     4561 cagcaacgga tcgggatcat ccgagctatt gctgcaagcc cagatgtgat tttgatggac
     4621 gagccattta gcgcattaga tccgatttca agaaactcat tacaagaatt ggttttgtcc
     4681 ttacacgaag aattgggcac gaccatcgtt ttcgttacgc acaatatgga agaagcaatc
     4741 aagctaggtg atcgtattgc atttatgaag gatggagaaa ttatccaatg tgacacacca
     4801 gagcagttat tgatgaatcc taaaaacgac tacgttcggc atttctttga tgaaccgaaa
     4861 cagacgaaag agtggcgagt agaagattta gtcgtcaatg gatatttctt aaatgaaata
     4921 ccagaaaatg ctcgtcaaca agtttgcttt gatacgccta tgaaagaagt atattcgctt
     4981 ctttcggtgt atccaagcat tgtgatagta gaaaagcaaa gaagtattgg gtcgctgaca
     5041 agtaaagaaa tctttgcttt tttaagtcga gaggaggaag gaaatgaaaa catatgatgc
     5101 aatcatcatc ggttcaggtg tgagcggctt aagtgctgct tatggattga aagaagcagg
     5161 taaaacagta ctagtggtcg aagaagatct atggggcggg acttgtccta accgtggatg
     5221 tgatcctaaa aaagtcttgt taagtgcagt agaggcacgt aatcgggtaa aacaattgag
     5281 tggaaaaggt tttaacgaga tcccaactgc caactgggaa gaacttcaaa aattcaaacg
     5341 aacatttacg gatccagtcc cagaaagccg aaaaaaacaa ttagcagaag ctgaaatcga
     5401 tcatctttca ggaaccgctc gttttttgga tgattcatct attgaagtca acgaagaagt
     5461 cttccatgcg gattacttag ttttggcaac cgggcaaaga cctacgatct taccagtgga
     5521 gggaaaggaa tacttgaaaa ctagtgcaga ctttttatca ttgcctgtac tgcctaaaga
     5581 aatcattttt atcggtggtg gttatattgc ttttgagcta gctacgattg ccaatgctgc
     5641 agggagcaaa gtaaccattg tccatcataa tcaacggcca ttaaaagaat ttgaggcgtc
     5701 tttggtagag gaagccgtcc atcaaatgga agcatctggc attcagtttg cttttggtgt
     5761 tgaaacccaa aagatcattt cagaaggtac tcgctatcgt ttagtcggaa aagagacgga
     5821 attagtagca gatatgattt tttgtgcgac tgggagacag ccgaatacag aatctttagc
     5881 acttgagcaa gcgaatatcg tctttgataa acacggaatt gcagtcaatg attatctgca
     5941 aacgagcaat ccaaaaattt ttgcgtgtgg agatattgtt tcaaggaaaa ccccaaaatt
     6001 gacaccagtc gccacttttg aaggaaatta tgtagctaag cggataacgg atgcaacaag
     6061 cgaacctatc aaatatccga ttatacctac gatcgtctac gccagtccta aacttgctga
     6121 agtaggagtt acaaaaagtc acgcctcttc gtcagatcaa gtggtagaga tggatcttac
     6181 cagttggttc acctatcatc gtgtcaatga accagttgct aaggctgaat tgacctttga
     6241 ccagcaaaat tatttgattg gtgatgcagt gattagcgag caagcagacg aattgatcga
     6301 tgatttgaca ctcgtcatca atcaaaaatt gactaaaaaa gagttggata gctatatcat
     6361 ggggtatccg acattggcaa gtgatctctc ctatttattg aaataatcag catgataact
     6421 aaagcgcttg ttgctttttc cttcttgtgc tacactttaa aaaatgaata cctgtttctg
     6481 gggatgtcgt agacgacatg agagtaagtt gtgaacttag acccattgaa cctgtcagtt
     6541 aatactggtg aagggagaaa catagcagac gcttgaagcg ggttactatg tcgtgcccat
     6601 ttcaagcgtt ttttgttatt catattagaa gaaaggaggt aacaaaatga agaaaaatct
     6661 ttatccagca gtcagtatgg cattcatttt aattatttgg cagattgttg tcatagtttg
     6721 gaaaatacct gcctttattt tacccggacc tgctgctgta ttttctgcat tagcggcaga
     6781 tgcacaagta ttactttccc attctgtcac gacattaaat gaagcagtgc ttggtttggt
     6841 aatagctagc gttctttctt ttattactgc cttggcaatg gattattgga agtttttaga
     6901 aatgtctttt tatccgttac tagtgatttc acaaatgttg ccaatcatgg tgttagggcc
     6961 attacttacc ctatggtttg gtttcggtat gcttccaaaa gtgatccttg ttgtcttgat
     7021 aagctatttt ccgatcgtag tttctttttc ggatacattg aggaaagtat caaaagagca
     7081 aatcatcttt ttgaaaacga tgggggcaga tacagggaag atttatcgaa tatataaaat
     7141 accagcgggt ttatccggct tcttttccgg tttaaaagtg gctgctactt attgtgtcag
     7201 cggagcagtc gttggagaat ggctaagcgc tcaagcaggc ttagggtatt acatgatacg
     7261 cgtaaaaaac agctaccaga tcgataaagt ttttgctgcg atcatttgtg tcattctatt
     7321 gagtttattg ctgaatggcg cttgttcatt attgaaaaaa gggtattatc gtatgcttta
     7381 tattttttaa gagaagggga tcaaatgaaa aaattatggc ttttattacc gctactgttg
     7441 cttttatccg cttgtggcac tgcaaaagaa acaagtagca aacaagaaat aaaggatttg
     7501 aaaaaagtga cacttgtttt ggattatgta ccgaatacta atcatactgg catctaccta
     7561 gcaaaagaaa aaggctatta taaagaggct ggtttaaatg tccaaatcat cgaaccagga
     7621 gataattcga caagtattgg tctagtaggt gcggacaaag cacaatttgg tgtaagttat
     7681 caagaagatg tcacttatgc tcacgcagat ggacagaata taccagtcaa agcaattgct
     7741 acagtgatca aacataatac ttctggattc gccaccctat cagacagtaa catccattca
     7801 ccaaaagatt ttgaaggaaa aacatatgca ggttggcaaa gtccaagtga agaagctgtc
     7861 ttaaaagctg tgatggaaaa agacggcggg gacttttcaa aactgacaat ggtaggaagc
     7921 aatggagaag ggccagaaag cttaggaaaa tcctcagata tccaatggta ctttgaaggt
     7981 tgggatatga tcaaagcaaa agaagcgggt attgaactaa actatatccc attgaaagaa
     8041 ttagatgaac ggttagatta ctatactccg gtaattatta cgaatgatca actgatcaaa
     8101 agtgatccag aattggtaca gtcttttatg gatgccacga aaaaaggcta tcaggaagct
     8161 attaaggatc caaatgacag tgctaaactg ttgcaaaaat atgcaaaaga aaatgatcgg
     8221 acgtttttag aagaatcaca agcattcttg tcaaaaaatt atacggatga tcctgagaat
     8281 tggggattga tggaagaaaa agtttggcgc aattatacag cttttatgca ggaaaacgga
     8341 ttgatcaagc aagatgtacc ttcgcaagaa ctattcacta atcagtttat aaaataggag
     8401 tgatagatat gtcaatccaa atcagccact tgaatgtagt cattgaaaac ctgaaaatat
     8461 tagaagacat ccatttcact atccctaaag atacctttac atcgattgtc gcgccaagcg
     8521 gagccggtaa gtcaacattg ctgaaaactt taacaggagt ccagcctatg acttctggaa
     8581 cgatcaaagt agacgatcaa aaagtaactg gtctccatac agcatttagt tatatgccgc
     8641 aagaagatat gttacttcct tggctgagcg tctatcaaaa cgttacgtta tatcaaaaaa
     8701 tcaatcatct aacaatcaat gaagaacaag taagggatta tctggatatc tttgggttaa
     8761 acggctatga acattttttg ccggaacaat tatctggcgg gatgaagcag cgaacggcct
     8821 tgttacgaac aatcatgaat ccttcttctt acttgcttct tgatgaacca tttggagcgt
     8881 tagatgctat gaccagaggg cagatgcaag actggatgtt gaagctgcct aaaaaagcaa
     8941 agcggactac tttacttgtg acgcatgata tcgaagaagc aatttattta tcagacagga
     9001 ttcttgtgct ttccgcccgt ccggcacatg tgattgctga gattcaagtg cctgaaaaac
     9061 gacggtcacg tgaatggcta ctgcagcaat cagagttgaa gcaaacgatt tatcagttat
     9121 tggcaggtga attagatgtt aagtgatgct cattgtcatt tagatgggag tcagagttta
     9181 gcactccttc agcaggaaca cacgattttg acgatcatca attgtgattc gccagaagaa
     9241 tggaaggaaa acagacagct tgcagcaagt aagactcaag ccttaagtta cggtatccat
     9301 ccttggaaag cagatagcta tacgtttgaa caagttgagc cttttttgaa aaaagcaagg
     9361 atcatcggtg aaatagggtt agataatatt tggacgaatg taccgatgac tacacaaaaa
     9421 aaagtatttg agcgacagct tgcttttgca gccataaatg agaaacctgt tgtactgcac
     9481 acaaaaggat gcgaaaaaga gatcttaaat tatatccaag cttaccctaa tcactatttg
     9541 atccattggt attcttcttt ggactatcaa caagactata ttgatttagg ctgttatttc
     9601 agcattggtc ttgatttgaa aaagaatcca gcagtctggc aactagctaa agcagtccca
     9661 atcgaccact tacttattga aacggatgga ctacatgcag cagagtgggc tttagggggg
     9721 attttttcag aaaaagatta tgtctcactg cttgaagaac agttaaagac aatcgctgag
     9781 atcaaagagc tatcagttga agaagttaaa aaaaatactt atcaaaactt ggaacgtttc
     9841 attagattag gtaaataaaa aagagatgtg acacaactag tgtcgcacct ctttttggct
     9901 ttctttgtat aaaagtaaac tgtttgatta ataaatgaat cttagtacca accgtttgct
     9961 tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg aagtaacata ttgttctgct
    10021 actctttctt ggtttgcagc agagtagtca ccatttaagt aagaagaatc taattggtaa
    10081 cgtccgatgt aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt ttgtgcgatc
    10141 cattcttttg cagagcttgt gcttgctgga gtagcagcag tttctgttac agcaggagca
    10201 ggttgtgttt cagcaacagg cgctgcttgt ttttccgttt gaaccgtttc ttgtacaaca
    10261 ggttgttcag cttggactgg tgcttcttga acggctgctt gaggttcagc agctgcttgt
    10321 gcagagcctt ctgttgggat tgttaattgt tgtcctgagt a
//
LOCUS       DADVXB010000098        10305 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.100, whole genome shotgun sequence.
ACCESSION   DADVXB010000098 DADVXB010000000
VERSION     DADVXB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.100"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(56..1564)
                     /locus_tag="KB902_001985"
     CDS             complement(56..1564)
                     /locus_tag="KB902_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBB6808778.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            1723..1914
                     /locus_tag="KB902_001986"
     CDS             1723..1914
                     /locus_tag="KB902_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808779.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            2117..3034
                     /locus_tag="KB902_001987"
     CDS             2117..3034
                     /locus_tag="KB902_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBB6808780.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            3027..4100
                     /locus_tag="KB902_001988"
     CDS             3027..4100
                     /locus_tag="KB902_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808781.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            4248..4766
                     /locus_tag="KB902_001989"
     CDS             4248..4766
                     /locus_tag="KB902_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808782.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            4747..5139
                     /locus_tag="KB902_001990"
     CDS             4747..5139
                     /locus_tag="KB902_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBB6808783.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            5215..6150
                     /locus_tag="KB902_001991"
     CDS             5215..6150
                     /locus_tag="KB902_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBB6808784.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            6283..7062
                     /locus_tag="KB902_001992"
     CDS             6283..7062
                     /locus_tag="KB902_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6808785.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            7055..7372
                     /locus_tag="KB902_001993"
     CDS             7055..7372
                     /locus_tag="KB902_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6808786.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            7616..9226
                     /locus_tag="KB902_001994"
     CDS             7616..9226
                     /locus_tag="KB902_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6808787.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVALGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            9383..10231
                     /locus_tag="KB902_001995"
     CDS             9383..10231
                     /locus_tag="KB902_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6808788.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         3241 a         1803 c         2080 g         3181 t
ORIGIN      
        1 gaaactatcg attaagctaa tagtttcgtt ttcaacattt ataagtaaac tttttctatt
       61 ggtaatatag attttcggaa gggtagacag gtgcgcaggt aatatcgatt cctagttttt
      121 tcaatgtttg ttcatcattt ttattgacca tcacagtaga gtgggcttgt gctccctcaa
      181 gttcagctag tttatcataa gcaacttgag cgattggatt cgttactgca ctgattgata
      241 aagcgatcaa gacttcattg atgcttagtg catccaaaga ggaatgaagt gtctttgatt
      301 tcaatccttg tattgtttca agaactaatg gtgacaataa aggaatgtca tctgcgatat
      361 gggctaaatg ttttactgca tttaagataa ctgccgctga cgcatccatc aatgaacttg
      421 tacgcccggt aatgatgact tcatctggta attcgattgc aatcacagca gaaggatctt
      481 ttgtaggact ttgcgcttga atcttatctg catagtcatg ggcagggact accacgtttc
      541 ggtcttcagg acgtaaaccg acttcttcca taatcagttt gattcgatta actgcttctt
      601 cgtcgatcaa tccttttttg aagtcgcatt ctgtttggaa ataacgacgg atgatttctt
      661 gtttagaggc ttcttggaca acggtatcat ccacgatccc aaatcctaca cgattcacac
      721 ccatgtcagt aggagattga taaacagatt ctttaccagt aattttttca ataatacgtt
      781 tgattacagg aaatgtctca acatcccgat tatagttcac agctacttta ttgtaggcat
      841 caaagtggaa ggaatcgatc atattgacat cttttagatc gactgtggct gcttcataag
      901 caatgttcag cggatgtttc aacggaacat tccatactgg gaaagtttcg aacttggagt
      961 aaccagctgc atgtcctttt tggctttcat gatacagttg gttcaagcaa gtagcgagct
     1021 ttccacttcc tgggccagga gctgtcacta caacgattgg tttagttgtt tcaatatact
     1081 cattttttcc aaaaccatct tctgagacga ttttttctac gttgactgga tagtcttcga
     1141 tttctgagtg tttatagacc ttgatgtttc gtctttctag tttattgata aagactttcg
     1201 tggcaggctg tccactatag cgagtgataa cgacactgtt gattaataag ccataaccac
     1261 gtaattcatc gattaaccgc aagatatcca tatcataagt aatcccataa tcaccacgga
     1321 tcttattacg ttcaatatct ccagcataga cgcaaatcag tatttcagct tgatctttca
     1381 atttttgcag caatttgatt ttcgcatctt cttcaaatcc tggaagtaca cgtttcgcat
     1441 gcttgtcgtc aactaacttc ccaccaaatt ctaaatataa tttgtcatag tggttcactc
     1501 gttccaaaat atacgctgac tgctcttcaa tatatttttc tgaatcaaaa ccaatttttt
     1561 tcactaggtt ccctccttaa gtactaaagc attttttcat ttttttgagg attcgtcaac
     1621 tggaagagcg aaattcctca aaaaaacaaa gaaaatggtt taaaccaact tgtctagata
     1681 gttattcatt ggtatgatag tttttgataa ggaaggtgct acatgaaaaa aagacagaaa
     1741 aagaaaaacg catataaaca ctatatccgt tcgattttta ccggttatga aagaatgctt
     1801 gaagatcccg aattggaaca attgacgttt acttatctaa acgaagaaac gcagctaact
     1861 cgtgatgagc atcagcgcat tcatttcaca acaagagatc tgcctagtaa ataaaaaata
     1921 agataaaggt catcggattc gattctgtcc tatcagatgg aaagactagt tgatcgaaaa
     1981 aaaggctgta ccaaattttg gtgcagcctg ttttatggag cattgcccgc tcttttttat
     2041 aacaattttt tacagaaaat ggtactattg aagtattaat aagtgaaaaa cagatgagta
     2101 agaggaggca agtagtatga aagagccaga tacaaatgca aattatgagc cagacgaact
     2161 agaggagacg aacgcggatc aggatacagg acaagaatcg tcttcttttt acgatatcaa
     2221 agaaaaagca agcatgaatc tttcccaatt attagaagac ttacaggctt ttgaaaaagc
     2281 tgtccgcgaa gaagatatcc ctgagatcta ccgtttatac aatggccgat tgaatgaaga
     2341 attaaaaaga agctcaaatg aaaatcacga gatcgatcaa ttgctgatgc gtaagatcca
     2401 tgatcgtttt ttacaggaat ttccttttat ggaacaagta gaaaacatct cgccaacgat
     2461 gagctattac aaaatcggca cttattacca tgatcggccc acggtcggta ttgatgcaag
     2521 tctgccagaa atttttgttt tgcctaagat cgatgaagag tgggagaaat attcccaacc
     2581 ggagtcaacg gactatgaca aaaaaatcaa tgagctagac gcaaaggtga tcactgctca
     2641 gacagaaatt gaacgtttag atgaacaaat aaaagaaatc aatcgacaaa tgactgattt
     2701 gaacgacaat aaaggattct tgaatcgtaa aaaaatcgag gaagaaattc aagaattaga
     2761 gaagaagaag caagtactat ctaatgaaaa attaggctgg cttccttata ttgagacgcc
     2821 tgaaacaatc cagcagcaaa aagaagcatt gaagcaagaa gcaagagcag accagcttcg
     2881 tgcagccatc gtagaaaaag aacaaaggca aatcagacgc tatttcggta gcaaagaggg
     2941 attcggtcaa gcaatccatg aattcttgat gaattatctt ggcaatgaga atcctaataa
     3001 tcaatctaat gaaggaggtt ccgagtatga atgaacacga tgaagcagaa tggacaaaaa
     3061 atgaagaaca aacagaagat catgaagaaa cgaacacttc attggaagaa caaacaagta
     3121 atcctctgga tgacacagaa gaaatcccta tgctagagga aacaaaaata catgaaaaag
     3181 aaaaagtaac tccgacgaat acgaatactg cagaaaacac ccatgcttac gaaataactg
     3241 aaaatcccgg gtatttagaa ggaaaagagc aagatcatca agatatcgtc agtttgattg
     3301 aaacagcgga agcagaatta gcggatttac gtatgagaaa agatttgatc gaatcagatt
     3361 ttccacaatt attagaatca tatgatcgtt ttatattgaa tgaagaacca atctccacga
     3421 tcggaaagac aagcctgatc gaatacttca cgtatgaatt actgaaaccg ttgaatgata
     3481 ttggtctgga acggtcaaat tcagcttatg acacatggaa aacaagacat ttttcgatca
     3541 attatacgtt gaatggacaa aacgaattag tcttttcctt tgtattaccg accatcgatc
     3601 aacgatacca agtggaatcg atgagtctcc taaacgtatc accagagaca atggaaatca
     3661 atgtccaaga tgaccgggtg ctttctttga tccgacactg gtcagtggat cgagtattct
     3721 ctgcagggca gatcacgata ttcaatcaca aattgaatca attattagcc catgcaagaa
     3781 cacttggttt taccgttaat cagacattac tagacaatac gaagccactt cgtttgaatc
     3841 ttcagagcga atttgaattg acgaatgaag tattggatga tatttttatc gtggcaatga
     3901 aaaatccatc ctacgatatg gaaaagatca acgaaactac ttatcaagta cgattagata
     3961 aaggacagtc tttaacgata acaacaaacg aaaaagatca aacagtcttg tcgatctcat
     4021 ctggagacta cccacgatct gtcattgatt tctttatcaa ttacgaattc ttggtcccat
     4081 taatggtgag aaagtcctga ttggataagt tggattacca gatgtcattc agataattct
     4141 gttccaaagg acttgcggca gttatccaga ataattgtca caagtctttt ctgtatgtac
     4201 taaatggacg tgaataactt gctgatgaag gagggatttc attaggaatg tccacaaata
     4261 aaatagcaca gcttagctta ttgtctgctg cttgtgtagc aggtaggatc gcttttcaat
     4321 ttattccgaa tttccagcca atgactgcta tttttttatt tatagtactt tacttaagct
     4381 taaaagatgc gttaattgtc atgagtcttt ctattgcgat cagcagtttt tattttggtg
     4441 ttggaccatg ggtcatcggc caatggatca gctatactgt tgttctgagt ttgttttcaa
     4501 tcgtctgctt gagaaaaaca gtgcaaagga atctatggtt aaagggagtc tgtttttttc
     4561 tggcgggcat ggtttacgga ataggtatga ccgtttttga tacgctgtta tatcgtttgc
     4621 ctcaaccttg gatctattac cttcaagggg tgtcgtttga tttgatgcac agtataggca
     4681 atgttgtgtt ctttcttgtt tttctgccag tcgtcaaacg tttttacaat cattcaggag
     4741 gaaaaaatga aaaaaataat ttatagtttg cttgcaatga gtgtcagtat actcattttg
     4801 acaagttgca gtacaaccta tacacaatcg gcttccaacc aaaaggagga agtaaaaaca
     4861 tcgcaaaaag caacaatcac gttacaagaa aatggtcaaa acttttcgga aaaagaagtg
     4921 gtcttcaaaa aaggcgatga tttactgagt attttgaaac gaaattttga agtcaaagaa
     4981 gataacggct tcatcacttc gcttgaaggg cactcacagg atgagaaaaa tcaactctat
     5041 tggatgttta ctgtggacgg gaaaagtgct actactggtg ccaaagagat caaattgaat
     5101 gatggacaat cggtcatttt caatttgtct aaactataag tttcataaaa aactgttaaa
     5161 gggcgaatat tgccataatt cagtgagttc agttgatgaa agaaggaaaa taacatggaa
     5221 aattttaaaa aaagcggaat gttttccgta attgctgctc taggggctaa tattctagtt
     5281 gctatcagca aatttgtcgg ctatgcaatc agtggcagtg ccgccatgct aaacgaaagc
     5341 atccacagta tcgttgattg cagcaatcag attttgctgt tattcggtga taaacaagcc
     5401 aataaaggac agagcgagtt gcatcaattt ggtgaaggac gagcaaaata ctttttcagt
     5461 acaatcgtcg caatgatgct tttcttcggc ggtggggcac ttggggtgat ggaagctttt
     5521 gaaaagttga cgcatccatc ccatgaagtg ggtaatccga tcattgttat agcaatactg
     5581 ttatttggtt tggtaatcga aggaagttcg ttacgcgtgg caatgaaaga aatcaaagaa
     5641 ttgaatactg aaaaactttc cacgatgcgc tttttgcgcg aaagtcgaca cagtgaaata
     5701 ctgattattt ttacggaaga cttgtgtgct gtaatcggtt tggtcttggc tttagcagga
     5761 acaatattga cttatgcaac cgggattgct gcatttgatg cgatcagcgg attgctgatc
     5821 ggtttcttgc tgatgggagc cgccattttc ctagcaaaag aattttatag tctgatcatc
     5881 ggtgaaagcg tgacagcaag cgatttatca aaaatcaagt tagcttttga acgtcctgag
     5941 atcagtcggc tgatcgatat aaaaacagtt catttaagtc caacggagat tttagttgca
     6001 gcaaaagcag atatcgttgg taacaaagag aatgaagctt actcggtcat caatgatatt
     6061 gaaaaaaata tgcgtcagtc tcttcctgac aagaagatgt atatatacat tgaaacagat
     6121 aaatatgacc caaattattc tcgtaaataa aacgtttatt catgaattga agcaaaaatg
     6181 agaaaaatat aatcttgttt ttaaataaaa cggctacaat ttagcgaatt tatgttacaa
     6241 tgagtccgct gtttatttgt tgtaattaaa ggagatattt taatgaacaa aaagaaaagt
     6301 gcgccatggc ttcaagcttt gcatgcagtg atgccacttt gtataagcta tataccagta
     6361 ggattagctt gcggagtatt gttgcaaaaa gttggatttg atcctctctt atcaggactg
     6421 ttatcgattc tggtcttttc cggtggcgcg cagtttttag ttgcatctat gcttacgacg
     6481 caagcatcat ttgcaacgac attattgatg gttttctttt tagaattacg ctatacatta
     6541 ttaggagcaa gtcttgccgg ttttatgaaa aaagaaaagc ggacgttttt ggctgtcttt
     6601 tctcaatcac tgaatgatga aaactatgcg gtgaactact taaagttttc aactgaccct
     6661 tcctggaata aaagaaaggc tttatatgtc aattggttct caatgactgc atgggccggt
     6721 agcaatatga tcggtaattt tttcggctcg gtgattcgag tagatgctga ccttgtccat
     6781 tttgctttga cggccatgtt cattttcatg tttatcatgc agatgaaaag cgcactactg
     6841 atctttacag gtttattctc aggcgtatta ggggtcgtat tcatggtatt attccaaaat
     6901 actttcggat tgattgcagc aacagtcatt gcttcatttg ccggatttat gctggagaag
     6961 gcattcaaaa aagaaaaagc taagaaacta agagaccgcg gtaaagatgt caatgagccg
     7021 ctcttcaact tcccggaaca ggaggccaat caccatgact aaactatatt tgctactttt
     7081 agttgcttgt ctgttcatcg tggcatatat cccgcgcttg ttcccgatgc tttattttac
     7141 tcatcgaaaa gtgccatcct ggttcagtga ctggatgaaa tatgtaccgg tggcattatt
     7201 tgcggcgtta gcttttaaag atgttttcat tactcatgaa catctggata ttgcttggaa
     7261 tatcaaaata gctgcaatga ttctagtagc aggcgtggct tacaaaacac gttcgatggc
     7321 gttgtcagtt ttgacaggac ttgcgtctgt ctttttgctg tctatgcttt aaactgtttt
     7381 attttattaa aaacagagat tgcgacataa gttgttcaaa ctgatctatc cgaactgcat
     7441 ttgcaacagt caattctgga tgcaagttta ttcgtaggga taaaaaagat tagtgttggc
     7501 ttatgatgca agctcttttt tattttagga attagagagg gatttgtcct tctatgattt
     7561 tttgctataa tagggaagat gtttatttta tgaaagaata gttgagggaa tttaaatgaa
     7621 taaaaaattg atgcaaggaa cattttggct aacctttgct aatcttctat gtaaagtttt
     7681 aggggtagtc tatttgattc cctggctaag tatgatgggg aacaatcaag atggtatgct
     7741 tgctacgaca ttgtataatg ttggctatct tccttatgga ttgttcctga tgcttggtac
     7801 agtcggattt ccaaatgcga ttgcaaaaaa agtagctgta gccacaaaag aaggagataa
     7861 cgctgcttgt cggctgattt ttagaagtac gatcaatatc atgtttgtca tcggtatcgc
     7921 ctctgctgca ctgatgtatt tatttgctcc tttactagcc ggaatcagtc cgattgctaa
     7981 cgttaataat gggatactag ctatcagaag tttatgccca tctttgattg ctatcccaat
     8041 tcttagtgca atgagaggat atttccaagg aaaaaatgat ctgcggcctt atggaacttc
     8101 tttgattatc gaacaggctg tgcgagtgat cgttatcttg gctggtactt attacttgcg
     8161 cgtattgact gacggaacca tattagaagc tgtattgatc agtacagtcg cttctttctt
     8221 cggtgggtta gctgcgatta tccatatgta tatcgtcgga cgcagaaaag acttcttcga
     8281 acttaaagat tttttgattt ccagccgtta tttcgaaaga gaaaaccgat ctgcctctgt
     8341 ctctatcatt cgggaaacac taccgtttat ttttgtcggc tcagtcatta ctatcgttca
     8401 aatgatcgac caagtaacga tgaaaccact gcttcacttt ttccgtccag agatcgcaga
     8461 tcagcaactg gaattcttat tcagccgtgc ttctgtcaat ccaaataaat tgacattgat
     8521 cctgatctcc atggtaggaa cagtagctat aagcagcttg ccaatattaa gcacgatgaa
     8581 gaaaaaagat cggatacaaa tcgaaaaaac agtaggagat agtttttcga ttgcgttatt
     8641 gattcttctt ccttcattga ctggaatgtc tttattagct ggaccactat acacattgtt
     8701 ttttggctat gatcctgaaa gtgtcggata tttccaaatg gctttgctag cttctttgtt
     8761 tttctcttta ttcacgatcc tatctacgat gcttcaatct ttgaatcacc atcgttttgc
     8821 gatccgatta actgtagaag caattatcct gaaagtcatc ttccaagtaa tcggattagg
     8881 attagttggc ggatacggga tgagcttatc aaatggctta gcattcggta ttgtctttgt
     8941 tcgcggctat cactttatgt gcaaagaata ccgaatagca cctttagcaa agatcagcaa
     9001 ttttttctta aaaactttcc gctccaccct gattatgctt gcagtatgtt ttgccgtttt
     9061 ctttttgctg aatcagcgat tgtcaatgga atcaaaaagc tatgcaatga tttattgtgt
     9121 ggctttagga agtattggcg gcttagtatt tttattttct caattcggaa aaaatgggtt
     9181 tcgaatgttg aaaaatgtta aacatcatag cagaagcaaa gaataggtta actaatcgtt
     9241 ttttgctgtc acttgaaaaa cggcaactcg tatgattacg cttgtcgttt ttctattttc
     9301 caattttagt ttcatatcta atcttactta tgatatagtt ataaggtctg gaaaaattct
     9361 ttgaaacgag gaaattaaac acatgaaact tgcagtagtt acagatagtt cggcatatct
     9421 gccggaacgt atcaagaacc atcccgactt attcgttatt ccaatccctt tgattatgga
     9481 tgggaaaatt tataacgaag gaatcgatat cgaagcggat gaatattatg gacttttaaa
     9541 aaacagtaaa gattttccta ctacttcaca acctgtcgta ggggaagttt tgggtttata
     9601 tgaggaattg aaagagaaag ggtatgacac gattttaagt atccatcttt cttcagggat
     9661 ttctggcttt gtcaacacat tatttgcgat gaaagatgac atcagcggag taacggtcat
     9721 tccttatgac tctaagatca ctagtatgcc gatgggacac atggtagaag ctgccttaga
     9781 cttaaatgat gaaggtcagt cccttgatga aatacttgca catatcgatc gaatccgaga
     9841 taatacctat gcttatctga ttgtagatga tttgaacaat ttagtacgag gaggacgttt
     9901 gacaaatggt gcagcgctga ttggcagctt attaaaaatc aaaccgatcc tgacattttc
     9961 tgaagggaaa attgttttat tcgaaaaaat ccgttcaagt aaaaaagcat ttgctcgagc
    10021 tgaagaaatt attggtagaa gaaataacga aatacaaccg ccagtcaaac tttacgtgat
    10081 acatgcaaat aatttagaag tagcgattgc ggagaaagag aaattgcaga aaaaatatcc
    10141 aaatgcagaa atcgaaattg gtcatttcgg accagtcatt ggtacacatt taggtgaaaa
    10201 agccatcggc attgccattt cagcgcaata attcctttta ttcaaaaaac ataccaaaaa
    10261 tattggctct ttgtcaaatg atgttggtaa agagaaatct tagaa
//
LOCUS       DADVXB010000099        10003 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.101, whole genome shotgun sequence.
ACCESSION   DADVXB010000099 DADVXB010000000
VERSION     DADVXB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.101"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            39..710
                     /locus_tag="KB902_001996"
     CDS             39..710
                     /locus_tag="KB902_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6808789.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            769..1209
                     /locus_tag="KB902_001997"
     CDS             769..1209
                     /locus_tag="KB902_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808790.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1221..1889
                     /locus_tag="KB902_001998"
     CDS             1221..1889
                     /locus_tag="KB902_001998"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6808791.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1953..2576
                     /locus_tag="KB902_001999"
     CDS             1953..2576
                     /locus_tag="KB902_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6808792.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2632..3018
                     /locus_tag="KB902_002000"
     CDS             2632..3018
                     /locus_tag="KB902_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBB6808793.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3231..4622
                     /locus_tag="KB902_002001"
     CDS             3231..4622
                     /locus_tag="KB902_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBB6808794.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5233..5601
                     /locus_tag="KB902_002002"
     CDS             5233..5601
                     /locus_tag="KB902_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBB6808795.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5781..6722
                     /locus_tag="KB902_002003"
     CDS             5781..6722
                     /locus_tag="KB902_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBB6808796.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6791..7522
                     /locus_tag="KB902_002004"
     CDS             6791..7522
                     /locus_tag="KB902_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBB6808797.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7666..9846
                     /locus_tag="KB902_002005"
     CDS             7666..9846
                     /locus_tag="KB902_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBB6808798.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9866..>10003
                     /locus_tag="KB902_002006"
     CDS             9866..>10003
                     /locus_tag="KB902_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6808799.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HL"
BASE COUNT         3335 a         1711 c         2168 g         2789 t
ORIGIN      
        1 tatgctattt taaaaatgat gaaaaaaggg ggagaaaaat gaatttttta gttgttttaa
       61 aagatactct gattgagcga tctacatttc tatatgttca attgcaggaa aataaaacat
      121 tgctgcattt ttcaccagag ttccatctag aggggctaac attaggagaa atctatcaag
      181 cagaagggct gtcggctgtt ttgcactttt ttaaggtaga attggaatta ccagtaaaag
      241 attatatcga gctttctctt gaatcttggg atcgagcagt ggttgaactg tttccagaag
      301 gtttaatgat cgatacaaac gatgggaaga tccatctgac tgcagcagaa ctgcaaaaac
      361 aaatgcgtta tcaaatagat gacgaaaatt ctttttctat ttttagacgt cagcaaaaga
      421 ttctaaaaag ctttttaaaa gtgatcagta aaaaacggaa tctgatcaaa acgacacagc
      481 tgttgaaaaa atatccaggt ctgcttcaca cgtctattca atttcctcaa ttgattacga
      541 tgatccatcg ttttatacgt atgcaacagc taccatctaa gaagctgttt cttccattga
      601 cggacacatt tcgagtagtc aacagagaag ataaaaagaa agtgattgtg attgacttta
      661 ccagaaatcg gaatgtcctt caccaagttg caatggaaaa ggccaattaa ggctttttct
      721 ttttggattt ttttgtcata ataaatatta gatgatggag gagataatat gatgcaaaca
      781 tggttagaaa ggctaatacg atttcagcag aactatcaca aacttatgca gggaagatat
      841 gcgaaatttg atcagttgaa tcgcggtcta ttgatcgctg cgcttgtctt tagtttgcta
      901 agtcgttggt tgccctatag aatcggacaa ttgttgttca tcgtcttttt cggatggatg
      961 atatttcgtt tcctatcaaa aaaaatctac cccagactaa atgagaatca acgttatttg
     1021 aaatatcttg atagagtcaa agaaaaatat catcagataa aaaacaaaaa gcaagtcaaa
     1081 atggatcgaa aaagttatac tttttttgag tgcccgaatt gtcatcaaaa gcagcgtgca
     1141 cctaaaggaa aaggacgaat acgtgtgaca tgcaaaacat gtggtataaa attcgaaacg
     1201 aatgtttaag ggagaaaaga atgaaattag tattattacg tcatggcgaa agcgaagcaa
     1261 attttgaaaa ttactggaca ggatggctag atgtcgcctt aacagaaaaa ggaaaagaac
     1321 aagcagcagt tgccggtcaa aaaatgcttg aagccggact tcaattcgat gccgtttata
     1381 cctctgtttt gaaacgtgcg attcttaccg gacaagtcgc actagaagaa atgggtcagt
     1441 tatggcttcc tataataaaa acatggcgtc taaatgaacg gcattatggg gatcttgtgg
     1501 gtaaaaacaa agataagatg aaagaaatat acggaaaaga tcaagtaaaa acatggcgca
     1561 gaggatatac ggaagttccg ccgttaaccg cagaaaatag atttgaccgc agatatgatc
     1621 acttggatcc gcatttgatc ccatacggag aaagtctgga aatgacagtg aatcggatca
     1681 ttcccttatg gcaagatcat ctagcaccaa aactaaaaga tcggcaagat ttactagttg
     1741 tgggtcatgg taatagcatc cgagcactga caaaatattt agaagatgtt cctgaagatc
     1801 aaatggatac gatcgatatc ccaaatgcac aaccaatcca gtatacatta gcagatgatt
     1861 tgacaattct ggacaaaaaa atactttaaa gaacaccttt atctaaaagt gagagataga
     1921 aaaaagaagc aaaggaatgg aacaaaagga acatgaaaaa ttatatatgg gactttgatg
     1981 gtacattgtt tgatacgtat cccgcaatgg tagatggtgc atggcaagca ctaaaagatt
     2041 ttggtatcag tatggacaaa aaagaaatct acttcaaaat gaaaaagtat tctactagtt
     2101 atttgatcaa tgaatcaaac ttgaatgcca gagagtttaa tgaattattt caccgatatg
     2161 aaaaagaaag tacggaagtt tcccgtccat ttccagaaac gaaacaagta ctggaaatgc
     2221 taaaagacaa cggcggtcgt catttcatcc tgacccaccg tttgacagaa tcaacatggg
     2281 gcctgttaaa agaacatcga ttggcacatc tgattgagga agtagtaggg atcgatcagg
     2341 actttcctcg taaacctgat ccagcatctt taaattattt gatcgatact tttcatttag
     2401 aaagaacaga cacgatgatg atcggcgatc gtcgtttaga tatcgaagca gggaaaaatg
     2461 caggagtcgc tacttgtctt tacgacatcg atcattttct gggtgagatc ccggcagatt
     2521 atgtggtagg aaatctgaat gaaatcctta ccttgcagag catcattaaa aagtagtatc
     2581 ccctttcaaa ggagatatgt tataattttc ataaaggagt gataaaatta tatggaaatc
     2641 agaagacaaa aagaagttgt agaagcattt cattatgata tgagattgcc gaaccaagaa
     2701 gtagaaacag atttgaaagt aggcttctcg cctttaaaag aaacgatcga aaactatccg
     2761 aaagaacata gcatcgtagg agcacgctta gagttccgtt tagtgtttga tacatatgtt
     2821 ttatctggaa gtgtgagtca gatcaatcat atcctcaatc ggaaaattga aggtcaaaat
     2881 gatgtcacac aagaagaagt ggacgagcta gtagcaccgt tattcgatat cgtacgccga
     2941 atgtcttatg aggtgacaga gatcgcctta gatcagcctg gggtaaaatt gaattttcaa
     3001 tcagaaaaac aagaatagac agtaaaaaca tacctgcgat agattaaagc tatcacaggt
     3061 atgttttttt attactaatt gtaagcaaaa agaatgtcat ttcgataaaa atcgtctaaa
     3121 atataaaagt cactgaaaaa aattttttca ggaggatggt tgaagaatca ttctcgggaa
     3181 cctttacttc cttcgatgga cttgtcatta ataatatgag gaggagaaaa atgacaacac
     3241 tcatcacagt tttagtggtt ctagtttttg cggcattatt atatgtgttc tatcgtatgc
     3301 aaaagcgcca tacaaaattt tcaacacgcg tctttacagc attaggagtt ggtatcgtct
     3361 ttggcggtct gcttcaattg atctttggtg tagacgacaa agtcgttact caatcaatgg
     3421 aatggatcgg gattgtaggt caaggatatg tatcattctt gcaaatgcta gttatgcctt
     3481 tagtgtttat ttcgatcatt ggtgcattca caaaaatgaa agtttctgaa aagctaggga
     3541 aaattagtgc gactgtattg acttctttac ttggaacaac agctattgca gcattgatcg
     3601 gaattggttc aacaatgctg ttcggactcc aaggagctaa attcacacaa ggagctgcag
     3661 aaacagcacg aatctctgaa ctggcaacac gtcaggaaac agttgaaaac ttatcgattc
     3721 cacagcagat tttatccttt atccctaaaa acgtttttgc tgatttagca ggtagtcgtg
     3781 caacaagtac gattggagtc gttattttcg cggcatttgt cggaatcgct tatctaggcg
     3841 tgaaaagaaa agcgccaaaa gaagcagcat tcttttcaga tttagtcgac agtctgtata
     3901 aaatcattat gcggatcgtg acgcttgttt tgcgtttgac accttatgga gtatttgctt
     3961 tgatgacaaa cgttttggca acaagtgatt ttgcagctat cgtcaattta ggtaaatttg
     4021 tcgttgcttc ttacgtagca ttgcttgctg ttttgattgt ccactcactg attttgattg
     4081 gtgcaaaagt caatccaatc aactatttca aaaaagcctt tccggtattg agctttgcgt
     4141 ttacttcacg ttcaagtgct ggagctttgc cattgaatat cgagactcag acaaaagctt
     4201 taggagtaga tgatgcaaca gctaatttct cagcaagttt tggtttgtct attggacaaa
     4261 acggctgtgc tggcgtttat ccagctatgt tggcaacgat cgtcgcacca gcagctggag
     4321 tgaatgtctt tagtttggaa tttattttga tgcttgtggc aattgtaaca atcagttctt
     4381 ttggtgtagc tggagtcggt gggggcgcaa catttgcttc actgatcgtt ttaggggcaa
     4441 tgaacttgcc agtagcaatc gttgggttag ttatctctgt tgaaccatta atcgatatgg
     4501 cacgtacagc agtaaacgtc agcggtagca tggtagctgg tatcgtgaca agtgcacgca
     4561 tcaaagattt agatcgcgat gtcatcaatg atgattctaa agtgatcgat gtgaatgcat
     4621 agtcaaaaag aggttgtgat agaagtggtc agctttaaga aataagaaga agtttcctaa
     4681 aaatagtttc tcaaattttt gtgaaatttc ggcttatttc cgagaagcta cttctgaaac
     4741 accgtgaata agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca
     4801 aaaatagttc ctcatatttt acgtttggtt gagcttatta ccgcagatgc aagcttttga
     4861 acaccgttta agaaagaggt cgtgagcctg ccgtttcact ctgagtcaca aagagcaatt
     4921 tcaaaaaata gcttctcatg tttgttgaat attgtgtctt gtgaccgagg agttgtcagg
     4981 agaacaccgt ttaccagagg ttgtgacttg tttttagtca cgacctcttt ttttatttat
     5041 tccatataaa tacacattat ttattccgaa aagtgaaagc gcaaataaca aaaacaacca
     5101 acttatttat tattaaagaa aagcgtattt aagtaggacg attctgttga gagctttcgt
     5161 agattttccc attttcctat ggtaaactga caaagttgag aatgttagaa cagatcgttt
     5221 aggaggaaac agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa
     5281 aaaaatgcaa cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat
     5341 gggacgctta taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat
     5401 cgagcatttg ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt
     5461 tacagtaaag atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt
     5521 gatatggtac agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac
     5581 tttgcggtta caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa
     5641 gcgaagtctt tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat
     5701 tatacacaag caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa
     5761 aagaaggaag gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa
     5821 tcgaagaacc agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta
     5881 aaggtcgtat tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa
     5941 acacgactgc ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca
     6001 agatcgatcc aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc
     6061 ttgtaagttt aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt
     6121 caccgcaaga atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga
     6181 atgattatga atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt
     6241 ttcgagagct tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag
     6301 tgacctactg tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag
     6361 gattcaaaga tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag
     6421 tccaaggaga attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata
     6481 tcaaccaagt agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac
     6541 gatatatcaa ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg
     6601 aagaaaaaca tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg
     6661 ttcaagacca tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat
     6721 agaaaacaat agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat
     6781 ggtgatccac atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct
     6841 ttttgaaaaa cttattcact attatgatcc aaagatccat cagcttgttt tattagggga
     6901 tctcaatgat cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga
     6961 agaaacagga gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca
     7021 atcaccggag gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag
     7081 cctgattcac ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca
     7141 atcgagatat tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga
     7201 aaattatctt tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag
     7261 tctaagagac tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa
     7321 gacaattgta tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga
     7381 cctctggatt caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt
     7441 gcatggggtt gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga
     7501 aggaccttgg catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg
     7561 ctctttttat ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt
     7621 atgatagaat aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg
     7681 aaccagacga tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg
     7741 actactgtac ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga
     7801 aaagaaatga ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc
     7861 tatcttgaaa acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg
     7921 aaactgactc ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa
     7981 gatttgtatc gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa
     8041 ggacttgaac cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa
     8101 gcagaaaaat atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt
     8161 gctcatgaga ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg
     8221 tcttatacgt ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa
     8281 aaaggcgtat atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat
     8341 cgaatattag ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta
     8401 gatgaagcag caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct
     8461 tcttcttcat tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca
     8521 atcgagcgag aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt
     8581 ttcggcgaaa acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg
     8641 ggatttgatc cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa
     8701 gttttagcaa tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct
     8761 gctggaccag cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga
     8821 aatggtacag ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac
     8881 cataaaacct attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa
     8941 attgcacgaa aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc
     9001 cgtcgcctgc aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta
     9061 ggccagtacc aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg
     9121 gaaacagcgg ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag
     9181 catatatcag gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac
     9241 ggagaattca ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat
     9301 gaacaagcaa tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt
     9361 atccatcccg aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa
     9421 aaagagcttg gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg
     9481 gctgaaagcc tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa
     9541 cctggacgag atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt
     9601 atggaagact tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc
     9661 ggcgcatttg ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc
     9721 aaaaaattcg tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg
     9781 atagaacaag tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa
     9841 gagtaacaat gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga
     9901 gatatcatta aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt
     9961 acgtacaact ggcgggcgct atcatttaaa cgatcatcat tta
//
LOCUS       DADVXB010000100         9934 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.102, whole genome shotgun sequence.
ACCESSION   DADVXB010000100 DADVXB010000000
VERSION     DADVXB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.102"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            573..1727
                     /locus_tag="KB902_002007"
     CDS             573..1727
                     /locus_tag="KB902_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6808800.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1721..2143
                     /locus_tag="KB902_002008"
     CDS             1721..2143
                     /locus_tag="KB902_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808801.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2445..2825
                     /locus_tag="KB902_002009"
     CDS             2445..2825
                     /locus_tag="KB902_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6808802.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            2807..3721
                     /locus_tag="KB902_002010"
     CDS             2807..3721
                     /locus_tag="KB902_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6808803.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3961..4650
                     /locus_tag="KB902_002011"
     CDS             3961..4650
                     /locus_tag="KB902_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808804.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTA
                     CYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(4770..4856)
                     /locus_tag="KB902_002012"
     CDS             complement(4770..4856)
                     /locus_tag="KB902_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6808805.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            5502..6434
                     /locus_tag="KB902_002013"
     CDS             5502..6434
                     /locus_tag="KB902_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6808806.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            6451..6921
                     /locus_tag="KB902_002014"
     CDS             6451..6921
                     /locus_tag="KB902_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6808807.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            7005..7309
                     /locus_tag="KB902_002015"
                     /pseudo
     CDS             7005..7309
                     /locus_tag="KB902_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7584..8765
                     /locus_tag="KB902_002016"
     CDS             7584..8765
                     /locus_tag="KB902_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6808808.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
     gene            8855..9124
                     /locus_tag="KB902_002017"
     CDS             8855..9124
                     /locus_tag="KB902_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HBB6808809.1"
                     /translation="MKKTKLLVASLCLFSSLLAFTPSVSFSQNGGVVEAAAQRGYIYK
                     KYPKGAKVPNKVKMLVNIRGKQTMRTCYLMSWNASSRTAKYYYYI"
BASE COUNT         3688 a         1575 c         1638 g         3033 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattaa attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaacaaacg gataaataat aaaaaagact
      181 gctctttcga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcacgcgctt
      241 atgaagcgct accaaaaatt taccatattt tacaaaaaat aacaagtctt aaaaaaatga
      301 cagataaaaa tgcacaaaga attagatata gataaccgcg aaaaatcaag ctttagaaag
      361 ttgcttttag ctagaccaat taaaaatcac aaagtgagcg tctctatcca ttggtagagg
      421 ggctacttgg catagtcgac attatgttaa ctaacgctat aaataacgat tatgttccca
      481 aaacaatatt ttatgaacta taacaaaaat ttgttatcgc atattgtata ttttaattat
      541 aggtgtatac cacttaaatt taacacaaag gcgtgattat tttgaaaccc aaaaagaaaa
      601 tttatctagg tctcctcttt tccttgatga ttggaatttt tagtatagga attacaaata
      661 cctatgcttc agaaaattct aatttcaata tcaactccca accaattgaa gaacaagcaa
      721 ttaattttgc gaaaactgat tttgaacact ccataacttc aattctttta atggaaaata
      781 acaccgaaac tgatattaac tatactcttg gttcgccatt taaaatgctc gatggagaaa
      841 atacggcaaa tagttctatt ttctttccag tattttcaga cgctgataat acgattaaat
      901 atatttatac cgtcaaaaaa aatacaaatg gagaatattc aggaagtatt tcacaatttt
      961 tagcaaaaga acttcaaaat ctagtagata gtaatataac agatacaacc ttattttttc
     1021 aagataatag catttattat tccgataatg gacaaattaa actactttgg aaatcacctt
     1081 taagtacaga aaaaaatggt gtttcttcct ttacagaaaa aaatgatctt atatccgtaa
     1141 atataaaaaa taaaattaaa aatttctcta aaaaacaaaa ttttcctgcg attaaacgtg
     1201 taaaaagtgt ctcctccgga gataacttta ttatgattaa ttggcgtata gcagaaaccc
     1261 aaacaagttt tccgtggtgt gctgcttacg tagaagctgc tatcttatgt aacaaaacag
     1321 atgtacatgc tacttcagct agagccatta tgcattatac ctatcctaat ttaaacaaca
     1381 gtcaaattga atcaaaaagt cttaatcaag atcaaataat aaaatatgca aattactgtg
     1441 gtgtttatcc taaaaaagta gcacgaatac taaacctttc agaggtccaa acacaactaa
     1501 gaaaaggaaa tgccatttat atgggaactg ctggttatgg aaattatagt aacagccgtc
     1561 atgcacttgc attatttggg tgggtcaatc aaggtggtta tcaaacttac tatgtgtgga
     1621 atccttggta taactaccca actgtaataa gtgcaaatgc aggaccagtt acaattcctg
     1681 tacctggagg tggttttact tgggacaata ccattacaaa ttggtaaata aacccattgc
     1741 tttagttatg ggtctagtgt tagttctttt cttaactagt tgttcaaaaa aacaagaaat
     1801 acaaaagact gatctgattc cttttctagg aacttggcaa actaaagatc attcagaacg
     1861 tctagtaatc actaatttaa atacttcaaa aaatatagaa caatatacca tcttagtaaa
     1921 agagaacaat cataaaattc aaatcattga taaaaattta aatataaatg aacaagtttt
     1981 catttacaaa gcaacaaata atttactaac actgcgctct aataaaaaac aattagatta
     2041 cacttttagt ttggattctc caaaaaagct cgtatttatt ttgacaacga atgatgggac
     2101 agaagggaca gctaaaccaa ttgaattttt taaagctgat tgatgaatag ttgtttgata
     2161 ttacaaaaca ataatttcac cgaaggtgaa acaagcgaaa ctttacaaaa agtggctagc
     2221 atttgctagc cttttttgta ttgtggagcg tgggttttga gggggattca agggggagct
     2281 tgcgcccctt tgaaaagcgg ttatttgcac caaatacgta ggtatttggc tagcaaatat
     2341 agagcttgcc aaaccctttt agtgagcttt actcattgta cctttttagg tacaatggta
     2401 ttgcgaacga tacgtccgta ggacgtactg aaagggtggg acttatgagc gaacaaaatc
     2461 aaaatttggc tagcgatcat tctaaaaaat atacctatcg atccgagcca aaacaaatca
     2521 gttttcgagt gagcgaatct gaatttgcaa agctgaagca gtcagctgaa gctttgcaaa
     2581 tgagtgtgcc ggctttcgta aaagccaagg cacaaaacgc gcgtctggtg acaccgaaag
     2641 tggcgccaga cattgcccag gcaatcgcgc gcgatttagc caaagctgga gggaatatca
     2701 atcaaattgc taagtggtgt aatacacacc aacacgacgt tgctcctgga gacgcccaac
     2761 gcttatccga aaacctaaaa atcatgcaaa aggagctaca aaagatatgg caacagttaa
     2821 agtaagccga accacttctt gtagtcgtgc aattaattac gctgaaccac gagcaaccat
     2881 taaaacagga ataaactgtg acgtcgatta tgccaaaagt gaaatgaaac aaattcgcat
     2941 gctgtatgga aaagacgacc gtgtacaggc acacttattg attcaatctt ttcgaccagg
     3001 agaaattacc gctgaaaaag ctaatcaact aggggcagag tatgcaaaaa aaatagcccc
     3061 cgatcaccaa atagctattt acacacatac agacaaagac catattcata atcacattgt
     3121 cattaactcc gttaatctgg agactggaaa aaaatttcaa gctcatggtc aagcatttct
     3181 aaacaaatgt tatgacctaa atgacgagat ttgtcttgca cataacttac caatcactga
     3241 gcgaggaaag aaaccagaaa aacgaaccat gtctgaaata aaattaaaag aaaaaaatga
     3301 acctgtttgg aaagacgaaa ttcggattgc gatcgatcaa acaatgaaaa acaaaaaaac
     3361 cagaacctat gaccaatttt gtaattccct caaaacattg gggattcatt gcttcaatcg
     3421 cgggaaaaat ttcacttacg aattgatcca caaaaagaaa aaagtacgat ccaacagact
     3481 aggaaaggac tacgaaaagg agacgatttt acatgagctg gacagacgag aacgaaccta
     3541 taaccaacag cgaaccaacg agctacgaag agctcgagct agcattcgcg aaactgcaga
     3601 agaagtacga agagaacaac gaactcttac gcctgaacaa ccggaaatta gaccggctcg
     3661 aagaaaccat gaacaacacg ttgaaagagg aacagaccac caacaagaat tatcgctcta
     3721 aaacgttaaa agacatagaa aacgaaataa agaaacaacg tgcttttctc gttccttata
     3781 cgcaagaaag gatacaaact acgattgatt tacaagttaa aaaactccat caagagctat
     3841 tagaccagcg aaataaggaa cagaaaaagg tgcttattca acgatcattg gattttcttg
     3901 cccccttatg ttgcttagtc ctgacactgt tcgcattttg gttagtatgg ggaggctaaa
     3961 atggcatttt atttacccta tctactcatt tttgttagta tttcaggaag tatttggctc
     4021 atctataaaa tttttcaaac aagatattca ttaaaaggct ctaaaattcg atttaagcga
     4081 tttttctttc ttggctgtat attttccttg ataatcgttt caagcggctt attcggcgtt
     4141 ttagagggaa ataagcgcgt ttctagaagt attttattag gaaatgtcac tcaaaagtat
     4201 gaatcagcgc gtgataaaaa gaaaaaagag caagtattag cacaaaaaat agaaaaattt
     4261 accgcttgtt atgaggacat gaatgatatt tttgtgaagc aagaaaagcg tttgacggat
     4321 aaaaatatgg aaacactcac tcgactttat cggaatttgc cagaagaaca gcaaaaagag
     4381 taccaagaaa aatatgaaca agtaaaaaaa gacgtgcaat atgtgaaaga tacgaaagtg
     4441 gaagaagctt gtagtgattt atttggagat acaattcctt tttcaactag cgaacaagaa
     4501 cgaaaagaac gacaacaatc agtcacatat gaacgctatg aaatcttgct tcaacaagca
     4561 attaacatac aaaatctgac taaaaaagaa acagctttaa attatttaaa aagcgtcaag
     4621 gaatggttag atcagcaaca gcaaaattga atttgattga aattcatgtt aaactaaaca
     4681 tgcaaatgtt caaacattag atacacgaaa gccccagaga ggtcggattc tctggggctt
     4741 tttttaggtt gatgtcgcct ttactgattt tacttcttgt ttcggttatt caaccaataa
     4801 ctgaatacag agatacaaac tcctacaaga agggggcaaa taaacagttc aaacatcaga
     4861 tacacctcct tccagtcgca agactgtcgg ataggcgaca agttattata ccctacaaaa
     4921 ttaaatctgt gtggcaattt taagtatctc ttatttccgg gttgttaggg cttgccctga
     4981 ccgcctgtag ggcgctttaa atgccagata aaggttttta tactaagact gtcttaaaac
     5041 ggcttagaca agctcttaga gcctcaaccc tcctttttga acaatggttt tagcaaagga
     5101 gctggaggcg actgcgcagg tataatgtga gagcgtagcg atcacacctt tttggcgacc
     5161 gtagggagcg aggttttgaa ttagcagttt agaaaagttc gcgaacctgt ttaaagaaaa
     5221 aataattgtt tttttaggtg ggaaattttg tctccctctt ttataatctt tttttaaacc
     5281 tctttttaaa cctctttacc gtcggctgtg tccttactcc cccaagggat acaaaatttt
     5341 ataggcatga aattatctgt ttataggcat gaaattatct gtttataggc atgaaattat
     5401 ctgtttatag gcatgaaatt atctgtttta ggtattgttt ttagacataa tatgtcctaa
     5461 aatgatgtca ataaaatcat ttagactgga gtaacaacta aatggcaaat gaaatcgtaa
     5521 agtatgaacc agaattaaat accattcctt taagaaaatt taccccaata gaaatgaact
     5581 tgtttttttc tattgtctct agaatgcgcg ataaaggtaa tcaaaaaata cgcttttatt
     5641 tcagccaact taaagattta agtgcgtata agcagactgc aggagaagtc tttataaaag
     5701 atttggcaag aacatacgat catttgatgg atttacgttt cggaagaaaa agcaatggtg
     5761 gattaacaat agaacgattt acaatgttta ctgattttga aattcatgga gaagtcgata
     5821 acccttatgt agatataaaa gtccacgaaa aagctttgcc tttacttaat aatctagaaa
     5881 gctgggtacg tttctcttta acagaatttc gagatttaaa tagcagttat gctaaaacaa
     5941 tgtttagatt gctaaaacaa taccgaactc aaggatgggc tgaattttct aaggaagatt
     6001 ttttagagct attagatatt cctaaaagct atagacaaac aaatataaat cagtttgtac
     6061 tcaaaccaat aaaagaagaa ctaactccac tatttaaagg attaactatt cgtaaaaaat
     6121 atggtaaagg tcgaggtaaa cctgttattg gttatcgttt tacttggaaa gctgaaatca
     6181 accatgctga cgatttttca aaagggaagc aagaagattt acgtataaaa ttatttaata
     6241 ttgaacacaa tggagaatta acacaaaaag aaaaatggcg tgctaaagat cgaatactaa
     6301 atcttccgtt aggtactcat gaagctgatt ttaaaaaaca acaacaaacc gaaaaagaag
     6361 aagcggaaaa acaatcaatc tcaaatgagc ttaaacaaga tttattagaa aacttacaaa
     6421 acttattcga ttgaagcata aggagtattt atgatagata aaacgatcaa agaactcgcg
     6481 gaagaatttc atgtttcaaa acaagcaatt aggaaaaggc tatcagctga ttttagagaa
     6541 aactatgtgc aaactgttac taggaacgga gtgaaaacct tagttgtcag ctacaaagga
     6601 tatttgcttt taaaacaaca ttttttaggt agtaacacca ctggtaacca agtagaaacc
     6661 gttgctagta acgatgaaaa ctcgattatt gtttttttac atgaacagct ccaagaaaaa
     6721 gatactcaaa taaaacaaat gcaaaagtta ctcgaccagc aacaacaact caccttgcag
     6781 gcaaatcaac agatcgaaaa actgcaagaa cagttacaat tagcttatac ggaagaacct
     6841 gaagaagagg aattaacttc tgtcaataaa gaaaacaaca atgcaataac aacagaaaaa
     6901 aagtggtgga aattttggta acaattacca actttccata aagaagaaat caatttctat
     6961 agactctatc tttctaagaa taaaaaatat gtttaggtga tcaaatgact ataagtaaag
     7021 taatcaaaca aaaaagaata gaaaaacaac taactcaaga agatttagct gaaatgcttt
     7081 tagtatctaa aaaaaccatt tctaattggg aaaatggtcg aacaatacca gatacagaaa
     7141 atttaattca gtttgctaag ttatttgatt tatcactaga caatattttg ttaggagaag
     7201 aaaaaattat ggtaaaaaat catacaaaaa cactaatact attatttcat tttgtaattt
     7261 ttttaagttt agttttcacc ttaattcagt ccggattctt ttattttagc cattcaattg
     7321 ccacttggtt attaatattt tttctaagtt tactattaat aattaatact ttaattatta
     7381 tctttaataa acatagaaac ttatttcttc acagcatatt tccaattgtt ttattaattt
     7441 ttctatactt tatataaaaa gatagaacta tttagtaaga taaaaaagta gctaattgta
     7501 attttcgtct aaaactcaaa actagtaaaa ataactttat tgtgttattt ttatttataa
     7561 attatgaaaa aggacctttc gaaatgaaaa ataatagaat ctacaaaaat cagttgaatt
     7621 atgggctttt attgccagtt tttctgctat gtatcattgg attactttct ttatatgttg
     7681 ctttatatca cgactcttac actaattcaa aaatcacaaa agaattaatt aaacaagtat
     7741 tgtggtatag tattgggttc acttcagcaa taactattta tttttttaat cctaaaattt
     7801 tgtggaaatt aactcctata ttttacggat tatgcatcat aatgttatta cttctcttga
     7861 aattctataa tccacaatta gcagtcttaa ctggagcaaa aaattggttt tatattgctg
     7921 gtttttcgtt tcaacctact gagttagtca aaataggata cacccttatg ctagctaaaa
     7981 taaccgtcaa ttatcagcaa aaatctatta ctagtaatac gaaagatgat tggatttatt
     8041 tacttaaaac ttttattgct actcttccaa taggaatatt attatttttt cagaacgatc
     8101 taggaacaat gttagtcttc attgttattt atatttttat tttgtttacg tctaacataa
     8161 atataaaaat aattgcccca ataatcgcca ttggtgttgt tttatcctta atatttttat
     8221 atttggttat atcagataca ggaagagatt tcttattaaa aataggattt cacgactatc
     8281 agtttaaaag aatagactca tggttgaatc catttttaga tccaaatgga tctagctatc
     8341 agttagcaaa tagtttaatt gctattggct ctggcggact tttaggtact ggttttaatg
     8401 tatcaaacat tcacgttcct gttagagaat ccgatatgat attttctgta attggagaaa
     8461 attttggctt tataggaagt tgtcttgtaa tattcctata cttttattta atttatcaaa
     8521 tgtataaaac atgttttaaa agcaataact tatttttcac ctatatcggt ataggcattg
     8581 ttgcaatgat tttttttcat gtttttgaaa atataggtgc aagtatcgga ttactacctc
     8641 taactggtat tccactcccc tatattagtc aaggtggttc tgccattctt agtaattttt
     8701 tggggttggg atttatgttg tgttgtagta gatatactaa cgaaaaaaaa ggaacacaaa
     8761 aatgaattca aaataacact ttatgaatag aatgtctatt tcaataaaaa ttatgatacc
     8821 ttaaagttaa tcattaaaaa aggagtgtca taatttgaaa aaaacaaaat tattggtagc
     8881 tagtttgtgt ttgtttagca gtttattagc tttcacccct tctgtttcat tttctcaaaa
     8941 tggtggagtg gttgaagctg ctgctcaaag aggatatatc tacaaaaaat atccaaaagg
     9001 tgctaaagtg ccaaataaag ttaaaatgtt agtaaatatt agaggtaaac aaactatgcg
     9061 tacttgttac cttatgagtt ggaatgctag tagtagaaca gccaaatatt attactacat
     9121 ttagtaaaaa caaaacattc tttctataca ataaaatagc gtatagagag gatgttttta
     9181 atttgaaaag gagtggttat ctttatgaaa aatagatcat ttgctatatt agtattatcc
     9241 gtaattttat tagatatatt gttaataaca ttagctttaa aaactttaaa tttagtaaca
     9301 agttttgtca ttataccagt aattatagga atgtctattt atttcatcaa aaaaaataaa
     9361 caattttttt gaatgaaatt acgggcgaaa ataatcactc aaaattatta ataaaaacga
     9421 atcaactact ttttctgaag aaacatacaa ccgtaaacaa caattgttgt ttacggttgt
     9481 aaattatcaa actatatggt gacttgttgc ttaaaatagg ttgaaatttc gtttattttt
     9541 tttgagaaat tttacccacg tactacccat gtacctatcc acgtattacc catgtacccc
     9601 cccatgacaa atgggcggag gggcttgcgg cgcttggtat taaaggcatt atccgcctcc
     9661 caggtttctg accattttct ctcataagtg gggtttttac cgcgttgaga gaaaatggtc
     9721 agaaacctaa acgatcggca aagaaaacat accaagcgcc acaagcaaaa aaagttagag
     9781 taacttccag aaaagaaaaa tttttagaac aacttttgaa aatttgattt tgatttatat
     9841 ccgttcaatt taaacatttg ataaactgaa ggctagtatt taaaatgtgt atacaagtgg
     9901 tagcgttaaa aaaagtggag gtataaccta tgtt
//
LOCUS       DADVXB010000101         9826 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.103, whole genome shotgun sequence.
ACCESSION   DADVXB010000101 DADVXB010000000
VERSION     DADVXB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.103"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..658)
                     /locus_tag="KB902_002018"
     CDS             complement(<1..658)
                     /locus_tag="KB902_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6808810.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     K"
     gene            complement(663..1430)
                     /locus_tag="KB902_002019"
     CDS             complement(663..1430)
                     /locus_tag="KB902_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6808811.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1919..2344
                     /gene="lacA"
                     /locus_tag="KB902_002020"
     CDS             1919..2344
                     /gene="lacA"
                     /locus_tag="KB902_002020"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBB6808812.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2361..2876
                     /gene="lacB"
                     /locus_tag="KB902_002021"
     CDS             2361..2876
                     /gene="lacB"
                     /locus_tag="KB902_002021"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBB6808813.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2887..3819
                     /gene="lacC"
                     /locus_tag="KB902_002022"
     CDS             2887..3819
                     /gene="lacC"
                     /locus_tag="KB902_002022"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBB6808814.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3822..4802
                     /gene="lacD"
                     /locus_tag="KB902_002023"
     CDS             3822..4802
                     /gene="lacD"
                     /locus_tag="KB902_002023"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6808815.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPAIKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4830..5147
                     /locus_tag="KB902_002024"
     CDS             4830..5147
                     /locus_tag="KB902_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6808816.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5147..6853
                     /locus_tag="KB902_002025"
     CDS             5147..6853
                     /locus_tag="KB902_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6808817.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7000..8406
                     /gene="lacG"
                     /locus_tag="KB902_002026"
     CDS             7000..8406
                     /gene="lacG"
                     /locus_tag="KB902_002026"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBB6808818.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8529..8702
                     /locus_tag="KB902_002027"
     CDS             8529..8702
                     /locus_tag="KB902_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HBB6808819.1"
                     /translation="MKLPPLLKCGKWYVLTGKEWICHSDLELSAFEWEFLQSLDVEIR
                     ETIHFEVNYLPFQ"
     gene            8723..9622
                     /locus_tag="KB902_002028"
     CDS             8723..9622
                     /locus_tag="KB902_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6808820.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNCPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDKL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3094 a         1666 c         1976 g         3090 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagcagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttt cgtgtattta ggaaaagcaa catcagacca acatctgaaa cgtttgtaaa
      541 tgttatctat ttgttggata tcaatcgttg gaaaacattt ctcaacgcta cgtttaaagg
      601 ggagttgatg gtcataaaga gtgtcatcaa ggtcaaaaac aatattttta taagtcataa
      661 ttctagtccg cttttaaaat agtagtgtac tggctaaatt cctctaagtg ttgagggcta
      721 atctggttat ctgtaatgat ggtatcgagt tgatctagat tatagaagtt aaagaaatcg
      781 tatcgatcga atttagtact gtctactaat aagaattttt ctacagcatt gtttagggca
      841 agttgttgaa tcacaccttc cttgtcacta tatgtagcaa tagaattatg ggtaacagca
      901 tttgcactaa caaaagcttt ggcaaatcta attgctttta aatttgtcga agccattgaa
      961 cctacaaaag ctccagttat ttctctatat tcaccgccaa gaagcaataa atcaatggtt
     1021 tcgctatcat ttagaatcaa gaacacaggg agactatttg taatgacacg aattttataa
     1081 cctttacgac ctttcaattc taatgccagt tgttcaagtg tagttccggg tccaataaaa
     1141 atagtatcgc catctttgat taaagagcag gcttttttag caatgtcaat tttttctttt
     1201 gtatttagac ttttcttctc gatatgtgtc ttttcaagtg gctttttaga ggaaagcaat
     1261 tgtgcaccac catgagtacg tgttaaaagt ccatcagctt ctagagcatc aaggtctcta
     1321 cgggctgtca tatcggaaat atctagttca tctattattt cttttatggt tatggtccca
     1381 tcaatcttta acatatctaa aattttttct aatcgtcgtt ttttgttcat atgaagaccc
     1441 ttctttcata aagtaatttt tttccaaaga taattctctt ttaattgtat cataaaagac
     1501 aatattttca aggtaaaaca aacaatttca aacaaaaaca aatgttagat gatgaaataa
     1561 gaacagtgga ttgacgtata ttagcttagg tcagattttg tataagacga aaataaagta
     1621 ggacctctta atcagtaagt tatagaaagt aaaagacttt tgtaatactt gaatagatat
     1681 ttcacgtcca ttttgtgatg gattaaatga acaaaaatga acaataattt aacggtgtta
     1741 tctatttttt aaaaaaacaa ataaaaaaac aaaaaataaa caaaaaaagt gttgcttttt
     1801 gtttgaatgc ttgatattat ataaacaaag aaatgatgaa aacgtttttt cgaacatttt
     1861 gcaaaatgtt ttctacttct acgtagcatt tctttctaaa atttaggagg tggtcaaaat
     1921 ggctattgtt gttggtgcag atctcaaagg tacgagatta aaagatgttg tgaaaaattt
     1981 tcttgtagaa gaaggttttg aggtaattga tgtgactaag gacggacaag attttgttga
     2041 tgttaccttg gcagttgcct ctgaagtaaa taaagatgag caaaacttag gtattgtaat
     2101 tgatgcttat ggagctggtc cattcatggt agcaactaaa attaaaggta tggttgcagc
     2161 agaagtttca gatgaacgct cagcttatat gacacgtgga cataacaatt cacgaatgat
     2221 tacggttggc gctgaaatcg tcggtgatga gcttgctaaa aacatcgcta aaggtttcgt
     2281 caatggtaaa tatgatggcg gacgtcatca aatccgagta gatatgctta acaaaatgtg
     2341 ttaagaaaag gagttaagga atgagaatcg caattggatg tgaccacatt gtcacagatg
     2401 aaaaaatggc agtatcagaa ttcttgaaat caaaaggaca tgaggtcctt gatttcggga
     2461 catatgacca cgcacgtact cactacccta tctatggtaa aaaagtcggt gaagcagtag
     2521 taagtggtca agcagacttg ggagtatgta tctgtggtac aggtgtcggc attaacaatg
     2581 cagtcaataa agttccaggt gttcgctcag cgttggttcg tgatatgaca tcagctatat
     2641 atgcaaaaga agagttaaat gcgaatgtta tcggtttcgg tggaaagatt actggtggtc
     2701 ttcttatgaa tgacatcatt gaagctttca ttgaagctga gtacaaacca acagaagaaa
     2761 ataaaaaatt gattgcaaaa atcgaacacg ttgaaacaca taatgcacat caagcagatg
     2821 aagatttctt tacagaattc cttgaaagat gggaccgtgg tgactaccac gattaaggta
     2881 taacaaatga ttctgacagt cacactaaat ccttcagtag acatctctta tcctctagaa
     2941 acattgaaaa ttgatacagt gaatagggtg aaagatgtta gtaagacagc tggtggaaaa
     3001 ggcttaaatg ttactagagt cttgtatgaa tctggtgata aagttactgc tacaggtttc
     3061 ttaggtggta aaattggtga atttattgaa agcgaattag aacaatctcc tgttagtcca
     3121 gctttttata aaatctcagg aaacactaga aactgtattg ctatcttaca cgagggtaac
     3181 caaacagaaa ttttggaaca aggaccaaca atttctcatg aagaagcaga aggctttctt
     3241 gaccactata gcaatcttat taaacaatca gaagttgtga caatttcagg aagtttacct
     3301 tcaggacttc ccaacgatta ttatgaaaaa cttatccaac ttgcttcgga tgaaggagta
     3361 gcagtcgttt tggattgttc aggtgcacct cttgaaacag ttctaaaatc gtcggctaaa
     3421 cctactgcca tcaaacctaa taatgaggaa ctttcacagt tgcttggaaa agaagtaaca
     3481 aaagatattg aagaactcaa agacgttctt aaagagtcac tttttagtgg tatcgaatgg
     3541 atagtggtct cattaggtcg aaacggtgcc tttgcaaaac atggtgatgt tttctataag
     3601 gtagatattc ctgatatccc agttgttaat ccagtcggat caggggactc aacggtagct
     3661 ggtattgcat cagctttaaa tagtaaaaaa agtgacgctg acttattaaa acatgcgatg
     3721 acattgggta tgttaaatgc tcaagaaaca atgacagggc atgtgaatat gactaattac
     3781 gaaacactaa actcacaaat tggagtaaaa gaggtataaa aatggtactt acagaacaga
     3841 aacgcaaatc tttggaaaaa atttcagata aaaacggtgt tatctcagct ttggcatttg
     3901 accaacgtgg tgctttgaaa cgtttgatgg cacagtatca agatacagaa ccaactgtag
     3961 ctcaaatgga agaactaaag gttttggttg ctgatgaact tacaaaatac gcttcttcaa
     4021 tgttgcttga ccctgaatat ggacttccag caataaaagc attggataaa gaagcaggtc
     4081 ttcttcttgc ctatgaaaaa acaggttatg atacatcaag tacaaaacgt ttgcctgact
     4141 gcttggatgt ttggtctgca aaacgtatca aagagcaagg cgctgatgcc gttaagttct
     4201 tgctttacta tgatgtagac agctcagatg aacttaacca acaaaaacaa gcttatattg
     4261 aacgtgttgg ttctgaatgt gtcgctgaag atattccttt cttcttggaa atccttgctt
     4321 atgatgaaga aatctcagat gcaggttctg ttgaatatgc aaaagtgaaa cctcgcaaag
     4381 tcattgaagc gatgaaagtt ttctctgatc cacgctttaa cattgatgtt cttaaagtag
     4441 aagtaccagt taacgttaaa tatgtcgaag gttttgctga tggtgaagtg gtttacagta
     4501 aagctgaagc tgctgacttc tttaaagcac aagaagaagc gactaacctt ccatacatct
     4561 acctaagtgc aggtgtatct gctaaattgt tccaagaaac attgcaattt gctcacgact
     4621 caggtgccaa gtttaatggt gtgctttgtg gacgtgctac ttgggcagga tctgtagaac
     4681 cttacatcaa agaaggtgaa aaagcagcac gtgaatggtt gcgtactact ggattcgaaa
     4741 atattgatga acttaacaaa gttcttgtta aaacagctag tccatggact gataaagtat
     4801 agtaaaaaca taaaacggag gatattgtta tgaacagaga agagatgact ctcttagggt
     4861 ttgaaattgt tgcttatgct ggagatgctc gctctaaact tttagaagcg cttaaagcgg
     4921 ctgaaaatgg tgatttcgct aaggcagata gtcttgtagt agaagcagga agctgtattg
     4981 cagaggctca caattctcag acagctatgt tggctcgaga agcttctggg gaggaacttc
     5041 catacagcgt taccatgatg catggtcagg accacttaat gactactgtc ttattaaaag
     5101 atgtgattca tcacctcatc gaactttata aaagaggagc aaaataatgc ataaactcat
     5161 tgaacttatt gagaaaggga aaccgttctt tgagaaaatc tctcgaaaca tctatcttcg
     5221 tgctattcgt gatggattta tcgctggtat gccagtcatc cttttctcat ctatctttat
     5281 ccttattgcc tatgtcccaa atgcttgggg attccactgg tcaaaagaca ttgagacctt
     5341 cttgatgact ccttatagct attcgatggg tatcctagca ttctttgttg gtggtactac
     5401 cgctaaagct ttgacggact caatgaaccg tgacctacct gcgaccaatc agattaactt
     5461 cttatctacg atgctagcgt ctatggtagg gttccttttg atggcagctg agcctgcaaa
     5521 agaaggaggc ttcttgacag ccttcacggg aacaaaaggt cttttgacag catttattgc
     5581 agcctttgtg acagttaatg tttacaaggt ctgtgtgaaa aataatgtta ctattcgtat
     5641 gcctgaagag gttccaccaa atatctctca agtatttaaa gacttgattc cattcactgt
     5701 agcggttgtt ctcctttatg gatttgaact cattgttaag ggaactcttg gtgtaaccgt
     5761 tgcagaatca atcggtaccc ttcttgctcc tctcttctca gctgcagatg gttaccttgg
     5821 aattacactg atctttggtg cttatgcctt cttctggttt gttggtatcc acggtccttc
     5881 aattgtcgaa ccagcaatcg ctgctatcac ttatgccaat atcgatgcca acttgcatct
     5941 tatccaagct ggacaacatg cagataaagt tatcacttct ggtactcaaa tgtttattgt
     6001 taccatgggt ggaacaggag ctacattgat tgttccattc ttgttcatgt ggatttgtaa
     6061 atcagaacgt aaccgtgcca tcggacgtgc ctcagttgtt ccaacattct ttggggttaa
     6121 tgagccaatc ttatttggtg caccaatcgt attgaatccg attttctttg taccgttcat
     6181 tttcgctccg attgtcaacg tttggatctt taaattcttt gttgacacat tgaacatgaa
     6241 ctcattctct gccaaccttc catgggttac tcctggtccg ttgggaattg tactcggtac
     6301 taacttccaa gttctatcat ttatcttagc cggactcttg gtagttgttg atactatcat
     6361 ttattaccca tttgttaagg tatacgatga acaaattctt gaagaagaac gttctggtaa
     6421 aacaaacgat gctcttaaag aaaaagtagc tgcaaacttc aatactgcta aagcagatgc
     6481 cgttcttgga aaagcaggcg ttgctaaaga agatgtagca gcaaacaata atatcacaaa
     6541 agaaactaat gtccttgttc tttgtgcagg tggaggtaca agtggcttgc ttgccaatgc
     6601 cttgaacaaa gcagcagcag aatacaatgt tccagtcaaa gcggcagcgg gtagttatgg
     6661 tgctcaccgt gaaatgttgc cagagtttga cttggttatc ttggctccac aggtcgcttc
     6721 aaacttcgat gatatgaagg ctgaaacaga taaattgggc attaaacttg caaaaactga
     6781 aggagctcaa tatatcaaat tgacacgtga tggacaaggt gctcttgcat ttgttcaaca
     6841 acagtttgat taataaattt gtaaaagtta tttgagacga gattattctt tcagttcctt
     6901 ataatattgt taaccatatc attgcatttc atttcatttc cttggtttcc ggaactcaga
     6961 atatcgtctc aaatgctttt tttgaaagga tttatagtta tgactaaaac actccctaaa
     7021 gattttattt ttggtggtgc tacagctgct tatcaagcag aaggtgcgac tcacacggat
     7081 ggtaaaggcc cagttgcatg ggataagtat cttgaagaca attattggta cacagcagag
     7141 cctgcaagtg atttttacca taaatatcct gttgatttag aattagctga aaaatatggc
     7201 gttaatggta ttcgtatttc aattgcctgg tctcgtattt tcccaactgg ctatggcgaa
     7261 gtaaatgaaa aaggtgttga attctaccat aatctttttg ccgagtgcca caaacgtcat
     7321 gttgagccat tcgtgacttt gcaccacttt gacacaccag aagttcttca ctcagatgga
     7381 gatttcttaa accgcgaaaa tatagaacac tttgtagatt atgccgcttt ctgttttgaa
     7441 gagttcccag aagtaaacta ctggacaact ttcaatgaaa ttggcccaat tggagatggt
     7501 caatacttgg ttggtaaatt ccctccaggc attcaatatg atcttgccaa agtcttccaa
     7561 tcacaccaca atatgatggt ttctcatgca cgtgctgtga aattgtataa agataaaggt
     7621 tataaaggcg aaattggtgt agtacatgcg ttgccaacca aataccctta tgatccagaa
     7681 aatccagcag atgttcgtgc cgctgagtta gaagatatca tccataacaa atttatcttg
     7741 gatgcaacct accttggaca ctattcagat aaaacgatgg aaggggtcaa ccacatccta
     7801 gctgaaaatg gtggagaact tgatcttcgt gatgaagact tccaagcact tgaagcagct
     7861 aaagatttga acgatttcct tggtatcaac tactacatga gtgattggat gcaagccttt
     7921 gatggtgaga ctgaaatcat tcacaatggt aagggtgaaa aaggaagttc taagtaccag
     7981 attaaaggtg ttggtcgccg aatcgcacca gattatgtgc ctagaacgga ttgggactgg
     8041 attatttatc ctgaaggctt gtatgaccaa atcatgcgag tgaaaaatga ttatccaaac
     8101 tacaagaaga tttacatcac tgaaaacggt cttggataca aagatgagtt tgtagataat
     8161 accgtttatg atgatggtcg tattgattac gtgaagaaac acttggaagt tttatcagac
     8221 gcaattgcgg atggtgcaaa tgttaaaggt tacttcatct ggtcacttat ggatgtcttc
     8281 tcatggtcaa acggatacga aaaacgttat ggactattct atgtagactt tgacacgcaa
     8341 gaacgctatc ctaagaaatc agctcattgg tataagaaag tagcagaaac tcaagtgata
     8401 gagtaatatt acttgaaaat gtaaaaaatt gttatccgat actttagaaa aagtacaaca
     8461 cttatttaga ccaggctttg aaaaggtata tattgttagt ttcgaagatt gtcctatgat
     8521 tcctgagctt gaagctaccc ccgttgctaa aatgtggtaa atggtatgtt ttaactggaa
     8581 aagagtggat ttgccattct gatttagagt tatcagcatt tgaatgggaa tttttacaat
     8641 cactcgatgt agaaatacgt gagactattc acttcgaggt aaattatttg cctttccaat
     8701 aataaaaaga aaggaattag ttgtgactat cgaattaaaa aacgagtatc ttactgttca
     8761 gtttaaaaca cttggtggtc aactgacttc gattaaagac aaggatggga tagagtatct
     8821 ctggcaagct gatccaaatt attggaatgg acaggcgcct attctatttc ctatctgtgg
     8881 tagtttacga aatgattggg ctatttatag acctcaagaa agaccttttt ttacaggtct
     8941 tattcgtaga catggttttg ttcgaaaaga agaatttatt ctggaagaag tcaatgataa
     9001 tagcgtgacc tttagtatta aaccaaatgc tgagatgctt gataattacc tatatcagtt
     9061 tgaactgaga gttgtttata ccttgaatgg taaatcaatt agaaccgaat ttcaggtaac
     9121 gaacttggaa atggaaaaaa caatgcctta ctttattgga gcccatccag cattcaattg
     9181 tcctttagta gaaggtgaaa actatgagga ttattatatt gaatttagtg aggttgagtc
     9241 ttgctcgata ccaaagagtt ttcctgagac aggattatta gatttgcaag atcggacacc
     9301 ttttttggaa aatcaaaaga ttctcgattt ggactactca cttttttccc atgatgccat
     9361 tacacttgac aagctcaagt ctcgtagcgt aacgcttcgg tcaaggaagt ctggtaaagg
     9421 tcttcgagta gattttgatg attttccgaa cttgattctg tggtctacaa ctaataaaag
     9481 tccattcatt gctttggaac cttggagtgg tctctccact tcacttgaag aaggtaattt
     9541 cttagaagat aaaagacagg taacgaaaat ttcacctcaa gaaacttcta gaaaaatcta
     9601 tgatattact atccttaatt aaaatttgtt attatttgag tcttcaataa gaattgaata
     9661 ctcttacctt gtgatgatag attggtcttc tccgtgccag tcttacatcg caaggttttt
     9721 aagttttttg tgggtctatg tcaactgtag tgggtgacga aaagctaaca tctaaagaca
     9781 gtctggtagt aaaaaaataa gattatttac tacttcttga tttaaa
//
LOCUS       DADVXB010000102         9826 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.104, whole genome shotgun sequence.
ACCESSION   DADVXB010000102 DADVXB010000000
VERSION     DADVXB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.104"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            167..1039
                     /locus_tag="KB902_002029"
     CDS             167..1039
                     /locus_tag="KB902_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6808821.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHTETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            1036..2994
                     /locus_tag="KB902_002030"
     CDS             1036..2994
                     /locus_tag="KB902_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6808822.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSDKA"
     gene            complement(3245..4096)
                     /locus_tag="KB902_002031"
     CDS             complement(3245..4096)
                     /locus_tag="KB902_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6808823.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            4219..4686
                     /locus_tag="KB902_002032"
     CDS             4219..4686
                     /locus_tag="KB902_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6808824.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(4949..5431)
                     /locus_tag="KB902_002033"
     CDS             complement(4949..5431)
                     /locus_tag="KB902_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6808825.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LSESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(5531..6394)
                     /locus_tag="KB902_002034"
     CDS             complement(5531..6394)
                     /locus_tag="KB902_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6808826.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            6992..7828
                     /locus_tag="KB902_002035"
     CDS             6992..7828
                     /locus_tag="KB902_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808827.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KN"
     gene            complement(8010..8351)
                     /locus_tag="KB902_002036"
     CDS             complement(8010..8351)
                     /locus_tag="KB902_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBB6808828.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            8437..9144
                     /locus_tag="KB902_002037"
     CDS             8437..9144
                     /locus_tag="KB902_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6808829.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            9131..9454
                     /locus_tag="KB902_002038"
     CDS             9131..9454
                     /locus_tag="KB902_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6808830.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            9552..>9826
                     /locus_tag="KB902_002039"
     CDS             9552..>9826
                     /locus_tag="KB902_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808831.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT         2981 a         1985 c         1786 g         3074 t
ORIGIN      
        1 ttgattacgt taacaataat tcgtttcatg tgactagatc atactaggca tgaaaaatct
       61 ctgaggaaca tggtttccct aggaggtttt tcgtgtctat ttttgtttgg ccgcaatcaa
      121 ctggtctagc aaacgtgaaa accaaatctt caaaaagggt gcgcgcatga aaatcaaaaa
      181 gatctttaat caaaatgcag tattggtaga tgacggtgga caggaaaaag tagctattgg
      241 aaaagggatt ggatttgaca gaaaaagaaa tgatttgatt tttgatcgtg atgtcgaacg
      301 gatatttgtc atggaaccag aaggtcaaat caagttgcaa aatttactta atcagattga
      361 tgaacgcttt ttatttgcag cagaaacgat cattgatcat acggaaactg ttttgatgga
      421 aaagttgaat gaacatgtat tgatcgcttt gaccgaccac attgcttttt ctgcggagaa
      481 cattaataac ggtatcgtca tccgcaacaa acttttaaga gaaatcgaag tgctttacag
      541 tgatgaattc agtattgctc aatgggcagt agagtatctg acaaaagagc ttgggattcc
      601 atatacttat gacgaagcag gatatatcgc aatccatatt cacagcggac gaagcggtcg
      661 gaacaataac catcgcagta tccgtgaagt gacgattgta tctgacatca tccatttagt
      721 ggaatcagaa ttggaaacag atatccattc agaaccattt tcactgaatt attcaagact
      781 ggtgaatcat ttacgactgc ttctacaacg aacccatgcg caacaatatg ctgttttaga
      841 cacggaaatc gtagaaatgg tcaaacgaaa atacccagaa agctataaga tttctaaaaa
      901 aatccgtgtg ttgctgacca aagaatacca gctcgcgatc acgaaagaag aactgggtta
      961 cttggccatc catatcgagc gtttaagaag cgcaatcgta caaacaaatg ttaacaatca
     1021 tgaggaggaa aaaaattgaa agcatatcta caacgaatgg gacgttccct tcaacttcca
     1081 gttgcggtct tacctgctgc tgctttacta gtagggatcg gaaactggtg ggcatcttat
     1141 agtaacgaca ttgtcgctca ttttttacaa gctggcggta acgcagtttt aggtcaatta
     1201 cctttgctgt ttgccgttgg gttagcacta gggatgtcag tggacaaatc aggtgctgct
     1261 gccttggcag gtttggtcgc atttgaagtt ccagtaaatg ttttaaaaac tgattcagta
     1321 gctactttat tgaatatcaa accagaatca gttgatccat cttttgctca gatcagtaac
     1381 gtatttattg gtattattgc cggattgatt gcggcagctc tttataatcg tttccacgaa
     1441 gcaaaattac cgatggcttt atctttcttt agcggcaagc gtctagtgcc aatcttggct
     1501 gcctttgtca tgttgctgat cagtgcagtg ctactgctcg tatggcctcc ggtttactct
     1561 gctttagttt cttttgctaa attcattttg agtttaggct ggggtggtgc aggtctttat
     1621 ggcttcttca accgtttact gatccctaca ggattgcatc aagcaatgaa ctccgtgttc
     1681 tggtttgacg tagcaggaat caatgatatt ggtaaatttt tggcttctga aggaacaaaa
     1741 ggcgtaacag gaatgtatca agctggattt ttcccaatca tgatgttcgg gcttccagca
     1801 ggagcatatg ctatttacag aaatgcacgt ccagaaaaca aagcaaaaac agcttccttg
     1861 atgctagcag cagcttttgc ttcattcttt actggtgtga cagaaccact tgaattttca
     1921 tttatgttcg ttgcttggcc attatatgtc ttgcatgcaa ttttcactgg gatttcttta
     1981 gcagtgagtg cattcttcca ttggacagca ggatttgcct ttagtgccgg atttgtcgat
     2041 tacttcctat ctttgaaaaa tccgattgcg aatcagccat tgatgttgat cgtccaagga
     2101 ttagtaacag cagtgattta ctactttggc tttaactttg ctatcaaaaa attccatctg
     2161 atgactcctg gccgcgagga agcagatctt tcagatgacg atactgcaac gactaattca
     2221 gacaataaat atgcggcaca agcaagcaaa atctacgctg cattaggcgg agccgacaat
     2281 gtaacttcga tcgataactg tactacacgc cttcgtttgc aagtcaaaga tacaggcctg
     2341 atcgatcaaa ataaaatcaa agccactggc gtacctggta tgaagatcat cgacggaaaa
     2401 aatgcgcaag tcatcgtagg tacagaagta caattcgttg cagatgagat ggcaaaacta
     2461 catggtggtg ctgcagcacg acctgcacaa acaaacaccg tggttaaaac agaaacattt
     2521 gccggtgaaa cgatcgaaca agatatttac gctatcgcaa atgggaaact gattccaatc
     2581 actgaagttt cagatgatgt attcgcggaa aaaatgatgg gtgacggcta tgctgtatta
     2641 ccagaaaatg gagaaatctt ctctccaatc gctggtacga tcacaaacat tttcccaacg
     2701 aaacatgctg tcggaatcca aacagatgct ggtatcgaag tcttgcttca tatgggcatc
     2761 aacactgttg acttaaaagg cgaaccattc actttatatg tagaagaagg tcaaaaagtc
     2821 gcaagaggtc aattgattgc tttagttgat cttgccgcta ttcaatctgc aggcaaaaac
     2881 acggatatgg tcgttgtatt cacaaatggc gacaaagtcc aaagcttaga aatcgaaccc
     2941 gcacgtgatg taaaagcaaa tgataaaatc ggctctgttt ccgacaaagc ctgagccatc
     3001 gtcttcccca gactttttta tcgataaaca aacaggagct gagacaaaaa tcttgtctca
     3061 gctccttttt ccgaataaaa acggcgttct cctgccaact ccgcggtaat aagtccagcc
     3121 aaacgaaaca tatgaagagc tattttttat ttgactcttc ttattacttg atgcagaaca
     3181 gctttttcac aaaatttttc ttcatactca aaactaatcg gctttttcac aacctcttta
     3241 tacattattc ctgatccaat atttctttta atgctgcttc aagagaagtt aatggttttc
     3301 ccaatacttt ttctaaatca tcagaggaaa tagctaactg atccttttta atatcatgtt
     3361 ggatcgctaa aaacatgtca gctgcttctt gagggaatcc ggcttctttt agattttcga
     3421 caaacgctgc atcacttgct tcaataattt ctaactcttt acctgtcgca cgctctaatg
     3481 ccttggctaa ttcttcatag tcagttagat tgccggataa ttctaagatt tctggagagt
     3541 cactttctac tagtactttt gctgcagctt ctgcatattc acgtttcaat gcccaacctg
     3601 tttttccatt tcctgcagca taaacgaatt gaccagtttt taaagcctgc ccaatgatag
     3661 gtaattcatt ctctacatac caattattcc gtaaaaatgt atgggaaata cctgaatcct
     3721 taatcatttt ttcagtgaat tggtgatctg gcgctaatac actgatcgag tgatcggcat
     3781 ctgcaaaact tgtataagcg atataagata ccccagctgc ttgtgctgcc ttcactacat
     3841 tcttatgttc ggcttgacga tttcctggaa cgccagagac aaaaagcaat cgatctattc
     3901 ctttcaacgc ttctttcatt gagtctaaat catcataatc accaatacgt atattaaatc
     3961 cagcttcttt cagtgcttct cctttttctt cactacgtac tagtacatag atttcatttt
     4021 gtggaaccat cttttttaag aattccagcg cataaccacc aaaacctcca gttgctcctg
     4081 ttactaaata atgcatattt gccactccct attcttttta tttgttaaga tttacagctg
     4141 tacatttata aattacacct ttatcataaa gagtgtggta agataagtca agcaaaaaaa
     4201 atgaaaggat gacaactgat gaagtattct ctgcaattta gtgatgcaat ccatgtactt
     4261 gcctatattg aaatgtttca agatacccga tcactttcta gtgagatgat tgccagtagt
     4321 atcgaaacaa atgcagcaaa tgtacgtaaa atcatgagtc agctcaaaaa atccggtttg
     4381 atctttacaa aaaccggaaa accgcagcct tcccttgcca aaagtccaga tcagatttct
     4441 ttactagatg tctatcgcag catcgaaggt aatacacagc ttatccaagt cgatccaaaa
     4501 acaaatccaa attgcgtcgt tggtgcgaat atccaagaag ctttagaaga aagctacgct
     4561 cggctgcaga aaaaggcaga agaagaaatg gctaagatca cacttgatag tctgatacat
     4621 aaaatagccg ttttggaaaa agaaaaaaga ccagaaaaca caggcctcgt agagagattt
     4681 ttataattct ctctactgtg cctgcatttt tctgatcgga atcgtctaca taaattcttt
     4741 tattctccgg gggacaaaag ccttgtcatg cccctttttc ctctctaatg ctcaggtcaa
     4801 agcgctgaag tcatgacgtc ttgataaacg gtgttcaagt agctgaccct cggcattagt
     4861 tctgaaaaat gcaaaatatg gaaagctatt tcccattttt cctctctaat gctcaggtca
     4921 aagcgctact ttcacgacct ctatattatc atggtttatt gactaccggt atccagattt
     4981 ctcccatata tttcccgttg gtaactccca tttcgactac agcatttgga cccccaacat
     5041 aggcgtaatc ttctacttct cttaaaacat gcccaaaggc cgtattcgtc aaatcatttc
     5101 ttaattcttc aggcgattct gataaagcgc ttacaacaag atacgttcct tttgggaatg
     5161 ggatgattcg cgtagtgttt ggaacatcct gactcgtttg aacaccgaca tagtacatca
     5221 ttttcccgtt atagggttcg ttgactgtaa agaaataatg attttcagca gcttgtttca
     5281 atgcatctat tgttccatta ccgataactt tttgctcaaa tgcttgtttc tctgcagcca
     5341 aaccgacaaa atccgtattg ctactcttca attccacacc aatacccgtc accgtaaaat
     5401 ctggtttttc ttcgatccta tactttgcca tttctcccac cctttctatt atattaagtt
     5461 catcttacat aaaattaaag ggaaatgaca cgattacgct cttttttcta gggatatttt
     5521 tattttttaa ctattttttt gctttcactg caatccaaat ctcactgtaa acattactga
     5581 aatcctctcc ccattttgta aaagagatct cgggagcttc gactaactca taatctgaag
     5641 aaggaagcca ttctgcatag attttccccc aagtatcttg taaagtttgg ggaaatggcc
     5701 ctttattagg aaaaatggcc caagtgtgtt cttctatagc aagcatttct aaatcagcgt
     5761 acggattttc ttttgtcgta gcaaagccaa tcatgtgcat caaactgccc ttttcttcca
     5821 agcggtctcc atcaaatcca taagaaacgt tgattacttg atttggatat aaatctccta
     5881 acttatgcat ctcttccctt tgagtctccg tgatcgtctg cgctaacttt tgtatttctt
     5941 gattgactcc ttcaaatttg acaggaactt ttttcgccac acctgccaca taaaactgtt
     6001 ctttcttttc gatacgaaat tccatcgatt ttcctcctct gacatcaata aaaaatgtca
     6061 agcgtggaaa agatttttgt atgccgtatc tgctgatttc tgaaggcaga tatcctgacc
     6121 aatcacgaaa agctcttgaa aaaccttcga ctgtttcata tccatatcta aacgccgttt
     6181 ctgtcactct tgatccatct agaagatcgc gattagccaa agccaatcta cggtttttga
     6241 tatagtccat tagcgacatc cctgcaataa acgtaaagat gcgttttaat tgatattcag
     6301 agattcctgt attttcggct attattttat aggaaagtcc ttctgtcaaa tgttcttcga
     6361 tgtaatcgat caattggttc agatctttaa gcatatttat cttcctcctt gcttgccttt
     6421 ttatcatatt atcaaagaaa gtcaattact tgatgaatca ggaaccaatt tagtcagatg
     6481 tagaaaatgt tgtatggatc taaagaaaat tctcaagcag cgtttcgtaa cggataattg
     6541 gtattatctg cctatctatg ttttaccttt agaaaaataa attttgggga agacagattc
     6601 taagtaaaca aagcggtaaa aatatctttt attcccttag ttaatccgct tactacctac
     6661 tgtacaaagc aaattgttgt tcaaactgct gatcagaacg ctgcttggat ttttctttgc
     6721 gatacatcat acctctttta tcaattggaa caattattta tttctaacaa aatcacttca
     6781 tttttgtcag ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta
     6841 ctttttctca cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa
     6901 agtgattatc aaatatgtaa agtcagctac ttttttctta aacgtttctt tatactaaat
     6961 ataaataagt gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga
     7021 aaacgttttg gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta
     7081 tacaagcaag tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac
     7141 ttgggatgaa aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg
     7201 caaacacatg gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta
     7261 ctcactttcc gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct
     7321 tttaacagag attcttatag aacatccgca ctttatcgaa cgcttcaaag ttaagatgcc
     7381 atttcatgca ataaattatt cagataaatt aacaactatc atccataaat acgatcatat
     7441 tatcaagaaa aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat
     7501 ccaagaagca gttgaatcgc ttattcagca aaatgcctat cttcccgcat tcgaattgat
     7561 caatgaagtg attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct
     7621 tcttctgata gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc
     7681 agaaaaaagg caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta
     7741 ttcaaaacgc tactccataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa
     7801 ccaaaagaaa aaaatagata aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa
     7861 aatagcaagt aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt
     7921 taaaaacacg aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag
     7981 tcatttgact attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct
     8041 ggatagattt tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga
     8101 ggttccactg catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac
     8161 caccctaacc ctagtgcagc aatcattgtt gcgcctaatg caggtccttc ctccacactt
     8221 aaacaataga ccgttgcatc gaaaatatca gcttggattt gtagccatgc aagatttttc
     8281 gcgcctcctc ccaccgaaac aatacgtgta aatctgcgac ccgctagttc tttacgtttc
     8341 aatcccacca ttgacaaatg ctcattaaaa atttagaata ttcacaagtt taacgacaat
     8401 tatgaaaatt tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt agatataaaa
     8461 actgcgatca aagacacgtt acctaccgtt ttcggttata tcggtattgg acttgcattt
     8521 ggtatcgttg ggaaagctgc cggatttcat ccactagtcg tcacgttgat gtccctgctg
     8581 gtctatgctg gttctgccca atttatcaca gtcagcatgc ttgctagtca cagcccattg
     8641 ctttccatcg ttttctcgac ctttctagtc aattcccgaa tgattctgat gagtatgacg
     8701 attgctcctt atttcaagaa aaatcggctg cttcaaaatc tgctgattgg cacattgctg
     8761 acagatgaaa gtttcgcact gggaatgaat aaattgaact atactggaca aaagttaaac
     8821 tttcgttgga tgaatacagc taattggatt tcttatttga cgtgggtggg ttcttctctt
     8881 gttggcgcac ttttagggaa ttttattact gatccgaaaa agtttggttt ggatttcgcc
     8941 atcgtcgcta tgtttatcgg gttactttat cttcaagtca tttctgatag aaacacctct
     9001 aaacgattac agttgatcct gattggtctc actttgattc tggtatatgt cggactgatt
     9061 tttatcccaa gcaacttagt gattgtagtt gtaacactga ttgggtgcgg attgggggtg
     9121 tggatcaaac atgccttctt ttgagtttac attgctgact attttaggtt gtactttagc
     9181 aacttggctt tctagggtcc taccatttgt cttactgaaa aaattcgatt taccgcaacc
     9241 gttgcttgag tatttaagtt ttgtcccgat cgtcattatg tctgctttat ggttcagcag
     9301 tctatttacc caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg ctttggcttc
     9361 agttcctaca cttttagctg ctattctttc aaaaagctta ttggtgatcg tcttggcagg
     9421 aattctttcc ctttcgttga ttcgcttatt ataaacgcga attgtaaaat taagttagaa
     9481 aaataaaaag gcatttatgg tacactcaaa ttgtatttcc gacgaaagaa aacaaaggag
     9541 tgtaaccata aatgacctac aaacatctta ccatagacga actgacaatg atagaatcat
     9601 attatcttca acataataag ccggttgaaa tcgctaaccg aatgggacgt gctatacaaa
     9661 ctatttataa tgtagtcaat aagttcaagc aaggcaagac tgctcttgat tattggcacc
     9721 agtataaaga aaataagaaa aaatgtggta gaaaagtcat tcaattacct gctcatgaag
     9781 tagattacat taaagagaaa gtcactcttg gttggacgcc tgacgt
//
LOCUS       DADVXB010000103         9796 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.105, whole genome shotgun sequence.
ACCESSION   DADVXB010000103 DADVXB010000000
VERSION     DADVXB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.105"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..205)
                     /locus_tag="KB902_002040"
     CDS             complement(<1..205)
                     /locus_tag="KB902_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808832.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(221..835)
                     /locus_tag="KB902_002041"
     CDS             complement(221..835)
                     /locus_tag="KB902_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBB6808833.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(982..1665)
                     /locus_tag="KB902_002042"
     CDS             complement(982..1665)
                     /locus_tag="KB902_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6808834.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1774..2232)
                     /locus_tag="KB902_002043"
     CDS             complement(1774..2232)
                     /locus_tag="KB902_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBB6808835.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2316..4079)
                     /locus_tag="KB902_002044"
     CDS             complement(2316..4079)
                     /locus_tag="KB902_002044"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBB6808836.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4300..5760)
                     /locus_tag="KB902_002045"
     CDS             complement(4300..5760)
                     /locus_tag="KB902_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808837.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5968..6894)
                     /gene="glsA"
                     /locus_tag="KB902_002046"
     CDS             complement(5968..6894)
                     /gene="glsA"
                     /locus_tag="KB902_002046"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBB6808838.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6917..8344)
                     /locus_tag="KB902_002047"
     CDS             complement(6917..8344)
                     /locus_tag="KB902_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6808839.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8375..9589)
                     /locus_tag="KB902_002048"
     CDS             complement(8375..9589)
                     /locus_tag="KB902_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBB6808840.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         2903 a         2040 c         1625 g         3228 t
ORIGIN      
        1 atttgttaaa gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac
       61 catctaaagt aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact
      121 gcccttgcag aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg
      181 atggtttata gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg
      241 tgaaaatttc tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt
      301 ttcttggatc gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct
      361 gtacttctag caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt
      421 catataagga tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta
      481 ctgaatcagt taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg
      541 ctgctgtttt atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc
      601 ttgtctcaag aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca
      661 aggataagat gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca
      721 ctatatcttt tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa
      781 tcagcaactt gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt
      841 cgccttcttt ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg
      901 cttttttcat cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag
      961 aatctgtgcc gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt
     1021 agtgatcaat tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc
     1081 atatgctttc tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc
     1141 gacttgttct atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata
     1201 ttctgtatag cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag
     1261 cgcttcctca aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg
     1321 gacaagttca gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat
     1381 gatttctgct tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac
     1441 ttctgaccca tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt
     1501 gatttcattg atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc
     1561 agccaaagcc attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg
     1621 acaagaaacg acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt
     1681 aatgttatat aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa
     1741 taatgagcta tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc
     1801 gtatacgacc agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt
     1861 aaaaaactca gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt
     1921 ccaagcatgc tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat
     1981 gatacaaact ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa
     2041 aggctcattc tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt
     2101 tacaactagt tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc
     2161 taatttttct gattgataac taggatattt ttcttggaac tttttgacat attcttctac
     2221 ttgctgatac ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta
     2281 gtataaacaa ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga
     2341 ctatcttcaa cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga
     2401 acgctatccg tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca
     2461 taataacgac tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg
     2521 actaattcgt gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt
     2581 cctggattga tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt
     2641 cctaattcaa gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt
     2701 tgataggctg gaatactata atcatttgcg atagctgtac catgttctac accatgtgta
     2761 ggaattcgga ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc
     2821 atatcctctt ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga
     2881 atgtcaaatg ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa
     2941 ataatcactg gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc
     3001 aagaaagtac ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg
     3061 aaagtgatag agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct
     3121 tggaatgttt tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct
     3181 gtacttgttt gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca
     3241 gaagttactt gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc
     3301 attttattat cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca
     3361 atcggatgat caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt
     3421 ccattatcca cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta
     3481 ccgttggttt gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata
     3541 gacatctcat tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc
     3601 aatccttcaa aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt
     3661 cctgattctt tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta
     3721 gatgtgtgcc ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc
     3781 acttcacggt aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca
     3841 taagactgat gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga
     3901 aacgcaatcg ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg
     3961 tccttttgca agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat
     4021 aattttttga catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata
     4081 atacattctc tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct
     4141 attctactac ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc
     4201 ttgttatata agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa
     4261 ttaaaaagct ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa
     4321 taggtgaagt tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg
     4381 atagatcttt gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac
     4441 cactcttttt ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat
     4501 aggatttatt tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa
     4561 ttgtttgact gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc
     4621 actgttgatc aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag
     4681 ttggatttga tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag
     4741 ttgttctttt tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca
     4801 caacgtacgg acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat
     4861 ttcagcgata ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa
     4921 atttttataa acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt
     4981 tctactgttg aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc
     5041 tttttgctct tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt
     5101 cttatcttct tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc
     5161 tcgtatgata aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac
     5221 ataatcaatc aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc
     5281 ccaattgaca taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat
     5341 gatttcttta tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat
     5401 tgtatatact ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat
     5461 accattaaaa taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt
     5521 gagctcagaa agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac
     5581 ttgttctttt atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt
     5641 tggtgtagtc acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa
     5701 taattgttca cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat
     5761 tcctgataca cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat
     5821 ttttgtttcc tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga
     5881 caaaagtcaa acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac
     5941 ttttacccca gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac
     6001 tacatctttc aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct
     6061 gaagacacct atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct
     6121 ttttgcaggt acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt
     6181 tgtcataatt gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca
     6241 aggagcaatt cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac
     6301 attgagggag cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat
     6361 ttgattacct ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga
     6421 atgatagatt tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga
     6481 caagattcgc tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat
     6541 cgctcctgca ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat
     6601 gatagaattg aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat
     6661 tccgttgtct ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa
     6721 gcgcacatcg gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat
     6781 acctaattgt ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt
     6841 ttgataatag tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat
     6901 aaccagcttt cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg
     6961 taaatggaat aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat
     7021 gctgtccagc tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag
     7081 tcaaaagacc taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg
     7141 ctctttcaag actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt
     7201 acaacatcag gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc
     7261 ccccgccgct taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca
     7321 tcaaatgagc aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt
     7381 cttctgctgc tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga
     7441 tgacacctaa acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa
     7501 tgtgtcttaa taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt
     7561 gaggtactgt agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa
     7621 ccaatacaaa cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac
     7681 tggcagatgt ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag
     7741 gcaatttcga aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc
     7801 ctgaagcgac ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag
     7861 ctacaaaacc gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta
     7921 aaatagccca gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag
     7981 caccaatacc cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc
     8041 caactgttat ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg
     8101 tgcgactgac ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg
     8161 ctgcgcacaa tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta
     8221 agctgaagcc tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg
     8281 tcatagccaa aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt
     8341 gcatgaatct tcctcttttc tatttgaatt tgtttcaatt gagtttgttg ccaaagaaga
     8401 aaaagtccaa tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg
     8461 ccgattttaa aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa
     8521 tcacttgaat ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg
     8581 caaagatccc tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat
     8641 caagtgcatc atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac
     8701 ccgcaatgat cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa
     8761 tggctgccaa tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt
     8821 ttacttttgc aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac
     8881 caaatgcatt gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc
     8941 agccaaacca aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc
     9001 tttctcctaa aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc
     9061 cagctgtcgt gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa
     9121 atccgccacc ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa
     9181 caagtataat atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa
     9241 cggtaatcac gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac
     9301 catgaaacat gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc
     9361 caataacacc gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa
     9421 tcgttgttat cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc
     9481 gtgctaatcc gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac
     9541 ataaaatcat gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct
     9601 cctttctacg attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga
     9661 attaatactt gcatttataa aagacagaca attaataaaa gcttgatgtg ttgtgctctt
     9721 tttcgttttt cacacaaata aagacaaaaa ataaacggtc ttctttttat agaaaaccgt
     9781 ttattttcgt cttttt
//
LOCUS       DADVXB010000104         9765 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.106, whole genome shotgun sequence.
ACCESSION   DADVXB010000104 DADVXB010000000
VERSION     DADVXB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.106"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(193..1041)
                     /locus_tag="KB902_002049"
     CDS             complement(193..1041)
                     /locus_tag="KB902_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6808841.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1040..2107
                     /gene="gnd"
                     /locus_tag="KB902_002050"
     CDS             1040..2107
                     /gene="gnd"
                     /locus_tag="KB902_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBB6808842.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            2109..3110
                     /locus_tag="KB902_002051"
     CDS             2109..3110
                     /locus_tag="KB902_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBB6808843.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3107..3391
                     /locus_tag="KB902_002052"
     CDS             3107..3391
                     /locus_tag="KB902_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBB6808844.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3424..4221
                     /locus_tag="KB902_002053"
     CDS             3424..4221
                     /locus_tag="KB902_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6808845.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4235..5068
                     /locus_tag="KB902_002054"
     CDS             4235..5068
                     /locus_tag="KB902_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6808846.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5086..5943
                     /locus_tag="KB902_002055"
     CDS             5086..5943
                     /locus_tag="KB902_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6808847.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5965..6474
                     /locus_tag="KB902_002056"
     CDS             5965..6474
                     /locus_tag="KB902_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808848.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6511..6912
                     /locus_tag="KB902_002057"
     CDS             6511..6912
                     /locus_tag="KB902_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808849.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7024..7377
                     /locus_tag="KB902_002058"
     CDS             7024..7377
                     /locus_tag="KB902_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808850.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7411..7854
                     /locus_tag="KB902_002059"
     CDS             7411..7854
                     /locus_tag="KB902_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6808851.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7871..8956
                     /gene="uxuA"
                     /locus_tag="KB902_002060"
     CDS             7871..8956
                     /gene="uxuA"
                     /locus_tag="KB902_002060"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6808852.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8949..9662
                     /locus_tag="KB902_002061"
     CDS             8949..9662
                     /locus_tag="KB902_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6808853.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         3238 a         1547 c         2162 g         2818 t
ORIGIN      
        1 actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt ctccaaagat
       61 gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct tgcagaacca
      121 aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt tttcgctttt
      181 tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag cgatagaacg
      241 acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca aaatgcttag
      301 ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag aaatagaaat
      361 aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa taacgattgt
      421 ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg attgccctgt
      481 gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca tcaattgaat
      541 atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat gataagcgtc
      601 agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag attcattgat
      661 aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt catttaaagt
      721 tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg ttttctgaat
      781 attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg ccattttaaa
      841 atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag agtcagcaat
      901 gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg gattttctaa
      961 aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg ttttgatttg
     1021 tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta tcattttttc
     1081 cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa aaaatatttt
     1141 tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa atggaggcgc
     1201 tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag ctttaaactt
     1261 aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg ttagtcaggc
     1321 aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta cttttgagca
     1381 gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca tgttaagaaa
     1441 actttttcca aaactcggac caggagacat tattattgaa ggcggaaact cttattataa
     1501 agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact tggattgtgg
     1561 gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg gaggagataa
     1621 agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa gaggatatct
     1681 gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg gaatcgaata
     1741 tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg agtatgcttt
     1801 tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg gctggctgat
     1861 ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc ggggaatcgt
     1921 ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg ctgttccagt
     1981 tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag atagtttttc
     2041 agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag ttgaaaaggg
     2101 tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc ggaagagtct
     2161 ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt actgttgatc
     2221 aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc attattgcaa
     2281 gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg ctattgattt
     2341 cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa caccagacaa
     2401 tcgtatctat catacctgct ttagttgaac gaaatgctgt agcagaaaat aatataacta
     2461 atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag gacgatcgat
     2521 gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt ggtgtgattg
     2581 gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt cgctgtgatg
     2641 ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt gcaaaaaaag
     2701 tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg aatttgacag
     2761 aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa aatgtttatc
     2821 tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat ggtctgaaaa
     2881 gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga cgtcaagatc
     2941 atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc tacacaaggg
     3001 aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc agtcagcacc
     3061 ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga tgaagaaaat
     3121 ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag aaggtggtat
     3181 ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg tcacccacgg
     3241 aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg aaacgattca
     3301 atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac gaatagctac
     3361 aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa actgaccgat
     3421 ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc tactttagct
     3481 agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg acaagcagaa
     3541 gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc ccaattagtg
     3601 attgattccc ctgttccata tttcattgcc gggttagcag atacactagc aaaatggtat
     3661 gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt gaagctagca
     3721 caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa agcaatccaa
     3781 gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat tatctttgct
     3841 gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc agcacatgct
     3901 atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca tggagaaaaa
     3961 gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa aatagacgag
     4021 ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat gggattattt
     4081 ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa agagaaagtg
     4141 catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat ggaactggaa
     4201 ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg tagtacaaag
     4261 tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg gaggagccac
     4321 gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga tcatggggga
     4381 agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg gggttttttc
     4441 tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag taccagtcgc
     4501 attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag tcggattgct
     4561 cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta aatatacaga
     4621 caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc tttatccaac
     4681 ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt taggggcgcc
     4741 attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca ttcttgaagt
     4801 agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta tcggtcgaaa
     4861 agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga aatctttaga
     4921 tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct ttgtccagtc
     4981 gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat cttttgatga
     5041 cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc tgaaataatg
     5101 gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa agcctatctg
     5161 agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc gccatcacta
     5221 ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc tttaaaagca
     5281 gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg cggtgtgatt
     5341 actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga agaaaaagag
     5401 atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg ggcactagca
     5461 ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc aatcgcggta
     5521 ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg ctttgggttg
     5581 tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg ccgtaatgct
     5641 acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc agttttaggg
     5701 ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc attgaaattt
     5761 gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt gccagggata
     5821 ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg attgaaagtc
     5881 acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat cggtatttta
     5941 taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt ggatgagcgt
     6001 ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa ttccattttt
     6061 gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa aaatgcagga
     6121 agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt ctattgggat
     6181 gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca aacgatttac
     6241 gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat tgctcaaaaa
     6301 aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc agatgctgaa
     6361 aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca agccactcca
     6421 tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc ataaacaaat
     6481 gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt tcgtgattgg
     6541 gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa acagcgtttt
     6601 ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt cattgcttac
     6661 gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa agcagagaaa
     6721 gttatctgta cttattacga tacacccgtt catgcattag gaagttattt catgtttgat
     6781 tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat tttgttgttc
     6841 agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt attcgatctg
     6901 ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt cttattggga
     6961 aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc atccatatta
     7021 acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc gtttgttgat
     7081 gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa aaaagaggct
     7141 attctttttt atctagactc tgttggggca gatacaccgc tacagttttc gggaaattat
     7201 ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa aaacgtcaat
     7261 tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa aacagattta
     7321 cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt tcgataagta
     7381 aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt tacacatggt
     7441 aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc gagccatatt
     7501 gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa ggtcaaagaa
     7561 aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct aattagcgca
     7621 agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa gaaagcagcc
     7681 acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa tcatcagatg
     7741 cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa agataattta
     7801 actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt ttagaaggaa
     7861 ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt cgatcccatt
     7921 aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc tgactaaaat
     7981 gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg ttgagagcca
     8041 aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca aggcagggac
     8101 agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact tgtctcgatg
     8161 tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga aaactgattt
     8221 gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa tcgtcgatca
     8281 gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat tcaaattgcc
     8341 gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt atgaaggaat
     8401 gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga ttccagtgtg
     8461 cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg aactttttgg
     8521 ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg cagtagattc
     8581 tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg aaaacgattt
     8641 agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca gaaacgtgga
     8701 gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag gctcccttga
     8761 tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta tacgccctga
     8821 tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt atgatcgtgc
     8881 aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa aaccactggg
     8941 agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt ttattagaaa
     9001 ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat tatgaaatgc
     9061 gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga gaacaaatgg
     9121 gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc aatcaatata
     9181 aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca gaagaaattt
     9241 tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat acacgggtaa
     9301 aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa atcatttcag
     9361 gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct tgttcaaaaa
     9421 tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg atcgaagcag
     9481 caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg ttgcccgatc
     9541 ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat aaagcagact
     9601 atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg ttgtatctct
     9661 aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact gagggaacag
     9721 atgaaaaaga agtaattttt tattttgaag tatctacctt atttg
//
LOCUS       DADVXB010000105         9759 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.107, whole genome shotgun sequence.
ACCESSION   DADVXB010000105 DADVXB010000000
VERSION     DADVXB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.107"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..418
                     /locus_tag="KB902_002062"
     CDS             <1..418
                     /locus_tag="KB902_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6808854.1"
                     /translation="QIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSI
                     QQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKN
                     QFHQAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            588..848
                     /locus_tag="KB902_002063"
                     /pseudo
     CDS             588..848
                     /locus_tag="KB902_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1011..1676
                     /locus_tag="KB902_002064"
                     /pseudo
     CDS             1011..1676
                     /locus_tag="KB902_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            1712..1957
                     /locus_tag="KB902_002065"
     CDS             1712..1957
                     /locus_tag="KB902_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6808855.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2060..2929
                     /locus_tag="KB902_002066"
     CDS             2060..2929
                     /locus_tag="KB902_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBB6808856.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2910..3644
                     /locus_tag="KB902_002067"
     CDS             2910..3644
                     /locus_tag="KB902_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6808857.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            3677..4585
                     /locus_tag="KB902_002068"
     CDS             3677..4585
                     /locus_tag="KB902_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBB6808858.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            4582..5124
                     /gene="sat4"
                     /locus_tag="KB902_002069"
     CDS             4582..5124
                     /gene="sat4"
                     /locus_tag="KB902_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBB6808859.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5217..6011
                     /locus_tag="KB902_002070"
                     /note="aph(3')-IIIa"
     CDS             5217..6011
                     /locus_tag="KB902_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBB6808860.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6287..6859
                     /locus_tag="KB902_002071"
     CDS             6287..6859
                     /locus_tag="KB902_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6808861.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            7157..8053
                     /locus_tag="KB902_002072"
     CDS             7157..8053
                     /locus_tag="KB902_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6808862.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            8152..8361
                     /locus_tag="KB902_002073"
     CDS             8152..8361
                     /locus_tag="KB902_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6808863.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            8378..8650
                     /locus_tag="KB902_002074"
     CDS             8378..8650
                     /locus_tag="KB902_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6808864.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            8652..9515
                     /locus_tag="KB902_002075"
     CDS             8652..9515
                     /locus_tag="KB902_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6808865.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
BASE COUNT         3482 a         1486 c         2001 g         2790 t
ORIGIN      
        1 acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc tgattgttga
       61 agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc tcttgcacac
      121 tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa
      181 agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag ataaatattg
      241 gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac
      301 taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa gtaccgttac
      361 ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga ggaaataatt
      421 ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat ggagataaat
      481 tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg cctacgggga
      541 atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt gtaggaaaat
      601 gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt tcaaattatc
      661 ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc aaaacgaatg
      721 taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac aaagagaaaa
      781 agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt atctcttttt
      841 caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga ggtctttcca
      901 tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa aaataaagca
      961 cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc atgtatcaaa
     1021 attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta gaagaaaatg
     1081 attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc tttcttcctt
     1141 attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc attattcttt
     1201 gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg atagatagta
     1261 ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt aatcgttttc
     1321 gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt cgtgagctac
     1381 tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca aaaattgaag
     1441 cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat aaggatagcc
     1501 ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc ttacctgagt
     1561 taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt cgtcaatctt
     1621 tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca gtagaagggg
     1681 gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc tattggaaga
     1741 agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta aagatttatt
     1801 caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg gaacgttatt
     1861 tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga cttcatctaa
     1921 tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga aattaaaaaa
     1981 attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca gcagtgaatc
     2041 gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag agaaattatc
     2101 ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg gcacccatac
     2161 agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg acataaatac
     2221 tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg ttgtacctcc
     2281 cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg ggtatcatgt
     2341 ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata cagagcacgg
     2401 aattgttact gccaattatc agactgggca tccccatggt tatattagtg caatgtatcg
     2461 aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat gcgaattaaa
     2521 aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact tttttatgtt
     2581 tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg ataaatatta
     2641 tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat ttgcatgtaa
     2701 taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt ttgaacataa
     2761 acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta tctcactttt
     2821 tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg tatcggagat
     2881 aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat gataatatat
     2941 tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt gcgggagaat
     3001 gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt gatttaggat
     3061 gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct gtagtaggtg
     3121 ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt ccacagattg
     3181 aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt gatgtaatac
     3241 taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa aagatatata
     3301 ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt tttactgctc
     3361 atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc ccggtggaca
     3421 attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt acaaaatatc
     3481 atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata ataaatcaga
     3541 ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg gatgaaatgc
     3601 gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat agaaaaaata
     3661 aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac tttctttagc
     3721 agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa atattaatat
     3781 acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata tagaaccgtt
     3841 tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc aaaagccgga
     3901 ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc tatttgatga
     3961 ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt acctaaaggg
     4021 cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg acatagttcc
     4081 gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg attgctgcaa
     4141 tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg aaattttatt
     4201 tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga tatcatggaa
     4261 ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt ttattgaaag
     4321 gtatatatcc gaggatttgt gggagaaact tttgtccacc taccggatgg attcctatga
     4381 aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat ccggtgaggt
     4441 ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa aatataccag
     4501 ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat atgccgctga
     4561 tatagaagag aggcgggaac agtgattaca gaaatgaaag cagggcacct gaaagatatc
     4621 gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta tgaaaacgag
     4681 aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta ccaagacgaa
     4741 gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac tgataagata
     4801 atatatcttt actaccaaga cgataaatgc gtcggaaaag ttaaactgcg aaaaaattgg
     4861 aaccggtacg cttatataga agatatcgcc gtatgtaagg atttcagggg gcaaggcata
     4921 ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc ataaaaactt gcatggacta
     4981 atgcttgaaa cccaggacaa taaccttata gcttgtaaat tctatcataa ttgtggtttc
     5041 aaaatcggct ccgtcgatac tatgttatac gccaactttg aaaacaactt tgaaaaagct
     5101 gttttctggt atttaaggtt ttagaatgca aggaacagtg aattggagtt cgtcttgtta
     5161 taattagctt cttggggtat ctttaaatac tgtagaaaag aggaaggaaa taataaatgg
     5221 ctaaaatgag aatatcaccg gaattgaaaa aactgatcga aaaataccgc tgcgtaaaag
     5281 atacggaagg aatgtctcct gctaaggtat ataagctggt gggagaaaat gaaaacctat
     5341 atttaaaaat gacggacagc cggtataaag ggaccaccta tgatgtggaa cgggaaaagg
     5401 acatgatgct atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac tttgaacggc
     5461 atgatggctg gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc tcggaagagt
     5521 atgaagatga acaaagccct gaaaagatta tcgagctgta tgcggagtgc atcaggctct
     5581 ttcactccat cgacatatcg gattgtccct atacgaatag cttagacagc cgcttagccg
     5641 aattggatta cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac tgggaagaag
     5701 acactccatt taaagatccg cgcgagctgt atgatttttt aaagacggaa aagcccgaag
     5761 aggaacttgt cttttcccac ggcgacctgg gagacagcaa catctttgtg aaagatggca
     5821 aagtaagtgg ctttattgat cttgggagaa gcggcagggc ggacaagtgg tatgacattg
     5881 ccttctgcgt ccggtcgatc agggaggata tcggggaaga acagtatgtc gagctatttt
     5941 ttgacttact ggggatcaag cctgattggg agaaaataaa atattatatt ttactggatg
     6001 aattgtttta gtacctagat ttagatgtct aaaaagcttt aactacaagc tttttagaca
     6061 tctaatcttt tctgaagtac atccgcaact gtccatactc tgatgtttta tatcttttct
     6121 aaaagttcgc tagatagagt tctatattag agatgtaaag agttttggtg aagaggtttg
     6181 tgagtatggc ttttataacc agggtgcaat gagaagcact aacagcagct agcttaagaa
     6241 cgcataggat atacttttta tggaagtcac agaggaggaa taaaatttga acaggattaa
     6301 cagagtaacc tctattctta ttcagctgca atcaaaaaaa ataattcctg ccaaagaaat
     6361 tgcacagcga tttaatataa gcttaaggac agtttacaga gatatccgga cacttgaaga
     6421 agccggaata ccaattggat ctgaggccgg aaaaggatat tttcttgtag agggcttcct
     6481 acttccgccg gtaatgttta cagcggcgga agtgggtgca ttgattacag cagggaaatt
     6541 tttaaattgc catggagatg aatcatttat aaaggatttt gattcagcta tgtataaaat
     6601 caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag gagttggaga acagtattaa
     6661 cgtgtacagc acatctggac agaaaaatac attggcggat aacgttattg cagcaattca
     6721 gactgcaatc tgcaataaaa gggtaatatc aattcaatat cctgcatcag gagggcaaga
     6781 accggaaagc agaatgatag agcctatatc actggggttt tatgaacaga actggtactt
     6841 aatcggtttt gcaggctaag aaatgaatat aggaattttc gtgtggatcg gattaaaagc
     6901 atttgcatag aagaagagct ctgtcaaagc catgatggct ctttggaaca aatattaaaa
     6961 caaatgcttt catataaaaa actatatgcc ctacaatgcc gttgtaaaaa ttggggaaaa
     7021 gggatatatt gattttatat ctttctcaaa ataaatataa aagcccttta aagagggctt
     7081 ttatatatta atcacaaatc acttatcaca aatcacaagt gattaatcac aaatcacttg
     7141 tgatttgtga ttcttaatga tacaatatta ctatacaaaa aaagaatggg gcgtagttat
     7201 ggagaaggaa aaactaaaaa tacttgaaga attaagacgt attttaaaca ataaaaatga
     7261 agcaattatt atcttgaata attactttaa aggtggtgtt ggaaagtcca aattatcgac
     7321 tatgtttgct tacttgacag acaaattgaa tttaaaagtt ttaatgatcg ataaggactt
     7381 acaggcaaca ttgacaaaag acttagcaaa aacttttgag gtagaattgc cacgtgtcaa
     7441 tttttatgaa ggcttgaaaa atggaaactt ggcttcttct attattcatt tgactgataa
     7501 tttagacttg atccctggca cgtttgattt gatgttactg ccaaaattaa ctcgctcatg
     7561 gacgtttgaa aatgaaagta gattgcttgc tactctttta gcacctttaa aaagtgacta
     7621 tgatcttatt attattgata ctgtaccaac gccaagcgtt tatacaaata atgcaatcgt
     7681 ggcgagtgat tacgttatga tccctttaca agcagaagaa gaaagtacaa acaacattca
     7741 aaactatatt tcctatttga ttgatttgca agaacagttt aaccctggac tagatatgat
     7801 tggttttgtt ccttatttag ttgatacgga cagcgcaacg ataaaatcaa acctggaaga
     7861 actgtacaaa gaacataaag aggataattt ggttttccga aatattatca agcgaagtaa
     7921 taaagtaagt acttggtcta aaaatggcat tacagaacac aaaggctatg acaaaaaagt
     7981 tttgtctatg tatgagaacg tattttttga aatgattgag cgaatcattc aattagaaaa
     8041 tgaaaaagaa tagaatcaca aatcacaagt gattaatcac aaatcacttg tgatttgtga
     8101 taggtgatga taaaataaat agtaagaaga aatagaaaga agtgagcgat cgtgggaaat
     8161 ttaggcgcac agaaagcaaa acgaaatgat acgccaatca gcgcaaaaaa agatataatg
     8221 ggggataaga cggttcgtgt tcgtgccgac ttgcaccata tcataaaaat cgaaacagca
     8281 aagaatggcg gaaacgtaaa agaagttatg gatcaagcct tagaagaata tatacggaaa
     8341 tatttacctg acaaacttta aaaggagtga aaatgaaatg gcagttacgt atgaaaaaac
     8401 atttgaaatt gaaatcatta atgagttatc ggcaagtgtt tataatcggg tattaaatta
     8461 tgttttgaat catgaactag atactaaaaa tactcgttta ctagaagtga atcttttaaa
     8521 tcaattagaa gtggcacaag aagttgattt atttcaacaa ccatttgaag aattacaagc
     8581 tattcatgag tattggcggt caatgaatca atattcaaaa caaattttga ataaagagaa
     8641 agtggcttaa catggcgaat attactgact tcaccgaaaa gcaatttgaa gatcgtttag
     8701 aaaagaatgt tgaacgacta actaaaaata gactagcggt tgaatcgcca accgcttttt
     8761 tacttggtgg gcaaccaggg tcagggaaaa ccagtttgcg atcagcaatt tttgaagaaa
     8821 cacaagggaa tgttattgtc attgataatg atacctttaa acaacagcac ccaaattttg
     8881 acgaattagt gaaactctat gaaaaagacg tagtaaaaca cgttacccct tattcgaatc
     8941 gcatgacaga agcacttatt agccgtttaa gcgatcaagg ctataattta gtgattgaag
     9001 gaacaggacg aacaacagac gttcccattc aaacagccac aatgcttcaa tctaaaggtt
     9061 atgaaacaaa aatatacgtc atggcagtac cgaaaattga atcatactta ggaacgattg
     9121 aacgatatga aaccatgtat gcagatgatc caatgacagc tagggcaaca ccaaaacaag
     9181 cgcatgatat tgttgtcaaa aacttaccga ccaatttaga aacccttcat aaaacgggct
     9241 tatttagcga tataaggctt tacaatagag aaggagtgaa actctattca agcttagaaa
     9301 cgccttccat tagtccgaaa gagaccttag aaagagaatt aaatcgtaaa gtatcaggga
     9361 aagaaattca accgactttg gagagaatag agcaaaaaat ggttcaaaat caacaccaag
     9421 aaacccctga atttaaagca attcaacaaa aaatggaaag cttgcagcta cctacaccac
     9481 caatacccaa aacacctaaa cttccaggta tttaaacctt aaaaaaggaa aagagtagtt
     9541 accaaaaaac ggtaactact ctttttttat aaaaacattt cctcatgttg gggtcccgag
     9601 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg tttttttcta
     9661 atttcatttt gaggtgaatt aattggtagt tattagaggt gccctatacc taataattta
     9721 tctacattcc ctttagtaac gtgtaacttt ccaaattta
//
LOCUS       DADVXB010000106         9735 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.108, whole genome shotgun sequence.
ACCESSION   DADVXB010000106 DADVXB010000000
VERSION     DADVXB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.108"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            29..508
                     /locus_tag="KB902_002076"
     CDS             29..508
                     /locus_tag="KB902_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808866.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            541..2769
                     /locus_tag="KB902_002077"
     CDS             541..2769
                     /locus_tag="KB902_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6808867.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            2898..4541
                     /locus_tag="KB902_002078"
     CDS             2898..4541
                     /locus_tag="KB902_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6808868.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4614..5159)
                     /locus_tag="KB902_002079"
     CDS             complement(4614..5159)
                     /locus_tag="KB902_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBB6808869.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5182..5667)
                     /locus_tag="KB902_002080"
     CDS             complement(5182..5667)
                     /locus_tag="KB902_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6808870.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5657..6469)
                     /locus_tag="KB902_002081"
     CDS             complement(5657..6469)
                     /locus_tag="KB902_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBB6808871.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6608..8140)
                     /locus_tag="KB902_002082"
     CDS             complement(6608..8140)
                     /locus_tag="KB902_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBB6808872.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8249..9280)
                     /locus_tag="KB902_002083"
     CDS             complement(8249..9280)
                     /locus_tag="KB902_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6808873.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3242 a         1805 c         1884 g         2804 t
ORIGIN      
        1 aaaaataaaa ggatgaggag ttaaaataat ggaaatacca acaaatttaa aacataaacc
       61 agtaatcgtt gtagaagact atgataaagt tgatggaaga aatgcattaa atatggatgc
      121 aaaagggctt tcactgggcc ttgctcagtg gaatgatcgt ggaaaagtcg atatctcagg
      181 caaggtatgg cgacatactg gagaaaaatg gtcacgacag tcggaagaat taccaatcac
      241 acgtatttta gatttagcga tcttagctgc gcaaggaagt ttatacttcc aagatgctta
      301 tcgttatgaa aaattttatg atccagaaaa tccagtcgta gacatcattg gattacaagg
      361 gaaccgaatg acggtagaag tagataccaa aaatccaaag atcgatgaag acatcatttt
      421 gtattacgat acactacaaa aagacggaga actgattggg gaacgattcc gtattttaaa
      481 acgtctttta gatgagctag gatattaata gacagagatg atcaaaaggg gaagagaagc
      541 atggagaatt tctcactaac agaaaaccga accttttcac ggctagaaaa gcaaatgatc
      601 tggaagaaac cgaaaagcca tcggacaagt gcagaagaat ggcggatcgc ctccgaaatc
      661 aaagggaatt ggcaagatcc tgaaatgaaa atcagtaacg tacttttgga aggagatgcc
      721 gggtcgggga agacacaatt agccaaagca ctatctgctg atctgcaact tccctataca
      781 aaagtgacct gttttgcaga tatggacaaa tcagatgttt tcggagcctt attacctgta
      841 gtagattcta ataaggaaca agaccaagaa ttactagaag ctatttacca aacagataca
      901 cttgaagctg tactgacact gatccagaac cattacggca ttgatccttt ttctgctaaa
      961 gaaaaattag cagagctagt tcaaaggatc gaagctgatt atccagatgc aatccattac
     1021 agctattacc cttctgaaat cgttcgagcg attgaaaaag gctatttatt agagattcaa
     1081 gagccgactg tcatccgaga tgcctctgtt cttgtggcac ttaactcagc gctcgaacca
     1141 aatgggatgt tgaatttacc gacaggaatc attcgtcgcc atccagattg cgtcattgtg
     1201 atcactacaa atcgaaatta ccaaggaaat cgcccattaa atgaatcttt aagagatcgg
     1261 atgcaacatg cggaaaaaat ggatcttcct gccttagaag tcatggcaga acgtgcgatg
     1321 gcgaaaacta tgatccaaaa acaagaactt ctcttaaaga tggcagagat tatccgtttg
     1381 ttggatgaaa ctgcaaaagc taacgccatc aaaggtgtag caggaatgcg ttcttatttt
     1441 tattgggcaa atacctataa gcaaggacaa gatttactcc agtcgattta tccaaaagtt
     1501 ttgtataaat tatccactga ttcagatgaa ttggcaattc ttgaacaagc tttgtctgac
     1561 agtggattgc tactggaact tcaggacata ttgagaaaag aaaaatgggg tcatcctcaa
     1621 tctgagcata caaaagaaag aaccattagc gccgaagaag caaatgaacg aaacatcact
     1681 gaaaatgctg aagaaattct gcgcttagat gaaaagaaat cgttgtctgc tgaagaacca
     1741 aatgagggag aagagaaaca agaagaaaca atagaaaaaa acgagattcc tcctcaaatg
     1801 caaaaagaac gcagtagcga tatcgaagga aaaaatcaaa aagaacaaca aacaggagat
     1861 gattctcaag aaatgtctgc ttctgacatg gaagcacatg ataaggaaat caagaagcaa
     1921 ctgaataaag aagcgcgaca aatcatgaag gaaacgattc atgaaaaaga aggtctcatc
     1981 gttcaccgac cagctttcca aggaaaaacg ccggaagcac gtgagctaca catgcaagta
     2041 atgccaatag tagaatcact tagccggcaa attttagagt tactggataa tgaacaaaca
     2101 gagacgtacc aaaaaggaaa atacgaaggt cagcggttca atgcaagcaa agtagcatat
     2161 ggtgatttga gaaattttga caaaaagaac ccgccacatg agcaaccttc tttagcggta
     2221 gctgtacgga tcgatgaatc tgggtcaatg atacgggatg atcggatcga agcggcaaaa
     2281 aaagcagcga ttgccattgc cgaattttct aagaaagtcg atatcccatt gttgatttac
     2341 ggagatacag cagaccgttc gtcaagagaa aagacttctt tgttttctta taaagaattt
     2401 gaagacggat ttcaatggtt aaatgaaaaa ttagtcacta tgaaaccaag gcaaaacaat
     2461 cgtgatggtg ctgcacttcg tttagcagca gaaaaattaa acagacaatc cgcaacaacc
     2521 aaactgttgc ttaatattag tgacggtcag ccaaaagcgt tgccggatta tacaggcaaa
     2581 aaagcaaaag aagatatcca gtctgttttg aaagaatatg aacgtcaagg aatcctattt
     2641 gtctccgcag ctattggcca agacaaagaa gaaatcaagt cgatctacgg tgaaagtcgt
     2701 tttgtagata ttactgactt gaatgaattt cccaagcaaa tgattcaact gattgcccgc
     2761 tatctatgat aaaataaagc tcaacgaacg cacttagcag attcgttgag cttttcgttt
     2821 ctagttaccg gtaacaagga tacttctaaa atagaatcgg ttataatcaa gagggaccgt
     2881 taaaggagtg aaacgatatg atacaagaac aaaaatggtg gaaagaagca gtaggctatc
     2941 aaatctatcc tgctagtttc aaagatagca atggcgatgg tcaaggagac atcaatggga
     3001 tccgtgaaaa acttaattat ttgaaagatc ttggtatcgg ctttatctgg atcaatccga
     3061 tctatcaatc tccatttgtc gataatggtt atgacgtaag tgactatcaa gatatagaag
     3121 agagattcgg aacgatggaa gattttgatt tattgctaaa agaagcacat gaattaggga
     3181 tcaaagtgat tatggatctt gtcatcaacc atagttcgga tcagcatcaa tggtttgaag
     3241 aatcgaaaaa atctaaagaa agcccgtatc gcgattatta catttgggtc gacggggtag
     3301 atggcaaaga accgaataat tggacatcga ttttcggcgg ttctgcttgg gagtattctc
     3361 atgaaactgg acagtattat ctgcatgttt ttgcaaaaga acaaccagac ttaaattggg
     3421 aaagcgagaa attgaaagaa gaactattca atatgatccg atggtggttg gataaaggga
     3481 tagatggatt tcgtttagat gcgatttctc atgtaaaaaa agatgaatat tcagtaaaag
     3541 ccacagagaa ccctttctca ccctttcaaa atgtctcagg aatcgaagaa catttgaccg
     3601 atttgaaaca tgtttttgaa gagtacgata tcatgactgt cggagaagca agtggtgtca
     3661 ctgcagaaga aggaccacaa tgggtaggga aagacggtta tttcgatatg atattcgaat
     3721 ttgatcatat ccatatctgg cagcaagaaa aagaagggca attagatgtc cttaaattga
     3781 aacatgcatt aagcgcttgg caaacttcat tggatggtat cggatggaac gctttatata
     3841 tggaaaacca tgatgttcct cgtgccgttt cagtgtttgg agatactcgt cccgattttt
     3901 gggctatgtc tgcaaaagca atcgctatga tgtatttctt tttgcaaggt acgccattta
     3961 tttatcaagg acaggaaatc ggaatgacga atatgccctt tgaatcgatc gatcaagttg
     4021 atgcagtaga ttcgaaaaga ctttataaaa ggctgcttgc ggaaggtaag acaagagaag
     4081 aagcattgga tatcattcgt gaaacaacga gagacaacag caggacaccc atgcaatgga
     4141 cttcggaaca atatgctggt ttttctacac atgaaccttg gctgatcact aatccaaata
     4201 ccaaaacgat caatgtagaa caacaagaat atgaaccaga gtcggtcctg caattctata
     4261 agaacatgat ccgcattaga caaaccaata aaggtctgat atacggttct tataaagaat
     4321 atcttcatga acatccacaa ctttatgtct atgaaagata tttagaagat gaacaatatc
     4381 ttattatggt aaacttaaca gaatcacttg ctgactatga acttccaaaa gaagcagatc
     4441 agtcctggac attactcttg tcaaattcct ctagcggaga atttgaagct aaaggcatac
     4501 tagcacctta tgaagctcgg ttatataaaa caaacaagta aaacttcctc gttaaagttc
     4561 attagttgga ctttgcgagg aagtttttca gattgctctg tcaattactc atttcaataa
     4621 ttcgctctag gaccaccgat atatttagga cgagagcgaa gggctgtcac gtgagcttgt
     4681 ccaagggttt tcaaacgagg tctgacaggt acttggacat gcttgatatg cataccgatt
     4741 gatgtgtcac cgatatcgat accggcttgt ccaactacgt gttccacttc gacaggatca
     4801 ttgaactggt caaaagcagc aacagaacaa gcacctccag catgtagtgc aggaacaaca
     4861 gagacaattt cgaaattttt tgcttctgcc actgttcgtt ctactactaa tgctcggttc
     4921 aaatgttcac aaccttggac agctagcgca atttctttag gatccaacaa ctcttttaac
     4981 gtacggatga tccattgacc aacttccgca ctggaatttt ttccaatatg tcctccaacg
     5041 acttcgcttg tgctgcatcc taaaacaaaa agatcacctt ttttcaagtg tgcctcagcc
     5101 aatatgtcat taactatttc agtcaattgg tcttttaatt ctttttctga caacttcatt
     5161 ttctaaaacc ttctttttca attaatattg cttccgtgct tgaatacgtt gaagacttgc
     5221 agttatagga aaggcaagtc ccattccaat cagattttgg aagatgtttc ctggtataga
     5281 agccactcca gccggccaat catataaaat ccaaccggcg ataccatagc cgatgatcat
     5341 aactaagctt cctaataaaa gccctaatcc ccacatacga gtagaagatt tgctgaaaga
     5401 accagcaaca tatccttgta acccgtggat cactaatgaa aaaactgccc actgcggata
     5461 tcctgaaatc aaatcgatca atagaccact ggaagcacca acaactaatc cacccgttgg
     5521 accataaaga aaagcagcgg tatagatccc ggcctcgcat aatgtcacaa atccattcgt
     5581 agccggtaca gggatcaaaa ttgttaatga aagggcaact gtcaacgcaa tcagcatagc
     5641 atagatcgtt aattgcttag ttttcatttc tcattcctcc tttttgaata ccgccagacc
     5701 agacacttcc ggtatgatcg ttcatcagca cgccattaga aatacaatgg gcaacaaatt
     5761 ttttactttc tgctactgct ttggtaaaat ctgcccctaa cacaagattc gctgttattg
     5821 cagaagaaaa ggcacaaccg gccccgttta ctgttgtagt gtcgattttt ttatgagaaa
     5881 atacctcata atgatcaatt gaatagagaa gatccacagc ttcatctcca gccatccttg
     5941 tgccgccttt gatcacaatg ttttttgttc ctgaagcagt gagttcttta gcgagatgga
     6001 tcatttctgt taacgaagag ggaagagctt gaccagaaag taaagcagct tctgccaaat
     6061 taggcgtaat catcgtaaca agtggaaaaa gttcttcgat gagctgcgaa atatacaatt
     6121 gattgatcac agcttcagtt tctttgaatg ccaaaacagg gtctaaaatg attgggatat
     6181 tttgttttgt ttttatgaag tctcgaacaa ccatgattgc ttcacttgaa ttcaataacc
     6241 caattttgat accatctaat gaagtcattt tatcaatcga aactaactgt cgtttaagca
     6301 attccaaaga tatagattcc agcataaatc gctcattaat atctagtgcc cctatagaag
     6361 tcaaggcgct tagtccgaat agaccaaaat tctcaaaagt ttttaaatct gtttggattc
     6421 ctccaccagc aaatggatca gaaccgccaa ttgtcaagat tcttttcata acattttcct
     6481 ccatgaataa gagtataacg aaattttcaa aaaagaaaaa cagccaattg gcatattttt
     6541 atctcatcca atttaaaaaa acaaaaagaa aagaaagacc aaaatggatc tttctttcct
     6601 taaatagtta ggacttttgt gattttaatt ctttctcgat ttgaagccgt tgcactttca
     6661 ttgtagctgt tcgcgggatt gcatcaaaat cacggatgat agggacgttc aagcgaggaa
     6721 gttcatggac ttgctcccac catcgattcc aatccatttc tttatcagga gctaaagcaa
     6781 taatcggttg tggagaatga tttttatccc ttacaatcac tacttctgcc aaaaaatcta
     6841 acgaatctaa taaaaagtct tcaatagcta atgtactatt gatcgtttcg atcaaatcca
     6901 cttgccgatc tttcaaaaat aggtggccat gcttatccat aaaaccgtaa tctccgctat
     6961 cccaccaatc gccataaaca ttttcctgga accgtgcatc ttccttgtaa taagtcaaag
     7021 cccgtccttt agacagtaat tgtatatgac catctgtgtt ttcaggtagg acattcccaa
     7081 ctgaatctgt aatccgagcg cttgtcatgt cttccagtcc aacgcccata tctcttgcat
     7141 cacttgtttt caaactctct agtgtatgag ccttaagaat cattggtccg cattcacttt
     7201 ggccatatac ttgaagaaat accgcatcct gtgccatcga cgttcgcaaa aatgtcttca
     7261 ttgtctggtt gtttatagca tcaaaagtgg agtgatagta tcggataccc gaaaaagctt
     7321 ctggatgctc cttagcagta aaacgccact gaacaaagtt attcggatgg gtctctagtg
     7381 caattggccg gtgagcttcc aacatatgaa caacttttga actttgtgcg tttgctaaag
     7441 gcatcatagg aaatcccatg gacatcaaag aagagatacc aatattgaat ctggaatgca
     7501 ctggagagat gtgaaaagcg attaatttct tttccgaaat ttttgtgaaa actgtttttt
     7561 gccatttcgt ccgccatccc atagaatgag cagaatgaca aataagttta gggataccag
     7621 ttgtaccaga agtatgggtc atataagaaa tttcattttt gtctaaaaat gattgagaaa
     7681 cagacaaagc aggttgttcc attaaataaa gaataggaat ctgttttgat tttgttccat
     7741 ttgaaatttc tctcactcgc ttttttgtct catcatcaaa taaaatgaaa gggtcttcta
     7801 aacgatcgat aaatacttcc attgttgttg ttggtagatg ataagaagtc atgacaggca
     7861 ctgcaccaag gtaagacaca gaaacagcta gaaggtatgt gtcaaaagcg gaactcttat
     7921 aaataataac tttgtctccg gatttcactc caagatgagc caattgataa gcccgtttca
     7981 acacactttc gcagcatttt ttgtaagttg tttcaagtcc taattctggg aaagctgaaa
     8041 gtggctcatc aaagataatc ggggtctcgg aaaagttagc tgcagcttct tgaaaattcg
     8101 taaataagtt caaaggggaa tacgttatgg tctccatcat tcacactcca ttatcttttg
     8161 ttaagtaata tacaaattca agataatcgt aacataatcc tttatataat aacatagttt
     8221 attgtgaaaa aaagatcata catttgtttt atatggaaga aacccgaacg aatgccgcta
     8281 attcgtgata agaaaaatca accatctttt cccagatatc ttgaaaagaa tgggatgaga
     8341 ggtatcgatt accacataaa taatttaccg cgtcagcatc atctaaatat agttctgcat
     8401 aataacgata tgtttttctg catagttctg gcgatacgtt tttatatact gtaattttgc
     8461 tcaaaatttg gcgaatagtc cgaggagaaa tttgctgatc atgtgaggaa cgaaaaacaa
     8521 aagaattttc gtccgtattt tgtgctgtta acttaaaata gttctccaga aatggcatcg
     8581 cttcttttgg tattggtact ttattcagtc tgttttcttt tctattcaga ttaagaatct
     8641 gcttggtcaa agatacatct ttacgtttaa gttctactac ttcatggatc tttaatccgc
     8701 aatacagaag aatggcagta attgcaaggt tcctcggtct attcttttct tcaaagctag
     8761 cttctctgct tgtttgaaag ccttcaatcg ggataaacaa atgctcaaaa tctttgaaaa
     8821 gttctgcatc gatatatcgc ggagctgctt tggttgtttc cggtaaactt gtacccaaaa
     8881 gagaaatctc ttcttcaatc agtccttttt gatacaaaaa tcgtaaaaaa tgatttaatg
     8941 aatattgctt ccttgaaatc ccgtaatagc tattttcaaa caattgctcc gtttcttggt
     9001 tcgctgtagt ttggaacgaa cgagtatgtc gatagatttt agctaagaaa ttctgataat
     9061 cttgtttttc taaatggata atcagctgat catccacttc ttcagaaaat acttttctca
     9121 aataatcagt aaacagatga aaatcttttg cgtattcata gcgactgcct aatgaaaggg
     9181 aagaacgatt ttcttctaaa aactgttgaa agacggaagg gagcaagtgt gtacgttgct
     9241 ttaacttttc ttgcagttgt tttctagttt tgctgtccat tacaaattcc ctccaatagt
     9301 gttcattttc tatattttac cgcatttcat caaatgaaga tagacagttt gtcttgatct
     9361 taggaagcaa atttttaact aagtactagc taaaagatat gaagtaagaa gatacatttt
     9421 tagttatttt attagtgcag tcattctttt gatcttttaa ttgatttatc ctctttttag
     9481 ctatgtggtt acttcatgag caatgaaatg gatttggttc gttctaatgg caggaggctc
     9541 tttcttttat ttccgaaaaa ttagaaaaca ttttttcaga atcgattggc tctccattta
     9601 ttcaataatg gtttgtctaa cgatattgtt gggataattc ttaaagaagt attagaaata
     9661 gttggtactt cattacttta catgaagatt tattctatgg taggagcaat tatattgaga
     9721 attaatcctt tttta
//
LOCUS       DADVXB010000107         9723 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.109, whole genome shotgun sequence.
ACCESSION   DADVXB010000107 DADVXB010000000
VERSION     DADVXB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.109"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            34..657
                     /locus_tag="KB902_002084"
     CDS             34..657
                     /locus_tag="KB902_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808874.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="KB902_002085"
     CDS             1107..2156
                     /locus_tag="KB902_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6808875.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="KB902_002086"
     CDS             2153..3034
                     /locus_tag="KB902_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6808876.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="KB902_002087"
     CDS             3037..3807
                     /locus_tag="KB902_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6808877.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="KB902_002088"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="KB902_002088"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBB6808878.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="KB902_002089"
     CDS             5118..6281
                     /locus_tag="KB902_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6808879.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="KB902_002090"
     CDS             6398..6808
                     /locus_tag="KB902_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6808880.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="KB902_002091"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="KB902_002091"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6808881.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="KB902_002092"
     CDS             9381..9665
                     /locus_tag="KB902_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808882.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
BASE COUNT         3372 a         1648 c         2087 g         2616 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttc
//
LOCUS       DADVXB010000108         9656 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.110, whole genome shotgun sequence.
ACCESSION   DADVXB010000108 DADVXB010000000
VERSION     DADVXB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.110"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(371..1681)
                     /locus_tag="KB902_002093"
     CDS             complement(371..1681)
                     /locus_tag="KB902_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6808883.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIRD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1721..2989)
                     /locus_tag="KB902_002094"
     CDS             complement(1721..2989)
                     /locus_tag="KB902_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6808884.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     LAKNITGPYELDPGFPMLTASDKPASTLQCTGYGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNAGRILPNADWCDTKCRPSMCRSGRRIYAGTHWLPIVYNRWSHPISFSTRKDLYDG
                     KLVTSILLICIRNHFASRLPTESFKNCIYW"
     gene            complement(2993..3403)
                     /locus_tag="KB902_002095"
     CDS             complement(2993..3403)
                     /locus_tag="KB902_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBB6808885.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHPTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(3400..4323)
                     /locus_tag="KB902_002096"
     CDS             complement(3400..4323)
                     /locus_tag="KB902_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBB6808886.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKLLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTIKFSEHNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(4320..5198)
                     /locus_tag="KB902_002097"
     CDS             complement(4320..5198)
                     /locus_tag="KB902_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBB6808887.1"
                     /translation="MQLNDFLGAPSSRRTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVAALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(5185..6522)
                     /locus_tag="KB902_002098"
     CDS             complement(5185..6522)
                     /locus_tag="KB902_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6808888.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETGRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKTAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSKQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(6525..7628)
                     /locus_tag="KB902_002099"
     CDS             complement(6525..7628)
                     /locus_tag="KB902_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6808889.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(7702..8955)
                     /locus_tag="KB902_002100"
     CDS             complement(7702..8955)
                     /locus_tag="KB902_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6808890.1"
                     /translation="MASDELGDIVTLQIAMLKNSSVRNALKSGVFWDVSEYLKDYKNL
                     SQISEDRIEAASIDGALYGVPIQKDYARAGLVIRKDWLDNLGLDVPTTMDELYEVAKQ
                     FTENDPDGNGVDDTVGFGDRAPSDIRYTSFKLFTSYFGAPNGWAVDDNGKFTPEFDTE
                     EYMKALNFSRDLFENGYLAQDFAVTQKTDQQEQFAQGRTGIYTGMVDIKNLKTMGQGI
                     QDDMELVPVNKISDGEGGGYHVWSEGNGIGGLLAFPKSQVKDEAQLKKLLQFVDDLLE
                     EDVYKLMTGGIEGTHYELNDDGSIEFIDMDLWQQEVQPLSSSRPSEVTFSFKDTDPEK
                     EFSNQLIKENEEFAVMDPSVPLDSPTNNEVGSEIEKIVIDATVQYIMGQLDEDGFKKA
                     VEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(8974..9210)
                     /locus_tag="KB902_002101"
     CDS             complement(8974..9210)
                     /locus_tag="KB902_002101"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808891.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASK"
     gene            complement(9176..>9656)
                     /locus_tag="KB902_002102"
     CDS             complement(9176..>9656)
                     /locus_tag="KB902_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808892.1"
                     /translation="NYRETLLMSWIYGAIGIVLLVDLSFIHNWYLRIALYIAAFIYVL
                     SALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGIYLMIIQTMPGVLT
                     FIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEKIYEKSNARKIRS"
BASE COUNT         2747 a         2110 c         1618 g         3181 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt ttcgatttcg tttttcgaaa tctttcagca
      121 actcatttat cataacttat cgtttgttat ttgtcaagaa cttttttgga gtttttttcg
      181 atagaatcaa gcttcgcaag tggttctttt taacgactta gttatcttat cacgtctaaa
      241 aacatgtgtc aactcttttt tggaattttc ataaaatgtt tcaatgaagc gcgacaacgt
      301 tgtttaatat atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct
      361 tattataatt tcaacgattg tcaaaagtat tgtttgcagc tgtattgcca gtttctatag
      421 ataaatcaca gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg
      481 cagttatttg gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta
      541 aatcaaaagc tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga
      601 tgtgtatgtc tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt
      661 gccaactttc tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc
      721 agtccattat ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga
      781 tattttcgat cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact
      841 gaaaaaaatc gatatcgcga atatatacgt cactaactcc agcactaact tcgctaccaa
      901 tagttacacc gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc
      961 gattgactct tgcaccattg ccatccctgc cagacttaat agcaatacaa tcatcaccac
     1021 aggccaaatc acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg
     1081 tacttggtcc atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag
     1141 tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt
     1201 ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa
     1261 gtcccttttg atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct
     1321 cccaccaatg gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg
     1381 ccgagagaac attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat
     1441 cgatttctgg aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga
     1501 taagatgact cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa
     1561 atacaggtaa gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat
     1621 cttgttgagt gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca
     1681 atacgtttct ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt
     1741 tgaacgattc agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc
     1801 tggtaacaag tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc
     1861 acctgttgta gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc
     1921 acatgcttgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtccggcat
     1981 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     2041 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     2101 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     2161 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     2221 tttgtactaa gctcccatat cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     2281 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctaggcaaa
     2341 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     2401 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     2461 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     2521 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     2581 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     2641 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     2701 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     2761 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     2821 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     2881 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     2941 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     3001 cttttctcat tcttactcga tataaactga atgccccagc tgcgaaataa aaaaatgcaa
     3061 aaggaaacgc aataaactga gtgccaatca acaatatgaa tcctgttata aaatacaaac
     3121 cagtggcagt tgttaagtat tttcctttag cagtcaaaaa caatgctact gctaaaaaag
     3181 caagtgaaat aaacaacaca acggcaaaca gaccagtcat gtcctgtaat aatccaaatg
     3241 tattttctaa agacaaagtt ggatgatcta cagcaagcga ctgataactt tttttaaact
     3301 ctgacgcaga catattactt aaagtaactg ctaacccgcc aaagaaaatc aaagatagac
     3361 tgccaccgac cattcctagc aatagttccc attttctttt catttctgaa ccccctgctt
     3421 ttctaaatgt atccattcag gtcttttgat cgatgtttca taattgttat tatgttcaga
     3481 gaatttgata gtctgttcat ttttcttgtc atcccaatta tcccaaccag ttgggtgaac
     3541 atgcccacct atcttacacg cttcaaataa gacatttgca tacggacgcc acggtcttcc
     3601 taaatagacg tttctagtat caggttctgc agtcaaggta cagctttcaa aacgataccc
     3661 tgttttttga tttttcggcg tagatgctgc tgtgatgtat ccaggatttt tactggctaa
     3721 gctatggata tgacactgat gaaaaacggc atctgcccca ccaaatatga aatccaccgt
     3781 tccttcaatc cagcaatatt cataggtctg acgacaatac tcaggattgg cagaagccgg
     3841 tgtacaaaaa ggagtaccat ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc
     3901 ctgataacca gatagtcgac agttttttaa agatacgcga tctcctgaat tgaataaagc
     3961 aacagcctgt cctacctttt ctcctggacc tgctgtattt tcgatgtgaa gattttctaa
     4021 tacgacattc gatccttcta agaaaaaagt agcacttcgg aaagtcccta actggctacc
     4081 gtcaagatac tcctgttttg caaaacgatt accggagata actactgttc ctgctcccac
     4141 aagtttaaaa ttggataatc tgctttctat atattcatca tatcttcctt cttttactat
     4201 caagagcttt ggatggctat ccggcaggcc tgccaaataa tcgattcctt cttggatagt
     4261 ttcaaaatcc gtcggggtat ctatagcatt ctttccaatt atcagtttgt ctttcatcct
     4321 cataaatgct cccttatgaa ttgtttccaa atgtttctca tttcttgtgt ttccatatga
     4381 ccgcctgtta aagaaaaaga agaaaagttt tctggactac ccattgattg atactttttg
     4441 tccagccctt ttctcagctt cagtacgcct tcgtccaagc acatcgtatc gttttttcca
     4501 actaagctaa gacgagggcg cggagcgatt ttttcttgga ttgctaacgt tgtataagct
     4561 gtcaatagat ttggcacata gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa
     4621 agtgtttcga tgtccacctg tgccgctaga tcaatacaaa ctttgacacg agaatccaat
     4681 gctgccaccc accagcttaa taagcctccc atagaaagac caatcgttgc gagccgttga
     4741 gtatctgtgt cttcccttgt ctccaaataa tcgatcaagc tgatcacatc ataaatacgc
     4801 attccccata acgtttttcc tgttaataaa aattgtttga acaactcgct ttcagaaata
     4861 cctccgcgtt cttcaaatcc ccaagcatca atcgaccaaa cagcatatcc cattcctgtc
     4921 agtacttctg caaaagatgg agaagctaag taaggagcac catggatcaa ttcacttttc
     4981 ccgactgaaa aatctccgcc gtgagaatgc aggtaaagga ccgtcggaaa cggtccttct
     5041 ttttctggat aagcatagag ggctggtact gtttccaatt catttaagta caattgatag
     5101 tattcaagca taaaaccgtt ttgtttttct cggtataatc gttttccact aggggtacgt
     5161 ctgctagatg gagcacctaa aaaatcattc aactgcataa gcaaagtttt tacgaacaac
     5221 cagttcatcc atattttctg attgatttga ttggaatttc tcaatactga tttctttcgt
     5281 attttctaat agaaatgctg gtccctcgtg attttcaatc gacatctggt taaaggaaac
     5341 cttacctgca aagccaatgt aaaatccttg cttgctcatt tcctctatcc ctgtcatcat
     5401 agcagggaca ccgggaactg catcttgggc cattgaaaca tcaatattgt caaatgtgat
     5461 ttcttgtata aactgttctg ctaatccata aataaatcct gcagaagcat ggacattcct
     5521 tgccgtgata ttcgaaaaat ggatccttct gaatgctggt gtccgctcat ctatcggata
     5581 agccgttttt tcccatacgt acggttcttt ccctcgcgga ccacagaaat aataaagatt
     5641 cagtataaat ggacacatca cattatccat gactatattg gatactcgaa tatcttcaac
     5701 gatcccgcct cgacctcgtc tagatttcaa tcgtattcct cgaccagttt cttggaagat
     5761 acaatttgaa atggtaatat tacgaatact accactcatt tcacttccta atacgacacc
     5821 gccatgtcca tggaccatcg tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc
     5881 gtacgtatct tcagtccctg ccttgattgc aatacagtca tctcccacgt caatatggca
     5941 attactaata cgtacatttt tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc
     6001 cgctgggttc aagatcgtca agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat
     6061 cgtccaactt ggtgactgga tcaatttaat atctttcaca gtaattcgat gacagttatg
     6121 gaaactcatc aatttaggac gaggataagc gagattatct ggttcatttc taaaagtatg
     6181 ccaccatttt tttccatttc catctaatgt accgaaacca gtgacagaga tgttctctac
     6241 attttgagca tagatacagg aagcataaac ttttcgatgg actccttccc aacgtgaatg
     6301 aacaacagga taatcttttg gatcgtcaga gaatttcaga accgctcctg cgcttaaatg
     6361 aagttcgaca ttgcttttta aaaataaagc tcctgttaga aattcacctg ctggaacaac
     6421 tacggtcccg cctccgtcac ttgctgcagc atcaatggct tgttgtattg cttcagtatt
     6481 caattcatca attgatgcgc caaatgtcaa aatatcatac atatttataa tgcctccact
     6541 tcaatcaatg cttgcaagaa tgcaccaacg cctttttgat cattacaaat aattggttca
     6601 ctgatgtagt aagcatatga accatctcgc tgatctgctc cgcctaaccc tgctacttga
     6661 cagtttttat tcaagttcag ccagccttct tttgtttcca gaacaaattc atcaagtaat
     6721 ccttgatgtg atttcttcac ttgtggaagc cattcttctt tgttcagcag gcccaaacgt
     6781 attcctttag ccattgcgta aacaaacata ctactgccgg aagcttccag ataatttcct
     6841 ttccgttttg tttctgttgt tacttgatac catgtcccgc tgttttcttc ttgatatgga
     6901 agtaatgcag ccagtgtctt ttctagaatt tctttcagca aagaacaatc tgtttcttca
     6961 tgaagtaatt cataggtatc tgctgcagcc atcaaatacc agccaatcga tcggctccaa
     7021 aaatgatggg atagacctgt ttttggatca gcccatggtt ggaccttctt ttcatcccat
     7081 gcatgaatca gcaaatttgt ttttggatcg aatagatgtt tataactgat ttcaaactgt
     7141 ctcaaaacat cttggtaatc tttttcttca ctaaaattct ggataaattc agcataaaaa
     7201 ggagaaccca tatataagcc atccaaccaa atttgataag gataaatttc tttatgccaa
     7261 aaagctcctt cggatgtgcg tggatggttt gccaactgct gggaaaggag ttctgctgct
     7321 tttttatatt tttcttcgcc tgtttctttg tacaataaaa agaaaagctt tcctgtattt
     7381 acatggtcga tattgtattc ttcaacgctg tagccacgga tcgttccatc ttcttgcacg
     7441 aaatagtcga tattgtcttt tatgaagtca aaataaattt tttcttgggt tcgttcccaa
     7501 agtaattgga accctttaag tacgacgcca tagtcataag accattttcc tttataccac
     7561 ttttcttcat ataagcgagg tgttctttcc atgatacttt ttgctaattt ctttgaccag
     7621 ttttccatta tttgctctcc tttaaaaatt aaaataggat ttgggacaaa taccaagaag
     7681 tatttgtccc aatcgtctat attactgtgc cgctgctttg tatgcttcct cgtactcttg
     7741 tgtgattcga tcgcctcctt gtgctttcca gtcttctaca gcttttttga atccatcttc
     7801 gtcaagctgt cccatgatgt attgcaccgt agcatcaatg acgatttttt caatttctga
     7861 tcctacttca ttgttcgtcg gtgaatccaa tggcacagaa ggatccatta cagcaaattc
     7921 ttcattttct ttgatcaatt gattagagaa ttctttttca gggtctgtat ctttgaaaga
     7981 gaacgtcact tcactaggac gagagcttga taacggttgc acctcttgtt gccaaagatc
     8041 catatcgata aattcgatag aaccatcatc attcaattca taatgcgttc cttcgatacc
     8101 gccagtcatc aatttataca catcttcttc taaaagatca tcaacaaatt gaagtaattt
     8161 cttcaattgt gcttcgtctt ttacttgaga tttgggaaat gctagcaagc cgccaatacc
     8221 atttccttct gaccaaacat gataaccgcc gccttcacca tctgagatct tgtttacagg
     8281 cactaattcc atatcatctt gaataccttg acccatcgtc ttcagattct tgatatccac
     8341 cattccagtg tagattccag ttcttccttg tgcaaattgt tcttgctgat cagtcttttg
     8401 ggtaactgca aagtcttgtg ccaaatagcc attctcaaat agatctcttg aaaaattcaa
     8461 agctttcata tactcttctg tatcaaattc tggagtgaat ttgccattat cgtctacagc
     8521 ccagccattt ggtgctccaa aataagaagt gaacagttta aagctggtat aacgaatatc
     8581 actaggcgca cgatcgccaa aaccaactgt gtcgtccaca ccatttccat caggatcgtt
     8641 ttctgtaaat tgtttagcta cttcataaag ctcatccatg gtagttggaa catctagtcc
     8701 tagattatcc aaccagtctt ttcgaatgac taagccagca cgagcgtagt ctttttgtat
     8761 cggtacgccg tacaaggcac cgtcgatact cgcagcttcg attctatctt cagaaatttg
     8821 acttaaattt ttatagtctt ttaaatattc tgatacatcc cagaatacgc ctgattttaa
     8881 cgcattgcgg acagaagagt ttttcaacat cgcaatttga agtgtaacga tatctcctag
     8941 ttcatcagaa gccaatgcag ttgttaatct ttcttatttt gaagcatcag gaatccagtt
     9001 gaatgtcagt tccgtatcgg ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg
     9061 tgaagcatga tgcaaaatat ttaaccaagt gattttagct tttccatctt ctgtctctga
     9121 agaactgtta cttgaactgc tgccgcatgc ggcaagtgct agaattcctg caaaactaag
     9181 acctaatttt acgagcgttg cttttttcat aaattttctc cttcactgtt ttaataatat
     9241 ttttgttttc ttctgttttt tctgtatatg agttcttcca ttccaaatgg caaaatatag
     9301 aatttgctgt ccacgtgact gcggaaaaga agagactacc accgataaag gttaaaacac
     9361 ctggcattgt ttggatgatc atcagataaa tccctaccat acttaatatc aacactaatg
     9421 agtaatgaag atgtgagaat ccgaataaaa atgccatttt cattttgaaa aaatatcctt
     9481 tccaatcata atgagccatg attgggaaaa tatagagtgc tgagagcaca tatatgaacg
     9541 cagcaatata caaagcgatc ctaagatacc aattgtgtat gaaagaaaga tccacaagta
     9601 aaacaatccc gatggcgcca tatatccagc tcatcagcaa ggtttcacga tagttt
//
LOCUS       DADVXB010000109         9629 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.111, whole genome shotgun sequence.
ACCESSION   DADVXB010000109 DADVXB010000000
VERSION     DADVXB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.111"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            167..1165
                     /locus_tag="KB902_002103"
     CDS             167..1165
                     /locus_tag="KB902_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6808893.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1277..1786
                     /locus_tag="KB902_002104"
     CDS             1277..1786
                     /locus_tag="KB902_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBB6808894.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1816..2475)
                     /locus_tag="KB902_002105"
     CDS             complement(1816..2475)
                     /locus_tag="KB902_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6808895.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2477..3241)
                     /locus_tag="KB902_002106"
     CDS             complement(2477..3241)
                     /locus_tag="KB902_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBB6808896.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3249..3926)
                     /locus_tag="KB902_002107"
     CDS             complement(3249..3926)
                     /locus_tag="KB902_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBB6808897.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3963..5348)
                     /locus_tag="KB902_002108"
     CDS             complement(3963..5348)
                     /locus_tag="KB902_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6808898.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5558..5642)
                     /gene="ffs"
                     /locus_tag="KB902_002109"
     ncRNA           complement(5558..5642)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KB902_002109"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5665..6180)
                     /gene="tadA"
                     /locus_tag="KB902_002110"
     CDS             complement(5665..6180)
                     /gene="tadA"
                     /locus_tag="KB902_002110"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBB6808899.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6287..7144
                     /locus_tag="KB902_002111"
     CDS             6287..7144
                     /locus_tag="KB902_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6808900.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7225..7560)
                     /locus_tag="KB902_002112"
     CDS             complement(7225..7560)
                     /locus_tag="KB902_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808901.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7627..8997)
                     /locus_tag="KB902_002113"
     CDS             complement(7627..8997)
                     /locus_tag="KB902_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBB6808902.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9075..9611)
                     /locus_tag="KB902_002114"
     CDS             complement(9075..9611)
                     /locus_tag="KB902_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6808903.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         2817 a         1989 c         1618 g         3205 t
ORIGIN      
        1 aataataaca taatacctaa cctctcgtaa aaatactaga tttgttttct tttatttttc
       61 atcactagat acattctata acttaccgtt tcgatttcga attcaaacat ttttgagaag
      121 cattctcaat taaattctgc tatagtgtga aaagggagga atttttatgg aaatctatga
      181 cattacaatc atcggtgcag gtcctgtagg gatgtttgcc gctttttacg caggaatgcg
      241 ccaagctaaa acaaaaatca ttgacagtct acctcaactt ggtggtcaat tagcaacttt
      301 gtatcccgaa aaatatattt acgatattcc tgggtatcca gcaataaaag caagtgaatt
      361 aatcgatcaa ttagaaaaac aattaactac ttttaaccat acattccatt taaaagaaga
      421 agttctctcg cttactcgtg aagacgaagt tatcgagatt actacaaata aaggcatcca
      481 ttattccaaa gcagtcattt tagctttagg aaatggttca ttccagccaa gaaaattgaa
      541 tttagataat gctgaatcat ttgaaaacca cggattggat tatttcgtga atgatttgat
      601 gaagtatgct ggaaaaaaag tcgctattgc tggaggtggt gattctgcta tcgattggac
      661 gttgatgtta gagcctattg caagcgaagt ttacttgatt catcgtcgcc cggaatttcg
      721 tgcgcacgaa catagtgtat cacgcttgaa atcttcatct gtcaacttgc ttactcccta
      781 tctcatcgat ggattatcag gcaataatgg ggaactgaca gatatccggt taaaaaaagt
      841 gaaaagtgac gagacgattg atttgatgat tgattctctg atcgtcaatt atggattctc
      901 ttctaattta gaacatcttt cttcttgggg acttgatagt accagaaatg ccattactgt
      961 aaaatcagat atgtctactt ctattccagg cgtttatgca gctggtgaca tctgtaccta
     1021 tgaaggaaaa gtgaaactga ttgctactgg gctcggtgaa gcacctactg cagtgaacaa
     1081 cgctttacac tatattaatc caaaggaacg aactcagcct ggtcacagca caagcttata
     1141 cgataaaaat cttcgtccta gttgattttt tatatctctt tgcatttcaa gttaaacccg
     1201 aaagcagttt cttgcatttt tttcatgttc cgttaacatg aaatagagaa agaaaaaata
     1261 aagggggagc aataatatgg tcgtcaaaac tgagacttta gaagaaaagg caagagaact
     1321 attgaaggaa cgtggcgtaa ctgtagaaga tatcgcacaa cttgtcatgt ttttacaaaa
     1381 agactatatt tctgatttga ctttggcgga ttgtactgaa agtgtcaaca gcgtgctaac
     1441 aaagcgtgaa gtacataacg ccattatcac tggaatccaa ttagatatat tagcagaaaa
     1501 gaaaaaattg atgagtccgt tgcaacatat tatcgaagat gacgaaggcc tttacggtat
     1561 cgatgagatc ctagccttgt caatcgtgaa tgtttacggt acgatcggct ttacgaatta
     1621 tggttatatc gacaaggtga aacctggtat tttaaaagaa ctaaacagcc acgatggcgt
     1681 tcatgtccat accttcttag atgatatcgt cggagcgatc gccgctgctg ctgccagtcg
     1741 attagcacac aaagaaccag aaaaaagaag tcgccttact caataattca acaaaaaaag
     1801 aaagaaaacg tctatttaga cgagttcttt cttttttgtt tgtttcaagc tattttttcc
     1861 taagaaaaga aaaacagcaa aaaataattc taataataca aaaaataaga taaagctatg
     1921 catgaaaaat tcttctggaa gtacattgat gattggatca gtaacgggat cgaataacca
     1981 gtcatcgttg ttgaaaaacg tttcatgaaa aaggataaaa aagcgatcaa atcctatcat
     2041 catgaaaaaa ccgaaaacaa ctggcagtaa catgccgatt tgaaacggac gaatcaaccg
     2101 ccaaagccga tcattctttt gcaaatattt gataaacaaa atactcggga tcaaagtgat
     2161 gaaaaacaca gcataatcca ctaaaaacaa aattttcact tcataaaagt gatgggctcc
     2221 gctagcagaa actgggaaat ctggcaagct gaggatggtt ttgaagggat tattgagata
     2281 attcattagg tgatcaaaat ttttcagtaa cgtctcttga tctaaagaag tataatccaa
     2341 aatttgcaaa tgtccgatat caaatacgta tagtggtcga aagttgatcg tcacaccaac
     2401 tgccagactg atcagtgtca gaaataggct gaacaatcca gcatattcca tccactgcca
     2461 tctcgaattt ttcatattag aagctccatt catccagtga ttgtttcaca taggtagctg
     2521 ggataggcaa cccaggtaca tcttcttctt ttgtaaaacc tgataaaacg agcaaagtat
     2581 ctatattatt gcgtatccca gcttggatat ctgtttcata gttatctcca accatgatta
     2641 cttcttcttt ttgcagccct aatacttcaa cggctttatc cataatgatg gcttctggtt
     2701 ttccgatgta gatcggcggc gtttgggttg ctgtctctac aaaagagatg actgaccctg
     2761 ctccaggaag aaggccgcgt tcagtaggta tattcttatc tgggttcgtt ccaatgaaag
     2821 tagcaccttt ttgaatagca agtgttgctt taactacttt ttcataggtc agataattat
     2881 ctaagcctac cactacatag tcaggagcct cttcttccca tgtaaatccg gcagctaaaa
     2941 tcaagtcaat caatcctgct tctccgataa catagacttt tttccctttt ccatctgctt
     3001 tcataaaatc gattgttgcc aaagtagctg tgtagactgt ctctggagct acatgaatgt
     3061 caaactcatc tgctagacga ttagctactg tttctggtga cttagtcgtg ttattggtaa
     3121 caaacaagaa aggtaatttt cttttttgca attcttccac aaatcgttta ccggccggta
     3181 tgggttgtgt cccacgataa atcgttccgt ctaaatcaat taaatatcct ttatagtcca
     3241 ttcatccact actcttccct ttttctgatc gtaaatgctg tttttgtttt ttctacttgt
     3301 ttaggttgtt cttgtttttt tactttttca gaggtttttg ctgactctgt ttttcgattt
     3361 ttaataaccg gttttttgcg attagatgcg actggtcctt ttttctcatc gatatacgca
     3421 cgattatggt tttttttctt ttttcggcgc tgagttgtct tttctttttt accgccgatt
     3481 ctctcgatga caaaatacgc acaaccaaaa ttgcaatatt cgtaaagata gtcttccaag
     3541 gaatcgattc gctgatctgg atgcgcccgt cgattatccg cttggaaaaa tccttttagg
     3601 cgtagttgtt cataacccca atctcctacg atataatcat atcgggctag tacatcactg
     3661 taacgttctc caagcttttc tgcattaaat ccttcacgat aatcggacac aagccgataa
     3721 tgtctttcac ctatcaaaaa attactgtca tctaacagtg tcactagctc gcctttgact
     3781 ttttctgctt taggctcctc aacgatttct tccaaagcag ctgtcagttc ttcggtgact
     3841 gttgtttcct gttcagctga tgattttttc ttagcaattt ctgttttatg ctcaacgttc
     3901 tgctgttcat tttgttttgc agacatgcgt tcaccaccta tcttttttat tataccttgt
     3961 ttttatttga ttgggtagtg agctttcaag taatctccta ccacacttcg gataaattca
     4021 gggaacaaaa attcattttt tccagcaatc tcaatcgttg gaaaaaatgg aacaaacatc
     4081 aaatgatcta cggtagtaaa agtataattt ttattcagat cgattggctt gttcttccaa
     4141 aagacttgat ggttaataga atcatatgtg attccattat agaccatctg cccaaaaatc
     4201 ttaccgcgaa atcccattcc cttcatagga tagttacgta aaaagttacg atttttttct
     4261 atttctaaaa ctaagcggat cagatcattt ccacccaatg tgacatttaa caagtgcatc
     4321 ggatgcggca acgcagtgtg aagctgatcc tgattgaccc gcccttttgg aatttcagtt
     4381 aaaaacagac cactgtttaa tattgctgct tccgtctttc ctcgttcttt caccgcctca
     4441 aaggctactt ggataaacga atgctcattg aagatatcta gactcagaga aaatggcaaa
     4501 tctgctactt ctttttcttt taataattca tgcccacgtt ctagataact atttatttct
     4561 tgttcatctt ctgtaaaagc tgtcattgtt tcggtaggga tggctttggc tgaatgctta
     4621 aggatttttt tctcttcatc gatggttaaa tggacttcac cgacatactg cccgtacttt
     4681 ccagcggctg ctatttggac atcattgatt acgtgacctt ctctgaataa atgatgggtg
     4741 tgcgatccta aaataacatc aattgctggt atttcttttg caatttggaa atcatcctga
     4801 atcccgagat gactcatcaa aactaaaaca tccacttgtg aacgtaaatc ttcgactaat
     4861 tctggcaaaa tatcataagg attccgtatg tcccagccat tcggattata agtaagcgga
     4921 aatggagcag taaatgcaat tagtccgatt ttcgtctggt gtttcgttgt aatgatttta
     4981 tatggtttcg tccatgccgg tggctggagc gtatttttat cgaataagtt atccaggatg
     5041 atatcaaact cagcatgatc gtataaatga ttcaactctt ctttggaatt tcctacgcct
     5101 tcattgtttc ctatcgtcgc tgcatcataa ccaacttcat tcatcagcaa gatattttcc
     5161 tgtccattcg ttgcttctga caatggatgc caacgatcca caaaatcacc tagatctact
     5221 gcaatcgttg tcgttttttc tttcttttcg ttttctcgtt tacgttgatc caaaaacctt
     5281 ctgatccttg gccaattttc taaatgagaa tgcagatcat tcgtatgtaa aatcactatt
     5341 ttttccatgt accctctcgc ctctctttat ctttatcata ccataggcag ctttttcttc
     5401 cattgaaaca agctctattt cagagttttt cctgccttga agcaaattgt ataagtacaa
     5461 tattcgataa atcagtctgg ctaaaaaatc aggaacattc atttttacag tactataaaa
     5521 ataaaaaaaa cagacccgaa agtctgttgt cgtttcatta taatcagaca catggcggaa
     5581 cctgcttagt gctgcttcct tccagacctg acacgcttca caagcccacc attgtcctag
     5641 cctttcggca aagaatagta taccttattt ttcattcgtt gaccagtctt tttttaattt
     5701 cttttttcgc tggcggagct ttcggaaaaa gtcagtcaaa atcatcccac attcgtcttc
     5761 taaaatgcca ccttctacat atgcttggtg gttaaaccgc tcgtcctcca aaagattcat
     5821 caaggtaccg gctgttccgc cttttggatc atacgcgccg aaataaactt ctgctacacg
     5881 agacaaaatc atcgcgccgc tgcacatagg acaaggctct aaggtaacaa aaagtgcagc
     5941 atcttccaag cgccagcttc ccactttttc acaggcttcc ttgattgcaa gcatttctgc
     6001 atgtgtagta gcatcttgcg tggtttctct aaggttatat cctcttccaa tcacttttcc
     6061 atccaataca accactgctc caatcggaac ttcatgaagc atttctgctt tctttgcttc
     6121 tgccaatgca aggcgcatcc atttttcttt ttctactgca tcaagatttg tatttaccaa
     6181 ttacccttcc ctgcctttgt tttttcttgt tttactttag catatgataa aaaggctgta
     6241 actaactttt ttttctatgg taaaataaat acaagaggtg aacaagatga aaatggataa
     6301 attacttgct ctttacccac aagcacagaa aaaaaactct ccagcatcag aagcggatat
     6361 cctttctttt gcaattgatg atgcttttat ctggatcaaa caagattcat tatctcaaca
     6421 agaaaccagc cttttgaaag cgttattccc tgtaatcaac gatcaaaaaa aacacccatg
     6481 gtatcactat ctttttaaag atgcttcttg tgttcaagaa aaaagctttc gtttgatcca
     6541 gcttcacgtc gaatcaaaag gagaattctt aaaaaaagaa tggcaagata ctattttgga
     6601 attatttcgc tattctgctg atttcttttt ttatacagac acagatgcgc tcttagtcga
     6661 acaaataaac cgtgattatc ttgatgctac tgaaatcaac ggtatttttc tatctttaga
     6721 tgctgatttt gatacgacaa cgtctgtatt cgttggttct ttccattcac ctggcaccga
     6781 cctcgtccct ttgtttgctg aagaaagaaa aattttttta acagagcaaa acaatcttta
     6841 tactcacagc cgtacttttt ctatgcaaga tgtggcttta cattactata caaaagatac
     6901 tgtaaaagat agtaagttga tcaaaagtta catagaactg atcaaacaaa atgaaatgga
     6961 agtgatcatt caagaattat ggaatgaatt aggcaatgtc agctctgctg caaaaacact
     7021 gtttcttcat cgtaatactc taaaatatcg aatcgaaaaa tttcaagaac agtctggttt
     7081 caatctaaaa aaagccaacg atttactgtt ttgctatctt ttattgcttc atgaacataa
     7141 ttaaagatag attaaagggg ttgtgacaat aattttgtca caacccctta tttcgaatga
     7201 atagtgttca aaagctagtt tctcttacat cattttttca acaaaatgca ttagccggtc
     7261 ttttacatct tcggttgaat ctttgattga atcaccataa acagagattt tcttttttcc
     7321 tgatttgatt tttgctaaca ttcccatcaa agaatccaag tcactatctg aaagaccatc
     7381 tacgatttct agtaattttt catttccatc aaatttgtca tagacgaatt tttttacttt
     7441 cgtccgagta gtcatatgat ggatcttttc cattactttt cccgatacaa cgactgctgt
     7501 cgctacactg gcagcggctg ctacgcttaa tccgattgtt acttttgttg atgttttcat
     7561 aagtatcagc tcctttttat ctatctccat catagcatag acaaaaaaat aaacgaacta
     7621 atccactcag tgaaatctca atcctttagg gaaaaagttc tttactgttc cttttacttg
     7681 tttcccaaat ccgacaggta tcttatctaa tactagcaaa acccatcctt gattcccatc
     7741 acgttgaaat gtttctcctg ctgtgtaaga ttgccattcc ttttgagtga tcggcaagca
     7801 aggtatattc tctatctttt ttgtagcaag cgctaatgca tagctaggtt caaatcgatt
     7861 ctttttgaaa tctcctaaat gcaaacctgt acgtacgact tttaaaccat cgagagaagg
     7921 ggctaactca ggaacttccc aaagatggtc gttgaacact aaaagtcttc cagtagcttc
     7981 ataatgaaaa tcatttgaaa actccgtcca gagtttttcc tgctcttttg tcatttgcac
     8041 tttacttttt tttcgtgtct tcttttcttt atgcatctga ttttgtccat gaaaagtcag
     8101 ctttgcaaca aaatgtcctt caccctgatc tttatgaggc catatacgta ttgttttttc
     8161 caaaccagct acgcttcccc attcagaacg tcctgaacta acggattgag tcaaaggaat
     8221 ctcctcaatc gttactggat aattttctac aagccagcta atgatctctt cattttcttc
     8281 tggtgcaaac gtacaagtcg aataaatcag ttgtccttta ttttttagca tttttattgc
     8341 tgaagacaaa atctcttgct gacgtttttg acagtatagc ggagattctt ctgtccactc
     8401 ttttattgca tttggatctt ttcggaacat tccttctcct gaacaaggag catcaaccac
     8461 gatccgatca aaaaagcccg aaaaatgagg gacaagttct gcgggtgcat gatttgtcac
     8521 tattgcgttc gaaactcccc atcgttctat attttctgat aaaatcttcg cacgtttcgg
     8581 aaagatctca ttcgtcacta ataacccttt ccccttcatt tgagcagcta attgggttga
     8641 tttaccaccg ggagccgcac acaaatccaa aactttttca ccgggttttg ctgcagcagc
     8701 tgttccaacg atcattgcac ttggttcttg gctatattca tacccagctt gatggaggaa
     8761 agactttcca ttgacagtgc caagaaatcc ctcattgctg tagggagcgg gttgtaattc
     8821 ttcgctatgg taagtttgga ccatgtccaa tcctgccggt tttagtggat tccaccgaaa
     8881 tccttttttc acgcttcctt gttcaagcgc agaaaaaaaa tcggatgctt cttcgcctaa
     8941 aagaagacga tattttttga taaattgctg tggtaacgtt gtcgcttcct ccttcattcc
     9001 aatgtttcgt tagacatttt acaatctttt ttacgaaaaa taaaggtggc tgatctactt
     9061 tttcatgttg ctgcctaagg tgactgttcc tttaagatat tttccaagta ttcatccgtc
     9121 acctcgtttt tatcccaaac agcgttcatc atttcaagaa aatcttgaga agaatcatct
     9181 gagcgcaaac ttcccaatgc attaagccat accaattcaa gcgacttttc ttctttgatc
     9241 ttcgtgtgac ctttgacata tgagaaaaat ggccgcttaa atagcgaatc catgtctaaa
     9301 tcagattttg caatgatttc acgaatactt tcatggatag aaaaaaaatc tttcaataag
     9361 tagacaatgc ttaaaacatc atcggaactg cattcagcta agtagttttc aaaataaaca
     9421 gtgatttctt ctaatatctt ctcttttaac ccgctgattg atttgaaatg tgtataaatc
     9481 gggtatgtag aacaaccgca gaactctgct aactctcttg cagtaattga cttcattcca
     9541 tattcttcca cgtataccat acttttgaac agcaaatatt ctttactata atttgttact
     9601 ctccccatca ttcttacctc cgtctcttt
//
LOCUS       DADVXB010000110         9587 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.112, whole genome shotgun sequence.
ACCESSION   DADVXB010000110 DADVXB010000000
VERSION     DADVXB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.112"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            209..538
                     /locus_tag="KB902_002115"
     CDS             209..538
                     /locus_tag="KB902_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808904.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(825..1310)
                     /gene="vanZ"
                     /locus_tag="KB902_002116"
     CDS             complement(825..1310)
                     /gene="vanZ"
                     /locus_tag="KB902_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBB6808905.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(1463..2374)
                     /gene="vanY"
                     /locus_tag="KB902_002117"
     CDS             complement(1463..2374)
                     /gene="vanY"
                     /locus_tag="KB902_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBB6808906.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(2802..3410)
                     /locus_tag="KB902_002118"
     CDS             complement(2802..3410)
                     /locus_tag="KB902_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBB6808907.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(3416..4447)
                     /gene="vanA"
                     /locus_tag="KB902_002119"
     CDS             complement(3416..4447)
                     /gene="vanA"
                     /locus_tag="KB902_002119"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBB6808908.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(4440..5408)
                     /locus_tag="KB902_002120"
     CDS             complement(4440..5408)
                     /locus_tag="KB902_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBB6808909.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            5740..7031
                     /locus_tag="KB902_002121"
                     /pseudo
     CDS             5740..7031
                     /locus_tag="KB902_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7129..8283)
                     /locus_tag="KB902_002122"
     CDS             complement(7129..8283)
                     /locus_tag="KB902_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6808910.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(8261..8956)
                     /gene="vanR"
                     /locus_tag="KB902_002123"
     CDS             complement(8261..8956)
                     /gene="vanR"
                     /locus_tag="KB902_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBB6808911.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(9170..>9587)
                     /locus_tag="KB902_002124"
     CDS             complement(9170..>9587)
                     /locus_tag="KB902_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6808912.1"
                     /translation="QEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLD
                     LSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMN
                     YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
BASE COUNT         2798 a         2024 c         1680 g         3085 t
ORIGIN      
        1 caattttcaa aggagtttta tttgattagg aaattatgta gaataataat atgtttttaa
       61 cttggaatca aaaacgcact tgcaagtaag tttacttcaa tacatgaaat tgcttataat
      121 agtgtattgg aattaaggta gattgacaaa agagtgatca aataggtata cttcattcaa
      181 ataatcgttt gaatgtgagg tgagatgaat gaaaaaagtt tgccaagtga ctgtcgtaca
      241 taaagaaaaa gtaaatggaa taaaaaataa attggatcaa aaagattttt caaacttact
      301 tgtgttaggg aaatgtttca gcgatttttc tagaattaaa attttctatg ctttagaaac
      361 ctataaggaa atgtgcgtct gtgatttagc agaaatactt actgctagtg tcgctacaac
      421 gtcacaccat ttacgttttt taaaaaaaca tggaatggca aaatcacgtc aagatggaaa
      481 agtagtttat tactctttag cgaatgaaga catcctttcc gctattcgtg ttttttaaag
      541 ttatcagaaa atctatctat gaaatcttag tttgggggta ccgtcaggaa aatgcggatt
      601 tacaacgtta aggaaattta ttaaagagac caattcctca gcactaaaat tgataattgg
      661 gctttctttg ttactatagt gttaggtaag ctttttactt tatcaccggt tttcccctca
      721 cttcacacct acgggcgagt ttccccacat cccgttttcc atctaatcca attcattcaa
      781 tatctttatg tgtatgaaag atcagattgc ttgatttaga catcttacac gtaatttatt
      841 cttaaatggg tacggtaaac gagcaataat acgagcaaaa gtatacctac aaaaataata
      901 actctgtcta attttttttg attcatatgc ttattgctta aaccatataa tttcagtcca
      961 agaaagcctc caacagtatt tgtaattaca tctgttatgt ctgtcgctcc aatagcgaag
     1021 ataaattgaa ttatttcaaa agtaagactt aaaaccagta caaaagcaaa cttaggtaaa
     1081 aatccgattt ctttaaaatt gacattcaaa agcaagccaa atggaataaa gattataaca
     1141 ttatctatca tctctctgaa attcccagta gcagtaaatg gagtcaagtt aagacttctt
     1201 tgatgataat taaatactga taaaatattg tattgtaatt tgaataacac taaccagatt
     1261 agtgtcacta aatataaagc tagcaatcct ctagataata tttttcccaa tataatttcc
     1321 tctaattctt ttgtttaagt tgtatcatta gtatagcaat gtcctagtta acgtgggttt
     1381 taaattaaaa agctaacgtt accccaaaag tgctagtaca ataatgctgt tcattaattt
     1441 cgttggtttc attccgccat ccttacctcc ttgaattagt atgtgttgat ccgggaaaca
     1501 ctgtcacaat tacaccgtct atattgtttc ctgatatctc ataacgaaga ttagtcggca
     1561 catgaatggt ggtattttta gtaacaggat aataaaagat ctcatatttt tccccattta
     1621 cactaacaga aatggttttt tcttctttta ggtaatccat atattcctcg agaacgaaat
     1681 tcttttcttt cataatcgca ctatgtggta aaccaacata gcgaatatgc catagttcat
     1741 attgaattcc tgttaactct gttttgtcct ctggataacg taaaatgaac ccgtatttcc
     1801 aagcattttc ttctatccac tttccttcag gggctcgttc cattttcgtc aagcttgatc
     1861 ctacatctag tgataaacct gaattatgct cactataacc tgctggtaag gcatactcag
     1921 cccccatttc ttggtaaagc acactttgct catcaaagtc tcgatagcca ctattaataa
     1981 taaaatgact aacgccaccc tttacagcat cattgaccat ctctgaaaat ttttgtgcta
     2041 tttcttttga catataaata ttactatcaa gcaacccgta tccatttatt aattcgtcat
     2101 gtttagataa attcacgata tctgacttca cactttcttg gcgaacagga tatttactat
     2161 tgattaatag cagatttcct tgataaacct gttcttctgt aattgttttc tcttgggtat
     2221 tttcagaagt cccactattt tctaaatgtt ctttgggatt ttgatcataa ttttgaaatt
     2281 cgactttttc ctgagaaaac agtgcttcat taacgtagtc ataacctaag tatattaaga
     2341 ataacaataa caataaaaaa aacaacttct tcattttcag tctcctcctt aactatatag
     2401 ttggaagtat gaaatatttc tagaatcttc cccttaaacg gcacaatctc gtttgagatt
     2461 gtgccgtttt gccccgtaaa ttacagtcaa ttatttcgcc ctactggatt tactattatc
     2521 accaatgtag atgaattttc ataagtgata cccatgctga atttaacgag gctgaactgc
     2581 ctgttgacaa tgggcggtgt gaaataccac ccctctatgc gatcagtctt attatcaggc
     2641 tatcttgccg cagcgcacgc agataatgac cgcaatatcg ctctgcctta catcttcaat
     2701 actatctact atatataaat tccctaagaa ccagttacat acgtcgggtt tcctgccgaa
     2761 agagttagct tatatagttt gtccgtgcaa cggttaaaag tttatttaac ggggaaatca
     2821 aaatagctat tggggtatgg ttcgtctctt aatacatagt gccaccattc gaggctatat
     2881 gcttcaaacc cactgttttc catgatggag cgcaaacgtc tgcgattttg cgcttcattg
     2941 catgatattc catttgccgc atgatgagag cgttcatcca taaaatcaaa tcggctcccc
     3001 attggtacaa gctcacccgt gtctaatcga taaagcgtaa gatcaatggc actgccgcgg
     3061 ctatggcttg attttgaagc cacgtatcct tttgaaatca tctcagttcg gtcaatattg
     3121 ggataataac tttcctttgt caggttattt tccggctgtg cagcccattg cataaaacag
     3181 tttacagcac gattaggacg gtaaccgtcc catagaagca atccgtaccc ttgggtagca
     3241 gccagttctt ttgccttcaa aagcgattca gccaactcgt atgtccctac aatgcgattt
     3301 acttcataac cgtcaaccgg ttttccggtg aaattatccc aagtggcata tttagcgtcc
     3361 caacgaacac cgtgtactat ttcatctaaa aaagtaaatc ctatttccat gcttatcacc
     3421 cctttaacgc taatacgatc aagcggtcaa tcagttcggg aagtgcaata cctgcagcgg
     3481 ccatcatacg gggataacga ctgtatgacg tgaaaccggg cagagtattg acttcgttca
     3541 gtacaatgcg gccgttatct tgtaaaaaca tatccacacg ggctagacct ctacagccga
     3601 gcgctttata tatttttttt gccgtttcct gtatccgtcc tcgctcctct gctgaaaggt
     3661 ctgcgggaac ggttataact gcgttttcag agcctttttc cggctcgact tcctgatgaa
     3721 tacgaaagat tccgtactgc agcctgattt ggtccacctc gccaacagct aacgcggcac
     3781 tgtttcccaa taccgcacaa ccgacctcac agcccgaaac agcctgctca attaagattt
     3841 tgctgtcata ttgtcttgcc gattcaattg cgtagtccaa ttcgtccgcg ctattgactt
     3901 ttttcacacc gaaggatgag cctgaacgcg ccggcttaac aaaaacagga taggtaaacg
     3961 tagctgccac cggcctatca tctttattaa taacccaaaa ggcgggagta gctatcccag
     4021 catttttcgc aacgatgtat gtcaacgatt tgtccataca aattgctgag ctttgaatat
     4081 cgcagcctac aaaagggata ccggacaatt caaacagacc ttgtatggat ccatcttcac
     4141 ctgacttgcc atgcaaagct gaaaatgcta catcaacatg gttgatttca tattcatggt
     4201 tctttttaac aagtaatccg tgcatttttt tatccggcga gagtacagct gaatagcaat
     4261 tgtcgttttc ccattccgcg caaggttttt cgcacatttt ccatacacca gatttcgtaa
     4321 ttccaatgta taacggctcg tatttttctt tattaatgtt agcggctatc tctattgcag
     4381 attttaccga tacgtcatgc tcctctgagc aacccccaaa cagtattgca acttttattc
     4441 tattcatgct cctgtctcct ttcaaaatcc aaacagtttt taatggtttt ttcaacggta
     4501 tcacgcaacg cttgctcggt ataataggcc gtatgcggtg tgattatcac gttaggcatt
     4561 ctttgaagtt taagtaaaaa ttgattatca attggttttt gggtgcaatc agagtagaaa
     4621 aactcttcct ctccttccaa tacatccaat gcggcaccgc ccagtttccc gttttctaat
     4681 gctttaacca actcataggt atctacaagt ggaccgcgcc cagtattgat aagaaatgct
     4741 ccttgcttca ttctctgtat ttgttcgtgg ctgataatat agtgcgtatc cgtattgagc
     4801 ggcacatgaa gcgtaacgat atcgctattt tgcagcaact catcaaacgg tacatagttt
     4861 acctctatac ttcggctgcg actataagcc aacactttac atccaaatcc tcgcagccgc
     4921 tcaataaccg ctttgcctat ctggcccgtt cccaccacac caactgtcat gtcgctgagt
     4981 accttgccac ggtcgctgtc caacctgaaa tcatgttttt ccacagagcg cacaatcgat
     5041 tttacgttgc gtactgccat aagaattagc atcatagtat aatcggcaac gctatccggc
     5101 gagtacgcca cattgtcgac agtgatgccc attctcttag cagcagttgt atctatatga
     5161 ttgcagccga tgcttcgggt agaaatatat ttcacaccgg ctctcttcag cgcaagaaga
     5221 atagaggcgg aaatctctga tttatgtccc acactgatac attgattgaa aggcgcggat
     5281 ttggcgttgg attccgacac gttggcgtta attatcgttg ccataacgcc aaagcgaggc
     5341 gaaagagcat ggaatgcatc tgcctcatcc tgctcacatc cataaacagt aatgccgatg
     5401 ttattcataa ttaagaccaa ccctttctgt gaaaggcacc aaataaaacg gggatgccaa
     5461 tggtaatctt gtcaaatctt tctctgaaga acgaaaacgg ctcgttctta cggtattaag
     5521 tctaccgtgt aagaacgagc cgtttcttaa tattaaattg ttaatttcct aagaaaaagt
     5581 aaagataacc ttgagatttt cctaaaaaat tatggctcta tactttttga tgttggtgga
     5641 tgacaccagc atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta
     5701 gaattaattt ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc
     5761 aaagaaacat tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa
     5821 gaaaaataca aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa
     5881 gaatgcatcc actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc
     5941 gtccggttgt taatgaacga tgtttctgaa taccgtacct acctcgaatt gaaaaagcaa
     6001 cgcttcaaat gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa
     6061 cattgtttca tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaatacct
     6121 caatgacaga gatcgccgct cagaaaaatc tatcggtctc ttctgtttac cgtattatga
     6181 agcgatttta tcgtccgttg aatccttttc ggacaccgtt acctaaggta ctttgttttg
     6241 atgaattcaa atcagttcgg ggtgtttcag gtgctatgag tttcatcatg atggatggac
     6301 aaacacagcg cttattggac attgtcgaga accgacaact gcctttttta aaacgttatt
     6361 ttagtcattt ttcacgagaa attcgtgaag cggtcgaatg gatcgtgatt gatatgtacg
     6421 ctccttatgt atcgctcgtt aaaaagctgt ttccaaaagc acagctgatt attgaccggt
     6481 ttcacatcgt ccaacatatt ggtcgtacct ttcgcaatca tcgaatcaaa gaaacgaacc
     6541 aactattaaa aagcaaagaa caaaaacact atcaattagg taagcaatta aaaagatact
     6601 ggaaacttct tcaaaaagat gaacgcaagc ttgattatac tcgacgcctt tggcgacctg
     6661 gcttcaaagc tcatttaaca gagaccgata ttgtggatcg cttactgaaa gggagccctg
     6721 ctttgcgtgt aggctatcag ttatatcaag actttcttta cgctgtaaag gaacgagact
     6781 acgtatcgtt tgaagaacta cttaccaata atatcatgct tcccgaaggc tatcagacga
     6841 ccttgagaac gttccagaaa tttctgccac aaatcaaaaa tgctttacaa caaagttatt
     6901 caaatggccc acttgaatgt ctgaacaacc atatcaaagt gttaaaacga aatgcatatg
     6961 gctttcgtag cttttataat ttcaaattgc gcatcatgat tcgtcatggc aacgcattga
     7021 ttttcaacta aaaaagatca agaggaactg atccacttga tctccaatta ttctaagatt
     7081 tctctttacc aacatcattt gacaaagagc caaaattata tacatctctt aggacctcct
     7141 tttatcaacc aagtctggca tcgctggaag ctctacccta aacgtcgtat agttatcatt
     7201 gctttccgcg taaatctgcc ctccatgctg aacaataatt tcttttgcaa tcgccaatcc
     7261 aagtcccgcg ccacccgtat cggaagaacg agcattgtcc agcctataga acttttcaaa
     7321 tatggcagct agcttatctt ttgggatgct tccagtgttc ttgaattcga ttgacaccac
     7381 atccccggag aggcccgcgg taatgtcaat gatgctgtta tcctcactgt atgcagcggc
     7441 gtttttcaaa atgttgttaa agactctcgc gagtttatca gggtcgccgg acacggtcag
     7501 atcctcgggg gcgtgaataa ccgcctgttt tccatgtgcg gaaagctgag gataaaattc
     7561 atcggtcatc tgcaccagca tatagtatag gtctatgtgc gtttttgtta gcgttatcgt
     7621 ttgtaggtta taccgtgtaa tctcaaaaaa ctcgtcgatt agctgttcga gtcgatacgc
     7681 tttgtccaac gtgatatgca catactttgc cttttgatct accggcatgt ctggagcctc
     7741 gtcaagcagg ctcaaataac cgataatgga tgtaaggggc gttttaatat cgtgcgccaa
     7801 gtacataaca acgtcatttt ttctttgttc ggccagcttt gcatcctgct ctcgcttttc
     7861 cagagtccgt tttaatgtgt tgagcttttg ttccataaca tccatttccg cagaaagctc
     7921 aatttgttta tcttcgttct gaataagtac atcaatgccg gtatttatct cgtcaaagta
     7981 ttttgcgaat tttgaaagca tgacgcgaca tagaataaga atactaatga caatcgccac
     8041 ataaataaag atatctatat tgttccgtat ggaatattga tataatttca tcgcgtccag
     8101 gtgatttaag tcatatttgt tttccaaaat acttaagatc caatccccaa gtttccctcg
     8161 gatcattgaa cgaatataca acacgaatac aattgctacc acaacaattg caacgatata
     8221 catgtaaagt tttcgttcta gtttggaata gtcgtttttt ttatttttca attttataac
     8281 caacccccca taccgttttt atatatttcg gattatcaat ggtgtcgttc attttttcgc
     8341 gcaaatgccg gatatgcacg gtgatggtgt tgttgctctt gctgaaatat tcgtcgcccc
     8401 atatctcatg aaatagcagc tcggagctaa ccacattccc cttgttttca cagaggattc
     8461 gcagtattga aaactcggtg ggagtaaggg ataactgctt ctcgttcaga taacactcat
     8521 gggtgttaac attaatgaca aggccggagt ggacgataac attttcgttc tgctccttta
     8581 ctccactgaa ttttttgtat cggcgcaact gggcctttac ccgagcaatt aactccagtg
     8641 ggcgaaaggg cttcgttata taatcatccg cgccgattgt taaccctgta attttatcta
     8701 cctctgtatc tttcccggtc agcatgataa tcggataggt gtgcttgtcc cttatttttt
     8761 gacagatagt aaggccgctt gtgccgggaa gcatgatgtc caatatggca aggtcaatct
     8821 cagacttgtc tatacattcc aatgcttctt tggcggtata gtatttgaaa accgtataat
     8881 tctcgttttt taagtataat tcaaccaaat cggcaatttc atgttcatca tccacaataa
     8941 gtattttatc gctcatagtt atcacccttt cacataagtt tgcccttaat aatttatcag
     9001 attatagggc cgaatttata agcatttaca taataaatga ctaagaattt cttaagatga
     9061 tgattctttt tttatcaaag ggcttttcgg catcgctagg aggctgttaa tattttatag
     9121 tttccttttc ttctttaaaa atattgccca ttagcggaat acagaatggc taattattca
     9181 cttctgataa tttcctgtat aatgaagccc tagatacatt agtaatttca caaatttgat
     9241 ttacagtcat atttccttct ttatatagct ttaccgcata attcattcct gcgtgatttt
     9301 tatgatactt ctttaatcga cctttaaact ttccttcttt cttagccaat tcaatccctt
     9361 cacgttgtct catccgaata agatctcgct ctaattggtt aacaccagcc attacagtaa
     9421 ttaagaattg gctgtatgga ttatcttctg ataaatcaag ccatgtatct tttagtgatt
     9481 ttaaacttgc ctttttatct cgtatgttat cgattaattc aaatagatct tgtgtactac
     9541 gagtgattcg agttaagtct gtaacataaa tgatgtcatc ttcctgt
//
LOCUS       DADVXB010000111         9559 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.113, whole genome shotgun sequence.
ACCESSION   DADVXB010000111 DADVXB010000000
VERSION     DADVXB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.113"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            120..2048
                     /locus_tag="KB902_002125"
     CDS             120..2048
                     /locus_tag="KB902_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6808913.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELGNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            2186..2641
                     /locus_tag="KB902_002126"
     CDS             2186..2641
                     /locus_tag="KB902_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBB6808914.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            3111..3380
                     /locus_tag="KB902_002127"
     CDS             3111..3380
                     /locus_tag="KB902_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808915.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            3780..4034
                     /locus_tag="KB902_002128"
     CDS             3780..4034
                     /locus_tag="KB902_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBB6808916.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(4123..5169)
                     /gene="holA"
                     /locus_tag="KB902_002129"
     CDS             complement(4123..5169)
                     /gene="holA"
                     /locus_tag="KB902_002129"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBB6808917.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(5207..7480)
                     /locus_tag="KB902_002130"
     CDS             complement(5207..7480)
                     /locus_tag="KB902_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBB6808918.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(7473..8012)
                     /locus_tag="KB902_002131"
     CDS             complement(7473..8012)
                     /locus_tag="KB902_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBB6808919.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(8148..8366)
                     /locus_tag="KB902_002132"
     CDS             complement(8148..8366)
                     /locus_tag="KB902_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBB6808920.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(8363..8608)
                     /locus_tag="KB902_002133"
     CDS             complement(8363..8608)
                     /locus_tag="KB902_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6808921.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(8724..9452)
                     /locus_tag="KB902_002134"
     CDS             complement(8724..9452)
                     /locus_tag="KB902_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBB6808922.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         2957 a         1861 c         1664 g         3077 t
ORIGIN      
        1 aaaaacaaca tcaagcttaa tcaccaaatg ataaccatta tcgttctcat ttagctgtta
       61 ttattatcaa ttacattttt attatgctat ccttgttttg acaaggaggt ctaataacga
      121 tgactaatca gaaaaaagct tttgcagcaa caatcggctg ccttttattt atgatcttcg
      181 gttttatctt cgaccgattc tctcttacca tcaccccact tttttatatc agtgccatta
      241 tcatcggtgg atataaacaa acatcggaag gcttgaaaga attggggaat gatcggacac
      301 tgaatgtgga tttattgatg gctttagctg ctattggtgc ctgtttgatc ggtaattact
      361 ttgaaggagc aatgttgaca ttcatctttt gtttaagcgg tgcattagag gaatacacaa
      421 ctaataaaag tcaaaaagaa attactgctt tgatgaatct tcaaccacaa aaagcccaat
      481 tattaaaaga aaatggacaa atgcaagaag tagatgtttc tcaactaaag gtggataact
      541 tggtatttgt cgctaaagga gcagctgttc cgatagatgg ctttttagaa agcacacagg
      601 caacgatcga tgagtctgca ttaagcggtg aatctgtgcc tgtagaaaaa tatttaggcg
      661 atgagatgta tgcaggaacg ctgaatcaag gaaatcccat cacgattcga gtaacaaaaa
      721 cgagttccga aactgtcttt gctaagatta tccaattagt agaagaagcg cagaatacgc
      781 caactcaaac agcttcattt atcgaacgaa tcgaaaataa ttatgtaaaa ttgattttgc
      841 ttgctgttcc tctaatgatc cttctccccc actttttcct aggttggagt tgggatgaaa
      901 gcttttatcg aggaatggta ttattagttg tggcttctcc ttgtgcgctt gtcgcatctg
      961 ctacaccagc ttctctagct gctctttcaa attctgcaaa aaatgggatt ttaatcaaag
     1021 gcggtatcca tttagaaaag ctttctgaat taaaagcgat tgcctttgat aaaacaggaa
     1081 cgctcactaa aggaaaacca gttgtaactg acagcttttt ctttgatgaa aaggatttgg
     1141 cacaacaact tcttgttgct atggaacaaa aaacgacgca tccacttgct catgcgattt
     1201 tgcaatattt cgattgcaca atacctgaag aaatccaata cttaccaata gaagaaatta
     1261 ctggttttgg attacaaact acctatttag gtgcgcaatg gaaagttggc aagcacgcat
     1321 atgatcctga gacgatgata atcagcaaag agattgcgga aatgatcgaa cgtttggaaa
     1381 atcaaggcaa aaccgtgatt tatctttcta aagatcagca gttaattgct gttttaggtc
     1441 tgctagatat tccaaaagca aatacccaac aagtaatttc ctactttaaa tcccaaaaca
     1501 tccatacaag tatgataacc ggcgaccatt ctggcacagc aaaggccatt gctgaacaag
     1561 tagggattga acattactat gcaagctgta ctccggaaga aaaaacacaa ctagtcaaaa
     1621 aagagaatga actttaccaa gtaaatgcga tggttggtga tggagtcaat gatgcgcctg
     1681 ctttagcagc cgcttcttta ggtgtcgcta tggggcaagg gacagatgcc gctatggata
     1741 tcgcagacat cgtcttaatg aaaagcgact taaataaatt tgtctacagt catcggctat
     1801 ctttaaaaat gcggcggatc atcaaacaaa atattatttt ttcgattctt gttattctct
     1861 tgttgattgc ttctaacttc ctgcaatttt taaatctacc tcttggagtt gtaggacacg
     1921 aaggaagcac aatattggtt attctgaatg gcttgcgttt actaagacct ttacctgatc
     1981 tttctgattc ttcaaaaaaa tgtaagtctt gtccactata caaagcgcgg ctgtcttctg
     2041 tcaaataagc aaagtgtttt tttatgattt tgtttatttt atgaaaaaaa cagcttatga
     2101 ataggtcttg aaggatgaat tcctactttt gtaactttct aaaaacatgt tatgattgtt
     2161 tcgaagaaag tgaggaatat atttcatgga aagttggctt tttttaggaa ttattttact
     2221 tgtagcaatt ttagctaaaa atcaaagtct gatgatagcg gcagcttttg ttttgattat
     2281 gaagctcata ccagcctccc gttccttttt cccttggctt caaggcaaag gaatcaatat
     2341 tggggtgacg atcatcacag cggctattct aatccctatc gcaacaggag aaatcggtct
     2401 acgtgatcta ttagaagcct ttaaatcccc tattggctgg gtagctgttt tttgcggtgg
     2461 gctagtggct gtcttatctt ccaagggtgt aggattgatt gcttctgatc cacaaatcac
     2521 tgttgcactt gttttcggca cgattttagg tgttgtcttc ttaagaggaa tcgccgccgg
     2581 accggtcatt gcttctggta tcacttactg tatcttacaa gtatttgctt taggaaaata
     2641 gaacaaattt tgtctatttt aggagattct taacaccccc aatttactga tccgtgatat
     2701 actgacaacg aggtgataca atgttcgaaa aattaaagta tttcatagga acaatcggct
     2761 ggtttcttct agcggtactt ttgattctgg gcttagctta tctattattt cctgatttga
     2821 tacaaaatgt gtttgatact gctttttgat tgacctatta aaacgatata ggggatgctc
     2881 ctgcgatgca ggggcttttt ttaatcaatg ttttgtaata atttaggccg tgccaatgag
     2941 acttcctata gaattcgatg ctcttttttc tttttggctc ttctgctctt ttttgttata
     3001 ctagattaca gtggacaaaa gaaagaatga tcgcatccac ttcaacgaat atcaaaatgg
     3061 aagaattagt gcctgttttc aggttacttt gaaaagaaag gaagacgctt gtggaaactt
     3121 ttgaaggtct tttaattgat acgtacgttt tacaagaaca gccaatgatg ctgactggga
     3181 tcaacttgca gcttgaggac cgtgtgatca atggcctgct taaagatcgc tatttggcaa
     3241 aatatatctt acgtttgccc ctaaataaat atgtgctgga agtaagtggc aaatggaacc
     3301 gtcggaacca gttggtcata aaaaaaatgt tgataaaaaa tatcgatgaa tacattaaaa
     3361 taatcggtac accagaatag cctttactga tcaaaggata ctggttataa aataactgca
     3421 gtttcttaat agaaaaacaa agaacaacag ggaatcgtat cccttttcaa aaaaaacttt
     3481 gcaaacggtt ctctttgtta tataataact tagtaccaaa cattcccatt caaactttgt
     3541 ttaaatagat aaataaaaat ctagtttggt ttgacgctat tgcctcccac aatagcgtct
     3601 ttttgatttt tttcagcttg tactatccgt ttttactgaa aaaaaatcct aataaaagac
     3661 tgttaaggaa aaaaacttgt catgttcata ttgcaaagca cgctgccttt aggtataata
     3721 atgaatgttg aattatgcgg taacacgcgt aagaacttaa gttatcggag gtgaaactaa
     3781 tgccaaacat tgaatctgca atcaaacgtg ttcgtacaag cgaaaacgct aatgtgaaaa
     3841 attcatctca aacaagcgct atgcgtactg caatcaaaaa atttgaagat gctgtagctt
     3901 caggtgctga caacgtagat gcgttatata aagaagctgt taaagctatt gatatggctg
     3961 aatcaaaagg tctaatccac aaaaacaaag ctaaccgcga caaatctcgt ttaagcaaaa
     4021 aaatcgctaa ataaaagaat cggcttcggc cgattttttt atttgtcaaa aaaaggacaa
     4081 aaacaaacga ccttcccgca tgctttgccc tcgtctttct tcttatcgat ttcttaacaa
     4141 ctgccctgtg cgcaaaacga atagttgaaa acttaattct ttttcgattt gtcccgtttt
     4201 gatttgataa tccatctcaa ctaattgatc aaacaactgt accagcaaat gttcatcgaa
     4261 tttttttact tcctgcatgg caagttttac acgatatgga tggattttca atgtttcagc
     4321 aatatttgcc tgctgataac caatctttac aagaaatttt gtctgtaaaa ataaacgtaa
     4381 ttgagaaagc aaaatcgcat taattttgat tgtttcttcc ccttgcataa ctaaatcttc
     4441 gtataaacgc aaagcttgtt ccgtcttccc ttttaaaata tattgggtca tgtcaaaaat
     4501 attatgttct aacgttttag gaactaattc ttctacttct cttaccgtga tttgctgttg
     4561 attttgtcca taaaggacca atttctgtaa ctctctcatc attttggata aatctaagtc
     4621 ggtcaacctc aagaataaat caattgcact tcgttccatt ttgattgagg aattctctaa
     4681 ggtattcatc agatattgac gtacttcttt ttcattcaac tgttggacat tgatgataat
     4741 tgctgttttt ttcaattgtt tcgttacttt tttccgttca tccaactttt catatggcgc
     4801 aaagaatact aatacagtcg attctaatgg ttctttcaaa taagccgtca ataaatcagt
     4861 attttgttcg attccattgt ttactttttc acctgttaaa aaataaggat tctctacgaa
     4921 tactaaccgt tgatctccga aaaacggcaa cgtctctgct tcagctacta cctcatctaa
     4981 acttgcattt tccatgtcaa aacttaaaaa atttaagtca tcttcgccct ctaattggat
     5041 ttttttgaca atttctgtcc gaacttgatc ttggagaaac ttttctgttc ctaaaatcaa
     5101 gtaacaagat gcaagttttt ctttacgtat tttttgtaac tctgcttgta tactcaaatt
     5161 actcaccact ttcaaaaatt atcctaccat gagcagatga gaattactag tctatcattg
     5221 tttccactag cccatgagga tgaaaaactg gatgccagcg ataggtgatc attccttgtt
     5281 gatccgttcg ccatgttttt atctgatttt cttctagtgt ctccaatact tcgctgtgcg
     5341 ggtgaccata acgattattt acgccgcagg atataatccc atgttttgct tcaatatggg
     5401 aaagaaaatc tgtgttactt gacgtacggc taccgtgatg acctaatttg actacatcgg
     5461 ctttcagatt aggataaatc aaaagcaatt gtttttccat tgcttgattc aaatctccta
     5521 aaaataaaaa gcgcctattg ttatattcca tccatagacc aatcgaatct tcatttcttc
     5581 cctctccctt ttcaaaagga gtcaatacat aaagatcata ataaccgctg atcctgtccc
     5641 catgtttgat ttcaatgatc tcagtaccat ttttttgagc ttcagataaa tgcctttgta
     5701 atggctcatt tcgtccagcg ccccaaccga tataaatttt tttgatagta aaatgctgag
     5761 ataacgtggg taattctccc acatgatccg tatcgtcgtg tgtcaagatg agtttatcga
     5821 ttacacttat cccctgacct tttagatatg gaacgatatt tctttcagca ggaggacgta
     5881 tcataccttg cgcccacttt tctctttcaa agtgtaactg acctccagta tcgatcaaaa
     5941 tcgtttcttt tcgaaaagga ctttgcaaaa agatactgtc tccttgaccg acatcgataa
     6001 aagcgatcgt tgaagaaaag cgtaaaaatg gcaaagtcaa aaaaataaaa gaaaaaagac
     6061 caacataaaa caagtgtttc acaggttgtt ctttcaacct atccatacaa atcagtaatc
     6121 cgaaaatata catcccagat agcacaaggg gcaaacgtcc tataatgaga gacgaccctg
     6181 aagaaaaatc gattattcgc tcaaataaga ttaatccctc ttctatcagc aaaagtaaag
     6241 tttccggcag ccagcgattg aagagtgtga gaaataacac accaggaaga aaaagaaact
     6301 tgaataccgg tgcaatcagt aatgtaaaaa gactacctaa aataggccac tcataaaaat
     6361 gccatacaat caacggcatc gtgatcatag taaacaggac gtgagaggcc gtttttttca
     6421 accaatctcc atcaaaagaa atcaggataa acaaaaaact catgaaaaaa ctaagctgtc
     6481 cacccgcatg aaaaagaaat cgaggatcaa atagtaaaag aagccaaaag acaactgcaa
     6541 ataagtccat ggtggaataa tgcttattca gcaatttgac tagcaatcgc aataaaaaca
     6601 gcaaactagc acgcaaaaca gaaatagaac ttcctgcaat agaaacataa cagatagtta
     6661 gtagactcaa cggaataata ctgacgtgta gtggccatcc gatacgtcga aataaataat
     6721 acagccaccc taaataaaat tggatgtgta gacccgatag actgaacaga tgcagcaaac
     6781 cactctccct aaaaatttct tctggttctc tgaatcctgc atctttatag ccccataata
     6841 aagaattaat atatacactt gttttttgcg gaaattcaga ttggacaaag gagataaaag
     6901 atcctctttt tctctgaagc cagtttcgcc agtgattttg catggtgatc tgttcaatct
     6961 tttgaatttg gaaccgtcca gaaattctat ggttcctgaa gtaagcttct tggtcaaaat
     7021 tataaagatt ccgctttttt gctggagaga tgaactcgcc ttcagcagtc aattctattc
     7081 cctttcctcg gaagttaagc catgttttca attctgcttc tgtgtttact tgataagaaa
     7141 gctggagctt ttgtttattc tctgataacc ttccttccat tgtcaaaaaa ttaccatttg
     7201 cacgaatcgt atctgtaaat acagtaattt gcgcagatgt tgttttttcc tctaaaaatg
     7261 aatactcttg tagcctataa gaaatggata ccgttatgct acacaaaata cacaagtacg
     7321 cgataaaacg tccttctttt agcgaaaacc ataaaaaaat tccggcaaga agcaaacgat
     7381 aaccccaatt gtcagtgtaa tacaacaaac agataatcat cgacgtaatt gccggaaaaa
     7441 tcaaccgatt tcgaacatgc ctttctaaaa cgctagacat gttttcctgt taattcattt
     7501 tgaagttttg aaaaatgctg tgagtctaaa gcaacttggt gtacagatac acctaattgt
     7561 tcgatcaacg cttgggcata aggatcattt cgatagtcat ggagataatt gatccctttc
     7621 acaccagctt gcaacaaagc ctttgtacag gccaaacatg gaaaatgtgt gacatagatt
     7681 tctgaacctt ccgtcgggat accaagtttt gcacactgta ggagtgcatt catctctgca
     7741 tggatcgttc gcaagcagtg tccatccacg acgtaacacc cttcatctat gcagtggaca
     7801 tctccactga ctgctccatt atagccgcca gcaatgatcc ttttttctcg aacgagtgtc
     7861 gctcctactt ctaaacgtgt acacgtacta cgtaaagata acagtactgc ctgagccata
     7921 aagtactggt cccaaggaat gcgttcatta tgtgacttat cagtaacttt ttctttattc
     7981 gtatcgcatg cttttgaaga tttttctaac atgttttata ttcctccgtt ttttcaagtt
     8041 gattaaaaag tactcattgc ttaaacaaaa tattctttaa atataacgaa tcatcctgtc
     8101 tgacaaaaga tcctaccctt cactgccgaa atgaagtccg tcatccatta gcccattata
     8161 aaaattcttc gaatccattt gttcaagaaa ttccgtataa aaatcgatac ttcacaatca
     8221 tggcgttttg ctacttctgt gagaacagag atatattctt tgatcaactt gttattccga
     8281 tatttttgtt ttgtctcatc gactgctggt ggcgtgataa agaaagcatg atcagaacta
     8341 tagtcttttt tcagctgaac tatcatccac tgcagatttt ttggtacgtt tctttagaaa
     8401 gttgtttatg ctctgctaga tcattcgtcc caatgagaat aaatacttta tctgctgtat
     8461 agctaagtac atctttggca aagcgttctc gtagagcttg actgttattg ccgctgacag
     8521 ccgtattcat aatatgaatc ccagatattt tattttggag atagacattc agcattggtt
     8581 tttttaatgt ttctttgcga acaatcaagc tatttcctat ccaaaaatac tacctcctcg
     8641 tcctgccaag ctcttagaat tggattattc ttagtatcca ttagcgtcca tttattgctc
     8701 gtgccagtcg attttgaatc attctattta attgtaacga agttttttag tttttcaact
     8761 gtcttttcac cgataccaga aatctcctgc aggtcttcca ctttctggaa ggatccgttt
     8821 tcttctctaa atcgaatgat ttcttgcgct ttgactgatc cgatcccagg aatctgctga
     8881 agttctgatg gagtggctgt attgatattt attttgggag gctcggaatc tgctgtaggc
     8941 tgttttcctt ccgaggatgc caactgatca agatgttctg gcagctcttc acctacagca
     9001 gggatatata ggacttgctg atcttctatc ttcgcagaaa agttgattcg atcgctatcc
     9061 gcttcttcta ataatccacc tgcacgcttt agtacatcat agacccgttc ttctgaagaa
     9121 aaggaataga taccaggctc cttcacactt cctttgatat cggtgtacat gacctttgga
     9181 cgagcatcct cttctacatc gtttccttca gctgatggat cttctccact ggaactaaac
     9241 gaagaaagta tttcttttgc agcagtctct tctgtttctc tataaaatag caaatttgat
     9301 aataaaaaac cacttgcgat acaaaagata agaactatca tagacatcca aatgatcaat
     9361 ttgggtgaag ctagtatttt cttgctgatt ttttctatca ttgttctttt ttcaaagaat
     9421 gaccagtaaa aatcattcat tactcctttc atttaaaatt gaagaaacag tgagctctgg
     9481 caaaatcgtc ccttcaacat ctaattacgt caattttttc ttttgttttt atttttatcg
     9541 tgaagatttt tgacgaaaa
//
LOCUS       DADVXB010000112         9390 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.114, whole genome shotgun sequence.
ACCESSION   DADVXB010000112 DADVXB010000000
VERSION     DADVXB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.114"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            58..717
                     /locus_tag="KB902_002135"
     CDS             58..717
                     /locus_tag="KB902_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6808923.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLKNMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            802..1707
                     /locus_tag="KB902_002136"
     CDS             802..1707
                     /locus_tag="KB902_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6808924.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1709..2341)
                     /locus_tag="KB902_002137"
     CDS             complement(1709..2341)
                     /locus_tag="KB902_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6808925.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    2492..2617
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2661..3185
                     /gene="infC"
                     /locus_tag="KB902_002138"
     CDS             2661..3185
                     /gene="infC"
                     /locus_tag="KB902_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBB6808926.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            3257..3457
                     /gene="rpmI"
                     /locus_tag="KB902_002139"
     CDS             3257..3457
                     /gene="rpmI"
                     /locus_tag="KB902_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBB6808927.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            3510..3869
                     /gene="rplT"
                     /locus_tag="KB902_002140"
     CDS             3510..3869
                     /gene="rplT"
                     /locus_tag="KB902_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBB6808928.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            4121..5458
                     /locus_tag="KB902_002141"
     CDS             4121..5458
                     /locus_tag="KB902_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBB6808929.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            5506..7635
                     /locus_tag="KB902_002142"
     CDS             5506..7635
                     /locus_tag="KB902_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBB6808930.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            7610..8299
                     /locus_tag="KB902_002143"
     CDS             7610..8299
                     /locus_tag="KB902_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808931.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(8707..9387)
                     /locus_tag="KB902_002144"
                     /pseudo
     CDS             complement(8707..9387)
                     /locus_tag="KB902_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015695319.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
BASE COUNT         2991 a         1685 c         2006 g         2708 t
ORIGIN      
        1 tatttaaaaa ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg
       61 agcgtgatcg ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg
      121 gctgaacact ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc
      181 ttattttatg caaaccccga acagtatgct tttttgctgc aaatttattt tttgaataaa
      241 cgttttgcaa gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt
      301 tatgaagatt cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacggaa
      361 gttcgtgtgt atgatgaact gctgaaaaac atgatggaag aactgcccta tgctgcccat
      421 aaaaaacatc cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt
      481 atcgaaaaac gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat
      541 tacaaagaat tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa
      601 atccaaatcg atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc
      661 ttgaaaatga tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt
      721 acagttgctc aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa
      781 caaatgtcag gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt
      841 tggatcaatg tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc
      901 attagtgacg agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac
      961 gattcttttg atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat
     1021 aatcattatg aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt
     1081 accacgccga ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca
     1141 gacatgagtg tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt
     1201 cctttaatcg aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa
     1261 acaacgaaca agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt
     1321 acaggaacaa aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc
     1381 aagttgtcag aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagct
     1441 gttgaaatga cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat
     1501 ttgctgaata acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg
     1561 accgttccaa ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat
     1621 tccgttttcg gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt
     1681 attgcactgt ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg
     1741 cgatcacaag tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag
     1801 cgattgctgt gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt
     1861 tcgaaccggt caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt
     1921 cgctgtcttc taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg
     1981 aagccatcga agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat
     2041 tcgtacctgt taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact
     2101 ccagattgga aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa
     2161 ctgttttttg catcgtaagt ttttggatat gactctctct taataccata tttttggcat
     2221 cgagatagct ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta
     2281 aataaaactc tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca
     2341 tgtgggttca cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt
     2401 ctgctaatct aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa
     2461 gattagtttt tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc
     2521 cttagttgat aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc
     2581 gcgggttctg taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct
     2641 ctcataatat ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc
     2701 gtgcacgaga gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag
     2761 cagaagcatt gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg
     2821 cgaaaccacc agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga
     2881 aagaccgcga agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc
     2941 ctacgatcga cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa
     3001 agggcgataa agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa
     3061 ttggtcaaaa agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac
     3121 aaaaagcgaa aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta
     3181 agtaatttga atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg
     3241 aggaggaaat atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa
     3301 acgtactggt aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg
     3361 caaaacaaaa aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt
     3421 caaacgtatt cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga
     3481 agatttattt ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc
     3541 gtaaacgtcg taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt
     3601 tatttaaaac agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc
     3661 gtcaaaagaa acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta
     3721 tgaatggctt gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca
     3781 accgtaaaat gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg
     3841 accaagcaaa agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa
     3901 cgaaaagtta tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac
     3961 aataacgtat aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta
     4021 tggtcaccct ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt
     4081 agtttgctta tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg
     4141 tattttgtta gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt
     4201 gatggtcggc tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac
     4261 gttttcacca aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta
     4321 tacgacgggg ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt
     4381 tttcgggcgt gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga
     4441 acttggaggg gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat
     4501 attcatgtcg atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat
     4561 cttgatgtca ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat
     4621 ggctggaatc tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt
     4681 caatccagcg gctgaaagct atacttataa tgactatttc caaattggta tgattgggat
     4741 gattgtaagc ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg
     4801 ctatgcaatg gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt
     4861 agccgtatta ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt
     4921 tattctagca ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga
     4981 aatctgtcgt cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt
     5041 tggtttcttg atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt
     5101 ttcagctatt tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc
     5161 tatattgaca ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc
     5221 tattttagct gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt
     5281 atttgcaatc acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg
     5341 gggattaggt tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg
     5401 ttggatcatc ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta
     5461 aacaaaacgt cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg
     5521 cgaatgggaa ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg
     5581 cacgaaatca tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc
     5641 gcaggtgtcg ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat
     5701 gttgtgtttg ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta
     5761 gcaaaagtcg gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga
     5821 caaactagat tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca
     5881 ttcttacctg tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa
     5941 agagaaagag cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca
     6001 gaacgagttg tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac
     6061 atcacaaaat tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt
     6121 ttaccaaaaa tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc
     6181 aatgtttctt tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa
     6241 aaacgacctg ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg
     6301 tacttgagag cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg
     6361 gtcattaaaa atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat
     6421 atctcttcat tagatgttcg ggttctaggt gtggcgggcg gttcgatggt acgggctaat
     6481 cagtcaggaa tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca
     6541 gtatttacgg agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa
     6601 ggagaccctg ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca
     6661 aatacatgtg cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat
     6721 gtcccatctg cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa
     6781 gacatcgcag aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa
     6841 ttggcagaca agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc
     6901 gctgcctcat tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa
     6961 aacgccgaag tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa
     7021 cgtatcatcc cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat
     7081 aaagcgattg aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca
     7141 cagacttcaa aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta
     7201 accaaggaga tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat
     7261 aaaaatgaag tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat
     7321 cgttcaaaaa atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa
     7381 cgtggacatg cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa
     7441 ctttgggaag atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc
     7501 tgcttaggag caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg
     7561 atggatctgg aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat
     7621 atcaaacaaa cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat
     7681 ttggggattc taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca
     7741 gaaaattctt atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa
     7801 aaagtaccct tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc
     7861 ctgtgaatca gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg
     7921 gattcgattg atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc
     7981 taaagaaaca gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc
     8041 tgttaaggga atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac
     8101 acatcaatca aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat
     8161 gaatcaaagc gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga
     8221 aattcgtagc caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta
     8281 tgatttagat tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg
     8341 aataaacgat gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga
     8401 gaagctgttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     8461 ttggaaaacg gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca
     8521 taagaagcta tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac
     8581 ctctcaataa acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa
     8641 atatgaggaa ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa
     8701 aacctcttat ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat
     8761 cacgtattct tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc
     8821 atcaaagtta tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc
     8881 ccagtctaat tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata
     8941 actttctagc caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa
     9001 atcagtatcc aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttg
     9061 ttctagtatt ttttctagtt tagcttgatc ttgcttggtc attttcgcac tgcattcttg
     9121 caggatcggt ttttccaact tttcccgcgt ataacgggct aatgaagcag atcggatatc
     9181 gatttttgaa acataagtgc cggactgtgg aatggttttt acaagctctt gattgcgcag
     9241 ttggatcagt gcttctcaaa tcggtgtacg cccgatagct agttgttctt ctaacacttt
     9301 atcggagatt ttacttccag gtgctaactc ggaataaatg atttgtttac gtatagattc
     9361 ataagcttgc tgttgcaaat tattgataac
//
LOCUS       DADVXB010000113         9348 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.115, whole genome shotgun sequence.
ACCESSION   DADVXB010000113 DADVXB010000000
VERSION     DADVXB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.115"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            22..669
                     /locus_tag="KB902_002145"
     CDS             22..669
                     /locus_tag="KB902_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6808932.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            753..1697
                     /locus_tag="KB902_002146"
     CDS             753..1697
                     /locus_tag="KB902_002146"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBB6808933.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1832..3283
                     /locus_tag="KB902_002147"
     CDS             1832..3283
                     /locus_tag="KB902_002147"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBB6808934.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3304..4140
                     /locus_tag="KB902_002148"
     CDS             3304..4140
                     /locus_tag="KB902_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6808935.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4140..4799
                     /locus_tag="KB902_002149"
     CDS             4140..4799
                     /locus_tag="KB902_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6808936.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            4925..5614
                     /locus_tag="KB902_002150"
     CDS             4925..5614
                     /locus_tag="KB902_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808937.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5620..6576
                     /locus_tag="KB902_002151"
     CDS             5620..6576
                     /locus_tag="KB902_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBB6808938.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6620..7132
                     /locus_tag="KB902_002152"
     CDS             6620..7132
                     /locus_tag="KB902_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808939.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7388..7936)
                     /locus_tag="KB902_002153"
     CDS             complement(7388..7936)
                     /locus_tag="KB902_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6808940.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8025..9206)
                     /locus_tag="KB902_002154"
     CDS             complement(8025..9206)
                     /locus_tag="KB902_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBB6808941.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
BASE COUNT         3104 a         1710 c         1880 g         2654 t
ORIGIN      
        1 ataacaaagg ggatcgaatc aatgaaaaaa actgttattt atactagttt atttgcagct
       61 ttgtttttag ctgcttgtca atcaaatacc aatcaaggca catctgggaa tacgtcttcc
      121 agtagcgaac agcgctcttc acaggtatcg gactcctcaa caaaagcaag cacatcttcg
      181 tctagccaga caaaaagttc tagtgaagca agtactcagt cagatatcaa agtgtctgca
      241 gctcgtgcga tcgaattgtt ccaagataaa tacccagata ctgcaattac tagtttggaa
      301 ttagatagtg attggggatc ttacttctac aagatagaag gtgtcgatga tcaaaaagaa
      361 tacgaagcaa gaattgatgc tcaaaatgaa aaaatggaga cagagaatcc agaaactcta
      421 gatcgagatg aacaaaatgg tcaaaagaaa aaagaagatg gtctggatgt tgataaattg
      481 atcacgattg aggaagcagc aaaaatcgcc gtcgacaaag taggaagcgg tacggcaaca
      541 gattgggatt tggataaaga tttaggtact acttattggg aagtcaaagt aaaagacggc
      601 aatcaaagta catcagtcaa gatcaatagc caaacaggcg aagtactgtc aactgaacaa
      661 gatgattaag aatttcttcg gaaaacaaga gttgattttt cttttagtca tgatacacta
      721 gacaaaataa cttgtttgaa ggagcgattt acttgagttt agaaacgacc tttgccaatc
      781 atatctttgc caatcctttg atgaatgcat ctggtgtcca ctgcatgact acccaggaat
      841 tagatgaact ggctcattca gaagcaggag catttatcac taagagctgt acgatcaatg
      901 aacgaaaagg aaatcccgaa ccacgctatt ttgatgttcc tttagggagt atcaattcta
      961 tgggacttcc aaacttaggt ttttcttatt atctagagta tgctcttgcg tatgaaaaag
     1021 tgcaggaaaa ccaaaatcaa ccgttatttt tttccattgc cgggatgagt gtccaggaaa
     1081 acttggaaat gcttgagaaa atagaaaaaa gtgggtttaa tgggatcact gaattaaatt
     1141 tatcttgtcc caatgtgcct ggaaaaccac aactagctta cgattttgag gccacttatg
     1201 aaacactgaa agaagtattc agcatctttt ctaagccgct aggaatcaaa ttgcctcctt
     1261 attttgattt tgctcatttt gatcagatgg ctgatatctt gaatcagttt ccattgacct
     1321 atgtcaatgc tatcaacagt gtgggcaatg gtttgtatat cgatacagaa caagaagcag
     1381 tagtcatcaa accaaaagaa gggttcggcg gcattggcgg agagtatatc aagccgactg
     1441 ctttggcgaa tgttcgcgct ttttatacac gtttgaaacc agaaatccaa atcattggta
     1501 caggtgggat tcggacagga caagatgcat ttgaacatct gctatgtggc gcaagcatgt
     1561 tacagattgg tacagagctt cataaagaag ggccggaaat tttttctaga atcataaaag
     1621 aattaacgca gattatgtca gaaaaaggat atacgtcaat tgacgaattt aaaggcaaat
     1681 tacgcaccat ttcatagcaa agagacgaag gtcatgattg atcttcgtct ttttttataa
     1741 aaaacactcg tctgttcatt cctgtgcaag cgtactcatt gtatgttaga cgaacttgtg
     1801 ggaaaataac agaggcaaaa aggaggataa tatgaatgat gcaacagaat tagcaaaaga
     1861 gcttaaagaa aaagaattta gttttcaaga actagttacg gatatacaga aaaaaataaa
     1921 gaagcaaaat catgaattga atgcgtttgt cgcgcttgaa ccattcgaga gtaattccca
     1981 cgagctattg attccccagt cagaaaaagg gccattggct ggtatcccat ttcctttaaa
     2041 aatgctcggt caagaaaaaa agggatggct agctacttca ggatctcgtt tatttgaaac
     2101 acaccgagct tctcatacat ctaattatgt gcggcaagca gaagcgatag gtctagttcc
     2161 ttttggacaa accaatgcgc cagagtttgg tttcaaaaat attacagacc cagtcatcta
     2221 tggcccagca agaaaccctt ggaaccttga atgtacaccg ggcggatcaa gtggaggagc
     2281 tgctgctgca gtttcatcag gaatcgttcc tttagctggt gctagtgatg gcggtggttc
     2341 tattagaata cccgcttcgt tttgcggatt gattgggctg aaaccttcgc gagggacgat
     2401 gccagttggt ccatatgctt ggagaggatg gcaaggagct gctattgatt tcggcttgac
     2461 agtttctatg agagacacgg aggctttatt ttatgggatg agaagtatcc attccggtgc
     2521 gccatatcaa gtatcgccag ttgagtggca aacacatcca agaaaaaaac ggttgaagat
     2581 agctttttgt gttgattcac cgatccactc acagattagt gaagaggcag tacttgctgt
     2641 aaaaaaagct gtagatttcc ttggaaaaga agggcatgat ttgacagaga ttccttaccc
     2701 actagatggt cgtaaactga tcacgtctta ttatcagatg aatggcgcag aaacagcagc
     2761 aatgatccgc tcgattgaaa caggcatcca gcgagctgtc agaaaagaag aacttgaacc
     2821 catttcttgg actttgttcc aatatggtca gaagctctct gccgctactt acatcgattc
     2881 tctgcatgta tgggatgaag cagcaattgt catggaaaac ctacatcaag aatacgatct
     2941 attcctttca ccaacgactg catttaccgc ccctaaaatc agcgaagatt tgcaaagtga
     3001 tgcgataaga gcacagatgg aacacatcag tgattgttct gaagtagaag gtttagacgt
     3061 tgtttcttcc atgtttgagg agagcttgaa gatcacacct tatacacagt tggctaatct
     3121 gactggacaa ccagcaatca gcttgcctac tcatttgaca aaagaaaaca tgcctctagg
     3181 aatccaattt atggctgcca gaggaagaga agatttgcta tttcaaatcg gctatctatt
     3241 tgaagcaaat catcagttcc atttaccaaa tccatggaaa tagcagaaac aaggagaaga
     3301 agaatgaaga aaaaaagatt gtttgctcta ataactagtg ccttttttat tttaagcgct
     3361 tgcggtacag ctgccgctaa tcaggaagat aacagctgga gtaatgtaga aaaaaagaaa
     3421 gaattagtag tagcgacttc tggcacactg tttcccgcat cttattataa tgatcaaaat
     3481 gaattagttg gttatgatgt agatttggca aaagaggtgg ctaaacggtt aaatgtcaaa
     3541 atctccttta aagaatacaa cgtggatgga caaatcactt ctgtttcaaa aagagaatca
     3601 gattttgctg cgaacgattt tggtatcaca aaagaaagag aaaaaaaatt ctccctttca
     3661 gagactttca aatattcatt tgacagtatg atcgtacgaa aaaaagatga ttcaggaatc
     3721 cactcacttg aagatcttaa agggaaaaaa gcagctggcg aacccaatac tagctatatg
     3781 cgtttagcgg aaaaacacgg agctaaatta gtcacatatg acaatgccac gaatgatcag
     3841 tatttaagcg atgtagcaaa tggtcgaaca gatgttattc taaatgatta ttatctgcag
     3901 aaaatggccg tatctgcttt accagatatc cctgtaaaaa tactggagaa cgtttatttc
     3961 aatgaaaacg aaagtggttt tttattgaaa gaaggaaatg atgctctgaa aaagaaaatc
     4021 gatggcgtat taaaagagat gaaagaagat gggacgacaa agaaaatatc tgaaaaatat
     4081 tttcaaactg atgtttcagt caaaccgaaa gaaacgatgg ctgagtcggt gagtgagtga
     4141 tgtactttcc tctaattgat ttttccctca tgtggacttc acttcctttc gtactgcaag
     4201 gcttggtata cacattaggg attggcttcg tgtcgtttct tttaggaaat ttggtagggt
     4261 tgcttttgac agttttaggt cttttggatt ggctgcctct gaatgtattt attcgttttt
     4321 atttatcgtt ctttagaggc attcccgcac tagtcctgct gtttctgtta tatttcgggt
     4381 taccttatca attaagtgcc ttaacggctt cagtcatctg ctttacgatt accagcagtg
     4441 catttattgg tgaaatctat cgaggatcac tagcaggcgt ttcttcaggt cagtgggacg
     4501 ctggtttagc ttctggtttt tctttctttg gggtattgaa atatatcgtt ttgccgcaag
     4561 cttttcgaat ctcagtaccg gcactcagta acgtagctat ggatctagtg aaaggtactt
     4621 cgttagcagc aacaatcaca gtgccagaaa tatttcaaaa agcaaagatc ataggcggtc
     4681 ggacattcga ttatttttct ctctatattt tagttgcact gatttattgg gtcatttgta
     4741 tcgggatcga aaaagtgcaa cagtatttag aaaaacgttc tatccatcag tcaatctgaa
     4801 aaatagaaat ggtgctagcg tggctggcac catttctatt ttttgtttct tgtatattct
     4861 gcctagtatt ttaaaaccat ttcatgtaaa atgtaaatcg aaaatatgtt cggaggtaga
     4921 aaacatgaag accccgctaa ccatcgaaat agaatcctcg ttataccaat attgcatcga
     4981 gcaaggcggc ttggttgtag aagaagtcac gatgcctgat gaccaaggaa ttgtagatac
     5041 gcttagctgc ttgacaaaat ttgatggaag ccgagaatgg cgatgctatg agctgaaagt
     5101 gacaaaagca gattttcgct ctacagccaa actgtcattt gttggacatt ataattattt
     5161 tgttttacca agtaaactat atgaagaagt aaaaactgaa atccctacag gaataggtgt
     5221 tttagtgtat cgtccgtaca cggttgaaga ggagatgcct gcctctggta catttctgat
     5281 tgcgaaaaaa gcagcaaaga aagagcttgc tgtaccggaa gaagctttga caaaccgctt
     5341 catggcttct ttattcaggg aagtaagaaa agcaaagcaa atggagcgag gcgtaaaata
     5401 ttttccaaaa gatcaattgt acaaagaatt gaaaagacgt tcagaaaatc aagatccatt
     5461 ttctaacgaa cgatattatg aacggttttt agaggaaata gctagtcagg caatcaatga
     5521 gttgcaagaa gaagttatcg cgcttcagca tgattatgaa tatttgaggc aacaacagca
     5581 gatccgtcgg ttgcctacag agccattgga gtgaaaaata tgtactatcc ttatttaaga
     5641 ggaaaacaat ttgacctatt agcattaaaa gaagcactgt cgcgaggatt gctctccaat
     5701 aaaatccaac cagtgatcga accagtacgt gattccgcta cgcttaaaaa tgtgatcgaa
     5761 ttatttcaaa aaaagcacca tccaatcgct gtgatccaaa atccccaagt aggacaattc
     5821 aaattattcg atcagcatgt gcacagttgg acagtcaaag aaaatagctc tgtcgtccct
     5881 gcacagatct taacgccaga aaatctcagt gaagtactgg attcacctcc agcgtttctt
     5941 gttttcgatg gacagcacta cccaaaagat acagaggtgt ggaaacagtt ggcaggagtt
     6001 gattcgaaat ttttgatacc agatactagt cgctttcgca tctggctgcc cgaaaacaaa
     6061 attgtgatcc gtgactcttt tcaaacgaga aagcatgttg aaagttatgc agataaaaca
     6121 gatgactttt ttagtgatga ctatcttttt ttccacgcag acggatatat tggattttct
     6181 gatttcacga tcgaaggtag ccgttatttc gataaagggt tccctagccg agcgcttgct
     6241 atccatctaa cgtatattga tgcttacggc aatatacgcg tgaaacattt tgtctctgac
     6301 agtaacgact ctgctaaaga ccaagcattg aagtttcttg aagcaggaga taaaatgaaa
     6361 aaatggatca tgcgtcacca tcatcaactc ttgattactt caggaatgat tgaattattg
     6421 gctctttacc agcaacaaaa attccctgga ctgggagtgt tgaaaaagtg gtcacttatg
     6481 catcatttgg aacttattag tcacctgcta gatcatccaa aagattggct taaatattat
     6541 tcaaaagttc aggaactata tgaagtgatc caatgattag ataatgtaaa tgaaaaagga
     6601 atagaaaaga ggaaactgga tgtatattcg gcaaacaagg aaagaagaag tagaagaagt
     6661 ggtagaaatc attaatgccg cagcggattt cattgcttcg caaggctctc ctcaatggca
     6721 aaacgggcag aaaccaacaa aagaaacgat tttgaacgat attgaaagaa aagaaagcta
     6781 tgtattaata gtggaagatc aaattgctgg aacagctgca ttagtctcag gcgtggatcc
     6841 cgtttacaca aaaatagatg gtagttggaa agaatcaact ggtccttatt tatcgattca
     6901 tcgtgtcgct ttagcagaaa gtactcgagg aaaaaaacta gcaaaaccgt tcttagaaca
     6961 tttgttgacg attgcagcca gcaaaaatat ccaagatatc cgtatcgata cttatccagc
     7021 taatgaaccg atggaaaaga ccatctattc tgctggattc acttatcaag ggatgattga
     7081 atttcctttt gaacacggcg aaagaaaagc atatcaaata atcatcaatt gactataaaa
     7141 tcatctgagc aaagataaag acattaacac tactgaaaaa aacaatcata tgatagccaa
     7201 gaggttgtaa cagaagtggc cagcttcaaa aaacaagaaa gaatttccga aaatgcttct
     7261 caaatttttg tggaatttta gcgtatttta cgaaatagct gctttctgaa actcccttca
     7321 tcgagaggtc gtgacatagc ttttgtcacg atctctcggc ttatcctacg agtattattc
     7381 gatacattta tatcaataat ccttttttta ttttatctgc agcttcttgg aacgctccat
     7441 cgtttgacac gactaaaagt gaggggatag ctttcaaacg tttcaactgt gctaaatctt
     7501 ctacataaac cgccagtctg gctgaaatct gttcagatga atctccacgt tttttcaggc
     7561 gcgattgcaa tgtttcttta gagatcgtaa taaagatagg acggactacc gtcccgaaat
     7621 actcatataa atgccaaaaa ccatttgctg tcaaaacggc gtaacaattt cctactgtca
     7681 gtttcttttt aatttctgct ttactggaac catatttatg ttgagcatat tggtcccact
     7741 ctgcaaactc atttcccttg atcatctgat tgaatgtatt gtcagaaaca aaataataat
     7801 cctcttgatc tttttcccca ggtcttggtg atcgattcgt gtaagtaatg atcttttgtt
     7861 ccggctgaaa aatagcttct gcgagtgaag tttttccaga accagaagga ccgataaata
     7921 catagcaata attcattgtc atttctcctt tgatgattga acaagtgaaa aagctttgga
     7981 aaatatttcc aaagctttta aaagtaactt tgcttttttg tattttatac cagcaagcca
     8041 gtcacaatag cacttaaaaa gctgactaaa gtcgctgtta gcaaaatttt caatccgtgt
     8101 tttgcgacaa gatttccttt ttcttcattt aatcccttca tcgcaccaga aatgatcccg
     8161 atagaagaga agttggcaaa tgaaacgagg aagacagata taattgctgt tgtacgctca
     8221 gtaaaatgga aattaccatt tgctaattct gtcatagcaa caaattcatt tgtaaccagt
     8281 ttagtcgcca tgatactacc ggcatccact gcttctttcc atgggattcc gctgatgaag
     8341 gcaagagggg caaagatgta acctaggatc tcttggaaag tgatgccgaa tatcccgtgg
     8401 aagatagcat tgatcatggc aatcaaagca acaaaaccga taagcatagc agcaaccgtg
     8461 atcgccacat ggaaaccatc aagaatgtat tctcccaaca tttggaaaaa tgtctgttct
     8521 ttgttttctt caatgatcag ctcatcttct ttttcttcta atacataggg atttacaatt
     8581 gaagccagaa tataaccgcc aaataagttc aaaacaaggg cagtgatcac atatttagaa
     8641 tcgatcagtg ccatataaga tccgacgatc gacatagaaa ctgtagacat agccgataca
     8701 ctcatggtga acaaacgttt ctcagatagg aagggtaatt ccttttttat ggaaataaaa
     8761 acttccgatt gtcctaaaat agcagaagct actccattat aagattccaa tttgcccatc
     8821 ccgttgattt tacttaatcc tagaccaaca gctttcataa ataatggaag aatcttgata
     8881 tagcgtagaa taccgataat agcagaaata aatacaattg gcatcaatac ggaaagaaag
     8941 aaaggtgcac ttcctttatt tgctacaccg gcaaaaacaa agtcaacacc ttgcccagca
     9001 aaagcaagaa gatgatcaaa catttttgcc aatacagaaa caaccgctgt accaaaagtt
     9061 gtacgtaata atacgaaacc aagaacaagc tgtaaaacga acatcacaat tagtggtttc
     9121 aatttgattg cttttttgtt actgctgatc aaaaaagcaa gccctaatgt gacaaataaa
     9181 ccaataatac ctaataaata actcaaataa tcactcctat tccaaattcc gttttatttt
     9241 acctgttttg caaataaaat actaatcttt agtgaaattt tcattacttt tttagagtga
     9301 aacgcattca ttttccatta gaaaataaag cgaacaaaat aaaaggtt
//
LOCUS       DADVXB010000114         9053 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.117, whole genome shotgun sequence.
ACCESSION   DADVXB010000114 DADVXB010000000
VERSION     DADVXB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.117"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(28..291)
                     /locus_tag="KB902_002155"
     CDS             complement(28..291)
                     /locus_tag="KB902_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBB6808942.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(390..1685)
                     /gene="rho"
                     /locus_tag="KB902_002156"
     CDS             complement(390..1685)
                     /gene="rho"
                     /locus_tag="KB902_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBB6808943.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(1682..2953)
                     /locus_tag="KB902_002157"
     CDS             complement(1682..2953)
                     /locus_tag="KB902_002157"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6808944.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(3118..3987)
                     /locus_tag="KB902_002158"
     CDS             complement(3118..3987)
                     /locus_tag="KB902_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBB6808945.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(4279..5889)
                     /locus_tag="KB902_002159"
     CDS             complement(4279..5889)
                     /locus_tag="KB902_002159"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBB6808946.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(7082..8422)
                     /gene="glnA"
                     /locus_tag="KB902_002160"
     CDS             complement(7082..8422)
                     /gene="glnA"
                     /locus_tag="KB902_002160"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBB6808947.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(8450..8842)
                     /locus_tag="KB902_002161"
     CDS             complement(8450..8842)
                     /locus_tag="KB902_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6808948.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         2535 a         1955 c         1556 g         3007 t
ORIGIN      
        1 ctaaacgttg agttatcagc gtttttatta ttccgcagcg tttgcgtctt tgagaccgta
       61 ttttttgttg aaacggtcca cacgtccgtc tgcttgtgtg aatttttgac gtccagtgta
      121 gaatggatgt gagtcagaag ttacttcgac acggatgact gggtatgtat taccgtcttc
      181 ccattcaact gtttcttgtg aagtttttgt tgaacctgac aagaatttga aaccagttgt
      241 tgaatccatg aatactactg ggtggtaatc tggatggatg ttttctttca tgattttttc
      301 gctcctttgc cctgctccat ttgctgaacc agagttgatt tgtcgattta caacattaac
      361 atcttaacat gtttcagtca aggttgcaat tatcttttca gatttctggt cggatttttt
      421 ttaccaaagg agacatcttg aaattctttg aaaaattgct gattgttttt tgttttacgc
      481 aaaaagcgga tcagttgttc cgtatattct aatgaatctc cagtcatatt ttttcgaagt
      541 ttccaaattt cttctaattc ttcacttggc atcaataatt cttcttttcg ggtacctgat
      601 tttttgatat cgatggctgg gaagatccga cgttcagata attcacgtga aagttgtaat
      661 tctagatttc cagttccttt gaattcttca tagatcacgt catccatacg gcttcctgta
      721 tcgactaaag cggtcgctaa aatcgtcaaa ctgccacctt cttcgatgtt tcttgctgcc
      781 ccgaaaaatt tcttaggttt atacaatgcg gctgggtcaa tcccgccact caatgtacgt
      841 ccgcttggtg gaacgactaa gttataggcc cgagcaagtc tagtaatact atccatcaag
      901 ataacgacat ctcgtttatc ttcgactaaa cgcattgcgc gttccaatac taattcagaa
      961 actcgagtat ggttttgcgg ctgcagatca aatgtagaag ataccacgtc gcctttcacg
     1021 cttcgttcta gatccgttac ttcttccggt cgttcatcaa tcagtagaac gattaattct
     1081 acttccggat agttttcggt gataccattt gcgatttctt ttaatacaga agttttccct
     1141 gcttttggcg gtgcgacgat caatccacgc tgaccaaaac cgattggaga aaagatatcg
     1201 atcattcggg tagatagtct ttgcggtgtt gtttccagtt gaagctgtct ttgcggataa
     1261 agaggtgtta aggctggaaa atgcggacgt tcttttgctt cttccggatc ttttccatta
     1321 acgctttcca cgtgcatcaa accataataa cgttccgatt ctttaggtgg acgggctttt
     1381 cctgccactt tgtccccatt tctcaaactg aatcgtctga tttgtgaggc agaaatatag
     1441 atatcttctg cacttggtcc ataattgatt ggccgtaaaa aaccgtaacc atcttgacca
     1501 acgatatcca atattccttc catataataa aatccttgtt tctctgcttg tgcacgaatc
     1561 acagctagag ataattcctt tttattcatc ttactgtaat aaggaatttt aaattctttg
     1621 gcataactat aaacttcttt taacgttttg ttctctagtt ctgccattgt caaataatcg
     1681 ctcattcagc tcccacttcc tctatcattt caattgatgc ccctaaggct gttagtttct
     1741 cgataatatg atcataaccg cgtaagatat aatctacatt gtaaatcgtc gttgtccctt
     1801 ctgccaatag tccagcaatc actaaacaag cacctgcccg aagatcagaa gccacgactt
     1861 ctgtgccgtg aagtttattt ggaccattca cgatgatcat atttccttcc acggtaatat
     1921 cagcgcccat tcgtgctagt tccggcacat ggttcacacg tttcgcatag atcgtatcga
     1981 tgatttctga agtgcctgta gtcatcaata gtaacgcagt aagtggctgc tgcagatctg
     2041 tggcaaatcc tggataagga taggtcatga tgtttgcggg ttttaattct ttcgaggggt
     2101 aaacttcgat ttcatcttcg ctgattttca tatggacacc aatttcctgc aattttgcta
     2161 taaagctttc caaatgttca aagatcacat ttttcacttt gataccattt cctactgcag
     2221 ctgctaatgc tagataggtt cctgcttcga tgcggtcagg aatcatgaaa tgccgacagc
     2281 catgtaatgt ttcgactcct tcgatacgga tcacatctgt acccgctcct cgaacttttg
     2341 cccccatatt attcagtaaa gttgccacat ctatgatttc cggttctcgt gcagcgtttt
     2401 caattactgt ctgtcctttt gcttttacag cagctaacat cacattgatc gttgctccga
     2461 ctgaaaccac gtccatgaaa atccgattgc cacgcaatcc tttattttct gtccgtaaat
     2521 acatggcacc atgttcattt gtcacttcag cacctagagc ttcaaatcct ttgacgtgta
     2581 ggtcaatcgg tctagggcct aaataacagc cacctggcag gcctactacc gcttcgccaa
     2641 atttaccaag cagtgttccc ataaaataat aagaagcacg caaactattg atttttccgt
     2701 gcggcatcgg aatcgatacg acttctcgag gatcgatttc tagtatgttg ttggaaaaat
     2761 ggacagttgc gcccatgatc tctaaaattt caattaatga atgaacatct tgtatgtccg
     2821 gcacaccttc caagatcact ggggaatcag ctaagattgc agctggaatc aatgcgactg
     2881 cactattttt tgcaccgctg atcgttactt caccagctaa aggtcggttt cctttgatta
     2941 cgattttttt catctgtttc caccttgttt attaatcttt tttcatggat atgcttgtat
     3001 tttatcatag ataaaaaaaa gaaacgagca tggtctgccg ttttaagtaa aaaagaatgg
     3061 agagcgactt caaaagtcgt tctccattcc tatatatcgt atctgttatg tggatgctta
     3121 cgctttgtta gctgaaccga accagtcgat atgagattta gcatcttcaa cgattgctgc
     3181 tttacctgga gctaataatt tacgagggtc gaatccttta ccttctttat ctttaccagc
     3241 ttcgatatat ttacgagtag ctgcagcaaa tgataattgg aattcagtgt taacatttac
     3301 ttttgagata cccattgaga tagctttttc gatttgatct tgaggaatac ctgatccgcc
     3361 atgtaatact aaaggcatgt ctggacctac agcatcagca attgcttgta agtggtcaaa
     3421 agctaatcct ttccagtttt ctggatattg accatggatg ttaccgatac cgcaagctaa
     3481 gtagtcgata cctgtagcaa ccatttgttt gcattcttca atatcagcta attcgccgtt
     3541 accgatgatt ccgtcttctt ctccgccgat tgaaccaact tcacattcaa ctgagatacc
     3601 ttttgcatgt gctttttcaa caacgtcttt agctaatttc aagttttctt caaatggtag
     3661 atgtgaacca tcgaacatta ctgaagtata gcctaattcg atacattcca aagcagcttc
     3721 gtaatcacca tggtctaagt ggatagcaac tggaacagtg atgttcattg cttcaactaa
     3781 atcagtgatt aaatctttac agattttgta accacccatg tatttagctg cacccattga
     3841 tgtttggata agtactggtg cttgttttgc ttcagccgct tcaaggattg cttgagtcca
     3901 ttccaagttg tttgtgttga atccgccgac agcgtaaccg cctttacgag cagcttttaa
     3961 aaattcagct cctgatacta ctggcataat aaaattcctc ctaagttttg taaaactaaa
     4021 tttgttaaga caattcttaa ccaacgaccc tattttacca aacatttcgg tagttttcta
     4081 ctaaaatcaa tgaaaatgaa aattttcaag aagttttttg caaaaaataa aatatccaat
     4141 agcgctttaa tcgaaaaaag tcttttgctt tctatctttt ttcctacaaa taataacaaa
     4201 tcagaaaaag agaaaagtga caagaaaatt gcttatcccc ttctcttgct acttttctct
     4261 ttctatcaag ttcaaaaatt attttgtttc gtgatctgct aatgatgctc cgacaaatgc
     4321 tttgattaat ttttgcgggc gatttggacg agaaatcaat tctgggtgga attggcatcc
     4381 cacaaagaat tttttctctg gcagctctac gatttctact aaacggttat ctggtgagac
     4441 acctgaaaag actagccctt gttcttcaaa caattgacga tatttgttat tgaactcata
     4501 gcggtgacgg tgacgttctt gcacaacatc ggctccatca tatgcttcag ccgtcttcgt
     4561 tccttttttg attttacatg ggtataatcc aaggcgtaaa gttccaccca aattctcgat
     4621 gttttcctga tcagccatta aatcaataat attgtttgct gtatctggat tcgtttcagc
     4681 tgatgacgca tcttctaatc caacgacgtt acgtgcaaat tcgacacaag ccatctgcat
     4741 accaagacaa atacctaaaa acggaacgtc attttcgcga gcataacgaa tcgcttcgat
     4801 tttcccttct actccgcgat caccaaatcc accaggaacc aagattccat ctgcgtcttt
     4861 caaacgttct tctacatttt ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat
     4921 gtctgaatta taggcgaaac cagaatgttt caatgcttca actactgaga tatatgcatc
     4981 tggtaactcg acatatttac cgacaagcgc aatccgtact tttttcttca agttcaagac
     5041 acgttcttct aattctttcc attctgtcat gtctgcttct ggtgtatcta gttttaaatg
     5101 gtcgcaaaca atttgatcca ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt
     5161 atctacatct ggcgactcga taactgcttc tggttcgaca tcacaaaatt gtgccaattt
     5221 gtttttcacg ctttgagaaa caggttgctc tgtacgtacc accaaaatat tcggttggat
     5281 acctaaacca cgtagctctt ttacactgtg ctgcgttggt ttagttttca tttctccagc
     5341 agctttcaag taaggaatca atgttgtatg gatatacata acattatctg taccgacatc
     5401 tgctttcatt tgacgaagtg cttcaaggaa tggcaaagat tctatatccc ctactgttcc
     5461 ccctacttct gtaatgatca catctgaatc agtcatttta gctgctcgca tgattttttc
     5521 tttgatctca tttgtaatat gaggaataac ttgaacagtt gctcccaagt attcgccctt
     5581 acgttcttta cgcaaaactt cagaatagat ttttcctgtc gtcacgttgg agtatttgtt
     5641 caaattgatg tcaataaaac gttcgtagtg gcccagatcc aaatctgttt cagcaccatc
     5701 atctgttacg aatacttctc cgtgctgata tgggctcatc gtccccggat ccacgttgat
     5761 gtatggatca aatttttgga tagttacttt taagccgcgg tttttcaata agcgtcctaa
     5821 agaagctgca acaatccctt ttccgattga tgaaacgaca ccgccggtca caaaaatata
     5881 ttttgtcata agttcaaaaa ctccttttta atttatgtgc aggaaaagtc tcagacaata
     5941 aacaaagctc cctattcttc aataagaata gggagccgaa atttctgtaa acttctgacc
     6001 ctctaaaagg gtgcccaagg tgtataatac aagctgacta agggaaagtc aagtactcaa
     6061 atgaatacta tccgcttaca attttttctt tttcgatatc ctttgagaaa ttatttctta
     6121 agtcctttat gagtgcaaaa aaaatttaac ccacataata agcttgatat aaacatagct
     6181 aacgttaaac ctaagcaaat cagaaaatcg ttactgaaaa attttaagtg aaataataga
     6241 taaaaaaata aaacaaacat tatgatagat aatatcccac ctaacaaaga actacttttt
     6301 cctacttgca gcaacagttt atatagctta tcgtagaaac aatctttttc tttcaccctt
     6361 atttacctcc tttacgtaaa aaacgtagtc cacagttctc ggatttttgg catatctttt
     6421 ctattaaata atatcaaaaa caaaacaatt ccactaattt tttcaaagat gacctttttt
     6481 tcaacaaaag tgccttgtag ggattcattg aaggtaacga atcacataag taaaaaataa
     6541 ggagatgcga caaaagtcgt gcctccttat ttctaaataa acggtgttct cctgccaact
     6601 cctcggtcac aagtcacaat atccatcaaa catgagaagc tgtttttgaa attatttctt
     6661 gtgattcgga gttaaatggt aggctcacaa cctctggata aacggtattc aaaagccagt
     6721 ttctcggtat taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc
     6781 ttaatactcg aaactaaacg tctttttcaa aacctcttgg taaacggtgt tcaaaagctt
     6841 gcatctgcgg taataagttc agccaattca aaaacaagaa aagctgtttt tgcttggcta
     6901 ttcttattac ttgttgcagg gcagcttttt cacaacctct ccactaaacg gtgttcaatc
     6961 agctgaccct cggtattagc tcaaaaaacg gcaaaatatg aggaactatt tttccgttag
     7021 tttctctaat actcaggtca aaacgctgat ttcacagcct ctaattcacg gtattcctgt
     7081 tttaataaag ttctagatat tgttctcttt cccactcgga aacagtttgt ctgaatgccg
     7141 cccattcgag acgttttgct tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa
     7201 tcattacatt atccttacgc aattctttga tagcattatg gatagttgaa ggtaagtcct
     7261 ggatatgtgc agcttctctt tcttcctcat ccattacata aatgttacgg tcaacagctg
     7321 ctggcggtgt gatctgatta cggataccgt ctagtcctgc ttgcaacaat actgccattg
     7381 ccaagtatgg gtttgcagat ggatcaactg accgcaattc caaacgtgtg gataaaccgc
     7441 gagattctgg tacacgtact aatggcgaac gattacggcc actccatgcg acataaacag
     7501 gcgcttcata acctggaacg agacgtttat aagaattgac tgttggattg caaacggctg
     7561 tgtaggcacg agcatgtttc agcaaaccac ctaagaaatg ataagctgtt tcacttagtt
     7621 ccaattcacc gtctttatca tagaaaacat ttccttcatc attgaacaaa gacatattgc
     7681 aatgcatacc agaaccattg atcccaaata acggtttcgg catgaaagtc gcgtgaagtc
     7741 catgcttgcg tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta tcacaagcat
     7801 ctaccacatc tgcatattta aagtcaattt catgctgtcc tggcgctact tcatgatgtg
     7861 aagcttccac ttcaaagcct agactttcta attccaacac gatgtcacgg cggcaatttt
     7921 cacctaaatc tgttggtgca aaatcaaaat aaccaccttt atcattcaag gtcgttgtga
     7981 tcccaccgtc ttcgtctaat ttaaataaga agaattctgg ttcaggtcct aaattgaaag
     8041 aggtaaaacc aaggtcgcgc atatctttca atgctcgttt caaattcccg cgaggatcgc
     8101 cggcaaatgg tgtcccatcc ggattataga tatcacaaat taaacgagca acttttccat
     8161 gagcactttc ccacgggaag atcatccaag tggagagatc tggatacaaa tacatatcgc
     8221 tttcttcaat tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt ttattttcta
     8281 atactttgtc gatctggctc actggaactt ctacattttt gatcgtacct aagatgtctg
     8341 tgaacatcaa tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg atttcttcac
     8401 ctgttatctg tttctttacc atggtatccc tcttcctttt ttaatttatt cagtcaaaga
     8461 attgtctttg caatccttgc gactgataat gacctgtttt gcttaaccca ccttgcgcca
     8521 aaatctcatc acgaaaaatt tgtcgaacgt catgatctgt caacggcttc ttgttttttg
     8581 cttcttgttt tttcgcctgt gccatttcgt atacacgttt gatcccagcc atattcaatc
     8641 cctctgaaag atagtcttta atctcaagca acatatcaat atcattcagc gaatacatac
     8701 gtcggtttcc ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa tagcgaattt
     8761 gccgagcaga caaatcagtc agcttcataa ctgtaccaat tggaaatacg gacatagatc
     8821 ggcgcaattc cttttctccc atcagacgtc ccctttcgtt ttataagttg gctaaagtgt
     8881 accaattaaa aaaaatattg tcaactgcat atgttaggtt ttctaacatg agatctctat
     8941 tttttataaa ataacaaaaa aataagaaca caaaaaaggt atctagttga ttttcgtacc
     9001 agataccttt tattttttat tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DADVXB010000115         8998 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.118, whole genome shotgun sequence.
ACCESSION   DADVXB010000115 DADVXB010000000
VERSION     DADVXB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.118"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1230
                     /locus_tag="KB902_002162"
     CDS             <1..1230
                     /locus_tag="KB902_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6808949.1"
                     /translation="LVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRF
                     ISISLFYVFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLL
                     LFLTAGVILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTK
                     EFLATEAVIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSS
                     NGYRFYSRFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFIS
                     DEDIQEIRETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWM
                     IQQDSLFTKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNF
                     SFRFAFRAKSKKTSPIK"
     gene            1390..3276
                     /locus_tag="KB902_002163"
     CDS             1390..3276
                     /locus_tag="KB902_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6808950.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            3288..4235
                     /locus_tag="KB902_002164"
     CDS             3288..4235
                     /locus_tag="KB902_002164"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6808951.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            4255..4782
                     /locus_tag="KB902_002165"
     CDS             4255..4782
                     /locus_tag="KB902_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6808952.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4845..5498)
                     /locus_tag="KB902_002166"
     CDS             complement(4845..5498)
                     /locus_tag="KB902_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6808953.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKLERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            5630..6472
                     /locus_tag="KB902_002167"
     CDS             5630..6472
                     /locus_tag="KB902_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6808954.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            6630..7526
                     /locus_tag="KB902_002168"
     CDS             6630..7526
                     /locus_tag="KB902_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6808955.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            7529..8242
                     /locus_tag="KB902_002169"
     CDS             7529..8242
                     /locus_tag="KB902_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6808956.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            8262..8780
                     /gene="msrA"
                     /locus_tag="KB902_002170"
     CDS             8262..8780
                     /gene="msrA"
                     /locus_tag="KB902_002170"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6808957.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            8777..>8998
                     /locus_tag="KB902_002171"
     CDS             8777..>8998
                     /locus_tag="KB902_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6808958.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHD"
BASE COUNT         3199 a         1544 c         1838 g         2417 t
ORIGIN      
        1 ttagtattta tatttttagg aatcgaattg acgcaagtgt tctcgccagt atggggagac
       61 ggtttatatc caaacggtct tttattagcg attatcgtat taatctctgt catgcttttt
      121 gtgatcagat tcatttctat cagtcttttt tatgtattca aagatggcag taaaaagttc
      181 aaaaaacagt tgaacgagat cttgatctta acatttggcg gtgtaaaggg aacagtcagt
      241 ttggctacga tttttatttt gccattttca atcaataata tgatgtttta ccagcggtct
      301 ttgcttttgt ttctgacggc gggtgtcatc ttagtgactt tggtcatagg gatcattgtc
      361 ttgcctatgc tgacggaaac agaggaagcg aaaagcacgg atttgaatgc tttgatgatt
      421 ttagaagagg tcgttgaagt tttgcgaaaa gaaataaagg aaattgatcg taatacaaaa
      481 gaatttttag ccactgaagc agtgatagaa aattatcaag aacggatacg tgatctgtac
      541 ttggaagatt taaccgatga tgaaaagcaa gaagtacaag aaatacaagc actgattttg
      601 tcgatcgaac gggatggatt ggatgaaagt tatcgttcgg gcaagctttc ttctaatggt
      661 tatcgttttt actcccgttt tctttctcga ttcgaacatt ctatcacaag ccagattttg
      721 tcttttatcg gcttttggtt cattgttgtc cgtaggttaa tgcgaatcgt tctccatccg
      781 aaaatgtttt ggcaaagaag atatgctgat cgtcagacat ttattagtga tgaagatatc
      841 caagaaatca gagagacata tcaaaaaaat actcagttga ttattgaaag tttagataac
      901 ttgactgata tttatgatga aacgatggtt caatttttta tccagcaacg caaacttgaa
      961 ggaataaaaa tgaactcggg gaatttgatt tcttcgtgga tgatccagca agatagtctg
     1021 tttacgaaaa aaatgctaag aggttattat cttgaaagaa aaatcattga tgaatacgaa
     1081 gttgctgaaa aaatcacgac gttttctgcg aacagctatc gcaggaatat caatttgtta
     1141 gaatcttata cgatgaacaa accatctgat aacttttctt tccgatttgc gtttcgagca
     1201 aagtcaaaaa aaacgagtcc aataaaataa aaaggtaaaa attttcaagt tttataaaaa
     1261 acaaaacata tcagaacagg atcgaatcgg tcctgttctt tttttgagaa cacaaaaaga
     1321 acaaatacca aaaaaatttt cctgaagttc actattttta tgatacaata tccaagataa
     1381 ggagggaaca tgttgaaaga attaaaagta actgacctca aaaaaactta tggtgaaaaa
     1441 gatttgtttg accagatttc ttttttggtc cacgaaaaag accgtatcgg gttgattggg
     1501 acgaacggga cgggtaaaac aagtctctta aatattattg ccggtatcga tagcagcgac
     1561 ggtgatcggc aaacagtgtt ttatccaact gattaccgta ttggttatct ttctcaagca
     1621 gctgaatttt ccgatgaatt aactgttctc caagcagtct ttcaaggaaa cagccccttg
     1681 atccaaactg ttcgagcata tgaggaagca ttgatcgaac taggggaaaa cggagaagac
     1741 cctgatgtgc aaaaacgtta tgctaaagca gaagaacaaa tgaataaaga agatgcttgg
     1801 actacagata ccaacgcaaa gattattttg caaaaattag gaatcagtga attagataaa
     1861 aaaatcagta ctttatcagg tggtcagaaa aaacgagtta gtctggcgca agtgttgatt
     1921 gatgaacccg atttactatt actagacgaa ccaacaaacc atttagatta tgaagcgatc
     1981 gagtggttgg aaaactattt gaaacaatac cgtggcgcac tattgatggt tacccacgat
     2041 cgttattttc tagatagagt agcaaaccga atcttcgaac tttcatttgg aaaattatac
     2101 gagtataaag gaaattatga agcttacgtc ttagaaaaag cagaacgtga tcgtgtagaa
     2161 gtagaacaag aagaaaagcg caagcggctt tataaacagg aattagcttg gatgagggct
     2221 ggcgtacagg cacgtggcac caagcagcaa gcacggatca accgtttcga agatctaaag
     2281 gagaacttgt accaagtaaa ccaagaagat gatttagagc tgaacctagc gacacaacgt
     2341 ttagggaaaa aagtactgga aatcaaagat ggcagttacc gtataaatga ccaaacactg
     2401 ctagaacatt tagatttatt gattcaatct cgggaaagac taggtattac tggtaaaaat
     2461 ggtgcgggaa aatcgacatt gcttaatatt ctagctggca gaattcccct ggatagcggt
     2521 acaatgtcta tcggtgaaac ggttcatctt gcgtattata cacaagaaaa tgaagaaatg
     2581 gcaccagata aacggatgat tgcttactta caagaagctg ctgaagaagc aaaaacagca
     2641 gatggcagtc aaatcggagt agcagaatta cttgaacgat ttttatttcc aagatttatg
     2701 catgggacac tgataggcaa actttcaggc ggagaaaaac gccggttatt tttgttgaaa
     2761 ctgctgattc agcaacctaa tgttttatta ttggatgaac cgaccaatga tttggacata
     2821 gcaacattga cgattttgga agattatttt agaagttttc caggtgctgt gatcactgtt
     2881 tcccatgacc gttatttctt ggacaaggta gcagataagt tattagtatt ccaaggaaac
     2941 ggaaaacaag aactttatta cggaaacatg tccagttatt tactgaagca aaaagagacc
     3001 cagcagcctg ctgaaaaagc gaaaccaaaa atacagagca aggaacctgc tgaaaagaag
     3061 aaattatctt acatggaaca aaaagaatgg gaaacgattg aagatgagat tgcagaactt
     3121 gaagaaaaaa tctcattgct ccaagaagag atgaatcatc aaggagataa tttcactcga
     3181 ttacaagaat tgcaaaacga cgtatctgaa acagaagcac aacttgaaga aaaaatggca
     3241 cggtgggaat acttgagtga atgggtagaa gattaggagg aaaaaggatg gaacaagcgt
     3301 atcttgactt aggaagaaaa ttgttggaag aagggcatcg taaagaagac agaacaggca
     3361 caggcacatt aagcttattc ggataccaaa tgcggtttga tctgcaaaaa gggtttcctt
     3421 tgttaacaac gaaacgagta ccttttggat tgatcaaaag cgaattgctt tggtttttaa
     3481 aaggagatac gaatatccgc tatctattac aaaataaaaa ccatatttgg gatgaatggg
     3541 catttgaacg ctacatcaaa agtccagact ataatggacc agatatgact gattttggcc
     3601 atagatgttt gacagatcct gaattcaatg aagaatataa aaagcagagc aagctttttt
     3661 gcgagaagat cctaaccgat gattcctttg ctgaaacata cggcgatctt ggacacatct
     3721 acggctatca atggcgtcac tgggaaacaa aagacggtgg ctttatcgat caaatcaaac
     3781 aagtgatcga agcaatcaaa aagactcctg attctagaag attgatcgtt tctgcatgga
     3841 atccggaaga tgttcctagc atggctttgc ctccttgtca tacgatgttt caattttatg
     3901 ttcaagaggg acggctaagc tgccaattgt atcaacgcag tggggatgtg tttctaggcg
     3961 ttccgttcaa cattgcaagt tatgcgttgc tgactcacct aattgcacat gaaacaggtt
     4021 tagcggttgg cgaatttgtt cacacattag gagatgctca tctttatatc aatcatatcg
     4081 aacaaatgaa agaacaattg agccgagaaa tacgcgcatt tccgacttta gttttgaatc
     4141 aggaaaagca gtcagtattt gattttgaga tggaagatat ccaattagaa ggatatgacc
     4201 cacatccggc gatcaaagct cctatcgctg tttagaatca gaaaggatga gaaaatgtta
     4261 gctgcaattt gggcacagga tgaaaacgga ttgattggaa aagaagaccg tcttccttgg
     4321 cgtttgccaa atgatctgaa attcttcaaa caaatgacag aagcaaatac actagtgatg
     4381 ggacgaaaaa cattcgaagg gatgggtagc cgtccgttgc cgaatcgtca gacgattgtt
     4441 ttgacgagag attcttccta taaagcagaa ggcgtgcatg tcatgcatag tgtggaagac
     4501 gtgcttgctc tggaaaaaga aacagacggt atctttttca tcgctggagg gtcagctgtt
     4561 tatcaagaat ttctgccatt ttgtacgata ttataccgta cagtcatcca tcatgtattc
     4621 gatggagatg cttattttcc acctgttgac tggtctgatt ggtcactgat caatactagt
     4681 caaggagaaa tggatgaaaa aaatcgttat ccgcatcaat ttgaaacgta tcagcgtaat
     4741 gagaatcctg taaaaagcgg gacaggcgaa ttgacgatat aaaaaagcta tggatagact
     4801 agctgttatt tagagctgtc ccatccatag ctttattttt tttattaagt aaagaataaa
     4861 acagagaagt acataaaacc tgcacctaac ataacaaaca aatgccaaac aacatgcata
     4921 tagcggatag aattcaagct ataaaagaat gcgcctatcg tgtaagaaag cccgcctgct
     4981 accatcaaaa taacaccagt cattccaaga gagtgataaa gaggaacagc agccacgaca
     5041 cagagccacc ccataaaaat atagatgatc gtagatactt ttgatactct ctccagttta
     5101 tgcaacgtca acgctttata tataatgcca agaatcgcaa acaaccagat taatacaaat
     5161 aaagtccaac ctagccatcc tcggatactc agcaaacaaa aaggagtata acttcctgca
     5221 atcaaaagaa aaatcgaact atgatcgaat acttggaaca ccttttttgc ttttgtaaaa
     5281 atcaatgaat gaaacaaagt agacgttaaa aataaaagaa tcatcatcga tccatagata
     5341 gcataagaga caatatggag ggaggaatgc aagtgggcac cttttactaa aagaaccact
     5401 agtcccgcga tactcaatcc agtcccaatt ccatgggtga ctgcattaaa cacttcattt
     5461 aatatttcat acgttcgatt aaatttcgtt ttttccatga aaacggctcc tttactaggt
     5521 gtaattaatg aaaaatcatt atttgtctgt tatactaaaa atagaaattg tcttacatgt
     5581 agtttaacat gaataaggca tcttgttaaa gaaagagaga gagaaaataa tgacaaatgt
     5641 aaaaatcgta acagattctt catgtacgat ggaaaaaaat gtacgcgatg ctttaggcat
     5701 tcgtgtcatg ccgctatcca tcatgatcga cggaacagta tatcccgatg atgaccaact
     5761 agacggcgaa agatttatgg aaatgatggc gaaagcaaaa aatctgccca aaacaagcca
     5821 accaccaatt ggagaattca tctcgatgta tgatgagcta ggagaagacg gcagtgaagt
     5881 gatttcgatc catatgacaa aaggcttgag tggaacagta gaagcagcaa gacaagccag
     5941 taatctaaca aaaacgaaag taacggttat cgacagtgat accactgacc aaggattatc
     6001 ttttcaggta attcgagcag ctgaattagc aaaagaaggt aaaacagtag agaaaatcct
     6061 tgaagaagtc aaaaaagtac aagacaatac aaaattatac atcggaatat ccacactaga
     6121 taacttggta aaaggtggaa gaatcagccg aacaactggt ttgctgtcta gtgttttgaa
     6181 catacgcgtg gtgatgaatt tcgcccattc tgaattaatc cctgtaacta aggggcgagg
     6241 aaagaaaacg ttcgataaat ggtttaataa tttgaaaaat gaactgaaag aattgccaaa
     6301 tgtgcgacaa atcggtattt cacatgcgga tgcaaaagaa ttggcgcaag aattcaaaga
     6361 gggtttgcaa gaattattcc cggacatgca tatccctgta ctgcatacga atccggttat
     6421 cgctacgcat actggtaaag acgcgtttgc aatcatgtat tatgtagatt agtcgaaaag
     6481 aggataagcc ctcagcctga aaggcttgca gcttattctc tttttcttta taaaattagg
     6541 aaaataattg ttttcttttt tcataaagac tacctttttg ataaaatttt tgataacatt
     6601 agaaccaatc gaatacaaga ggtgaaaaaa tgaaattaac gaaacgacat ttgatcctcg
     6661 ttttgttccc attattaatt gcgatcatca tctatgcagg tttagctgct tctataccga
     6721 aagctggccc actaatgaaa ccagtaacta ctgtgagaga agatccaaat aaaaaagaaa
     6781 aacttcacta catagctatc ggagattcgc tgactgaagg agtaggagat caaaccaagc
     6841 aaggaggatt cgttcccctt gtcgcaaatg atctaaaaga ccgttataat ttgaccgcgg
     6901 ttgaaacaga aaactatggt gtaaatggtg aacgaagtga ccagatctta aagcgagtaa
     6961 aaacaaaaga agaaattcga aacaatatca aaacagctga ttttatcaca ctgactgttg
     7021 gcggtaatga tttgatgaaa gttatccaaa ataatttatt cgggttaacg gtcaattcct
     7081 ttaaaaagcc actgaaaaac tatcaggaaa atgtcacaga actattggaa gaatttcgat
     7141 ccctcaataa aaccgcacct atttacattt taggcatcta caatccattt tatttgaact
     7201 ttcctgagat cactgacatg cagacaattg ttaacaattg gaacaaagga acagaaacgg
     7261 tgacaaaaaa aatgccgaac tgctacttta tcccaatcaa tgatttgctt tatcaaggat
     7321 tgaatcagga agtaggtgtc acagaagaag gaacagatca aacaactagc acgacagaaa
     7381 atctaaatgg catcaaaaat aatgtgctct atgaagaaga tcatttccat ccaaataatt
     7441 taggttatca attgatggca aatgcagtga gagatcagct gatcgagaca caaaaccaat
     7501 ggttagagaa ggaggatgat caataaacat gaaaacaaga tctgacgtat cttcaaacaa
     7561 aacaaagaaa acaaattact ggaaattcgc cttccttatc cttcttgggg tagtacttgg
     7621 ttcgaccgta tttttaggca gccgtatttt tgctaatcgg gaaccagaac tcccagaaat
     7681 accagctctt acggaaagac aaggagatcc tgtcttaacg atcaattcaa ataaagaaaa
     7741 agtcaatcaa atcatcagct ttttccttag tgagtatcaa aaagatagtg atattgaata
     7801 taaattttat ttggaaaatg aagcactact caatggtact ttcgaagtac taggttttcc
     7861 tatcgatttc tatttatatt ttgatccgta tgtgatggaa aacggaaatg tccaactaaa
     7921 agctagaagt ctttctatcg gaacattgag tttgccaatc aaagatgtga tgaatatgat
     7981 caagagaaac tataaattac cagattggat cgaagtcaat acagatgatc tgactatcat
     8041 gcttaggttg gatcaattcc gaatgcaaaa cgggatgtat attaaagcag ataaaatcga
     8101 cttagtaaat gatgacattc ggtttagtct atatttgcca aaagatacct ctgatgcttc
     8161 aaacaactca aataccaaca aaactagcac cagcagtact gaaagcaaga caaaagaaaa
     8221 taaaaaatca tcggatgagt agtattagag ggggaatcat aatggaacga gcaatatttg
     8281 caggaggctg cttctggtgt atgatccagc ctttcgacac gcttcctggt atccatacag
     8341 tgatgtcagg atatactgga gggcatgtac cagatccgac ttatgaacaa gtaaaaagcc
     8401 aaacgactgg acatacagaa gcagtggaga ttatctatga tccaacattg atttcatatg
     8461 aacaattagt agaactttac tggcagcaaa ctgatccaac tgacgctttc ggacaattcg
     8521 aggatcgcgg tgacaattat cgcccggtga tcttttattt gacagaagaa cagcggatca
     8581 ttgctgaaaa aagtaagaaa cagttagctg aaagtggacg tttcgaacag ccaatcgtta
     8641 caaaaatcga accagcccaa ccattttatc tagcagaaga agaccatcaa gagtattata
     8701 aaaagcatcc tgaaaatttt aaaagaaacc atgcacgccg ggctgccttt atcgaagaaa
     8761 attggaggaa cgaagggtga atcgaagctt ttttcattat ttaatgacac tgcgaggcgg
     8821 tggcacacat gatgctttat ctgttttcgc tacagaagcc ggtaaagaca tccaatttcc
     8881 taagcacagc tctagctacg aagaaatttc taattatctg gaactgaatg tcgactattt
     8941 gccgtccatg gatatctttg acgaagcatg ggaaaaatat ttagaaaata atcatgac
//
LOCUS       DADVXB010000116         8915 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.119, whole genome shotgun sequence.
ACCESSION   DADVXB010000116 DADVXB010000000
VERSION     DADVXB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.119"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            11..84
                     /locus_tag="KB902_002172"
     tRNA            11..84
                     /locus_tag="KB902_002172"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Ile,seq:cat)
     gene            complement(469..966)
                     /locus_tag="KB902_002173"
     CDS             complement(469..966)
                     /locus_tag="KB902_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6808959.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1006..1815)
                     /locus_tag="KB902_002174"
     CDS             complement(1006..1815)
                     /locus_tag="KB902_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6808960.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2149..3006
                     /locus_tag="KB902_002175"
     CDS             2149..3006
                     /locus_tag="KB902_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6808961.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2999..3901
                     /locus_tag="KB902_002176"
     CDS             2999..3901
                     /locus_tag="KB902_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6808962.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3934..4284
                     /locus_tag="KB902_002177"
     CDS             3934..4284
                     /locus_tag="KB902_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6808963.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4333..5256
                     /locus_tag="KB902_002178"
     CDS             4333..5256
                     /locus_tag="KB902_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6808964.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5334..6227
                     /locus_tag="KB902_002179"
     CDS             5334..6227
                     /locus_tag="KB902_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6808965.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6265..6828
                     /gene="amaP"
                     /locus_tag="KB902_002180"
     CDS             6265..6828
                     /gene="amaP"
                     /locus_tag="KB902_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6808966.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6842..7030
                     /locus_tag="KB902_002181"
     CDS             6842..7030
                     /locus_tag="KB902_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6808967.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7043..7945
                     /locus_tag="KB902_002182"
     CDS             7043..7945
                     /locus_tag="KB902_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6808968.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7977..8219
                     /locus_tag="KB902_002183"
     CDS             7977..8219
                     /locus_tag="KB902_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6808969.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8475..8846)
                     /locus_tag="KB902_002184"
     CDS             complement(8475..8846)
                     /locus_tag="KB902_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808970.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3096 a         1548 c         1736 g         2535 t
ORIGIN      
        1 tatttatgat gtacctttag ctcagttggt tagagcagac ggctcataac cgtccggtcg
       61 taggttcgag tcctacaagg tacataagag gttgtgaaaa agctgccctg catcaagtaa
      121 taagaacagc caagtaaaaa cagcttctta tgtttttact tggctgttct tattactgca
      181 gatgcaagct tttgaatacc gtttaaggaa gaggttgtga aatcagcgtt ttgacctgag
      241 tattagctta acaaacggaa aaatagttcc tcatattttg ccgtttgtta agctaatacc
      301 gagggtcagc tgattgaaca ccatttaaga aagaggtcgt gagcctgccg tttcactctg
      361 tgtcataaaa aagccaatct actttgatag aaaaagcacg taggactaaa acagttctgc
      421 gtgctttttt tattgtgtgt taaatatcgt aaatgaagat agatattttt atgattcgac
      481 gatagagacg ttgaaatctt tcaacagctc taaagcggat tctccgtgtt ttctactgga
      541 gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa gcactctgca ggcctatcag
      601 attagagagt acacacaagt ttgtttcaat cccgactact tcgatctctt tttgttcttc
      661 tttgctttca aataaagttt cctggatttc agctaaagtt tcaggtggaa tcgtaaagta
      721 atacttttta atcactcgtt cattttcttg tggagaaaga agagggatca attgcaaatc
      781 ttctcgttct tcttctttgt ccttcagttc aactggtata tcccgtgtga agagaatata
      841 ttcattattt tggcgtgctt tagctaatct ttgagcaata cgttctgcca attgatctga
      901 ctctggaata taaaattcgc tgtttggatc aagaatatga ttttgcatat caataataac
      961 taacattttc tttcctccta cattcatatc gtcattttat tctttttaat agaagttttt
     1021 taaaatataa gcaacaccag cttcttcatt cgtcagtgtt acttggtttg caatttcttt
     1081 tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg ctgtaattca acatagcaat
     1141 gtcgttttct tgatcgccaa aagccatgat gtcactcgat tcgattccaa ggtaatccgc
     1201 cagaaaaaca agtgaatgag ctttagtgat acctgtaggc gtgatttcta agaaatgcgg
     1261 atcagagaat actgattgga taccatctgc ttgcagatct ctttgtagct tctgtagttt
     1321 ttcttcactc ttatctgtta atgctaattt aagatagcta agagaaggat cttccaacat
     1381 atttaaaatt tgatcaaaag aatggttctg taaattgaaa tgttcataat aagggtcatc
     1441 tttgactaga tttgattcat cgaatgtcag ctgatcatct tgggtttctc ggctagcaat
     1501 gatggatatt ttcgcttctt gagcatagaa gaaggctttt ctcagtgtat cgctatctat
     1561 ttttgaacgt ctgagaactt tcgccatttt tccatccttc atttcagcaa tcagtgaacc
     1621 attggaagaa atcaaatagc caccgattcc taattcggaa aaaatatctt tagcagaaat
     1681 gctgttcctt ccggtagcga cggttacgat tccgccattt tcatcaaatt tccgaagtgc
     1741 ttggatattt tcttctggta tctttccatt tcgatcaagc aaggtaccgt ctaaatcaat
     1801 cgctgctagt ttcattttat cttcctactt tctttttaca tatctatttt cctgttacct
     1861 taagattaaa tgagaattta aaaaaatgaa actaacttgc tttgtcatta tgaatttttt
     1921 caaaaaacat tcttaagaaa aaggtggcta tatatagtag tttttggtca atacctttga
     1981 ataaaaagcc atgaaaaacg aatagttagc gcttaccgat gcgttttgtg ataaaaaaat
     2041 tttaaaatat tcaatgaaaa caaagcatat attttgcttt aaaaccaaat gaggaatatt
     2101 ctagatgtag aacaggttag aaaaagatta gaaaaaggag tgattttgat ggagaagaga
     2161 tacggcgtag ttcctgtggt aactgcttca gacgaaaatt atgctcctta cttgagcgtg
     2221 atgatcgcaa ctgcattaga aaattgcaat aaaacaagac gcataaaatt ttatgtgatt
     2281 gacgatggtc tatcagaata tagtaaagaa ggattggaag aaacggtaaa taaatattca
     2341 agtaatgcaa gtatccaatt cctgacagtg gaaaaagata tctacgaaga cttcctagtc
     2401 agtgaccata tcacaactac cgcttactta agaatttctt taccaaactt attagctaaa
     2461 gaggattata agaaagtcct ttacttagat tcagatgtgt tagtactaga cgatatcgta
     2521 aaactatatg atgagccgtt aaatggaaaa acaatcggcg ctattatcga tccaggccaa
     2581 gtgaaagctt tggaaagatt aggaatcgat tccgatgact tgtacttcaa ttcaggagtg
     2641 atggtgattg acattgatca atggaataaa aaagaaatta cagaaaaaac tatccattac
     2701 ctcagtgaaa atggcgatcg aatcatctat cacgaccaag atgctttgaa tgctgtactt
     2761 tatgaagatt gggaacaact tcatccaaaa tggaacatgc agacttcgct gatttttgaa
     2821 cgtcatccag caccaaatga aaaatatgaa cgtcagtata aagaaggaaa tgaaaaacct
     2881 tcgatcgttc actttacagg acatgataaa ccttggaata cgttgaaaga tcatccgtat
     2941 accaatttat acttaaaaaa attagcacac agtactctaa cgaaagtagg cgagatcaat
     3001 gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca aaattcgtac cacatttagc
     3061 tgcattattt gtctcagtat tagataattg caacccgtct aaatttgttc ggttctatgt
     3121 gattgacgat gatatcgatt ttgaaagtaa acagctttta cgcttctcag tgaaaaacgc
     3181 acgaatgaac tcagatgtgg aattcttgaa aatcaataaa gaattcttta caaatgtggt
     3241 aatcagcgat cgtattccag aaacagctta ttatcgtatt gcgattccgg aattgttccg
     3301 cggcacagaa gttgaacgta tcttatatat ggattgcgac atgatcgctt tacaagatat
     3361 ctctaaatta tggcgtcttg acttcggtga ttcaatcgta gcagctgttg aagacgctgg
     3421 gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa tcaatgcgtt atttcaactc
     3481 aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa aatattacgc aaaaagtatt
     3541 agatttcatc gaacataatc cagaaaaatt acgattccat gaccaagatg cattaaatgc
     3601 tatcttacat gaccgttggt taccacttca tccgcgttgg aatgcacaag gctatatcat
     3661 ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt gaatacgaag aaactcgcaa
     3721 caatccttac attatccatt tttcaggaca tgtgaaaccg tggagcaagg attttgaagg
     3781 gccaacgaag aaatattacg aaaaatatgc agggatgacg gctttccgtt gtgtagctaa
     3841 attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa acagatgtag ttgttaaata
     3901 atagaagaca acaactgaag agggggagta ggaatggaaa ttacaatgtc taaaaatgca
     3961 gtagagacgt taattgaaaa ggttggggaa aatacaaaaa tcgcactcgc gcttatcaat
     4021 gattccgatc catttctaag ggacaaaggt gcttttgcaa aaggcagctt ttttcaaatc
     4081 attccttttg tttcggaatt tggagaatat gcgactaaaa tcgagcatcc attattggac
     4141 atctatacat ctaaattaga gcaaaattat ttcggtaaac gattgaacat ggacttcaac
     4201 aaacagcttg acagcttttc attagaaaat gaaatcgcag tactcgatta taatatcaaa
     4261 ttaaagaact gcttcttcag ctaatagttt cgagaaagtc caaaaaggag gtatacattg
     4321 agatactact ttgtggatga agaaaagaat gtaatagaaa cagatgaaaa aaaatataat
     4381 tggctcgtac ttgatagtgc aaagcccgaa gagattgagc aagcaatcga agaattcgag
     4441 cttcctgatg atattttcgt aggaaccgaa tatccggaag aagtttctcg gatggagcgc
     4501 ctttatgaga cgaaactaga gcatccattt tctttggtag tgattaatct agatcagtca
     4561 gataatcgta tcgaaaaaaa attaacgcca atatcttttg tactttccga taatctcttg
     4621 attacttgta tcgatagaaa aaccgaattt gtggatcggc tgctgacaaa gcatggaaat
     4681 catttaaact cgtttgaaaa gatcatcacg tatacattat tagatattta cacccattac
     4741 gtgaaagaac taagagagat gaaaaagcga attgacgctt tggataaagc agctcgtaaa
     4801 acaacggaaa atgaagaact gtataaacag gcagatcttg aaagagacat cgtatatatc
     4861 gatcatacct taagagatca acgggaaaca atggatcaat tatggaattc tgaaactttc
     4921 atcaaacgtt tagacgatga acagctactc tatgatgtcc atttgagaca gcgacaaaca
     4981 gaaaaaatga tcgagatcta tcgagattta ttagagagta ttggtgatct attcaacggg
     5041 atgatggaca ataatctaaa tcatatcatg aaatatctag attcagctgc attaatcatt
     5101 tccgttccgg cgttgttcgc agggatttgg ggaatgaata caggaggatt accgggtaaa
     5161 agttctgctc taggctttat actcgtagtc tttggctctt tgatagcagc agtagtttta
     5221 ggttaccatt tataccggaa agattataca aattaaagaa tctatttaaa acaggtatca
     5281 aacaaagaaa tttgttttgg caatacaatt taaaaactag gaggaataca gcaatgacag
     5341 aaccaaaatt aatcgacccg cgaaacttgt accatacgga gaaatttcct aaacaagatc
     5401 aggatacacc agctttacag cagaatatga ttcctgttcc tgattgtgga gaagaatcct
     5461 atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat cactggtgga gattcaggga
     5521 tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc agatatcgct cttcaattct
     5581 tcccaggaga agaaaaagat gcagaggaag tagcaaaata cgtgaaagat gcaggacgta
     5641 agattgtctt actacctttt gatcttcgtg acgaacaagc acctaaagaa atcatagata
     5701 aagccgtgag tgaacttggc gggctagata cgatggtact aaacgcagga cagcaaattt
     5761 cttgtcagtc tattgctgag ttaccacttg agcaagtcaa agacacattt atgataaaca
     5821 tcatcgctat gtttgcttta gtgaaagaag ctgttccgca tatcccagca ggaggagcaa
     5881 tcgtaacaac aacttctgtt caagcattca atccaagcga acatttatta gattacgcag
     5941 caacaaaagc ttcaatcgct aactttacga tcggtttagc aaaacagctt gcacctaaag
     6001 gaatccgtgt aaatggtgta gcacctggtc caatctggac accattacaa ctagacgaag
     6061 gacaaccttc tgattcgatc cctgaatttg gtcagcaaag tttactagaa cgtgcaggtc
     6121 agccaggaga attagcacca gtttatgttt tcttagcatc gaataaagca agttatgtta
     6181 cagcccaaat ttacggagta actggtggag aagcgatcaa cttataagaa gttgatcgtt
     6241 tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa aaacgatcgg agtgatcgga
     6301 acattacttt tgctatctgt gcttttgttt gcgatactat taagtgcaac ctatccattg
     6361 ccttttcagc tagagaagtt tcgattcttt tccatcacta attcatacgt gcaacaatat
     6421 gtattttggc ttgccgttgc atttgctatt ttgacaatta tcacgttact tgttttcctg
     6481 ttttatccaa aaacaatcgg aaactttcta ctgaaacatg gtgatgggga gttgacgttg
     6541 gataaaaaag caattgaagg aatggttcgt tctcacttgc atgaagatga attcatccat
     6601 tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg ccgtcaatgt aaaaggggag
     6661 ttgaaacgaa cttcagcact cattggtaaa acaggaacat tgatgaaaga aatcgaaaat
     6721 gaagtacaac acatattggg aacaaaagag ccagtgaaag tatcggtgaa atacacaggc
     6781 tttgaagaac cagctaaacg aagcaatgac cgcaaacgag tagaataggg ggggaccaaa
     6841 aatgaaagaa ctattttcga catacaagct ccctatcatc tttggggtac ttggattgat
     6901 attagccgtt ttatggatca ccgtgggctt tttcaagacc ttattgatct tgatcatggc
     6961 agcgatcggc gtcgctatcg gtttttatct gaaacaaacg aaaatcttag atcactattt
     7021 taaatcttag gaggaaacat ccatgaataa caataacaaa aataataaca ataaaatgaa
     7081 caaccaaaaa ccagtgtctg cacatccaga cccaacgaca ccaaaccaat caaatggtgt
     7141 gaacgatgaa aagaacaaaa cagcaccagt atctgcacat ccagatccag tagtccctaa
     7201 cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa aagcatgcac ctcatcatcc
     7261 aggaactcca gaatctaaag ttccagaaca acatgatgca atcgatcctt ctaaacctgt
     7321 ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa gaaaaactta gttctgacca
     7381 cacaaacgga caaggaaaac ttggttctga tcatacaaat aaccaaggaa agcatgattc
     7441 tgaacaggaa gattcaatgc gcggtgagct gaattatgaa gataaagttg tgcaaaaaat
     7501 catcggaatc gcaattgaac aagtagacgg tttattatct gcaaacggtg gtttcttctc
     7561 taatgtggca ggaaaacttg tgaatacaga taatgtaacg gctgggatcg aaacagaagt
     7621 cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg gaatatggca aagatatcga
     7681 aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa gtaaaaaata tgacacattt
     7741 agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa acaaaagaag aatttgaaaa
     7801 agatcaagaa acggtgcaag acaaagtaac tgacgcagcg aaaaaaaccg gtgaatttgc
     7861 ttcgaatcaa acagataaag taaaatcagc agctggaagc ggcgcacaaa aagtaaaaga
     7921 aaatacagaa ccacgggttc agtaataagg aagtaaaaca ttaggaggaa cgaaacatgg
     7981 gatttatttg gtcacttatc gtcggaggaa ttatcggagc aattgcagga gcaatcacga
     8041 ataaaggttc ttcgatgggg attattgcaa atgtcgtagc aggtttagtt ggatcagcac
     8101 ttggtcaagc attattaggt tcttggggac caagtattgc aggaatggca atcgtgccat
     8161 cattgattgg tgccatcatt ttagtactaa tcgtatcatt ctttgctcga aaactgtaaa
     8221 aagactttta aaaagaggtc gtgaaaaagc tgttcttcat caagtaataa gaacagccaa
     8281 acaaaaatag cttctcatat ttttcatttg gttgggcata ttatcgaaga tgcaagcttt
     8341 tgaacactgt ttatacggaa taagaggctg tgacaagact tttgtcacag cctcttattt
     8401 atgcgggcaa attcccaatt agatttttaa aagtttttcc ttaaatgtgt ctttattgat
     8461 acagagaagc ttctttaata aaacaatgcc tccctaaatt ttcttgagat aggaaaggtg
     8521 aacatacaaa ataatacgac cactttgaaa acccagatga tccacaaatg gatcgtatga
     8581 tactgatgaa gtaaaaagca atggatcaga aactcaaaga gattgaaaaa gacaaggaag
     8641 aaataatatc tcttttttac tcttgtctgt tttagccaat aatagctcgt aaagtaatct
     8701 agacaaacaa atagaagtaa acaaagtttc gtaagagcag caatcgtatc atgttgctct
     8761 gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa tatagatcac gagtaatgaa
     8821 agaaaaaagt aaacaataaa tggcatacta ttcctcctaa ttgtgtgagt tcgccctcat
     8881 tttaaaataa cgatatttgt ttgtgaagct ttttc
//
LOCUS       DADVXB010000117         8832 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.120, whole genome shotgun sequence.
ACCESSION   DADVXB010000117 DADVXB010000000
VERSION     DADVXB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.120"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            8..307
                     /locus_tag="KB902_002185"
     CDS             8..307
                     /locus_tag="KB902_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808971.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(404..838)
                     /locus_tag="KB902_002186"
     CDS             complement(404..838)
                     /locus_tag="KB902_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6808972.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1070..1780)
                     /locus_tag="KB902_002187"
     CDS             complement(1070..1780)
                     /locus_tag="KB902_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6808973.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1770..2630)
                     /locus_tag="KB902_002188"
     CDS             complement(1770..2630)
                     /locus_tag="KB902_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBB6808974.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2635..3273)
                     /locus_tag="KB902_002189"
     CDS             complement(2635..3273)
                     /locus_tag="KB902_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBB6808975.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3288..3587)
                     /locus_tag="KB902_002190"
     CDS             complement(3288..3587)
                     /locus_tag="KB902_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6808976.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3630..5105)
                     /locus_tag="KB902_002191"
     CDS             complement(3630..5105)
                     /locus_tag="KB902_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6808977.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5125..5586)
                     /locus_tag="KB902_002192"
     CDS             complement(5125..5586)
                     /locus_tag="KB902_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6808978.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5604..6671)
                     /gene="ulaG"
                     /locus_tag="KB902_002193"
     CDS             complement(5604..6671)
                     /gene="ulaG"
                     /locus_tag="KB902_002193"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBB6808979.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6889..7659
                     /locus_tag="KB902_002194"
     CDS             6889..7659
                     /locus_tag="KB902_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6808980.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7932..8759)
                     /locus_tag="KB902_002195"
     CDS             complement(7932..8759)
                     /locus_tag="KB902_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6808981.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2683 a         1861 c         1382 g         2906 t
ORIGIN      
        1 ataaaacatg gattatactg ttgaatttga cagtgaacta cttaagcaat ttccacaaga
       61 agaacatttc atgtataaag aagcaatttc ccacaaagtg acagagtatt tggagcataa
      121 tttttttcgt ataaagccag tgcgtactcg ttcggcaaaa ggaatatacg agatgaaagt
      181 caaaattaat aaaaaaaatt atcgcatagc atttgcttta aaaaaaaatc atgtgttcat
      241 tttttatatt agttcgaatt tgcaaaaaat tgtatttgat aaagaggtga gtaaaaaaat
      301 aaaatagctg agcattggag gatagattga gtgatactaa gtctatcctc ttgtttttct
      361 aaagaactaa gctagaattt tttcttttgt acgttattat atgttatttg tcattaccaa
      421 aaagcacctt ttttcttcta gtatctatga cataagaaat accacccatt tcctttactt
      481 gaacaaatcc tactgattca taaaattttt ttgttttctc agtatcatct gtcaataatt
      541 cgatttggac tggtccataa ctagtgatct tctccaaagc ttcattcaaa agcactttgc
      601 ctattccttg gcgctgatac ctcggatgaa tgaggatatc ttgaataaat gcgatcgtcg
      661 caaaatcagt gatccaacga acgattccga taatcttccc ttccccatta cgctttatca
      721 gagattcaga ttgttcaaat gctctagcta accttgcagt gtcttttgtg taattcgtcc
      781 aaccaacgct cttatataat tcagaaatct catcgatcat aagggaatca atattcattt
      841 ttttcttcct ttcttataca attctccctc taataataca gttctttgac tatttaatct
      901 atcacatata actctcctgt aaagattctc tcgattcctt aaaattcctc tttcctttta
      961 gaatgcatac tttttgataa ataaaaaggt tgtgataaat tttcttcaca acctctgttt
     1021 ctctctatca agtgttatct tttaattttc tacccttacc ctagcatctc tattgcccgt
     1081 agtatgcata ctttccatgt ttgcgaaaat aatgtttatc tagtaaatat tgcgggattt
     1141 cacatatatt ggggttgatc agctcgtttt ctttggccat cagacaaatt tcatctaaga
     1201 tcaaactgtt ttctactgct ttcataggtg aatcccccca tgtgaacggt ccatgtccat
     1261 agacaagtac tccagggact tcgtttggat ctaattttct ttccttaaac gtctcgacaa
     1321 tcacattccc tgtatgaact tcgtaagctt ctcttacttc ttctttcgtt aattggcgtg
     1381 tacaaggaac cttaccataa aaagcatcag catgagtcgt gccataagct ggcaaatcgc
     1441 gtcctgcttg cgcccacatg acggagtgcg tggaatgagt atgagtaata gcagttatat
     1501 cttcaaaagt ttgatacaaa acaacatgtg tggggagatc tgaagatggt tttaagctat
     1561 cttcttctat tatatttccc gacaaatctg ttaccaccat ttgatctgct tgcatgcatt
     1621 catatctgac accgcttggc ttaatgacga tgactcctag ctcacggtcc acttcactca
     1681 cattgcccca agtcaatttg actaatccgt atcgcggcaa tgccagattt gcttcaagga
     1741 cacgttgctt cattgctgca attttttctt cacaagacat catagccagc ctccttcaat
     1801 ttagaactta agtagtcttt tgcctgctgg atttctcttc gaaagtcttg gcttttttca
     1861 ctccacattt caatcagaaa tgttccatca taatctagac gtttcaaatg tcttaataat
     1921 ccaagaaaat caacacaacc gctaccaaaa ggaacatcac gaaactggcc tgaatattct
     1981 tttgttacag ggtaagtatc ttttaagtgg atagcagtga tataatcgat ccctttctca
     2041 agttctcgag ccggattatt ttccggccat gcggacaaat tgcctaggtc tggatatact
     2101 tgtagaaaag gtgaatgaat ctgttctttg atttctaaaa attttgaaat ggagttcata
     2161 aatggatcat ccatgatttc cacggaaaga atgatgccat atttagaagc ttcctttacg
     2221 ctttctttta ttccttcgat aaagtcttct ctggaattca ttgatttctc ttcataataa
     2281 acatcgtatc cagctatttg gattactttg acgcttagat tatgcgccaa atggattgct
     2341 tttttcatta gttgtttcgc tgcttttttc ttttctggat cagcagaacc aaacggaaat
     2401 cgccgatgcg cacttaaaca aatcgaatgg atacgtacac cggagctgaa catctcttct
     2461 ctcagctcag ctatcttttc ttcagaccaa tctaatcgtg ctaaccgctc atccgtctca
     2521 tcaatcgaca tctcgataaa atcgaagtcc atttctttta caagggaaaa acgttctttc
     2581 catgaaatat ctttgggtaa cgctttttca taaatcccaa tttgagccat ttccttaccc
     2641 ccagatacga atgatctcat ctttgaagtt ttgtgcggcc ttcatcggat catttgctgc
     2701 tgtaatacca cgaccagtga taaaggtata cacatcgatc ccttcaaata agtgtaatgt
     2761 gtgtggattt aatccaccag ttacagaaac attaaagcct agttcaatca gttttttgat
     2821 cttcgataaa tctttttcac cccaagtttc accagataac agcgcatcac ggctttgatg
     2881 gtagattacc tgccggatac cgatgttatg ccaatccatg gcttgttcaa aagtccaatt
     2941 gccgtagagt tctacttgca attcacctat ttctttttgt gctgcctcca tagttggaat
     3001 cgttgcacaa caaatgactg tcatccagtc tgctcctgct tttgcaacat tactcgccac
     3061 tgttcctcca gcgtctgcac atttcgtatc agcgactagt tttttatctg ggaacatact
     3121 gcgaatacag cgaatcgctt tttgtccttc ctgtaagcaa agaattgtgc ccacttcaat
     3181 aatatctact acatcaccaa ctttcataac atctcctaat gcatgttcta agtcattgtg
     3241 atctaacgca atttgcaaat tcggcctgct catcttagtt ccttccttta cttgtttttt
     3301 tggtaccact ttgtttcagc aaatttttca ctgatttctt tgactgacat cacatttttg
     3361 ataccgataa ctgtaactcc ttttttctct gcctgagtaa acatattcaa aaaattgact
     3421 ggcgtaaaaa ctacatcgta ttggccagct gaactttttc cctctgaaat ggcacaatga
     3481 tggattttgg taattggtac gtttagttct ttcattgctt tttccacact tctcatcatc
     3541 atcaagcttg ttcctgatcc atttgcacac gatactaaaa ttctcatctt aatccctcca
     3601 ttatgagtgt tgtctaatca gattttcttt tatactctct gcttttctgc atatgtgtca
     3661 tagtcttcta caatcaaaaa ataaccatca ggatttttcc gatattgtaa ctgcggaata
     3721 gccaataaac caatgacaac tacggcataa cctaggactt tcatgattac tgtaaacaat
     3781 ggccaagctg ttgcccagtc gaacatcccg atataaccac cgtatgttga catcccaatc
     3841 catgtagcga ataatgctga accgcctact tgtatgattc ctgaaagaaa cgggaacagg
     3901 caagcggctt tgaatccacc tcggttattg gcataaactg ctataacggc attatcaaag
     3961 aacaacggaa tgaaaccggc tatgacgatc gttggtgatt tcaataaaat cagtaaacca
     4021 atcatcaaaa actgtcccaa agcaccaaac aagaacccaa tcgttaccgc atttggcgaa
     4081 ccaaagccaa aagtagcagc tacgtcaatt cctggaacag ctcctggtaa aatcgtgttt
     4141 gagattcctt ggaaagattg agttagttca tcgacgaatg tccgaacacc taattgcaag
     4201 atcgccagat ataccgcaaa atttaaagaa gtcgtcataa tgtagaataa gaaactctgc
     4261 ccttcttgca tgaattgcgc ttgaatcaaa taatctttgc ctagtacaat cagaatgatc
     4321 ccaaagaaaa atagcatgag taacgaagta gcaaccatat tctcattgaa aatcgacaag
     4381 aatcctggta atttgatatc ttcaattttt ttgtcttgct tgattgatct atttttcttt
     4441 tcatcccgct ttttcatcca ctcagctaat tttgcaaata taaagattcc gaacatttgc
     4501 tgatgtgcca ctgcaaatcc ggcaccttct gtcaattcct gcgtgattcc tactgttaag
     4561 ttagaagcta ctgcccaata acaacctaaa atcagtccca taaaaatcaa tacttgtatc
     4621 ctacctagat caggaaagca aaacagtaaa atccaaaaag cggtagctgc ttgttgaacc
     4681 tgaacgtttc cggtagtgaa aacggaacgc agtttcgtat atttctgaaa acggactaat
     4741 aagatattta aaacaaatgc aatcagtaat aaaatcatca catctccaaa ggtacggcca
     4801 aatgtctcca ttaatccagc atccacagca ttttgtccaa aataaggatc tgtaaccatg
     4861 gcatccaaat tgaaccgttc ctttagtcca accaagattg gccgaaaatt attgaccaaa
     4921 ccaccagagc caacagtcaa aataaagtaa ccgaccgttg cctttaagaa tccagcgatg
     4981 cattcatgaa gcgggcgttt cagcaaaata tagcctaata acacgataaa accaatcagg
     5041 tatgctggct gcgtcaagat atttgttgca aaatacgtcc aaatgcttaa caaaaattcc
     5101 cccatctttt ttctcctcta tcaattaatt atattctgcc atcacaactt ggtaatcatc
     5161 gatggagttc gtagagatga gacgctcaac caatccatct gtcattaata attcggataa
     5221 tttttggata ttttctagat gttcttctgg atcttttgct gcgagtgtaa aaaacaaact
     5281 agccgttttc tcctcattct ccccttcact ttcaaaacgg attggctgtt tcaacttggt
     5341 aaatgaaata gctgttccaa aaacaccatc acttttttct gaagaatgcg gcattgctac
     5401 ttgaggtgcg atcacaatat aaggaccgta tttttctaca caatggatga tctcctccac
     5461 atacgtttca tcaataattt ccttatcgat caatacaaga cagctttcgg cgatagcttc
     5521 acgccaatcc gtgatttctt tatctgggta atgaatcaat tgatggtcaa aaaagtattt
     5581 cagcaagaaa ctccccttct ttcttataaa aacgacggaa acggtgtatc attttcaatc
     5641 gagaagacat cttcaaatcc tcgataaaaa ttaaactcaa gatcatcttt gtttgtcgga
     5701 tagatgaatt tcccgcctac ttgccagata taaggtttaa atccatactt caggcgatcc
     5761 tttttgaatt tccaaatttc agtgatctct tttggatcag ccataaaatt agaccaaata
     5821 tcgtagtgga caggaatcac tacttttgca ttcaatgact ccgccatgcg cagcatatca
     5881 acagaagtaa ctttgtctgt tatccctcgt gggttttcac cataggcccc taaacagaca
     5941 tcgattttgt gttcattacc atgtttggca aataaattgg agtaatgtga atctcctgca
     6001 tgataaagat tccctcctga tgtttcgaat aaatagttta ctgcaatttg atccatctcc
     6061 tgaggcattt ttccttttaa tacctcttct ggatcttcac aagtgaccaa cgctgtccga
     6121 tcaaacgctt ctaaagctac tacattgatg tctttgattt tgactgcatc acctggcttt
     6181 actgtaatcg ttttttcttc aggaattccc catttttgcc acgtgcgaac cacttctttt
     6241 ggcccaatga atgttgcttc aggacaattt tgatgaactg ctgcggctgt atggatatct
     6301 agatgatcgg aatggatatg tgtaacgatt aaagcgtcta cattttttat cgcaaaagga
     6361 tcgattacga aaggctgagt acgtaaatta ggctgcatat tttgaacgcc actcatacgc
     6421 atcatctgat ggcctttttt catcatgcca ttcccatgac tacgttttcc cgtcccacac
     6481 catagatcac ataaaatatt cgttccttca tgacttttca gccaaattcc cgtacagccc
     6541 agccaccaca tagcaaaagt tccaggatcc actacttctg tttcgatttc ttcattcaag
     6601 tatgtgcccc actcaggaaa tgtttctact aaccactttt cttttgttac ttcattgaca
     6661 gttttactca tttgcttgct ccccccatat cgttgttcca acttacaagt aaatattaat
     6721 gtgtatcagc atccatgaaa acccttttat atgaccgttt gttttttata tgattttctt
     6781 tcagtaatca atgattgttt cagtataata aagacagata tgaatgttta aatgaacaac
     6841 tagtcaaata aatccatgga tcaagatgtc cctcaggagg caaaagtcat gaaaaactca
     6901 cttgtcaata ttgaaaaacg tcaaaaagaa attttggaac tgcttcagca gactgaacaa
     6961 ctatcaactt tcgaattagc tgaatccctt gatgtatcta ttagtacgat acgaagagat
     7021 ttaaatttat tagaagaaaa aaacgagatc atacgcaatt acggttattg ttcttataat
     7081 tacaaaaacc agactgattt tgatcaatct ggtcctgaaa ggattaaaca agcgattgcc
     7141 agagaagcta gtaaatacat taacgattat gatacgctgt ttatcaattc tagctcgact
     7201 gcgttgaaaa cactggattt tcttcaatct aaccatttga cagtcattac aaacaacgtg
     7261 aaaatcaatt actctccgca caaagataat tgtagttata ttttaactgg tggagagatg
     7321 cgctttccaa aagaagcact agtgggcgac atcgcattaa atacgatttc ttcagtcaat
     7381 gcagacattt gtatcattgg ctgtagcgga gtcgatgtag tacatggggt cacaacaaag
     7441 atattaaatg aatcaacgat caacgaaatg atggtcaaca agacaatcaa atgtaagatt
     7501 ttagtcgctg atcatcgaaa aatcggactg acatcaaagt tcaagattgc tgatatttca
     7561 gtctttgatt atttgatcac tgataaattt tgttctgaaa aagtattaga ggagatcaga
     7621 aatacgggga taaaaaccat tcaagtagat tcattttaag aaccaggacg taaatatgta
     7681 aataggatta tcaaaaaaat gaataacaaa tttatcgata aatgaaaaac acgctacgct
     7741 caaattgata aaggaatccc aagatgtatc catccaatcg ataccatcat aatctattgc
     7801 ttcttttata accgttatat gttgcctaaa taggaatcaa acaatatcga aaaaaggagg
     7861 tatgacaaaa gtcacacctc cttttttcga ataaacggta ttcaaatcag aacactgatt
     7921 tcacaaccac tttatttcag gtcgttttca atcaccttta ccgcgtaatc atttccgttg
     7981 aaacgcgcta ttttttttgc gtccatatat ctttctaaat aatcatcttc tcctaattgc
     8041 ttatggcaag aagcaatttc ataaagcaag tattccaatg cataagtcga tttatgtttc
     8101 ttattatact caataccctt ctcacataat tggattgctt tatcataatc ctcgatttta
     8161 cggtaatagg tggcgatatc ataatataca atgcagacca tcagattatc aaaatcagtc
     8221 tcactcaata ttttaagtgt acgctccaca taaactttcg caaaatctaa ttctcctttt
     8281 gacaagtaga tcattgccac gtttgcagct gcttgtaagt gatggatatc tgtttcggtc
     8341 gtttgttcca acacttgatt aaaataaaat aatgctgcat ctggtttttt cgcataaaga
     8401 tgatcaagca gtccttgata aaataaaatt tgatttaaaa gatcagaatt acttactttt
     8461 tcctgatcga tcgtttgtaa aattttataa gattcttggt attttgatac agaattcaat
     8521 gattgaatct catttatttt tttcctgatt ttgtcttctt ctgtttctac taatatatcg
     8581 gagatctcga cattcagctt tttgcaaagc gcacttaaga tattgatgcc tggcgacata
     8641 ttcttgtttt cgatattgct gacagttgct tgttcacaaa tgccttctgc taattgtact
     8701 tgtgttaacc cctttttctt tcggtattct tttagtaatg ctccatctac tttaatcaaa
     8761 acaatttcct tccctttaaa aaattatttc tcctttatat catacacaaa aaaaagttct
     8821 aaacaaccaa aa
//
LOCUS       DADVXB010000118         8820 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.121, whole genome shotgun sequence.
ACCESSION   DADVXB010000118 DADVXB010000000
VERSION     DADVXB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.121"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            106..1167
                     /locus_tag="KB902_002196"
     CDS             106..1167
                     /locus_tag="KB902_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6808982.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            1170..2066
                     /gene="murQ"
                     /locus_tag="KB902_002197"
     CDS             1170..2066
                     /gene="murQ"
                     /locus_tag="KB902_002197"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6808983.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            2080..4062
                     /locus_tag="KB902_002198"
     CDS             2080..4062
                     /locus_tag="KB902_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6808984.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(4127..4573)
                     /gene="nrdI"
                     /locus_tag="KB902_002199"
     CDS             complement(4127..4573)
                     /gene="nrdI"
                     /locus_tag="KB902_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6808985.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            4784..6208
                     /locus_tag="KB902_002200"
     CDS             4784..6208
                     /locus_tag="KB902_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6808986.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(6389..7162)
                     /locus_tag="KB902_002201"
     CDS             complement(6389..7162)
                     /locus_tag="KB902_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6808987.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(7159..8064)
                     /locus_tag="KB902_002202"
     CDS             complement(7159..8064)
                     /locus_tag="KB902_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6808988.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(8218..8538)
                     /locus_tag="KB902_002203"
     CDS             complement(8218..8538)
                     /locus_tag="KB902_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6808989.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         2775 a         1578 c         1877 g         2590 t
ORIGIN      
        1 tagaaatgaa atttaattat tttaataaaa gtattgaaat tttgtttctt tagatatata
       61 ctctagtcat agaaatgaag acggatacag aaaaagaggg ataatatgtt tggcttttca
      121 atatttatga acgattcttt gtcagaagag aagaaacagt atatccgcca aatggcatcc
      181 aatggctttg tcggtatttt cacttccatg catataccag aagatgatgt ttcggcatat
      241 caaaagcgat tgatcgaact aggaagcgaa gcgaaaaaga ataaactaga attgatggtc
      301 gatatttcag gagaggcatt ggaacgagcg ggtttttcat tagaagatct aacgcctttg
      361 aaagcaattg gtgtaacagg tttaagaatg gattatcata tttccaatca gcagattgcc
      421 gactggtcac atcaattgaa aatcagtttg aatgctagca cgatcacgcc taaagatatc
      481 gatgaattga aagaagcaga agctgatttc tcacagattg aagcttggca taattattat
      541 ccacgtcccg aaacagggct ggacaaagaa tggtatcaga aaaaaaatca atggctcaaa
      601 attcaaggtc tccttgtcca aggttttgta ccaggagata cagagttgag aggcccacta
      661 tatcaaggat tgccaacttt ggaagaacat cgagggatcc atcctcttgc aggcgctcta
      721 gatctattag caagtaacac ggatattgtt tacatcggag atgcaggtct gtcagaaaac
      781 gttcaggagc aatttgcttc tttccaaaaa gaacagacag tcttgctcca tacggaacct
      841 gtagatgaag aattttacga atatatatta gggaagcata cgaatcggca agacgatgca
      901 agagatgtca tacgaagcgt agatgcacgt tttcgagaga ttccgcctat cccagcaaga
      961 aatacagcta cgcgtatgaa agggtctatt actttagata acgaaaagta tttgcgctat
     1021 atgggtgaga tccaattaac caaatatgat ttgccagcgg atgaaaaagt gaatgtagta
     1081 gctaaagtta tcaaagaaga gctaccattg atcaaccaaa tcaaagctgg tatgaactat
     1141 caatttataa gaaaagaagg aagataaaaa tgagcaaaat caatttagag aacctaacaa
     1201 cggaacgcag aaaccaagaa acttttggat tagatgagat gagtatttct caagccgttc
     1261 aactaatgaa caaagaagat cagaaagtgg ccgctgcggt tgaaaaagaa ctgacaagta
     1321 tcgaaccagt gattgctaac acgattgagt cctttaaaaa aggtggacgt ctgatttata
     1381 tgggagccgg aacaagtgga agactaggtg tgttagatgc tgctgaatgc gtaccgacat
     1441 tcggtgtaga accggaaatg gtcataggtc taattgctgg tggagaagaa gcaatgactg
     1501 tagctgtcga aggggccgaa gattcttatg agctagggca agaagatcta atcaagctga
     1561 atttgacaaa aaatgatata gttattggta tcgcagctag cggtcgtaca ccatatgtga
     1621 tcggtggatt agattacgca aaatcgatcg gtgctgtcac aggaacgatt tcttgcaata
     1681 aacaagccga aatcagtaaa cacgcggatt tcccaatcga agtcgatgca ggtccagaat
     1741 ttttgacagg ctctactcga ttgaagtcag gaacagcaca aaaacttatc ttgaatatga
     1801 tttctactat cagtatgatt ggtataggta aagtattcaa taacttgatg gtcgatgtca
     1861 aaccaacaaa tgaaaaacta atcgaacgct caaaacgaat catcatgcaa gcgacagaag
     1921 ctgattacga aacagctgaa aagtactttg aagaagcaga tcaaaatgtt aagctggcta
     1981 tcgtcatgat tttgacaaat agtgataaag aggaagctca agcaaaatta gctgaagcaa
     2041 acggatttgt aaaagggacc ttatgagggg gaaaagacca tggcaaaaaa cgaactgact
     2101 ttggaagaac tggcaaaaca aatttataaa ggggcaggcg gcatgggcaa tgtagaaagc
     2161 attgtccact gcatgactcg tgtgcgtatg aagatcatca atgatgatct tgtaaatgtc
     2221 tctgaattaa aagcgattcc aggagtgctt ggtgtagtag aagatgaaca gcttcaagtc
     2281 atcatcggac ctgggaaagt gaacaaagta gcacagcaaa tggttgattt ggcaggcgtg
     2341 aaattaggag aaaaactttc ttctgtaagt acagctacag caaattcatc agcatctgga
     2401 aaagaccgtg taaacgaacg ggcacaagaa atgaaagcgg cacaaaaatc gaaacaaaaa
     2461 ccatctaaaa tcaaatcggt attaaaagac atttctaata tctttgtgcc aatgattcct
     2521 gcatttgtcg gtactgggat cgtggcaggg attgccgcag ttttagcaaa cttagtcaca
     2581 gccggaacac ttgatgcagc aacatggcaa caatatatcg atgtgatgaa catcttgaaa
     2641 aacgggatgt ttagctacct agttatctat acaggtatca atgctgcaca agtttttggt
     2701 gcaacaccaa ctcttggtgg agttatcggg gccgttgtga tgctgacagg gatgaatccg
     2761 gaagcaccac tgaaaaactt atttactggt gaagctcttg cagctggaca aggtgggatc
     2821 ctaggtgtca tcttcgctgt ttggctattg tcaatcgttg agaaaaaact gcataaagta
     2881 gtacctgatg cggtagatat catcgttaca ccaactcttt cattgattgc catcggtctg
     2941 attgaaattt tcttcatcat gcctttagca ggtttcattt ctgatggcat ggtcggtggg
     3001 atcaactggg tacttggcgt tggtggagca tttgccggct tcgttctagg cacattattc
     3061 ttgccgatgg ttatgttcgg actgcatcaa attttgactc caatccatgt gcaaatgatt
     3121 gatgaaactg gtcgtacgct attgcttcca attcttgcga tggctggtgc aggacaagtg
     3181 ggtgcagcat tggcattatg gattcgctgc aaaaaagata aagaattaac agaaatgatc
     3241 aaaggagctt taccagtcgg gatcctagga atcggcgaac cattgattta cggagtaaca
     3301 ttacctctag gacgcccatt tattactgct tgtatcggtg gaggtatcgg cggggcagtg
     3361 atcggaatga tcggaaatgt cggggctatc gctattggac cttcaggagc cgctttgatc
     3421 ccattgatct ctgacggtaa atggttaggc tacatccttg gattattggc agcttatgct
     3481 ggtggcttcg ttgctacatt cttcttcggt attcctaaag accgtttaga aaaagaagaa
     3541 ttagcgactg aaacagccac agtaaatgaa gtgcctgaaa aagtagtacc tcaaacttca
     3601 gctgaaagtg tgactatcct ctcatcagtt gctgacggaa cagttgtttc tttagataaa
     3661 gcaagtgatc cagtttttgc acaaaagatg atgggtgaag gctactttgt agaaccagaa
     3721 aacggacata tctattctcc agttactggg gtagtcagct ctgtcttccc aacgaaacac
     3781 gctattggga tcacaacgcc aaatggttta gaaatcttgc ttcatatggg aatcaacaca
     3841 gttgacttag gcggtacgcc atttgatgtg aaagtaacag aagggcagca agtgacacct
     3901 gatacgcttg tagcagaagc tgacttagaa gcgatcaaag cagcaggcaa agaaacatcc
     3961 atgatcgtct tggtaaccaa tatggatcgt gtaaaaaact ttgtcttgga aaaaacaggt
     4021 aaagcaaaag caaaagcacc tgtgatggat gtcaaagctt aatatgatag aaacaataga
     4081 aacgaaagaa gaaactgaaa tctatttttc agcttcttct tttttattat ttattgtttt
     4141 ctgctaaaat ctgataaatt cgtgtcacat cagatggtgt tccccgtaat tcataatctg
     4201 ccaagaaagg aaagccaaat gtttgtgcat attgtttggc tgttagacaa tactgattat
     4261 tgaagttttt atttccgcta ccgactacac caagacaaag tttatgattg tcttcatgtt
     4321 ccagatattc acgcatcgtt tcggtcaaga tttctgtatc accgttatct aaaccatttc
     4381 cgccgtctaa ataagtagga acgaaagtaa aaaatggttc tgtttctttc gtaaaatcac
     4441 tattttcatg gatttctttt aaagtaactt caggattgac aggatcttct gcatgcattt
     4501 tttcagcata ttctgctaga tgtttggcaa aggcacgcgt atttcctgaa atcgatatat
     4561 ataaaatgtt catggatcat cctccaattc tttcctttta gtatagcatc ttttttaagt
     4621 tttttggtgg tgtaatttgg aaagggacta ggcgctttgc ttgtataatg agaaaaaagc
     4681 cggtagaatt atatttctat taaagttttt attaattaag taaaaataaa aaaggtttgt
     4741 tatacttttt gataaaagcg gttttatttt ggaggatgct tacatggata cagagcaaca
     4801 gaaaaaagga attggtttaa ttccacttgc tgccttagta attggttcag cgattggagg
     4861 tggcgtattt ggtattatga cggacatctc cggatcggct ggcggcccag ctattttcag
     4921 ttgggtactc gtaggaacag caatgttgat gctctccttg tcgatcaata atatcaataa
     4981 aaaacgtcca gatttaaaag gcgggatctt tagttacgca gaagaaggtt ttggccgttt
     5041 cgctggtttt atcagcggtt ggggttactg gctcacatgc tggttaggca acgtagcttt
     5101 tgcaacattg ttgatgagcg cattaggata tttcttccca gtatttgaag gtgggcaaaa
     5161 tctggcatcg atcgtgatga gtacagtctt tttatgggga tatgcatggc tagtgaatcg
     5221 gggagtcgaa aatgctagtt tcgtcaatgc tatcgtcaca ttctgtaaat tagtgccatt
     5281 atttttattt attgtagtag ctatcagcac gttttcgatc caacaattca ttgataactt
     5341 ttctagcgac attatattga atgcgaatgg acagccgatc ccgttttcca gtcaagtatt
     5401 gagttgcatc atggtgatgc tttgggtatt tgttggtatt gaaggagcct ctgtcgtagg
     5461 ttcacgagca aaaaaacaat cagatgttgg gaaagcaacg attctaggga tattcggctt
     5521 gattattatt tacgtcttgg tttccatgct tccatatggg acaatgacga tgaatcagct
     5581 gcaaacgatc aaggcgcagc ctgctatggg ctatgtgttt gaaatgatgg ttggtaaatg
     5641 gggagcagtc gtgatcaacg gcggtttgat catttcttta gttggtgttt ggctctcatg
     5701 gacgatctta ccgattgaaa caatgggaaa catggctgaa gacggacttt tgcctaaagc
     5761 atggggaaaa ctcaacaaaa atggggcacc aacttatgct atcgtattga cgacgttatg
     5821 tacgaatgtc tttttacttt cattattatt cactgacagt gcttataact ttgcttacac
     5881 acttggtaca gcagctattt tcttcacgtg gcttttctta ggattgtacc aaatgaaact
     5941 ttcttatcag cggaaagaat gggtccaatt tttagtaggg cttttagcaa gtgcctttca
     6001 agtatgggct atgctagtcg tagcctttaa tgaagtaatg cttgttcttg ttcttttctt
     6061 gccaggcatt tatttttacc tcaaagcacg taaggagcaa aacgagcctg tacaacatat
     6121 ccacttagat aagattttac ttataggtgt gacgatggtc ggagtgattg caatggtttt
     6181 atttgccact gggatgcttc acgtatagaa gtataaaaga agtataaaga gaggttgtga
     6241 gcctgtcgtt tattcaaaaa catactagga aaggagctgt gacacaaatg ttgtcacagc
     6301 tcctttttca gaataaacgg tgtttaagag acagccaatc ggcaataagg ctgaacgtct
     6361 ctttcacagc ctcttttttg atgagtcatc atacattttt tcgcttaaat acgagatatc
     6421 ctaatgctaa gaacaaaacg atgtaagcta aattaccgaa tagcatttga ttagtagaaa
     6481 gatgagtcaa ttgcttcatg atctcttcgt ttccaatttg gttttgcaga ttcaacatac
     6541 tgatcggatt ccatttgatc cactcccatt tttggatgag tgcaataagg ataccagata
     6601 tgattgacga agcaaaataa aagacgattc ctgctgagat ggatgcgccg gaactattga
     6661 taaagcaagc aatcatcaac actaaactta aaatcagcca taaaccgata taactaccca
     6721 aagtataagt gaacaagctt tggatcagtg tttgaccagt agaaaccttc tccgtgaagg
     6781 aaatcgaagg gaaaagaatc agtttcatca acacagtgac aataatagct aaaaggtata
     6841 aataaacaga ataaataact aatgtgatcc atttgcttac taatatttct cctcgagaat
     6901 actttcgata aaggagattt ttcaatgtac catattgtgc ttccatcgaa atgatcgtgc
     6961 ttgcagctgc aatcatgata aagacaatcc aagatgtggc actaaaaagc tgagcagtca
     7021 tttcaactgg atcaatgatc gtcgtgtatt ttttggctag aagtgctgtt cctatgagca
     7081 aaacaactaa tagaacagat aaaacagcag ttgacttttt cttgatcaat ttaaataatt
     7141 cttgttttac aagcaatgtc atttttcttc ttcccccttt actgaatcca gaatttccaa
     7201 tagagaagat tccaaatcat tcgtcagatg ctggacgtct gtcacatgga tattttgtgc
     7261 agacaatagc tggatcacgg ttcctaataa ttcttcgttt tcttttaaaa gcttgatttt
     7321 atcaggatct tccaaagtat atccagcttc tgtcaagatc gttcgagcag ctagatcatt
     7381 tgttgtagag ataacgatga aatcttgcgc tgtttggttc aattcagcca ttgtacattg
     7441 tttgatgatc tttccttgat tgatcaggat cagctcatcg accatttttt caagctcgct
     7501 gagtaagtga ctggagatca agaaagaggt gccctgagta gccaagtcgg taatgatttt
     7561 tcgcacatct cttgttgctt gtggatccaa accgttcatc ggctcatcta aaataacgat
     7621 agacggatgg ttcagtaagg caagagcaat tcccaatttt tgtttcattc ccaacgagta
     7681 ggatttcgct tttttgtgaa tgtacttttc catcttgagc tgattcacga tagtgtcgat
     7741 agcagataca tcgttggttt cagagaataa cttcagatga tcatagcctg ttaagaatgg
     7801 atagataccc gggtattcga tcaatgctcc tacttgttcc aaccctttat gactagaggg
     7861 agaaatctca ttttcaccaa tacagattgt tccatctgag taatggatca gtcctaaaat
     7921 agctttcatg atcgttgttt ttccagcgcc attaggacct actaatccaa cgattttgcc
     7981 aggggataag ctaaaactga catcgctgag ggcttgtttg tgaccaaagt tcttggataa
     8041 ttcttggacc gaaagacttt tcaaaaatat tcactccttt tctatagata gtacaagcat
     8101 acacctgatg agtggagaag tcgctaggtc attggactta tttcttattt tttcataaaa
     8161 aaattgaata ttaaataaaa aggcttattt tttctgatca gtacttattc caagtgtcta
     8221 gtggccgcta gtaatcttga tgccaatgat actgatgagt agcatcccca caaagaacca
     8281 agtggaaaga ttcagcttat catgaaacaa gaccacacca attatgaccg aaccaactgc
     8341 gccaatccct gtccagatag gataagagag actcatcggc aaacttttga ttgcctttga
     8401 caaaaagtaa aaactagcaa tcatgccaat cactgtgtaa aaagaataat tgattttaga
     8461 aaaaccatca ctccatttca tcatcgttga ccagaatact tccaaaattc ctgctatgat
     8521 taattccatc catgccatac ttacattcct ccttaactat aaaaaaatac acaaaaagag
     8581 gaaaatcatc ccttcaaaga cctaatggaa tgatcatcct ctttatccta cccggtggca
     8641 gattgtatat ctttttctgt agtatagcac acctatccag atatcggcaa tctcatactt
     8701 tttagtaaag tgtaccaagc actgacggat atatcgttag cggaaaagaa gatgaatgct
     8761 ttgcaatttc atagaaagaa gttgttattt attaatcatt taaaaaaaac agtaactaga
//
LOCUS       DADVXB010000119         8573 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.122, whole genome shotgun sequence.
ACCESSION   DADVXB010000119 DADVXB010000000
VERSION     DADVXB010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.122"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(263..940)
                     /gene="nth"
                     /locus_tag="KB902_002204"
     CDS             complement(263..940)
                     /gene="nth"
                     /locus_tag="KB902_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBB6808990.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(947..1645)
                     /locus_tag="KB902_002205"
     CDS             complement(947..1645)
                     /locus_tag="KB902_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6808991.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            1913..3097
                     /locus_tag="KB902_002206"
     CDS             1913..3097
                     /locus_tag="KB902_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBB6808992.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3103..3546)
                     /locus_tag="KB902_002207"
     CDS             complement(3103..3546)
                     /locus_tag="KB902_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6808993.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(3772..4059)
                     /locus_tag="KB902_002208"
     CDS             complement(3772..4059)
                     /locus_tag="KB902_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6808994.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4230..5582)
                     /locus_tag="KB902_002209"
     CDS             complement(4230..5582)
                     /locus_tag="KB902_002209"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBB6808995.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            complement(5855..6301)
                     /locus_tag="KB902_002210"
     CDS             complement(5855..6301)
                     /locus_tag="KB902_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6808996.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6537..7463)
                     /gene="cysK"
                     /locus_tag="KB902_002211"
     CDS             complement(6537..7463)
                     /gene="cysK"
                     /locus_tag="KB902_002211"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBB6808997.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(7602..8489)
                     /locus_tag="KB902_002212"
     CDS             complement(7602..8489)
                     /locus_tag="KB902_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6808998.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT         2334 a         1757 c         1423 g         3059 t
ORIGIN      
        1 atagatacgt cacttattta tataatcctt tggaatactg gacttatttt ataggtatat
       61 tggaaggcat tattttctac atcgggtatt ttcccaataa aaataacaac ttttattttt
      121 atcgcaataa attgtaataa gttaccatcc tagctactga gtatgtacat ttactttttc
      181 atgcaaaaaa gataaacgaa acagcttttc tccataataa caagataatt catacattta
      241 tttgcaatta aagaaaccac gtctacaggc gtggtttctt ttttagcgcc ttttctttta
      301 gacgcatccg atttttccca tcttgacata ttgatagcaa aggacatacc tcgcacttgg
      361 gatttcttgc cgtgcaatga tatctaccaa aaaaaatcag tgtatgatgt gtctttaccc
      421 ataattcttg tggtactttc cgcatcagtg tttcttctac ttccatgacc gtagcatcta
      481 gtttgcagat cctcaggcgt tttgagacac gttccacgtg ggtatctact gcgattgctg
      541 gtatcccgaa tgcatccccc aatacgacat ttgctgtctt tctgcctaca ccaggaagag
      601 acatcaattc ttctcttgac gttggcactt gcccatcgaa acgttcaatc agctgctgtg
      661 cacacgcttt gatgtttttt gctttatttc gatacaaacc aatcgttttt attttaagaa
      721 tgatttcatc gattgaagct tctgctaacg catcgggtgt cggaaaagag gcaaacaaat
      781 ctggcgttgc tttattcact gatacatctg tcgcctgggc acttaagatc actgcaatca
      841 ataactcaaa tggattattg tgcttgagtt ctccatgtgc ttcgggaaac attccataca
      901 tcgtttctag agcttccatt gttttttgtt tgcttaacat attccgctac tcctccaacc
      961 aatttttcag tgagactttc ggcaattctt cttgttgagc tgactgttct acttctcttt
     1021 gaagaagctg ctgttttctt cgtttttggt cttcttccac ttgttgtttt gtacgtagat
     1081 tttttctttc ccacgatagc aaaatgcggt caacgtaatt aaaactataa gcctgattta
     1141 atacggcttc ccgcagtgct agcttcaaaa tttccggctg ataatggtct tcttctagcc
     1201 attgtccgat ccgctggaac tcgatcgaag aaagcgggcg tccaaattct tgttcaaata
     1261 attgatacac tgactggatt tctttttctt gtgttttttc ttcgtatttt ttttcttgtg
     1321 tttttaaata ctcacctaat agatcataga tggggtaaag attatatcga tctgcttttt
     1381 taccgttgac aatcgtcgtt tctatcttga taaatccatt tgttacgaga cgatccagta
     1441 tttgaaaaat ctgatcttgt ttgattccca tatccatagc aatcatctgc aaatcaggga
     1501 aagtatctcc ttcaagctgt gccatatgca actgtagaac aaataaaaat tcttcagatt
     1561 gtagaccgat cctatgataa tttttaagta aaagattaga tatgactgtt tgtccagcgc
     1621 ttaagtaatt ttctaaattc aacatgattt ctcctccgct caatcacagt atacgtaaaa
     1681 aaaacatggg aagcaagaac aggtttcttt tctatttact tcactgatcg gtcagattta
     1741 caatgtcgtc tacttgattt ttgtttgttc atgtttttga tgcgtatctt cacttttcgg
     1801 aataaataaa ttaagtagat ttcgctgttc cttagaatgt tgacaaggaa acaaaattac
     1861 tatacactat ttttgtttcc aagttaacat tattgcataa aggagttttt acatgtacag
     1921 tttcacaaat aaacattcta aagtttttgg atacgtctct gtcttattca ctggattagg
     1981 atttactatc gtcagtcctg tacttccgtt tttaacgctg ccttattctc actccataca
     2041 tcagcaagct ttctatatca ctttgctcat gtctgtttat gctctagctg ccttcttatc
     2101 tgcccccatt ctcggtagct taagtgatca ttttgggcgt catccgatcc ttattatcag
     2161 tttattagga tcaagtatcg gatatttgct ttttggttta ggaaattcga tatggatgtt
     2221 gttccttggt cgtatcattg aaggattgac ggcaggagaa atctccacct tatatgctta
     2281 ctttgccgac atcacggaac ctaatgaaag aaccaaagtt tttggatgga tgggtgcttt
     2341 agtcggtata ggaacaacgc tgggtcctat tatagggggt ctattagctg agttggggaa
     2401 ttctgttcct atatttattg gagcactctt tactttctta aatgccgttt atggctacac
     2461 atttatgcta gaaagccttc caataaaaaa acgttcagta gatttaagtt tctcccatgt
     2521 aagacctttt caccaattac aacaattatt caagatttca tccgttattc ctttattgac
     2581 agcaggtttt gctgtttggt tggcagctgg ctctcttcaa tctatctttt ctcaattttc
     2641 gattgacgcc tttcagtgga aggctgggtt ggttggttta agcttctctt tgattggaat
     2701 cttggatact gtctcgcaat tgttcattat gcctcgattg ctcaaaaaat tttcagaaca
     2761 gcagatcaca agaataggga tgttcagtga aatcctcgcc tatctattca tcacattatc
     2821 tggaattctt ctactgccga ttttgttttt atttgggatt atctgttatg gtttcggtga
     2881 ttctattttt actcctgtat tcaatggcca actatccaat tctgtctcag ataaccagca
     2941 aggtcttgta atgggcggta cccaaagtat acaatctcta tcgcgcgtca tcggcccgct
     3001 aatcgcagga cagctttatg ctgcagcacc atttcttccg acggtattcg gatttttgct
     3061 tatgattttt gcctattatc actacaataa aaaatagtag cttcatttgc tacttcgtat
     3121 aaattctctg tatcgaccga taaaacgaaa tactgtgtca aattcttctt ttgacatatt
     3181 ttcaaataca gtagcatctc gctgtaccca tttttgatgg agttgctcgt gtctattcct
     3241 tattttttgt ccgattggcg tcaattgaaa atagatttct tttttattct cttcgctttg
     3301 ataagtgttt atgatccctc tagctatcag tttttttgtt agcttactga tggctcctct
     3361 agtcatgtaa ctagcattcg ctaattttgt cacgttagga tcagggattt tcccgatatg
     3421 ttcaatcact tctagttcat ttagagtaaa tcctgcaaat tctttttcca tttctggttt
     3481 attacgatga ataatctcat tagctaaatc cagatattct tctattagca gttgtctttt
     3541 atccatttct acaccttctt tttctttcat tatattgttt ttttgtttcc tattcaacaa
     3601 agataaaaat attttgtagg aaaacccaat ctgaaaccaa gaaaaaaagg ggttgacaaa
     3661 gcttgtcata accccttttt ctgattaaaa gatagtaaag agacagtcat cggtaattgt
     3721 gatgattttt tgtcatcact taaggatgag cggccttttc aaaaactgtc tttaaagatc
     3781 atcatcagtt tctagcacat atggctgacc ttcatatgtg tactctgtat tcaatgtgcc
     3841 gtcattttca tctgagtaga tgcgtctact gaaaggaaaa cgatgagaaa cattatcttt
     3901 ggcgtcattt gctggcatcg tgtaatattc ctcttgcgtt tcattcaact gagagagtac
     3961 ttgatctgcc aactcatcaa tattgatcgt taatttcttc gaagcacttt tataatcttc
     4021 taaaaatgca tcttgttgga caaaatattc tttattcatc ttctttctca cctttctttt
     4081 caaaatcaaa taaagctgct tgttctttta tgtaacagct ttatctttgc tgcttattgt
     4141 gacaaaaaat tcgaagaaag acaactaatt gtacttttca caaaaaaaga cagagggtcg
     4201 tgacaaaatt gtgtcacaac cctttttctt tattgtgcag tttcgatttc gcctagcgct
     4261 gcttgtgcaa gtaggttcaa gtaattccat gggcggtcaa aatgtggttg gaagaagaaa
     4321 tctgaaagtg cgagatcttc tacagtcatt ttattttgaa cagctaaaga catggtattt
     4381 gctgattgtg taatgtcgta tttggacatg aactgagcac ctacgatacg attcgttcct
     4441 ttttcataga ctagctccat cattactttt tcagtagttg gcatgaactc tggacgataa
     4501 ttatcttcaa atacagtcgc ttggacttct agatcgttca aagttgcgct ttctttggtc
     4561 acacctgtcg aaccgatcgt ccagccaaat aggtaaagtc ctgaagttcc ttgagtacca
     4621 cgatacgcca ttttatgatc tgtcaagtta tttcccacaa gcaaaccttg acgaacggca
     4681 tttgttgcca aaggaatata gttttgcgtg ccacttggat tgtagttgac tactgcagag
     4741 tctccagctg caaaaatgtc tggattactt gtctgcatgt attcattcac tttgattgcc
     4801 ccgtttggca gtgtatctac ttttccttcg atcagttttg tatttggacg gaagcccaca
     4861 cataaaatga ccatatctgt atcaaatgta tctgttggtg tagctacttg tttcactttt
     4921 ccttcttcat ctgtgataaa ttcagtaaca ttttcgccta gcgcaagagt aacaccgcgg
     4981 tctgtcaatt ctttttctaa gatatctgtg aatggtttat ctagatattt attcaagatg
     5041 cgatctaatc catcaatcaa tgtcacttgt tttccagatt cgacaaaagc ttctactaat
     5101 tcaataccga tatatccacc accaacaatt actacacgtt ttgcttcttt cgcttgtgca
     5161 ataatttcat ttgcttgatt gtagtttttg cataggagta catttttcgc atcgattcca
     5221 ctaatcggtg ggataatagg ccatgaacca gttgtcatca ctaatttatc ataagaaacc
     5281 gtttctgttt ctcctgtttt cagatctttt gccgttactg ttttattttc tgtatcgacg
     5341 tctgttacat cgtgttccat tttaactgtt gctcctaatg aagataattc ttcaggattt
     5401 gagtagaaca agcctgctgg gtcctttact actccgccga cataaagtgc gataccgcaa
     5461 gataagaaag aaatattgtc atttctttca tatactgtca cttctgcttc tggatgattt
     5521 tttaaaatac tttttacagc tgcagtacct gcatgagtac agccaattac tactactttc
     5581 atttatggtc cctccgatta acattttgtc cttcgacaaa actactataa cagaaataaa
     5641 acggatacaa cagtttaatg cttgtgaatt cacaaaggtt tgtttgtagt ttcattcctt
     5701 ttcaagcata agaacccaat atctacaaga ttcttatttt aataatattc acttttatat
     5761 ctaagattgt gaataaaaga caaaaaaata aaaaagctag cgtttttttt acacagctag
     5821 ctttttttag gtataacact tgtagaaact gtttttacat ttgcgccttt tttgctgact
     5881 ctttacaatc cggacagagt ccatacaatt ccaaccgatg ttcattaatc tcaaaatcag
     5941 tcagtctgct tgcagccatt tctatatctt caagccctgg gtaatgaaaa tcaacaatct
     6001 taccgcagtt ttcacaaatt acatgataat gacgctttga actgaaatca aatcggctag
     6061 aagcatcgcc gtacttcatt tcttgaacaa atccaatcga agtaaataag cgaaggttat
     6121 tgtaaacagt cgcaacactc atatttggaa accgatgttc aagtgcttta taaatctcat
     6181 cagccgttgg atgggaatga tgttcaatca aatattctaa aaccgcgtac cgttgaggtg
     6241 tgattcgaat gttctctttt tttaactttt cgataacctc ttcgactaac ttattttcca
     6301 tgtaaacacc ccacgttgtt attctcgtct tatcatacta tttttacatt ttaaaatcca
     6361 cttaacatga aaagaaaatt caattttatt gtattttaat gaaaaaagac gtaaaacagt
     6421 cgcgttcact attctacgtc tctattcaaa taatttttct catcataaat ttttgtgtgt
     6481 tcttttcatc tttaaaagtt ttttacataa acctatctgg agaaaaacca agtgccttat
     6541 atctcttggt aaagggctgt agataaataa cgttcaccat tgtcgggaac cacagctaat
     6601 accttcttgc cttttcctaa ttcttttgcg acttttagcg cggcagcaat tgcagcgcca
     6661 gatgagatgc ctactaaaat cccttctttt cgcccaactt ctctagctgt ttccatcgct
     6721 tcgtctccac taatagaaag gactttatca tacacagaag tatccagtgt tttaggaaca
     6781 aaacctgtac cgattccttg gattttgtga ggtcccgctt ctttcccttc taaaatagca
     6841 gattctgctg gttctacccc gattaattcg attttcggat acacacgttt taattctcgg
     6901 ccagcgccag tgatcgttcc tcctgtaccg atacctgcaa caaacgcgtc caagccattt
     6961 actccaaatg cttgatgtat ctcaggacca gtcgtcttct catgcacaag aggatttgct
     7021 tcattttcaa attgtaatgg taaaaagtag ccgttttctt ttgccaaacg ttctgcttct
     7081 ctgattgatc cagaaatacc atccgcacca ggagtcaaaa tcaactctgc gccgtaccct
     7141 ttcatcaata aacgtctttc gatactcatc gtctcaggca tcacgatgat tactttatat
     7201 ccttttgcaa ctcctaccat cgacaatccg attcctgtat ttccagaagt aggttcaatg
     7261 atagtatcac ctggtttcag tagaccatcg tgttctgctt tttctatcat acttaaagca
     7321 atacgatctt ttacacttcc tcctggatta aaaaactcaa gctttacaaa aacatctgct
     7381 gaatcttctg gtacgatttt atttaatttg acgattggcg ttttgccaat caattcggtg
     7441 actgagttat agatagctgt catcttcaat tcctccttgt ctttgctctt cttacttatc
     7501 ataatacaat ctgttcattt atggcgagtg attcgtcttt gactagcaaa aaaaagcaaa
     7561 gatataccat atatggtaat ttctttgcct ttttatctaa atcaaacgtt tagttcttga
     7621 ccaactaata aagaataact ggacatagac atgccatttt tcgccattag atcatcaaca
     7681 gacatgccaa atttttgtgc aatatcccat agcgtatcac ctgacacgac tgtatatgtc
     7741 tgaccattat ttgtatttac atctgttgtt gaagatgatg acgttgaagt cgtcgtagta
     7801 gtcgttgttg ttgtacttgt ggttgttgta gccgaacctg ttgatggcgt atcaaaacgg
     7861 gttaaattat aagtattaat caatgagttc aatttggccc cataatttgg atcggtagca
     7921 taacgacctg tcaagtacgc tgttgcatca taaaaacttg ttgtattgct tttccacacg
     7981 ccagcataat gataatcgcc cgtggaaaaa ctggttgaac gaagaacatt cgcatggtct
     8041 tggaaggatt cccaataaga agaatatttt cggaatggct cattcatcgt tacccattgt
     8101 ccgtttacat attctttggt tgccatataa acgacctgtc cgttatagct tcctttcaca
     8161 ccgaatagat tataatttgg cgcactagct aatccggaag tgccatatgc actttccaac
     8221 aacgcttgag cgatcatgac tgaagcatac aagtcattac ttgcagcaac ttctgacgca
     8281 gaccagccga tttgatcgat aaacgcttga ggatcagcga ctgtttgaga tccttgttca
     8341 tctgcatgaa catgttgcgg taccgctgta accatcatcg gcccaactaa aagactcgtt
     8401 ccaattaaag gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgc
     8461 cgggcactgc gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa
     8521 taaaaagttc tcttcttaaa acaaacttaa ttaattaaat tatactttta att
//
LOCUS       DADVXB010000120         8481 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.123, whole genome shotgun sequence.
ACCESSION   DADVXB010000120 DADVXB010000000
VERSION     DADVXB010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.123"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..516)
                     /locus_tag="KB902_002213"
     CDS             complement(<1..516)
                     /locus_tag="KB902_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6808999.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRK"
     gene            complement(615..965)
                     /locus_tag="KB902_002214"
     CDS             complement(615..965)
                     /locus_tag="KB902_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBB6809000.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(1122..2651)
                     /gene="ahpF"
                     /locus_tag="KB902_002215"
     CDS             complement(1122..2651)
                     /gene="ahpF"
                     /locus_tag="KB902_002215"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBB6809001.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(2661..3224)
                     /gene="ahpC"
                     /locus_tag="KB902_002216"
     CDS             complement(2661..3224)
                     /gene="ahpC"
                     /locus_tag="KB902_002216"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBB6809002.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(3368..4030)
                     /locus_tag="KB902_002217"
     CDS             complement(3368..4030)
                     /locus_tag="KB902_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6809003.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            4214..5860
                     /locus_tag="KB902_002218"
     CDS             4214..5860
                     /locus_tag="KB902_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6809004.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            5851..6933
                     /gene="uxuA"
                     /locus_tag="KB902_002219"
     CDS             5851..6933
                     /gene="uxuA"
                     /locus_tag="KB902_002219"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6809005.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(7041..>8481)
                     /locus_tag="KB902_002220"
     CDS             complement(7041..>8481)
                     /locus_tag="KB902_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809006.1"
                     /translation="ADHFHMSESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFE
                     GIDPAYCYYRLFGRYCNESVSYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKIN
                     AFLALYGLSISFSNNGRKSFSGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMM
                     NTFFKKEVLDRLNSGMIDKLYFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVD
                     ILRPNLPICREQRILVNILARLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESF
                     CTVFDLFIPEKEKILYSLAFARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAI
                     EQFYMDFREQNQHLLPVILEKENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISK
                     DLIVKIEQIFSNESIKIQNDFMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKK
                     VIMRISEYIFELKEEALMDQSKKENQVTS"
BASE COUNT         2710 a         1563 c         1541 g         2667 t
ORIGIN      
        1 ttttcttatt ctgatgaaat tgataatctc ctggatgccc atgaaaatca aaataaagcc
       61 gaatatttgg aatagaagca tcaaactttt gaatggattg aacaataaga cgaatccgcc
      121 aatcaacaac agaatactac tataaacact ccaactttta gcttttgtat tcatgctgaa
      181 gaacaactgg aacaagctgt tgatgataac agctaatcca agaagaatcg gcaggataga
      241 aacgattgca ggtgcaaaag catagacgat cagagctaag atcaggaaaa aaagaccact
      301 gaacagaccg atactccaag aacctgtttt ccttttaaaa cggtaagcct caaaaagatt
      361 caacaaccca agcaaaacaa gataggcggt gatcagataa ccgataaaat gaaaaacagc
      421 agaagggttt agcacaatcg caatcccaga aataatataa acagcagctc ttaataaggc
      481 gtatttttga atattttgtt taatcgtctc aaacatataa gaaaacctcc tttgacttat
      541 tttaacgtga actagtcatt ttaccaaatt aaatgttaca aaatgagcga aggagaagaa
      601 tatctctgga aaaatcaact tctgaggatc ttttccattt ttttgccttt tgctagctca
      661 tcgatcattt tatctaaata acgaatttct ttcatcaagt tatcctcgat gtcttctact
      721 cgtacaccac aaacaacacc tgtaatcaag gaacgtgaag gattggggac aggggcttcc
      781 gcaaaaaatt gttcgaaagt cacttgtttt tgtagttgat attctagttc tgtttgggaa
      841 taacccgtca gccaacaaat gatttcatct acttcctctt ttatacgatc ttttctctcc
      901 gcttttgcta catacatagg ataaacgctt gcaaaacttg tcgtaaaaat acgattttgc
      961 gccataatca gtcacctttc tttttttcaa attatttact acttatagta tataagaaaa
     1021 agagaagaaa aagcgattat tcaaaaaaac aaaaaggatt gtgacaaaat tcttgtcacc
     1081 atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg catcagataa
     1141 tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat ttgtttgtat
     1201 ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc gccatttttc
     1261 tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca atccgtatta
     1321 gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat ctccatcgta
     1381 cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc tttcgtcgct
     1441 gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa gatttgatct
     1501 gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc agccaaatcg
     1561 attgctgctt caacaccaga attaccacca ccgataacag caatctcttt tcctttaaat
     1621 aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc tttttcgcct
     1681 ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt tgctttaagt
     1741 gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa ggaaacggcc
     1801 tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac ttgctgcatc
     1861 aattttggac cttctgtgta agaggtacca atcatatttt caatccctag tgtttcaacg
     1921 acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg tgctgcatag
     1981 atagctgcac tactagctgc tggtccaccg ccaattacta atacatcata aggttctttt
     2041 tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg ttcgatcgtc
     2101 atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc catgattttt
     2161 ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt aatatttgga
     2221 tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg acaagtcaag
     2281 ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag actcaaagat
     2341 tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa agaggaaaat
     2401 tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac tggattgata
     2461 gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg agacatttct
     2521 gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc caaactaaca
     2581 gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg tttagtttct
     2641 ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg tttcaatgtt
     2701 tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg tacatattga
     2761 gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc tgcattgatt
     2821 tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg agctaatcct
     2881 tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc accgatcatc
     2941 acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg agtaaagtgg
     3001 gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact gtattgttct
     3061 tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata gaagcaaaga
     3121 atactccagt tccccataag atctttttca ctgacttcta aaaattctcc ttgatgataa
     3181 gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa acctccaata
     3241 ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa tggatatttt
     3301 gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa gaggtcgcaa
     3361 gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc tgttctttca
     3421 gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt ttatcaacta
     3481 aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc ccctgaatgg
     3541 tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac cagttccaaa
     3601 cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct gcacggaaaa
     3661 aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc gtttctagca
     3721 ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc tcttccaact
     3781 gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa acatacgtac
     3841 cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat gcttcgcgaa
     3901 tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt ttccttccag
     3961 gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt gattgcaagc
     4021 tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac agaagaggtc
     4081 tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt aaaattttgg
     4141 ttgacatagc gatttttatt gtataaaatt cacttgaata caaaaactaa tatgttagtt
     4201 taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg aattatctca
     4261 aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg gacaaaaaaa
     4321 tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg cagaaatcgc
     4381 tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg aaacattcga
     4441 tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg aagtggtcat
     4501 gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca gtctgtattg
     4561 tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa atcctagttt
     4621 acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata caaataataa
     4681 atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat cacatacaat
     4741 gagtattctt gctgcgctac tttataaacg ttttttatct ggagcttggc cgattgcact
     4801 tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt tgctaacgat
     4861 cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat acttatcgaa
     4921 tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga atccttcctt
     4981 gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt tccaaaccgc
     5041 aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt taatcatgga
     5101 agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct tgactgatcg
     5161 tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc ctttgcatac
     5221 gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg agatgaaaga
     5281 tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc cagttgtgga
     5341 gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg tgcgcttttc
     5401 taatccaaat attcctgata tgcctcagcg aatcgccacg gatacctctc aaaaggtggc
     5461 gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag acccgcagac
     5521 acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg gcattgatga
     5581 tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagactttc agcataagct
     5641 ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa tggctcctat
     5701 tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg gcagaaaaat
     5761 agaagaaatg ttcatcaaga tggtagcagg accgaatgcc gtacgaaaaa cattacagga
     5821 ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg gtacggatca
     5881 caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa agggattgta
     5941 ggcacattga tggatatacc agtaggagag gtatggccca gggagaggat caaagaacta
     6001 aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt caatgtgcat
     6061 gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta taagcagaca
     6121 atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat gcctgtattt
     6181 gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac gttagctttt
     6241 atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga acattccagc
     6301 aatgaatttg aattgccggg atgggaacct gagcgcttag ctcatatcaa atccttgctt
     6361 gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta ttttctccaa
     6421 tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc agatgatccg
     6481 ccatactcga tttttggatt acctcgaatc gtaaagaatc gagaagattt agattggttg
     6541 tgccgcatag tagacagccc ttataacgga atcactcttt gtacagggag tattgcagaa
     6601 gatccagaaa atgatgtata tgggatttta gcagaatttt gtcaaagaga tcgaatccca
     6661 tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga ggcaccgcat
     6721 aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta tgacaacgga
     6781 tttaacgaat acatccgtcc tgatcatgga agaatgatct ggaatgagac aggaagacca
     6841 ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt atgggaagca
     6901 atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt ttattatgta
     6961 aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat aagcattcgg
     7021 atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga ttgatccatg
     7081 agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac ttttttccag
     7141 tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga aggcaattgt
     7201 ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt ttgtattttg
     7261 atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact gatataaaaa
     7321 tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg atcatacaaa
     7381 tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac tggtaacaag
     7441 tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg gacttctttc
     7501 aacacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg ttgattgaag
     7561 ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag aatcttttct
     7621 ttttcaggta taaacaaatc aaatacagta caaaaggact ccaccatttc tcttgaataa
     7681 agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct tgtttcttcc
     7741 gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg ttgttcgcga
     7801 caaattggca gattaggtcg caaaatatct acagagggat caataaaaaa gtcaatatat
     7861 tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa attctcttta
     7921 catattttta atagaaaata taatttatct atcataccgc tatttagtcg gtcaagtact
     7981 tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc atcataaaat
     8041 tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata ttgaatttgt
     8101 acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga caaaccgtac
     8161 aatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc actatagttt
     8221 gtttgctgac ttaaactgat aatcgaattt gtctgacagc tgaacaaaga agtcaagatc
     8281 tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca gtaagccgga
     8341 tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg cagttctgtt
     8401 agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa atttgattca
     8461 gacatatgga aatgatctgc t
//
LOCUS       DADVXB010000121         8477 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.124, whole genome shotgun sequence.
ACCESSION   DADVXB010000121 DADVXB010000000
VERSION     DADVXB010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.124"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(48..185)
                     /locus_tag="KB902_002221"
     CDS             complement(48..185)
                     /locus_tag="KB902_002221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809007.1"
                     /translation="MDQKRIRVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(280..858)
                     /locus_tag="KB902_002222"
     CDS             complement(280..858)
                     /locus_tag="KB902_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6809008.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            1027..1224
                     /locus_tag="KB902_002223"
     CDS             1027..1224
                     /locus_tag="KB902_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809009.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            complement(1326..2144)
                     /locus_tag="KB902_002224"
     CDS             complement(1326..2144)
                     /locus_tag="KB902_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBB6809010.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            2309..4039
                     /gene="spxB"
                     /locus_tag="KB902_002225"
     CDS             2309..4039
                     /gene="spxB"
                     /locus_tag="KB902_002225"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBB6809011.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPIVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            complement(4469..4990)
                     /locus_tag="KB902_002226"
     CDS             complement(4469..4990)
                     /locus_tag="KB902_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6809012.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTVIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            5239..6861
                     /locus_tag="KB902_002227"
     CDS             5239..6861
                     /locus_tag="KB902_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6809013.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVMKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSHSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            complement(6990..7853)
                     /locus_tag="KB902_002228"
     CDS             complement(6990..7853)
                     /locus_tag="KB902_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6809014.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLEGNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
BASE COUNT         2725 a         1670 c         1559 g         2523 t
ORIGIN      
        1 aacatgcttt tcttaaatag atagaacatc atattacata aagatgttta tttttttatt
       61 gctgtgaata atgtcaaaaa tcctacgaca ccaactactg tccaagtcaa atgaccttga
      121 tccaaataaa taagcatcgt gacaaaacta gtaatcagtc ctacacgaat tcttttttga
      181 tccatctgca tccctctttg aatactagta tcactcggat atttgatcgt ttatttattt
      241 tttctatatt tttctcttaa attttaaacg cggatcattt taccgatatt gtgattcgat
      301 ggtacgactt gggatgatcc aagcagctag aatcacgatg tttgcgatca gcacggctac
      361 gggcgctact aaatacccta agacaattcc taacacattc aagccaatcg ataaatacga
      421 tttcttgtaa ttattcaaca tcgccttcaa tgctttctcg tggcctttat ttgctttgac
      481 aagttctttt gccaagatat aatacgcaat attagcggtc aaggtaacaa aaccataagt
      541 catttctgga gccaggctat tgatgtactc actgatccat gaagttgcaa acggaaaaag
      601 cgaaagcgca aaaacaaaga aactgttcgc ccataagacc cgtccattta tcttatgtac
      661 aacttgaaat aaatgatgat gattgttcca ataaatcgct aaaatgataa aactgacaat
      721 atagataaaa aatcggtaac ctaatgcagc gagcgcctcc cacgtatctc cgttaggttc
      781 atgaagttct aaaactaaaa tagtcatgat aatcgcgatt acagcatctg taaatgcttc
      841 aagacgattt ttaggcatga tattctcctc cttttccgct ctattttaga tgataaacca
      901 gagaaaaagc aattgtttga tcatttaagt agatgaagta aaaatcagtc ttcagttgga
      961 ggtgttttta aacaatccct gttatacttt ttctatagta aagaatgaac aagaggaggg
     1021 ttttgtatgc gtcaaaaaaa tatgttctta aatatcttca tggttctttt agtgctaatt
     1081 gcagctagct tcgtcatcag tctttttgtc agtgtcctaa gcgggctttt atggtttgcg
     1141 gtcaaagttc taatcccaat cgcacttatc atctggcttg ttcgctggat caaaggaaat
     1201 acacatagaa aaaactatta ttaatgtatg ataccattca cttcattatg atataactta
     1261 ctaaaaaaat agggtcgcga tataagttcg cggccctatt tgatatatca tatatatttt
     1321 tttatttatc ctaatgccac atccaaaatc atcataatga taaatccact catgacgcca
     1381 aaaactgcaa aatgacgttt gctggacaat gtctgctgtg cttcggggat caattcttcc
     1441 accacgacat aaatcattgc tcctgcggca aaagcaagtg cataaggaag cagcagctcc
     1501 actttcgtta ctagtagcgc tccaatcact ccagcaattg gttcaacgat tccagaagct
     1561 tgtccgtaaa caaaggcctt tttacgactc agaccttctt gtcgcaacgg gattgataca
     1621 gctgctcctt ctgggaagtt ttggatacca atacctagcg ccaccgaaac agcggctaat
     1681 atagcggctg tcggattatc cgcagttgct gctgcaccga atgctacccc cacggctaaa
     1741 ccttcaggaa tgttatgcaa tgtaatagaa aaaacaagca agatcgtccg ttttaaatgg
     1801 gtaggcaatc cttctgcttc atgttgtggt ccaaaatgca tatggggcag tgttttatct
     1861 gccatatata aaaacacacc gcctaaacca aacccaatac ttacaactag ccaagcaata
     1921 tctccatttt cttctgcttt tgtaatagcc ggatctaaca aagaccaaaa acttgcagca
     1981 atcatgacac cagaagcaaa tcctaacatc aagtttagca cttctttttt gatttcttta
     2041 aagaaaaaaa ccaacccggc accaagagct gtcataaaat aagtaaaagc tgtcccagca
     2101 agtgcttgct gccaaggttc aagtctcaat agccattcaa ccatgccatt cccctctctt
     2161 gaatctatct atgtactact ctagcatatt cccaaaaaca tgactacatt tttgtgaaaa
     2221 gacgaattag ttgggatttt cgataaaaag ttctatactc tagatacaaa aaatttatgt
     2281 atcatcattg ctaaaggagt gaaacaccat gtcaaaaatc aatgcaggaa tcgcaatggt
     2341 aaaagttctt gaaagctggg gtatcgacca tatttatggc attcccggag gatctttcaa
     2401 ttcaattatg gatgcgctat atcaagaaaa aaccgaaatc aactacattc aagttcgtca
     2461 tgaagaagtc ggcgcactcg cagccgctgc agatgcaaaa ttaacgggga aagtcggcgc
     2521 tgtcttcggc tctgcaggac ctggtgcgac acatttgatc aatggtttgt atgatgcaca
     2581 gatggaccat gtgcctctag tagcgttctt aggacaagtt gcttctacat ccatgaacta
     2641 taactctttc caggaactaa atgaaaatcc tattttcgca gatgtcagcg tatacaatcg
     2701 tacagtcatg acaccacaaa gtcttccgca tgtagtagat gaagccatta aagccgccta
     2761 tgagcataaa ggcgtggcta tcgtgactat ccctgttgat cttggttttg aagaaattga
     2821 cgaacaacct ttctccaccg ctcacactca caaaacaagt gtgatattac cagaagaaaa
     2881 agatttgcta gctgctttgc cttatcttga aaaagcaaaa aaaccagttc tttatgttgg
     2941 tcaaggaacg cgaaacggat ttccgcaaat caaagaattc tcagaacatt tttcagttcc
     3001 tattgtcgct tccgttctag caaaaggaat tattcctgat gattatgaaa actttcttgg
     3061 ttttgctgga cgtgtcgcta ctaaacccgg aaatgaagca ttggcagaag ccgatctgat
     3121 cttatttgtc ggtagcgact tcccatttgg acgtgcattt tttaatccaa ctgctgaatt
     3181 tatccaaatc gatatcgatg cgtcaaaatt tggacgacgc catgaaacat ctttgtcgat
     3241 cctcggtgat gcaaacacag ctttgcaaag acttgtcgag ttaggggatg ctcgccctgc
     3301 tgatagctgg tacctagcaa atcaagaaaa taaagaaaaa tgggtaaatt ggttgaaatc
     3361 ttttgaagat cgagaggaag aaccgattcg tccagaggct gtctataaag aaatcaatcg
     3421 tattgctgaa gacgatgcga ttttcgtcac agatgtcggt aacacgacta tccattctat
     3481 tcgtttattg aatatgaacg gtaaacaaaa acatacgaca tctggatggt tcgcaactat
     3541 gggtaatggt gtgccaggag gaattgccgc acaactaagc tacccagaaa aacaagtatt
     3601 taccttaagt ggtgatggcg gatttgctat ggtcatgcaa gatatcatta cacaagtcaa
     3661 atatcagctt ccaattatta atgttgtctt ttcgaatgat tcttttggtt tcatcgaagc
     3721 agaacaagaa gatacggaac aaaagaaatt tggtgtattt ttagaagatg cagatttcgg
     3781 taaagttgga gaagcgctcg gggcaaatag ctttacagtc acagaatact cgcaacttcg
     3841 atttgccttt gatgcagctg caaaatcaga tcgtcctgta gtaatcgatg tgaagatcaa
     3901 taacaagcgc ccattgccag tagaagatct gcatttagat ccaagaaaat attctgaaga
     3961 agaaatccaa gcattcaaag aaaaatatga agtccatgat ttgccagtat tgaatgaatt
     4021 atatgaaaag aggttgtgac aactgcgcta tgcttcgagt aataagaacg atggacagaa
     4081 aatagttcct catattttct aggacggcga tcttattacc gagaagcagc aggtggagca
     4141 ccgtttatca gaggttgtga aaaagctggt ctgcatcaag taataagaac agccaaacaa
     4201 aaatagctcc tcctattttt cgtttggttg ggcttattac cgcagatgca agcttttaaa
     4261 caccgtgtat caagaggttg tgacaactgc gctatacttc gagtattaag atacaatttg
     4321 tgtatatagc ttctcacatt tttgcataaa tttgtctcga cacctaaaaa tcacctcgtg
     4381 catatttgtc catgataaaa aagccagctt ccaattacaa cagtaaaact gtaatcggaa
     4441 gccggctttt ttatttgttt gattttgctt atctaaatgc atagacgata tgtgtgatac
     4501 caaataacat aaaatagaat ccaactaaaa agcttaatgt caacgcagaa gaaattggat
     4561 taaacaataa gaaaatacct aataaaattc ctaagatatt gacgatgacc gtaaaccaat
     4621 aatatccttc gcttactcct cttgccaaat cagcagtaaa taacgctaaa acggaatcag
     4681 caataaacca tactgcaaaa acaaaaggta atgctgcgac tcctgcacca atattgaata
     4741 agaaaaagac gccaactaga atatcgatga tcccgattat taagggcatc tttcctttat
     4801 atcctgttag ctcttttaat ctgttccgta caaacagttc aaatatccct ttaataaagg
     4861 caaaaatcgc aaagactact acaattgcaa ctaaatttcc gacagggtct tgaaatgata
     4921 acaatgagac aagtacaaat aaaattccca aaatcaatga gccccagtcg atggttcttt
     4981 tttcatccat tttcaatcct tctttcattt cttttacagt tttatagtac tccctcttat
     5041 aaataacgtc aaaaattatg ctgttgcaaa ctaataaatc ctatagtagc tattttcgct
     5101 cctcttttat ttttattttt ttcattctgt ttcacgtgaa acacaaagaa tgttcgattg
     5161 ccttgaatct tttacctttc ccctatataa ttctataaga cttgtcaaaa ctaataatga
     5221 taaaagtgag gaaaaaaatt gattactgta aatgatgtga gtttgcactt ttcagaccgc
     5281 aaactatttg atgatgtgaa tattaaattt acccccggaa actgctatgg cttgattggt
     5341 gcaaatggtg caggtaaatc aacgttcctt aaagtgttat caggggatct gcagccttcc
     5401 acaggttccg ttactatggg accagatgaa cggatggccg tattgaaaca gaaccattac
     5461 gactatgaag actatactgt acttgaaaca gtcatcatgg gacacaagcg tctgtatgaa
     5521 gtgatgaaag aaaaagatgc gatttacatg aaagaggatt tcactgacga agatggtatt
     5581 cgagcagctg aattagaagg agaatttgct gagcttaatg gatgggaagc tgaaccagaa
     5641 gcagctgttt tactgcaagg tctgaacatc cctgaagaat tgcaccatca gcaaatgagt
     5701 gaattaactg gtggacaaaa ggtaaaagtg ttattagcac aaacactatt tggtaaacct
     5761 gatgttcttt tgctagacga accaacaaac ggtctggata tccaatcgat caattggctg
     5821 gaagaatttt tgatcaattt tgaaaatact gtgatcgttg tatcccatga ccgtcacttt
     5881 ttgaacaaag tatgtacaca tatggcggat ctagattttg gtaaaatcaa actttatgta
     5941 ggaaattatg atttttggtt ggaatctagt caactagcgg ctaaacttca agcaaacgca
     6001 aatgcaaaaa aagaagaaca aatcaaagaa ctccaagaat ttattgcccg ctttagtgcg
     6061 aatgcatcaa aatcaaaaca agcaacttca cgtaaaaaaa tgcttgaaaa aattacttta
     6121 gacgatatcc aaccttcttc tagacgttat ccattcgttg gattcaaacc tgaacgtgag
     6181 attggaaacg acttattgca ggtagaaaat gtaagtgtaa cgattgatgg aaagaaaatt
     6241 ttagatgata tatcttttaa tttgagcaaa gaagacaagg tcgctttcgt cgcagaaaat
     6301 gatataacaa caacaacgct attcaaagtt atcatgggtg aaattacgcc agatactgga
     6361 acagtacgtt ggggtgtgac aacaagtcat tcttatttac caaaggatac aacgaaagaa
     6421 ttcgatactg atctaacgat tttagactgg ttgcgtcaat atgcaagtaa agaagaagat
     6481 gataacacct tcttaagaag cttcttagga agaatgttgt tttctggtga agaagtattg
     6541 aaaccagtga atgttttatc tggtggagag aaagtccgtt gcatgctttc aaaaatgatg
     6601 ctttcgaaag ctaacgtact tgtattagat gatccaacga accatttaga cttagaatca
     6661 atcacagcat tgaatgacgg cttgatggca tttactggct caatcttatt tgcgtcacat
     6721 gaccatcaat ttatccaaac attggcaaac cgcatcattg ccgtttcgga taaaggtgtg
     6781 atcgatcgag ctgatacgac atatgatgaa tttttggaaa atgcagatat tcaaaaacaa
     6841 ttgaacgagt tatgggcata atggcctatt tagcttaaaa aataaaaaaa cagcgacctc
     6901 taagagatag gatgctcatc tatcttttaa gagtcgctgt ttttgttaca atcaatttct
     6961 gggctttttt acagaatgag ttactgtttt tatcgactga tccccattga aaaaatcgcg
     7021 atacagccat agcctgtgtg gctggcaatc gttgggccta atggataaag tttcacatct
     7081 ttcatcttta tctgttcttc caaaagccgt tttgccttct ccgcgctctc taggtcccca
     7141 gcgtaagcca cataaacgat ttgatcaagt ggtgcaacga ttgtttttac cgtctcattg
     7201 acgattgtct ggatcgactt gtttcttcct cgaactttgt caacattcgt cagccttcct
     7261 tctttatcca ccgtaataat aggctttaca ctcaatagac tgccaagagt agcacttgct
     7321 ttggaaatcc taccgcctcg ttctagatat ttcagatcgt ctactgttac ccatgaatgg
     7381 actttcaaat aattaccttc cagccactct agggtttctt cgatgctttt accttctttt
     7441 ttcaatctta cagcttccaa tactaaaagc ccttccccaa tacttgcagc ttttgtatca
     7501 aaaacataga tctcagggtc ttcatattct tccttcagca attcaaccgc ttgaagcgca
     7561 ctactgtaag agccgcttaa tccactggaa aaagccacat ataaaacagg aatctgtttt
     7621 tccgcataag aacggaaaaa ttctaaatat cggccaacat tgatttgtga tgtcgtaggc
     7681 atcgcaccat ttttcagctg attcatgtag cggtcataat tgaatgtctt tccgaggtca
     7741 tctactaact cttgatcatt caattggaga ttcattgata aaaaatcaac tttttctttt
     7801 gctaatacat ggtatggcag atcacaacaa gaatctgtta caatttgata cacatttttc
     7861 aaccccttct cgttacattt tacccttatc gtctattata gcaaatctct tgcgctagac
     7921 acactttaac cggtttattt tcgcaagttc taatcaaaat aagaggttgt gacagaagtg
     7981 gtcagcttca agaaataaga aggaatttac gaaaattgct tctcaaattt ttgtgaaatt
     8041 tcggcttatt tccgtagaag ctacttctgg aacaccgtga atcagaggtt gtgaaatcag
     8101 cgttttgacc tgagtattag agaaacaaac ggcaaaatag ttcctcatat tttgccgttt
     8161 tttgagctaa taccgagggt cagctgattg aacaccgttt accaagaggt tgtgagcctg
     8221 ccgtttagct ccgagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttgttgaat
     8281 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttagtggaga ggttgtgaaa
     8341 aagctgctct gcatcaagca gtaaaaacaa tcagataaaa atagcactcc atatttttca
     8401 tctgattggg cttagtgccg tagatgcaag cttttgaaca ccgtttgttc gaaaaaaggg
     8461 actgtgacac ggttttt
//
LOCUS       DADVXB010000122         8396 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.125, whole genome shotgun sequence.
ACCESSION   DADVXB010000122 DADVXB010000000
VERSION     DADVXB010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.125"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..626)
                     /locus_tag="KB902_002229"
     CDS             complement(<1..626)
                     /locus_tag="KB902_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HBB6809015.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPR"
     gene            complement(849..1880)
                     /locus_tag="KB902_002230"
     CDS             complement(849..1880)
                     /locus_tag="KB902_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809016.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(1887..2717)
                     /locus_tag="KB902_002231"
     CDS             complement(1887..2717)
                     /locus_tag="KB902_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6809017.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(2714..3529)
                     /locus_tag="KB902_002232"
     CDS             complement(2714..3529)
                     /locus_tag="KB902_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6809018.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(3526..4350)
                     /locus_tag="KB902_002233"
     CDS             complement(3526..4350)
                     /locus_tag="KB902_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBB6809019.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(4340..5440)
                     /locus_tag="KB902_002234"
     CDS             complement(4340..5440)
                     /locus_tag="KB902_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6809020.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            5618..6403
                     /locus_tag="KB902_002235"
     CDS             5618..6403
                     /locus_tag="KB902_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBB6809021.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            6436..6819
                     /locus_tag="KB902_002236"
     CDS             6436..6819
                     /locus_tag="KB902_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6809022.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            6895..7026
                     /locus_tag="KB902_002237"
     CDS             6895..7026
                     /locus_tag="KB902_002237"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6809023.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            6995..7231
                     /locus_tag="KB902_002238"
     CDS             6995..7231
                     /locus_tag="KB902_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6809024.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(7309..8280)
                     /locus_tag="KB902_002239"
     CDS             complement(7309..8280)
                     /locus_tag="KB902_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBB6809025.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         2421 a         1967 c         1661 g         2347 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gattggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtgactgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaattgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      361 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      421 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      481 tgttcacaat aggaaggaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccaaaat caattctacc
      781 ttagatgttc ttatatcact ctatcagtcc tatttgacaa agagccagaa atgtttgccg
      841 actatacact agctttgttg tgcaaaatgc tgagtatcaa tttccacagg gattgctaga
      901 atatctttca gctgaatgta taaggcatcg ctaattttct cttcccgatc gttcaaccga
      961 tccactaaaa tttctttgcc ctccagcgtt tgaaaaacat accgttgaat gttgcctaaa
     1021 ataaatgatt ccttccatag aaccggaatc ttaaccccct gaggaaccgg ttcaaattga
     1081 atcagctccg gtcttaaata ataaatgcag cgattgccct tagcggaaaa ctcgtgggta
     1141 tactgattca gctcatacca ttcgaaacga ttatagttgc cgataaattc cgcaacaaat
     1201 cggctctgag gattctgata caattccttc gaggtggaaa cctgagccac ccgcccagct
     1261 tccatcacaa aaatccgatc actgattcgc atcgcctctt cttggtcatg agtcacaaaa
     1321 atcatcgtca tccctagcga ttgctggata gcgcgcaaat cccgctgcag ctgttttcta
     1381 attcgggcat ccaaagcact taatggctca tccagcagca ggactttcgg ttcagtgacc
     1441 aatgagcgag ccagtgccac ccgttgtcgt tgaccgccag aaagaaactg gacattttta
     1501 tctgcctgct ccgtcatatc caccaatgat agcatctcaa aaaccttttc ctgaatcacc
     1561 tcaggactca gcttctttac cttcaaacca aaggctacat tttcaaaaac agtcatagtt
     1621 ggaaacaatg catactgttg aaaaacaaag ccgatattgc gatccttcgt aggcttatcg
     1681 gcaatattct cattgtccag cacaatctca ccgctctttg gttgttccaa tcccgtgata
     1741 cagcgcagca acgtagactt tccgcacccg ctgggaccta gtaaagtaac cagctcaccc
     1801 ttttcaatct gaatttcatc aatagctaaa atctgttttt catcaaaaaa cagattgaga
     1861 tcatgtattt ctaaaaacat tttccgtcac aactccttta agggcttctt tttcgactgc
     1921 ttctcttccc tcgtctgctt aagggacagc tgttgctttt gtcgataagt cagcataaag
     1981 gtagttaaag caattcccac cataaacagc aaatacaaaa ccatcacagc gctagccaaa
     2041 tggccgtttt cgttcatccg ccgcagcata tagatgcgta ccgtctgaaa tcgaccgcca
     2101 atcaacaggt tcgtcagcat gtactcccca aaaaccgaag aaaaaatcat cagagaaact
     2161 agggtcacac cgatacggat gtttggaaac agcacctgga taataatcgt agacatcggg
     2221 gcgcccaagg tttctgctgc atccactaat tccttcagat taattaagcg catctggttg
     2281 ttaagactaa gatagacaat cggcaacgcc gtaataaaca atgcacctac caacactaca
     2341 aacattggga taccagtttc agcatacgtt cgaagcaaag ccgttaccaa aatcactcct
     2401 ggtaaagcat acggcagcag gagcagcttt tccagccaac gattcaaacg agggaaatac
     2461 aaatgaatcc aaataatggt gggaatcatc aacaacagaa tcgtcaccaa gaccacacct
     2521 gctaataaaa gtgagcgacc caccgcagca ataaattccc tgtccgtcag cagctgttgg
     2581 aaccattgca aggtaaaatc actaggtaaa agcgattttg accatttagt ggagctggca
     2641 tacaaaatcg ttccaataat cggcagcaag taatacagga caaagcagaa caaaatcggt
     2701 tttattaact ttttcacgtc tgcaccacct tgcctttctt ttgaataatc aacattgccg
     2761 ttaccagcag gacacctaaa gcgactgcca acgcactgcc taaattaggc ttggcgaaca
     2821 catctcccga cactaaagcc gcaattcgaa tcgttaaaag atttacatta ctgctggtca
     2881 gggcatacgc tgtttcatag gtccccatgc cattagcaaa taagatgaca aaggtgctgg
     2941 caatcgatgg tcgcaaaaaa ggcaaagcca ccttgaacca agcatacgct gatgaagcgc
     3001 ccagcaattg tgcggactcc agccattcct ttttcacttc cttcatgctg ggatacaaaa
     3061 acaagacccc taacggaatt tggaaatagg tatacgtgat ggtcaatccc caccaagaat
     3121 acaaattgaa gtccgctaga aatggcaaaa tcattttcag cacacctaca ttccccaaca
     3181 aaataataaa agagaatgcc agcggaatcc cagcaaaatt agctgccaaa ttggaaacaa
     3241 aggtgatttt ctcctgcaat ttagtcgata gattcattaa gcataaacat aaaataaacg
     3301 tcccgattaa cccaatcaca ctggagctga cagcaatcag tacgctgtta acaaaggcct
     3361 gtgtgtaata tttgttgctg aaaatatcac tgtaattggc caatgtccac tggttagtta
     3421 aatcactgtg caagctgcac agaaccataa aaagcagcgg cagcagtaaa aatgcacaga
     3481 agataaagga ggcaggaacc agaaccaagc gttttttcat ctctttcatc ccctcatcaa
     3541 ttcttgaatg tcctgcattt tctctgacgg tgcaattcct aataaccagc aaaacaatgg
     3601 agccgccagc agctgtggta cagtttgttc cttcagcttt tggcgtttat ttgaaatcaa
     3661 ataaaaagga acttcacgat gtgcagccaa gctgccgcca tgcagtccgt gcgcatccat
     3721 cccgtgatcc gcagtcacca cgacttgata acctttttgc agccattcag gaaggtaaat
     3781 agccaataat ctgtccgcct gattaaccgc tgctgcatat tcatgagaat cggcggtaaa
     3841 tttgtgaccg acatcatcaa tattcatcga atgtacgacc aaaaagtctg gctgatactg
     3901 attcactaaa taatgggcat ccgcaaataa atgcgaatca gggtaagtgt cctcactata
     3961 aaagatgcca tgctgaatca gtcgctcctc ctgatgctgg atgcgatcaa ccaaacgatt
     4021 atagggggct tgattgtaca actcgctgta ccagtggtaa gcggcggctc ctgtttttcc
     4081 gccagcttcc ttaactaatt caaacagcga ccactctttg gatcgctgag catggtaatt
     4141 actatagatg ccattttcat aggctggaac gccggtcatc agtacttcgt ataacggacg
     4201 tgaattgctg ggcagctcac tttttacctt caataagctt gcttgctggt gctcaactaa
     4261 atgattcatg aacccaagct gggcgacggc tgtgtcgtag cgacagccgt ctagtataac
     4321 tacaatcagt ttgtcaagtc tactttgcat aggtcagtac ctccgcctgc caaagctctg
     4381 gaagctctac agaggtcttg ttccaagctt cattgtcttc aactggcacc gccgcttcat
     4441 aagcatcctc cggcagtaat ttttcagcta cttctttagg cagctctacc ttgcgaatag
     4501 gtcgcgcata gccctttgcc aaattgattt gcccttcatc agataaaata tattcccgtg
     4561 ctagctttgc cgcattggga tgaggggcat ttttattgat taaggttgta tacccgctaa
     4621 tgatggagcc gtctgttggc acagttacct caaaacgctc ggagtcaatt tggtcacgat
     4681 aatttagtcc attgaagtcc caaacaactg ccacatcgat ttcacctttt tcaagatttg
     4741 ctacgctggc atcaacggtg gacaaacggc ctttttctgc catttttttg tagtaattca
     4801 gacctggctg aatatccttt tcgtcacctc cgttggcaat cgccgcagcc aatacagcaa
     4861 attgtgcttg gttggcaatc gtcacatccc ccacgctaac ttgatagtca ccctcttgca
     4921 gctccttcca gctagtcggt gcttgcttca cattctcttt atcggtgata aaggaaatgg
     4981 ttcccgtata gcttaacaac caatccccat catcatcctt tgcccaatcc ggaatttcct
     5041 cccaatagtt ggtcttataa ggtaaggtta actctttgct ttcagccaac ggaccgaagc
     5101 tgataccgac atcaccaata tcggcggttc cattttttcc ttctgattca aacttagcca
     5161 attcttctgc actggacata tccgtatcca cgtgacttaa gccgtattct ttttcaaggt
     5221 cgttccaagt gcctacccaa tttgcccaag tatccggcat tcccaagctg gcaatctctc
     5281 cttcttcctt ggctttttct ataatcgtat ctaaagagtc gtctgccgca gccgattgct
     5341 tcgttgcttc acctgagccg cagcctgtca gcaggatact tactgttgct gcacaaaata
     5401 aaccgatagt catgttacga attttttcat tcattttcat tcattcttct cccctttcga
     5461 taattccatt ctaacaaagc tttgtaatga gagaatcagt ttcttgaaaa ggtttcatga
     5521 acaatgtaaa ggttgtatat ggtttgtaaa tttcgacgaa ttcccgttaa ccttctaaag
     5581 cttttgcggt atgatagtag aaaaaaggag gctccctatg cagtattatg atcagcatct
     5641 ccacacgtat ttttcctttg attcagagga aaaatttgaa aactatttag cctatcagcc
     5701 ggagtttttc gtttctacgg atcactttga tttaaacaat ccatctaccg gaaaagatga
     5761 cattccggat tatccagcct atataaacaa actggactct ttaaaagaaa cctattccac
     5821 caaatttctg cgaggtatcg agattggcgt tgttccagga caagaagagc ggatcgtgga
     5881 ttacctcgct cagcatcctt atgatttaaa gctggtaagt attcatcaaa atggccgctt
     5941 tgattatatg gacgatgtgg ttttaaccaa agatcccatt caaactacca aggaatattt
     6001 tgatcagatg ttgcaggtct tgacggattt tccagaagga gatattttga ctcactttga
     6061 ttatggatta cgccgcttca ccttcacagc ggaagaattc gcggagcatt ttgaggctca
     6121 gctgctaacg attttcaaaa aggttgttga acgagaattg gcgatggagt taaatgccaa
     6181 gagcttcttg aaatacggca acgaagacct ttaccgttat gccgttcctt tgtatcaaag
     6241 tgtcggcgga aagctcttta ccttaggctc ggatgctcat gttgccgaag attatcagct
     6301 gggctttaaa aaaatgagtc agctgttggc agactgtcag gtagaaaagt tgctagtcat
     6361 tcaaggaaaa gaacgccgcc tgacgccgct gccgattttg tgattcctat ataatagaag
     6421 aaagtggtga aaaaaatgag caacctgtgg gactacaatc aagaggcacc catccattat
     6481 ttaattgcgc gacattggga tgcgttgaaa attgaggcgg tttgccgatc cttgttagca
     6541 gccgttccaa aacaacaact ggaaaatttt ttggtggctg acagcttgca gcgggaaaaa
     6601 gttcaggctt attttgcagc ctttaaagat cagcctttgg aatatttgca tgcgcagttt
     6661 catctttttt atcaagtagc cgccccagat gactacaacg atttacgagg acagctgcaa
     6721 ttgacctttc aagcggatga aaccgcctat accgttttat tgggaatggc tcgccttggt
     6781 gatcaggcga aggtcgagtg gcggattttc gatatttgat ggcaggatca aggcgtttca
     6841 gttgcaaacc ttcctctctt tcaattagaa aaaccgcagc aggaagaagt ttgtgtgctg
     6901 gtcaccgatg ctggtgaaat tcgtctccgc ttatttcctg accaagctcc cctggctgta
     6961 gccaactggc gctccctagc tgagcaaggc gtttatgaca acacaccttt cggctcgtgt
     7021 cattaaggaa tttgttattc aaggtggcgc tttggatggt tctggtgatg aagctgtttc
     7081 cagctatgag ggctttttcg ctgatgaagt gcatcgcgga ctttatcatt ttaatggcgc
     7141 cttggcctta ggggaccacg gcccccacac caacggcaac cagtttttta ttgtgcaaaa
     7201 cacaaaggcg caggctgacc tgctaatgta aagcaagcat acttggagct tggaggacta
     7261 ccggagctgg atggtcgtta tactgttttt ggacaggtat accaagggtt agaaatcgta
     7321 gcagcgatcg cagctcagcc gacaaacagt gaagatgtac cgattgagcc agtgttcatt
     7381 cgacaaatta acttcgaaaa aacatcgtaa aaagacactc actgacttca gcaaaagctc
     7441 tattcttgag ctggctgcag ctagtgagtg tctttcattt atccataaga taaagcttgg
     7501 attcaataaa taaataaatg ttttggttaa agctgtgacc agcaaatgag gaaccgtgcg
     7561 agccagttga tctgccaatg caaacatttc tttaggtgaa ggcgctggcg tgtctgccaa
     7621 cggatactcc agtcccaatg cttggtaacc gtgcatacca tagcagtggt acggtagtaa
     7681 ttctaacggt acgaaccgat caagatctgc cacaaaacaa gcaatcgtca gcagctcggt
     7741 caggttcata ttgatacctg gaaccacagg aactcgaatt cgcacttcgc agttaggata
     7801 ctcaattaaa aagcgacgaa tattcttcaa aatttgttgg ttatctaagc cggtccattg
     7861 tttgtggagc ttgctggtaa acatttttac atccacaaac aatgtatcca catagggagc
     7921 taccttttgg atttcattat aagcaccaca aaagctggtt tccagtacgg tattgattcc
     7981 aatgtatttc gatttttgca aaatttcttt agcaaaatcc gcctgaacca gtgcctcgcc
     8041 tccgctaatg gtcactccgc catccgagtg aaagtaaaaa acagcatcct tctcaatctc
     8101 atccattacc tcttcagcgg tcatggtctg gccaaatcct ttttcaatct gcttgctttg
     8161 tgattcggga atcgaacacc aggcacagcg taatgggcag ccctttaaat aaacaacggt
     8221 ccgtaaacca gcaccatcat gtagagaacc ctgttctatt cttaatactg ttccttccat
     8281 atagattttt gaattacaca ctagtttaaa ctaaaacaca caaggaaaaa cttaccattt
     8341 aatcataaaa ttagctcata taaatatact aggatgtaaa atagactggt caaaat
//
LOCUS       DADVXB010000123         8376 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.126, whole genome shotgun sequence.
ACCESSION   DADVXB010000123 DADVXB010000000
VERSION     DADVXB010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.126"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            57..2666
                     /gene="clpB"
                     /locus_tag="KB902_002240"
     CDS             57..2666
                     /gene="clpB"
                     /locus_tag="KB902_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBB6809026.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2817..3503)
                     /locus_tag="KB902_002241"
     CDS             complement(2817..3503)
                     /locus_tag="KB902_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809027.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(3481..3975)
                     /locus_tag="KB902_002242"
     CDS             complement(3481..3975)
                     /locus_tag="KB902_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6809028.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(3995..5215)
                     /locus_tag="KB902_002243"
     CDS             complement(3995..5215)
                     /locus_tag="KB902_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6809029.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5362..7197
                     /gene="lepA"
                     /locus_tag="KB902_002244"
     CDS             5362..7197
                     /gene="lepA"
                     /locus_tag="KB902_002244"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBB6809030.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(7291..>8376)
                     /locus_tag="KB902_002245"
     CDS             complement(7291..>8376)
                     /locus_tag="KB902_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6809031.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         2686 a         1607 c         1688 g         2395 t
ORIGIN      
        1 tttgtaaaga tcaaagaaat aagtgatctt acctttaatt aggagggtat acctgtatga
       61 atattgagaa aatgactacg acgcttcaag aagcgattgc tgaagctcaa cagattgcgg
      121 tcactcgaaa acatcaagat atcgacattg cccatgtatg gaaaatcttt ttacaatcta
      181 atcattttgg tcgaaatttc tatacggatg ccggattgga tgtcgaatct tttgaacatg
      241 aaattgatcg tctactggat gagtatccag ttgtttctgg tggaaacgtc caatatggac
      301 aaaacctcag ccagaatttc tttcgattat tgaatgaagc agaccaaata cgtgaaagct
      361 tcggcgacga gtttctttca acggaagtcg ttattttagc gttgatgaaa ttaaaaaatt
      421 atccgttaac tgtttatttg aataaaaacg gattatctga aaaagaattg cgtaaaaaca
      481 tcgaagagat gagaggagga gaaagagtga cctcacaaaa ccaagaagaa caatacaaag
      541 cattagaaaa atacggcgtt gatttagtac agcaagtcaa aagcggaaaa atggatccaa
      601 tcatcggtcg tgatgaagaa atccgtgatg tcatccgtat tctttcacga aaaacaaaaa
      661 ataatcctgt tctgatagga gaacccggtg tagggaaaac ggcaatcgtt gaagggcttg
      721 ctcaacgtat cgtacgcaaa gatgtgcctg aaaatttaaa agataaaacg attttttcat
      781 tagatatggg tgcattgatc gctggagcaa aattccgtgg tgaatttgaa gaaagactaa
      841 aagcagtctt gaaagaagtc aaaaaaagtg atggacgtat cctcttgttc atcgatgaaa
      901 tccacaatat cgtaggggca ggaaaaacag aaggaagtat ggatgccgga aatctgttga
      961 aaccaatgct tgctcgcggt gaattacatt tgatcggtgc cacaacttta gatgagtacc
     1021 gtcaatatat ggaaaaagac aaagcgttgg aacgtcgctt tcaaaaggta ttagtcaaag
     1081 aaccaacagt ggaagatacg atcagtattc tgcgtggatt aaaagaacgt tttgagatcc
     1141 accatggtgt taacatccat gacaacgcat tagtagcagc agctacttta tctgaccgtt
     1201 atattactga tcggttctta ccggacaaag caatcgattt gatcgatgaa gccagtgcaa
     1261 cgattcgggt agaaatgaac tctatgccaa cggaattaga tcaagttact agacgtttga
     1321 tgcagttgga aatcgaagaa gctgcactga aaaaagaatc agatgatgca agtaaaaaac
     1381 gcttgaaaaa tttgcaagaa gaattagctg aacttcgtga agaagcaaat gcgatgaaga
     1441 tgcagtggga aacagaaaaa gaagaagtca attctgtttc agcaaaacgt gctgaaatcg
     1501 ataaagcaaa acacgaatta gaagatgcag aaaataacta tgatttagaa cgcgctgctg
     1561 tattgcgtca tggtacgata cctcaattag aaaaagaatt gaaggaatta gaagctaaag
     1621 caaaagacag cgagattaag atggttcaag agtccgttac cgaaaatgag attgctcaag
     1681 tcgttggcag attaacgggt atccccgtaa cgaaacttgt agaaggtgaa cgagaaaaac
     1741 taattaaatt gaatgaaaca cttcataaac gagtgattgg tcaagatgaa gcagttgatg
     1801 cggtcagtga cgcggtaatt cgttcacggg ctggattgca agacccaaat cgtcctctag
     1861 gttctttcct tttcctagga ccaactggtg tcggaaaaac cgaattagcg aaagcgttag
     1921 ctgagaactt gtttgactca gaagatcata tggtacggat cgatatgagt gaatatatgg
     1981 aaaaacatgc tgtgtctcgt ctagtcggag ctcctccagg ctatgtaggt tacgaagaag
     2041 gtggtcaatt aacggaagct gtcagacgaa atccttatac aatcgtcttg ttggatgaaa
     2101 tcgaaaaagc gcatcccgat gtcttcaata tcttgttaca agtcctagat gacggacgct
     2161 tgactgattc aaaagggcga gtagtagatt tcaaaaatac ggttctgatc atgaccagca
     2221 atatcggttc acagttactg ctggaaggcg tgactgctga tggaacgatt ccagaagcag
     2281 tggctgaaca agtcaacacg ctattacgtg gaaacttcaa accagaattc ttgaaccgaa
     2341 tcgacgacac gattttattt acaccattga gcctagacaa cgtgaaagga atcgttgaca
     2401 aaatggtggc gcaattggca caacgtctgg aacatcaaga aatcctgctg acaatcagtg
     2461 atgaagccaa aacgtggatt gctgaaaatg cttatgaacc agcatatggt gcaagaccat
     2521 tgaaacgatt tatcactaag gaagtagaaa caccactagc taaagaaatc gttgcaggac
     2581 atgttatgcc taaatcaaaa gtaacgatta ctttacttga tggacaactt catttcaaaa
     2641 cagaagagct agaagaaatc gtctaatctt ccattgagac tataaaagaa aaaaggggtc
     2701 tgacacaact agtgtcagac ctcctttttt caaataaaca gtgttccaga agtagtttct
     2761 tcgaaaaata agccgaaatt tcttgaagct gcccgcttct gtcacaacct cttttattag
     2821 gtatttttca ctttttctaa tttataactt tcaaagtaac gctcatcttt tttactttga
     2881 gaccatgcaa acaatcccat taaggcagca cctatcgtat ttgtcagcaa gtcgcccatc
     2941 gtatccatca atgctgctcg tccgacaaac agtgtgccat cagaagcagc aaaacgttga
     3001 agattcatgc ctaagaactg gtcgcataag aattcccaga actcccaaaa cacgccgcaa
     3061 agtccagcaa acgcaaagcc gaataagagg aacaaccaag gactggtttt tgatatctca
     3121 gcatctttca tcaagtaacc aatcaatcca tagccaagag ctgtcaggac cattggactc
     3181 accgcatgta agattttgtc ccaaaaagag atgatactga tcaaatgcat ccctgtgcct
     3241 aaaaagacag agatgaacaa gaaaaaccag taaaacaaaa cgattgctgc tggtatttta
     3301 agtttgaaaa ctttcaaaat gacttgtggc atgaaaatca atgcaatccc taataaagat
     3361 tccacgataa atgtgattcc ttgagaagtc gaatattttt gtgtgataaa ttcataaaaa
     3421 ttatagcaga caacgaatac accaaaagca agtaaagcta tttgcacctt tttgatttct
     3481 ttaatcactg aaagtccctc catctaaaaa tctttttact tctgaaagca actcaatttc
     3541 tgaagaaacc acttttccgt tcaatttgat caaacctatt gtatataagt tcaggtagtg
     3601 aaattgattt tcagctgttt cttgtagtgc agcgattttt ttcgggtggg ttccgccttg
     3661 ctgtcgagta tcagtatata agccgatcac tgggatgcct ttcgcataag ccacaccgat
     3721 ttccgatgct accccggcat cgatcgtcag cccatctagt aaagcaatca ttaaatcact
     3781 agccaacact ttttctgtgt cagcaagagc aatcattcga ctgtctgcat aagcagtttt
     3841 gtcattgatt gcttcatttt cttgaggaag atagatcgaa agctcagaag agagctctct
     3901 gatttcttta actaactgtt ggttatataa caaatcactt ttagcaaaca ttggtgcggc
     3961 aaaataaatt ttcatctaaa catcatcctt tttatcaaaa ataatcgcta aagtaagctt
     4021 ccatgtttgg aatgatacgc tctagtgact tcagtgtttc ttcatctgtt tctaaccgtt
     4081 cgattcttgc caaataagaa gcacggcgat aattcatcat caagcaagtc aatgtttgga
     4141 tatccagtcg aacggatttt cctataggtt catttaagac acggacttgt ccctgttcat
     4201 cccatgttaa agcgaagaca ccattattcc aaggagcgac aggatcttca atgatgaaat
     4261 gaaaagcatc agctgttcca acaaacggaa accgttgaag gaattctttt acatcaacga
     4321 tccgagccat aaaatatggt tcgatctgct ctttgatctg actatcttca atcaaaaatg
     4381 ctaaaggctc atttttataa atatctccat gtacccagta gatcatggaa aaatgtgcgg
     4441 aaataaagtt ccataagcca tttcgagctt cttgatcaag atagaacatt tcttttacgt
     4501 gaaatatttc ttcagctacc cagtagaaca gaacacctct tggttcatgg ttgctatcgt
     4561 agtagacagc ggctgtgcgc tcatcttcat tttcgaaacg ccaatactct tcccaatgaa
     4621 aatcactgcg gaataaagca ccatggtttt gttgggcaaa tttgtcataa acggaaaata
     4681 cgtctggatg atcaactggt aatcgctcaa ccataccact tactgggatt tgtttaggta
     4741 gctgtgtatc tctgatttta aaggaaagtt tatcagacat gatttcccat cctttacgcc
     4801 gatagtaggg gatactgtaa ggatacaaat aagagatcca ttgcttattc ttgcgcatat
     4861 tatccaatgc aacgataatt agatcttgca tcaatccatg gttagcatat tctggataag
     4921 ttccaactcc agtcacacca cccattttat aacgtgcacc gtgaatattg acttcacaag
     4981 gatagatagc gatttgagag atcagtttat tttcgtggaa ccatccgaac actttcgata
     5041 cttccaaaat cggttttttg gaacggataa aagctcgttt attctcaaac ccgctttcct
     5101 cgatgtctgc ttcagtcact tggaacacat aggaaagcaa ttcattgaat tgatcgatat
     5161 gttcttgagt gaccggtttt aattcaagat tttctctaaa atctttttga tccatttttt
     5221 catctccatt tattagcttg ataacagtat agcaaaattc tacaaaaaaa acttctatag
     5281 ctgactaatt aaaaactctt taaattactg cttttcgttg gtataatgga aagtgctgat
     5341 tatatgaaaa gaggagacgc tatggatata aagaaaatga aagaacgcca agagcagatt
     5401 cgtaattttt cgatcatcgc tcatatcgac catgggaaat ctacattggc cgatcgtatt
     5461 ttagaaatga cgcacactgt gacgtctcgc gaaatgcaag atcagctgtt agactcgatg
     5521 gatttggaac gtgaacgtgg aatcacgatt aaattaaatg ctgtagaact caattacaca
     5581 gcgaaaaatg gagaaacata tatctttcac ttgattgaca ccccagggca cgtcgacttc
     5641 acctatgaag tctctcgaag ccttgctgcc tgtgagggtg ccgttttagt ggtcgatgca
     5701 gcacaaggaa tcgaagcaca aacattggcc aatgtttatt tagcgttaga caatgatttg
     5761 gagatcctgc cagtcatcaa taaaatcgac ctacccgcag cagatcccga acgtgtccgt
     5821 caagaaatcg aagacgtaat cggaatcgat gctagtgaag ctgtattagc cagtgccaaa
     5881 tcagggattg ggattgaaga tattctcgag cagatcgtgg aatatgttcc tgcaccaagt
     5941 ggagacttag atgcaccgct aaaagctttg atctttgact ctatttatga tagttaccgc
     6001 ggtgttgttc taaatgtccg gatcacggac ggtatggtca aacccggaga caaaatcaaa
     6061 ctgatgagta atggcaaaac atttgatgtt acagaggtcg gggtcttctc gccaaaagca
     6121 gttgctagag actttttgat ggtcggtgat gtcggttata tcacagcaag tatcaaaact
     6181 gtccaagata cacgagtagg ggatacagta acgttagcag acaatcctgc cgctgaagct
     6241 ttaccaggtt accgaaaaat gaatccgatg gtttattgtg gtctttatcc aattgatact
     6301 tctcgttaca acgatttgcg ggaagcttta gaaaaactgc aattgaatga tgctgcttta
     6361 caattcgaac cagaaacctc tcaagcatta ggttttgggt tccgctgtgg attcctcgga
     6421 cttcttcata tggatgtcgt ccaagaacgc ttggaacggg aattcaatct agaattgatc
     6481 acgactgcac catccgttat ttaccatgtt aataaaacgg atggtacgac tgctacagta
     6541 gataacccgg cagattttcc tgaacctgta acgattcagg atgtagaaga accattcgtc
     6601 aaagcacaga tcatggtccc aaatgatttt gtcggtgcag taatggaact ttctcaacga
     6661 aaacggggag aattcattac gatggattat ttagatgatt accgagtaaa tgtcgtctat
     6721 aatattccgc tttctgaaat tgtctttgac tttttcgaca aattgaaatc aagcacgaaa
     6781 ggctatgcct cattggatta tgaaatgtct ggttatcaaa aaagcaagtt agtgaagatg
     6841 gacatcttgc tgaatggaga aaaagtcgat gcattaagct ttatcgttca ccgagacttt
     6901 gcctatgaac gtggaaaagc aatcgttgaa aaactgaaaa aactaatccc acgccaacaa
     6961 tttgaggtgc caatccaagc agctattgga caaaaaatcg ttgcccgttc agacatcaaa
     7021 gccttgcgta aaaacgtctt ggctaaatgt tatggtggag atgtttctcg taaacgtaaa
     7081 ctcttagaga aacaaaaaga agggaagaag cggatgaaac aaatcggctc cgtcgaagtt
     7141 ccgcaagaag ccttcatggc cgttctgaaa atggacgagg acgaaccgaa gaaatagcaa
     7201 gggtttgttt gaaaacagtg taaaaaataa accatgttta catggatttg ccaccggttt
     7261 gccaccggtg gtttttttcg gtggcaaaaa tcaagaattc tttctaagat tttccatgat
     7321 atcgaccgtt tcatttctca tcttatctgt tacatgcgag taagtatcca tcgtaattga
     7381 aattctgctg tggcccaatc gttcagagat ttctttcatt tttgcgccat tttcgagaag
     7441 aagtgtagca tgagtatgtc tgagagaatg gaagttaaaa gagagggaga gtgcattcga
     7501 tatcctccta gtattccatt tcactacact tggcgtaact agctcaccgt cttccttcgt
     7561 acatactgca tttgaatcaa tgtagagctt tccatacttc attcgatttt ctaattgttg
     7621 tttcttatgt tttttcagaa ttgctagcaa ggtttgtcca ataaaaatcg ttcgattgga
     7681 actgcttgtc tttggcgtac catataccca tgcgccgtca ttctttacca tttgtttctc
     7741 tacagtaatt gttccatttg aaaaatcgac atcatcccac gtcagaccac aaacttcgcc
     7801 aacgcgcatt cccgtataaa atccaatatt caaaggaata tagaaaggat gtccttcagg
     7861 agtaatttct agcatatgat caaagtcctc aagagaaatg atttttagat cttttttagt
     7921 cgttggtcgt gcttcatatt ttggtatttt tacatacagc ataggatttt gcttgattaa
     7981 tccccaagga taaaccgcca tattcagcgc attcttaagg acagagtgag taatagtcat
     8041 tgttttcttc gagtaaccct ttttaaattc agcattgatg aaattttgta aaagagcagg
     8101 ggagagatcc gtaagttttt tctttcctaa ataaccgttt atatgatttt tgatggtaaa
     8161 tcggtagttt tcataggtat tgtattttag atttagttta acgtattcct ccatccaaaa
     8221 atcaaggtat tgttttactc gagtatccgt acctaaaaag tattgtcctg tttcgtcaat
     8281 atctgataaa acttttcgta aagcagcttc ggcctctggt cgggtgtctc cgccaacttt
     8341 ctccactttt tttcttgagc catcatcatt gatatc
//
LOCUS       DADVXB010000124         8161 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.127, whole genome shotgun sequence.
ACCESSION   DADVXB010000124 DADVXB010000000
VERSION     DADVXB010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.127"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            24..1316
                     /locus_tag="KB902_002246"
                     /pseudo
     CDS             24..1316
                     /locus_tag="KB902_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1835..2569
                     /locus_tag="KB902_002247"
     CDS             1835..2569
                     /locus_tag="KB902_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6809032.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            2585..3754
                     /locus_tag="KB902_002248"
     CDS             2585..3754
                     /locus_tag="KB902_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6809033.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            3770..4765
                     /gene="lacD"
                     /locus_tag="KB902_002249"
     CDS             3770..4765
                     /gene="lacD"
                     /locus_tag="KB902_002249"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6809034.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            4844..5770
                     /locus_tag="KB902_002250"
     CDS             4844..5770
                     /locus_tag="KB902_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6809035.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            5789..7039
                     /locus_tag="KB902_002251"
     CDS             5789..7039
                     /locus_tag="KB902_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6809036.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDANRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
     gene            complement(7376..8161)
                     /locus_tag="KB902_002252"
                     /pseudo
     CDS             complement(7376..8161)
                     /locus_tag="KB902_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249826.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         2648 a         1355 c         1653 g         2505 t
ORIGIN      
        1 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gccgaaaagt
       61 tagctgaatc cattctgaat gcctatcaac ctgaatctgt cgatgacatg caagatgctt
      121 tgaaagatgt gtttgggccc ctttttgaaa aaatgcttca aggagaattg aataatcatt
      181 taggttatga tgcccattct aaagagccta aggaacacga taaccgtcga aatggctatg
      241 gaactaaaac gcttaaaacc agttttggtg aagtagctat tgatgttcct agagaccggg
      301 aagcttcctt tgaaccagag ttaattccta agagaaaacg agatgtctcc gacatcgaag
      361 ggaaggttct ttccatgtat gcacgaggaa tgagtcaatg agatattgcc gcaaccgtcg
      421 aagctattta tggctttgat atttcccatg aaatgatttc agatatcact gacgctgtcc
      481 ttcctgaatt ggaagaatgg caagcccgcc ccctagcaaa gtgttatgcc tttctattcg
      541 ttgattgtat gtatgttact ttacgagaaa attatgaagc caaagaatat gctgtacaca
      601 ccattcttgg ctatgatctc aaaggaaata aggagatttt aggattatgg ttaaatcaaa
      661 cagaatctaa aaatcgctgg atgcaagtat ttgatgaact gaaagcacgt ggtgtcgaag
      721 atgtcttttt catttcgatg gacggtgttt ctggcctcga agaaggcgca aaagcgatct
      781 ttccatcggt aattgttcag cgctgtattg ttcatcttgt tcgaaatgca ttgcgctata
      841 ttccaagtaa ggactataag gaagtctgcc gagatatgaa aaagttctac ggtgcttctt
      901 ctctaaacgc tgcacatgct gcttttgaca gttttcaaaa tcggtggtct cattattctg
      961 gtgctgtaga tgtctggaaa cggaactttg cacatgttga acaactattt gattatggta
     1021 gtgccattcg aaaaattatg tacactacca atgcggttga aagtgtccac tccagcttca
     1081 gaaaagtcac aaaaaaagga gcgttctcta atgagaatgc actcctaaaa ctactttatt
     1141 tacgcacgaa agaattacac gcgaagtggt caggtggtcg aattcaaaac tgggctatgg
     1201 tgcttaatca gttaatgatc aacgagacct tctcctctag aatgaaaagt atgcgattta
     1261 ccttccgtaa caacggtagg tttattcaac tatgtgtccg atcaaaattt atctgatttc
     1321 aaaatagccg agagaattat ggtggttaaa aactcttaac tatttaactt ccacagttta
     1381 gttgacaaac ccacttaatt ctgataacga aaaacatatt cgaatgatta aacagaagta
     1441 aatacttatt taaataactt ttaattttca tgttcataaa tgatttgaaa ccaaagcaaa
     1501 tgcgttgcac ttttcctccg tcttccgaaa atcgttcaat tcactggtaa gtagtcattt
     1561 gatagtttga ggcaaattgt tgattgatga agggtaggag ctaaaaaaag ataccagttg
     1621 aagagagaaa aagaaaaaaa tagagggtgt tcttgaatga aaaaagttgg aaaattattt
     1681 ttcatttcct tttattccta ttaaaatcag tgatgtcaat catattaaca agactaaaaa
     1741 tgaaaataaa aaaaagattg ttcttagtat tgactcataa aaaataccac tactatactt
     1801 acattgtggt tatagccagt taggagagac atcgatgcaa aatacctttc aatcaaaatc
     1861 actttattat cagctggtag aaatattgaa acaacgaatc gaaaacagta tggtcgctca
     1921 tgacaagctg ccatcagaaa gagagttgac cagtttttat ggcgttagtc gcacgacggt
     1981 gcgactagca ttgcaagaac tggaaaaaat gggctacatt tatcgacagc atggaaaagg
     2041 aacctttgtt tcggaattaa ggacaaatgc gactgatcta gctggcgcat atagttttac
     2101 cgaacaaatg cgggcaatgg gcaaacatcc tgaaaccaag atattggcct tcaagaagat
     2161 tgaagcaact aaatatttag cgagtcatct gaatgttcaa ctaggtgagc ctttatttca
     2221 attagaccga ttgcgcttag ctgatgattt gccaatgatg atcgagaaat cctatttgcc
     2281 agtgaagcta tttatgtccc tttctcaaga aattctattt ctgaaacctt tatataattt
     2341 gttttcagag aatttcaatc aaatcgtacg gttggctgac gaggaatttt atgccagcat
     2401 tgtccagaaa gaagatagtg agttgctaaa tattccagaa ggatcaccag tgctccattt
     2461 agttcgctca acctataatc tcgagaacga agtgattgaa tttacattaa gtgtagcgcg
     2521 ggctgataaa tttcattata agatcaggca tctgcgttcc actaactgaa ttggaggaaa
     2581 gaaaatgttt atgttctcaa aagaagaact acgaaagcta ggagcagaaa atactacccg
     2641 agaaattcga caacaaccgg aactgtggca tgagacgttt gaccgttatc aagaaacagt
     2701 tgcagattta gatcgtttgt ttacggatgc gaaacaacat gctggagagc gaccaatccg
     2761 agtcattttt acaggggccg gaacctcgca atatgtggga gatacactaa ttccgtttct
     2821 tactagtcaa ggaaatacga accagtttat ttttcaaagt attggttcga ccgatatcgt
     2881 tgctacgcca aaagaatacc tgattcctga tgagacaacg atcttggtct catttgcccg
     2941 tagtggaaat agtccagaaa gtctagccgc agttaagatg gccaatcagc tggtcaacaa
     3001 gatctatcat atcgtgatca cctgtgcacc agacggatta ttggctacac aaatgcctac
     3061 aaaaaaagaa aatctagttt tactaatgcc aaacaaagcc aatgacgctg gttttgctat
     3121 gacaagcagt ttcagctgta tgacgctgac tgcgctactt atttttgatc aagcaagcaa
     3181 tcagcaaaaa gaaagatatg ttcatcaatt aagccgacta ggagaagaag tcatccaacg
     3241 agaatcagag atccaagggt atctggcatc agactttcat cgcatcattt acttaggttc
     3301 gggaagttta ggcggattga ctagagaagc gcaattaaaa gttctcgagt taactgctgg
     3361 aaaaatcgca accgtatttg atacatcttt aggattcaga catggtccca aatcttttgt
     3421 caatgagcaa acattggttt tcctgtttgt cagcaatgac tcatatacgc agaaatacga
     3481 tgtagacatg ctggaagaaa tcaaaaatga cggtattgcc caacgcgttg ttggaattgg
     3541 tcaaaagggt tcattgttta gtggtgattc ctttgaatta gttgcagatt cgttactgcc
     3601 ggatggctat cttgctttag cagatatcat ggtagcccaa acgatcgcat tactttgttc
     3661 ggtgaaggtt ggtaatacac cagatacacc atcgccaagt ggaacagtca atcgtgtggt
     3721 caaaggcgta acgatttatc catatgaaaa ataggaaaga gtgtgaagca tgttagaatg
     3781 gtcggaaaat aaaagacaag caatggaacg tctatcgacg ccagaaggca ttattaccgc
     3841 tttggcgatc gatcagcgag gcgcgctgaa gaaaatgatg tcggctttag ggatggaagc
     3901 gacaaaggaa aaaattgagc agtttaaaac actaatttcc caagaattga ctccttatgc
     3961 ctcagcaatt ttattggatc ctgaatacgg actgcctgct gcacagaagc gtgcagcagc
     4021 gagcggtctg ctgttggcat atgaaaaaac tggttatgat caaaccgtac ccggccgctt
     4081 gccggatctg ctgtcggact gttcagttct gcgattgaaa gagttaggtg cggatgcggt
     4141 gaaattttta ctgtattacg attatgaaga agcagaggaa atcaatcggc aaaagcaagt
     4201 ttttgttgaa cgaattggaa gcgaatgcat ggctgaagga ctgccatttt atttagagtt
     4261 attgtcatat gatgctaaaa atgtagatac gaaatcgctt tcctatgcca aagcaaaacc
     4321 gcgcaaagtg atcgaaatga tgaaagaatt ctcgaaaacc cagtataaag tagatgtctt
     4381 aaaggttgaa gtaccagtaa acatgtcatt tgttgaagga aatgcaacag gggagatcgc
     4441 ctatacacgt caagaagctg ccgcttattt taaagaacaa agcgatgcaa cagatttgcc
     4501 gtatatcttc ttaagtgctg gggtatcagc ggcattattc atggagacat tgcgttttgc
     4561 caaacatgct ggggcacgat tcaacggtgt actctgtggc agagcaactt ggaaagatgc
     4621 agtcgctcct tttgttgaaa aaggagaagc ggcaacttta gaatggctga cagaacaagg
     4681 gacacaaaac attcgtcaat tgaatgaagt gataagagaa actgccatcc catggtatga
     4741 gaaagtaagt gaaagcactt gttaatgttt ctaatatatt agtagtgata agagatatgt
     4801 gtgattataa tttatcatta ttgaaactgg gaggatattt tatatgaata aaagattgtt
     4861 agattattca gcttcagatt ttttgaaagc taagccgatg gaattaaagc aggcaatttt
     4921 ggcttctgaa ggtagaacaa ttatggcaga aaatgtgcca agtagctgtc cttacatggg
     4981 aaaatcagtg acaaatgcag aattggagag agctgctgga gctgatttaa ttttgtttaa
     5041 tgcactagat ctttttaatc ctcaaatttc aggtgtacct ttaactctaa aagagaatcc
     5101 aataatctgg attaaaaaag ctttaggaag agctattggt gtaaatttag aacctgtaga
     5161 caaagaagtt ttgatgagtg aaaatcgaac tgaaatttca agtggtagaa tcgtttctcc
     5221 tgagacttta aaaaaggcaa atgaattagg ctttaatttt atttgtttaa ctggaaatcc
     5281 aggaacagga gtatctaata gaactattga gaaagcaata acattatcca aatcaatttt
     5341 taatggatta attatcgctg gaaaaatgca tggtgctggt gttgatgaac caattatgaa
     5401 cttagatata gcaaaaagat ttattaaaac aggtgtagat attttattag ttcctgctcc
     5461 atacactgtt ccgtatttca tggaaagtga tttgcgagga atcgttgatt atataaaaga
     5521 ttttaataga aataaatcta ttgaggaaaa agttctagta ctaacggcta atggaacaag
     5581 ccaagactct tctgaccaag aaactattaa aaaaattgca ttagcatcaa aagcatgtgg
     5641 agctgatatt caacacatag gggattcttt aaatggtatt tgtcttccag aaaatatttt
     5701 tgctttgggt caagcaattc ggggatatcg tcatcaaatt attatgttag gaaaatctaa
     5761 ttatcgttaa ttaaggagga aatgaaagat gatcgacaaa gttcaaaaaa tagctgcaaa
     5821 aattagtaat caaagacatc tactagcttt aagagacagc atggctgcag ttatgccatt
     5881 aatcattatt ggttcctttt ttatgttatt agcaaatttc ccgatagaag gatttacaaa
     5941 atggttatct gaaattggag tacaatcctt tttgaacaaa gcatcagatt caacatttgg
     6001 tattattgga ttagctgtta cctactcttt gggacacaat ctagcaaaga cttatggtgt
     6061 agactcatta tcagcaggat tattatcttt gagtggatat gttttactta cacctttatt
     6121 ggatgcagat ggttctatag gatttccaac aaaatacttt ggtacctcgg gtctttttgt
     6181 tggtattatt gtagcacttg tatctacaga aattttccgg tggtttgtac ttaaaaatat
     6241 tacaattaaa atgccggcaa gcgttccacc aaatgtaagc cgagctttcg ttgctattat
     6301 tcctggcttt tttgtcgttc tactatggtt tattgttgtt gtaatttgtt ataaacttgg
     6361 aattgaaaat gttcatgctc ttattgcaga tacactcgca aaaccactat ctttactgac
     6421 gaaaacttta ccaggaatta tattggttat acttattcaa tgtttctttt ggatgtttgg
     6481 tattcatggt gcacaggtaa cggggccaat aattgaaccg ttattattgc aaaactctga
     6541 tgcaaataga attgcttatc aagctggaaa agaacttcct aacattataa cttatgaatt
     6601 cttatataac tttgtttttt ctggtggtgc aggttgttta tttgcacttg ccattttaac
     6661 atttttcttt tcaaagagtc aggaaaataa aactttaggt aagttatcaa tcgctccagt
     6721 aagttttcaa gtagcagagc cccttctatt tgggtttcca actatattaa atataaaaat
     6781 gttaattcca tttgtaactg caccagtagt aacaacatta attacttatt tttcaatgag
     6841 tatgggatta gttgcaaaac ctgtaggagc aacaatccca tggacaactc caccgataat
     6901 tgccggattt ttagcttctg gtggacgaat aagtggtgca gtgattcaag taataacaat
     6961 tgcaataaat gttttgatat actatccatt ctttaaatta gatgataatg ccaagctaaa
     7021 aagcgaaaaa aatgattaga actacctata tgtttctaac tgtagttaag tatgaaaaga
     7081 ctatttttaa atttagcatt tttgcgctat cggcgtagat gaagtatcac gataacgaaa
     7141 ttagtttctt tcatttagaa ttaaaaaatc aacttaaatt ttttctgaaa aatattaata
     7201 tcttattata aaaactaatt ttatttaagc atatttttat tagatatttg gttttttgcc
     7261 aataagtatt gatgggttgt gtaaaatcga tttgagacag aatgaacttg attttgtctc
     7321 atcgacattt agtgttggta gagaaagata caactgaaaa tttagtcata accagttagg
     7381 caaagtgttt aactggtttt tgttttactt ggatgatcaa accttgaatg agataaagtc
     7441 ttgctcgaaa gttatggaaa tttcgatagc cataggctac tcgctttatc acttttatct
     7501 tgttatttgt tccttctaat gcaccattac tatacttggt ttttaaagca tattgaatct
     7561 ctaatttgta tttatttaaa aacgttagct tcttacaaaa ccgttgtgtc aggcgttgat
     7621 ctaagctgtt gatcgtatcg aaaaagcttt ggcaatcctt gtgtttaaag tgattgagga
     7681 gaagttgaca agtctcgtaa gcccttgtta attgctcatc ataactcaaa agttcatcga
     7741 cgatcgcttt ttgctcattg gtctacgaaa ggatcgatca tactgataat tggaactatc
     7801 cagatcataa gcatgcttaa ggagtaattt ccagaatcac ctcaatcgtc gatactttgt
     7861 cggttccgtt ttttgaaagc tgttcattgt tttaattcgc aactgattta atgcacgagt
     7921 gattttttgg acaatttgaa agcgatcggt cacgattttg gcgtttggga agaccgcctt
     7981 tacaagttca aaataagggg cattgatatc catcacgacg taatttacgt tcgctcgtgc
     8041 ttttcgagtg aaattaagga aatatggttt taagaaagct aggcgtcgat tctccaatac
     8101 accgattaat tgctgggtct gcccattcat aaaaacaaaa ctcatttttc cgctgcagga
     8161 c
//
LOCUS       DADVXB010000125         8157 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.128, whole genome shotgun sequence.
ACCESSION   DADVXB010000125 DADVXB010000000
VERSION     DADVXB010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.128"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            368..931
                     /locus_tag="KB902_002253"
     CDS             368..931
                     /locus_tag="KB902_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809037.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKTRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            918..1802
                     /locus_tag="KB902_002254"
     CDS             918..1802
                     /locus_tag="KB902_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HBB6809038.1"
                     /translation="MKRFKGSRMSKKIGKESLSLGLKKEIFKFKNMYSEPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIKKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNETLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAENEFAEVH"
     gene            2299..2553
                     /locus_tag="KB902_002255"
     CDS             2299..2553
                     /locus_tag="KB902_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809039.1"
                     /translation="MYNVGDQIDEIVKIGNVKLDKSKYCISETEIIFNTELGYILIWK
                     LPFPKDEETLKKINTLKIRYCVYEVIDKNTYVINQVKVMG"
     gene            2949..4550
                     /locus_tag="KB902_002256"
     CDS             2949..4550
                     /locus_tag="KB902_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6809040.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTVFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILQ
                     TSRGRYGSTKIATSKFVEAKILSTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            4784..5083
                     /locus_tag="KB902_002257"
     CDS             4784..5083
                     /locus_tag="KB902_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6809041.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            5218..5577
                     /locus_tag="KB902_002258"
     CDS             5218..5577
                     /locus_tag="KB902_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HBB6809042.1"
                     /translation="MNIDGIYNESDFKKGDIAVIRSEYDFPSEIGIHTVEGKTVCRYW
                     GRKGNLILLLDTDSGDKLKFCFWHNTNYCCEPIPKRLIDVDKESVRYLADGTRIRLTY
                     QKSENASITRVRDIVVI"
     gene            5594..5812
                     /locus_tag="KB902_002259"
     CDS             5594..5812
                     /locus_tag="KB902_002259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809043.1"
                     /translation="MELIPYAYQHLYKAKSMKDGNEVVGALICCPPFSYIATIESMKK
                     MCVDELNDGEVKNLKLTRVLERSIEEFR"
     gene            5827..>8157
                     /locus_tag="KB902_002260"
     CDS             5827..>8157
                     /locus_tag="KB902_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HBB6809044.1"
                     /translation="MATVILAEKPDQAEKFAFALADKKIPKSGGKFEFQSEVFGDTIV
                     TWGIGHLVGLSMPEKYEWLPNKEKWDLANLPFLPKMDELKYEVSKGKSQQFAVVKACL
                     ENADQIIIATDPDREGENIAYNIFKLCKQSIFKKPMKRLWINSLVKSEIIKGFKNLRN
                     AEETISFFEEANARQIADYLVGMNYTELYTLKLQQKGLSGVVSLGRVQTPVNTLVVEN
                     DLSIKNFKSEKYKVIECHTVDREPKVIFKNSREYFNLDEFEADTKKYGLDSASIGIVK
                     SVEKTLKQVEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFD"
BASE COUNT         3094 a          945 c         1527 g         2591 t
ORIGIN      
        1 tatgatttac taattcataa gaatgaaaat agtaatattg gtagaattat aatcacaaac
       61 ttaatagtaa ttactattgg gattacaaca ttaacaaata aagctttaat atcaagtatg
      121 attttaatag tgtttgattt tattatcatt tatagtttgc tgtttttaat aaagaaagta
      181 actgaatatt taaatcgtta ggcatgaaat aaattttaat tgaggttgaa ttatagcggt
      241 aaatcataca aaatagaaat gtagtcttgt taagcgtctt gactatctaa ttttgaatga
      301 ggagggttgt atatagaaaa agggtagtta aattcgtaga tcaaaaggct acgaaggaga
      361 atatagaatg acagctattt ataaagcact aaaaaattct aacgtatcag agtacgttaa
      421 gtcgagagta ttaaataata atttagatta cattttagaa aatggtgttg ctgatttaat
      481 cagtaaatta agtgatccta tagatataga tcatttggtg gtatggcaag atggtacttt
      541 agaagtatca atatatggag aattttatag tagaaataaa gtaactacat tcaaaaatag
      601 tattagtggt cgagaagatt taaaaggaat caataaaaat agtaaattct atagaacaaa
      661 taaagaattg ctagaaaaaa tttcaaagcg tgtttttgaa ttggtgaatc cattttcaaa
      721 aacacgtagt aaagaacttt ttggaatttt ttatgatggt tttagtgcaa aaagtaatgt
      781 agaaaaattt ttttatttta atgattcagc ttatattgcg gttaaagaca gtaaaagaat
      841 ccctgaagca actttagaat atttagagcc aattaaattg tctgtttttt attcacttta
      901 tgagaaagaa atcgctgatg aagcggttta aggggagtag gatgagtaaa aaaataggca
      961 aagagtcgtt atcgctcgga ttgaaaaaag aaatttttaa atttaaaaat atgtatagtg
     1021 agccggaatt tagactcatt tttcaattag atatagtgag agggctgaaa attagtttta
     1081 gttgtttagg ttatctggtt tggctattca ttgctagagt aggatggagc aatgcttata
     1141 gcttttataa actgttcgcc ggaactgatc gattaaaaga atcattagag gtgaaagaag
     1201 ccttaaatat tttaggaagt cttgctttca gcctgtttat ttttgcttta tttatcttac
     1261 aagtaggaaa aataatgatg tcaacaaatg acaattatat taattatttg aagccttttc
     1321 aaaaaggaat aaaaatcatt tgtagacagg gcacagtttt atttctactt agcctgtatg
     1381 agcatgaaat tcattttcaa aattattata atacgacaac taaacttggt gcatttttac
     1441 tcctatattt agttagtaat atagctgaaa aaatgctgtt taaacatatt gtaaagcaag
     1501 tcttttctga tattaaaaag gaaagctatt gtttaaaaac accttatgga aatttaaaaa
     1561 atgttgagct gtttttattt aaaatggata gtaagtggga taaatatatc tatagaagta
     1621 aagaagtatt tttaactggt agttataacg aaactcttca ggagagcctg tacgacacag
     1681 gagcaatatt taataatgaa cctatggttt tgaaagattt ctttggagat tatgaactag
     1741 tttggaatcc aaaacagctt agtgaacagg gggcagaaaa tgaatttgct gaagttcact
     1801 aacatagtgt acagaaaaac attatctgaa agaagaacgc cttcaaaaga aagtataaga
     1861 acgattgggc cgtacagaag actaacgaaa gatcgtaaaa aaaaggaaag acaatgaaaa
     1921 tgtctttcct ttttttgact acaagtagcc tgaaaatgaa attccaaaag actacttgta
     1981 gtcttttgtg gcaaaaataa agagccaacg aaagctacca acaatcgttg actcgtaaga
     2041 ctgttcgtag taagaaaaat ctttggcaat ccacgaagtc tttatttcat aatttatata
     2101 aatgattata cagtcatttt cctgaatttg caagtaaaaa agctaagaaa tattgtttaa
     2161 acgtttcctt aaaagaatct ttaaataaat ttttttccaa ttgaaaacat gactacaagt
     2221 agactatttc ttttattcta agttgactac aagtagtcaa aatgatataa tatgtatatc
     2281 aagaaaggag aaacaaaaat gtataacgta ggagatcaaa tagatgagat cgtaaaaata
     2341 ggtaatgtta aacttgataa aagtaagtac tgtatttcag aaaccgaaat aatttttaat
     2401 actgaattag ggtatatttt aatttggaaa ttgccttttc caaaagacga agaaactctg
     2461 aaaaaaataa atactttaaa aatcagatat tgtgtttatg aagttattga taaaaatact
     2521 tatgttataa atcaagtaaa agtgatgggg taaaaatctt taaaaaaact cttgttaaaa
     2581 gtaattctat tagcttataa tgttggtatt agttctgaag ccaaaggaac actaaaaaat
     2641 tctagtagaa aagttagtta cagactctct actatgtatg aatgtaacga aaaaaatagc
     2701 gaaaaagata attaaataag actaccaatc ttatttaatg gaacttctgt agtaagaaaa
     2761 gcgatttggc aatccacgaa gtccaccaag atgagctacc aactcatttt aattgttgca
     2821 cgtttaaagt ttagcattta agtgcttact ctaaaggcat agtgtaattt taggactcct
     2881 tattacggaa tctaaagtta ccctatgtct tttttgctat tcaaaattga tagcaaggag
     2941 aaagtgcaat gttgaatagt tgcgagtatg cggacgtttt agctaaaatt cttaaaaatg
     3001 gaattaaaca gtttaatagc aaaaatctag ttgcttttaa aaagaatagc aataagattg
     3061 gtgctattgc cggatttact tctaaaacaa acatgataaa gactaaaggt cttatatatc
     3121 gttctattga tcgtgtcttg gaagattcag atgtattaac acactggact cctaacgtgt
     3181 attcatggct tggtggcggt gaaaacaaaa caatttttgg tcacaaagaa gctaacttaa
     3241 ttcagattaa tacttttgta gcagatattg actatccagt aggagaaaag aaaacggatt
     3301 tgaatttact agttctttat ctattggaag aagggttatt gcctacattg attgtagata
     3361 cgccaaaagg ttatcattgc tattttctga ttcaaaacta taaccaagaa actgattcat
     3421 ttgataaggc aagctatatt tctaattcaa atgattttaa atctttgaga gttgctaaaa
     3481 gaatatcaga aaatatcaga aaatctatcc aaaatcgttt accacaagtc gatatgggct
     3541 gtaatcattt tggtattttt agatttccaa ctaaaaaaaa tattgtacat tatgaaccta
     3601 atttcgtaga tacgtttgaa gggtatttga aatggtcaaa agactttgaa gaaaaagaat
     3661 atgctttaaa gaggtctaac ttgtcattat tagctcctaa ttctactggc aagaaagggt
     3721 ctaaacgaca aattgatact aaatggtacg actttttaat tcatacggat attgctgaag
     3781 gagatagaaa taaaactgtt tttaccttag ccctggcatg taaatcaagt ggcttatcta
     3841 ttggcgagtg tatggatcaa ttggatcaac ttcaattcaa taatgatttg tcctattctg
     3901 aagttgagag aacaataaga agtgcttatc gtggcgatta caaaggtgct aaaagttcat
     3961 atgtcaatga aattatcgaa aattatgcta cacctaccga gtttgaaaaa tactcaataa
     4021 atgtaaatag acaagctgtt aaacgtaaag ggaatcgtgt cgatccgtct aattgggtga
     4081 aatttgctaa acctagagaa gaacgaaaat atagtcattt tgaagaaagt aaagctgatt
     4141 tattagctta cttagaaaga aaacaaagat cattgaaaaa aaatgagttg tttttaagtg
     4201 tctctatggg aactatatct gaagaaacac aaattcctgt atctacgtta aaggtgattt
     4261 taaaagagct tagaacggcg aatacagtga tattacaaac gtctcgtggt cggtatggat
     4321 cgactaaaat agcaacaagc aaatttgtgg aagctaaaat attaagtaca gttattcaga
     4381 ataaaaaaga taaacaagta tttgtcttag aattattagg aacagcaaat agccacgtag
     4441 aaacgatttt aagacgttat gaagacaaaa cagtaccgtt ccatgcgaac atactgaaag
     4501 aaagagaaaa gagcaaacat gcgccaatta gaggagctaa tacaggttag agttctattt
     4561 atttttttga tttttaaata gctaaattgc caattaacat atctagtgtt tctgctcact
     4621 cctattcctg ttttaacgta tactaatcat tagtagttag tactctcttt tacgtatgga
     4681 gtgcatagaa ctatttttac ttgtgtcttt tcccttaatc cacgtgtacg gaatacagct
     4741 tataactgcg tatgcagtta tgtttgaagg aggaagattt tctgtggtaa ttaagaaata
     4801 tgtttactca cacccgatca atgtatttat tatcggtaag ctaggtttat ctgttgaggt
     4861 gttttgtgag ttatatggat ttaaacaagg aactctatcg tcttggatta ctagagagcg
     4921 tgaggtagct gatttgccta tttctttttt gtatgctttg tctctagctt caggagggaa
     4981 tatgaatgag gtttatgatt gtttgtgtga gtatgaaaaa gagtataaag agtatttgaa
     5041 aatttcagcc ccaaaacgga ataaaaaata tattgaagat tagagaaaga agaaaagaat
     5101 aatttgcttt ttgactacaa gtagactgat agctactctg ttttttgata gtttgatatt
     5161 ggctgttttt ttgttagaat taatatatat caggtaaata aaaaaagggg gctattaatg
     5221 aatattgatg ggatttataa tgaatcagat tttaagaaag gcgatatagc ggtaatacgt
     5281 tcagagtatg attttccttc agaaatagga atccatacag tagagggaaa aactgtttgt
     5341 cgttattggg gtagaaaagg gaatttaata ttattattag atactgattc aggtgacaaa
     5401 ttaaagtttt gtttttggca taatactaat tattgctgtg aacctattcc aaaaagattg
     5461 attgatgtag ataaggaaag tgtaagatat ttagctgatg gaactaggat tagattaacg
     5521 tatcagaagt ctgaaaatgc ttcaattact cgtgtaagag atattgttgt aatctagtgg
     5581 gaggtgaagg attatggaat taatacctta tgcgtatcaa catttgtata aggctaaatc
     5641 aatgaaagat ggtaatgaag ttgttggagc gttgatttgt tgtccaccat tttcttatat
     5701 tgctaccatt gaatctatga agaagatgtg tgttgatgaa ttgaatgatg gtgaagttaa
     5761 aaatttaaaa ttaacacgtg tattagaacg ttcaattgaa gaatttaggt gaaggagaga
     5821 gtatttatgg caactgtaat tttagcagaa aaaccagatc aagcagagaa attcgctttt
     5881 gcgttagccg ataagaaaat tccaaaaagt ggaggaaagt ttgaatttca aagtgaggta
     5941 tttggagata cgattgtaac ttgggggata ggacatttag ttggattatc aatgccggaa
     6001 aaatatgaat ggctacctaa caaagaaaaa tgggatttag ctaatcttcc ttttttacca
     6061 aaaatggatg agttgaagta tgaagtttca aagggaaaga gtcagcaatt tgccgtagtt
     6121 aaggcgtgtt tagaaaatgc tgatcaaatt attatagcca ctgatccaga tcgtgaagga
     6181 gagaatattg cttataatat ttttaagttg tgtaagcaat ctatttttaa gaagcctatg
     6241 aagcggttgt ggattaattc tttggttaaa agtgaaataa taaagggatt taaaaacctt
     6301 agaaatgcag aggaaactat ttctttcttt gaagaagcaa atgcacgaca aattgcagat
     6361 tatttagtgg gaatgaatta tacagaattg tatacattaa aattgcaaca aaaaggctta
     6421 tctggggtgg tatcactagg tagggttcag acacctgtta atacattggt tgttgaaaat
     6481 gatttatcaa ttaaaaattt caagtctgaa aagtataaag tgattgaatg tcatactgtt
     6541 gacagagagc caaaagttat attcaaaaat agtcgagaat acttcaattt agatgaattt
     6601 gaagcagaca ctaaaaaata cggtttggat tccgccagta taggaattgt aaaatcagta
     6661 gaaaaaacat tgaagcaagt agaaccacaa aaattattta gtttaggggg gattcaagaa
     6721 tacgctaata aaaaatggaa atattctgct aaaaaaacag ataaaattat ccaaagtcta
     6781 tatgatcgtg gatatttatc ttatccaaga accgatagtg aattgataac tacaaatgaa
     6841 tttgagtatt taaaagcgaa tttagacgtg tataagagtg ttttagggat cagtattgat
     6901 acaccttgtt tagagcctaa aaagcggttt gtagataatg acaaagtatt agagcattat
     6961 gcactaatac caacaatgga tattcctgat atagcaaatc tgacattaga tgaaaaaaat
     7021 atttatgaga tcgttactag gcgtgcgtgt ctaatgtttg cagaacctta caagtacgaa
     7081 aatacaaaag ttacattaga tgtaaacggc ttagaattta ccacaagtgg taatgtacct
     7141 atatctttag gttggaagca agtagatact aatttagatg aatctgatga taaagaggaa
     7201 acattaccta aatttcatga acaagagaca ataaatatag atattagatt tattgataaa
     7261 ttaactaagg aacctaaaag gttgactgaa ggtaaattat taggtaaaac cggtattatg
     7321 gcgaaattag ggctaggaac gcccgctaca cgttctaata ttgtagacac tcttctaaat
     7381 agggaatata ttaagataga aaacacgaat gtttatccta ctccaaaggg atatttatta
     7441 tgggatttga caaagaataa agacctattg attggaaaac cagaaaatac agcgatatgg
     7501 gaagaatcac ttgggaaaat tgcgcaaggt agctatacac aggaagcttt tttaagaaat
     7561 atctataact atatcaataa gactgtttca gatttgaaaa aagtagaatt tacttcggat
     7621 tatttagaaa agactgtaaa tcaaaataaa tttgatatag gtagttatca agtggaagaa
     7681 aagaaaaaag tttattctat tttaaatatt actagtggtg aacagttcgt gatatttaaa
     7741 aatatatcag gaaaagcaat caataaaaaa gttcttcaag aactattact aaataatcgt
     7801 acagataaag tcctttccgg ctttaagtca aaagaaggaa aagcttttaa tgcaagatta
     7861 cttttcgatc caaatgtgat gaaagtggta atggagtttg aaaagaacag tccaaaaggc
     7921 gataaaaaga gcaaacacga tacagtaaat ggttatgaaa tagttgaaaa agcaaaagta
     7981 tttgaaataa aagaattagc aacaggtgaa agttttattt tctataaaaa taatagtggg
     8041 aaaactttaa gttcaaaaac agtcaaagaa ttgttagaaa atgggaaaac taaagagaaa
     8101 gtaacgggtt ttataagtaa agacaataaa aaatatagtg cttatcttgt ctttgat
//
LOCUS       DADVXB010000126         8101 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.129, whole genome shotgun sequence.
ACCESSION   DADVXB010000126 DADVXB010000000
VERSION     DADVXB010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.129"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            34..1188
                     /locus_tag="KB902_002261"
     CDS             34..1188
                     /locus_tag="KB902_002261"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBB6809045.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(1210..1962)
                     /locus_tag="KB902_002262"
     CDS             complement(1210..1962)
                     /locus_tag="KB902_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6809046.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2326..4992)
                     /locus_tag="KB902_002263"
     CDS             complement(2326..4992)
                     /locus_tag="KB902_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6809047.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5333..6784
                     /gene="cls"
                     /locus_tag="KB902_002264"
     CDS             5333..6784
                     /gene="cls"
                     /locus_tag="KB902_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6809048.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(7113..7928)
                     /gene="thiD"
                     /locus_tag="KB902_002265"
     CDS             complement(7113..7928)
                     /gene="thiD"
                     /locus_tag="KB902_002265"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBB6809049.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         2353 a         1686 c         1453 g         2609 t
ORIGIN      
        1 taagtttttt atcataagta aagaggtgtt gaaatgaaaa tagggattga tcgtctttcc
       61 ttttttattc ctaatttata tttagatatg acagagttgg cagaaagccg tggggatgat
      121 cctgcaaaat accatatagg gattggtcaa gaccaaatgg cagtcaatcg tgcaaatgaa
      181 gacatcatta cactaggagc aaatgctgcc agcaaaatcg taacagaaaa agaccgtgag
      241 ctaatcgaca tggtcatcgt cggaacagaa tccgggattg atcattcaaa agcgagtgcg
      301 gtaattatcc accatttact gaaaatccaa tcttttgctc gttcttttga agtaaaagag
      361 gcttgctacg gtggcaccgc agctttgcac atggcgaaag aatatgtcaa aaatcatcca
      421 gaacgaaaag tactagtcat agcaagtgat attgctcgtt acggcttggc aagcggtggt
      481 gaagtgacgc aaggtgtcgg tgctgttgcg atgatgatca ctcaaaaccc gcgtatttta
      541 tcgattgaag acgacagcgt atttctgaca gaagatatct atgatttctg gcgtccagat
      601 tatagcgaat ttcctgttgt tgatggtcct ttatctaatt ctacgtatat cgaatcattc
      661 caaaaagttt ggaatcgaca taaagaattg tcgggtcgag gactcgaaga ttatcaggcg
      721 attgctttcc atattccgta tactaagatg ggaaaaaagg cattgcaaag cgtattagac
      781 caaacagacg aagaaaatca ggaacgtctt atggctcgct atgaagaaag catccgttac
      841 agccgacgaa tcggtaatct ttacactggt tcattatacc tggggctaac ttctctactg
      901 gaaaattcga aatcactaca gccaggagat cgcatcggtc tattcagcta cggttctggt
      961 gcagtaagtg aattttttac aggttatctg gaagaaaact atcaagaata tctcttcgca
     1021 caatctcatc aagagatgct agattctcga acacggatca ctgttgacga atatgaaacg
     1081 attttcagtg agacgcttcc tgaacacgga gaatgtgcag aatatacttc agatgtacct
     1141 ttttcgatta caaagatcga aaatgatatt cgttactaca aaatataata aaatcataaa
     1201 aagaaccctt cacgagtcgt gaaaggttct ttttttatct gcggaccaaa ggagcagtct
     1261 ataggtcagc ttagtcgtac taaggatttc tcgtttttca ctgaatagtt tgcgaatgta
     1321 cctggtcaca acaggatctt ttgcgtacgc gtcatagtat agcttcatca attcttcagt
     1381 aattgattcc tgtgtaaaat aagtaaaatc ttttttcttc actttgaatc cttcatcaat
     1441 taagtatgtt tcaaattgat ccattacaac tggcgatgta ttaggatctt cttctatcat
     1501 tcctagttgc ttttcgatag gataaaaaac atcatcgatt gattccacta ctctgattat
     1561 cacgcaccat ttgcttgact ttttcatcaa tttttctaat tgaataagat gtaccaatgc
     1621 tggatttgct gctgtaaaaa ccatttcata tgtctcattt gattggataa attcttctaa
     1681 cgactgtttg ataaaggaaa catttggcaa ctcatttttt tctgcttctt tttttgcatt
     1741 ttctagcatt cctgaagaaa aatcgatcaa atcatagcga ttaatttctt ttgctaagga
     1801 aagaaatctg ccagatcctc cagcaacgtc tgctgctgtt tcagcaggca ggactttctc
     1861 cgttttcaga taatttttta catcttcagc aatagttact tgcgattctt gctggatttc
     1921 ataatattct tcagcaaatt catcccattc tttttcattc atttgatttc ctctaatttt
     1981 ttgttatatg ttttcacttt tcggaataaa tcattctcct cttttatcta ttctatctct
     2041 tttgatgaat aataaaatga ttggctttcc gtctatcata aataaaaaaa gggactgtga
     2101 ccaaagtcgt gtcaaagtcc ctctttccga ataaacagtg tccaatcaga tgaccctcag
     2161 tattagctca aaatgctgat tttacaactt cttccttaaa cggtgttctc ctgccaactc
     2221 ttcggtcaca agtcacaata ttcaacaaac atgagaagct gtttgttgaa attgcacctt
     2281 gtgactcaga attaaacggc aggctcacaa cctcgttgat tcgttttatt tatttccttg
     2341 tactcgtaca atgatcaatt tagtgatttc catcaaaaca attgtcacaa gtgcgattcc
     2401 catacatgta aagacttctg tcaatccaaa tgctgatggg atagagaaga cttctttcag
     2461 tcctgggatc attgttaagc agtaaagcgc gctacataca actacagcta gtaagacact
     2521 tctgttagag aagaaccctg cttggatagc tgtttgtgtg tttgaacgtg ctgggaatgt
     2581 ttgcaatgtc cgacaccaaa tcaatgttga aaatgacatg gctacaccga attcaggtga
     2641 atgctgcatg ccaagccatt gagcaaagat aacagcaatc ccaatcagca caccacgata
     2701 cgttacagaa atcaatgttt tgtccgtaaa gattcctgaa tttggatctc ttggcgggcg
     2761 gttcatcgta gcaggttcag ctttttctgt acctaatgca attgctggca gtgaatcatt
     2821 gactaaattg atgaacaaca gttgtaatgc tgtaaatgga ttggaccagt cagcaactaa
     2881 ggcaaagatg atcgcaatga tcgcacctaa atttcctgca aatagataag aaatagcttt
     2941 cttgatatta tcaaacacat tacgtcctac ttctactgcg ctgacaatag aagcaaagtt
     3001 atcatccgtc aataccatcg ctgctgcatc ttttgccaca tctgtacccg ttcccatagc
     3061 aattccgatg tctgcttgtt tcaatgctgg tgcgtcattt acaccatcac ctgtcatagc
     3121 tgagatatga cctttatttt gccaagcacg aacgatacga attttattct caggtgaaac
     3181 acgtgcataa acagtgactt tttctaaaac ttcgtttagt tgatcttctg tcaattcatc
     3241 tagttccgtc ccggtcaaag ccaggtttcc ttcttcaaaa atcccgattt gttttgcgat
     3301 agcaacagct gttgttttgt ggtcaccagt aatcatgatt gttttgattc ctgcacttct
     3361 tgcttctgtt accgcctgag tcacttcagc acgtggagga tcgatcatag caagcaaacc
     3421 aacaaggatc aaatcgtctt catcttcaaa tgataaatca aaattatcaa gtggacggta
     3481 agcaaaagct agtacacgta atgcgcgtgt tgaaaaagct tcattttgct cttggaattt
     3541 tttcatcaat tcatccgtca tcggaacgac ttcaccattt agcaatactt ttttactgcg
     3601 ttggaagacg atatctggtc cgcctttaac aaacaagtaa tttttgttat caattgtgtg
     3661 tccagtagac attaattttc gatctgagtc aaaaggaagt tctgcttgtc ttgggtagtt
     3721 gtttcggatt tcctgataag gctggtttaa tttttcacta aagtcgataa acgctacttc
     3781 cgtagggtcg cccaatttag taccgtcttc actgatcgat gcatcattcg ctaaaacact
     3841 gatttcgatc aagcgacgtt cgtcagctgt ccattttgaa gggtcatttg tgaaatcccc
     3901 agtatcgcca ttacctaaaa agtagtcaac aactgtcatt ttgttttgtg tcaatgtacc
     3961 agtcttatct gtacagatga tacttgtcga accaagtgtt tcaactgctg gaagcttccg
     4021 aataatggca tgacgttttg ccattttatt cgttcccaaa gataacacga ttgttacgat
     4081 agactgtaat gcttctggaa tagcagctac ggctacggct acggcaaaca tcactgcgct
     4141 gacgatatct gcagtcatat ctcctgtacc ttctccaaga taaatacgaa acagttggat
     4201 acctaaaatc aataaagaca atgccaaaat agccaaactt agttttttac tgaatttatc
     4261 cagacctcgt tgtaacggag tgacttgctc agttgttgat tccaaaaggc cagcaacttg
     4321 tccgatctcc gtattattcc cagttgaagt cactaagaat ttaccgcgtc cgtaagttac
     4381 gatcgttcca ctgaatacca tatttgtacg atctccgatt ggtaccgtac ttgtgatatc
     4441 cgttacttct ttttctgcag aagtcgactc tcctgtcagc ataccttcat ctacttttaa
     4501 tgatcccgca tctagtaaac gtccatcagc aggtacataa tcgcctgcgt ctaacaacac
     4561 gatatctcct accacaagtt cgtttgccgg aatcgttttt tccttaccat cacgaatcac
     4621 tcgagcatcg ggcgctgaaa ggtttttcaa cgcttctaaa gaaccttctg ctttttttgt
     4681 ttggacaaca ctgattatag aattcaacat caatactgca aaaataacta agaattcgat
     4741 gtagtcaccc atgaccatct gaatcagtgc gacaatcagc aatacgataa ccattgcatc
     4801 tttgaaagtt tctaagaaca atttccaagt tggcttcttc ggcttttctt ttagctggtt
     4861 caagccatct ctttctaatt tttccttcgc ttgcgtggtg ctcaatccat cggttgagct
     4921 ctgcgtttgc tgcatcaacg agtcgatcgt ttctttatag accgcttgtt gtgcttgttc
     4981 cttgttttcc aaatttcatc ccccattttt tgatcttggc cctagtcctg tctgaaaaaa
     5041 aagagaccta agacaaatac gcatttgtct taggtctcac catttcatac aataccagaa
     5101 aaccatttgg ttaacttact gttgatatta tcgcaacaaa cgttgccggt tactccccta
     5161 aggagatatt caactgtact aatatcctac cttattaacc tacaaaaagc aactacttta
     5221 gcccgattta cctacatttt catgaaagga gtgaaaagta tattcacctt ggtaggcttc
     5281 tttcttctat catgctatac taatgttatt gtatgtaagg aggaacattt ttgtggtatc
     5341 tagtattata accgcccttt atctattaaa tgcacttatt gctttggtgg ctattttgat
     5401 caaaccccga gatgtagcag ccatttgggc atggctctta gtattgtttg cccttcctgg
     5461 ggtgggcttt gtattatatt tatttttcgg acgtggatta acggataaga aaaaattcta
     5521 tctccgacaa agtgacttga aagaattaga aaactttcag tcttttagag gagataccat
     5581 tgaacattac gatcctgaca tgggcgataa agacaaacag caatttgttg acttcttctc
     5641 ttcattaaat cgtatgccgc tgacaagaat gaattctgtc actcttctca cagacggaca
     5701 agagaaattg gattcactgc ttcaagatct aaaaaaagcc aaacattcga tccatatcga
     5761 atattacgca tttgtgacag ataatatcgg ccagcaagtc ttacatgttt tagaagaaaa
     5821 agccgcagaa ggcgtggaag ttcgaatatt atatgatgca tttggctctc atggcacaaa
     5881 agcaaaagat ttcaatcgtc taatcaaaaa tggtggacat gtccatacat ttgttacctc
     5941 acaaagggca ttacttcgtt tccgattgaa ttaccatgat caccgaaaaa tcgttgtgat
     6001 cgatggaaag attagttata ccggtggttt caatattgcc aatcaatatg taaatacaac
     6061 aaaaaaattc ggctattggc gcgatacgca tatacggatt ttcggtgccg cttcttcttt
     6121 gctccagctt cgcttcttaa cagactggaa cgtctcggta cctgaagaaa aaaaggtcgg
     6181 ctatcatttg aattatttct ttaaaaaagc agatcgagat gaatctaagc ttgctgatac
     6241 atccatccag cttgtttcaa gcggaccgaa taacgaaagg gaacaaatca agctttcatt
     6301 tatcaaattg attacttctg ctaaaaaacg tgtttggata cagacacctt accttgttcc
     6361 tgatgaaagt gtcattgctg ctttaaaaat cgcaactgcc tctggtgtag atgtgaaaat
     6421 catgattccc aacaaaccgg atcatccttt tatttatcga gcaacacaat attatgctcg
     6481 gcagctgatc aaggaaaatg tacaaatcct tgtctatgag aacggcttcc tccatgcaaa
     6541 aacattgata atggatgatg aaatctgcat ggtaggttca gcaaatcaag atattcgtag
     6601 ctaccgattg aattttgaaa caagtgctgt catttacgat cctgagtttt tagaagaact
     6661 tgctactcag ttcaaagaag atgagacaca ttgttcatcc atgacaactg aaacagtcaa
     6721 ggaaatgtct aactggctat tattcaagca acaaatttct cgattatttt ctccaatcct
     6781 ataatttttt tattcaagta gagaaaaata tactaagatt aaagggactg tgacaaaaat
     6841 cttgtcacag tcccttcttc cgaacaaacg gtgttctcct gccaactcct cggtcacaag
     6901 tcacaataat caacaaacat gagaagctgt tttttgaact tgttccttgt gactcggagc
     6961 tggacggcag gctcacgacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa
     7021 taagtccaac caagttaaaa acataagaag ctgtttttac ttggctgttc ttattacttg
     7081 atgcagggca actttttcac aacttctttc ttttactcta attcaccagc tgcccaatga
     7141 ttgatggggc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     7201 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     7261 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     7321 aaccaaaatg attttcctga ttcgaacaat acgtagtcat tgactgtttc ttgctgcgca
     7381 tttttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     7441 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     7501 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     7561 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     7621 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     7681 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     7741 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     7801 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     7861 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     7921 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataata ctgttactgt
     7981 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     8041 tcaaatttat ttgaaaaaac atttgcaata aatcagaaaa tagtggtcgt ttatttgtat
     8101 t
//
LOCUS       DADVXB010000127         8020 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.130, whole genome shotgun sequence.
ACCESSION   DADVXB010000127 DADVXB010000000
VERSION     DADVXB010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.130"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            4..1458
                     /locus_tag="KB902_002266"
     CDS             4..1458
                     /locus_tag="KB902_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HBB6809050.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
     gene            1534..2694
                     /locus_tag="KB902_002267"
     CDS             1534..2694
                     /locus_tag="KB902_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBB6809051.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            2807..3814
                     /locus_tag="KB902_002268"
     CDS             2807..3814
                     /locus_tag="KB902_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6809052.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            3838..4863
                     /gene="iolG"
                     /locus_tag="KB902_002269"
     CDS             3838..4863
                     /gene="iolG"
                     /locus_tag="KB902_002269"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HBB6809053.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            4880..5770
                     /gene="iolE"
                     /locus_tag="KB902_002270"
     CDS             4880..5770
                     /gene="iolE"
                     /locus_tag="KB902_002270"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HBB6809054.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            5793..7388
                     /locus_tag="KB902_002271"
     CDS             5793..7388
                     /locus_tag="KB902_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HBB6809055.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            7404..7718
                     /locus_tag="KB902_002272"
     CDS             7404..7718
                     /locus_tag="KB902_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6809056.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
BASE COUNT         2377 a         1521 c         1934 g         2188 t
ORIGIN      
        1 taaatgacaa gatttttaag aaattatatt gatggtcgtt gggtcgctag tcgctcaaca
       61 gagtttgaag aagtaatgaa tccggctaca gaagaagcgc tggcgaatgt accgttgtct
      121 agcaaagcag agacagccga agcagttaaa gctgccgatg ctgcgtttca aacttggaaa
      181 aaagttcctg ttcctgttcg cggacgttat ctgttcaagc tgcatcagct tttaacagat
      241 cataaaagtg aattggcgcg tttgatcacg ctggaaaatg ggaaatcatt gtccgagtca
      301 ctgggagaag ttcaacgagg aatcgaaaat gtggagcacg cagcgggaat caccaattta
      361 atgatgggag attctttatc aacagcggcg actgatattg agatcacgaa ttatcgttac
      421 ccaatcggag taatcggagg gatcacaccg tttaattttc caatgatggt gcccttctgg
      481 atcttcccga tggctctggc ggcaggaaat acggtggtgc tgaagccttc agaaaaaaca
      541 ccattgttga tggagaaaat tgttgagctg gttgaaaaag caggctttcc tagcggtgtt
      601 tttaatgttg tctatggtgc ccacgatgtt gtcaacacat tgctgcaaga tccactggta
      661 aaaggcatca gctttgtagg atcaaaaaat gtcggtgaat acgtttaccg tgaaggaaca
      721 aaaaatctaa aacgggtaca agcgttgact ggagcgaaaa atcatgttgt tgtgctgaaa
      781 gatgccaata ttgatcgggc agtcaaggac cttattggcg gagcttttgg ttctgctggt
      841 gaacgctgca tggcagcctc cgtcattgtt ttggaagagg aaatcgcgga tcagtttgtt
      901 gaaaaattta aggctgcggc aaaagcgatc aagatcggca atggcttgga cgaaggggtc
      961 tttttaggac cagtgattcg aaaagatgca cagcagcgga cctttgacta tatccaaaaa
     1021 ggggtcgatg aaggagcgaa actggtacta gatggtcgcg aaaacattcc agaaaaaggc
     1081 tattttgttg gaccaacgat ttttgataat gtcacgatgg atatgaagat ctggcaggat
     1141 gagatttttg ccccggtcgc atcaatcgtg cgggtaaaag atttgatggc agccgttgag
     1201 ctgacgaatg aatctgaatt tgcgaatggt tcgtgtctgt ataccaacaa cgcatcagcg
     1261 attcgctact tcagagaaaa tgttgatgct gggatgctgg gggtcaatct tggggtgcct
     1321 gcaccgatgg cttggtttgc cttttcaggc tggaagcact ctttctttgg tgatttgcat
     1381 gccaatggca aagacagtgt tgagttttat acccatcgga aagttgttac agcacgttat
     1441 gcgcaaagtg agatttaaag atttgcttcg aagctctgtt aaagagcttc gaggattctg
     1501 ttataggcta taagccagag agaggttttt tctgtgaata ttcaactgaa aatgcctgcc
     1561 aatttaagaa ttggcggcgg aacaatccaa tttcttatgg aagaatcaga acaactaggc
     1621 aacaagccgt taatcattag tgatacggtt atggaacaga ccgggcatct tcaaaagatc
     1681 aaggagctgt tgggaaaaac agatgatcaa ttagcggagt atacagacat tcaagccgaa
     1741 ccgacgcaag aaaatgttta tgatgcgctg aagctttttc agaagcatca atgtgatcat
     1801 atcattgctt ttggtggcgg cagctgtctg gatacagcca aggtggtagc cgttttggct
     1861 gctaatcaat taagtctcga agcgattcat gcaagaaatt ttgatcagct gcaagcgggc
     1921 attccgctga ttgcagtgtc aacaactgct ggaactggtt cggaagtaac cgatgtggca
     1981 gttattacca atacaaaaac agcagtcaaa atgatgatga aggatctcgt tttcatgcca
     2041 cagatctcaa tcgttgactc tgattttacg aaaactgtac caccaaaagt aaccgcggca
     2101 acgggagtcg atgcgctatg tcacgctttg gaatcttatg tttcagtcaa agccaatgaa
     2161 gtaacgcaac tattttcact ggaagcgatg aagaaaattt tgaacacgct ttctcaggca
     2221 tatgaaaata gcgacgacac tgaagccaga gaacaaatga gcttagcttc aacggaggcg
     2281 gggattgcct tttcgaatgc gtcagtcaca ttgattcatg gaatgagtcg accggtgggg
     2341 gcactttttc acattcctca tgggatatca aatgcgatgt tattgccggt cttttttgaa
     2401 ttctcaaagg atgctattca gactgagtta gcgacgatcg ccagatttat ttatccggca
     2461 gccgaagatt tatcgctgga agaggctgcg gattatctga ttaaaaaaat ccaagagctc
     2521 tgtgagcagc tgtcgatccc aacgattcga gattatggta ttgatcagca agcgtttatg
     2581 gcagccttag acaaaatggc cgcggatgcg ttgaccagcg gaagtccgca aaataataaa
     2641 aaggtgccta gtcatagtca aattaaggaa ttatacgtac aagcttatgg gtagtaaaag
     2701 gcggagcaaa gagagggctc taccttttaa gaataaaagc tacacaggaa taattttgta
     2761 agcgcatact atgtgtgctt aaacaacaga acagggggat aagtaattga gagtaaaagt
     2821 aggcgttatc ggaacaggtg caatcggcat cgagcatatc gacaggatca atcagaaaac
     2881 acaaggggct tatgtgacag cagtctcaga tatcaatgta aaagctgcta aagaggttgc
     2941 caaacgtgtc gatgctaaat tctttgaaac cggagaagca ttgatcgctt ctgaagatgt
     3001 ggatgtcgtt gttgtgactt cttgggaccc gacccatgag cagtatgtgt tagaagcaat
     3061 caagcatggg aaatatgttt tctgcgaaaa gccattagcg atggatgcag caggctgccg
     3121 ccggatcgtt gatgcggaag ttgcttatgg gaagaaattg gttcaggttg gcttcatgcg
     3181 ccgctatgac cgcggctaca ttgaactgaa agaagcaatc gaatcgaagc aatacggaga
     3241 agcattaatg atgcattgtg cccatagaaa tcctagcgca gatgaaaact acacaacacc
     3301 gatggcgatc agcaacaccg cgattcatga gattgatgtg cttcgctggt tgctaaatga
     3361 agattatgaa tctgttcaaa tgatcttgcc gaaaaaaacc agcaactccc atgccgattt
     3421 gcatgatccg cagctgctga tctttcaaac aaaatccggt gtaacgattg atttggaaat
     3481 ctttgtgaat tgccgctttg gctacgatat taaatgtgat gtggttttcg aaacggcaga
     3541 agtaggaatg acggacccag cctatacacg aattaaatcg gaagaaaaaa attacacacc
     3601 tgtttcacca gattggcaga cccgcttttt ggatgcctat gattatgaat tcaagctgtg
     3661 gatcgattcg atcaaaaatg atgcggttgt cggtcctacc gcttgggatg ggtatgtagc
     3721 agcgatcacc atgatggctt gtcatgagtc tcgtgaaaca aaaacaaaag taatgattca
     3781 aatggatgaa cgaccagcac tatacaatga gtaattctca gaaaacggag gtatttcatg
     3841 aacaacatta gagtaggcat cgtcggttta ggaagattag gaaaagtaca tgcacaaaat
     3901 ttagcaacag gtgtcagttg ttgtgagctt acggctgcgt gcagtttagt tgaaacagaa
     3961 ttagcattcg cacagaagaa attaggcgtc aagcatactt tttccagcta tgaagaaatg
     4021 gtcaaaagtt ccgtgatcga tgcagtcttt attgtttcac catcaggctt tcactgtgac
     4081 caagtccgct tggcgatgga aaatggcaag catgtcttta ctgaaaaacc attaggcctt
     4141 gaagttgaag atattaaaaa gacccaaaaa gtcatcgaag agcatcctga acaggtcttc
     4201 atgttaggct tcatgcgccg ctatgatgag tcgtatcagt atgcgaagaa aatggtagaa
     4261 gatggcgaaa tcggcgaaat cacactgatt cgttgttatg ggatcgatcc gagcgaaggc
     4321 ttggaaagct ttgtcaaatt tgccatgaat aacgacagcg gcggcttgtt cttagatatg
     4381 gcgatccatg atattgattt ggttcgctgg tttaccggcc aagaagtcga tcaagtgtgg
     4441 gcgattggga aaaatgcggc gtatccagaa ttggatcagg ctggtgagct tgaaactgga
     4501 gccgcaatga tgagcctgag cgataaaaca atagctttac tagttgccgg cagaaacgca
     4561 gcccatggct atcatgtcga aacagagatc atgggaacca aaggaatgct gcgggtagcg
     4621 caagcgcctg agaaaaatct tgtgacgatc atgaacgatc aagggatcat ccgtccatgt
     4681 tcacaaaact tcccagaacg attcagagaa gccttcattc gtgaagccca agaatttgtc
     4741 tcatgtattc aagaaaaacg tcaaccagcg gttaatgcag aagatggatt gcaatcaact
     4801 aagatcgcgt tggcttgtca agaatcattc gatacgaaga gtttagtaca actaaaaaaa
     4861 taagcaggag tgtgagaata tgaccaaaca aattcaatta gccatcgcac caatcgcgtg
     4921 gaccaatgat gatatgcccg agcttggtag tgaaaatacc tttgaacaat gtatcagtga
     4981 aatggccctt gctgggttca ccggaacaga gattggcaac aaatatccaa aagatccaga
     5041 ggtgttggaa caatatttga atattcgcgg cttaaaggtt gccagtgcat ggttcagtgc
     5101 gtttctgaca actaaacctt ttgaagaaac tgccgaagcc ttcaaagcac atcgggattt
     5161 cttacatgcg atgggcgcta aagtcatcgt agtagctgag cagggtcata gtatccaagg
     5221 gattatgaca gcgccagtct ttgatgataa accagttttc actgatgaag agtggaaaaa
     5281 actggcggaa ggattagaaa aattagggga tttggcccac gaaaaggata tggagatcgt
     5341 ttaccatcat cacatgggta ccggcgttca aacgacggaa gaaatcgatc gtttaatgga
     5401 aatgactgat ccagacaaag ttaaattatt gttcgatacg ggacatttgg tcttttctgg
     5461 tgaaaatcca atcgcggttt acaaccgtca tcaagatcgt atcaaacaca tccatttcaa
     5521 agatattcgt caagaaacgg ctgaagaagt agaaaaggaa aaagacagct tcttaaacgg
     5581 cgtgaagaaa ggcgtcttca cggttcctgg tgatgggatg attgatttca ctccaatctg
     5641 gacagcaatc catgccagcg actatgaagg ctggatcgta gttgaagcag aacaggaccc
     5701 ggctaaagcc aatccatttg aatatgcagt caaagccaga agctacattc gagaggtcac
     5761 cggtctttaa tctattgaaa aggagctaga cgatgaatct tttttctata atcagtttcc
     5821 tagtgattgt catctgtgta tggttatttg cctattctag atccagaagt gtcgatactt
     5881 ctggatcaga agggttcttc atgggagggc ggagcttaac tgctttgcca atcgccggca
     5941 cgatcatcat gacgaacctg tccaccgaac aaatagtcgg acaaaatggt caaagttatc
     6001 atgcagggat ggaagtaatg gcctgggaag taactgctac gattgcgatc gtagctttgg
     6061 ctgtgatatt cttgccaaaa tattttaaat acggcatcaa tacaatctca gatttcatcg
     6121 agattcgtta tgatacggtt accaaacgaa ttatttcgat cttatttatt gtgacctata
     6181 tgacttcttt cttacccgtg gttctttatt ctggatcgct ggtgttcaat aagatcttcc
     6241 atattgatga gctgctgggc gtccagccga tcgtcgcgat cataattgta gcgatggcaa
     6301 ttggtattgt cggcatcctc tatctgctga tcggcggctt gtcgttaagt gccaatagtg
     6361 actccattta tggagtcggt ctgctggctt gtggtctgct ggtcccaatt ttaggcttaa
     6421 tgaagcttgg tgacggcagc tttgttggcg ggatcgaaca cgttgtggta aacacgccat
     6481 ggctgcttaa ctctgtggga tcgatcgact cggctgttgt tccatggccg acactattta
     6541 cagggatgct gtttaacaat ctgtatttct ggtgtaccaa tcaaatgatc gtccaaaaag
     6601 cattgtccgg caagaattta gctgaggcac aaaagggcgc tttcctagtc ggcgtcttca
     6661 aaatcttagg tgcgttattc cttgtctttc cagggatcgt cgctcgcaat atttttggcg
     6721 atagtttaat gtcaaatcca gataacgcgt atcctttttt agtcagtgaa gtattgccta
     6781 aaatgatctt tggtattttc gccgctgtta tctttggcgc gatcttatca tcatttgcgg
     6841 gagctttgaa cgcgacatcg accttgtttt cactggattt ttataaaccg cttatcaata
     6901 agaaagcaaa tgataagcaa atcgctcgtg ctggtaaaac agtaacggtc gttgtgggga
     6961 ttatctccat tatcgtagcg ccattcattt cttttgcacc ggctggattg tatcagttcg
     7021 ttcaagaatt caatggacta tacaacatgc cgctgctcgt gatcattctc tttgcctttt
     7081 attcaaaaaa agcaactgct tttggggcaa aaacgacgat tgccgtgcat atcgtcttgt
     7141 atgcactatc aaaaatgctt ttccaaaata tccatttcct ttatgttttg acggcattat
     7201 tcgttctgga cattatcatt ttgatggtgg tttccaaatt gaaacctgat ggagaatttg
     7261 tgttgaactc attcgataca aaggtcgata tcgagccttg gaaatacacc aaggtgactg
     7321 ctatagcatt ggtagtcatt gttattttaa cttatgtggc attttcacca attggctttg
     7381 caggctaaaa acaggagggt attatgcata aggatctatt gattatttgc gagaccggaa
     7441 tcagtgcgtc gctgctcgta tcaaaaatgc ttgaaacgat cagagccaaa aatctatcgt
     7501 atgagataga ttatgcaacg atccgaaacg ttgaagaaaa actgaattat aaagactatg
     7561 acgttttact tttaacgccg caggtcgcac gttctgagga aaaagtaaaa gaaatcatca
     7621 aaaaggaaaa atgtaccgct cagatcgttt atatcaaaca agaagatttt cgttatatga
     7681 atattgaaaa catcattgca agcatcgaag aagattaacg agaatctttg attattgagt
     7741 gtcgaggagg tggtatatga aaagatggca tgttcgcccc gatcacccca atatgaaggg
     7801 cggacttatt agaaataccc aatcttgtat ttattcaata gggtaagcgg acctcaatag
     7861 ccagctcatc cccaaaaagt cgaatggaga cacttaaatg agtgtaccta ttcgactttt
     7921 tgagactcta agtcaaatcg tgttgttctc attaaatcac tgaaaggaaa tgcttcggcg
     7981 tttccttttt tctttttgtt tttcttcgtg ttttgaaaat
//
LOCUS       DADVXB010000128         7901 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.132, whole genome shotgun sequence.
ACCESSION   DADVXB010000128 DADVXB010000000
VERSION     DADVXB010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.132"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            151..1917
                     /locus_tag="KB902_002273"
     CDS             151..1917
                     /locus_tag="KB902_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBB6809057.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2019..3278
                     /locus_tag="KB902_002274"
     CDS             2019..3278
                     /locus_tag="KB902_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6809058.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3425..4726
                     /locus_tag="KB902_002275"
     CDS             3425..4726
                     /locus_tag="KB902_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6809059.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4729..5580
                     /locus_tag="KB902_002276"
     CDS             4729..5580
                     /locus_tag="KB902_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6809060.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5593..6408
                     /locus_tag="KB902_002277"
     CDS             5593..6408
                     /locus_tag="KB902_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBB6809061.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6559..7725
                     /locus_tag="KB902_002278"
     CDS             6559..7725
                     /locus_tag="KB902_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6809062.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT         2563 a         1364 c         1580 g         2394 t
ORIGIN      
        1 taaaagtttt aagtctatct atttggcaag tttaaaaaat aaaaattcgg tatcaaaaaa
       61 ctgttaccga taacattttt gaaagcgttg tcttttgttt ctctatcact tatagtgatg
      121 acgtcatatt aaaacacaag gaggaaatca atggatacag ctgcaattta tcatcgaccg
      181 gaaagtgaat atgcatttct atatacgaat acaagatttc gtattcggct tcgtactagg
      241 aaaaatgata tcaaaaaagt atatgtgctt tgtggagatc catataccat aacaactgaa
      301 aaatggtatc aaaaacaacg accaatgaaa aaatgtctaa gtaccaatgt tcatgattat
      361 tgggaaattg aagtgacgag cgaaacaagg cgcttacagt atgcgttcca tgttgttggg
      421 gaagataaca cggactgttt ttacggtgat caaggaattt ttccttatcg agaaaatgtg
      481 attactgaac caaattttta ttttcgaata ccttattttc atcaaatcga tcgattcact
      541 attccagaat gggtaaaaga aacagtatgg tatcaaattt ttcccgaaag atttgcaaac
      601 ggggacaaag caaatgaccc cgaacacact ttaccttggg gaagtaaaga tccagaccga
      661 gaagacttct tcgggggaga tttgcaaggt gtgagggatc atttggatta cttgacggac
      721 cttggcgtca atggcatcta tttttgtccc atatttaaag ccacatccaa tcataaatac
      781 gatacgattg attattatga ggtggatccc gcttttggcg ataaaaaact tttaaaaaac
      841 ttgattgatg aagcacataa aagagggata cgtatcatgt tcgatgctgt attcaatcat
      901 atgggtgtcc attcaccaca gtggcaagac gttctcaaaa acggagaaaa atcgatctat
      961 aaagactggt tccacatccg ttttttccca gtagattctt atcagatgac tgacttacca
     1021 gaaactgctg aaaatatccc atatgatact tttgctttta ctccattcat gccgaaacta
     1081 aatacagcaa atccagaagt gcaaaaatat ttgctggata tcgcaactta ttggataaaa
     1141 gaattcgata ttgatggatg gcgtcttgat gttgctaatg aagtcgatca tcatttttgg
     1201 aaaaaattca gagaagcagt tacagaaatc aaaccagaca tctatatcct tggagagatt
     1261 tggcattcct ctcaagcttg gctgcaaggg gatgaattcc atgcagtgat gaattatgca
     1321 ttcacagatt cgattaaaga ttattttgca aaaaagaaaa tcacagcttc acaaatggtc
     1381 agtggaatga atcatcagca aatgctttac agagatcagg tgaacgaagg aacattcaac
     1441 ttattagatt ctcatgatac tgccaggatc ttgacccttt gccaaggtaa caaagaattg
     1501 atgaagtctg tgatggcctt tatgtttctt caaaaagggt ctccttgtat ctattacggg
     1561 acagaaatag ggatgactgg tgaagatgac ccggattgcc gcaaatgtat gatatgggag
     1621 aaggaggaac aagatctaga gctattcggt tttataaaag aacttgtttc tctaaggaaa
     1681 cagttgtcta agattatttc tgaaggttct actcagtggc taatagtata tgatcgtgaa
     1741 gataagctct atttcacacg ggaactagag ggacagatca tctatgttta ctttaatcag
     1801 tcaaaagaac cttgggtagt agaacaggaa aatgaggtga ttcttagtca aaattgtcag
     1861 ttgttagaag acgggaaagc agagatacga caatacggat ttttgatcat gtgttgaaaa
     1921 ctgttaccgg taacaacaag aaagcgtttg caaatgaaga tttgtgccca ttataataag
     1981 ggtgtaacag cacgttgaat acacaggagg aaatgaagat gaaaaaaaga agtgtgaaac
     2041 agttgggttt agggttaatc tctttaggaa tcttaggcgg attagcggct tgtggcaatg
     2101 gtaactcttc agcagaaggg gaagccgatg aaggaaaaac gttaacagtt tccgttgatt
     2161 ctggatataa agattatata aacgaaataa aaaacacttt cgaaaaagaa aacgatgtga
     2221 aaatcaagct agtagaaaag gacatgttcg atcagttgga atcattagcg ttagatgggc
     2281 ctgctggaaa gggacctgac gttatgatgg cagcatatga ccggatcggt gcgttaggac
     2341 agcaaggaca tctggcggaa gtaaaactgg gaaatgaagc agcttacgat gaaacagaca
     2401 aagcccaagt gacttatgat ggaaaaatct acggagaacc tgcagtaatc gagacccttg
     2461 ttttgtacta taacaaagat ttagtcgata cagcaccatc aacgtttaaa gatttggaga
     2521 atctatccaa agacagtcgt tttgcttttg agtcagaagc aggaaaaaat acaggatttt
     2581 tagctaaatg gactgacttt tattattcct atggtttaat tgcaggttac ggtggctatg
     2641 tatttggtga tgatggcaca aatccttcag atatcggttt gaataatgca ggtgctgtag
     2701 aaggaatctc ttatgcaaca gattggttca aaaatgtttg gccaaaggga atgcaagaca
     2761 taaaaagtgc aggagacttc gccagccagc aattcatgtc caataaaact gcagcaatca
     2821 ttgacggtcc atggcaagcg caaacataca aagaaaacaa tatcaattat ggtgtagcca
     2881 aaattcctac tctaaataat ggacagcctt atcaaccgtt tggcggagga aaaggatggg
     2941 tagtcagcaa ttatgctaaa aacaaagacc tctctcaaaa atggcttgat tatgtaacga
     3001 atcaggaaaa tcaagaaaaa ttctttgaaa tggtaaatga aatccctgca aaccaacaag
     3061 ctagggaaac agcaaaggct aaaaacgatg aattaacaac agctgtgatt gaacaatatg
     3121 aaacagctca agcgatgcca aacatcccag aaatgggcga agtttggaca ggtgcagaaa
     3181 acttgatgtt cgatgcagca tcaggttcaa aaacaccaaa agaatccgca gatgaagcag
     3241 taaaaacaat cagtgaagcc atagaacaaa aatactgatt aaaatgataa ccgtccattt
     3301 ttataaaaaa tggaacaggt gcttcagata aaagtggcaa gagcgagatg gaaaattatc
     3361 ttgctcttgt tgccattatc ttaaaagcag tttgcggttt agcaagttta gagggggcat
     3421 tcagatgcag caagataaaa caagcaatat caacgaaaaa aaaatcacgc tttgttcact
     3481 tattccaggg atggggcagt ttgtaaatgg ccaagctttt aaaggtatcg tttttttcgc
     3541 catattcgtc ctattcattg gtcagatgct tctgggcgga tttcatgcat tggtaggatt
     3601 ggttactttg ggaagtatac caatggaaga tcattcatta tttattttga ttgaaggcac
     3661 tttgcaattc atcattacaa tcattttctt gattttttac ggtttgaatc ttttagacgc
     3721 ttatcgagta gcgaagatgc gtcaagaggg caaaaaaatc aatcggacga tgaaggaagt
     3781 catacataat ataggtgatg aaggttttcc ttatctattg acacttcccg cttatcttct
     3841 catgattttt acgatcattt tcccagtcct agttacattg ttcactgcat ttactaatta
     3901 tgacttcaat catattccac cagccagttt aattgattgg gtaggggcta aaaacttttt
     3961 tagtatcttc tttttaagct catatcgtaa tacttttttt gcagtctttt cgtggaccgt
     4021 gatttggact ttatgtgcaa caactttgca aatcaccctt ggtattctca cagcggttgt
     4081 tgctcaccag aaatttatta aattcaaacg tattttcggt atcattttct tattaccatg
     4141 ggcggtccca gcttttatta ctatcatgag tttttcgaat atattcaacg atagcgtagg
     4201 tgccatcaat actcaagtga ttcctttcat aaaccagctt ccttttgtag atatcagtgc
     4261 aatctcttgg aaaacggacc cgaactggac gaaagtagca attatcttag tgcagggctg
     4321 gttaggattt ccctatatct atgtgatggt tacaggaatc ttacaatcga tttcagaaga
     4381 cttatatgaa gcagcaaaaa tcgacggagc aaatgcatgg cagcgctttt caaacatcac
     4441 gcttcctgct gtcttcctag tggcagcgcc aacatttatt acacagtata cggggaattt
     4501 caataatttc tccatgatct atctgtttaa caatggtggt cccggaagcg taggcggagg
     4561 agctggttct actgatattc ttatttcctg gatctataaa cttacgactg gaacttctcc
     4621 gcagtattct atggcttcag caatcacgtt gattatctcc gtcatcgtta tctgtgtgtc
     4681 attgctggta tttaaaaaga caaatgcgtt caatatgggg gattaacaat gaaaaaattt
     4741 cattcgagtg ctcgattcca aaaacgactt tctcactttt ttacttactt ttttctttta
     4801 atactgtcag tcattatcat ctatccgctt ttgatcacag caagtactgc cttcaagtca
     4861 ggaaatattg cagcttttag tttagatctt tcaagtgact ggactttagg aaactttact
     4921 cggctattca gtgaaacact ttacgggact tggtataaaa atacattgat catttctgtc
     4981 ctaacaatga tcgtacaagt gactgtagta actttggcgg gctatactta tagtcgctat
     5041 cgttttatcg gccgcaaatc aagtttgatg ttctttttag tgattcagat ggtaccgact
     5101 atggcagcat tgactgcctt ttatgtcatg gctttcttat tagaagcgct cgataagtac
     5161 tggttcttga caatgatcta tataggcggt ggaattccaa tgaatacttg gctgatgaaa
     5221 ggatactttg acactgtacc aatagattta gatgaatctg ctaaacttga tggggcaggg
     5281 catttcagga tttttttcca gattgtatta ccgcttgtca aaccgatgct cgccgttcaa
     5341 gcattatggg cttttatggg accttttggg gatttcatgt tagctaagtt cctgcttcga
     5401 acacctgaaa atcagactgt tgctgtcggc ttacaaacat ttatttctga tgtgacaaac
     5461 caaagagtct ctctttttgc tgctggggca attttgattg cactaccgat ttgtctatta
     5521 ttcttctttt tacaaaagaa ctttgttacc ggcctgacat ctggcggaac aaaaggatag
     5581 gagcagagta tcatgcaaac atttccgtta aactattttt ccgcattacg tacgccaact
     5641 caagtgtttg cgggacgcaa actattatca tggcctaaat ttttcttgat atttgtattt
     5701 ttagtttcct tgatggtcat gcctgtgact cttttttatg ccaatcagat ccaagcgatt
     5761 ccattagaac aatttctatc cgttcattcg ctgatcgatg aacaaggaac ccaaaaattt
     5821 tctgaacttg aattatctga aactgggtta caagcatcgc aacaaacgat agctgtgacc
     5881 cctgaaattt tggtaggtgt gtctttatct gagaaacaac aatccgatca tggaactttt
     5941 attgattttg agaaggaaca atgggtgatc caacaaaagg ataaatctgg tatacgccgc
     6001 tatacgatga attatagccc atctttccaa ccagattctg tacgtacgcc cgaagatttc
     6061 caacgatttt tagaaagaga attttatgcc agtaatcgtc caacaatcat tttatcttat
     6121 agtttaagtc ttggtcttgt cctatttgtc atgacgagtc tcattttatt cggggcttcc
     6181 tttttcttgt ggatgacaag aaaaagccaa ctttcatcca ttcatacatt caaagagagt
     6241 gcaaatttga tgctgaatgt tatgggaata ggttccatgg cagcagcagt tgtagggttt
     6301 atccactttg actttatctt gatgctaagt gtccaaacaa cgataactgt cttgctgctt
     6361 ttatgggttt ttgtcaaaac aagattcaaa gataagcgtg tcgaatgaca agtttaagcg
     6421 atttatgcga caatgaatgt gaaaaaaatg aaaaataaag tagtttttga aaaatttctg
     6481 aaaaaattaa acttcttagt tgattctttt cttttttagt attaacgtaa tagggtagtt
     6541 tttttaagga ggaaaatcat gttagagaaa actttataca atcaattatt ttcacgttct
     6601 ttctcgctcc ctgtcgaagt aaattattgg gacggtacaa cgaaacaata cggagatacg
     6661 gacactcctc cccaaatcaa aatcaatatc catgaagaaa tcccaatgaa agagattaca
     6721 agtaacgctt ctttggcact aggagaagcc tatatggatc atcgaatcga gatcgaggga
     6781 agtatccaag cattgatcaa cgatgcttat cagcaagcaa acagcttttt acgaggaaaa
     6841 gattatctaa aatggctgcc aaagaaagaa aaacatacga aacaaaaaaa caaagaagat
     6901 atccatgcgc attatgactt aggtaacgac ttttataaac tttggctaga tccaactttg
     6961 acttattctt gtgcttattt caatacacct gaagatacgt tggaacaagc acaaatcaat
     7021 aaagtccatc atatcttaga caaactcttt atcaaagaag gcgaaacgtt gcttgatatc
     7081 ggttgtggct ggggaacatt gatgttcact gctaccaaag agtataatgt caaggcaact
     7141 gggatcacac taagtgaaga acaatacgat ttgattacca aaagaataaa agaagaacat
     7201 ttagaagata aatgccgtgt attattaatg gattaccgcg aactaaaagg cgaaacgttt
     7261 gatcatatca caagtgtagg tatgttcgaa catgtaggtt ctgaaaatct tgaaggttat
     7321 ttcaaagtgg taaaagattt attgaaacca aaaggaacag ctttgatcca tggaatcagc
     7381 cgacaacaag gcggtgcgac aaatgcttgg atcaataaat atattttccc tggcggttat
     7441 gtccctggtg ttactgaatt agttgataat attacaaaaa acgatttgca actgattgat
     7501 ttggaaagct tacgtcgtga ctaccaattg acattagaac attggacaaa gaattttcat
     7561 caagtccaag atcaagtcac gaaagaaatg ggtgattcct tctatcgaat gtgggatcta
     7621 tatttacaag cttgtgcagc ttcatttgaa tcaagtaata tcgatgtgat tcaatatttg
     7681 cttgttcaac ctggaaacaa tgacatccca atgcatcgtg cataattgag gcaaaagtac
     7741 tgtttaaaga ctatttaaaa agaagctaag ttttatgatg ctccagaagt gaactttttt
     7801 gtctaacttc taggattgtc tctaaagctt agtttctttt tctttatatt ttcataataa
     7861 aagtttggtt ctttaatttt taaacatgac agaaaatttt t
//
LOCUS       DADVXB010000129         7796 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.133, whole genome shotgun sequence.
ACCESSION   DADVXB010000129 DADVXB010000000
VERSION     DADVXB010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.133"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(112..630)
                     /locus_tag="KB902_002279"
     CDS             complement(112..630)
                     /locus_tag="KB902_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6809063.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(632..1249)
                     /locus_tag="KB902_002280"
     CDS             complement(632..1249)
                     /locus_tag="KB902_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6809064.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKFGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1246..2100)
                     /locus_tag="KB902_002281"
     CDS             complement(1246..2100)
                     /locus_tag="KB902_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6809065.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2097..3008)
                     /locus_tag="KB902_002282"
     CDS             complement(2097..3008)
                     /locus_tag="KB902_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6809066.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3049..4383)
                     /locus_tag="KB902_002283"
     CDS             complement(3049..4383)
                     /locus_tag="KB902_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6809067.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4591..5421
                     /locus_tag="KB902_002284"
     CDS             4591..5421
                     /locus_tag="KB902_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBB6809068.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5665..5947)
                     /locus_tag="KB902_002285"
                     /pseudo
     CDS             complement(5665..5947)
                     /locus_tag="KB902_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6105..6299)
                     /locus_tag="KB902_002286"
     CDS             complement(6105..6299)
                     /locus_tag="KB902_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809069.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6804..6989)
                     /locus_tag="KB902_002287"
     CDS             complement(6804..6989)
                     /locus_tag="KB902_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809070.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
BASE COUNT         2561 a         1519 c         1323 g         2393 t
ORIGIN      
        1 acaaaactta agttattaag acaaatgaat aaacaactac gctttcctcg aaacaaaaaa
       61 ataaagcaca aatgcgcatt tacgcactca tgctttattc gtacaattaa ttcagataac
      121 ggcagcgcat aggatgccaa taacacttcc taaaatagct cctcctaaaa tgtcagtagg
      181 ataatgtaaa agtaaaaaaa tcctcgaata agcgatcaaa caagcaaata aaaaggctaa
      241 tattcctgca actggactta attcgaacaa cgcagctact gataaaaagg ctagcgctgt
      301 atgtcctgaa ggaaaagaag aagtcttcgg tttacttgtg taaaggacaa gccgacgatt
      361 tttttcataa ggtcttttcc gtcttgtcgt ttttttgata aaaagcaaac caacaaaaaa
      421 atagatcaaa ctgccgataa gaatggctag accatattct ctagtatcag gtatcaagac
      481 taaaacagca gcaaggagca accaaataaa accaccatta gagatattac tgataaattt
      541 caaaaaattg atttttcgac tatccgtttt ccgttgcttg gcgaacttgt tgataatact
      601 atcatcgatt ttagcaatca aacgcaacat gttattcctc ctttttaaga accttttctt
      661 gcgtacgatg gataaaaagc aggacttgaa aataaaacaa gaaactgaaa cctaataaag
      721 caaaatagat tggtcctgca aaccagaatg cgacaagaag gatcaacgtg cctgccaaat
      781 agaaaagcgc gcttttgaaa tcattaaaaa acaagaaaaa tgcagtaatc caagaagctt
      841 ctttttgttc cagttgaagc aagattttgt aactaaagag aagcgcgctt aatagaagca
      901 aaaacaacgt agtatacatc aatgtatagc caattccccc accccaatag cggaaaatct
      961 gataatcgat caatagaaga agaaaataaa cacttgctaa actatcttgc tttccataaa
     1021 gagagaagtt ctcacgaaac tttttccaga atagtgaacc gaactttttc tcttcatttt
     1081 ttttgtaatg ataaatcata tacagaactg ttcgacttgc agttcctaat gtgaaaacag
     1141 gcaagacgca caggaaccat agtagctgta aatggataag acgtggaatc cattcaatga
     1201 tttctaagaa ataatcattg gcttttttac caatcgatcg attcatcatc cttttgaacc
     1261 tcctgtcaaa tccatccctt caatgaaata acgttgtgca aaaaagaaca gcaaaatcgt
     1321 cgggatcaag acaagtgttg ctcctgccat cagataattc cattgtgtcg ttgcttggtt
     1381 ctgaaaaact tgcaagccaa tctgtaacgt gtatttttct tgatcttgga tatataacag
     1441 aggacctaag aaatcattcc aagctgcgtt gaaggaattg atcgcaatgg taatcaaggc
     1501 aggtttcgtc aatggaagca tcaaatgact ccaaatatac aaatgattcg ctccgtcgat
     1561 ttcagcagct tcgatcaatt cattattgat cgataagtaa aattgacgca tcagaaatat
     1621 attgaacgca ttgccgaaga acgatggaac gatcaggggc aaataagtac ctacccagcc
     1681 gatcttggag aataatacat attgagggat catcgttaca aaccccggga tcatcatcgt
     1741 agaaagaacc aaagcaaaca tcagcttttt cccaggaaaa tcaagcttcg caaatccata
     1801 agcaataaaa gaatttgaaa ggacattacc gatcactact agcacagtga tgaataatgt
     1861 atttcttgca tagcgccaaa aaggaaaggc ggcaatcgta tccagatagt tttcccatac
     1921 gattttttct gggaaaaagg tcggaggata acgaacgatt tcttccattg gtttcaatga
     1981 agtaaacacc atccaaagca atggaatgat caaaatgatt cctattactg tcatgaggac
     2041 ataacttagt attttttttg tttgccgatt cacactggtc tttttgaaat aatccatcat
     2101 ttgccgtcac ctccagaata atagacccac ttaggtgcaa gcttcaaatt gacaaacgtc
     2161 agaaccaaca cgatcagaaa caggatcatt gacatagcca tcgcataacc catatcaaaa
     2221 gctacgaacg ccttgttcca catatgcaga ttataaaaaa gcaaagaatt tgcaggtccg
     2281 cctgttccat ttttcgtcat gacataagct tcttgaaaaa tttggaaaga accgatcgta
     2341 gaggtgatca catcgtaaaa aataatagga gtgattaatg gcaaagtaat acttttgaac
     2401 tttccccaaa cgcctgctcc atcgatttct gctgattcat ataaagatct aggaacattt
     2461 tgtaatgtag ctaagtaaag tagcattgct cctccagaac tccatatttt catcaaaatc
     2521 aacgcaggtt tcgtccattg tggatcaaac agccaagctg gtccagggat atggaaccag
     2581 cccagaaatg tgttgatcaa tcctgcagat ggagaaagca gctgcatcca taagatgtag
     2641 actgctactc ctgataagac tgccggtaaa tagaaagctg tacggaatac actgattcct
     2701 ttgatttttt gattgagtac tgtggctaaa aacacactga aaatcgtcgt cagcggtaca
     2761 ttgaagatga cgaaataaac ggtgttgtat aacgatttcc aaaataaatc atcgtgaacg
     2821 aacattcttt tgaaatttgc tagaccaatg aaattcatct tggatgtcaa attataatcg
     2881 gtgaaactac caataactga aaaaagcata ggccctagca taaataccaa gaacccgata
     2941 ataaaaggcg agataaataa ataggcccat cttgcttctt ttttctttcg gatagataaa
     3001 cgcttcaaat tttcttgcct cctctgtacc tagacagtca aaaatggatt attgattttg
     3061 cttgactaag ttttctactg ctttttgtgc atctgccaat ccttcttttg gtgattttgt
     3121 tcctaaaaga atctggtcaa tctgttcatt cactaatgtc gtgtaatccg gagcatctaa
     3181 aggaactggt gtgatcaccg tatttttaaa gttttcgtcc gccatttgat agatcatttt
     3241 tcctttatcc gttaggttgt cattattcac taaattctca ttggctgtct tgctcgccat
     3301 gatatcaaaa cttttttcgc cgaatttttc ttgtacttct ggagaagaaa gatatttgat
     3361 gaattcataa gaggcctcag gatcttttgc tccgtatggt acttccaaga cgaatccgcc
     3421 accccacgac caatggcctg aaccttcttc tttttctggg agctgcatca cgccaaaatc
     3481 aaaatcatcc ggtgcatttt ccatcaaact agagtaataa ttgatatttt gggcacgcat
     3541 ggctactaat ccggaaataa atggatcaga tacaccagac ccaaattcgg cttctaattt
     3601 attgatcgta tttttcccat aataatcttg ccagtcttgg atccactcca aggcttccac
     3661 tttattttta gtatcaatct tgactttttc atctttgtca aaccaactag tcccgttatc
     3721 tgcgtttagc gcccatacat cagcccctaa attccataat ggataaaaac cgatgcgtgt
     3781 aaattctttt ccttcttttt tatctagttt acgtgctgtt tcttctaatt catcccaagt
     3841 tgtcggtaga tcttgttcac tgattccagc ttctttaaat aactttttat tataaaaaat
     3901 gacttgtgta tctgtattga atgggatcgc ataaggatca ccttcatatt ctactgtatc
     3961 ccaaagctgc ggataaaaat ccttagaagt gtctttttct acatatttgg agagattagt
     4021 tgcttgctgt gcttctgctc tttgggcaac ggaatttatg tcctgtacaa taacatcggg
     4081 tgcatttcca gctgttattg cagataaaga tttagtccag atgtcacccc atggctgata
     4141 cttataattt acatggatct cgttttgtga ttgattgaaa tcctcaatga tttcttcgat
     4201 agcttctttt cgtgcaccgg atccccaaaa ggaccagaaa tcaatatttt ttcttccatc
     4261 acttgttttt tcagaagaat ttgctgcact tgaactggca tcgcttgcat tacttgatcc
     4321 gcatcctcct aataaaaaca atgctgaact tgccagcaac cctgtaaaca ataatttttt
     4381 catattttac ctccaaattt taatgtaacc gatgccggtt ttaatataac gatatcattt
     4441 tgttctgaaa ataacaattt ataaggtatg attctaaaaa aattattaat gataccaata
     4501 ctttatataa ttcgcgagcg ctttctttga attttttaat ctttcgtagc agaatgagaa
     4561 tgtattaaaa atagattagg aggaattttg atgtttagac accagaaaga attgcagttt
     4621 gaagcaaaac cagatcgtcc gaatccatta atcgcgaaat atctgcagga gctgatcggc
     4681 ggccaatatg gcgagatgag tgtagctatg cagtacctgt tccaaggctg gagctgccga
     4741 ggagaagaaa aatataaaga tatgctgatg gacattgcaa cagaagaaat cggccacgtg
     4801 gaaatgttgg cgacaatggt tgctcgttta ttagagggtg cgcctgttga agatcaagaa
     4861 gcagcgatgc aaaaagatcc aacaatcggt gccattatct ctggaatgaa tccacagcac
     4921 gcgatcgtag ctggcttagg acctcgtcct gctgacagcg tgggcaatcc atggagcggt
     4981 gcctatatca ttgcgagtgg caacttgtta gcagacttta gagctaattt aaatgccgaa
     5041 tcacaaggaa gacttcaagt agcacgtatt tacgaaatga tcgatgatcg tggcgtaaaa
     5101 gatatgctgt ctgttctcct tgcaagagat agctatcatc aaaatctatg ggaatgtgca
     5161 gtgaaagaat tagaagaaaa agaaggttca atcttagtcc caagtacttt cccgcgtgac
     5221 aaagaacgaa aagacattgc ttatgacttc tataacttct cagagggaga ccaaagtagt
     5281 gaaggttctt gggctagtgg caaagcactg gatggcgaag gcgaatatca atggttgaaa
     5341 gaacctaaga tcgaaggcgc tgcaccaaaa ttagaaccag taacaccaaa aatgtatggg
     5401 acacctccat tcaagaaata aatatctacc cgtagaaaca cccgtttttt gttccacacg
     5461 ctttgtgagc aaaactgact aaagtcatta atcataacca cccttcaaaa gggtggtttt
     5521 ctctagagct ataagctcaa atcaccggcc agcgcctaaa gacgctggct ttcatatttt
     5581 atgttcaagc catattgcct ttgccagttt tgcccacctc ttaaaaggtt tatgtactac
     5641 tccttagccc ttaaaaggat cgtcttactc tcgtacactc agcttatcta acgcactatc
     5701 atgtttttct tgttcttgaa tgtacttttt gatggtcgct tcattttgtc ctacttttgt
     5761 cacatagtat ccttccaccc aaaagtgtcg atacccaaat ttatatttta gatttgcaca
     5821 atctcttgat gatctcctga atattggctc gatattgatt ataaattatt tttcttctat
     5881 actttggtgt gaatacaatg tggtatttac acatctactt tgtacgggct aaactatttc
     5941 cctttattgc tccacccgca tagcaagtgg ttttgtattt caatcgctcg gcgcgctcaa
     6001 ttaggtctaa agacaataaa tctaaaaacc cgctgcttca ctgacagaaa caacgggttt
     6061 tcagaaaaaa atgaaatgaa aaagatctct tacggcaatc tattttattt ttttgatttt
     6121 ttataaatgg aaaatgcttc aagaagtcca agaaataaag ccgtataaaa acaagaacct
     6181 atgaaatctt tatttattag atattcaaca gaaatcccga taacactagc caacaatata
     6241 tttatcagaa gtgtaaaata aggatgcttt ttatagaata gaactagtgt tgttttcata
     6301 gactctcctt tcttcatatt tccaattaat cacaaattca cggcattact agaaaaatta
     6361 aaggggcgca gaagtggaaa aatactcttc gactttccct acaaaccagg ccatcttgtg
     6421 tttaataact ataccaaatc taaggtacct ctaaatctaa attccatttg tggcggtgac
     6481 ctccaatttt taactcttct atctcccatc cagtatacat aaccttgata cttcgaccac
     6541 ttatatatcg aacacacaaa tacctatcca ttgcaggagt actacctaac ttagttgcta
     6601 cttgcatcta aataacagct gaaaagatag gacttactct tagtaaagta tctgaactat
     6661 taatttttaa actatcattt ttatcctcaa ctacatgcac atctgttgca acttcacttt
     6721 ctgtctcatc cagataaatg attaaggaat cgggaattgc aatatcttca gctgacgctg
     6781 gaatagttga gctaaattag tcatcatatc tttattataa aataaccaac agcaaaaaat
     6841 acaatgaaaa acaaacttgg aactaatgta tcattaataa atgttgaaaa attcagcaac
     6901 tcattactgt atgattttag cagcccaacc aacatatacc ctataaaagc taataagatg
     6961 gttaggaatc ctttagaatt tttactcatt catagacact tccttaaata acttttatta
     7021 tagaaggtat tgtaaataat aatattgaca aaaagtgact caaaataaaa aaaaccttac
     7081 attatactgg aatgaactgt attgatagtg tacctaaaag ctctactgac ataagatcgt
     7141 gtaatcggta aagtaatttt attaattata cgggatgtaa tcaattagag aataaactaa
     7201 tcataaaagg tacttttaca ttcataattg tcgctttgag attctacttt ggttcactat
     7261 ctgacccaat tgcacatttt cgatcattac aagtattggt gtcgttagaa caactaaata
     7321 aaaactagcg gtagattttt cagaatctat gctaatttct gtatggatgt tccagtgatg
     7381 gcaaatttct cttttcattg tttttcttgt cgcatgatat gcctttttgt gttattcagt
     7441 taaactatag aaattctttc ctagacagat cttgatccca aattttacgt ttttgagcat
     7501 cgatatagtt taaaatgaca ttactcatat ctaaagagtt tagatttttt aggactaaaa
     7561 ctgtcagttg ttctttttct tctttctgtt aaagtattgt cgcgactttt cgtatacgtt
     7621 aagatatgtc gtgaaaaaac aagttttgtg acacaaaaaa acgaatgact tgaggaaatc
     7681 acctcaatca ttcgtttaaa atgctatata ttctttagtt taagatacgg aaattaatgc
     7741 catcgaccac actagtagaa tgaacgacat ttacttggcc tttttttaat ttcgtt
//
LOCUS       DADVXB010000130         7763 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.134, whole genome shotgun sequence.
ACCESSION   DADVXB010000130 DADVXB010000000
VERSION     DADVXB010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.134"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            357..659
                     /locus_tag="KB902_002288"
                     /pseudo
     CDS             357..659
                     /locus_tag="KB902_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2433..3200
                     /locus_tag="KB902_002289"
     CDS             2433..3200
                     /locus_tag="KB902_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HBB6809071.1"
                     /translation="MVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGIKEACEE
                     LQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGVELLEDN
                     AQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKRTPDDNP
                     IIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLDLFSFDD
                     EVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            3178..7575
                     /locus_tag="KB902_002290"
     CDS             3178..7575
                     /locus_tag="KB902_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HBB6809072.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDGMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
BASE COUNT         2683 a         1190 c         1680 g         2210 t
ORIGIN      
        1 ctgctgagaa aattcctgta gactataatt ttaaaataac taaagacaga gtaatagaac
       61 tacaaaaaaa tggtgaaatg gtggatttta agtatactct aagacataaa aaatttgatt
      121 caactacatt tcgttcaatc atgatatcaa aagatgaatt agttaaagcg attccagaat
      181 taaaggaaac cacgggaata agcaatataa cgttcatgcc tattgacggt gaaaaagata
      241 aattaactgt gttggtaaat ttggatgaac acttatcaac agccactctt tataggacta
      301 cgaaagatga gagtccaatt ggtaaggtag aaaagaaaaa cgatacaata tcaagacaaa
      361 ctgtagataa aaaaattgat acgttcataa aaacatacgc ggctatacca cctacttgga
      421 aacttgtaaa tgaagataag ggaataacga taaatactga tacagagatt ccgactgatg
      481 ctcaatcttt atcagattta ttagctaatc taacaggagt cagtaatgcg gtgtcagagc
      541 aagtcggtaa agatattcca cttaggttac ttgaaaatgg aaaaaaagat tattctgtgg
      601 tatttaagaa cggaaaggta actgattaca acgaaatatt tgagaaagtc attgaataat
      661 ggtttttcta tctttttatt aactacccta ccccgttgtt ttttgaccgt gtttcgagag
      721 gaatcattag aaagcatagg ctaactaggg gtttcttttt cttttatttt ttgggaatcc
      781 gcttaagtga aatgtatctg aaatgaaacg gagataaagt gattttttgc tgtaatgaca
      841 aggttttagc tgtttcagat accatgtaac ccaaaatagt ttattgagaa aataggagag
      901 tatttgatac taactagtag ggaaaaatga gataaaaagt aaatggaatc atttcaggta
      961 atctgaaata aaaaaatata cagtcctgtg gcactttacc tatgggactg tatatttttt
     1021 actctcagcg ttttttgact ccgtgtctga ctccgtttta ttgattttat atgttattca
     1081 gtgacccttt aacaggtcaa tttttatgtt tttgtcttcg tatgactcag tttgatacct
     1141 agtgatttcc atggtaatac gggatgttga acaagctaga gaagttctgc aggggttaat
     1201 tgcaaacaat tcagataaac aaattacaat agattatttc aagagggaaa ttaaaaaatc
     1261 agaggaaaaa tatttagatt taaagtcgga tatcctatta gcagacgata taggttcact
     1321 aactgtcgaa gaagatagcc tattctacgt ctattgtgca ttgacttcgt aaaagaagac
     1381 gtcttttcca ggtatacagt tcttttatct acttcatatg aaaatttggg tacaaacgac
     1441 aaggaagtca gttttctggt cagactatcg tacgaacatc ttgttgtggt atttacactc
     1501 agctttgatg atgagtacaa gagtttttca gcgaacaaga cagaacatcg aaagaggttt
     1561 ccagacgaag ttttacaggc tgggctgaag tattatcaag aaggactcac cattaagaag
     1621 tctttatcga gaatataaga agatacaggt atagaagtca gtcggtcaac attctgtgat
     1681 tacctaaaca gcaaggagta acaggtgaac gggaaaaaga gcacagggag ggctatgttc
     1741 actggctgaa gaagcaagat aaacctgttt atgacttgtt ctttgaaata aagaaagctt
     1801 tagatagtca gtcattagag aacttcattg atgggtatga tgaaaagtta tctaatgagc
     1861 aaatgattgc gataatgaaa gaggtgtttc gtcagtatgg gttatcaaat aaacgtagga
     1921 aagaggtttt tgaccacgtt aagacaataa tgagctttta ccacacgacc ctcggctaaa
     1981 tctaaagagg gcgaaaaagg gacgagtggt aaaatttaat gggaatagct aaaagtaaat
     2041 aataataagt caaagactgc ctagtttggt ggtctttttt catgttcata aaaataaaat
     2101 aggacagacg aacatcttcg ctaactcccc tgtgttgcaa gaggcaaact ctataattct
     2161 ccagttaagc tatattttgt tctttatttt gagatagagg aaaaaacaaa aatgtgttaa
     2221 aattgaacat aagcataatt agaaattgtc gagttttttc aagtaaaaat cttgacttgt
     2281 aaggaggaaa agggcatgat gacacgcaat cacagtacta gccagcagtc tgcccaaaag
     2341 cccatatatg aaagtgataa ccgattcgta gcatccgttt cggttatttg tgttgggaag
     2401 atgggtgatt tttagtggtt gaagatatgg tgatggttga agaggaacaa ggacgactaa
     2461 tcaaaagtaa aaaacgtgtc cagaagcacg gtgaggtatt tacaccgcaa agaactgtca
     2521 aagatatgtt ggatttgcca ggcataaaag aggcttgcga ggagctgcag acgactttct
     2581 tagagccttc agctggagaa ggtgctttct tagttgaggt tttgactaga aaaatggcaa
     2641 tggttgctcg tgaatataat gagtccctag aacagtatga aaattactcc ttactggcgc
     2701 tttcaactct atatggcgtg gagttactcg aagacaatgc tcagacctgt gtaatgaaca
     2761 tgtttcaagt attcaacgat ttgtacagag aacaatcgaa aaaacatggt accgcaatga
     2821 aaaggaaagt ccaagacagt gcaaagactt tgatttctag gaatatcaaa cagggagatt
     2881 ttcttacaaa acgaacacca gatgataatc cgattatttt tagtgagtgg acacctaaga
     2941 cgctaagaaa aggacagaaa aaaatcactg taaatcgaac tgaatattct ttggaggata
     3001 tttattcagg ggtaacacga gagtttggag aggcatactc agctctgcct gtatttgaac
     3061 agctcgattt gttttcattt gatgacgagg tcgatgaaga agtttcaaat gatccaatat
     3121 tacgttatgt agcgatgccg ataactgagg tttataagga agagatggag gaaattgatg
     3181 acgacagcgt tgaaatctaa agctaaatac ttcgattact tacctaaata tggttctaag
     3241 ctagaacact tccttgggat tcctaattta gtagatgcaa ttaacacgta ccgtgtaacc
     3301 gttaatcaaa tacctaatga agttgctatt ggaactagac gttattcgga ggtagcagca
     3361 cggaagattg cttcaaatgt gggtattgac cagcaaagta tgaagtatgt tgatgtactt
     3421 cgcgagctta gggtcagaaa taatattact cctacgatag ctgacttatt tcataagttg
     3481 agaaaatatg gaaatgttgc agcacatgaa aatggaatta tacctgtttc agaggcggtc
     3541 gaatctttag ttactcttga taccttgcta agagtctttg cacgcaatct gtctggggat
     3601 aaatcgttaa acccaaagga agaaattacg gatgagatgt ttgttatcac ctataacacc
     3661 tttgaccgta aacttattta catccagagt gccaaggatg ctgacggcac atggaaaatg
     3721 taccaaggac tggaaaagat tggggatgca tcagtaccag agaattatga ggcagacttt
     3781 actcctaata gcgagtattt aagagagtat gcaagtagaa gaataaagca gtacatgaca
     3841 acagcggggg taccttttgt ccttcattgg gcgcaattgg ctgttaataa gaagaaccaa
     3901 tttttccgtg accatgacgt gcatgaagta ttaaagcgtt cgggctataa tcctcaaacg
     3961 attggcgaag atgacacagg gaagcctaat gagtggttca gtgtaacagt tgacgttgcc
     4021 aagaaagcaa tccaagcggt taaagatggt aaaggtagtc ttgactcaga aaaagatgac
     4081 tttgacgagt tcaaaattaa ttttagacca gaacaaaaag atgctattga gcagactaag
     4141 actgtattca aaacgaaaga tgagatgctt tggaatgcca agatgcgttt tggtaagacg
     4201 ctttcttctc ttcaagtgat taaagagagc caatacaaaa aagttcttat catgactcat
     4261 cgacctgttg taagtgatgg ttggtttacg gatttcaaaa aaatcttcac agatggttcg
     4321 tacatctatg gttcaaaaca agatggagaa aagattcaaa accttgttga taccgaaaaa
     4381 cctttcatct attttgcaag tattcaggac ttacgcggtt ctgagtgggc aggtggaaaa
     4441 gcaggggata aaaactatga attcttagcg attgactggg attttattat tattgatgaa
     4501 gctcacgaag gaaacgaaac ggaattagct aataacgtaa aggctaagtt gcggaaagag
     4561 cataccaagg tcttagagct ttcgggtaca ccatttaacc ttttcgataa gtatgatgag
     4621 gataatattt tcacttggga ttatactatg gagcaagaag ctaaggagaa atggtcagta
     4681 gagcatccca atgaacctaa cccatacgaa ggtttaccga aagtatctat gttcaccttt
     4741 gaaataccaa ataaatttga ttatttcgat gaaaataagg catttaactt ccgagaattc
     4801 tttagggtta aggaagatga tgaaacaaag ttgcttcatg aaggtgacgt acgcaagttt
     4861 cttgattata ttactacaaa cgatgaaaag actaattttc ctttctcaaa accagagttt
     4921 agagaaaact tacggcatac tttatggctg atgccggggg ttaaagaggc aaatgctttt
     4981 gaaagagtgc tcgaaacgca ccctatattc aaagattaca atattgcaaa cgtagtcaag
     5041 acaggtgaca gtgagcatgc tagtgattca gatttagaat tggtgcgtaa agctattggt
     5101 aatccagcta agtctaagac gataacctta acagttcgca agcttacaac aggagttaat
     5161 gttccagagt ggacaggggt atttttcctt tcaaacacag aaagtcctac atcttatctg
     5221 caggcagcgt tccgtgcaca gacacctttt aaccatgcag agcttggaat taagaaaaac
     5281 tgctacatct ttgattttgc acctgaccgt gctttaaaaa ttatgagtgg aagtgtcgga
     5341 ctaactagca agaagggaaa ggttaatagt tcagagcaaa agaaaaaact agagcgcatg
     5401 ctaaatttct tacctatcct tggtaaacag gggaatgtga tgaaagaatt tagcgttgac
     5461 ggaatgctta cggcactgaa gaaggcttat gcagaaaaag ctgtacggac tggctttgaa
     5521 gacagctctc tttacaatga caacctatta aatttagacc aagctgatct taccaaattt
     5581 gaagacctta aaaaaattgt tggctcaagt aaaccaacca aagtgaaaga cttcattgtt
     5641 tcagataacg gtatgagtga agaggagtat gaaaaagctt cgagggcaga aaagaaacca
     5701 aaacgtcaac gtaccaaaga ggaacaggaa gcaatagata gggcaaagag gcttcgagag
     5761 cagcgaaata aaatgatttc cattttgagg ggcgtttcta ttcgcatacc tatgatgatt
     5821 tatgggatgg acattgatat taaagatgac gttactattg agatgtttct taatttggtt
     5881 gatgaggctt catggaatga gttcatgcca gaggggttaa gtaaagggcg attcagagag
     5941 tttattgagt actatgatgc agacgttttt gtggaggcag gacgcataat ccgtagacgt
     6001 gcaaagtctt atgatgagtt agatgttatt gaacgtacta ggaaaatagg tgaattattt
     6061 agcactttta aaaatccaga caaggaaacc gtattgactc catggcgagt tgttaatatg
     6121 caccttggta acactatcgg tggactttcc ttctttgatg aagaatacca aaattctacg
     6181 gagaacggtc aaccaatcgt gcgatggagg aaaactgact gtacagatga tatttttaag
     6241 gaaaatagaa agattcttga gataaactca aaaacagggc tatatccttt atatgcagca
     6301 acgagtatgt actatgttca gctccttaaa caaagcgata ttaatgctgg aagggtagat
     6361 tcagaggcaa tatgggaaaa agtattatca gagcaaattt ttgtcatttc taaaactcca
     6421 atggctaaga cgataacgaa gaggactttg attggttata acgcatggaa ggtaaatgtt
     6481 gaatactcaa gtgaattagt tacgagtatg aaacgttcaa tcaatgacgg tttaacgaat
     6541 ttgaaaggag tttataaaaa cgtgaaattt gatgtgataa ttggtaaccc accttatcag
     6601 gagaaagatg gaggttcagg agctagtgct acaccgctat ataatctatt tgtagaaacc
     6661 tctgttaagt tatcagaacg ctatgtttcg atgattactc cttcgaagtg gtttgcaggt
     6721 ggtaaagggt tagataagta ccgtgacttt atgcttaaca gctctagctt gaaggtgatg
     6781 gtggatatag taaatgggaa agaaatattc ccaaacacca gtattggtgg cggtgttagc
     6841 tatttcttgt gggataagaa atataatgga ttgacacagt atactaatca acatgatggt
     6901 gtatcaaata cacaagagcg aaaaatgaac gagtttccag tgtttgtgcg atataatgaa
     6961 gccatttctg caattcacaa aattggggaa cacgctagtg ttggtgactt tgttatatca
     7021 cgtaacccat ttgggcttcc aacgaaaatt cgaggggaag aagtgcagga ttccagaaat
     7081 tcaataaaag taatctctag tggtggggta ggctttgttc cactggaaga tatcactaaa
     7141 ggacaggata tggttggaaa gtataaagtc attagtagct cactgactag cgaacatgca
     7201 ggtgaaccga acaaaaatgg tatgtttaag gtgatttcta ctaacagagt tattaaacct
     7261 aatgaagtag ttacagattc atacctagtg ctattttctg ctgataccga aaccgaagca
     7321 attaattatc tgaagtattt acgaacacgt ttttacagat ttttattact tcaagcagtg
     7381 acatctattc acctatccaa agataagttc atgttcatac cagtacaaga ttttacctca
     7441 ggttcagaca ttaactggaa tgtaggtatt gaagaagttg atatgcagtt gttcaagaaa
     7501 tattctttcg atgcaagtga gatattgttt attgaccaaa caatcgtccc gattcttcac
     7561 gaggaatatt actaagagaa caagctaaca aatgaggctt agaaccctgt tttcttgatt
     7621 aattgcccca ctttaaatca agatttaact gtctattatc aacaggtcaa ggtaaaataa
     7681 aggatgttag caagtaaaga gattgatttg agtctacatc gaacaaggga ataatccaat
     7741 aaaaaatgat ttagaatatc aaa
//
LOCUS       DADVXB010000131         7688 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.135, whole genome shotgun sequence.
ACCESSION   DADVXB010000131 DADVXB010000000
VERSION     DADVXB010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.135"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            152..2095
                     /locus_tag="KB902_002291"
     CDS             152..2095
                     /locus_tag="KB902_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809073.1"
                     /translation="MLSKRESQLIELLLEEENFQPASFFSEKLNVSNKTIYQDIQKLG
                     QFLNRFELKIEKKPRMGIYLIGTSTKKNDAKIFITSKEAMSTKVKYSSNYRRVYLFAN
                     LIFKTDKKRYEYFEKKFFVSIATLRKDYEEIIKYCRLAGIRITSNHVIDTQKTPEELI
                     QRTFVNYFEKNIGVGNEKCQYHFVFDQAMVKFVDDFVKNFYQQSKQQPTNYIVHSLKL
                     SLLTLIGRVKHGYHSQTNKNPLFVEIKKMELYMVALDFSNGVKDELNCSFTINDLYFI
                     CSLFMGHGVRPFVNLATHSQQIMETTKQFIQDMSTLVEKDLGQDSQLLQSLFAHIEPM
                     VYRLQMGITIKNPLKEDIIRQYSTMYTLATYCIPKLEKAMGIRVTDDEITFLTIHFQL
                     AFEKIVNTKHVFLICPTGLGTSQLLFQRIRHSSPSTVVYEVIDVQKLQDYNLDSVDLI
                     ISTVKLENEYQTPVIYVRPLPTKEEIALINRHLLTLNQQDNTFLPSIAPDKTILKKYL
                     KDGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFIEVVLQREKLGATGLSSGVAIPH
                     ANPKYVVKTKISIITLKNKITWGDVDIRVVLFLAIAEEDMIQVKNMIALLYDVFVSPE
                     RIKSIASKETRNEIINEIIGKRK"
     gene            2097..2558
                     /locus_tag="KB902_002292"
     CDS             2097..2558
                     /locus_tag="KB902_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6809074.1"
                     /translation="MTSYFGKKIALFQSEVKSQKEALSIIATCLYQTGLVKDSFAENV
                     LKREEVFPTGLLINDVGIAIPHTDAEHVNDSQIAFMSLKTPVTFYEMGTADKEISVSL
                     IFMLALKEPHAQLEMLQKLITMFQKKEVVQKLRAVNNTEEYYQIIEKEGFV"
     gene            2582..3928
                     /locus_tag="KB902_002293"
     CDS             2582..3928
                     /locus_tag="KB902_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6809075.1"
                     /translation="MLDLLQKFVDLGSIVVLPILIFVFGLILGTKPSKAFISALTVGV
                     GFVGLNLVIDLLTNSLGPAAQAMVERFGLNLTTIDVGWPAAAAISYGTVLGSLAIPVA
                     IVVNVLLIIVGLTKTLNVDIWNIWHAAFVASLVYAVTNDFAMGMLATVIYTMMILLFG
                     DILGPIINKFYGFPNITFPHGTSAPGFVFALPLNWLFDRIPGLKDWHADPETIQKRFG
                     IFGDSTVMGFLIGLVMGILAGYDVAGIGQLAVKTGAVMVLMPKMVALLMEGLTPISES
                     ANSFVQKRFPGRELYIGMDAALSVGHPAVLSSSLILVPITILLAVILPGNTTLPFGDL
                     ATIPFLICLMAAVFGGNIIRTILGGTIYMVTILYITSWVAPFLTKAAQGANFDLQGHS
                     SVTAMAEGGLWTTLLYVGGAKLFGYFALVGIGLIITGLLFYVNRILPKRAAKQTEA"
     gene            3951..4235
                     /locus_tag="KB902_002294"
     CDS             3951..4235
                     /locus_tag="KB902_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6809076.1"
                     /translation="MKKLLIMCGTGVATSTVVTGKVKEWLKSKGLENEVKLYQSKVAD
                     EIGKIDDYDIVVSTTVVPDNIKDKVIMGLPLLTGIGIDGLFDEIEAKIKA"
     gene            4262..5089
                     /locus_tag="KB902_002295"
     CDS             4262..5089
                     /locus_tag="KB902_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HBB6809077.1"
                     /translation="MLVTTKEMFEKAQKENYAIPAANFFDLDSARTFVEVAEKMQKPL
                     ILAFAQAHIEECPLEEAALIATYLAKKASVPVALHLDHGQDEEIIKQAIELGFTSVMI
                     DASQDEIETNIRRSKAIAEYAHERGVVVEAEIGHVGTGNSYEFKETTDTIYTEVEEAA
                     RFAKETGVDSLAVSIGTAHGQYKGTPKISFERLEEIKNEVSIPLVLHGGSSSGDENLH
                     KCAVSGINKINIFTDFITAAMDVINEEKPEDYFTLKRLANQAIADTLSHYYEVFATK"
     gene            5102..5797
                     /locus_tag="KB902_002296"
     CDS             5102..5797
                     /locus_tag="KB902_002296"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6809078.1"
                     /translation="MRTVRKPFFVVNPKSYLYGEQALKLAKTADQLAAAYDIDIIFTC
                     QHVDVRLIKEQTTQLIVSVQHIDGIVPGRGMGHVLPEGVVAAGAEATFLNHAERPLSV
                     SELCDAVKRAKELGLLTIVCANSLEEAKLVASLKPDVMVCEPTELIGTGQASDISYMI
                     QTNEAVRKMDPEIFVLQAAGISTVADVRKALDSGADATGGTSGIVCAKDPVDTLKAMI
                     EEVSKWKKEQSTK"
     gene            5794..6309
                     /locus_tag="KB902_002297"
     CDS             5794..6309
                     /locus_tag="KB902_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016380999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBB6809079.1"
                     /translation="MITYTEQLVLTSNGQRVTYHNITEQVKEIVAKSGIKNGICLVQS
                     PHTTCSVIFEEFMHDLDFNGDEFLQVDLNRILDRIIPRELTENTDYRYPGPKHLDFLL
                     SLDDPDYAGDAGTILNGDAHIRASFFGASENFIVKEEILMTGTVGSIYFIDFDQNRVR
                     NRKCHILVMGE"
     gene            complement(6436..7608)
                     /locus_tag="KB902_002298"
     CDS             complement(6436..7608)
                     /locus_tag="KB902_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBB6809080.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT         2466 a         1202 c         1602 g         2418 t
ORIGIN      
        1 ttaaaaaaat tgtcgtgagt tttactgaca tcaaaaagta tagggtcata ataatctgtt
       61 ccacattaat gtggaacaga ttacgtattg atctttagtg agaaaaactc tatgatatag
      121 acaaggaaaa cgttttctga ggtgatgatg aatgttatca aagcgcgaga gtcagttaat
      181 tgaattactt ttagaggagg agaattttca accagcaagt ttctttagtg aaaaactcaa
      241 tgtttcgaat aaaacaattt atcaagatat tcagaagctg ggacagttcc tgaatcgttt
      301 tgagttaaaa attgaaaaaa aacctcgcat ggggatttac ttaattggaa cgtcaactaa
      361 aaaaaatgat gccaaaatat ttatcactag taaagaagct atgtcaacaa aggtaaagta
      421 tagttcaaat tatcgtagag tgtacttatt cgccaatcta atttttaaaa cggataaaaa
      481 aagatatgag tattttgaaa aaaagttttt tgtcagtatt gcaactttgc gtaaggacta
      541 tgaagaaata atcaaatatt gtcggttagc tgggattagg attacttcaa atcatgtaat
      601 agacacacaa aaaacacctg aagagttgat ccagcggaca tttgttaatt attttgaaaa
      661 aaacatcggt gtagggaatg aaaagtgtca atatcacttt gtttttgatc aagcgatggt
      721 taagtttgtg gatgattttg taaaaaattt ttaccaacag tctaagcagc aaccaacaaa
      781 ttatattgtc cattcactca aactttcgtt gttgacgttg attggtcgag taaagcatgg
      841 ctaccattca caaacaaata aaaatccttt gtttgtcgaa ataaagaaaa tggaattata
      901 tatggtggca ctagattttt caaatggggt caaagatgaa ttgaattgtt cctttacgat
      961 aaatgatctt tactttattt gttcgttgtt tatgggacat ggagtgagac cgtttgtgaa
     1021 tctggcaacc catagtcaac aaatcatgga gaccaccaaa caattcattc aagatatgtc
     1081 gacactggtt gagaaggatt tggggcaaga tagtcagctg cttcaatctc tatttgccca
     1141 tattgagcca atggtttatc ggttgcaaat ggggattacc attaaaaatc ctttaaaaga
     1201 ggatatcatt cggcaataca gcacaatgta tacgctagca acttactgta ttccaaaatt
     1261 ggaaaaagca atggggatca gagtaacgga tgatgaaatt acttttttga ctattcattt
     1321 tcagttagct tttgaaaaaa ttgtgaatac gaagcatgtt tttcttattt gtccaacggg
     1381 gttgggaact tcgcaattat tatttcagcg tattcgtcat agttctccta gtaccgtagt
     1441 ctatgaagtg attgatgttc aaaagttgca ggattacaac ttagatagtg tcgatttgat
     1501 tatttcaaca gtcaaattag aaaatgagta tcaaacgccg gttatttatg ttcgaccatt
     1561 accaacgaaa gaagaaattg cattgattaa tcgtcatctt cttaccttga atcaacaaga
     1621 caatacattt ttaccatcca ttgcaccgga taaaacgatt ttaaagaaat atttgaagga
     1681 tggttggatg tttttgaatc aagattttga tagtagagaa tctgtacttt ctttcatcac
     1741 tgagaaatat aaagaagaac aattagtaaa ggataatttt attgaggttg tacttcaaag
     1801 agaaaaacta ggagctaccg gactttcatc aggcgtagcc atcccacatg caaatcctaa
     1861 atatgtagtc aaaacaaaaa tttctattat cactctaaaa aacaaaatta cttggggaga
     1921 tgtggatata agggttgttt tattcttagc gattgcagaa gaagatatga ttcaagtgaa
     1981 aaatatgatt gcactacttt atgatgtctt tgtctcacct gagagaataa aaagtattgc
     2041 aagtaaagaa acaaggaatg agattattaa cgaaattata ggaaagagga agtaagatga
     2101 cgagttattt tggaaagaaa attgcattat ttcaatctga ggtaaagagt cagaaggaag
     2161 ctttatcaat tattgcaact tgtctatatc aaacaggttt agtgaaggat tcgtttgcag
     2221 agaatgtact gaaaagagaa gaagtgtttc ctactggctt attaatcaat gatgttggga
     2281 ttgctatacc acatacggat gcagaacacg tgaatgattc tcaaattgca tttatgtcat
     2341 tgaaaacacc agtaactttt tatgaaatgg gaactgcaga taaggaaatt tcagtcagct
     2401 tgatcttcat gttggcgttg aaagaaccac atgcacagtt agaaatgtta cagaagttaa
     2461 ttacgatgtt tcaaaaaaaa gaggtggttc aaaagcttcg agctgtaaat aatactgagg
     2521 agtattatca aattattgaa aaagaaggat tcgtttaata accattttga gggggagcat
     2581 tatgttagat ttattacaaa aatttgttga tctcggatca atcgttgtat tgccaatctt
     2641 aatttttgtt tttggtttga ttttaggaac aaaaccgagt aaggctttta tttcagcatt
     2701 aacggttggt gttggatttg tcgggttgaa tttagttatc gatttattga ccaatagctt
     2761 aggaccagca gcacaagcga tggttgaacg ttttggacta aacttaacaa ccattgacgt
     2821 tggttggccg gcagcagctg cgatttctta tggaaccgtt ttaggtagtt tggcgattcc
     2881 agtagctatc gtagtcaatg tgttattaat tattgttggc ttaacaaaaa cactgaatgt
     2941 tgatatttgg aatatctggc atgcagcatt tgttgcttca cttgtctacg cagtaacgaa
     3001 tgactttgca atgggcatgt tggcaacggt tatttataca atgatgattt tattgtttgg
     3061 cgatatttta ggaccaatca tcaataaatt ctatggattt ccaaatatta ccttcccaca
     3121 cggaacatca gcacctgggt ttgtttttgc cttaccttta aattggttat tcgataggat
     3181 tccaggattg aaagattggc atgcagatcc agagacgatt caaaaacggt ttggcatctt
     3241 tggtgattca acagtcatgg gctttttaat tggtttggtt atgggaattt tagctggcta
     3301 tgatgttgcg ggaatcggtc aattagcggt gaaaactggt gctgtaatgg tcttaatgcc
     3361 taaaatggtg gcacttttaa tggaaggctt aacacctatt tcagaatcag caaattcatt
     3421 tgttcaaaaa cgtttcccag gaagagaatt atatatcgga atggatgccg cattgtcagt
     3481 aggacaccca gctgtattgt cttcttcgtt aatcttagtc ccaatcacga ttttattagc
     3541 agtgatttta ccaggtaaca caaccttgcc tttcggtgat ttggcaacta ttccattctt
     3601 aatttgtttg atggcagctg tctttggtgg aaacattatt cgaacaatct taggtgggac
     3661 gatctacatg gtcaccattt tatacatcac ttcatgggtg gcaccatttt taacaaaagc
     3721 agcacaaggg gcaaactttg atttacaagg acattcatca gtaactgcga tggcagaagg
     3781 tggactgtgg acaacacttc tatacgtggg tggtgcaaaa ctatttggct actttgccct
     3841 agtcggaatt ggtctgatta ttacaggctt actattctac gtgaatcgca ttttacctaa
     3901 aagagcagct aaacaaactg aagcttaata caaaatagga gagatgacag atgaaaaaat
     3961 tattaattat gtgcggaaca ggtgtggcta cttcaacagt ggtaacagga aaagtaaaag
     4021 aatggttgaa atcaaaagga ctcgaaaatg aagtgaaact atatcaatca aaagttgctg
     4081 atgagattgg caaaattgat gactacgata ttgtggtcag tacgaccgtg gttcctgaca
     4141 acattaaaga taaagtaatt atggggcttc ctttattaac cggaattggc attgatgggt
     4201 tgtttgacga aattgaagcg aagattaaag cctaaaaaat acttgaaaag aaggtaatca
     4261 aatgttagtt acaacgaaag agatgtttga aaaagcgcaa aaagaaaact atgcgattcc
     4321 ggcagcaaac ttttttgatt tagattctgc aagaaccttt gtagaggttg cagaaaaaat
     4381 gcaaaagcca ttaattttag cctttgcaca agcgcatatt gaagaatgtc ctcttgaaga
     4441 ggcagcgtta attgcaacat atttagccaa aaaagcaagt gttccagtag cacttcattt
     4501 ggatcatgga caagatgagg aaatcatcaa gcaagcaatc gagcttgggt tcacttctgt
     4561 gatgatagat gcttcgcagg atgagattga aacaaatatt cgtcgttcaa aggcgattgc
     4621 ggaatatgct catgaaagag gcgttgtggt agaggctgag attggacacg tgggaacggg
     4681 aaatagttat gaatttaagg aaaccacgga caccatttat accgaagtgg aggaagcagc
     4741 acgttttgcg aaagaaaccg gcgtcgattc attggcagtt tcgataggta cggctcatgg
     4801 gcaatacaaa ggaacaccga aaatcagctt tgagcggttg gaagaaatta aaaatgaagt
     4861 ttcaattcca ttagtgttgc atgggggctc atcatctggt gatgaaaatc tccacaaatg
     4921 tgctgtttca gggatcaata aaattaatat ctttactgat tttatcacag cagcaatgga
     4981 tgtaattaac gaagaaaaac cagaggatta ttttacactt aaacgattag cgaaccaagc
     5041 gattgcggat acgttatcgc attattacga agtatttgca acaaaataga ggagggttct
     5101 catgagaaca gtaagaaaac cattttttgt ggttaatcct aaatcttatt tgtatggtga
     5161 acaggcattg aaactagcaa aaacagcgga tcaattagct gcagcatacg acatcgatat
     5221 catttttact tgtcaacatg ttgatgttcg gctaattaaa gaacagacaa cgcagttgat
     5281 tgtgagtgtt caacatatcg atgggatagt ccctggtaga gggatgggac acgttttacc
     5341 tgaaggcgtt gtagcggctg gagcagaagc gaccttcctt aatcacgcag aacgtccttt
     5401 atcggttagt gagctgtgcg atgccgtcaa gcgagcaaag gaacttggtc tattgactat
     5461 tgtttgtgca aattctttag aagaggctaa gctcgtagct tccttgaaac ctgatgtgat
     5521 ggtttgtgag cctacggaat taataggtac aggtcaagca agtgacattt cttatatgat
     5581 tcaaaccaat gaagctgtac gcaagatgga tcctgaaatt tttgttctgc aggcagcagg
     5641 gatttcaacg gtagcagatg ttcgcaaagc acttgattcg ggggctgatg caacgggtgg
     5701 aaccagcggg attgtttgtg ccaaagatcc tgtggacaca ttgaaagcga tgattgaaga
     5761 agtaagtaaa tggaaaaagg agcaatcgac aaaatgataa cttatactga gcaacttgtt
     5821 ttgacttcaa atggacagcg agtgacgtat cataatatta ccgaacaagt aaaagaaatt
     5881 gtggcaaaaa gtgggataaa aaatggcatt tgtcttgttc agtcgccaca tactacttgt
     5941 tcagttattt ttgaggaatt catgcacgat ttagatttta atggggatga atttttacag
     6001 gttgatttaa atcggattct tgatcgaatc attcctcgag aattaacgga aaataccgat
     6061 tatcgttatc ctggtccgaa gcatcttgat ttcttgctgt ccttagatga tccagattat
     6121 gctggtgatg ctggaacgat tttaaatgga gatgcacata tccgagcatc attcttcgga
     6181 gcaagtgaaa atttcattgt caaagaggaa atactaatga caggaactgt cggctccatt
     6241 tatttcattg attttgatca aaaccgtgtt agaaatcgaa aatgccatat tttagtaatg
     6301 ggtgaataga aaagtaataa gaaacaaaca tttgggaaac taattgaatg atcacaccta
     6361 taaaaattaa tacgaaagat aatagagtca agtccagact cctgtgtaaa atgctataca
     6421 atgtttttac catttctact tatcaaaatt gatgtatttt cttgaagaat aaatccattc
     6481 atcatgcagg tccataagaa cggctccaat taagcgattg gctgatgttt gattggggaa
     6541 gatgcgaata atcttttctc ttctgcgtac ttcttgattc agtcgttcaa ttagattggt
     6601 actctttagt cgattgtggg aatttccttg tacggtatat tgaaaggcgt cttcgaatcc
     6661 atcatccaat gatgcgcaag cttttgaata ttttggttga tcgatataat catgaatcaa
     6721 tcgattttta gcctcacgcg ctaagttaat atctgtgaac ttaaaaattc ctttaacagc
     6781 ttctctgaaa gattttgaat tttttttagg aatggtggta aagatatttc ttaggaagtg
     6841 aacttggcat ctttgccaac ttacgttggt gaaggatttt ctaatggcag agactaatcc
     6901 tttgtgcgca tcagaaataa cgagttccgt accttgtaaa ccgcgttctt ttaggtattc
     6961 aaaaaatgtt gtccaggtct cttcgctttc gccactttga atcatgaagc cgataatttc
     7021 acggtcgcca tctttggtta ttccaatcgc tatatgacag ctttttgaga gtactcgatt
     7081 ttcttctcgt acttttatat agagtacatc ggtcattaag taaggataat ttttttctga
     7141 taataaacga ttctgccact cgttaaccat aggttctagc tgttctgtta agctagaaac
     7201 gaaggactta gagacggatt taccacaaag ttcttccaca atttttgata ctttacgagt
     7261 tgaaacgcct gatacataca tttccaacat tgaagccatg agggcttttt cgtttcgttg
     7321 ataacgttca aacactgtgg gtgaaaaatg gccatcacgt gttctgggta cttttaattc
     7381 tagcgtgcct acacgtgtcg taaagctgcg ctcataatag ccatttcgtt gactttgtcg
     7441 gttttctgtt cgttcatatt cttttgcttg aatatattct gttcgttgat tttccattag
     7501 ttgattaaat accgttgtta aaatattttt agaaacgtca tcctttacag aatattcaat
     7561 aatgctttga atctcttcgc ttttcagtgt aaaatgtact tgggtcatgt aaaagtcctc
     7621 ctgggtatgt ttttgtcgtt aaaaacattg taccgtaaaa ggactgttat atggcctttt
     7681 tactttta
//
LOCUS       DADVXB010000132         7339 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.136, whole genome shotgun sequence.
ACCESSION   DADVXB010000132 DADVXB010000000
VERSION     DADVXB010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.136"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(40..873)
                     /locus_tag="KB902_002299"
     CDS             complement(40..873)
                     /locus_tag="KB902_002299"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBB6809081.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(1065..1769)
                     /locus_tag="KB902_002300"
     CDS             complement(1065..1769)
                     /locus_tag="KB902_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6809082.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(1792..2418)
                     /locus_tag="KB902_002301"
     CDS             complement(1792..2418)
                     /locus_tag="KB902_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6809083.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            2744..5119
                     /locus_tag="KB902_002302"
     CDS             2744..5119
                     /locus_tag="KB902_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBB6809084.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(5143..5634)
                     /locus_tag="KB902_002303"
     CDS             complement(5143..5634)
                     /locus_tag="KB902_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBB6809085.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            5821..6741
                     /locus_tag="KB902_002304"
     CDS             5821..6741
                     /locus_tag="KB902_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6809086.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            6895..7239
                     /locus_tag="KB902_002305"
     CDS             6895..7239
                     /locus_tag="KB902_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBB6809087.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT         2397 a         1324 c         1425 g         2193 t
ORIGIN      
        1 cagaacattt ctcaaataag agaagtgttc tggttttttc tacattgcaa taaaccaata
       61 accaatcaaa atgataccaa ggataatacg ataccagcca aaagcggtaa agtcgttttt
      121 cttcaaatag cttagtaaga atttgatagc taagacggaa accacaaaag atacgaatgt
      181 tcctacaaga agaacaacag tttcttccat tttgaatgaa ttcccttcag ctaaatattt
      241 gacgatcttc aagccgcttg cgccaaacat gacaggaatc cctaagaaaa atgaaaactc
      301 tgtagcgaca aaacgcgaag caccaatcaa gatagatcct aggatcgttg cgccagaacg
      361 ggatgttccg ggaacaagtg ccaagacttg gaataaccca acaagaagag ctgcttggta
      421 cgtaaagtca ttcagagaag tccaacgagg tgttttgttt ttgttgcgtt tttcgacaat
      481 aataaaggca ataccgtaaa cgatcaaaac aatggcaact ggtaagaact tgtggaaatt
      541 tgcttctaac caatcatcca aaggcaaacc aatgatgatg gctggtatgc aagcaacgat
      601 cactttaaac caaagtgtcc acgtatcttt tttttctacc gttgatttac ttggagaaaa
      661 tgggtttaac ttgtgaaaat aaagaacgac gacagccaag atcgccccta attggataac
      721 gacattgaac atcgacataa attgtgaact ggcatccagt ttgatgaatt catctgctag
      781 gatcaaatga ccagtactac tgatgggcag ccattccgtt attccttcaa taataccgag
      841 aatcactgct ttgataatat ttgcaaaaaa cataaattcc ttccttccca attaagatac
      901 atcttatagt ataccgttat tttttgagaa acccaatctg ttttttaata ttaagaaaaa
      961 cttgagaaat aaagcagata agtacacgaa gagaaaaaag aagacaaagc cctcgttcag
     1021 actttgcctt ttatgattct ctggtaaaaa ttaaaatatc cccattatag aaacgagtcg
     1081 cgactatgtg ttttcccgtt atcgatataa gacgtatcat tgatgccgtg gatagaaaat
     1141 cgaccgtttg cataagtgac ctttgttacg ctgccattta aaagcccagc acgaacaggc
     1201 tgtttaggat cgatcagatt aagcaaaaag gcgatcgtca aaccatgaga tacgactaaa
     1261 acatttccac caccattttt ttcgcagtga tgggcgatat cttcaaatcc tgtccataca
     1321 cggtctcgca atgtttcata agtttccgcc cacccagcgg tatctaagtt gtatacagca
     1381 ttagcaattt gttcaaaaga aacttctgtg gtaaacattt catcatatgt tttaaaattc
     1441 aatacacgag ggatcacacc ccacatttcc atgtcatatc caccttcaag agacccgaaa
     1501 caccattctc taatcctttt ttcaataaaa taaggaattt cttttccctt agaatgttct
     1561 cctagaataa tacgggcagt ttcgattgca cgaccactgt cactagaata agcaaatgaa
     1621 aagtcgacat tttttaaccc gcgacctaaa taatgaatgc cttcttgtcc ttgctttgtg
     1681 aggggtgtat cacaccagcc ttgtactcgt tcaattgtat tgaacatcgt ttttccgtgt
     1741 cgtacgatat aaagtgtagt ttctgtcatt ttattctcct cctaagtcgt tttaacgatt
     1801 gaaaaaagga tttgtccttt tttcctgttc aatcgtcgtt gcatcgccat gtcctggata
     1861 gactgcaaat tcatcaggta atacaaacag ctgggtccga atactatgaa gtaattgttc
     1921 taaattccct gtatacagat cggttctacc gatacttcct ctaaacaggg cgtcgccaga
     1981 aacgacaaaa tcatcaaaaa taaagctgac gcttcctata gaatgccctg gggtagggac
     2041 gacgcgaaaa gacatgtttc ctaaagtata agttttcatt tcaaattcat attctgcagg
     2101 cgagacaata acatcagcaa tatcatcatg tctaccgagt ccagaaagat tcaaaatcgg
     2161 atcacctagc catttttgct ctagtgggct gacataaact gggatttgat aatacgcgcg
     2221 taaaggttcc actgcaccga tatgatcgta gtgagtatgg gtaagcaaaa tcgctaccgg
     2281 ctgttggttt gtttttttga tttcttgttt gattcgttcc gcatcttctc cagggtcaat
     2341 gatcaaaagt gcttcttcgt tgtagaccaa ataacagttt tcttcaatca ttcctgtttt
     2401 taatctttcg atatgcatgt gcattcctcc ttgatagcca aaacttcttt catccattag
     2461 tataacgcat tcattgctag gaaacaaaaa caggtactta tttctcttta cttatctgaa
     2521 ttatcagact atatgaaaag tatttggata ttctaaagag aaggaaagta agttttcata
     2581 gcattttaat atgtccttgt tacattagat tcatccaaaa atccaaattc tatatcctat
     2641 atccctgcct aatcagcagg gtgttttttt atgtttggaa agagagctct ttttgctaaa
     2701 ctaggttttt tcaggtaatc ttagagagaa agaggtggtg gaaatgatca aacagtcaaa
     2761 aatatctgtg cggcacttag tagaatttat tttgcgacgt ggaagtatcg acaatcgtaa
     2821 aaaaagtaac catactgcat tagaaggagc gagaatccac cgcaagctcc aaaaagatgc
     2881 gggagaaaac tatgaaaaag aagtcttttt aaaaacaaca gttcaattag atgaatatta
     2941 cctgatcgtt gaaggccgtg cagacggtat tttcaaaaga gacggtattt attatataga
     3001 tgaaatcaaa acctccgaac cacgatttga agatttagaa ccagaacaag tggaactttt
     3061 ctttcatcaa gcaagggtgt atgcctatat ctatagtcaa gaacatgatt tacaagaaat
     3121 aaatctgcaa ttgacttact tccagacggc agaagaagtg atcacgagaa aggttgaaca
     3181 tcagacaaga gagcagttag aaactttttt taaaaagctg actgaagatt ataaagaatg
     3241 gcttgttttt caagaaaact ggcgcactgt acgcaatgcc tctttgatgg ctttgaaatt
     3301 cccccatgat gagtatagga aaggtcagcg tgaactagcg gtagctgctt ataaaacgat
     3361 ccgtacgaaa cagaaattgt ttgtagaagc acctaccgga acaggaaaaa caatctctac
     3421 gttattcccc gctttgaaag ctgtagggga agaagaggga gaaaagatct tttatctaac
     3481 ggctaaaaca ataactagac aagtagctga agatgctatg acagcattaa aagatacagg
     3541 agctgaagta aaaagtgtca ctttgacggc gaaagacaag atctgctttt tagatgagac
     3601 gacctgtaat ccagatcagt gcccatatgc caatggttat tacaatcgga ttaatgaagg
     3661 tttatgggat cttttgaatc atgagaatca gatcactcgt gaagtcatcg aaacttatgc
     3721 aagaaagcat acactttgtc ctttcgaact atcattagat gtcagtatct ggtgtgacgt
     3781 aatcattggg gattacaatt atttatttga tccaactgtt tatttaagac gtttttttga
     3841 agatgaaaaa aacgaggact atctgttttt gattgacgaa gcacataatt tggtgaatcg
     3901 ttcccgagag atgtattcgg cagaactatc ttatgaaaaa acgaaacgaa gtaaggaagc
     3961 tataccaaag gaattcaaaa aacttcatcg ccgtttcaac aaactattaa aagaatttga
     4021 ttcgatccga gaaatagcaa aagaagatca ttgggattat catcatcaaa aagcaccggc
     4081 tgaatcttta gtaaaggcag gttatcaatt aagcgaaaaa attaaagaat ggctggcaga
     4141 atttcctgag cacccatcac aagaacaatt gcttccttat tattttgatt tgcttcattt
     4201 tttgaaggtc agtgaatttt atgatgatca ctacgaaaca acagtcgaaa aaacgtatcg
     4261 cgatctgata gtaaaagagt tttgtattga tccaagcttg tttcttgagc agtcgttgga
     4321 taaaggaaaa agcagtattc ttttttctgc tagtttttca ccactctctt attatcagga
     4381 aacactgggg ggacaaaaaa gtctggctta caaactgccg agtcctttcc cagaaggaaa
     4441 ccagcaagtt ttcatcgcaa attacctaga gacgacttat cgaaaaaggg aacacagtct
     4501 ggcaaaatta gtagagacga ttcatgcttt tgctgatgga aaggtcggga attatttcgt
     4561 tttctttcct tcttatcaat atttagatct tgcggtggaa gcattcagac agcaatatcc
     4621 cgacagcaat gtgctaatcc aagaaacgga catgaatgag gaagaacgcg aacgattttt
     4681 aacaaaattt caaacaaatc ccgctgaaac attgattgga ttttgcgtac ttggcgggat
     4741 tttttcagaa ggaatcgatt tgagagggga ccgattgatc ggcagtatga tcgtaggtgt
     4801 aggtttgccg cagatgaatc atgagcagga actgatcaaa tcatattatg atgagaagga
     4861 acaccttgga tttgcttacg cttatcagct tcctggaatg aacaaagtct tgcaagctgg
     4921 tggtcgagtg attcgtggca tggcggatca aggaatcgtt gtattggcag atcaacgatt
     4981 ttctagtttt tcttatcgac gtttattccc acaacattgg caaacagcaa gagaagtacg
     5041 aagtgttggg gaattggaag aaggaataca gcgtttttgg ttatcaaaag aagcagtaaa
     5101 tcaaaaaaac gaggaatgac agacgtcagc ctcgtttttt gattaacgat agttagtgaa
     5161 ttgcaactcg attggtaagt caagtttacg taataaagca atcacagctt gtagatcatc
     5221 acggttctta cctgtcactc taatctgatc ttcttggatt tgtgctttta ctttcagttt
     5281 ttcatttttg atagctgtag tgattttctt cgcgttttca cgatcgattc cgttgaccaa
     5341 atcggcagtt tgtcgagctt tgccacctag agcgtgttct gattcggaaa aatggatatt
     5401 tttgattggc acatttcttt tgatcagctt accaaataat acatctttga tctgttcgat
     5461 tttgaaatca tcatcgctca atacaactag attgctgttc tctaatttga tttctactgt
     5521 agaatccttg aagtcaaagc gattggacaa ttcttttgtt gtttgctgaa tcgcattttt
     5581 tacttcttct gtattgactt ctgatacaat gtcgaagcta gcatcttttg ccataggaac
     5641 cctcctgata tacatataaa tatttaccat acatctatct tatcatagga ttagggcaga
     5701 ttcttacctg tttgctaaaa ttcttctcat ttgagttcga agtattttat tttaatagat
     5761 aaactgttat tcttacattt ggaataccaa agtaggggag aggtgcttgt gagtaaaatt
     5821 atgactgcgt atcataaaaa tgaaagatta aagaaaatag tggttatttt gataaccgga
     5881 ttgaccgctg cggtcgcttt aaattatttt ttgattccag ccaatgtctt ttctgcaggg
     5941 atgaatggga tcgctcaaat catttcctcg cttttatatg aatggtttca tatcaagata
     6001 gacacaggaa catttatttt tcttttgaat atccctgtgt ttgtattagg gtttctcaaa
     6061 gtaggaaaac gagcaacgat ccttagtttt gtgaatgttg tatgtgtatc ggtgatgacg
     6121 atgctgcttc cagtcggaca gatcactgat aatattttga tgaatgccct agtaggcggt
     6181 gttttattag gtcttggcgt aggattatct ttaaaaatgg gctttacaac tggtgggatg
     6241 gatatcatct ctcttgtact ttcacaaaca actggaaaaa cagtcggaaa ctacatgctg
     6301 attctaaatg gtatcattgt agtcatcgca ggcttcttct ttaactggga aagtgccttg
     6361 tatacgatta tttccattta tgcaatgact caagtaattg atgccatcca cacgagtcat
     6421 caaaaagtaa cagcaatgat cgttaccgtc aagccagaag aggtaacaga agaactagca
     6481 aaacggatgg tacgtggaat gacattactg ccgtctgtcg gtggctattc aaaaaaacaa
     6541 gggaacatga tcatgatggt catcacccgc tacgaaatgt atgatcttga tcagatcgtt
     6601 catgaaatcg acgacgatgc atttatcaat attttaccaa ctcattcagt atttggccgg
     6661 tttgcaaatg aaaacgaaca aaaaatgtat cgaacaactg gcgtattgcc agaaataaaa
     6721 aatcgttcac aaaaaaaatg aggaatcagg tttattttag aataaattta atctattaca
     6781 tctaataaga acatttttat aaatttaaac gagaatctta cttctaaatt ctcatttaca
     6841 agcagctaaa aaaagagtat gataaataaa aatcgtgtta aggagtgtcg tacgatgagc
     6901 gaagcaaacc aagaacggtc tggacaagaa atagaactaa tcaaagaacg tattcttgct
     6961 gccttggaaa tggtgattga tcctgaatta ggaatcgaca tcgtcaattt aggcttgatt
     7021 tatgatatag aattcaatcc tgaaaatgga gaaacagtca ttaagatgac tctaacaact
     7081 atgggctgtc cattagcaga tattttaaca gaatctatcc atgacgcatt aaaagaagtg
     7141 ccagaagtaa cgaaagcaga agtcaaacta gtctggtatc cagcatggac gacagataag
     7201 atgagccgtt atgcacggat tgcgttgggg atacgataga aatcttggct gactagctat
     7261 gagaagcaaa taggaaaaac aaaaaagcct tttatccttt ctagaagaaa agagataaaa
     7321 ggtttctttg tttataaaa
//
LOCUS       DADVXB010000133         7289 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.137, whole genome shotgun sequence.
ACCESSION   DADVXB010000133 DADVXB010000000
VERSION     DADVXB010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.137"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            307..576
                     /gene="rpsN"
                     /locus_tag="KB902_002306"
     CDS             307..576
                     /gene="rpsN"
                     /locus_tag="KB902_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6809088.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            591..770
                     /gene="rpmF"
                     /locus_tag="KB902_002307"
     CDS             591..770
                     /gene="rpmF"
                     /locus_tag="KB902_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6809089.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            802..1179
                     /locus_tag="KB902_002308"
     CDS             802..1179
                     /locus_tag="KB902_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809090.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1200..1349
                     /gene="rpmG"
                     /locus_tag="KB902_002309"
     CDS             1200..1349
                     /gene="rpmG"
                     /locus_tag="KB902_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6809091.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1373..2356
                     /locus_tag="KB902_002310"
     CDS             1373..2356
                     /locus_tag="KB902_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6809092.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2386..2508
                     /locus_tag="KB902_002311"
     CDS             2386..2508
                     /locus_tag="KB902_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6809093.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            2526..4049
                     /locus_tag="KB902_002312"
     CDS             2526..4049
                     /locus_tag="KB902_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6809094.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4073..4312
                     /locus_tag="KB902_002313"
     CDS             4073..4312
                     /locus_tag="KB902_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809095.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4505..5140)
                     /locus_tag="KB902_002314"
     CDS             complement(4505..5140)
                     /locus_tag="KB902_002314"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6809096.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5161..5379)
                     /locus_tag="KB902_002315"
     CDS             complement(5161..5379)
                     /locus_tag="KB902_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809097.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            5505..6709
                     /locus_tag="KB902_002316"
                     /pseudo
     CDS             5505..6709
                     /locus_tag="KB902_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180763.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            6704..7111
                     /locus_tag="KB902_002317"
     CDS             6704..7111
                     /locus_tag="KB902_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6809098.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
BASE COUNT         2568 a         1085 c         1431 g         2205 t
ORIGIN      
        1 gttatagttt ctttcatatt gccgttttaa gtagaggaaa agctacttaa aacggtattt
       61 gtgtttgatt ggactaataa aagtgaattc ttatttttca gagcttaaac tgcatattct
      121 tttaaatgat ttgattatct ctatgtaccg ataaattcgt tttcaaatag ttatctattc
      181 atatgagttt tatttcatgt tatttattgt tgacaagagc aactcttgtt ggtaaagtat
      241 cagtgtcaaa acgtaacgat tacgatttga gatgtctaaa tcaaaataaa aggagtataa
      301 aggtatatgg caaaaaagtc gaaaattgct aaagcaaaga aacaaatggc gatgattgaa
      361 aagtacgcag ataaacgtca ggaattaaaa gccgcaggag atcgcaccgc tctcgctaaa
      421 ttgccaagag attcaaatcc gaatcgtctg aggcttcgtg atcagacgga tggtcgtcca
      481 agagggtata tgcgaaagtt cggtatgtcc cgtattaagt ttagagaact tgcccatcaa
      541 gggttgattc ctggagtaaa aaaagcaagt tggtaaaagg aggaaatatc atggcagtac
      601 cagcaagaaa aacatctaag gcgaagaaac ggttaagaag aactcatcaa actgtagtaa
      661 aaccagaaat ttcatttgac gaagcgaatg gtgattatag acgtagccat catgtatctt
      721 taaaagggta ctataatgga aagaaagtaa ttaaaggagc ttcaaaatag tttaatatat
      781 aacttttagg agggaatcaa aatggaaatt atttacccac ctttagttga agaaggatta
      841 aagtattatc ttgaaacgac ccagcaatcg ctagataaat gcacttttta tcgttcgatg
      901 gtagagagag gaattattac tgaaacgggt ttaccgaccc aacaggcaat tgaaaatgga
      961 ttagtcaaag attactatga ggaccaaggc ttatcatttg atgatttttt aagaatctat
     1021 ccaatttttg aagagtatga cgaggagtta tttcaatgta ttgatggtta ttgggagata
     1081 cctgttgata tgaaagaaaa tttagtttca caattggaat ctggcgagtt aacttttgaa
     1141 gatgcacaac aaattcaagc atatcttgaa gatcgataag tattgaagga ggaagattta
     1201 tgcgtcaaaa tattattttg gaatgtgtcg aaactggaga acgtctgtat ctcaccagca
     1261 aaaataaacg gaataaccct gaacggttag aattaaaaaa gtattcgcca aaattgcgca
     1321 gacgggcaat tttcaaagaa gtgaaatagc taagtggtaa aaaggtgaca aaatgggcat
     1381 accagttaca atcgtttctg ggtttttagg ggctggaaaa acaacgctaa tcaatcaagc
     1441 cttgcaagtc tcaccctacc ccagggaaga aattattata attgaaaatg agtttggtga
     1501 agttgggatt gatcacaaat tattagttca tagcgaggaa cgggtgttac aactaaataa
     1561 tggatgtatg tgttgcagtc ttcgcagtga tttattagca atattgattt ctttactgga
     1621 aacaatagaa gaacatcaac aaccaatttc acaaatcatc attgaaacta caggtatagc
     1681 agatccccaa ccaatcattc aaacactttt aacagcgcct caactaagag gaagagtata
     1741 tatcgatagt ttattgactg ttattgatag tgacagtttt gaacttattg aaagagaacc
     1801 acaagccctt aagcaacttg tcatagcaga tcgcattttt gtgtctagaa aacaaaactt
     1861 gaatttatct gcactaaaaa aattacagag agaaatcaaa agtattaacc ctttatccga
     1921 tattcgaatg ttcacacata gtgaaacgat tcaaaaaaag gatttttata atttggaaaa
     1981 attcaatcat cccttagttt ttgaaagtga ttcatcagaa aatcactata atggcaaaca
     2041 ctatcatcaa catcatcaag aacatgagtt taaatcaatt ctcttaactt cagatcaaga
     2101 cataaaaaaa gattttttat tccaattaat tgaccggctg attttaacca accaagggag
     2161 cctgtatcgt tttaaaggat tgattgcttt gcaagatcaa gattttatag ttgccataca
     2221 aggggtaaac gaacaggtta attttcaata caccactcga caaaaagacc aaaccactat
     2281 tattctaatt ggaaaaatgt tggatgaaga aaggatcaaa cagagttttg ataaattact
     2341 ggcggaaagc aaataatgat aagtattgat taggggtaat ttctaatgga gaaaacggat
     2401 atatctagtg catatcgacg acttaaaagc ccgaatatca aaactagaaa aagggcatta
     2461 aaaattatca aagaacataa acaaaataaa atgaagaaat tagcataatt aaggaaggaa
     2521 aaagaatgaa gaaaatcagt gtaggactta ttgggatagc agctctagga ttattgggag
     2581 cttgctccag cactaatgat gcaaaagtat cgaatgataa agatggaaaa ttagaaattg
     2641 taacaacatt ctatccaatg tatgatttca ccaaaaacat cgtcggcgat gaagcgaacg
     2701 tggatttaat ggttccagcg ggatcagaac ctcatgacta tgagccctca gctaaggata
     2761 tggcaaaagc tcatgatgct gatgtttttg tatatcataa cgaaaacatg gaatcatggg
     2821 taccaaaagc taaagaaagt tggaagaaag ctgggcctaa tgtagtagaa ggaacaaaag
     2881 acatgatttt attgccaggt agtgaagaag aagatcatga tcacggagaa gaagatcacc
     2941 atcatgaact agatcctcat acgtgggttt cacccaaaat ggcaattaag gaagtttcaa
     3001 atatcaagga tcagttagtt aaattgtatc cgaaaaaagc aaaagtattt gagacaaatg
     3061 ctgaaaagta tttgactaaa ctgaaacggt tggatgctga ctataccact agtcttaaag
     3121 aagcgaaaca aaaaagtttt gtgacacaac atgcagcctt tggatattta gctttggatt
     3181 atggattgat acaagttcct attgctggac taagtcctga agaagagcca tcttctggtc
     3241 gattagctga attaaaagag tatgttaaaa aaaataagat caattatatt tactttgaaa
     3301 agaatgctaa tgataaaatc gcaaaaactt tggccaatga agctgggata aaattggaag
     3361 tattgaatcc tcttgaaagt cttacaaaag aacaaatgga taatggtgaa gattatgttt
     3421 cagtaatgga agacaatcta aaagcgttag agaaaacaac tatggttgct ggtgaagagg
     3481 tagttccaga aaaagaagcg aaggatgaaa agacagttgc taatgggtac tttaaagatg
     3541 ccgatgtgaa ggatcgcgaa ttgagtgatt atacaggcga atggcaatct gtttatccgt
     3601 tgttaaaaga tggaattttg gatgaagttt tcgattacaa agcaaaactc aataaagaca
     3661 tgacagctgc cgagtacaaa gattattata ctactggcta taagacagat attgatacta
     3721 tcaacattaa agacaacacc attgattttg tagtcaacgg tgaacatcat caatacacat
     3781 acaaatatgt tggatacaaa attttgaatt atgaaaaagg aaaccgtggt gttcgtttta
     3841 attttgaaac tgatgatgca ggtgctggtc gttttaaata tattcaattt agcgatcatg
     3901 gaattgcacc aagtaaggca gagcatttcc atattttctt tggtggagaa agtcaagaaa
     3961 aactttataa tgaaatgcat aattggccta ctttctatcc agcttcatta tctgagcatg
     4021 agattgctca agaaatgatg gcccattaaa atccaatctt tggaggaaat acatggtaag
     4081 aaaagtatta ttgtctatgg attccaagaa tattgatgct tatcggcgtt atcaatttgc
     4141 aaagcaaatg agattaaatg ggagtacatt agctgatatt gctgcaactt tacatgttag
     4201 tattgacaca gttcatagag tattaaaacg ggatcctgat tgttgtttta tcaaggtcaa
     4261 tactggaaga agtagacgtt tagcaaaacg gcataatagc ttggccaatt aattgataat
     4321 accagagtag atcatttttc ccttatttgg atttgatctg ctttttatta tttcttgaat
     4381 tgtcaaatca agcgcaacac tttatcaaag aagacttcat aaggtgttct ccaatctaaa
     4441 cactttctag gtctgttatt cagtttttca atcatctgat ttatcgttga gttatctacc
     4501 gtagctatct ctttcgattt tggcaagtat tctcgaatga gtctattcgt attttaattt
     4561 gttcattgtt gccaagggca tgaggatctg gaaaataaaa gggcatatta ttcaatactt
     4621 ctgtaactgc gaaatgattg gagaattctt ttcctctatc tggagtgatc gttttgaccg
     4681 cctcatttgg aatactgctt aaaagttcaa tcattttctc gctcacataa gcggctttct
     4741 ttctggggac cttctttcct gctaaaagga agcatgattt tctgtctgtc aaagtcacta
     4801 aacaagtacc actagttttg ccagctacaa tatcggcttt ccaatgacca aaatcacttc
     4861 tatcatctgc ggattttgga tggccatgga tcgaatgagt aaggcaaatc ttcccacgag
     4921 actcgacatg attttttgta tgtcttgttt ttcctcgatg gtgcaatgaa cggatcaggc
     4981 ctttattgcc gtgtgagagg ggttctgtat cgaaaagatc attgcaaatt gcacggtaga
     5041 tcgtgataaa actaattgaa aagtccatat gttcatgctt caaacgattc gagattttct
     5101 ctggcgacca ctgaaaatcg acaaataaat gacgaacaat tgaccaaact cacggatcat
     5161 ttagaatgtg ataacgtccg catttttttc ttcgataagc ataatttttt tccgctttgg
     5221 aaggtgatta gtttttttct tgtttcttct cagttcatgt aaaatagtaa acgggctatg
     5281 ctgaatgtcg ttgccaatta tactaataga aaatccttct tcgtgaagca gaaagattct
     5341 ttctcgtttg agtatagtaa gatgacaata ctggctcata attattttcc ttctaggagt
     5401 gttctcgaca aacttatact agttggatat cgattatgac tcatttttat gtgttgcact
     5461 taaagtgtaa attcaaggta tagaaagagg ttccctatga aaaaatacct attacaatct
     5521 taactggcta tcttggttca ggaaaaacga tacttctaaa tcatattctg tacggtgatc
     5581 acggaaagga aattgctgtc attgtaaatg acatagggga agtaaatgtt gatggggtat
     5641 tagtcgacaa gaaaggtttt aaaagaactg gagaaaaact tgtttcgatg ccgaatggat
     5701 gcatttgttg tacattacgc gaagatttga ttgttgaact agatcaatta gtgcaatttt
     5761 ctgacttgaa tcaaattgtt attgaagctt caggaatcag caaaccaatt ccaattattc
     5821 aagcaattat attagctaaa aaccctttag acattgattt gacccaacga ttagagattg
     5881 gtgccattat tatagtagtg gatgtaaaac gtttttggga taatttcgaa acgggtgaaa
     5941 agattcagga aagaaaagct gaaggtaatg tagttgaaga agaacaggat attcgtggct
     6001 tgttaattga tcaattcgag tgttgtaaca tattactttt aaataatagt gacttagtgt
     6061 caaccaagac gatttacaaa attaacggtc taattgctaa gttacagtcc aatgccaaaa
     6121 taattaggac aattaaaggt gaagtagact tatcgaaaat tctaaataca aatcttttta
     6181 atatagatga gacttcctat tcaatgggct ggttcaaaga gttagagctt ggctatcaaa
     6241 atcatattcc tgaaacagaa gaatatggta tctcaagttt tatctatcga aatcggttac
     6301 tccttgacgc acaaaaattt gcccatctta cggataaaaa ttttcctggc aatattacaa
     6361 gagcaaaagg gtttctttgg tttgcccaac atagtgattt ttcgacgatc tttgaaacat
     6421 cgggtagcca taaaagtatt gaatcattaa attattgggt agctagttta cctaaaattg
     6481 agtgtcaaat gattatacaa aaaaacccga attgaaggaa gcctggcatc cgttgtttgg
     6541 tgaacgcatt aataaactag tttttattgg tatgaagatg gatcaacaat gtattaagga
     6601 acaacttgag ggttgtttaa ctgattctct taatgcagat aatttccgaa aaatttcacc
     6661 atttccatgg aaaaattcta atatgtttag ccagatatcg ttaatgaaat ttttaagaaa
     6721 agctggtgtc aagataggcg atgtcataat tattggcatt ttgattattc cctcttttat
     6781 tcccttattt gtattctcta tagaaaagga gaatgaaaca actgaagatg ctatcaaata
     6841 tgccatcgtt caaattgatg gcaaggaaat ggatcgcttc gatttggata agatcaatca
     6901 taaactcgtg aattatcatc ctgcgaaggg acaatataat attgttgaga ttaaagatgg
     6961 aagaattcga gttaaagaag ataatagtcc tgatcaaatc gcggttagaa ctggatggat
     7021 ctcaaaaccc ggtcaaacga gtatttgttt accccataag ttagttatta gtattgagaa
     7081 aaaagaaagc aaagattact acatttacta atctggaaat agatgaggag gtttttaata
     7141 agaaaaagat attattatta ataatagcag gggctttatt aagtgtgtta agcgcttgtg
     7201 gacaagaaaa agaagcggtg acaacaggca caagtatctt taacgggacc tgcaatggtt
     7261 tagttaacag tcggttagat tacttattt
//
LOCUS       DADVXB010000134         7248 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.138, whole genome shotgun sequence.
ACCESSION   DADVXB010000134 DADVXB010000000
VERSION     DADVXB010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.138"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            718..2595
                     /gene="ltrA"
                     /locus_tag="KB902_002318"
     CDS             718..2595
                     /gene="ltrA"
                     /locus_tag="KB902_002318"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6809099.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            2726..3103
                     /locus_tag="KB902_002319"
                     /pseudo
     CDS             2726..3103
                     /locus_tag="KB902_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            3103..4302
                     /locus_tag="KB902_002320"
     CDS             3103..4302
                     /locus_tag="KB902_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6809100.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            4318..4962
                     /locus_tag="KB902_002321"
     CDS             4318..4962
                     /locus_tag="KB902_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809101.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNLVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            4973..5779
                     /locus_tag="KB902_002322"
     CDS             4973..5779
                     /locus_tag="KB902_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809102.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEISTNAFVNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFAVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKENI"
     gene            5802..6032
                     /locus_tag="KB902_002323"
     CDS             5802..6032
                     /locus_tag="KB902_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809103.1"
                     /translation="MKRANLVGKDTFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKFRSFEALYLAAKKYFTAERK"
     gene            6296..7168
                     /locus_tag="KB902_002324"
     CDS             6296..7168
                     /locus_tag="KB902_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809104.1"
                     /translation="MKSTDWIKHTWLPLKRNSKRKEFWILQLWPLGKLCSYLARFILD
                     LIIYSIVVFGTAYYLLNDPNRIAASDIFTVLMTLIFVMLLSIFTQIVMQFTRQKLTAG
                     KLFKSLFDLIIVNAILATLIKQIEQFGRTTKGVKEFLMTFVHFVNGHMYLFEVGIILF
                     LVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYYVDFGRYDELINTDIVHTSIHEATVKG
                     IRTTLKDGQETKAIDRRKEVYNFYEVEANLRYGIGKLSLNGRNIPQNKPYIGWKSDAL
                     EVTKKLPMEEEEIQ"
BASE COUNT         2674 a         1108 c         1550 g         1916 t
ORIGIN      
        1 gtgaaaagct gtgggttgca agtagtctaa aaactattgt aataactctt ataacgagaa
       61 gtcaaatgag tgggtaacgc cacaaagggc ttccactgat actccgacat gcaacaagta
      121 gtttatgcag accaacgttg tgtgaagctc ggtgaagtcg gctgaaggat accgtaaggt
      181 aaaagaaata gtgaatacca cgaaagttct ttagaggtaa agggtgtatc cgataagtcg
      241 ggtgtccaaa aaaacttaat atggtgagta tgtacaaacg tactgacgaa ctagcgaatg
      301 tactgtccga aaggcatagc tcctagaaat gggagagaca gtgagcaaaa aatcactcat
      361 tgtgctaact tgtggttgag taaaagtcgt tgttatgaaa gaccatgctg cgttacaggc
      421 gtaggagaag ttagggggca aaagctagca tctaagttaa ggcatgtgga tagatataag
      481 ggaacagggg aagccatcaa catggagagt gcatactcga tgaagtggta gtaagaaata
      541 tgtgaatgac aaataactta ctttagtgat ggtgaaagta gagtcacgac tgatgaaggt
      601 tctgtaatgg aactggagga acaggctcga ttcgtctgta aaagtcatga aacccgttca
      661 accatgggat tctcgtatga ctaaaaaggt cacgagccaa ttggagcgtg ataaaccatg
      721 acaaaagaaa caagtccaaa agataggaag ttgcggcatg cagaatatta tggcatgacg
      781 gaaatcttcg ataagatata ctccaaaagt ttgaagggag ataatttcaa gaatctaatg
      841 cagattatca tttctgataa caacattgtc ctagcatatc gtaatatcaa gagaaatcac
      901 ggtagtgtga caagaggaga agatggagta acgattaaag atattgaaaa tctcaaccgt
      961 aatgaattcg tagaaattgt taggaagcga ttcgcacatt ataaccctcg gaaagtaagg
     1021 cgtgtagaaa ttcctaaata taatggtaaa ttaagaccgt tgggtattcc atcaatatgg
     1081 gatagaatcg cgcagcaatg catcttacaa gtattagaac caatatgtga agcaaaattc
     1141 aataatcaca gctatggttt ccgcccaaat agatcagcag aacacgcaat agcagattgt
     1201 atggcccgaa tgaatcaaag tcacatggaa tatgtggtag atgtagatat caaaggtttc
     1261 ttcgacgaag tcaatcatac taaactcatg agacaaatct ggtctatggg tatacgagac
     1321 aaacagcttc tcttaatcat taggaaaatg ttaagagcac ccgtagtact tccaaatggg
     1381 aagttgatat acccaacaaa aggaacacca caaggcggaa tacttagccc attacttgcg
     1441 aacatcaatc tcaacgaatt tgactggtgg atagcaaatc agtgggagga aaaagatgcc
     1501 aaagagctaa aacatcattt taggaaaaat ggagcttggg ataaaggtaa tatctatcac
     1561 aagctcagaa agagtacaac tctaaaagaa atatacctag tgagatacgc agatgatttt
     1621 aaaattttct gtagaaatta taatgaagcg aaaaaagttt tctatgcaac taaaatgtgg
     1681 ttacaggagc gtctaaagtt accaatatct gaagaaaagt caaaaatcac aaatctttca
     1741 aaagaagaaa gtgaattttt aggctttacg atgaaattag tgaccaaagg taacaaaaag
     1801 gttgttaata cgcatatagg tacaaaagca caaagcatga ttaaagtgaa actaaaaaaa
     1861 caaatcaaac gaattcaaaa aagtcctaat agcaaagata cctttatcta tattggagtc
     1921 tataacagta tggttattgg gattcataat tacttcaaaa ttgcgactca ttgtagtgta
     1981 gcaatgcgaa aaattgcaag agaactcaga ccaagttttg aaatacgact acgagaacaa
     2041 ggaatctcaa aagaaggaca atacggaaag tacgaaggat acaagcctta cctacggtca
     2101 ggacaaatac gatatataag agggtttcca atattaccag tagggtatat tcaacacaga
     2161 catccgatgt gtaaaaaaag aaatattaat aaatacaccg aagaaggtag ggaagccatt
     2221 cataagaagc aacaaaccgt agaagaatgg aagatatcgt ggttgtgtag caatccagtg
     2281 cttagtaaga gagcaacgat tgaatttgcg gacaatcgaa tttcaaaatt catcgctcaa
     2341 aagggaagat gtgcagtaac aggtgaggag cttatcttat ctgaaatgca ttgtcatcat
     2401 attatccctt atcatgaaag caaaagtgat agctatgaaa acctagtgat tgttactgag
     2461 gaggttcatc gggtaataca cgctacacaa agtgaaacga ttgaggaact tctaaaatat
     2521 ctaaaattaa atccaaaaca aaaagaaaaa ctcaatgagt tgagattaaa agttggtaac
     2581 gaagaaatat cttaataaat atttgtagga cgggaaaaca gaatgtcttt tatagacgag
     2641 ggaacgccgt atgcggtgaa agtcgcacgt acggtgtgga ctggaggaaa agacggagat
     2701 aatatcaaac tcttacctat cagtatcgat taatccagat ttcattgaaa cggtaaatta
     2761 tgtcacaaac ttccaacgag aaatgcgtaa agtagaagca atgactgttt tagctacaca
     2821 atccccacaa gaaatggtgc cagaaaatat gtcttctgat aacttctcga aactgaagaa
     2881 agtctttgaa ttttcttcta cgaagatctt tatgcgtatg gatgaatcta ttttacgtca
     2941 tatagaagga ttagttggta aatcaatgac gaactcagaa ttagaatcca ttcctcaaca
     3001 aaatcaagga gacgctgtga tcaattttgg ctcaaaagaa accattcgtg ttcattttag
     3061 tccgaacaaa cgtcaattaa aattgtttga tggaggaaaa taatggaaaa ccaaaatgaa
     3121 agtttaatca aacagtatgt taagcgtcgt gcaaagcggc gcttattttt gtgggtgttt
     3181 ggtacttctg caggtttgat tactatattg atcactgtgt ttgtgaccct ttttctaata
     3241 cttgcggcag gttctattga taattctgat tcaagtagtg gtggcgaagc ttttacagga
     3301 gaatattcgg aaggcttacc catttataaa gaaatcaaag gaagaggccc tttttctgat
     3361 gagattgcgc aatatgctgt aggtgcagca gtgaagtata aattattacc aagtgtgatc
     3421 ctttcgcaat acggttatga atcagcgttt ggtacgtcgg cgtccgcaag aaatgatctc
     3481 aattattttg ggattacgtg gtttgatggg tgtctgtttc ctaaaggaac tgcgcgtgga
     3541 attggtggca ttgaaggtgg ctggtacatg aagtttccca actcaaaagc tgccttctcc
     3601 tattacggct ttatggtagc cacacaatca aattttaatg cttgtgtcgg aaataaaagc
     3661 cctggcgcaa gcttattgat cttaggacga ggagggtatg ccgccgcagg aattactgaa
     3721 gacagtgcct attataaaaa ttgtatgtct attattaata caaataaatt gatggagtac
     3781 gatgagtttg cgattaaaca ctggagagaa ggcggcggaa ctggtggtac gattacagga
     3841 agctggggca atccattccc aggaagtagc ttagataaaa attcgttcag tggaggacaa
     3901 ctttttggga aaaatccagg aggagaattc cgacctaacg ggttccatga tggactagac
     3961 tttggttcag tcgatcatcc aggaagtgag attcatgcgg ttcatggcgg aaaagtcgtg
     4021 tacgttggca atcctggtat ttcaggtttg ggtgcgtgtg tgatcgtgat taattacgat
     4081 ggcttgaata tggtgtatca agaatttgca aatagtacag gaaattctcg agtgaaagta
     4141 ggcgatcaag tgaaagttgg tcaagtaatt gggatacgag atacagcaca cttgcattta
     4201 ggatttactc gaatggattg gcgtcaagca caaggacatg cattcattga tgatggtaca
     4261 tggatcgatc cgttaccatt tttgaatagc agcaaaaaat agatcaggag aaaaaatatg
     4321 gaaaataaaa ccttaaaaat cgtcttaaca gctgcaatta gcgttagttt aatcggcaat
     4381 atcgcgttgt tttggcagct gaaagaagaa caagagacaa atacctttaa aattgaagaa
     4441 gtggctaaaa acgcgtctga gaagctcaaa aaaaattcct ctgaggcaca ggcgaagatc
     4501 gacaagttaa atcaaaccat caatgagaaa aaccaagaaa tcgatcagct gaagcaacaa
     4561 gatggcacaa aagcaaaaga ggaagtaact gaagcacaaa gaaagacggc agaagagttc
     4621 ggtcaattgg ccattgataa atcattaagc agaaatgaat taacggaaaa actaaaagat
     4681 gtcgcaaccc aagaagtgat cgacaaatta agtcctgcag acgatgatca ccaacatgat
     4741 gattacggaa gttactcctt tacattaggt gacgtgcaaa cttacgctca aacaagcagt
     4801 gtaaaagagg aacaaaatct tgtcgtattt gttgattata caatcggcaa tcctcaattc
     4861 aaagatgtca aaccgcaaaa aataaaaggt ggattaactg tcactgaaaa acaagtagat
     4921 ggtcaatgga aagtcacaga ctttagttat ttcactcgtt aggaggaaga aaatgagtaa
     4981 gaaaaaagga gcaagacaac gtttcaaaaa acgaaaaagt tatcttagat ggctggggat
     5041 ctttatgatt ctcggctttt tgattcttgc tagtccaatt tatacgcata agaaggtaga
     5101 cataccagat gagataagca cgaacgcatt tgtaaacacg aaggaactga cgatggtttc
     5161 aaaagaaaaa ggagcgaacc agcaattagt ttttgaattt gcaatcgacg atgaagatca
     5221 aagcttatta aaagaactgg ctaatcttaa ttatcgcgta gaagtaaaga cagctaaagg
     5281 ggattatcaa gcaataaaag ccaaagtgat caaagtgtct gatgattatt ttgcagtgaa
     5341 gctatctcat gtaccagaag aatatattgc catgcgttta accattattc ctgaaaaaat
     5401 tgatccaaaa gtggatatgc aagaaccgca agatctgatt tattacgttc acgaagataa
     5461 ggttaaagat caagtgaaag atgaagatta tgaacaacat gcgatcaatt acaaagtgaa
     5521 aggatacaaa aaagaacaaa aagcagcaca aaaacagatt gaatccttcc aagcaaccat
     5581 tgatttgaat gaagaattag tgaagaaact aaaagatcaa ttgccttatc aagttgcaga
     5641 cgatcaggaa aatactgaaa ataagattaa tagttaccag caagaaattg aaacatcgaa
     5701 aacgcaaatg aaagatcaag aagagatcat tcaaaaactt caagaaaaaa ttgatcgtat
     5761 gacaaaagaa aatatttaga agaataggtg gagtaaaaga aatgaagcga gcgaacttgg
     5821 tcggcaaaga tactttcgct gagcagaaag tattgattaa agcctatctc aaagttgtaa
     5881 aagctaaaga aatatgtcaa gaagtgaatt tatctaacac aacaatatct gagttgaaga
     5941 atggtagaaa gagtttagat accttaaaat tcagatcatt tgaagctttg tatttagctg
     6001 ctaaaaaata ttttacggct gaaagaaaat aaaaacagga ggattttatg tgaaaaaagt
     6061 gtatcaaaaa tgtttatgga tcagctatat caccgtaggt atcgttggct tcttttttat
     6121 tgtagccgtg accttgggaa cgatttttct atggtttact aatgaagatt tattattgaa
     6181 gggactcatg agtgtaatct catgcgtcct attgattttg ttggggacag aaatcaacaa
     6241 acttctgcct tctcgttggc aagaaaagaa gaaagaaatg agagaagaaa ttgaaataaa
     6301 atcgaccgac tggatcaaac acacttggct tcctttgaaa agaaatagca aacgtaaaga
     6361 attttggatt ctacaattat ggccattagg taaactttgt agctatttgg ctcgttttat
     6421 acttgattta atcatttact cgattgtagt atttggaacg gcttattact tattaaatga
     6481 tcccaatagg attgcagcat cagacatttt tacagtgcta atgacgttga tttttgtcat
     6541 gctattgtct atttttactc aaatagtcat gcaatttacc aggcaaaaat taacagcagg
     6601 aaaacttttc aaaagtctat tcgatttaat tattgtaaat gcaattctag caactttaat
     6661 aaaacaaatc gaacaatttg gaagaacaac aaaaggagtg aaggaatttt taatgacgtt
     6721 tgttcacttt gtaaatgggc acatgtattt gtttgaagtg ggtattattc tctttttagt
     6781 cgggtatgta tccacgaaac ttattaaacg ttcaattgaa aaagaaattg agattgactt
     6841 gattccgaca cttcttggtt atgagtacta tgttgatttt ggaagatatg acgaattgat
     6901 caatacagat attgttcaca cgagtatcca tgaagctacc gttaagggca tcagaactac
     6961 gttaaaagat ggccaggaga cgaaagcaat cgaccgaaga aaagaggtct acaattttta
     7021 tgaagtcgaa gcaaatctaa gatatggcat tggaaaattg tcgttaaatg gaagaaatat
     7081 tccacaaaac aaaccataca ttggctggaa aagtgatgct ttagaagtaa ctaaaaagct
     7141 tcctatggaa gaagaggaga ttcaatgagt ctagtcaatt tgaatcattt gtttgaagat
     7201 atcagtaatc atttccaaca gttctcaata agagtttata ttattcat
//
LOCUS       DADVXB010000135         6891 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.139, whole genome shotgun sequence.
ACCESSION   DADVXB010000135 DADVXB010000000
VERSION     DADVXB010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.139"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..182)
                     /locus_tag="KB902_002325"
     CDS             complement(<1..182)
                     /locus_tag="KB902_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6809105.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="KB902_002326"
     CDS             517..951
                     /locus_tag="KB902_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6809106.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="KB902_002327"
     CDS             974..1294
                     /locus_tag="KB902_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809107.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="KB902_002328"
     CDS             1435..1626
                     /locus_tag="KB902_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809108.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="KB902_002329"
     CDS             complement(1697..1954)
                     /locus_tag="KB902_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBB6809109.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="KB902_002330"
     CDS             2112..2375
                     /locus_tag="KB902_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809110.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="KB902_002331"
     CDS             2399..2587
                     /locus_tag="KB902_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809111.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="KB902_002332"
     CDS             complement(2670..2855)
                     /locus_tag="KB902_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809112.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="KB902_002333"
     CDS             3070..3441
                     /locus_tag="KB902_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6809113.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="KB902_002334"
     tRNA            complement(3591..3663)
                     /locus_tag="KB902_002334"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="KB902_002335"
     CDS             complement(3709..4137)
                     /locus_tag="KB902_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809114.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="KB902_002336"
     CDS             complement(4197..4955)
                     /locus_tag="KB902_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBB6809115.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="KB902_002337"
     CDS             5250..5447
                     /locus_tag="KB902_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809116.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="KB902_002338"
     CDS             5553..6035
                     /locus_tag="KB902_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809117.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="KB902_002339"
     CDS             complement(6093..6689)
                     /locus_tag="KB902_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6809118.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT         2332 a         1060 c         1354 g         2145 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc cccagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agttatcgct ttcattgttg tgttttagga atttttgctt a
//
LOCUS       DADVXB010000136         6839 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.140, whole genome shotgun sequence.
ACCESSION   DADVXB010000136 DADVXB010000000
VERSION     DADVXB010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.140"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(545..1723)
                     /locus_tag="KB902_002340"
     CDS             complement(545..1723)
                     /locus_tag="KB902_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HBB6809119.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDCIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAV
                     YQASSKEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIE
                     SFKKQIKKYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            complement(2798..3616)
                     /locus_tag="KB902_002341"
     CDS             complement(2798..3616)
                     /locus_tag="KB902_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6809120.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3777..4466
                     /locus_tag="KB902_002342"
     CDS             3777..4466
                     /locus_tag="KB902_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6809121.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4480..5982
                     /locus_tag="KB902_002343"
     CDS             4480..5982
                     /locus_tag="KB902_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6809122.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5995..6471
                     /locus_tag="KB902_002344"
     CDS             5995..6471
                     /locus_tag="KB902_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6809123.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKYGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6568..6678)
                     /locus_tag="KB902_002345"
                     /pseudo
     CDS             complement(6568..6678)
                     /locus_tag="KB902_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2319 a         1014 c         1214 g         2292 t
ORIGIN      
        1 atcacccacc tatagaggat gggcgacttc tgcctaattt atgttaaatt tagctaaaga
       61 tttagcatca aattcatatt cagtgaattt gatttggaca ttgactgtag gtcctaagta
      121 agattaggag aagactattg ttaaaacata tggattaaca aaatatgata cagatagtag
      181 caagaatcaa actagtcaaa tgtatcgttt atataatcct catagtgggg aacatttata
      241 tactttaaat caaagtgaaa agaattcttt acctaaatat ggttggaagt atgaaggtgt
      301 ctcttggcta gctcctaatc agggtactgc actttatcgt ttgtataatc catatagtga
      361 agatcacctg tataattcta attggggaga aattaataat cttactagaa taggctggag
      421 gtactagggt ataagttttt attctggttg ccctaaaaat attttaagat tatttaatct
      481 gtatgagaaa atgggagcgt caataatttt gtgtaaataa cacgtccttc tgcaaaataa
      541 tgggttactc agtaaacatt gaagctaatg tatccgtcac ttgttggaag cctttatggc
      601 ttctatttaa gaatttttga ttgtatgtat caaagatgga tactaggaaa cgctctagtg
      661 attcttcatt ttgaaactgc tcttttctgc ggctgtattt cttgatttgt ttcttgaaag
      721 attcgattaa attagttgag taaatgcttc ggcggatacc aggcggaaac tcataaaaag
      781 tcaataaatc ttgatttttt atcagtgact gcgtcacttt aggataagtt ttctgccact
      841 tctcaatcat actccctaaa aaggtatttg cctcttcctt tgagctagct tgataaacag
      901 ccttaaaatc atcacagatt tcttttcgat ctttgacacg tactttatga gcaatattac
      961 gggaaacgtg aacacagcaa tgttggtatt tagctttagg ataaatctgg tgaatcgtat
     1021 ctttcatgcc ttttaagcca tcggtaataa acagtaagac atcatgaacc cctctggagt
     1081 aaatgtcctg taacaactca ttccaaacgt aggtcgattc agtcggagca atcgcataac
     1141 ttagtacttc tttagtgccg tcttctcgta taccaatggc aatatagatt gcttctttgg
     1201 agacggtttg ccgttttaaa ggaatataag tagcatccat gaaaatagcg acatacttat
     1261 catttagagt tctaacttta aatgcattta cttcttcagt cagcacttta gtcatgttgg
     1321 acatggtttg gggcgtgtag tgatgcccat acattttctc aatcaagtct gcgatttccg
     1381 acatggtaat accttttcgg aagaggtgaa tgacggtctc ctctaaggta tcattcgtcc
     1441 gtctataagc aggaacagtc tgttgcttga actcgccgtt gcggtcgcgc ggaatctgga
     1501 gatgaagttc cccgtactcg gtcttgaccg tacggtcata ggatccgtta cgagaattac
     1561 ccgtgttaaa accaatgcaa tcgtactttt cgtaatcgag gaaagccgtt aactccgttt
     1621 tgagaagcgt attgacagct ttttccaaat ggacacggaa taattcattc aaatcgcctt
     1681 tgttcgctag agtctttaga atttctgtag taaaatcgtt catatggaag tcctcttttc
     1741 tgtgaatgtg ttgtggtaac tctattctac agaagggact tccttttttc tatttacaca
     1801 aaatatttta cactctcact catttacacg ttatttaata agagaccacg gttaaataaa
     1861 aatagattat ataaattata taataagaag gaattaagag acatttctaa tttattccga
     1921 aaagtgaaaa caaaaaataa atttctaaaa aaatataaaa aacatatcaa attgatcgat
     1981 gaaaatctaa aaacagattg aaaatctttt catgcaaaag atatgaagaa agctgttgat
     2041 aagggagact atttctctaa attagccaaa gacaataaag taaaagaaga tagcgaaaaa
     2101 cggaaaagtg aagtttgatt caactaatac aacgattctg gtgacagtca aagaagcatc
     2161 ttttaagttg aaagacggcc aaatttctga tgtgatcact tctaccaatg attcaactta
     2221 tgatccataa atactatgta atcaaaaatg gtaaaaaatt agaataaagg caacggaatg
     2281 gataaatact aaaaacaatt gaaagaaatt actactgaaa cgaaattgag caacaatgaa
     2341 tttcaaaata aagtagtcga taaaatattg aaagatgcta atgtaaaaat taaagacaaa
     2401 aattttgaaa attttttgag tatatttact tcagatggta aggcaacaaa ataaaataca
     2461 ataggcagat gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat
     2521 caagaggatc ataaactttt aagagaggat gatccattac ttcatccata ctcgataaac
     2581 tagtgataat gagctacacg tttttctttc aagttgatca atagcttcca cgataaaaat
     2641 atttttagat aaaatcaaga accgtaggaa ctacggggat atttggtcaa taagatccac
     2701 cgctattagt aaaaaataag ctatcaagta tgctctcatc ccaagaattg cctacttcaa
     2761 tcgttaaaaa ccgttaggtt tagctaagtg gggtagttca ctcaatactt ttatcaataa
     2821 tagagcgcaa aactttttct cttaattcaa ctgaatcaat attattgttt tgttcataac
     2881 catgaactaa tagatcacaa atataaagtt gtgatatttt tccagctaaa gatccaccat
     2941 taagaaattc ttcaatggct gtttgtaaaa ctaagtctgc agactttcct ataggtgaat
     3001 gaatatagtt agttatagca ataatttttg cgccattttt tttagctatt ttcaatgaat
     3061 cataagtatc tttcgttttc ccagataaag aaaaaatgat tactaaatca ttaactgtta
     3121 ataaagaagc gacttgagct tgaaaatgag ggtctagtac agcttttgct tgaactccaa
     3181 cgcgaagaaa catattttct aaatcaagac tagtatttcc actagatccc actccaaata
     3241 tatatatgtt ttttgattga gtgatcattt taatggcttc attcaatttt tcttcgtcta
     3301 aaagcctaat agtggaatag agagcttctg ttaaactatt agcaatttca tcatagtact
     3361 ttacactagt cggatgttct tttttttgac taaagtcttc ctttgcaatt tcaattttta
     3421 aatcagaaaa accagaaaaa ccaatttttt gacaaaaacg aataatagta gcatcgccaa
     3481 cttttgtgtt tttcttaata tcactcatcg tactataaat aatagttttc ccagaattta
     3541 aaataaaatc agcgactttt ttttcagact tcgttaaaaa tggataattt tctttaatta
     3601 aatagatata actcatacaa actcctctac aatttcaact tttctccatt atactccaaa
     3661 ataataaaaa aaactcctaa atactccatt tttatcttta cttttatgaa agcggatgct
     3721 atattgtttt tggagttatt atccaaaaat aataaaaaat tggagtgttt aggataatgg
     3781 ataaaaagag gtttttagat cttatttcaa aaggtttgat tgtttcctgt caagcattac
     3841 ctggtgaacc attttacaaa gaggaagaaa gtttaatgcc ttattttgct ttggctgctc
     3901 aaagggctgg agcagttggt atacgtgcaa attctgttcg agatattatt gaaattagaa
     3961 agtgtgtatc attaccaatg attggaatta ttaaaagaga ttatccacca gaatctccat
     4021 tcattactgc cactatgaga gaagtagatg aattagtaga aaccggtgtt gaggtaatcg
     4081 ctcttgattg cactcttaga aatcgacatg atggactatc tataaattct tttattacta
     4141 aaataaaaga aaaatatcct catcagttat ttatggcaga tatttctaca tttgaagaag
     4201 gcaaaaatgc atataaagca ggaatagatt ttgtaggaac tactttaagt ggatatactg
     4261 aggaaagtaa aaaacaagat gggccagata tagatttgat taaaaaattg gtagaagaag
     4321 ggatttgtgt aattgctgag ggaaggattc atactccaga acaagcaaaa gagataaaaa
     4381 aaataggagt tgcaggtatt gttgtgggtg gtgctattac tcgaccacag gaaattgcat
     4441 caagatttgt taaagcatta agttaggggg agaaataaaa tgtttaaaaa attttcacaa
     4501 ttaggacgcg ctttcatgtt accaattgct atattaccag tagccggatt actattggga
     4561 ctgggaggag cgttaacaaa tgagagtgct ataaatgctt atccattttt agatcaaccg
     4621 tggttgcata caattttaag tattatgagt tatgctggaa atgcagtttt tgcaaaccta
     4681 gcactaattt ttgcaattgg tattgctgta ggacttgcaa atggagataa aggaacagct
     4741 ggtttagctg gtggagtagc ttatttagta tatactgcaa ctattagtgg gtttcttgaa
     4801 cttttttcag caaaagatgc aacactagat acaggtgtag tgggatcaat tgttgttggt
     4861 ggtactgttg catttttaca caatcgttat agaaaaattg aattaccaca attcttaggt
     4921 ttttttggag gatcaagatt tattccgatt gtttctagtt tagctgcaat cattattggt
     4981 tctttctttt atttaatttg gccaccaatt caaaatggtt tagtagttgc tggtgaacaa
     5041 attgcccaaa tgggtagttt aggaactttt ttatatggtt ttttattacg tttaacaggt
     5101 gctgttggac tacaccacac catttaccct ttgttctggt atacatcttt aggtggtacc
     5161 gaaactgtag ctggatcaac aattgctgga gcccaaaata ttttctttgc ccaactagct
     5221 gatccaaacc acactggtct gtttacttat ggtactagat tttttgcagg aagatttgca
     5281 acaatgatgt ttgggttacc agcagcatgt tatgcaatgt atcgtgcaat tcctaagaaa
     5341 aatcgtaaaa agaatggtgg gctttatttt agcggggccc ttacatcatt tttaactgga
     5401 attactgaac cagttgaata tatgttttta tttgttgctc cttggcttta tgtgattcat
     5461 gcattcttag atggattatc tttttatttt gctgatatct taaatattcg tgtagggaat
     5521 tccttttcag gtggtttgat cgacttttta ttattcggtg tacttcaagg gaatgacaaa
     5581 actaattggt taaaattaat tccttttggt attgcatggg catttatata tttctttgtt
     5641 tttacattct ttatcaaaaa atttaaggta gctattcctg gaatggaaga agaatcagaa
     5701 gttcattctg aaaaagtaat aaacaaaaat acatcattac atgaagagtc tcttatcatt
     5761 attgaagctc ttggtggaaa agaaaatatt gagtctgttg aagcttgtgc aactcgtttg
     5821 cgtgttgctg ttacaaatgg ggagattatt caaaaacaaa caataaaaga cactggtgca
     5881 actgctgtct tcgaagtgaa gggtggcatc caagctgttt ttggagggaa agctgactta
     5941 ttaagtcaag aaatcaatca aatattagga aaagataatt aggaggtttt taatatgttt
     6001 gaaattttca aaaagaaaaa acaagaaact ttttatgcac cttgttccgg aaaaatcatt
     6061 tccatcacag aagtaaatga tcctgtcttt tcacaaaaat tactaggtga tggttttgcc
     6121 gtcatacctg atggttcaaa aatttatgct ccattggctg gtcgagtaac aaatatattt
     6181 cctactaaac atgctattaa tataaaaagc aactcaggca ttgattattt gattcatatt
     6241 ggaattgata cagttgaatt acaaggagag cctttttcga tttgtgttca agaaaatgat
     6301 gaggttactc ctgaaacctc gttggttgat gtggattttg acaaaataat aaaatatggt
     6361 aaagatactt ctgttatagt tgtttttccg gagaaaaatc agttcaatga tttaataata
     6421 gataatggtc gaattgctca tgggaattca tgtggaaaaa tcacttttta aaaaagtgta
     6481 tataaaaagc tataaaataa gctaaatagg atatttgtca aatgaagttg gtgaacagaa
     6541 agaactgttt tctttctgtt cattttttta ttttattagt aatgattccc catgccaaat
     6601 catgatccgt aatttaaagt tataaaagct tcgaaatcca ttggcatttc gttggaatac
     6661 cttgatatga ttattcaaat ataaaatata gagagaagag agagagggaa gatatttata
     6721 aagggcaaag ttatgtttac tcaacttagg aaatagaaat agatcaattt atattctctt
     6781 gtcaatcgaa tatgaacctt agcactatat accaaatata gtaaaatgct gaaagatgt
//
LOCUS       DADVXB010000137         6786 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.142, whole genome shotgun sequence.
ACCESSION   DADVXB010000137 DADVXB010000000
VERSION     DADVXB010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.142"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            19..909
                     /locus_tag="KB902_002346"
     CDS             19..909
                     /locus_tag="KB902_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBB6809124.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(982..1806)
                     /gene="nadE"
                     /locus_tag="KB902_002347"
     CDS             complement(982..1806)
                     /gene="nadE"
                     /locus_tag="KB902_002347"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBB6809125.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1818..3290)
                     /locus_tag="KB902_002348"
     CDS             complement(1818..3290)
                     /locus_tag="KB902_002348"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBB6809126.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3927..4289)
                     /locus_tag="KB902_002349"
     CDS             complement(3927..4289)
                     /locus_tag="KB902_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6809127.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4512..5264
                     /locus_tag="KB902_002350"
     CDS             4512..5264
                     /locus_tag="KB902_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6809128.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5404..6327)
                     /locus_tag="KB902_002351"
     CDS             complement(5404..6327)
                     /locus_tag="KB902_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6809129.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6342..6614)
                     /locus_tag="KB902_002352"
     CDS             complement(6342..6614)
                     /locus_tag="KB902_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809130.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2071 a         1350 c         1161 g         2204 t
ORIGIN      
        1 ttttaagagg tgatatatat gcaactacaa ataaacgaag aatccttacc ggtatatgaa
       61 gcattagcta gtaaaacaag gatcaagatc atccagctac tttccaaaaa aaagatgaat
      121 gtcaaagatt tggcaaaaga acttggagtg agcagtgcta tcacgacgat gcacgtgaaa
      181 aagctagagg aagcaaacat catcaaaaca gaaaaagtag gacaacaaaa aatttcgagc
      241 cttcgtgtcg ataaaatcga tatcagtttt ccagaaaaaa tattcaatgc ttttgatacg
      301 aaagaaacat cgatacctat tggtcactat acaaattatg caattgaacc aacatgcggt
      361 ttagctacga tccatgattt tatcgggaaa gtggatgaac cacgctattt tatggatcct
      421 cgaaggatgg atgcccgcat tctctggttt accagcggat ttgtcgagta tcaggcacct
      481 aattttttaa atacagagga tacattggag atgttggaag tttctgtgga aatttcttct
      541 gaatttcctt tttcaaatga caattggcct tcagatatca ctttcagcct aaatggtgtg
      601 gagctaggaa catggacgag ccctggagat tttgctgata tccgcggtaa atatacgcct
      661 gattggtatc cagataatct taatcaatac ggcttgctga agacgatccg aattaccaaa
      721 cacttgacga atatgaatgg agaacccttg tcaaacatca cgatcaacga catccctaaa
      781 gagcaagaca cttggcattt gcgaatcgaa gtgaaagacg atgccaaaca tgtggggggc
      841 tgtactttat ttggtaaagg attcggtaat tacgatcagg atatcaaatt aaaagtttac
      901 tacagctgat atttttcttt tctattttat aaaacaaaaa cagccaatcc ctatgaaggg
      961 acggctgttt ttgctttatt gttatttcca gaaatcatcc aaaacggaaa ttggcaaatg
     1021 tcgtttatgt tgtgtcttgt tccaccatgc ttcgattttt tcttgtgctt gagcgggaac
     1081 ttcttttcct tctagataat catcaatttc attatatgtg acacctagtg cgacttcatc
     1141 tgcaatcatt ggtttcccat cttcaagatc tgcagtcgga atttttgtgt ataatttttc
     1201 cggtgcattc aatgcttgaa gcaattgttt cccttgtcgt ttgtccaaac ggaataatgg
     1261 caaaatgtcg gctccaccat caccaaattt cgtgaagaat ccagtaatgt tttctgcagc
     1321 atgatctgtc cctaatacgg ctcctgctct ttctccagct acggcatatt gcgtaatcat
     1381 acgttgacgt gctttgatat ttcctttgtt aaaatcgctg attcccacac ctgcttcgct
     1441 taatacttgt acttgtgcat caacagctgg tttgatattt actcgcagac taacatcggg
     1501 ctggataaag tcaagagcag cttttgcatc ttcttcatct gcttgttcac cataaggaag
     1561 acgaacagcg ataaattgat agttttcatc ttttgtttct tcacgcattt cttccatcgt
     1621 tagttgcgcc aaacggcctg ctaaagtaga atcttggccg ccgctgatac ctagtacaaa
     1681 agttttaaga aacggatatt ttttcaaata tgctttcata aagtcaatac ttttacgtat
     1741 ttcttctttt ggatcaattg ttggtttgac acctaattca ttgataattt ctgtctgcag
     1801 gctcatttat tctcctccta tgcttctgta tgaagttctg ctacgctttt tttcattcgt
     1861 tccatgatag ccattttatg gttccagcat tcagtagaca gatcgactgg gtatttttgc
     1921 ggattcaagt ctcgtttata ctcttcccat agtgaatcta gattttcttt tgtatattct
     1981 ttgatttcgt ttagtgcagg taattcgtaa actctttttc cttcgataaa gatatcttgt
     2041 aaaactgggc gagctgtaaa gtctcgaaca gttttattga taaacgtatg cactggatgg
     2101 aacatgaaga tagcttcttc ttctcgaggg tcttcatccc ataatgtcac gtagtctcct
     2161 tcagatttcc catcaaaatt tcgagtgatg cgccacactt gttttttccc tggagtagtt
     2221 actttttctg cattgcttga taacttgatc gtatccatca tttttccttc atcatcttcg
     2281 atcgatacta gcttgaatac tgcaccaagg gctggctgat cataggctgt gatcaatttt
     2341 gtcccaacac cccatacatc aattttagct ttttgcatct ttaaattcaa aatcgttgct
     2401 tcatccaagt cattcgaagc atagattttt gcttccgtaa atccggctgc atctaattgt
     2461 tcccgaacac gcttagatat ataggccata tctccactgt cgatgcgtac gccttggaag
     2521 ttgattttgt cacctaattc tttcgccacg cgaatcgcac ttggcacacc tgatttcaac
     2581 gtatcataag tgtcgactaa gaacacgcag tctttatggg ttttagcgta ggccataaat
     2641 gcttcataat catttccata agattggact aacgaatgag catgggtccc gctagctggt
     2701 atcccaaata tcttcccagc acgtacattg cttgttgcat ctgctccgcc gatatatgcc
     2761 gctctagttc cccagactgc tgcatccagt tcttgtgccc gtctagttcc aaattccaat
     2821 agtggatctt ctccgatgac agatttgata cgagctgctt ttgtcgcgat caacgtttgg
     2881 aaattgacca tattcaacag tgctgtttct actaattggc agtgcgctaa aggcccttcc
     2941 acttggatta atggttcatt tgcaaaaact agttctcctt cacgagcaga acgaactgtt
     3001 gctttaaatt caaaattttg taaatactcc aaaaaacctt caggatagac ttctaatcca
     3061 cgcaagtaag caatatcgga atcattgaac gtcagattct ctaaataatt gactaaccgt
     3121 tccaatcctg caaaaaccgc gtatccgtgg ttaaaaggca tttctcgaaa gtaacattca
     3181 aaaacagcat gtaaatcagc tcgacctaat tcccagtatg tctgcatcat attgatttga
     3241 tatagatccg tatgcagcgt caaactgtcg tctgggtaag tattattcat cttgtattac
     3301 tcctcttggc aagttttcat ttcctaccca ttataacaaa aaaaattaat aggaaaagaa
     3361 atcttccatt ttttctgaaa aagcacatgt tttacggata tttcttgcta aaaatgaact
     3421 ccatctgcta aaactatcct ttcttattgg tatttaacct aaacgagaaa gaatacttat
     3481 tttattcaat gtatccgaga cacgaagaaa ttagcgtttt ctatttttct tacttgataa
     3541 aataagtaga ttttcctact acaatcgtag ccgttaagat accgatgatt gaacaaatat
     3601 aaccaaatgt ctctacaaca taatcaatgg caaaagtttt tgaagcaata atacgtcttt
     3661 ccttttttgc ttcttatccc caaagaaacg gatataactt attatgtatt gaattttttt
     3721 ggaaaggcga attatgacaa gatatacctt gcgttgaaaa aactcgcgga aaaaatatca
     3781 cacgttttta aaaagataca aagtaagaaa gcagctgtca atagaatgga aacaaaaatg
     3841 gcgagacatc aatcagtctc gccttgtttt ttattgtata cattagatat ggagcaggtt
     3901 accataaaga tgattattag tcgttattaa atagaatcct tcgtattttt ttgttctatc
     3961 actacaatat ctttatttgg acgtttgaat tgtattccgg cacgttctag ctcctgtttc
     4021 actcctacat ggactttgac atcttctcgt gtcattttta aaacgtgatg aatcgcatag
     4081 tcgatttctt gccttgtgat ttttttcttc gtattgatca tcacgacttg ctttttatca
     4141 tatgtgtcta ccaatagcag ttgtgttcga tctaacgaaa ataatttgta ataattaata
     4201 gccgtattcc caaaaaagaa ttccactact ttaggataaa atgtcttaat atttaaatta
     4261 ctattcacag gtgtttcgat tagcttcatc tcattcctct tttctatata gtcgatttag
     4321 atccaatctt aagttatgtt accatctttc ctagcattaa ggaatcggtt acaattgaac
     4381 ctttaaagac aaaaggattt accttttatc acttaatagt ataacataat ttcgtgagaa
     4441 aaaaatacaa ttttttcttg accatctcgt tacgtaaagg attatgctta catttgtcag
     4501 gaggaaaaat aatggagtac acaataaaga aaatgtcaga gatatcagga gtcagtccga
     4561 gaaccttgcg cttttatgat gagattggac tgctaaaacc agctaggatc aattcttcag
     4621 gttatcggat ttatggcaaa aaagaagtcg atcgtctgca acacatctta ttttatcgaa
     4681 caatggcatt caagttggat gatatccaag aggtcttaga caatccatct tttgaccacc
     4741 agaaagcttt aatcaagcat cagcaaatgt tgctggaaaa acgggcacaa atcgataccc
     4801 tcttgacaac tgtccaacag acacttgata tgtacgaagg aggaagaaaa atgagtgaca
     4861 aagaaaaatt tgaagggttt aaacaacaaa agttgaaaga aaatgaagaa tcctatggac
     4921 aagagattcg acaaaaatac ggaaaaaaaa aggttacagc atccaatgaa aaatggatga
     4981 atatggataa agaaacgtat gaagaaatgc aaactgttga aaagcagatg ttatttgatc
     5041 tcactcttta cttaaaagaa ccagaagatg aaagcttagc agaccgtatc ttccaagctc
     5101 ataagaagtg gttctcttac agctggcctg aatatcagcc aaaagcgcat aaaggactag
     5161 gaatgatgta cgaagccgat gaacggttca ctgcatatta tgacgagcga agtggtcatg
     5221 gtgcagcaaa agctttaaat gaaattatcc aaaaaaaggc gtaatctttt acatgatcca
     5281 acaaaaaagt acacgtaaaa tgacctaata acaaaacagc agacacccaa gttagatttt
     5341 tatgctaact tttggtgtct gctccattct ttcacaagtt ttttcatcct actttaaata
     5401 tattcatcgt tgaataaacg tataaggtat tttcacttta tccttttttt ctgtaagaaa
     5461 caattgaaat gccatttctc cgcaagcttc cagatggtgg tcgatggttg ggaaaccaag
     5521 aagctcgctg atcagcaaat tatcgcgtcc aatcaccact ggtgtcttat cttgcagata
     5581 gctttgcaag atgcctgctg caaccatatc cgaatttgta aagacaccat caactccaag
     5641 ctctttaaaa aagaagcctg cttgttttcc tttctctgca tctatacaat cccaaaaaac
     5701 aagtgattca tcaaaagatg gaaaaagttg atgacatagc tgcaaagtga tttttgagtt
     5761 ataacttagc ctgccacttc gccccaacgt gatgcccaat tgctttatac cttgctgctt
     5821 caaataagta agaccttctg taattgattg ttctcgatca ataaagacac agcttgcctg
     5881 ttttcccttg atttcttcac aaaaaactag aggtccatat ttttgatatg ccaataaatc
     5941 atctagtgta ttggcacgag acgtaatgat caatccatcg aaagctttag ctgcaaattc
     6001 ttcaagatac cttcgctctt tttctttatg atagcccgtc ggtaaaagtg tcactttgta
     6061 atcataatca aacgctgctt caatgatccc actgatcaac tgatcaaaat acggatgatt
     6121 ggtataaggc agaatcactc caatgctttt cgtttttcca taacttaact gtctggcatt
     6181 tgcattaggg atataatcga cttctttcat gaccgcaagt atttctttcc ttttttcctc
     6241 atctacatat ggatgtccat tgattacacg tgaaatagta gaaactgaat aacctgtgag
     6301 ctttgcgata tctcgaatgt ttgccactgc tgcttcgcca cctatacaaa aagattttct
     6361 tgtaaatagt ctaccacagc tggaccgcat tcaaaaaact gatacatttt tccttcatgc
     6421 gaaaaactga tccgctgccc gccccaatat atatcttttg tcaaattttc gatttcattc
     6481 attggtattt cttttactat attcctattc aacccttgaa aactgtacaa cgttaatacg
     6541 gatcccttga actcgacaaa cgcataaaaa taattgttcg ttgtgccatc tgttatctct
     6601 acataagtat tcattgcaag ccctcctttt gatactttga gtatagtgta tgaaacgcgt
     6661 ctcatagcaa ggagtttgtt ttgccaaaga aaagttttat tcctctttca ttattaccaa
     6721 agtctcttat tttaaattga atacattata atgatactgt aaatatatct ttattattag
     6781 tgaatg
//
LOCUS       DADVXB010000138         6602 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.143, whole genome shotgun sequence.
ACCESSION   DADVXB010000138 DADVXB010000000
VERSION     DADVXB010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.143"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            242..2473
                     /gene="pflB"
                     /locus_tag="KB902_002353"
     CDS             242..2473
                     /gene="pflB"
                     /locus_tag="KB902_002353"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBB6809131.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            2717..3478
                     /gene="pflA"
                     /locus_tag="KB902_002354"
     CDS             2717..3478
                     /gene="pflA"
                     /locus_tag="KB902_002354"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBB6809132.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            3563..4489
                     /locus_tag="KB902_002355"
     CDS             3563..4489
                     /locus_tag="KB902_002355"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBB6809133.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            4671..5564
                     /locus_tag="KB902_002356"
     CDS             4671..5564
                     /locus_tag="KB902_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBB6809134.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            5698..5823
                     /locus_tag="KB902_002357"
     CDS             5698..5823
                     /locus_tag="KB902_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6809135.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5957..6589)
                     /locus_tag="KB902_002358"
     CDS             complement(5957..6589)
                     /locus_tag="KB902_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809136.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
BASE COUNT         2392 a         1104 c         1300 g         1806 t
ORIGIN      
        1 attaatacag gtggcgtctc tttttcattc atttttaata aatccttata cgtttgcaaa
       61 aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat ttaaatatat
      121 gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa agatagggtg
      181 ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg aggtccatac
      241 aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag acactagaga
      301 ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg aaggcccaac
      361 agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc aattcgagcg
      421 taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac acgatgcagg
      481 ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac ctttgaaaca
      541 agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa gcaatggcta
      601 tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac ataatcaagg
      661 tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa tcattacagg
      721 gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg tggcattgta
      781 tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg gttatcatac
      841 aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc gtgcattagc
      901 gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag ctgcaaatgc
      961 aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat cacaaaatgg
     1021 tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc aacgtgattt
     1081 ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact tagtaatgaa
     1141 attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct caggattccc
     1201 tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat tagttacaaa
     1261 gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag aaccaaactt
     1321 gactgttttg tattctgaac accttccaga aggattcaga acatatgcta gcagaatcgc
     1381 tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac aatggggttc
     1441 tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag acatgcaatt
     1501 ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg gcggagtcga
     1561 tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag aaatactaga
     1621 ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag aactatatgt
     1681 caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag cagctcagct
     1741 ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg ggatctctca
     1801 tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc gtaatgaaaa
     1861 aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa atgatgatga
     1921 ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa tcaaacgtca
     1981 taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt caaatgttgt
     2041 ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac cacttgcgcc
     2101 aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc tgaactcaac
     2161 agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa caatcaatcc
     2221 ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg tcttagatgg
     2281 atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg atttattgcg
     2341 tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat ctggttatgc
     2401 agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga gaacttcaca
     2461 cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa aggacgttga
     2521 atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac gatttacagg
     2581 ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg caattgcgaa
     2641 aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg aaatcaaaga
     2701 aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta tcgaaacttt
     2761 cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat gccgcatgcg
     2821 ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag aatacacagc
     2881 agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata aaggtggtat
     2941 tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac tatttaaaaa
     3001 agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt ttacgtatga
     3061 agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac tgttatttga
     3121 catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca atgaaaatat
     3181 tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc gccatgtact
     3241 agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact ttattcaaac
     3301 cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa aatacaagtg
     3361 ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa aagaacgtgt
     3421 cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa cgcgataggt
     3481 cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat taaataggag
     3541 aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc aaaatccaga
     3601 tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat taggtaaaga
     3661 aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat tagaccactt
     3721 tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag atgtcatgct
     3781 tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa atattttagc
     3841 tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt actatcgtgc
     3901 agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa accaagtaac
     3961 aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata cattgttgtt
     4021 caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg cagcaatcgc
     4081 tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa atctaagtga
     4141 taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg gcagttccaa
     4201 cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc gacaagcaga
     4261 gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt tcgtattagt
     4321 tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag gaaaagaaaa
     4381 agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta aaggtgtcgt
     4441 ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat caaatggtag
     4501 tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat agaacatact
     4561 aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct tcctcctttt
     4621 tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat atgaactatt
     4681 attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt ttttcttcat
     4741 tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa ttgaaaaaag
     4801 aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca ggattaatca
     4861 agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa gattacttgc
     4921 aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc tctgttgatg
     4981 aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat gaacggaaag
     5041 aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg acaactgcag
     5101 gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg cttactttgg
     5161 ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc aaagaattag
     5221 ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa gttatcgttg
     5281 acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat cagtctctac
     5341 ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct attgtcgaaa
     5401 aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg gaggaaatgg
     5461 cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg catgcatttt
     5521 cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc agtaagcaaa
     5581 aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa agaattattt
     5641 gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa caaaggaatg
     5701 caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa agttagattt
     5761 ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga actagctgat
     5821 tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc gagtcattaa
     5881 taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta aaaaagcatt
     5941 tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt tttctttgcc
     6001 acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct gcgacttgga
     6061 tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac aagctgtaaa
     6121 taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg ctaaaaatga
     6181 gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc atgataaaga
     6241 agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa aacgttttaa
     6301 atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga aaaaaatagg
     6361 caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa aaaaacggat
     6421 tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat gcactagaag
     6481 gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc aaagttgcaa
     6541 aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata atatctccaa
     6601 at
//
LOCUS       DADVXB010000139         6352 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.144, whole genome shotgun sequence.
ACCESSION   DADVXB010000139 DADVXB010000000
VERSION     DADVXB010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.144"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            120..497
                     /locus_tag="KB902_002359"
     CDS             120..497
                     /locus_tag="KB902_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6809137.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            485..823
                     /locus_tag="KB902_002360"
     CDS             485..823
                     /locus_tag="KB902_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6809138.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            957..1400
                     /locus_tag="KB902_002361"
     CDS             957..1400
                     /locus_tag="KB902_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBB6809139.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            1662..2477
                     /locus_tag="KB902_002362"
     CDS             1662..2477
                     /locus_tag="KB902_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6809140.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            2487..3149
                     /locus_tag="KB902_002363"
     CDS             2487..3149
                     /locus_tag="KB902_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6809141.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            3354..5018
                     /gene="alsS"
                     /locus_tag="KB902_002364"
     CDS             3354..5018
                     /gene="alsS"
                     /locus_tag="KB902_002364"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBB6809142.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            5031..5741
                     /gene="budA"
                     /locus_tag="KB902_002365"
     CDS             5031..5741
                     /gene="budA"
                     /locus_tag="KB902_002365"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBB6809143.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            5871..>6352
                     /locus_tag="KB902_002366"
     CDS             5871..>6352
                     /locus_tag="KB902_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBB6809144.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     S"
BASE COUNT         2074 a          998 c         1356 g         1924 t
ORIGIN      
        1 tatagataat ccagcttagt tttaatagaa atgagtattg acttggagta cacttaaagt
       61 tgtagaataa ataaaataca taagtaaagt ggcaagaaat taagagaaag agtgatcaga
      121 tgaatatcaa acaagtcagt gaagaaaagg gcatttcggc cgatacattg cgctattatg
      181 aacgaatcgg gttgattcca ccagttaatc ggacaaaagg cggaatccgt gattatacag
      241 aagaagacct aaaatgggtc gactttacga tctgtatgcg aaatgccgga ttatcgatcg
      301 agtctttgat tgaatatatt cgcctatcta gcgaaggaga agcaactgta tttgagcggc
      361 gtaagctttt gattgaagaa agtgaacttt tgacgaaaaa aattgctgaa atgcaagaat
      421 gtttggaacg tttacaagga aaaatcaaga aatatgatcg tgtgttatct agaaataaaa
      481 tggaatgtat caagtaaaaa aatcaaggag catcgctatg gagttacgct tactaaaata
      541 tttttggaca attgcagaag aaggaacaat ctctcaagcc gcagaagttc tacatcttac
      601 acaaccaacc ttaagccgac aactgaagga gttagaagag gaactaggaa cagaactgtt
      661 tgtacgcgaa aaccgcaaaa tgatcttgac agaagcaggt tattttctaa aaaagccgag
      721 cagaagaaat tttagattta acgaatcaaa ccactcaaga attcgagaac agaaaaaaac
      781 aattattcag cggccgattt acgatcggct gtgtggaagc tgataattcg aatacattgg
      841 cactattact agaaaagttg atccgtgatt atcccagcgt tcaatttcat atccacagcg
      901 gaacaagtga tgatatcacg gagtgactag aaaaaagcct gttagattta gcgattttgc
      961 tagatccagt agatacagag aaatacgaaa cgattttgtt accaagaaag gaaaaatggg
     1021 gattgctcat tttagaaaat tctgttttag caaaaaaaga cgtgataaca aaagaagact
     1081 ttgcgaatgt acctcttttg atctcaaagc gtccagaaat acagcgaatg tttgctgact
     1141 ggttaggcat aaaaaaggag cagttgctga tcacaggaac gtacaatttg attttcaatg
     1201 tatttgcgct aattgagaat caggtaggtg ctgctttagt catagaaggt gctgtaagtc
     1261 atctttcaaa gcgagtgaca ttcgttccgc ttgacccaat gattgaaacg aactgcatgc
     1321 tagtctggaa aaagaatcgg attttatcac ctgtagtcaa tgaattgatt caccgtttca
     1381 aagaagcttt tgaacagtaa taagtatctc taatcgaaga aatttcaata caaaagcgag
     1441 acgtatgaca gtcttgcttt tgtatttttt catttttaaa tcaaaaaaaa taaagagatt
     1501 tacataactt gttaaataag cgcttacaaa cataagaaga acggaaatga atcagctata
     1561 ataaccgttg ttctggattg taatcattac aaagaaatga agattataac tttggaggtg
     1621 ttcgaaatga aagaaaaaaa gcaaaaattc gttcaaaaaa catgcccttt attcaatggt
     1681 tgggtatgat tctgctgatt gtattagctt tattgacgat cattcctttt ttatggatgg
     1741 tttctgcttc attcaaagca aataatgaag tgttcacgat tccgattcaa tggatcccta
     1801 aaacttggca tttagagaat tatctggtta tttggtctcg tattccttta gtgacatttt
     1861 ttaagaatac agctttttta agcgttgtga tcacgttgat tcagttgttt acttctagtt
     1921 ttgctgctta cgggttttct aaactaaatt ttaaagggcg cgatatttta tttttagcat
     1981 atatcggcac gattgctgtc ccttggcagt cttatatgat cccgcagttc attatgatga
     2041 gaaaagtggg tttaacatat acgttgtggt cgttggtgct attacaagcg ttcaatgctt
     2101 ttggtgtgtt cttgttgaag caatactaca gtagtatccc agattcttta tgtgagagtg
     2161 cgcggatcga tggcttatca gagtggggaa tctatcgcaa gatcatttta cctcttacaa
     2221 aaccggcgat tgccagtttg acgatcatca cattcgttaa tacatggaac gattatatgg
     2281 ggccattcat ttatttgtct tctacggaaa ataaaacaat ccagttaggg ttgaaaatgt
     2341 ttattgggct atttgatgca gagtacgcat taatcatggc tgcctcagtt gtttctgttc
     2401 ttcctgttgc ttttatattt ttagcgatgc aaaaatattt tgtagaaggg atcgcttcat
     2461 caggaatgaa ggaataggag gtgattatga aagagcagcg ttttgacaaa aatgtttata
     2521 tggaattctt ttattggttg tatcaatcat tggcaagtag cctttgtttt tggtgtgtca
     2581 atatcttgta tatagcagct gcgttccttt tgtcgataga tggaaggaat gtcttttcct
     2641 ttattttttc tttacttttt attggtccag gttgcatcgt gatgataggt atgacagaag
     2701 aattagcaaa agaaaaaagt ttttcaccag tacgtttgtt cataaagacg tttcgccaat
     2761 tttggctaaa gggatttttt tattggctat ttgcttggat agttagtgtg ataatgattt
     2821 ttgattgttt cttttttata cgtttttctt atggaaaatg gttgattccg ttgtttgttt
     2881 tacttgcttg tttatcagtt tcctttagca tcaactactg gtattttcag gtgagaaatc
     2941 cagcgtcgaa accaaatcaa gttctacgga tagcgttcta ctatacgttg aaaaaatggt
     3001 atgtgagttt actagatttt ttactattga caagtttgtt tctcttcttt ttcgtaaagc
     3061 cccaatggtg tattctacta ggtccttcta tcgtatttgg tttgatttac ttcaacaatc
     3121 gtaaattgat gagaactatg gatctgtaga ctttataaat tgaaactttc aattaagaat
     3181 gacagttttt atgtaaaaac tgtcattctt tttcattttt tgaaacatat ggctaaacaa
     3241 atgaaataaa acgtgctata cttttgaatg aaacaggttt agaaactgta tcaattattt
     3301 gtgattattt ctaactaata attaaaaata aagcataaaa aggacgatgt tcaatggacg
     3361 aaaaaatgaa acaaggttcg aaatctgtag tagaaagttt gattaatcat catgttgatt
     3421 atgtattcgg tataccaggt gcaaaaatcg atggtgtatt taatgaatta gaggatcaag
     3481 gtcctgaatt aatcgtgact cgtcacgaac aaaatgctgc atttatggca caagcaatcg
     3541 gacgtattac aggagagcca ggagtagtta tcgcaacaag tggtcctggt gctagtaact
     3601 tagctacagg tttggtaaca gcgacagcag aaggtgaccc agttttagca attgccggac
     3661 aagtaaaacg aagcgatcta ttgaagttga cccatcaaag catggataat gcagcactgt
     3721 tccagccaat cacaaaatac agtgcagaaa tccaagatcc agaaacaatt tcagaagtga
     3781 ttgccaatgc ttatcgtatg gctaagagtt caaaaaaagg cgcgagcttt atcagtatcc
     3841 cgcaagatgt agtggatgca cctgtccaag ggaatgtcat caagccattg agcgatccta
     3901 aattaggttc tgcttctgca gatgatatcc gttacctagc tgaacgcatt agagaagcaa
     3961 aactaccggt actattagta ggtatgcgag gatcaagtga aaaagaaacg ttagccatca
     4021 ggcaattagt tggaaagaca gcattgcctg ttgtagagac attccaagca gctggagtga
     4081 tctcacgtga attagaagcg catttctttg gtcgtgtggg tttatttaga aaccaaccag
     4141 gagatatgct tttgaaacga agtgatctag ttattgctat tggctatgat ccaatcgaat
     4201 atgaagcaag aaactggaat gcggaaaaag atgcgcggat cattgtgatc gatgaagcgc
     4261 cagctgaaat cgatcctttt atgcagcctg aaagagaatt gatcggtgat atctcagcca
     4321 ctcttgattt attgacaggt tcattagagc ctcaacaagt gtcagaagat gcaaaagaat
     4381 atttagcatc tcttcaagca gaattaacgg agcgggacat tgttcaatca aaaggagaag
     4441 caggtatctt gcatccttta gaagttatta acacgcttca gtcaaaagta acagatgata
     4501 tgactgttac cgtagatgta ggtagtcatt atatttggat ggcacgccac tttagaagtt
     4561 atgaacctcg tcatttgtta ttcagtaatg gtatgcaaac gcttggtgtt gcattgccat
     4621 gggcgatttc tgctgcattg gtgcgtccaa atacacaaat cgtatcagtt tccggcgatg
     4681 ggggattttt attctctgcc caggatttag aaacggcggt acgtaaaaaa ttgaatatcg
     4741 ttcatttgat ttggaatgat ggacactaca atatggtaga gttccaagaa aaaatgaaat
     4801 atcagcgggc gtcaggtgta gactttggtc cagttgattt tgtgaaatat gcagaagctt
     4861 ttggcgctaa aggaatccga gctacaagtg tagaggaatt agaaaaagct ttagaagaag
     4921 gatttgcgac agaaggaccc gtaattattg atattccgat tgattaccgt gataatgaga
     4981 aattgggaga aacaatctta ccagatcaat tctattaagg aagtgtcgac atgactgaaa
     5041 aaatcttata ccagcacggg acattaggag ctttgatggc tggcttgatg gatggaacag
     5101 aaacgattgc tcatatatta gaaaaaggaa ctctgggatt gggaacattg catgggcttg
     5161 atggtgaagt catcttttta gatggcgtag cttatcaagg aagatcagat ggctcagttg
     5221 cccaattaga tggaagtgaa cttaccccct atgcagcaat tacagatttt acgccagata
     5281 ctagtttttc tgtctcaaaa actgcagatg gagaacaatt gaaaaaagac atattagtaa
     5341 gagaagccgg ggaaaaccta tttttggcag tgaagataac tggattattc aaaaatatgc
     5401 acatccgtat catgccgaag caagaaaaac cttacagaag actagcaaaa atttcagagt
     5461 ctcaaccaga attccaacaa agcaatgtcc aaggaacatt agtcgggttc tttacgcctg
     5521 aattattcca aggagttgct gcagcgggat ttcacttgca ttttatcgat gatacacata
     5581 catttggcgg acatgtaatg gattttgaag tggctgaagg aaaagttgag attagccgca
     5641 tctcgtccct tgtacagcat tttccagttg atgatccgac ttttgttcac gaaacgattg
     5701 attatgctga tttagcagca gaaatccaac aagcagaata gaaaaagaca gcgagatgcg
     5761 ttcaaggtga ttaacctgac gtatctcgtt tttttgagga ggaaacctag cgtttacaaa
     5821 aaaactgagc tataatcttc tccatagatc aaaaaggagc ggtttttatc atgtggacag
     5881 aaaaacagaa aaaagatgca tacgaaattt tattattaca gcaacaagga ttattagaag
     5941 cagaagataa ctggttagca aatttagcaa attcatctgc attgttgaat gagactttgc
     6001 ctgagactgt ctttgcagga tattatttat tcgatggtaa tgaattgatt ttaggaccgt
     6061 tccaagggcg agtttcttgc acacgtatca agatgggaaa aggagtttgt ggagaatcag
     6121 ctgaaaaaca agaaacattg atcgttgatg atgtcaaaac ccatgcaaat tacatttcct
     6181 gcgattcagc cgcacaatca gaaatcgtag tgccaatggt aaaagaaggt aatttaatcg
     6241 gtgttttaga tatcgattgc ggagtaacga aagggtatga tgaaatcgat caagcatttc
     6301 tagaaaaata tgtagatctt ttattagcaa attttaatat aaatgctttt tc
//
LOCUS       DADVXB010000140         6334 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.145, whole genome shotgun sequence.
ACCESSION   DADVXB010000140 DADVXB010000000
VERSION     DADVXB010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.145"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(1041..1706)
                     /locus_tag="KB902_002367"
     CDS             complement(1041..1706)
                     /locus_tag="KB902_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809145.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            1886..3868
                     /locus_tag="KB902_002368"
     CDS             1886..3868
                     /locus_tag="KB902_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBB6809146.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            3872..4510
                     /locus_tag="KB902_002369"
     CDS             3872..4510
                     /locus_tag="KB902_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809147.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4538..4966
                     /locus_tag="KB902_002370"
     CDS             4538..4966
                     /locus_tag="KB902_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809148.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5423..6334
                     /locus_tag="KB902_002371"
     CDS             5423..6334
                     /locus_tag="KB902_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6809149.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2183 a          966 c         1174 g         2011 t
ORIGIN      
        1 acatcaaggt tcctagcctt tttataataa aatgaagcga aaataatttc ttttaaagag
       61 ccgagattat cagctatata agagtgaatt tgatgcaaaa aacagagccg aaacagtctt
      121 ggtgttcgta gctctgctta tatgtttcga atttaagaca aagagttggc aaaagatgtt
      181 gataaggaag ataagataac tgtgttatat aaactaggta actaactgta acaagctaat
      241 tttaagagat tcttattaga agacgtttag gaatataact aagaaaatga ttatacaggt
      301 aattgtcatt tcaataatgt tttctaattt tcgcgtcttt gttttaagaa aaaggccaga
      361 atcagttgga aaaaagttcg tacgatagtg aagaggggca aaatttccta ctaatattcc
      421 cactaacaag agataaaacg gccaggttgg tgtgattcct ctataaaaaa atgcccatgc
      481 taccgaaatc ccatagatta acaactgaac aatttttaca atgaaaaaat tgttctgcca
      541 ttactcaaag tctcttcctc cttgtatcgt ttatttgttt cattttatca ttatgatagg
      601 cgcttgaaca atccattttg tattttattg agtactcttg gataaactac cagcgattat
      661 catatttatt tatgttactg taagccatca tataaaagta aatgagcaga tcatagaaat
      721 ataaaaaaga actaaaattg atctaaatta tgtgcagctt gactacgtac caatctatat
      781 tacttactag attggtcgtt aatctattcg gatcgaatga gcaaaatatt tttgtgaatg
      841 tccatccttg attatgattc caaaaagaat cattgggagg ctgtggcgta aatattatac
      901 tataagccag aaatacctat cattctgaac ttttttattt aggaactttc atctcaaggc
      961 tttttcaatt aatttgtacc cctgtttttt ggataagatc atgtgcattg attttttcta
     1021 tctctacgtt catctcctac ttaatgccta tctggctcct gagggcttct ttttaaggcg
     1081 tcgtcatagt cttggctgag gatttcttgg taatctgagg gaatggcttc ccaagtgagc
     1141 aggcgaacgt tcatgacgtg ttttcctttg tgtttgatta cagcatggtt tttctctttt
     1201 tctacctctc cagcgtgaaa agacagccat gtaccatggc caaagatatc attacatacc
     1261 caacgttcga tggaattgtc cacgtatcct acagggagtg tggtatagcc gatttgtggt
     1321 ttcaaaaaag gattgaatcg atcgatcgtt tcatttttgt attgataatt gataagaaaa
     1381 agatagacca aacaaaagac gagcagaaag aaagatagtg tctttttgag tgagaagggt
     1441 tgttttgatg aataagattt cttgttaaca agaggttcat ctggcaatgt tggttctatt
     1501 gattcggtag ctgattcaat agaaggaaaa tcaatcggca gacctaaagt atgatgtaaa
     1561 agtgacagca tttcaaggtc tggcattgta cgagaatttt cccaactaga aatcgtttta
     1621 tcggaaacac caattttttc gcctaattct ttttgcgtaa gcttacaatt tctgcggtaa
     1681 gttcgtattt tttctccggt gttcatcttc ttctcctttc gattctacag tatatagatt
     1741 tattctacat gacctataca cttgatagat acgttttttt gatgaaaaac ggtatgattt
     1801 tatcaaagaa tcatttaagt aagggagagt ggtgataatc aaaaaaaagt tcacagtttt
     1861 actcacaatc atagtgaccg gtatcatgag tggttttgcc ttggttagta taaataaaca
     1921 ggtactctat cggacaaatg aatttttcca tcaaacagat acttatactc cgattcgatt
     1981 gccacaacat tttattgggc aagaagaata tgagcagcta atcatggtat ttgaaaatgt
     2041 ctcatcagaa actgagcttt cttatatgaa aaaaacagta aatgaatcca atgaagtaga
     2101 tacatcttgg aacttcaaga tacagccaaa gcttgaaatg acattgtatt atcaagggga
     2161 tgtcaaatct tctcacgaga aggtacccta ttctaatacc tcctttcgcg taacgtccat
     2221 tgaagaatcg atcaaaataa aagattttga aggtgaattt ttcttgatga cgagagaaaa
     2281 agaagcctat gaacggttca tttcactatt cactgatcga ttcaatcaag catttcacac
     2341 tgattatgcc actaatattt ttgaagactt tgaaaatagc tattcgtatt cggttatttc
     2401 aaatacagac gtatataatt atcgagtgta tttaactatt ggattgattc ttttattcct
     2461 tttgttatca tcctttttct tattgatgaa taaagaaatc agtttattgt tgaataatga
     2521 cttttcatta catcaagtat tgtggtgttt attggggaaa aagaaaatca ttattacatt
     2581 cataattgca ggaatcattg gtggttttat ttttatgtat tataaggagc aatttcttta
     2641 tttgttccag atgtacgttt tcttgttcag cggaatatat ggtatctctt tgatttctct
     2701 tttattagtt gaaaaaatcg cttcgttaag agaagcgttc aactatatcc aatacattct
     2761 ttttacattt ggattgttgt tttctcttct tttgaccgtt gccaatgtcg aattagcaac
     2821 tatcgttttt tcttcttcac agttagctgt ttcccatgaa ccaccaaaag aaatcgctgg
     2881 tgaggactat catgtatttt atccagtaac catcgggaaa aaccacgtgg attttattta
     2941 ttccaatcgt tttgcatcag cagcagatca ggaattatat gaaactttga ataaaaacgg
     3001 aagtatatta gtcaatgtat cagattactt gaatgaagaa aatgaacagt ttggcagagg
     3061 gataaaaata aatctgaatt atcttaagaa atttcctttg attgatgtct ctggaaggtt
     3121 gatccaaata accgaaaaag aaacgcaccc tgttatattg atccctgaac gatatagaca
     3181 tacagattta aaaaatgacc tggcgcaaat aacagaatat tatcaagaaa tcagtgaaaa
     3241 agaaccgaaa tttctattta taaaaaacaa tcaacccatt tatacattta ttccttctat
     3301 cccctggatc gaacattatc cggttgttga aatactgaca ttgaaaaaca gtatgtattt
     3361 ggaaagaaat attctcagcg gagaaatcta tccaccgtta aagatcaaga taggctcttt
     3421 gtcgaaagaa aggttatttg agctgattga agaaagtcag ttacgtgata acttgcagtt
     3481 atcatttccg tatactcaga ctgaagagat agctgtcaaa gtgttaagca gatcatttca
     3541 ttacttgata cagatatttt tactcacttt cttttctttc ttcttgttga gctatgtcat
     3601 gttatgcata tattttgtct acaattgtcg gaaaatcgct atctttcgtt caagtggtta
     3661 ttcgctcttt gaaacgtata aagatttctt catgatgaac ctcatcaaat ggggaacgac
     3721 aagtgtaatc ttcctttttc ttatagaaag agagcctaaa tatcttttta atattttttt
     3781 ctttagcttc attgatttta ttctttcagt tgtttttatt ttgtctacag aaaagaaaag
     3841 tcagttattg ctgatgaatg gaggttaaca attggagccg ttgatagtga taaaaggtgc
     3901 gaaaaaaatc attcgaaaca aaacgattct tcatttggat cgtttcactg cggatgctgg
     3961 ggatcttgtg actgttgttg gagaaagtgg agcaggtaaa agtacgttat tgaatatatt
     4021 aggattgaat gatcagttca gttcaggaca attctatttg ttcgatcaag agacgaaaca
     4081 attaactggg agagagaagc gcttgataaa aagaaatacc atatcttttc tttttcaaga
     4141 ttttgggttg attgaatatg aaacaatcga ttttaattta gatattggat tgaagttttc
     4201 gaatttaaat gtttcagata agcgaacagc aaagtatgag gcattgaaaa aagtaaatat
     4261 aaacaagaag ctaagtacgc ctatctacac attatctggt ggtgagaagc aaagaatcgc
     4321 ctgtgcgaga gtcttattga agaatagcaa aatcatttta gccgatgaac cgactgggtc
     4381 attggataaa agaaataagg ataaagtagt tgaaatctta tcgcaacaag cttcccaagg
     4441 tacgttagtt atcgtagtca cgcatgatcc atatctgacc aaaataggaa acaagaagat
     4501 catgctttaa aaatcaaaaa ggaaaggatg tcgttttatg aaaaaagcag ttattatttg
     4561 tgcactaggg ataggttttg ttggaggaaa cgctatgtca tctgaagtgg aagcaaattc
     4621 agttcacggt gaaatctatt acaaatcttt aaagccagga gagattcatt ttgatgctaa
     4681 aggtaatatt attaagtcaa atttaccagt agaccgggaa atttctagaa cagcaattaa
     4741 tcatagctct ggaagatggg tttattatag tgatacaact tgtacgagaa aaacaggtca
     4801 ttctaaccac tatagtcgtg tctataatcg tcacggtgca aaagcgaaag ttggaaactc
     4861 tattcgatca gcaaatgcaa caaaaggagt atgggcctat gcaagtgcga caggaaatag
     4921 aactgacaca ttctcatgtt ggtacaatcc aaccggttgg tattaagtat ccaaaagttt
     4981 atataaaata gaaaaaacat ataatgaaac agcgttaaaa gttatttttg gtagttttaa
     5041 tatattcatt tttagttgta taaaaatata tcataataaa aacaacaaaa aaatgtctgg
     5101 aaaatcgaac ataaaagtgt ctgatttgaa tatcccagca gcggaagaag aaaaacaaaa
     5161 tcgataacat ttgttctaag aattagttac gttaaatacg gaacgcaaga tagacttgaa
     5221 aaacggtaac aaaagaagta gtatattaag gtgtgatgtg ctacttgaca tttattctgc
     5281 tgagcgaact ttctggattg tgtagcctta tatctattca ggacgtatcg agcagattag
     5341 taaaggtgtt cttgatgatt ttcatcttga acacctttgt ttttagcaat tcgcaaaaaa
     5401 cgaaaagtag gagaattgat aaatgaaaaa aagattttta gcacttgcca tcgtactagg
     5461 cactggctta ttgtcaggct gtacgaatgc cggtgaaaaa acagccgtta gttataaagg
     5521 cggtacaatc agcgaacaag aagtaatgga tagcttgaaa aaaatgcaag gagcagattc
     5581 cgctgtgcaa cagttgatcg tttatcaagt atttgaagat aaatatggag atgacgtatc
     5641 aaccaaagaa atcgattctc aatatgatca aacaaagaaa caattgggtg attcatttga
     5701 ttcacaattg aaatctgcag gttacacaga acaaacattc aaagacagta tcaaacaaag
     5761 tctagccttt caagaaggtc taaagaaaca tatcaaattg accgatgaag atttaaaaac
     5821 ggcttgggaa tctttccatc cagaagtgga agctcaaatt atccaagtag caagtgaaga
     5881 tgatgcaaaa gatgtgaaga aagctgctga taagggagac gatttctcta aattagccaa
     5941 agacaagtca actgatacta cgacaaaaga agatggcgga aaagtgaaat ttgattccac
     6001 tactacaacg gttccggcag aagtcaaaga agcagccttt aagttgaaag atggtcaagt
     6061 ttctgatgtg atcacttcta ccaatgcttc aacttatact acggaatatt atgtggttaa
     6121 aatggtgaaa aaccaaaaca aaggcaacga catggataaa tacaaaaaag aattgaaaga
     6181 aattgcaaca gacacaaaat taagtgacag taccttccag aataaagtaa ttggcgaagt
     6241 attgaaagac gctaatgtaa aaatcaaaga caaagacttt gaaaatgttt tgagtacatt
     6301 cacttcagat tctagtacag caagtagtaa ataa
//
LOCUS       DADVXB010000141         6323 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.146, whole genome shotgun sequence.
ACCESSION   DADVXB010000141 DADVXB010000000
VERSION     DADVXB010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.146"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(98..1228)
                     /locus_tag="KB902_002372"
     CDS             complement(98..1228)
                     /locus_tag="KB902_002372"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBB6809150.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="KB902_002373"
     CDS             complement(1877..3079)
                     /locus_tag="KB902_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6809151.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="KB902_002374"
     CDS             complement(3139..3342)
                     /locus_tag="KB902_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6809152.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="KB902_002375"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="KB902_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="KB902_002376"
     CDS             4879..5691
                     /locus_tag="KB902_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809153.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1880 a         1299 c          997 g         2147 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaa
//
LOCUS       DADVXB010000142         6244 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.147, whole genome shotgun sequence.
ACCESSION   DADVXB010000142 DADVXB010000000
VERSION     DADVXB010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.147"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            349..705
                     /locus_tag="KB902_002377"
     CDS             349..705
                     /locus_tag="KB902_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6809154.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            715..1614
                     /locus_tag="KB902_002378"
     CDS             715..1614
                     /locus_tag="KB902_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6809155.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGKLLDHYSNIKQVVF
                     GHTHRRFEDQLIHGAIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            2131..2862
                     /locus_tag="KB902_002379"
     CDS             2131..2862
                     /locus_tag="KB902_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6809156.1"
                     /translation="MMKKEIVLTATTMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRGTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            3007..5034
                     /locus_tag="KB902_002380"
     CDS             3007..5034
                     /locus_tag="KB902_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6809157.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENENLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            5142..6239
                     /locus_tag="KB902_002381"
     CDS             5142..6239
                     /locus_tag="KB902_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6809158.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMRQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVIIETKITKKGHSKVLYREEKEALQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         2161 a         1015 c         1283 g         1785 t
ORIGIN      
        1 cctccaaaga agtcttttta tttgataagt ttactctacc gaagagttgt taataatccg
       61 tgaacaaaaa gtaattcttt ttccaatagt tgttaaaggt tttttatttt ttatagtatt
      121 ttttgttatt taagaaagga ataaggttaa acaaataaca ggttgctttt tgggtctttt
      181 tccgttcaag aaactgaacg aagaaaaggg aaagttgtct cttttgtgat aagagaaatc
      241 ataataaacg aatgacttac tttccaataa attgagaaca gtcagaacca gacaaattag
      301 ttgcatctga tgaataaagt gattattcta tgacatgagg tgatacagat gaaattagaa
      361 gtgacaaaag aagcacaaga agtattgaag aataaattag aagcagacga tcaactttta
      421 ttagatatcg aaaacggtga cggtccattt gcagaaagcc aagtcagttg ccaattggac
      481 acggcatttc gattgatcat tgtcaaaaaa gatacacaaa cagatctaag tctttattct
      541 gtagtggctg atacaccagt tggaccaatc aaaatcaaag acagtgcaat actttacatg
      601 gatgatccat ccacacttgc tttagaacca acttataata gtttacaatt aaaaggacca
      661 agcggcttga gaaaaggcaa cttgcaagtt gttcgaaaag actagaggga taaaatggga
      721 aaattggcga tcatcagcga cctacatgtg gacatcaata aattcggcga atcagagctg
      781 atgcagcttt ggcaagtttt gcaaaagcac aagatcactc ggcttcatct agccggagat
      841 acggctaata aagtagaccg ttgcctagct gttgtcgaat ttttcgtcaa taaaggatta
      901 tctacgacat ttcatttcgg caatcacgag ttggcagatg tgcccaatga acagatgatg
      961 gaccattttc cagacccaca ttttttaaat gaacggtata ttgctttaaa tgagcagacc
     1021 gttcttttag ggatgaatgg ctggtacgac tatcagtttt ccgaattgaa agattacgag
     1081 gcaatcgtac gaatgaagcg tttgtattgg tatgatcggt tcatccagcg tgggaaaaca
     1141 gatctcgagg tcaatgcaga aatgcttgca gctgcaaaaa atttgctaga ccagctggaa
     1201 gcaaaaaaac ttgaggtgat tttatccact catttcgttc ctaaacgggc atttatcatg
     1261 tatcaatctg ctccttatga gcgttggaac aaattaaatg cgtttttagg atcagaatca
     1321 ttcggaaaat tactagatca ttactcaaat atcaaacaag tagtttttgg tcatacgcat
     1381 cggcggttcg aagatcagtt gatccatgga gcaatttata gttgtcgacc attcggttat
     1441 tattatgaat ggcaactgac tcgtgatttt gttttgaaag aacagttgtt agacagctat
     1501 gatcctatga aattacgtgt actcttgcgt gcccatcatc cggcctttca agcctatcaa
     1561 acacaacatt tgcaagagga atttgaacag gcgatgacaa tcgttccgta ttgagacagc
     1621 attagtaatg tgtaaaagaa aataccttgt aaaacataag gataagtaag agcagtagat
     1681 ccatttatcg tggatatgct gctttttttg tggaaaataa tcagcgaatg tttatttgat
     1741 cggatgattt gtaactcgca gagtactaga tgcaagcgtt tattcttttt ttgaacgata
     1801 atcacaaaaa aaaatataat atacattttt tatttaatta taattaatat tgattgaagt
     1861 ctaggcagtc aagtcacatt ttgatagata ggagggggac ttacgaatta ttttaaaggc
     1921 tatgacagct gtatttctag attgtgtttg catcaagttg caataaaaac tagaaatcaa
     1981 atcgggctga taatcattta taactaatcg atacatagga ccaaatatag gtctatgttc
     2041 ttttatttca taagtatcgt aaaacagaat tttgctatgg attaatccaa tcgactgata
     2101 tgtttagtaa ataaagaaag aggaatgtca atgatgaaaa aagaaatcgt attaacagca
     2161 acaacgatgt tattcagcat ggtagcaagt acgacttttg tttctgcaac tgaagtatac
     2221 ccaaaggaat ataacacaga aggaacgatt acatttgaag caggagatga gggtgtaact
     2281 cctcctgttg atccagagaa tcctgatccc aataaacctg tcgatccatc agatcctcca
     2341 agccctggaa caggaggggc attatcgatt gattatggat caaaattcaa atttgggact
     2401 caaaaaattt ctactgcgga taaaacgtat tatgcagctg ctgatgtgat gaacgatggg
     2461 tctagaaaac cgacatatgt ccaagtgaca gataggagag gtaccttatc tgggtggaaa
     2521 ttaagtgtct ctcaaccaga acagtttaaa actgccagtg gggatgaact agttggagca
     2581 cagctgaaat ttacgaaagg gcaggctgtt tctttggttg atccaacata tacgccgcaa
     2641 acggtgaatt ctgaattaac gttgacaccg ggaggaaaca atacgttagc aattaatgct
     2701 aaatcaggaa caggtgtggg gacttgggtc tatcgatttg gtgcaaatga aaatgaaaat
     2761 caagatgcgg tacagctttc ggtacccggt aaatctgtca agttagcgca acaatattcc
     2821 actaaattag tttggacatt agaagataca cctaacaact agtttactga aaagaactgt
     2881 taaaaataaa tacgtagtca tattgtcttg cgaggtaatc gagcaaaaat tgtcaaaggc
     2941 taggctaaat ttgtttggat acgaatagtt catctaggaa tttaacgatc aggaggaaaa
     3001 gatatattga aaaagaggag gatcgtgctc attttaagca gtctcttagt gactaatatc
     3061 tttccgatca tagggtactc tttggaattg aatcagttgg agcatggaaa tagaagagac
     3121 gaagaaagca aactcacttc gacattcgac agtttaatag aatccaacca gacacaagaa
     3181 agcagtgagg atttaagtat ttcgagtagt ggagagacca ctgacaacgt agaagctgag
     3241 ggttcggaca aacaaggact ggaagatgca ccaatttctg cggttgagct gcctgacgat
     3301 cccaatatta tttctatcga taaaattttt caaacaccta tcggtactag cacgtccata
     3361 ttggaaaatg ggaagttact gcagttgaac ccagcagaaa ggtctcaaag aggagctatt
     3421 tggtcaaata agaagattag tttactctcg gattttacat ttaaatctta tttatactta
     3481 ggaaatcaac gagatagagc gggagatggc atgaccttta cattgactgg cgatcctaga
     3541 atggctagta atcccagtca agttattgga tcgccaggta tgggaattgg ctcatattct
     3601 actcgttctg gccaacctta cattgcgaat gcgctctcga ttgagtttga tacgtataaa
     3661 aatagtggtt cttctgatcg aatggatcga gagataactg ctgataatag agggcatgga
     3721 catgtcgctt ttgtcacgcc taaaccaaat aataataatt attctggaga gcatactggc
     3781 gtgacggtag ctcctacatt tctttctaat ggcacatggc gcttgttaat aattaaatgg
     3841 gatgcggagc aaagaagtct tacttatgat ttggaaggtg tcggtcgctc ttctcggatt
     3901 atacctgatc tcattaggca gtttggttct acagaagtaa attgggggtt tacttcttca
     3961 acaggtactt tttttcaaga aaatgctgtc gctgtcacgc gacttccatc gaatgtcaca
     4021 tcaacagctg atgtaaaagt caacgatagt gattatgggg ccatcgctga agctggagga
     4081 aacgataaga taactatcag aaatacattg aaggtcgagg gggattttct tgaatataag
     4141 aaaatgcaga ctagtatcga cctcccacaa gaattaacta ttcccgagca tatcttgatc
     4201 aatggaaatc aaattgatgc caaagatatc ttgataaccg gaaatcgagt cacgctaaat
     4261 ctgacagatt attttattgc tggagatacg ttaataatcg aattggagac aactttgcag
     4321 gaagtaattc ctgaaaaagt actcactatg cattttgaat accttgaaaa cgagaatttg
     4381 attgagcaat cgaatgaaat aaacctaaag atcgcaaagc tgaaggagat agatatccat
     4441 gtttattata aagataaaga cagtcagatt gatattgctg aaatgaaaac aatcactggg
     4501 aaaataggag agaagtataa agaaactcct attgatattg aagggtatgt ctttgactcg
     4561 gattcagcga atacagaagg catcttctcc gaaaatacag aggatatcta tttttattac
     4621 agaaaaggca aactttatct ttcaactgct cctcaatatg tcaattttgg aaaacataaa
     4681 atatccagta gaccattaag tgaattcgga cagttttcag gtggattgaa aattatagat
     4741 gaacgggctt ttggaagttg gaaattacaa ttgaaacaag agaaagttct tacaaatgga
     4801 gattttgagc ttccagaagc tctttccttt gttacctctg aaaatacaac ggttataggg
     4861 acatccgctg ttacgatttt cgaaagtgat caaaagggtg aaagcgattt gtcctctctt
     4921 ttagattcta cagctcatcg tgggatcaga atagatattc ctgtagaaaa ccaaagaatc
     4981 ggaacctttg aggggaaact atcttggata cttgcagatg tcccaggaaa ttaacaggaa
     5041 gagaagaata taacaaaatt attgagtttc aagaagggca caggtaccat aggctcttgt
     5101 gtcccacaga gacaagatat tgttatagtc ttctcttaca tatgattaaa ggagcgattt
     5161 tcttgagacc aaaacaacaa ttatttataa cactcctagt tattttaggg gcacttttta
     5221 acaatatatc agtgtcagct agtgcattta atttttcagt gacgccgata acttcagaga
     5281 atcaaatcga caagagaaaa acttacttcg atcttcaact tgatccggat caggaagtag
     5341 aagtaaaagc ggaattgaga aatgatacag aaaaagaagt gaaaatcgat atttctgtga
     5401 atagcgcaac caccaattca aatgtgatgg ttgaatacgg aaaaaacgag attgaaaaag
     5461 acatgagcct gatctttgat ctggtagatt atgtgagcta tccacagata gtgacgctaa
     5521 aacctaaaag tgtccaaacc gttgcttttc atgtcaggat gccgaatgag cgatttgatg
     5581 gtgtattggc tggtgggatc acattccaag aaatccagac ggaaaaggac caaacagaaa
     5641 ctaaggatca aagcttatcg attgagaatg aatataccta tattattgct ttgttgatgc
     5701 gacagacact gaacgaagtt gctccgaacc ttactcttca tgaagttaaa ccagatcaaa
     5761 tcaatgcaag aaatgtcatc ttagcaaacg ttcaaaatga tcaaaaaact tacatcaatc
     5821 aagtaattat tgaaacaaaa attacaaaaa aagggcattc taaagtttta tatcgagaag
     5881 aaaaagaagc gttgcagatt gctccgaata caaatttttc ttttccaact gctttaaatg
     5941 gtcaaccgct aaccccaggt gaatatcacc ttacaatgac tgttttagga aatgaaaatg
     6001 aaaatggaaa attttcgaga aaaaaaggaa atactacgat caactatacc aatcaatggg
     6061 tatttgaaaa agattttaca atagacggaa aagtagccaa ggaattgaac acgacggatg
     6121 ttacgattaa aaaagacaat aattggattt atatcttagt agcttcactt ttcttattgt
     6181 ttattttatt atgcatactt ttgtttgttt tgagaaaaaa agaagagaaa gaaaagtaag
     6241 gtta
//
LOCUS       DADVXB010000143         6201 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.149, whole genome shotgun sequence.
ACCESSION   DADVXB010000143 DADVXB010000000
VERSION     DADVXB010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.149"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..262
                     /locus_tag="KB902_002382"
     CDS             <1..262
                     /locus_tag="KB902_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6809159.1"
                     /translation="LAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLN
                     PGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            507..1532
                     /locus_tag="KB902_002383"
     CDS             507..1532
                     /locus_tag="KB902_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6809160.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLRIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            1826..2935
                     /locus_tag="KB902_002384"
     CDS             1826..2935
                     /locus_tag="KB902_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6809161.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASANTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            3018..3914
                     /locus_tag="KB902_002385"
                     /pseudo
     CDS             3018..3914
                     /locus_tag="KB902_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            3930..4754
                     /locus_tag="KB902_002386"
     CDS             3930..4754
                     /locus_tag="KB902_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6809162.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINIFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGGKL"
     gene            4786..6096
                     /locus_tag="KB902_002387"
     CDS             4786..6096
                     /locus_tag="KB902_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBB6809163.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSRAYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
BASE COUNT         2131 a          905 c         1236 g         1929 t
ORIGIN      
        1 tttagcggct aaattagtaa aatttttaaa aaataagaat aaacgagtga tggaacaatt
       61 atcgattatt ggatttgatg atattacttt tgcagaatta atggatcctg cgttgacaac
      121 aatacgacta aatccaggta acaagggggc gattgctttt caccaactga ttggactggc
      181 caaacaagaa gaaataaaaa atcaagtact actattagag ggagaattga tttctcgaga
      241 ctctgttcac aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa caataaaata
      301 tccgaacgat agagagaatg aactgtgatc tagcagttcc tcgtcggaaa ttcactagaa
      361 ttagcattat ttactctaaa ttgttcggat attttttctt gtttttaatt atgattacag
      421 tgcctatttt taacgaaatt tgcttatttt caaaatgtat gattatattt tagtaaacac
      481 tttcaaatat gaaaagagga gctattatgg taggaattag ggatgttgca aaacgggcgg
      541 gtgtgtccat tgcaacagta tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg
      601 atgaaaccaa acgaaagatt gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc
      661 ccgttgcaaa aaatttaaca aatattgcat taataacgac agtttctgaa gtagatgagt
      721 tggaagatcc ctattttcga acgattcgca gagggattca agtcgaagca gaacaaagca
      781 aagtcaattt gaagaaaatt attcgtttgt cagaaacacc gttggagcaa gatgatttgc
      841 taaaatgtca aggtgtgttg attattgggc aggtgctatc ttctgtgatt gaagaagtat
      901 cagcaattaa ttcgaatgtc gtagtgattg atgaccctag tattgaagct gaagtagatg
      961 cagtttatac tgatttaaca aaagcaacga atcagcattt agatcgattg tataaaaaag
     1021 gacaccgaaa cattgcgttt atcggaggag gacgtgttcg tttagatagc caaggaaata
     1081 aacacgtgtc agatgatgat tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag
     1141 gattagaaaa atatagtcaa atttatttag aaggctggac cacacttgac ggaatgcagg
     1201 cagcagattt acttttgaaa aaacatgcta aagataagtt gccgactgct atcatggtag
     1261 gaaatgatcc tattgctgtg ggggtttatc gttcacttca aaaaaatggt ctacgtattc
     1321 cagaagatat ttcgattgtg agttttgata atattgaagt tgctgaattt ttaacacctg
     1381 cattaaatac ggtgaatgtg aatacagaag aaattggaaa actagcagtt cgcatggtta
     1441 atgaacgaat aaaagaagtt agaaatgttt cgatcaaagt gattgtttct aataatatta
     1501 ttgttagaga aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa aaggatgttt
     1561 acttttttgt ttactaatat ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt
     1621 atggtgttgt taacaaaaag aaaacgcatt caaaacagga ggaattaaga tgaaacattt
     1681 caaaaaaata gctttaacag ggatagctgt tttaactggg acattactcg cagcatgtgg
     1741 tgggggagat agtaattcta aagacgggca agtaacttta agctatgcga gttgagatac
     1801 tgaccaagct ccaggactaa gaaaaatatt agatgaattt gaaaaacaaa atcctgatat
     1861 caaagtagaa atggagacaa cgccttggga tcaatattgg gttaaattag aagctgcaac
     1921 aacgggaggt aatatgccag atgtagtaac catgcactct agcgaatcct ataaatatat
     1981 gtcacagaat gctttgatgg gacttgatga tgttatcaaa gaaaatgata ttgacatggg
     2041 aaactttact gaaggaattg ctgatttcta tacgcttgaa gacgaactat acgcaatccc
     2101 taaagatgct tctgtagtgg ggctatggta caacaaagaa ttatttgata atgcaggtgt
     2161 cgattatcca gatgaaacat ggacatggga aacactcaga caagctgcaa ttgatttaac
     2221 agatgaatca aaaggcatct atggttttgc atcacatatt ggaacagaga ctggctactg
     2281 gccatttatt tatcaaaatg ggggagaagt atttgccgat gacaatacaa aatcaggttt
     2341 gaatacccca gaagcacaag aagctttagc tttttatcga gatattgcac ttgttgatca
     2401 tgcttcacca acaattacag aattacaaga tcctgataag ttaagtcgtt ttcaatcagg
     2461 tagattagca atgatgattg aaggaaactg gtttgcaccg ggatttttga aaaatgacta
     2521 tctagttgaa aatgttgctt ctgccgtgtt acctaaggga aaagttaatg caacaattac
     2581 aaatggactt ggttgggctg ccagtgcgaa tacaaaatac ccagaagaag tgaaaaaact
     2641 aatggcattt ttagctagtg aggacgccaa taaaatccaa gcggaaacgg gggcatcaat
     2701 cccagcacta aaaggctttg aagacgagtg ggctgcttct tcagatacaa ttgatttgag
     2761 tgcttttgga aaaatgttgg agtatggagt ccctcgtcca tacaataaag atggattacg
     2821 agctgaacaa gcagaagttc aaattattaa ccgtattctg tctggtgaag taactgttga
     2881 agatggaacc gctcaaattg aaaaagaagt caatgcgata ttgagcggaa attaaattag
     2941 ttaattatac aatatacagg cgaaaggatt ctatttcgtc tgtatattaa tggatgaata
     3001 ccaaaaaggg ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga
     3061 tatggggcta tatttttatt tttccaacgg cattaggatt aattttatta aatatatggc
     3121 cagcaattca aacagcaatt ttaagttttc aaaaaacggt agggttcggt gatactgaat
     3181 gggtcggatt aagaaattac caaaaaatgt ttgcagacgg tgaagttttt cagtctttat
     3241 taaacacatt aatttatgca gtggtttcga tacctagtat tgttgtatta tccttgttgg
     3301 tggcagtttt aatgaataga aaagttaaag gattgtcgat ttatcggaca atttattttc
     3361 taccagtcgt tgctgcacca tccgcagtcg caatgatttg gcgctggatg ttcaataatg
     3421 attatggact gattaataac atgttggcta aaataggtct cgatggacca gcatggttaa
     3481 cggatccatc gattgcgatt tattctatta tcattgtagg agtttggagt gctattggtt
     3541 ataacatggt gttattacta gccggcttat aagaaattcc taaagattat tatgaagcag
     3601 cggaaattga tggtgctagt ccaatccagc agtttttcaa cattacgtta ccattagtta
     3661 caccaacatt attttttgta gttgtaacaa cagttatcaa tgctttccaa gtatttgatg
     3721 ttatttttat gatgattact cctaatagta ccgccatgtt taaatcacaa tcattagcct
     3781 atttattcta taaacattca tttattttaa atgacaaggg atatggttcg gcaatcgtta
     3841 tgttcctttt agtgattata ttaattatta ctgcaattca aatgaagttg cagaaaaagt
     3901 gggtaaacta ttaaggaggc tatcaaatta tgaaaaataa atttttttca aatgcgccaa
     3961 tccatatcat gcttatttta ggtggtattg caatggcatt accttttatt tggatgattt
     4021 taacttcagg gaaaacgttg gttgaatcta cccaaattcc acctacaatt ttccctgaga
     4081 aatttcagct aagtaactat caacaagtac ttgatttatt accattcatg gctttttata
     4141 tcaatatatt tttaatggtt gttggacgag tgattggctc ggttttattt tcagcaatgg
     4201 ctgcatatgc ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc agcttagtac
     4261 ttattcaaat gatgattccc ggttccattt ttattactcc acagtattta ttagcacaaa
     4321 aattgggtat tttaaataca attccagcat taatattacc aggggtagtt agtgcgtttg
     4381 gtacgttttt attaagacaa tttttcttag gtttgcctga tgaattggag gaagcggcct
     4441 atttagaagg tgccaatatt tggacgatct ttttcaaaat tatgttgccg cttgctaaat
     4501 caggattggt tgcacttgga atattcacag cgttgtttgc atttaaagat ttaatgtggc
     4561 cattgattgt caatacttca attgataaga tgcctttagc tccgggatta gcaaacttac
     4621 aaggacaata tgccacgaac ttcccacaat taatggcagg ttcgttatta gcaatttggc
     4681 caatagttgt gatattcatc gttttccaaa gaaaattcat tgaaggaatt gctacaacag
     4741 gtggtaaatt ataaaactat taattagtga ttggagagta agtacatgac aaaaattaca
     4801 tttattggtg caggaagtac tatttttgca aaaaacgtat taggcgatgc gatgttaact
     4861 ccaagtctac aagatgcaca tattgcattg tacgatattg atgaaaaacg actaaaagaa
     4921 tcaaatttaa tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc tgatattgtt
     4981 tcttattatg atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa tgctattcaa
     5041 gtgggtggtt ataaaccttc aacagtgatt gattttgata ttcctaaaaa atatgggttg
     5101 cgacaaacta ttggtgacac catggggatt ggtgggattt ttagaaccct acggacacta
     5161 ccagtaatgt tagactttgc taaagaaatg gaagaagttt gtccaaatgc ttggttattg
     5221 aactatacaa atccgatggc gatgttaacc atgggtgttt taaaagcgac gagtattaag
     5281 actgttggtt tatgtcatag cgttcaagta tgcgtaccag aattgtttga gcatttagga
     5341 atagccgatc aatatgactt aaatgacttt caatggaaaa ttgcaggcat taatcatatg
     5401 gcattcttgt tggaaattac aaaaaatggg gaagatttct atccaacaat tcgtcagtta
     5461 gctgcagaaa aaccaaatcc acatccagat tctgtacgtt ttgaattgtt gaaacgtttt
     5521 ggttactata ttacagaatc aagtgaacac aatgcagaat accatccata ctttattaaa
     5581 tcaaaatacc cagaattgat tgacgaatta gggattccgt tggatgaata cttacgtcgt
     5641 tgtgaacaac aaattaatga ttgggaaagc atgcgagagg acattgtaaa taatggggag
     5701 ttaacacata cgagaagccg tgcatatgct tcatatatca tggattctat tacgacagga
     5761 actccgtcag tgattgcagg aaatgtctta aataaaggct taatcacaaa cttaccgaca
     5821 gatgtttgtg tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc
     5881 ggtgaattgc caacacaatt agctgcttta aatcggacga atatcaatgt tcaagaactg
     5941 acagtagaag ccgctttaac actagataaa tcaaaaattt atcaagcagc gtatttagat
     6001 ccacatctat catctgaatt gtctttaaca gatatcaaaa atttagtgga tgatttaatc
     6061 gaagcacatg gggactattt acctgaatat aattaaaaag aagctgaaag agtaaggaat
     6121 tttcaattcc ttactctttt cttagttaaa tttagtaaaa atattgacaa aacacttagt
     6181 aaacagttac attagtgtta a
//
LOCUS       DADVXB010000144         6173 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.150, whole genome shotgun sequence.
ACCESSION   DADVXB010000144 DADVXB010000000
VERSION     DADVXB010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.150"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            725..811
                     /locus_tag="KB902_002388"
     CDS             725..811
                     /locus_tag="KB902_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6809164.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="KB902_002389"
     CDS             complement(932..1621)
                     /locus_tag="KB902_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809165.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="KB902_002390"
     CDS             complement(1628..1906)
                     /locus_tag="KB902_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809166.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="KB902_002391"
     CDS             complement(1866..2780)
                     /locus_tag="KB902_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6809167.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="KB902_002392"
     CDS             complement(2762..3142)
                     /locus_tag="KB902_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6809168.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="KB902_002393"
     CDS             complement(3592..3879)
                     /locus_tag="KB902_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6809169.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="KB902_002394"
     CDS             complement(3899..4123)
                     /locus_tag="KB902_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBB6809170.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="KB902_002395"
     CDS             complement(4578..4748)
                     /locus_tag="KB902_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809171.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="KB902_002396"
     CDS             complement(4763..5296)
                     /locus_tag="KB902_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6809172.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="KB902_002397"
     CDS             complement(5317..6159)
                     /locus_tag="KB902_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6809173.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DADVXB010000145         6133 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.151, whole genome shotgun sequence.
ACCESSION   DADVXB010000145 DADVXB010000000
VERSION     DADVXB010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.151"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..200)
                     /locus_tag="KB902_002398"
     CDS             complement(<1..200)
                     /locus_tag="KB902_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809174.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIR"
     gene            complement(197..400)
                     /locus_tag="KB902_002399"
     CDS             complement(197..400)
                     /locus_tag="KB902_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6809175.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            complement(397..708)
                     /locus_tag="KB902_002400"
     CDS             complement(397..708)
                     /locus_tag="KB902_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6809176.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEEA
                     E"
     gene            complement(885..1199)
                     /locus_tag="KB902_002401"
     CDS             complement(885..1199)
                     /locus_tag="KB902_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBB6809177.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            complement(1338..2153)
                     /locus_tag="KB902_002402"
     CDS             complement(1338..2153)
                     /locus_tag="KB902_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6809178.1"
                     /translation="MNENKLIKLGAAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            complement(2210..2671)
                     /locus_tag="KB902_002403"
     CDS             complement(2210..2671)
                     /locus_tag="KB902_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809179.1"
                     /translation="MRTVIQGKEITVTIKSERELDTQEIIAAHQLATGNFEALFIKED
                     SKTSNNNKEVKTKSVEKDIPKWVQVEITCPVCTHESRTTTKYGNVFTKCPSCKTPLYN
                     KYATGIAGEHDKAGNYYYAQEVLRPRNGGLTHEEQELLNAMSQAVTSENNG"
     gene            complement(2671..2970)
                     /locus_tag="KB902_002404"
     CDS             complement(2671..2970)
                     /locus_tag="KB902_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809180.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRRIAIWHGDRILVTGTAEQLSEITGLSKNTIWDRASSLWIDSKGRQFRYVEEK"
     gene            complement(2973..3134)
                     /locus_tag="KB902_002405"
     CDS             complement(2973..3134)
                     /locus_tag="KB902_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6809181.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIVNL
                     RREIRRLEE"
     gene            complement(3149..3508)
                     /locus_tag="KB902_002406"
     CDS             complement(3149..3508)
                     /locus_tag="KB902_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBB6809182.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(3505..4356)
                     /locus_tag="KB902_002407"
     CDS             complement(3505..4356)
                     /locus_tag="KB902_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6809183.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPSHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(4373..5203)
                     /locus_tag="KB902_002408"
     CDS             complement(4373..5203)
                     /locus_tag="KB902_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBB6809184.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLIEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            complement(5206..5892)
                     /locus_tag="KB902_002409"
     CDS             complement(5206..5892)
                     /locus_tag="KB902_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809185.1"
                     /translation="MFKPLIDSYSAVLRRFKGNQIVARINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GVDIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            complement(5898..>6133)
                     /locus_tag="KB902_002410"
     CDS             complement(5898..>6133)
                     /locus_tag="KB902_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6809186.1"
                     /translation="DVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASI
                     TADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
BASE COUNT         1485 a         1359 c          949 g         2340 t
ORIGIN      
        1 atgcgaatga tcgctgagtg attatagacg tgttctacat atccacgaaa tggataaatg
       61 aactcctctg cttcacagcg gaccatgtca ccgactttga cttttggttt cttacgtgtt
      121 ttaggattct ttgtcggcat atctagcatt aaaccgccga taccgtgact gctagcgtaa
      181 aatccgtctt ttagtttcat tctttttcct cccatttacg atcatcactt aatatcgaaa
      241 ttccaaactt acgaatagca tcacttgcat cagcaacaca ctgacttgcc actttatatg
      301 tttcttctgc tgaaattcca tattcttttt caaactttgt ctttagtaca ttcagttcct
      361 gttttcttag ttttgttatt ctgcgatgtc tgttgttcat tccgcttcct ccaaatcact
      421 cgacttcacg aatacaccat ctaccatttt ccctgtgcgt cctttgattt cgttgtatgc
      481 ttggttcaga cactcgtaca aatccatatc attttgcata gctaaaataa tcaaggttac
      541 tactacgtct ccaattccgt ctcttaaacc atgttcatct tttctagcta gagaagcggc
      601 aacttcccca atctcttcga tcgtttttaa catttgcttg ctggaatcag cttgatccaa
      661 tcccttatct ttagcccact gctctacttt tgtgattagt tcgtccatta ttcattctcc
      721 tttatatatt taagttggat aatacaactt gtaacaaatg aagctaatgt taaaattgtg
      781 ccgattggtg ttaaaaaacc gctttttatc gtattaatta atatagctac aaatatcgtt
      841 atatagaata aaaagtgaat tgacgctaac attgaattaa acatctagtc ctcctcgaaa
      901 tactcattca gtatctctct atacttttct acaaacttaa aacgatcttg atgaagtttc
      961 ttgctccaat ttgtttgccg atccagctca cgcatctgat cgaacccttt ttgaatttcg
     1021 ttgtaataaa attcaatgtt tgctgctgcc ttccaatgcc tgctacttcg cactcctgct
     1081 cctgtttcag ccatttccaa cttaactaat tccgctcgtt cttttgcttt tttatctttc
     1141 tgaatctttg ccatgatttt cttgaggatg atatcactgt attgtgtaat gagatccatt
     1201 atttctcctc ctaaaatttc atttcatcgt tgttgtcatc ttctttgtca tcagtttggg
     1261 aaaggagcgc atacacgaga tatgctgctc ctactaaacc taagaacaag agaattttag
     1321 ccataaagaa tcccatatta tttgcctgct tcatccgtaa ctacagtatc tgctccattt
     1381 actgttaccc atccatgctt tttgcgagct tgagcttctt cataacgaat caaattgtct
     1441 gttactgatt cggcgacttt gcgattagat tctgcctctg cttctgcagc ttttgttttc
     1501 ttgtaagctt cactatcagc ttgagttttt gcagtttctg catctagctt cgctttttca
     1561 ttttcttgac cagctcgaat gatcgcatcg attgattttt gtgtttcttt atcgacatct
     1621 ggaacaccaa gtgttacgtc ttcgacttca aaccctttag attcaactga tttagcaaag
     1681 ttcgttaata cctcagcttc aactttagag gaatctcctg aaaggacatc aagcagacta
     1741 tatttcgcat aaacttcacg agcgaccttt tgaagcttag attttaacca tccactttcg
     1801 atatcttccg aagtgatatt cccaaattcc ttgtacattt ttgctgcttt agttgaatca
     1861 actttgtagt catatttgat atcaatcgtt gtctttttgc cgtcgcttgt agatactgaa
     1921 atattttttg attggatagt ttgcaagcga attggatatt ggatcacttt gtcaatccct
     1981 acaaatttca caccttgcgt cagtgcttca tctttgatac cgccgttcat tgaatagcgc
     2041 acacccacat atccattatc gattttttcg aagaacttaa atcctccgat aactccaata
     2101 cctacgatta ctgctcctgc tgcacccaat ttgattaatt tgttttcgtt catttttctt
     2161 cctccaaatt tcttatttcc ccaaatattt gcttgttaac tcattggttt tatccattgt
     2221 tttcactagt cactgcctgg ctcattgcat ttaatagttc ttgttcttca tgagtcagtc
     2281 ccccattacg aggacgtaaa acttcctgag cataatagta gttgcctgct ttatcatgtt
     2341 caccagcaat tcctgttgca tatttgttat acaaaggtgt cttacagctc ggacattttg
     2401 taaatacgtt gccgtattta gttgttgttc tgctttcatg agtacatacg gggcatgtga
     2461 tttctacttg gacccacttc ggaatatctt tttctacaga tttcgttttt acttctttgt
     2521 tgttgttgga tgttttgcta tcttctttga taaacaaagc ctcaaaattc cctgtagcca
     2581 attggtgtgc cgcaattatt tcttgtgtat ctagttctcg ttctgactta attgttactg
     2641 tgatttcttt tccttgaatg accgttctca ttatttctcc tccacatacc taaactgtcg
     2701 tccttttgaa tcaatccata agctactagc tctatcccag atggtgtttt tgctcagacc
     2761 agtaatttca gataactgtt cagcagtacc tgttactaga attcggtcac catgccagat
     2821 tgcaattctt ctcggcgttt tccgtttagg cttttcagtc cacattgatt taccgagctt
     2881 ttggacttct gcaactattt ctttgtcttc ttgccaattc tcagaatgtg tcagttcaat
     2941 gattcgtttc attgctgctt tcttatccac gctcattcct ccaatctacg aatttccctt
     3001 cttaaattca ctatgtgtaa atcgattgcc ttccttgccg tttcattgac catcactgcc
     3061 tttgttcgtt ccagatcgtc aatttcacgt tgaatgcttc gaatacgcat ttgaatcact
     3121 tcttctgttg tcatgatgga ccacctcgtt aaaaacgctc ttccttgaac gtattccgat
     3181 attttttggc taatatcaac ggcacttgat attgatgaca gaacaacttt gccttgatct
     3241 taaagtcttt tgtctgcatt cctttgacat ctacgacttt gacaagtttg ccgtttttat
     3301 aaaatgtgaa gtcaggaata tactcgatct tgcgatactt ctttccgtct agttcaaatt
     3361 tcggcatcag ctcaaatctt tcctgaagtt ttactttcca gccgttcgct tcagcttgcc
     3421 acaaggctag atcgtaatac tctgcttccg cgatagaatc aaacttgata cctcgatgaa
     3481 cagttttttt attacggtat ttattcatgc gatactacct ttcactggtt ttatgcgctt
     3541 gtctgctgtt tgttggaatt tcagcgcata accttctgaa ttcttaaata tcctagaaac
     3601 aattctttcg ccgtaggctt ctcttagttc aggaccagat aagtttgttg tgatgatcgt
     3661 tgccttgttc tgtctggctt ctaagagcgt gtttaacgtg ttgtttgtaa actgcctact
     3721 attcgatacc ccgctaccta attcagctcc aatatcgtca aaaaccacca aatcagttgt
     3781 tttgatatcg gctataagcg atccttcaat ttcttttctc agttcagcat tgttataaga
     3841 aaactttatt tgctctaata actcttgata gcttataaaa agtattttct tgtcataatt
     3901 tgagcgctca agtatttccc aagctgtcgc cattgataag tggctttttc cgcttcctga
     3961 tttccctgat agaatgaaat gtgaaggatg attcagtagg acatcattta catagctttt
     4021 agctctttct aaagcaattt tcgtttcttg gtccactacg tgataattct ccattttgca
     4081 tttaaacaaa gttttatctg ttaaaaccga accattttga aaaaaactca acgctcgtgc
     4141 ttttaagctg tcgttatata tccgttcggt ctgtatatcc tctttcacac gtaacgcttt
     4201 ataaccacaa ctcatgcatg ttggtttaca acgttctgaa ccatccttat ttttagctcg
     4261 ccaactatac aaaggttcgc tacattctgg acattttccg ctttgcacta atactcttct
     4321 tattagtttc tccatagcat ttgctaggct ttccatgtga tgcatctcct ttttaaattg
     4381 gcaagtcgtc atattcacta ggattgctgt actgtagttt ttgactttgc tttttatgat
     4441 ttttcttgtc tgctttgatt tcgaatttga gcttctcaaa tttttctctc aatttcttag
     4501 cacttctaat atttccaaac caaaattcat ttgtaggtag ccaattgatc acatactcaa
     4561 tcgcttctat agacgctttg tctctttctt caatcaacct gattgtgtct gcccattttt
     4621 cgatatctac tttattcatt tcttttggaa aatcttcagt taaattactt tgcaattttt
     4681 tagcaaggcg taagtgttcg tcagaatact tacctttctt ttcttcttta tctatatctt
     4741 tatcttcttc tatatcttta tctgtaccgt cacgtgacgt cacgctaacg tcattttcca
     4801 atttgagacg ttcctgtctc tttctttccc tgtatttacg gtttctttca gcatttttta
     4861 gccttacttt atccataccc tcgatatttt gatgtttttc ccaattactg atggcaatta
     4921 gtccatcact gcttagatca atcatgttga aatttgccaa tgtagttagc gctaagcgaa
     4981 ccgtatttac gtttttgcca aacaatgtag caagcatttc ttcggtataa ggcatgttcc
     5041 tctggatata tatcagacca tcgtcgttag tctttcctgc taaaactagt aatcgaatcc
     5101 atataacgat gatggcatcc gactcaggaa cagcttgaat taatcgtatt ttttcatcgt
     5161 caaacatagt agttttaagt ttgatccaac ttatctcagc caaatttatc ctcctattct
     5221 taacttttta atcgtttcat gacttaactt gattcctttg atttgatatt tatttttgaa
     5281 attgatcaca cctattttgt gtttctctgt gtgatggatt ctgcagagtg ctgcaaatgt
     5341 gtactctgaa tgatcaactt ctttgcgctt tcgtcttcct agcgctttgt caaagtgatc
     5401 gatgtcaact cctgttttgc cacagatgca gcagactctt tttgtaatgc atttgtagaa
     5461 gtaatattct tgattcgctg gtaaaatctc atagccttct ttgaaaggaa tatgatgttc
     5521 aaagatgaaa tctaagatga tatttgctaa gacattagca tcactcacag ttgtattcga
     5581 ttcgtctttg aggcttattt cgcgccctgt gacaccttca aaacggaagt agaagaattc
     5641 cttccagaag tccgttggca tgcctgtatc gatgaaaata tcgcctatga gcgcatagat
     5701 gaagtttctt tgctgtactg tgaaccgacg tggatcaata aagcgaattt caatgactcg
     5761 atcgccatcg tagccgtcat acatcgtctt caatcgctcg atattcactt cttcattgat
     5821 tcttgccact atctggttgc ctttgaatct tcttagtacc gccgagtatg agtctattaa
     5881 cggtttaaac attcatatca cttctctttt gtttcttctc tgtactgatc ttcaagccaa
     5941 ttaacgcctc gttttagaat gcccaagtct ctcttggtcc atttactgtc atcagcggtt
     6001 atggaagctg catcagtcaa tgcaacaatt gcttcatcaa ttgatttttc gtacttgtta
     6061 gcaaccagtt gtaaagcatc caagaatagc tttttgcttc tttgagtagc tggttcaagc
     6121 atcgagacat ctt
//
LOCUS       DADVXB010000146         6110 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.152, whole genome shotgun sequence.
ACCESSION   DADVXB010000146 DADVXB010000000
VERSION     DADVXB010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.152"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(322..807)
                     /locus_tag="KB902_002411"
     CDS             complement(322..807)
                     /locus_tag="KB902_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809187.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(946..1161)
                     /locus_tag="KB902_002412"
     CDS             complement(946..1161)
                     /locus_tag="KB902_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBB6809188.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1385..2185
                     /locus_tag="KB902_002413"
     CDS             1385..2185
                     /locus_tag="KB902_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6809189.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2204..4072
                     /locus_tag="KB902_002414"
     CDS             2204..4072
                     /locus_tag="KB902_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6809190.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            4065..4556
                     /locus_tag="KB902_002415"
     CDS             4065..4556
                     /locus_tag="KB902_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBB6809191.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4544..5098
                     /gene="srlA"
                     /locus_tag="KB902_002416"
     CDS             4544..5098
                     /gene="srlA"
                     /locus_tag="KB902_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBB6809192.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5116..>6110
                     /locus_tag="KB902_002417"
     CDS             5116..>6110
                     /locus_tag="KB902_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBB6809193.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2161 a          968 c         1224 g         1757 t
ORIGIN      
        1 tttgaaaaag ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa
       61 ttcttctatc caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt
      121 aactcagttg accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa
      181 gtgagtatat tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat
      241 ttatactccg tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta
      301 aatccgtata atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga
      361 tccttcgggt gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg
      421 tttgctggaa gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat
      481 atcgtcactt tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt
      541 ttctaatgga agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa
      601 cgactgaata cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat
      661 ggaagtagta gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga
      721 ttctttaaca gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa
      781 caagcctgcg taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc
      841 agtatatcac ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa
      901 gggaaggttc atgaagataa taactttttt aataattata gctttctaat atctttcatc
      961 aacttttcta gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac
     1021 gatataaatg atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc
     1081 aagttcgaac aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc
     1141 aatagcatct aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat
     1201 caaaaagaga aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat
     1261 gaaaattttt tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg
     1321 tcttaatttt ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc
     1381 acatatgtcg gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc
     1441 aggaattgga agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt
     1501 tgatgtaact gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc
     1561 ttctaaaacg gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga
     1621 tggtctagtc aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc
     1681 aaaaagcaag tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa
     1741 aagtgtatat ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt
     1801 gatcgtgaat ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc
     1861 tgctacaaaa gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag
     1921 gaatgttcgt gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca
     1981 agaatatgaa gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg
     2041 ttacagtcga acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga
     2101 tctagtctgc tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat
     2161 ttcaggaggt aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag
     2221 atggtaccaa ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca
     2281 aaaagaaatc aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga
     2341 aattgccggt attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga
     2401 ttttgatttt tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc
     2461 ggcatccaaa agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg
     2521 tatggatgat ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa
     2581 gacattaaaa gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg
     2641 actaagaata ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc
     2701 ctacttttca gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt
     2761 tcagaagaag acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat
     2821 ttctttgaat agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg
     2881 gtgttttgaa tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga
     2941 actaactttg agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac
     3001 aagtataacg atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat
     3061 gatgcgtatt cgacgattag atctcattga tctggatgag tccttcttat atcaagagat
     3121 gaaacagcac ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt
     3181 attttatggt gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat
     3241 acaagcatta gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac
     3301 gttgtatttg gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc
     3361 cattgttcat acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat
     3421 attggggagg gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct
     3481 aaacaaatat ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc
     3541 ggtgatccat ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc
     3601 aaaaaaaaag cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga
     3661 aaaaaagacg tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta
     3721 tgtggatgaa gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt
     3781 taacaaagaa tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc
     3841 agtagggcta ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt
     3901 atttgccata cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga
     3961 tatcctattt gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca
     4021 agaatcattt ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc
     4081 tattcatagt tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac
     4141 taaagcattt caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta
     4201 aacgacctgg gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc
     4261 aagttttaga agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac
     4321 ctgtctatgc gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg
     4381 aagatcgttt gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg
     4441 caggaaatga aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc
     4501 ggatatggaa aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa
     4561 atttgctgag ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat
     4621 gacaggaatc gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt
     4681 tttaggtgaa gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg
     4741 ttaccttgtg ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat
     4801 ggctcgtttc cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg
     4861 tcatacgagc aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg
     4921 gattgctcaa gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt
     4981 gcttgtggga ctgctgatga actttattgg tggttggata actgatttta ctactggatt
     5041 tgtatgcaga cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag
     5101 aaaggagagt tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga
     5161 ggtcctttga ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga
     5221 ggtgagaggc caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat
     5281 gggttcaaaa catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg
     5341 actcttagat gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca
     5401 ggaaaaagtg gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg
     5461 ttagaacaaa tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca
     5521 tctccagata aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag
     5581 cagcaaaact ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat
     5641 caatcagcaa gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc
     5701 gtttcccttt tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt
     5761 atggcacctt tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg
     5821 ccatttttat ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg
     5881 atcggtgtag agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt
     5941 gctatcaata ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca
     6001 aaagctgaga cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc
     6061 atcccacgag ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DADVXB010000147         6056 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.153, whole genome shotgun sequence.
ACCESSION   DADVXB010000147 DADVXB010000000
VERSION     DADVXB010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.153"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1413)
                     /locus_tag="KB902_002418"
     CDS             complement(<1..1413)
                     /locus_tag="KB902_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6809194.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(1424..2092)
                     /locus_tag="KB902_002419"
     CDS             complement(1424..2092)
                     /locus_tag="KB902_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6809195.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2223..2807)
                     /locus_tag="KB902_002420"
     CDS             complement(2223..2807)
                     /locus_tag="KB902_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6809196.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(3142..3372)
                     /locus_tag="KB902_002421"
     CDS             complement(3142..3372)
                     /locus_tag="KB902_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBB6809197.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(3387..4334)
                     /locus_tag="KB902_002422"
     CDS             complement(3387..4334)
                     /locus_tag="KB902_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6809198.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(4334..5176)
                     /locus_tag="KB902_002423"
     CDS             complement(4334..5176)
                     /locus_tag="KB902_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6809199.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(5309..6034)
                     /locus_tag="KB902_002424"
     CDS             complement(5309..6034)
                     /locus_tag="KB902_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6809200.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
BASE COUNT         2021 a         1093 c          747 g         2195 t
ORIGIN      
        1 tttcgttatg tcattaaaaa tctgttctat caaagttgaa tcttctactc taagttttat
       61 atcttttttt attccaccat tttttaaata aataattcta ttgcatgttt tataaagaaa
      121 ttccggatca tgagtggcta taactactgc acccttttct tttaagtctt taataaggtc
      181 agcaatcctt tccatattaa tataatccaa cccacttgta ggttcatcaa atagaaataa
      241 attagttttt gacaatgaag ctatagaaac caataatctt tgtttttctc caccggataa
      301 atcaaacggt aattgatctt tcattttata aagttccatt ttttttaaaa ttttttcttg
      361 ctgatcttta ctaactattt cattccccag ggctaactcg ctcctcactg attctgtgaa
      421 aaattggtaa tccatttctt gcattactaa aaacggcgat gacaaatttt ttttattttc
      481 gattatcttt cctttggtag ggcgaataat cttcatgagt attcttagta aggttgtttt
      541 ccccacaccg tttttcccta ccaaaccaat aacatctcca actttgacat caaaatttat
      601 gtcttttaga atattttcat aagtaatttc ttcaactttt aatacatctg cacttacctt
      661 ttcgatatag ggaacttcaa tcgaactatt aaaaatgtca aatttcctta atgcgttatt
      721 gttttcagtt tttaacaact gaatagttgt agtttttaca gttctatttt taacaaatag
      781 aacttgatca attaattctt tcaaatagta aaaacgatgt tcagctataa caatagtaaa
      841 tcctttattt tttaaatcac aaagtaagtc agcaagtttc ttagtcgctt tgaagtccaa
      901 atttgaagac ggttcatcca atataattaa tttagagttt agcgataaac tacatccaat
      961 agaaattttc tgccgttcac cacttgatag cgaaaaaatg tttttatcta atatatttga
     1021 aagatctaat aattcagcta attcattgat tcttttatcc atatgctctt ttgtaaatcc
     1081 aaagttttcc atcgaaaata ctaactcact cgttgtattt gttgtaaaga attgtcctct
     1141 aggatcttga cttacgtagc caatattttt tgatatactt tcttgtgtta aggattgtag
     1201 cgagttattt tcaaataaaa tttccccaac caattttccg tcataaagtc ttggaataag
     1261 tccattcatt aactttaata gtgtggattt cccactccca gaagaaccag taatcaatgt
     1321 aagactacct ttttttattg aaaaattaag gtcaacaagc gcttgttcct taacatcctt
     1381 atatgaaaaa gaaacattgt taaattcaaa caattctttc acctcaaatc aaaatactta
     1441 agaaaaaaat agtaacggaa aacaggatga tatagtctaa taagctcatg tttgttttat
     1501 agtaagaact tcttttcaca ggagattcta tcccctttgt tattgcatta gcggtcattt
     1561 cttcagcaat catagttgca cgtataagaa cgggaactaa cagaaattcc aaatattgca
     1621 gaggctgaaa aaaagacaag cgaatgtttc tcatttttaa agattcttta atcattctta
     1681 tttcagaacg ataagtcgga aagaatctga tcactactgt aatacttaac attatttttt
     1741 tcggtaaatg tattttttct aaagaggata ataattcatt gctagtatag acactaacca
     1801 acaaccatga gatcattacg accggcaaca ttcgaaatac aatatataag gatgtcccaa
     1861 aaaatatagt aaaaaactct atcttgatag catcaataat tttcattact aaaaacagaa
     1921 ctgaataaat caagatgaaa taaatacatg tctttatttt acgaaacatc aatactaaaa
     1981 ctgtagcaat aatgaaacac cccacttgaa atatatttcc ctttcctaaa aaaataatga
     2041 ccggaaaaaa aatatttaaa gtaatcaagg ttaacggatt gatttttgac actctttcac
     2101 ctccaaaaaa taagatcgca ctgttatctt aagctgataa aaatgcaccg ttattcagat
     2161 aacagtgcga tcttatcaaa aagcataact gagaacaatt ctcaatgcaa gctttttttt
     2221 aattaactca gtaattcaat ccacccagga acagaaaatt gatacaatct tctggttaat
     2281 agcatagtct tttcttttga atagctatgc ttcaatatat catagaatgt agcgtagaat
     2341 gagtaaatgt agaagtggat ttcttcttca ttaaagacta aattttgatt gatcattccg
     2401 atagtcttta acttatctag acaacagact gtcttttttg tcacaaatga tgtaattttt
     2461 tcaacaatat cttgatattt ggttccagct gattggaata aaaccaaatc gaatatacgt
     2521 ttattctcaa aaatataatt aataaatgga tctaattcat tgaagttctc tctccaactt
     2581 ttctctatat ctatattttc taagtttaag aggtatttgg taaactcttc attatacata
     2641 ttaataagcg cattaatatg cggctgaata atttcttcaa ataacgcttc cttagaagta
     2701 aaatgtttat aaaaagcacc cgtagttacg cctgcggtca agcacagttg ccttatctta
     2761 gtttgctgaa atcctacttt ttcaaaatgg cttagtccac tttctattaa tttttggtga
     2821 gttgtaatat aatctctggt ttctatgggt acttcctcct aataagatga attaactata
     2881 ttatcttaca caggacttga agtttcaatc gttaacgtct attactgaac tcattcctta
     2941 gagctaaact aatgagaaag agcaaaataa ctgatacaaa aagcaatcct acaagaatta
     3001 atagactcat ctaaatcatt caccttttct aaaataatcc gagaaagatt taaaaaaatt
     3061 atatccagct attaggataa gtcctatcat aatcactcca atagccattt tcttatcctc
     3121 cctaaaaata aagcctttta cttaaaacct ttttttgtaa tcgtcaataa attttttccc
     3181 tttatcagtt aattgaaatc ctatatctaa atagtcctca tatctaagtt tagtcagcat
     3241 ctcacttaca gatgctggac taacacttag aacttttgct aaatcattat tttttaattt
     3301 cttttttctt tttgataatt cctgaattgc tagtaaataa attagtatag tagttgtttt
     3361 aatttgtacc atacctaccc tccaaattat ttcgaaaggc cttcagcaat tttatccagg
     3421 ttccatttca tcatcgcata gtaactatca ccatcttgtc ctttttctgc aattgaatca
     3481 gtaaaaatcg ttgaatagat aggaatattg gtatcttttg atactgtttt cattggtcta
     3541 tcgtccacac tgctttctac gaataaggag ggaacttttg ttgtgcgtaa tttttcaact
     3601 aagtgtttta tttgatctgg tgttccttct tcttcagtgt tgatttccca aatgtaagca
     3661 gaaggcacat tatacgcttt cgagaaatat ttaaagcatc cttcacttgt aacaatcatt
     3721 tttttatcat tcggaattga agcaaattta gatttagctt ctttgtctag agaatccaat
     3781 ttttcaatat acttatctag attttcttta tagaattttt tattatcagg atctttttcc
     3841 gctaactgtt tttcaatatt tttagcgtaa ataataccgt tttctaaatt taaccaagca
     3901 tggggatctt ccttcccttt ctcactctga ccctctaagt aaataacatc tatgccatca
     3961 cttgctgcaa aatagtcttt gttttcctct ttgttcgcat tttttactaa ttttgtaaac
     4021 caagcatttc ctccagtttc caagttaaca ccgttataaa aaatcaaatc tgcttttgaa
     4081 gttttttgaa catcttcagg caaaggttca tattcgtggg gatctttccc aataggtacg
     4141 atactgtgta aatcaatttt atcttttgct atattttcag taatatctgc taaaatcgaa
     4201 ttagtaacta ctacctttaa tttttcgttc gaagccactg tatctttgtc tttactattt
     4261 gttgaacatg ccccgaatat aaaaagagca atcaaaatcc ccagacttcc cagtactgct
     4321 ttccattttc tcatcataac tttctctcct tctttcttaa aaatttttgt tttggtgaga
     4381 ttagaaaact aattacaaat aagaatgccg ctgttaaaac aatacttgat cctgctgcta
     4441 tgttaaaact ataaccaatg aacaaaccta gcaatgatga gcacgctccg actgtcgccg
     4501 aaataaatat catagttttt aaactgtttg catataaata tgctgtagca gctggtgtaa
     4561 ttaacattgc aacaattaat atagttccca cactttgcat agctgttact gctactaaag
     4621 ttaatagaat cattaataga taatgataaa aactgacatt catccccatt gcttttgcca
     4681 ttaatggatc aaaagaagtg attaataatt ctttaaaaaa tagaacaact gtaaccaaca
     4741 ctaaaacaga aacgccaatt gtaatccact tatcaatatc ttgtacagct aaaatatttc
     4801 caaataagat atgaaataaa tccgttgagc tatttgcaac tcctataagg ataactccta
     4861 atgctaaaaa agaactgaaa gtaataccaa ttgctgtatc tccttttatt acactattgc
     4921 tttttataaa agtaataatg atagaagcta atagaccaaa tacaatcgca ccaataaaaa
     4981 aattaatacc taaaatataa gaaattgcta ctcctggcaa aacagcatga gaaatagcat
     5041 cacccataag agacattcct cttaaaataa taaaacaacc tactgttcca gaaacaatcc
     5101 ctataactac agatgtaatt agagcattct gtaaaaagtg aaagtcatac agaccattaa
     5161 taaaattttg aagcatatta ttccccttgt atattagagt tagggtttta accttccggt
     5221 tttgattgga taaccctatg aaccatcgtt attttaattt ggtattaact catttctttt
     5281 gagataatat atttattgga ttgagaggct aagccgttcc cccctctcca ataaatatag
     5341 tatctccata ggcttttttt aaattctctt cattaaatac agattctaca cttccgtgag
     5401 caattagatt tcgattcaaa agaataatat tatcaaaata cttctttacc ttgcttaaat
     5461 catgatgcac aattagcact gtttttccct gatgtttcaa ttcttttaac gtatccataa
     5521 ttattcgttc actaactaag tctatcccta caaatggttc atctaaaaat atgaaatccg
     5581 cattttgagc aagacatctt gctaaaagta cacgttgaaa ttgtcctcca gataattctc
     5641 ctatttgatg attagaatat tttcccatat cgaccttttc caaagccttt gaaactcttt
     5701 gccattctgc atttttaatt ctttgaaaaa ctttcattcc ggcatatgtt cccatagata
     5761 cacattcttt tacttttatt ggaaaagtaa aatcaatatc agctttttgc tctacatatg
     5821 caatcttcac cagtttttta ttgatatctt cattattaat ggagacctct ccctgatgag
     5881 ggataatatt taacattgct ttaagcaatg tagattttcc agcaccattt ggaccaataa
     5941 tacctgttaa agcaccttct tgtattttta aagaaatctc gttcaatgct aaaaaatcgt
     6001 tataacaaac attaagcttt ttcacttcta acataacttt ctccttctaa atgata
//
LOCUS       DADVXB010000148         6054 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.154, whole genome shotgun sequence.
ACCESSION   DADVXB010000148 DADVXB010000000
VERSION     DADVXB010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.154"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            202..1008
                     /locus_tag="KB902_002425"
     CDS             202..1008
                     /locus_tag="KB902_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6809201.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1020..2240
                     /locus_tag="KB902_002426"
     CDS             1020..2240
                     /locus_tag="KB902_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809202.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGTGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2230..3816
                     /locus_tag="KB902_002427"
     CDS             2230..3816
                     /locus_tag="KB902_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6809203.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3855..5993
                     /locus_tag="KB902_002428"
     CDS             3855..5993
                     /locus_tag="KB902_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6809204.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         2044 a          984 c         1285 g         1741 t
ORIGIN      
        1 aaatacgaga gaggctgtga caaccgtcgc agcctttttt ggtttattgc aattgtctag
       61 catcttctgt aaaatagaaa cgttagagaa aatcttgtat catagaaaat taagaaagaa
      121 ataagaacgc agctcggtac caaaaatatg gtaaaatggc acttgactgt aattcactga
      181 aaatcgcttg gaggaacaca aatgtttaaa gatttgtatt tatttatgaa ggacatttat
      241 cagaacagaa aattattgct acagttttcg atcaatgact tcaaatcaag atatgcagga
      301 tcgtttttag gaatcttatg ggcgtttatc aatccgctat ttactgtatt gatttattgg
      361 ctggtatttg gtgttggact gaaagcacaa atgatcgatg caaaataccc atttatcgta
      421 tatttagtta ccgggatgat tccctggttc ttcttctcag atgcatttgc atcaactacg
      481 gttgtttttc gggaatatac ttatttagta aagaaagtcg tattcaatat tcgtatcttg
      541 cccacgacga aaatcctatc caatctgtac acccatttat tcttcattct gattggcata
      601 gctgtcgcgc ttataaatgg tatatatcct tcagcaatgt ctttacagct gatttattat
      661 ttattttgca tgtgtgcttt cttgacagga ttgacttggc tgacggcatc gatccaacca
      721 tttttacctg atatcatgca attaattacg atcgtgctgc agttgatcat gtggacatta
      781 ccgatattat ggagccctaa tcagtttgat tcaggtcttg taagcatatt gaaattaaat
      841 ccgctgtact atgttgttca aggttatcgt gagtcatttt taagtgaagc ttggttctgg
      901 gagcatggaa catatacttt gtatttctgg gttttcacgt tagtaatgtt cgtaatcggc
      961 tctgcagtgt tccgtagatt gaaaccacat ttttcagatg tgctgtaagg agaatagcta
     1021 tgacagaata tgcaattaga ctaaaagata tcacaaaatc ttataatatg tacgcaaaac
     1081 cttcggatcg atttcgtgaa gccctcaatc cttttaagaa atcctatcat gatgtatttt
     1141 atgcgttgaa aaacgtgaat gtagaaataa aaaaaggtga gatgatcggt ttcgtgggag
     1201 aaaacggatc gggaaaatct acaatgttga aaatcattac gggagtactg acaccaacat
     1261 ccggcacgat ggaaatcgaa ggaaaaatct cagctttgct agaactagga acaggattca
     1321 atcctgagta ttctggctat gaaaatatct atttaaatgg aatggttcta ggattttcaa
     1381 gagaagaagt cgatgaaatg gtcgatgata tcattgaatt tgctgacatc ggagaccata
     1441 tttatcaacc tgtaaaaact tattcaagcg ggatgttcgt tcgtctagct tttgctgtag
     1501 caatcaatgt gaatcccgat attttgattg tggatgaagc attggcagta ggcgatcttg
     1561 aatttcaact aaaatgtatg gaaaaattta cagaaatcaa gaactcggga aagacgattt
     1621 tattcgtttc tcatgatatc agttcgattc gtcgtttttg tgatcgttcc tattggttga
     1681 aaaacggaga agtcgtcgaa tatggcgata cgatggaagt aacgacgaat tatgaaaact
     1741 ttttaaagaa aaaatcagtt aaaacagtgg atcggaataa aaaccaagta gaacggttcg
     1801 ccgctccaga tatcgtcgac gtgacgaaag cggaattgtt ggataaagac aaaaatccgg
     1861 tggatatgct ggaacaagga gaaaaactat acgttaaagt aacttatgaa gtaaaagatg
     1921 atacaatcaa aaatccggtt ttaggaattg cgctacgaac agtcgacaat ttttatgtat
     1981 gcggacttaa tactctacta gatggtatca agattccttg gaaaaaagga gagaatatct
     2041 tttatctgga gtatgaaaag ttaggtttgt tagctggtga atattatttt gacgttgcgg
     2101 tctttgaaga aaatgcaacg gttcctttgg tatataagac aaagtacatg aacttgtttg
     2161 tcagcggttc ttatatcgga gaaggcatcg tggtcttaga ccataaatgg gaagaaggga
     2221 ctcatagcaa tgaaatatga ttttgaaatg gacctagatg aacaaagcag tgtgggaaaa
     2281 attgccgcac agatcaaacc aggaagtaaa gttttagagt ttggtcccgg aaacggccga
     2341 ttaacgaaac atttaatcgg agcaaaacaa tgtgaagtga gcattgttga gttagataag
     2401 gaattgttcg attttgtcag cgaatttgct caagatggat tttatggtga tatcgaaagt
     2461 tttgagtggg caaactatta tgctggacag acatttgatt acgtcttgtt tgcggatgtt
     2521 ttagaacatt tggtagatcc tggaaaaaca ttgaagaaag tcagagaatt tttgaatgaa
     2581 gaaggagaga tcctgattac attccctaac ttggcgcata attctgtcat gatcgatttg
     2641 ttcaataacc aattgccgtg ggcttcttat ggtctcctag atgaaaccca taattctttt
     2701 tatactcatg atggcttcca aaaagttttt gaaaaagcgg gattattcat taatattgaa
     2761 gattatttgt acttagctgt aggtgataca gaattaaaat caacttatga agaattgccg
     2821 gaagctgtac gctatgattt caaaatgcga ccatttggtg aagtctacca atactttttc
     2881 tcattgatga aacatccagt agcacaaagt tccattgcag agccacaaaa ttctaattat
     2941 gtaaaagtgt tagaagtaac ccagcaaacg aaacaagatg aaacaatcca acaaatacca
     3001 ttcaataatt tcacagggga aaatgagaca ctaagtttcc ccgtatcaga aacaacagaa
     3061 agaatggtgt ttcgcttcgc gcaacaacct agctttatcg aattcagcgc agaagctgcc
     3121 ggagaaaaac taacatttat cgattcgaat gctgtagtca aaacagtaaa tgattgttat
     3181 ttgtttgatg ggaaagaatt accagagttc gttctaacgg atatttctgg gaaagaagtg
     3241 actatccatt gtcactatcg ctttatcggg gaattgacac caacaatgaa agaattgttg
     3301 gaaacgattc gtcccatggc tgaagtcaca aagcagcttt ctgagaaaaa tgacgaatta
     3361 gaaagagaaa atcatcatct tcttgaggaa aatacaagac tagaccatac gttaaaaaca
     3421 accacaaatc gctattgcac attgttggaa agtgatgaat ggacaataaa acatagacta
     3481 ggacgacgta agaaagaaac ttcgaaaaaa atccaagaaa aagaactttc tatatgtatt
     3541 gacgagaaaa tctgggatgc agaaacaaaa atattaaaaa tcatcggatg gggaatcgct
     3601 aattcggatc gccagccctt gtcctataag ttatcagctg accaatcgcc atttttcgaa
     3661 gcaattcctg tttcacgaga agaagtcaat caagcagaac agctcgcaaa aggaacagaa
     3721 gcgggatttg agttacgaat cctttgcgag caagaacgtt cattcttagt ggaagcagta
     3781 gctcaaaatg gccaatcatg gatcattgaa atgtaaataa tgattaactt ataaagataa
     3841 ggagtaaacg aatcgtgcaa aaaaaagaaa ttgccgtatt tatcgatcaa atcactcgtg
     3901 aacgggccac tggcgatttg cttattgtgg gctgggcaat tgatgaagtg accaaagaaa
     3961 tccctacgat aaaggtagaa aaagaaaatg tgattgctga agcaacacat gtcgtaagat
     4021 tggatatcaa tcatttatat aatcttgatg ttaagaccca aagcggtttt aaggtacgtt
     4081 tatcagggaa aatgagagga aaagccatct tagacttcca aacagcgaga catcaaaatg
     4141 gcatagctgt gaaattaaac ggtaaatacc cttatgatga cggcattgaa tcttcatggg
     4201 aaagaaaaaa aagattactg aaaaaaggga taaattatgc aaggactcat ggcgtaaaaa
     4261 aagcgatccg tcgggtcaaa ttggaattga agccaggatc gatcgactat gcagagtgga
     4321 tcagtcgtca tgagaaacca gatttgaaag agcaaaggaa agaagcacaa ggatttgcgt
     4381 accgtccatt gatttccata cttatgcctg tctataacgt tgaaatcaaa tggctcgaaa
     4441 aatgcattga ttcggtactg gatcaaacgt atgatcattg ggaactatgt atcagtgatg
     4501 atgcttctac tgatccagct atccgaaagt gtctggaatc ctatcaagca aaagatgata
     4561 gaatcaaagt cgttttccga aaagaaaatg gacacatcag tctggcaact aattctgcat
     4621 tggaaatagc agaaggagaa tttatagcac tcttagataa tgatgatgaa ttaccgccat
     4681 ttgcattata tgaagtggca aaagtgctaa acgtacatcc agaactggat gtgatctaca
     4741 gtgacgaaga taaaatcgat gcagatggca atcgctttga tccgcatttc aaagcagact
     4801 ggtcgcctga tacattgatg ggaaataatt atatctctca cttaggcgta tatcgaacaa
     4861 gcattgttaa agaacttggc ggtttccgta aaggctatga aggttctcaa gattatgatt
     4921 tggtccttcg tgtgacagaa caaatccctg cagatcatat ttaccacatt gaccgagtct
     4981 tgtatcattg gcggacgatc ccaggatcaa ctgcaagtaa tggcgaagcc aaaagttata
     5041 tctatgattc cggagtgaaa gcattgacag atgccctgtc tagaagaaac atcaaaggaa
     5101 gcgtacgtcc tggcagaatt tctggatttt atgagattgc ttatgacgtc ttgcaagagg
     5161 atttggtcag tgtgatcatt ccaacgaaga atggctatga agatctaaaa acttgtgtgg
     5221 attcgatcat cgaaaaaacg tcttattcaa attatgaaat cattattgcg gataacggaa
     5281 gtacagatcc aaaaatgcaa gaattatttg cagaatacaa gcatcagctg aaagaccgct
     5341 ttatcgtaga attgattgac attccattca attattctcg aattaacaat ttagcagcag
     5401 aaaaagcaaa cggcaaatac tttttattct tgaataacga tacagaagtg attgagccag
     5461 attggatgac ggtgatggtt tcttatgcac agtttgatcg aatcggctgt gtaggagcaa
     5521 aactgtttta tccagatgat acaacgcagc atgcaggagt attattagga atcggtggtg
     5581 ttgcagggca tgcattgaat aactatgatc gaacacattg tggttatttc ggccgattgg
     5641 tcattgacgt caattactta gcagtcactg cagcttgtat gatggtcaag gcagctgact
     5701 tcaatgctgt taacgggttt gatgaaacat tagaagtagc attcaacgat gttgacttgt
     5761 gcttgaaagt ttatgaactg ggtcgttaca atgtctatgc acatcaagca gaattgtacc
     5821 atttcgaatc taaatcaaga ggttatgaag atactccaga aaaacaaaga cgttttgctg
     5881 gtgaaatcaa aaaaatgcaa gataaatggc cagcatatat tgcgcatgat ccattttaca
     5941 atgataattt aacaaaagaa ggaatcggcg acttttcgtt gagaccagat taaactataa
     6001 taaaaagctg ttatgttgtg attcgctcgc acataacggc tttttatagt tttt
//
LOCUS       DADVXB010000149         6012 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.155, whole genome shotgun sequence.
ACCESSION   DADVXB010000149 DADVXB010000000
VERSION     DADVXB010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.155"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(108..719)
                     /locus_tag="KB902_002429"
     CDS             complement(108..719)
                     /locus_tag="KB902_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6809205.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(842..967)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(1049..1765)
                     /locus_tag="KB902_002430"
     CDS             complement(1049..1765)
                     /locus_tag="KB902_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6809206.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(1771..2340)
                     /gene="scpB"
                     /locus_tag="KB902_002431"
     CDS             complement(1771..2340)
                     /gene="scpB"
                     /locus_tag="KB902_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6809207.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(2324..3121)
                     /locus_tag="KB902_002432"
     CDS             complement(2324..3121)
                     /locus_tag="KB902_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6809208.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(3091..3462)
                     /locus_tag="KB902_002433"
     CDS             complement(3091..3462)
                     /locus_tag="KB902_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6809209.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(3481..4368)
                     /gene="xerD"
                     /locus_tag="KB902_002434"
     CDS             complement(3481..4368)
                     /gene="xerD"
                     /locus_tag="KB902_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6809210.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(4464..4937)
                     /locus_tag="KB902_002435"
     CDS             complement(4464..4937)
                     /locus_tag="KB902_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6809211.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(5042..5905)
                     /locus_tag="KB902_002436"
     CDS             complement(5042..5905)
                     /locus_tag="KB902_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6809212.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
BASE COUNT         1667 a         1285 c         1016 g         2044 t
ORIGIN      
        1 aaatcaaaaa aatactcaaa acaaacaaat aaaacgttta cattattgca tgtcttgtat
       61 ttttttccaa aaaaaaagac caagaaattt cttgatcttt ttgatattta tttgactgct
      121 gtatgacgtt gttcgaactg atgttgtttt cgacttaacc atggaagaag ttgcgcatgc
      181 agcactaaaa agacagcact cacgatgaat cctttgatca agttgaaagg aacgatccca
      241 atcagtacat agtttgctaa agacatgccc agcatctgtg ttgcgttcag ccctaaaaac
      301 attaagtaaa gaggcgtaat aacgaaataa tttgcgatac tcataaaaat agttagagcg
      361 atggttcctg taatgacacc taaaaatttg tttcttcctt tatgctgttt ctttacacta
      421 aagaaataat aaatcgggaa tgtaaagatc gttgttgata agaaactagc agtgtctcct
      481 accaaattat ccggagaaaa acctgtagtc agcagatgta atactgaacg caagaacgct
      541 gttgcaactc cggccgctgg accgaataag aacatgctga tcaataccga gatatcacta
      601 aaatcgatct tcaaaaaact aaaagccggc atgatcggaa aagcaaaata ctgtaaaact
      661 aatgcgatcg cagcaaacat cgctactgca accattttct gtacacgggt gttcttcatt
      721 tgaaatcctc ctgttaggac tcctcttcag cgaacttttt gacgtttctc tccaaatgaa
      781 aaaactctat tttccaggga aaatagagtt agagttattt gatcaagcgt cgtcaaataa
      841 gctctatctt ctttatccag actatactgt cggtatcgga atttcaccga ttcagctatt
      901 tttttgcaaa ataggtcgtg gactataacc accggtcggg aatttcaccc tgcccctgaa
      961 gacgaacctt atataatttt tgtttacata ttcattatac atatctattc aaaaaacgca
     1021 acatctaaca cttataaaaa gtaagtgttc attttgagtg gttcagcaaa ctgctgactt
     1081 cttttttgtt cagttcacgg taatccccag gacgtaggcc ttgtaaagtc agatctccgt
     1141 atttttcacg ttttagtttt tgcacaggaa gaccaactgc ttgaagcata tttttcactt
     1201 gatgattacg tccttcgtgg atcgtcaatt ccacgatact gtggtttgtc ttaggatcca
     1261 ctgataaaat ttggaattta gctggagatg tttttcgtcc ttcgatcttt attccttttg
     1321 tcaaaggtgc aagcatcgat tttgtagcga tcccttttac ctttgcaacg taaactttat
     1381 ccacttcatg ttttggatgt gtcaggcgct gagcaaaatc tccatcattt gtcagtagca
     1441 agatccccga agtatcgtaa tccagtcgac ctacaggata gatacgttct tttaccatcg
     1501 gcaaaagatc cgtaacaact tttcttcctt tgtcatctgc aacagcagaa ataactcctt
     1561 taggtttgta caataaatag taaccgtatt cttcttgata aattgggact tcatccactt
     1621 ccacagtgtc atgtttccca acttttatcc ctaattccct tacaacttgt ccgtttactt
     1681 ttacacgtcc tgcaaggatg aattcttctg cttttcgacg agaagtgatg ccagcgtggg
     1741 caattacttt ctgcaatctc tccattacaa ttattctcct ttattcattc catcaaagaa
     1801 tagatctggt gacacgtctt cttcaagtga aatttccatt tcttgtgtat caggcagttc
     1861 ttctaatgat ttcaaaccaa aataatctaa gaagtagcca gttgttccat ataatatcgg
     1921 ccgacctggt ccttctactc tacctttttc ttcaatcagt ttatgggcag ctagacgctg
     1981 taccgctcct gaaacctgaa ctcctcgaat ctgctcgatt tcagctcttg tgattggctg
     2041 tttataagcg atgattgcta aggtttcgac ggcggcttga gataatgtgt ttgatgtccc
     2101 ttgcgcatat cgcttaagta agggagccag ctctttttta gtcgttaata cataatggct
     2161 ttccgtttca aaaatatgca aagctgagtg cgagttttga gtgtaagatt cttttaattc
     2221 tttcactaaa cttgtgactt ctgcttcgct gagatttaac agtccgctta attcttcatt
     2281 actgatccct tcctcgccaa caataaaaag aagggcttca agttcactta atttcgtcat
     2341 gttcggtatc tcctactgct ggataaagca taattgattc atagttttct ttttgttgcg
     2401 caatgatctg cccttttttc atcaattcta gcaaagccat aaaagtagtg acaacttcac
     2461 ttttagaagg tgactcaaaa aaagaatcga aagtacagcc atgcgcattt ctttttatac
     2521 gctcttcgat aaataccatt cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt
     2581 ccactttttg agaaaatttc ttacgttcta agattttctg catggcacgg atcaaatcga
     2641 tttttttgac ttgtcctcgc ttcaacggct tttcagcatc cgctaaccca tcgatgttca
     2701 taggttcttt tgtgtaataa agacttcgtt cctctgcttt ttctgtcagt ctttcagctg
     2761 catatttata tttacggtat tctaaaagct gagtgaccaa ttcttctcga ggatcttctt
     2821 cccataattc ttcatcgtct gtgacgaatt cttggacagg aagcaatgtc ttgcttttga
     2881 ttgccatcaa tgtagcagcc atcactaagt attctcctgc aacagctagc tcgagtgttt
     2941 tcattgtatg gatataattc atatattgct ccgtgatcgt agcgatcggt atatcatata
     3001 tatcgatttc catttgctga atcagatgaa gcagcagatc gagaggaccc tcgaatacat
     3061 ctaatttaat attgatctcc gtcaactcat tcactctttc ttctttttct ttgctagcca
     3121 ttttccaatg taaggctctg tgatttcagt tgcacggatg gagacatccg ggtacttttc
     3181 ctgtaattca tctaacattt gaaagcccat attctcaccg cgataagacg gattcaaaga
     3241 aatgtcatgg atgatcagct gatcgttcgt tgcccagtaa ataccaataa tcccttgaat
     3301 gttggttgaa ccttctggcg taaagaaaaa aagttcataa tcgtcttcag attcgtacgt
     3361 atcaatctcc ttcaacaaag aagttttacc tgtcagtttc ttatggaaac tcaatagtcc
     3421 catagcaatt ttacggtttt ctttccggta atgtgttaac atcttctcac cttcctatga
     3481 ctaagccctt ggaaaatgct gcttataaac atccgtcatt cttttcttcg tgatatgtgt
     3541 ataaatctga gtcgtagaga tatccgcgtg acctaacaat tcctgtactg tccgcaaatc
     3601 agctccattt tctagcagat gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc
     3661 tttgtaaatc ccagcctctc gtactaactg cttcagattt ttccagattc cttgccgaga
     3721 aagacctttc ccatgattat tgacaaatac atgcatttca gatgcgtcct ttacaagtaa
     3781 tggacgtgct tcgtctaagt agcgttccag ccattggatc gcataatcac ctaaaggaat
     3841 gatccgctct ttatctcctt ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc
     3901 tcccaatttc aatccaatca attcactgac gcgcatccca gtagcataca tgacttccaa
     3961 gattgcacga tctcttatcc ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc
     4021 tacttctgtc agagtcaatg tacttggtaa tttctgtgct ttcttcggcg tatcgatatg
     4081 ttgcatcgga tcatgatcag tgatacgctc ttgccgtaaa aactgatgga atcttctgag
     4141 acttgagatc atccgagtaa cagttgctgt cgcttttttt tcttcatgca acttctccag
     4201 aaaacggatg actaaaaagc gatcgacatc ctgccatgaa gcaattttct gctcctgtag
     4261 aaaatgcaag tactgttcca aatcacgttc atagctttgt cgtgtattgg cggacaatcc
     4321 ccgttcaata ttcaagtagt ggagataatc gttgatttgc tctttcataa taatccccct
     4381 catgcctctc tatcatatca gataccgctt cattctgata gtctttttcc ataatctgag
     4441 caaagaaaaa gccgtctaga cactcagacg gactggtttc ttttttcttt ttcatagcat
     4501 tcctgacaga ttccatggaa cgttagccga tgatctttta ctaaaaaatg ataacgttct
     4561 tctactactt gctccacttc aagtaaaaga tcctcttcta cttcctcgat cgtgccgcag
     4621 ttcaagcata gtaaatgatg atggaaatgt ttggcgcctt cttttctcaa atcataacgg
     4681 gctaatccat cattaaaact tactttatcg acaattttca attctgtcaa gatttcaagg
     4741 gttcgataaa cagtagcaag tccaatttcc ggactctttt ttttcactaa aaagaagatt
     4801 tcttctgcag ataaatgctc tttctcattt tccaaaagca caagcagagt agcttctctt
     4861 tgcggtgtca gcttaaaccc cgcttcatgt agctgctgtt ttgttttttt catcgccgaa
     4921 atagcattca tgaccattta ctcaacccca acaatttata ataattacaa ataaaaaaag
     4981 atataacact atgttaatta aaattattat aagctagtta agaaaaacat gcaagggatt
     5041 ctcaattaga ttttttgact agttttgtca caccgttttc ttgtgtaatc aatccttgtt
     5101 tcaaaagatt acctaatgcg cgcttaaatg ctcctttgct gataccaaaa gctttcatga
     5161 tttcttctgg atccgattta tctgtaaagt tgatttgctg atctgcagaa cgttctaaaa
     5221 tggttaaaat catttgtgca tcatctgata tagcttcata tgctcttggc ttcaatgaaa
     5281 gattcagtac accgtctggt cggacaccaa tcactcgacc ttttatctgc tcgcctagac
     5341 gaggttcatt atatcgttca gaaggatgga taaacccaag atagaaatct tccgttaaaa
     5401 cgtacgtacc tgttaatttc aagcggtatg ctgttcctat cacatctttg tttttcattt
     5461 cttctgttcc atatttgctt aaagatttga atattttttc atctgctaaa ctgccccaaa
     5521 tacggtcttt tgcatcaact ctaagggaaa tcatcaagcg atcccctttt ttaggccata
     5581 gctctgtcat tgtcggcaat tcatcaagag atacgacaaa gtctttatct ggaagaccga
     5641 tatcgacaaa cgcacctaaa tcttttcgtg tagcagtaac gattccaaaa gcgtaatgac
     5701 cgatacggct tttaggaatt tgtgtagtga tccgattttc atgtttttga ttttggtaac
     5761 cgaatccttc aactgcttca ccgattttgt gttcaccttc tgatttgctt aagccaaagg
     5821 tttgtccgtt tttttggaca aagtagtttt tttcattttc atcaataata atacctgtaa
     5881 atatagttgc taataaatcg ttcatttttt tctccctcta tagtgaaagg ttttcttaat
     5941 acatttcttt gctatcataa cataatgtta tctacttgaa tagctgagcc ttggtttgga
     6001 aaggtgaaaa aa
//
LOCUS       DADVXB010000150         6012 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.156, whole genome shotgun sequence.
ACCESSION   DADVXB010000150 DADVXB010000000
VERSION     DADVXB010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.156"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            374..1063
                     /locus_tag="KB902_002437"
     CDS             374..1063
                     /locus_tag="KB902_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6809213.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYETVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1050..2258
                     /locus_tag="KB902_002438"
     CDS             1050..2258
                     /locus_tag="KB902_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6809214.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2552..3823
                     /gene="serS"
                     /locus_tag="KB902_002439"
     CDS             2552..3823
                     /gene="serS"
                     /locus_tag="KB902_002439"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBB6809215.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDAEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYAHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4373..5857)
                     /gene="guaB"
                     /locus_tag="KB902_002440"
     CDS             complement(4373..5857)
                     /gene="guaB"
                     /locus_tag="KB902_002440"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBB6809216.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1841 a         1137 c         1169 g         1865 t
ORIGIN      
        1 actcagttat cttatcatgt catttccaac atgtcaacaa cttatttttt attatttaat
       61 aagttattgg tgttcttttg aacaaataat aatatatcaa catcacctgt gaaagtcaat
      121 aagaaaatgc ttatttatca acatttctag cttatatgat cattggttag ttctggacct
      181 ttttcgttcg tctttataac tctgagagac gtaaaatcct tttgttttca gtttaatgtt
      241 catgttcttg tcttattcac accaactaga tgtctcacct tctaaaattt tccttaacaa
      301 agtgctgctt ttatctattt ctgctttttt ttgctagaat aatagtaaca atatgactct
      361 ggaggattta tttatgaaaa ttttgattgc tgacgatgat aaagaaatcg ttgaattatt
      421 aagtatctat gttcacaatg aggggtatga aacagtaaag gcttatgatg ggaaagaagc
      481 attatctaaa atcagaacaa tccctgatat tgaattactt attttagata tcatgatgcc
      541 agagatggac gggatgcaag tagtgaaaga gctgcgaaaa gaatctcaaa taccaatcat
      601 tatgctgaca gcaaaaacta ctgatatgga taagatcaaa ggactggtcg ctggtgcaga
      661 tgattatgta accaaaccat ttaatccgtt agaagtaatg gctagagtaa agtctttatt
      721 acggcgtaca aaaatgcaga ttgccccaga tcagcctgat gtattagaag taaatgcatt
      781 aatcatcaat aaagactctc atgaagttaa aacaatcgat gggaaagaaa tccagttaac
      841 agctttggaa ttcggtatcc tctacttgct tgctagtcat cctaatcgag tatttagcgc
      901 ggatgaaatt tttgagcgtg tttggaaaca agaaagtatt gtctctgcta aaactgtcat
      961 ggttcacgtt agtcatttaa gagataagat tgaagaagca actggtggtg aaaaagtcat
     1021 tcaaaccgtt tggggagtgg gctataaaat tgacgcaaga tagtaaacga gcaactgaaa
     1081 aacgccgtcg gatcaatttg acttcaaaag aaatcagcga attgttagcg gaaggaatca
     1141 tcacgattat ccttttgctt ctattaaatg tttctattct ggttgttatc agttcggtga
     1201 tcaacagttc accttctttg acgaatgcga tttgggattc aaagaatatt tttgcagaac
     1261 gattgaacac tgatttgttc tggaacggcc ggaattttat tattcccttt ttctttctat
     1321 tagatattgg tgttttgtat tggcgcttga ttcgaagata tcgccaaatg caattgcggc
     1381 atatcatcag cgaacttcac tacatcgcaa acggaaatta tgatcatcgt atcccttttg
     1441 aactgagtgg tgacttaagc cgagtggtaa caagtatcaa tggattggtg gatagtaccg
     1501 tagcagcgat tgaagacgaa cgtaaaatcg aaaaatcaaa agatgaattg atcacgaatg
     1561 tcagtcatga tatccgtacc ccactcacgt ccatcattgg atacctagga ctgatagaag
     1621 atggccagta tcactcagaa gaagatcttt taaagtatac gcatactgct tatatcaaag
     1681 caaagcagat gaaatcttta gtggacgact tatttgaata cactaaggta cgccagcctg
     1741 ctgtcccggt gaatttttct gcctttgaca tgatccagtt gatcgaacag ttagcagctg
     1801 attttgagtt ggaagcttct aaaaaaaata tccaaatact tgttcaatca aaagtagact
     1861 cccttatcat ggatggcgat accgaaaaac ttgtacgtgt cttcaataat cttttgacga
     1921 atgcgttgaa atacggaaaa ggagcaacga agatcgtaat cgaagtagaa cgtatcggtt
     1981 cagaagttgt tgcaacagtc aaaaataacg gagcaatgat cccacaacag gcaatcgata
     2041 atctattcga ccgtttttat cgtgtagaag aatctcgttc acaagcaact ggaggaactg
     2101 gacttggttt agcaatcgct caaagcattg tggctttgca cggcggatac atttatgcaa
     2161 aatcagataa gcaatggact tctttcatca tgcaccttcc aatcaagaaa aatgaaaaat
     2221 tacctattga tacacaggaa gttattgacg aaagctgaaa tattcgctat tcttattaca
     2281 attattagaa taaatgaaaa acacagaacc cagtacactt tattcttttt cagagagctg
     2341 atggcaggtg taaatcagca aaggataatt tggaagttcc agttcgttta cgtgcccttt
     2401 cgaaataaga aaggtcggtt caacagccgt tatgtgttca acaagtgcag ctgacgctga
     2461 acttgggtgg taccgcgaat ttcagactga ttcgtcccaa gaataatggg atggatcagt
     2521 ctttttttat tttcaaaaag gaggaaatca tatgttagat gtaaaaatga tgcgacaaaa
     2581 tattgaagaa gtacaagaaa aattgatgac tcggggcgta aaaaaagaaa cattagctga
     2641 attcatggaa ctagatgaaa atcgtcgtaa gctactagtc aaaagtgaag aattaaaaaa
     2701 atatcgaaat gatgtttctg ctgagatcgc ccaattgaag cgtgcaaaag aagatgcttc
     2761 tgctaaaatc gctgaaatga aagaagtcgg tggcaacatc aaagcattgg atactgaaat
     2821 tgctgaagtg gatgaaaagt tgaaacaaat tgcaactact ttgccaaacc ttccccatga
     2881 ttctgtgcca gttggaacag atgaagagga caatgtagaa atccgtcgtt ggagcgaacc
     2941 acgtacattt gcttttgaac caaaaccaca ctgggaaatt gcagaaaatc ttgatatttt
     3001 agattttgaa cgtggcgcaa aagtagccgg tagccgtttt gtctattaca aaggattagg
     3061 tgctcgatta gaacgtgcag tctacaactt catgcttgat cagcatattt acgaacacgg
     3121 ctatactgaa atgatcactc cttatatcgt caacagtaaa gcgatgtttg gtacgggaca
     3181 atttccaaaa ttcaaagaag atgttttcca attggagaat actgatctaa cgttaatccc
     3241 aacagctgaa gtaccattaa ctaactatta taatgatgaa attttagatg gtgcagattt
     3301 acctatttat ttcactgcac taagccctgc ttttcgttct gaagccggaa gtgctggtcg
     3361 ggatacacga ggactgattc gtcttcacca attcaataaa gtagaaatgg tcaaattttc
     3421 ggatgcagag cattcttacg aagaattgga aaaaatgaca gctgatgcag aagatatctt
     3481 gaaaaaattg catttgcctt atcgtgtgat ggccttatca actggagaca tgggcttttc
     3541 tgcagctaaa acttatgact tagaagtatg gatacctgca caagatactt atcgtgaaat
     3601 cagttcttgt tctaactgtg aagatttcca agcacgccgc gcaatgatcc gttatcgcga
     3661 taatgatgga aaaatccact atgctcatac tctgaatggt tcaggacttg cagttggccg
     3721 tacagtagct gccattttgg aaaactacca aaatgaagat ggttctgtca cagttccaga
     3781 agcgctcgtt ccttatatgg ggaatctgaa agttattaaa taaagaggtt gtgaaaaagc
     3841 cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa
     3901 attggactta ataccgagaa actggctttt gaacaccatt tatcgagagg ttgtgaaatc
     3961 agcgtcctgg cctgagtatt agagaaaaaa atggaaaaat agtccctcat attttaccgt
     4021 ttgttgaact aataccgagg gtcagctgat tgaacaccgt ttagtggaga ggtcgtaagc
     4081 ctacccccca gctccgagtt acaaggaaca aattcaaaaa acagctcttc atattttatg
     4141 aatgttgtac ttgtgattcg gaggtggcaa gggaacactg tttattcaaa aagaggctgg
     4201 gacagaagcg tttaactcca agaaataaga agaaattcac gaaaattgct tttcaaattt
     4261 ttgtgaattt cagcttattt ccgaaggagt tgcttctgct tccgccgttt atacgtgttt
     4321 agagcgtgag acaaaagtat tctttacttt tgtcccacgc tctttaatgt ttttaagatt
     4381 caactgaata gtttggtgct tcttttgtga tttgtacatc atgagggtgt gattctttta
     4441 atccactgcc gctcatttgg ataaattgcg cttcatcacg taattgctgt agattcgctg
     4501 ccccaacata acccattcct gaacgcaaac cgccgatcat ttggaaaata atatctgcaa
     4561 cacttccttt ataagcaacc cgaccttcga ttccttctgg tactaattta tttgcttcat
     4621 tgacactacc ttggaagtaa cggtcttttg aacctttttc catcgcgcct aatgagccca
     4681 tacctcggta tgttttgaat cgacgtcctt ggaagatttc gaattcacct ggtgattcat
     4741 ctgtccctgc caacatactt cctagcatca ctgcatgtcc gccggcagct aatgctttga
     4801 cgatgtcacc agaatacttg atccctccgt ctgcaataat cgctttgcca tattgacgag
     4861 caactgatgc tgcatcataa atagctgtga gctgaggtac acctacaccg gctaccacac
     4921 gtgtcgtaca aatcgatcct ggtccgatac caacttttac gacatctaca cctgcatcat
     4981 ataaagcttt tgtcgcttca gccgtcgcaa cgtttcctgc aatcaatgtt gcatctgcaa
     5041 aagttgaacg gatttcttga atttttcgga tcacacctgc actatgtcca tgagctgtat
     5101 cgatgatgat tgcatctgcc cctgcttcta ataaagcatt cgcacgctca aatgtatcgc
     5161 ttgttacacc aacggctgct gctacaagca atcgaccatg ttcatctttt gctgcatttg
     5221 gaaattcgat cactttctcg atgtctttga tcgtgatcaa tccgcttaaa cgaccttcgt
     5281 tatctacgat tggtaatttt tcgattttat gtttttgcaa aatcttttct gcatctttta
     5341 gagaggtacc tactggggca gtcactaagt tgtcttttgt catcacatca gcaatcggca
     5401 tgtgataatc tgttacaaaa cgcatgtcgc ggtttgtaat tatccctacc aattttctgt
     5461 tttcaagtgt ttcaacgatt ggcacaccac tgatacgata tttgctcatc aattcttctg
     5521 cgtctgctac aagatgctgt ggcgttaaga agaacggatc aatgattacg ccactttcag
     5581 aacgtttgac ttttcttact tcatccgctt gctggctgat tgtcatgttt ttatggatca
     5641 cacctagtcc gccttgtctt gccatagcaa tggccatctt gctgtcggta acagtatcca
     5701 tacttgcact gatgattgga atattcaact taatattttt agctaattgt acgctcatat
     5761 ccacttcgtt tggtaacacg tgactttctg ctggtatcaa taagacatca tcaaaagtaa
     5821 atcctttttt cgtgaacttt gtttcccagt tggacatttt tagtaccact cctctaattt
     5881 agtttatcta ttaaaataat tgattttttc atttaagtca atgatctact tggaatcaag
     5941 ttagctttct catagaatac caatataaag cgtttacatc tgtgtgtatt aaaagagatt
     6001 gtaaaaaagc tg
//
LOCUS       DADVXB010000151         5858 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.157, whole genome shotgun sequence.
ACCESSION   DADVXB010000151 DADVXB010000000
VERSION     DADVXB010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.157"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            192..1088
                     /locus_tag="KB902_002441"
     CDS             192..1088
                     /locus_tag="KB902_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6809217.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1238..2179)
                     /locus_tag="KB902_002442"
     CDS             complement(1238..2179)
                     /locus_tag="KB902_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6809218.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHADLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2305..3426
                     /locus_tag="KB902_002443"
     CDS             2305..3426
                     /locus_tag="KB902_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6809219.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3684..5186
                     /gene="eat(A)"
                     /locus_tag="KB902_002444"
     CDS             3684..5186
                     /gene="eat(A)"
                     /locus_tag="KB902_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6809220.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5214..5780
                     /locus_tag="KB902_002445"
     CDS             5214..5780
                     /locus_tag="KB902_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6809221.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
BASE COUNT         1922 a         1034 c         1228 g         1674 t
ORIGIN      
        1 taacaaattt tcagacaatt acaactattc agaaaacttt taggcgaatt ttaatagaag
       61 aatgatttat ttcatcatat tttcatacaa atgttaaatt ttcatacaaa tataggaaac
      121 gttttactgg ctttttacta tttaaacagg ctatcatagg aaaaagtgac agagaaagtg
      181 aggcggaaaa gatgaacaaa aatgacgtac tgctagttgc aaaaaataaa tcactttatt
      241 ttttgccttc catccgctct ttagatgttt ggtccggaaa agatttacta cagtcggaat
      301 tcattaaatc agctagacaa cagttggcaa attatcagct gatcgttttt ttagattatg
      361 gatttgatat ggagatggct cgacgcgtgc gcccatttac caatgcaaaa attgtgttat
      421 ttttttggaa tcacttcaaa gcagaacacg aggcgatgct gaagcaggca caagatgaac
      481 cggcaatcga tgagatttat cattttgatt ttttggaagc aaaagaactt gggctgaaac
      541 ataatagttc attttattcg aaacatatga atttttcttc tagcgaacca aagacggatc
      601 tattttttgg tgcaacgaat aatgggagaa aagaacgagc agaaagctat aagcaggaat
      661 ttataaaaag agatgttacg accaactatt tcattcttcc acatcgaggg aatgaacaac
      721 ctggatatct tacttatgaa gagtacctga aaaaaacagg ggaatcgcgc gggattctgg
      781 aactgttgcg ggagggtcag caaggagtga ctttgcggac atttgaatcc atgtattttc
      841 aaaagaaact agtgacggat aatcaagcga ttgctcatta tcatttttat cgtcctgaaa
      901 atattttttt gcttcgagaa cgtgatttag atgaattacc ggaatttctg catacaccat
      961 ttaagccaat cctatcagag ctattggaat tttatgatgc agaaaattgg gcaaaacgat
     1021 ttatcactaa cgattccact atttatgagc aatacgaata tgacctctcc tctgttgaaa
     1081 acaaataaaa aacctacatt ttgaagagat tatgtactga aacaaacaag cacaattctt
     1141 atggcatcat gagagttgtg ttttcttttt gatcttttat tgggcttaaa aaaagagaac
     1201 cagctgctga ttcagctgat tctcatcaga gagcctttta ttctgcgcca aggattcctt
     1261 cttttgcatg gactaattgg gtcaaaaagg cacaatatgg tgtagcaata tcatattttt
     1321 gtccttttcg ccaaatggca ccattgatgt agtcgatttc agtcaaacga tggtttttga
     1381 tcaggtcttg gtacatagat gggtaatgca acccgatgtt gtcaggatca taagtagaag
     1441 caatatgttg gtacacttct tcttgatcta gtatgattcc ttcttttgct gcgatagaag
     1501 caaattcaga tacgattgtt cgaaccatgc tctctgccgc tttttgcgcg cctagttcag
     1561 caatattaca atccaaaatc gtgcataaac cattcaatgt tccatttaca caagcttttc
     1621 gccaaatgga ataacgaacg ttatggctat agatcggatt taaatttgct tcttgaaaga
     1681 cttctacaac tttttttgta aatgcttcgc cttctggttc caagttctct agttcgattt
     1741 ctccatcacc taacaatgtg acttttccgg gaccagctag accagctgtc cacatcgtga
     1801 tcccaaataa gatatttttc tttggcacat atttttccag tacatcttca tgacctaatc
     1861 catttagtaa acacaaaaca taagtattgt cagtaataat ggattggatc gaacaaaaca
     1921 tatcatctaa ttgattggct tttgttaatg ctacgatcaa gtccgcgtgt tcgttgcttt
     1981 cgatgatttc ttctggtgaa tagattggca gttttgcgac cacttcttta ccgttaaagt
     2041 cagcaatcaa cccatttgta cgaatggctt caatgtgagc aggccaacga tcgatcaaga
     2101 ggacctcatt tccgctttga tgtagcatca atccgattcg gctgcccatt gctccggccc
     2161 cagctattgc gattttcatg ttttttctct cctttattca atgagttccc ttttagtata
     2221 tagaaaaatg gaagaaaata gcattgtttt gtttgaaaaa aatgaaaaaa agtgtcttac
     2281 ttaagaagaa agtgagggat acagatggat attttggcgg caattgattc atttaaagga
     2341 agtgcttctt catttgaact aaatcaggca gttctaaatg gctgggaaga tcgtaaagga
     2401 agaaaaatca atgtgccgat tgcagatggc ggagaaaata ctgcagaagc aatctattac
     2461 gcgctcaggg gaacatggcg taccattgat gggatggatc tcttattccg tcagcgaaaa
     2521 atcagctatt tattgacaac ttggcaagga aaaaacaccg cagtcatcga atctgcacaa
     2581 gcattggggt tagatctact tgataaacca acggatcaaa ctatccgact tgcttccagt
     2641 tatgccttag gagaacttat taaagatgca ctgcttcaag aagtagaaca aattattgtc
     2701 actttaggag gaagcgggtg tagcgatggt ggtctaggat tactccaatc cttgggtgct
     2761 tctttagaag ggtacacaga aggaaatcct ttattatcta ctaaaaaact tcattttgat
     2821 cgaagaaacg ttcttgtttc taaagtaaaa ttgattatcg ctgcagatgt taccaatcca
     2881 tatacaggtc aacaaggagc tgcttggcaa tttggaagac aaaaaggagg aatagatacg
     2941 acgctagctt tcttagataa acaagcagga aagattgctc agcaaataaa agatttctgg
     3001 gaggtggatt tagatgatat tccaggaagt ggagcagcag gcggtattgg tggagccctt
     3061 tttttgttgg gagcgaagat ggtttctggt ttcgatttag tcagccaaat cactggattg
     3121 gaaaaaaaga tcgaacaagc agatgtcatc attacaggag aagggcggat cgatcagcaa
     3181 acgatccacg gaaaagttcc atacggtgta gcagtgcttg caaaaaaata tcgaaaacca
     3241 ataatcgcta tttgcggaag tagagaccaa gagctagaag gactttctga ttttctccca
     3301 attgtcttaa gtattcattt gggtccaata ggtttagaag aagcaatgga acacaggcaa
     3361 acattagaaa aaacaaaaat cttaggacag acacttagca gatttttcac catcctcccg
     3421 aagtagttga caaaatcatt ttctttatgc tatcgtaatt tcaaatatag gacaaagtga
     3481 gggatccgtg cattgaaaaa ttaagtcgat tgatgaaagc tgcattcaga ctgtaccttg
     3541 tggagacaag gaagcagtgt gcagattttc gggattggct tggttttttc gatgtatggg
     3601 tctttttgtg tgtatccaac ccttgcatcc tctttagcca gttctgaaaa taggactggt
     3661 ctttttttac gaggtgatgg aaaatgtcta aaatcgaaat aaaaaatctg acattcggct
     3721 acgacagcca aggcacatta ttatttgaac aagcaaatct aaattttgac acacaatgga
     3781 aactaggact tatcggacga aacggtcgag gaaagacaac tttactgaat attctacaaa
     3841 acaaactacc ttatcaaggg caagtaatcc atcagcaaga atttgcctat ttcccgcaac
     3901 agacaaaaga taaagaacgt ttaacctatt acgtgttaaa tgatattacg gattttgaga
     3961 tatgggaaat cgaaagagag ctccaattga tgcaaacaga tcctgaaatc ttatggagag
     4021 aattcagcac actatcgggg ggagagaaga caaaagtcct actggcactt ttatttgtgg
     4081 atgacactca tttcccgtta atcgatgaac caacgaatca tttggatatc tctggtagaa
     4141 aacaagtagc ggcttatttg aaaaagaaaa aacaaggctt catcgtggtc agccatgacc
     4201 ggggatttat cgatgaagta gtggaccatg ttttagcaat cgaaaaaagt caactggaac
     4261 tttatcaagg gaatttctct atctatgaag aacagaaaaa acttcgtgat gaatttgaaa
     4321 tggctcaaaa tgaaaaattg aaaaaagaag tcagtaggct aaagaaaaca gcagctgaaa
     4381 aagccgaatg gtctcgttcc cgagaaggag ataaaacaaa gaaacaagtc ggattcatcg
     4441 atactgaatc tagacgagtg aataaaggag cagtgggtgc tgatgctgca cggacgatga
     4501 aacgatccaa agcaatcgtg aatcggatgg agacccagat cagcgagaaa gaaaaactat
     4561 taaaagatat cgaatatatc gattctttga cgatgaatag ccaagcgtct caccataagc
     4621 gacttttaag cgtagaagat cttcaattag ggtatgaaaa tctgttattc gagccaattc
     4681 attttacaat cgagcctcat cagcgggtgg cgatttcagg tcctaacggt gcaggaaagt
     4741 catccattat ccattatctt ctgggggcat tcaacggcaa ggttatagga gaaaaatacc
     4801 agccaaaaca tctgagcatt agttatgcaa gccaaaatta tgaagacaat cgaggaacgt
     4861 tggcggaatt tgcagagaaa aaccaagtag actaccaagc atttttgaac aacctccgaa
     4921 agcttgggat ggaaagagat gtttttcata acaagatcga gcagatgagt atgggccaac
     4981 ggaaaaaagt ggaattggct aaatctttat cacagccagc tgaactatat acatgggatg
     5041 aaccattgaa ttatttggat gtcttcaatc aagaacaatt agaacaactg atcttgaacg
     5101 tgaaacctgc catgttacta gtggaacatg atcaaacctt cctggataaa gtatctactg
     5161 agattatttc tcttgagaga atctaaccct tgtaatctca agaacaacaa ggtatggtta
     5221 aggggaactt tgccaacgaa ggagagaatc acatgcttta tgtaacgaga cacggagaaa
     5281 caacttggaa cgcacaagga ttagtttgcg gacgggcaga tgtgccgctg actgaaaaag
     5341 gacagatgca ggcacagaaa ctagcagaaa aggtagtaga tttgcctgtt ccaatcacga
     5401 aaatcatcca ttcccctctt caacgagcaa gagatacagc acaagcagtt gctgatcgtc
     5461 tcagcttgcc gctgaccgtt gatgaacgat tggtagaaat ggattttggg gattatgatg
     5521 gactgccaag caaagatgag aactttcaaa aagcacgttt agcgttcgct gtacgattcc
     5581 caaatgggga gtcagtctta gatgtgtatg cacggatcgt tcctttattg aaagaatgca
     5641 tcgaagacga agaaaatgtc tatctgttag tttgccataa tgccttgata agagtgatca
     5701 atgcttattt tcatccgatg cctaatgagg ggttctttac attcatggta gataatacag
     5761 aattggtttc ttatgagtaa ttatgttttt gtgttattta aataaaatat ttcaaggcac
     5821 tgcttttgct tagcagtgcc ttttttaggt tatgacaa
//
LOCUS       DADVXB010000152         5790 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.158, whole genome shotgun sequence.
ACCESSION   DADVXB010000152 DADVXB010000000
VERSION     DADVXB010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.158"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(146..544)
                     /locus_tag="KB902_002446"
     CDS             complement(146..544)
                     /locus_tag="KB902_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBB6809222.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(541..1314)
                     /locus_tag="KB902_002447"
     CDS             complement(541..1314)
                     /locus_tag="KB902_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6809223.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMVKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1311..1994)
                     /locus_tag="KB902_002448"
     CDS             complement(1311..1994)
                     /locus_tag="KB902_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6809224.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2161..3048)
                     /locus_tag="KB902_002449"
     CDS             complement(2161..3048)
                     /locus_tag="KB902_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6809225.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAAITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3045..3914)
                     /locus_tag="KB902_002450"
     CDS             complement(3045..3914)
                     /locus_tag="KB902_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6809226.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4051..5337)
                     /locus_tag="KB902_002451"
     CDS             complement(4051..5337)
                     /locus_tag="KB902_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6809227.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTGWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5610..>5790
                     /locus_tag="KB902_002452"
     CDS             5610..>5790
                     /locus_tag="KB902_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6809228.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMP"
BASE COUNT         1797 a         1270 c          967 g         1756 t
ORIGIN      
        1 tttgaaaaga aagtctgatg cttagagtag aatttcataa aaatttacta tttcataagt
       61 attcacgaga aaaatacaaa caaaaaagcg gaaataacgc tcatccgcct tcttgtttgt
      121 gtttatttcc tcttcaaacg cttgtctatg attcagactt ttctctatcg ttattttcat
      181 ctaaaagttc ttgcattccg ataatttctc gatattgatg aatcttagtg ataccaatga
      241 ctttgtctac atcaatacta aaacaaatac cattacctgg aatatcgatg ttgatgcctt
      301 gaccaatcgc atccattact ttattcgtca aactatcggg tactaatgtc aacacaatat
      361 ctttttctgg cgaaatgtcc aaacctaaaa atttccctga atcatgtaca ccagaacctc
      421 ttccatgtaa gatcgttccg cctgctgcac ctgcttcttt tgaaaagtcg ataacatctt
      481 cgcccattcc tccgtcaacg atcgtcacaa tcatgtgaag attcaatgct acaagatctt
      541 tcatttgctt tcccccaatt tttgcaatct ttctttttcg attctgtctt tttcatcttt
      601 tcgtttataa atatatccta gtactaaagt ggataatatt ggtgtcaatg caatcattgc
      661 aaccacacca aacccgtcaa tgatcggatc tcttccttca atttgtgcag cgattgccac
      721 gctcattgat aaaataaatg tcgaacacat cgggcccgtt gctactccac cgttatcaaa
      781 agccattgct aaaaagatct tgtccacttt tcgtcctaaa ataaatgcta gcccgtatcc
      841 tgggatcaag aaataataaa gagagaatcc gacgagcaaa cgccacatag acaatcctac
      901 tgctgcgccg atcccaattg aaattaccat cagcatgatt ttcgatcgga ttctcccctc
      961 gctcaattct tcaacctgtt tgaccattac atgaatcgcc ggctcagcaa accctactaa
     1021 gaaccccatt aaaaagccaa ggggaaccag tatataattg taaggcaatc ccgcaatagc
     1081 actgcctaaa tgctgtccta ccggtacata agccatattg actccgtgca ggaaaaggat
     1141 caacccaata gtcgttatca agaaaccttt cataatgtca aagaaacgct ttttgcgcat
     1201 acgaaaacta atgatattca ttaaaacaaa taggattacg ataggtgcca ctgccaaaat
     1261 gacttccatg gtaacgattt cgattccatc tatcacttgc tgccagaaac tcattggaag
     1321 atcaccccca aaatcatcac ggcaagaatc ggccctaacg aagcaatacc gaccattcca
     1381 aaactgtcat tttcattttt cttttgtttg atcatactag tcatccctcc ggcaagggcc
     1441 aagataaatg gaacagttac tggaccagta gtcactcccc ccgaatcaaa agcaatcggc
     1501 ataaattcgg aactggtgaa aaatgaggcg atcaaaacgc ctatgtagcc tatagccatc
     1561 aattgataat aggatagctt gaatacgacc cgaagcagcg caaaggctag aaatactcca
     1621 gtgccgacgc tgacgatccc aatcagcaac actctgccaa tctctccgtc agatatatca
     1681 tatacttgtt gtcccaaaac ttgcacggaa ggttcagcaa tcgtgatcac gatcccgata
     1741 gcaaatccca aactgaccaa aacagtcaaa cttttctttt tgatcatata tttccctact
     1801 agatctccga cttccatcat agaataatct gctccaaaca aaaagagcgt cattccgatc
     1861 atcatgattg ccgcaccaac cagaaatgaa gcgaggtctt ctccttctaa cggtgcaaaa
     1921 acaaacgtta aaatgacaat caggacagtc atcggcaata tagcagcaat cacttcttta
     1981 aaatttttta gcatgtatcc tcctccttta ctctttaagt ttaccttaaa atgaaagagt
     2041 tttcgagcac aaacttaaaa cgttatcatt taatttttct caacataaaa taacacacgt
     2101 cccaaaagta tctttttact tggaaaaatg actttgaagg aacgcgctta ttgtgttttt
     2161 ttattttaca gagccgatca ttccttgaac gaattgcttt tgcaaaacaa aaaatacgat
     2221 ggcagttggt aaagtagcga tgactaatcc agccatgatc attccatagt ctggtgtata
     2281 ggaagcaccc atagcagata aaacaagcgg aaccgtccgt ttatcaggag attgcaaagc
     2341 tactaagggc cataaataat tgttccagct actcatgaat gtgatggctg cagccgcggc
     2401 ataggtattt ttagccgtcg gcatatacac tctaaaaaaa atacttagtt cttttagacc
     2461 gtctaatcga gcggcttcta ctagatcttt tggaaaagat ttaacatttt gtcgaaagaa
     2521 gaagatcaaa aaagcagtgc taacagatgg caggatgaca accaagaaac tgttgattcc
     2581 caaaaccgtt ccgttcaatt gtgaaaacat tcgatataaa gggatcatca atgccgcaaa
     2641 aggaaccatc atcgatagca gtagaatatt gaaaattagg tcttttcgtt tactttgata
     2701 aatctcaaat ccatatcctg ccattgacga aatcagcaat gcaaacacag tggtcaccaa
     2761 agcgatcatc gctgaattcc aaagggaacg agtaaaattc agctcattgg aaaacaaatt
     2821 ttgaaaattg atgatcaagt tactgccaat ctttattttt cccgatgtga tatccacggg
     2881 tgtattcgtc attcccaaaa ccatccagac aaaagggaaa atggaaataa atgataggat
     2941 gcttaatgct gtatacttta atactgaccc aattgtcgaa cgaagttcta atgcttgttt
     3001 tttgacgttg gggcgttcga ttgtttcttt ttctaccata tttttcatcg actttctcct
     3061 cctactttcg tttggattat cgacaatatc acaataaagg aaacaataac aaaggaaact
     3121 gctgccgcat atccaaaatt aggcgtgaat ttataactca aattatagat gtattgagat
     3181 agggtggtcg ttgcatttgc tggtcccccg ccagtaatat tttgtacttc atcaaaaagc
     3241 tgcaatgtcc cgatcgtcga agtaatggaa gtaaacaaaa tgattggttt taaatttggg
     3301 atcgtcactt tgataaactg ctgccattta gaagcaccgt caatagatgc tgcttcataa
     3361 atctccgaat caatattttg catgcctgaa aggaaaaaaa tcatattgta tccagtccaa
     3421 cgccaagtga tcgaaagaat gatcagaact ctcgcccaaa ttggatgagt caaccagcca
     3481 atcggtgtgt caatcatacc aatgcccaac aacaagttgt ttacaaggcc agattgagaa
     3541 aatagacttt tcatgatcag agaataactg accatcgaag tgatacatgg aagaaagata
     3601 gcggttcgaa acaacccttt atatttcaac tttttatcat ttaaaaggtt ggaaataaaa
     3661 agtgctagaa acaacatgat cggtacttgt acaagtaaat acaggaatgt attaaaaaaa
     3721 gcttttttaa aagttgcatc tgtcaacatc cgctgataat tacctaaccc gttaaatgtc
     3781 atattgacag ggggaccact ttgaaaagac gtgatcaaag ccaaaaccat cggaataaaa
     3841 accatgattg atatcaaaat gactggcaag attaaaaaag catgcccgtt tttgaataaa
     3901 tctttctgct tcattctttt ccctccaatt ctatcattga ttatctacat gaaaagacaa
     3961 gaaagacaat atctgtaagg cagacgtgat cttttttgtc ttttcgtttg tctgatgaaa
     4021 aagcgaagaa attcactttt ttaccaccga tcaattagcc aattgtgctt ctacttgttt
     4081 ttgtgtatct gctagtacct tgtctgtctc ttctccattg atgattcgat gaagagcttc
     4141 agctacgact gcttcaattg cataggtctc atgtccgtaa ttcacttctg gtatttcaga
     4201 tgtccatgtt gaaaaatcgt caaagatctt ttgaccactg taaaattcag aagcttcttg
     4261 ataagcttct tgttcattcg cgctaagcat cgtagatact agtccgattt ctttcgcaag
     4321 agtgcccatc agttcttcat tcgaagcaaa cgttgcttct aggaaatctt tcgctgaatc
     4381 ttctccagct actcctttga tcacatacca gccagcgccg ccaaggttag aagcttgcgc
     4441 tttttgcaga ttttctggaa gtgcaggtat tggtgcaatc ttccattttc cagattggtt
     4501 ttctgctcct tggatcgttg aagaatacca agcgccagtt gggctagaag ctactgctcc
     4561 tgattgtatc gcagttactc cagcattcca gtcagaggtt tgttcgacta gatcttcttt
     4621 caaaagagtg gcaaacaatt caagaccata ctttaaagat gcattgtctt ggatcgtgac
     4681 tgtctcccca tcttcagatg tataccattc tcctgcctgt tgcataatca tccttactcg
     4741 accaaggtca gaaggattga cttcagcgat tttctttccc gtcttttctt tgacatctcg
     4801 cgctacttga atatactcgt cccacttcag attctccata tcctcttctg tataacctgc
     4861 ttctgccatc agatccgtac gatagaagtt tgctgttacg cccgaatcga aaggaacacc
     4921 gtatatttta tctcctactt tgtttaccgc aaatttatac ggtgcaaaat gatcttcctt
     4981 tacaatagca gacaaattag cgaatgcatc tggataagaa gtcaaatagc cttgtatcct
     5041 ataatcttca atcaagacga tattgggcaa tccttctgta ttcccgctcg ctaaagcggt
     5101 gttcagtttc tgaacgatat catcctgaga catcgtaaca acttctatct ctgtttcttc
     5161 gttctcataa actttttttg cttcattcac tgctttgata ttgaatgtct catcccacgc
     5221 ccagccagtg actttttctt ctttgtctgc tgtactacta gcacttccgc atcctgttaa
     5281 gaaacctgat gctgccgcta aacaaacgac tccagcaatt aactttctga tgttcatttt
     5341 tatccgctcc ttttccatcc attagttgtt tacgtttgct acattcatca taccaaaatt
     5401 tgaaaacggt ttctttatta ttcagatact tcaaaaattt ctcctaaaat aataaaaaaa
     5461 tacaaatcaa ctatgacaaa aggaataatc ttagcatcta gaccaaagat cgaaatggtg
     5521 aggtttcttt aaaataaaaa tatccttgca ttttctccta gaaataagta tttttaaatt
     5581 acaagactat tcttaaggcg ggtaaaaaaa tgccaatacg cgtaattctt atcgatgatg
     5641 aacagacgat tttagatgga atgaaacagt tgatcaattg gtctgagcac gggtttcaat
     5701 taatagggac tttttccagt ccgttgaaag cgcttgattt ttctttggta catgcaatcg
     5761 atatcgtggt cacagatgta atgatgcctg
//
LOCUS       DADVXB010000153         5768 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.159, whole genome shotgun sequence.
ACCESSION   DADVXB010000153 DADVXB010000000
VERSION     DADVXB010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.159"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            29..466
                     /locus_tag="KB902_002453"
     CDS             29..466
                     /locus_tag="KB902_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809229.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            561..1445
                     /locus_tag="KB902_002454"
     CDS             561..1445
                     /locus_tag="KB902_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6809230.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1669..4836
                     /locus_tag="KB902_002455"
     CDS             1669..4836
                     /locus_tag="KB902_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809231.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4856..5401
                     /locus_tag="KB902_002456"
     CDS             4856..5401
                     /locus_tag="KB902_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBB6809232.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5429..>5768
                     /locus_tag="KB902_002457"
     CDS             5429..>5768
                     /locus_tag="KB902_002457"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBB6809233.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDI"
BASE COUNT         1939 a          986 c         1287 g         1556 t
ORIGIN      
        1 atcaaaaaat gcacgtagaa gtagataaat ggagtggttt tgcaaatttc ttttatttct
       61 agaagttatt cacgtatacg gatttgtttt tctcacaaat aaaaaggcag gaagtacaat
      121 ggatcatttg tatataaaat atattcatca attttccgtt ttggtgttag gcacactaat
      181 tatagcgggg attgtcgcat ttattattca aggccgtgac atattaacag tacatcaaga
      241 gtttttcagt tatgcatttg gtattcctct gatcgctata aggtctgata acaaaaagtg
      301 gaagaaacgc tattacattc tcttgctatt tttgtgtttt tatctgccac ctaagatttt
      361 tactttatta ggtatacaat gcctatcatt ttcttttatt tcctatatca ttgttttaat
      421 tttcctcagt ttcatagtat ggatgtttta tcttgtcaaa aaataaatga atgtttcatg
      481 aacagtactt catcacagcc taattttttt ctttatgcta tcgttatatt aaagaaatca
      541 atcagaaggg aaagaaagtg atgaaaaaag ttttattagt ggtaaacccc agttcaggcg
      601 gtgaacaagc aaaggaattt gagcaattag cgatagcaaa attggaatcg gtgtttgatg
      661 aagtggtcgt cttgcataca aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg
      721 ctacggaagg gtatcatagt gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa
      781 tcagtggaat cgctgaacaa gaacatcggc caaatttcgg atttttccca ttgggtacgg
      841 tgaatgactt ggctcgagca ttagggatac cgctagaacc tgaggaagcg atcaatcatt
      901 tttcgattga atcagtcaag ccattggata ttggaaaaat aaatgacgac tattttatga
      961 atgtcgtcgc aattggctct atccctgaat caatcaatga tgtagatgcg gagaagaaga
     1021 cgaaatttgg aaaactagct tatttcatgt caggaatcaa acagttagct tccacacaat
     1081 cctactcgtt tcacgtagaa gttgatggaa agaaggaaga aattgagagc agtaccttgc
     1141 tgataggact aactaactca gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg
     1201 atgatggtaa gctccatttg gtttatttaa aagattcttc tttgatcgat acgcttaaaa
     1261 cattgccaga cctattaaaa ggagtagatg aatctacgaa aaatctagcc taccttactt
     1321 gtgagcaatt agttgtgtca ttagctgatg aggaagaatt gacgacgaat gttgatggag
     1381 atgaagggga taaattacct gtgacaatca aagtattgcc ctcacattta caggtttatt
     1441 gttaaaatgg aggttgtgac cgaggagttg gcgggagaac accgcttgtt cgggataagg
     1501 gactgtgaca agacttttgt cacagccttt tttttgtaca aaaaagaaat ttacacctaa
     1561 tagaaaaatt tttccataaa aatacatatt ttaaatatga aagtacaatt ggaaatagat
     1621 taaaacgata aaataaaatt gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt
     1681 gtaaaaaagc tgattgcgtc gattttgttt gtcttccctc tcttgatggt gacatccgtt
     1741 tttgccgatg tagagaaaac aaacgaatca acgcaatcag agaatcaaag ttttgacaag
     1801 actacttttt cagaagaatc gattacttct gaaactacag aatctcaaag tgaggcttct
     1861 actaataaaa ggcaagaaga aaataagaca agtgagacct cagaagtagc tgaacaaacg
     1921 tctgatagca gtgaagcggc actggcaaga gctgtttcag cggatgggta cagcgaagct
     1981 gccacaacag aagaactggc gcagcttctc gcagacgaat cagtaactaa gatccgactg
     2041 attcagcctt tgactttaga cagggaatta gagatcaaac gagatatcgt tattgatttt
     2101 ggtggattcg ctcacaattt cggcacacac catatttata tcaatgagat acctcagtcg
     2161 atcgagttcc agaattttaa aggaacagct gcacatccag gtggattgac accaaatatc
     2221 gatggaaatg ccattatcat tgcttatatg accgattttt ggggaagcag atatcatttt
     2281 acgggagaaa taaaatttac cgggacactt gatttgtatg atgggtccaa attaggactg
     2341 atttacgctc ctcgtgcaac tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa
     2401 ccagtgaagg aaggactgaa tgccgctccg ggtaaagcct atttttgtag aagctatcaa
     2461 ttgaatgtga tcaatggtag tcaactttat ggaccgtatc tagggaaatt ctacggtttt
     2521 ctagattcag gagatgagac tggtagtgga aaaacagcgc caggaatcca tatcttaagc
     2581 ggttcaaagg tctctcttga ttatgatcgg gcagatggcg ttagcgatga aggagaggca
     2641 gtcgatacgc tacctggtaa tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg
     2701 gtaaatacaa agatcaatat taccaatgac aacaatcgcg gaatcatcca aatgagaggt
     2761 tcaggatcga aagtcactgt atcgaatggt gggaaaatca ccatcaatac agcaactacg
     2821 ggcggatttc gcttgcaagg agattctagt caaatccatg tatcaagtgg tggacaaatc
     2881 tcggtcaaaa tggctggaga tgacgatcaa cccgggaaca atgggatgcg ttttgtagga
     2941 aaaggccttt ctttgatcgt agaaggagcc ggatcagtta tcgacatcga taagcagagt
     3001 gggcgttcca gcgcagttcg ttttgagaat ggtacgcaaa agctgacagt aaccaatgga
     3061 ggctcattga gggtaagaaa tacaggtgat ggcaaatctt acgtgaacag actcaatcaa
     3121 ggaaatcaag cgatccaatt ttatgacgct tctggttttc tagaaagtcc aggttcagct
     3181 gattttacag tcactggaga aaaatcaaat atcgatatac gcgcagattc cggagcaact
     3241 gtagatacaa ctggagatat tgatttaaat tttacggcag gtgaaaaaac ttatttagtc
     3301 atggtcggga aaacagggga agataagacc ggcatcatca gtggggatgt gttgaatgtg
     3361 gacttagaat ctcctaccta ttttgatttc caaaacaaac ggattggaag cgagaccaat
     3421 ggcataggcg gctgggtatt ccaaggaaat ggagattctt ctttaaagat cgcccattca
     3481 gaaatcgctt tatggcgaaa aacaggcgca acattcgata actttgaaaa agacccggat
     3541 tatttttctg atatgacaga cttatcgatc aatgggaccg acttaggcaa tttcgtatca
     3601 agccctagtg caggtttaac aaatgaattt gctcagacag gtgccggaat gaaaaattat
     3661 aatcgaatca gtgccaataa tcagctcccg atgattgaat ccttaagagt gccaacgaat
     3721 gcagataaaa aaatctatgg gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga
     3781 gatgcttgga caggcgaagt agaagtgact ttacgtatta cttacgcaga tacgacgaaa
     3841 tcatctgtag aaattactgc tctcacgcaa ggacaaacag atgaaaatga aggggcagga
     3901 tataacccat ggggagaagg cgaacaaggc ggcttgttcg aagttcaagt acccaatgat
     3961 gagagattaa aaacggagga tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc
     4021 caagaagtga cagaactgga ctctgccaaa acgacagtcg atgtgattcc tcctgaacct
     4081 gctaatttaa gtaccacatt gatcaatgca gcttctcgca cgatcacagg tacaggtgaa
     4141 gcaggagcct tggtttcatt gaaaaaaaat caagctgttt tgtcagaaac aactattgat
     4201 gatacagggg aatttgttct ttctatccca gaaaatcaac tttttgcagg agatgtatta
     4261 gaaattgtat taaacgacca agcaggagaa gctactgcta agggtgtgca gaacaagcca
     4321 agtaccaacg atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat
     4381 gccccgcctt ttgcacctgc tacgaagatc gtagtagaag gtggtctctc atttcttgcc
     4441 ccttccaaac tcgattttgg tcagatcaaa gcaactggtt tgacacaaga agcatttggc
     4501 caaatggata tacaggaaaa attatggatt tatgatcagc gagaaacgaa aaatccgtgg
     4561 atcttaacga taaaattatc tcagcctttc acaaatgatg caggattttc tatgcaggat
     4621 gtcctatatt tcaagaaagg agaggagtat caattagtga atgaagaaga actggaaatt
     4681 gtcagaggac aaaattcaac gaatgtgcaa gcagattatt cagaatattt aaataacggt
     4741 cgggcgttta aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag
     4801 ataacatgga cattagcaga tgcgccgaca gaataaagat caaggaggat gattgatgaa
     4861 tcgaatatgg aataaaagtc atcgaaacaa ctgctcttta cttatgatcc ttctccttgg
     4921 attcatcctt tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga
     4981 attaccggct aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg
     5041 gaaaacacag gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga
     5101 gacattgatc cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa
     5161 aagtaaattt gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga
     5221 aataactgtt cctcctcaaa gtgcggtcac tgagacactt tcactgaaag cgccagaaaa
     5281 agagctggct ggtgtggtcg caggagggat cacgtttcaa gaaaaaaaag agaacgtttc
     5341 taacaaaagt acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgatttg
     5401 aaatagcgaa aaagagtctt ccccagattt gaaattaaaa aaagcttatg cggatcaaag
     5461 cgatggaaga aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg
     5521 cttgactaca tcggttgaaa tctacaaaaa agaaacaaaa gagccttacc tttcaataaa
     5581 aaaagaaaaa atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg
     5641 aaaaaaatta gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg
     5701 ctggaatctc cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa
     5761 ggatattg
//
LOCUS       DADVXB010000154         5530 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.160, whole genome shotgun sequence.
ACCESSION   DADVXB010000154 DADVXB010000000
VERSION     DADVXB010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.160"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="KB902_002458"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="KB902_002458"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HBB6809234.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="KB902_002459"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="KB902_002459"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HBB6809235.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="KB902_002460"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="KB902_002460"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HBB6809236.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="KB902_002461"
     CDS             complement(4028..5044)
                     /locus_tag="KB902_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6809237.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5478)
                     /locus_tag="KB902_002462"
     CDS             complement(5146..5478)
                     /locus_tag="KB902_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809238.1"
                     /translation="MRKITMQSGLCERRIEKLTKKNSGNSMKKKKKKLLKQFAGIGNA
                     NVKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGI
                     EFKISDVQ"
BASE COUNT         1452 a         1370 c          970 g         1738 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata
//
LOCUS       DADVXB010000155         5484 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.161, whole genome shotgun sequence.
ACCESSION   DADVXB010000155 DADVXB010000000
VERSION     DADVXB010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.161"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            228..845
                     /locus_tag="KB902_002463"
     CDS             228..845
                     /locus_tag="KB902_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809239.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            886..1185
                     /locus_tag="KB902_002464"
     CDS             886..1185
                     /locus_tag="KB902_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBB6809240.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1219..1386
                     /locus_tag="KB902_002465"
     CDS             1219..1386
                     /locus_tag="KB902_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6809241.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1431..2036)
                     /locus_tag="KB902_002466"
     CDS             complement(1431..2036)
                     /locus_tag="KB902_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809242.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            2161..5148
                     /locus_tag="KB902_002467"
     CDS             2161..5148
                     /locus_tag="KB902_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBB6809243.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            5315..5484
                     /locus_tag="KB902_002468"
                     /pseudo
     CDS             5315..5484
                     /locus_tag="KB902_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
BASE COUNT         1846 a          916 c         1007 g         1715 t
ORIGIN      
        1 ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg aataaatata
       61 atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat gccttgattt
      121 tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt ctgatttaat
      181 ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg agaaaatttt
      241 tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt tccgcgaagg
      301 aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa gattttaaac
      361 gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc tatctacaat
      421 cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga gaattaacta
      481 aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact gctagttaca
      541 agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta ctcagctata
      601 tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta gaagctgcga
      661 aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa tttcctgcga
      721 tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat caattgggca
      781 tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg caccactttt
      841 cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga cttaacgaat
      901 caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc catcggtttg
      961 gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa tttcctggtt
     1021 tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa ggaacaaacc
     1081 gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt cgaattttat
     1141 gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt agtaaaattt
     1201 acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat tgaaataact
     1261 agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt agcaaaaagt
     1321 gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg ggtacatgga
     1381 acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt ctacaaatca
     1441 ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt tgcaatctct
     1501 gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa gcgtttttgc
     1561 ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc ggctttttga
     1621 gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt ttgtgcaata
     1681 taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc atttccagta
     1741 ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg tttcataaaa
     1801 gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga tgtaacgatg
     1861 acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg ctcagtatct
     1921 ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttccat cattgccaat
     1981 tgtcgatcca aattttgatc ttgtgaagat actcgaatat agccaatttt tcccataaaa
     2041 aactcctttt taaaagtgat ataatttaca tgtaaaattt acttgtagtt ttactgctat
     2101 catagcattt ttaaaaataa attttatgta gacttaaaat ttacttcatg gagggtttaa
     2161 atggatgaaa tcaaaagtaa caaaaaagca tttggcattt atttaggaga acctagtaca
     2221 gaacaattaa accaattttt ttatttgcat gaaaaagatt tagaattgat ggagactata
     2281 cgacgaccag ctactagatt aggttttgca ctacagttag tctcactacg ttttttagga
     2341 acttttatat tagatcttac caatattccc caaaatgtat tgagttatgt agcaactcaa
     2401 ctaaatattg atcctggaga aattatctac tatagcagga gacagaccag gtatcagcac
     2461 acaaaattga taaaatcaca ttatggatat caagatttca accaaccgga aatagaaaca
     2521 tacctagcta actggctttt aaatagagcg ctgtatacaa cagaatcttc agatatgttg
     2581 tttgatatgc ttctaaaaaa atgtctggat gaaaagattg ttttacctgg aattactact
     2641 ttttctcgtt ttgttgctag tgcaattgaa aaagctgaag agcatttata ccgacaattg
     2701 tctttggttc caactgaaga tgagagaaag cggcttctca atcatttaga attaattgga
     2761 actccagttt atggggcaat aatcaaaatg gacattttga gaaccccgtt agctgacgat
     2821 agtcataaag aaatagccag aggttttgac cgactaaagc aatttcaagc tttctctact
     2881 gaaaaatgga agatggaatc tattcctgaa gggaaaataa aagttcttgc aaattatgca
     2941 tttaaagcta aagctcaatt aattcaacga atgagtgaac agaaaaaact ggcgttgtta
     3001 gtggcattta ttttcatata caaacgtaag gctatggatg aacaaatttt agcactatct
     3061 aatttttttg aaactgtttt tagacgcgcc aaaaataagg aatctaaaga acgtcttcgt
     3121 accataaaag atctagatcg agccgcatcg acactttcag atattgtaga tttagtaatg
     3181 tccagtcatt ctgatactaa tgaactatcc cttcgcgatc gtatcttaga aaaatattct
     3241 gaggaaaatg ttaccgaagc tgtatcgcaa gttcggctat tggttaaaaa tgatcgtgaa
     3301 ccaatagcca tttctgaact tctgaacact tatcgaaagt tcagaaaatt tattccggat
     3361 attttaacta cactaacatt tgacagcaat gactacggta acaactgtaa ggaactctgg
     3421 accttcatta ataatagatt tcctaagccg attacttaca aaatgtttgg agctattaaa
     3481 catactcttc caaagaaatg gatttattac attcatgaat accctgaaca aactaataaa
     3541 tgtgtattga ttgcagctgt cgaattgtta attcaatctt taaaacgcca tgatatttat
     3601 attcctcaga gtgtcttata taacaatcct atggattgct tgattgatga gaaaacttgg
     3661 gttcaacaaa aatacgtttt attagaacaa ctagatcttc cttcttcagc aaatgaaatg
     3721 tctttatggt taaagaacga tttggaactg tcttataaag aagcgctaaa tcgttggcct
     3781 acttctaaaa tggccagaat agaaaatgca gatcgcctgg ttgtctctag acttaaaaag
     3841 acatatgaaa aaaaggaaga taagtctttt agacgtcgca ttcagcagtt acttcctaaa
     3901 attgatttgt cagatttgtt attggaagta aaccaacagt taaatcttac tcaatcattt
     3961 aaccacttaa gtgacaagga caccaaaatg aaagacttgg atattagttt attagcagtt
     4021 cttttatcag agtcctgcaa tattggtttt tccccggttt caaaagaagg atttgattct
     4081 ttaaagtatg atcgtcttgt ctatgtcaat catcattata ttcgagtgga tacactttca
     4141 ggagctaatc aaaaaataat acatgcacac aggaaacttg ccacctctaa gatatggggt
     4201 gatgggcata tggcttcagc tgacggtatt cgttatatca caccacaacg ttccctatat
     4261 tctagaagta atccaaaata ttttggccgt ggtcgtggga tcacattcta caattttgtc
     4321 tctgatcaat atatagggtt ccacggaatg gtcgtttcag ggacactgcg agattcgctt
     4381 taccttctag aaggattcct caatcaaccc agcgaattaa ctcctaatca gatcatgact
     4441 gatacagctg gttatagcga tatgattttt ggtctctttg gcttattagg gtttcaattt
     4501 agtccaagaa ttgccaatga taaaggaacc aaactttggc gaatcgacgc taacgctcac
     4561 tacggggaac ttgatacgtt gtctcaaaat tcaattaata tggaactgat ttatacccat
     4621 tgggaggaca ttcttagggt tgcaggttcg ttgaaatctg gaaaagtgaa tgcaacagaa
     4681 ttaacgaaat ctcttcaacg gaatgggcaa cccacgcctt taggaaaagc aataactgag
     4741 tatggaaaag tttataagac gaaacatcag cttcgttata tttctgacga aatatatgca
     4801 cggcaaattt tagaacaatt gaataagggg gaagctcggc atgccttatg ccgtaatatt
     4861 ttttatggac gaaaaggaaa actctaccag acttattatg atgggatgga agagcagctc
     4921 aatgcattag gattagttac taatgccatc atatattgga actcactgta tttagaaaaa
     4981 gtatttgaac aaatgaaagc tgaaggattc gactgttccg aagaaatgat acgcaggcaa
     5041 tctccactaa ttagtgatca catcaatttt gttggtaagt atacgtttag atacgaagct
     5101 gaattatcca acggtaagtt acgtccattg aatgtagaag aattctagca atgttcgggt
     5161 tttgcatgct accgcactat ttcgtatgac tgttccagcg aatcacttcg aatagaaaaa
     5221 gagaaaaaca cgagaacagc gttaaatcaa cgtttcttgt gtttttactt ttgtgctacc
     5281 gcactatttc gtttctatgt tccatgtacc ccgtaatcaa gaaaacttta ttaataatat
     5341 caagaaattt atcgttcatt tattggaaaa tgtacctacc gatatagaaa aattaaattt
     5401 ttctgattat caggaacaga aagaaaaaga agcagaaaaa aatattgttg gcaaatgccc
     5461 gaaatgcgga aacaatatta tact
//
LOCUS       DADVXB010000156         5419 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.162, whole genome shotgun sequence.
ACCESSION   DADVXB010000156 DADVXB010000000
VERSION     DADVXB010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.162"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(59..334)
                     /locus_tag="KB902_002469"
     CDS             complement(59..334)
                     /locus_tag="KB902_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBB6809244.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(306..1259)
                     /locus_tag="KB902_002470"
     CDS             complement(306..1259)
                     /locus_tag="KB902_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6809245.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1871..3364
                     /locus_tag="KB902_002471"
     CDS             1871..3364
                     /locus_tag="KB902_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6809246.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3499..3795
                     /locus_tag="KB902_002472"
     CDS             3499..3795
                     /locus_tag="KB902_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6809247.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3896..4747
                     /locus_tag="KB902_002473"
     CDS             3896..4747
                     /locus_tag="KB902_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809248.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4768..5051
                     /locus_tag="KB902_002474"
                     /pseudo
     CDS             4768..5051
                     /locus_tag="KB902_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1861 a          835 c         1019 g         1704 t
ORIGIN      
        1 ctaaaaatat agtaagtata ctaaatatat ttactatatc tagtatactt actatatttt
       61 aatcttttga tcgtctatta tatataatcc gttcctcgtc gtttaaagta tcaacatagg
      121 cgtccattgc aagtttgact atttcataca taggaatatc ttttgcataa ctaagatccc
      181 gaatggtttt tagtacggga ggatctactt gaactggttt tctttctttc gcagtgtact
      241 ttcgttcccc taactcgaca ttaatatcat ctttaattga aatatcttca gcaccaattt
      301 tcttcttatc tttgttcgtt ggtaataatg ccatttagtt taatctcctt tccaagaggt
      361 aggatatgat tggccattga gtcagcatat ttaggtgtat aatcaaatcc ttcaatatca
      421 ccatgttgtt catagtattc aattctttct tctaattctg taaagatgtc tgcaaaaata
      481 gcccaccatc ttcgatctac ataatcattt aattggatac cattctcacc atacatttct
      541 aaccgatccg agcctttaac aatgctttta aaaatgtttg attcaccata cttatcaatt
      601 gttttttgat agtttgcgtg ttgagaggaa cgtcgcactg agaaaagaac aggcaaaatt
      661 ccaatgattt gaagatgaga ctcttcaaaa ttcgtgacaa tcggaactaa aactttatta
      721 ataaaatctt ctgttccttc cattgcgtac cgttttaatt cttgcattgc aataatataa
      781 tctgcagcag ttaagaatgc acgaaccaca ttatctgttg atggtgggca gtcgataaag
      841 atataatcga aattttttct caattcttct aaaggtttaa tgaaggccaa tgatctctta
      901 cgacgatcag gatatttttc ggacaagtat tcattaagtt cttcagatcc aggagagcca
      961 gccataatat ataaatgtgg acttacttga gtaatacctg aaacccagtc cccttttttg
     1021 attgctgcag acatggatcg atcaaagcta gtaatttgat acgttgatcc aatgttggaa
     1081 gtagtatttc tttgttggtc ataatcaatt agcaacacgt ctttttcaaa aagttgacta
     1141 gaaacaatcg ctaataaatc attgtctgta gtcttaccaa tgccgccttt tctacctgta
     1201 agcattacaa cttttcctag tttatctgat gttttaaatg cagtccgtaa gttttccata
     1261 gttccctcca atttcctata ctaaatatat ttagtatact tcatatactt aatatattcg
     1321 atatatctaa tatactccaa attgataaga attcagactt tataaggaat atagtggata
     1381 tactaaatat atttgctata ttcagtatat cagatatatt caaaatgtca aaatatattt
     1441 gtgcgttttg cgttgacaat ttagagtgaa aagaggtaaa cttaattcta tagaaaccac
     1501 agataattca ctatttacaa agtagcaaaa gcagtggtac tctttaaaca gaaaaattac
     1561 ataaaaaaaa gagacggaaa taattgattt tagcagaatc aattatttct gaatcacatg
     1621 gttaggacat gtgttcacgc tcgtctcaag aatatgtaag tagctaccaa ctacttatat
     1681 taaaagttga tcggatacct tttccgattg cctttattct accaaaaaaa ggcgagcaac
     1741 tcaacagaag aacgtttatt tagtgtactt aaattaaata ttcttaaaca ctgaagagag
     1801 aacacatact atggctgaga ttaaagctaa actgtgttct ctttttgttt gagaaaggac
     1861 gttacaatcg atgttgagcg aaatttattc agctattctt aaaaacggct tacgtacata
     1921 caaatatcga aacagcacca tgaaacctgc aggtcatatt gattccagta ggagtggtgc
     1981 tatctttgcg taccgtagca agcaattaat gaatgttggg cgtggtatgg tcattacttc
     2041 ggaagaagct attttagaga acgaaaagaa actaacgcat tggacaccta atacctatcg
     2101 ctttggtact tatgcggatg attatcgaac agtggttaaa ggtcattctg agaaaaactt
     2161 aagtcaaatc aacacatttg tagttgatat cgattcaaaa gagaaccatc aaggcgaaat
     2221 tattttagcc tgtttagatc aagtgggcta catgccaacg ctaattttag aatcagatca
     2281 tggttatcaa gtttattttg tactaaagac accaggctat gtcacaaaga aaagcaattt
     2341 caaggtgatc gatgtagcaa aaaaaatttc aaaaacaatt cgtctacagt tggctgaaaa
     2401 attgtccgga gtggatctag gatgtaacca cttcggaatt gctcgattcc cacaagaaaa
     2461 taatattgtt tttaaagaaa tgaactatca gtattctttt gctgactgga ttcaatggtc
     2521 gatgaagctt gaatcagatc aaaaaacaaa agaagatcga gaacgaaaac taattgtctt
     2581 tcctgagaaa aaagaaattc gtcaagtaga tgaaccgtgg ttcgatatgt tacttcataa
     2641 agcaaacatc gtcggcggag aaggacgtct tggtcgaaat aatgtgattt tcacgctttc
     2701 tttagcttat tactcttcag gttatgcatt ggatacttgc gaatacaata tgttcacatt
     2761 caacgaacgg ttacaggaac cgctatctga agcagaatta gtaaagattg tacgtagtgc
     2821 ttattctggt aattatcaag cagcaagcag agaattcatt attgaattgt gccagcaatg
     2881 ggtttcacca accttaaaaa ataatgatct gttcattcaa cgacgtggct ggtggaaatt
     2941 taaaaagcca cgagatcaaa gaaaatatag tcataaaaat gaatggaaag aagatctatt
     3001 ggcttatcta agcgaaaaaa gtcttgctag tgagccttat ttgaacctgt caaaaaaaga
     3061 attggcttca caactaacga tgcccaagcg aacacttgat aagatcttaa atgagttacg
     3121 agaggagaat aaagtcttct acaaggtaac acgaggaaga aatggcggaa tgatcattgc
     3181 ttcagtcaaa acgttgttcg cgagggttat tcaactaagt aaagaaaaga gactagatta
     3241 ttcaacaagg atcacagagg tatttggact caacgagagc ttagtagaag agacatttag
     3301 acaattatca acccccttga accctcttaa agaagtgaat ctttttgaag tagatacagg
     3361 ttgaaaaata aaaggtgcaa attgccttat acaatatatc tatgatactt ctgtaggtgt
     3421 tgctcccttt gcctagctac gtgtaggtgg tatacttata actgcgtatg cagtcttatg
     3481 tatcatggag gaagttgtat gtcgttaaaa aattatgtct attcacatcc tgttaatgtg
     3541 tttatcattg gtcgtttggg attatctgtg gaagtgttct gtgagcttta tggttttaag
     3601 caggggactt tgtcttcttg ggttaccagg gaaaaaacag ttgcttcttt gccgattgag
     3661 tttcttcatg ggttgtcctt agcttctggg gagactatgg atcaggtata tgattgtttg
     3721 tgtgtgttag agcaggagta tattgagtat aaaatagcta acgagttaag aaaaaggaag
     3781 aagtatatcc agtagtagtt tttatttact taaaaaattg gttcattgag caacctatcg
     3841 ctgctaaagt agcaaaggaa aacgttaaag gaaagaattt agggaagaaa tcgaaatgaa
     3901 atcggacgac tggattgaac acacctggct tcctctgaaa agaaatagca aacgaaagaa
     3961 attttgggta ttgcaattat ggccattagg aaaactttgt agttacgggg cacgacttat
     4021 tcttgattta accgtttact cgattggagt atttggaacg gcttattact tgataaatga
     4081 tcccaatagg attgcagcat cagacatttt tacagtgcta atgacgttga tttttgtcat
     4141 gctattgtct atttttactc aattagtcat gcaatttacc aggcaaaaat taacagcagg
     4201 aaaacttttc aaaagcctat tcgatttaat tgttgtaaat gcaattctag cgactttaat
     4261 aaaacaaatt gaacaatctg gaagaacaac aaaaggagtg aaggattttt tattgacgtt
     4321 tattcacttt gtaaatggac acatgtattt gtttgaagtg ggtattattc tcttttttgt
     4381 cgggtatgta tccacgaaac ttattaaacg ttcaattgaa aaagaaattg aaattgacct
     4441 gattccgaca cttcttggtt atgagtacaa tgttgatttt ggaagatatg acgaattgat
     4501 caatacggat atcgttcaca cgagtatcca tgaatctact gttaagggca tcagatctat
     4561 tttaaaaaat ggccaggaaa tgaaagcaat agatcgaaga aaagagatct acaattttta
     4621 tgaagtcgaa gcaagcctac gatatggcat cggaaaattg tggttagatg gaagtaatat
     4681 tcgtcaaaac aaaccataca ttttttggaa cagtagtgat ttagaacttc caatgaaaga
     4741 taaataatta tggagaatcg tttgaaaatg attcctctat acaggattgt gcttatagtt
     4801 ggcatggagt taaaaacctt aaagaaggag cagttattca aagtgaaaga acgtcataat
     4861 cagttactat gtagtaaaac gggtacgatg aacattgaat accgaacaga atatttagaa
     4921 ttaacgaatc aaactgattt tttgttgatt cgaaagcaac aagagcaaga aaaaaattaa
     4981 tggctactta tagccaattg attgatgaat gggaacaatt caaggaatct aaaattccag
     5041 aacgtctcta aaagccttta tttgtaaaga gcataaggaa acgtgggaac actttttaaa
     5101 aaaagtgttc caataggctg tgcctattac gtttctcaaa aataaatgtg ggaacaaaat
     5161 atttaaaaat aggatagtga aaggatagtg aaggatagta aaaggagggt agtaggatag
     5221 caaaaaggat aggctccttt tcgctatcct ttttaaattg gaggaattaa tatggaagta
     5281 agaataagaa atgtggatga gaaaatcgta agagaaattg atcgaagatg tgacgaacgg
     5341 ttctgttgca aagttttaaa tctactatca aataaggtag aataatagaa aaagatagca
     5401 ggaggaatga cgatgaatc
//
LOCUS       DADVXB010000157         5408 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.163, whole genome shotgun sequence.
ACCESSION   DADVXB010000157 DADVXB010000000
VERSION     DADVXB010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.163"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..530)
                     /locus_tag="KB902_002475"
     CDS             complement(<1..530)
                     /locus_tag="KB902_002475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809249.1"
                     /translation="MIYQLLIVEFILILIMYILSNRCFISPAFIAIALFFLATCCVVY
                     NIEFWNVQYSKKTLWFITTGFLAMCIPEMYILFLDYLSKKRVDNYHQNQYKIEYVQIY
                     PSRQLNLIFALLSVVFFGVLLVEILRKGDYSTLGLYAIGAAKSDETQNSVIARFGISL
                     ITGLNLAYLYVFINNV"
     gene            complement(531..1676)
                     /locus_tag="KB902_002476"
     CDS             complement(531..1676)
                     /locus_tag="KB902_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HBB6809250.1"
                     /translation="MKKARVLAFYLPQFHPVRENDIMWGKGFTEWTNVAKAKPLFKNH
                     YQPQIPADLGFYDLRISEVRKQQAEMAKKYGVEGFCYWHYWFGNGKRILELPFNEVLQ
                     SGEPDFPFCLGWANHSWSNKTWQKSKHFTKDVVFLEQTYPGDEDYILHFKSILPALKD
                     DRYIKVDGKPLFLVFAPDSIPDSAHFISLWNKLAKENGFEGIYFVARVTSVDNKFDLS
                     SMTDVAVHNRFQRFLDMGYDAINSDMQRYAELKISGYWKRGIKSIMRKTVGNFSANLY
                     PYDKIMENFYCEEEKRECVHPQLIPRLDRTPRSGKDARVYVDSTPEKFGNAIDRALSY
                     VQDKEPEHRILFLQAWNEWGEGNYMEPDLVFGCEYLEILRKKILGEE"
     gene            complement(1673..2479)
                     /locus_tag="KB902_002477"
     CDS             complement(1673..2479)
                     /locus_tag="KB902_002477"
                     /inference="COORDINATES: protein motif:HMM:NF014075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HBB6809251.1"
                     /translation="MVNIKIRKVIHRIPPILKLMRFVVDVQNKYFYDKFCKNTDNIQR
                     IEKLRNKFLGETCFIVGNGPSLTMEDLELIKDKDCFAANLIFKIFDKTQWRPKYYFIQ
                     DRYADTGNELDDIDLEYMFIGDYYWRVRGMHNPNAICIHSEQSVGGKNIKFSEDISKS
                     IVSHETVTYSMIQAAVYMGYKKIYLLGMDHSYALTYNADGTVSEDKTIRSHFFEDKNA
                     NEVIASIVGMNQAYIRAREFCESNNIKIYNATRGGKLNWFDRITLEEAVK"
     gene            complement(2538..2726)
                     /locus_tag="KB902_002478"
     CDS             complement(2538..2726)
                     /locus_tag="KB902_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016396235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HBB6809252.1"
                     /translation="MVVKGTSDDFYHANDEGGLAWNDPEIGIEWPQVLGEYKGNASAE
                     GYIFEDDTPLNISEKGQR"
     gene            complement(3074..3208)
                     /locus_tag="KB902_002479"
     CDS             complement(3074..3208)
                     /locus_tag="KB902_002479"
                     /inference="COORDINATES: protein motif:HMM:NF013621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HBB6809253.1"
                     /translation="MKEKVIEYTTGVYDMFHIGHLNVMRNAKAQCDFLIVGVSTDEPV
                     "
     gene            complement(3549..4682)
                     /locus_tag="KB902_002480"
     CDS             complement(3549..4682)
                     /locus_tag="KB902_002480"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6809254.1"
                     /translation="MRQKIRVLHIAQAAGGVDCYIRMLLKYLDKEKFENILICSQDFC
                     ETDYANLVLSFKQIKLTREIDLNDLKAIVIIRKLIKKYNPDIVYAHSSKAGAITRVAK
                     IGLKNYCVYNPHGWAFNMRCSVKKKMLYTAIEKIAALFCDKIICISDAEKQSALKKRI
                     CCEDKLQVIFNGVDIEAYRNKAHGEVKRESLNIPQDAFVVGMVGRISPQKAPEIFIKM
                     ARLVKNKIPEAHFIIVGNGEQKALIEKYAAEHGFLESLHITGWVNNSISYIELFDVAC
                     LLSRWEGFGLALPEYMMVGKPIIATNIDAIPNLISNGKNGLLVPVDDETAACEAVFKI
                     FSDKAMAARLTSEATSVVLEKYNSKRVASEHAVLFEMLVKKRG"
     gene            complement(4594..5146)
                     /locus_tag="KB902_002481"
                     /pseudo
     CDS             complement(4594..5146)
                     /locus_tag="KB902_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
BASE COUNT         1729 a         1171 c          689 g         1819 t
ORIGIN      
        1 attacattat tgataaatac atacaaatat gcaaggttta atcctgtaat taaactgatg
       61 ccaaatcttg caataactga gttctgcgtt tcatctgact tagctgctcc aattgcatat
      121 aatcctaaag tgctataatc gccttttctt aatatttcta ccaaaagaac accaaagaac
      181 acaacagata atagtgcaaa aattaaattt aattgtctgc tagggtaaat ttgtacatat
      241 tcaatcttat attgattttg atggtaatta tccactcttt tttttgataa atagtctaag
      301 aataatatat acatttctgg tatacacata gctaagaacc ccgtcgtaat aaaccagagc
      361 gtcttcttgc tatattgcac attccaaaat tcgatattat aaaccacaca gcatgtcgcc
      421 aaaaaaaaca atgcaatcgc gataaatgct ggtgatataa aacatcgatt agacaaaata
      481 tacattatta aaattagtat aaattcaaca atcaataatt gataaatcat ttattcttct
      541 cctaatattt tctttcggag aatctccaaa tattcgcatc cgaaaaccaa atctggctcc
      601 atataatttc cttctcccca ctcattccaa gcctgaagaa atagtatccg atgctctggt
      661 tccttgtctt gaacatacga aagtgctcgg tctattgcat ttccaaattt ttctggagta
      721 ctatcaacat acactcttgc atctttacca gatcgtgggg ttcgatctaa tcttggaatc
      781 aactgaggat gtacgcactc tctcttttct tcttcacaat aaaaattctc cattatctta
      841 tcatatggat agagatttgc tgaaaaatta ccaactgtct ttcgcattat gctcttaata
      901 cctcttttcc agtatcctga aatttttaat tcggcatatc tctgcatatc agaatttatt
      961 gcgtcatatc ccatatcaag gaaacgctga aatctattat gcactgctac atctgtcata
     1021 gatgacaaat cgaacttatt atcaacagat gttactctag ccacaaaata gataccttca
     1081 aatccattct ccttagcaag tttattccat agtgaaataa aatgagcaga atctggaata
     1141 gaatctggag caaaaaccaa gaataaaggt ttaccatcaa cttttatata tctatcatcc
     1201 ttcaatgccg gaagaataga tttaaagtga agtatatagt cttcatcacc aggatatgtt
     1261 tgttccaaaa acacaacatc ctttgtgaaa tgctttgact tttgccaagt tttatttgac
     1321 catgaatgat tagcccaacc gagacaaaaa ggaaagtcag gttctccgct ctgtaacacc
     1381 tcattaaatg gaagttctag aattctctta ccattgccaa accaataatg ccaatagcaa
     1441 aaaccctcaa ccccatattt cttagccatc tcagcctgtt gttttcttac ttccgagatt
     1501 cttaaatcat agaaacctaa atctgcagga atctggggtt gataatgatt cttgaataga
     1561 ggtttagctt tagcaacatt agtccattca gtaaagcctt ttccccacat tatatcgttt
     1621 tcacgaacag gatgaaattg tggcaaataa aatgccagta cccttgcttt tttcatttaa
     1681 ctgcctcctc taaagtaata cgatcaaacc aattcagttt tccgccacga gttgcgttat
     1741 atatttttat gttattactt tcgcaaaact ctcttgctct tatatatgcc tgattcattc
     1801 caacaatact tgctattact tcatttgcat ttttgtcttc aaaaaaatga cttctaatgg
     1861 tcttatcttc agacactgtt ccatcagcat tataagtcag tgcataacta tgatccatac
     1921 caagaagata tattttttta tatcccatat aaacagcagc ttgaatcatc gaataagtaa
     1981 ctgtttcatg cgatacaatg gatttactga tatcctcact aaacttaata tttttgccac
     2041 caacagattg ctctgagtga atacatatag catttggatt atgcattcct ctaactctcc
     2101 aataataatc cccaatgaac atgtattcta agtcaatatc atctaattcg ttaccagtat
     2161 ctgcatatct atcctggata aaataatatt taggtctcca ctgggtttta tcaaaaatct
     2221 taaaaataag attagcagca aaacaatcct tatcctttat taattccaaa tcctccattg
     2281 tgagacttgg accattacct acaataaaac aggtctcacc taaaaattta tttctcagtt
     2341 tctcaattct ttgaatatta tctgtattct tgcagaactt atcgtagaag tatttgtttt
     2401 gaacatcaac cacaaatctc attagcttta gaataggcgg aattctatga atcacctttc
     2461 taatttttat atttaccata tttactcctt ccgaattaca atatcaacca aaaattcgtt
     2521 atctaattaa atgtttacta tctctggcct ttctcactaa tattcaatgg agtgtcatct
     2581 tcgaagatat acccttcagc tgatgcatta cctttatatt caccaagtac ctgtggccat
     2641 tcaataccaa tctcaggatc attccaagcc aagccgccct cgtcatttgc gtgatagaaa
     2701 tcatcactag tacctttcac aacgatattc ctttctttat taaactttta tcaactacga
     2761 taattcaact tttgatcgag tcctcatcaa tgatactctt aattacatga gtcaactgag
     2821 tgctggaaat accatctgta tggggaagat aaacaaattc aacaccggtt cccataaact
     2881 gttcttcata tttttcctac tgaggattgc ctttctaatc agaacccacg aacattttgt
     2941 taaatttata tttctcccat gccgcatact tatccttatc attttgaggg acaaccatat
     3001 cgacatactt tattgaattt acaatttcgg ctcgttctac atacggaata acaggtgtct
     3061 tatttttatc ttactaaacc ggttcatctg tactaacacc gacaatcaaa aaatcacatt
     3121 gtgcttttgc atttcgcata acattcaaat gcccaatatg aaacatgtca tatacacccg
     3181 tggtgtattc tataactttt tctttcataa atatctcctt taactgtgta tttcagagta
     3241 aaataggaat ctttctcatc aatctgcatc acactctaca tgtccaaata acatagaccg
     3301 aaaagtcaag aaagataatt ttccagtctg tgatgaacct tctctcttct acatacttca
     3361 catagagttc cattcattct tcgaaagata aatcatttcg acgcgtaaca atcattacca
     3421 tcgaacaaaa acgttgaacc acatacaaca ggcacattcc tgcggtaatt tctttaatgt
     3481 tttttctcct gagtcttcac ttaccccgat atagttaatg cgactcaaaa aatttcttgc
     3541 tttcatcgtt aacctctctt tttaactaac atttcaaaca ataccgcatg ttctgaagct
     3601 acccttttgg aattatactt ttcaagcact accgatgtag cttcggaagt tagccttgca
     3661 gccattgctt tatccgaaaa aatcttaaaa actgcttcgc aagcagccgt ctcatcatca
     3721 acgggcacca acaatccatt ttttccattg ctaatcaaat tgggaattgc atcaatattg
     3781 gtggcaatga taggttttcc caccatcatg tactcaggca gagccaaacc aaatccttcc
     3841 caacggctta ataaacatgc aacatcaaat agttcaatat agcttatcga attatttacc
     3901 cagcctgtaa tatgcagact ttccaaaaaa ccatgttctg ctgcatattt ctcgataagt
     3961 gctttttgct ctccattacc aacaataatg aaatgggcct ctggtatttt attttttacc
     4021 aatctagcca ttttaatgaa tatttctgga gccttctgcg gactaattct tccaaccata
     4081 cctacaacaa acgcatcttg tggtatattc aaactttctc tttttacctc tccatgagct
     4141 ttatttctat atgcctcaat gtctacgcca ttaaaaatga cctgcaactt atcttcgcaa
     4201 caaattctct ttttcagtgc tgattgtttc tcggcatctg atatacagat aattttatcg
     4261 caaaacagag cagctatttt ttctatagca gtgtatagca ttttcttctt aactgagcac
     4321 ctcatgttga atgcccatcc atgtggattg tatacgcaat agttcttcaa accaatttta
     4381 gcaacacgtg taatggctcc tgctttactc gaatgtgcat acacaatatc cggattatat
     4441 ttctttatca gctttctaat aattacgatt gcttttaggt cattgagatc aatttctcta
     4501 gtcaatttaa tttgcttaaa tgagagcaca agatttgcat aatccgtctc gcaaaaatct
     4561 tgcgagcaaa tcaatatgtt ttcaaacttt tccttatcca aatactttaa aagcatgcga
     4621 atataacaat ctacgccacc tgcagcttgg gcaatgtgta aaactcttat tttttgacgc
     4681 atttctgtcc tccattttac ttatcataac aaacagtata tctcgaatta ccagaaaaat
     4741 aatcttccaa tcagcaaaga aaactctctt atactacttc acattgatct ccatccattc
     4801 tttaaaggaa agttcatttc aattcagagc aatctgccaa taatagctaa gatcaggctg
     4861 tacatacaat tgctgtcttt catagcctcc atactgcttc atctttctca gcaatccaga
     4921 tttgggaccc acgatattca tatcttcctt gaaaatattc caaatctgag gagattcatc
     4981 atccacgaac acgaaacgaa acttatagaa cttgaacaat ttaccatttc ttccaactct
     5041 atcttgtgcg aaaacaggag tccgccggat catcaaacac aataactaac gctgtaatca
     5101 gtatcacagg acacaaatag caagtgttaa aatggaaaat atgaatactt ctccaatata
     5161 cccggactag ataactccct tttgttcata atccctcata ctcatcagat tcaccaaact
     5221 ttaccgttta tttttttcaa tagttcacca aatgactcca tctaacaagg tcaaatataa
     5281 aaaattaacg cattttcatt atcttttagg catttattaa tggagatatt tagtgttttt
     5341 ataacataat aaatgctcaa tgagagccta tgttgggtac atcaatatta aagtattcag
     5401 cactaata
//
LOCUS       DADVXB010000158         5393 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.164, whole genome shotgun sequence.
ACCESSION   DADVXB010000158 DADVXB010000000
VERSION     DADVXB010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.164"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            39..2366
                     /locus_tag="KB902_002482"
     CDS             39..2366
                     /locus_tag="KB902_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6809255.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2492..2821
                     /locus_tag="KB902_002483"
     CDS             2492..2821
                     /locus_tag="KB902_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6809256.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            2861..3865
                     /locus_tag="KB902_002484"
     CDS             2861..3865
                     /locus_tag="KB902_002484"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6809257.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3862..5291
                     /locus_tag="KB902_002485"
                     /pseudo
     CDS             3862..5291
                     /locus_tag="KB902_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
BASE COUNT         1906 a         1035 c         1071 g         1381 t
ORIGIN      
        1 gtaaaggatt atttgatgat tttttattga gaggagggat gaaaatgatt aagaaaactc
       61 aaaataaaat ccaacgtata tgtcaaaaac attttgtttc tagactcaaa gctgtatcta
      121 aaagaaaata cttacatccc attatgattt cgatcatctt gatttttact ttcttaggga
      181 gcttatcaag tatttatgta aacgtttata cagaaacgtc aaattttgct aaccaaacga
      241 cagaggagac aaatagtcca ccctattctg aaatacagtc catagaaagc accaatcagt
      301 ctagcaacaa cgagacaacc tcaaccacat cctcgactca actgattgat ccgacagaaa
      361 aagaaatcac agcagcaaaa gcagcagggg agaaagctta ttcagaaaca ggtagaagcc
      421 agacatttag tactgttgcg gccactgcga atttcaacgg acataccata ccagatggat
      481 atacagtgat atatgccaaa gatggagtca ttgttgcggt taacggatcg atgagtgcgg
      541 ataaaactgc gttacaaggc gtaaccaaag caatcgcttt tattgataac cgtccagata
      601 tccataatct gtttattggc tccacagtaa atggtactac tatcacattc ccaaaaagta
      661 tctatatggg ggtggctacc gctggaaata cgatcgattc agttacaccc aatgcggata
      721 aaagttattc ttttacaccc tcaacatggg gagggcttcc tgccggagga ggtatgagta
      781 ctttttcaat cggtatacag ttagcaaatg atattccatt cacggggtac tcgatcaaaa
      841 atgggcagat cgttgatggt aagggaaatg tttcaaattt tccaacctat caagcagcaa
      901 cggttcaggt caatgcgaat cggacaggaa ctttttctta tacagtcaat ggtggagcag
      961 caaaaatcgg aacgtacggg actacattat ctggaatcca tgtgggtgac aaagtggtta
     1021 tcactccaac agcagtaacg ggctattctt ttgcacaaac aaacggttct ttcacagccc
     1081 tagaaagtaa cgtcgatacg gtgacctata caggcaaaca aacaccaatc actattaagt
     1141 atcaagacta ttttggacag atgattgctc cttctaaaat aatgaatctt acttacggaa
     1201 gtgctgcaca agacctgacg actaatacgc ctactatcaa cggatatacc tttacagctg
     1261 tttcagcgac agaaacaaag aaccaatcag caatgagtgt tttagctagt ttagatacaa
     1321 atggaaatgt aatcgtaaag gacgcaaatg gaaaacagat ttctgaagtc atcctatatt
     1381 ataagacaaa tgcaacagta tcaatcaatg caaatggcag taagtactat gatggtcttt
     1441 ctgttgtacc gatcgttaaa tatgccttta atgataaaac agaatcaaca tcccttttaa
     1501 acaatgatct cagtattgat caaatcacat ggaatccaac tgatttcaaa gcgatgaatg
     1561 aaaagggagt tgaagtaact gcgcctactg aaattggaac ctatacgtct tggcaattga
     1621 caaaaagcgg actagctaaa ctagctgcca gaacaaacta tttatttact atcgtgcaga
     1681 catctgatgt ctatacgatt aagcaaatca gcggtgcggt agagctcagt ggcagtaaga
     1741 catatgatgg aaaagcaggt gtcccgtcaa tccatgtcaa gctagcagag ggtgtcacta
     1801 gttcgcttac tccagtacaa gtggcactta gcagtatgga ttacacagca gatgcacaat
     1861 cagcaaaaaa tatggttaat gctggcagct atacaattaa actaacgaat agcggaatag
     1921 acaaagtcaa agcagcaaat cccaagttgt catttactga tatagccaac acatcaggaa
     1981 cttataccat ctataaagct aacgcagtga ttactgtcga tgacgctgcc tttaattatg
     2041 atgcccaaag tcactcgatt tcggttggaa atctccacgt taccggtgtt gtcttaggcg
     2101 aatcattgga ttatacccta acagttaaca gccggacaga tattggatca caaatagtaa
     2161 cgattagttt aggcgaagga agtgtaaaca ataattatac gattatcgca acagataccg
     2221 ctaagttgac gatcaatccg actctcttgc ttccttcgac aggtgggata ggtctactgc
     2281 cctttgtctt tttaggactg atctttattt tttctggctt cttttatttt atccatcgta
     2341 agaaaaaagc aggtgaacag cgatgaaaaa aacaaaaaat gtacgtgtgg atatatttgc
     2401 tgttctcttt tttatcctac tggtcttttt tataggttct ccgactgtgt cagctagaga
     2461 atcacctatt acatttactt tgcataatcg aatgttcgaa agcgataaga tgccaagtat
     2521 cagtcaaaac gacggaataa atatcccgga taactttcaa ggagtaaaag ggttgaacgg
     2581 cgttactttc gctatatatg atgtctcgga tgaattttac aagctgcggt cagaaggaag
     2641 tagtgtggaa gacgcacaaa gaaaactagc acaaaaaagt gatagtgaaa aaatactggc
     2701 agaaaatgtg acaaaaacag tagacgagga agagggcatt gcttctttta gtgcatcgga
     2761 caaagatgag caaggtcgtg acgctgttta ccgatttgcg gaaataaaga cttcagatta
     2821 agtaaaagaa aaatcagcac catttgtcgt tgtgcttcct gtgacagatt catctaatca
     2881 taaattgacg accatccact tgtatccaaa gagcgaacaa aaaatacctg ctgcactcac
     2941 attaacaaaa acagtagaga ataagcagac agattttgca gatggggata aagttcctta
     3001 tctcatcacc gtaacaattc ctgagaacat caacgagata ggaacctata cgatcaaaga
     3061 tacagctgat cctcagttat ggctagaacc agaaacgatc gattttttga ttggtggaga
     3121 caagattcat acatttcaca cacaaaaaac aaaacatggt tttgtcttat cagattctgg
     3181 aaaagatctt agttcgtttg ctgggaaaaa attaacgatc cgttaccaaa tgacattgaa
     3241 agaaaacagt gaaaaaacga catttgataa cgatgtacgt ttgacgactg acaatcaaac
     3301 agtagaaaca catcttgcca tccaaacagg aggcaaacaa tttgtcaaag tggatcggca
     3361 aacgaaacaa aaactagcag atgctcaatt tctagtcaaa aaaaatgacc aatacttagc
     3421 gcaagaaaac gggataaatc attgggtagc caaagatgat tcaagagcaa cgatttttac
     3481 ttccagtaaa gatggaacat tttctgtcca tggattgtct tttggaagtt acgaactagt
     3541 ggagattaaa ccgcctaaag gatatatatt gagtcaatca accattctct ttgaagttga
     3601 aaaaggcagt tatgatccgc ttcatcctat accattggaa atcatcaacg aaccaaaagc
     3661 aaatccgacg aataatggaa aaacgccagt tcagatgcag acaaatggtc catcaaatga
     3721 aaaaaatgga ggaagctttc caaaaacaag cgaagagatg cttggaggtt tctcaatttt
     3781 agggttgttg ctagtccttt caacagggac agcttggttt tataaaaaac aacaaaaagg
     3841 aaacaatagg agggaaataa aatgaaaaac atcaaaacaa aaatatggac gtttttagga
     3901 actgctatca tgctgcttcc tttcgttctc ggcctaggaa ctgcagaggt ttctaggccg
     3961 tatcacctac accagaaaat gttacggtta atttgcataa attgaaattc acttcagcac
     4021 cagaaaatca aataaacaac ggaacggaat tgacatttcc gaatagcgaa ccgttgaacg
     4081 gcgttgaatt caacgtatat gacatcactg ctacgtacta tccaagtaaa gacacagcag
     4141 ttccagcaga cgctacaccc ttcgcaagtg taacgacttc tggtgaagga ttagctaacc
     4201 tgactcttcc aggtaaatct gatgggaaag atgctgtata cgtctttgta gaaacaccaa
     4261 agcccggtgt cgaaacgtcg ccaaatatcg tgttaagctt acccttttat aacccgaatt
     4321 catcagaccc tgacaaacct ttagacacga ttcacctata tgctaaaaat gtcatcaaag
     4381 aaagcaatat caaaatccag aaagctggga acttttcagg ggtagataag ttagcagggg
     4441 cgcaattcca gatcaaaaat tcagagaatc aattcgtgac cggttttgat gaaaacactg
     4501 gtgtcgctct ctatgatcct gctgagtcag cgttgacatt cacaactgat actgaaggat
     4561 ccatcagtgt caatggatta atagacggca attatacttt agttgaaaca aaagcaccag
     4621 atggttatca attaaccaat ccacaaaaag aaactacttt tatagtaaaa aacggaaaat
     4681 tgcaacaaac aaccggtatc atccatggcg cagatgaagc caatcttggg aatccaaacg
     4741 gtgtagtcaa tcgggaaaat acaactacgg ataacacgat tactgtagaa aatgtccaaa
     4801 actacggtga tttccacttc atcaaacaag atgtgaacac gcaagaaaaa ttagccgatg
     4861 cagaattttc tattctaaga gcaaaagatc caactgttaa attaatgaaa aaaatagcaa
     4921 atcttgcctc aggagaatac ccatatgctt ggtcagatga agtcacaggt tctgactggg
     4981 aagaagtgaa attgatttct gattcagaag ggaaattttc aatcgaaggg ctgaaacaag
     5041 gggcatactg ccttcaagaa acaaaagcac cagaaggcta cgcattacct aagaatgaag
     5101 ctgcgtacac tgaatttaca gtagatgatg atccaacaac ttctgatgaa acaacgatcg
     5161 ataaccaacc taaaggaatc ttgccttcaa ctggtggtat ggggatcatc gtattcatct
     5221 tggtaggtac tgctttagtt ggaggagcag tgatctactt caaaaaacgc catcaagaaa
     5281 cagaagctta aactattgga aacaaaaatc atacgataaa taaacgatag tgattcaaat
     5341 ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt cgctcaacaa acg
//
LOCUS       DADVXB010000159         5355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.165, whole genome shotgun sequence.
ACCESSION   DADVXB010000159 DADVXB010000000
VERSION     DADVXB010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.165"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(116..1264)
                     /gene="nagA"
                     /locus_tag="KB902_002486"
     CDS             complement(116..1264)
                     /gene="nagA"
                     /locus_tag="KB902_002486"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBB6809258.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1340..2176)
                     /locus_tag="KB902_002487"
     CDS             complement(1340..2176)
                     /locus_tag="KB902_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809259.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2360..3577)
                     /locus_tag="KB902_002488"
     CDS             complement(2360..3577)
                     /locus_tag="KB902_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6809260.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3726..3905)
                     /locus_tag="KB902_002489"
     CDS             complement(3726..3905)
                     /locus_tag="KB902_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809261.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3960..4043
                     /locus_tag="KB902_002490"
     tRNA            3960..4043
                     /locus_tag="KB902_002490"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3994..3996,aa:Leu,seq:gag)
     gene            complement(4283..5281)
                     /locus_tag="KB902_002491"
     CDS             complement(4283..5281)
                     /locus_tag="KB902_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809262.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1674 a         1085 c          845 g         1751 t
ORIGIN      
        1 caataggaaa ttaaagaaac ttttgaaact tatgtaaagt gatttttact agaacacaaa
       61 aaaaacctta aaaccaaact taagaagttt agttttaagg ttaacttaaa ttatattatg
      121 cgtggaaacg ttccacgcca tctagataag ttgcttccaa tgtcatatca gggttcaata
      181 cgataaagtc tgcatcgcgt ccttgagcga tttttccaca tgtatcatcg attttacagc
      241 tgattgctgg aatcagacta gccatcatga ctgcttgttc tggtgttgct aatccccagt
      301 ctacaacatt tttaattgct tctttcaatt tcaatatact tccagctaag ttgccagatt
      361 ctagacgtgc tgttccttct tttactacta ctggaaattc gcctaaattg taatttccat
      421 caggcatccc accggccatc atacagtctg taattaatgc gacatgatca tgtcctgctt
      481 tttccattag gattcccgca gcatttggat gtacatgatg gccatcacaa atcaattcag
      541 aaaagacatg ttctaaagat aataacgcac ccaccatacc tggttcgcga tgattcaatc
      601 cacgcatacc attgaaagca tggacaaata cacttgcgcc tgcttcaaca gctttttgcg
      661 cttcttctag tgtagcatta ctgtgtccta gagaaacaac tactccttct tcagtcactt
      721 gtttgacaaa ctcttctaca ccttgacgtt ccggtgctaa agcaattttt ttgattaaac
      781 cacctgaagc ttcttgccat tcatggaaag tatccaaatc aggatccccg aaataacttg
      841 ggttttgtgc ccctttgtgt tcttctgtga agaaaggacc ttcaaaatag attcctttga
      901 ttttagctcc tggtgcttcc tgatacattt tgccgattgt ctcagctaca tcttttaaac
      961 gttctttgct tgacgtcaat gttgttggta aaaatgaagt cactccacaa gataacagac
     1021 cttcagacat cactttgatg ccttctgcat cattatccat tacatcatga ttcatatagc
     1081 cgtgaatatg tgtatctacc aaaccaggag caatccattt gccgctttgg tcaatgatgt
     1141 tgacttctcc ctcaggtagt tctttggtgt attcaccaaa aagtccatcg gtaatttcaa
     1201 gatagcctgc atgtttgaca cctgacgcta aaaagaattt gtcagcatag ataaaagttc
     1261 tcattctatt ctctcccttt gtttttctac ctctaaagta ctcttattta gagaagaagt
     1321 caagaatggt ctacaccatt tacaaatttt ttgaaatttg tttcacagct tgtgctaagc
     1381 cttcatagaa tgctgctctt tctggttctt ctttacgctt gtatattaag cttttaagca
     1441 caaataaatc attgaggtaa tagtagctat tcttctcttg agcccaatag attccttgat
     1501 tcacctgttc taacgcttcg tcgatttcat tttgatggaa taagaaattt ccataattat
     1561 aaaaaatttg cgaaaattca ctttttgatc gttcatcagc tgattgatgc agcagttgga
     1621 tgcttcgact caaatagtag cgtgcttcag ccgtttttcc tgccacacca tatatttttc
     1681 cgatacaact aatcagttgt atttctgtgt cagaaacatg gattctttct ttttggctag
     1741 agtagcttaa tgcttctttc aaataataaa gggactgaga gatattttga cgcaacgtga
     1801 attcgcaaac accgagataa taataatagc gttgaaagtc agttgcttga tacagatttt
     1861 cagaaatatc agaagatttt agtacttgtt ctaacttccg ataatcacgt ttttggaaac
     1921 aactatccaa cagttcaaat aatttatcgt ttgtccgagt agtttttcga gagagattca
     1981 tcacatgatc aatcgttacc cctagccgtt gacaaatctg catcatcacc aatacattcg
     2041 gcagttcctc attattttcg atccgactta atacactttg tgaacaaata tcatgcgaaa
     2101 gcattttttg cgtcattttt tgttcttttc gaatctcttt aatgatcgtt ccaaaggact
     2161 cgattaacgt ttccataagt atcctcccca aaatatgcgt attcgcattc tattcgtatt
     2221 ttactttagg aagtcgcaaa cttcaagaaa agacttgcaa ctaaataata tactttagtt
     2281 atttaagaaa actccactag aaagagagcc tcagtgtgtt tgtctgtggc cctcctactg
     2341 aaaaatttgg tttttaaaat catttttggc gataggttgc taggaattct ctcattttct
     2401 tagctgtttg tttcaaatca tccattttag gaagataaac gattcgaaaa tgatctggct
     2461 ggttccaatt aaatccacca ccatgtacaa gtagaatatg atgttcatgt aaaaagtcca
     2521 aaacgaattt ttcatcatcc aaaatattga atcgctttgt atcaattttt gggaatatat
     2581 aaaaagcagc ttttggtttt acggctgaaa gaccaggaat atcattgatt gcattataga
     2641 tatattctct ttgttcatag atccttccgc ctggcaggag cagctcatcg acactttgat
     2701 aaccgcctag cgcggtttgg ataatttgct gagacaatac attggaacac aaacgcatgg
     2761 aggacaacat attcagccct tctatatagc ctttgacgtg tgacttatct ccacttagga
     2821 ccatccagcc tactcgaaat cctgctacac gatgagattt ggatagaccg ttcagcgtaa
     2881 caacgaacaa atcaggcgct aatgtagcaa tcggaatatg ttctagacca tccatcacta
     2941 agcgatcata gatttcgtcg gaataaataa tcaggttatt ttgtcgagct acttcaacga
     3001 tttcttctaa taattctttt ggataaagtg ccccagtagg attattagga ttaatgataa
     3061 caatagcttt tgtccgactc gttatttttg atttgatatc atcaatatca ggataccatt
     3121 ctgcctcttc atcgcaaata taatgaacag gtgtgcctcc agctaatgca atagaagccg
     3181 tccacaacgg atagtccggc attggaacca gtacttcatc tccattgtcc agcaacccct
     3241 gcatacacat cgtgatcaat tcgctcactc cgttgccggt gtagatatca ttgatcgtca
     3301 cattcggaaa atgtttcagt tggcaatatt gctcaattgc ttttctagca gaaaagatcc
     3361 ccttggaatc tgagtagcct tctgagtcac gggcattcat gatcaaatca cgaatgactt
     3421 cgtttggtgc ttcaaatcca aaaggtgcgg gatttcccgt gttcaatttt aaaatactaa
     3481 tgccctcttc ttgcatccgc tccgcttctt ctagaacggg accgcgaaca tcgtaactga
     3541 caccttctaa tttgttggat ttttcaaatt ctctcatcac ttagccaatc cctcatttca
     3601 aaaagttaga actttccaaa ttttttgtta tttactattt caatatcata ctccatccta
     3661 gaaaattttg ccacttattt aggaaaaacg taagtattaa aaaaacacaa acaagcgttg
     3721 agaacttaat tgtcatgata gtcattccat agattcgctg cccaatccat tgcaattcca
     3781 caaatgattc ctagcataaa accaagcaaa aaacgtccga atgcaagtcc aatcaataca
     3841 cctaagatca ttcccagtcc tgaaaattct ccgtcatatt tctccatctt aataagtcct
     3901 cccatttttg agcttgacaa ctatgtaaaa cctcgctatc attagtgtgt tattattacg
     3961 cagatgtgtt ggaattggca gacaagcatg attgagggtc atgtgagcgt tagctcgtgt
     4021 gggttcgagt cccatcatct gcactacaac tcgtgaagtt aattttgctt cacgagtttt
     4081 tttgtttgaa cgtttcttta tgccattata tacatatcac tgtatccttt acaaaaagaa
     4141 cgtacaatca tgtaaacagc ctgaggtgag tatatgaagg tcggaaacaa gctactcgta
     4201 gaaacttgca agtgttaaaa caattaatcg aaaaacgagt aaaatccctc acctaatact
     4261 aaagcgaggg attttttgta tattatctgt ttatcaccgt tattataaag gtacaaatac
     4321 caagcacggt taatccaaat tgcataaatt catttttttg tacactcatg cttttcatta
     4381 gctctttaac tgccattagt actaagatgg cgataacaac ataaagtata tagtacgtcc
     4441 gcattccgga agcccatact gtgggagaaa atcccataat taaccttgaa caaaatccca
     4501 ttatcatcaa aataactaaa aaaatagaag ttttcttatt gtcaaaactt aaataaattc
     4561 caacaattaa acatagtaat aatgccaaga ctactaaagt agctatccaa gtacctggat
     4621 aaaaaagtga cagtttcgtt cctaactctg taaagagatt attcaggtta ctactactcc
     4681 aaatcattgc ccttttattt ccattgacgt aagtaaagct ttgacccatt gtattaccaa
     4741 aataaataat caggtttaag aaaaacggta atgcagtcaa tatacgcaca taatagtttt
     4801 gacatttcct atatgttaga aggaaaatta agaaaaatag caataaaaat aagatattca
     4861 tgtctaaaaa aaacggcttt ccaaatgatg aaatacctaa atctaactta ttaagaaagt
     4921 tgaaattttt atattcagga aaccatttat taatttcatg tgcagcacgt aatgcattcc
     4981 ctggagttgt caaagagaaa attaattctg ctaagcttat tattgaaaat actgataact
     5041 tataattata tcgtccattg acaatcaaat ataaactaac tatacttgtt agaacaaaaa
     5101 aacaggcgtt gacttgttct tgattagtta aaaatatcaa taaaggaata cttacccaat
     5161 atatttttct atttatttct tctcctctta agagttgaaa aaacggataa aaagttagta
     5221 aactaaatgc tactggccac tgatagttca aggtggttgc tctccaaccg gtttccccca
     5281 ttactgtcaa tggtattaaa cagtatatag agcaaaccaa taataaattt ttaacattta
     5341 ttttctcaaa aacat
//
LOCUS       DADVXB010000160         5251 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.166, whole genome shotgun sequence.
ACCESSION   DADVXB010000160 DADVXB010000000
VERSION     DADVXB010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.166"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..676)
                     /locus_tag="KB902_002492"
     CDS             complement(<1..676)
                     /locus_tag="KB902_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809263.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEK"
     gene            complement(682..1755)
                     /locus_tag="KB902_002493"
     CDS             complement(682..1755)
                     /locus_tag="KB902_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6809264.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            1977..2651
                     /locus_tag="KB902_002494"
     CDS             1977..2651
                     /locus_tag="KB902_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6809265.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            2656..3996
                     /locus_tag="KB902_002495"
     CDS             2656..3996
                     /locus_tag="KB902_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6809266.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(4145..5131)
                     /locus_tag="KB902_002496"
     CDS             complement(4145..5131)
                     /locus_tag="KB902_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBB6809267.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         1603 a          993 c          929 g         1726 t
ORIGIN      
        1 ttttctcttc ttctgtcaag tacccatctt ccattcgata aacgcgatca ctccattgaa
       61 tcatacggac atcatgagta accataatag tcgctttttg tttctcatga gcttctttaa
      121 ctagtaattt gacgacttca tatgcatgat ctgtatccaa actagctgtt ggttcgtctg
      181 ctaagatcaa gcttggctca ttatataaag cgcgagcaat tgccactctc tgtctttctc
      241 caccagaaag gtctttagga taactatttt taagtgactg gatatctaaa gattgcagca
      301 aggaatcgat ttttgttgaa tcttcttttt ttgaagtaac ttggtcaact agttcaaatt
      361 gttcctttac cgttaaaaaa ggaatcaaat tagagctttg gagaataaat cctatttctt
      421 taaagcgtaa atctgctcgt tttttttctg gaagctcagt tagtgagtga ccgttgatca
      481 ctatttctcc ggaagtcggt gtttgcaatc ctcctgaaat ggtaaggaaa gtacttttac
      541 ctgaaccaga aggaccaatg atgctgacga attctccttc ctttacataa aaatcaattg
      601 ctttcaaagc tgagaccttt gtatgaccag aaccaaatgt tttggtaact tttttcatcg
      661 ttaatatttt tttcattttt attaacctcc tattgctgta attgggtcta ctttggttat
      721 cgtacgtatc gaaaacaatc cgcctagcat tgcgacaatg atcaaaatcc cactatatag
      781 caaccattgt gaccaaaaaa cagcaaaagg catcgcgctt ggtaaaatca gactagtcaa
      841 ataagcaaac aaaagagcaa gcagaacgcc taccacccca acaataaagg actgtgctac
      901 taaagattta gcgatgaaga aatttttgat cccttgtgct ttcattactc caaaaatagc
      961 agtcttctga agtgtcatca cgtacatgaa aataccgacc acggcagcaa ccactaagaa
     1021 caaaaagtat atcatcgcat ttaaggtcat attttgggca gaatagccag gaatactttc
     1081 aatgaatgtc ccaatagtta ataactgtag acccttcgat gctttttctt tcgaaatttt
     1141 agctgaatcc tttattacga tcccattgat cggctgttct tcttcagaag caaacggctg
     1201 ttgtccatac ttcaaagcag tccacgtatc tagggacgca tagatgacgg gagaaactgt
     1261 gtaataagtt tcaggaaaga taccgacaat cgtcaaagga tcgtcgtaac tgccaatttt
     1321 gatcgtatct ccaattttat agcctgaatc agccagattt tgagagatga tgatttcatt
     1381 ctttgtttta aattcatgcc ctttcgtgag ttttggtaat aaaaatgctt ctttcgttgt
     1441 gccgaaaact gtaacatttt ctttgttttt tcctttgatt gctccgctgt acaatccgat
     1501 tggtgctttc tctcctcctt caatgtattt cagatctcct cttgttaatt gtgaagctgc
     1561 aaatacttga tttgcatcct ccgacaaaac aatctcttgt gcgtcccaat catcgattgc
     1621 ttttttaaac tcttctgaaa gtccattcgc tagtcctgac aacatgaata cgacatacgc
     1681 aatcaagaac ataataccga cgatcaagcc atatcgtaat ttagaatagc gaatttcttt
     1741 gatagctaga aacatttgtt tttcctccct atgatagatt gatagtgaca aaatgtcact
     1801 tgttgaatag tgtaactcta aagtgacaat ttgtcacttg tgttgttttt ttcttatcaa
     1861 taaattgtct aagacatctt tcgataaaac cttaacatga gtcataaaaa atttatttaa
     1921 gccttattta tgctttccat gataaactaa agtgaccaaa tcaatgaggt gggaaaatga
     1981 ttaaactatt agtagtagaa gacgataaag tattatccaa taatataaaa gaaatactcg
     2041 ctgcaatcgg cgagataaca caagtttatg atggtagtga aggactgttc gagttggaaa
     2101 gtggagttta tgatcttgca atcttggatt tgatgatgcc ggaaatgaat ggatatgaag
     2161 tgttagcaaa aatacggaaa gaaaaaatac agactccagt attgattttg actgcaaaag
     2221 atagtttgga agataagatt gaaggatttg aacgaggtgc agatgattat ctaacaaaac
     2281 ctttctatcg agaagaactg atcatgcgcg tgaaagcatt attgaaacgc tcgctaggtc
     2341 tctttgatga aaatgttctg aagtataagg atatcagttg tgatttaaaa agcaatgaag
     2401 tcttgtataa agaacaagtt ttgcccatac aaggaaaaga gtttgaattg ctcgtttatt
     2461 ttttacaaaa taagggaatc attttgacaa aagagcagat atttgaccgg atctggggat
     2521 ttgattctga tacgacgatt acagttattg aagtttatat gagcaactta cgaaaacatc
     2581 tgcgaagtac tggattggat aaagaaatca aaaccttacg taatgtcggt tatatactgc
     2641 aaagggtgtg atgcaatgaa tggagatatt acacgaaagc aacgtagtcg cttttttgcg
     2701 acaaatgtag cagcatttgc ttttatcttt tttcttttgg gattcattac tttacagata
     2761 ttaaaccaat ctgcatacag agaaacagat ctgtcattag agaaaataaa ttttgattct
     2821 cgaacagtac aattagagat acaaagatat cagcaaggcg atcccttttt aaacccgact
     2881 caaacggaac aaaacagaac aaacatggaa cagccattaa tggaaccatc aaatgaccgt
     2941 tttaacactc aagtgatctt gtggtctaaa aatggtgaga tattgaataa agcagctatt
     3001 ggtgggcgtt tcaaccaaat caaagaatta aaaatggata cgaaaaatct gaataccatc
     3061 caaaatattg aattaaatga agacagtggc tcatctgccc tctctttccg ttcgattacg
     3121 aaaaaagcgg agacgaatca agatggcgtt gcctacatcc aaattttaga aaatacaaat
     3181 caaatcaaga attcattagc gacttttcgc acgattatga ttttgtgtat gattgttttt
     3241 tggattctct ctattggtat cagttattac ttgtctagtc taagcatgcg ccctattatt
     3301 ctttcttgga gaagacaaaa agaatttgtt gagaatgctt ctcatgaatt gcgcacaccg
     3361 ttaacgatta ttcaaaatag tttggaacat ctttttacca agcctaatca tactattatt
     3421 gaagaatccg aaagcatcgc tcaagcattg tcagagacga ggcgcctcac tggattgact
     3481 tcggatttgc tgacaatcgc tcggaatgat tctgatcagc agctgctttc aaagcaaatg
     3541 atcaatacac aagaatatat cgaacaactt gttaaaccat ttcaagagat ggccatcata
     3601 gatggaaaag agtttattct ccataacgat gcaacattag aagtaccaat tgatgaaaaa
     3661 aaaatccatc aagttttggt tattttgctg gataatgcat taaaatatac gaatccagaa
     3721 gataagatca ttttggattc atctgttaac cataaagaat ggctgattca cgtaaagaat
     3781 actggccctt ctatcagtga agaagatcaa gcaaggattt ttgatcgatt ttatcgggaa
     3841 gatcaatctc gggcgaaaga gactggcgga tacgggcttg gcttggcaat tgcaaaacag
     3901 gtaatcgaac agcatcatgg acagatttct gtatccaatt atcttccaca aggagtcgat
     3961 tttaaagtcc aattgccgtt gaagcctaaa aaataatgct tatccctaaa aaagggctgt
     4021 gacaaaaatc ttgtcacagc ccttttttgt tgcgaataaa cggtgttcca gaagtagctt
     4081 cttcggaaat aagccgaaat ttctttaagc tgaccacttc tgtcacaacc tctttagctt
     4141 acgcttacga ttttttattg cggtcttcaa tgtgtacatc accgcttgtg tcaatatcca
     4201 attcttctcg gctaacatct tctgtcactt tttcaacatc ttcatgttct tctttatgaa
     4261 tcccaacttc ttcacgaata actgtatgtt tgcttacatc tacttgctct tctttgattg
     4321 ggatagtaat cgtgtcatct tccaattttt cgtctgttcc ctgtgaagat tgatctgtta
     4381 ctggtttgcg ttcgatgacg atttcttcac gtttgaccgg tacttctacc gtttcagtat
     4441 cgttgaccac atgtttgtgg atgtcgactt ctccagttgt cacatcatgt gtatttacat
     4501 ctaatttttc ttcttttagt tgaattgtat catcatctag atttggtttg cgatcgatgt
     4561 cttcagtctt gcttgtaccc attgtatcag tctcgccagg tacgtccatc ggatcagttc
     4621 ctggtgtcat attcaatgga tccgttgtat tttgaaagcc tgtcgtgcca cctacgtcca
     4681 ttggatctgt tccagtgcca gtttctaatc cagtccccat tgtgcttgct gggctaacag
     4741 tatcttgtgt atccattgta tcttctgttg tttctggctg acgatagcct tttactgtga
     4801 tgacaaattt tccatcagaa atatctcctc tatattgata taaaggatca ttttctggtg
     4861 tagccgtctc agaatcatag gtatcaaaag aaaaagtatc ttttattttt tcccataaag
     4921 aacggtcttc ttcaccatcc atccgatttt catctgtttc aacatctata ccagacaatc
     4981 cgtcaaatcc tagtctagat gctgcttcat cagtagtata aataacgata tcatctcgtt
     5041 catacccttc gttacgcaac cgttcaatta ctgataatgc ttcttccctc gtactatagc
     5101 ttccgatgac cgttaaattt ttctcttcca tgtaaattcc tcctagcaaa tagatttatg
     5161 attggtatat tgttacttat aaatttattc tataggagac gattgttttc tacaaatatt
     5221 tagattggaa tttgattaaa acaatttaat t
//
LOCUS       DADVXB010000161         5203 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.167, whole genome shotgun sequence.
ACCESSION   DADVXB010000161 DADVXB010000000
VERSION     DADVXB010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.167"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            44..1333
                     /locus_tag="KB902_002497"
     CDS             44..1333
                     /locus_tag="KB902_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6809268.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(1459..2538)
                     /locus_tag="KB902_002498"
     CDS             complement(1459..2538)
                     /locus_tag="KB902_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6809269.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2647..3087)
                     /locus_tag="KB902_002499"
     CDS             complement(2647..3087)
                     /locus_tag="KB902_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6809270.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3144..3554)
                     /locus_tag="KB902_002500"
     CDS             complement(3144..3554)
                     /locus_tag="KB902_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6809271.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(3735..4169)
                     /locus_tag="KB902_002501"
     CDS             complement(3735..4169)
                     /locus_tag="KB902_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6809272.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(4269..5117)
                     /locus_tag="KB902_002502"
     CDS             complement(4269..5117)
                     /locus_tag="KB902_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6809273.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         1914 a         1004 c          872 g         1413 t
ORIGIN      
        1 atcttatttc ttgcatacaa aaaaatcaag gagtgagaga gttatgagat attcaaccat
       61 cttaatatca acatttgcag ccttaagctt atcgcttact ataaatcaga cagtccacac
      121 agaggagata gaaacagcca aatggacaga aaccaagtgg gccaacgtca atcgaattac
      181 ctttcaggat gaattttcat ccttcaattc aggagtcgca aaattaagaa aaggacaaac
      241 agcgaccatc aaagcaaaaa ttgactattc aggagactta gcacctatac tacaatcagc
      301 tgttacattt gagaatgttg atcccgcttt gtcgattggc tatgacgaga acactttgac
      361 tatccaacac aagcaagcga tatttacctt caccgttaca ttaaatcagg acttgttaaa
      421 accagcgctt tttactgtca aggtatcaga tggactaccg aacgatcatc atcatttaac
      481 gccgtatagt cagcggcaga caattgagca agattcagct atcgactcag gaggagatct
      541 tgttgaagaa ccaacagata aaccagaaaa tgaaaataag ccagaagtac cgcctacaga
      601 aaatccagac ggagaacaga aaccggaaat agaacctgga gaagaacccg atacagaaac
      661 tcaaccagag ccagacaatg aatcaaaacc tgaaataacc cctggagaaa aaccagatgt
      721 agacccagaa gaaaaaccgg atgtgactcc agaaccagat acggattctg gaaaccaaac
      781 agtaccggaa acaaatccag acacagataa tgaaactgaa aatccagaaa aaccagaggc
      841 agccccagaa gaaaaaccag atgtaactcc agaaccagat acggattctg gaaaccaaac
      901 agtaccggaa acaaatccag acacagataa tgaaactgaa aatccagaaa aactagaggt
      961 agatccagaa gaaaaaccag atgtgactcc agaaccagat acggacgcaa gagaccaagg
     1021 aataccagaa aaaataaaca aaaaaacaat tcaagaggat ggaaaaaaag agagtaaaaa
     1081 atcaaatcta gcaattctaa aaataaatga agagcagctg aataaaaaat cacgaatatt
     1141 tgatagcgcc caatcagctg aaaccttaaa aagtagcaag gatacaacct ttgctagtcc
     1201 tgaaacgaaa aataaacagc taccaaaatc cggagagtca caaaacaaag ttatactgtg
     1261 gagcggaatc attctattaa gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa
     1321 cagatctctc taacatttga ataatgtctg tgaacgcatt tttcaaataa aaagaaatat
     1381 ccagaaaacg accccaaaat accagattga aatctgatat ttggggtcgt tcatacttta
     1441 tctttcttca tatttatttt aagggatatc tgtttctttt ggaagatggt tcgggatctt
     1501 tttcactttc aatacatcta aaaagaaggt aaagatcgga atgccgacaa tcaagcccca
     1561 aacgccaaag aaccgttcgc taacaagtaa gaccacaaat gtataaaaaa tcggcagttc
     1621 tgttttgctg gacatcaact tcggattcag cacataagac tcaattagat ggacaatcaa
     1681 aatcgtaatc aggatataaa caacatctcg gatgcctcct tgggaataag ctatgaaaga
     1741 tagaggaata caagaaatga taacacctgc tactgggatc agacttaaaa tgaaaatcat
     1801 gatcgctaaa ctcagcagct gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa
     1861 cgtgtttaaa agagcgataa caaattgagc ttctaatacc aaaccaaatg tattgacaaa
     1921 cttatcggca aaatagtaaa tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa
     1981 tcttgagaat acaattgttt ttttcttttc aatcataaaa aagaaactta agatgaatga
     2041 catagcaaac gccactgcca tttttcctat atcctgtaaa tagccaagcg caatcgaagc
     2101 gccattttga agctgttcaa aaaaatcgtt tcgctcaata taagtatgga tatattgtaa
     2161 aacaggatct gcatcttttg gctgatgctc gtaaaaatca ataacggact ggatcatatc
     2221 aaatgtttga tgaataagca tcgggatata ctttgtgaat gccagataga taaggtaaac
     2281 gatcagtgta taaatcatga tagctaaaac acctgtaggg attcggacaa atcgctgaat
     2341 gatttgaaca agatgaatca tcaaataagt aaagataaat gtgagcaaaa tggttgtaat
     2401 catacttcta actaagaaaa gaacaaaaac gacaaataat aaaacagtga gacggcgtat
     2461 tttttcattc gccaaaaaac gctgataaac ggtcaaatcg acaacctcca aataacaaaa
     2521 aataaacacg ttattcatta tatgatggaa tatgaaaata agaaagagaa agagcaaaaa
     2581 gaaaaaccgc taaatgacgt tatcttatga gttggttttc ctcataaaat cgttcatcta
     2641 gcagtttcag ccctttttct ggtcttgatg aaaattatct agcatttttc gggtcagatg
     2701 ttgcagtgta tccaattctt cctgttcaag tggaagataa gacttgatct tttgtggaat
     2761 accttctgct tgtttttgca acgcagcacc ttgaggagtc agcgtaacat ttacgattct
     2821 ttcatcaccc gtttcacgct gacgattaat ataatttttt tctgctaact tttttagtaa
     2881 gggagtcagc gtaccagaat ccagacacaa atcatttcct agctctttca ctgaagtctt
     2941 tttcttttcc cataaaacta acatcacaag atactgggta taggtaagat tcagcggctt
     3001 gaggagggaa gtgtagtgtc taatgatttc cttagaggcg gcatataaag gaaaacatac
     3061 ttgattaact aaatatagat cttccatttt tccacctccg ctgttttact atagtgtatc
     3121 atagcggatt tacacaaaaa agtctattca ctaactgctt tcagagtaac ttctatattt
     3181 ccagctgtag cttttgaata cggacacact ttatgcgctg cctctaataa ttcttgcgtt
     3241 tcttccagag aaagaccttc gatagatcct tcaatctcta cacctaagac aaagctcgtt
     3301 tcactttctg aataaaggga aacttgtgca ctgacagtag aagccccaga gatatttttt
     3361 tgctgtttga tcaattctaa tgcactgtta aaacatgcac tgaaaccagc tgcaaacaat
     3421 tgttcagggt tggttgcatt ttcgacgcgt ttaccaggag ctgcaatatt caattcgaat
     3481 gtacgatcgg gattatgaac ttctccagag cgtccgcctg tgttgatcat tttcgtagaa
     3541 tacatttttt tcataaaatt accaccttta attatatttt atacaattga attttacaca
     3601 atataattgt ggaaagcaaa gaaatggatt ggcataagat aaataagaga aagcacatga
     3661 aacagacgcg ctttctcgaa tagcaaacat atacaaaaaa atatcagaga caaaaactaa
     3721 tctcatcata aacattacat atatttctca aaaagttgtt ttctttcttc aaaacttact
     3781 tcacgatgga cctgatgaag catccataaa taaccaaaag gatctctgaa cattgagtta
     3841 gtcacaccaa agtccatcat ttctgtcatt tcttgaatct ctacacagcc atttcgtaat
     3901 gctttattat gtgtgtcctc gatatcagag acgatgatat tgaaccagat cgtatttgga
     3961 tgttcagcag taggagcagt caaaccaaga gacgtgtttt catccagcat atggaatctc
     4021 gtgccataca aggtaaaaat gacttcatta ttgcctctag ggtaatctgt tgcctcaatc
     4081 agttgtattt catcaaagat tgtttgatac agttctagtg ctttcaaact atcatttaat
     4141 acaaaatcta tttccgttcc tttatgcata aagatctcct ctccttttca gtcgaacagt
     4201 tactagattc ttttattata ccagttaaag aaaacgcatt caaaaaaata gcggatttac
     4261 ttaccaactc attcgattgg atgataagta aatccgcgtc ccattacttc tgctacgctg
     4321 ctgacaatga caaaggcact tggatcgatt tcttctatca atggtttcat tcgggaaaat
     4381 tcatgatcag tcacaacgat caataaaacc tcttttgact ttcgattata cccgcctttt
     4441 gcctctagca gggtaaggcc acgtccaatc tcagcactta agcgaaggcg gatgtcttcc
     4501 aaataatgtt cactcatgac cataacagat ttctttcgat tgatacctgt ttcgatataa
     4561 gtcatgacaa ttgaagtgat tgcaatagat aaaatagcat aaagaaactc ttctattcca
     4621 aaaacaaaca gattaagaga aacaacgaat gcgtctgtaa aaaataagcc aatcgaagta
     4681 ttcaagtgga aatatttttt aaaaatgagg ggagggatcg tcgtaccgcc gctagaagag
     4741 ttgtttttat ataaaatcgc aactcctaaa gcaaaaatcg cacttccaaa aatgacagac
     4801 aacaaccgat ctgaagtaat cattgtttct ggaactattg caatgattaa aggaaaaaac
     4861 aagcttccga aaagtacttt aaaaaagggt tttttaccta aaaatagaag agctagtacc
     4921 aacataacga tattcaacac taaaataact atagctcggt caaatcctaa aacagcttcc
     4981 agtaatattc ctagaccgct gacacctcca gcagcaatat gatgaggccc taaaaacata
     5041 ttgatagcga ctcctaatat gaagagggca aaaataatct taatgtatgt ccatataaat
     5101 tgtctcgttt ctttcattta tccacttcct taattcatta ataatactct tatcttatta
     5161 taacttactt ttcaccttaa gttaacttta attaataaaa aaa
//
LOCUS       DADVXB010000162         5173 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.168, whole genome shotgun sequence.
ACCESSION   DADVXB010000162 DADVXB010000000
VERSION     DADVXB010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.168"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            123..998
                     /locus_tag="KB902_002503"
     CDS             123..998
                     /locus_tag="KB902_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809274.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1102..1866
                     /locus_tag="KB902_002504"
     CDS             1102..1866
                     /locus_tag="KB902_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBB6809275.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1853..3295
                     /locus_tag="KB902_002505"
     CDS             1853..3295
                     /locus_tag="KB902_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6809276.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3306..4637
                     /locus_tag="KB902_002506"
     CDS             3306..4637
                     /locus_tag="KB902_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBB6809277.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            4650..5108
                     /locus_tag="KB902_002507"
     CDS             4650..5108
                     /locus_tag="KB902_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6809278.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EETLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1756 a          753 c         1097 g         1567 t
ORIGIN      
        1 atgtgttaaa ctatttttgt aaattatgta gggtgctact attcaattag gcacgaccta
       61 agaaagggtt ctttcttagg tcgttttttg tctttaaaaa ttgtttggag acaaaaatat
      121 gtatgaagga gtctgcaagt tgttttgttt tatcatatag aggaggtgaa ttaacggtgt
      181 atgtgatgaa aaagctgaat cataatgctg tattgatcga tgacgatgga atagaaaaaa
      241 ttgcgatggg gaaagggatt ggcttttctg ctaaagtgag taagccattt gatgttgagg
      301 atgctgacaa attatttgta ttagattcta aagaaaagat caaacgattc agtgagatag
      361 tctcgcagat tccaatcgaa tttatggatt ttgcggaaga agtgattgaa ctgataacag
      421 ctaggatctc ctctccatta gattcaaata tctatattac attgacagat catatttatt
      481 ttgctattca acgaaaaaga gaagatagag atgtcacagc aattatgttg ccagaaatga
      541 gattccttta tccaaatgaa tatgatatag cagtagaagt ggtcgagcga atcaatcatc
      601 gatatcaaac cgagttaggg tcaaatgaag taggattcat cactatgcat atcattaatg
      661 ctgagctagg agagcctaat agtttaaaga gcttaaaaat agtagaaatg acgaccacga
      721 ttttgtccca tctagaaaaa tcctattcaa acgtttatga taaagaatca ctgacttatc
      781 atcgcttaat ggttcatatc aaattcctgg ttaaacgctt gatttatcag gaagaaacgc
      841 cagtagaaaa tattggtttt tttactgaaa catttaaaca tagcaaagcg tattgtacag
      901 cactaaagat taaagatatc atcgaacagc aatttcaact tgccattcaa gaaaatgaaa
      961 tcatctattt ggcaattcat ctagcaagaa tctattaaaa taagggcgta actatctata
     1021 ggcgcaacca aatgacacat agtaaatgga ctatgattat ttggttgcgc ctattttagt
     1081 agaaaaaaga aggagaatga aatgggaaaa gtgattttta attcggatga ttttggctat
     1141 agccatggtg tgaattatgg gattatggat gcttatcagc gaggaatttt gacatcaact
     1201 acattgatgg caaatatgcc gggtttcgag catgctgtga aactaagaaa ggaaatgcct
     1261 aggctaggtg taggagtcca tttaacattg acgtgtggca aaccactcct caaaactgtc
     1321 gatactctta tcgaaagcgg agagttcaga tccttatctt attatcagca tccatttaac
     1381 attgacaaag atcaactgta tcaggaatgg aatgctcaga ttcaaaaaat ttatcatgcg
     1441 gggatcatac caactcattt agacagtcat catcatactc atactttgga tgaaaatcag
     1501 gaggtagttg ttacattagc aaaaaaatat gatttgccgg ttcggagcaa ctttgaacga
     1561 aaagatgaag ttcgtcatgt cgattatttt gagccttgtt tcgatgtcgt aggagaaact
     1621 gatgaaaaaa aacgacaaat caatacgagt gtggaagaat atttggcaag tttactcatg
     1681 atattgagag aagataaaac gatcgaagtc atgtgtcacg cagcgtattt ggatcaggaa
     1741 ttgttaaatg gttcaagttt tgtgtatcct cgtacccacc aagtcgaatt tttaattcat
     1801 tcagcatttg ctcaaaaagt gaaaaatgat cctttgattg agttagtaac atatgaggat
     1861 atttaataga ggaggaataa aaatgaatgt taaatcaaat gtgcagaagc ttggaagagc
     1921 gatgctactt ccagttgcag cgatgccatt agcgggattg atcatgcgtt tatcagctga
     1981 cgatatgctg aacatcccag taattggtgc agctggaaat gccgtttttg gaaacttgga
     2041 tatcttattt gctataggag ttgcaatcgg ttttgtcaaa aataaggaca aaggaatacc
     2101 tgcacttact ggttttttag cgattgctac cttgaaaaaa ggcttagaaa ttatggaccc
     2161 agaagtgaat atggggattt ttggtggaat tatttccggt ttagtagcgg catggacgta
     2221 taatcgcttt aaagaacaaa aattaccagt agttttttct tattttgcgg gcgaaaaatt
     2281 cccattgact atggtgatga ttctacaaac aatcgcagct gtttttttgg gctttatctg
     2341 gccgctcatc caaattggga ttgataattt tgcaaaactg ctcgttgata tgggagcatt
     2401 aggtgtgggg atatttatgt ttttgaatcg tttgctgatc ccctttggac tgcaccatgt
     2461 gttgaatacg tatatttatt acgatttagg aagctataca tctcctagca aggaagtttt
     2521 cagaggagag atgacacgct ttatcaacgg agatcctcag gctggactgt ttttatcagg
     2581 tttttttgta gtaatgatgt ttggtatacc agctatatgt ctagctatct ataaagcagc
     2641 ttataaagaa aataaagaga tggtcaaagg aatcatggga agcggtgcag gaacttcatt
     2701 tattgcaaat atcactgagc ctgttgaatt tagtttcatg tttctttctc ctatgttgta
     2761 cgtgatccat gcactttttg ccggtttagc agggattgtc tgttacttat tcaatatacg
     2821 aattggtttt acattcggag catgtattgt tgattatctc atcaattttc gaatcgctac
     2881 caatgctatt ttgattcttc caatcggaat tttctttttt gccttgtatt acgttacttt
     2941 ttattatttg atcaataaga gaaacattca gacattagga cgtgaagcta aggcagagtt
     3001 tggcaatgaa gtaaccttag aagaaacaga gttagggtta gcaagtaaaa attatgaata
     3061 tatggcaaca aaaatgctac aagcgtttgg aggaaaagcc aatatcctgg atgtctatag
     3121 ttgtaataca cgcctacggg tagaggtagt ggatcccacc atggtcgagg aacagcgaat
     3181 caagcaatta gggataagcg ggatcattaa accaactgaa aaaaattatc aaattatcat
     3241 cggcttagaa gtgacttatg ttatggcaga attcaataaa ttattagaag aatagaaagg
     3301 aaaagatgat gatgaaaaaa cagattatca ctatagctgg aggcgggagt acgtatacac
     3361 caggaatcgt tcaagccatt ttgaacaatg aaaaacggtt gccattatct gaaatacgtt
     3421 tatatgatat tgatgaagaa agaaatatgg atatgtactt gattgttaaa tttatgctga
     3481 aaagaaaagg tttttcaaat attcgcattc gtgcaacgga tgatccaaag cttgctttta
     3541 caggatgcga ttttgttttc tcacaaattc gtgttggagg attggagatg cgagaaaagg
     3601 acgaaaagat tccacttaaa catggattag taggacaaga aacgtgtgga ctcggaggat
     3661 ttgcttatgg gatgcgctca atcaaaggtt tattggaaat tgtcgatcat atacaagact
     3721 atgcccccaa agcatggatt ttgaattata caaatccaga gtcgatcgtt tctgaagctg
     3781 ttcgtcgtaa atatccgaat gtaaaaatga ttaatgcctg tgatatgact atttcaattg
     3841 aagaaacgat tgcagtgaat tacggttatg atcgtaagaa ttggatcgtt acgtattatg
     3901 gtttaaacca ctttggctgg tatacatcga tttatgataa agaattgcaa cgagaaatta
     3961 tgccagagat tattgaaaaa ctaataacaa aagaaatgca agtcgccgat tttaatatag
     4021 gagataaaac ttggcaaaaa acctttcaaa tgatgtcagt catcacgaaa aattttccaa
     4081 gtaatatccc gaataattac ttagagtatt acttatatcc tgatatggtc gttgagcata
     4141 ctgacaaaga gtatacacgt gctaatatgg tcatggatgg acgagagaaa aataccaaag
     4201 aaatggctga taaaatacgc cgcggtattg tggaagaagt attgaacttt aattttgggg
     4261 agcatggaca atatatcgtc gatatagcta tttccttgtt gaatgatgat cgtcgtcgct
     4321 ttatgctaat cgttcctaat caaggggcga ttccgaatct acggtcagat gcagttgttg
     4381 aaataccggc atatgttggt gcaactggtg tggagccaat tacactaaga aaaccaatca
     4441 gtgattttca taaaggattg atggaggcac aagttgcagt agagaagtta ctagtagatg
     4501 cttactttga aggttcttat caaaaagctt tacaagcatt tacattgaat caaaccgtac
     4561 caaatgccag agtcgcaaaa aaaatactag atgaaatgat caaagtaaac aaaaaatatt
     4621 ggccagcatt aaagtagagg tgataaaaag tgcatttctt taaaacaaga aacattctaa
     4681 aagctgtagc tagtggtcaa attattccat taacagcagt aaaagacgag gtcttttctt
     4741 caaaaatgat aggagttgga tacgctataa cgaatcatga tggatatatc catgcgccag
     4801 ttaaaggaat aatcgataat atatttccta cccgacatgc cataacgatc gaaagtgaat
     4861 ctggcagaaa aatactgatc catatgggtt tagatacagt tgaactcgaa ggaagtccgt
     4921 ttcagatacg ggttgaaagt aaccaggagg taaaagaaga gacactgtta gctattatag
     4981 atttgaagaa gttggagcaa gcacaaaaag atacggtgat cattgtagtt tctccaggca
     5041 tttttgaagg aaatttatta aaacaaaacc aagaagtaaa gattaaagat agttgttttg
     5101 aattttagtg tacgatgaaa aaagttaaat agggtgatat ttatgggtga atttacaaaa
     5161 tttttttgaa atg
//
LOCUS       DADVXB010000163         4964 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.169, whole genome shotgun sequence.
ACCESSION   DADVXB010000163 DADVXB010000000
VERSION     DADVXB010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.169"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(144..1013)
                     /locus_tag="KB902_002508"
     CDS             complement(144..1013)
                     /locus_tag="KB902_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6809279.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(1033..2154)
                     /locus_tag="KB902_002509"
     CDS             complement(1033..2154)
                     /locus_tag="KB902_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6809280.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(2156..2551)
                     /locus_tag="KB902_002510"
     CDS             complement(2156..2551)
                     /locus_tag="KB902_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6809281.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(2570..3376)
                     /locus_tag="KB902_002511"
     CDS             complement(2570..3376)
                     /locus_tag="KB902_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6809282.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(3369..4157)
                     /locus_tag="KB902_002512"
     CDS             complement(3369..4157)
                     /locus_tag="KB902_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6809283.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(4171..4647)
                     /locus_tag="KB902_002513"
     CDS             complement(4171..4647)
                     /locus_tag="KB902_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6809284.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(4719..>4964)
                     /locus_tag="KB902_002514"
     CDS             complement(4719..>4964)
                     /locus_tag="KB902_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809285.1"
                     /translation="DLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEF
                     QKFQTHFKQSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
BASE COUNT         1561 a         1081 c          729 g         1593 t
ORIGIN      
        1 ggataatttt tctcttaaaa aatatcatta tttgtggtat ggagctgggt atcatgagtg
       61 aatgatattg ctgaatacaa atagtccgac cacattaagt tgatcggact tcataagcat
      121 tttattgact aatacttttt tgcttaagaa ttgattctaa catcttttgc taaagttaag
      181 catcctatag ttcctgcatt atctgctaac ttaggtgtga caatgtattc ttcgatattt
      241 ggcgtatcga catagccgtt aattagttct aaaaaacgtc tttgtacttt ctttttcaga
      301 tgttcttgtt gcatgacacc accaccaaaa attataatat ctggtgaaag catcagggtc
      361 gtattacagg cacattgtgc aatataatcc gcctcgattt cccagaacgg atcttctata
      421 gaaagatctt gtcccttggt tcccgtacgc atctcgatag cgggtccaga tgccaaccct
      481 tcgagacaat catgatgaaa aggacaagta ccagagaaag tatctcctga atgtctctta
      541 actaacgtat gccccatttc tggatggcta aacccttcaa caaaaatccc atcttgtata
      601 gctcctccac caattccagt tccaacagtg taataaacaa cactggataa accttttcca
      661 tgacctgaaa catactcccc gtaacaagca gcattcacat cggttgtcca ggcaattgga
      721 atttcgaaat gcttattcaa cgttccaaca aaatcaaaat ttttccaggc agtttttgga
      781 gtagaggtga tatgtccata ggtctttgat tcacgatgga tatcaatcgg tccaaatgac
      841 cctactccaa tgctttctaa ttgttcttta tagtgattaa agaaatcaat taccaaactc
      901 attgtttcat tcggtgtagt tgtaggaaaa ctcactcttt ctaaaacctt taaatcatca
      961 ttgccaatgg cacaaacaaa tttagtccca cctgcttcta ttgagccata catttcttac
     1021 tccaccgtcc ttttatctag gaattcgttc ttccctgtct aatagttttt cgaaaaactc
     1081 atgtggttcc ttttggtacc aataggcaac agaagaaata tcgtcttgac gctcataaag
     1141 cttgatgtca tcatttccta gggtttggaa agtaacacgt aaattttctt tgaaactaat
     1201 ggggtcgggt aaatgccagc ggtacaaccc atgcatcggt aaagcatcat cgccaaaacc
     1261 atgaactgga tttggattag gttttccagc actaaaataa tcccgggtgt gatctctttt
     1321 agattgaaaa ggatagccca taaatagcgt attaaaattt tgagcatatg ccctttctcc
     1381 aaagttcttt ttatggaaag cccaagcgcc gccaaaataa tcttctgctc ctgtagatgt
     1441 tattgtaggg aaatcttcat ctccatctat ataaaactta aattctcctt ccccccacca
     1501 gtatctttcc aatgcgcaca aagcaaagta ggttcctaca taatacccag tgcctttgat
     1561 tccatcaata agggtgtaat cttttccttt tgtcgtgatg ggttcacggt tccatttagc
     1621 atgaaaatac atcgcatcat ccggtacttc agtcaatgca taattaaatg tataaaaaat
     1681 gtgcttaata aactcaggat gttcattcgt taaagtaatc ttagcttttt ttcgaaatgg
     1741 catctcaaaa tagcaattca tccctgatgt tggattcact acgattggta aggaattcac
     1801 ttcgcatctt gtcccaaacc cattacaaaa aaaatctcct aatggacttt ctacagaagg
     1861 agtggattca tcatcccaat aaatacgcaa aattaaatca cgtaagacga aactcccagc
     1921 gattgttttg tctgtcactg tcatccaaaa atgacgtaaa attccagggc cttccatttc
     1981 tgctaaagta attgtctctc cagcatttat cggaacagaa ggtgaccctt ttctcccaat
     2041 tcctagatga ctcgctgtca ttgccgcttt ccctttttca ccatttttat tttctggtga
     2101 aatagttcta ctttcctctc ccttgtggag ccatatatta tttaaacaat tcattttatt
     2161 cgtcctctat cctttcttca cttttttgat tattcatata gatgatttgt tgttgtgcct
     2221 ccgcaataat tgctccaata tctaaattat catttcctaa ctgcaaagcg attgacattg
     2281 ccaagggaag attcattcct gcaattacgt gcactctgtc agaaatatag gtaaaaaact
     2341 tttgatttac acttcctcca gccatgtcag ttaaaacaat tatttcgtct gtagtatcca
     2401 ctaactcttt aatttgttca tctatatcat caatttcttc gacatatgca cataagctac
     2461 taatttgatt atgcatacct gttaaaaact ctagtgtctc tttaaaaccc tcagctagta
     2521 ttgaatggct agcaatgatc aatcttctca taattcaaat ccttttcctt tacgctaata
     2581 ttccaaatgc agccataacc atcgcaaaaa caataacgag tagaatcaaa atggtcatac
     2641 tgattttttt cttactgagt agataatatg ctgcagcagt aataattact ggaattaatg
     2701 ttggtaaaat tttgtccaac attggttgga ttttcatact aacttcacca aaagtgaatt
     2761 taagtggcgt tgaaacactg ataactgaag caattaatga tccaactact gttagcccca
     2821 atactgaagc agcttcagtt aaataattaa tcttttcacc gtattcagta acaatcttca
     2881 ttccctgctt ataaccaaat tcaaagcctc tcattcggaa aaagaagatt accatgatta
     2941 aaatgaacca taaaaagatt cctacaggat tattttctaa agccatataa gccgcaattg
     3001 atcccatgat ggttgggatc atcgtcatca aaagagagtc cccaatacca gcaattggac
     3061 ccatcgtacc aactttaaag tcattaatcg catcttttgc ttctaatcct tgcttttcct
     3121 ccattgcaac acaagcacct aaaataatgg ctgccagcca aggctgtgta ttgtaatact
     3181 gaaagtgatt atttaaagct tcgatgtatt catcatcatc tttgtataat tttcttaaaa
     3241 taggtgacaa tgcgtaagtc acagatgcac cttgctgtgt ttgataatta aaggtacaaa
     3301 ctgacatcaa ccaacgatag ttcgctttcc taagatcctt tttcgttact tgatattttt
     3361 cgctcatttt attcatcctc cccaataaac ccaacatcag aagctcccgc agaagcagtg
     3421 atttgtgcat ctttttcagc tctatgatac acattaaatg ctaaagcgaa tcctatgatc
     3481 gccgctccaa taataggtac cttcaaaaaa gcggctaaga aaaatccaac aagtaaataa
     3541 ctaatgtatc gacctgtagg cataaagcgt aacaacatcg caataccaac agcaggcaac
     3601 atttttccgg ctaatgttag cccatccata aaccaattag gtaaaacatc caaaacgtaa
     3661 ttaacagcag actgtcctaa agtaacggca ataaatactg gaattgctgc agataaacca
     3721 aagaaaattg gccccaacca caaaacacta ttcattttct taaattctcg tttattcgca
     3781 tattcctgtg atttgcgaac aacaaaacca tttaagattt tgacaattac atctagttgc
     3841 acccctaaca tacctacagg tagtcctatt gctaatccgg cttctactcc aagctggcta
     3901 ccaaatgccg ttgcaataat tgcacacgtt ccatagtccg gtacagatga gccaccaaaa
     3961 ccggcaactc ctaatgacat caattgaact gtaccgccaa ctatcaaacc tgtttttata
     4021 tcacccatca aaattcctgt gaataatccc caaaaaactg cgtaatttac aaagatcatc
     4081 ggaatcccat aataatcaac atgtttaata aatgctaata tagtcagcat aataatttga
     4141 aaaatagtaa aatgcattat ccttactcct ttatcctaat tttgattgaa tttcctgtgc
     4201 cttatccgcc ggaacaaatt gtgtaacaat ttctacacca gaatccaaca attttttata
     4261 cgtgctgata ttttcatctg atgcataggc tctagaagat agctgtaatg cattatcttt
     4321 aacaacagta ccgccaacaa ttagtcggtc aattctaata ccgttatcta ctaaatgaag
     4381 gattgtttcc ggctctttca cgatgacaaa tactttttcc tgatcgtatt tccccttttt
     4441 aaaattcgca atcgctgttt cttcagtgat aattgataca gccattccag caggtctagc
     4501 taaacgcata cttgattttt ggatgtcgtt atttgcgaca gaatcatcga tcaccatcac
     4561 tctgtttgct ttagacattg gtgcccattg cgtgacaata atcccatgca ataaacggtt
     4621 atcaactctc gacataacaa tactcataaa tacttcctcc tttatctttc attttcttac
     4681 aagcaattac catgccaaaa caaaaagaac ttgataaatc aagctctttt tacataatca
     4741 taaacgtatt taacctcatg aatcgggatg tcgacactat aataatgttc aacgacactg
     4801 aaagattgct taaaatgtgt ctgaaatttt tgaaattcct cactcgtttc attgaaataa
     4861 atttcatctt ccaaagtatt ttgttttact aatcgttcaa ttaagcaact aatgtgaaca
     4921 tataatccga aacacgtatt attatcaaat gaaattccta gatc
//
LOCUS       DADVXB010000164         4918 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.170, whole genome shotgun sequence.
ACCESSION   DADVXB010000164 DADVXB010000000
VERSION     DADVXB010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.170"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..760
                     /locus_tag="KB902_002515"
     CDS             <1..760
                     /locus_tag="KB902_002515"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HBB6809286.1"
                     /translation="NIKYLFPTLMYILCMFISGNRVFLVKLFAIVFLIYIVMKSDVSP
                     RGRVPVMQVVRKTLFVAVAILAVFYALRGITKVNSTAATREFSDYITYYIGSPVYMLD
                     KYLQRYSPELNWGAKSLTSLVEMFGIEPEFKNAYIHVGGDSNFAGNEFSWFQRPYSDF
                     GWLGMLVFTFIVFWIFSWNIHIRINKEKNRRRRKYYILITAYFFYIPVMSFYYCQMCF
                     AFSITNIFSVVVACLLVREFTKRQDEIIFKIKEE"
     gene            762..2189
                     /locus_tag="KB902_002516"
     CDS             762..2189
                     /locus_tag="KB902_002516"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024832.1,HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HBB6809287.1"
                     /translation="MNRLIKNYAYNLCYQILVMILPIITTPYVSRVLKAEGVGEFNYS
                     YAIVSVAVIIAQLGTNMYGQREIAYVQNDKIRRSGVFWSIFVIRIISSFIVFPVYILI
                     SATLHSYTVLLISMSVYLVANLFDVSWFFQGMEDFKKTAIRSMVVKLIGLVLIFLLVK
                     NENDVVLYSVILAGTELLGNALLCCHIPKYVRRISIHDISITPHIRPILGLFLPTAAV
                     YIYTYVNKIILGIFSTDVQVGLYSQPEKIVKLLMTVITSLGAVMLPHIAVAVKENNID
                     RIRKEVLNAVSFVFCIGAPMVVGAIIIANTFIPWFLGDGYAKSVSLFQLLSPLILIIG
                     FASVVGQAVLIPMKRQRVYTFSIMTGAVINLVVNLALIPHLEAIGAAIGTIFAELTVT
                     AIQFYEVRNCIELKMASIITNVKNYLIGALIMGGVGGYVSSKLPNSVISTFITVILCI
                     LLYSILLICMKDKLLMDYLKRRKNR"
     gene            2186..2923
                     /gene="kdsB"
                     /locus_tag="KB902_002517"
     CDS             2186..2923
                     /gene="kdsB"
                     /locus_tag="KB902_002517"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: protein motif:HMM:NF003952.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HBB6809288.1"
                     /translation="MKTIAIIPSRYGSSRFPGKPLAMISSKPMIQWVYENVSKAAMLD
                     AVYVATDDKRIFDCVESFGGMALMTSDKHTCGTDRLAECAEILQLRDEDLVLNIQGDE
                     PLIKAEMIADLYSCFDNDEVYMGTLKKHIEVQEELDNPNVVKVINDVNDYAIYFSRFC
                     VPYERDGKNSLHFKHIGVYGYKTWFLKKYSTMPKTPLEVSESLEQLRVLESGFKIRVK
                     ETKYQTVGVDTPEQIQQVEDELRKEGL"
     gene            2925..3701
                     /gene="kdsA"
                     /locus_tag="KB902_002518"
     CDS             2925..3701
                     /gene="kdsA"
                     /locus_tag="KB902_002518"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010388312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HBB6809289.1"
                     /translation="MNRLMLIAGPCVIESEENVMLIAKTIKEITEKLDIDYYFKASFD
                     KANRTSITSYRGPGIEEGLKILKKVKETYGLKICTDIHEPWQAEKAAEVCDILQIPAF
                     LCRQTDLLVAAAKTGKIINVKKAQFLAPWDMKNVINKLVEAGNSNIMLCERGTSFGYN
                     TLVVDMTSIVEMKKFGYPVVMDATHSVQKPGGKGDVTGGNRNNVEPLAKAAVATGADA
                     LFFEVHPDPDNALSDGPNMVLLDEFEGLLERVLKVYNAVR"
     gene            3810..4775
                     /locus_tag="KB902_002519"
     CDS             3810..4775
                     /locus_tag="KB902_002519"
                     /inference="COORDINATES: protein motif:HMM:TIGR00393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HBB6809290.1"
                     /translation="MDKIIEAKRVFDIEIEALKRTRDCLGKTFVRILDAIVNCEGKVI
                     ITGMGKPGHIAAKLAATFASLGTPAFRLHPAEAMHGDLGMVSEKDIVIAISYSGESDE
                     IVKILPNIKMIGATLIGITGNSKSTLATASDIVQILPEFEEACYLGLAPTSSATSVLC
                     YGDALAVVASGIYGFKDSDFGKFHPAGSLGKKLILKVSDLMSHGNEIPMVNSGTLLMD
                     AISVMSNKGLGIVSVIDQDGTLKGIITDGDLRRIIERKVDIYSVEIDDVMIANPKVFT
                     KDKLAVDALRFLKANSINILPIIDDEGMLVGTITWQQIVKAGIVA"
BASE COUNT         1532 a          690 c         1065 g         1631 t
ORIGIN      
        1 aaatataaaa tacttgtttc caacattaat gtatatttta tgtatgttta tatccggtaa
       61 ccgtgtgttt ttagttaagc tttttgctat agtatttttg atatacatag taatgaagtc
      121 agatgtatcg cctcgtggac gagttcctgt tatgcaagtt gtgcgaaaaa ctttattcgt
      181 tgcagtagcg attttggctg tattttatgc attaagaggt attacaaaag ttaactcgac
      241 tgcggcaaca agagagtttt cagactatat tacttattat atcggaagcc cagtatatat
      301 gctggataaa tatctccaga gatattctcc agaattgaat tggggggcaa aaagtcttac
      361 ctcattggta gagatgtttg gtatagaacc agaatttaaa aacgcatata tccatgttgg
      421 tggagatagt aactttgcgg ggaatgaatt ttcgtggttt caacgacctt actctgattt
      481 tggttggtta ggtatgctgg tgtttacttt tattgttttt tggatttttt cttggaatat
      541 tcatattcgc attaataagg aaaaaaacag aagaagaagg aaatactata tactaattac
      601 ggcatacttc ttttacatac cagtgatgag tttctactat tgccagatgt gtttcgcgtt
      661 ttctataaca aatatatttt ctgttgtggt tgcttgcctt ttagtacgag aatttacgaa
      721 aaggcaggat gaaattatat ttaagataaa ggaggagtaa tatgaatagg ttgatcaaaa
      781 attatgccta taatctttgt taccaaattt tggttatgat actgcctatt attacgactc
      841 catacgtatc tagagtattg aaagcggagg gagttgggga gtttaattat tcgtacgcca
      901 ttgtatcggt agcggtaata attgctcaat taggtacgaa catgtatgga caacgtgaga
      961 ttgcttatgt tcagaatgat aagatcagaa gaagtggagt gttttggagc atctttgtta
     1021 tccgtattat ttcttcgttt atcgtttttc ctgtatatat tcttatttcg gctactcttc
     1081 attcatacac tgttttacta ataagtatgt ctgtttattt agttgcaaat ctttttgatg
     1141 tcagttggtt tttccaaggg atggaagatt tcaaaaaaac tgcaatcaga agtatggtgg
     1201 ttaagttaat tggtcttgtt ttgatattct tattggtgaa aaatgaaaat gatgtagtat
     1261 tgtactcagt tatattggct ggaactgagc tgttggggaa tgcattatta tgttgtcata
     1321 ttccaaaata tgttagaaga ataagtattc atgatatatc gataacaccc catattcgac
     1381 caatattagg attatttctt ccaacagcgg cagtatatat ctatacgtat gttaataaga
     1441 ttatattagg aatattttct acggatgtcc aagttgggct atactcgcag cctgaaaaaa
     1501 tagtgaagct gttgatgaca gtcattacat ctcttggtgc agttatgttg ccacatatcg
     1561 cagtagcggt taaagaaaac aatattgata gaattagaaa agaagtattg aatgcagtat
     1621 catttgtgtt ttgcataggc gccccaatgg tagttggtgc gattataatc gcaaatactt
     1681 ttataccgtg gtttcttgga gacggatacg ctaagtcagt ttccttattt cagttactat
     1741 caccattgat tttgataatt ggatttgcta gtgtggttgg tcaagctgtt ttgattccca
     1801 tgaaaagaca aagggtgtat accttctcta ttatgacggg cgctgtgatt aatctcgttg
     1861 tcaatttggc tttaatacca catttggaag ctataggcgc tgcaataggt acaatatttg
     1921 ctgaacttac agttactgca attcagtttt atgaagtaag aaactgtata gaattaaaaa
     1981 tggcatcaat tattacgaat gtaaaaaact atttgatagg tgcactgatt atgggaggcg
     2041 tcggaggata tgtcagtagt aagctcccaa attcagtaat atcaacgttc attacagtaa
     2101 ttttgtgtat tttactatat agtattttac taatatgtat gaaagataag ttgttaatgg
     2161 attatcttaa aaggagaaag aaccgatgaa gacaatagct attattccat ctcgatatgg
     2221 atcaagtagg tttccaggga agccgcttgc tatgatttct agtaaaccca tgattcagtg
     2281 ggtttatgaa aatgtttcta aggcagctat gctagatgca gtatatgttg caacagacga
     2341 taagagaatt tttgactgtg ttgaaagctt tggtggaatg gctttgatga cttctgataa
     2401 acatacttgc ggcacagatc gtcttgctga gtgcgcagag atccttcaac tccgggatga
     2461 agacttagtt cttaatatcc aaggagacga gccccttatc aaggcagaga tgatagcaga
     2521 tttgtattct tgctttgata acgatgaagt ttatatggga accttgaaaa aacatattga
     2581 agttcaggag gaacttgaca atccaaatgt tgttaaagta atcaatgacg tcaatgatta
     2641 tgcgatatat ttttcacgtt tttgtgttcc atacgaaaga gatggaaaaa attctctgca
     2701 ttttaaacat attggtgttt atgggtataa aacatggttt ttgaagaaat acagtacaat
     2761 gcccaaaacg cctcttgaag tatctgaatc tctcgaacaa cttcgagttt tggagagtgg
     2821 atttaagatt cgagtaaagg aaactaaata tcaaaccgtg ggggtggata cgccggagca
     2881 gatacagcag gtagaagatg aattaagaaa ggaaggtcta taagatgaat agacttatgt
     2941 taattgcagg accatgcgtt attgagtccg aagaaaatgt aatgttaata gctaagacta
     3001 ttaaggagat tacggagaag ctcgatattg attattattt taaggcttct ttcgacaaag
     3061 ctaacagaac tagtattacc tcttacagag gtcctggtat tgaagagggt ttgaaaatcc
     3121 ttaagaaagt taaggaaact tatggattga aaatttgtac agatatccat gaaccttggc
     3181 aagcagaaaa ggctgcagag gtatgcgata tacttcagat tcctgcattc ctgtgtagac
     3241 agactgattt actagtggca gcagcaaaaa caggcaaaat aattaacgta aaaaaagcac
     3301 agtttctcgc accgtgggat atgaaaaatg ttattaataa acttgtggag gcaggtaata
     3361 gtaacattat gctttgcgaa cgtggcactt cttttggata taatacattg gttgttgaca
     3421 tgacatctat tgttgagatg aagaagtttg gttaccctgt tgttatggat gctacgcata
     3481 gtgttcagaa gcctggtgga aaaggagatg ttacaggagg taatagaaat aacgttgagc
     3541 ctcttgcgaa ggcggctgtt gcaacaggcg cagatgcttt gttctttgaa gtacatcctg
     3601 atcctgacaa tgccttgtct gatggtccga atatggttct cttggatgaa tttgaggggt
     3661 tattagagcg tgtactaaaa gtatacaatg ccgttagata atttttcttg cattgcatag
     3721 aaatgtatgg taagtctttc acattttgta ctgtgttaca acatgtgaaa gacctccagc
     3781 tgctattaaa aactgaagag gtaaataaaa tggataagat aatagaggcc aaaagagttt
     3841 ttgatattga aattgaggcc ttaaaaagaa cgagagattg tcttgggaag actttcgttc
     3901 gtattcttga tgcaattgtt aattgcgaag gaaaagtcat tatcactggt atgggaaagc
     3961 caggtcatat cgctgctaag ctggcagcga catttgcaag cttaggaaca ccagcattca
     4021 gacttcatcc tgctgaagcg atgcatggag atttaggtat ggtttcagaa aaggatattg
     4081 taattgctat cagctatagc ggcgaatccg atgaaattgt taaaattctt cctaatatta
     4141 aaatgattgg ggctacttta attggaataa caggcaattc aaaatctacg cttgctaccg
     4201 catctgatat tgtccagata ttaccggagt ttgaggaagc ttgctatttg ggattggctc
     4261 caacttctag tgctacaagt gtgttgtgtt acggcgatgc attagctgtt gttgctagcg
     4321 gtatttatgg atttaaagat tctgattttg gaaagtttca tcccgcaggt tcattgggca
     4381 aaaaattaat acttaaagtg tctgatctaa tgtcccacgg caatgagatt ccaatggtca
     4441 attcgggaac attgttaatg gatgctattt ctgttatgtc gaataaaggg ttgggtatag
     4501 tttcagtcat tgatcaggat ggaactctca aaggcattat tactgatgga gatttaagac
     4561 gaattattga gagaaaagta gatatctatt ctgtagaaat tgatgatgtg atgattgcta
     4621 atcccaaagt atttactaaa gataaattag ctgtcgatgc attgagattt ttaaaggcta
     4681 atagtattaa cattcttcct ataatcgatg atgaaggtat gcttgttggt accattacat
     4741 ggcagcaaat tgtaaaagct ggtattgttg cataaaggag ataaatgaaa aagttaagtc
     4801 taaaaaaatg gaaattgaat ttccagaagt ctatattttc ttataaaaaa ttccttgttg
     4861 gaattagaag aaggtcgata tgatctttcc aatggaattt atctgaatgt tgagtcct
//
LOCUS       DADVXB010000165         4881 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.171, whole genome shotgun sequence.
ACCESSION   DADVXB010000165 DADVXB010000000
VERSION     DADVXB010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.171"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(25..714)
                     /locus_tag="KB902_002520"
     CDS             complement(25..714)
                     /locus_tag="KB902_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6809291.1"
                     /translation="MESEDLLSRISKVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYAAYRIRKEEPGSPIFFSHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTQIGKIIRAKSIDELPQLWNVLKGDMSLVGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSGRNDVSFHAMVDLDLEYITNQSLLNDFKLIIKT
                     IWIVIKPNGAY"
     gene            complement(768..1532)
                     /locus_tag="KB902_002521"
     CDS             complement(768..1532)
                     /locus_tag="KB902_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBB6809292.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIVMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIQRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(1560..2258)
                     /locus_tag="KB902_002522"
     CDS             complement(1560..2258)
                     /locus_tag="KB902_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBB6809293.1"
                     /translation="MARTQKQKATPTHAVSLITLTNPSSPIAEQYRTIRTNIQFASTT
                     GQQIKTIVVTSSGPGEGKSTTASNIAVVFAKSGQRVLLVDADLRKPVIYKTFQLNNAS
                     GLSTALSSSGSVADVIQRAPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPIVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDDGYYYGN"
     gene            complement(2271..3050)
                     /locus_tag="KB902_002523"
     CDS             complement(2271..3050)
                     /locus_tag="KB902_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBB6809294.1"
                     /translation="MEETISLEEIFETLRKHLITIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVQERLKTEDNVKMTP
                     EQIKDAISINQSENSQMFSIQAISTSAMTAQQIANTTSQVFQENAKDVMNVDKISIVS
                     GAVANTTPISPNNKLNLVIGLMLGMMVGVVLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSEKELKAGIRKKGLAPTRPKVTNDKTASSRRSRSRV"
     gene            complement(3066..4010)
                     /locus_tag="KB902_002524"
     CDS             complement(3066..4010)
                     /locus_tag="KB902_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6809295.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLNKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGVQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSILNALESNMKTDMSFDEMKKIALDYREAFDTIKQD
                     QMQGEGFMQDDISYQKVNDNELDRVKKELKEQMNLENK"
     gene            complement(4047..4823)
                     /locus_tag="KB902_002525"
     CDS             complement(4047..4823)
                     /locus_tag="KB902_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809296.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKIRAAYATKAQTVAQQMGYSNIS"
BASE COUNT         1258 a         1045 c          856 g         1722 t
ORIGIN      
        1 acaatctatc aattctatcc cttactaata tgccccattt ggttttataa cgatccaaat
       61 tgtcttgata attagtttaa aatcattcaa tagactttga ttagttatat attctaaatc
      121 taaatcaacc attgcatgaa aactaacatc atttctacca ctaacttgcc acaaacctga
      181 acatccaggt tttacataca agcgttgaag atcatatctc gtgtactcag ctacttccct
      241 ttccaaaggt ggacgtgggc caactagact catatctcct tttaaaacat tccatagctg
      301 tggcaattca tcaatgcttt tagcgcggat aattttacct atttgggtga cacggggatc
      361 ttctttcatc ttgaacattg cgccttctat ttcattttga tcaagtaact cttccaattt
      421 ttcttcagca tctaaacaca tcgaacggaa tttatacatt ttgaatgttt ttccattttt
      481 accaacacgt gtatggctaa aaaatatcgg actccctggc tcttcttttc tgattcgata
      541 agctgcatag aacatcaaag gagaagctaa aatcaaacca atgatgcttc ctacaatatc
      601 aatcattctt ttaaaaaata aatagatata tcgtttttca actttttctt tatccaacca
      661 aacttgatta ggatgtactt tactaatacg agataataaa tcttcacttt ccatactttc
      721 agtccctttc gctctctatt catttccttt ttatctacga ataaaaacta aaataaacca
      781 aacttcttct tttttacctc ttcatatatt ggataactga tctcatcccc gttgatcaga
      841 tcctttgcga cttgcttcat ctgtactact ttttccttac caaagtcctt ggcaatctgc
      901 tcatagcact cttttaagta aaaggtgcgc ttagagaccc catgggcatc agaagcagcc
      961 atctgcacga gattatgttt gaccatcgtt ttggctgttt tctggatatc tttgccaaat
     1021 accccaacat aacttggcgc agtgagttgc gccaaacatc ccatatctag gaacggaagc
     1081 aaatgattcg ggtcttcgcg aaaatgcgcg ttacgttctg gatggacgat cactggtgtc
     1141 tttcctagtt ctaacaactc aaaaaaaagc tgctctgcat ataacggcac ttccagtgtc
     1201 ggaaattcga tcagaagata tgtatcatct aaatctgtaa ataaaatttc atctcgctgg
     1261 atgtcttcaa tgagcgttcc ggtaatacgt acttcttgtc cttccaataa cgtcaaaggc
     1321 aattgtcttt tctctaattc tgcttgtaac gaagcgacta gagaaatgac ttgtgatttt
     1381 tcattgctgt attttccatt attgtggtgt ggcgtgcata aaatatgcgt gatgccttgc
     1441 tgaatcgctt tttcagccat tacgatactt gcctctaggt tttccgcccc atcatcgatt
     1501 cctggtagga tatggcaatg tagatcgatc atttctcttg cctcctctct tcttatttct
     1561 taatttccgt agtaataacc atcgtctttg ctgtgttctg ctccgttgta tacaacacct
     1621 aggactcgtg cttgtaccat ctccaacagc tcttttgctt tagtcaagga ttctttacgt
     1681 gacgtatttt cacgtaccac caataaggtg ccatccgttt ttgaagacat gatctgtgca
     1741 tctgttacgg ctactattgg tggcatatca aaaattacca cgtcaaataa ctgtcttgct
     1801 tctgctagga tctgatccat tcttggcgaa cttaacaatt ctgatggatt gggtggctta
     1861 ggtccactag gcaaaatcga caagttctcg actggcgctc gttggatcac atctgctaca
     1921 cttcctgatg aactaagtgc tgtacttaat ccactggcat tgttcagctg aaatgtctta
     1981 tagatgacgg gtttacgtaa atctgcatcg actagtagaa ctcgttgacc agatttagca
     2041 aaaacgactg caatgtttga tgcagtggta gattttcctt ctccaggacc tgatgatgtc
     2101 acgacaatcg ttttgatttg ctgaccagtt gtggaggcaa attggatatt cgtccggatc
     2161 gtacgatatt gttcggcgat tggtgaagat gggtttgtta acgtgatcaa actgactgca
     2221 tgagttggtg ttgctttttg tttctgtgtt cgtgccattt ttcttccctc ctaaactctt
     2281 gagcgacttc tgcgtgatga ggctgtttta tcgtttgtaa cttttggtcg tgtaggagcc
     2341 agtccttttt tacggatacc agctttcaat tctttctctg acatttctgg aactgttcct
     2401 aagattggga accctaatgt atccgtcaca tatttttcat ctttcactgt tcgatcgagt
     2461 aattcaaata agaatgccag aactacacct accatcattc ctaacattaa gccaatcact
     2521 agattcaatt tattatttgg cgaaataggt gtcgtattgg caactgcacc tgaaacgatc
     2581 gagattttat caacattcat cacgtctttt gcattctctt ggaaaacttg tgaagttgtg
     2641 ttagcgatct gttgagcagt cattgcactc gtgcttattg cttgaatcga gaacatttgt
     2701 gaattttctg attgattgat tgagatggca tccttgattt gttcaggagt cattttcacg
     2761 ttgtcttctg ttttcaaacg ttcttggact tcatttagca ctagatcact gacgatcata
     2821 tctttatacg tattgatcat ttgcaagttc gtattgacat cattgacatt tgcagtatct
     2881 gattgcggca gtgtcacaat caactgtgct tgcgaactgt attttggcgt caaaatgaaa
     2941 aacgttacaa ttcctgagat agccaagcca gcaaacatcg agatgatgat tgttatcaag
     3001 tgtttgcgta atgtttcaaa aatttcttcc aagctgattg tctcttccat tttttctcca
     3061 ctttcctatt tattctctaa attcatttgt tcttttaatt cttttttcac acgatcaagt
     3121 tcattgtcat taactttttg atatgagatg tcatcttgca tgaagccttc tccttgcatc
     3181 tgatcttgct tgatcgtatc aaatgcttcc cgataatcta aagcaatctt tttcatttca
     3241 tcaaagctca tgtctgtttt catattcgac tctagagcat tcaaaatgga ttgatagttg
     3301 ctgacaccat ttagactcaa tacttttttt gctacgcctt ctacgatctt tctttggcgc
     3361 ccttgtctac cgtaatcacc atttgggtct tcataacgca tacgagaata agataatgcc
     3421 tgaaccccgt tcaatgtaat tttaccgatt ggaaagtcat agccatcttg tgagaaagtg
     3481 aggtcattat tgacttcgat accaccaact gcatcaacga gttcctttag ccctttcata
     3541 ttgatagaga catagtgatc gattgggatg tctacatatt tttgtacggt atccatcgcc
     3601 atggcagctc cgccgaatgc gtaagcgtgg ttgatcttgt cttttgtgtc acgacctacg
     3661 atgtcgacat acgtatctcg aggaatgctg acgatcgttg tctgtttgtc ttcaggactg
     3721 actgtggcaa ccatcatcgt atctgatctt ccttgatcga cccgacctaa atctccagta
     3781 tcaatcccca tcaatagaac agagaaagat tcttgtttgt tcagatcaac tggtttcgtt
     3841 cgttctcctt gggttcgttc cactgactcg taagttttct caatagaatg tgagagatcc
     3901 agatataatt ttgctcctac tcctacaatt gctaatacta atacgataag aactgctaaa
     3961 ataatcagaa atattttttt ccctcttgat tttcttcttc gtcttgccat agtttcctcc
     4021 gtttgctagc tttgctttaa ttgttactaa cttatattgc tatagcccat ttgctgagca
     4081 acagtttgtg cttttgttgc gtatgctgcg cgtatttttt cattccggat ctgctctatt
     4141 tgactgagca ccgtcaaata ttgatcgtaa gtagcggtgg cagtcacttg accatccttc
     4201 aacatcgtat cgaataactg atctagttgc gtgacttgcg cgatctgagt atcagcgaat
     4261 cctagatatt gcataacaac cgttttccaa ggactatctt taaaaaagct catattttca
     4321 cgtacacgag cgacatctgc acttgtcacc ttttctttga tgacgacatc gtctacagct
     4381 tgctgccagt ttgatacatt tttagtaaat aaatcgttga cagctgtctg gatcttcagt
     4441 tttgattctg catcctctaa ctgcgttaag actgctttct tttcttcttg gatcgcagca
     4501 gcttctttag gtaattctga ttccttgatg tcataatcat ctgccgaaag tttgatagaa
     4561 gatagtttat gtgacaaatt tgaaactgtt tcttctgtta tttcaggatt taggaaaatt
     4621 ttttcttttg tactgtacag cttatctact tcttttgata aagaggtcac ggtgtctttt
     4681 tgattggtga tggcagattc tgcgtaattg atccgttgat gatgttgccg ctgattattg
     4741 aaatggtatc caaacaagca aatcacaata gcgcctgtgc ctaccgccac agtagccaat
     4801 aacttgacga acggcttttc catagattca ctcctaaata ttgatgatag ataaataaag
     4861 atgtgattca ttcccatcag a
//
LOCUS       DADVXB010000166         4798 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.172, whole genome shotgun sequence.
ACCESSION   DADVXB010000166 DADVXB010000000
VERSION     DADVXB010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.172"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(131..1939)
                     /gene="pepF"
                     /locus_tag="KB902_002526"
     CDS             complement(131..1939)
                     /gene="pepF"
                     /locus_tag="KB902_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBB6809297.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2115..3113)
                     /locus_tag="KB902_002527"
     CDS             complement(2115..3113)
                     /locus_tag="KB902_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBB6809298.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3339..3992)
                     /locus_tag="KB902_002528"
     CDS             complement(3339..3992)
                     /locus_tag="KB902_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBB6809299.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4324..4722)
                     /gene="spxA"
                     /locus_tag="KB902_002529"
     CDS             complement(4324..4722)
                     /gene="spxA"
                     /locus_tag="KB902_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6809300.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1413 a         1008 c          752 g         1625 t
ORIGIN      
        1 acaaaaaaga tgttggtgaa gttcaccaac atcaaaaagt atagagcctt aaaaaaatac
       61 gtcgactccc ttacaagaga gccgacgtat ttttttcgtt tctattcgag aaaatcaaaa
      121 atagaaagcc ttataaacga tcgatcaatt cttctaattc atttagacgt tgttcaaaca
      181 tcgacattgc atcttcaata tatgcagcct gtgtcatatc aactcctgct tttttcatta
      241 cttccacagg ataatcgctg ttacctgctt ttaggtaagc caagtagttc tctagtgcct
      301 ctggttcctg gtttagtatt ttcttcgcca gtgctgaagc agcagaaaag ccagtcgagt
      361 attggaaaac atagtaatta taataaaaat gcggtatccg tgaccattcg aatttaattt
      421 ctgggtcttc ttcgactgct ggaccataat attttgcatt caatttacca taactatcac
      481 ttaggtattc actagtcaat ggcacacctt tttcatcttc cgtatgcatg aaatgctcga
      541 attcagcgaa ttgtgtctgg cggaaaactg ttcctttaaa cccatccaag taatggttga
      601 gtacataagc ccgtacacga gggtcttttt ctgtttccaa taaatactcc gttaggatat
      661 tttcattcgt tgtcgaagca atttctgcta aaaagatgga gtagtcgccg tacacataag
      721 gctggttcga acgagtgaaa taactatgaa cactatgtcc catttcgtgg acaagcgtaa
      781 atagctgatc cagcgtatca tgccaattca ataaaatata tggatttgtg tcatagcttc
      841 ccgaagaata agcaccgctt cgtttccctt tattttcgac aacatcgatc caacgttcag
      901 agaatgcttt ttctacgatg gccatgtatt cttcacccat tggtttcagt gcttctaaag
      961 ctttttcttt tgcttcttcg tacgtaaagg taattggagc ttcccctaag accggtgtat
     1021 aaagatcata catgtgcagt ttttccactt ctaataaacg tttccgtaat tccatgtatc
     1081 gatgtaacaa aggcaaatgc ttgtttacca cgtctaccaa agtatcgtat acactttcag
     1141 gaatatgatt attgctcaaa gacgcttctc tggcagagct gtaattacgg actttcgctt
     1201 taaaattatg tccttttata tgtgtgccta aagtagaagc aaatgtattt ctaaattgtt
     1261 cgtaaacact gtacaacccc ttaaatgctg cttcgcgcac ccttcgatcc gtgctttcta
     1321 gcaactgacc atacacgcca tgagataatt ggactatttc accattttct ccttcaatcg
     1381 ttggaaaaac tagatctgca ttattcaaaa cagcaaatgt atcacttgaa gcatcaaaga
     1441 tttcacctgc tccagcaaga agagattcct gctcagcaga taagacatgg gctcgattat
     1501 ctactatttg ctggatataa tggcgataga cttccaattt tggttcttct ttgaaatatt
     1561 gccaaatctg gtcatctgac aattgcaata tttctggttc aaaccaggaa acggcttcac
     1621 taactttcga aaacagactg cttgctcttg cataaagcgc ttggtaatct gtatttccag
     1681 tgtcttgatc gtttttaagg tgcgcatata cataaatgac ttcagtttgg cgataaaccc
     1741 tcaatacgaa ttcaatcgca tttaaaaatt gagaagcgcc ttgatcaagt gttcctttgt
     1801 gtttttcaga ttgttttaac tcttctgata attccaaata tttctcatca aactcttggt
     1861 cgcttgaaaa gatcttggtc aagtcccaag ttaaattttc aggcaattct tctcgttttg
     1921 gcaactgctt tacttccatg aaatccactc cttttcttcc cttagctcta tctatcaaaa
     1981 tagatcatag tctaacatcc acatgtcaca gcatctaact tttctactca ttcatgtgtc
     2041 tgcttccatc aattttagca taactaaatc ttgttttaca tagaaaaccg attcctagcc
     2101 tatttttata cttactattt tttcaaagaa gacaagtgta tgcattcgtt aaaaaactgc
     2161 tgatagacca tctcttcatc aatcatagga aaaagccatt cccttttatg ttcttttatt
     2221 tggcaaagcc atgagttgaa atcaggaact ttctggtttt ccaaggcttc ttcgtacaac
     2281 attcgataaa gaaaaacctg ttcttgtaaa taaaagaaaa accgactttt ttgatagatc
     2341 cacgatgata gatgcaaaag atgtttatga cgcaagtagc attgttcttg tatggatact
     2401 gtattctttt gcttgtgaat aagttggcgt gtcagccatt tcttcccatc ttcactcact
     2461 ttttctattt ttttcatttg gttcatttta atttcgttac tagtgaatat ttctttaagg
     2521 tccctactag aaaaagtcca gcagctactg caaaaggaaa tatgccctga tacagtctct
     2581 gtaatatgat gatacaaata aagcttttgt ttcttgagat cagctttcca gcaatgcact
     2641 cctctttttc tattatagta gcagcaactt ttttctatca atgagaattg cgattgtcca
     2701 agaaaagaat taccaagtat ccaccatact tggtaactgt tattcaaata attttgggtt
     2761 ctttcaataa atctctggtg agacagtcta gaacattgga tttctattgc tagattcgcc
     2821 aacaaaatat ccggcctttg ccgcaacctc ggcaaatagg cttccaaaaa tactggttct
     2881 actgactgtc ccagccaatc catgaagcat tcctttaact gtaagtgctc ttttgattct
     2941 ctttcactaa agaccgaaca gttatctgat ttttgatggg caaaatgagc acattttttc
     3001 tttccctttt tcaaaatcac tctttttcga cagccacgac aataatattt ctttcctttt
     3061 tctgcatgtt tagcaaaaca gcacttatta tattcattca ttgcaagcag catttttctc
     3121 cctctgaact tatttacgtc taagaattta tttacacgaa aaaagagggc gtgaaaaagc
     3181 tattctgcat caagtaataa gaacagctaa acaaaaatag ttcccaatat ttttcgtttg
     3241 gttgggcttg ttaccgcaga tgcaagcttt tgaacacatt tatacgaaaa aaagactgcg
     3301 acacaatttt tgtcacagtc tcttactata atgctgattt atacaaaata aaatttcgtt
     3361 cgctcgatag cattacgcgc catcagacat tgtccatatt cattcaatgt ttctggtgta
     3421 cgatcgctct tttcagcaaa ctccaaaatt cgagcaatct gattctctac atccgcttgg
     3481 ttgagatttt ccatccagaa gtgaacgact aggtaatagc gctcttcgaa taaatacaaa
     3541 tcagtccaag cagactctag ttcgacatct gttgcaagtt ggatcacttg ttcaaaatct
     3601 tcaaaagcaa aagttgcttg tctttcctgt tcttctaggg cgcttccaga taattcttcc
     3661 tccggatcgc tgccaataat ctgctgacga agaaagtcac tcacatcttc tgaatcaaca
     3721 gtagaatctt ctgattgaga aatttcttca tccggaagat ttttactgat aaacagttct
     3781 aatccgtctc cttttggcaa aacttggaaa gtgacagctt cgcttcctcg gaactcctct
     3841 tcgatatcaa cttcttccaa aatactataa aagaaatttt cgatttcttt gtgattgcca
     3901 agtaaatcca aaaatgaaac gccccgttcc tctaaatctt catgaccaat tagtacacgg
     3961 atcgtatttt cattaatatg ttccatttcc attttgctac acctcacttt gccacaatgt
     4021 ttaatataga ttcattgtag cgaaatcagc ttaaatgtaa agaaaaaaaa tctcgctgtt
     4081 aagcgaattt aataaaacca gcggattttt caacctttca agctatctta tttaactata
     4141 acatttttgg cagacgaata ctatatagcc gacttttcag ctaattttcc ctctctattt
     4201 ttcgtgcaat catcatcttc tactaccttt ttatacatct aatcaagaat actttttgta
     4261 aaaacaaaaa aacttggaaa aactatcttt gtaatagtct tttccaagtt tcgtattatc
     4321 cttctataat ccagccatca attgtgcttg acgtaattct aattgtcgta catcgcgcgg
     4381 taggaaccga cgaatttcat cttcattaaa accaacttgc agacgtttat catcaatcat
     4441 gattggacgg cgaagcaatc caggattgtt ttgcacaagt tccaataatt cttgtaacgg
     4501 cagatcatct aaatccatgt tcagtttttg gaatactttg gaacgtgtcg agatgatttc
     4561 ttctgttccg tcttctgtca tttgtaaaat cgcttttaat tcagaactgt tcaatggttc
     4621 tgaaaaaata ttacgttcaa caaatggaat ctgatgttct tgcaaccacg cacgagcctt
     4681 tctgcaggaa gtacaacttg gggaagtata taatgttaac aacgtgcacc actccttttc
     4741 gtgataagaa tcactttttt gtaacagaag atcataataa tctcccatct gtttctat
//
LOCUS       DADVXB010000167         4600 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.173, whole genome shotgun sequence.
ACCESSION   DADVXB010000167 DADVXB010000000
VERSION     DADVXB010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.173"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(52..522)
                     /locus_tag="KB902_002530"
     CDS             complement(52..522)
                     /locus_tag="KB902_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBB6809301.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="KB902_002531"
     CDS             complement(681..1139)
                     /locus_tag="KB902_002531"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBB6809302.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="KB902_002532"
     CDS             complement(1310..2455)
                     /locus_tag="KB902_002532"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBB6809303.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="KB902_002533"
     CDS             complement(2468..3385)
                     /locus_tag="KB902_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBB6809304.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="KB902_002534"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="KB902_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBB6809305.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1439 a          840 c          871 g         1450 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
//
LOCUS       DADVXB010000168         4467 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.174, whole genome shotgun sequence.
ACCESSION   DADVXB010000168 DADVXB010000000
VERSION     DADVXB010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.174"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..238
                     /locus_tag="KB902_002535"
     CDS             <1..238
                     /locus_tag="KB902_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6809306.1"
                     /translation="PRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
     gene            270..992
                     /locus_tag="KB902_002536"
     CDS             270..992
                     /locus_tag="KB902_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6809307.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            1050..3089
                     /locus_tag="KB902_002537"
     CDS             1050..3089
                     /locus_tag="KB902_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBB6809308.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(3198..4349)
                     /locus_tag="KB902_002538"
     CDS             complement(3198..4349)
                     /locus_tag="KB902_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBB6809309.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
BASE COUNT         1627 a          822 c          864 g         1154 t
ORIGIN      
        1 gccacgtaaa aacatggata aatcagaaaa actagaccac agcttacttg gaaaacaaag
       61 aaaaacagtt gagactgttt tttcttcctt agaaaaatta ggttgtcaaa atttcaactc
      121 acgttctgtt aaagggctag agagtagatt tgaaagcata ttactggctt acagtgttct
      181 attaagtcga gcacaacgac gttttgaagg aactttgaga tattctttag gatattaaaa
      241 ttaactagca ccacgggtta ttatctattt tgttactgct tacattagta gttggctatt
      301 tttcgattga gtttatccat ggattttcgt ctgcaaaaca gagttcaact gtgaaaaagg
      361 tagagccgaa aagtatccct accacactaa atgtggcttt gattggttca gatgctcgtt
      421 cgaaagacga aaacggtcgc tcggattcac ttctggttgc acaatacaac cagaaaacac
      481 aacaagcaaa actgatctct atcatgagag attcatatgt cgatattcca ggttacggaa
      541 tgaataagat aaatgcagct tactcttatg ggggagttga tttattaaat caaacattaa
      601 aggaaaattt caaatttgaa gctccctatt atgcaagtat cacatttcaa gattttatcg
      661 attgcgttaa tgaactgttt cctggtggag tcaagatcga tgcagaaaaa tctctagatt
      721 tagatggcgt atatataaac aaaggagagc aagtgatgga tggtaatact ttactccagt
      781 atgctcgatt tcgggaagac aaagaaggag acttcgggag gatcagaagg cagcagcaag
      841 tgatcaaagc tatctctcag cagctgaaag acgtaacttc aatattcaag ctacccaaag
      901 cggttgggaa attacttggt agtatccaaa cgaaccttcc agaaagtgtg cttctggatt
      961 gtggtatgga tttcctcaaa gacatatgtt agaataaaca ggtataaata gtgaaataaa
     1021 ggaatgacaa gcaagagaag gaggaaaaaa tgaaaagaag tgacaagcac ggcaaaaatc
     1081 gaacaggcgc ttatattgcc ggcgcagtga tcttaatagc agctgcgggt ggcggttatt
     1141 tttactacca gcactatcaa gaaacccaag cagtagaagc tggagaaaag acagttgagc
     1201 aatttgtcca agctttgaac aagggagatt ataacaaagc tgcagaaatg acatcaaaaa
     1261 aggcggcaaa taaaagtgca ttatctgaaa aagagatctt agataaatac cagaatatat
     1321 acggtgctgc tgatgtcaaa ggacttcaga tatcgaatct aaaagtagat aaaaaagacg
     1381 attctactta cagtttttca tataaagcaa agatgaatac ctcattaggt gaattgaaag
     1441 atctttctta taaaggaaca ttagacagaa atgatggtca aaccacgatc aactggcaac
     1501 ccaacttggt ttttccagaa atggaaggaa atgacaaagt aagcctgacc acacaagaag
     1561 cagcaagagg gaatattata gatcgaaatg gtgaaccatt agcaacaaca ggcaaactaa
     1621 aacaattagg agtcgttcca agtaaacttg gagatggagg cgaaaaaaca gccaatatca
     1681 aagcgattgc ttcctccttc gacttaacag aagatgctat caatcaggcg atttcacaaa
     1741 gctgggtaca acccgattac tttgtcccat tgaaaatcat tgatggagca acgccagaac
     1801 ttccagctgg agctaccatt caagaagtag acggcagata ttatcctttg ggtgaagcag
     1861 ctgctcagct gattggttac gtgggagata tcacagcaga agatattgat aagaatccag
     1921 aattaagcag taatggaaaa atcggtcgct caggtttgga gatggctttt gataaggatc
     1981 ttcgtgggac aacaggtggg aaattaagca ttacagatgc agacggtgta gagaaaaaag
     2041 ttctgatcga acatgaagtt caaaatggca aagatatcaa attgacaatc gatgcgaagg
     2101 cacaaaaaac agcttttgac agtctaggag gaaaagctgg atcaactgtt gcgacaacgc
     2161 caaaaaccgg tgatcttctt gcgcttgcta gctctccaag ctatgatcca aacaaaatga
     2221 caaacgggat ctcacaagaa gattacaaag cttatgaaga aaatcctgaa catccattca
     2281 tcagccgatt tgcgacaggt tatgctcctg gatctacgtt taaaataatt acagcagcaa
     2341 tcggtctcga caacggcact atcgatccaa atgaagtgtt gacgatcaac gggcttaaat
     2401 ggcaaaaaga cagttcttgg ggatcttttc aaacaacgcg tgtcagtagt gatgtatcac
     2461 aagtagactt aaaaactgct ttgatctatt ccgataatat atatgcggca caagaaacgt
     2521 tgaaaatggg tgagaaaaaa tttcgtacag gcttagataa attcattttt ggtgaagacc
     2581 ttgatttgcc aattagtatg aatccagcac aaatttctaa tgaagatagc tttaactcag
     2641 atatcttgct agctgatact ggatatggac agggcgaact tctaattaat cctatccagc
     2701 aagcagcaat gtattctgtt tttaccaaca atggcacact tgtctatcct aaattgattg
     2761 cagataaaga gacaaaagat aagaagaatg tcatcagcga aacagcagta caaacgatcg
     2821 tgccagatct gagagaagtt gtgcaagatg taaatggtac agcacattct ctttctgctt
     2881 tagggattcc gttggcagcg aaaactggta cagcggaaat caaagaaaaa caggatgtaa
     2941 aggggcaaga gaacagtttc ttgtttgctt tcaatcttga taaccaaggt tatatgatgg
     3001 tcagcatgtt ggaaaataaa gaagatgatg attcagcaac caaacgagca tcggaactat
     3061 tgcaatacct caaccaaaat tatcaataaa aaattgcttt ttaagtacag taaaaggact
     3121 gtggcgttat cgtcacagtc cttttttcaa ataaacggtt ttcacgatgt ctctttcaca
     3181 acttcttttt gatttactca cacttcataa actttttttg taaaatattt gagaacaagt
     3241 ggagaaataa gtgtacttaa taaaatcacg ataactaaag gtgaatagta ctgtggttcg
     3301 atcaattgac tttgctgtcc aatttgtaaa atgatcaaag ccatttctcc acgcgaaatc
     3361 ataccagcac cgaccatcaa tgaactatgt tgagaaaaac cggcaatctg agcaccaaaa
     3421 taacctccaa gcaatttggt caaaatcgct acaagcgtca atatagaaat aaagagtagt
     3481 tgttcactaa agtcagaaaa atcaacttct aatcctacac tgacaaaaaa tactggtata
     3541 aatactgcat atcctaaagc ctctacattg tggtatactt cttctttaac ctttgtctga
     3601 ctgacagcta tcccagcaaa aaaagcacca atgacagagc taagcccaac aagatccgct
     3661 acgtaagaca ttcctaaaca aataactagc gatacgatga taatagaaga atttgcgtac
     3721 actttttctg caaatgaaag taggaaaggc gcaatccatt tgactaataa gaaaataaaa
     3781 acaaaataaa ttagctgttc aatcaaaaca agcggtaaag aagcattgct agaagcttcc
     3841 cccgttagaa aagataggct gaaacttaga actaaaacga ctaaaatgtc atctaccaca
     3901 gaagcaccca aaattgttga tccttctttt gtattcacta cgtttagttc ttttaatact
     3961 tctactgaaa tactgacaga agttgccgca agaataatcc caaagaaaat cgcttcattt
     4021 cccgaaactt ggaatgcttt gcctgtcaac cagccaaaaa caaccgggaa gatgatccca
     4081 agcaaagcaa cgaacatacc aggtcggaaa tattttttca aaagagataa atcactttcc
     4141 agaccagcta aaaacattaa taagatcaca ccaatctccg aaaagtcatg gactagaata
     4201 tcaggtttga cccaattcaa tccagcttgg cctagcaaaa caccaacaag taattgtcca
     4261 atcactgctg ggatacctaa tctccgcgag atatgtgagc caatcgttgt tgaaatcaat
     4321 atcaggcata aaataccaat aaattccatt ctcatcattc ctttgtataa aatatagccc
     4381 gaacttagca taacatacat tattgaaaaa ataggaaaat atactcacaa aaaaaccaac
     4441 aatccaaaag atttttttgg attgttg
//
LOCUS       DADVXB010000169         4415 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.175, whole genome shotgun sequence.
ACCESSION   DADVXB010000169 DADVXB010000000
VERSION     DADVXB010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.175"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            58..912
                     /locus_tag="KB902_002539"
     CDS             58..912
                     /locus_tag="KB902_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6809310.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="KB902_002540"
     CDS             1009..3258
                     /locus_tag="KB902_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6809311.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4415
                     /locus_tag="KB902_002541"
     CDS             3261..>4415
                     /locus_tag="KB902_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6809312.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          805 g         1429 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DADVXB010000170         4383 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.176, whole genome shotgun sequence.
ACCESSION   DADVXB010000170 DADVXB010000000
VERSION     DADVXB010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.176"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            92..1393
                     /locus_tag="KB902_002542"
     CDS             92..1393
                     /locus_tag="KB902_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6809313.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1420..1680
                     /locus_tag="KB902_002543"
     CDS             1420..1680
                     /locus_tag="KB902_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6809314.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2679..3914)
                     /locus_tag="KB902_002544"
     CDS             complement(2679..3914)
                     /locus_tag="KB902_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBB6809315.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1284 a          696 c          895 g         1508 t
ORIGIN      
        1 taaaatttct taattatata attagttatg aacattcttt gcgtcgtcat gcaatgaatg
       61 gttcatattt tattgaaaag gagtggtttt agtggaaaag ctgatgaaat gggtcgaaga
      121 gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt catttattag caattcgtaa
      181 tggggttgtt tcaacattgt cattgatttt gattgggaca ttttttatgg tctttatcaa
      241 tttaccgttt cctggatgga atgaatttat tgccccttat tcggcaacga ttgttttacc
      301 ctttaggatg acgatgggat tgatggctat ttatgcaact tttgttatgg gttcggatct
      361 agctaaatca tatggattag atagtgtgac aggtggtata ttatctttag gaacgttctt
      421 tatgttacaa gttcctgtaa acgttttaac tcctgaagag gcacctcttg gctgggtctt
      481 acctatgagt tctttgggag catctgggat gtttgcgggg atcttatcta tgatttttgc
      541 agtggaagta tatcgtttct ttaaaaatcg aaatattact atcaaaatgc cagaacaagt
      601 gccacctgct gttgcccgta gttttgaggc attgattcca ggtgcagtca ttttaacaat
      661 tacttggctg attcgaagcg tcgcgggctt tgatgtaaac gctgccttat tatcgttatt
      721 cgagccttta accaatattt tagggaataa tttgcttggt gttttactac caatgttttt
      781 gatccatttg ttgtggtcat ttggtatcca tggcatgagt attgtagggg ctgttgttcg
      841 tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca ttggcagatg gtacagctgc
      901 cacccaatta ccctatatcg ctcctgaaca gttttatcaa tggacggtaa caattggtgg
      961 tgcaggagca acgatcgtgg tatctgtttt gtttatattc ttctgtaaat caaaattctt
     1021 gaaagaggtt ggtcgttttt ctattattcc tggtatcttc aatatcaatg agcccataat
     1081 ttttggagct cctatgatgt tgaatcctta catgttcatc ccgttcaact tagttccttt
     1141 agttttgact attatcagtt attttgcagt caaattagaa atggtcaata gatttactgt
     1201 tttgccaaca tggacattac cagctccaat cggcggttat ctttcagcag gaaatgactg
     1261 gcgtgttgtt atcttgatca tgatcaacac attgatagca tttattatct attatccatt
     1321 tgtaaaagct tatgataaaa agatgctgtc agatgaacaa agtcgtggag aaaacgaagt
     1381 ccagactgtc taagtttggt ttttagaagg tgggaaacaa tgtattggct gattttattt
     1441 tttgttttta tctttttatt aacggctagt caccttatat tgaatatgct agctacatat
     1501 catattcaaa tcaatcgatg gatttgggca ctggcatcat ttttgatcgt gattcttcca
     1561 aagatcattg taccgcatat gaatgttttg ttttcatggg ggacatatgt actttgtgga
     1621 atttttgcta tcaattttat gatcgagcag catagatggt ttgtcacatc gaagctttaa
     1681 atgttctaaa agtggttgta acagaagtgg ttagcttcaa gaaataagaa gaaatttacg
     1741 aaaattgctt cttaaatttt tgtgaaatgt tggcttattt ttcgtttggt tgaacttatt
     1801 accgcagatg caagcttttg accaccgttt attcggaata tgggactgtg acaaggcttt
     1861 tgtcacagcc cttttttaca taaagattat tattgtttta actgttttgg cagaaagaag
     1921 gaggaaaaaa tggaaatttt atcagcaatg gatttagaat tagtagatct actaccaaag
     1981 tgatcaagtc aaatatagat ttgggagctt acaaccatat agtaggggct gcagtatggt
     2041 gtatgaatgg taatatgtat gatgtgagtg tttattcaaa tcatgaaacg tgtatagaaa
     2101 taattgtgct gggaatagca atcagtcatg gtgaacgtga cttttagtgt atcgttgctg
     2161 acgacataga acattctgac atgatctact caatatgtgg ggattgctgg cagtttatat
     2221 aggagtatgc atcggattgc gagatcattg tctcaacaga agagggaggt tgattatcaa
     2281 agataaagtg gtaaatccta catttgattt agtaattgtt gaggggacta gcggcacaaa
     2341 tctctacaaa gcgatgcttc tagatctata tgacacattt taagaaaatg tatttgccta
     2401 attattatgg tctttctttt gaagaaacgt tgagatgatc caaccagaga aaggtgtcaa
     2461 agaatttgac taagaataaa tggcagacgc tacctatgct catttggata gcgtcagatc
     2521 ttttatttta aggatgattt tgtgtttttt agacaccgta atttaagtaa ctctaacttt
     2581 tcaatccact atttactttt tttgtatttt cactgtctgg gtctcgaata gcgaaattac
     2641 tgatgagtct ctattaaaaa agctttttct acttgaaact atattgggtg gttgctcagg
     2701 aaggtttcga tttcttgaat tgcttgttgt ggaccattta ttggaaaaac ggcttgcagc
     2761 gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc gcagagcaat ctgcagtttt
     2821 ctttcagtca ctggttttgt gagggcgatt gcgtttccgt attttacaca atagtcaata
     2881 ttacagcttt gctcaaattg catccccaca ccgataaacg gtttgccgga ttcacaggca
     2941 gtttggacgg tcccttcccc gccgtggata aaagaaaaat caatgaattc atgcaaaaga
     3001 tgactagaca gatattctgt tattaaaaga tcttctgagt cagattgaat gtcatcaagc
     3061 agatagtcaa taggtgcaat aaccgctaga tccggttgtt tttgtaagaa gaacaaaatt
     3121 ttgcgtaaca tacgcggatt gcctgaacta cccattgcga aatagataat acgttttctt
     3181 tcttgttgct ttcgctgtat aaaagttagc acttcttcag gcaaggaagt actgagctta
     3241 gcaaaaattg gaccaacgat tcgataattt tccggcagct gttcttcttc caaaaatagt
     3301 ttaggcgttg tgatgagatt tagatcagca tccatcattt gtaaacttgt ttttggtaaa
     3361 ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg ggatccatcg ggtatttact
     3421 atacgctttt ttgtccagtg ccaaagggga ttgcttaaag ggccgaagaa acgtaactcg
     3481 tggggcatca gcgcatgctc tgattgaaaa aaaggttcac tcaaagcata gggtttaaca
     3541 tatactaaag gaatcttttt attgcgggcc gataaaaaaa ttgtcacatt cgaacctgtc
     3601 acaatcagtc gaggctcaaa cttagcaatc agactctgtt cactagtgat acgagaggca
     3661 accatttctt tggtaaaagg gtttttaagt gtacgcaact ggtcaaattt tatgatttgt
     3721 tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat actcaaagcc actttctgtg
     3781 atcaaaggag caaaagtttt agaaaagcca aagaatacac agtaataacg gtctttcata
     3841 gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat tgaatactgc aggagcaaaa
     3901 agaattgtct tcatgaaatc ctccttattg gaatgagtct atcccttcgt ttcttactag
     3961 tatactaaaa aacacagcgt tcgagtagcc tatgtatatt ttgaatatta aactgtctct
     4021 cgctgttttc acaacttcta aatttaaatt ttgtaatcaa gttgaaactc caattttcaa
     4081 aaaaacacgc aacaattttt tgatcgattt atatgttgtg ccagataaat acgagaagtt
     4141 gtgtcattaa aaataaacat gagaacataa aaaaataaaa taattatatt aattgatagg
     4201 tgtgctgtcg tcattataca cacgtaagaa agaaatagtt atgtttaaaa atattcttag
     4261 actttctcgc catgacaatt ttcactatgt gttataactg taaacgataa ttattcagat
     4321 aacacaaaaa gaaatcaagg agcagatacg ccagttgttt aatttgaata ttattttaaa
     4381 att
//
LOCUS       DADVXB010000171         4374 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.177, whole genome shotgun sequence.
ACCESSION   DADVXB010000171 DADVXB010000000
VERSION     DADVXB010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.177"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(83..1051)
                     /locus_tag="KB902_002545"
     CDS             complement(83..1051)
                     /locus_tag="KB902_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6809316.1"
                     /translation="MSKNGIIVNEWENLTALSNRRLNVQNMYTPLKMQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQYEENIAYIEILKW
                     QDGKGRIDFNPNKIGHFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRLYNKKLEQETKRKIVPPEIETWWRLELQ
                     LRRGKATDWHAMVHESLNSFASPHFLPLDVKTNDKVMIFGLIANPEMWGFLERRMKYK
                     LRDILKRESQNDELTNHLRETFSESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1498..2904)
                     /locus_tag="KB902_002546"
     CDS             complement(1498..2904)
                     /locus_tag="KB902_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBB6809317.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3126..3488)
                     /locus_tag="KB902_002547"
     CDS             complement(3126..3488)
                     /locus_tag="KB902_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809318.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3492..3830)
                     /locus_tag="KB902_002548"
     CDS             complement(3492..3830)
                     /locus_tag="KB902_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809319.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3809..4228)
                     /locus_tag="KB902_002549"
     CDS             complement(3809..4228)
                     /locus_tag="KB902_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809320.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4221..4361)
                     /locus_tag="KB902_002550"
     CDS             complement(4221..4361)
                     /locus_tag="KB902_002550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809321.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1236 a          993 c          617 g         1528 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attccgaaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcttttca aaatatctct caatttgtat ttcattctac
      241 gctctaaaaa cccccacatt tcagggttag caatcagtcc aaaaatcatc accttatcat
      301 ttgtttttac atcaagtggt agaaaatgag ggctagcaaa actatttaaa ctttcatgaa
      361 ccattgcatg ccaatctgtt gctttcccac gccttaactg caattccagt cgccaccaag
      421 tttctatttc tggtggcaca attttacgct tggtttcctg ttccaatttt ttgttgtata
      481 gccgaatctg gcgttcgctg gcacgactgc cccaataagc tgtttccagc ttcccagacc
      541 gcccataaat tggcttgaaa gaaacaggat caaccactcg atattgtgta ataaactcat
      601 caggcacatc gataatatcg caagcaatat ccgcacgtga gaaatgtggt tctagaaata
      661 aatcatgaat gaaatttttc attgaactag ctaaaaaatg accaatctta ttcgggttaa
      721 aatcaatccg ccctttgcca tcttgccatt tcaaaatctc aatataagca atattttctt
      781 cgtattggtc taataattgc cagccgttat tcccaaccgc ttttaaatag ccattgcctt
      841 cattcacccg cattaattgc tcaaaatcta aaatcaacac atcattttga gtgtgataat
      901 aaatattttc cttcagtttt ccaacgatag taattcggtc aattgaccac tgcattttta
      961 agggggtgta catattttgt acatttaacc gcctgttaga tagggctgtt aaattttccc
     1021 actcatttac gattatgcca tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgttgg tagcgttgct cgactatttt tttactcttt
     1261 tttcagttca tttgtttgct aactcaataa tagcacttct ctttagctat gcaaatatcc
     1321 aaaaaataaa accgcaccct ttgaaaaggg cgcccccaaa cttcgctaac gctaggttgg
     1381 ccaaaaaatg gactggccat tttttagcaa atgtcagctt aataggctag tggtttagcc
     1441 gtcaactcct tatcctcggc acaaaccgcc tccggtaccg ttgactgcac atcgtaacta
     1501 ccactcgatc tcatcttcag aacgctctaa tttacgctgt gagacgtttt gacgataaaa
     1561 taaggttttc tcctgctcta acacttctaa ttcctcagaa agccccatat ccttttctgc
     1621 aagaccaaaa cggatagaca aacgagtgat cgatttttga aatgcgtttt ttaatcgctc
     1681 taaacgctgg cgtaaagagc gattttcttc tttcagcttt ttattttcca cttgtaaatc
     1741 tgctaattgt tttctaccag acaaatgacg ctcttcttcc aatgtagcta catactcatt
     1801 taattctgta ttttgctcaa gcatctgtaa atattgctca ctcatgttat cagcatttct
     1861 cttggcattt gttgctctcg tagctcgttg atacaaatca acaaaatcat tcccagataa
     1921 atgatacgaa ccatcaggaa gcctcttgaa actttctaaa ggaaccatat ctttttggaa
     1981 aatgaccgcc atctcttttt ttacattcag catatttttc ttctcttctt caatcttcgc
     2041 tctctcagaa gccatcagag ccttatcacg ctcgttttct tctctttgcc tagaaatata
     2101 cctcaactca tcagaaacgc tctcacgctc ttttacagcc gtttggcgca attcagaaat
     2161 ttcactcatg atttctttgt attcgtgaat atctttaatt ttgttggtac cgacaatatc
     2221 ccttttccaa ccgtaatcat tcattaatcg ttctatagag tcaacttctt gatttctaaa
     2281 attattgaaa agcactcgac cattatcttt atcagcgtgt atcccttgtt gaaccagtgc
     2341 tttattaaag ctcggctgct tttgaacacc ccgtttataa ccttcagcaa ccggcacaat
     2401 attcaagtgc aggtgcggac ttatttcgtc attatgaata acagcattat aaacagccaa
     2461 attagggttt ctctcttgaa actccttgta atactgaacc aaaattttat tggcaatcac
     2521 tcgattttgt tcagcttgtt gtttcgatat gccagtagaa gaaccatctg ctcgatttgt
     2581 ctggaaatca tctaaaatgc ctatttgcac aataaattct cgttgaggtt ccaacttttt
     2641 atccttgcgc actttcgcta aatagtcctc gatttttcta tcggctcttt tttgtttcgc
     2701 attatatttt tctaccactt cgccaaacaa ttcctcatat ttatctgcta gattcgtctg
     2761 ctctaaataa atattttcat ccgatttcgt gaagtcaata tgcttatgcc aatcattggt
     2821 tttctggcga tcagttaact cacgattatt atgagaaata cttgtattct tcgttccttt
     2881 tttaaatgaa atactaaacc ccaagttaaa accctccttc gcgctgtcgc taataaaaag
     2941 attgtaaacc tttctgttac tctttgtcaa agagtaacat tttcctaatt gtgacatggc
     3001 tgtcacaatt ccaaatgctc tccgagggta ttcgctgtca caagtgacaa cgaaaaaagg
     3061 agccgaaagc gtgtcacgct ctcaactcct tttacgcttt attttgcttc acgcaaaata
     3121 atcgcttatc gtaaattcac gtcattaaat attgacgtaa atttactctc actcatctga
     3181 cttttcttat tcggtatcac tccgaataag ccgtcagatt catcgggata atctcgttcg
     3241 cttggcgctg atttttcatc agcaagccac tcattatcca ctgatttttc gtgttgctga
     3301 tcgtcagaaa ttgacgataa ccaccgctca aaatcagcaa aagtttcaaa cccaaaacgc
     3361 ttgcgaagag ccttgcccat tgcagcattt tctttctcaa tcaagcgttt tttctgttgg
     3421 cgaagtttcg cttgttcttt ttttaatttt tcttcttgcg ctttaatatc tgctaaagtc
     3481 attcccataa actacatctc cttttctttg gaattaataa cggaaatttg gtttaactgc
     3541 ataacatgac tcattaattt caaccaaaat tctttttctg attcatcagt tgtttgcgct
     3601 aaatgcttat gaacaaattc attagtcaaa actgaagatt ttgctagatc agcattgata
     3661 accgagttga gaacatccat cattcgttca agcatttcac tataattatc ttcatccggc
     3721 aaattcaaat aatcagctaa ccgttcatac atcaattcaa ttctatcgac tgtttcttct
     3781 ctcaaatcaa ttttatccat gtcacacctc acttccagaa ttgccaccat tttcgatttt
     3841 ttaattcttg attttctagt aacaactgat cgtttttttg ttgctgaagc aaagtcaatt
     3901 tttgttggtc acgaatcatt tccgttaatt cagaaatatg cctatctttt tccgctaatt
     3961 gttcacgcaa aaattcattt tctttttcta acgggaaatc attgcctgca tcattgaccg
     4021 gtaaatcacc agtcaattga ccaccttttg accgataaat tgaccgcaca acaccaatca
     4081 attccttgtc taacatgata accccattat ctttataccg agcaaggtca taacctgcat
     4141 tgaccagttg attgcgcact gtatttttag atatacccaa ctcatcagca aggtttttta
     4201 tggtcatttt ttctggcaaa tcagtcatta tcttctccgt tactttcagc taccccataa
     4261 acatatttaa cagcatgctt agggataatg attggggaat caattttatt atttttcaaa
     4321 atcaactcat actgcgttac atcaagtaac ttaccggaca tttttttgct atcc
//
LOCUS       DADVXB010000172         4317 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.178, whole genome shotgun sequence.
ACCESSION   DADVXB010000172 DADVXB010000000
VERSION     DADVXB010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.178"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(311..1294)
                     /locus_tag="KB902_002551"
     CDS             complement(311..1294)
                     /locus_tag="KB902_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBB6809322.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            1672..3063
                     /locus_tag="KB902_002552"
     CDS             1672..3063
                     /locus_tag="KB902_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6809323.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            3079..4119
                     /locus_tag="KB902_002553"
     CDS             3079..4119
                     /locus_tag="KB902_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6809324.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     DGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            4138..>4317
                     /locus_tag="KB902_002554"
     CDS             4138..>4317
                     /locus_tag="KB902_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBB6809325.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIF"
BASE COUNT         1438 a          709 c          757 g         1413 t
ORIGIN      
        1 tttttgtcaa aaaaaggcag aaggtgccga ctcaaaaaaa taagtcgagg ttgggacaga
       61 agtgtttaac tccgagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga
      121 atttcggctt atttaagaag aagttgcttc tgctcccacc gtttattcgt ttttaaagaa
      181 tgagacaaaa gtgtttctta cttttgtccc acgctcttat tcatgctcag agcgccaata
      241 gatacaaaat catagccaaa gtttcacgaa ccctagctgt caaagaatcg atattttatt
      301 ttaatatagg ctattttaaa ataaatggtt taaggtattc ctctacaaaa gccactctat
      361 caattatcat gggtttaaaa taagaagtga tggagataac cagattgttc ttagcgtcaa
      421 tataaagaac atttccacta ttaccaattg ctgaatatat ttcgttctca gaatctaata
      481 cccaccataa atagccatat ctcatatttt gtaagtcttc taaagcactg gttctaggtt
      541 tgaacatctc gtttatccac atgggtggta cgatttgttt tcctttatac atccctttat
      601 ttaggcataa tacaccaatt tttgccagat cacttgccga taaacacaaa ccatatcctg
      661 ccgtcccgat atttagtgga tcacaaaacc agacattggt tttaggagac ttatccattg
      721 taaactgctt atgttcttca gctgtttcag cataataatt gacatggttt ggtatcccta
      781 taggatcaaa tagatactta ttggcaaaat caacagttgt tagcttactt gtctgataca
      841 acaagccagt taatatgtgt aaacagacag tttgatagtt gaattcgccg gttatacctt
      901 ttcttcctcc caataaatct agtgatgttt ttgtccaatc ttcacttgaa cagacttttg
      961 tccatggatc gcctttacat ttgtagggtg ctttcattgt tagcaagtgc ttgattgtaa
     1021 tagcgtaaat agttttctcc ccgcgtttca ctttatactc tggaaaataa tctaatactt
     1081 tatcatcgat acttttgatt aatccttgct ctaaagcaat gccaatcagc aaagatacaa
     1141 tacttttcgt tgctgacatg atatgacaag tatcgtcttt tttataacca ttccattcat
     1201 ctgtataaac ttctacccca tccttatatg cgacaatttg acatatattt ggttgtcgaa
     1261 aaccaataaa atcatgcaac tcttgtttat tcataagata ttacctcact ttcttctata
     1321 agcataatgt cattaaaaat cgatttcaat tttttcgatt cttcacgtaa tacaggtatt
     1381 cttatggact agacagcgct ttgggaagat ggattctctg aaaaatataa aggttcactt
     1441 tatgagtgga taaaaaaagc agcaaatact tcgacttctt taatttacca acattagtga
     1501 aaatcgattc atctggagat ttgtaattta gagtccttgt cttgattaga ggtgtataaa
     1561 gctttttatt agacattttt aaattccatt acaatttgct tataaactag gtttttaaag
     1621 gtgactatgg taagataata gagatattat tttgtgatta ggagtgtata tatgaataaa
     1681 aatggagaat ggagtgctgc acgacggata ttcattatat taatggatgt tattgtatac
     1741 aatgcagcaa tatatagtag tttcttactg aagtttcgtg gagagatccc attacgaaat
     1801 ttagaaactt tccaacactc agcaattatt atttcagtga tttttattgc gttgaacatt
     1861 ttgttgggtg catatgtttt ttataatcga atgatcagtg acatcgtgtt tgtcacagtc
     1921 atcggtcagg tattgatgac actagggatc atggtagtga cttttgcggg ccgctggttt
     1981 gcttttccac gtcttgttat cttactttca tttgttctcg gtacgctttt cttaagtatc
     2041 tatcgtattc tcgtatataa actttattta cgcgtaagtc gagataaaaa ggtcgtcatt
     2101 attgggttag aaaaggatgt cgcaccagca atccaaaatt ttggttcaaa gaaaaacaac
     2161 aaacataaag tcgaagcagt cattcttgat aactattatg caaacatcaa aaatatgatt
     2221 aaagacatcg atattgtcta tcttgcttct catatcgaag aaactgaaaa aatcaaaatc
     2281 tatcaattag ttactaaaaa tgaaaaaaaa ttgtttttga atacaacatt tgaaaacttg
     2341 acattgatca atccaaatat tatgaatttc gaagatgaaa gtattattga agcatctgga
     2401 tttagaatcc aacctgaata tgaactattc aaacgtttgt ttgatatcat cgtttcactt
     2461 gttttattag ttattgcttc accatttatg ttattcacag caattttagt caaagtgaca
     2521 tcaccgggac caatcatcta taaacaagtg cggatcacaa aaaatcaaaa ggaattttca
     2581 atctataaat tccgctcgat gaccgccaca gccgaagcaa aatctggacc agttttagct
     2641 aagagcaatg atgcacgagt aacgcctgta ggtaaattta ttcgagctgt ccgctttgat
     2701 gaattaccac aaatcttcaa tgtgctgaaa ggcgatatgt cgatcgtagg accacgtcct
     2761 gaacgtcctt tcttcgtcga tcagttcaat gcagaaaacc cttattacta cttacggcat
     2821 aatgttcgtg ctggtatcac tgggtatgca caagtctatg gaaaatatgt ctctgattac
     2881 aacagtaaat tacgttttga tttactttat atcaaaaaat attcattgat gcttgattta
     2941 aagatcttgc tgcaaaccat caagatccta tttgataaaa tgtcctctca aggacttgaa
     3001 gaagacgaaa atgtgatctc attggcagaa attgcttttc cgaatgaaaa aatctttcgc
     3061 tagttgggag gcgtaaaaat gaacaatccg aaattcagca taatcgtacc agtatacaat
     3121 gcagaagcaa ctattggtcg aacgattgat attctaaaag aattggatta tgaagagtac
     3181 gaagtcgttt tagtaaatga tggatcaaca gatcaaacac aggaaatcat tcaagaactg
     3241 attgaaaatg atgaacgttt tgaattgatt actacgacca atcaagggcc cggattagca
     3301 agaaacgaag gaataagaca gtcaaaagga gaatatctct tattcttcga tgcagatgac
     3361 acgccagtaa aaacgatctt gtcagattat gatcatttgc tagaaaagag tccaaaagcg
     3421 gatcttgttg ttagttcgtt tgtttttcgt acaatggacg agggaagaat cgtttccgaa
     3481 aaagaaaact tagttacaga atgtcactat ctaactcacg aagagtttat aaaagacatg
     3541 tatcagttaa tgaatgaaca gttgatgtat gttgtatgga acaaatgcta tcgtagcgat
     3601 attctgaaaa ataaccaaat tctatttaaa acttataata gttgtgagga tcgaatattt
     3661 aacttacatt attatgaata ctgtcatcaa gtgatcatga acccaaaagt agaatatatt
     3721 tatgaatttg aagatgggaa ggggatcact aatcaatacc gacctaacaa gttcgaaaca
     3781 tttaaagaat tctattcatt agcaaatact gtaacagacg atattaataa agacggtatg
     3841 gcggcgcttc ttttaaaagg gacaacttca gttatttttt ctatttatag tacctctgca
     3901 agaacttcaa aagagaagaa agacgaagca aagcagatat tgagtgatcc agtgatccga
     3961 gaagccaagc aaattgctaa gacggattct tcagcaaaaa aaataacaaa gttgctttac
     4021 aatatgccag ctccactatt tttatctgct gtaaaagttg gaagcttcgt tgaagtgaaa
     4081 atgccagggt taatggctgc tttgaagcga gtatattagt taatggagga aaatataatg
     4141 aaaagaattt tgcattttca gggacgaatg ggtttaggtg gagcagagtc tttcatgatg
     4201 aatttatatc gtaaaattga tcgtacaaac tatcaatttg attttttgat ttatgaagat
     4261 tatgcagatg ttcaagacta tcattcagag attgaaagat taggaggccg tattttt
//
LOCUS       DADVXB010000173         4303 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.179, whole genome shotgun sequence.
ACCESSION   DADVXB010000173 DADVXB010000000
VERSION     DADVXB010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.179"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..236
                     /locus_tag="KB902_002555"
     CDS             <1..236
                     /locus_tag="KB902_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6809326.1"
                     /translation="DVSMLEPASQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASI
                     TADDSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            242..928
                     /locus_tag="KB902_002556"
     CDS             242..928
                     /locus_tag="KB902_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809327.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            932..1678
                     /locus_tag="KB902_002557"
     CDS             932..1678
                     /locus_tag="KB902_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809328.1"
                     /translation="MDHRSYYAIIPANVRYDDSLIPSAKLLYGEITALCNEKGYCWAS
                     NEYFANQYGVRKSTIQNWLKSLEEKGYIYREVKYKEGSREIEARYIRILGGGHPEKWV
                     GGHPEIYQDNNTSINNTFNNTKEYIRELPPSKKSKAKPIRHKYGEYKNVLLSDEQMEK
                     LKIEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGRR
                     EKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            1690..1959
                     /locus_tag="KB902_002558"
     CDS             1690..1959
                     /locus_tag="KB902_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809329.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            1965..2129
                     /locus_tag="KB902_002559"
     CDS             1965..2129
                     /locus_tag="KB902_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809330.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECGDG"
     gene            2122..2427
                     /locus_tag="KB902_002560"
     CDS             2122..2427
                     /locus_tag="KB902_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809331.1"
                     /translation="MDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKTKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSSWIDSKGRQFRYVEEKKC"
     gene            2421..2711
                     /locus_tag="KB902_002561"
     CDS             2421..2711
                     /locus_tag="KB902_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809332.1"
                     /translation="MLDMRIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            2711..3028
                     /locus_tag="KB902_002562"
     CDS             2711..3028
                     /locus_tag="KB902_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809333.1"
                     /translation="MEFVDLNVRGIKCDNPECDYSDMAVKYENYPQWLNKPCPKCGAN
                     LLTQEDLDATEQLMEIVNLTNEILKDSGLEKQDMNKYIVPVEANGTGELSFGEIKKLE
                     EEK"
     gene            3025..3840
                     /locus_tag="KB902_002563"
     CDS             3025..3840
                     /locus_tag="KB902_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6809334.1"
                     /translation="MNENKLIKLGVAGVVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKEHGWVTVNGADTVVTDETGK"
     gene            3979..4293
                     /locus_tag="KB902_002564"
     CDS             3979..4293
                     /locus_tag="KB902_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBB6809335.1"
                     /translation="MDLITQYSEIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
BASE COUNT         1636 a          665 c          966 g         1036 t
ORIGIN      
        1 aagatgtctc gatgcttgaa ccagctagcc aaagaagcaa aaagctattc ttggatgctt
       61 tacaactggt tgctaacaag tacgaaaaat caattgatga agcaattgtt gcattgactg
      121 atgcagcttc cataaccgct gatgacagta aatggaccaa gagagacttg ggcattctaa
      181 aacgaggcgt taactggatt gaagatcagt acagagaaga aacaaaagag aagtgatatg
      241 agtgtttaaa ccattaatcg attcatattc agcggttctg aaaaagttca aaggaaaaga
      301 cataggtgca acgatcaatg aagaagtgaa cattgatcga ctaaagacga tgtatgacgg
      361 ctacgatggc gatcgagtca ttgaaattcg ttttattgat cctagacgtt tcaccgtaca
      421 gcaacgaaac ttcatctatg cgctgatagg cgatattttt atcgatacag gcatgccaac
      481 ggacttctgg aaggaattct tctacttccg ttttgaaggc gtcacagggc gcaaaataag
      541 cctcaaagac gaatcgaata cgactgtgag tgatgctaat gtcttagcaa atatcatttt
      601 agatttcatc tttgaacacc atattccttt caaagaaggc tatgagattt taccagcgaa
      661 tcaagagtat tacttctaca aatgcatcac aaaaagagtc tgctgcatct gtggcaaaac
      721 aggagctgat attgatcact ttgacaaagc tttaggaaga cgaaagcgca aagaagttga
      781 tcattcagag tacacatttg cagcactctg cagaatccat cacacagaga agcacaagat
      841 aggtgtgatc aatttcaaaa ataagtatca aatcaaaggg atcaagttaa accaggaaac
      901 aatcaagaaa ttaagaatcg gaggatgaaa agtggaccac agaagttatt acgctatcat
      961 acctgcaaat gttaggtatg acgattcttt gatacctagt gcaaaacttc tttatggaga
     1021 aatcacagct ctatgtaatg agaaaggtta ttgctgggct agcaatgagt actttgccaa
     1081 tcagtacggt gtaaggaaat caacgattca aaattggctg aaatctcttg aagaaaaagg
     1141 ctatatctat cgagaagtga agtacaaaga gggtagtaga gaaatcgagg ctaggtatat
     1201 cagaattttg ggtgggggtc acccagaaaa atgggtgggg ggtcacccag aaatctatca
     1261 agataataat acatctatta ataatacatt taataataca aaagaatata taagagagtt
     1321 accgccttcg aaaaaatcga aggctaagcc catccgtcac aaatacggag agtataaaaa
     1381 tgttcttttg tcagatgagc agatggagaa actcaaaata gaattcccta atgactatca
     1441 agaacgaata gaacggctat ctgagtattg tgaatcatct ggtaagactt ataaaaacta
     1501 tttggcaact attcgaagtt gggcaaggaa agaaaaaagt gaacctaaga acgcaagcag
     1561 tggatacaag cgcacaggaa gacgagagaa gcttcctgaa tgggcaatcg accaagaagc
     1621 ctatcttaag aaaaaagcgc tagaacgagc taatagacaa tcaaaagcac cattctaaga
     1681 ggtggaaaat tgaagatcga ttatctagaa ctaattaatg aaatagcaaa gtataaaact
     1741 ggtgaggaaa tagaaattct gagagacgta tatgatcaac tcgaagaagc tggaattgaa
     1801 ggaattaaga atgatcgttc gagttggagt aagctcagat actatttcgc actttatatc
     1861 gatggaacac aattaagaaa tttagcatat accaaattac tatttgttga ttgtgttaaa
     1921 ggcttgcaaa aacatcttaa tgaacttgag caggtgtaaa caagatggac ctaaagacat
     1981 ttacagcaca gatcgaatta atgcatcaag aagctttaag acaaagtgta tcgtacgaag
     2041 acaagtggct caacacgttt catggcggac gtgagagcgc acttgatcaa gtactcaaat
     2101 tattgaaagg agaatgtggg gatggataaa aaagcggcaa tgaaacgaat tgctgaatta
     2161 accaagtcag aatcttggca agaagacaaa gaaatagttg cagaagtcca aaaactcggc
     2221 aaatcaatgt ggactgaaaa aaccaaacgg aaaacgccga gaaagattgc aatctggcat
     2281 ggtgatcgaa ttctagtaac aggtactgct gaacagttat ctgaaattac tggattaagc
     2341 aaaaacatta tttgggatag agctaggagc tcatggattg attcaaaagg acgacagttt
     2401 aggtatgtgg aggagaaaaa atgctagaca tgagaatcga agattatcga attaccagtg
     2461 attctagaaa cattgtccta tcaaaggtaa gacgagatga ggaaggaaat atccgctaca
     2521 cagaagcaaa agaagaatca cgagcagata tcggatactt ccaaactgtc tcatcgtgtt
     2581 tgaaggcgat acaacgcgat tacgtgttaa gtgaagaaag aacgataaaa agtattatcg
     2641 agtacaaaaa agcgttagaa aacatcacta gacagtttga acaggcatgt gagattgagg
     2701 aggagaaata atggaattcg tagacttaaa tgtacgtggg atcaaatgcg ataatccaga
     2761 atgtgattat tctgatatgg cagtaaaata cgaaaattat ccgcaatggt tgaacaagcc
     2821 atgtccgaaa tgcggcgcta atcttctgac gcaagaagac ttggatgcaa cagagcagct
     2881 tatggagatt gtcaatctta caaacgagat cctcaaagat tcaggattgg agaagcagga
     2941 tatgaataaa tatatcgtac ctgtagaagc gaatggaacc ggtgaattgt catttggaga
     3001 aataaaaaaa ctggaggaag aaaaatgaac gaaaataaat taatcaaact aggtgtggca
     3061 ggagtagtaa tagtaggtat tggagttatc ggaggattta agtttttcga aaaaattgat
     3121 aacggatatg tgggtgtgcg ctattcaatg aatggcggta tcaaagatga agcactgacg
     3181 caaggtgtga aatttgttgg gattgacaaa gtgatccaat atccaattcg cttgcaaact
     3241 atccaatcaa aaaacatttc agtatcaaca agcgatggca aaaagacaac gattgatatc
     3301 aaatatgact acaaagttga ttcaactaaa gcagcaaaaa tgtacaaaga atttgggaat
     3361 ataacttcgg aagatatcga aagtggatgg ttaaaatcta agcttcaaaa agtagcgcgt
     3421 gaagtttatg ccaaatatag cctgcttgat gtcctttcag gagattcctc taaagttgaa
     3481 gctgaggtac taacgaactt tgctaaatca gttgaatcta aagggtttga agtcgaagac
     3541 gtaacacttg gtgttccaga tgtcgataaa gaaacacaaa aatcaattga tgcgatcatt
     3601 cgagctggtc aagaaaatga aaaagcgaag ctagatgcag aaactgcaaa aactcaagct
     3661 gatagtgaag cttacaagaa aacaaaagct gcagaagcgg aagctgaatc aaaccgtaaa
     3721 gttgccgaat ctgtaacaga taatttaatt cgttatgaag aagctcaagc tcgaaaagag
     3781 catggatggg taacagtaaa cggagcagat actgtagtta cggatgaaac aggtaaataa
     3841 tatgggattc tttatagcta aaattctctt gttcttaggt ttggtaggag tggcatatct
     3901 cgtgtatgcc ctcctttcca aaactgatga caaagaagat gacaacgacg atgaaatgaa
     3961 attttaggag gagaaataat ggatctcatt acacaataca gtgaaatcat cctcaagaaa
     4021 atcatgatga agattcagaa agataaaaaa tcaaaagaac gagcggaatt agttaagttg
     4081 gaaatggctg aaacaggagc aggagtgcga agtagcaggc attggaaagc agcagcaaac
     4141 attgaattct attacaacga aattcaaaaa gggttcgatc agatgcgtga gctggatcgg
     4201 caaacaaatt ggagcaagaa acttcatcaa gatcgtttca aatttgtaga aaagtataga
     4261 gagatactga atgagtattt cgaggaggac tagatgttta att
//
LOCUS       DADVXB010000174         4146 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.180, whole genome shotgun sequence.
ACCESSION   DADVXB010000174 DADVXB010000000
VERSION     DADVXB010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.180"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(30..1796)
                     /locus_tag="KB902_002565"
     CDS             complement(30..1796)
                     /locus_tag="KB902_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809336.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1756..3510)
                     /locus_tag="KB902_002566"
     CDS             complement(1756..3510)
                     /locus_tag="KB902_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6809337.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3620..>4146)
                     /locus_tag="KB902_002567"
     CDS             complement(3620..>4146)
                     /locus_tag="KB902_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBB6809338.1"
                     /translation="SLVIYFFSIMVSSIGGAFGHSISPGIFGLLSGIIFVYISYNYPR
                     KGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVFGYDRAIPQVASWALM
                     QLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGIWGIISVLVVASLSMI
                     GVLIGRKVLKKYKK"
BASE COUNT         1394 a          790 c          584 g         1378 t
ORIGIN      
        1 aattgtaggt taatttaaag cctatttcat catcgtgatt gagcttcttt ttcatagacg
       61 aatttctcag atagtttagt tttctttatg agatttttgt atatttctga ccttcgatac
      121 aactcactat gagtaccttg atcaactatt tttccttgat ccatcactac aattttattt
      181 accttttcaa tagacttcaa gcgatgcgat ataattagta ctgtcttatc ttgtattaaa
      241 cgatttaaac tttcctgaat acgtttttca ttttccgcat ctaaactggc agtaatttca
      301 tctaaaatta aaattggcgc atttttcaaa aaagcccgtg ctatggatag gcgttgtcgc
      361 tctcctccag aaagtgaact tccgttttct ccgaccaatg tatgataacc gtcaggtagt
      421 ttttcaataa agtcttcgca gttagctaaa cgagctgctt ttttcacttc ctcatctgac
      481 gcttgactat ttccaatacg tatattttcc aaaatacttg tattaaacaa agttacctct
      541 tgaaaaacaa tagcgatttt gctaaacaaa gaagctggag atacacgttt aatatcatac
      601 ccatcaatta aaatacagcc ttcatcataa tcatacagtc tagacactaa tttcaagata
      661 ctagttttcc cggaaccact agcacctact aacgcagtca cttctccttg tttagccgta
      721 aaagagatat gatctaaaat tggggtattg ttatcatatg agaaagagac atctcgcaac
      781 tcaatgtcaa aagatttcag aggactatct gatccctctt ggatactggt ttccttcata
      841 gctctaattc gctgtatttt aggagctaaa taaaatattt caagcactgc ttctttcata
      901 gaatcgaagg aatcctttat ttttattgcg gctagtaagt aaccaacgac gtagagtata
      961 gtcacttcac ccgttaacag taagtgaaca cctactagaa tgactactgc taaactaaca
     1021 tatgagaaaa tagaggataa ggccatgact gaaaaagtac ttaattctac ctttaaatga
     1081 atcctttcac tctcttccat ttttttgaaa agtctgtctt gaactttttt agatagatta
     1141 aagctattaa tctcttgctg caattctata gtttcttgaa attcttccga gttttctctc
     1201 aaagtatcgt aatatttagt attggctttc gtttgggatt tctttgataa caagattaag
     1261 acaaaactaa ataacgttgg caaaataaca gctaatccca ttttgacatt accaaccaaa
     1321 agcatcactg aaataaaagg gaaaaacaga gccataccgc cggctttagg tattgcatga
     1381 ctcatcgcat gctcaatacc ttcaacgtca gacatgatag tttgagataa atctgataaa
     1441 ttatgttttg aaaaatagga taatggtaaa tttgacaaat cgtctgcaat ttgcattctt
     1501 aaatgcgcac tttctttata agtactatta tataagtttt catactccct atctaacaac
     1561 caatacatga aaagcaaagt aacgaacgat actgtaaaat aaagccaagg cggctttaca
     1621 ttttctaaaa ctaattcgtc tatcagcatc attataatga atgctggtac catattaatg
     1681 cagtatacaa aaaagctaga aatagatgct ttaaccaaat cttctgcgcc ctgattagtt
     1741 aaagcgaatt tgtttttata aaaacttttc attgtcaagc ctccaatcat ttgcattctc
     1801 ataattagtg accaattgtt tatacacttg atgtttagcc attaattcat tatgatttcc
     1861 acgttctact attttccctt ctgacaagac aagaatttca tctacagatt taatgctgga
     1921 taatcgatga gctatcataa taactgtttt ttctttcatc agatgttgaa aagccttttg
     1981 tagttcatac tcattatctg gatcaataga tgcactggct tcatccataa taacaatctt
     2041 tgcatctttt aaaattgctc tggcaatagc tatacgttgt ttttctcctc ctgacagata
     2101 aactccttta ctaccaatta aggtatgctc tctttcggga aatttttcta aaatcgattc
     2161 gcaaccggct aatcttagcg cgtcaaatac tttacttgct ggcgcttgag gatttgctat
     2221 agaaacgtta tcgtaaatac tctgattgaa tagtttcgta tcttgaaaga caaaagcaat
     2281 tgtgttaata attgtgtctt ttgaatagtg atttaaaggc ttaccaccaa ttttaatctg
     2341 tcccttatcc acattgtaga aacctgaaat tagtttagct atcgtactct ttccgcttcc
     2401 tgattttcct actaatgcat aaattctttt ttgttctaaa actaagttga aattttctaa
     2461 aacacactct tctttgtatg aaaagctgac attttcaaat gcaatgtcac aatttttaat
     2521 ctgtgtctcg ttcccatatt ttagttggtc ttgcttcatt tctaaataaa gggagtctag
     2581 tgtttcgact gcatatcttg cttcaaacaa gtgcatactt acatacatta ttctcatgaa
     2641 agaaacaaaa ataattccac ttaaaaaaaa caacatcaac aagtcaacag ctaatatctt
     2701 gggagtggta agagaagtta taaaaaaggt tataggaact atcaaaatgc aaactatgcc
     2761 aaaaaatagc cattgaaaaa gaacaaaagg tgttttccca ctcaaagaat acttatatgc
     2821 aaacttagca taatcgttaa ttgctttatt caaggcttta aatgatgtta ctttagcacc
     2881 aaatatcttt ataacttgaa ttcctcggat atattctacc gtttcagagc ttaacacatc
     2941 taacgattct tgatattttt gaataaaatt tgtattctct gtcattttct ttaacaagaa
     3001 tacaccaatt actaacatgg cgattagaac caatccaatt ttaaaattaa tgaaaaagcc
     3061 taaggcaact gataaaacag gtgttactat ggcttgagca ctatctggaa tcaagtgagc
     3121 aattgccata tgtgttttag ccgcgttgtc atcaattgtc tttcgaatat atcccgaaga
     3181 atttaaatca aaaaaacgaa aacttgcttc tgttaaaccg ctaattccct tttttctcaa
     3241 attagtctct aagcgaaacc caaggatatg agaaaataag ccagaaaaaa tataaaataa
     3301 agctcctaaa gttaaccaag caacagtttg aaccgcataa ctcttagcta aatattcatc
     3361 tcctacaata attagagact taagaaattt gtaaatactg taatatccat agactgttaa
     3421 tacgacagaa aaatcagaaa ataaagtggc taaccatccg tagtatttca ttttagggac
     3481 ataactaaat aattttttgt atactttcat tttttcctcc cccgcattca atttcttctc
     3541 ttattcgttt acaactgtta atgctttccg taatagcgta aattagagat gtacaaacag
     3601 atagaaggta aactacgttc tattttttgt atttttttaa gacttttctt ccaatcaata
     3661 caccaatcat agataaactt gctacaacta acactgaaat gattccccat atacctaccg
     3721 catagtggat cattgcatcc attgttgcag cagattgtcc tttatctatc caatcttgac
     3781 gaaaacgatc tgtaaagaac catataggaa tccactgtcc ggcagcactg cctaattgca
     3841 ttagagccca agacgcaact tgaggaattg ctcgatcata tccaaataca gatagaataa
     3901 tatcagctaa gatcgccata ctaatcgaac tgataaacca aggtaagtac gccccgccca
     3961 ttaacgtaaa aaataacaat aaaacaattg tgtaaatagt aaaaattcct tttctagggt
     4021 agttatagct aatataaaca aatatgattc cagataataa tccaaaaatc cctggggata
     4081 tgctgtgacc aaacgcccca ccaatactac taaccattat tgaaaaaaag taaattacta
     4141 gggaaa
//
LOCUS       DADVXB010000175         4119 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.181, whole genome shotgun sequence.
ACCESSION   DADVXB010000175 DADVXB010000000
VERSION     DADVXB010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.181"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..108)
                     /locus_tag="KB902_002568"
     CDS             complement(<1..108)
                     /locus_tag="KB902_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809339.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYEL"
     gene            complement(261..548)
                     /locus_tag="KB902_002569"
     CDS             complement(261..548)
                     /locus_tag="KB902_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6809340.1"
                     /translation="MSINTFVYPYPINVFIISRLGMTVEQFCELHGYKQSTVASWVTR
                     NRAVKTLPCDFLYCLSLSSGWSMDDVYRHLLVLEGRFLKSIDPKKKKEQVD"
     gene            complement(686..2185)
                     /locus_tag="KB902_002570"
     CDS             complement(686..2185)
                     /locus_tag="KB902_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6809341.1"
                     /translation="MAASLDVVYSTVLQNGIRKFKYKNSHLKPVSFSDQSGKGAIFAY
                     RSKEHMIEGIGLVITSEEGVIENNNRFTHWTPNVFRYGTYADEARMFTKGHSEDNLRQ
                     INTFFVDFDTLDPNFDYGEIILASHEIGFMPTMILRTPHGFQAFYVLDKPAYVTKKSN
                     FKVINVAKMISKNLRNKFSNDYRFPVDVNANHFGITRMPSEENVLFFEPQYRYSFEEW
                     IDWSMREDADKKAEIKNVFVLPSTQEFRQVDEPWFQLLLKSQKIQGEKGVYGRNNVIF
                     TLSLAYFSSGYEVEACELTMLEFNDRLANPLSDRELTRIIRSAYSGKYQAAHREKIVL
                     LCQEWVDVNLSEEQLFNKKRGWWKFKKERAVRKYSHSHEWAEDLLSYLNEQSYEEQPY
                     IISTKKELTERLKIPKRSLDKVLKQLREENKIHFRVRAGRNGGIMLASIHGLMRSVIR
                     LKKESQGPYFAAISEAFGREYTFIQTALKRLIEPNKIGVQTDLFMIDTG"
     gene            2862..3683
                     /locus_tag="KB902_002571"
     CDS             2862..3683
                     /locus_tag="KB902_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6809342.1"
                     /translation="MGKVYVVGNFKGGVGKTKSVTMLAYESAVINNKKTLVVDLDPQG
                     NATSILAKTGELEEITKSITTGFEEGDLSTQITPIMSNLDLIASNTTFRNLTKILMNR
                     FPNDEIKQITYLKELLKPLKEVYDAIYIDVPPTISDYSDNAMLAADYCIIVLQTQELS
                     LDGAQTYIAYMQYLADTYDNDLQVLGIIPCMLRPGGRVDTKVLDQAKELYGGNVLDTI
                     VKYQERLKVYDVEGIRVSYSYTGKPDGWDIKAHQVFIDVLNELDRHEEILESLED"
     gene            3686..4090
                     /locus_tag="KB902_002572"
     CDS             3686..4090
                     /locus_tag="KB902_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809343.1"
                     /translation="MSENFKPIISNKNNKSSLQSKKVEIKGKTDFGRTSSITPINNTN
                     TETIKKESITNPTAKDKRFSATLTQKVSPSVNLKMNTLRPFLGELENMPKATINEIVD
                     LVIDSYVNTRLSTRQQEAFKAMYETQLKMLNK"
BASE COUNT         1338 a          775 c          688 g         1318 t
ORIGIN      
        1 tagttcatat tctcgaatga tttctacacg tggctttcca gctaagtaaa gattgacgat
       61 ttgttgcttg aattcttgtg aaaaagttct tcgtgttctc ttagacataa aaattcctcc
      121 tggtatgttt tcttctagtc tacacacctt aatttttctg tctagttaat tgtagcctat
      181 ccaataccat aataaatctt caaaagaaca gaccattctt tgattctatt aagaacagat
      241 aactcctcct ccgtcatcaa tcaatccacc tgttctttct tcttttttgg atcaatactc
      301 tttaaaaacc tcccctccaa caccagtaaa tgacgataaa catcatccat cgaccagcct
      361 gaagaaagac taagacaata taaaaaatca caaggtaacg tttttactgc acggttcctt
      421 gttacccagc ttgctactgt actctgctta tagccatgca actcacaaaa ttgctctact
      481 gtcataccta accgcgaaat aataaataca ttgatcgggt agggatatac aaaggtattg
      541 atactcatag tcagaaagac ctcccaccat attattacgt ttgcgataat agtactactc
      601 tttcttaaga ccagcaagca aggcggagaa aaaagaagga acgtatcata gatataatgt
      661 aataggcaat ttgcaccttt taatttcaac ctgtatcgat catgaacaga tctgtttgta
      721 cgccgatctt attgggttct atcaagcgtt tcagtgctgt ctggataaac gtgtattctc
      781 ttccaaaagc ttctgagatc gcagcgaaat aaggcccctg gctttctttt tttagccgga
      841 taacggagcg catcaatcca tgtatcgaag ctagcataat acctccatta cgaccagcac
      901 gaacacgaaa atgaattttg ttctcttctc ttaactgctt cagtactttg tccagggaac
      961 gttttgggat ctttaaacgt tcagttaact ctttttttgt agaaataatg tatggttgtt
     1021 cttcatagga ttgctcattc aaataggaca gtagatcttc tgcccattca tgactatgtg
     1081 aatacttgcg aacagctctt tctttcttga atttccacca accccgtttt ttgttgaata
     1141 gctgctcttc agaaagattg acatcgaccc attcttggca taataggaca attttttctc
     1201 tgtgcgctgc ttgatatttt ccggagtaag cggaacgaat gattctggtt aattctcgat
     1261 cagataaagg gttagccaag cggtcattga attctaacat cgtcaattca catgcttcta
     1321 cttcgtatcc tgacgaaaag tatgccaaag acaaggtgaa tatgacatta tttcgaccat
     1381 atacgccctt ttcaccttgt attttttgac tttttagcaa tagctggaac cagggttcat
     1441 ctacttgacg aaattcttga gtagatggta atacaaaaac gttcttgatc tcagcttttt
     1501 tgtccgcatc ttctctcatt gaccagtcga tccattcttc gaaactataa cgatactgtg
     1561 gttcaaagaa taaaacattc tcttcagaag gcattcgtgt gatcccaaaa tgattggcat
     1621 ttacatcaac aggaaaccga taatcatttg aaaatttgtt tcttagattt tttgagatca
     1681 ttttggccac attgatcact ttaaaatttg atttcttcgt cacgtatgca ggcttgtcta
     1741 gtacatagaa agcttgaaat ccatgcggtg tacgtagaat cattgtcggc ataaagccga
     1801 tctcgtgact ggccaagata atttctccgt agtcaaagtt tggatccaat gtgtcaaaat
     1861 caacaaagaa tgtattgatt tgacgtaaat tgtcctcaga atgacctttt gtaaacattc
     1921 tggcttcatc agcatacgtt ccatagcgaa atacatttgg tgtccaatga gtgaatcgat
     1981 tattgttttc gatcacccct tcttctgaag tgatcactag tccaatcccc tcgatcatgt
     2041 gttcctttga acggtacgca aaaatggccc cctttcccga ctgatcacta aaagagaccg
     2101 gttttaggtg gctgttttta tatttaaatt tacgaatacc attttgtaat accgtcgaat
     2161 atacgacatc caaagaagct gccatgaatt tattccttcc caaactaaaa gagaacacaa
     2221 ataatcttaa agatttgtgt tctcccaata gcttagaagt cttaaatgaa tgacaaaata
     2281 agcgtgtata tattgagttg ctcgtcaaaa aatggtagaa taagtctgta agttcggatt
     2341 gtcagtccga aagacttatc aaaatcacat aagtggtttc cagccactta cataactacc
     2401 gagacgagcg agaacacata ggtttgtatg tgattcagaa aaataggtga ggtccaattc
     2461 acttattttt ccgtctcttt tttactgttt atttttcttt tagactacag aacattcttc
     2521 aacttgtaaa gaactatttt taacaatggt ttgcaacagt atacttttga acttttttaa
     2581 tggtatacca gtatactttt acacttatta cggtgtatca gtatactggt atactttttt
     2641 cgttttgtga ttaaagtatt tacatatcgg tgcttcctga atctatatag gaactttttt
     2701 atattatttc ctttaaattc gcagtatacc agtatactta ataacacctt tagtatactg
     2761 gtatactttt acaccaatct acttttgcaa ttattttctt tacaagtaaa ctccacactg
     2821 gtatacttat aatatattat taatcaatcg gaggtctatt catgggaaaa gtatatgtcg
     2881 tgggaaattt taaaggcgga gtaggaaaaa ctaaatcagt aactatgctt gcatatgaaa
     2941 gtgctgtaat caataacaaa aaaacattag tagttgactt agatccacaa ggaaacgcaa
     3001 cgagtatttt agctaaaaca ggtgagcttg aagaaattac aaagagtatc actactggat
     3061 ttgaggaagg agacttaagt actcaaatta cacctatcat gagtaactta gacttaattg
     3121 catccaatac cacctttaga aacctaacaa aaatactaat gaatcgtttc ccgaatgatg
     3181 aaattaagca aattacctac ttgaaagagc tactgaaacc attgaaagaa gtctatgacg
     3241 ctatttatat agacgtgcca cctacaatat ctgattatag tgataatgct atgcttgcag
     3301 ctgattactg tatcattgtg ttacaaactc aagaattatc tctggacggt gctcaaacct
     3361 atattgctta catgcaatat cttgcagaca cttacgataa tgatttacaa gtactaggga
     3421 ttataccttg catgctaaga cccggcggac gagtagatac taaagtactt gatcaagcaa
     3481 aagagttata tggaggaaat gttctggata caatcgttaa gtatcaagaa agattaaagg
     3541 tttacgatgt tgaaggtata cgtgtttcgt attcttatac tggaaaacca gatggatggg
     3601 atattaaagc tcatcaggta tttatcgatg ttttaaatga gttagaccga catgaggaaa
     3661 tactagaatc tctggaggat taaatatgtc tgaaaatttc aagccaataa taagcaataa
     3721 gaataacaaa tcttctttac aatcaaaaaa ggtcgaaata aaaggaaaaa cagattttgg
     3781 tagaacctct tctatcactc ctataaataa tacgaataca gagactataa agaaagaatc
     3841 tattacgaat ccgactgcaa aagataaaag attttcagca accctaacac aaaaagtatc
     3901 gccttctgtt aatttgaaaa tgaacactct tagaccattt ctgggcgaat tagaaaatat
     3961 gcctaaggcc acaattaatg agatagtaga cttagttata gatagttacg taaacacacg
     4021 gctatcaaca agacagcaag aagcatttaa agcaatgtat gaaactcagt tgaaaatgct
     4081 taataagtag aaaagtatac cagtatactt ttctactta
//
LOCUS       DADVXB010000176         4000 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.182, whole genome shotgun sequence.
ACCESSION   DADVXB010000176 DADVXB010000000
VERSION     DADVXB010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.182"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1076
                     /locus_tag="KB902_002573"
     CDS             <1..1076
                     /locus_tag="KB902_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6809344.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
     gene            complement(1212..1406)
                     /locus_tag="KB902_002574"
     CDS             complement(1212..1406)
                     /locus_tag="KB902_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809345.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYPFV"
     gene            complement(1553..1888)
                     /locus_tag="KB902_002575"
                     /pseudo
     CDS             complement(1553..1888)
                     /locus_tag="KB902_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1900..3492)
                     /locus_tag="KB902_002576"
     CDS             complement(1900..3492)
                     /locus_tag="KB902_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809346.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALDDFYIPEGETFSESKTDQEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYVVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYRNLPEKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKNLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            complement(3512..3934)
                     /locus_tag="KB902_002577"
     CDS             complement(3512..3934)
                     /locus_tag="KB902_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809347.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
BASE COUNT         1126 a          797 c          628 g         1449 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttgactta
     1201 tcaccattag actaaacaaa tggataatct tctgccgcat cgacgaacgt cttcgtagtc
     1261 agatttaacg ttaaaatatc gccactttga taagcttttg cagctttgtc tgtgactaca
     1321 aaagctctgc ctgtttgaat ttctgtcaca aaaacgagat tgtctctgct tttttcaaca
     1381 acaactccaa tagttgaata agccatttct gcttcctccc ttctctttct tttgatataa
     1441 tgtagtcgga aatcgcacca ctcaatgaat tggcggaaaa caattcagtg aaaaaaaaga
     1501 gtcctggaca atcacgttca ggactctttt acttctttta ttcacttaat aactaacact
     1561 ctgtgagtga aatagactct tttatgcttt tacatggaaa gttattgatt ccctcttcat
     1621 tcatttccca agtagtataa taaggtgtta acttggcctc atattcttga atgataaaat
     1681 atttttcacc gttcacatga ttacaacaat acacaccagt agctgggtac tcaacgacta
     1741 aaaattaatt tggatcaatc tgttcgcttc tcaacatttc tcttatctga aacaaatgct
     1801 ctttttccaa acaatcggga agttgttcga ttcgttcttt ttttagtgat ccttctatga
     1861 ctttccattg attcaaatat cgtttcattt ctcttcctcc tactgtcttt cttgttccat
     1921 ttgaattctt cgttgttgct cttcgtatgc tttacttgcg tggtattttt cttcatgggc
     1981 attaatcgtt cgatttaatt gacgcaaact ccgctgcgtg acaactcttt gttggaattg
     2041 tttcctgcgc ttcatgaatt cttcgtaact atatttgtat tcattcgttg gcaattgttt
     2101 aagcgttcga aaggatcgtt cattgtaaat agattgcatc tgatcaacac tttctattaa
     2161 tggttttatt tgactatcct gtctcttcag ctctgttagg atggcatttc ctgtgcgctt
     2221 ttttaaatca aagagagcat ttttctctgc atcctttgat tctctcttgc tttccccata
     2281 aagatttttt gcttcttctt tcaatgcttt tgaaatctgt atatattctt ggtattcagg
     2341 ttcttttgtt aacacatatt gggttaactc gtcgagtttc tctcttgtgt atggtgaaag
     2401 tttggttcga ttttcatccc cataattcca ttccgaacgt ttttcaggta agtttctata
     2461 tacttcattt aataagttca ttgcgtgtcg atcataacgt actggctctt ttaccacttt
     2521 tgttaagctg ttacgcaaat cactttttcg tgtcaataaa tttcgtttct ccataccaat
     2581 cattcgatcc ttttcataag agaaacgttc taactcatgc acataattgg ttttcattgc
     2641 gtctaatgtt gcttgccttc tctttccttt cggtacaaca taactcacac cattttcaac
     2701 ctcagtgtaa ggtttacgcg tattttcttt ttcaacaact gcaaaatgaa tatggatatg
     2761 tttagtgtta cggtgaatcg ttgccatcca gtagcctgtt tcgttcagtt gctctttctc
     2821 gaataatgtc tccatcattt ttcttccagc tgcttttaac ccttcttcat ctaaagtatc
     2881 tgttttggga tcgtacaatc ctattttttc aagatacgaa ttatcatgag agacaacatc
     2941 ttgataaatg attgagcctt tttgttgtcc tctttggaag atttgcttaa tctccttcag
     3001 atcacttcct ttcacttcgt ctgaagccat agaaaaaact ccaggaaggt ttcctgaagc
     3061 ttttttgtgt ggctctgttt gatatttttt tattgcttgg ttcaagcgtt ggtattcttt
     3121 ttgttccctt tgcgtcagtt ctttcttttg ttctaacgca tagtgacggg tcatataaga
     3181 aagatatttg gtaaaatctt gttcctctaa cttgtcaaag ttgattccat ttcccatcaa
     3241 agattgagct tcattcgacg tttcgctgaa ttcttgatcc gtcttactct ccgaaaaagt
     3301 ttctccttca ggaatataaa aatcatctaa agcattcttg attcgttgca gttcctgttc
     3361 ttcttcaggc gtacgtcgtt ccatttcttc cagcgctttt tctcttgtca tataatcaat
     3421 gtatgttgaa aaagattttt tattgggcaa ggtaaattga caagtgagaa tgactgcagg
     3481 cgatttattc atcatgttcc ccttctactt tttatctttt taaaaacttt gttggatcaa
     3541 acgggtctac tctggcatga acagattcat ttattgattt cttgatttta ggagaatact
     3601 tcttcgtttg attcgctttt attttccctt ccacacgctc ttttgcttct tggtaaacag
     3661 ttgaatttgt accaattaaa atccctgtat ctttcaaatg aagatccgca aactctgaaa
     3721 ccatctcggt taaaatagaa atttcttttc ccattgcatt caatttaatt tgaattggat
     3781 ttattttttc ttcgattttt ggatcataca tcatacacaa atgtctgact gcttcactat
     3841 aattagatat atcttcatga gtagaaatta tttcatcaag tacttcgata tgcatatcgt
     3901 aaagatatac atgttttctt gttgcttttg ccaaaattga tttcctcctt ttataaattc
     3961 acaatactat ttttattatt caattaacaa accaattaat
//
LOCUS       DADVXB010000177         3961 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.183, whole genome shotgun sequence.
ACCESSION   DADVXB010000177 DADVXB010000000
VERSION     DADVXB010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.183"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(33..389)
                     /locus_tag="KB902_002578"
     CDS             complement(33..389)
                     /locus_tag="KB902_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809348.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKIKGFDELGIYIEETKIGYDEIR
                     NVCLYSHIKWQSSKEF"
     gene            complement(382..1707)
                     /locus_tag="KB902_002579"
     CDS             complement(382..1707)
                     /locus_tag="KB902_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6809349.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            2157..2771
                     /locus_tag="KB902_002580"
     CDS             2157..2771
                     /locus_tag="KB902_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809350.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2936..3760)
                     /locus_tag="KB902_002581"
     CDS             complement(2936..3760)
                     /locus_tag="KB902_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809351.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3784..3939)
                     /locus_tag="KB902_002582"
     CDS             complement(3784..3939)
                     /locus_tag="KB902_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809352.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
BASE COUNT         1214 a          750 c          589 g         1408 t
ORIGIN      
        1 gctttcctta ttgtgtaatc ataatattag ttctaaaatt ctttgctaga ttgccacttt
       61 atatgactgt ataagcaaac attacgaatc tcatcgtagc cgatttttgt ttcttctata
      121 tatattccta attcgtcgaa acctttaatc ttgccaatga tatcttctgg atagtatcct
      181 tcagcgtttc gttcttcttt ttgaatagat actgatctat tttttatgac tgcagcgttc
      241 aatacttccg caatctcttc agtcgtcatt tgttcttttg ctaaattttg actggttcgt
      301 tgttcattgt cggcatcaat ttcttcagta tgatcagata aataaaaccc tgcccacttt
      361 aaacgtccac gatcattgta atcaatcatt tttaattccc ccatttccgc ccgcatgacc
      421 accaacaagt gtgcttctag taatgcttct agcgccttct aacattgaag aagcatgtac
      481 aatcgacgta aaaccatatt tttgccgaat cttgtcaata attttatcta aattttcttc
      541 gtcaatttgc ttttgtggat cactaaataa atccagctga agcgaatcgg tgtacacaag
      601 cttgctatag gttattccaa catgccttac ttcttgtcct tcataatact tatcaaacaa
      661 gaaaagacaa taattctgca attcctttgt attatctgtg atagggatct tcatctggtg
      721 tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg tgtaaatgga cacaacctgt
      781 tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc gccatttctt ttaccaccag
      841 ctcgatttca tttcttctag tataatctcg tggtaacact tgtgaatttc catatgattt
      901 ttcctttgtc ggttctggtg ggattgctat atctgttcga tcgatcccat tagcatggaa
      961 gtacagctgt aagccaatca cacctagtct attcttaatc gtataaggat tccagttagc
     1021 aagatctcta atgctcataa tccccatctg attgagtctt tttttcattc gagagccaat
     1081 tccccaaaag tccgtcattt caggaatatt ccatactttt tcaggaacgt tttcgtacgt
     1141 ccattccgca acaaatcctt cattatgctt tgcttcgttg tctaaggcta gtttagccaa
     1201 aaggggatta tctccgacac ctactgtagc aatcaatcct agctcttctt taatattctc
     1261 ctggatcatt tgagccagct tctttctccg ttgacttcgt gttccttcag tcgtaaaaag
     1321 attcagtgat cgggtcactt ttaagattga ttcatcgatc gagtaaatca gtagatcttc
     1381 atcagccaca tatcttctga aaatattatt tacctgcata tttcgcttga tatataggtt
     1441 catacgtggt ggaacaacgt gtagtgtttt aggaaatggt tgtggtaagt cacgtggtct
     1501 actcacattt gtaataccat accgcttttt tgcttcagga gaagaagcta atatcaatcc
     1561 tgaaccagta ttatcagctc gactcataac aacaagttct gttgttaatg gatctaaatt
     1621 tctttctata cattcgacac ttgcgtaaaa gcttttcata tcgattaaaa agtaatcatt
     1681 tactggctct tttgaataat ccatcataaa taacactcca ttctttcaca ttatacaaac
     1741 atatgttcga tattgtaaag aagaaatagc taaatacata aaaaaagaag cataggtatg
     1801 ctatcaccct gcttcttctt ttgatttgta tgatcaattt attctatcac tttactaatt
     1861 aatttgaaaa tctaataaaa actctcactc taaaagagtg agagactgca aattagagta
     1921 cggacttttt tggagttccg ttctttaata ttaacaaatg aataaaatcc ttacaacatt
     1981 tgagaataag ttatcagtag acacttacaa aaaattctca tactatttcc tccatcatta
     2041 gtttttgtct atataaggtt taccctaaat agacactggt ataacattga aaaatatggc
     2101 ttcctcgtgt atgattaggg tgtattttaa atagttgcag aaagtaggta aaagttttga
     2161 gagttgcata catacgtgtc tcatcgatcg atcaaaatga acaacgccag attgaagaaa
     2221 tgaaaaaatt cggtgcagag agaattttca tcgagaaaca atctggcgca acgattactc
     2281 atcgacctgt tttccaagaa gcattagatt acgtccgaga tcaagatatt tttattgtgg
     2341 aagctattga tcgacttgga agaaattatg acgagatcat cgcttcagtc aattacttga
     2401 agaagaaaaa tgtgaagctg atcattacta gtttaccgat catggctgaa gcaattggca
     2461 atcctctcct ggataaattc attaaggatc tgatcatcca aattttggcc atgatcgctg
     2521 aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg aattaagatc gcaaaagcaa
     2581 acggcgtcta caaagggcgg cccaaattat acagtgcaga cgcaaaagat ccccaacgtc
     2641 gccttgttta caaaagcatc gttgaagatc ttaaaaatgg tgttgcgatt gctaagattg
     2701 ctaaagacta caatgttacg agacaaaccg tgtatagaat aaaaaaagac agcatggtca
     2761 atgacaaata gttgatcatg ctgcttttat tatcttctca tctttaattt cctacatata
     2821 attactatct ataaaattaa gtcttactca gaacagataa agcataaaat tccaacaaac
     2881 cattttttac ttaactaaat aaagagtctg ttaatataat cttcacttat ttacgttaat
     2941 cccctactgt atttgttggt tccttatcta tattttctac aaaatcctta ttatcttgtg
     3001 atttagcttc gtataattct ttgtatgtcg acacattggt tatactaatt cctatagcta
     3061 gttcttgaga ctctactttt ctctctagct cctttgacaa agtgatttga gatttatttg
     3121 gttccgttgg agtcaattct atagattctt cataaaaatc tctatacata aagctatcat
     3181 taattttata aaaaaaatta aatgttttta gcactgccat ataacattca aaacattctt
     3241 ctatagttgg tttacttcct tgaggagaat gaaccaattt attacgtttt tctatgaaat
     3301 ttttaatttc ctttcttatt tctttcggaa actcaatatt aaagtaccct ttaaacatgc
     3361 tccctaataa tttgtctaca gggggagatt gtaaattctc aaatattaga gttaaatcag
     3421 gtttctcttg ttgataaaat tcctttaccc ctatttcaca ggctgtaatt atcgaaataa
     3481 acctatctct agtatttgat atatttttac ttcttttaag gagtataaga gaaaagggga
     3541 tactttcgtg tccatgcatg taattaacta attgttgagc ttcagaagtt atatctctaa
     3601 ttatatagtt aacggaatta ggaagtgtct ttaactctaa tgaaatttct atccaattac
     3661 tatcttctaa tctgtatatg ctcgaagtat aatttgattc gtcagcaagc atcgctacat
     3721 cccaaacact gatcataaaa tcttttaaac gttcaatcat ttcagcaata ttgctaaaat
     3781 cagctaattt ttctttagaa taaaaaaaac atttatatca gaatcaataa attctatttt
     3841 ttttattact atatcgtcat cattatcttg accatttatg tttattgttc cctgagtggg
     3901 gagtacttct ttcaaattca agttaaattt atattccatt acttctcctc caatatataa
     3961 a
//
LOCUS       DADVXB010000178         3961 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.184, whole genome shotgun sequence.
ACCESSION   DADVXB010000178 DADVXB010000000
VERSION     DADVXB010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.184"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(241..390)
                     /locus_tag="KB902_002583"
     CDS             complement(241..390)
                     /locus_tag="KB902_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809353.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            852..1064
                     /locus_tag="KB902_002584"
     CDS             852..1064
                     /locus_tag="KB902_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809354.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1342..3141)
                     /locus_tag="KB902_002585"
     CDS             complement(1342..3141)
                     /locus_tag="KB902_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6809355.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3265..3861)
                     /locus_tag="KB902_002586"
     CDS             complement(3265..3861)
                     /locus_tag="KB902_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6809356.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1418 a          702 c          682 g         1159 t
ORIGIN      
        1 tattaaatat tatacagata ataacggaat attatcatcg aaacagctaa caaaattgtc
       61 ataaaaaacg agatggttga tattagaact tgtgtttttg tttaggtcta gagataaaga
      121 gagacaattt ccaaatatat gtaatgaata caaaaagacg tttgtcgcgg attaccgtta
      181 caaacgtctt ttattgattt tccgagatct catcagtcgc catttggaat ggttcactcc
      241 ttatctagat tcgtttaatg ctcggactgc ttgttcgatt gtaataccaa acgcaacgtt
      301 attttcgttt tgtgcatcaa tcgccataaa acggttagaa gttgtatcaa aagctacgcg
      361 gtattgcata tttgtttttg taaacgtcat aaaattcatc tcctttgtaa tgtaatttag
      421 ttcttgaaag tttcctttaa actttcgaac ttataccaag tttagcatcg tacgtttttt
      481 gatgcaatta aaaagcattt atcattttcc ttatttattt tttcttaaat ggtttagcta
      541 ttttctttta atccgataag tagcccaatc atcaaggtta caaatactat tgcttgaata
      601 taaatcatat gctcacctct ttataaataa cttagcaata taaagaaaaa aacgcacgaa
      661 caacatagga atataaacaa acgtttttgt cacaacgtct aagatcgtgt taaaaaatag
      721 ttatctaaaa agcagaaaga tactcaaaat aaaaaataaa aaaatggata aaaacgtttt
      781 caaatacaag gtaatttgtt attataaaat aaagaaaaaa caaaataaaa ataaagaaaa
      841 gagggaatga aatggtaaaa gcagaagtag gaagatctta tatatgcaaa ccgatcggag
      901 tatctcatga actaatcggc tgtattgaac gtacatatat caacacggct gtcgtgtatg
      961 ttgaaagtta tgaccaacga gactatcaac ttatcaatga aagcaagtat cgcatgctcg
     1021 taaaattctg tgatattagc gcacctgctg aattggtttc ttaaacagta tttttgagaa
     1081 ttcgcaagaa ctcccttata atataaataa agacagaagg gagcgagaag atatgccaaa
     1141 aagaaaaagt tcagggaaaa tgggaattat tcttgcagtg atctctgcaa ttcctgctat
     1201 tttagctatt gttcgtgcga tgaaggaatc aagagaaagt taagcacaca ttatgagcgt
     1261 caaacaaaaa acgcatatac ctgcggtggc aggttatgcg ttttttgttg tataaagact
     1321 tttttcatta acgatttttg attagccgac tcccaaaaca aaatttagca gtttatctga
     1381 ataagtgatt tcttcatctg tttgtttcac actttcattt agtagtccca tctcatcggt
     1441 tatgatacca tccacaccat aaaacatcat gcgactcata gcatctgaat cgttgattgt
     1501 ccatacatat acttcttttc cgtcttggtg ggcagaatta atgaagttac ggttgatcgt
     1561 actatattcc attgtcagaa aatcagcagg cgtcacaggg ggcccaacaa tattgaaagg
     1621 taagatgtag cccacataaa agtttggttc tgcttctttt aaatctgaaa cggtttggta
     1681 cgtcaaactt tgcaaaatat gatggttctc taagataact ttgcggtatt tatggacaaa
     1741 tcgttcgaca aggtcatccg aatctttttt agaggtcttg atctcaataa gtaatttttg
     1801 gtttagctta tgtgcttttt ccaaataaga atcaaaagaa caaacagggg cttgcactcc
     1861 gttttcagta actgtaagat ttgtcaattc tttcaatgta agatcctgtg gtgttccatt
     1921 tacccctgtt aagtgacgaa gatttgcatc atgcatcact acgaaatgac catcttttgt
     1981 ttcctgaaca tccatctcta cataatcagg atgatagtct ctgcttgttt tttcaagtgc
     2041 ttctaaagta ttttgcgccc cattttgggt actcacacct ctgtgagaga cagtcactgg
     2101 ttttgtctga acagctgaag tcagataatc catattgtaa agacagacgc caataccgaa
     2161 aaaaactgca aaaagagtca aaccagtgtt tttcagcgca gagaaacgca agttgggggc
     2221 ttgtgggata aaccacttag ggatctcagg caagaagcct tcgtcatcca tgaaatcaac
     2281 aatgatataa aaaatcccta cggtagacat cacgatattg aataataaaa tcccttgtaa
     2341 aagcgtcata gcaaacacag cgctgatcaa tgcatagtct gggaaaaatt gttcaaccat
     2401 actttgtgcc aaaataacaa cgatatatcc taaagaagaa aggagtaaaa tcgtaccgcc
     2461 aatcacaata aattggcccg tgatggccaa aagacgcgat ttggtcaatg accagctttc
     2521 ccgaatggct gctcgaaaag gacgatcccg tagaatcatt tccggtaaag caaaaatcag
     2581 tcgaatccca atatagccaa ggaaaatata aacgagtaaa aaggaactga cgatgatcca
     2641 acgattagca aaaataaaat ccataatgaa agcggggatt tttatttttg acagtagatc
     2701 agaattaaaa cttaatccgc tgatcggtag aatcaataaa aaataagcaa ggaaaaacaa
     2761 aaaagtaatg ggtctcactt tcttcagctg aagtatcgtc aagtgtaaga gttgcttcaa
     2821 agagattggt tctttctttt taataaaaaa aacactcatc aaaagaaaag taaattcgaa
     2881 ataaactaac agtaaaatcg tcatcaaaac tacgattaac gagagtagaa ccccaggatg
     2941 ttgagaaaaa attgaaggaa tattgtcata agacaaatag tcaattgccc ctcggtgtaa
     3001 aataaaacgg gtcgtactgc tcaataaggg taaacaaata aataaaataa agccatgcat
     3061 cagcaagaca tcacggaaat aagcttgtgt tccttttaaa aagtcccaag cattacctaa
     3121 gctacgtttc aaataattca tcctatcacc tgctcttcac attatagcgc aaatctaatg
     3181 aaaaaggaaa gggtgcagtg tgttttgcag accctttccc agatttaaca ttgtcaatca
     3241 atgactaatt ttacaaaata aatattatcc aagaagacca cttagatatt gacctccata
     3301 aatcaaggcc atactatata agaaaatcga cagtggttta gcaatcaaaa tgattagtgt
     3361 atatcgtttc actgacatgt ttgtcaatcc agccatcaaa cataacgcat cgtcaggagc
     3421 aactggaaga aaaatagcta gagcaaacag cttctcaaaa cggttttgat tatccagcca
     3481 gccaatatat ttgttatatg tcttatcgct aatcatggaa agtatgaatg gctttccata
     3541 acgacgccct agcagaaaaa tgataatcga accaatgcag attccaatat agttatagat
     3601 aaatccagca taagggccaa atatcaggac accagctgca gtactgatcc ctccaggaat
     3661 gattggaata actacttgca ggatttggat gaagacaaaa ataatcggtc ctaaaatgat
     3721 ggaatcacct actaatcctc ttaacgcatt caaatctttg aaaacaccta aattaataaa
     3781 ataaatcgtc agcgcgattg ataggcctaa tccgataatg gatatgaaat ttatcagttt
     3841 tcgagaggca gcaatattca ttattcatca actccttaga ggttctttgt taactatact
     3901 ttactagaaa agcaactaac tgcgccattt tttgatatga cagaaaacaa acaattttgt
     3961 a
//
LOCUS       DADVXB010000179         3948 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.185, whole genome shotgun sequence.
ACCESSION   DADVXB010000179 DADVXB010000000
VERSION     DADVXB010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.185"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..419)
                     /locus_tag="KB902_002587"
     CDS             complement(<1..419)
                     /locus_tag="KB902_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6809357.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVIL"
     gene            complement(739..1176)
                     /locus_tag="KB902_002588"
     CDS             complement(739..1176)
                     /locus_tag="KB902_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809358.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            complement(1189..2043)
                     /locus_tag="KB902_002589"
     CDS             complement(1189..2043)
                     /locus_tag="KB902_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6809359.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            complement(2123..2329)
                     /locus_tag="KB902_002590"
     CDS             complement(2123..2329)
                     /locus_tag="KB902_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809360.1"
                     /translation="MIENRVLGFVECKDNLDDTLEVLESIIFNTKVLDLKAINGDMTT
                     HIILDEISAKEIGETLIAWANKEL"
     gene            complement(2711..2935)
                     /locus_tag="KB902_002591"
     CDS             complement(2711..2935)
                     /locus_tag="KB902_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809361.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            complement(3047..3646)
                     /locus_tag="KB902_002592"
     CDS             complement(3047..3646)
                     /locus_tag="KB902_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="HBB6809362.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
BASE COUNT         1313 a          717 c          442 g         1476 t
ORIGIN      
        1 agtattacaa ttaaattgta aaaacaatga atagtaaccg gaacaatcag ccttttatct
       61 gaattatcat agacaaaaga caaaattaaa ctcgtcataa aataaggaat aaaatataaa
      121 tttaagtggg atagactaaa caaaattgca acaattatat atatgcttct tgtagacaaa
      181 tttgttttta attccaattg gttttggata attcctctca ttaaggtttc ttcaaagaaa
      241 ggagcaaaaa tcccacttat gaaaaacgaa ataaacgtta ctaattcagt tacattgtct
      301 tttctttgat taacaaagac caacgctatc atcgaaagga ataaatttac tacaagaaga
      361 actaatgtat agcctattat ccttttccaa taaattttaa tatcttctaa aatctgcata
      421 attagttaat ctgcataatg atataaatag ctgtcgctat taaaattagg tacgaccact
      481 ttccaagcaa agaatataca ggcgaccaga aaaaagagag tactttaaac ataaaccaga
      541 ttatcaatat atagccaaaa aaactccaaa aattagggac aaaccaattg ataaatacta
      601 aagcattagg aattatagcc catttaacca atgcaataat tccacctacc agtagaaaaa
      661 cggctactac atacttccaa atataatttt ctttgtatga ataatttgat ttatgatcca
      721 tagtcttacc tcatttcatt atgcttttcc ttttctttta tcaagatacc atgtcaaagc
      781 tgaagcaata atattagtat tagattgatc tgtttcaaat tttataactt tcaaaacttt
      841 aaaggcttct tcagaaattt ttactggtct cgttttcaac ttgccaaaat cagtaactat
      901 actatttcca tgtgtttcaa attcttttaa aaataaagct aaaatttctg tcattaatga
      961 atatttagcc ccgtatgata aatctttaac aacttcatcg tataattcaa ctggtaccct
     1021 aacagatttc cgtttatcac cagtagactt aatgccagct ttacctttta acatttgttg
     1081 tcctatatta aatccaccac taccgctttt tattccgaac ggattacccg aaccattact
     1141 gccggcacta gttacttttt tagttttcga catcatgcaa cacctttcct aaacacgttc
     1201 taaaatattt tctcctgtag ctttttctaa acgtactaac gtttcttcta caatgtctac
     1261 atacatgcta taagcagttt tagaatgtgg gatagattta tttagtcctt ctctacccca
     1321 acgtttaatt acgcctcgtt ctgaaacaat atgagaataa actaagtctc catattcttc
     1381 ttgaagttct gataaaagtt ctaatcctgt ttttaattta gtatccacta gatatggaac
     1441 aatacctaaa atttctaaat ctccgtttac ttcttttaca gcagtttgat aattagtaac
     1501 cgtactatgc aagttgtcta tagaatcttg ctcagtttgc gtgggaatta ctaaaaaatc
     1561 actcgccacg taaacgttat ctgtaaattc tgaaactgta ggaatagtgt caaacaaaat
     1621 aaaatcatat tgatctctta aattatcatt accgatcata taattaaaca aattccaaaa
     1681 gacttcttca ccttcatcag taaaaccagt acttctccac atatctctta atactttggt
     1741 aaaccttgac atttgttctg aaccaagcac aatatctaag ttttctttaa caggagaaat
     1801 gcagtctaag aaagacatat taattactgc ttcaaacaat gtcattttcc caacaacttt
     1861 taaatcatat tgtctttgaa actttttagt tactgttcct tgtggatcaa catcaataac
     1921 taaaacttta aagcctctag ccgatagaat atcagccatt agctgagtaa gagttgactt
     1981 accaactccc cctttaaaca tgttgattgc aattacatat cccaaaaaat ttgatttcat
     2041 catgtatacc tcacttttga taatttatta tactatacag actacttgta gtcaattggc
     2101 cactttattt taaaattatc ttttacagct ctttattagc ccatgctatt aaagtttcgc
     2161 caatctcttt tgcgctaatt tcatctaata tgatatgtgt tgtcatatca ccattaattg
     2221 ctttcaaatc cagaactttg gtgttaaata taatactttc aaggacttct aaagtatcgt
     2281 ctaaattatc tttacactct acgaacccca gtactctatt ctctatcaac tttagctcct
     2341 ccttataatc agataacaaa aaaattctct aaaagtccta caaaaaaatc tagtaaaaaa
     2401 ggtcaaaagt gaacgattca ttaatataat tcgttatttt ccattatgag cggttttgta
     2461 ataatttcaa tatttttttc tacgcttgaa caatacatag atattaagaa aatatttagt
     2521 gaaatttatc aacgctcatt taataaatcg ttcctcaaaa tattcatatt cctcctttct
     2581 ttaggccata atcgtctgtt tttattcccg atccctctat cgactacttg tagtcattag
     2641 acttttagaa aagggatatt tctatcccta aaaccattct acaccattga ctacttgtag
     2701 tcaatggtta ttattcatca ttttgaccgt tatttttccg atcttctaac catttttcca
     2761 acaattcaat atcttcatct tcagacattt caatgaattt tttagcaaat gatttggctc
     2821 ttatataggc aatagtttcc tgattttttt caacccattt tttcctagcc tttttcattg
     2881 cttcttttct ttcttcttct gtattgtatt ttctcggtct cgccatagaa atcatccttt
     2941 aagttttatc ttctacagta taataacatt taaatacata ttcgattaaa attcaatgta
     3001 tcataatatc caatagaata ataaaataag ataggtttag cctatcttac tctacatcta
     3061 tactttgagt ttgtacatga atatttcttt gggattctgc tatactaaca gcttccaatg
     3121 attctacatt cgtcattatt ttttgataag taattacttc tttacgattt ttcttaaagt
     3181 aactaggatc aagtttacct aacttagaat tataaagtaa ttcgcatgat tcatttattt
     3241 cagactcatg taatttcaaa tattttgcct gtttgattac taacatctta tacttctcat
     3301 caacatttgg gctattaggt gtccatactt ttgcacaatc ttttggcaca ggaatcatat
     3361 tatttatatg aagtactcct aaaaagtcct tttcttctcg atcaccataa atcttaaaca
     3421 ctgatttatt agtcaaagaa cgttgatttt cttttgctga agccaatggt acataataat
     3481 ttatttcttc atttttgtta gaaattttca agtttgattt aaaatataat cgttgttctc
     3541 gatagttgtt ttggacacga tagtccacct ttttcagctt atttatataa tcatctgaaa
     3601 ttacatatag tgtagatttg tttgagtttg tattctttag attcattgga tctccccctt
     3661 tccaatggat tatatatgct aagattaaca gcctataatc ttttttaaaa ctaattgctc
     3721 tcattttaca tttaattcat aaaaatatat tcacgtttat gtaattttat tggtaaaaca
     3781 cactatacat atcaaaacgg tattattcta cttccaattt aacaaaatag caatctaatt
     3841 tgtttgtatt ttttcaactg tcctctaact agttttgtat ttatccttaa ttcagtatac
     3901 ctatattttg ggcacttttg aataaaaata agcggaaaaa caaatgat
//
LOCUS       DADVXB010000180         3862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.186, whole genome shotgun sequence.
ACCESSION   DADVXB010000180 DADVXB010000000
VERSION     DADVXB010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.186"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(70..1371)
                     /locus_tag="KB902_002593"
     CDS             complement(70..1371)
                     /locus_tag="KB902_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6809363.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1748..3370)
                     /locus_tag="KB902_002594"
     CDS             complement(1748..3370)
                     /locus_tag="KB902_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBB6809364.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     PFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFT
                     KEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVK
                     GEREKQFAYSVHTSCDDNGFILSTIITPRNIHDSQVAFQLVKQSKRLFPEINCVVADA
                     GYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDEYFDCYICPQDQMLAFST
                     VTREGYREYKSNPKECVNCPLLNQCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNKS
                     IYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKE
                     PLFFCSKIRNEVDKKLFQARVTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNIN
                     VYFTKARFKRLIAITVSSIVMFLWLFRMGVIP"
BASE COUNT         1159 a          706 c          747 g         1250 t
ORIGIN      
        1 aatggctctt tgtcaaatag gactgataga gtgagataag aacatctaag gtagaattcc
       61 ttttctactt tagatgtttt ttgattcata ggtaatcaga ttatttagta agaaaattct
      121 ggtcttcatt ttccgaaagc ttcgaaagcc ataagcgact cgtttcaatg ctttgatgtg
      181 ggtatgcaga ttttctattt tggcatttga ataaggcaat tcgagggcta aacgaatgcc
      241 ggattcatag tttataaaag ctttttttat agaatgcagt tcttttggaa cggaattggg
      301 catcgttctt acaagtttaa agaaagtgtc cgcctctttg tcgtgaaacg cttgaagaat
      361 ttcttgatag taaaaatagg cgattcgtaa ttcgtcagag atcgaaagca gacgatccac
      421 cacttcactt tcggtgagat acgcccaacc aaaattgcgc catttggtcc atttgtcata
      481 aacaagcttg tcctgtcgtt tgatcagaag ccgagacaac gcctttaatt gtcgataata
      541 tttggcttgt gttggatcgt ttcgatcaaa gcttttcatg attcgtacgc gaatatcctc
      601 aaatttacga atgagatgtt tgacaatgtg aaaacgatcc acaacgagtt ttgcctttgg
      661 aaaacattcc tttatcagag aggcataaga aacattcatg tccgtcacga tgacctttac
      721 cttcaatcgt gcgcgtcgtt caaattgcat aaaataagaa acgagagcct ttttcttccg
      781 tgaaggaaga atatccagta attttccagt atcgccatcc atacaagaaa aggagtaggg
      841 accgacttga tttttcagtg aacgaaattc atccattaat aaacaacgcg gtaaccaatt
      901 tctttttact tttgtcatgg ggatcagaga agcgagtgtc cgagaaacgg tcgaccaaga
      961 aacgccgcaa tgcttagcaa ttgtcgtcat tgcttgtttt tcagttagct cttctaaaat
     1021 tttatagcgc acttgtttag cgataaagca gtttctatcg acaatgtagg tattcgccgt
     1081 aaaataggtg tggcagccac gacagtggta gcgttgtttc gctaaagcaa gataagtcag
     1141 ttggttcgca catttattaa gttgaatgag cgattttttc tttccgttct taacgatcat
     1201 gccttcatga ttcatctgtt tacacaaagg acagcgacga atttctttac ttaacgtcgc
     1261 agaaacaaca agactcttga tattcttaat gctcttcgat tccacatttg tgatgaaaat
     1321 gtttttatct ttgattccaa gtagtagttt gatatgatga agatcaggca tacagaacgc
     1381 tcctttgatt gtgttgtggt gattcaattc taacggagct tctgtatgtt ttgttttttc
     1441 atgctcaaaa gggaccgata gaatgatttt ctatcagtcc tagaaattat agagcctgta
     1501 atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg gtttttattt
     1561 ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa atcctgatgc
     1621 tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag aggatatgca
     1681 agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag gagaattgaa
     1741 taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca atcgacgaaa
     1801 cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg atgttcccag
     1861 agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag atgtctccga
     1921 catcgcagac tgtagacaaa agctgttcca aactcgtaac tcgagcttgg aacagctttt
     1981 tatctacttc gtttcgaatt tttgaacaaa aaaataaagg ctccttgcct ttccatagcc
     2041 aggtggctaa tttctttaaa ttcattgcag caaacactag catcgtatgc gtcgcgactt
     2101 tttccaagcc tcgatacttg gtccaacgca tcccatgctt ttcttttgca tccgcaaata
     2161 ttcgttcaat cgtttgtttc cgttttttgt aaattgattt attcagatct gttaggcgaa
     2221 gatgttccac ttcatccatc agatctcccc aaacatgtct cgtgatgact cgttgatgat
     2281 ttttacttat ggtacattgg tttagcagag gacagttcac acattctttt ggattggatt
     2341 tgtattctcg gtacccttct cgagtaaccg ttgaaaaagc gagcatttga tcttgcggac
     2401 aaatataaca atcaaaatac tcgtcataga gaaactcatt ttttgataat agctcctttt
     2461 tccctttggg ccttgaataa ggcaaacaag gtcgaaggtt caaatgagtc aaaaagtgaa
     2521 caaacttagg tgtcttatac ccagcatcag cgacaacaca attgatttca ggaaaaagtc
     2581 tcttcgattg tttgacgagc tgaaaggcga cttgactgtc atgaatattt ctaggagtga
     2641 tgattgtgct aagaataaat ccattgtcgt cgcatgaagt atggacagaa taagcaaatt
     2701 gtttttctcg ttcgcctttg acgtagtagc cgctttccgg atcagcttta cttatttttc
     2761 tttctttcag cttcacttcc ttttctaagt ccaaagtaaa agggcgtttt ccagcctcta
     2821 ttcgttgacg attgatctca tcttctaatt catcctgata ggctttcgct tcatcatggg
     2881 tcatttcttt cgtaaactta tgtttattgg cgttagcttt gatgtgggta gaatccagat
     2941 acaaattatc ctctgttaca aaacctgctt taactgcttg ttctaaaata taggcaaaaa
     3001 tatcctcaaa caccgtcgtt tctctaaatc ggcgaacata attctttcca aaagttgaga
     3061 aaggggggat tttctcctcg aaggagtagc ctaaaaacca gcggtaagcg acattggtat
     3121 cgacttcctt aatggtttgt cgcatggaac ggataccgaa taaatactga ataaacacca
     3181 atttgatcag aatcactgga tcgatacttg ggcgacctaa atcggagtaa gtggcttcga
     3241 cgattggata aataaattca aaatcaagcg cggcatcaat ctttcgaacg agatgatctt
     3301 gaggaactag atcatcaatc gtaagcatcg caaattgatt tctaccattc gtattgtttt
     3361 tagacatcat agctatcact ccttgcattc gttttcataa atctattata aaagaaaaga
     3421 ctgtagacat catccataaa atggactttg tctacagtct ggataacgtg attttttgct
     3481 gtaatgacaa ggttttagct gtttcagata ccatgtatcc aaaaatagtt tattgagaaa
     3541 ataggagagt atttgatact aactagtagg aaaaaatgag ataaaaagta aatggaatca
     3601 tttaaggtaa tctgaaataa aaaatataca gccctgtggt actttaccta caaggctgta
     3661 tatatttttt actctcagcg tttttgactc cgtgtctgac tccgttttat tgattttgaa
     3721 tgttattcaa tgaccattta acaggtcaaa tttgatgttt ttgattccgt atgacgccgt
     3781 ttgatatcta gtgatatagt gatttgagtc tacatcgaat aagggaataa accaataaaa
     3841 aatgatttag aatattaaaa ta
//
LOCUS       DADVXB010000181         3734 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.187, whole genome shotgun sequence.
ACCESSION   DADVXB010000181 DADVXB010000000
VERSION     DADVXB010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.187"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            102..554
                     /locus_tag="KB902_002595"
     CDS             102..554
                     /locus_tag="KB902_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809365.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            568..1257
                     /locus_tag="KB902_002596"
     CDS             568..1257
                     /locus_tag="KB902_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809366.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1382..3733
                     /locus_tag="KB902_002597"
     CDS             1382..3733
                     /locus_tag="KB902_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBB6809367.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
BASE COUNT         1266 a          490 c          774 g         1204 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc ataaatttaa taagaaagcg aggtgagaat cgtgaaaaaa acgatactaa
      121 gtattttttc agtatttaca atattaattg ggggctattt tcttttgaat ttagattctg
      181 ttaattcaaa cgctcaaata aaagatcaaa gagtagctga acataataat aaaaaaatga
      241 gtttgaccaa aaatatctat tctatgtcag atgaagaatt gtataaagaa tttggtgatt
      301 tatccgggga acagttagaa gaaagtattc caggaattag tgactcagat aaaattgttg
      361 tcttgtctgc tggtgggcaa ttaatgggag atggcaaatc cgaattagtt agttataaac
      421 aaaatcacag acagtttatt gatgttaata ctgattccaa cgctatttcg attaaggatc
      481 taaaagagct tttaaatagt aaaagaaatg aattaaagca gataaaagaa actaattcag
      541 tggaattaga gtaaaggaag attcattatg aaaaagattt ttggtgtttc tgttgggcta
      601 cttatgatgt taacatttgg aaatgcagta tatgctgctg agaaagaagt tatttcagat
      661 ccagagcagt acgcctcacg atactttgct gattttgaag aagaagataa agtacttgca
      721 ttgccagaag gtggtttttt aaaaggggaa gctaaaattg tatctatgga taatccagat
      781 ataattcaag gttcatataa ttcagaaact gatcctgctt cagtttcagt gacagaagca
      841 aaaaaaattg ttgctgaaaa attcaaaaat gatattgaaa ctactccaat tatgcctcga
      901 ggagcatttc cacccgatgt tggtactagc ggacaccttc ttgtactagc aggaggagga
      961 agctataaat cacagccatt tagtggtgcg ggatggcgtt ttggaggtat gggtgtaaaa
     1021 ccagctgatg gtacaggcaa ctttttacgt tggaaatcct acattgacga tggaagagta
     1081 ggaaatgtaa atcaagccaa cgcaactaaa tctggttcta ttcaaggaat ggcattgtat
     1141 gctcgtgaag gattcaaata ctttgcacca aacgggcctg gttggacaat gaatataggt
     1201 atttattaca cttataatcc tgttgcaggt acgtattatg ttgttcaaaa tatttaataa
     1261 aacagcacaa agagatttct ttgtgctgtt ttattatttt tagttgttga caaacactaa
     1321 aatataaaat ataatcaaca cataaacgaa cgtatgttcg gcaagaaagc aggggatttt
     1381 tatggatgag atggttttaa gtactcagaa atggctaaac aagaaataca gtaatgttac
     1441 agggtttgat aaggttccag aaaatgggcg aacagggtgg cctacaatct atggacttat
     1501 tgaaggacta caagtagaac ttggtattac taatctagta gctaattttg gacctaccac
     1561 tgaaaaaatg tacgataatc aggttactcc taaatggggc aaaaatctac ctaaaaatat
     1621 tgtatttctt attcaaggtg ccttttggtg taaggggatt aatccaggtg gcttcgatgg
     1681 ggtatatact ccatatttag atactgctgt aaaagagttg cagactgatg cagggtttaa
     1741 tggaagcgct gtaactggag ttttggatgc gaaatgggcc aaagcgttat ttgatatgag
     1801 tgcttttgtt cttgttcccg gcggagatag taaaattaga aaaatgcagc aatggttaaa
     1861 tgtaaattat ttagaataca cgggaataat gccttgtgat ggtatttatc aaagaaattc
     1921 aaatcaagca ttaatttttg cattacaagc tgaactagga tattctccca gtgaagcaac
     1981 agggtcttat ggtaatggga caactagtaa aacttatcct gtgtctgaag gtaactcggg
     2041 aaactatgta agaataattc aatatggatt atatgttaat ggttattttg aagacggtac
     2101 attcgatggt attttcacta aatatatggg tttagaagta ctggcattcc gaaaatttat
     2161 ggtattgcct gaatatactg aaatagcaga tgttgttgta ataaaaggac ttttgtctag
     2221 cgctggagat attagaagat ctgcagatgg cgcagatact tctacgcaat taactagatc
     2281 tcaaatccaa acattggttg ataatgatat aaaaatagtt ggtagatatc ttactggtac
     2341 tgttggaatt ggaaaagatg aacgaaataa gtatctaact acagaggaat tgaataatat
     2401 tttttctaaa aatttatctg tgtttcctat ctatcaagat ggaggtgcag cattagctta
     2461 ttttacttat gatcgtggct tatcagatgg taagaaggct atagatgcag caaaaaatct
     2521 aaatatacca ttaacaacag ttatttattt tgctgttgat ctagacatgt taggggaaga
     2581 aattcttgca tatgctggag aatattttaa gggggtatct gctgtaatgt catatagcgg
     2641 gtatcaaacg ggtgtttacg gaacaagaaa tgtttgttct caaataatca ataacgggta
     2701 tgcttcgttt gcatttgttt cagatatgtc gactggttat agtgggaatt taggttttcc
     2761 tatgcctaga caatggtctt ttgatcaatt tgttgaattt accataggaa gtggcaacgg
     2821 agctgttggt atcgatttaa tcgctacatc gggtagagat agcggattta atgagttatc
     2881 aaatgatact aataatgata attacattgc caaatacaat cagaaggtta taaatcagat
     2941 ggtacgtgcg tatcaatatc tatcacaagc tggtcttgat aatccttgga accctcattt
     3001 gacattttat agatatgtaa attattctgg tttgtcatgg gacatcattt cttctcctgt
     3061 aacagagcat gatagaaaaa tttatgatga atataggaat aaattaacta atagcgaggg
     3121 cctgtataat tattttatag atcctaatac tggttcaata ataggtttgc ctcacttaat
     3181 tgtgacgtta caatcacaga tgtttctagc cgacacaatc aatgatagtg tttctgactt
     3241 tgcaggttgg ttaggagatt taatgacttg ctggggtgaa gttaagaaat taggaataca
     3301 aatggagcaa ggtgtatttg cattagtagg tacggctgca ggtggaacat ttagtctaga
     3361 agatttatac caagatgttg acgcggtaaa tgtttatacc ttagcaaaaa gaaattctga
     3421 ttcaacagct ttatcggctt taaaaacgta ctattgtgat aagggtgcta ttgatagatt
     3481 taatcaattt gttaagaaca gatttggttc ttcagataaa atcgcttcag taacaaatag
     3541 tttattagaa aatgacgaaa cagttgatat cttaggtgta gggataattt catttttcat
     3601 tgataaaata gttaataatt cacttgggac agattttact tatcttgatt ttattggaga
     3661 tgaggggaaa gttgcaaatg gattttctga aaaaattatt caatttcaag aaaatagaag
     3721 taaacttaat taag
//
LOCUS       DADVXB010000182         3703 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.188, whole genome shotgun sequence.
ACCESSION   DADVXB010000182 DADVXB010000000
VERSION     DADVXB010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.188"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            87..2528
                     /locus_tag="KB902_002598"
     CDS             87..2528
                     /locus_tag="KB902_002598"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBB6809368.1"
                     /translation="MKEVVMIDAARTPIGKYRGGLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2858..3562)
                     /locus_tag="KB902_002599"
     CDS             complement(2858..3562)
                     /locus_tag="KB902_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809369.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         1187 a          654 c          811 g         1051 t
ORIGIN      
        1 aatttaatct tagaaaaaaa taactggaac aagagctatt tgtttttaca gcaaagaatg
       61 gtatattttt gtaggaggtg gcttacttga aagaagtcgt tatgatagat gctgcaagaa
      121 cgccgatagg aaagtatcgc ggaggtttaa gtccatttac tgcagttgaa ttaggcacac
      181 ttgtgactaa aggattatta gataaaacaa aactgaaaaa agataaaatc gatcaagtaa
      241 tatttggaaa tgtcctgcaa gctggtaatg gtcaaaatgt tgccagacag attgctttga
      301 acagcggtct ccctgtagat gtcccagcaa tgacgatcaa tgaagtttgc ggatctggta
      361 tgaaagcagt gatcttagca cgccagctga tccaattagg tgaagcagaa cttgtgatag
      421 ccggcggaac agagagtatg tctcaagcac ctatgctgaa acagtatcag tcagaaacaa
      481 atgaatatgg tgaaccaatt tccagtatgg tcaacgacgg attgactgac gcattttcaa
      541 atgcacatat gggattaacc gcagagaatg ttgcaacaca attttctgtg agcagagaag
      601 agcaggatcg ctatgccttg tcgtcccagt tgaaagcagc acatgctgtc gaagccggtg
      661 tattttctga ggagatcatc ccagtcaaga tttctgatga agacgtgtta tctgaggatg
      721 aagcagttcg tggaaatagt acattggaaa aactgggcac gttacgtaca gtattctcag
      781 aagaaggaac tgtaacagca ggaaatgctt ccccgttgaa tgacggtgcc tctgtggtga
      841 tccttgcatc caaagaatac gcagaaaata ataatctgcc ttatttagca accatcaaag
      901 aagtagcgga ggtcggtatt gacccaagta tcatgggaat cgctccaatc aaagccattc
      961 aaaaattgac agatagatca ggaatgaatt tatcaacaat cgatcttttt gagatcaatg
     1021 aagcatttgc agcttcttct atcgtagtta gccaagaact gcagttagat gaagaaaagg
     1081 tcaatatata tggaggagca atcgcattag gccatccaat tggtgcaagc ggtgcacgta
     1141 tcttgactac attagcttac ggattgcttc gtgaacagaa gagatacggt attgcttcat
     1201 tatgtattgg tggaggttta ggcttggcag tcttgttaga agcgaatatg gagcaaacac
     1261 ataaggatgt gcaaaaaaaa aagttttatc agcttacgcc atctgaacgg cgcagtcaat
     1321 taatagaaaa aaatgtattg acacaagaaa ctgcgttgat ttttcaggaa caaacacttt
     1381 ctgaagagct ctccgatcac atgatcgaaa accaagtgag tgaagtggaa atcccaatgg
     1441 ggatcgcgca gaattttcaa atcaatggca agaaaaaatg gattccgatg gcaacagagg
     1501 aaccatctgt cattgcagct gcaagtaatg gtgcaaaaat ctgtggaaat atctgcgcag
     1561 aaacacctca gcggctgatg cgagggcaaa tcgttctatc aggaaaatcg gagtatcaag
     1621 cagtgatcaa tgcagttaat catcgaaaag aagagctgat tctttgtgca aatgaaagtt
     1681 atccttcaat cgtgaaacgc gggggcggtg ttcaagatat ctctactcgg gaattcatgg
     1741 ggagtttcca tgcatactta tctattgatt ttttagtgga tgtaaaagat gcaatgggcg
     1801 ctaacatgat caactcgatt cttgagagtg tggcaaacaa gttacgggag tggttccctg
     1861 aagaagagat tctattcagt attttaagta attttgctac agaatcattg gcttctgcct
     1921 gttgtgaaat cccattcgaa cgcttaggga gaaacaaaga aatcggtgaa caaattgcca
     1981 aaaaaatcca acaggcaggg gaatatgcga agcttgaccc ttaccgtgca gcaacgcaca
     2041 acaaagggat catgaatggt atagaagctg tagtggcagc tacaggaaat gatacacgtg
     2101 cggttagcgc ttcgatccac gcctacgcgg caagaaatgg attataccaa ggattaacag
     2161 actggcagat caaaggggat aaactagttg gaaaactaac ggtgcctttg gctgttgcca
     2221 cagtaggcgg agcttccaat atcctgccaa aagcaaaagc atctttagct atgttagata
     2281 ttgattcagc caaggaacta gcacaagtaa ttgctgcagt agggttagct caaaacctgg
     2341 ctgctttgcg tgcattagtt acagaaggaa tccaaaaagg ccacatggga cttcaagctc
     2401 gttcattagc gatctcaatt ggggctattg gtgaggaaat cgagcaagtt gcgaaaaaat
     2461 tacgtgaagc agaaaagatg aaccagcaga cagctataca aatattggaa aaaatccggg
     2521 aaaaataaaa aagcaatatc tttagaagaa taaagcaaga tttacagtta ttttatttac
     2581 tgcagatctt gcttttttct ctatcagaaa atatgtttat tattagaatt ttttatagtt
     2641 aaggttaggc atcttaagaa atcaggcaac tccaagatat cttcaggtag aagagaagtc
     2701 gcctaacatt gtaggatcat aggtgatttg ttggacaggt caagctgata tttgagcctg
     2761 atgttagaag gaatttcttt ttacttgctg tagaaattat tatatgacta aaaaggctgg
     2821 gattttaaat cccagccttt tatgacaaat agaattttta tcgatcagta atcgctgtcg
     2881 ctgcaaattg ttcgatcaaa ggaatcaaag tcaatttgac tttgtatttc cgttcgagtg
     2941 ctttttcgat aacgaactca ttttcagtag tcatagaaat agttgctaat ttacgaggtt
     3001 catcagcatt tttttcatta ataactactt catgttcatt ttgttctgtg taaaatttag
     3061 gatactcagc aacggctttt gaaaaatcag caaaacttaa agcggcattc gtatcagttg
     3121 agcgtgtatt ttcagttgtg tccgcttttg gtttttccgt tttttcttct ggcacactga
     3181 ctgtttcttc tgtaactggt gtcgcaacag cttgcgcagt tggttcatcg tttttcaatc
     3241 gttgatcatt ccagtaagac acgatttcaa taagaagatt gtcacggaat cgttcgaaaa
     3301 tcccgttttc tcctgaacga attctcttta atacagtatt gaagttgtca tcgattggca
     3361 cgttgatccg tgtatcttca tttgttttcc cagctaatcc gatcgttaag atttgacggt
     3421 ttttgggatc aagcatgact tgtaacggca aaccataacg tcgcaagctc tcttcttcta
     3481 gagaacggaa taattgtcct cttacaccat ccaatgaagg acggaattga tttaataatt
     3541 tttgtttctg ttttttcttc atatgttctc tccttcgctc ataccctttc gattataaga
     3601 aaaaaacagc caaatgaaaa ggagtaatgc aaaaaaactt gcgtatacgc aaattacaac
     3661 agaaaaattt gcgtattttc ccgttttttg aaagaaaaat aaa
//
LOCUS       DADVXB010000183         3697 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.189, whole genome shotgun sequence.
ACCESSION   DADVXB010000183 DADVXB010000000
VERSION     DADVXB010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.189"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(65..358)
                     /gene="rpmA"
                     /locus_tag="KB902_002600"
     CDS             complement(65..358)
                     /gene="rpmA"
                     /locus_tag="KB902_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBB6809370.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(371..715)
                     /locus_tag="KB902_002601"
     CDS             complement(371..715)
                     /locus_tag="KB902_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBB6809371.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(742..1050)
                     /gene="rplU"
                     /locus_tag="KB902_002602"
     CDS             complement(742..1050)
                     /gene="rplU"
                     /locus_tag="KB902_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBB6809372.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     misc_feature    complement(1070..1146)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            1332..1973
                     /locus_tag="KB902_002603"
     CDS             1332..1973
                     /locus_tag="KB902_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6809373.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(2035..3666)
                     /locus_tag="KB902_002604"
     CDS             complement(2035..3666)
                     /locus_tag="KB902_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBB6809374.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
BASE COUNT         1129 a          821 c          657 g         1090 t
ORIGIN      
        1 tttttataaa caaaaaaggc tgtgacaaaa gtcttgtcac aacctcttta atcataagat
       61 tcaattaagc ttcttgagct actggataaa cagacacttg ttttttgtta cggcctttac
      121 gttcgaaacg tactacgcca tcaacttttg caaataaagt gtcgtctcca ccgataccca
      181 cgtttacacc tggatagatt tttgtaccgc gttgacggta aagaattgat ccacctgtaa
      241 ctgtttgtcc atcagcacgt ttagcaccta gacgttttga ttctgagtca cggccgttag
      301 atgtagaacc gccacctttt ttgtgggcaa ataattgtag attcatagat aacaacatgg
      361 tctgcacctc ctatttatca ttaattgttt taatttggat atattctgag ttttcagctt
      421 ctatcgattg taatcctaat aaaagatttt ctaatagaat ctcagcaata ttgttttgtt
      481 cttgtgtcat tcctgaagtg acttcggtat aaagataacc gccttcttct tcattcattt
      541 caacaatcgg ctcaaaaccg gctaatgagg caatcccgtt gacagtgctg atcgctaacg
      601 cagaaacacc cgcacaaacg atatcacttc cataaggacc agcatcagca tgcccggtca
      661 aagtgaatga aacgatctga cctgcgtcat ttcgcttaaa tgttcctttg atcatatata
      721 ggccttcttt ctcaaacgct attaagcgtt gatcgcgtcg ataaccactt ttgtatatgg
      781 ttgacgatga ccttgtttac ggtgtgaatg ttttttaggt ttgtatttga aagtaacgac
      841 tttcttttgt ttgccgtgtt tttcaacagt accttcaaca gttgcacctg caacagttgg
      901 agcgcctact tttgtagatt ctccgcctac taagataact tcgtcaaaaa caactttttc
      961 tcctgcttca acgtcaagtt tttcaacata gattgcttgt cccacttcaa cttttacttg
     1021 tttaccacca gttttaataa ttgcgtacat gctataaagc acctccttct gatatactta
     1081 gactcgccat ccgaagtgac agcatatgct gtgcttatta cttgttctga gcggttgtag
     1141 ctgtggagtc cacaattaca acagtactag cttaccagaa cagcaaccgt tagtcaacta
     1201 aatttaaaat caaaaagtaa aacaaaaatt caagcaatac ttctgctttt ctatcctcac
     1261 agttctacca aataaaatag tcgcattgtg tttcttttat tcttataata aaagaaaaag
     1321 gaggagcata aatggaatac ccaaaagaac tgatacaaga agcttcttta agaatgaacg
     1381 gccgtcctgt agaaggattt atcgctgggc aaggacctct tcatcctaaa ctgatgctcg
     1441 tgggagaagc cccagggaaa acagagattg atacgcatgt tccttttagc ggtcaagctg
     1501 gaaaagaatt gatgcaggca ctttcttcaa ctggcttaac acgagaagag gtgtatatca
     1561 ccagtgctgt aaggagccgc ccgtatcgcg tgactcatcg gatcaataaa cggacacaac
     1621 agtcagaaac tgtttatcca aatcggacac ctactcgttc cgaagtattt gcgcatgcac
     1681 caatattgga ttacgaactg atgaaggtcc agccaaaatt aattgcgaca cttggaaaca
     1741 ttggtcttca acgtttactt ggcaaagaat atacggttac caaaaatcat ggtcaactct
     1801 atacagggcc tgtcttacaa ttaacagaac aaaaggatgc ctacgaatgg tcagaaaaaa
     1861 actatcgaat tcttccactt tttcatccag cagctatttt ctacaatcgc tcccttgtac
     1921 ctgttatcca tcaagactgg caagtactag cttcactttt acagcaatat taaaaagaac
     1981 agacaagacc ataaaatctt cagtttacag tcttgtctgt tctttttcat tgttttaatg
     2041 gctaattgca gtatatttcg catgtaaagc tgtcaacgca tgagcaactg tttgatgttg
     2101 atgcgtgaat gtatgttccc acaagtgaga aagttgtttt tctacttctg gctgcaagga
     2161 agtatagata atcgtttgtc ctctttgctc tgctttttct tgaaattcat caaaaactgc
     2221 acgtgccgtc aaatcaatac ttggtacgcc tcgcatggag aaaatgacac catcgtgatg
     2281 atttagttct tccaatttat ttttgagttt ttctgaagac ataaaaaaca gtggaccact
     2341 aatatacact actgtccagt tattcagctt ttccgtttct ggcagcccca ttctttgcca
     2401 atcgatcgtt tctaatgaaa tcgtgatagc agcgcttttg acaacaaaaa atacacagcc
     2461 gccgatcacc ccgatcacga tagcaatact taaatcaaag ataactgtac aaatcatcgt
     2521 aaggataaac aatagaactg ctgaccaata tttattagta aatagctcct tgatcgtttc
     2581 ccattcattc atacgccaag ccgtcacaat caaaacacct gcaagtgctg gcattggaat
     2641 ctgtgacatc actggcgcaa aaacaagcat ggagagcagt aagacaactg catgtatcat
     2701 accagctaat ctagtttgtg caccagattt gatggccacg cttgtacggg cgatggccgc
     2761 agtagcagga atcccgccaa agaaaggaag caacagattt ccaattcctt gcgccattaa
     2821 ttcttgattg ctatctaagg gcttatttgc cattcggcca gccgaagcac cacatagcaa
     2881 gctttcaatc attcctaata aagcaatgct aatagctgga actgccactt gttgcaaggc
     2941 agaaaagcta aaatctccca tattcaaacg attactactg atcaatgttt gtggaatctt
     3001 acccacagtt gctactggta aatggaacaa tagcataact gctgttgcca aaatgatagc
     3061 cagcagcgaa ctaggcattc gtttcgccca tttttttgga tagataaaca tccctaaaat
     3121 gactagccct cccatgatca aagaggctgt gtttatcgga aatcctatcg tttgataact
     3181 acttagtttt tcaataacgt ttgtaccttc cgagtgaaca ccaaataaat tatcgatctg
     3241 acctaatgca ataatgatag caatacctga agtaaacccc gtaattacgg gtgctgggat
     3301 aaaagaagtc agtgttccta atcggaaaag tcctgctgca agtaaaaata gacccgctaa
     3361 aaaagtagca agcaatacac cttgcattcc ctttgttgcc gcaatagaca tcaagatagc
     3421 tgccatcgca cctgtcggac ctgatatttg ataaaaaccg cctgataaac cgccaataac
     3481 gataccggca atgatagccg taatcaaacc tgcggccgca tcagctccgc ttgatacccc
     3541 aaaagccaag gctaaaggca atgctacagc agctactgtg atcccagcca aaagatcttt
     3601 ctgaaatctt gaaagatcat aacctgaaaa ttcttttttt agtgaggaaa cataattttt
     3661 gaacacctat ctaactcctt tttcatgaaa ttttcta
//
LOCUS       DADVXB010000184         3635 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.190, whole genome shotgun sequence.
ACCESSION   DADVXB010000184 DADVXB010000000
VERSION     DADVXB010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.190"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            70..885
                     /locus_tag="KB902_002605"
     CDS             70..885
                     /locus_tag="KB902_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809375.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1011..1268
                     /locus_tag="KB902_002606"
     CDS             1011..1268
                     /locus_tag="KB902_002606"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809376.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1520..2092)
                     /locus_tag="KB902_002607"
     CDS             complement(1520..2092)
                     /locus_tag="KB902_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809377.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2108..2713)
                     /locus_tag="KB902_002608"
     CDS             complement(2108..2713)
                     /locus_tag="KB902_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBB6809378.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(3114..>3635)
                     /locus_tag="KB902_002609"
     CDS             complement(3114..>3635)
                     /locus_tag="KB902_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBB6809379.1"
                     /translation="LEEGVEPDKVTSKVINQLKEKGSLKHLGEYEVLDTAMLTKGIGQ
                     ILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRALGATRKSIMLQFLL
                     EGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMPA
                     SEAAKKDLIDILR"
BASE COUNT         1182 a          694 c          549 g         1210 t
ORIGIN      
        1 attaaggtgc tggactacaa gtaaaaaata ctgtatgatc atgacagatt caagaaagga
       61 gcaataagat tggttaagat agcaggactt tctaaaggtg gaaaaaccgt ttcacaactt
      121 tataaacaaa actacagaga ctggagacag ttcagaaaaa acattaagga ttcttacttt
      181 attctaccaa cagaacttga aaaatattta ccgaataaca aagctattaa tttatatctg
      241 tattactgtt ttaaggcaaa gaatgaaggc ggggattcct ggcattcggt caataccata
      301 gcagagtctc taggagtgac aactaaaact ataaacacct ggaataaaac cttagttgat
      361 ttaggtatga ttgcacgtat agacgataac catctcagta aatcgacaat tttacttcct
      421 ctctctagtt actataaatt agcccttgat agttctttaa aggatgttac cgagagcact
      481 gtccatgaaa ttgatggcaa cttggttgca gtttatcatt tgtttgaatg gagaaaaaat
      541 gaggctgatg aaaattataa cgttccttat aacacactct gttgtgtttt taaaagaaaa
      601 acacaaaaag atactatcta taaatttatc ttggtccaag atgagaaaat aagtaatttc
      661 gaattaagca ctccttctag taagatttat gacgatgcat atagatttga atgtcaagat
      721 ctagaagccc tcctttccgc aaataatcta aacaatatag aacatgaaaa ctttgttgta
      781 aacactagat ttaatttagt ttctgaaaag gactcagatt tgttagattt gctgatagag
      841 cttactaaaa atctagataa gaaagaaaac attactgtac tataactagc atcggtccat
      901 cattaagttt ggactattag aacacttgct attacagaaa aaggtatgct agccacgctt
      961 actatttatt ggtatcaaac aagtatctta atttgaaagg aagatgattt atggctaatt
     1021 tatatataga gaacaaagga gacttgaatg ccattattac tttaatcgta gttatggtaa
     1081 aatcaatagg taatatcaca ataggaatgc tgtttattat attagcagca gtgctgattt
     1141 ttatgatagt tatttggttc ttaaatgaaa gatctaaaga caatcaacac cgtagggata
     1201 tggagataaa atcaatagag tcaatagatt atttatcgat aataacacta aaaaagccac
     1261 gttcctaaac gtgacttacg ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc
     1321 attataaata tatgatggta tcctaatata gtaagcgtgg ctagcatacc tttaattact
     1381 ttacctttta cagttaccat acacattttt tgagcagaaa tcaagtaaat aaaaaaatat
     1441 tatatttcac aacatgctaa tagactcata tctagaacgc attaagtatt tacctgtctg
     1501 gttcgctgag acttcttttt taactttctt caattttctt ctttattcta aaaagcgtac
     1561 tgcgactgaa accggttata gcttcaactt ccttatacga tttacctgaa gtaagcagtt
     1621 catatgcgtg cctcttcttc ggtgtgattg ttgctttcgg acgtccttct ctgaaattag
     1681 gattattctt tcttgcaaac atttttcctt cttgggtacg ttccacaatc atatcacgtt
     1741 ccatttctgc tacactcaac aacgtccgtg tcaccattcg ccccatggac gtattttcaa
     1801 tcgttcctag attcaaaacc ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct
     1861 ctaatgcttc tctcgtgtta cgagcaaatc gatcaagctt cgtaacaact atttcatctc
     1921 caggcttcag accagccaac agctgattga attttggccg atcccgtttt gtacccgtaa
     1981 atttttctga aaaaatattc ttcttctcta cgccgttctc aagcaactgt tgaatttgtt
     2041 cttttgtact ttgagaagcg gttgagacac gtgcatatcc atatttcgtc atttggtcca
     2101 cctactttta caaatcatct atcgtatact cagaataccc ttcatagaaa tagctgacat
     2161 cgattccttt catatataac tcgcgatcgt caattttatc agtcagagca ttggaaatta
     2221 gatagcgtat ttccaaatcg tttatgggac ttcgctccat tgcagaaaga tagtctgctt
     2281 tatcgattaa gttccaatct acaacttttt gcaattcttc ctttaaaatg agatccagcc
     2341 aaattctagt acttcggcca tttccttctc gaaatgggtg agcgatattc atctccacat
     2401 atttcttgat aatctcttca aaagaagttt gtggcatctg atcaatatgc tgtaacgaat
     2461 gttctaaata cataactggt gcaaatcgaa aatttccttt tgcaatattg accgatcgga
     2521 tttttccggc aaaatcgtaa atatccgaaa atagaaattc atgaatttca gataaacctt
     2581 taaatgtacc aacttcgatt tcatttattt ttccacaatc gtacaattct ttcgcttttt
     2641 gtttactgag tttttcttca accttagcca actcaacttg attggttaat cccaatttat
     2701 tctctaaaat catgcgaaat ctccttaact ttatgacata agtttatgaa acactctcaa
     2761 ccccattata tcgcgatttt gtttatgtgt caaaaactat taagtttctg acccccgata
     2821 gatttttcaa gtgtctctat tttgcacagt ctagttgacc tttgatacac ctctatattt
     2881 atagagaatc taaaacatca acatggcata ctcaaaattc taaatattag ggataaagaa
     2941 ttctcctata caatcaaaaa tttcctttat ttcgaactcc ggtcacctaa ctctattgat
     3001 ctcttacaag ccaaagaata tctctatact acaaagaaac aatagggtgc ctggttggtc
     3061 tctttgtgtt ttattttaga atctagaacg taaatattct tgtcattctg attttatcta
     3121 agaatatcaa ttaaatcttt ttttgcagcc tctgaagcgg gcattacaga aaagaccagt
     3181 ccaataaccg aagatacccc aaccgctagt aaaatagtaa atagatcaag tgacacgttt
     3241 acctttatca aagaaccaac actataagca agagccattc ctaataaata gccaattaac
     3301 cctcctgaaa gagttaaaat caaaccttct aaaaggaact gcagcataat cgattttcga
     3361 gtagctccta gggctcttct tataccgatc tcttttgttc gttcagatac agatatatac
     3421 atcatgttca ttacacctac ccctgcgata aataaagata tacctgctac agctgttata
     3481 aaataagtga tcgtactgag gatttgacca attcctttcg ttaacatagc cgtatctaac
     3541 acttcatatt cccccaaatg tttcaaacta cctttttctt tcaattggtt tatcacttta
     3601 gaggtcacct tgtcaggttc aactccttcc tctaa
//
LOCUS       DADVXB010000185         3586 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.191, whole genome shotgun sequence.
ACCESSION   DADVXB010000185 DADVXB010000000
VERSION     DADVXB010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.191"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            192..425
                     /locus_tag="KB902_002610"
     CDS             192..425
                     /locus_tag="KB902_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBB6809380.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            422..829
                     /locus_tag="KB902_002611"
     CDS             422..829
                     /locus_tag="KB902_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6809381.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1966..2484)
                     /locus_tag="KB902_002612"
     CDS             complement(1966..2484)
                     /locus_tag="KB902_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBB6809382.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1220 a          602 c          552 g         1212 t
ORIGIN      
        1 aatttaaaat aaatggtata cataaatagg gaaggaaata gaagggagca atctaaattt
       61 tttgaatttt cttaattaat tatatagaaa gaacaatctt tctatagagt tagacatgag
      121 agggactatg cttgatttaa aatcaacaag cgtatatact gtatatacaa agaaaaagga
      181 gggagaagac tatggcaatt aaagaaagaa aatttaggga agtggggaac tcagtagtat
      241 taactatttc aaaggagttt cttaaagaaa atgggttaaa tcccggagat acggtttttt
      301 tagatgaaga aaaacttcga gcggcaatta caaaaaaaca agccttatct gatgaaattg
      361 atttagcaat atctcaagca ttaactgaat atgatactac ttttagagag cttgtcgata
      421 aatgagtatt cattacctag aagccaaaga tattataaaa atgaatgtaa tccaaataaa
      481 aaaatactct cctaatgaac cccttggtgt aaaggatgcg aatgctttag aaatgtgtgt
      541 agggcaactt cgagcctcag cttttggtga agaggtttat ccttcgattt atgaaaaagc
      601 agctatccta cttatacaat tgataaagaa acatcctttt cacaatgcaa ataaacgtac
      661 tgctttctta gctacttttg tctttttgaa aatcaatgga cagcttttag ctattgatca
      721 aaaagatgct gtaaatttag cggtatatat tgctacgtat gataaggatt tcgatcaact
      781 aaaatatgaa gtgatcaaca ctataaagac acatacgcag cccatttaag gagttactgt
      841 atgtgtcttt atagtgttat tagctgctat agcgaaataa ttgaagtaaa ttacaaatag
      901 ctataattca aatccaagta tatagaaaac gtaaattttc tatatagttg gattaagata
      961 acgactattt attttatcat atttttactg taccctatac ttttacttgg tatatttatg
     1021 aataatcgca aatttacccc tatactacta gtttgtaagt tagattaata aaaatactaa
     1081 agttatttgt tcttttatta aatacaccta caacttataa attgatggta tttagataac
     1141 gcgaaagaat aaaaataaca gctgatagta aagtttgttg acgattgcta ctcaatcgaa
     1201 agtgagttag tgcgtatgaa cttgcttctg aaaacttatg aaatgaaaga ccttttacat
     1261 cttgcagaaa tcgttactgg gattaaacta agcaataaaa actaatgttc ccctcattct
     1321 ttgaacttct actatttgat ttatttattc tgataaatga cgatttcacc ttcaggatct
     1381 tcaaatcccg tatagaattt atttaagatc tcttcagtat cagtaatagg ataggcgata
     1441 ggccacatac cctttgatgg ttagaataaa ctgctcaaaa tctgtatcgt atgttggctt
     1501 tagcatatta acaaaggcta tctccaaatt ataaaccata agcgttgaat cgttcttaac
     1561 aatttcaatt cttcctaacc caaagtcaga agatataatt accggacttg ccttaccctt
     1621 catgtgggtt gttgagattc catatttaaa gggaattgtc ggtactatcg gcggtctgaa
     1681 aaacatccca aaaataaaaa aatctttccc ctgctagtct cctaagtccc tttgcagcgg
     1741 atatggcacc ataatctcat tttatcgaag tgagtcatgg tttatctgtt ggccaaccaa
     1801 aattgataca atctaacgat gcaccctcta cggcattcta ggggagtgca cttgcattca
     1861 cccaataaaa accggcagtt agcaaagaac ttatgtagtc gtatgttctt actgttaaca
     1921 tacaagaggt ctcctttcca caattgctta gcagtaaacg ggaatttaca aagctaatct
     1981 cttccatttt cttatctttg ttctaaaagt cccaaatgga gcaactgtat ttacatgaat
     2041 aaatttatat acttcccata cagccgtttt ggttgcctcg tctgcccatt ttcttttgtg
     2101 tgcagtgaat agatcttcat cactcattga atcaatcatc atgttaatat catcaatatt
     2161 acgattgaga atttcctcta attctttcaa tggtagatgt gcataggtat ttgtaaacca
     2221 cttatataac tctcctaact gattccattt aaattgatca gaaggcgttt taacagataa
     2281 tccatttctt tcatcatttt cccattttag aattaaattc gtccaaccaa cttgatatgc
     2341 taaattttca gcaggtgttc tatccacttc ctcaactctt ttatccttca attcttcagg
     2401 aatagtttca aattctaaaa tatatttagt ataagtccta tttatttctt tttttaattc
     2461 ttctttattt ttatatgttc tcattatatt acctccataa attcctaatt gtctccttta
     2521 attcatctat aatttcatcc acgatatttt aatccgttct acaatgcata tctgatatgc
     2581 attgactgtc taactcatat gtgaatgatt tataaaatat cccaacgtct catctaaaga
     2641 aatgttgatc gtcagcaagg agctaaaaaa tacgaatata tttcttttgt agtaaaatcg
     2701 gactggtttg catatcattt tcttcgtaaa tatcaaaatc atgttaacta ctatcaatta
     2761 ctaataaaaa ctaccacttt aagcgttaag aactgttaag tttagttaag tgaggatagt
     2821 tcacaaaatc cattgttaaa cttcacgaaa gtggtaaaac tcaaaatgct ttatatagga
     2881 ttacagcatc gctctttctt cgattgcgcg ttgggtaaaa aatattatga agtaaaaatt
     2941 gacgatgaca cgttccttac ggctcatcag atgaaacagc tacaaaaacg aaatgatcaa
     3001 ctcgaagaaa atttaattct aaaaaagcga ttgccatatt cacgcctcgc tcgacgaact
     3061 attaaaggtc aagatttacc tgaagatcat cctttttagg aaattgaagc tttttatgtt
     3121 gcacaatgca tttataatac tacaatgatg ttttcaccag atattcttct agggtgcggt
     3181 gtaatgaaac agatacactt gcaaaagaaa attcaccgcg aatttactaa aattatgaat
     3241 aattatgtta atcttccgaa atttttttcc aaaattaagg gatcaagctg gtgttataga
     3301 ttgtttaagg ttggcaaaaa aataacttct ttttaaacaa ttatagaaaa ccgatactct
     3361 gttaagttgg ttgacacggt atcgattttt atgactttct tattctgaaa cttcactaac
     3421 ggacagtacc taaaaagtct atagtatgga cgtttacgag tactatttta tcaaaaatgc
     3481 tgctcatttc aacttatatg ttttagtgaa ctacccccac ttagctaaac ctgacggttc
     3541 ttaacgcttg aagtgggagc ttcttgggaa cagagcgtac ttgata
//
LOCUS       DADVXB010000186         3455 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.192, whole genome shotgun sequence.
ACCESSION   DADVXB010000186 DADVXB010000000
VERSION     DADVXB010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.192"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..2232)
                     /locus_tag="KB902_002613"
     CDS             complement(<1..2232)
                     /locus_tag="KB902_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809383.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNMPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="KB902_002614"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="KB902_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          968 a          764 c          548 g         1175 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 catattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatc
//
LOCUS       DADVXB010000187         3338 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.193, whole genome shotgun sequence.
ACCESSION   DADVXB010000187 DADVXB010000000
VERSION     DADVXB010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.193"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1007
                     /locus_tag="KB902_002615"
     CDS             <1..1007
                     /locus_tag="KB902_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809384.1"
                     /translation="TIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRGERN
                     PRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGNNIKNIRKSKNMTQTDFAELM
                     GLSRSYIGDLENNRRNPSIKTLEAIARALDVPIVALINDSSTDNIVEPYESLTAENIL
                     LKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIRKKLGMTMEQF
                     GSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEEYITSYLIGIG
                     YELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYYSKEFEVTQIP
                     "
     gene            1021..1803
                     /locus_tag="KB902_002616"
     CDS             1021..1803
                     /locus_tag="KB902_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809385.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            1843..2454
                     /locus_tag="KB902_002617"
     CDS             1843..2454
                     /locus_tag="KB902_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809386.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            2898..3047
                     /locus_tag="KB902_002618"
     CDS             2898..3047
                     /locus_tag="KB902_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809387.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFD"
BASE COUNT         1336 a          427 c          623 g          952 t
ORIGIN      
        1 ttactatagg gggcgttact ttgaatagaa taaaatttta tattgattcc agtaaaaaga
       61 ccattaaaca aattagtaca gaaactggta ttaactatac aactcttacg aactattacc
      121 gtggtgagcg aaatcctaga aatactgaaa catggaatat ccttgctgat tatttccatg
      181 ttcctgtaag ttatttgatg ggattagacg aaacaaatgt tgaactcaaa aaccttaata
      241 ttggaaacaa catcaaaaat attagaaaaa gtaaaaatat gacacaaact gattttgctg
      301 agttaatggg tctatcacga tcatatatag gggatttaga aaacaacagg aggaatccca
      361 gtataaaaac actggaagct attgcaagag cattggacgt tccgatagta gcattaatca
      421 acgattcttc tactgataat atagtagagc cgtatgaaag tttgacagcc gaaaatatcc
      481 ttcttaaaca agaaaatgag gaattaaaat atgaggtaga aagcttacga aaaagattgt
      541 atgaaatcca acaagtagta aatcaaggag ctgaaaaaat gattcccaat ctaaaagacg
      601 taagtaaaag aatcaaatat atcagaaaaa aattaggtat gactatggag caatttggtt
      661 ctcatttaag caactcacct aaaagtacaa ttgctacttg ggaaagtggt agaaatatac
      721 cttctcagaa aaagttacag ctgattgcta tagtaggaga aaccaccact gactggatta
      781 aatggggaac tttagaagag tatataactt cataccttat cggtatagga tatgagctat
      841 atattaaaga ctttccagag atacctcaca aagtctttaa agacattcaa gaaaaatata
      901 gtgatacgtt ttcgttagat aaagactatg aattattgga ttctataata aaaaatatat
      961 ttacaaaata ttactcaaaa gaatttgaag taacccaaat tccataagag aggtgattgt
     1021 atgaagccaa atccttcaga agcaggaaaa cgaatcaaac aattacgcct ttcatgtggt
     1081 tttactatgg aagaacttgg aaggaaaata gataattcac cacgtgcgac catatccaac
     1141 tgggaacgtg ggaccaattt accaaatcca caaaagctga aattattatc aactatcact
     1201 aattcaacaa ttgactggat taaatgggga actttagaag aatatataac ttcatacctt
     1261 atcgatatag ggtatgagct atatattaag gactttccag aaatacctca caaagtcttt
     1321 aaagacattc aagaaagata tagtaatacg ttttcgctaa ataaagacta tgagttattg
     1381 aatcctataa taaaaaatat atttacaaaa tattactcaa aagattttga agattatcga
     1441 gacatagaag ttaaaccaga ccctaaaaag gtagggagaa aaattcgttc tattagaaaa
     1501 aaattaggac ttactatgca ggaatttggg tacgaggttt ctaattctcc tagaagcact
     1561 gtgtcaacat gggaacatgg tggtaactta ccgaacaaag ccaaactaaa aaaaattgca
     1621 gacattgcga attgtagtgt agaagatttg ctttttgatg aaggctttat ttctgaaaaa
     1681 tcccaagtta aattgataaa tgaactcaaa gaagaaaatt caaagctaaa agaaaaaata
     1741 aaatactatg aatgtttatt tgatggtata gagagtctgc tgaactcacg aaaaaattcc
     1801 tagttaatta aactagagta aaattatttg taggtgttaa atatgttagt tggctatgca
     1861 cgagtcagtt cagatgatca aaatttggaa agacagcttg aagaatttag aaaaattggt
     1921 gtcgaaaaag tatttgctga gaaaaaatct ggacgtaaca cagtagaacg gccagagttc
     1981 aataaaatgt tgtcatttgt cagagaaggg gatacgcttg tttttgagtc gcttgaacgc
     2041 ttaggaagaa attctgatga aatactagaa acagtatctt ttatagataa aaatggtatg
     2101 ggcttaatgg ttttgaattt accaatttta gatacaaaat ttggtgatcc aaacttagaa
     2161 aaacttgtta gaagcttagt aattaacatt ttttcttgga cggctcaaaa tgagagggag
     2221 gaaattaaga gaaaacaaaa acaaggaata gcaattgcga agaagaaagg agtctataaa
     2281 ggaaaaccct acgaatattc ttctactgca aagaatccac aaaagaggtt tatctataat
     2341 gaaatagtaa gaatgcttgg agaaggtgtt ccgattaagc gaattgcaga aaaaacagga
     2401 acaaatagaa atttagtcta tagaataaag aaaagaataa gtgaatctga ttgattttaa
     2461 gttctttgag aaatcaatgt tacgagagaa ggattctaag cctgtttcaa acttttaagg
     2521 tgtacaatta tacaaagaag cttctaaaca aaagaattaa ttttgtggca gtcaagtaac
     2581 gacagaaata gaaaagaaag aggctatgcg agagtgaatc aacaagttaa ttgggttaat
     2641 gattttgaaa aagaatttcg actgaaattt tttggaaatc ctacagcaga aagtacagaa
     2701 gaaaaaaatt atgactggtc agaattttag gttgcatatt cgattcaata agtgttgaag
     2761 ataatagttc tcttacgcca cagtatacaa cgttagaata tgacgaaaac agattcaata
     2821 catttccttg caataccatt caagaatcaa ttgataagca tgagtgataa ttgattatct
     2881 acaggaaggt gttttttatg aaactagaga tcaaagaagt tgtctgcgat tggggaattt
     2941 atgtagacgg agaaacatat ccatttatga tttttaatag taaagcaaat gcacaagaga
     3001 taatgcgtat catggagttg gataataagc acgaaagatt tgattaagta aaaaaaatgg
     3061 agaatgaatg tgaagcagtg gaataccaaa aaacatgcgc caataataag tatattttag
     3121 gtgcaatggg attaggtaaa tcagcttcta ttaaacaggt ctacgaagaa tcacaggaga
     3181 attgcgtata tgaaaattcg aattaaagag tgagaatatg tgggagctaa tttatttagt
     3241 tttatactta ataggaaaat caactgaatt tgtatataac aataaggtaa tatttatatt
     3301 gttcttaata gtttgtatta tcgtatttga tgtctatg
//
LOCUS       DADVXB010000188         3283 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.194, whole genome shotgun sequence.
ACCESSION   DADVXB010000188 DADVXB010000000
VERSION     DADVXB010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.194"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            3..587
                     /locus_tag="KB902_002619"
     CDS             3..587
                     /locus_tag="KB902_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6809388.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1857)
                     /locus_tag="KB902_002620"
     CDS             complement(664..1857)
                     /locus_tag="KB902_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6809389.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1921..2301
                     /locus_tag="KB902_002621"
     CDS             1921..2301
                     /locus_tag="KB902_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBB6809390.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="KB902_002622"
     CDS             2375..2737
                     /locus_tag="KB902_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809391.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1115 a          537 c          622 g         1009 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gtttgtctct ctgatatgat
     3241 ataaaagttg ctacggcagc caaaaacgaa tcgggaaaca ctc
//
LOCUS       DADVXB010000189         3137 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.195, whole genome shotgun sequence.
ACCESSION   DADVXB010000189 DADVXB010000000
VERSION     DADVXB010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.195"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            69..1808
                     /gene="yfcC"
                     /locus_tag="KB902_002623"
     CDS             69..1808
                     /gene="yfcC"
                     /locus_tag="KB902_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBB6809392.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            1965..>3137
                     /gene="iadA"
                     /locus_tag="KB902_002624"
     CDS             1965..>3137
                     /gene="iadA"
                     /locus_tag="KB902_002624"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBB6809393.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFE"
BASE COUNT          955 a          533 c          743 g          906 t
ORIGIN      
        1 gtataattca tttgattatc cattttttat tcatcaaaat tactgaaaaa agaaaggaag
       61 aaataaattt gaagaaaaca aattcttcag gaaaaccgaa acgcgacttc actaaattat
      121 cgacacccca tacgtatgtc attatttttg gtgtagtcat ctttgcatgg atactgactt
      181 ttgtcgttcc agcaggaaag ttcagcacgc aagatattga atacaaagat gcaaatggcg
      241 aaacaagtac tcgtactgtt ttacgtcaag attccttccg ttatgcttac gagctggata
      301 agtcgtatgt gtttgatcaa ttagaagaac tgcaagatca tccagcagaa cgtgaaaaac
      361 tggatgttcc ggaaaaagga ttggaaaaag tcattgctga cggagaaaaa aatcttacgc
      421 aggaaaaact agatgaaatc tccttgacag atgatgtgct ttacgatcag tacggcgaaa
      481 atatctatga tacttctaaa aaattgcata aaacagccaa aatatgggga acagatgatt
      541 ttggcggctt tggtttctta aattttgttt ttgaaggact agtatctgga gataagtatg
      601 gatctgctgt agggatcgct gcattgatcc ttgttgttgg aggtgctttt ggtattatta
      661 tgcgtaccgg agcgatcgac gcaggtatct atgcgtttat cagtaaaact aagggactgg
      721 agcgtttagc tttaccgcta ttattctttg ctttttcatt cggtggcgct acattcggga
      781 tggcagaaga ggtaattcca ttctcaatgg tgatggttcc atttgtcatt gcgttaggat
      841 atgactcgat cgtagcagta accgtgactt atgtcgcatc tcaagtcgga aatgcgacct
      901 cttggatgag cccgtttagc gtagcggtgg ctcaagggat tgctggaatc cccgtgttgt
      961 ctggtgcgac attccgattg attatgtggg tagttgttac tgcattagcc gctggttata
     1021 tgatgatata tgcagaaaaa atccgtaaaa aaccagaaag ttcgttgact tacaaatcag
     1081 atgattattt ccgttctcat atcaaaaaga catctgatga aaataaaaaa ttcatgcttg
     1141 ggcataaatt gatcttatta gagatgttag ttgtccttgt ctggatcgtt tggggcgtga
     1201 ctcaaaaagg ctattacatt ccagaaatcg cttctcaatt ctttgtgatg ggattagttg
     1261 ctggaatcat tgctgttctt ttcaaattag atggaatgaa agtcaatgac atcgcttctt
     1321 ctttccaatc tggtgcagct gatttagctg gtacagcaat cgtagtaggt atggccaaag
     1381 ggattcttct tgtcttggga ggatctgatg catctgttcc ttcagctttg aatacgattt
     1441 tgcatgggat cgggacggcg ttgaccggtg ttccagctgt cattggtgct tgggcgatgt
     1501 acatcttcca aagtttgttc aacttggttg ttacatcaaa ttcaggacaa gcagctttga
     1561 ctatgccaat catggctcca ctggcagatt tagtaggtgt atccagacaa gtagcagttc
     1621 ttgcttatca gcttggttca ggttttatgg acgcttttac acccgtatca gccagcttga
     1681 ttggtgtgct aggtgttgca cggatcgaat gggcaaaatg ggcaagattc caaatcaaga
     1741 tgcaaggatt cctgtttgtt ttaggaacta ttttcatcat gattgccatt gcaataggtc
     1801 tgcagtagta ctggagacct gtaaataaaa aagtaatcca aacagtagat aaggactcca
     1861 agaaccgtca ttttacggta aaatcaaagg agtaaagatc ctatcgtttg gattattttt
     1921 taagatccta tcatcagtta tacttaaaga aagaggaaaa atgtatgaaa atcattcgac
     1981 aaattgaagt gtttgcacca gattacttag gaaaaatgga tgtactgatt gccggtggga
     2041 agattttggc tgtagaagaa cagctagaag gcggctacga aggagtggaa gtagaagaac
     2101 tttcaggtga gggaaaagta ctaaccccgg gtttcattga ctgtcatttc catattttag
     2161 gtggaggagg agaaggcggt tatcaaaatc gaacgccaga agtcacattg agccaattga
     2221 ctacagctgg tgtaacgaca gttgtcggtt gtttgggaac agacggagaa ggtagagata
     2281 tgactgcgtt gatcagcaaa gcgaaaggtc tggaagcaga aggaatctcc acttatgtat
     2341 acgaaggttc gtaccgattg ccggtaaaaa cagtaacaga ttctatcatc aaagactttt
     2401 tgacaattga taaaattatc ggaatcggag aaatcgcagt atccgatcac cgttcttctc
     2461 agccaagttt tgaagagttc gctcgtgcag tagcagatgc tcgtgtagga ggcatgttat
     2521 ccggaaaagc tgggatcatc aatgtccact taggcggagg aaaaagaaag ctagagctat
     2581 tgacacgaat cgtagaagaa acagaaattc cgatcacaca atttttgcct actcatgcaa
     2641 atcgcacacc agaattattt gaagcttgcg tggcatttgc caaacgtggt ggcacgattg
     2701 acttcactgc tagcgaagat cctgattttt gggagaagac agatggtgaa gttcgcttca
     2761 gcaaagcact gaaacgattg atcgaggaag atgtttcttt agataatttc acgatgacct
     2821 cagatggaca aggaagcttg ccttattttg atgaaaacaa tcatttccta gggttaggag
     2881 taggaagtgc caaggcattg ctagtaggga tcaaagaagc tgtgcaaaaa gaaagtatcc
     2941 ctttggaaat cgccttacga gctataacca gtaatccagc acgtatattg aaattggata
     3001 aaaaaggaaa aatcgaaatt ggtgctgatg cagatctgtg tatcttggat aaagaaacgc
     3061 ttgatattga tacagttatc gctaaaggag aaataatggt ccaagaaaaa gaagtcaaag
     3121 tatgggggac tttcgaa
//
LOCUS       DADVXB010000190         2983 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.196, whole genome shotgun sequence.
ACCESSION   DADVXB010000190 DADVXB010000000
VERSION     DADVXB010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.196"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(74..616)
                     /locus_tag="KB902_002625"
     CDS             complement(74..616)
                     /locus_tag="KB902_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBB6809394.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            751..1140
                     /locus_tag="KB902_002626"
     CDS             751..1140
                     /locus_tag="KB902_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809395.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1144..1908
                     /locus_tag="KB902_002627"
     CDS             1144..1908
                     /locus_tag="KB902_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6809396.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2037..>2983
                     /locus_tag="KB902_002628"
     CDS             2037..>2983
                     /locus_tag="KB902_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6809397.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
BASE COUNT          959 a          501 c          613 g          910 t
ORIGIN      
        1 tcaaaataat aaataaaaac tgtctaacat ttaaaattta atttagatat tagacagttt
       61 ttaagtttgt gagttatttt ccttgtcgtt ttctcacttt tttagtccag aaaccacctg
      121 aaatatattt tggctcataa gaaatgataa aagcacgctc ttcgatttct ttgatcaggc
      181 gatacagttc acgttcgctt tttctaggag aaagtatttc gagaactagc cgctcacctt
      241 ccagccccat tgcagaagtc tgtgtcacac cataaccgtg ttctctcagt atacccggca
      301 aacttttatc ttctgcgcta tttgctggca aaatcgttgt gaccatgatg tatcctaatg
      361 ccaatttgtc ttcaatcaaa attccgacac tgatacctac tgcgtaacct aacgcataga
      421 caaataaatt cagtggatta tctaaacgat ctaaaacaag ggataagccg acgatataaa
      481 tcgtgatctc gaccatactg acaagtggag caatcagtcg atagcctttc attgtcaaca
      541 tgaaacgtaa cgtgttcaga gtgatataag caaaattaat gaggaagatc atccccaaca
      601 tttttggatc aatcatttgt aaaactcctt tcatttatat aacaacaata tcaaaaaaaa
      661 tcgtaagtga agaaaaattg aaactttata catacaaaaa aatgataaaa tgattataat
      721 agaattataa agataggtta ggtgattaaa atgaaaacgg tcaatcgtgt gttttgtgcc
      781 agccacgtgc taagtctcct tctcagtata tacttaggtg tctattcgat tcaacagcca
      841 attgaggtag agaacattgt ttttcagatg tcgctgacag atggtttaat tttaagcgtt
      901 tttttctttt tgatactgtt tattggtaat attttcggta gcgttgccag ttttttgaat
      961 ttttctattt atccactcct ttcgctagca ttaggagtgg tgggactttg ttctctgtgc
     1021 ttatttcccg agccattcag tcctgcattt atattatttg gtacactgaa cctgttccag
     1081 acaactgttg gagcatggtt gctatggcga tcaggaaatt taatgaaaat aggtgagtaa
     1141 caattgaatc caattatatt gaaacgttct gtccatcata ttccagtgtt agaagttgtt
     1201 ctgaaagaat taagagagga acgtattccc gttgtcatct attatcacgg atggcagaca
     1261 agtaaggagt tagttttgac gcaaggaaga aaaattgcgc agcagggcat tcgtgtgatc
     1321 ctgccagatg cgatgaatca tggggagcgc aaacagccgg tttcttctat tccatcctat
     1381 acattttggg atagtatcta cggaaatctg tttgaatttg acacacttat caagcattta
     1441 gaaaaaagag gtcttctaca tgatcagctt gcagttggcg gggtttcgat ggggggaatg
     1501 acaacatgcg ccttgttggc taaacatcct catatagtag cgggcgtgtg tttgatgggt
     1561 tcccctgcac ctttggaata tggaaaagaa atcgtaaggc gcgcatcgga atataattat
     1621 gtcgtaccaa aagactattt tgatttgatt tcatgggtta agagctatga tttgtcattg
     1681 cagccggaaa agttagctgg acgtcctctg ttcttttggc atggacaagc tgacgaaaaa
     1741 atcccttata tacaaacgga acgatttgta gaaaaaaatc ggcataagtc ttacggaaaa
     1801 gaaattgttt ttcgttcctc aaaaacacag cgacatatgg tacaaatacc actaatggaa
     1861 gaagcttcca cttttttagc aaaaaatttg ataaaaaagt ataaataatt gaaacggaaa
     1921 atcactcatg acgatagagg attttccgtt ttttattttg ggctataata aactctgtta
     1981 ggaaaatttg gtataattga tagtaagaat gacaacatgt tagaaaggaa gagagcatgc
     2041 ccactttagc agatgttgca aaacgtgcca atgtttcaaa aatgacggtc tctcgagtca
     2101 tcaatcatcc ggaacaggtg actgacgaat tgaaagagtt agttttctca gcaatggctg
     2161 aactggatta ccgtccaaat attgctgcaa aagcacttgt cacgaatcgg tcgcagatca
     2221 tcaaattatt tatactggaa gaaatcgaca caactgagcc ctattacatg aatttgctga
     2281 tgggaatcgc taaacggatc ggtaaagcgc attattctct ccaattagtt acaaatgatg
     2341 ccttcgacgt cggttcttgt gatggataca tcatcacagg tgtcagaaaa aaagacttcg
     2401 attggatcga ccgtttggaa aaaccagttg tcttgtttgg ggaaaattct gaaggatatg
     2461 attatgtaga cagcgataat gaatatggta cagcaaaagc aacgcaatat gccttagaaa
     2521 gagattatca aacgattatt tatatcggta tcgaagtgga cgagcctttt gaaatttcaa
     2581 gggaaactgg ttatttatct gtgatgaagg aagttgatct tcctagtaaa atcttgcggt
     2641 ttccaaatca ttcgacagaa gtagaaagat atatgacaga aaactgggca gattttacag
     2701 ataaaacttg ttttgtatgt agttcagatc ggctagcact aggagcagta agagggatta
     2761 taaatgctgg aggacacttg cccgaagaat ttggtgtgat tggatttgat ggggtatttt
     2821 tagaccaaat cagttcacct aaattgacaa cgatcaagca agatattata cgtatgggtg
     2881 aagtatgtgg agaaatgttg ttaaaaaaaa tagaagaaaa aggggcgagt caaggttatc
     2941 gtcgtttttt tcctgaacta gttatcagag agacaacgaa tta
//
LOCUS       DADVXB010000191         2925 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.197, whole genome shotgun sequence.
ACCESSION   DADVXB010000191 DADVXB010000000
VERSION     DADVXB010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.197"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..134
                     /locus_tag="KB902_002629"
     CDS             <1..134
                     /locus_tag="KB902_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6809398.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(220..1314)
                     /locus_tag="KB902_002630"
     CDS             complement(220..1314)
                     /locus_tag="KB902_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6809399.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1503..2264
                     /locus_tag="KB902_002631"
     CDS             1503..2264
                     /locus_tag="KB902_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6809400.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2379..2819)
                     /gene="fabZ"
                     /locus_tag="KB902_002632"
     CDS             complement(2379..2819)
                     /gene="fabZ"
                     /locus_tag="KB902_002632"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6809401.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT          941 a          576 c          486 g          922 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc ataacctata aaaaaacaaa ataaaaaagc agaaataact
      181 ggctatttct agcggattat ttctgcaata actaattatc tattttttat tttcaattaa
      241 tttaaagctt gaccatggtt tcaaaaagtc aaggaggaat aattcgtcat cggagattct
      301 tcctacaaca ttgacacgtc cgtcgttttt catatccttc aaggcgattt gtgtttctcc
      361 tttgtattga ccgtaccctt cattgtcaat cagtacatcc ccatgatgca tatctcgcgt
      421 attatgaggc gggaaatctt tatctttgta gtatacacga gtcatcgttg aacgaaggat
      481 atattctgag cgatcccctc gataactatg aaggttatca aacaagcaga ttcgttcgtt
      541 ttctgtaata ccttcttccg tatctacttt caatgttgga taatccgcgt taaatgcttc
      601 tgccatttct ttcaattctt cttcacttgc gtacgcattt ccaatagaaa tatcatcaat
      661 caatcctgta aggattaaat gcttcacttg tgtcgcaatt tcaagatctc ggtggtcttc
      721 cagcgtgcac aagccatctt gcgtaggcca agggccaaac tcagcagatt gcgaattgac
      781 gaatgccatc gtattcaaat tatattttct gaatttttct gaacaaaaaa caaagtgttc
      841 gtatcctaaa ccagagtatc gatgaggata aaaattatga gaacctaata aattatccgt
      901 gtttggcgaa taactcatga tgttgtcaac gtaattcgtg cccgaactca tattgatctc
      961 gattttgata ccaaaaggat tgcgcgtcat ttttgcttct tctgctcctg tgaatccgat
     1021 atctaagcgg accccgtagg cacccatctt atggaaaaaa gataagtcat cgtaagaaat
     1081 ctccaactgt tcaaataacg ctggattgat atcaaccatt acttccatgc ctaggctatt
     1141 cgcgtaatca actacttctt taaattctga aagaactttt tctttatcat cattgatctg
     1201 cagcaaactg gtaaaaaccc gtttataccc atacttatga gctaaatcca agtacgcttt
     1261 gtccttttca aatgttgacc gttctggata aatcgagatt cctaattttc ccatattacc
     1321 atttcctcct gcatcttttc gtttttgtat ccacttacat tatagcaaac acaaagtaaa
     1381 tggtctacac cttttctttt tcttttaaaa taaatgataa attccaataa tttaagtagg
     1441 tattttccct ctattttgtt atcattaaag ataacaaaat agtaaattgg aaaggaacag
     1501 ttatgaagaa aaataaagtt attttaagta ttagtttagc agcagcattg ctgtttgctg
     1561 ctggttgttc tgcaaacaac acgacttctt ctagttcgtc tacagaaagt tcaaaaagta
     1621 catctactgc ggaaagcacg actgccagta gcgtcgattt gaacgcattg gaattaccac
     1681 aattgacgaa agatgtcgcc gaaaatgaag atctggtcga aatggtgacg aataaaggca
     1741 caatcaaaat caaattattt cccgaacacg caccaaaagc ggttgaaaac tttatgacac
     1801 atgcaaaaga cggttactac aacggactga ctttccatcg cgtcatcaaa gatttcatga
     1861 tccaaggtgg cgatcctaaa ggcgatggca ctggagggga aagcatttgg ggagaaggat
     1921 ttgaaacaga gatcaacaac cacctttata atataagagg tgcgttatct atggctcgct
     1981 cacaagatcc taacagtaac ggcagccagt tctttatcgt tcaaaataca gatgatatgc
     2041 atgatggtct tttaaaagac gactatcctc aagcaatcat cgacgcttat aaaaacggcg
     2101 gttatccttc actagatggc cattatactg tcttcggcca agtgattgaa ggaatggatg
     2161 tcgtggatgc tattgcaaat atcgaaacag atagttcaga caaaccaaaa gaagaagtaa
     2221 aaatcgataa aatcaatata ctgcaagaag caaaacaaaa ataaaaaaat aacgtctgaa
     2281 tcctgcatag atgacaacgt atgctaggat tcaggcgtct tctttttaca taaaaagcaa
     2341 gtaagcttcc ttttgttttg ctatatcagg ttttatagtc aagcattttg gttgacgatg
     2401 aacgtgaact cgcactcaca gactttttta tcatctacat atgctgcaga taacgctgta
     2461 ccgactgatc ccttcatttt ggtgatttca aaatgacatt tcagcacatc tcctggaaca
     2521 actttttgac ggaatttggc cttattgatc ccaccgatat aagctctttt tcctagaaac
     2581 tcttctgatt ttaggataag tatcgaacct gcttgtgcca gtgtttctag aatcaacgca
     2641 cccggcatca ctggattgtc aggaaagtga ccttggaaaa aatcttcatt gattgttaca
     2701 ttttttgtcg caacgatctt ttttcctggt tctaaagtat ctacataatc aatataacaa
     2761 ataggataac gattaggaat caattccatt acttcagtag cagataatac gtaagacata
     2821 attaaactcc ttctttcagg caattgccat tttcattact ttgactatca aagtatcata
     2881 ttcctaaata tttagcaatc tttttttaat ttaagaaaaa atagt
//
LOCUS       DADVXB010000192         2888 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.198, whole genome shotgun sequence.
ACCESSION   DADVXB010000192 DADVXB010000000
VERSION     DADVXB010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.198"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..221)
                     /locus_tag="KB902_002633"
     CDS             complement(<1..221)
                     /locus_tag="KB902_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809402.1"
                     /translation="MKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKTIDWIKWGTLE"
     gene            527..715
                     /locus_tag="KB902_002634"
     CDS             527..715
                     /locus_tag="KB902_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBB6809403.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            761..1138
                     /locus_tag="KB902_002635"
     CDS             761..1138
                     /locus_tag="KB902_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBB6809404.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1698..2870)
                     /locus_tag="KB902_002636"
     CDS             complement(1698..2870)
                     /locus_tag="KB902_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809405.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
BASE COUNT          870 a          543 c          390 g         1085 t
ORIGIN      
        1 tcttctaaag ttccccattt aatccagtcg atagttttgt tacttaattc agcaatttta
       61 attaatcttt ctttgttggg aagggagaat cctcgttccc aattattaat atttcctttt
      121 tgagcatttc caattaaatc tgcaaattgt tccatagtca ttccaaaatt agaacgaatt
      181 gatttaattc ttttacctgt ttcaacagga tttggtttca tacaatcacc tcttttacag
      241 aatttggttt catagtatct tattcgctct ttgagttcta agttctcttt ctccaatttt
      301 tctatataat attcttgatc ctgtttcttg ttcaaaaaat gacctccaaa tttcacattg
      361 tgttacaccc tagtgttaca cctccaaacc ttattatact gtactttacc atatgataca
      421 atagggtata ccctattgtg acacttacat tctactttta atgtaaaaac tcttgacctt
      481 tatacgcata atgcgtataa taatatttgt aaggaggtag tcgcgaatgc cacttaccgg
      541 taaaaaaatg ctcaaactag ccaagaaaaa tggttggaaa gtggtgagga taactggcag
      601 ccatcatatt gtagccaaag aaggattccc acccgttcct attcctgttc atagtaatca
      661 ggatttaaaa aaagggacag agcagaagtt actaaaggac ttagggctga aatagcccag
      721 tcctttagtt cattggatta actcgaaagg agtggtggaa atgaaaaaaa gttaccctgt
      781 aattttttct gctgaagaaa atggctactc agtagttttt cctgattttg ctggagcaac
      841 acaaggagat aattttgaag aagctatgtc caatgctaaa gaatttcttg atgggattct
      901 agcttactat attgatgaag atatttcagt tccttctcca acagatattc atcaactaaa
      961 taatttgggc aataacaaaa ttgtttctct tattcaaagt gatccttctc catttatcca
     1021 aaaaaagacc gtacgcaaaa acgtcacagt cccagaatgg ttagtagcta gaggggaaaa
     1081 agataaaata aatttttcta aagttttgac agatgcgtta ctaaaaatat acgagtaaac
     1141 gtaaatatat taataacaat ttagttgcct aatgacatag atagcggaat taaaagtaaa
     1201 atagtactca tttattgcag gttcccttag aatcaataca ataaatgagt actatttaga
     1261 ctgtttaact actagtaaga tatagcgatc atcagtttca gggttatccc ttggtgacca
     1321 tagttttgcg tatttttcaa ctcgttgcca aatcaacgat tctatttttt tatttctact
     1381 taactccaaa acggagtacc ttctttttct tcgttagctc ctatttaaga gccatgtcgt
     1441 tttatataac tctaaaacag aaactactga tcaattcaat aaagccttat ttgagaactg
     1501 tgttgtttta catggtttta aaacctgatt tcccgcaaac ggtttatccg taacatttga
     1561 gaactgtgtt gttttacatg gttctaaaac ctcaacaata ttcgtccttc cgtctggtta
     1621 cacaacttga cagagctaac ccttcagtga gtgagtgtcc cctcactatt tcgttgccaa
     1681 atcaacgatt tcttattcta ctcactttta acttctattc catatctttt ccctttattt
     1741 attatttgtt ctttcaactg ataataagcc cattccccat aatttttatc tggttcagaa
     1801 atacagatta tttgcgtctt attgcggata gctgtttgaa taatttttgc cgaacattga
     1861 ttattatagg ttttaacaaa attgctttct cttttcttta tggcttccca tctatcttga
     1921 tctaattttc tttttcgacc atgaccgcct ttagaaaaaa ctcctcggct ttgctccctt
     1981 gatttcattg ctttaatttt atttttgaag ttacttatat atttgctgtc accaaaatca
     2041 atcacagatt gattgttaac taaacattta ccgctacaca aatcagtaaa ctttatggtt
     2101 aattcagctc cttctttgaa atctagctta tgataatctt tttcaaaaga aattgttaaa
     2161 ttcaaaaata aatttttccc ctcaaagatt agattactct ggtttaactt gtattgaccg
     2221 tccataatgc gttctaaagt taaagcgcta tctctggctt ttcttggttt tctacctaaa
     2281 tttactttaa acctaaatcc tttaggtaaa gagatataaa acttgtcagc tttgtgaatc
     2341 ttaatatccc gacctctgaa cggtaacaat ccatatttat ttttatttct atagattcta
     2401 ggtgttcttt gcccagtaac aattccaaca aaatcattgc taaaatcctt actagctttc
     2461 attttagctg aatctataaa atccgaataa tcaaagtcca atttttttgc tatatcacgt
     2521 attctggttt gactttttaa acctatagct tgtgtcaaaa cgtctctggc ttctttgttt
     2581 ttcgcaattc gtagtttaga taattccctt ttcgttttat ctaatttctt ttgatcgatc
     2641 acttcattac ttagtaaatt atcaattcgc tcttcaagac ttagctctct tttaatatac
     2701 tcatgatcca attcttttat agaattttcg atcaattctt caaacatcag ctgtttatat
     2761 accatattca gcgcttttac atattctcta ctatttttcc aaaaaaaacc aaaaaacgaa
     2821 tctctttcct cttgtgatcc atcaacatat acttctattt ttttagtcat agttattatt
     2881 gtcaattt
//
LOCUS       DADVXB010000193         2862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.199, whole genome shotgun sequence.
ACCESSION   DADVXB010000193 DADVXB010000000
VERSION     DADVXB010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.199"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            299..1624
                     /locus_tag="KB902_002637"
     CDS             299..1624
                     /locus_tag="KB902_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6809406.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1617..1967
                     /locus_tag="KB902_002638"
     CDS             1617..1967
                     /locus_tag="KB902_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809407.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1949..2134
                     /locus_tag="KB902_002639"
     CDS             1949..2134
                     /locus_tag="KB902_002639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809408.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
BASE COUNT         1004 a          448 c          546 g          864 t
ORIGIN      
        1 attaagaaac tgaatactcc tattttttgt ttttaaggaa agttttttct tttttgaatt
       61 tcttattttt ttctaatata actaagcaaa actggataat acgacactta ttttcaaatt
      121 ttcacaagac taatagtaaa tatccattta ataaagtgat acaatgtgtt gattttacaa
      181 atcaacagaa gaagtaggga aataacttac ctatgcttct ttttttgtac atttaatcga
      241 ttcttcttta caaaaacgaa cgtatgtttg tataatgtgg aagaatggag tgttatttat
      301 gatggattat tcaaaagagc cagtaaatga ttactttttg atcgatatga aaagctttta
      361 cgcaagtgtc gaatgtatag aaaggaattt agatccatta acgactgaat tagtcgtcat
      421 gagtcgagcg gataatacag gatcagggtt gattttagct tcttcaccag ctgcaaagaa
      481 gaagtacggt atttctaatg tcagtcgacc acgagatcta ccgcaacctt ttcctaaaac
      541 gttacatgtc gttccaccac gcatgaatct ctatattaag cgaaatatgc aggtaaacaa
      601 tattttcaga aggtatgtag cagacgaaga tttattgatt tactcgatcg atgaatcgat
      661 cttaaaagtg accagatcaa tgaatctttt tacgactgaa ggaacaagaa gtcaacggag
      721 aaagaagctg gctcaaatga tccaggagaa tattaaagaa gagctaggat tgcttgctac
      781 agtaggtgtc ggagataatc ccttattagc taaacttgct ttagacaatg aagcaaaaca
      841 taatgatgga ttccttgctg aatggacgta tcaaaatgtt cctgataaag tatggaatat
      901 tcctgaaatg acagaccttt ggggtattgg atctcgaatg aaaaaaagac tcaaccaaat
      961 tggtatcatg agtattaaag acttagctaa ttggaatcca tacactatta agagccattt
     1021 aggtgtgatt ggcttacagc tgtattttca tgcgaacggg atcgatcgaa cagatatagc
     1081 gatcccacca gaaccgacaa aggaaaaatc atatggtaat tcacaagtgt taccacgaga
     1141 ttataccagg agaaatgaaa tcgaactggt ggtaaaagaa atggcggaac aagtagctat
     1201 tcgtatcagg caacataact gtaaaacagg ttgtgtccat ttatacattg gcacgtcgat
     1261 cttagaaacg agaccaggtt tttcacacca gatgaagatc cctataacag ataatacaaa
     1321 ggaattgcag aattactgtc ttttcttgtt tgataagtat tatgaaggac aagaagtaag
     1381 gcacgttgga ataacctata gcaagcttgt gtacactgat tcgcttcagc tggatttatt
     1441 tagtgatcca caaaagcaaa ttgacgaaga aaatttagat aaaattattg acaagattcg
     1501 gcaaaaatat ggttttacgt cgattgtaca tgcttcttct atgttagaag gcgctcgtag
     1561 tattactaga agtacattgg ttggtggcca tgcaggcggc gcaggagggc ttaaaaatga
     1621 ttgattataa tgatcgtgga cgtttaaagt gggcaggttt ttatttatct gatcatactg
     1681 aaaaaattga tgccgacaat gaacaacgag ccaatcaaaa tttggcaaaa gaacaaatga
     1741 cgactgaaga ggttgcggaa gtattgaacg ctgcagtcat aaaaaataga tcagtatgta
     1801 ttcaaaaaga agaacgaaac gctgaaggat actatccaga agatattgtt agcaagatct
     1861 taggtagtga tgagctgggg atctacgttg gaaaaaacaa agttcactac gacgaaatac
     1921 gtcatatcga attttaccag gataataaat ggggtcgatt agaatgaaca ttatccagca
     1981 atatgagcta aagtatataa cctttgatca gctatcagaa gagatttggg gttatggcca
     2041 gcgtttgata aatgaggttg gtgttgaacg cttctctttc tatgtagaag ctgcagcagg
     2101 ataccataaa tacgaatact atattggcta ttaaagtgca ataaaattat atttctttta
     2161 tgttttacat tttgtatcaa ttctgataaa attacctata ggtaattaaa aaatataaaa
     2221 aaactagtta caaccttagg acgttgtaac tagcttgaag catactagag ctaactaaaa
     2281 tagcactaga aagcaatgtt aaacccgtcc aacaaacttg atttaacatt gagaccagct
     2341 tattcagcta aatatagttg aataagcttc ttttgtttta aaaaaacaaa aggtgtacta
     2401 cgaataacgc aagtaaaaga aatactatta caaccagtag gctacaagta agtattacta
     2461 aacattgcgt agttagaacc tttgctctat tgtctaaagc cacaaaatta gagatcagct
     2521 ttatgatgct aagagcgagc tgcatccatg cggacatagg ttcttttgac actattaatt
     2581 ctccttttta ggataaggga aattgctagt agttttttca ttagcaccat cccccttcat
     2641 ttgattgagt ctagtgctgc tgtgatagtt tgctgtttaa tatgcttaca ttcttattat
     2701 aacataaatg aaacaaacac atggttagag gtcgtatcaa tcaaaatagt gtctcacaaa
     2761 cgatttatta cttactcctg ctgactaacg gactgttctt cagtaactgt aactatatgt
     2821 ttgttaaaac caccattacc tgtagataaa aaccaatata tt
//
LOCUS       DADVXB010000194         2856 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.200, whole genome shotgun sequence.
ACCESSION   DADVXB010000194 DADVXB010000000
VERSION     DADVXB010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.200"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            561..842
                     /locus_tag="KB902_002640"
     CDS             561..842
                     /locus_tag="KB902_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809409.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLEKFIAIQTKNTQVLNDYVHTNNQLIETLIGGK"
     gene            844..1260
                     /locus_tag="KB902_002641"
     CDS             844..1260
                     /locus_tag="KB902_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809410.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKT
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1421..1687)
                     /locus_tag="KB902_002642"
     CDS             complement(1421..1687)
                     /locus_tag="KB902_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809411.1"
                     /translation="MAFRFRCDRGGRKMTEKFPYEYYQNLEKLESAIQLVKLDLLDEN
                     LLKYKNITPERKGKLKKMQQLFDEEDGISDVIFDTWSEFHGEYN"
     gene            complement(1645..2619)
                     /locus_tag="KB902_002643"
     CDS             complement(1645..2619)
                     /locus_tag="KB902_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6809412.1"
                     /translation="MGKKRTIVNEWEKLTAPSNRRLNVGESVKMIKMDWSIDRITIVG
                     TLNENIYYHTQNDVLILDFEQLMRVNEGNGHLKAVGNNGWQLVDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKKFIHDLFLEPHFSRADVACDLIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQEAKRKIVPKEVETWWRLELQ
                     LRRGKATDWYEMVQESLDSFASPHYFPEDVKTLDRVMIKGLLYDHSEWSTISRDLKYR
                     LRKLLKQESQNDELTNHLRETFEESADELKRELDTWLLGLDVTEEEEK"
BASE COUNT          926 a          625 c          397 g          908 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatcattt cacgcttccg ctcttcattt cattcagttc tcggctttca caatctaaca
      121 cgccgtttcg ctaccagtcg ccttacaggc tccattctcg cttctcttac gtgttttacc
      181 gattgtgccg acaactaaac gaaatgaacg ctaaaacgtc ttagaacgca aaatacacgc
      241 ttataaaatc atttcatctt gattatatgc tcatcataat cgttcaattt gacatcattt
      301 ccgtaaactt tttttatttt tataagcaga aaaaagtcgc acatcaccat tttataaaga
      361 gcataaggaa acgtgtaccc actttctaaa aaaagcgggc agataggctg tgcctatcac
      421 gtttctaaga aaaaaatttg atatcacttt ttcgccattg tgactagctt atgtatagtg
      481 tttcagcaaa aaacagctat acaaatacta tattcgtatg atatacataa attatacaca
      541 aatgcgaaag gagtttttct atggacattt tagttcggaa gattgattca aaggttattg
      601 caaaaataga caaacgttgc caagaactca caaataaaac tggcaaaaaa tggagtcgaa
      661 ataaatatct aaaagtttta atcgaaagtg attttgaccg tcaacttacg acttacaaaa
      721 aagaccaatt cgatttatta ctcgaaaaat ttatcgctat tcagacaaaa aacactcaag
      781 tactaaacga ctatgttcat acaaataatc aacttattga aacacttatt ggaggaaaat
      841 agcatgagaa aaacttctgt tcaaaaacac gttacccttt atcccagtca cgtggacgtt
      901 ttagattcca ttatcgaaag aaatccagat atcaacaatt actcggaagc cattcgtttt
      961 ttatgtatga gttatgaacc tgataccaac acgactacta ccagcaatca agccaaacta
     1021 aatgctatgg gaaaagaaat ttccatcatg tccgaaatca ttgcagaatt tgctgattta
     1081 tatctaaaag atacaggcgt tcttattggc acaaattcta aagtgtatca agaagtgaaa
     1141 gaaaaaaccg aagctaaact aaatccgtcg aatcgaaatc gaccaaagaa tcatcaaaaa
     1201 gaaacgagtc aaacagtcac ttctagaaat ttcgacccaa caaattttct aaaacgctaa
     1261 aaaataaaac gagaattttt ttatttctcg ttttattttt taggaaagcc ggtcttacag
     1321 caagatttgc aagttaccgg taacttgcgg aaaagaagaa gccgctcacg cgacttcttc
     1381 tttttgcatt ttctgaaagc taccacaatt cctaacttcg ctaattatat tctccatgaa
     1441 attcgctcca tgtatcaaaa atcacatctg aaattccatc ttcttcatca aataattgct
     1501 gcattttttt caatttaccc tttctctctg gcgtaatatt tttgtatttt agtaaattct
     1561 catccaacaa atccagcttg accaactgaa tagcactctc caatttttct agattttgat
     1621 aatactcgta tggaaatttc tcagtcattt ttcttcctcc tctgtcacat ctaaacctaa
     1681 aagccatgta tccaattctc tttttaattc gtctgcagac tcctcaaatg tttctcgtaa
     1741 atgattcgtc aattcatcat tttgactttc ttgcttcagc aatttcctta gccgatattt
     1801 caagtcacga ctaatagttg accactcaga atggtcatac aacaacccct ttatcatcac
     1861 tctatccaac gtttttacat cttcaggaaa ataatgcgga ctagcaaaac tatccaaact
     1921 ttcttgaacc atctcatacc aatcagtcgc ttttccacgg cgcaattgta actccaaacg
     1981 ccaccacgtc tcgacttctt taggtacaat ttttcgcttt gcttcctgtt ccaacttctt
     2041 gttgtacatc cgaatttggc gttcgctggc acgactaccc caataagccg tttctagctt
     2101 accagagcgt ccataaattg gtttgaagga cacagggtca actacacgat attgtgtaat
     2161 aaactcatca ggcacatcaa taagatcgca ggcaacatcc gctcgtgaaa aatggggctc
     2221 taaaaataaa tcatgaataa attttttcat agagcttgct aaaaattgac taattttatt
     2281 ggggttaaag tcaatccgcc ctttaccctc ttgccatttc aaaatttcga tataggcaat
     2341 attttcttcg tgttgatcta ccaattgcca accattattc ccaacagctt ttaaatgacc
     2401 attaccttcg ttcactcgca ttaattgctc aaaatctaaa atcaacacat cattttgagt
     2461 gtgataataa atattttcat tcaaagttcc gacaatcgta attcggtcaa tcgaccaatc
     2521 catttttatc atttttacgc tctcaccgac atttaaccgc ctgttagagg gggctgttaa
     2581 tttttcccac tcattcacaa ttgttctttt tttacccaaa ttttgttcct cctcaaagaa
     2641 aaaaagagat ttttggaaag aatttccaga gttcacgtaa ctctaaaaat ccacatccaa
     2701 aaatctctag cttgaagaaa cctaaaaata ttcgtataat gaacttgagt tacggaacta
     2761 ggctagtagt ttccgtaaag gtcgagagtg ttagcgcact gctcgactat ttttttgctc
     2821 ttttttctcg ttttctttga ttatagcact cctctt
//
LOCUS       DADVXB010000195         2849 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.201, whole genome shotgun sequence.
ACCESSION   DADVXB010000195 DADVXB010000000
VERSION     DADVXB010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.201"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(360..926)
                     /locus_tag="KB902_002644"
     CDS             complement(360..926)
                     /locus_tag="KB902_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6809413.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(926..1882)
                     /locus_tag="KB902_002645"
     CDS             complement(926..1882)
                     /locus_tag="KB902_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBB6809414.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1882..2538)
                     /locus_tag="KB902_002646"
     CDS             complement(1882..2538)
                     /locus_tag="KB902_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6809415.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
BASE COUNT          898 a          560 c          512 g          879 t
ORIGIN      
        1 aatttgactg atattaagtt agctattgat atatgaatga catacaaaaa tataaaatct
       61 tttaaaaatg cttatatatc aatgtttttg ccattctttt atatatctgt tatatgtcaa
      121 aaaaatgtgt tcaatttcaa tttgtatttg aataaagagg ttgtgaaaaa gctgtcctgc
      181 atcaagtaat aagaacagcc aatcaaaaac agcttctcat gtttttgatt tggttggact
      241 tattaccgca gatataagct tttgagcacc gtgaataaag aggttatgaa atcaacgctc
      301 taacctgagt attagagaaa aaaacgcaaa acatatcatt tatgttttgc gttttttatt
      361 tatctttttt tctcaataca atataaaata ggcggctggt tcttttggtt gataaaccga
      421 taattcagca cattatatgt ttcctgtggc agtttggaac aaaaagaatc aaccatatcc
      481 agttcttttt ctccaccttc atgaccatag tagacgacaa ggatcaatcg tccgcgaggc
      541 acaagtcgtt tcaatatttc ttccatagct gtgcgtgtag tctctggcat agtgatgatt
      601 gctttatcac tttttgggag ataccctaga ttgaaaatcc ctgctttgag attttgttgt
      661 tcagctatca cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac acgttcttct
      721 aactgacgct gttctagcct ttcacgagta gcatcgattg cttgttgctg gatatcaaaa
      781 ctatagacat gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc gtggccattg
      841 cccatcgttg catctacgac gtgatcccct ggttgcaaga tttcttgcag taatgtatgg
      901 ctgaaatgca aagcagtttg caacatcaga cgctcacctt tttccgtaca tcatattttc
      961 cttggaagct atctctgcga agaagttctt catcaattgc attcaagact tcccattttt
     1021 tcaagctcca cattggtcca atcaaggaat cccacggcgc atcccctgtc aaacgatgga
     1081 tgatgatctc ttttggtatc atttccagct ggtcgcaaat gacattgaca tagtcaggac
     1141 ggctcattaa ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt ttgcgcatca
     1201 gatgcatcaa atggagcttg attccttgga tatctgaatc taaaatggtg cgtctgacat
     1261 tttctttcat catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc gtacaaacac
     1321 ggatattatg tttgcgtaat ttagccacgc catctaaata agtttgataa tcatgtgctc
     1381 ggttgatcag ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct acccataaat
     1441 acatccgctc gttcagttca gcaaggtaat caactacttc atctggcaga caatccggtc
     1501 gtgtaccgac tgataatcct acgacacctg gtaaattgac tacttgctca aatcgttctt
     1561 tgattatttc aactggcgca tgggtgtttg taaaattttg gaaataaacg atgtattgtt
     1621 ggacatgagg ccatttttga tgcatcatgt cgatttcttt ctggaattgg attggaagag
     1681 ggtcttcagg tgcaacgatc atgtctcccg aaccagatac actgcaaaaa gtacaaccgc
     1741 catgggcaac agtcccatct cgattcggac agtcaaatcc tccatcgatc ggcaccttga
     1801 aaattttccc gccaaactca tttcgtaaag cgtaattcca agaatgatat cttttatttc
     1861 cttctgaata aggaaaagtc attaaaagtc cttctttctg taagagttat ctatttgttt
     1921 tcttttttct ctatacactg gataagtcag gcacagccaa gaaagactga gtaagtagcc
     1981 gccgatgata tcagtaggaa aatgaacgcc cagataaatg cggcttatcc cgacacttac
     2041 tataataaac atcatcagca attgaagcaa tgtgcgtaag gttctttttt gaacaaaagc
     2101 tggaagcaga aatagtaaag aaccgtaaag aatcatactg cctgctgcat gtccactagg
     2161 gaaactgtaa cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc gcatgaaaaa
     2221 tagtttgatc accgggttga tgattccagc aattacaata aatccagaaa cgaaccaaaa
     2281 tgtttctgcc ctttttttct tataccacat ccataaagcc gcacaagcaa ataaaatgat
     2341 gacggtaaga ggattaccga atttagtcat aaagagttgg tagctgttca gatcaggata
     2401 agaagctctg acaatgcctg taaaccactg atcgaaacca gaaagccacg acagatggaa
     2461 ctttacgatc cagcccaaaa tgaaaaacag gacaagaaag aagctaccag ccacctgaaa
     2521 tgatgtttta tatttcatac aattcctcct ttgaagcaat gacttattat agcatttttg
     2581 gtccagcgaa aaaaacggta aagagataaa accaatgtat gattcctctt tgaataacca
     2641 atattcttat aaaaaaaata actgtaatcg gaaagacatt ttttggtaat gcaaatgaaa
     2701 tgttagggaa ataaaatcag tgtttttcga aatcctttta aacaagaacg tagacgtagg
     2761 aagaacttga aaatgaacag aagttgttca ttacggtaaa ttacaatatg attacaaaaa
     2821 acaacaaagc tcttaaataa cttttaata
//
LOCUS       DADVXB010000196         2630 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.202, whole genome shotgun sequence.
ACCESSION   DADVXB010000196 DADVXB010000000
VERSION     DADVXB010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.202"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            660..997
                     /locus_tag="KB902_002647"
                     /pseudo
     CDS             660..997
                     /locus_tag="KB902_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328881.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            997..2120
                     /locus_tag="KB902_002648"
                     /pseudo
     CDS             997..2120
                     /locus_tag="KB902_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343089.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(2271..2630)
                     /locus_tag="KB902_002649"
                     /pseudo
     CDS             complement(2271..2630)
                     /locus_tag="KB902_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332307.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          936 a          406 c          503 g          785 t
ORIGIN      
        1 ttagaaaaaa ggttgattat caaagaaatt gactaataac atatgatata attgataggt
       61 agaaaagtga aaagatggtg gctaatctct taaaaagggg tgatgcctat ggttcatagc
      121 tttatcccta gaagggagta agcaagtgtc aacttttgaa gcaattcaac tgatgatcgc
      181 ctttgcgacg ttagttttgc tgattcttga ccataaagac ccaaaaaaat aaccatctaa
      241 acactttggc taggagttag atggttaaaa aactataaac ctatgtcacc gtctttttaa
      301 cggttctaca ctggagctat gttagagcat agctcctttt tgttgtctta agtatagcaa
      361 agtaaaggga aagttgcaaa tacggtgaag ttttacaaat gttgtgaagt cctacttgtc
      421 atttttctag ataaatggca taaattttca gcgctaagtg acaaaagcaa ctaatttttc
      481 atgatagatt tttaaatatc tcaatctatc tccaaaatta gttgcttttg tagctatagt
      541 tgactatgaa tatgacaaat aattagaaaa aactgtgcca attaaatatc aaaatgacaa
      601 attgatgaat caaattcaaa ttaagggggg caaccctgga agtcttaaat ttaccctcaa
      661 tgaatggtat tgaagatgaa aatttaaggc gtttgattaa tagccttgtc attgaattgt
      721 acaagtatca agcagaatca gaacgaaaaa aattaaggaa cgtcaggcat aaggaatcga
      781 aattgctaag aaaaaaggca aattcaaagg tcggcaactg aaatttaaaa aaaatgatcc
      841 acgtttaaag catgctttcg atttgttttt gaatggttta tccgataaag aagttgaaga
      901 acaaactgga atcaatcgcc gaacgtttag aaggtatcga gcaagatata acgtgacagt
      961 agatcaaaga aaaaacaatg aaaagaggga tagttaatga gtacggttat tttagctgaa
     1021 aaaccaagcc aggcattagc ctacgcaagt gctttaaaac aaagcaccaa aaaagacggt
     1081 tattttgaga tcaaagaccc actatttaca gatgaaacgt ttatcacctt tggttttggg
     1141 catttagtgg aattagcaga accaggtcat tatgacgaaa agtggcaaaa ttggaaactt
     1201 gaatctttgc cgatttttcc tgatcgatac gattttgaag ttgcaaaaga taagggaaag
     1261 cagtttaaaa ttgttgcaga acttctcaaa aaggcaaata caattattgt tgcaacagat
     1321 agcgacagag aaggtgaaaa tatcgcctgg tcgattatcc ataaagcaaa tgccttttca
     1381 aaagataaaa catttaaaag actatggatc aatagcttag aaaaagatgt gatccgaagc
     1441 ggttttcaaa atttgcaacc aggaatgaat tactatccct tttatcaaga agcgcaaaca
     1501 cgccaaattg ccgattggtt gatcggcatg aacgcaagcc ctttgtatac gttaaattta
     1561 caacagaagg gcgtacaagg tacattttca ctaggacgtg ttcaaacgcc caccttatac
     1621 cttatttttc agcgccagga agccatagag aattttaaaa aagaaccttt tttcgaggtg
     1681 gaagctagta taaaagtaaa acaagggtca tttaagggcg ttctaagccc cacacagcgt
     1741 tttaaaaccc atgaggagct ttttttgttt cttctaaaca agctaaaata ggcaatcaag
     1801 aggggataat tgctgatgtt caaaccaaag agaagaaaac gaatagtccg agtttgtttt
     1861 ctttaagtag tttgcaatca aaagtcaatc agctttataa agcgacagcg agccaaactt
     1921 taaaagctat gcaaggactg tatgaagcaa aattattgag ttatccaaga acagatacac
     1981 catttattac agagaacgaa tttgcttatt taaaagcgaa ttttggcaaa tatagcggtt
     2041 ttttaggact tgatcttgaa atgttgttat cattgataat gatacgttca aacaacagca
     2101 cccaaatttt gacgaattag tgaaactcta tgaaaaagac gtagtaaaac atgcaacatc
     2161 ctattctaat cagctggtaa agcttaatta ggttatataa gcttgaaaat aaagggtttg
     2221 tccaatatgg acaagccttt ttcttatgtt ttgccacaga tttgccacac ttattgtgta
     2281 agagtatcaa ggataggtat aatttgatcc tttgtttttt tagtgatgtg caaataaaat
     2341 ttctgttaca cgactacctc tagaatgccc tacacggtct tgaattgctt ctaggggtat
     2401 tccttgctct gctaagaaac taatatgcgt atgacggaat atatgggtcg taatatgttt
     2461 attaaaacta agtttattat caatatcaat tcctgctcgt tttggattac cttttcgatt
     2521 taattttcca ttttcaggtg agttgaggaa attgttaagg acactataat gaagaggtgt
     2581 tccattatag tcgggtttat gacgactttt ggaagtaaaa atccatccat
//
LOCUS       DADVXB010000197         2574 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.203, whole genome shotgun sequence.
ACCESSION   DADVXB010000197 DADVXB010000000
VERSION     DADVXB010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.203"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(166..1218)
                     /locus_tag="KB902_002650"
     CDS             complement(166..1218)
                     /locus_tag="KB902_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6809416.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(1231..2169)
                     /locus_tag="KB902_002651"
     CDS             complement(1231..2169)
                     /locus_tag="KB902_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6809417.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
BASE COUNT          842 a          554 c          396 g          782 t
ORIGIN      
        1 attgacaaag agccagtttc ttctacattt taaaaaatcg aatggcactg aagagttcag
       61 ttgtcagcat caatctccta ctcaaaaagg caaaaaaacg taagtcagat gttgttgaca
      121 tctcacttac gcatccattg attgaaaatt tcttagtaaa atctactagc ctaaaaattt
      181 gaagacttct tctcgatcat acagtttaaa tactttctcg cataaaaatt gagtaattag
      241 tgccgcaaaa acagggatga ctaaccaaca aagaacaaca agaaagccat ttagccctgc
      301 atctaaagaa gccaacggac caacaagtcc gaccacgccg aaaccagcag aagcaggcgt
      361 acctgaaata gaaaatagag cgacaggaat agctgtaatc actgcactaa ctaaacaagg
      421 aataagaatc acaggttttc taaatagatt aggcatcatc atcttcatag cgcctaaagc
      481 aatcgcaatt gtcacacctg acttattaac cttccaagag ttcactacta aaacaaaagt
      541 ggttgcagct acgcccatcg cagccgcacc agcagaaaca ccatctagtt ggattgccat
      601 tccgattgct actgttgaaa taggagagat aatcaaaaag gcaaaggaac aaccaatcaa
      661 gatagacatt aacagcggtt gtaaggtagt gaagttatta atcaatgatc caattgcaga
      721 agtaattgct gttacaaaag ggaataaata aaaaccaagt aaacctgcac ctacacctac
      781 aacaatcggt gttaacacaa tcgacactga cccaaaacta tttccaatca gtaaaatcag
      841 cccgacagca atcgatgctg tcagcatcgt attaataata tcgcctgtac cagcaccaac
      901 gtaaacaccc gtttcaccca aatcaggtgt gaatttgact acaccagaac caacaaaaga
      961 agctccggct acaaccatca ttctcatcgg atcaaatcca aattgtaagg caatcaaacc
     1021 accaatgatc aaaggtgttg ctagttgaaa aataactgct aactgtgcga tcgttaccgc
     1081 aaagggatac gcactaaaat attttaaaat ggcacctaat actgcattag gaatcaatcc
     1141 aataatgatt cctgttgctg taccagcgag gactttattc agaaaaattt tcggtgatat
     1201 tttttgtgaa gtttccattc aatctctcct ttattttacg ttcaaactat cttcttttgc
     1261 atggacaagc tcagtcaaga aatcacaata aggcgtcgca acaccatatt tcttcccttt
     1321 tctagaaatt gcgccattga tataatcgat ttctgttaat cgatggttct taatcaagtc
     1381 ttgatacatt gaaggataat gtaacccaat tgtttccggg tcaaaacaag attcacaatg
     1441 tgcaatgact tctgggacat ctagttcaat cttctctact gctgctactt tggcaaactc
     1501 attgacaatc gtcgccacca ttttatgagc agtcgatgtt tttcctagct cagccatatt
     1561 aacgtctaag attgtgcata gtccgttcat tgttccgttc acacatgctt tgcgataaat
     1621 agaatagtga atattgtcag aaaaatgagc atttaatcct gattcagaca atttgtctgc
     1681 taattttttt gcagctgctt cttttccatc acctaaattt tgtaattcta ctgaaccact
     1741 tccaaataat ttgacctgac caggaccttc aagacctgcc gtccacatgg tatttccaat
     1801 atagatattt tccattggta caaatttctc aataatatct tcatgcccga taccatttaa
     1861 tagacataag acctctgtat cttttttgat taatgattgg atatcctgca gcattttttc
     1921 cagctgcatc gctttggtaa atagaataat cagatcaact tgatcttctt tttctacttc
     1981 ggattgaaga acgattggta gttttgcttc tacctcttta ccattaaaat ttgcttgtaa
     2041 tccatgttct ttgatttgtt ggacatgttc tgcccagcca tcgattaata atacttcgtt
     2101 cccactttgg tgaagcatca acccaaagcg acttcccatt gcgccagcgc ctgcaattgc
     2161 tattttcatt gattcttcct cctttttctt tctattatac tcatttgaga atcttttcac
     2221 aacctcgttt tgttattctt ctcttattta tcatgtttat atccaccatt caagttattt
     2281 tatcagcaaa tcaataaaaa ctggaataga atcccaattt catcgtaaga gaaactagac
     2341 tagcaataag aaaatagaaa cattcataga aaaaatctca ctcctctgat tataaaagag
     2401 ggggcattaa cctcgtgtat actaaaacct tccattcatt cgatggatga ttttcttttt
     2461 gtgaaaaaat attcattgta gtacgatgtt gcgcaacaca gacggatggt attgcttatt
     2521 atttattaaa atcgaacaat acacttattt aaaaacttct ttcccagatt ttct
//
LOCUS       DADVXB010000198         2524 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.205, whole genome shotgun sequence.
ACCESSION   DADVXB010000198 DADVXB010000000
VERSION     DADVXB010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.205"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            237..2390
                     /locus_tag="KB902_002652"
     CDS             237..2390
                     /locus_tag="KB902_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBB6809418.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFAPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKALELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYTPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTAAKPLASAKMDLSAKTGTAETVAEGHPDITTVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHMNLTIAKEIMDAYYDMFMAK"
BASE COUNT          870 a          435 c          548 g          671 t
ORIGIN      
        1 ataaatgatc catcaaagtg tttcacgact taagaaaaca taattttcaa aaataagttt
       61 attttttaat gaaaaaaata gttggatatg taactttaag tgattgctgt gaaacaaaaa
      121 gttgatttta tcttgaaatt aggtaaagaa tttcttgctc cgcccatttt ttctttttta
      181 ttaagaagtt tttgggtaca atgaagcatg aatgtaaata ggcggaagga taggaaatga
      241 tgaaagattt tatgaaaaaa atattaaata cttcttggtt agaaaaaata agaaaaggtg
      301 cacaagaacc taagaacaaa acgtttcgcc ggtcccatgt tccttttcgc ttaaattttc
      361 tttttttcat tatatttacg ttatttgttg cgttgattgc tagattgggt tatttgcaga
      421 tcgtgaacgg cgaagagatg gaggcgcgag tgaagtctac ttctacgatt acggtccaag
      481 aaagtactcc tcgcggaatg atctacgact ccacaggaaa agctttagtt acgaataaag
      541 cgaatcaggc catcacatat acgagaggaa cacaagttac ggctaaagat ttgcttgaaa
      601 tcgcaacgaa gctgaactcg ctgatcgatg ttccggtaga tgaaaatctg acagatagag
      661 ataaaaaaga tttttggctg gctgatccca aacatttgaa agaagccaca aaaagacttt
      721 cggcaaaaga aaagcaatta gggaacagcg aacaatatag tgcgatggtc aataaagtca
      781 cagctgatga gattaattta aacgaggagc aattaaaaat tgctaccatc tttaaacgga
      841 tgaatagtgc atatgaatta aacactgtct atatcaaaaa ctctggtgtt actgatcaag
      901 agttagctgt tgtggcagaa cgcgcttctg aacttccagg agtttcgact ggcacagact
      961 ggacacgaga atataatgca gcaagttcac tgaaaagtat tcttggcagt gtgacgactg
     1021 aaaagcaagg acttccagca gatgaagcag agaaatacct agcaaaaggt tattctcgga
     1081 atgaccgtgt aggacaaagt tatttggaaa aacaatatga agatgtcctg caaggaacca
     1141 aaacccaata tgaagtttcc cttgataatg aaggaaatgt ttcgaatcaa aaagaaatct
     1201 tctctgggga aaaaggttct aatttaatgt tatctatgaa tgcagaattc caatcaaaag
     1261 tagaagaaat tttgaaaagg aattatcaaa cattgatcaa caacggcaaa gcacagtatt
     1321 cgcctggtgc ttatgcagtg gctatgaatc ctcagacagg agaagtgcta gcaatgactg
     1381 gtttcagtca tgaacaaggt tccaaagaaa tcaccgagaa tgctttaggc acgattacta
     1441 gcgcctttgc tccagggtct gtagtcaagg ctggtacttt gacagcaggc tgggcaagta
     1501 acgcgatcag cggaaatcaa gttttgattg atgagccgat tcgtctgcaa ggtgcttcag
     1561 aaaaaagctc tgtctttaat cgaagcggac aagttgctct tgatgcagtc aaagcattgg
     1621 aattgtcttc taatacgtat atgatcaaag tggcgttaaa gatgttagga ctagactata
     1681 cacctggaat gggactacct agtttagatg aagaagctaa agcttatcag caattgagag
     1741 actctttcaa agagtttggt cttggtacaa cgactgggat cgatttgccg aatgaatctc
     1801 ctgggatctc acgttctgtt gattatatga agaagttcaa tgcggataat ggcaaagaat
     1861 ggtatactcc aggtaacttt accgatttgg catttggaca gtttgacaca tatacaccaa
     1921 tccaattagc tcaatatgct tcaacagtcg ctaatggcgg gaaacgagta cagccgcacc
     1981 tagtcaaagc gatctatggc aatgacgaaa atggaaactt gggtgaagtg aagaaagaaa
     2041 ttggcacaac agtagaaaat acggtcaata tttctgcaga aaatatggcg atcctccgtg
     2101 aaggattcca ccaagttgtc catggtaccg atccttacac agcagccaaa ccattagcca
     2161 gtgcgaaaat ggacctttcc gcaaaaacag ggactgcaga aacggttgcg gaaggtcatc
     2221 cagatattac gacagtcaat agtaatatcg tggcatacgg accaacagac aatccggaaa
     2281 ttgccatcag tgttgtcttg ccgaacttat tagacgaaca agaccacatg aacttgacga
     2341 ttgctaaaga aataatggac gcgtattatg atatgttcat ggcaaaataa aaaagaggtc
     2401 gtgaaaaagc cgcttagttt cgagtatgaa gaaaaatttt gtgaaaatag cttctcacat
     2461 ttttgcttaa atttgacttc ataccgagaa actggctttt gaacaccgtt tactcggcaa
     2521 aaaa
//
LOCUS       DADVXB010000199         2438 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.206, whole genome shotgun sequence.
ACCESSION   DADVXB010000199 DADVXB010000000
VERSION     DADVXB010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.206"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            316..570
                     /locus_tag="KB902_002653"
     CDS             316..570
                     /locus_tag="KB902_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6809419.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="KB902_002654"
     CDS             571..888
                     /locus_tag="KB902_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6809420.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="KB902_002655"
     CDS             1447..2382
                     /locus_tag="KB902_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809421.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          884 a          345 c          458 g          751 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagagaaaaa
     2401 tgtctaaaca tgttggtaaa tcaacaaaaa aacgcata
//
LOCUS       DADVXB010000200         2422 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.207, whole genome shotgun sequence.
ACCESSION   DADVXB010000200 DADVXB010000000
VERSION     DADVXB010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.207"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            21..1199
                     /locus_tag="KB902_002656"
     CDS             21..1199
                     /locus_tag="KB902_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBB6809422.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIE
                     SFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
                     "
     gene            1279..1539
                     /locus_tag="KB902_002657"
     CDS             1279..1539
                     /locus_tag="KB902_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809423.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1901..2140)
                     /locus_tag="KB902_002658"
     CDS             complement(1901..2140)
                     /locus_tag="KB902_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809424.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          872 a          397 c          426 g          727 t
ORIGIN      
        1 acagaaaaga ggacttccct atgaatgatt ttactacaga aattgtgcaa actctagtca
       61 ctaaaggcga tttaaatgaa ttattccgtt cgcacttaga aaaagcgata aacacactcc
      121 tacggactga attaacggct tttttagatt acgaaaaata tgatcgcact ggttttaatt
      181 caggtaattc gagaaacggt tcttactttc gatcaatcaa aaccgaatat ggtgaattaa
      241 cattggaaat acctagagat cgtaatggtg agtttaaaca acaaacttta ccagcctaca
      301 aaagaacaaa cgatacattg gaaaccacta ttatccattt attcgaaaaa ggtgttacga
      361 tgtctgaaat tgctgatttg atcgaaaaaa tgtacggtca tcactatact ccacaaacca
      421 tgtccaacat gactaaagtt ctgactgaag aagtaaatgc ctttaaatcc agagccttaa
      481 atgataagta tgtcgctatt tttatggacg ctacttacat tccactaaaa cgtcaaaccg
      541 tatccaaaga agcgatttat attgccattg gtatacgaga agacggcact aaagaagtac
      601 tgagttatgc gattgctcca actgaatcaa catacgtttg gaatgagctg ctacaggata
      661 ttaactccag aggagttcaa gaagtcttgc tttttattac ggacggctta aaaggcatga
      721 aagatactat ccatcaaatt tatcctaaag caaaatatca gcattgttgt atccatgtat
      781 ctcgtaacat cgctcataaa gtacgtgtca aagaccgaaa agaaatctgt gatgacttta
      841 aggctgttta tcaagctaac tcaaaagaag aagcgaatac cttcttatcc ggcatgattg
      901 agaaatggaa gaaaaactat cctaaagtga cgcagtcact catagaaaac caagacttat
      961 taacttttta tgattttcca cctagcattc gtagaaccat ttactcaacc aatctaatcg
     1021 agtctttcaa taagcaaatt aaaagataca gccgtagaaa agagcagttt caaaatgaag
     1081 aatcactaga acgctttcta gtcagcattt ttgatacata caatcaaaaa tttctaaaca
     1141 gaagccataa aggttttcaa caggtaaccg atacattagt ttcaatgttt actgagtaac
     1201 taattatttt gcaggaggac aatttattta cacaaaatta ttgacgctcc ctggaaaaac
     1261 attaaggatg gatgaaatat gaataacgaa actatcattt taggaaaaaa atatatttgc
     1321 caacctattg gcttgaaaca aaaagtggtt ggagaagtaa tcagtaaatt agaaaattgt
     1381 gttgtgatct gcgtagacga atatcatgac gtcgatcgca atgaaatatt agaaaaatgc
     1441 ggaaaagtag tggcaaaata tactcacgtt tatgagttgg aaacaacaga atatctatat
     1501 aactatagca acaaatatga acatacttta gtttcataaa gatttaaata aagtgccttc
     1561 aaaagcgaga agaccaagct tttgaaggca ctttatttag ttggcagtga ttgttcatga
     1621 tttttgattt attcaaaagg ttcgcctaga gaatctgtct ctgtaacgag gcctggtgga
     1681 gaaactcgat aaaaacctat actgccagaa ctgtcctatt ttcggataga caaactagta
     1741 gttttaaaaa gatcatccga tccaatcatt tcaaaaaatg caaaactgat atcaggatca
     1801 tttagctcag gcttgttatc gtaaagcatt tgtaaaggtt gcatttagtt aggagtaaac
     1861 gcgaaactat catcattatt tgctgaagaa gatgaagaag ctaattcaga gtttgtttga
     1921 aataaaggag acgtgctgac agtttcttta ccctgttttt tgcagaggta gaaactttta
     1981 tatcggaagt ttctaccgga gaatttttct catttgtaga aattgttgaa tcgatactat
     2041 tcgaaatttg cgtatctgaa ggtatgttct ttgatgcaga agtcccacaa gcagtaagta
     2101 acaataaatt tgataaactg ataaacagaa ttcttttcat tatgtacaca ctccttatag
     2161 tatcgtttag catacaccta tgctcagtat taggcaaaat caatgcaaaa ctatcaagtc
     2221 ttttatagta tctattagtc ttagtaatac atatatggag agggtgatat cccagttcaa
     2281 accagataca ttggttacca tctgtattaa cgattatgcc tctaaacgct ttttttatga
     2341 aaaaatttat aagtgaaaac gtaggtatga tattatctag aggtaatttt tttgggtatt
     2401 taaatagttg ctaggaggat ag
//
LOCUS       DADVXB010000201         2403 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.208, whole genome shotgun sequence.
ACCESSION   DADVXB010000201 DADVXB010000000
VERSION     DADVXB010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.208"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            16..201
                     /locus_tag="KB902_002659"
     CDS             16..201
                     /locus_tag="KB902_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809425.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            213..461
                     /locus_tag="KB902_002660"
     CDS             213..461
                     /locus_tag="KB902_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809426.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            492..671
                     /locus_tag="KB902_002661"
     CDS             492..671
                     /locus_tag="KB902_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809427.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(714..1184)
                     /locus_tag="KB902_002662"
     CDS             complement(714..1184)
                     /locus_tag="KB902_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809428.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            1271..1969
                     /locus_tag="KB902_002663"
     CDS             1271..1969
                     /locus_tag="KB902_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6809429.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            2147..>2403
                     /locus_tag="KB902_002664"
     CDS             2147..>2403
                     /locus_tag="KB902_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809430.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEE"
BASE COUNT          889 a          346 c          483 g          685 t
ORIGIN      
        1 aaaggagcta tttttatgtc tgagaattta gacttaaaaa ttcgagcgga gatgagaaaa
       61 agaagaatga ctttcaaaga actagctgcg cttatcggta tttcaggagc ttatttatca
      121 gatattctaa acggcaatcg tgatggaaag aaagcacaac agcatatcga aacagtgaaa
      181 aaaatattgg acatccgata ggggggtagg cgatgacaaa actaaaaaaa caagattttg
      241 taaaaaaata caattattct ccatctactt atcaacgtcg aatgtcggaa ctaaaaaata
      301 cagcaatttt ctcagcggcg tatgaacggg tcacaggaca agaagtttgg atcaatacag
      361 aattatacga taaatttttg tctttcaaat cctataacag gttacgcaca agaaaggtaa
      421 cacctaaaga atttatcgag aagcatttag ttgatttata aaaaacagaa cattttgaga
      481 ggtgaaggtt aatgggtaaa ttcaacagag cattggtatt cagcgcaccg ctaatcatct
      541 acgctttagg actttgggga agcaggcaag cgttgatagg aacgattgtt tacatggttt
      601 ggatttttat ggggcttgat gaagctgaag ctgagtacag agcgaaaaag ccaaccgagg
      661 gggctgacta aaaatgaata gaaaagagaa actagaatgt atattactat tactcagttt
      721 aattctttca ctaatttctc tattgggaag tttgtatttt tgatatcaac aattttgtgg
      781 atttgggttc tatttagagt aaatatcatt tttgtttggt gattaaggag tttattaaaa
      841 ttaattttcc ctacttcaaa tgcaaggtaa caagatatag cacttttagg aggaatattt
      901 agcggtacag cttcagagta tattctatta tcatcgactg atcctccttt agcaattaat
      961 ttcttaaatg gagtagctga ccatctgcgg tttaagttag cggatgaaag ttctaaatta
     1021 actaacatag ctggttctgt tgaatagtta gaaatgatta cttttgtata aatcatatct
     1081 gcagcgaagt aagaagcatt aagttcaact tctagttgag ggcgcattcc ttttattttt
     1141 atccctgtta aaaacgtact caatataaaa cttattattg acatccattg aaaaattgtt
     1201 aagtgaaaaa aattcaaaat aaacaccacc agtttttaac taaattatac caaaaaggag
     1261 agaagaaata atgcaagaat tagtaatttt gaaaaataaa gaagctgtga ctacgagctt
     1321 acaagtggca gaaagcttcg agaaaaaaca tcaacatgtt ttaagagata ttgatgcact
     1381 aaaaaaagat gtgtccaatt ttggacagat gtttgtagaa ggtaatgaac cagattcata
     1441 tggcagaaat cgacgagttt tcttcattag tagagatgga tttttcttgc tggctatggg
     1501 gtttacagga aagaaagcta tctacttcaa acaaaaatac attgaagcat tcaacgaaat
     1561 ggaagatgtt attcgcaaga atactgttcc tcaaacaatt gaagatatga tgatctatca
     1621 attagaagaa atgaaagatg ttaaaaaaga tgtttccatg cttaaagata ctatgcgaat
     1681 tagcggacaa caagagtttg aaattaagca aaaaggaaat atgaaagtta tgggagttct
     1741 agggggaaaa gaaagccgag cttatgaaga aatcagcaaa aaagtattct caaaattttg
     1801 gtctgaattt aaacgtacct tttcaatccc aagatatggc gagttacctc gtaagagatt
     1861 cgatgatgct gtttcattta ttgaaatgtg gttgccagaa actgcgatcc gtatggaaat
     1921 tgatcaactg aacagacaac agagactttt tggtgatgac aatgaataga gctgaagcgc
     1981 taagaatagg gacggcaatt gctaattgct ggtggaaata ctataaacca atcatcctaa
     2041 gccaacaaca tattgacaag caaaaagcat ggcaacaaat aaaaaagtga ctccgccggc
     2101 aagcaaagag tcacaaagaa aacacatcat aaggagattt tagcatatgg aaaaagaact
     2161 ttccactcta gatcaatatt tgattgatcc tgattggggt aagccgaaaa ttgaggaaac
     2221 aagtggtcga aaaatcagac gaaatctttt gacgaatgaa gaactagctt gggatcaaga
     2281 tgatttaggc aaccatgtaa ctatttggga tcatgtttat cttatccatc tatcgaagca
     2341 ttcgaataaa cctgaatata tttacgtcat cgaagatggc ttgattgatg cgctagaaga
     2401 gta
//
LOCUS       DADVXB010000202         2399 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.209, whole genome shotgun sequence.
ACCESSION   DADVXB010000202 DADVXB010000000
VERSION     DADVXB010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.209"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            208..2070
                     /locus_tag="KB902_002665"
     CDS             208..2070
                     /locus_tag="KB902_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809431.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2070..>2399
                     /locus_tag="KB902_002666"
     CDS             2070..>2399
                     /locus_tag="KB902_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809432.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaaatttg aaaaagcgtt tgattattta tattacgact tagtgcaata aaaaacgctt
       61 tttaacagta catgtagtcg tctttataat agataaactc tgtaatatta gttaaaaagc
      121 tataagttgc acttagttaa gtgcaaacat ttcatattgt cgttagttta gaaaacgctt
      181 atattagcaa tgtaaggaga gatgataatg cagcagctaa caaaaagaga aaggcagctt
      241 ttgatttact tggtggaaat gtctgaaccg gtaacaatca aaaagttggc tgaaaaagaa
      301 aatgttagtg ttcggacgat aaaatacgat ctagatgata taagagagtg gctgaatgag
      361 cggaagcaag tcctatatag caaacgtagt cagggaattt ggatgaatat tagtagctct
      421 gatcgaatca aattaaaaag cgaattgatg gatgttaatc gttttgaaat atttgcagat
      481 caaagtctcc gaatcaaacg tttactaatt atgcttttag taacaaaaga agctattact
      541 ggaatgaaaa tggccaacgc attagatgtc agcaaagata cgatcatgaa tgatttagat
      601 gtgctggaaa ataattttct taaggaagga ttgaccttga atcgtcaggc gcgaaagggt
      661 ttttggatca taggagaaga acgtctagtt cgattaacga ttgaagagat tcttcaaaaa
      721 gagttcacgg attatgacat ttataaatta atgtcattgt tattgaatgg cggtgagact
      781 gaatactttg aaatgtattc tgctactgct acacctatcc aagaggtatt taatcaagta
      841 atcattcgaa tgcgacactt actggaattt gaaaatctag agaaactgaa ttacgcggaa
      901 ttactaaata ttctgattcg agtgacaatt gctaccgttc gcttacgcaa agaggctacg
      961 attggtcgtt atcaattggt tgctgaacaa gaattagaca aaaacgatct ttcttatcgc
     1021 gtcatgcagc aggtctttga ttattatcag ttgccactgt tcgaggatga atatcattat
     1081 atctatagtg atacattcga cacgattcac cagcaagacg tcatgaaact agttgagaat
     1141 gtgatttata aagtaagtaa agcaatcaac cattcttttt atcaagatcc acaattgttg
     1201 acgaatctgt atgctcattt atccatgcga ttatcgagaa agaaaaaatt tgtcaatgaa
     1261 tataatcctt ttaaagaaga tatcaagcag aaatacccgg aattatttga tgcgatcaag
     1321 caagcagttc gacaagaaat aagtgaacaa aatattctga tcaatgattc tttcgtggca
     1381 tatattgcct tacacttttt ggtttcctac gaaagagaag aagatctacg aagcgttaga
     1441 gccgtctaca tttgttcaac agggttgggt gtgactagtc tgatcaagca aaagatcaat
     1501 gaagaattaa ataatatcac tatcgtggca tttgcttcag tattgaatgc gcaagaaatg
     1561 attgctacca aagatcctga tttggtgatt agtatttttc caattaatgg catcgatcgt
     1621 cctttcatca aagtccatcc attacccact gaacaggact tgaaaaaaat tcaacaaata
     1681 ataaaaaaaa tacttgcttc ttccaatcag caggaaaggc ataacttgaa tcttagagaa
     1741 acgtccatca ataaagatac tttagaagac tttagcaagg aattgatttt gaaagcttat
     1801 acgatttatg aacgtttact tgtcattttg gaagcagaat tgatccaaga atatcgagaa
     1861 gcttttttgc ttcatgtatt cttaatggtt catcgtatca catttgatca acaatatatg
     1921 gcagaaggtc gtcaagtaga ccagattatt ttagacaaag gaacactggt aggaaaaatc
     1981 gaagcagttt ttgcagaaaa taatttagga atcaatcagt cagaaatcag tgcattattc
     2041 tcatatataa aagaaggagc gtcaagttag tgaaaatgtc agacgaggct ttaaaaatta
     2101 tcgaggaaag tcaaaatcgg gaaaagttaa aacaagtgat tgatctaatt gaagagcgat
     2161 tagtagaaca tgctattgta ccaaccgagt tgcagtggac cattctaatt aatcacttga
     2221 atgagatgct gaaacgttct caaagaaagg aaacgattcc cgtagtcgat cgggatttgt
     2281 tcaaagaagt atccaaagaa gccataacta tttctgatga aatagttaga agtatcggta
     2341 atttaaccga tgatgaaata tatgttttgt cgattcattt tgaaacagca aaaaataat
//
LOCUS       DADVXB010000203         2388 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.210, whole genome shotgun sequence.
ACCESSION   DADVXB010000203 DADVXB010000000
VERSION     DADVXB010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.210"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(5..250)
                     /locus_tag="KB902_002667"
     CDS             complement(5..250)
                     /locus_tag="KB902_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809433.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(267..1118)
                     /locus_tag="KB902_002668"
     CDS             complement(267..1118)
                     /locus_tag="KB902_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6809434.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            1284..2288
                     /locus_tag="KB902_002669"
     CDS             1284..2288
                     /locus_tag="KB902_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBB6809435.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT          762 a          404 c          482 g          740 t
ORIGIN      
        1 ctttctattt tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat
       61 gttcgtgcca gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga
      121 tttgatcatg tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa
      181 agacaaaatc ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga
      241 ttggatccat aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg
      301 ccgactacac catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca
      361 aataattcag tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat
      421 tcgtgttgca gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg
      481 atttgtttca tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg
      541 aggatcatat catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca
      601 aggaaaactt gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg
      661 tggggtaaga aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca
      721 aatgctcgcc atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt
      781 ggccagtgga tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca
      841 aaagaagaca tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat
      901 atctcttctc taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg
      961 tatccttggg cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa
     1021 acagcgacat ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa
     1081 ccatttgata gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc
     1141 gttcaactat aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg
     1201 aaatttttgt ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa
     1261 ctaagacaga agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta
     1321 ttgacagaga aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat
     1381 atattcgtga ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg
     1441 gacaactagc agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg
     1501 tggaagcaag tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag
     1561 cacctagtgc agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt
     1621 tattgaaagt caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga
     1681 tcgacaaccg cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg
     1741 aagcattcgc tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt
     1801 tttctggcaa aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt
     1861 ctttagaaga aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg
     1921 agacagaaga atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag
     1981 aaaaaggtcg gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg
     2041 caaaaatggc ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg
     2101 taaaagaagt acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa
     2161 acgggatcga actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg
     2221 tgaataatcc ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc
     2281 gtttataaaa atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg
     2341 tgtcaagaga aggatcggaa aagacgaata taacaaaaaa agagcgtg
//
LOCUS       DADVXB010000204         2350 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.211, whole genome shotgun sequence.
ACCESSION   DADVXB010000204 DADVXB010000000
VERSION     DADVXB010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.211"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(94..2193)
                     /locus_tag="KB902_002670"
     CDS             complement(94..2193)
                     /locus_tag="KB902_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6809436.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT          472 a          475 c          408 g          995 t
ORIGIN      
        1 aaaaaggagt atgacaacag ttgtgtcata ctcccctttt tcgaataaac ggtgttaaac
       61 ggcaggctca cagcctcttt catttgccta aaattaattg ctcccatttc ctccgaacca
      121 tccagtttta cagttgatgg ttacgatgta aaatggcaaa gcactttctc caatgccttt
      181 catcaatgca gattttgttg aagtggcata tagattataa tagccttccc cattttcgat
      241 tctggctttt tctaatctgt aacctccttc aacgatatat ccacgttgga tacatgtagc
      301 aatcactttg ctttggacac ctggtgccca cgtccatgct ggattagatg catcggcaat
      361 atcacttgct ctggcagatt tgattggctg attcgctgag tttgaagagg aaggggtcga
      421 ggatgccgct tcttgctgtg ctgcttgtgc gaccgcagct tgttgagcgg cttgagctgc
      481 agctgctgct tgagcggctt gttttgcttg ttcttcagct gcttttttcg cttcttctgc
      541 ttttttcttt tcctcttctt cttttttctc tttatcagtg agcatcttat ctacttgttt
      601 caattgttca ttcaactgag cagatagatc tgtatttttc actttttcta ctgcttcttt
      661 tgccgtcttg tattggtcgc gtgttgctga atccactact tttccgtctt taaagactat
      721 agctgttttt tctttagctg tttgcaattc agcatattga tttttagctt ctgtttgtgc
      781 ttgttgaatc aattttccaa aatctgtgtt atccgtttcg attgcttgga tctctttatc
      841 tgctttcaac ttgatgtcat ctgctagatg atcatcgacg atggcaggtg ctatgaacca
      901 ctcattcact ttttggatat ctcggatctt agattggata tcttggtaag ttgtttctaa
      961 ctctgaatat cctttttcat tcttaagact ggataaatca ttttttagtt ttgataaatc
     1021 ttgatgaatc atatctgcac gaataaattg atggtgatca tctgtataaa aggcagcaag
     1081 tttctcatga agttcttcca tttgttgctg tctttttgct tctgctgcta cttcggcttc
     1141 tactttttga tgatggtcat aataagccca gcttcctcca ccgagtagaa gtactgctgc
     1201 taaaacgaga taaggtactt tttttgattt tttcttttgc gctttatctg gatctgtttt
     1261 ttctaagttt gattcttgat gtgttttttc agtatctggc acgattgtta ttgatttcgc
     1321 ttctgcttca aacagcttag gctggttctc ttctttttct atttttgctt caagatcagt
     1381 accctctttg cttacagatt gattttcagc atcggattca ctatttattt catcgggctc
     1441 tgttgacttt ttgtctgtgt tttcgagtat ttcttttttc tctgcttccg gcagtttatt
     1501 cgttttttcc ttttctaatt gtttttcagt aaatacttca gttttttctg tgatatccgt
     1561 ttttacgtct tttattttta ctgtttcttt acctgtggcg ttttctctat cagagtcttt
     1621 ttcagtttct tgttcctttt ctggctctac tttgttttcc tgtgcaattt tttcactgat
     1681 cattttgagc agctctttcg cgtgctcttc ttttgtatct tcacgatgtg ctttgatata
     1741 agcggatagt atcgaatttt cttcctcatt atcgacgatt tctttcagtt cagctactct
     1801 tcttttttgt tttgattcaa gcgtttcttc ttgattcttt cctgattctt ccgaagtctc
     1861 atgaacagtt gctttcttct gttcattttt ctctatatta gttacttgat cgtgagcagg
     1921 tggttcttcg tcttctggtt ctgctttttc gaataattcc attacagatt ctagaggtaa
     1981 atctttcaat tccgaccatt cgattggatc gtttaattct gtatcaggaa agactgcatc
     2041 ttcagttgat ttatcctgca tagctgcatc tgtatttgtt tcttcaattg attcttttat
     2101 ttgctgatct tctgcagtta tttgatgacc gcagtctgga cagatagtat tctgctccat
     2161 ttttttcgat ccgcaatttg gacatttttt catcacttag cgatcggctc ctttactagg
     2221 tttacgctac catttaatct atcatattct atacgtcacg ccaatagctt atttttagga
     2281 tttacttaaa aataatgaat gaatttcctt cctatagaaa aaaaagcttg agactgcgta
     2341 gtctcaagct
//
LOCUS       DADVXB010000205         2280 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.212, whole genome shotgun sequence.
ACCESSION   DADVXB010000205 DADVXB010000000
VERSION     DADVXB010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.212"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            12..>2280
                     /gene="esp"
                     /locus_tag="KB902_002671"
     CDS             12..>2280
                     /gene="esp"
                     /locus_tag="KB902_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBB6809437.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
BASE COUNT          823 a          349 c          467 g          641 t
ORIGIN      
        1 tgatttgaat aatggttagc aagaataata agagagtatt tctagaaaaa acaaagaaac
       61 gagtattgaa gtacagtatc aaaaaattaa gtgttggggt tgcatctgtt ttggttggtg
      121 ttggtcttgt cttgggaaca actgaactag ttcaagcaca agatgaaatt tctccaagca
      181 ccccacttga aacagcgata agctccgtac aagtaggtga caaagtagct tcggggaata
      241 cttttcagga gaatcctggt tatacgaaaa attataactt ttcggattta caatttagtc
      301 ctcaagaact aactggagac acactaaaag gcaatacaat tggatttgaa gtttacggaa
      361 aacataatat tgcagcatca actaaaaact gggaaatccg tcttcaatta gatgaacgat
      421 tagctaaata tgtagaaaaa attcaggtcg atccaaagaa aggaattgga tcttctagac
      481 ggacctttgt aagaattaat gattcgctgg gtagacctac aaatatttgg aaggtcaatt
      541 atattcgtgc aagtgatgga ttatttgctg gggctgaaac aactgataca caaactgctc
      601 ctaatggggt aattacgttt gaaaagagct tagatgaaat ttttaaagag ataggcatag
      661 acaatctcaa gaccgatcgt ttaatgtatc gaatctactt ggtaagtcat caagacgatg
      721 ataaaattgt accaggtatt gatagtacgg gctacttttt aacagattca gatgatttct
      781 ataatagctt agatgtatct gaaaataatc ctgaccagtt taaacatgga tcagtaagtg
      841 caaaatatga ggaacctaat actcaaacaa aagatggttc aggatccaca ggtgctaatg
      901 gagctataat cttagatcat aagttaacga aaaattataa tttctcatat tcagcttccg
      961 caaagggcac gccttggtat gctaattaca aaattgatga acgattagtt ccatatgtag
     1021 cgggtataca gatgcacatg gttcaggctg acaaagtaac atatgatgtt tcttttgaat
     1081 cagggaaaaa agtggctgat ttagcaattg aacggcgcaa agatcatgaa aattatggtg
     1141 taggttcaat tactgataat gatcttacca aacttattga ttttgctaat gcaagtccac
     1201 gtccagtcgt tattcgatat gttttacaat tgactaagcc attagatgaa atcttagaag
     1261 atatgaaagc aacagcacaa gttgaagaaa ataaaccatt tggtgaagat ttcatctttg
     1321 attcttggtt gtcggatacg aataaaaaat taatccagaa cacttatgga acaggttatt
     1381 attatttgca agatattgat ggtgatggaa accctgacga taaagaagag agcggagaca
     1441 cgaatccata tatcgggaaa cctgaattag aagaagtata tgatgttgac acaacagtta
     1501 aggggaaagt attcatccac gagttagcgg gaacaggtca caaagcccaa cttgttgata
     1561 aagaaggtac tgtattagca gaaaaaacta tcgctccaaa tgaaaaagat ggggctccaa
     1621 tttcagatac tgtagaattt gaatttacgg gtgtagattc aagtaaatta atcgcgaaag
     1681 atgaattaaa aatccaaatc gtttctccag gttttgataa accagaagaa ggttcaaccg
     1741 ttattaagga atcaccaaaa gcggttgata aacaaaccgt ggtagttgga tttaaaccag
     1801 atgctaaaga atcaattcgg aataataaaa acttacctga agatgcagag tattcatgga
     1861 aaacagagcc tgatacttct aacgttactg atagtacgaa aggtattgta actgttaaga
     1921 tcggaaatcg aactttcgac gtggatgtag agtttgctgt aaaagcttct caagctatgg
     1981 aaaatgatgc aacatacgta cctataacaa caactccaga aacgacagtt caaagtggaa
     2041 aacctacatt tgataaacca gatgttcctt tagctaaaga tgccttttca attttagatg
     2101 tctataataa ggacttcggt aatgcaagtg ttgatgcaaa tactggtatt gttacattca
     2161 ctccagctaa aggtgtagga gaatcggagc cgattactgg aacaattcct attaaaattg
     2221 tttaccaaga tggttctgta ggcacgaccg atttagcagt aactgtaagt aaagatattt
//
LOCUS       DADVXB010000206         2267 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.213, whole genome shotgun sequence.
ACCESSION   DADVXB010000206 DADVXB010000000
VERSION     DADVXB010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.213"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            101..1714
                     /locus_tag="KB902_002672"
     CDS             101..1714
                     /locus_tag="KB902_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6809438.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          710 a          403 c          445 g          709 t
ORIGIN      
        1 attttctgtc tattcaaaat aaacaataat tttccggcac aattatttgc tgttttttac
       61 cataacatag tacgatcaac gtagaaaagg agatgttttt atgaaagttg ttgtcattgg
      121 cggtgtagct ggcggtcctt catttgccac tcgtttccgt cgattgaatg aagcgcacga
      181 aatcattatc tatgaacgcg gagaaaatat ttcttatgca agttgtgctt tgccttatta
      241 tttaggaggt gtgatcactg accgtgactc gctgatcgaa cgtacaccag aaatattgaa
      301 aacaaaaaac aacatcgatg tctttactaa acacgaagta acagcaatcg atccttctac
      361 taagcgatta acagttaaag acctatccac aaatgaagaa ataaaaacag attacgataa
      421 gttgatcatc tcttctggtg ctagaccaga ttatccggat attcccggag tttttgaagc
      481 agaaaacggc tttgtcctcc gtagtgtgac ggatgcggat cgaatcaaat cgttccttga
      541 agaaaaaaat ccacaacatg tcgtcattct tggtgcaggt gttatgggtc tggaattagc
      601 tgagaatttc aagcatcgcg gcttagacgt gactttaatc gatcaattgc cacaagtcgc
      661 tttcccttat gatccagaaa ttgctaattt agtttatgac aaattgctga aagaaggatt
      721 agccgttcat ttagaaacaa gagttactga gatccgtgat aaaggtcgag aaatagtatt
      781 atcagatggc tccgtccttt ctgctgatat gctaattttt gctgttggtg tttctccgaa
      841 gaatgaagtg gtgaaagcaa ccggcataca attatcagat acaggtcaga tcattgttga
      901 tgaccagtta caaaccaatc tgccggacat ctatgcgatt ggcgatatta tcgaaacgac
      961 tagtgtagtg actggtcagc cgatccaaag tatgctttcc agtgcggcca atcgtcaagg
     1021 acatatgctg gcagatattt taaatggtac gcctatgcgc tatcgcggat atattggtgc
     1081 aggtgtcgca aaaatctttg atcatacagc aagttatgcg ggaatgacag aacatgaatt
     1141 aaaagcatca ggcataacaa attataaaac tgtttttatc actccctttg accatgccta
     1201 tttctatcca gaagctacaa gattaaatct aaagctgatt tttgatgcag atagcggtcg
     1261 tattttaggt ggacaagcat ttggagaaaa aggtgtcgat aaacggatgg gagaactttc
     1321 tgtagcaatc accggaaact tgacagtctt tgatttgcct gatttggagt tgccttactc
     1381 tccaccgtat tctactaccc gtgacccgtt gaatatagct ggttatgtcg caatcaatca
     1441 aatgacgaat atcgtagaaa cgatcaaagc aagtgatata cccgaaaacg atttgaaaga
     1501 agcgttcttt ttagatatac gtgaacctaa taaagcacct tctggcagta tctcggcaac
     1561 aaaaaatatt ccaatgaatg agttacgaga tcgaatcaat gaaatcccaa aagataaaaa
     1621 agtttacatt actttcagaa gaggattgaa tacttatact tctgcccgaa tcttggcagg
     1681 tttgggtatc aaagcgattt tgattgaaga ataaaaaaac gaccgcggtg ggtagccgcg
     1741 gtctaggagt tatttttact tgaggagtaa aaatgaaaaa gtatataggg ttgttggttg
     1801 gtatgtatat agaatagaag ataaatgtga agaaattgtg cattatttct tcacatttat
     1861 taggttatag tttaagaaag tttaaacatt gcgcaattta attattttag ctgtttcttt
     1921 tcataaaaaa acatgttgtg actctgagac aaatcatagt ccatagtgat gtctctagag
     1981 taactacgcc taatattacg aggcatcata ttaatctatc agcactagta cctaaactag
     2041 catccctttc gaatattttt tcttatataa taaagtttgc tttcactcct ctaatctcac
     2101 caaatcgact ggcttgcgtt gtgtgatact aggaactgat tggtttagaa cgacttttct
     2161 attgtaatca tatttttcgc catcctcgtt gtcttctaat ccttcaatga atgatcccta
     2221 atgtgtgtat taaataattt aatttttttg ttcctattta tttaaca
//
LOCUS       DADVXB010000207         2266 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.214, whole genome shotgun sequence.
ACCESSION   DADVXB010000207 DADVXB010000000
VERSION     DADVXB010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.214"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(187..474)
                     /locus_tag="KB902_002673"
     CDS             complement(187..474)
                     /locus_tag="KB902_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6809439.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(464..793)
                     /locus_tag="KB902_002674"
     CDS             complement(464..793)
                     /locus_tag="KB902_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6809440.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(870..1142)
                     /locus_tag="KB902_002675"
     CDS             complement(870..1142)
                     /locus_tag="KB902_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6809441.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(1142..1405)
                     /locus_tag="KB902_002676"
     CDS             complement(1142..1405)
                     /locus_tag="KB902_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6809442.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            1639..2266
                     /locus_tag="KB902_002677"
                     /pseudo
     CDS             1639..2266
                     /locus_tag="KB902_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
BASE COUNT          742 a          424 c          317 g          783 t
ORIGIN      
        1 aattaataag taaaaggtag tacataaata aggaaaagct gaaatatatt gatttatagc
       61 tttcctcaaa gtaatgacgt tatttaattt atcgagaagc agagaatact cgcgacttta
      121 gtcatgtaga tgaatcagat cttcgataaa aaagaagccg tccttcttaa gaacgacaac
      181 aaatcactag attaattttt tcaactgttc ataaaagttt tcatgcgttc cacataacaa
      241 tactggaata accttgtttt ctataatctc gtaagctact ctatatgttg tgcccgcata
      301 tttgaaccca ctagaccaaa tacctgataa atccccagtt ttttgttcac ccttatatgg
      361 atcaatcgca atttcatcat aaattaaatt caaaaatttt tctttcaatg gcttctcttt
      421 tagctttttt aaatacttaa tgacatgttt tgaaggaacg atttcataag ccaatttctg
      481 ttgccaactc ctctttagtc attactttag aattagtaag tgtatcttca gcaatatctc
      541 taaaggaaga atgcattttg ttttttctat tcttaaattc tacaagaatc tcatctttat
      601 cgtagccttc tgcaattata tcagacaaaa tatcttcgct aaaatcataa aattcttttt
      661 gtggttcaac aaattcataa agaataccat tctctaccaa ctttgcttca acttcgactc
      721 cattaggaac attaaaatct ttaggtactg tcaacatgat tgaattgcct tgttttcttg
      781 tttttgtaat catttaaatc cctcatttct aacagtatgt aattacttag taaatacatt
      841 ataccacgag ataatgtatt tacaagtaat tactgtgact cgtaatgcgt ccttgctgaa
      901 taaatttcaa ccacgtgttc atcttcatct accttataaa caacccggtg ttgtctattc
      961 aatcttctag aatacctacc ttcatgtgta ggttttaact tctcaaatga ttgggtaggg
     1021 agatagggat cttcctttaa agtctgaata accttctcaa attgaggttt caaattagac
     1081 tgtttgattt tctttaaatc agctttagcc gagtttttaa tcatcacaga atagttattc
     1141 attataagtt atcccaatca atttcatcaa cattagtaaa tccactatca tctttttctc
     1201 gcttacgaac aacacccaaa gtgcctattt gctcaagtaa tagcgtttct ttgattgctt
     1261 tccaatcatc caaaccaata agcaccgcat tattttcact gcgctcacta atgatttcaa
     1321 tttccgtatg attctcattt acatctttca acaacttata aaaatttttc cgtgctgagc
     1381 taggatttaa gactgttttt gccatatcta ctccccctct aatttatatc tccattctaa
     1441 cgtacttaat taagtacgta aattcgattg ttttgtttaa attggagtac caaaacagca
     1501 ttgtaaagtg ttatccgttt cctttatacc cgtggtgcta gttaattttt tcctagagga
     1561 aaatgtctaa acatgttggt aaatcaacaa aaaaacgcat agagtagtct caaaactccc
     1621 aagaaatgag gactacatat gcgttcatca aaatatactg aacattatac agatactttt
     1681 ataacattca aggaaattat gagaactgtt tctaacatat accacaattg tgtaccagat
     1741 aagattaaaa accgaagaaa tactgatcaa ctgaagtaac gcgatacagt gattattgct
     1801 tgtgttatat ggggcataat taatggctat actagccaaa gagccacgta tagagcggtt
     1861 tgttccgtct tatttcctaa tggtgacttt cctagtagga gtcgattcac tcgcttaagt
     1921 tcaaacttag cttacactat caagattatt cgatactttt tcatcaagaa gctcaccaaa
     1981 ggtgaactag tcggaattat agatagtttt cctagtccat tatgtaaacc agttagaaat
     2041 agacaagcaa aactattgaa tcaaatagcc aaagttggct ataactcaac aaaaaaatct
     2101 tatttttatg gtcttaaaat tcatatgatc gttactaaga ctggctttcc gattacttac
     2161 tcaatcacga atccaggtgt ccatgacgtg aaagtgttag agactttatc ggaagaagcg
     2221 aatcttccca atatcctagg ggacaaagga tatattagcc ataaaa
//
LOCUS       DADVXB010000208         2226 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.215, whole genome shotgun sequence.
ACCESSION   DADVXB010000208 DADVXB010000000
VERSION     DADVXB010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.215"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            134..307
                     /locus_tag="KB902_002678"
     CDS             134..307
                     /locus_tag="KB902_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809443.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            947..1420
                     /locus_tag="KB902_002679"
     CDS             947..1420
                     /locus_tag="KB902_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBB6809444.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1429..1656
                     /locus_tag="KB902_002680"
     CDS             1429..1656
                     /locus_tag="KB902_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809445.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          728 a          350 c          325 g          823 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaaatgcac tccacacctt catactctat
      841 cattttttat aaacgatata tttttattgt ttttcgataa aaaatagttg ttttacaata
      901 attattctgc tatattttag ctatcaaaga taaaagaggg ataaaaatga aatttaaaac
      961 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
     1021 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
     1081 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
     1141 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
     1201 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
     1261 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
     1321 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
     1381 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
     1441 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
     1501 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
     1561 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
     1621 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
     1681 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
     1741 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
     1801 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
     1861 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
     1921 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1981 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     2041 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     2101 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     2161 cattattttg ataataatga ttatttattt aaaaatacat tagataacat ttgttacgac
     2221 acgaaa
//
LOCUS       DADVXB010000209         2225 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.216, whole genome shotgun sequence.
ACCESSION   DADVXB010000209 DADVXB010000000
VERSION     DADVXB010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.216"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            401..856
                     /locus_tag="KB902_002681"
     CDS             401..856
                     /locus_tag="KB902_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809446.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(1018..2190)
                     /locus_tag="KB902_002682"
     CDS             complement(1018..2190)
                     /locus_tag="KB902_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6809447.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
BASE COUNT          718 a          442 c          394 g          671 t
ORIGIN      
        1 tacatatttt attattgcat acttaataac agaactatag caaaaaatcc cgtgtatcaa
       61 aacgggatta gattaagttt cctcaatcac tattcataac acaattatta taacaagtaa
      121 gtaaacaatt gaaaaggaca tttattgaaa acggttgttt tttacttaag gaggaaattt
      181 agtgaaaaaa ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg ggtgtggtgc
      241 tactacgtct actactcaaa gcacaagttc agctcaggct tccagcagca gtaccacgat
      301 ctccgaaagt acggcagatt catcgaaaga acaagaacaa attgaaaaga aaaaagaaga
      361 agagaaacaa aaagcggaaa aagctgcact agaaaaaaaa gtgacagaag cggaatctgc
      421 tttgtcacaa gctgaagcaa atcctacaaa agaaaactat gcaactgctt cagcagctat
      481 ccaagcgcta cctgaaaaca aacaagagtt gacaagccgt cttgctgcaa ttgattccac
      541 aatcaaagca aaagaagcag aagaagaacg gaaaaagcaa gaagaaattg cacgacaaca
      601 agcagaacaa gcgcaacaag aagcaatcgc acagcaacaa gcagaacagg cgcgacagca
      661 agcagcagct gaacaggcct ctcagcaggc acaagccgca gctcctgagc aaaataatga
      721 acaaactgtc tatgtcacac cgaccggttc aaaataccat acacataaat gtggaaatgg
      781 tacgtatacc cctgccactt taagcgaagc tcaagctcgt ggtttaaccc cttgctccaa
      841 atgttatgga aactaattca aaagttatac tataataata aaattcttct gaaacataaa
      901 aaaatagaag ctggcgttcc agatagtaaa ccaaaaatag cagtttacac gtccatttcg
      961 tcagcttctc tcttttttca tttagtctgt tccctctgct tttttggaca tcttcattca
     1021 ttctttctca atcaaatagt acacctcttt ttcttttcgc agtttatatc ttcctttttt
     1081 caatttcatt gaaaactgtt tcgaatgttt atgttttaca tggattttaa gcaggagctc
     1141 ctcatgttgc aagcgatagt tcctgccttt taaatcagaa aatctcacta gtccgtattc
     1201 atcagaagct ttcacaaatg gaactttttc tctagtaata tagtgtttgc cgttgagcgt
     1261 ttttacagaa aagaccattc cttcgattgg tcgtccgttt gtgttcttta cataaaaaga
     1321 taaaggatag tttcgcttag cgatggccaa agaatctaaa taagcgatga gtagccaaac
     1381 taagccgatt gatccaagta gtataccgat aaaccaaata aaaaatttcc attttttcca
     1441 ttgatcaatt ccttggatcg ctttttttgc ctcttttgct tgataaggaa tacgatgccc
     1501 cgtcacaagc agtcgatgtg tattgaccat ataaggagta caggtaagca aagtcacgag
     1561 atctctgcct ttttggatac ccaaagaatc tacttcatca ggtaagacca cttggatttt
     1621 ttctacttga tacgccaatg tctttccatt gatctggatg aaaaactggt ctcctttttt
     1681 caacttaggc aaatctgtaa ataattttgc ttctgggagt ccacgatgcc cagaaagaac
     1741 ggcatgggtg tttttcccgc cagtcggata agaactttct tccaataatg acgttccttt
     1801 ttgcaaaaat atttccgttg tctgatcgaa tataggtaag ctgacattga tttttgggat
     1861 ttcgatgact ccaagcatat gttccataaa aaaggcatta ctaggtaaat cttttaatgc
     1921 ttttgcatca actgcttggt tgaaactgcc tatccctggt gatacgtttt gctctgccaa
     1981 ctgttggttt ttctttgtca ttttttcctg ctgttttttt atttcctctg aattcttatt
     2041 cgatgcttgc ttttgataat ggatgatcat ttgctgggca agaaaatcat tcagtgaatc
     2101 ttctacaaaa ggataagaaa agatcccgat cccaacgact aaaatgattg ccatgaagat
     2161 gtccagtatt cttattctgc ttttattcat catgtccacc tattttctaa tatgtatatg
     2221 aagag
//
LOCUS       DADVXB010000210         2206 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.217, whole genome shotgun sequence.
ACCESSION   DADVXB010000210 DADVXB010000000
VERSION     DADVXB010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.217"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            8..526
                     /locus_tag="KB902_002683"
     CDS             8..526
                     /locus_tag="KB902_002683"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6809448.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            654..1337
                     /locus_tag="KB902_002684"
     CDS             654..1337
                     /locus_tag="KB902_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBB6809449.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1646..1719
                     /locus_tag="KB902_002685"
     tRNA            1646..1719
                     /locus_tag="KB902_002685"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1680..1682,aa:Arg,seq:tct)
     gene            1878..>2206
                     /locus_tag="KB902_002686"
     CDS             1878..>2206
                     /locus_tag="KB902_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HBB6809450.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLA"
BASE COUNT          737 a          345 c          448 g          676 t
ORIGIN      
        1 gaaaacgata cctgattaca aaaaaataac ttttataagt tctataacgt tgattatatt
       61 tttaattctt attcttctcg tcgtcttggt tccccgaatt tttggtttga ctccttatat
      121 tattgaggac aaagaaatga gtccatatta tgcacaagga aatctgatat atgtacgacc
      181 gaaaaataca aatgagattt tagtcggaga tattattaca tattatgaaa attcaggaaa
      241 aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac cacgaagatt tttatacaaa
      301 agctgataca aagacttata ttgagcctgg agtagtaaaa aagagaaata ttatcggtag
      361 tcccatcttt cagattccat atattggact agtcctttca aaaacggcat ttgcatggat
      421 tcaggggtta ttctttacga ttgctttttg cctaacagga atcacagcat ggaatacctt
      481 tgtagagttg aaaaagaagc ggagacgaac acagaaattt ttgtaagaat gttaaaaaca
      541 taaatgtatt ccagagatcc aacgactctt ctgaacatga aacacgagaa aacactcatg
      601 cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa gaggaggagt agtatgcgca
      661 atgaaatgat gcatcgtcct gtagtcaaag aagaactatt ggattttatg cgtacccagc
      721 aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga agctcatgta gcagaagtac
      781 cagttattcc ccatgaaaca gttgtatttt tgaaattttt acttggacag cttcagcctg
      841 aacgaatctt ggagatcgga gcagctatcg gtttttcatc aagtgtcatg gccacgacaa
      901 tcggagaaaa cgctcatgtt acgacaattg atcgtttcga tgtcatgatc gagaaagcta
      961 aaaaaaacta tgaacgtcta ggactgacag ataaagtgac tttgcttgaa ggtcaagcag
     1021 cagatatctt gccggagttg tctggtccgt atgactttat ttttatggat agtgcaaaat
     1081 caaaatatat tgaattttta cctgaatgct tacgtttgtt aagaaaaggt ggcgttttga
     1141 tggtagatga catcttccaa ggaggaacga tcttgctccc agatgaagag attccccgtg
     1201 gcaaacgagc tatccatcgt aaattaaatg aatttcttcg tgttgtgatg gatcatcccg
     1261 atttgacatc gacaatcttg ccattaggtg atggtgtgat cttaatgaca aaggaatcag
     1321 aaacaatcga gttgtgatac atgattatgg cagcctgtag ataatcgatt gaatcgaggg
     1381 ctcaattcga acttgatgta aaagtttcta tatttgtaag tcaattaaag gatacaggaa
     1441 atctaaataa acaggagtag catgaagtca atgtagctcc tgttttcaat tgataacctt
     1501 agaacagctg aaggagaatg tctcgtttta aaagattgat ttagtagttg ggccaaaata
     1561 attcattatt tgctaattaa ataactattt cgtattgaca gaagcaattt aattatctat
     1621 aattattgat gttccgctga ttcttgtcat agtagctcag ctggatagag catccgcctt
     1681 ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc taaaaaaccg ttagaaactg
     1741 aggtttctaa cggtttttct ttgttttttg tgccaatatt gtttgttttc aaaggcaaat
     1801 aaaataaaaa aacatcctta tcgagtacaa ttataaggag caaaaaaata aaactcatca
     1861 gaaaagagga agaagatatg acgatactat ctagaatttt agtgactcta gttgcaattg
     1921 aattttttta tatcatgtat atcgaaacgg tgagaactga ttctgacacg acaagtaggg
     1981 tttttaaaat gagtaaagaa gagttaagca gaaaatctgt tcaaacattg tttaagaacc
     2041 aaggagtgta caatggacta ttaggagtgg gactacttta tggagcttat ctttcttccg
     2101 catctaaaga aatcacaagt atgctattaa tatctatttt ttttgttgca ttatatggca
     2161 gtttgactag cgatcgttgg attttactca aacaaggtgg gctagc
//
LOCUS       DADVXB010000211         2167 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.218, whole genome shotgun sequence.
ACCESSION   DADVXB010000211 DADVXB010000000
VERSION     DADVXB010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.218"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..724
                     /locus_tag="KB902_002687"
     CDS             <1..724
                     /locus_tag="KB902_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBB6809451.1"
                     /translation="QSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPS
                     LAEKIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTF
                     TLHGSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSL
                     SNYSPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFE
                     NDGTQALIKLWWPEGKIPEKKS"
     gene            810..1040
                     /locus_tag="KB902_002688"
     CDS             810..1040
                     /locus_tag="KB902_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBB6809452.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1097..2062)
                     /locus_tag="KB902_002689"
     CDS             complement(1097..2062)
                     /locus_tag="KB902_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6809453.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
BASE COUNT          720 a          353 c          422 g          672 t
ORIGIN      
        1 acaaagtaat attctcttta caatggtagg ttaccccaaa gatgtagaag aaatctacta
       61 tggacagtcg gggatttttt ctgcagatat ctcaggacat attttagttg atttgactac
      121 aagtacacca agcctggcag aaaaaattgc aaaaacagca aaagaaaaag gcgcagatgc
      181 gttagatgca ccggtatccg gtggtgactt aggagcaaag aatggtacac tgacgatcat
      241 ggtcggtgga gaagaagccg tttatgatca agtactgcct ttattcaaag aatttggtac
      301 gacatttaca ttgcatggtt ctgctgggaa aggtcagcat acaaaaatgg ctaatcagat
      361 catgattgca ggtacgatga caggaatgac ggaaatgctt gtctatgcac aaaaaaacgg
      421 acttgattta aagaaagtga ttgagacgct ttcaggtgga agtgcagcta actggtcttt
      481 aagcaattat tctcctcgta ttttaaaaga agattacaca cctggttttt ttgtcaaaca
      541 ttttatcaaa gatttaaaga ttgcattaga agaagcagaa aaaatggatc ttgtattgcc
      601 agcaactacc caagcattga aactatatga agagttggca gataaaggtt ttgagaatga
      661 cggaacccaa gctttgatca aactttggtg gcctgaagga aaaataccag aaaaaaaatc
      721 ataaaaaacg agttttttta gagaaaatca atgcaagtag gctatgcttt tgatacaata
      781 taacagaaat aagaaaagga ggacctccga tgacacattc acaattagtc gcaatcataa
      841 aacgactgga ggctatggtc gagtcagcag ataatgaact gcaagttcgc cgttttgaaa
      901 aagaaggcgt agagaagtgt acagtaactt atgataaagc gaccgataca tttgaattaa
      961 ctgaaacaga tactcatcag caatacgaat ttgataatat cgatatcgta gcgatggaaa
     1021 tctatgactt aatccaataa attttaggat aattgacatt tgaagttgaa gatgcctaaa
     1081 agaagccgag aagcaactaa tttagttgct tttcagcttc ttttttgttt aacagttcaa
     1141 tttcaaactg ttctttttct aattttttgc ggtaactgat caagatttgt acaggatcga
     1201 tttcttcttt tgacaattga cgtttcaaag ataaatgagc ttctttcttt tcataataga
     1261 agtcaggaga aacgtcacca gaggtaatca ttgtttctgc aagttgacca taacaaacga
     1321 ggtagtgctt tttctgactc tcatctgctg ctaatggcat gctgaaggtg agcgatggtg
     1381 ttcttaaaaa ctgcttttgt tcctggatcc gtctaataaa ataagtaact aattcgatat
     1441 ctttttgaag cataccggct ttttcgaaat tcaactgata gatgaaatgt tgttgtcttt
     1501 ttttcaagta agtcagtagc tttttatttc ggccttgaaa cagcccttgg agttcctttt
     1561 ttttctgttc aaaagtcatt tcctgtaggt caggaagctg gactcgcaaa gctaacaaac
     1621 taatttcaga caaccaaggc atttgataag tttcttccat tatacgcaaa atagacggca
     1681 tttttttata gagacgaaaa ggcccgtatg ttcgagccgt aggagtatct gttaatacaa
     1741 atcccttatt ggtaatatgt acataattat aattactgaa ataattcatt tgtcggttat
     1801 aaaaaggacg gtaatgttgg atcaattgac actcgagcaa taaagcatct aattccgtgt
     1861 ctactacgac gaaatcaaaa tctgttatat gatgaatcat acgtaatact ttttttgaat
     1921 gctgtttatt ctgatgaaaa tagctgctta ctctattttt gagccgtttt gctttaccaa
     1981 catagatgac cttaccatct cggtctttca taagatagac acccggcagc atggggagag
     2041 ttttcatttt ttcttttaac ataggatctc cttttacgct ttgaataaaa agactataac
     2101 aaattttgaa ataatggaca agttttaggg aattctatag ttctgttcac agaaaatact
     2161 ttgataa
//
LOCUS       DADVXB010000212         2129 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.219, whole genome shotgun sequence.
ACCESSION   DADVXB010000212 DADVXB010000000
VERSION     DADVXB010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.219"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>2129
                     /gene="acm"
                     /locus_tag="KB902_002690"
     CDS             <1..>2129
                     /gene="acm"
                     /locus_tag="KB902_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBB6809454.1"
                     /translation="KKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVDP
                     TNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGT
                     LTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVN
                     VTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLD
                     PSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKI
                     MVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGEL
                     KIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKE
                     KEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSI
                     YFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGND
                     YVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQH
                     KEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNIS
                     IPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNK
                     SKSILPKTSSKKSSFAVIIGLLIVTIC"
BASE COUNT          834 a          345 c          413 g          537 t
ORIGIN      
        1 gaaaaagtgt agaaatatta ttttatcaat gttatttatt attactaata taacatcact
       61 gattcctgtt catgtctatg cggatgcagg cagagatatc agcagtaatg tcacttcgtt
      121 gaccgtggac ccaacgaata ttacagatgg aggaaacata aaagtaaaat tctcgtttga
      181 cgaaaaaaaa caaaatatcc aaccaggtga ttatctttgg atcaattggc caagtgaagg
      241 aaatattcgc ggtgaaggat tccaaaaaga aatcccatta atgattgaaa ataaaaatgt
      301 tggaacttta acggtcagaa aagattctgc gcaggttgtg tttaatgaaa atattaaaaa
      361 cctagactca gtagaaggtt gggggcaatt tgagatacag gccagaaacg taaccgatac
      421 cggtgaagaa aatacgggac cattcaccgt gacgagcggt gataaaacag ctactgtaaa
      481 tgtgacaaag ccagcttctg gttcttcttc tagcgttttt tattataaaa caggagacat
      541 gctacctgaa gatactaagc acattcgatg gtttttgaat attaacaata acggcactta
      601 tgttgaacaa ccagttaaaa tcagtgatga aatccaaagt ggacaaagat tagatccaag
      661 tacgtttgaa attaatcaaa tacacttagg tgaacagaag gtttatagag gagaagaggg
      721 aatccaacaa tttttacaag atttccccag cgctacattt aatttttcag taactgataa
      781 ttacattgaa ataactatac caaaaaactt tgtcaatctt aggaaaataa tggtgagtta
      841 taagacgatc atagaaaacc cagaacaaat aaattttgag aatcattcgg aagcttggtt
      901 taaagaattt aataaacctg ctgttgatgg agaaagtttc aatcatacag ttaaaaatat
      961 ttcagcttct ggtggagtca acggtacagt tagaggcgaa ttgaagattt tcaaatatat
     1021 caatgacaca gagattggta tcccaaatgt gactttcgaa ttaagacgag cagatgaaca
     1081 gcctattcaa ggacagtcta gtatcctgtt gacttcgaat gaacagggag aagctagtat
     1141 caaaggcctg caagtaggag actatgttgt aaaagaaaaa gaagcaccca attggattga
     1201 ttttgatcca ctaagttcaa atgaactcaa attctccata aacgaaaatg atacagaggg
     1261 agtcagttta cctatttata acaagaaaaa ggttacgaac atcacagcaa ctaaaatttg
     1321 gaacggtgga accactccaa gaccgagtat ttattttaaa ttattcagag caagtacaaa
     1381 caattgggaa ccagttcctg atgcagaaac aaaacgatta gacaatggaa taacttcagt
     1441 gacttgggaa gatatccaac agtatgatga tagtggaaac gaatatacgt ttaaagtgca
     1501 agaagtagat caaaacggaa atgattatgt cccttcaggt tatcaaaaaa ttgaaaacgg
     1561 gctagtcgtt acaaatgaga ataaagaagt catttcagtc tcaggacaaa aaacatggga
     1621 agacaatgag aaccaagacg gcaaacgacc gacgacgatc acagtaaatc tattagccga
     1681 cggtcaaccg atccaacaca aagaagtaag tgaaaaagat gattggcgct atcgtttcac
     1741 aaatctgcca aaatacagag acgggcaaga aatcatctat actgtaacgg aagacaacgt
     1801 gcccgaatac agtacgacga ttgacgggta taacatcaaa aacagttata caccggaaaa
     1861 aacaaatata tctataccag gtagccatat aacaccgtgg aaaaattttc cagagaagac
     1921 agagagagag aaaattagaa atctattctc tcaaaaattg caaatatttg ctcatacagg
     1981 agaatccagc gaacaaagaa gcaattatat tagtaagaga gctgtaccta aacagataac
     2041 aaataaatca aaaagcattc ttcctaaaac aagtagtaaa aaatctagtt ttgctgtaat
     2101 cattggttta ttgatagtaa ctatctgtg
//
LOCUS       DADVXB010000213         2105 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.220, whole genome shotgun sequence.
ACCESSION   DADVXB010000213 DADVXB010000000
VERSION     DADVXB010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.220"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            382..612
                     /locus_tag="KB902_002691"
     CDS             382..612
                     /locus_tag="KB902_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809455.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(805..1992)
                     /locus_tag="KB902_002692"
     CDS             complement(805..1992)
                     /locus_tag="KB902_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBB6809456.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          654 a          423 c          361 g          667 t
ORIGIN      
        1 tataaacagc ggaagcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
       61 aaaagcaatt tccgtgaatt tcttcttatt tcttggagtt aaacgcttct gttccagcct
      121 ctttttatct gtctttcact aatgatcagt tgtagataag caagttgctt tttcttacat
      181 cataccgccc atcaagacaa atgtttttca cttgtccaca ctggacaaaa atcccatcaa
      241 atcaaggaaa agcaacgttg gcaatgtttg aattttttag gctagaacgg actagtaaga
      301 gttttttgcc ccttttttgc ccctcaaata tcgctttaca acaagaacgt aagttcgtat
      361 aatcgttttg aggtgatttt tatgatggaa gaatttatta gaaaaaatat cagtgatgaa
      421 tatgcagact tttatgatca aagcagtaaa aaagataaat tccagatgga tgtttcaatc
      481 ttagctatat tagctttttc cgaaaataaa caacctgtaa ctgcaaaaaa agaaacagta
      541 ttctctgaag gcaaaataaa aactcgatat atattagagg tagaaactaa ttttaaaaac
      601 agatcggagt aatggttatg ctttttaatg agacagtcaa gtccacaatc ttgtgtaaaa
      661 gttcaacctc atcaaaagca caatgttttg cgttgtgaac ctaactgcca tgcctttctt
      721 tctgaggaga gaggtcagga gcagtagcgc agcgactctt gatgtctctc ctcagaaaga
      781 agagactcgc acaggttcat ggtgctaaat gttattcgaa ttaaattcta aatattttcg
      841 tggagaagcc agccactcag tgtctttttc catcaaaagt gttccaatta tccgagtgat
      901 ggaattgata tttggaaaaa tccgaatcac tcgttctctc cggcgaatct cttcgttcaa
      961 ccgttccaac acattggttg tacgaatcct tcggcggata ttttcaggaa aagacaaaat
     1021 ttgaatagca tcttcaaagc cgttttctaa aatgtcgcaa gcagcactta attttgaatc
     1081 acaaccatat ttttccaaga agtgctcttt tctttcacgt gtcaattcaa gttcagaggc
     1141 tttaaagata ctcttcaact cgtcttttac atcagaagaa actttctttg gcagcttatc
     1201 aaaaatattt ctcaaaaagt gggcttggca tctttgccag ctcgcaccta aaaagttctt
     1261 gcgaacagcc ttaactaacc ctttgtgtgc atcagaaatg accagtttta caccgaacaa
     1321 acctcgttga acgaacgatt gaaaaacggt atcccaatta tcttccgatt cgccgtcttg
     1381 aacatcaaaa ccaagaatcg tacgtcgtcc atcagaatca atgccgatac caatatatac
     1441 accttttgag acaatacgat gattttccct tactttcata tacagggcat cacacatgaa
     1501 aaatggatat tccgagcctt ctaggctccg gtttctccac tcaaaaacaa atggatccaa
     1561 ctgtttcatc agatttgaaa cgaatgattt agaaacagtc gcaccatccg ttagcagttc
     1621 aactgtttta gttactttgc gagtggagac accagaaatg accatttcaa tcatggcagc
     1681 gatcaaagct ttttcgcttc gctgatatct ttcaaagata gtaggactaa acttaccgtc
     1741 tctggttcgt ggaacatgaa gttctaacgt accaattcga gttgtaaacg aacgatcgta
     1801 gtaaccattt ctttgtgatt gccgttcttc tgaacgttca taggcatttg cctgaatata
     1861 ttgatttcgt tgttcttcca tcagctgatt aaacatgata gtcataagtg tttttgcggt
     1921 atcattcgca ccgctttcgt ttataattgc ttgaatttct tcgctttcaa aagtaaaatg
     1981 tacttgagtc attgatatca gtcctattcg agtatgtttt ctgcaaaaaa cattgtactc
     2041 ctaactgaga tcaatggctt ttttgatgct tcacttttac acaattatat ggacgtaatc
     2101 aatga
//
LOCUS       DADVXB010000214         2099 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.221, whole genome shotgun sequence.
ACCESSION   DADVXB010000214 DADVXB010000000
VERSION     DADVXB010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.221"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(559..924)
                     /locus_tag="KB902_002693"
     CDS             complement(559..924)
                     /locus_tag="KB902_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809457.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1000..1245)
                     /locus_tag="KB902_002694"
     CDS             complement(1000..1245)
                     /locus_tag="KB902_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809458.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1315..1569)
                     /locus_tag="KB902_002695"
     CDS             complement(1315..1569)
                     /locus_tag="KB902_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809459.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1733..2056)
                     /locus_tag="KB902_002696"
     CDS             complement(1733..2056)
                     /locus_tag="KB902_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809460.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT          782 a          361 c          370 g          586 t
ORIGIN      
        1 tttcgtctga aaacaaaaaa agaaagcgtt attattttag tctattttca gggggggaac
       61 cttatgataa aaaaactatt tttactatca atattaacgc tagcaatggc aggttgttct
      121 gactctggct tagcaactga actgatcaca aaatcaactg aagccacgac agaggagtta
      181 aaatgtggaa acgatcacag tgactacaga ggcttaaatc gacgatgcat gggaatatta
      241 ggcagaagca attgtaagca tcgatgtagt aatcgaagaa ggtgtagaag aagcaacaga
      301 aaaatcaaaa gaaagatcaa aagaagcaat ctgtgctgtg catcgtatac agacgtcgaa
      361 gatgcggtac ttttaaacca cgtcaggaga tgttcattta tgtctaggga agttggcgat
      421 gaaccaaaac tagagtacgc ttttagtttt gcacgtgagg atgaagataa ccctaaaact
      481 tacgacattt tagcttgatc taagatggtt aaagcttttt aatgaagtaa gaggagatag
      541 aaggcttttc tagttatatt aggtaagata aattcctttt tgctccaaat ttgctaaaca
      601 ttctgctaga taaacttcat cgtgttccgg ataaatcggc acgttgcgct ctacagtagg
      661 taaatcaaaa aatgcttcgc atgatttgcc acgatacata ggatttttcc actctggtgc
      721 tgggctgtaa ccacgttttt ccatttcatc catgacaagc tgatgatatt ggaataatct
      781 ataaggagaa tagtgaaaaa cataatccac agtagcatgt ttctttcccc agccatttcc
      841 tcttaatgca cagcattccc gatgttgtcc taaaagctgt tgacgaggaa gctttgaaat
      901 caatttttca tgccataatc gcatagaaat gtctccttta tatatagatt gttaacctta
      961 gacgttaaat gaaaaaacca gcaccaaggc tggaaaaaat cacttcagtt tgcttgctgt
     1021 ttctgagcga ccaattaggt aatcaacgga aatatcgtaa aagtcagcga tatagattaa
     1081 ttcaatgatg cttggaattt cttctccttc ttcgtactta cgatatttga ataaaggaat
     1141 acttaacgcg ctagaaacag ctacttgaga taaagatcgg ccagttctta agaaattcag
     1201 acgacaacgt aaagtatcca gtaaaatagc ttcttcgata ctcatttaat cacctttcat
     1261 tatagtagaa tagttataat gactatagaa agctacacat gcaatcaata gtactcaatg
     1321 ttttttattt aaacgtatca aataaagaat gacgatcaat aaagacaaaa ccagtcctga
     1381 taattcttct ataaaaacac tatcgggttc aaagtagttg taattaaaaa ctttccacat
     1441 aaagtagata gccggaagag tcaaaatagc taaataaaac cgttctttgt tccaattcat
     1501 aagataaaca atacttgcga ccagtgcgac cgcaggcacc caaaacaaaa ctctcaccaa
     1561 cgtaatcatg taacggactc ctcaacgatt catataataa aagataacat gttattgcat
     1621 acatcacaaa tgaaatgcta ggaaaataaa agaagaatag atcaatgaaa aatgaaaaag
     1681 cagaacagtt ttctgctgat aagcaggaac tgttccgctg aatgtgtctt atctatcgag
     1741 aaaaaatcaa tggattgata tctaagtaat tcaatacata taaaaagagg acgatcgcat
     1801 tcactaaaaa ggaaagaatg atgatcccat agcgaatgga aacatattta acaaatactt
     1861 ttgtttgaat acgggcatat ctttttcctt tatagctgag catcatgaca agaagcaaaa
     1921 gggtaatcac accttgaaaa atcattccaa taaacagaat tcctgaggtt tgataattta
     1981 attggagaaa ataagctgct gccgcaacta aatcgaataa aatcgcaata aatggcaaaa
     2041 taatcactcc taacattgag aataaataaa agaataacat tttttctaaa ataagcaaa
//
LOCUS       DADVXB010000215         2096 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.222, whole genome shotgun sequence.
ACCESSION   DADVXB010000215 DADVXB010000000
VERSION     DADVXB010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.222"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            76..933
                     /locus_tag="KB902_002697"
     CDS             76..933
                     /locus_tag="KB902_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6809461.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            934..1482
                     /locus_tag="KB902_002698"
     CDS             934..1482
                     /locus_tag="KB902_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809462.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            1742..>2096
                     /locus_tag="KB902_002699"
     CDS             1742..>2096
                     /locus_tag="KB902_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809463.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
BASE COUNT          807 a          267 c          446 g          576 t
ORIGIN      
        1 tttttggtag taactaaaaa taaatatgtt ataatagtat caaatgaata ttgctaaaag
       61 aaaagaggta ggaacgtggt agcgaagaaa tatgtaatcg gtaattttaa aggtggcgta
      121 ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag cagttaatga aggaaaaaga
      181 accttgataa ttgacttgga tatgcaagga aatacttctg atgtgatgaa cttaacgcat
      241 atgaacttca ctaacgaaga aggaggcgga gaaggtgaac cgattgttta cgaaaatact
      301 gtgactgacg tgttgataaa caatcttcca cctaaagagg ctgtctataa agtaatcaat
      361 aacctctata tacttccagc agacatgtcc tttgaaatgt atgatgattg gatcaaagac
      421 caatataatg attcattatc ccaattcaaa tatatgaaag aaaagctaga accattattt
      481 gatgagtttg acgtcatcta tttagatgtc ccaccttcta tttctgtata tagtaaatcc
      541 gcgatgtaca ttgcggattg ggcaatcgtc gtcttacaga cccaagtaaa atcgatgaga
      601 aatgcgatgc aatatcttga gtatatggac ttttttgtga aagaatttga tacaaattta
      661 tatgttgctg gtgttattcc tttcatgttg gaaagcggtg acgcagtaga tcaggaaatg
      721 tataaacaag cccaagagat ttatggggaa catttgatta aaaatgttgt actcaaaaat
      781 gcgcgcttaa aacgatacga cggatcaggt attacgatgg agaagacaaa gaaaggtctc
      841 ttaaaacaat gggatcgcaa aagccacgaa ttatttatca gtattttgaa agaattggaa
      901 gaacacgaga attggtatgc ggaggtggag taattggctg acatcaaagg acttgatatt
      961 tttgggaaca acaaaggact cgccaaaata aaaaaagaag cagaagcaaa gaaaaagcag
     1021 caagcaatta caccatctga aaataagcaa ttagaagtgc accaagttca agaaataaaa
     1081 acttcctcca atgttgaaag acagagtaga ggaagaacaa aaaaagttgg cgcaccaatc
     1141 agaaagtttg ataaggttta ttccaccaag catcctttaa aactgtcgac tttgttaaat
     1201 gcgacttcca gagttttagt agaaaagtat gagactaata tgacaagaga tgaattgctt
     1261 agaaaagctt tagatgagta tattaaacag aatcttacgc aagaagataa gcaagatttg
     1321 tttaatgacg tggtgaaaga actagacttg ttcagagaaa aatatccaat tgttccagaa
     1381 ttagatgatc gtggagaaat aataagaact accagtcaga taaaacaaga taccgaagac
     1441 tcactgcgca aagggtgggg aatgaataat aaagttagat aataatcaaa gaagaactaa
     1501 gtaactacct ttaaacggta gttacttagt tcttctttga tttgcgtgaa atagagggga
     1561 tttatttttc tggttacgtg attaaaaaat ccaaaaaatg agcataggaa cggttatgat
     1621 tttagggtgt gttttaatga gatattgtga tttcattaac aagtgtatga taatctgttg
     1681 ttgagttagt aaataagtaa tagagctaac tctaaaataa aactattagg aggagatgta
     1741 gatgaaaaag tttaaaaaga aaatatattt aggattggtt gttggggtga gtatgtttgg
     1801 gttcatggct catactaaac aagtaactgc agatactaac caaaaagaaa ggattatgag
     1861 ccaattagat gactctcaaa tagagtatgt acccaatgag ctaattgtca gtttaaaggc
     1921 tacacaaaga atttcaacag agaaaaataa accgcaaaat ttattgggtg taaaagttat
     1981 ggtggaaaaa gatttgactc ttaggataaa tgaaagcgat tataataagc gagatcaagt
     2041 attattagtg aaattgaacg aagaaattag tgtggaagag gcagtaagaa cattta
//
LOCUS       DADVXB010000216         2087 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.223, whole genome shotgun sequence.
ACCESSION   DADVXB010000216 DADVXB010000000
VERSION     DADVXB010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.223"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(172..354)
                     /locus_tag="KB902_002700"
     CDS             complement(172..354)
                     /locus_tag="KB902_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809464.1"
                     /translation="MKEYTTKEFEEMKRLKKDFEEVGQGQSFTIGTIQRRLRFGKERA
                     TALYNDLISDREKDFQ"
     gene            complement(811..1023)
                     /locus_tag="KB902_002701"
     CDS             complement(811..1023)
                     /locus_tag="KB902_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809465.1"
                     /translation="MDKESAREHYLSKFKRNNKPEEVFGSSVKEVGEKLTQLLKEEDL
                     TYDEAYASLQYSYNLLKYESNFIKVK"
     gene            complement(1047..1283)
                     /locus_tag="KB902_002702"
     CDS             complement(1047..1283)
                     /locus_tag="KB902_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809466.1"
                     /translation="MYWRVYKMNNASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIAVQINEQQLTN"
     gene            complement(1523..1936)
                     /locus_tag="KB902_002703"
     CDS             complement(1523..1936)
                     /locus_tag="KB902_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6809467.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
BASE COUNT          567 a          466 c          307 g          747 t
ORIGIN      
        1 tttcctttcg tttgtatgta tcgctcttta ttggtcttct atactttcgt actatctcac
       61 cgttaccgtt ttgcacagtg attacttcat acttctgttc taaatattgt ggtctataca
      121 ttgttgttaa cctcctttgc gcaaataaaa agaccactca gcggtagttt ctcattggaa
      181 gtccttctct ctatctgaga tcagatcatt ataaagagca gtagctcgtt ccttcccgaa
      241 acgtaatcta cgttgaatag ttccaatcgt aaatgattgt ccttgaccaa cttcttcaaa
      301 gtccttcttt aatcgcttca tttcttcaaa ttctttagta gtatattctt tcatgagttc
      361 attcctcctt tatgtaaaat aaaaaagacc acttaaggag tgatctcata tgtaaaaaac
      421 tacacctcag caatgagatg cagttataac cctatgtgaa cactggacta gaataccgtc
      481 tctagccaag acctacgcaa tgatacaaag cctcacacag gcaacttgcc gtgttcctag
      541 caagtccaac ttaatgtttc tctcctaacc tacacctgag agtggcgcac gtctgcgcta
      601 gtattttatg cctattaact gatttccagg cacgctggtt aattcagcca accaatcggc
      661 atccgataag attgattgtt tccgtaggtt ccttaagtca ctggcaagga atcgaacctt
      721 gcatggttgc gcttagctct tgtttctctg gtcttcaagc atacctacca gatatagcgt
      781 ctaccctttc cgccacagta acataattat ctattttact tttatgaaat tagactcata
      841 ctttaataaa ttataactat attgaaggct tgcgtatgct tcatcatatg ttaagtcttc
      901 ttcttttaat aattgagtta gtttttctcc aacctcttta acgcttgatc caaaaacttc
      961 ttctggtttg ttgttacgtt tgaatttact caaataatgt tctcgtgcac tttctttatc
     1021 cattcgtttt tcctccgatg cataaattaa ttagttaatt gttgctcatt gatctggaca
     1081 gcaatttctt cttctataag ctcaacgatc ttcctttttg tcgaatttag ttcgaactta
     1141 tgatccatta aagtaagctt tatgttctta atcttttcac cttcgaattc cttgataata
     1201 tcttcgattc tttggtttac taaaatagtt agttgatcaa ttttttcgga agcgttattc
     1261 attttatata ccctccaata cataaattaa tagacagcaa cggatgatag ataataagaa
     1321 caatttagaa ggagttggaa ttcacatcct tattcttaat atttccgctg ctgtctatcg
     1381 aagcttaatt gtgaaacaat aataaaacga tgttcctttt attattattt tgtctcagac
     1441 ctatcactaa tctttcgaca ctaccataat atcactggta aatagctaaa aaccgccatc
     1501 attccgccaa aaaaccgcca aattatttat aagcaattat tcttccgtgt ttatatgctt
     1561 ctgcaaactc tattagagct tccgacttca tccgttgtat acttctttct gaataaccca
     1621 cttcacggct aattctgtag tttgagaagc tatctggcac acagaagctg tagtaaagta
     1681 tctgacgact aatcagacta agagccatca aggctgctaa aatcgcatct ctttcagctt
     1741 ctatatccat catctgaatg attgcgtctt ctgccttatt gccgtgcttc ggtgccttcg
     1801 gcatatcggt tatgatagga gacttaatat ctatcaaaga gcgacctgcc atccgctcca
     1861 agcgccgaaa gttcttcagc acatctctcg cattacatct tgtctgtttg aaatctacct
     1921 ctcgtaacaa ttgcatcaag tcaaaccgct ccttttatgt gatataataa acttgtcgga
     1981 tttattacat cagtcggatc gatccggctt ttttatttgt cattgattag ttccatatcc
     2041 accaatctcg ctacagctaa attctctttg cttttcgcta accactt
//
LOCUS       DADVXB010000217         2086 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.224, whole genome shotgun sequence.
ACCESSION   DADVXB010000217 DADVXB010000000
VERSION     DADVXB010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.224"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..512
                     /locus_tag="KB902_002704"
     CDS             <1..512
                     /locus_tag="KB902_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809468.1"
                     /translation="NRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENFVS
                     YTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLTCGTESIVL
                     MGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPY
                     QRFERKKGQ"
     gene            893..1072
                     /locus_tag="KB902_002705"
     CDS             893..1072
                     /locus_tag="KB902_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809469.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            1203..1472
                     /locus_tag="KB902_002706"
     CDS             1203..1472
                     /locus_tag="KB902_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6809470.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            1465..1722
                     /locus_tag="KB902_002707"
     CDS             1465..1722
                     /locus_tag="KB902_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6809471.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          765 a          286 c          419 g          616 t
ORIGIN      
        1 ataatcgttt agacgtgtat aaacgtcgtc ctgaaacggt aaaaaaagga acggagcttc
       61 tacgactaga aacagaaaaa tacatcatga atgtttacct agaaaggagt gagctggtcg
      121 aaaactttgt cagctacacg atttgcagga aacactatta ctcagaatca gaatattatt
      181 caatttttga gagcatggaa ttaatggaag aagaaatgga agagctaaac agcaaagatg
      241 cgacggtaga cgattattac cttgtattta ctagattttt gacgtgtggg acggaatcta
      301 tcgtgttaat gggaatggat tatgaactca ctgtacccga agcatttttg agggaatatg
      361 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagaca
      421 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
      481 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gaggatgtgt
      541 gaaataagaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgatc
      601 caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaagag
      661 aaagaaggag atccatatga ataaaatcat tcctctattg ttcgtactgt ttgttggcga
      721 gatacttatg cgtcatggtg cagctctaca tttaaacttc gtagtattct taggaatact
      781 ggtattttgt ttgatctttt ggcgctttgt gttaaccctt gtgagtctaa tattcaagtt
      841 gattgcagcc atatttttaa tagggttatt tcgatgaaag gagagagtac taatgccaat
      901 tgcaatagga aataaacggt tacccgtgac gttggatgaa aagagacaaa aagaattgca
      961 gcaactaaag cagaagtacg gcaaaagtga atccaggatt atgtgtattg cgttagattt
     1021 attgattgcc caagaaaaag caggatttga ggtaccagca ctcaaaaagt gacgtcactt
     1081 tttatcctaa aaactaaaag tgatagcact tttaattata agaagttaga atattaatca
     1141 tttgcttaat tgtacaatat aatgtacaat tgttttatag aaataaataa ggggtgaaag
     1201 gaatggaagc agtagcttat tcaaatttcc gccaaaattt acgtagttat atgaaacaag
     1261 ttaatgagga tgctgaaaca cttattgtaa caagtaaaga tgtagaagat acagttgttg
     1321 tattatcaaa aagagattat gattctatgc aagaaacgtt gagaacactt tctaataatt
     1381 acgtcatgga aaaaattcgt cgaggagatg aacaattctc caaaggtgca tttaaaacac
     1441 atgacttaat cgaggttgaa tctgatgatt aaggcttggt ctgatgatgc ttgggatgat
     1501 tatctttatt ggcatgagca aggaaacaaa agcaatataa aaaagattaa caagttaata
     1561 aaagatatcg atcgttcccc ctttgctgga ttaggaaaac ctgagccatt aaagcatgat
     1621 ttatctggaa aatggtccag aagaattaca gatgaacata gactgatata tagagttgaa
     1681 aatgaaacga tatttattta ttctgcaaaa gatcactatt aaccaatcgg aagtaaggaa
     1741 agggtcagaa acttaaaagt ttttgatcct tattttattt accctagtca tttaaaaagc
     1801 taatatagct tagtgttgat tgttattaat gaatgtgttt gttacgcgta ttacggatat
     1861 aaggttagta aaatcatttc taaagttgag gaaaagtaaa tataaatggc ttaaatttca
     1921 acaatttgaa gttgaataga tatgttataa tactattgta gtgtgggatg ttagttacta
     1981 aaggatgacg cttatatata tgactgaata gaataagcaa taggtttaat aatctatttt
     2041 aaattttttg tactagtttt agttaattag caaaaacaac aaaaat
//
LOCUS       DADVXB010000218         2047 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.225, whole genome shotgun sequence.
ACCESSION   DADVXB010000218 DADVXB010000000
VERSION     DADVXB010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.225"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..1627)
                     /locus_tag="KB902_002708"
     CDS             complement(<1..1627)
                     /locus_tag="KB902_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809472.1"
                     /translation="MQVKKKIILSILLAIIAGLYSINYFRNVHTISTSGDIAFHFARV
                     KGLSSIFSGPINFTTFNHYGSGVNYFYPYLTFFPAVIFYWISNNLIVSYILYVWLLNV
                     CTIMLMFHYGLKFLKRIDAAFIFSCLYTFYGYRTIDIYHRSAIAEAIALTVIPIVMYY
                     AYALIYEKKPCAIPLAVSMSLLIYTHVLSTFMSVIAVGLLVLGGFVVSETRKKESIRL
                     IVELSKAVGMTILLTAYFWYPMFRQIMVQSINEPDKTTLQHQALNVSDSLIGAMNNDL
                     TTFTVGIIGIISLICPLFFFKRFNRKEKVIYLSAVVSWLLSTKFFPWSLLQNTPIQMI
                     QFPWRILGFQVLFGSLILSFVFMKSTSAKQRKVVNITTIVLLLLAVSAATKANYEHKV
                     VTQRDHLVMNQENLIRYTTLLPGGLYDYAPTEALQYKEHLQNHEVRIGKEWHTMPYQV
                     MDSKIVYTVHESKGQKITLPVFDYWGTVAKVNGQKREIVNSEGLVSIEGTQGETIIEV
                     SSIYPPTMKLAFLISLCSYLFLLISFLIRKLQHI"
BASE COUNT          702 a          363 c          321 g          661 t
ORIGIN      
        1 ttatatgttg taacttcctg ataagaaaac taattaaaag aaagaggtaa ctacataaac
       61 taattaaaaa agctaacttc atagttggag gataaatgga agaaacttca atgattgttt
      121 ctccttgtgt tccttcaatc gacactagtc cttcactatt aacaatctct cttttttgtc
      181 catttacttt tgcgactgtc ccccaataat caaatacagg aagcgttatt ttttgtcctt
      241 tagattcatg tactgtatag actattttcg aatccatcac ttgataaggc atagtatgcc
      301 attccttgcc aattcttact tcatgattct gcaaatgttc tttgtattgt aatgcttccg
      361 tgggtgcata gtcataaagt cctccgggaa ggagtgtcgt gtaacgaata agattttctt
      421 gattcattac caagtgatct ctctgagtga caactttatg ttcatagttt gcttttgttg
      481 cagcagatac agccaacagt aataaaacaa ttgtcgttat attaactact tttctttgct
      541 tagctgatgt gctcttcatg aaaacgaacg ataaaatcaa cgagccaaag agtacttgaa
      601 atcctaagat tcgccaagga aattgaatca tttgaatggg tgtattttgt aataaagacc
      661 atggaaaaaa tttggtggat aagagccaag agactaccgc actaaggtaa atcacttttt
      721 ctttgcgatt aaatctttta aaaaagaaga gtggacagat caaagaaata ataccaatga
      781 ttcctaccgt aaaggttgtc aggtcattat tcatcgcacc aatcaaacta tccgagacat
      841 ttaatgcttg gtgttgtaag gtcgttttat ctggctcatt aatcgattga accatgattt
      901 gtcggaacat cggataccaa aagtaagctg ttaaaagaat cgtcattcct actgcctttg
      961 acaactccac aatcaaccgg atgctttctt tttttcttgt ttcacttact acaaagccac
     1021 ctaagactag taagccaacg gctattacac tcataaaagt ggaaagaaca tgtgtataaa
     1081 tgagtaagct catactgact gctaatggaa ttgcacatgg ctttttctca taaatcagtg
     1141 cgtaagcata atacataact atcggtataa ccgtaagtgc aatcgcttca gcaatagcag
     1201 aacgatgata aatatcaatc gtacggtacc cataaaatgt atataaacag ctaaatataa
     1261 aagccgcatc gattcttttt aaaaatttta gtccataatg aaacatcagc atgatagtac
     1321 aaacattcaa tagccaaaca tataagatat aactaacgat taaattatta cttatccaat
     1381 aaaaaatgac tgccggaaaa aaggtcaagt agggataaaa ataattcact ccgctcccat
     1441 aatgattaaa cgtcgtaaaa ttgattggac cagaaaaaat tgaagataac cctttgactc
     1501 tagcaaaatg gaaggcaata tcccccgatg tagaaatagt atgaacattt ctaaaataat
     1561 tgattgaata aagtccagca ataattgcta ggagaatgga caatattatt tttttcttta
     1621 cttgcattac ttaattatat actcctttca tggattgctt tatctagtat aacttaaatt
     1681 ttaaataaat cgttatttat ttttactctc acttaaaaaa gcactaaaat tataagagag
     1741 ggaggtaatg gtctgaacac caagaattgt tccaacatcg aattgcttaa ctaatgagtt
     1801 caaagcttaa ttatgtggct cttatattta ccgagcgtgg attgcgatct ctttagcgaa
     1861 acaaacatct ttcataaaaa aaacagccat atccgctttc ttggatatga ctatttacta
     1921 ctactttact atctttcatt cttcttgtct cacttatgat aaggcgctgc gtatcatgag
     1981 tgaatgatat taggaaaact tcataaaata aatcttttat acatttccac ttctagatgg
     2041 ttattca
//
LOCUS       DADVXB010000219         2026 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.226, whole genome shotgun sequence.
ACCESSION   DADVXB010000219 DADVXB010000000
VERSION     DADVXB010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.226"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            35..364
                     /locus_tag="KB902_002709"
     CDS             35..364
                     /locus_tag="KB902_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6809473.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            354..641
                     /locus_tag="KB902_002710"
     CDS             354..641
                     /locus_tag="KB902_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6809474.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(920..1483)
                     /locus_tag="KB902_002711"
     CDS             complement(920..1483)
                     /locus_tag="KB902_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809475.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT          723 a          307 c          327 g          669 t
ORIGIN      
        1 taattacgaa atgtaaaata atggaggaaa taatatgatt acaaaaacaa gaaaacaagg
       61 aaattctatt atgttaacgg tccctaaaga attcgatgtg cccaatggtg ttgaagtaga
      121 agctaagctt gtagagaatg gtatccttta tgagtttgta gagcctaaaa aagaattttt
      181 tgattttagt gaagatattt tggctgatat tctttcagaa ggttatagca aacaagagat
      241 cttaaaagaa tttagaaata gaaaaaatgc gttaacttct gcatttaaat ctattgctga
      301 agatactgtt gcaaattcta aaccgatgac aaaagaggag ttggcagcag aaattggctt
      361 atgagattct accttctaaa cacgtaataa agtatctaaa aaaattaaaa gagaaaacat
      421 taaaagaaca atttttaacg ataatttatg atgagatagc agttcgtcct cattcgggag
      481 aacaaaaaac gggtgattta tcaggaattt gggctattgg attcaagtat gcaggtacga
      541 catatcgcgt tgcatatgaa attaaagata atgcagtgat acctatctta ctatgtggaa
      601 cgcatgaaaa tttttatgaa caattaaaaa agattaggta agaacccaat gtttcaactt
      661 gagaggatag acgacacttt aaaagataat ttttaacagc tgagagttgt aataccctat
      721 aattttaaac cactaaccta tatatttatg aaaaatagaa aaaattaaaa cgcattttaa
      781 gcctctttca aattaaaagc ttcatcctta tgcacaaaga gggcttaaaa tgcgttattt
      841 tatattgttt tttagtaata ataaaaaaat cactctaatt ctcccataaa tattatagat
      901 tcctaaagat taaaatagat tattccctat tgtcttttaa gtagcggtag agtgttgcct
      961 tgctaatacc agtcatttcc gtaatttctt ttacgctata aacctgactt ttatacaatt
     1021 ttactgctcg atcaacatct ttctggttca ctcgtggacg gccaccttta cgacctctcg
     1081 cacgtgcact tttcaaacct tctttggtac gttcaacaat taaatcacgt tcgaactgac
     1141 taaatgcttg gaagacagtc atcattaagc gtccgtgagg cgtgctggta tcgaagtttt
     1201 ctttcaagct caccagctta acatggtgtt cttcaaaata ggtaacaagg tcaatcaaat
     1261 cctttgtact acgacccaat cgagaaaaac tttctacaat taccgtatct cccggacgaa
     1321 ttttatcttt taaacgattt agttggggac gaaccgcttt ggttcccgtc attttctcag
     1381 ttaggatttc attacaattt tgttcattga gtaagtctaa ttgacgattt agttcttgtg
     1441 aacgtgtact cactcgggca taaccataaa tgtatccact catgcttttc ttcctttcgt
     1501 actttaattc tggcttgatt gtatcataaa agggagttat agatacatag ttaatgcaac
     1561 aagttatgat acaaaatatg acctctttta tttaataaaa gaggtcattt cattttgtct
     1621 cataatcgat tgtttttgat acgagtgtgt atacgaaata aacaaaaaaa tcttaagtaa
     1681 atttctagat acctaattta atcctaacta gtgtatccta aagttaataa cgagtttatc
     1741 acaatgaaaa ttataaaatg ctcccatatt agatataaca tgcaatattt gaattagaac
     1801 tacaaaattt attcgtttta taaagtaaat aatgttgaga tactaaggaa tagaatatta
     1861 taaggaattg agctgaatgt attggataaa aaaagaataa ctttattaga gatggactat
     1921 aaaaatgctc gtaattttct tctgaagtct gaaagctatt tgaatgctca gctaccagaa
     1981 tatattagtt ttgacgaaac tttaaaatct gctaaaaaag ttttaa
//
LOCUS       DADVXB010000220         1986 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.227, whole genome shotgun sequence.
ACCESSION   DADVXB010000220 DADVXB010000000
VERSION     DADVXB010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.227"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..644
                     /locus_tag="KB902_002712"
     CDS             <1..644
                     /locus_tag="KB902_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6809476.1"
                     /translation="SDPYIIIGAGGHAKVIIETLRLENKLIYGFFDDKQNKMQDLKYL
                     GKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIAVHPSAIVAKEIS
                     IGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPGVCLAGGVHVGVG
                     TQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKKEGINFEF"
     gene            634..1776
                     /locus_tag="KB902_002713"
     CDS             634..1776
                     /locus_tag="KB902_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBB6809477.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            1789..>1986
                     /locus_tag="KB902_002714"
     CDS             1789..>1986
                     /locus_tag="KB902_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6809478.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVF"
BASE COUNT          707 a          260 c          415 g          604 t
ORIGIN      
        1 ctagtgatcc atacattatt attggggctg gcggacacgc aaaagtcatt attgaaacct
       61 taagattaga aaataagtta atatatggat tttttgatga taagcaaaat aaaatgcaag
      121 atctgaaata tcttgggaaa ataaacgaat tgaatagctg ggcggatagc aaaaaaaaaa
      181 tctataaatt tattgtagct attggtgact gtgtagtaag aaaaaagatt ataaaaaaat
      241 tgaatatgcc aagtgagcaa tatggaatag ctgttcatcc aagtgctata gtggcaaaag
      301 aaatttcaat tggttatgga actgttattt ttgcgaatgc tgtaattaac ccagatgctg
      361 taattggaga gcatgctata ataaacacag gtagcattgt tgagcatgat tgtagaatta
      421 ataactatgt tcatttatct ccaggtgtat gcttagcggg tggagtacat gtaggtgtag
      481 gaactcaaat aggaattggt tctcaatgta tccagatgaa gaaaattgga tcttggtgta
      541 tgataggcgc agggagcact attgttaagg atattccctc acattcctta gcttatggca
      601 atccagctaa aattaagaaa gaaggaatta attttgaatt ctagaatttt attatcaagt
      661 cctcatatgg gaggaacaga agaaaaatat gttgctaagg cttttaaaga taattggata
      721 gcgccattag gtgaaaatgt ggataaattt gaagaaagta ttacaaaata tactggttct
      781 aagggcggag cttctgcgtt aagttcaggt acagctgcca tacatcttgc cttaagactg
      841 cttaatgttg gaaaaaacga tattgtcttt gctccttcat ttacttttat agctacagta
      901 aatcctattt tatatcaagg ggctgtacca gtgttcattg actcagaacc taatacatgg
      961 aatatgagcc ctgttgcact agagagcgca ttagaagaag ctgaaagaaa caaccaatta
     1021 cctaaggcaa tcatcgtagt gaatttatat ggtcaaatgg ctgattatga acgaatttta
     1081 gctattgcaa accaatttaa tgttccagtg atagaagatg cagcggaatc gttaggttct
     1141 acttataagg gaatttcgtc aggcttattt gggacaattg ggatctattc atttaacggt
     1201 aataagatca tcacaacctc aggtggagga gctctagtgt ctagtgataa aaaatatgtt
     1261 gagcattcaa gatttttagc aacacaagca agagatcaag caccgtatta tcaacatagc
     1321 gaaataggtt ataattaccg tctaagcaat atttctgccg gtatcggacg tggacaaatg
     1381 gaagtattga atgatagagt agctaaacga agagaaattt tcaatcgata taaggaagct
     1441 ttttctggaa ttgatagaat tgaaatgatg ccagaagtgg atggcatggt gccaaatcgt
     1501 tggttgtcta ctttaacgat caatgattat aattctattg atcaagtagt taacgtaata
     1561 aataaactaa atgaaaaaaa cattgaaaca agagctttgt ggaaaccact acatttgcaa
     1621 ccagtatttc aaggggtaaa aatgtattac catgataata atcttagtgt gtcagaaaag
     1681 ttatttaata gcggcttatg cttaccttct ggaagtaata tgacagatag tgaacaagaa
     1741 tttgttattg atgagtttaa aaaaatattc aagtaggtgt gatattttat gaacatagga
     1801 attattggtt taggttccat ggggaaaaga agacttagac tcattcaaga acactttaat
     1861 gatattttac tatgtggtgt tgatactaat gaggcgagac gaaaggaagt tgaaaaggaa
     1921 tttggaatac caacttataa tagtctaaca gaggcaaaaa atttgtttga aataaattca
     1981 gttttt
//
LOCUS       DADVXB010000221         1968 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.228, whole genome shotgun sequence.
ACCESSION   DADVXB010000221 DADVXB010000000
VERSION     DADVXB010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.228"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            77..1270
                     /locus_tag="KB902_002715"
     CDS             77..1270
                     /locus_tag="KB902_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6809479.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISSTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(1436..1858)
                     /locus_tag="KB902_002716"
     CDS             complement(1436..1858)
                     /locus_tag="KB902_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809480.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT          521 a          333 c          404 g          710 t
ORIGIN      
        1 aaaagtcttg tttttttatt cttttttgga tatactttta acaatttagg gaaattttag
       61 gaaaaggggt ataaaaatga caacgtatca gcgaaagtta ttattatcga catcggcggg
      121 aattgcttta gagaatatgg atattatgtt tttagctttt tcattatctt caatgattac
      181 ttcttttcat attagtagta cgcaagcggg tttcatttca acgatcacta atttggggat
      241 gctcattgga ggtatttttt ttggcatcat agctgataaa tatggacgtg tgaaagtatt
      301 ttctcaaacg gtccttctgt tttcgattgc ttctttattg atgtattttg cttcaaacat
      361 ctacttggtt tatctctttc gctttatcgc aggtgtagga gcgggaggag aatacggggc
      421 gtgtatgtcc ttgatttccg aaagtttttc aaaaaaacaa attggacgag cttcttcggt
      481 tgctggtatt ggtgcgcagg tcggtgcggc tttggctgcg attttagctg ctgtgatcat
      541 tccaacgttt ggttggaaga tgttgtatgt cgtaggtgta ctgccggtgt tgatggtctt
      601 gttcattcgt cgcggcttga ctgaaccaaa ggaattcaaa tctgtacaat ctgccgaaaa
      661 gaaaaccaaa cttagcagac tgtttgaatc aaaacatctt gcttggcaaa catgtggcct
      721 tagtatcatg gtaactgtcc aaattgccgg ctattttggg ttaatgaatt ggctgccttc
      781 aattatgcaa aatcgattag ggctttcggt ttctgggtct tcattgtgga tggtcagtac
      841 tattttaggc atgtctttgg ggatgatgac ttttggcata atcatggata aattggggcc
      901 taaactagcc ttttctttgt ttttaatttg ttcatcctta tctgtctatc tacttgtgtt
      961 agcccatagc cagtggagtt tggtagcagc cgctgtgata gtcggctact ttatcaatgg
     1021 catgtatggt ggatatggcg cagtgattag tagtttgtat ccaacagaaa tccgcgcgac
     1081 ggcgaataat ttcattatga accttggacg agctgttggt ggtttttctt ctatcgtcat
     1141 cggtttcttg atggatcatt atagtttaac tgccgtaatc ttgtttttga gcggtattta
     1201 cctagtcagt ctgctggtct tgacaactct tactggtgtt acagcattaa gggaaagctt
     1261 gcagcattga tagttgagtc tgtaaatgac aagaaagagg tgtggcaaaa gcttgcatct
     1321 gcggtaataa gaccagccaa atcaaaaaca tgagacactg tttccgtttg gctggtcgta
     1381 ttacttgatg cagggcagct ttttcaactg ctaatttcct tctatctggc ggctactatt
     1441 ctttgacgtc cgtcatttca aagtacttta ctaataactt agcataacga aaaactgtgg
     1501 atacactcgt atattgagcg tctgcataat cttccaaatt tttctcagga tgttgataca
     1561 tgaattcaat caaatgataa ttatatgatt ttctgtagaa atgaagataa ataatgtaga
     1621 ttgggaagtt ctcctgcttt tccatagaaa agcgccgatt attctcattc ttcaaaatga
     1681 ccttatcagg atatttttgg aacaattctt ctaaatctgt tagataattc aagatagact
     1741 tacttgatac cttcaattcg ttttgtagtt cttctattga acaccaacgt tctgtttcaa
     1801 gcagtaaatg aatcatttta attttctttt gagaaacttt tgttaaaaaa gtctgcatat
     1861 tttctcctcc tgtatctact ttactatact acatacaaga aaaaaaacgg atacaaatat
     1921 catattgtca caccgtcaat agtgcataaa cctgttatta tttctctt
//
LOCUS       DADVXB010000222         1965 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.229, whole genome shotgun sequence.
ACCESSION   DADVXB010000222 DADVXB010000000
VERSION     DADVXB010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.229"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="KB902_002717"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="KB902_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6809481.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="KB902_002718"
     CDS             852..1040
                     /locus_tag="KB902_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6809482.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="KB902_002719"
     CDS             1053..1610
                     /locus_tag="KB902_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6809483.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="KB902_002720"
     CDS             1642..1884
                     /locus_tag="KB902_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6809484.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          717 a          305 c          404 g          539 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaac
     1921 aaatttgaga accgtagcga cactcgctgc ggttcttttt tatat
//
LOCUS       DADVXB010000223         1956 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.230, whole genome shotgun sequence.
ACCESSION   DADVXB010000223 DADVXB010000000
VERSION     DADVXB010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.230"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..167
                     /locus_tag="KB902_002721"
     CDS             <1..167
                     /locus_tag="KB902_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6809485.1"
                     /translation="KISFEENIVKEMPESANDMYEKELKYFFENVVTGKENWNDLYHA
                     NEVLKIAEEK"
     gene            168..920
                     /locus_tag="KB902_002722"
     CDS             168..920
                     /locus_tag="KB902_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBB6809486.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            925..1872
                     /locus_tag="KB902_002723"
     CDS             925..1872
                     /locus_tag="KB902_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6809487.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          684 a          263 c          389 g          620 t
ORIGIN      
        1 ataaaataag ttttgaagaa aacattgtta aagaaatgcc tgaatctgct aatgatatgt
       61 atgagaagga gttgaaatat ttctttgaaa acgtagtaac aggcaaagaa aactggaatg
      121 atttatatca tgcaaacgaa gtattgaaaa tagctgagga gaaataaatg gaaattttat
      181 ttactatttg tggtagagct gggtctaagg ggtttaaaaa taaaaatttg aaatatttgg
      241 caggaaagcc cctagtccat ttcgctttag caatgataga tatctatcaa caaaaacatc
      301 ctgaacataa ttgcacgact tgtttgaata cggacagtaa tgagttagta gaattgacga
      361 ctaagttaaa tccgtctgtg aaaattgtag aacgtaaacc tgaattagct acagatactg
      421 tagggaaaat tgaagtgata cgtgattcat tcttacaact agaaagagaa gataatatat
      481 ttgatttaat tatagattta gatttgactt cacctttacg tgaagtttct aatcttgaag
      541 aattaataga tgaacatcta aaaaatttag ataaagacgt ctacttttca gttgtttctg
      601 caagacgtaa tccctatttt aatatggtaa aaagaattga aaatgaagtt actatagtta
      661 ataaatcaag atacacatct aggcaacaga cacctgaagt ttttgaaatg aatgcctcaa
      721 tgtattcttt taaacctgaa tttctaaaaa aaagtaatta tatttttgat gggcaatgtg
      781 ggataataaa aatgagagat tatctaattt tagatattga tagtgaagaa gattttaaat
      841 ggttagaatt tttgtttcct aaatttttag aagattcttc ggagcttcaa gatatctata
      901 attatttata tcggaggtaa aaggatgagc tgttatctta tcaccggtgg ggctggcttc
      961 attggttcta ccttagccaa tcatttagga gaagaacatg tggtaatcgt cgtcgatgac
     1021 ttatcaatgg gaaaagtaga aaatcttgat atgacgaaaa atatcacttt tattgaggga
     1081 gatgtcgctg agaaatcctt gatggaagag atcatgaaag ctaataaatt tgattatatc
     1141 tttcatttag cagcagttgc tagtgtggca gattcagttg cccgaccagt agaaacacat
     1201 cgtgtgaatt ttgaaagtgt attaatgatt ttagaattga tccgcaagta tcaacctgat
     1261 ttaaaacgga tcgtgtttag ttcttcagcg gctgtttatg gggatgaacc gactttacca
     1321 aaaaaagaag agtccgtgat tcgcccattg acgccttatg cggttgataa attcgctgca
     1381 gaacaatatg tgctagatta ttgtcattta tatgatgtac ccggtagcgc agttcgtttt
     1441 ttcaatgtct atggtccaaa tcaaaatccg aattctccat acagtggtgt gatttctatt
     1501 ctcgtagatc gctataagaa acaaatcgta ggagaagcaa cttcatttac attatttggt
     1561 gatggaagcc agtctagaga ctttgtttat atagatgatg taatccaagc attactttta
     1621 gttgcgaatg aggaagctgc actggggaaa caattcaatg ttggaacggg taaagcaacc
     1681 acacttttgg aattgattca tgcaatcaat gaaattctcg gtgtagaatt gacacttgaa
     1741 tacaaagaag agcgttcggg tgatatccat gactctctag cagatattac taagatccag
     1801 tcaattggct atcaaccgaa atatggtatt ttaagtggaa tgactaatta tttgaaaact
     1861 gaaatcaatt aaaacatact aagataagat tagagggtaa attcaggctc tttgtcaata
     1921 aggactgatg agttttgtaa aatcaaatct gggata
//
LOCUS       DADVXB010000224         1932 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.231, whole genome shotgun sequence.
ACCESSION   DADVXB010000224 DADVXB010000000
VERSION     DADVXB010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.231"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            202..1167
                     /locus_tag="KB902_002724"
     CDS             202..1167
                     /locus_tag="KB902_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6809488.1"
                     /translation="MSKRGTIINEWENLTALSNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKINQFLASSMKNFIHDLFLEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPKEIETWWRLELQ
                     LRRGKATDWHEMVHESLDSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLKQELDTWLLGLDVTEK"
     gene            1367..1570
                     /locus_tag="KB902_002725"
     CDS             1367..1570
                     /locus_tag="KB902_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809489.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFNLGFSISFKKGTKN
                     TSISHNNRELTDSQKINSLSGRK"
BASE COUNT          637 a          281 c          430 g          584 t
ORIGIN      
        1 aaaaaaatag tcgagcagtg ttgacgcact ctcgaccttt acggaaacta atcacactag
       61 ctccgtaact tcttaatcat tatacgaata tttttagatt tcttcaagac tagagatttt
      121 ttggtaatga atttttaaga gttacgtgaa cttttgaaaa ttctttccag aagtctcttt
      181 ttctttgagg aggaataaaa tttgagtaaa cgtggcacga tcataaatga gtgggaaaat
      241 ttaacagccc tatctaacag gcggttaaat gttcaaaatt tgaacacccc cctaaaatta
      301 cagtggtcaa ttgaccgaat taccattgtt ggaaaactga aagaaaatat ttattatcat
      361 actcaaaatg atgtattgat tttagacttt gaacagttaa tgcgactgaa tgaaaataat
      421 ggttatgtta aatctgttgg tctaaatggt tggcaaattg tggataagca tgatgagaat
      481 attgcttaca ttgaaatttt gaaatatcaa gaaggtcaag ggcgaattga ctttaatccg
      541 aataaaatta atcagttttt agctagctct atgaagaatt ttatccatga tttatttttg
      601 gagccgcatt tttcacgtgc ggatattgct tgcgatatta tcgatgtgcc tgatgagttt
      661 attacccaat atcgggtggt tgatcctgta tcgtttaaac caatttatgg tcggtctggc
      721 aagttagaaa ctgcttattg gggcagtcgt gctagtgaac gtcaaattcg gatgtataac
      781 aaaaaattag aacaagaaag aaaacggaaa attgttccga aagaaatcga aacttggtgg
      841 cgtttagaat tgcagttgcg acgtgggaaa gccactgatt ggcatgaaat ggttcacgaa
      901 agtttggata gttttgcgag cctgcatttt ttgccgattg atacaacacc tacagataga
      961 ataatgctcg ctggtttaat gtctgatcaa aatttctggt ctcttttgtc gaggaattca
     1021 aaatataaat atcgggaatt gctgaaagaa gaaagtcaaa atgatgaatt gacgaatcat
     1081 ttgcgagaaa cgtttgcaga atcggcagac aatttgaaac aagaattaga cacgtggctt
     1141 ttgggtttgg acgtgacaga gaagtgatac cgaataagaa aagtcagatg agtgagagta
     1201 aatttacgtc aatgtttaat gacgtgagtt tacgataagc gattattttg cgtgaagcaa
     1261 aataaagcgt aaaaggagtt gagagcgtga cacgctttcg gctccttttt tcgttgtcac
     1321 ttgtgacagc gaataccctc ggagagcatt tggaattgtg acagccatgt cacaattagg
     1381 aaaatgttac tctttgtcaa agagtaacag aaaggtttac actcttttta ttagcgacag
     1441 cgcgaaggag gggtttaact tggggtttag tatttcgttc aaaaagggaa caaaaaatac
     1501 aagcatttct cataataatc gtgagttaac tgatagccaa aaaatcaata gtttgtctgg
     1561 tagaaaataa ttagcagatt tacaagtggg aaataaaaag ctgaaagaag aaaattgcat
     1621 ttcaaactac attttctaca ataactctaa aatggcatat tttgcgttct gagcggtttt
     1681 agcgtttatt tcgtttagtt atcggcacaa tcggtgaaac acgttagagg agcgaaaatg
     1741 gagcctgtaa ggcgactggt agcggaacgg tcgtgttaga ttgtgtagcc gatagctgaa
     1801 cgaaataaat gctggcagcg ccattctatt tcggcaggag gaggctcaag gggttcgggg
     1861 aatgaaattc cctgaggtct ttttattttt tctagaggag tgctataatc aaagaaaatg
     1921 agaaaaaaga gt
//
LOCUS       DADVXB010000225         1912 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.232, whole genome shotgun sequence.
ACCESSION   DADVXB010000225 DADVXB010000000
VERSION     DADVXB010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.232"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..435
                     /locus_tag="KB902_002726"
     CDS             <1..435
                     /locus_tag="KB902_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6809490.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="KB902_002727"
     tRNA            complement(759..842)
                     /locus_tag="KB902_002727"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="KB902_002728"
     CDS             1370..1870
                     /locus_tag="KB902_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6809491.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
BASE COUNT          617 a          361 c          328 g          606 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt ta
//
LOCUS       DADVXB010000226         1896 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.233, whole genome shotgun sequence.
ACCESSION   DADVXB010000226 DADVXB010000000
VERSION     DADVXB010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.233"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(640..930)
                     /locus_tag="KB902_002729"
     CDS             complement(640..930)
                     /locus_tag="KB902_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809492.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1138..1830)
                     /locus_tag="KB902_002730"
     CDS             complement(1138..1830)
                     /locus_tag="KB902_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6809493.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          514 a          365 c          293 g          724 t
ORIGIN      
        1 tatcttttaa atacttaatt gttaaatacc ttatttgatg caaaagaaat ctacgatagt
       61 caacaaaaaa attttcatta tatccagaaa aatttttctt agttaaggac ctatggattg
      121 cagtaatgca gaattcgtcg aataaactgc caaagacata caatcatatt gcttttaaaa
      181 ttgacgaaca agatatagat tcgtttgtct caaaaatcca aatgttaggt ttaactgtcg
      241 aaccaggacg ttctcgtgtg aaaggcgagg cttcttcaat ttacttttac gactatgata
      301 atcacctctt cgagttacat accggtactc tccaggaacg tttaaaatcc tacaattcca
      361 ctacctgaga ctagtaatga ctagtctctt tttatggcct ctgatccccc cattgagcga
      421 atactaatag ggcttcgaat tgatctgttc aatctttaag caatatccct caaatgagtt
      481 tggaaagttt agtgattcat cacaaatact taaatacatg tagttatata tagattgagg
      541 ttcttgtgag cgtatgctcg tgtgggttca aatcccatcg tctgcatcca tctttccaaa
      601 acaagcggct aggacatttt tgtctcagcc gcttgttttc tagtttattc tttcatcttg
      661 tcggaccttt tttcttgggt atagactttt ctcatattct accacaattt tgggtttccc
      721 taacacatga taggatctca caacaaattg ctttctatta ttataataac ctgtaacgac
      781 taacttcatc ccttcgtcta cttcagctag gaagttcaaa ctatgggaag caatcaaaca
      841 attgacccca tttaaactga aacggatcaa cggtctggca ctaacttgca aagtacggat
      901 cttatctact gttccatatt ttttctccat aaccttcacc tcaataccat tatacgaaca
      961 tacattccct ttgtaaagaa gaaactctgt tttatctttt tgactttttg tctattacct
     1021 ttcttaaaat catattggca cttcctgcga agatgaagga catgtactaa aaaaaagagg
     1081 cagcagtata gattactgtt gcttctttac taatttaggt ttacttgtta agaaagatta
     1141 tttacgcaaa tgttcttcaa caatttgctg agatttatca gctgtatctt ccacttcatc
     1201 ttttgctttt tctaactttt gaatatattg tttcaagctt gagttttcag cagttgcttc
     1261 gtctaatttc ttttgtgtat ctgttaactg agtttctaca tttgtttttt cttgtgtcag
     1321 tgttgcgatt tgttgattca aaccatttac agtattttgt aattctgaaa gttttgcttg
     1381 tgcttcttgt agtcttgctg tccaatctgc attcagatga ttgatttcat catttttttg
     1441 gttgatctca tctagtttga cattgatttc attttgtttg ctttgtagtt gtgcatcctt
     1501 gctgactaat tgactttcta agttttgttt ttctgctgcc gattgatttt tttggttttc
     1561 taattcattt acttttgttt ggtattcttg gacatctgcc tttgaatctt gcaatgtctg
     1621 ttctttttgt gctagtcgag cggtaagatc tgtaatcgct tgctctttat ctgtcaatgt
     1681 atgatcaagc tgtgtcagat tctcattgat tgtatcaata tctgtctctc caccccacaa
     1741 aataatttca tttgcgtacc gcgtgcctgt gtagccaatt agacatagaa atgcaacgac
     1801 aatcccacca gtaataaatt tctttttcat ttgcatagct ccttaatcca atacttttac
     1861 atgctaaaag taagtgatct caaacacaat gtcaag
//
LOCUS       DADVXB010000227         1857 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.234, whole genome shotgun sequence.
ACCESSION   DADVXB010000227 DADVXB010000000
VERSION     DADVXB010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.234"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(31..732)
                     /locus_tag="KB902_002731"
     CDS             complement(31..732)
                     /locus_tag="KB902_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6809494.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(748..1188)
                     /locus_tag="KB902_002732"
     CDS             complement(748..1188)
                     /locus_tag="KB902_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6809495.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1188..1763)
                     /locus_tag="KB902_002733"
     CDS             complement(1188..1763)
                     /locus_tag="KB902_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBB6809496.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT          519 a          401 c          288 g          649 t
ORIGIN      
        1 ttttctttcc cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg
       61 gttatccgta aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat
      121 ctgacggatc accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc
      181 cacttgtatt ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa
      241 cgtttcataa taggtatata acgtctcatc gctttctagc tgttcatagt cacgcccacg
      301 ttttttgata cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg
      361 ccgttttttt ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta
      421 ctgctgtact tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct
      481 atcttcatag atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc
      541 taaaaatcgc ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga
      601 ataaaagagc ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat
      661 ctcttttgca agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa
      721 aatcactgac atacaaccct tcctcttcta taagtactcg cctacgtaag tttcaacagg
      781 caatgtttca aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact
      841 ttgtgtaatc atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt
      901 caacatagtt gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa
      961 gtcaaggata gccacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac
     1021 ttcctgcgcc catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga
     1081 gtagaaactt gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc
     1141 gatttgctcc tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc
     1201 ttcaataata actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga
     1261 ttgttggaaa agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa
     1321 gtttctaata attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc
     1381 ttgtcgggcg tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta
     1441 cctagacctc cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt
     1501 tcatcgatcg tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca
     1561 aaaagcccat tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta
     1621 atcactccca taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc
     1681 atgtattttc ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa
     1741 ccgcaaaaaa cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt
     1801 ctacacgtgt ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatata
//
LOCUS       DADVXB010000228         1839 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.235, whole genome shotgun sequence.
ACCESSION   DADVXB010000228 DADVXB010000000
VERSION     DADVXB010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.235"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..722
                     /locus_tag="KB902_002734"
     CDS             <1..722
                     /locus_tag="KB902_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6809497.1"
                     /translation="FLSTPFDEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLP
                     VLLSTGMADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVG
                     YSDHSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEI
                     FLGDGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQY
                     IGKKVKRPISADSVLLEEDVE"
     gene            719..>1839
                     /gene="neuC"
                     /locus_tag="KB902_002735"
     CDS             719..>1839
                     /gene="neuC"
                     /locus_tag="KB902_002735"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBB6809498.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDI"
BASE COUNT          671 a          240 c          359 g          569 t
ORIGIN      
        1 attttttgtc tactcctttt gatgaagaaa gtgcagactt tctaaaacaa attggtgtac
       61 aaggatttaa aattggctca ggagatttaa caaatttacc ttttcttaga aaaatagata
      121 tgtatgggtt gccagtttta ttatctacag gtatggctga tattcatgag gtcagtgagg
      181 ctgtagattg tttcatagat agtccagtta ctattttaca ttgtacttca aattatccgg
      241 ctagttctga agatattaat ttattggcga ttaacacatt aaaagaaatg ttcgggatac
      301 ccgttgggta ctccgatcat tcattgggat atgatgttgg tatttgtgct gttgcgatgg
      361 gtgctaaggt aattgagaaa cattttacct tggataagga actacctggt ccagatcata
      421 aagcttcttt agatcctcag gaatttgcag attttgtaaa gcatattaga aacactgaaa
      481 tatttttagg tgatggtgtt aagcgagcaa tgccttctga acttagtaca aaagaagtat
      541 caagaaaaag cctagtggtc actgagaatt taaatgtggg agatattctt acagagaaat
      601 ctcttacaat aaaacgtcct ggaaatggaa tagctcctaa gtttttatat caatatattg
      661 gcaaaaaagt taaaagacca ataagtgcag atagtgttct gcttgaggaa gatgttgaat
      721 gaaaaaaata cttatagtaa gtggaacacg agctgattat ggaatatata aacctgttgc
      781 tgagaattta ctacaagata attgggatgt atcatttgtt gtttctggaa tgcatttatc
      841 ccataaatat ggatttacta aagaattgat cttagctgac ggatttagaa ttagtggaga
      901 agttcaaagt ttgtttttag agaacaataa gggaaacatg gctcggtctg tggcattaga
      961 gataaatggt ttcacaaata tatttgaaca aactagccct gattttgtat tattactagg
     1021 ggatagagga gaaatgttgg cagctgcgat agcttgtttg tatcttggaa tcaaaacagc
     1081 acatattcac ggaggcgaag tgtctggtac tgtagatgaa tcaataagac atgccataac
     1141 gaaaatagca tctgttcatt ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat
     1201 gggggaagat tcttggagag tttttcccgt cggagctcct agaatagata ctattttaaa
     1261 taatagatta cctagtttta gagatataaa agaaaaatat catctaaaat ttgaaaagaa
     1321 aaaatacgtt ttgcaagtat ttcatccagt tgtaaccgaa ctagaaaata tagaaaaaca
     1381 aattttagct ttgatcaatt caatggaaca acaatctcaa ccaattattt gcattttacc
     1441 taatagtgat gctggtagcg aaattatcag aaaaatgtac cagaaatatt taaaaacgga
     1501 tattatttat attacgaatt tagagccgga ggaatacctg actatattaa aagagtgcaa
     1561 atttatgatc ggaaattctt cttctgggat aattgaagct gcatcattca aaataccagt
     1621 aataaattta ggaaccagac aaaatggacg agaacaatct aaaaatatta taaatgcaaa
     1681 tctaaatgaa aatgaaattg aaactgcttt gaataaaata caagatcctc agtttataaa
     1741 aagcttgaaa aatgttaaga acatctacgg tgacggcaac agttctagaa gaataacaaa
     1801 aacattgaat caaatattga atgatgggga agatattaa
//
LOCUS       DADVXB010000229         1801 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.236, whole genome shotgun sequence.
ACCESSION   DADVXB010000229 DADVXB010000000
VERSION     DADVXB010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.236"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            290..697
                     /locus_tag="KB902_002736"
     CDS             290..697
                     /locus_tag="KB902_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809499.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            711..1112
                     /locus_tag="KB902_002737"
     CDS             711..1112
                     /locus_tag="KB902_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809500.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1114..1485
                     /locus_tag="KB902_002738"
     CDS             1114..1485
                     /locus_tag="KB902_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809501.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1521..>1801)
                     /locus_tag="KB902_002739"
     CDS             complement(1521..>1801)
                     /locus_tag="KB902_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809502.1"
                     /translation="LWFKFDPTNRFVKDFYKVWDSEVFFLAIEDSLLINLYYSNKNYF
                     KIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          670 a          235 c          306 g          590 t
ORIGIN      
        1 ttttgagggg aagtacatat agttgttgat atagttgcta atattgttag ctaatttgtt
       61 agtaaaactg tatacgaatt tagatagtaa aaaaacagtt tgttccttat atagaggcac
      121 ttttactact gattaaatgt cagatatgct tacaaatata cttataaata tgcttacaaa
      181 attagctaat atttccgttg acaaagcttt gttactattg ttaaactaaa ttgactagca
      241 aaagtgaaac ataaatttat taaataaatg taaaaattag gagaaatcaa tgtcttatag
      301 agtacaatta ataatttcag aagatgtaga aagtcagcaa tttggcacta atgttattaa
      361 taaagtaatt aatccagctc tttctattaa tgcgccttta attcctactg ctttatcatt
      421 ttctgtaaca gctgtggtgt ctgagataga ggatacagaa aagataaaaa tagtagaaat
      481 tgaagtttta aacaagaatg aaaaacaaat tttttctacg ggtgaagtat cggtaagctt
      541 gcctcctcaa gttaacgata taaactttaa tataaacgcc agaaatgtct tggttgaaga
      601 agcaggagag cattatgctg ttgttaaatt taatggaact gagattggaa ggcaaatctt
      661 tgatatcaag gtcaacaaac cagtggaaaa aaattaagga gacgatacgg atgcttgata
      721 tagtaccatc aaatacacat cggagtggta gcttaataaa ttttgctgcg atttttgctt
      781 gcgcatcggt aattctagca tctccagttg ttgtggatgc aagttctact ccgaaaacta
      841 aaaatgataa tcaacttgta attactacaa aaaatgagat taacacaatt tcaagtaatg
      901 atggcaaaat ttttgatgtg ataaatacgg ttttaaaaag aaaagctgaa atcaatataa
      961 aatatgatga agatttaaac ttgtatttct ttgttatcaa aacaacatct gaattgtttt
     1021 cctcagatta cgatgttttg gatactctcg ataatgtatt atctgactat aaatatatgg
     1081 ggaaatctgt agtagcaact ttgggggaat aaaatgtttg actttaatga atatttatct
     1141 atttccaaac aaattgaatc agatgataaa tataattcta aagaatctta tagaagaact
     1201 gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt gaaagaaaat
     1261 tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt ttggaatttg
     1321 ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta tagaatgtta
     1381 gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac agatatggcg
     1441 ctgatgaatc gagaagcaga aaaaataata aacaaactca cctaatgaat ttcaagcgag
     1501 tttgtttgtt atttttttat ttaatctttg tatctttctg gatcaacgaa agtatacttt
     1561 atatagtcat aacgccgatg atcgctacgt gcgtccggca cgtcagtcac gatatcaaac
     1621 aaaaaatata cgtctttctt cattctagtt tttgcagcag ggattttaaa gtagttctta
     1681 ttagaatagt agagattgat taataagcta tcttcgattg ctaaaaagaa aacttctgaa
     1741 tcccacacct tataaaaatc tttgacaaat ctattcgtag gatcgaattt aaaccataat
     1801 t
//
LOCUS       DADVXB010000230         1745 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.237, whole genome shotgun sequence.
ACCESSION   DADVXB010000230 DADVXB010000000
VERSION     DADVXB010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.237"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..330
                     /locus_tag="KB902_002740"
     CDS             <1..330
                     /locus_tag="KB902_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6809503.1"
                     /translation="ESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILA
                     DEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVN
                     KMNLEVE"
     gene            330..1706
                     /locus_tag="KB902_002741"
     CDS             330..1706
                     /locus_tag="KB902_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6809504.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
BASE COUNT          698 a          197 c          307 g          543 t
ORIGIN      
        1 gaaagtatct tgtttgaact aggtttagat aaaaaacaaa taaaaagaaa tgttatgaaa
       61 ttatctggtg gacagcaaca aagagtagct attgctagag cattggtatc agatgctcca
      121 ataatactag ctgatgagcc tactggtaat ctagacagtg ttactgctgg agaaataatt
      181 aatatattaa agacattagc taaagataga aataaatgtg taatagttgt aacacatagt
      241 aaggaagtag cagattctgc ggatatcatt ttagaactaa gtggtaaaaa gttgaaaaaa
      301 gtaaataaaa tgaatttgga ggttgaataa tgataaaaaa tgcatttgct tatgtaacta
      361 gaaaaagttt aaaatcatta attatcatat tagttatttt atctatgtca actttaagtc
      421 tcattagttt atctattaaa gatgctacgg acagagcttc aaaagaaaca tttgctaata
      481 taacaaatag tttttctatg gagataaata gacaagtaaa tccaggaaca cctagaggtg
      541 ggggaaatgt aaaaggtgaa gatattaaaa agatatctca aacagatagt atagactcct
      601 atgtaaaaag aataaacagt gttgcagatt tagttgatta tgatattatt gaaactcaag
      661 agactcttgc gaatcaatca cctgaaagag caaagaattt taaaagaaca gttatgttaa
      721 ctggggttaa cgactcaaca aaagaaacaa aatttgtatc agaagcatat aaattagtag
      781 aaggaaagca tttagaaaat gaagataaaa ataaaatctt aatgcataaa gatttagctg
      841 aaaaaaataa ccttaaagtt ggagataaga taaaaataaa atctaattta tttgatgctg
      901 ataatgagaa aggtgcagat gaaacagtag aagtagaaat taaaggtcta ttcgatgggc
      961 ataatagcgg tgtagtaagt gcagcacaag aactatacga aaatacatta atcactgata
     1021 ttcatacagc tgctaaagtt tatggtaata ccgaagatac agctgtatac caagatgcaa
     1081 cattctttgt aaaaggtgat aagaatcttg atagtgtaat aaaagatctt gggaaattag
     1141 atataaattg gagagaatat aatttgatta aaagttcatc aaattaccct gcattacaac
     1201 aatctatatc aggtatttac tcaatttcaa ataaattatt ttttggctca ttaatatttg
     1261 caggagttgt agtttcatta ttattattct tatggatgaa tgctagaaag aaagaaatag
     1321 cagtattact atcattaggt atatcaaaat tagaaatttt tggtcaattc ctaattgaga
     1381 tggtatttat atcaatcccc gcattcgttg gttcctattt cttagctcaa tatacagctg
     1441 acaagcttgg gaataatata ttgaataagg ttactggtga tatagctaaa caaatagcta
     1501 aacaatctgc atctagccaa ttaggtggtg gggcagaagc tgaaggattt aacaagacat
     1561 tatcaagttt agatatcaat gtattaccta aattcatgat ttatgtagtt atatttatga
     1621 gtttagtact tcttgtatca ttgattattt cttcattcaa tatattaaga aggaatccaa
     1681 aagaattatt aattgacaat aattaaaatt ttcggtgctt tttagcacca aaaatgagag
     1741 tgtaa
//
LOCUS       DADVXB010000231         1718 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.238, whole genome shotgun sequence.
ACCESSION   DADVXB010000231 DADVXB010000000
VERSION     DADVXB010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.238"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(128..1276)
                     /locus_tag="KB902_002742"
     CDS             complement(128..1276)
                     /locus_tag="KB902_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809505.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1293..1697)
                     /gene="tnpA"
                     /locus_tag="KB902_002743"
     CDS             complement(1293..1697)
                     /gene="tnpA"
                     /locus_tag="KB902_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBB6809506.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          506 a          297 c          270 g          645 t
ORIGIN      
        1 ttcttaacgc ttgaagtggg agcttcttgg gaatagagca tacttgatag cgtatttctt
       61 tactaacagc ggtgtctctt atttaccaag ctatccccgt agttcctacg gttcttgatg
      121 attggatcta agccaatccc atagaatgta gtcttagacc ttcggtcaga atattgatac
      181 tagcattgat atcacgatca tgatgagtat gacaaacagg acaagtccat tctcgaattt
      241 caagagattt cttgccatct ttatgtccgc actctgaaca aatctgacta gacggaaacc
      301 atttatctac tttgatgatt tttcgtccat accagtcagc cttgtattgt aatttagtca
      361 caaactttga ccaagaaaca tcagaaatac ttttagctaa tttatgattt cgcaacatac
      421 cttttgtgtt taagtcttca atacagataa tatcgtgatt tttgatcatt tctgtactca
      481 acttattcag aaaatcagta cgttgattca ttactttttc atgcaatcta gctactttgc
      541 gtttttgttt ttgataattt ttagcttcaa atagattggt acctttattt ttagccaata
      601 aagcacgcct agacaatttg cgttgttcac gctttagttt cttttccatt ttggacgtga
      661 atttattatt atcaattttt tgtccatcag aaagaatcgc aaagtccata atacctaagt
      721 caataccaat tgtggaatta gttttaggta attcgataat ttcttcttta cacaacaaag
      781 aaatatagta tttaccgcta gaatgacgtg atattgtagc agatttgata atcccttttg
      841 gttgtctatg aagcttaatt cttactaatg acttcaattt aggaactttg atgaatttac
      901 tatcaatcaa agcaactgta ccattttgat tattcgttgt ataactctga acaggatttt
      961 tcttactttt gaaacgtgga aatccaacgg atttatcccg aaaaaaattc ttgtatgctt
     1021 tatctaaatt aagttgggca ttggctaaag caaggctatc aatttctttc aaaaacggaa
     1081 attctttctt gtatttagct ggtgtcggaa aagtcatttt tttagaagaa tcatttttaa
     1141 cttcttcata cgcctttttt cggtcatcaa gcattagatt gtagacctta cggacacaac
     1201 caaaagattt ggcaaagaag atttcttgtt cctctgttgg atagattctg aatttgtatg
     1261 cttttagttg ttccataaag ttcacctact ttctatttat gattgtttcc ttgattttgg
     1321 atatacttct taatcacatc aattggtgcg ccaccagttg tcagaagaca aaaactttta
     1381 gaccagaaca tttctttcca aagaaattgt ttgactcttg gaaagtcacg ttttatcaat
     1441 cttgagctgg cacttttata ggcattgatg aattttgtca attctgtttt aggttgagct
     1501 ttgaacataa tatgaacgtg gtctttatca tgattccact ccactaaagt aatgtgatac
     1561 gattctgaaa ttctttcaaa agtagttttg gcataatcag atatttcatc atcaatcact
     1621 tgtctacgat atttcgttac taaaacaagg tggtaataaa gaagaaatac tgaatgatta
     1681 tttgtatcta attccatgtt atatcaactc atttcttg
//
LOCUS       DADVXB010000232         1717 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.239, whole genome shotgun sequence.
ACCESSION   DADVXB010000232 DADVXB010000000
VERSION     DADVXB010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.239"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            646..741
                     /locus_tag="KB902_002744"
     CDS             646..741
                     /locus_tag="KB902_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6809507.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1043..1288)
                     /locus_tag="KB902_002745"
     CDS             complement(1043..1288)
                     /locus_tag="KB902_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809508.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT          532 a          337 c          279 g          569 t
ORIGIN      
        1 cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct ttaacaacca
       61 actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga taaaaagttg
      121 ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta cccttctgta
      181 tccgttggga gagtaaggct caactgcccc ctaaaaaggg ttctaaaaaa tctttaaaaa
      241 ataaataaaa taaacgcgcg cgcgcgagca aaatttcccg ccaaaaaatc acccactttt
      301 taaaataaac aggttcgcgc atgatattaa actgccaatc tagctcccta tggtcgctgt
      361 aagaaggagt gatcgctacg ctctcacatt ttacttgcag cagtcgcctt taggctcctt
      421 cgccaaaaat aattcattag ggactccttt gtggcgtcct gagagctcgt ctaagccgtt
      481 ctaagacaag attcgataaa aactatgtcc ttcgttctaa agcgccttac aggcggtcag
      541 ggcaagccct aacaacccca aggcaataaa aaacttaggc ttatttttgc ttttttattg
      601 tataattgat tgtcgcctat ccgacagtct tgcgactgga aggaggtgtg tttcgtgttc
      661 actaacttta tttgctccct tcttgttggg cttttaagcg ctttgttcag ttactggttg
      721 aataaccgaa acaagaagta aaacttaatt aaggcgactc agcccacaaa aaaagcccca
      781 gagaatccga cctctctggg gctttcgtgt gtttcgtgtt cacttatttg caatcaaatt
      841 ataacagaaa taaatattta tttcaaaaat atcctacaaa agtctaaaat ccgtaattat
      901 ttcttatatg caacatttac aaataaagtc gctctgagag ctcgtatttt tcgatttaag
      961 acgttttatt tagtttttgg tgtatttcat tggtccaagc taaaaaactc ttagaagcga
     1021 ttttagagcc atttaaaccc acttaattat attctccatg aaattcgctc catgcgtcaa
     1081 aagctgcgtc tgaaattccg ccgtcttcgt tcactagttg cattaatttt tccaacgatc
     1141 gttttctttc gggtgtcata tttttatatt ccaacaattt ttcgtctgtt aaatcgaact
     1201 tgattgcttg aattgcttgc tctaattttt ctaagttttg aaaatattcg taaggaaatt
     1261 tttccatttt ttctttctcc agtctcacaa tttttctaga aataaaatca cttctttgcc
     1321 gtctatactc tcaaaaaaaa tgtcgtttga aaaactaaat aaatttttga tcgtgcattt
     1381 ttaaatttgg ttatcgatta cacgtgcagc actccccccc cgaattttaa agagcataag
     1441 gaaacgtgta cccactttct aaaaaaagtg ggtagatagg ctgtgcctat cacgtttctc
     1501 agaaaaaaat ttgatatcac tttttcgcca tcgtgggtag cttatgtata gcattttggc
     1561 aaaaaacagc tatacaaata tagtatttgt atggtataca taaattatac ataattgcaa
     1621 aaggagattt tttatggaca ttttagttcg gaatattgat ccaaagtttg ttgcaacaat
     1681 agacaaacgt tgccaagaac tcacgaataa aacagga
//
LOCUS       DADVXB010000233         1703 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.240, whole genome shotgun sequence.
ACCESSION   DADVXB010000233 DADVXB010000000
VERSION     DADVXB010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.240"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            456..1586
                     /locus_tag="KB902_002746"
     CDS             456..1586
                     /locus_tag="KB902_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6809509.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
BASE COUNT          488 a          276 c          354 g          585 t
ORIGIN      
        1 tttgcaacgg gattctttca acttatttgt tatttttttc taaaaaatat taaagattgt
       61 taaatttcac tatttcattt caaattccat tgcctaatca ttaggaaaag tctatcatga
      121 actcgtaaat agaatatagt aataaccttg ttaggtgagg ctcctataca aacataggct
      181 gttgcccaga aacgtcgaaa gtcgccaatg ggtaaaacag aaactgttgg attaaggctt
      241 tttccaatag ctaagaatgt tttctttacg ttgtatagtg ctaaaactcg gacgatgaga
      301 tgatgctagg tcagaattct tgttcgaaaa ggtttctgac cttttcttta tatttttgtg
      361 actgacttat ttgatgagac aaactcgctc ctcacctgac aagtggattg ctgtgtgagg
      421 aggagatgcg gtgaaaaaag atcgattggt ggattttggg tccttatttg actttgtcca
      481 tgatcggtct tttagaagta tacagtgcca gttcttatcg tttattgcaa gccgatgaaa
      541 atacaaaaag tctattattg cgtcaactaa ttttcatatt tttgagttgg agcgtgatct
      601 tcttagctcg ttcagtcaaa ctacactatt tacttcaccc taaaatagca ggatacggtt
      661 tagccttatc gattttcttt ttagtattag taagaatagg gatattcggt gtcactgtca
      721 acggcgcaca acgttggatc tctctgtttg gcattcaatt ccagccttct gaactggcaa
      781 atcttttttt gattttttat ttaagctggt tttttcgtga cggaaatagt agcccaaaag
      841 atctaaaaaa accattcctg attacagtag gtataacttt tctgatttta tttcagccaa
      901 agattgctgg agcattgatg atcctttcga ttgcgtgggt catattttgg gcagcggcgg
      961 ttccatttaa aaaagggatc tatctaatcg ttactttttc tgcattgctg attggagcag
     1021 caggcggggt attatattta ggaaataaag gttggcttcc acagatgttt aatcatgctt
     1081 atgaaaggat cgcgacttta agagattctt ttatcgatag tcatggtgcg ggctatcaaa
     1141 tgacccattc gttttatgca ctatataatg gtggcatatt tgggcgggga ttaggaaata
     1201 gtatcacaaa aaaagggtat cttccagaga cagaaacaga ttttattttt tcgattatta
     1261 cagaagagct tgggctaatc ggtgcattgt gtgtgctttt cttattgttc tcattatgca
     1321 tgagaatctt ttgtttaagc agtcgctgta aaaatcagca agctggattg tttcttttag
     1381 gattcggaac tttgctattc gttcagacga taatgaacgt gggaagtatc gcggggctga
     1441 tgccaatgac tggtgtgcca ttgccatttg ttagctacgg aggaacaagt tatctgatcc
     1501 tttctttagg aatcggaatc acgttgaata tttcttcaaa gatacaggcc gaagagttgg
     1561 cgctctatcg acctgaaaaa caataaagag aaactgagaa actctcagtt tgaattatca
     1621 taaagtacaa tcttttattt ttcaagcgag aggttctttt agaaagagga attcgcaatg
     1681 aaagtatctc aaaaaatcat att
//
LOCUS       DADVXB010000234         1696 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.241, whole genome shotgun sequence.
ACCESSION   DADVXB010000234 DADVXB010000000
VERSION     DADVXB010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.241"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(74..1672)
                     /locus_tag="KB902_002747"
     CDS             complement(74..1672)
                     /locus_tag="KB902_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809510.1"
                     /translation="MLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLGYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATALTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPENAVAIAEN
                     YNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTP
                     IYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTL
                     ILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT          659 a          233 c          273 g          531 t
ORIGIN      
        1 attaaagaaa tataaaaaaa gactttttag cctgtttatg tgtacagcta aaaagtcttt
       61 cttaaataaa aatctagtga gaatgttgta cttctcttct cggttgtttt tgtttagaaa
      121 aagtaaatcg ataaagtaaa aataaaatca aagtaacgat agataaatat cttgaagcaa
      181 ttgctagttt tgtgtactga taagtaataa cgactttatt tatacctgga ggaatagtta
      241 attcagttgt gccaaactta gataattttg tttgtactag tttgccatta atagaagcca
      301 cttgcccttt ataacgataa ataggtgtcg tcaagacagt atttttatta ttcgaattat
      361 ctaattcaat tgtaagtttg ttactcataa aatgagttgt tggatttatt tcctggttac
      421 ctagtaaata ttgatcatta ttaatcatat caggatgata gattgactct ttgtttgcat
      481 aatcagtatg attgtaattt tcagctatag caacagcgtt ttcaggtgct ataagtgtta
      541 atgaatcttt gttagcatgg atagaattgc ttactcctga gagatgcaat attagtgcaa
      601 gaaacgtaaa gaccattatt ttccatgaat tatttttagt agaaaaaata taatagatca
      661 ctatactcat cgtataggct ataaataaag aagaaaaacc atttaaccgc cagacaaatt
      721 gtagactctt aactggtgta tggttaaaaa gttgccaagg aaataaattg gttgaacaaa
      781 aaagaacaaa tacaccaaga aagaaaataa ataaatcatc agcagttaat ttttttataa
      841 aaataaaagc accaatcaat ccgagaaata agaataatcc aatagtatag ttgttatagt
      901 tattatttaa aatatgtgtc agcatatcac taggagccat accacttaat tcttttccca
      961 gtgggacttt caattcttgt gctctagatt gttgaataaa aggaattaag aatcccgcac
     1021 ttaaaaaaaa ggtgagggcg gtagctttta aaagacttaa gagtctagcg attttttggt
     1081 cccaaaaata aaaagaaaga aacaacgttc ctccaataaa tacagaaacc atagcgacag
     1141 aaagtaaatg agtatacact actagcgtca tgccaataga caaccagtac catttttggt
     1201 aatctctaat ataaatttcg taacacccca ttagtatcaa aggcaaaaat gttaaagcga
     1261 cagcttctcc caatgaagca cgatggaata tgtcaatggc acgataggcg gaaaatgtat
     1321 aaataatcga aaataacagc gaaatataac gattgttttt tatttgtttc atagaaaaat
     1381 aagaaacgac cattgttaaa aaagtgataa aaaaatagta gatattataa cctaaaacaa
     1441 gatttcccat cattttataa aataaaaaag ctggataaag agtaagccat ggataaaaaa
     1501 tattcatcat tgttccatga tgatcgaagt tattgaagtt tactggagaa ctccatacat
     1561 tatctagtcc tatgattcga gataaatgaa agtaagtatc ctgattgaca ctatgataga
     1621 ttcccttaga catgaataga gggatgacgt aagcaaaact tagaaataac ataaaaatga
     1681 tatctattat ttggtt
//
LOCUS       DADVXB010000235         1624 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.242, whole genome shotgun sequence.
ACCESSION   DADVXB010000235 DADVXB010000000
VERSION     DADVXB010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.242"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(134..1600)
                     /locus_tag="KB902_002748"
     CDS             complement(134..1600)
                     /locus_tag="KB902_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBB6809511.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          530 a          344 c          303 g          447 t
ORIGIN      
        1 aaaaaatctg agccagaatg tggttcattc tgactcagat ttgattttgc acaactcatc
       61 agtccttatt gacaaagagc ccaaaaaaca ggaactgctg caaataagca attcctgttt
      121 ttatgttcat tgattaatga atagagccca ttagtttttt gattggttct ttcacagtaa
      181 atagcaagat accaccgacg attgctactg caccgataat accgaagtaa gcagattctg
      241 ttcccggtgt gtagaagcgt gcaatttgtg cattgattgc ttgtgaagaa gcatcagcta
      301 agaaccaaat agcgattgtt tgtgattcaa atgctcgtgg tgctaatttt gttgtcacag
      361 acaaaccaac tggtgaaaga cacaattcag caataaccac gatgaagaaa cttcccaaca
      421 accacaatgg acttactttt ccacttgtac cataaagcat acccggcaac atcaatagca
      481 agtacgataa tcctgcaaat aaaagtccaa gagagaattt cactactgta gatggttgac
      541 gttcaccaag tttcgtccac atcgttacga atactggtgt cagaataaag atgaaaattg
      601 gattcaatga ttgataccag cttgcttgga tcgttacacc aaatagcgta gattgtgtac
      661 gttcactagc aaataaagct aagatagatg aaccttgttc ttgtaatgac cagaaaatga
      721 ttgctgcaag gaataatggg atataagccc atactcttgg tttttcttca gcagttacat
      781 cttttgaagt cagcattttg ataaagtaat acaacggtaa gataatcccc aatacactga
      841 ttgtattgac aaaaaagtca attgtcagat gaccagttag ttgtgccccg ccgaatactg
      901 cagcgataac aacaagtgcg atgatcaagt tacggatgaa tcctttacgt tcttcagttg
      961 tcaaaggatt cggcggtgtt gtacccactc cgtctaatgt cttgcgtcct tggatgatgt
     1021 attgtaataa tccaaagaac atcccaatag cagctaaaga gaaccctaaa tgatagttat
     1081 attcttgacc gattgtacca acgattagtg gtgctaataa tgcccctaag ttgacaccca
     1141 tgtaaaaaat cgaaaatcct gcatctcttc gcaagtcagt ctttgaataa agatgtccga
     1201 ccatgccaga aacatttggt ttcaaaaagg cggttccgat aataatcaat gccatcgaaa
     1261 caaacaatgt acttacacca aatggtaaag ccaagacgat gtggccaagc ataatgaaaa
     1321 ctccaccgaa gaatacagtg cgttttgctc ctaacactcg gtcagatacc catccgccga
     1381 cgatactaga catgtagatc aaagatccgt agatcgacat gatagctaat gctgttgctc
     1441 gtggtaatcc aagtcccccg ttggcaactg tatcgtacat ataatagata agtaatgcac
     1501 gcataccgta ataactaaat cgttcccaca tctcagtgaa gaacaaagtt gacaatccct
     1561 tcggctgccc gaagaagccc ttgtcttgct gtttttccat aatctatacc ccaattcttt
     1621 aaat
//
LOCUS       DADVXB010000236         1584 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.243, whole genome shotgun sequence.
ACCESSION   DADVXB010000236 DADVXB010000000
VERSION     DADVXB010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.243"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..607)
                     /locus_tag="KB902_002749"
     CDS             complement(<1..607)
                     /locus_tag="KB902_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809512.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELI"
     gene            complement(707..1216)
                     /locus_tag="KB902_002750"
     CDS             complement(707..1216)
                     /locus_tag="KB902_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBB6809513.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
BASE COUNT          458 a          324 c          201 g          601 t
ORIGIN      
        1 taattagttc atcgcccaat aatctctcca gtttcttagc atctcctgac tcaaccggaa
       61 ttatccaagc ccagtctaaa taatttttta aaatctcatc atattttgca aatatttcat
      121 tgccatattc cgtccttaaa attatatttt cagtgccaga caagtgattt atattgagtt
      181 gataaaaaag atctccatct aaaaaaatat cattagaaga agatttcccc acagtaatga
      241 ccattccatc agctctatgt gttacataca aataattgta tgacctcatt tcacctaatg
      301 aatcaattat ttcttgccct ttagctctaa tatattgatc tctattacct atctcactct
      361 tatttaacaa aagttttttc atgtcaaatt taatcggctg ttttattttt gtaaattcgc
      421 ttctactact aatccaatcc gagattaatt tttcaacatg tcccagagta aactctgatt
      481 tattcgctaa atactttttt tgttgtatta aagacatctt tccccgaagc tcaaaattga
      541 gcctacatcg attctctatc tcttcaaaaa gcatcttatc ttcatcattc ttatattcat
      601 cattcataaa accaatccag ctcctcgatt aagataatat tttaatctca tacaaaaact
      661 agctctcatc aaaacaacca ttgttttgat ttctcatgaa atttctttat acttttctcc
      721 gattataaat tcctaacccc ttgagaaaat tacgcatata tttatctccg caaggcttaa
      781 aatttcgttg gccttctttt ctcaaaaatg ccccgatttc gccttttgat ggatagattt
      841 ctgcctcagc aaaaacgtct aaaatatcat cagtggtcat agacaaggcg atttttaatt
      901 tttttagcaa cacattgttg atatatttga tttccttgct tttttgcggc gtgtctacta
      961 tcggcttatc tttttgcgga ccacgcgcca agagaatcag gccatttagg aatgcgtcaa
     1021 aaacttggtt gttgatggtt ttttcataca cattattttc tgcattatct ttgttcttat
     1081 cctgtacttt ggtcagtacc gcctgagctt cttctttagt cagtggtaca ccgcctagct
     1141 caaaagcttt aatcaaatcc gtatctttca aatcaatcgc ataacgcaat cgcaataacc
     1201 tatcattgtt attcatttgt tcctccgaag tatttagtct ttactttctt acgtactttt
     1261 tgtcttgcta agatttttag gatcaatgat aaaaaccgca tcacttatga taaggcgctg
     1321 ggtaatgagt gaatgatatt tataaatcac tggatattga agtatattct gttttctcaa
     1381 cttatttagt cagatttttt aatgaagatt ttttgagtaa aatttctata attcctactt
     1441 attgaaaagt agtttgtagt gctgcttcta cctctctcat ctgttctaca aattccaaat
     1501 aacttgacgc agcttgcgga atgaaaaaat gatatgtgaa tatttctcct cctagcccgc
     1561 ttaatatgcc tatttttttc gccg
//
LOCUS       DADVXB010000237         1525 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.244, whole genome shotgun sequence.
ACCESSION   DADVXB010000237 DADVXB010000000
VERSION     DADVXB010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.244"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            76..1245
                     /locus_tag="KB902_002751"
     CDS             76..1245
                     /locus_tag="KB902_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6809514.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT          546 a          273 c          246 g          460 t
ORIGIN      
        1 ataaatgtta tcaagataca agctatttta gctttattct ttctgtaaaa aagaaaggag
       61 actaaataaa ctattatgaa aaaaggaaaa catgctaaaa aaagaaaata ttcattttta
      121 atgatcgttg tcgtgttgtt tagccttagt gcgttctcta caggaactat tcttggatgg
      181 caattttaca ataatgaaca ctctcagata gttgcccatg ctcaatcagc tcaaaaaaag
      241 ttgatactga ctaccaatga acaacagctc gttgaaaaaa tcgatcaact attaagaaaa
      301 aatgattata ttggctcaat ttacgtaaag aaaaataatc gcatcatcat ggaaaaaggc
      361 tatggctatg cgaataaact cacgcaacaa ccaaatgatc cttctcttta ttatcagatt
      421 ggttcggttc aaaaagcatt gactactctt ttgattttaa aacaagtcga gcgtgggcac
      481 ctttctttag atactaagct ggctcaattc tatccacaaa ttgctggcag ccagcaaatt
      541 actatccgtg acttgctgta tatgcgctca ggcttgcacc gaactgcttc tccaaccata
      601 ccgatgactg atgaagaagt cgttcaattt gcgattcagc acttaaaatt tacagattat
      661 cagacctctc attatgattc attgaacttt accatattga ctggaatttt gatcaaatta
      721 acaaatcaac cgtatgaaaa attattgacc gatgatatca tcgaaccttt aggattacag
      781 catacaaaat tttatgacca agtcaaaaat tcatccaatc atgcactatc ctatcaaatg
      841 tctaaagagg atgattactt taaaccactg acagaatctg aaacagagat ccataacgaa
      901 ttagggactg gtaatatcag tatgtccgtc tatgatttaa atacgctgtt tacacaagtt
      961 ttatctggaa aactagtttc caaagactta ctcttctcat tatggcgtga aaatgcgaat
     1021 ggacatccat atagtggtgg ggtatatagc ggagataatt atatcctgtc gcaaggaaat
     1081 atcgactctt ttgatacatc tgctatattt agcaaagatt cacaggatgc tatcatcatg
     1141 gaaagcaata taaaagctga caaaactatc aaactgccta ctgctgatct aagaaaccaa
     1201 atctatgacc tgatggaagg aactactaag ttggcaaata gctgatatga tgaaaagata
     1261 gcaaatacta cttctttgaa tagcatttgc ttaaaaaaag tactcgacta aacgtaggaa
     1321 agagtgtggg acaaatctaa aaatcaattt ttgctacaga ctttaattcc aaataaacag
     1381 aacagaaaga ggtgttcttc tttctgttct gtccaaatta ttctaagatt tctctttacc
     1441 aacattattt gacaaagggc ctattaaatc taaaatagta tctttagatt gctaaaatat
     1501 gtgctagcaa atcattcatg gcttg
//
LOCUS       DADVXB010000238         1503 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.245, whole genome shotgun sequence.
ACCESSION   DADVXB010000238 DADVXB010000000
VERSION     DADVXB010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.245"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..626)
                     /locus_tag="KB902_002752"
     CDS             complement(<1..626)
                     /locus_tag="KB902_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809515.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPR"
     gene            914..>1503
                     /locus_tag="KB902_002753"
     CDS             914..>1503
                     /locus_tag="KB902_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6809516.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELR"
BASE COUNT          526 a          217 c          285 g          475 t
ORIGIN      
        1 tttctaggaa agtgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattaaaa aaaagaaaaa gtattggcaa cagaaggcgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattctt taattaagaa
     1261 gaattatgga catttagaga agtttgaata taaggatcta tcggttaatt ttaatagcta
     1321 tacagctaaa ataaatggtg aagaaataga tgtaaatgca aaagaactag aagtattaaa
     1381 atgtttattg gataataatg gacaagtgtt aacaagaatg caaattattg attatgtatg
     1441 gaaagatagc gaagaaactc cttatgatcg agtaatagat gtatatataa aagaacttag
     1501 aaa
//
LOCUS       DADVXB010000239         1500 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.246, whole genome shotgun sequence.
ACCESSION   DADVXB010000239 DADVXB010000000
VERSION     DADVXB010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.246"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            600..893
                     /locus_tag="KB902_002754"
     CDS             600..893
                     /locus_tag="KB902_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBB6809517.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT          534 a          225 c          258 g          483 t
ORIGIN      
        1 attgaaacat ccatctggaa tttatctttt ttgctgcttt gctcataaaa gtctgcatat
       61 tcatcactga tattttttct aataaagtct tccatcataa aaatcacctc aaaacgatta
      121 tacgaactta cgttctcgtt gtaaagcgat atttgagggg caaaaagggg gcaaaaatac
      181 gtttatcttt gatatatctc agattgaact tagtgtttat tatatgtcgg tattgttgat
      241 ttatagctgt tttgagggta ttagatacat aatagaatat agtggttttg tttacgtgca
      301 ttacacggaa aagctgctcg tatcaaagaa atccgtcgtt aatcattgtt atcagactga
      361 gaaagaaccc ttggtattca agggttcttt tttcttagca tgtaatttga acaccctgat
      421 ccagtttttt ctttaattat tggtagggga gaataatgga ttagaataaa tctacctata
      481 agtagtagta aaaaaaagag cactatgata atatctttct taagagtaac cgctttaata
      541 aaaaatccag aatattctaa cataaatgga gtattcttag aatcaaaagg agaaagaaga
      601 tggtttatac ttatacggag caagaaaaga tgaaagtttt agacacattc atgaatgatg
      661 gaaaagtaaa acaagtacca agttcaacaa aaaagaaata catcctattg aaagaagtct
      721 tgaaacgctt tgaccatgga gtgacttata cagaaacaga ggttaattcg atactgctga
      781 acgtattttc tagtggcgat tatgtcgaac aaagacgtta tctaatcaca tttggctttt
      841 tcaaaagaag ttcagacggt cgggcatatc agatgatggg aattgaaaat tagaagtttt
      901 aatttatact cattgaaaaa agttcaagta tgcgatattg gttctacacc gcatacttga
      961 actttttttg tcatctgtat ctataataca aagccaagaa cgttattcaa aatatggata
     1021 gctatgataa aagctaatga gcgattcgca gttaaataag caatcgtcag taaaatcgtt
     1081 ccaggagcgt acatgaaaaa atcaattgga tgcgttacat gaataaagat aattctcttt
     1141 tatttgtacg aataaatacc aaaacgtacc tcctaaaatt agattttgga cagatgccct
     1201 ttaaaaagat aacaagattt cgttcttgaa acaatatata tgcttttatt ccaatgaggt
     1261 tgtgaaaaca gtattttgtc ctgagcgtta gaaaattgaa aatggggaat agcaactcgt
     1321 actttaccat tttttaagtg aatacaagat cagctaattg aacaccgttt attcgtgatg
     1381 agggacacaa cactgcagtc gacacatttc tcttttatgt tcaaagataa caaatattta
     1441 aaacaaagaa aaatagtaga taatcccgtc ctaactcttt tattcttccc tcatagcttc
//
LOCUS       DADVXB010000240         1495 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.247, whole genome shotgun sequence.
ACCESSION   DADVXB010000240 DADVXB010000000
VERSION     DADVXB010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.247"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..311)
                     /locus_tag="KB902_002755"
     CDS             complement(<1..311)
                     /locus_tag="KB902_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809518.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWGHVYLIHLWKQPRKPEYIYVIEDGLIDALEEYDRDNLIDISYYGQGKK
                     Y"
     gene            complement(487..1212)
                     /locus_tag="KB902_002756"
     CDS             complement(487..1212)
                     /locus_tag="KB902_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6809519.1"
                     /translation="MQELVILKNKEAVTTSLQVADSFEKKHKHVLEAIESIKRSVENS
                     ANVEDGSNFGQMFVEGNEPDSYGRSRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
BASE COUNT          388 a          289 c          231 g          587 t
ORIGIN      
        1 atgtattttt tgccttgtcc gtaataagag atatcaatca agttatctct gtcgtactct
       61 tctagtgcat caatcaagcc atcttcgatg acatagatgt attcaggttt tcttggctgc
      121 ttccatagat ggataaggta gacatgtccc caaatactca caaaatttcc caaatcgtct
      181 tgatcacatg ctagttcttc atccgtcaaa agattacgtc tgatttttcg attgcttgtt
      241 tccttgatat tcgatttgcc ccaactagga tcagtcaaat attgatctag agtggaaagt
      301 tcttttttca tgtggtaaca tctccttaga tgtattttgt ttgcgactca atgcttgccg
      361 gcggagtcgc tttttatttg ttgccatgct ttttgcttat caatatgttg ttggcttagg
      421 atgtttggtt tattgtgtct ccaccagcga ttagcaatta ttacgcctat ttttagcgct
      481 tcagctctat tcattttcat caccgaaaag tctttgttgt ctgttcagtt gatcgatttc
      541 catgcggatc gcagtttctg gtaaccacat ttcaataaat gaaacagcat catcgaatct
      601 cttacgaggt aactcgccat atcttgggat tgaaaaggta cgtttaaatt cagaccaaaa
      661 ttttgagaat acttttttgc tgatttcttc ataagctcgg ctttcttttc cccctagaac
      721 ttccataact ttcatatttc ctttttgctt aatttcaaac tcttgttgtc cgctaattcg
      781 catagtatct ttaagcatgg aaacatcttt tttaacatct ttcatttctt ctaattgata
      841 gatcatcatg tcttcaattg tttgaggaac agtattcttc cgaataacat cttccatttc
      901 gttgaaagct tcaataaatt ttagtttgaa atttattgct ttacttccag tgaatcccat
      961 agctagcaag gaaaatccgt ctctattcat gaaataaact ctccgacttc ttccgtatga
     1021 gtctggctcg ttcccttcca caaacatctg tccaaaattg gacccatctt caacattggc
     1081 cgaattttcg accgatcttt ttattgattc gattgcttct agcacatgct tgtgtttctt
     1141 ttcaaaactg tctgcgactt gtaagctcgt agttacagct tctttatttt tcaaaattac
     1201 taattcttgc attttttctt ctctcctttt gatataattt aggtaaaaaa tggtggtgaa
     1261 aatatttgaa aaaattgcta tatattttac ttttttcaac ctttgcaatt gttgcattat
     1321 tgttgctttt cgaacatctt aaaagagtaa acttggatgg aactttgtta gaagagcaaa
     1381 ttgcgattct aaatactccc aaattactaa ttgtattctt ttttatgtgt atgttatccg
     1441 ctctgatatt tatgttctat atatcaactt tttgggtata caaggagatt aaaaa
//
LOCUS       DADVXB010000241         1482 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.248, whole genome shotgun sequence.
ACCESSION   DADVXB010000241 DADVXB010000000
VERSION     DADVXB010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.248"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            132..506
                     /locus_tag="KB902_002757"
     CDS             132..506
                     /locus_tag="KB902_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6809520.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="KB902_002758"
     CDS             complement(620..1249)
                     /locus_tag="KB902_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6809521.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="KB902_002759"
     tRNA            complement(1383..1455)
                     /locus_tag="KB902_002759"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
BASE COUNT          501 a          225 c          260 g          496 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga ta
//
LOCUS       DADVXB010000242         1476 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.249, whole genome shotgun sequence.
ACCESSION   DADVXB010000242 DADVXB010000000
VERSION     DADVXB010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.249"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1192
                     /locus_tag="KB902_002760"
     CDS             <1..1192
                     /locus_tag="KB902_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6809522.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDL
                     TDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDN
                     RSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIV
                     VVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPNGSQ
                     YHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSEKAVSKDN
                     KTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGLLGYKNRK
                     KENE"
     gene            1326..>1476
                     /locus_tag="KB902_002761"
     CDS             1326..>1476
                     /locus_tag="KB902_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6809523.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIK"
BASE COUNT          587 a          209 c          313 g          367 t
ORIGIN      
        1 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
       61 accagacgca tctgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      121 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      181 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      241 tgacgccgat aaatatgagc caacagtaga aggcgaaaaa gtagaagttg gaggcacagt
      301 agatctaaca gataatgtta ctaacttgcc aacattacca gaaggaacaa cagtaacaga
      361 tgtcactcct gatggtacga ttgataccaa cacaccaggt aattacgaag gggttatcga
      421 agtaacgtat ccagatggta cgaaagatac agtgaaagtt ccagtagaag tgacagacaa
      481 tcgttccgat gccgataaat acaatcctga aggacaaaaa gtgactacag acttaaataa
      541 agagccagac gcatctgagg gaattaagaa caaagaagat ctaccaaaag gaactactta
      601 tacttggaaa gagaaagtag atgttagtac agctggaaac aaaaaaggga ttgtagtagt
      661 aacatatcca gatggatcta aagaagaagt agaggttact atttctgtag aagataaaaa
      721 agcaccgaat aaacctcaag ttgatcctat tacagagggt gaccaaattg ttactggtaa
      781 aactgaacca aatgcagagg tgacagttac attaccaaac gggagtcaat accatgggac
      841 agctgataaa aatggtaatt ttacagttaa agttcctaaa ttagaggcag gaacaaaagt
      901 gatagtaact gcaactgatg aatctggtaa tactagtgaa cctactaatg tagttgtttc
      961 ttcaaacgaa aaagacagtg aaaaagccgt tagtaaagat aataagactg acaatcaagg
     1021 tagcaagcaa aacaaaaata gaggcaaaag cagtcctcaa aagcagtcct caaaagctta
     1081 tcctaagacg ggagagattg atagtaatat ctttactatt agtggtggtt taatcctgtt
     1141 aggaacttta gggttattag ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa
     1201 tttcttaaat cttctctgaa aagaggaaga atctttttct tcctcttttt gttttttatt
     1261 ttgggagata ggttgttagt taaaaatgaa gatacttttc atagaaggga aaagaatgtg
     1321 attaagtgaa aaaaatagta attattggat caaaccattc ggggctagct gcagctcgat
     1381 ttctaaactt atgtgattca aattatgaag ttattctgat agataaaaaa tcagaaatta
     1441 gttacttaga atgtgggaca tcgttgttca taaaaa
//
LOCUS       DADVXB010000243         1464 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.250, whole genome shotgun sequence.
ACCESSION   DADVXB010000243 DADVXB010000000
VERSION     DADVXB010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.250"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            208..1215
                     /locus_tag="KB902_002762"
     CDS             208..1215
                     /locus_tag="KB902_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6809524.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1227..>1464
                     /locus_tag="KB902_002763"
     CDS             1227..>1464
                     /locus_tag="KB902_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6809525.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQ"
BASE COUNT          577 a          181 c          259 g          447 t
ORIGIN      
        1 attacgaata aacaattatt tgacacaaaa aaaatatgta tcataataat ttttgtatca
       61 attttttctt tgatacttca tattttaatc aatcaaatgt tgattcgtta cgttttgaca
      121 tcattattga taattagttt agttatatat tttttaaaga ttaagaatcg aattatagat
      181 gactataatt cataggagga gatataagtg tttaaaggaa aaacaatatt agtaactggc
      241 ggaactggtt ccattggaag tgaaattgtt cgtcagcttt taaaatatga accaaaagct
      301 atcagaattt atagtagagg tgaagaaaaa caattttata tgcaacaaga gctctcaaat
      361 cacactaatt tgagattttt aattggtgat atcagagact ctcaaaggat tgattatgca
      421 tgtcgtgatg tggatattat ttttcatgct gccgcaatga aacacgttcc agcaagtgaa
      481 tataatccta tggaagctgt aaaaacaaat gtgatgggaa ctcaaaatgt aatagatgca
      541 gcgatcaaaa ataatgtaaa acattttgta ggtatcagta cagataaagt agtgagtcct
      601 actaacacca tgggtgcgac aaagttattg agtgaaaaat taataatagc tgccaatcag
      661 tataaaggaa aaacagaaac aatattttct tgtgtaaggt ttggaaatgt catggggtca
      721 agtggatctg ttattcctct ttttagtaaa caaataaaaa acaataaaga tattactttg
      781 acagatgttg atatgacacg atttatgatg tcaataccgg atgctgcaag attagttctg
      841 tctgctgcta tgaattcaaa atttggagaa acatatgtct taaaaatgcc ggcaatcaat
      901 attttaactt tagctcaatc attaataaaa atatataatg atacacatga tgaaaaatat
      961 agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa aattatatga agagctaatg
     1021 actacagacg aaattgaacg ctcatatgaa aatgataaaa tgtatatcat tccaccacac
     1081 tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa ttaaaatcac tgcatactct
     1141 tcagatgcaa cagaattaat gagtggacag gaatttatta gaatcgcaaa agagaataat
     1201 gtcgtgactt ggtaaggagt tttatgatga aatcagaagt atatgtaatt gcagaaattg
     1261 gtgtaaacca taatggaagt ctagatttag ctttagaaag tattgataaa gctaaagaat
     1321 gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa taagctagtt tccaaaaagg
     1381 ctccaatggc aaaatatcag aaggataatc ttaaagagga cagttctcaa tttgaaatgc
     1441 taaaaaaatt agaattatct caat
//
LOCUS       DADVXB010000244         1436 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.251, whole genome shotgun sequence.
ACCESSION   DADVXB010000244 DADVXB010000000
VERSION     DADVXB010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.251"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(26..328)
                     /locus_tag="KB902_002764"
     CDS             complement(26..328)
                     /locus_tag="KB902_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809526.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(548..914)
                     /gene="ssrA"
                     /locus_tag="KB902_002765"
     tmRNA           complement(548..914)
                     /gene="ssrA"
                     /locus_tag="KB902_002765"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1085..>1436)
                     /locus_tag="KB902_002766"
     CDS             complement(1085..>1436)
                     /locus_tag="KB902_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBB6809527.1"
                     /translation="NTVNMLLILSQSGDEYYHEHFPELTFYRNGPYSIDTVKKGISKG
                     AGVKRLQKELQLEKVPTFGFGDGPNDFALLEACDNKIAMGNAYDGLKELSTFITKKNT
                     EGGIVHALKYFDLI"
BASE COUNT          459 a          278 c          242 g          457 t
ORIGIN      
        1 ggctaccttt tttaggtagc ctactttaat ctttatacct ttctggatca acgaaagtat
       61 acttcaaata gtcataacgc cgatgatcgc tccgtgcgtc tggcacatca gtcacgatat
      121 caaacaaaaa atacacatct ttcttcattc tggtttttgt tgccggaatt ttaaagtagt
      181 tcttattaga gtaatagaga ttgattaata agctatcttc gattgctaaa aagaaaactt
      241 ctgaatccca caccttataa aaatctttga caaatctatt cgaaggatca aatttaaacc
      301 ataattgtgt ttttccttcc atcaacataa tgttcacctc aaaaagagta tacgaactaa
      361 tgttcttttt gtaaagtagg aatatcattg ataatatgga tggaacatat atattaaaaa
      421 gtgttctttt tgaatgctat tttgaatgcc attttcattc atttaacgaa aatctgcgaa
      481 aataaaaaat gctcaaaccc ttataaaata aggatttaag catctagcga aatctgctga
      541 aatctcacaa tggagacggc gggagtcgaa cccgcgtcca aacacatcgc cacttaaaaa
      601 tctacgttca tagtcaactc atttaaggat tcactttaca gcttgccgag tgacaggcat
      661 tctgtatcgc tagtctgatg ttctcttttt caacttacag acggaaagtt gaaacgtatc
      721 ccactaaagt taggaccctt actcgagcac atgggcgatg ccgagaggat ctacgctaac
      781 tgtttttagg cagctaaagc gtaagagttg ttttcgtttt tagcagttat atttaactgt
      841 aacgttttta cgtagacgta acctacgaaa cgcaattcaa gctcgactgt gcctgtcgaa
      901 tccgtaacgt ccccgttagc taacaagggt tacgtgtatt tttcatacaa aattagtata
      961 gcatatattg ggataaattc aataaaaaag cgaatcatat cccattattt atataataac
     1021 tgcccctttc ttaagaaaaa ataagcgatt ttcttaagaa aagaggtagc ttcaaaaaaa
     1081 gatcttaaat cagatcaaaa tacttcaatg cgtggacaat tccgccttct gtatttttct
     1141 ttgtgataaa ggtagaaagt tcttttaatc cgtcataggc gttgcccata gcgattttgt
     1201 tgtcgcaagc ttccaacaag gcaaaatcat tcggaccatc gccaaatcca aaagtaggaa
     1261 ctttttccag ctgaagttct ttttgcagac gtttgacacc tgcccctttt gagattcctt
     1321 tcttcactgt atcgatcgag taaggaccat tccgataaaa agttagctca ggaaaatgtt
     1381 cgtgatagta ttcgtcacct gattgagata agatcagcaa catatttact gtgttt
//
LOCUS       DADVXB010000245         1427 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.252, whole genome shotgun sequence.
ACCESSION   DADVXB010000245 DADVXB010000000
VERSION     DADVXB010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.252"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(943..1356)
                     /locus_tag="KB902_002767"
     CDS             complement(943..1356)
                     /locus_tag="KB902_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBB6809528.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          525 a          236 c          209 g          457 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaat
//
LOCUS       DADVXB010000246         1409 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.253, whole genome shotgun sequence.
ACCESSION   DADVXB010000246 DADVXB010000000
VERSION     DADVXB010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.253"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1359
                     /locus_tag="KB902_002768"
     CDS             <1..1359
                     /locus_tag="KB902_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBB6809529.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
BASE COUNT          466 a          255 c          299 g          389 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgta
//
LOCUS       DADVXB010000247         1394 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.254, whole genome shotgun sequence.
ACCESSION   DADVXB010000247 DADVXB010000000
VERSION     DADVXB010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.254"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            88..984
                     /locus_tag="KB902_002769"
     CDS             88..984
                     /locus_tag="KB902_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809530.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            1033..>1394
                     /locus_tag="KB902_002770"
     CDS             1033..>1394
                     /locus_tag="KB902_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809531.1"
                     /translation="MKPNLSLTSERIRKIIESKGLTLERFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSVDWIKWGTLEEYIASYLIDSGYELYIKDFPEIPYKVFKD
                     IQEKYSDTFSLDKDYELL"
BASE COUNT          526 a          197 c          265 g          406 t
ORIGIN      
        1 cctagttttt atgaatgacc gttttgtaaa tctgattgaa atagatttat atgatttcgg
       61 tatatgatat acattaggag gtgtcgaatg gaaataaatc tttttgaggc tggtaatcga
      121 ataaagcaaa tacgagaaaa acatggatat actatggcag acttaggtaa actggttgat
      181 gccaatagtc ctagcacaat taacaattgg gaaaagggaa ataacttacc taatagaaag
      241 cgtcttgaaa aaattgcact attaggtggt acttctgttg aatggataaa gtatggagat
      301 ttttccgatt atgtttatcg cttgacacaa aatatagagg aaaaaattct taaagagtac
      361 ggagagacta cactgaacaa ctaccgtgaa gctcttctag atgaacttac gattgaaaaa
      421 atcacatacg aagaagatac aaagatatta gcagctgccg aaaaaatcaa tacacaaaat
      481 atttttcagg aggtgaagta catgtattct cctgatgaag attatcgaaa tatagaagtc
      541 aaaccagatt taggactgac tgatgacaac aaaaatatta aaatgattgg acaacgtata
      601 aggaaaataa gaaaaaaaga gaatattaca ttagaagaat tcggcaaact attctctcct
      661 acagctgata aagctgttat aagcaactgg gaaaatggta aaaaccttcc taactcagaa
      721 agaattaaaa agattgcaga aattggcgga gtttctgaac tttatcttat gacgggtgtc
      781 gattcaagcg tagcagaatc aatgtatttt ctatctgaag tagcattgga tgctttggaa
      841 cgtctgtcaa ttgaggaagt caatagaata attgaaagct tcgccggtta tcttaatgtg
      901 atttcaaaaa ttgatgatcc agataagcga gaaatatctc tcaatgctat ttgtcaacta
      961 tcacttctcg ataaaatggg ttgattcaca aaaaatattg aaagattact ttactcacga
     1021 ggaggcttag ctatgaaacc taatctatcg ttaactagtg aacgtattag aaaaattatc
     1081 gaatccaaag gtctgacatt agaacgattc ggtgatttaa ttggcgacac accaataagt
     1141 tctgttaata attggcttag aggcgtgtct ttacccaata aaaataggct tttaacaatt
     1201 gcaaatattg gaaacactag tgtagactgg attaaatggg gaactttgga agaatacata
     1261 gcttcatacc ttatagattc aggttatgag ctatatatta aagactttcc agagatacct
     1321 tacaaagtct ttaaagacat tcaagaaaaa tatagtgata cgttttcact agataaagac
     1381 tatgagttat tgaa
//
LOCUS       DADVXB010000248         1341 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.255, whole genome shotgun sequence.
ACCESSION   DADVXB010000248 DADVXB010000000
VERSION     DADVXB010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.255"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            240..1280
                     /locus_tag="KB902_002771"
     CDS             240..1280
                     /locus_tag="KB902_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6809532.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          536 a          184 c          214 g          407 t
ORIGIN      
        1 tttaaaacta aattttattc atacgttttt ctggtagtat ttaattataa ataatattta
       61 tttaaagtag ttcttaatga ctttaaaggt agtacataat tcattttatt tctgatttta
      121 ggtagtattt aattaaaaaa cagttttaat gcgtttgcat tttttattta tctttgctat
      181 tttcgaaaag agtaggtaat tttacataaa taaaacaacg tgaaagtaga ggatctacaa
      241 tgactgattt taaatttttt aaggcggata gagtttacaa cgaattattt tatcaatttc
      301 caaaagtctt tattgtttct gacgaataca aaaaaatgaa agattcaact aagattgcct
      361 atatgctttt aaaagcaaga ttagagatcg caatcagcaa acggcaaatc gatgaagaag
      421 gtaatgttta ttttacttat acgacaaatg aactatgtag agtattaaac tgccaaaaac
      481 aaaaagcgat agcaatcaaa aaagagttgg aatcctttgg tttattatta caaaagcaga
      541 tgggatttaa caaacagtta gggaaaaata atcctaatag actatatcta gcagaattaa
      601 aagtctcaga aaatgatatc tacttactcg aaaaatttga tagagagaat agggaaaacg
      661 ttgataaatc agagggtatg aaaatcatac ccaccctcga cgaaaaatca gacgctgaat
      721 cccttggggc tcaagagggt atgaaaatca taccgtgcca aaacgttgat aaatcagagg
      781 gtatgaaaat cataccagaa cttaataata atatattaga cactaataga cacaatatag
      841 acactgaaaa agaccgccta caagatcaat tgttgttaga caattttgag acaattatga
      901 caaacgacag cattgctacg tttgtccctg aacgagtatt aaatttgata aaaacatttt
      961 cttcaagtta cagtgaagct caaaaaaccg tccagactat tcataatgca aagaaaaaag
     1021 ctgaaataga aagtgatatt tcgatagttt ttgaagaact cgatagttat tatgtcaatg
     1081 cagaacaaga attatacacg acactgttaa aagcctatca aaaattaaaa accgaaaaag
     1141 tcgaaaatat ccagaacctg atttttgtct atgtaaaaaa ttggtttatc gaaaaaccaa
     1201 tagctgctaa agtatcaagt gaaaaacgtt tgaattatgc aagctcccca agcactatta
     1261 cgaaagactg gttagagtga aactttactg acaaagtgat tgttgcttca tggagtaaca
     1321 ttaaaattaa aaatttttta t
//
LOCUS       DADVXB010000249         1309 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.256, whole genome shotgun sequence.
ACCESSION   DADVXB010000249 DADVXB010000000
VERSION     DADVXB010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.256"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            383..715
                     /locus_tag="KB902_002772"
     CDS             383..715
                     /locus_tag="KB902_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809533.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            625..828
                     /locus_tag="KB902_002773"
     CDS             625..828
                     /locus_tag="KB902_002773"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6809534.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            1012..1167
                     /locus_tag="KB902_002774"
     CDS             1012..1167
                     /locus_tag="KB902_002774"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6809535.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
BASE COUNT          469 a          232 c          231 g          377 t
ORIGIN      
        1 acgaatgatt ttaattatta acgtttttta attcgttttt agcttaaaaa taacttttgt
       61 cacagtctca ctcctaaaat tactttattt acgtacgaag tgggcaggag gtcgaatcca
      121 gaactgggcc atggtacttc aacgaggact tctcctctag aattgaaaag catgcgattt
      181 accttccgta acgacggtag atttattcaa ctatgtgtcc aatcaaaatt tgtctgattt
      241 caaaaatagt caagagaatt ttggttgtta aaaactctta tctatcaact tccacagttt
      301 agttgacaaa ccctgatact aagttgggct atgatacact tttcttgact atcagttacg
      361 ttaccggaag gaatgaactc tattgaaaaa aacatatgat cgtaaattta aactaaagat
      421 ttcacaggat atccttgaga aaaaagtaac taccaagaaa attgctgaag aatacaatat
      481 ctctcgtcca acaatttccc gatgggtttc agaatatcgt cgatacggga aaaatgcttt
      541 tgctggacaa ggaaaaagat tacctgataa agcagatttc tacattcttg aacaggaaaa
      601 taaacgacta aaagaggaag acgagtgttc tacgaacaca aagatcgata cggatctcca
      661 gggatcactc aaaaacttta cgatgaagga atcgaaatca ataaacgtgt tgtagctgtt
      721 cttatgcgtg aaatgaattt atgcacaaga ggatttcatc gacgcaaatc ttctcatggt
      781 agagaaaaaa caatcaaaga aatggtaaaa aaaatgttga atcgataatt tgaacagaac
      841 caaattgatg ctgtttgggt gacggatatt acttacattc catgtaatga cggtcgcctc
      901 tatttgtcca cctatattga cttagcaact cgtattctac gttactatat ggtggattca
      961 cacatgaaaa aagagattgt cgtccgtcca ttacaaattt attaaggaga attgcctacg
     1021 gtaattcatt ccgatagagg tagccagcat cggtctttta tttatcaaga gctgttgacc
     1081 gaccaccaca tcacacattc aatgagccaa actgggactc ctgttgacaa tgcagtaatt
     1141 gaagcgtttc atcgatcaat caaatgagaa ttaatcgact ccaacaaata taaaagtaaa
     1201 atagagatga aggtgttaat ccaagattat ttagaagact actacccaaa caaaagaatc
     1261 catacaaaat ttatgatgac tccttgacaa tttgaagcga agaaaataa
//
LOCUS       DADVXB010000250         1279 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.257, whole genome shotgun sequence.
ACCESSION   DADVXB010000250 DADVXB010000000
VERSION     DADVXB010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.257"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(150..223)
                     /locus_tag="KB902_002775"
     tRNA            complement(150..223)
                     /locus_tag="KB902_002775"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(187..189),aa:Ile,seq:cat)
     gene            complement(413..>1279)
                     /locus_tag="KB902_002776"
     CDS             complement(413..>1279)
                     /locus_tag="KB902_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6809536.1"
                     /translation="HETANETATGRNEAQYMQRSWTSAYTAYIVGDGGNVYQVGQPGY
                     VQYGAGSYANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYTFIMDYNTGKELAR
                     VRADGIYRPDVNQGYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPKR"
BASE COUNT          367 a          261 c          235 g          416 t
ORIGIN      
        1 aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac
       61 tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaaattcta
      121 acacagaacg attcaaatgg ctacgttaat gtaccctgta ggactcgaac ctacgaccgg
      181 acggttatga gccgtctgct ctgaccaact gagctaaggg tactggttgt tgccacataa
      241 agccataaac aatcaaccag tagaatgtgt ggcaacaaac ctgttatcgc atagcttgga
      301 gtgtgactat ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaataa
      361 tttttatagt tgtcaatata gttatgtact gctcctcaac gaggagctat ttttatcgtt
      421 taggaatatt taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc
      481 cctctggatc attcgttgcc cgcatcatta catagacttt cttactagga aaattacgca
      541 tattgaaaga tacatgataa ccaacgtttc cagaagtatt ataaccttga tttacatctg
      601 gtctataaat tccatcagct cttactcgag ctaattcttt cccagtattg tagtccataa
      661 tgaaagtata ctcgtattta tagttagcaa tgtgccatcc agccacatgc aagtttgcgt
      721 tttcgatttc tccaaactga tcaatgtggg cgtaatttgt tccatctgtt agtgtaggat
      781 ttgcagcacc tgctcgagtt ggatcaatta ctggtttatc ctccgaagta gttggattat
      841 catccgtaaa accatgagcc aaatcatagg ctagtttttc tttacttaca cccatttcag
      901 aaagataacc gtaaggatct gtatgatcgc cccaaatatt ttgtgttacc cataaatgcg
      961 atttgattcc tggttggtta taaggagtgt ctaatgttaa tggaatacca tatttcattg
     1021 ctgaatctct agctaattca acgtatgcct tgtagttttt ctcaaacgtt gctttatcat
     1081 gtgtgtgttg taactcaatc tgcacgggac tgttggcatt agcatacgaa ccagccccat
     1141 actgcacata accaggttga ccgacttgat aaacatttcc gccgtctccc acaatgtaag
     1201 cagtgtaagc actagtccat gaacgttgca tatactgtgc ttcattgcgt cctgttgctg
     1261 tttcgttagc tgtttcatg
//
LOCUS       DADVXB010000251         1264 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.258, whole genome shotgun sequence.
ACCESSION   DADVXB010000251 DADVXB010000000
VERSION     DADVXB010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.258"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            82..>1264
                     /locus_tag="KB902_002777"
     CDS             82..>1264
                     /locus_tag="KB902_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBB6809537.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KI"
BASE COUNT          422 a          247 c          242 g          353 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atag
//
LOCUS       DADVXB010000252         1256 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.259, whole genome shotgun sequence.
ACCESSION   DADVXB010000252 DADVXB010000000
VERSION     DADVXB010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.259"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            489..875
                     /locus_tag="KB902_002778"
     CDS             489..875
                     /locus_tag="KB902_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6809538.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            973..1164
                     /locus_tag="KB902_002779"
     CDS             973..1164
                     /locus_tag="KB902_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809539.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
BASE COUNT          478 a          184 c          186 g          408 t
ORIGIN      
        1 ttcaaagaca ataattatta tgatccgtta ttatctaagc actatacaga taataggaat
       61 ttttcgtttc taaatactcc aatttgggaa tccaataaaa attttcgttc aaatacgtgt
      121 ctattcgaac tcttttctag ttgttaatta tgaaggggga agaaataaaa aatacaatct
      181 atacacgaat aagaatatta tccaaaagga ggttttagaa aagatttatt atacgtaaaa
      241 agctcaagac attttcttag ccataaggac atgtttgata tttaagaaga tatatgaatt
      301 ttcttttcta agtataaaga taactatcca ttatcaacta aaaaaacatt tttgaaaata
      361 aacatcagca gtcctatcaa tgcatgtgag cttatagaag ttattcgcag cgcagcataa
      421 ttgcattagc ttcttttcgt gttttttgcc tcttttccct ttaaatctta atggaggagg
      481 tgtgcaatat gtcagataac gacgaacgcg taaatgccca gttgattcga ttctttgaaa
      541 aggtcatttt gaacaccgct aatacttatt ataaaaaaca agaagaaatt caaaaacatg
      601 aacaacttga tcaactccca ccatatttgt ttactaaaga tactataaaa tttaaacaac
      661 cgattaatgt tttaaatgtg actctccttg ttgaagatat aaaattagca aaaatccttc
      721 ctttgttgaa agaacctgaa caaatttttc ttatcgaaaa atttatcttt aataaaactg
      781 ataaagaaat tggaaaggtt ctgggtatta caagacaggg tgcgacaaat ttaaaacatc
      841 gactttacaa aaaaattcaa aaaatgctgg tttaatatct gcataataac taattttgta
      901 tgcttctttg ctcgtcctcc tccttcccaa aaaaataaat agattataag ttcatgggaa
      961 gaaggtaaat ttatgaatac tttaaaagaa gatttcattt tagcaaagaa tggaaatgaa
     1021 gaagcagttg tggccattct caaaagattt agcgctttgg tccataagca atcctggaga
     1081 actggaaaat atgatcaaga ttgttatcaa gaatgtatgc ttgcaatata tctagctatc
     1141 tcgaaattcg aaattaaaga ataactcaac taagggagtc tgtgacataa gtaaaaagat
     1201 agtttcaaat ttcgaacaat aaatttgaag ccatcttctt tataattata aagtat
//
LOCUS       DADVXB010000253         1246 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.260, whole genome shotgun sequence.
ACCESSION   DADVXB010000253 DADVXB010000000
VERSION     DADVXB010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.260"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            200..742
                     /locus_tag="KB902_002780"
     CDS             200..742
                     /locus_tag="KB902_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809540.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="KB902_002781"
     CDS             898..>1246
                     /locus_tag="KB902_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBB6809541.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DADVXB010000254         1227 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.261, whole genome shotgun sequence.
ACCESSION   DADVXB010000254 DADVXB010000000
VERSION     DADVXB010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.261"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..541)
                     /locus_tag="KB902_002782"
     CDS             complement(<1..541)
                     /locus_tag="KB902_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBB6809542.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPI"
BASE COUNT          360 a          273 c          190 g          404 t
ORIGIN      
        1 aaatcgggtc tacaatacga tactgagtaa taaagtcatc cggcacatct acaatatcgc
       61 aggcaatatc cgcccgggaa aaatgcggat ctaaaaatag gtcatgaatg aatcctttca
      121 tggaactagc taaaaactgg cctatcttat tcggattaaa atcaatacga ccttttcctt
      181 catgaaattt aagtatttcg atatacgcaa tatcttctcc atattgatcg aataattgcc
      241 agccgtttat cccaactgat ttcaaatatc cctgattttc gttcaaacgc attaattgct
      301 cgaaatcgac aaaaacaact ccatttttcg tccaataagc tatggtatca ttcagttttc
      361 cgacaattgt aattcgatca atcgaccaat ttaattttag gggggtggtc gtaccttgca
      421 cacttaaccg cctgttagaa atacggttaa gtttttcgag ctgatttatc gttgttcttt
      481 tttctgcccc tcgaccttca atttttgatt gaatttcact caactgattt tcatttgcca
      541 ttttcgtcct ccaaacgaaa aaagagactt ttggaaagaa tttccagagt tcacgtaacc
      601 ctaaaaattc atatccaaaa atctctagct tgaagaaacc taaaaatatt cgtataatga
      661 acctgagtta cggagctagg tgaagtagtt tccgtaaata gtcgagagtg ttagcgcact
      721 gctcggcttt tattttgctc ttttttctcg ttttctttga ttatagcact cctcctaaaa
      781 aaataaaaag acctcaggga atttcattcc ccgaacccct tgagcctcct cctgccgaaa
      841 tggaaagggc gcacccgctg tttatttcat tcagctatcg gttttcacaa tctaacacga
      901 tcgttccgct accagtcgcc ttacaggctc cattttcgct cctctaacgt gttttaacga
      961 ttgtgccgat aactaaacga aataaacgct aaaaccgctc agaacgcaaa atatgccatt
     1021 ttagagctat tgtagaaaat gtagtttgaa atgcaatttt cttctttcag ctttttattt
     1081 cccacttgta aatctgctaa ttattttcta ccagacaaac cattgatttt ttggctatca
     1141 gttaactcac gattattatg agaaatgctt gtattctttg ttcccttttt gaacgaaata
     1201 ctaaacccta aggtgaaccc ctccttc
//
LOCUS       DADVXB010000255         1192 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.262, whole genome shotgun sequence.
ACCESSION   DADVXB010000255 DADVXB010000000
VERSION     DADVXB010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.262"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            63..764
                     /locus_tag="KB902_002783"
     CDS             63..764
                     /locus_tag="KB902_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6809543.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            936..>1192
                     /locus_tag="KB902_002784"
     CDS             936..>1192
                     /locus_tag="KB902_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6809544.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRL"
BASE COUNT          420 a          208 c          218 g          346 t
ORIGIN      
        1 tttacaaatt ctttaaaaaa agtgacaata aatatagtga acaataagga gaggactttt
       61 taatgcgtgt taataaaatc gattttcact tttcaaaact cagatatcaa cctgattttg
      121 aacatttctc ggatgaagag ttccaacaga tcaaggaaca tactgttctt cgttcttata
      181 aaaaaggaca gatccttttc gacgatggtg atcccagaca acggttgtat atcttgacca
      241 aaggactcgt tcgtttagaa cgttatgatg aaagtgcaac ttattactac tatgactatg
      301 tgaatacaaa taaccttttt cctatgtcag gaatgtttgg agaagagacc tacacttata
      361 cagctcaagc gatgactgat attgaaacat tctaccttcc tgtttcctac tatgaaaaat
      421 tagcacgaaa aaatcccgaa cagttgatct atatgataca aaaaatttct aaagtagttg
      481 aaatacatga attgcgtatc caaatcggat tgacctctag cgcctttgac cgggtaaaac
      541 aaaatttatt cattttgaaa gaagaattgg gcgtaccaac aaaagatggt catatcacca
      601 ttccttatcc gatcacctta aaagaattag cagtgaatag cggcacgaca cgtgaaactg
      661 ctggacaagt aatcaaacaa ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt
      721 ttactttctg taagacagct actactccag ctatgagaga ataacgcgaa caaaaataag
      781 cagtgaccct gataaatatg gctctataat ttatgggact gatgaatcag aattgattct
      841 tcagccccat ttttatttta ggtattaaaa aacatatcgt tctctagtat gattaaatca
      901 cgacaaaata aacaactgag aggacgatat gctatatgaa tgattctatc aaaaaaatgc
      961 tgcgattaat agagaaagat ttgatgatta cagaggtctc ttacgagacc tttcagaaga
     1021 aaaagacgtt gatcgtcgat gctgttttct cacctgctcc ccatacctgt agaaattgtg
     1081 gttctactgt ggtagatgga aacgggaaag taattgtagt gaaaaatggg aagaaggaaa
     1141 cgattgtccg ctttgaacaa tacaatcaca tgcctttggt tatgcgctta aa
//
LOCUS       DADVXB010000256         1170 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.263, whole genome shotgun sequence.
ACCESSION   DADVXB010000256 DADVXB010000000
VERSION     DADVXB010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.263"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(192..344)
                     /locus_tag="KB902_002785"
     CDS             complement(192..344)
                     /locus_tag="KB902_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809545.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(603..1019)
                     /locus_tag="KB902_002786"
     CDS             complement(603..1019)
                     /locus_tag="KB902_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6809546.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
BASE COUNT          351 a          259 c          163 g          397 t
ORIGIN      
        1 tttggggcat atataaagct acaaaaatct ttttggttag ttaaaactaa tttgaatcca
       61 aatcaaatgt gtgaaaaatt aaatacagta cttgataata acgattcctt attcatctgt
      121 gaactgcaaa aaaattatca aggtagagct acagaggaaa attggaaatt cattaacgaa
      181 catattttct cttagtaagg attagatatt ttttctctgt ttaaacaatt gcaaataccg
      241 tcaatatctg aattagaaac acttaccttt tgctccttgc tactaccaat agcttggagc
      301 aattcttgta tttcttctgg agtgccttct actgataatt tcatttttct tccctccaat
      361 acataaatta atagacagca acggatgata gataataaga acaatcagga ggagttgaaa
      421 ttcacatcct tattcttaat atttccgttg ctgcctatcg aagcttaatt taaaacgatg
      481 agggagattc cctcccttac attttatttt gtcgatcctg tttcctaatc tttcgacact
      541 atcataatat cacgttaaaa cactcaaaaa ccctacacta tccctacaaa aaccctacaa
      601 aatcaacgat actgaactaa cacgcctttt ttgtatgctt cagcaaattc gatcagcgcg
      661 atagatttca gcttctctac attcttctct ccgtatcctc gtatcaattg acctatttca
      721 taattagagt gcttatttac gtcacagaag ctatagtaga gtatctgacg actaatcaga
      781 ctaagagcca tcaaagccgc taaaatcgcg tctctctccg cttctatatc catcatctga
      841 atcaatgcat cctctgcctt attgccgtgc ttcggtgcct tcggcatatc cgtaataatc
      901 ggcgacttaa tatctatcaa agagcgacct gccatccgct ccaaacgccg aaagttcttc
      961 agcacatctc tcgcattaca tcttgtctgt ttgaaatcta cctctcgtaa caattgcatc
     1021 aagtcaaact gctcctttta tgtgatataa taaacttgtc tgttttatta tgttagtcgg
     1081 agcgatccgg cttttttatt tgtcattgat tagttccata tccaccaatc tcactactgc
     1141 taaattctct ttgcttttag ctgtccattt
//
LOCUS       DADVXB010000257         1112 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.264, whole genome shotgun sequence.
ACCESSION   DADVXB010000257 DADVXB010000000
VERSION     DADVXB010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.264"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(62..280)
                     /locus_tag="KB902_002787"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="KB902_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="KB902_002788"
     CDS             complement(546..740)
                     /locus_tag="KB902_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809547.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="KB902_002789"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="KB902_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          390 a          187 c          159 g          376 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta ta
//
LOCUS       DADVXB010000258         1085 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.265, whole genome shotgun sequence.
ACCESSION   DADVXB010000258 DADVXB010000000
VERSION     DADVXB010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.265"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(67..264)
                     /locus_tag="KB902_002790"
     CDS             complement(67..264)
                     /locus_tag="KB902_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6809548.1"
                     /translation="MILPDKYYQVIKWTVLTVLPATSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            complement(280..522)
                     /locus_tag="KB902_002791"
     CDS             complement(280..522)
                     /locus_tag="KB902_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBB6809549.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYESLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            complement(579..>1085)
                     /locus_tag="KB902_002792"
     CDS             complement(579..>1085)
                     /locus_tag="KB902_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809550.1"
                     /translation="TGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANETAI
                     KSTNSRVNEIENIITALTKEETYLLPASIVSGGSLKFTSRGGMTVATGSFKLAKDIAF
                     GEVLVNDLPDSMINIDNNAIGTGAVTGNSVSQIYVESNTRKVVANTAMKKDQWFTVGF
                     SYHSKLSI"
BASE COUNT          306 a          245 c          152 g          382 t
ORIGIN      
        1 aataaaaaaa gagccgttaa taggctcatc gcagtaatag taattttctt tttcatttgt
       61 ttcctcctat tttttcaaat tataagccga cacaccagtg ataacaccta aaaatgttgc
      121 tgctgcattg atagtcagaa ctgccatatc tgttccattc catccatatg ctttgcctag
      181 tgttgcaact aatacagatg tagccggaag taccgtaagt accgtccatt taatgacttg
      241 ataatactta tcgggtaaaa tcatttcttc tcacctcctt tacaatttag tcaagaaata
      301 gccaatgatc gtaatgccta aaccgatcat gtaaccccac gaccatttat tattggcttt
      361 catttctttg atatcttccg cattattaag cgcaatagaa tatgcctgat ccgctctatc
      421 ttttgcactt tccgcttttt cgcgtaatga ttcgtaatta tccaacttcg tttcaatacg
      481 cactaaacgt tctaccacgt cttgtattgc ttcatctttc aaccaactag cctcctttca
      541 ttgcaaaata aaaacgtact cgaatgagta cgctaaatct atatagataa tttactgtga
      601 tacgaaaatc caactgtaaa ccattgatct tttttcatag cggtattcgc aaccaccttt
      661 ctcgtattag attcaacata tatttgcgat acagaattac ctgtgacagc tccagtccct
      721 atagcattgt tatcaatatt aatcattgaa tctggcaaat cattaactaa aacttctccg
      781 aatgctatgt ccttagccaa cttaaatgat cctgtagcta ctgtcattcc accacgactt
      841 gtgaatttaa gagatccgcc acttactata ctagcaggta gcaaatatgt ttcttctttt
      901 gttagggccg taataatgtt ttctatctca ttaaccctac tattcgtact ctttatagca
      961 gtctcattag cgttcgcttt tgtttgagca tccttagctg tggtatctac ttcattaatt
     1021 gaagctgtca actgcgaatt aatctccgat actttcccat cggtataatt gtttgcttta
     1081 cctgt
//
LOCUS       DADVXB010000259         1016 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.266, whole genome shotgun sequence.
ACCESSION   DADVXB010000259 DADVXB010000000
VERSION     DADVXB010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.266"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(133..>1016)
                     /locus_tag="KB902_002793"
     CDS             complement(133..>1016)
                     /locus_tag="KB902_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBB6809551.1"
                     /translation="RERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIE
                     YTGNLSKTIEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGI
                     IPSVSGDTIRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVL
                     KVRDSGIVYYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLR
                     ESFKNEMHITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGV
                     SPKQYQLGLVDNFNNIS"
BASE COUNT          351 a          175 c          121 g          369 t
ORIGIN      
        1 attacttaga cgctcagatt ctacgaaaca actcaaatca gaaatttccc aaaaaatttt
       61 ttgttaaaat ccaatttcct caactcctcc aaactacgta aatgatatag tctcataata
      121 aaataaaacc tctcagctaa tgttgttgaa attatccact aaacctaatt gatattgctt
      181 aggagataca cctgcgtact ttttgaatac tctcgaaaag tgtgaagaat ctgaaaatcc
      241 taaacctaaa gaaacttcac tgatagtatg gtttgatttc aacattattt tagccgtaga
      301 aatttttcgc ttagagatat aattataaat cgtaatatgc atttcattct taaagctttc
      361 tcttaattta gtttcactta cagaaaaata attagctatt tcctttacag taattctttt
      421 atagatattt aagccgatga attgaacgac agaagaaatt aagggagaaa gatgctctat
      481 cttagttttt ccgatttcct tagtataata aacaatccca gaatccctca cttttaagac
      541 ctcaggtaac gatacagcta attcgttttc ttgtatcaaa gcatctctac tttgatacgc
      601 ttctattata tccattccta atgttataga cgtttgtgct aacttttcaa aaacaatgat
      661 agaataattt ttttcagacc gaatcgtatc tccactaaca cttggaatta ttccattact
      721 cagattaaaa accatgtttt ctaaatttcg aatatctcca tttttaacat attccagtat
      781 tttattttca taaagaaaca gatatatttc tggatcgtaa ttttgtgata acagattatc
      841 tattttgatt tgctcgatag ttttacttag atttcctgta tattcaatta acggttcatg
      901 gaatagatct tctatttttc cagtaaaaaa ataatgaact aaaatcagaa tatctcgaat
      961 gtctcctaaa gaatacaaag tcaaattttg caatgaatta tagagtcgtt ctctat
//
LOCUS       DADVXB010000260         1007 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.267, whole genome shotgun sequence.
ACCESSION   DADVXB010000260 DADVXB010000000
VERSION     DADVXB010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.267"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            373..1007
                     /locus_tag="KB902_002794"
                     /pseudo
     CDS             373..1007
                     /locus_tag="KB902_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          182 c          185 g          297 t
ORIGIN      
        1 agtgtttcaa agttagtaga gaaaatgtag ttatatattt aaatttttac cagaaagaaa
       61 tgaacacctt caattatcta aatctcgaaa atggttagat gtaatcatca ggaaaaacaa
      121 tcttaaacga attactattc atggtcttag acacacacat gctagcttgc ttttagcaag
      181 ctagtgcaaa tattaaagat gtgcaagagc gtttaggcca ctcttctatt caaatcatta
      241 tggatctata tattcatatt acagacaaaa gaaaagaaga aaccgtagcg caattcgcaa
      301 aatataggct ctataattta tgggactgat gaatcaaaat tgattcttca gtcccattgt
      361 tattttaggt atatgattcg tacattgaaa gagttgaaaa actatcttcc gaagccgtca
      421 aaaaggaccc tgccaaaagt attgatggtg gatgaatttc gttcgcacgc ttcaattgtg
      481 gataaaatga gctttatttg tgcggatggc gagactggaa aactcattga tattttgcct
      541 acacgaaaat tgtctcgatt aacacactat tttagtcgct gtgcaaatcc tgaagcggtg
      601 gaatatttag tgacagatat gaacgccgcc tacttccaac tgacaaaacg tgtcttacca
      661 aatgcgaaag tcgtcattga ttgttttcat atcatcaaac atttgaatca ggcgttcaat
      721 gattttcgtg tacaagaaat gaaaagatta caccagttag ggcaacgacg ggaagccgag
      781 aaagtgaaaa agaactggcg ctttcttcta aaaaaccgtc aaaaaatcaa tcactatgat
      841 tacaaaacat ggcgcagttt tcgtgcacct aaatacccgc tactcactga agcaatgatg
      901 attgatcgat tgctggcatt ttcaacgcct ttaaaggacg cctatacttt tttccatgag
      961 ctgaccgaag cctttagaga caaggaatca gacttatttt ttacctt
//
LOCUS       DADVXB010000261          996 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.268, whole genome shotgun sequence.
ACCESSION   DADVXB010000261 DADVXB010000000
VERSION     DADVXB010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.268"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            100..840
                     /locus_tag="KB902_002795"
     CDS             100..840
                     /locus_tag="KB902_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809552.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT          363 a          179 c          195 g          259 t
ORIGIN      
        1 tcatcgctat tttcttaaaa taatcagcgc attgctactg aaaacaatga atctgtgcta
       61 ttattgagaa aagttccatt tttgagaagg atggtttgaa tgaaagaaat cagacgaaaa
      121 catttccgtt ttcctgcgta cgatgatgag ttaggcgtaa aattaaccaa cgacaagaag
      181 cgagtattat ttgacggaca agaagatctt ttgactgaac agaatcagtc cccgtttgaa
      241 cagatgaaag aatttcattt cacgaacacg aacaccgaga aaatccgtcg caagcgtcgt
      301 gcaacaaatg gattgaagtc agctccgcgt aaggaaaatt tggaaaagca taaaggaaaa
      361 ttaccggatt ataccggcca ttaccaatca gaaatcacat cgacaggacg aaaaaaactt
      421 tttggtgatt cctctcgttc tgtcagacaa agtgaaacaa ggacagagtc caagcatact
      481 acacgaaacg catctgttga cacgaaggtg cgggagcgtt cttattttgt tcctaaatat
      541 gtacccgcat cgattatccc agaccctaga gaaagcaaaa tttctgagga tcatttaatc
      601 gaatcgatga aaaaaacgga tgactcttat ctgttgttcg atacagaacc gacgccgtat
      661 caagaaaaaa gaaatggtga gccgtctgta cgaacattca atcgaacaaa aacgttagag
      721 gaaacaaagc agtcagaaga aaaaaaatcg aaaaaaagcc atggtatctt agaacgctca
      781 ttacaaggat tgatcgatga tcaaggaaac tctttgggag aaaatagcta ttttaaataa
      841 gtgatataca aatttatatt cggctacagt tggaaaggaa acgctgcggc gtttccttat
      901 tttatactct atccgaaagt ttatatcgta tcctcaaatt tttttgagtt taagcgaatt
      961 ttttctccca ataagtaaga aaataatggc aaaata
//
LOCUS       DADVXB010000262          990 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.269, whole genome shotgun sequence.
ACCESSION   DADVXB010000262 DADVXB010000000
VERSION     DADVXB010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.269"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            17..427
                     /gene="spx"
                     /locus_tag="KB902_002796"
     CDS             17..427
                     /gene="spx"
                     /locus_tag="KB902_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6809553.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            441..797
                     /locus_tag="KB902_002797"
     CDS             441..797
                     /locus_tag="KB902_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBB6809554.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          340 a          155 c          195 g          300 t
ORIGIN      
        1 aaaaaggagt gagaaaatga taaaagtata tacttcgcct agctgtactt cctgtagaaa
       61 agcaagagca tggttgcaag cgaatcaact tgaatttgaa gagaagaata tttttgccga
      121 accgttaaca gaaagtgaga tcaaaaagat cttggcagcg actgaaggag gagttcaaga
      181 tattatttcc actcggtcga aaatttacga aaagctgggc atagatttta acgaattaac
      241 tttaaagcaa atgatcgtct tattcaaaga atatccttca ttattgagac gacctatttt
      301 gattgatgaa aaaagaatac taatcggatt taatgaagat gagatccggt catttgtccc
      361 tcgtgaaatt cgatgtgttg ccagaaatct gatctattta caaaacaata acatcttaaa
      421 ttcataggga gggagccttc gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa
      481 gtctgaaggc gaaacaatgg ttagaacacc atcaattgcc ttatcaattt gttgacttag
      541 aagaacgcga tctaagtaca gaagaagcag aagaattatg cagttttgaa gaagtgcaag
      601 cagaacagct atttgcgact tggtctgagg cttttcacaa cattgcgatt gacctttcct
      661 gtgtaggaaa aaaacaactg atttttttat gcacacaaca taccaatctc ctcagacgtc
      721 ctttgattat tatcgatgaa gttctattta ttggatacaa tgagcagttg atggaacagc
      781 ttatcttaaa taaatagact ttaactgttt taatcaagtc actgagcatt tcatacagtt
      841 gtaacagtcg aacacttagc atcaagcgtg ttatgtgttc tttttttgac tttatttttc
      901 tactatagag acatgctcaa tttatgtggt caaaattcaa atctaggtgg ggatatagag
      961 ttaaaaatat attgacatgt gtaaatttac
//
LOCUS       DADVXB010000263          968 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.270, whole genome shotgun sequence.
ACCESSION   DADVXB010000263 DADVXB010000000
VERSION     DADVXB010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.270"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(317..523)
                     /locus_tag="KB902_002798"
     CDS             complement(317..523)
                     /locus_tag="KB902_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809555.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
BASE COUNT          282 a          203 c          160 g          323 t
ORIGIN      
        1 tttcctttcg tttatatgta tcgctcttta ttggtcttct atactcatat actttttcgc
       61 cattaccttt atgaacagtg attacttcat acttctgttc taagtattgt ggtctataca
      121 ttgttgtttc ctcctttgtg caaaaataaa aagaccactc aaagagtgat ctaatatgta
      181 atagtaactt gcacgatgca caaaacgcgt acgaaattgc gcacccctat atttttaaac
      241 cgccgatgcc tcggttgctt aaagtcgctg gagtgggatt gcaccactca cgagaactta
      301 ccaggctctc acgaggctac tcgccattta ccgctgcgtc ttctacttcc gccacagtga
      361 ccgaagcttg gtggtgtaca gatagcacac ttactacatt gccgtacgta gcaccgtata
      421 gcttcttaac gatctttttt cggtagtcgt aaccgtcata ggcatttaat gtcgctggca
      481 aggaatcgaa ccttgcatgg ttgccgaagc attgacctag cacacatgct tagcgtctac
      541 cctttccgcc acagtgacac tataaaatta ttcttggctg ctactatttt ttattttgcc
      601 catttttaaa tccaatcata tagacattaa gacagagcgc aaaaattgaa attattaatg
      661 gaatcatttc tcttcaccca cctttagtta tcgtgtgaat aattaaaaaa caatagacag
      721 caacaaaata acattgcttt gataatttgg tataaaccac tataaatttc ttttcttgca
      781 attattttca atatatgcta gattatcaac cgatatagtc actgcctgta ctagcggaaa
      841 ctagtgcagg ttttttgttc tatttactca aaagttatta cgataaatta atattgtgaa
      901 aataaatact aggcgtataa ttttatttat cagcgagtgg tccgctgaaa tataaaacaa
      961 ggatgtgc
//
LOCUS       DADVXB010000264          895 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.271, whole genome shotgun sequence.
ACCESSION   DADVXB010000264 DADVXB010000000
VERSION     DADVXB010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.271"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..208)
                     /locus_tag="KB902_002799"
     CDS             complement(<1..208)
                     /locus_tag="KB902_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809556.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQT"
BASE COUNT          275 a          154 c          128 g          338 t
ORIGIN      
        1 aagtttgaat atccacaaat ttttctaaca accgatcaaa ttggtctttt ttataattca
       61 gaagagcgtg atcaaaatca ttttcgatca aaacttttag gtattgattt cgactccatt
      121 ttttgccagt cttgaccgta agttcttcac aacgtttgtc aattttatta atgtactttt
      181 cttcaatatt tctaattaat aagtccatat tttcctccaa atttattatg tgtagggata
      241 tgtgtagcta cacatatccc tacacatttt ttgattttgc tacacacaaa cgcttatttt
      301 actgcccaca ttcgctttca tcctacccac aaatctacac acaaatccaa aattttgata
      361 tcatttatct ttcttagaaa cgtggtaggc acagcctacc tagcaccttt cgtaagaaag
      421 tgatatcacg tttccttatg ctctttaaaa attaaggtta tttgtgtatt tagacaataa
      481 aaaatccttc taactttgtc gattagaagg aaatattttg tcatatgaaa aatgaattta
      541 agaaaaagtg tatgctataa ttgatacgct gtcttcctgt ttggttgaaa tcttcagcca
      601 gaaaggagga gtgttaaatg ttttatgtgc ttgatgtttg cgttagaatc gtggttaatg
      661 ttttctccca tctcattaac aaatggttag attctaaaca tgataaagac agctagcctg
      721 ttcattattt ggttaatagt gaataaagaa aagagcctta cgcagctgca actgctaggg
      781 ctctttttga gtattaaatg ttttatgtgt ttgcattatc agtatagcat acactttttt
      841 cacagacaac tttctacatt ttttcttctt ttttcaatca aaataaacta atgaa
//
LOCUS       DADVXB010000265          893 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.272, whole genome shotgun sequence.
ACCESSION   DADVXB010000265 DADVXB010000000
VERSION     DADVXB010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.272"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(80..152)
                     /locus_tag="KB902_002800"
     tRNA            complement(80..152)
                     /locus_tag="KB902_002800"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(117..119),aa:His,seq:gtg)
     gene            complement(155..228)
                     /locus_tag="KB902_002801"
     tRNA            complement(155..228)
                     /locus_tag="KB902_002801"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(194..196),aa:Trp,seq:cca)
     gene            complement(235..315)
                     /locus_tag="KB902_002802"
     tRNA            complement(235..315)
                     /locus_tag="KB902_002802"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(279..281),aa:Tyr,seq:gta)
     gene            complement(317..392)
                     /locus_tag="KB902_002803"
     tRNA            complement(317..392)
                     /locus_tag="KB902_002803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(357..359),aa:Phe,seq:gaa)
     gene            complement(428..500)
                     /locus_tag="KB902_002804"
     tRNA            complement(428..500)
                     /locus_tag="KB902_002804"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(465..467),aa:Asp,seq:gtc)
     gene            complement(510..582)
                     /locus_tag="KB902_002805"
     tRNA            complement(510..582)
                     /locus_tag="KB902_002805"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(547..549),aa:Val,seq:tac)
     gene            complement(598..669)
                     /locus_tag="KB902_002806"
     tRNA            complement(598..669)
                     /locus_tag="KB902_002806"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(634..636),aa:Glu,seq:ttc)
     gene            complement(684..773)
                     /locus_tag="KB902_002807"
     tRNA            complement(684..773)
                     /locus_tag="KB902_002807"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(737..739),aa:Ser,seq:gga)
     gene            complement(813..886)
                     /locus_tag="KB902_002808"
     tRNA            complement(813..886)
                     /locus_tag="KB902_002808"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(850..852),aa:Asn,seq:gtt)
BASE COUNT          249 a          244 c          206 g          194 t
ORIGIN      
        1 ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct
       61 ataccccaag aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca
      121 atccggtgcg ttaaccactt cgccacattc gccatggcag gggcagcagg aattgaaccc
      181 acactaacgg ttttggagac cgctgttcta cctttaaact atgcccctat aaaatggagg
      241 agagtggatt cgaaccactg aaccctaagg aacggattta cagtccgtcg cgtttagcca
      301 cttcgctact cctccatggt ggcgcgggac agaatcgaac tgccgacaca cggagcttca
      361 atccgttgct ctaccaactg agctaccgcg ccatatttta aaattattaa ttgaataaca
      421 agaacgacgg ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcatgtt
      481 aacccctaca ccacggaacc agttcattat ggaggttaac gggatcgaac cgctgaccct
      541 ctgcttgtaa ggcagatgct ctcccagctg agctaaacct ccaacattca attaaaatga
      601 cccgtacggg attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac
      661 caacgggcca ggtaaatttg ctacggagag taagggattc gaacccttga gacagtttgg
      721 caccatctac atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga
      781 aagaagctca atactctttc tcaaaatgag aactccggca gtaggactcg aacctacgac
      841 atcatgatta acagtcatgc gctactacca actgagctat gccggaataa cat
//
LOCUS       DADVXB010000266          892 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.273, whole genome shotgun sequence.
ACCESSION   DADVXB010000266 DADVXB010000000
VERSION     DADVXB010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.273"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..890
                     /locus_tag="KB902_002809"
     CDS             <1..890
                     /locus_tag="KB902_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBB6809557.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          246 t
ORIGIN      
        1 ttagaaacct tgattcaaga acaagatttg agcaagaaga aatcaaggtt aaaacaatcc
       61 ttcagctcaa aaaagaattt aaattgaatc tattactttc aattgcacaa ttagcgaagt
      121 caacttatta ttactgggta aaaaaattag ataagccaga taaatatagc aagataaagc
      181 aagaaattac agcgattgta aaagaatcaa gaaactctta tggttatcgt agagtcactt
      241 tagcgttaaa gatgaaagga tatacaatca atcataaaac agttagaaaa ttaatgtccc
      301 aaatgggact tacctgtcaa atccgaataa agcgatataa atcttataaa ggaacagtag
      361 gaaaaattgc caagaatgtg ttaaaacgaa atttttcagt agatacaccc aataaaaaat
      421 gggtgacaga cgtcactgaa ttcaagataa aaggaagaaa aatctatcta tctcctatac
      481 ttgatttatt taacggagaa ataattagtt atagtatatc aactagtcca acatataaac
      541 tgattgaaga aatgcttcaa caagcaatta aaaaaaaggg aactgagggt tcactgattc
      601 tacattcaga tcaaggatgg cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga
      661 ataacattat tcaaagcatg tctagaaaag gaaattgctt agataattct gtaatagaaa
      721 atttttttgg tgtgcttaaa tcagagtttt tttatcgaga aaaattccga tcaattgaga
      781 tatttcaaag taaattaaat gagtatatta ggtggtataa taacaaaagg ataaaactaa
      841 agttaaatgg actatctcca gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DADVXB010000267          880 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.274, whole genome shotgun sequence.
ACCESSION   DADVXB010000267 DADVXB010000000
VERSION     DADVXB010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.274"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="KB902_002810"
     CDS             complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="KB902_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6809558.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          251 a          186 c          135 g          308 t
ORIGIN      
        1 gtacacggtg ttccaaaagt agcttcttcg gaaataagtt ggaatttcac aaaaattcaa
       61 gaagtaattt tcgtaaattc cttcttattt cttgaagctg attacttctg tcacaacctc
      121 tttttattat tgagaatttg gtcgaggaat aatcgttttt gccatccaaa tatccggttt
      181 gtcccagcca tttgcatttg gtaagacacc tacgatttta taacctaatt tttcatagaa
      241 ttcatacgga tgttcacgaa ggttctggat ggaagccact ttatcaaatg tatgctcata
      301 caggtccgtt tgacttaacg ttgttccatg gtctaaatca tccgtaccta aataaatcgt
      361 gattcctcct ctggaagcta cttctttttc taagtaattg actaatcgag tacctatttg
      421 gttctttcgt cgggagcttt ctacaactaa tggatgcaat tcccaacctg tgataccgta
      481 ttgagggatt gcaccaataa atcctactaa ctcatcttgg tctaccgctg ctaccgcgat
      541 tcgttctgga ttcatcattt cttctacttc ttctgccgag ctgtctccat attcttccgg
      601 ccaagtcagt ctcagtaaat cagaaagctg atctttcaat actggattat tacggtcaaa
      661 ttcactgatt atcatacgtc ttcccccttg ttcttgctta ttctaacagt ccttttgaaa
      721 aaacgaaatg ttctcgctca aaaatcttta gctaccaatc agtatctcta ttctttcatt
      781 atttatctta cttataaaat aaaaaaatta tacagaaaca ctttattcaa aataggaaag
      841 atcaggaaag ccatcaattg gaggaaaaaa ctctgtttgt
//
LOCUS       DADVXB010000268          866 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.275, whole genome shotgun sequence.
ACCESSION   DADVXB010000268 DADVXB010000000
VERSION     DADVXB010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.275"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>866
                     /locus_tag="KB902_002811"
     CDS             <1..>866
                     /locus_tag="KB902_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6809559.1"
                     /translation="NRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQEYDK
                     LILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYIGVEI
                     AEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGRKK
                     IEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKDIYAI
                     GDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFNYNFY
                     AAGLNLKTARLL"
BASE COUNT          336 a          109 c          148 g          273 t
ORIGIN      
        1 aaatagaaga gaactaaatt ctaagataaa aaagttgttt ttggagacag cagttgacaa
       61 aattgatatt caaaataaaa agattatttg tgtaaaaaaa gatggcacaa gattttccca
      121 agaatatgac aaacttatac tagctacagg ttcaaagcaa attatgttag atgtaccggg
      181 gaataattta gctaatattt tttcgataaa gaattttcca aatgctaaag agatttttaa
      241 agctttagat gataatacta ttaaaaaagt aggaattatt ggagcaggat atattggagt
      301 tgaaattgct gaagccataa gaaaaagagg gaaagaagta tatcttttcg atgttgcaga
      361 tagagtgttg tcgacttatt acgaccgtag tttttcagat aaagttgaag aaatactatc
      421 aaaaaatgga atacatcttt gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa
      481 gattgaaaaa atagtcacta caagtggtac ccaatactct atggatatgg tcgtacaagc
      541 tataggattt ctatctaata gtccaattgg caaaaaggaa ctcttgagag atgttagtgg
      601 agcatatcta actaatgaat accagcaaac aaatataaaa gatatatatg ctattgggga
      661 ttgtgctaca acttttttta cgtccattaa tagaagtagt gttgattttt ctatttctaa
      721 tgctctaaga acagcttata ttgcaactca acatattgac aatcaagatt ttacaccttc
      781 tggttcccaa tttacaaatg gcttttctat atttaattac aatttttacg cagcaggttt
      841 gaatttaaaa acagcacgat tattaa
//
LOCUS       DADVXB010000269          864 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.276, whole genome shotgun sequence.
ACCESSION   DADVXB010000269 DADVXB010000000
VERSION     DADVXB010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.276"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>864
                     /gene="bsh"
                     /locus_tag="KB902_002812"
     CDS             <1..>864
                     /gene="bsh"
                     /locus_tag="KB902_002812"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6809560.1"
                     /translation="TSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVNDLDTHYAMI
                     GIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFIPWILGQCS
                     TVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHIYDNPVGVL
                     TNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDLSSVSRFVK
                     ATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSCCNVDKGIY
                     YYRTYEDSQIT"
BASE COUNT          296 a          118 c          157 g          293 t
ORIGIN      
        1 taacaagtga tcattatttt ggaaggaatt ttgattatga aatatcttac aatgaagtag
       61 tcactattac tccaagaaat tataagttga attttcgaaa ggtaaatgat ttggatactc
      121 attatgcaat gattggtatt gccgctggta tagctgacta ccctctttat tacgatgcga
      181 caaatgaaaa aggattgagt atggctggac taaatttttc tgggtatgct gattataaag
      241 aaatacaaga agggaaagac aatgtatctc cttttgaatt tattccttgg attttaggac
      301 aatgctcaac agtaggagaa gctaaaaaat tgttaaaaaa tatcaattta gcaaatataa
      361 attatagtga cgaacttcct ttatcccctt tacattggct attagctgat aaagaaaaat
      421 caattgtcat tgaaagtatg aaagatggac ttcatatata tgataaccct gtgggcgttc
      481 ttaccaataa tccttcattt gactatcaat tatttaattt aaacaattat cgtgtcttat
      541 cgagtgaaac tcctaaaaat aatttttcaa atcaaataag tttgaatgcc tatagccgcg
      601 gtatgggagg gataggcttg cctggagatt tatcctcagt atctcgtttt gttaaagcga
      661 cttttacgaa gctgaattct gtatctggag attcagagtc agaaagtatt agtcaatttt
      721 tccatatctt aggttcagta gaacaacaaa aaggtttgtg tgatgttggt gatggaaaat
      781 atgaatatac aatttattct tcttgttgca atgttgacaa aggaatctat tattatcgaa
      841 catatgaaga cagtcaaatt actg
//
LOCUS       DADVXB010000270          861 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.277, whole genome shotgun sequence.
ACCESSION   DADVXB010000270 DADVXB010000000
VERSION     DADVXB010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.277"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..861)
                     /locus_tag="KB902_002813"
     CDS             complement(<1..861)
                     /locus_tag="KB902_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809561.1"
                     /translation="MLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANLYAE
                     FAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFSIDQ
                     EITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCLQKI
                     QLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLLEQL
                     AQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGFHSI
                     HHFSSAFKKYT"
BASE COUNT          292 a           97 c          155 g          317 t
ORIGIN      
        1 tgtatatttt ttaaaagctg aagaaaaatg atggatcgaa tgaaatccta atatatctgc
       61 aatttctgta taggttaatt cattttctag cacgagacgt tttgcttttt ccatttttag
      121 ttctttaaaa tagctaataa cactttttcc attcactttt ctaaaatgtt tttttaagct
      181 ggctggactg ataaaaaaaa tttgggctaa ttgttcaagc aaaaaatttt ctgaaagatg
      241 ttcttctaaa tatcgtatga ttggatcaac taattcatct gaataaagaa tatgcttttt
      301 tttaggaatg actttctcat ttgaaggtat tgtcaataaa gcaagttcct gttgataatg
      361 ccttggtaag gaagacaatt gaattttttg cagacaataa gtaactaata aggaaagcaa
      421 atgaatgctc atctgttggc atagtatgaa aaaagaattg atttcctgat cataggaaat
      481 agctggctta ctatgtttta gataatcaat tttgaactgt tcatttttca gaaaagtaat
      541 gatagatgtt atttcttgat ctatagaaaa agattgtccc gtaatatgtg ctaataattg
      601 ctcatcaaaa taaaactgga taatgataaa agtttgtgtt tccttttgag tagaaaagat
      661 ttggacttct tgctgtttat caatgaataa aagggaagga ttatctagtt ctatagattt
      721 atgtgcaaat tcagcatata aattagcgct ttcatttatt agtagtcgaa aatagggagc
      781 agcagataaa tgaagatggg tatctatgga ataggttagt gtttttttga caagattgga
      841 ggattggttg tttgttaaca a
//
LOCUS       DADVXB010000271          847 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.278, whole genome shotgun sequence.
ACCESSION   DADVXB010000271 DADVXB010000000
VERSION     DADVXB010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.278"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            69..644
                     /locus_tag="KB902_002814"
     CDS             69..644
                     /locus_tag="KB902_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6809562.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(713..>847)
                     /locus_tag="KB902_002815"
     CDS             complement(713..>847)
                     /locus_tag="KB902_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6809563.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT          236 a          144 c          181 g          286 t
ORIGIN      
        1 cgttctttta aatgcacaag aagaaacgat tatgaaagat ttggaaaggt taaagatggg
       61 ctaacaaaat gaataaaaac aaaatggcaa ctcgcgtact tacagtgatg gctttgtgta
      121 ttgggatcaa ttatattgga ggaacgattg ctttatggct tcgtttgcca atctatctcg
      181 attctatcgg aacgattttt gctggtgcat tgcttgggcc tgtacctgga atgctgacag
      241 gattgtccag cggtatttta agtggagtga ctacagatat tttttctctg tattattcgc
      301 caatccaaat tctcacaggc ttgcttgctg gattgatttt gccaagatat ctcggcaaag
      361 ataaaaacag cttgaaactg ttattactcg ctttgatttt gtcggtacct ggaacgatcg
      421 tttcttcgat cattaccgtt cagttatttg gcgggatcac ctcctcagga tccagtatga
      481 tcgttcagct attacatggg ttaggtttaa gtcagacaac aagtgtgatc ttggtacagg
      541 cgggtacaga ctaccttgat cgcttgttgt ctatcgtcgt tgtttcatta gtcatcacta
      601 tgttgcccca acgcttgata tattcaaaaa gaaaaatagg ctgaataaac agagctggat
      661 tagcaaaata atgctaatct ggctctgttt tttcatttta ttatttgtca aattaagcga
      721 gacaaaactt tccatttacg taactcaaaa aaacttctaa tggtgtttgg taatttagtg
      781 attttctagg gatatggttt cttttggacg caacggatga gatgaatcct tgattgactt
      841 ggttgaa
//
LOCUS       DADVXB010000272          811 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.279, whole genome shotgun sequence.
ACCESSION   DADVXB010000272 DADVXB010000000
VERSION     DADVXB010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.279"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>811
                     /locus_tag="KB902_002816"
     rRNA            <1..>811
                     /locus_tag="KB902_002816"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          205 a          181 c          247 g          178 t
ORIGIN      
        1 atcgtaaaac tctgttgtta gagaagaaca aggatgagag taactgttca tcccttgacg
       61 gtatctaacc agaaagccac ggctaactac gtgccagcag ccgcggtaat acgtaggtgg
      121 caagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggtttctt aagtctgatg
      181 tgaaagcccc cggctcaacc ggggagggtc attggaaact gggagacttg agtgcagaag
      241 aggagagtgg aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccagtg
      301 gcgaaggcgg ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca
      361 ggattagata ccctggtagt ccacgccgta aacgatgagt gctaagtgtt ggagggtttc
      421 cgcccttcag tgctgcagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg
      481 ttgaaactca aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg
      541 aagcaacgcg aagaacctta ccaggtcttg acatcctttg accactctag agatagagct
      601 tccccttcgg gggcaaagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat
      661 gttgggttaa gtcccgcaac gagcgcaacc cttattgtta gttgccatca ttcagttggg
      721 cactctagca agactgccgg tgacaaaccg gaggaaggtg gggatgacgt caaatcatca
      781 tgccccttat gacctgggct acacacgtgc t
//
LOCUS       DADVXB010000273          803 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.280, whole genome shotgun sequence.
ACCESSION   DADVXB010000273 DADVXB010000000
VERSION     DADVXB010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.280"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>803
                     /locus_tag="KB902_002817"
     CDS             <1..>803
                     /locus_tag="KB902_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBB6809564.1"
                     /translation="IVHNQVYFGGGINLWLAKKNGIRQRIAHSHATEDGKSQNIVMNV
                     LRKFLTKLLLQNATDYLAVSQEAGESLFQNHPFEIVHNGIDLELYSKNSEAKVNKRKE
                     LDISMSTFVVGNIGRLEKQKNQSYLLEIFLEILKMNSDSYLILVGEGSLRNKLKAKAV
                     ELDIEKRVKFLGERNDIPELLSVMDVFVMPSLYEGLPMVGLEAQAAKLKLVLADTISK
                     DTKLTNNVDFVSLDETPQEWAKKVIKEPYANKITQELKSYDVSYTTEQM"
BASE COUNT          309 a           98 c          156 g          240 t
ORIGIN      
        1 tatagttcac aatcaggttt attttggcgg gggaattaat ttatggttag ccaaaaagaa
       61 tggaatcaga cagagaattg ctcatagcca tgcaactgaa gatggaaaat ctcaaaatat
      121 tgtaatgaat gtattgcgta aatttttaac caaattgttg ttacaaaatg caacagacta
      181 ccttgccgtt agtcaagaag ctggtgaaag tctgtttcaa aaccatccct ttgagatagt
      241 tcataatggt attgatttag agctttatag taaaaattca gaagctaagg ttaataagag
      301 aaaagaattg gatatctcaa tgagtacttt tgttgtggga aacattggac gattagagaa
      361 acaaaaaaat caatcttatt tgttagagat ttttttagaa atactaaaaa tgaattctga
      421 ttcttacttg attttagtag gtgaagggtc acttagaaat aaactgaaag ccaaagcagt
      481 agaattggat atagagaaaa gagtaaaatt tttaggagaa agaaacgata ttcccgagtt
      541 attatctgtg atggatgttt ttgtaatgcc ttctctttat gaaggtctgc caatggttgg
      601 attagaagca caagcagcaa aattaaaatt agtcttagca gatactattt ccaaagatac
      661 aaagttaaca aataatgtgg attttgtatc attagatgaa acaccacaag aatgggcaaa
      721 aaaagtaata aaagagccgt atgctaataa aataacacaa gaactaaaga gttatgatgt
      781 ttcgtacact actgaacaaa tgg
//
LOCUS       DADVXB010000274          770 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.283, whole genome shotgun sequence.
ACCESSION   DADVXB010000274 DADVXB010000000
VERSION     DADVXB010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.283"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(109..>770)
                     /locus_tag="KB902_002818"
     CDS             complement(109..>770)
                     /locus_tag="KB902_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HBB6809565.1"
                     /translation="RIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQ
                     PLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLT
                     DVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQY
                     QFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEA
                     A"
BASE COUNT          213 a          177 c          148 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcggc
//
LOCUS       DADVXB010000275          769 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.284, whole genome shotgun sequence.
ACCESSION   DADVXB010000275 DADVXB010000000
VERSION     DADVXB010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.284"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(36..>769)
                     /locus_tag="KB902_002819"
     CDS             complement(36..>769)
                     /locus_tag="KB902_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBB6809566.1"
                     /translation="ICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
BASE COUNT          294 a          135 c           93 g          247 t
ORIGIN      
        1 gtaaaggagt ccaagcaatg aaagctgtct tcatattaat tctccttttt taaatacaag
       61 taagaaatgc ttcccaaata ataccagaaa acaattgaaa tgacatcgcg cttattgaaa
      121 agtacatgag cctccaccat ttcatctata aaaatagata gtataaaaat taaaacaata
      181 ccaagaaacg cataattcac tttacttcta aaaaatgttt tgagtaaact aaagatattt
      241 aacacataga aagcatagat acatataaaa gcaattatac cacttgatac aagtacttga
      301 agaaatccat tatgcatgtt tccatgtgct ctttttagtt cattcacatc tgtagtatca
      361 agatctactt ttttcaaaaa ttttgcatcg ctattcccat agaaatcggt ctctccataa
      421 ccaaataaca aagttggtct tataacttta agcgcagctt tccaaatcgt aaaacgacca
      481 gctgaaattt cggagttatc actagaatgc tgtaatatta cttctttttc tggaagtgga
      541 gttttatctg attcatttga ctctataact tctacttttc tatcaatcga tacaggaatt
      601 gttgctaaaa aatccttagc ataattagta ccaaaagaaa aatataccaa tagaactaat
      661 aatatgctta ccatccattt gatttttaca ggtagtactt ctctaatgct ctttctaaat
      721 tttgaattgg caaacaacaa aagaaataat actaaaaaag aacaaatta
//
LOCUS       DADVXB010000276          764 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.285, whole genome shotgun sequence.
ACCESSION   DADVXB010000276 DADVXB010000000
VERSION     DADVXB010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.285"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..328)
                     /locus_tag="KB902_002820"
     CDS             complement(<1..328)
                     /locus_tag="KB902_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809567.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLE"
     gene            complement(400..>764)
                     /locus_tag="KB902_002821"
     CDS             complement(400..>764)
                     /locus_tag="KB902_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6809568.1"
                     /translation="TLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNT
                     GKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTK
                     GGAQDFHDKRWYLNIPQR"
BASE COUNT          216 a          152 c          119 g          277 t
ORIGIN      
        1 tctcaagtga agaagcaccg ccttcttcat attgctctat ccatttactt agagttctat
       61 ttgaaccgat attaaatttt ttagcagttt cttggataga aagaccattt gtttccatat
      121 attctataac atcaagttta aattttgtag tgtagctttt gccacctcca accaagcctt
      181 cccaaccatg atagttataa atccttaccc aatgtctaac cagtgtacga tttatttgat
      241 atttatgtgc aagatatttg tagccgcctt cgttatttaa atagtctgaa actacttttt
      301 tcttaaaaac aaatgtatat ttccgcaaaa aaagcacccc ttttaattag atttctagtc
      361 taacttttgg ggtgcacatc acaaagaggg ggggattttt tatcgttgtg gaatatttaa
      421 ataccaacgc ttgtcatgaa aatcttgtgc tccaccctta gtatttcctt ctggatcgtt
      481 tgtcgcacgc atcatgacgt atactttctt attagggaaa tcacgcatat tgaaagatac
      541 atgatagcca acatttccta aagtattata agcttgattt acgtctggtc tataaatccc
      601 atcagctctt actctagcta gttcttttcc agtattgtag tccataatga aaatatactc
      661 gtatttataa ttagcaatgt gccatccagc tacatgcaag tttgcgtttt cgatttctcc
      721 gaactgatca atgtgggcgt aatttgttcc atctgtcagc gtag
//
LOCUS       DADVXB010000277          753 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.286, whole genome shotgun sequence.
ACCESSION   DADVXB010000277 DADVXB010000000
VERSION     DADVXB010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.286"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            68..304
                     /locus_tag="KB902_002822"
     CDS             68..304
                     /locus_tag="KB902_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6809569.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            301..699
                     /locus_tag="KB902_002823"
     CDS             301..699
                     /locus_tag="KB902_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6809570.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT          273 a          117 c          135 g          228 t
ORIGIN      
        1 ttaaaagtat atacttggat ataatgtact tactatagaa tgagaatggt atagagggtg
       61 gcgaaatatg aaaaaaatga aaaagtataa aattagaaaa tctggcaata gcgatgtaac
      121 aactatccca ccagaagtaa aagaattcat gggtgtgcag acaggtgacg caatcagtta
      181 tgtttttcaa tctgatggtt ctgtacgaat gatcaaagca caagaagaac ctgatattga
      241 ttcattagtt gattcgatca tgaatcaata tgaagacgcg ttaaaagatt tggttgattt
      301 atgaggtatc tttcgactaa agaaattatc aaaatcaacg cgaaagttat tttacgtcac
      361 tcgccaggcg aaatgatcgg tgtaaaagat gcaaatgcat tagatatggc cgtcaaacag
      421 ccttcacaag cagtattcaa tcaagaactc tatcctgaaa tctatgaaaa agcggcgatt
      481 ttagcaatta atttagctaa aaaacatcct tttcataatg gcaataaacg aactgctctt
      541 gttgccatgt tgttgtttct tcaattgaat aattgtccag ttgctttttc tcgtcaagaa
      601 gctgttgatt ttatcataat gattaccact agttcattgg atttcgattc actaaagtcc
      661 aagataacca gttatttacg acaaaccgca ataaaatgaa cgaattaaaa actttatttc
      721 tcaattagat cagcatgtca ttaaggaata tgc
//
LOCUS       DADVXB010000278          748 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.287, whole genome shotgun sequence.
ACCESSION   DADVXB010000278 DADVXB010000000
VERSION     DADVXB010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.287"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            235..>748
                     /locus_tag="KB902_002824"
     CDS             235..>748
                     /locus_tag="KB902_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809571.1"
                     /translation="MYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILP
                     LILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEI
                     FLIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSID
                     SELLSFGIGLT"
BASE COUNT          231 a          107 c          113 g          297 t
ORIGIN      
        1 ggcttttatg atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc
       61 tcccctatta attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca
      121 tggttaactc tatatccttt atttttattg atcaagttta ctaatttagc aataggctat
      181 aacctttttc tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat
      241 gaaattacca aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct
      301 tttaggagtg tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata
      361 cttcctctta ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt
      421 atgttggcga ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact
      481 atggtaatga ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc
      541 ttcttaatta ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt
      601 ataggtccta tgattgagca gacattgtat caagatctga atagacctta tgtggatata
      661 ttacaaaaaa gagcaattta tctgggtaaa gagtttttga ttggaagtat agattcagaa
      721 ttactatcat ttggtattgg cttaactt
//
LOCUS       DADVXB010000279          746 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.288, whole genome shotgun sequence.
ACCESSION   DADVXB010000279 DADVXB010000000
VERSION     DADVXB010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.288"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>746
                     /locus_tag="KB902_002825"
     rRNA            <1..>746
                     /locus_tag="KB902_002825"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          227 a          152 c          221 g          146 t
ORIGIN      
        1 tcagtcaaag agggtaaaaa ccccgtagac gaaatgtgga agacacctag gaggatcctg
       61 agtacggcgg aacacgagaa attccgtcgg aatccgggag gaccatctcc caaggctaaa
      121 tactccctag tgaccgatag tgaaccagta ccgtgaggga aaggtgaaaa gcaccccgga
      181 aggggagtga aatagaacct gaaaccgtgt gcctacaaca agtcaaagcc cgttaatggg
      241 tgatggcgtg ccttttgtag aatgaaccgg cgagttacga ttgcatgcga ggttaagttg
      301 aagagacgga gccgcagcga aagcgagtct gaatagggcg tttgagtatg tagtcgtaga
      361 cccgaaacca tgtgatctac ccatgtccag gttgaaggtg cggtaaaacg cactggagga
      421 ccgaacccac gtacgttgaa aagtgcgggg atgaggtgtg ggtagcggag aaattccaaa
      481 cgaacttgga gatagctggt tctctccgaa atagctttag ggctagcctc ggaattgaga
      541 atgatggagg tagagcactg tttggactag gggcccatct cgggttaccg aattcagata
      601 aactccgaat gccattcatt catatccggg agtcagactg tgagtgataa gatccatagt
      661 cgaaagggaa acagcccaga ccaccagcta aggtcccaaa atatatgtta agtggaaaag
      721 gatgtggggt tgcacagaca actagg
//
LOCUS       DADVXB010000280          733 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.290, whole genome shotgun sequence.
ACCESSION   DADVXB010000280 DADVXB010000000
VERSION     DADVXB010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.290"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            25..>733
                     /locus_tag="KB902_002826"
     CDS             25..>733
                     /locus_tag="KB902_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6809572.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          259 a          126 c          139 g          209 t
ORIGIN      
        1 aagaattata aggagtgagt acaaatgacc tatacccatc ttacaacgga tgaacttgta
       61 ataatagagt cttatttcaa aatgaatcaa tctgttgcta aaactgccca ttgcttgaat
      121 cgttcaagac aaacgatcca taaagtatat ctgttcttca agcaaggaaa atcagcctta
      181 gaatattatc aacagtataa gaaaaacaaa tcaaactgtg gtagacgtcc gcttgtttta
      241 cccgaggaac aatcagaata tattcaaaga aaggttgttc aaggatggac acccgatgtg
      301 attgttggtc gtgcagcgtt tcctattagt tgttctgctc gtaccattta tcgtatgttc
      361 aaaaaggggc tatttgattc ttctgactta ccgatgaaag gcaagcgtaa accgaatgga
      421 catcaagaaa gacgtggaaa acaaactttc cgccgctcta ttcatgaacg tgaaaaggat
      481 tatagccaat tctcaaatga gtttggtcac cttgaaggtg acactatcgt aggtctgaaa
      541 cataaaagtg ctgtaattac cttagttgaa cgattatcaa aagttatcat cacattgaaa
      601 ccgtgtggta gacaagcgat tgatattgaa aaaaaattaa atcaatggtt tgaatctgta
      661 ccgaaaaacc tattcaaatc catcactttt gattgtggaa aggaattttc aaattggaaa
      721 cagatcagta atg
//
LOCUS       DADVXB010000281          731 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.291, whole genome shotgun sequence.
ACCESSION   DADVXB010000281 DADVXB010000000
VERSION     DADVXB010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.291"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="KB902_002827"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="KB902_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6809573.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="KB902_002828"
     CDS             complement(481..675)
                     /locus_tag="KB902_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809574.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DADVXB010000282          711 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.292, whole genome shotgun sequence.
ACCESSION   DADVXB010000282 DADVXB010000000
VERSION     DADVXB010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.292"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            86..454
                     /locus_tag="KB902_002829"
     CDS             86..454
                     /locus_tag="KB902_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBB6809575.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
BASE COUNT          255 a          116 c          108 g          232 t
ORIGIN      
        1 attacttgtg ttttgttcgt tttttataca taactattgt ttttctggta aaataaatca
       61 aaccacttaa tggaggcgtt ttagaatgga aaaatttcag ccgatcatca atcaaatcaa
      121 agaaaaagaa catcaacaaa agatcaaaga cctttttgct aagataacag aaacgtatcc
      181 ccagctagac acaactgtaa aatggaacca acctatgttt actgaccatg gtacctttat
      241 tattgcattt agttttgcta aaaatcattt ttctatcgca ccggaaaaag cagcgattcg
      301 tgcccttgaa aaaaatatcc aagaagcagg ctacgtatat acggataacg tcatcaaagt
      361 tccttggaaa agtgtaatca actgggaatt gattgaacaa ttgatttcat ttaatattga
      421 agataaaaaa ggtcatgata aattttggcg ataaagcttt atacgaataa accttttact
      481 ggcgaggaaa ctattcatca ccttatacag gttttgttca atcctatcct ttttatcatc
      541 cctggttaaa cacttaattg acaaagtatc tgctattttt ataaggagtc tttcttgtgc
      601 tgaaaaaaat cactgattga atggctttga attttctaca tagtaaaatt attttttcag
      661 caattttcct gcaaaacttt tgaataagga aaaaatacga gaaaatatca g
//
LOCUS       DADVXB010000283          701 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.293, whole genome shotgun sequence.
ACCESSION   DADVXB010000283 DADVXB010000000
VERSION     DADVXB010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.293"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>701
                     /locus_tag="KB902_002830"
     CDS             <1..>701
                     /locus_tag="KB902_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6809576.1"
                     /translation="SVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFF
                     DKKQWRYALKISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVI
                     WMSTNNAWVPWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDY
                     YSGLSLVVPITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRL
                     GIIAAGYTTVFTYFLL"
BASE COUNT          218 a           90 c          133 g          260 t
ORIGIN      
        1 tctgtagctt tgatgcagac attatatttt gatgataaat atgttggcag agtagtcggc
       61 ggaacactgt catttgtgtt gataggttta gtaatttatt taagaataat gataaagggt
      121 gctcattttt ttgataaaaa acagtggaga tacgctttaa aaatctcttt gccgctaatc
      181 ccacattcct tagcaaatat agttttagca caattcgata gaattatgat taattcttat
      241 ttaggtcctg ctgcgggggg aatatattcc tacattagta acataggtat tattctaagc
      301 gtaatatgga tgtctactaa taacgcctgg gttccatggt tctatggtga gatgagtaaa
      361 aataatgaaa aaaaagtgaa gaaagttagt aactattatt tagtagtctt tactttgatt
      421 acgatgattg taatggtagt ttcgattgat ttagcaaaat ttatggctcc gaaagactat
      481 tattctgggt tatctttagt ggttccgata accttaggct atttctttca gtttttatat
      541 agtttaccag ttaatgctga attttatgag aaaaaaacat cgtttattgc gattggtaca
      601 gtagcaagtg ctatagttaa tatactatta aacatgattt tcatacctag gttaggaata
      661 attgctgctg gatacacaac cgtatttacg tattttttac t
//
LOCUS       DADVXB010000284          699 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.294, whole genome shotgun sequence.
ACCESSION   DADVXB010000284 DADVXB010000000
VERSION     DADVXB010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.294"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            133..>699
                     /locus_tag="KB902_002831"
     CDS             133..>699
                     /locus_tag="KB902_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6809577.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQS"
BASE COUNT          212 a          137 c          131 g          219 t
ORIGIN      
        1 tccttctatc ggctctatac tttttgatgt tggtgaactt caccaacatc ttttttgtat
       61 aaaaaaatat agaaaagaca ccctgaaatc ctttagaatt aatttggcta ccaattcata
      121 ggaggattca agatgtctca tactcagctt atcaaagata ccctaaatat tctagaccta
      181 aatatctatt tcgaggaaaa ttgtttaact aaagaaaaat acaaagggca aatttgcttg
      241 atttacaaag gaactcttct gtacaagcca gaagagtgtt cccattgtct ttgtgtcgtc
      301 ccctctagga tcattcgttg ggggacgaca accgttcggt tgttactgaa tgatgtgtct
      361 gagtatcgca cttatctgga gctgaagaaa caacgattta aatgtaagtc ttgccaaaga
      421 acattcgtag cggatacctc tgttgctgaa aaacactgtt tcattagtca aaaagttcgt
      481 tggtctgtca ttgctcgctt aaaagagaat acttccatga cggaaatcgc tcgtcagaaa
      541 aatatttcca cttcttcggt ctatcgtgtc atgaagcgat tctaccgccc attgaatcct
      601 ttcaaacaga ctttgccaaa ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt
      661 gccagtgcaa tgagttttat catgatggac ggacaaagc
//
LOCUS       DADVXB010000285          689 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.295, whole genome shotgun sequence.
ACCESSION   DADVXB010000285 DADVXB010000000
VERSION     DADVXB010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.295"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..689
                     /locus_tag="KB902_002832"
     rRNA            <1..689
                     /locus_tag="KB902_002832"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          147 c          221 g          149 t
ORIGIN      
        1 cactaatcgt ggtgggagac agtgtcagat gggcagtttg actggggcgg tcgcctccta
       61 aaaggtaacg gaggcgccca aaggttccct cagaatggtt ggaaatcatt cgaagagtgt
      121 aaaggcagaa gggagcttga ctgcgagacc aacaagtcga gcagggacga aagtcgggct
      181 tagtgatccg gtggttccgc atggaagggc catcgctcaa cggataaaag ctaccctggg
      241 gataacaggc ttatctcccc caagagtcca catcgacggg gaggtttggc acctcgatgt
      301 cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc gcccattaaa
      361 gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcgggc
      421 gttggaaatt tgagaggagc tgtccttagt acgagaggac cgggatggac ttaccgctgg
      481 tgtaccagtt gttctgccaa gggcattgct gggtagctat gtagggaagg gataaacgct
      541 gaaagcatct aagtgtgaag cccacctcaa gatgagattt cccatttctt taagaaagta
      601 agatccctga gagatgatca ggtagatagg tcaggagtgg aagtacagtg atgtatggag
      661 cggactgata ctaatcgatc gaggactta
//
LOCUS       DADVXB010000286          680 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.296, whole genome shotgun sequence.
ACCESSION   DADVXB010000286 DADVXB010000000
VERSION     DADVXB010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.296"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            211..525
                     /locus_tag="KB902_002833"
                     /pseudo
     CDS             211..525
                     /locus_tag="KB902_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
BASE COUNT          273 a           84 c          123 g          200 t
ORIGIN      
        1 taagtaataa accaaattta aactttatat tataataatg aagcttaatc ttctttatag
       61 agaattgggc tatttttaat ggcaaagagg ggaagaagat gtttcaaaac aaaggacaac
      121 gctatgttgt aaaaggagta aaggaatctt actggaatca aaaatcttta ttgagaaaat
      181 tatctttgaa tctaagcaca aagaaatgaa ggtacactag atagcaatga agatatcttt
      241 gtcattaaac gtcgctattt tacacaagta agtgatgatt tgattcatgt cttttccaat
      301 gagtggtttg tttctgagaa aaaattacat gtttctaatc tgcaatatat gccaggtgaa
      361 gatccaattc ctaatatgaa agcaattatc aacagtaagg attacgaagg atataaagct
      421 aaacatccag aagcgaagcc atttaaatac ccacaagaaa tgaagcaagc atggcgcaaa
      481 atgttagatg atgagctgat tccacttgaa aatgaattga ggtaaacgag aagaattcaa
      541 taaactggat gataaaaata taatatgact ataaattggt tacagcttca acctataagt
      601 tgtaataaat tagcctaaaa gtaatttatt aatgatgagg tgaatttgat tggtacaaca
      661 agatatatca cttagagagg
//
LOCUS       DADVXB010000287          679 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.297, whole genome shotgun sequence.
ACCESSION   DADVXB010000287 DADVXB010000000
VERSION     DADVXB010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.297"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..339
                     /locus_tag="KB902_002834"
     CDS             <1..339
                     /locus_tag="KB902_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809578.1"
                     /translation="IRADGEPLTIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEAL
                     EHENDNLKQLNAKLMLNDVAIKQENTALKEKADSLAQINSKTMLASLQNSKDIAEIKK
                     QLNPESEGGE"
     gene            341..478
                     /locus_tag="KB902_002835"
     CDS             341..478
                     /locus_tag="KB902_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6809579.1"
                     /translation="MFSFSDVKMMFDWSCFTEEQVREFVPLCITDEEADKIISKEESA
                     S"
     gene            516..>679
                     /locus_tag="KB902_002836"
     CDS             516..>679
                     /locus_tag="KB902_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809580.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLES"
BASE COUNT          243 a          106 c          139 g          191 t
ORIGIN      
        1 attcgtgctg atggcgaacc gctaacgatt gctgatcaga tgtttgatcc taaactgaac
       61 caatggattg ttttagcgaa cacactggat cacaacgatt taaacaatct caaagcgatg
      121 tatgaggctc tggaacatga aaacgacaac ctaaaacagc taaatgccaa actcatgcta
      181 aacgatgtag caattaaaca ggaaaatact gcattgaaag aaaaagcgga tagtttagca
      241 caaatcaatt caaagacaat gcttgcttcg cttcaaaaca gcaaggatat tgcagaaatt
      301 aaaaagcaat taaatccaga atcagaagga ggtgagtagt atgtttagtt ttagcgatgt
      361 gaaaatgatg tttgactgga gctgttttac agaagaacag gttcgtgagt ttgtgccatt
      421 gtgtattaca gacgaagaag cagataaaat cattagcaaa gaagagagcg catcttaatt
      481 gatgtgcttt ttaatttgat tcaaggagtt gtcacatgat taatttaggg gaatggggaa
      541 caatcgcagg atcaatcact gcgattgttt ctttgatttt attagtaata aaaccaatta
      601 ctgcatcttt ctcgaagatt actgagactc tttcaaaagt aagtcacaat ttagatttgc
      661 tgactaaaga tttagaatc
//
LOCUS       DADVXB010000288          679 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.298, whole genome shotgun sequence.
ACCESSION   DADVXB010000288 DADVXB010000000
VERSION     DADVXB010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.298"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..339
                     /locus_tag="KB902_002837"
     CDS             <1..339
                     /locus_tag="KB902_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809581.1"
                     /translation="IRADGEPLTIADQMFDPKLNQWIILANALDHNDLNNLKAMYESL
                     ENENGDLKQINAKLMLSDVAIKQENTALKEKADSLAQINSKMMLASLQNSKDISEIKE
                     QLNPASKGGE"
     gene            341..478
                     /locus_tag="KB902_002838"
     CDS             341..478
                     /locus_tag="KB902_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6809582.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            516..>679
                     /locus_tag="KB902_002839"
     CDS             516..>679
                     /locus_tag="KB902_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809583.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLES"
BASE COUNT          244 a          101 c          135 g          199 t
ORIGIN      
        1 attcgtgctg atggcgaacc gttaacaatc gctgatcaaa tgtttgatcc taaattgaat
       61 caatggatta ttttagcgaa cgcactagat cacaacgatt taaacaatct caaagcaatg
      121 tatgagtcgt tagaaaatga gaacggcgat ttaaaacaga tcaatgccaa actcatgcta
      181 agcgatgtag caattaaaca ggaaaatact gcattgaaag aaaaagcgga tagtttagca
      241 caaatcaatt caaaaatgat gcttgcttcg ttacaaaata gcaaagacat ttcagaaatt
      301 aaagagcaac taaatccagc ttcaaaggga ggtgagtagt atgtttagtt ttagcgatgt
      361 gaaaatgatg tatgattggg gctgtttcac taacgaacaa gtaatggttt tcgttccgtt
      421 gtgcattact gaagaaaaag cagataaaat cattagcaaa gaagagagcg catcttaatt
      481 gatgtgcttt ttattttgat tcaaggagtt gtcacatgat taatttaggg gaatggggag
      541 cgatagcagg atcaataacc gctatcgttt ctttgatttt attagtaata aaaccaatta
      601 ctgcatcttt ctcgaagatt actgagactc tttcaaaagt aagtcacaat ttagatttgc
      661 tgactaaaga tttagaatc
//
LOCUS       DADVXB010000289          652 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.300, whole genome shotgun sequence.
ACCESSION   DADVXB010000289 DADVXB010000000
VERSION     DADVXB010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.300"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(134..511)
                     /locus_tag="KB902_002840"
     CDS             complement(134..511)
                     /locus_tag="KB902_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809584.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
BASE COUNT          203 a          114 c          113 g          222 t
ORIGIN      
        1 accaaaaaag aagcagatcc gttagcggtt ctgcttcttt tagtttatta tattttctta
       61 tcaataatag gaacctgatt ttaaaagcgg ctacctcttt accgtgcctc tttacataca
      121 aaaaatagag gaattaagcg taaatggctt ggctattata actaaaatgc tggttatgga
      181 gatgttgcag caagttttcg agaaaagcgt attccatctc ttgtccattg aataagatct
      241 ggatacgata atgatttttg aaacgcttct gttcatgaat ctgactgatt gaaagttcgc
      301 ctttgtgttc tgtctgataa agaaaagtcc ttttacggca ttcagcacag cgcttggttg
      361 ctcggcggat ttttcggaat gtataaaaac tagtatcttt attgcataaa taaacgtctt
      421 tgatcgacag caaatcatta tatagacagg aacgttcttc agctgttaat tctgataaaa
      481 aaagctgacc ttgttttatt gcatcttcca tcggcaagtg cctcctcgaa cccattatcc
      541 aaatttttag ttaattctaa tataccatca ttaagtataa atgtaaacgc ttgttgatgg
      601 tataagattt tcgtttctga taaaacacga acattaaaag aatctaatgc ct
//
LOCUS       DADVXB010000290          634 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.301, whole genome shotgun sequence.
ACCESSION   DADVXB010000290 DADVXB010000000
VERSION     DADVXB010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.301"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(100..184)
                     /locus_tag="KB902_002841"
     tRNA            complement(100..184)
                     /locus_tag="KB902_002841"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(148..150),aa:Leu,seq:caa)
     gene            complement(202..273)
                     /locus_tag="KB902_002842"
     tRNA            complement(202..273)
                     /locus_tag="KB902_002842"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(239..241),aa:Gln,seq:ttg)
     gene            complement(283..355)
                     /locus_tag="KB902_002843"
     tRNA            complement(283..355)
                     /locus_tag="KB902_002843"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(320..322),aa:His,seq:gtg)
     gene            complement(417..501)
                     /locus_tag="KB902_002844"
     tRNA            complement(417..501)
                     /locus_tag="KB902_002844"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(465..467),aa:Leu,seq:caa)
     gene            complement(522..592)
                     /locus_tag="KB902_002845"
     tRNA            complement(522..592)
                     /locus_tag="KB902_002845"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(558..560),aa:Cys,seq:gca)
BASE COUNT          195 a          147 c          136 g          156 t
ORIGIN      
        1 tttatgataa tacttgtatc gaattgattt ggaggtaatt acataaaaac aaaaaaaata
       61 tagcaactct ctataagaaa gttgctatat tgataattat accggcggcc ggggtcgaac
      121 cggcacgtcc tcaacggaca ctggattttg agtccagcgc gtctgccaat tccgccacgc
      181 cggcaaattt aaaaataata actggggtag ctggattcga accaacgcat gagggagtca
      241 aagtcccttg ccttaccgct tggctatacc ccaagaataa agggcgaatg atgggaatcg
      301 aacccacgaa tgccggagcc acaatccggt gcgttaacca cttcgccaca ttcgccatca
      361 taaaagatgt tatttaattt ctcaataaaa aactaagatg aagacatctt agtcaatacc
      421 ggcggccggg gtcgaaccgg cacgccctca acgggcactg gattttgagt ccagcgcgtc
      481 tgccaattcc gccacgccgg caagttgatt tattagtact aaggcggtaa ccggatttga
      541 accggtgatg aaggttttgc agacctctgc cttaccactt ggctataccg ccattatact
      601 attatcaatc tataaaataa agaataaatt atag
//
LOCUS       DADVXB010000291          627 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.302, whole genome shotgun sequence.
ACCESSION   DADVXB010000291 DADVXB010000000
VERSION     DADVXB010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.302"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(1..627)
                     /locus_tag="KB902_002846"
                     /pseudo
     CDS             complement(1..627)
                     /locus_tag="KB902_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          184 a          122 c           93 g          228 t
ORIGIN      
        1 ataagctctt cttccgtgtt acctttatat atttcgtacg cgctagattt aattgggaac
       61 gtcgtacctt tatttgcaat attcttaccc aacgatgttt tacctaccca gtaagggtca
      121 tctagtaagt ttggctgata cggagtggct gttgagcctt cttcgatttt gatgtcgtac
      181 aatttaaatc caccatttat tttatccctg ttagaaaaac taacactaat ataaaaacga
      241 tctaaatttg tgatttgata attaacgtta gctgtgcctt tgattgttat ttctttccct
      301 acatcatcta ttgtaatagt tgtattattt gcttccaatt aatatatttt ctcctggtga
      361 tgtacgatat accaaacgta atttattaat agctcctgta gttccttcat caaatcgaac
      421 ttttgcactc agagtatatg ttttgccact agcaagctga ggtgtattaa tacgcgtaaa
      481 catatcaatg tcccctgtac catcagacat aaaatgtaac attccgttaa cattagttag
      541 tgacccatgg taacccatat aaaaatcgct agattccaat ttatttacaa ataagttggg
      601 attcccacta taatcatagt caccgaa
//
LOCUS       DADVXB010000292          623 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.303, whole genome shotgun sequence.
ACCESSION   DADVXB010000292 DADVXB010000000
VERSION     DADVXB010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.303"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>623
                     /locus_tag="KB902_002847"
     CDS             <1..>623
                     /locus_tag="KB902_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809585.1"
                     /translation="FGNYDYSGNPNLMANINADSFSQGSGALSVVDDGDEVVITLDPN
                     HKLEIFKAKSQPALVVGKTYTMSVEIMLEDDFTGDPSNISLRYIKMPSWLTVLYTPYT
                     LTNTKGVWQKLTVTAKMTTAIDNAESWFIMLQNKDANNSLSGKLRLRHAKLEEGSTAT
                     PFQPNLLAEPYNMCREYPNENIADPKVKFPIESGDHQIYQGYTEEEL"
BASE COUNT          221 a          120 c          119 g          163 t
ORIGIN      
        1 ttcgggaact atgattatag tggaaatccg aatttgatgg ctaatataaa cgctgatagc
       61 ttctcgcaag gtagtggtgc cttatctgtt gtagatgatg gtgacgaggt agtgattacg
      121 cttgatccaa accataaatt agaaatattc aaagcgaaaa gtcaaccagc tctggtagtg
      181 gggaaaacat ataccatgag tgtagaaatt atgttagaag atgatttcac tggagaccct
      241 agtaatatat ctctaagata tattaaaatg cccagctggt taacagtact atatacgcct
      301 tatacattaa ctaatactaa gggtgtatgg caaaaactaa ctgttaccgc taaaatgact
      361 actgcgattg ataacgctga aagctggttt ataatgctac aaaataaaga cgctaataac
      421 agcctatccg gcaaactacg tttgagacac gctaaactcg aagaaggctc aacagctaca
      481 ccattccaac ctaacttatt agcagaacct tacaacatgt gtcgcgaata tcctaacgaa
      541 aatattgccg atcctaaagt taagttccca atcgaatctg gcgaccacca aatatatcaa
      601 ggctacacag aagaagagct tat
//
LOCUS       DADVXB010000293          587 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.304, whole genome shotgun sequence.
ACCESSION   DADVXB010000293 DADVXB010000000
VERSION     DADVXB010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.304"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(150..515)
                     /locus_tag="KB902_002848"
     CDS             complement(150..515)
                     /locus_tag="KB902_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809586.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          230 a           79 c          111 g          167 t
ORIGIN      
        1 ctgcaattat tacacaactg tttttagtgt ttggagagaa gaaaagaagt aaaaaataga
       61 aaaactagtg atagttttgg tgatataaga aaaacatata tgtataaaaa gaagaaagta
      121 gcttctcttt gtacatatat ggtttgtttt tatggatgcc gagctttttt ataagataag
      181 gctaccgccc ataacgaccc aaggatttgt ggaactaagt aaatacctgc aagaagcaag
      241 atcagctggg tcggttttaa aggatgatag aagtaacgcc attcagtaaa attggcgcaa
      301 aataaatagg aagtgacagt agatataata ttggcaatga ataaagatat aatacgcctg
      361 ttcctttgaa aataatatcc agcaaaaaga gataaaaata tcaatgtgat gaacccgctt
      421 acggaatgat aacgaaaatc aagcagtaag gcgaaatgca cataaggaac aaaagataaa
      481 agcaacggaa ggtttttcca gcaagttttt atcatctttc atcaccacct aacaagtgtt
      541 attattttgt tagttttatt gtaaattgaa tcctgcaata atcaatt
//
LOCUS       DADVXB010000294          569 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.305, whole genome shotgun sequence.
ACCESSION   DADVXB010000294 DADVXB010000000
VERSION     DADVXB010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.305"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..372)
                     /locus_tag="KB902_002849"
     CDS             complement(<1..372)
                     /locus_tag="KB902_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6809587.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYS"
BASE COUNT          170 a          106 c           83 g          210 t
ORIGIN      
        1 agaataactc acgtgatgct gtttagcaaa attttctact gagatatatt tttcctgaaa
       61 gaaagccaat accattttca tagataaaga atccgttata taacgagata acagagcttt
      121 gctagaacat tttccattaa tttccagaca tatatccaat tcactgacgg ttactcgcaa
      181 atttttctct agatcgaact tttgtaaatc atgtttcagc ttatcgatcg tttttttcaa
      241 gagaaatgtc gatagcgaca actcttcttg aacattcgat attgactctg ataaatttga
      301 gcttgcttct aaatatttaa gtaatgaata acttctgtga tcttctttgc ttaaaaaaaa
      361 ctcataattc attagtcatc agctctttct acgtatatta ctttccatgc attcaccaac
      421 tagctgggga taaaactgat ttcctggatc cgagtcactg ttgtcagcga ttcttgtttg
      481 tataatatac atcgtcctgt ctttctttaa cattttggag agcgttttat ttggcctttc
      541 tcgcgatcaa acctgttata agaattata
//
LOCUS       DADVXB010000295          563 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.306, whole genome shotgun sequence.
ACCESSION   DADVXB010000295 DADVXB010000000
VERSION     DADVXB010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.306"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..479
                     /locus_tag="KB902_002850"
     CDS             <1..479
                     /locus_tag="KB902_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6809588.1"
                     /translation="SFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERKKVIVPK
                     EIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGLIAEPSN
                     WSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLDVTEK"
BASE COUNT          192 a           84 c          142 g          145 t
ORIGIN      
        1 tttcttttaa gccaatctac ggccgttctg gcaagctaga aacagcgtac tggggcagtc
       61 gtgccagtga gcgccaagtg cgactgtaca acaaaaagct agagcaggaa cgaaaaaaag
      121 taatcgtgcc aaaagaaatc gatacgtggt ggcggttaga aatgcagcta agacgtggca
      181 aagcaacgga ttggcatgcg atggttcagg aaagcttaga tagttttgca agcccgcatt
      241 ttttgccgat tgatataaaa cctattgata aaatagttat tgatggtttg atagctgagc
      301 cttctaattg gtcgataatt gctagacata caaaatataa atatcggaat ttgctgaagc
      361 aagaaagtca aaatgatgag ttaacgaatc atttacgaga gacttttaag gaatctgcag
      421 acgaattaaa aaaagaattg gatacgtggc ttttggggtt ggatgtgaca gagaagtgat
      481 accgaataag aaaagtcaga tgagtgagag tggatttgcg tcaatgttta gtgacgtaaa
      541 ttcacgataa gcgaatattt tgc
//
LOCUS       DADVXB010000296          559 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.307, whole genome shotgun sequence.
ACCESSION   DADVXB010000296 DADVXB010000000
VERSION     DADVXB010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.307"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            127..>559
                     /locus_tag="KB902_002851"
     CDS             127..>559
                     /locus_tag="KB902_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HBB6809589.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSI"
BASE COUNT          216 a           65 c           97 g          181 t
ORIGIN      
        1 ataaatgtcc tttcctattc ttaaaatgat gtttgtactt acttaaatta ggtataatta
       61 gtatatgttt tgtgagaaat ttagacttac aataagcagt gaatttataa tcaacgtata
      121 ggagacatgg atgaaatgaa actaattggt atagatttag acggtactct tttgaattct
      181 gaccagagca ttagtcaaaa aaatgcaaga acaatgaaac atttaccgga agactgtttt
      241 ccattcattt gttctggaag agaagtagaa gacattaata atattctcaa aaaatctggt
      301 ttaaggatac cagcagtagg gttaaatggt tctgttggat ttgatggaga aaaaaagata
      361 tttgagtctt ccttcgataa aaatgatgta aaaaaaattg attctgtcct atcgaaattt
      421 ccaaccaaaa tatatacaaa tctcggaagt tatgaatctc agaattataa aaataaaatg
      481 aaaaaaattt ttcacgaggt agggagtgaa ttttctatca aagagctaaa ctatgagctt
      541 gagtatgaaa aatctattt
//
LOCUS       DADVXB010000297          546 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.308, whole genome shotgun sequence.
ACCESSION   DADVXB010000297 DADVXB010000000
VERSION     DADVXB010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.308"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            49..444
                     /locus_tag="KB902_002852"
     CDS             49..444
                     /locus_tag="KB902_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809590.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT          242 a           51 c           88 g          165 t
ORIGIN      
        1 cctttttaaa tatatacgat aaaataagta tatgaattgt aaaaggacat gatgattatg
       61 gaagaaatag aatggaataa tctgactcaa aataataaaa ataattctgg atgtggaatt
      121 atctttatgt ttgttatagt tttgggaata gtagtacttt taataactgt caagatagta
      181 gattactttg cgaatactcc tgaagaacaa atacagagaa aacttcctga gtttgaaaga
      241 gtaccacctt atgatccaag agataattca tttcaagtaa aaaaattaaa agagtctcca
      301 aatgaaatgt ggtttgaagt tacagttgaa tcaagcgact tcaaagaaaa aaagaaagaa
      361 tacaattata ttgtaaaggc aaaagtatca aaaagattta tttttaaccc taaattagaa
      421 atatatagtg ttgtaataga ataatagtgt taaaaaaatt gtaaaagtta aagaagtcaa
      481 attctgatgt gaaaaataaa atataccatg gaagacataa aagaaaaact ggataactag
      541 tttatt
//
LOCUS       DADVXB010000298          527 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.309, whole genome shotgun sequence.
ACCESSION   DADVXB010000298 DADVXB010000000
VERSION     DADVXB010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.309"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT          189 a           82 c           84 g          172 t
ORIGIN      
        1 tatatttgaa aagttttact ttgattttta aatagaaaga catttgggtt aaattgtgag
       61 ataataataa agaagagttt aaagcgcacc ccaaaccact tccccataag tgtgttacgc
      121 tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga aaaaaagtga
      181 gaaaaaaggc ttacaattgg agtggtagtt aattagtgac ttatttttga ttttatagca
      241 ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat
      301 atctcctttc acaagtatgg tgataaaatt cgttccgggc taccttttta ggtagcctac
      361 tttaatcttt atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat
      421 gatcgctacg tgcgtccggc acgtcagtca tgaatcggct acactagact agacagaaaa
      481 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatg
//
LOCUS       DADVXB010000299          517 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.310, whole genome shotgun sequence.
ACCESSION   DADVXB010000299 DADVXB010000000
VERSION     DADVXB010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.310"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            198..439
                     /locus_tag="KB902_002853"
                     /pseudo
     CDS             198..439
                     /locus_tag="KB902_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
BASE COUNT          210 a           59 c          103 g          145 t
ORIGIN      
        1 ctacaatgcc gttgtaaaaa ttggggaaaa gggatatatt gattttatat ctttctcaaa
       61 ataaacataa aagcccttta aacagggctt ttatatatta atcacttatc acaaatcaca
      121 aatcacttat cacaaatcac ttgtgatttg tgattgttga tgataaaata agaataagaa
      181 gaaatagaaa gaagtgagtg attgtgggaa atttaggcgc acaaaaagaa aaacgaaatg
      241 atacaccaat cagtgcaaaa aaagatataa tgggagataa gacggttcgt gttcgtgctg
      301 acttgcacca tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta
      361 tggaaataag acttagaagc aaacttaaga gtgtgttgat agtgcagtat cttaaaattt
      421 tgtgtataat aggaattgaa gttaaattag atgctaaaaa tttgtaatta agaaggaggg
      481 attcgtcatg ttggtattcc aaatgcgtaa tgtagat
//
LOCUS       DADVXB010000300          507 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.311, whole genome shotgun sequence.
ACCESSION   DADVXB010000300 DADVXB010000000
VERSION     DADVXB010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.311"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..131)
                     /locus_tag="KB902_002854"
     CDS             complement(<1..131)
                     /locus_tag="KB902_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6809591.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     "
     gene            complement(142..348)
                     /locus_tag="KB902_002855"
     CDS             complement(142..348)
                     /locus_tag="KB902_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6809592.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          148 a          111 c           69 g          179 t
ORIGIN      
        1 gctacttgtg agctaccttc atttgcgccc aaattaaatt cattgttgat agtataggca
       61 aatccgttaa ttggcaataa aaaaagagcc gttaacaggc tcatcgcagt aatagtaatt
      121 ttctttttca tatctatcct cctatttatc tgatgaaatt ttcttatacg ttcgatttga
      181 tacacctaaa atactcccta gaaatgctcc aaaacctgta ataatcatca ccgttatatc
      241 tgtgtaccgc cagttaacac cttttccgac aagaccgaca aaagtcgcta aagcggggat
      301 aactactata gcgatccatt tcaaaatatc aaaggttcta ttgttcatac tatccacctc
      361 ccttcattgg ttgggctact ttctttttca atcgcttgtt ttcttctatc aatatttctc
      421 tttctgaaag caaggcatca atttgcccgt ccagttgttc aattttatct ttcttaattg
      481 tcaaattaag ttagacagat catcaat
//
LOCUS       DADVXB010000301          505 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.312, whole genome shotgun sequence.
ACCESSION   DADVXB010000301 DADVXB010000000
VERSION     DADVXB010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.312"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            136..435
                     /locus_tag="KB902_002856"
     CDS             136..435
                     /locus_tag="KB902_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6809593.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          194 a           61 c           99 g          151 t
ORIGIN      
        1 aaataaaaat cgttgccata acagtgtatt gaaaggtttt aacaatccag taatgattta
       61 aaaaaatcta gatgtagcgt atactttgtt tatagaatgt agtgggaaga aatatatttt
      121 tgggaggaaa tcgtgatgtc taaaagtgaa gaaatagaaa acatggtact aaaattatat
      181 gatctcgttt taaatccaga gatcaaagaa aaggaacgta tacttttgat agacgcaaag
      241 acaggcttag aaaaaggtca gtattatcct aaagtcataa ataatttgga acgtagttta
      301 cgtccgttag caatcagggg agaattgtct aaaccagtat caccgtttta tatggagata
      361 tcaacaatag gaaaatttga aaaagaatta ggtcgaggaa tggcttcggc accgattact
      421 tttgggcatt tataaaaacg agttattcat ctcaatgaat taaaaagtat agtcaatctc
      481 ataatgcagg ctaggttcat ttatt
//
LOCUS       DADVXB010000302          505 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.313, whole genome shotgun sequence.
ACCESSION   DADVXB010000302 DADVXB010000000
VERSION     DADVXB010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.313"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>505
                     /locus_tag="KB902_002857"
     rRNA            <1..>505
                     /locus_tag="KB902_002857"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          154 a          113 c          144 g           94 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagac
//
LOCUS       DADVXB010000303          490 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.314, whole genome shotgun sequence.
ACCESSION   DADVXB010000303 DADVXB010000000
VERSION     DADVXB010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.314"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            2..>490
                     /locus_tag="KB902_002858"
     CDS             2..>490
                     /locus_tag="KB902_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6809594.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYI"
BASE COUNT          184 a           71 c          110 g          125 t
ORIGIN      
        1 gatgagtgaa aaggaacaac ctttgaaaaa tagaagtgat aatacgcttt ttaatacctt
       61 atacaaaata aatgtgaaag atgttactga aaaacgaaat aacctcactt atctttcgtg
      121 ggcatgggct tgggcagaag ttagcaaagt gtgtgaggca gtagattatg aaatctatca
      181 tgatccagaa acatatctgc cgtatgtctt tgataagaaa acagggtaca tggtttttac
      241 cagtatcaca gtcaacggag taaagcgtga catgtggtta ccagtcatgg atggtgcaaa
      301 caaggcaatg aaagatgagc catataccta cgaagtcaat gattatcagt ggaataacga
      361 aacgaagaaa aaagagattg ttggaaaaat cgaaaagcga gttgaagcag caactatgtt
      421 tgatatcaac aaaacgatca tgcgctgtct tgtaaaaaat ctagcaatgt ttgggctagg
      481 gctatatata
//
LOCUS       DADVXB010000304          489 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.315, whole genome shotgun sequence.
ACCESSION   DADVXB010000304 DADVXB010000000
VERSION     DADVXB010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.315"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT          161 a           97 c           57 g          174 t
ORIGIN      
        1 gctaaatcac tctacaataa cggcgaaagc acaaaaaata aaaaaattat tacgttatta
       61 aaaaaacaga tgaaagatca ggttttatta gatctcattc tttcatcact tgaagggatt
      121 taatgaacta ctttttcctc tttgtcgttt ttatacattc gtattccttc aaacagtagg
      181 atagcctctt tcaatgcttg atatttgaac tgtccgttac ttaaaaattt agatgtgccg
      241 ccctcttcct agaacatatt cttttttact ttttcattaa ttgacagacc aatcgaacga
      301 aactgtaaat ttcgatagga taatgattgg tcaaactcat tcattttcaa gacatctcga
      361 ttcatattca agataggaat ctttttatca acatcacttt attcgtattt tcctctacca
      421 taaaagcttc acgctccaca aaattgtttt atacactact attcagccca ttcaacgacc
      481 aatgaattt
//
LOCUS       DADVXB010000305          484 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.316, whole genome shotgun sequence.
ACCESSION   DADVXB010000305 DADVXB010000000
VERSION     DADVXB010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.316"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            1..481
                     /locus_tag="KB902_002859"
                     /pseudo
     CDS             1..481
                     /locus_tag="KB902_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          170 a           85 c          103 g          126 t
ORIGIN      
        1 actggtaaag caaacaatta taccgatggg aaagtatcgg agattaattc gcagttgact
       61 gcttcaatta atgaagtagg acaccacagc taaggatgct caaacaaaag cgaatgctaa
      121 tgcgactgct atagatgaat tagacaataa gatcgatgaa cgcattaatg atacagctac
      181 taccacatta acagttacaa acgggaatac cggatcagca aagctttatc gtgaaggaaa
      241 aacagtttct atatattttg tggctttaaa cggaaaaagc agtggtggaa atggttcaac
      301 gatactaaca attccagaag gctatcggcc accaattagt tttgagcaac tggttggctc
      361 gatagaccgt tctactttga acagtgctca gttatctatt ggtgcagatg gagccattaa
      421 atggcgaaga aactcaagtt atggatcgga ttataccttt gcaattactt acacgattta
      481 gaaa
//
LOCUS       DADVXB010000306          479 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.317, whole genome shotgun sequence.
ACCESSION   DADVXB010000306 DADVXB010000000
VERSION     DADVXB010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.317"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..452
                     /locus_tag="KB902_002860"
     CDS             <1..452
                     /locus_tag="KB902_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809595.1"
                     /translation="KLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAAC
                     PNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNAL
                     HYSYSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          171 a           94 c           84 g          130 t
ORIGIN      
        1 aaaaattgaa gcgctattgg aaactcctac aaaaagaaga agcaaagtta aactatgaaa
       61 aacgggtttg gcgtgccagt tttaaagatt atttgactga aagtgagatt gccgatcgac
      121 tgttagctgc ttgtcccaac ttacgccaag gctatcagtt ataccaagac attctttatg
      181 cggtaaagaa aagagatcag tcactatttg aggattgttt aactagagac attagcggtc
      241 tgccagaaac ctatacaacc actttacgaa cgtttaaaaa gtttctgcca cagatccaaa
      301 atgcgcttca ctacagctat tcaaacggac cattggaatg cttaaacaac cacatcaaag
      361 tattaaaacg caatgcgtac ggctttcgca acttttacaa tttcaaacta cgaattatga
      421 ttcgtcatgg caaaacattt ttaaccaaat aaacagaaca gaaagaggtt ttcttcttt
//
LOCUS       DADVXB010000307          473 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.318, whole genome shotgun sequence.
ACCESSION   DADVXB010000307 DADVXB010000000
VERSION     DADVXB010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.318"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(<1..411)
                     /locus_tag="KB902_002861"
     CDS             complement(<1..411)
                     /locus_tag="KB902_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6809596.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLDE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNI"
BASE COUNT          121 a          100 c          109 g          143 t
ORIGIN      
        1 tatattggac atggtttggg gcgtgtagtg atgcccatac attttctcaa tcaagtctgc
       61 gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcat ctaacgtgtc
      121 attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcgccattgc ggtcgcgcgg
      181 aatctggaga tgaagttccc catactcggt cttgaccgta cggtcatagg agccgttacg
      241 agaattaccc gtgttaaaac caatgcgatc atacttttcg taatcgagga aagccgttaa
      301 ctccgttttg agaagcgtat tgactgcttt ctccaaatgg acacggaata attcattcaa
      361 atcgcctttg ttcgctagag tctttagaat ttctgtagta aaatcgttca tagggaagtc
      421 ctctcttctg ggctctttgt caataaggac tgatgaagct gtgcaaaatc aaa
//
LOCUS       DADVXB010000308          462 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.319, whole genome shotgun sequence.
ACCESSION   DADVXB010000308 DADVXB010000000
VERSION     DADVXB010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.319"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>462
                     /locus_tag="KB902_002862"
     CDS             <1..>462
                     /locus_tag="KB902_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBB6809597.1"
                     /translation="AEEFIRSRKAYGSRKIKKALSKRGIQISRRKISRIMKNRGLKSS
                     YTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLF
                     NREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDEL"
BASE COUNT          170 a           78 c           89 g          125 t
ORIGIN      
        1 cgctgaagaa tttatccgca gccgaaaggc ctacggctca agaaaaataa aaaaagcctt
       61 atcaaaacga ggcattcaga tcagccgacg aaaaattagt agaatcatga aaaatagagg
      121 attaaaatcg agctatactg ttgcttattt taaagtacat cattctactt gcaatgaagc
      181 caaaacgaca aacgtattga atcgtaaatt cttaagagac aacccattag aagcgatcgt
      241 aacagacttg acttatgtac gagtcgggaa aaaatggaat tatgtctgtt tcattttgga
      301 tctgttcaat cgagaaattc tcggctattc ttgtggagaa cataaagatg ccgttctagt
      361 aaaaaaagca tttagccgta tcaaacaacc tctgacagag gttgagattt ttcatactga
      421 tcgtggaaaa gagtttgata accaagctat tgatgaatta tt
//
LOCUS       DADVXB010000309          457 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.320, whole genome shotgun sequence.
ACCESSION   DADVXB010000309 DADVXB010000000
VERSION     DADVXB010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.320"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            56..250
                     /locus_tag="KB902_002863"
     CDS             56..250
                     /locus_tag="KB902_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809598.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          194 a           61 c           81 g          121 t
ORIGIN      
        1 ttcacttaca tatatttgaa tattaactaa aaacagcaag aaagaagagg atcaaatgta
       61 ttatgtagaa gtaaaaacaa aaggcgtcaa aaacaaacaa tatgtgaaag gtatcagtaa
      121 cgaatatcct ttacttggtt catggaaaga agctgctcct ttttccaaac catgtgccat
      181 aaaaataaag aacgagctag aaaaagaact gacttgtggt aaagctgttg tagatatcat
      241 cgaaaagtaa atccaatgta tagaaaggaa gatcacacat gaaaagcgac gtacaaattg
      301 ctaagattat agaattagaa gaagaagacg cagtgttgac aattgaaaaa aaataaatgt
      361 ttgtatacca tatgattatt tcaatatgta tcctggaatt ggagatctcg tagagctata
      421 tcaagatgaa tcaaatatac ttgtcattca tcatgaa
//
LOCUS       DADVXB010000310          426 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.321, whole genome shotgun sequence.
ACCESSION   DADVXB010000310 DADVXB010000000
VERSION     DADVXB010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.321"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>426
                     /locus_tag="KB902_002864"
     CDS             <1..>426
                     /locus_tag="KB902_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6809599.1"
                     /translation="HNKKISYQYHVGQYLPDWHPWEDYRNFFVSNKKTNGCREIFAIE
                     LPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETGIVGTLSVDVVSRVAKRN
                     LTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVM"
BASE COUNT          148 a           54 c           80 g          144 t
ORIGIN      
        1 gcataataaa aaaatttctt atcaatacca tgtaggacag tatttacccg actggcatcc
       61 ttgggaagat tatcgcaatt tttttgtttc aaacaaaaaa actaatgggt gtagagaaat
      121 attcgctatt gaattacctt ggattataga tacatttggg aaagttaaat cgtttactgt
      181 aatgacccag aaattatcca atcttgatat tgattattcg gacagtttca ctcttattat
      241 tgagcatgaa actggtatag ttggaacttt aagtgtagat gttgtttcaa gagtagctaa
      301 aagaaattta actataattg gtgaaaagat tttaatagaa tgggaaggta acccggattc
      361 tctattttca tggaatgaag aaacttctag tatgacagat attcaattgt acgatgaggt
      421 tatgca
//
LOCUS       DADVXB010000311          397 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.323, whole genome shotgun sequence.
ACCESSION   DADVXB010000311 DADVXB010000000
VERSION     DADVXB010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.323"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>397
                     /locus_tag="KB902_002865"
     CDS             <1..>397
                     /locus_tag="KB902_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBB6809600.1"
                     /translation="RGKQQYQRSIHDRPDNYPDFNSEFGHLEGDTIVGIHHKSAVITL
                     VERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQH
                     DIDIYFADPGTPSQRPLNENSNGILRRNGL"
BASE COUNT          123 a           82 c           71 g          121 t
ORIGIN      
        1 acggggaaaa caacagtatc agcgctcaat ccatgatcga cctgataatt atcctgattt
       61 caattctgag tttggtcacc ttgaaggtga tacgatcgtt ggcattcatc ataaaagtgc
      121 cgtcattact ttagttgaaa gattatctaa agtcattatc acgattaaac ccaacggccg
      181 taaggcatta gatattgaaa ctgcccttaa tcaatggttt tctcgcttcc ctaaaaactt
      241 ctttaaatct attacgtttg actgtggaaa agaattttct aactggaaag ccattagtaa
      301 ccaacatgat attgatatat attttgcgga ccctggaaca ccttctcaac gcccattaaa
      361 cgagaattct aacgggattc tgcgtcgtaa tggactg
//
LOCUS       DADVXB010000312          390 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.325, whole genome shotgun sequence.
ACCESSION   DADVXB010000312 DADVXB010000000
VERSION     DADVXB010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.325"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT          126 a           53 c           56 g          155 t
ORIGIN      
        1 atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa tgtttttaac
       61 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tatattatgc
      121 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      181 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      241 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      301 ccatattttt gaaaaaaagt gagaaaaaag gcttataatt aggatttaga gtaattaatt
      361 agatgtttat tttataggac tgatactata
//
LOCUS       DADVXB010000313          385 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.326, whole genome shotgun sequence.
ACCESSION   DADVXB010000313 DADVXB010000000
VERSION     DADVXB010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.326"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..179
                     /locus_tag="KB902_002866"
     CDS             <1..179
                     /locus_tag="KB902_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6809601.1"
                     /translation="EDSMISGGSLINNSSFMSNITTLGQSYLILISIIVLSVVFASSL
                     MLIKKPKEILSKIS"
     gene            189..>385
                     /locus_tag="KB902_002867"
     CDS             189..>385
                     /locus_tag="KB902_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6809602.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFK"
BASE COUNT          154 a           40 c           65 g          126 t
ORIGIN      
        1 cagaggattc aatgatttcc ggtggaagtt taataaataa tagtagtttt atgtcaaata
       61 taacaacact tggacaaagt tatttaatat taataagtat tattgtttta tcagttgtat
      121 ttgcttcttc attaatgtta atcaagaagc ctaaagaaat cttatcaaaa ataagttagg
      181 agaaaataat ggatatatta gaaataaaga atgtagcata tagttatgca aattctaaag
      241 aaaaagtttt gtcaggagta aatcaaaaat ttgaacttgg gaagttttat gcgatagtag
      301 gaaagtcagg aacaggaaaa tctacacttc tttccttact tgctggactt gataaacctc
      361 aaacaggaaa aatattgttt aagaa
//
LOCUS       DADVXB010000314          381 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.327, whole genome shotgun sequence.
ACCESSION   DADVXB010000314 DADVXB010000000
VERSION     DADVXB010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.327"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(53..277)
                     /locus_tag="KB902_002868"
     CDS             complement(53..277)
                     /locus_tag="KB902_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6809603.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT          106 a           84 c           57 g          134 t
ORIGIN      
        1 aataaaaaaa gagccgttaa caggctcatc gcagtaatag taattttctt tttcatttgt
       61 ttcctccttc ttcgctttca gccgagaaca ttttgtaggt tcgatttgat acacccaaca
      121 cactccctaa aaacgcgcca aaaccagtaa tgatgacaac acagatatct gtgtactgcc
      181 aattgagcgc tttaccaact aaccccacga aagtagctag tgcgggaata attaccagtg
      241 cgaaccattt tagtacttcg aacgttttat tattcatttt cttctctccc taaataaagt
      301 tttaatttgt tgcgtgtgtt ctaccaattt ttctgcatgt gtatctaatc tttcatcgtg
      361 tttctttagt tcttcatgaa t
//
LOCUS       DADVXB010000315          378 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.328, whole genome shotgun sequence.
ACCESSION   DADVXB010000315 DADVXB010000000
VERSION     DADVXB010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.328"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..52
                     /locus_tag="KB902_002869"
     CDS             <1..52
                     /locus_tag="KB902_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6809604.1"
                     /translation="TSTVLKQTKNSDYADK"
     gene            177..>378
                     /locus_tag="KB902_002870"
     CDS             177..>378
                     /locus_tag="KB902_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6809605.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLS"
BASE COUNT          160 a           59 c           50 g          109 t
ORIGIN      
        1 aacatctacc gttttgaaac agactaaaaa cagtgattac gcagataaat aaatacgtta
       61 gattaattcc taccagtgac taatcttatg actttttaaa cagataacta aaattacaaa
      121 caaatcgttt aacttctgta tttatttaca gatgtaatca cttcaggagt gattacatga
      181 acaaaaatat aaaatattct caaaactttt taacgagtga aaaagtactc aaccaaataa
      241 taaaacaatt gaatttaaaa gaaaccgata ccgtttacga aattggaaca ggtaaagggc
      301 atttaacgac gaaactggct aaaataagta aacaggtaac gtctattgaa ttagacagtc
      361 atctattcaa cttatcgt
//
LOCUS       DADVXB010000316          367 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.330, whole genome shotgun sequence.
ACCESSION   DADVXB010000316 DADVXB010000000
VERSION     DADVXB010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.330"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>367
                     /locus_tag="KB902_002871"
     CDS             <1..>367
                     /locus_tag="KB902_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809606.1"
                     /translation="KLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKV
                     NSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISF
                     SPSMMFEKTINSIMLAKLIL"
BASE COUNT          128 a           51 c           55 g          133 t
ORIGIN      
        1 taaattgatg aaaaacatac aatcaatctt tgggatagaa gaagtttttg tcggagataa
       61 atgtatcttt tttgatcaac ctttattatc tgatggttat ggcatagatg aaacagatat
      121 tttcgctaaa gtaaatagta tattttctgg aaaaaaagaa actttaatta agcttcatcc
      181 tagagcaagg acaaatcgtt atggtgaaaa aaacatattg aattccagtt taccgtttga
      241 agtcttgcta cttgaaaatg acttctcttc aacacttttg attagtccta tatctacaat
      301 ttctttttca ccatctatga tgtttgaaaa gacgatcaac tctattatgt tggcaaaatt
      361 aatttta
//
LOCUS       DADVXB010000317          356 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.331, whole genome shotgun sequence.
ACCESSION   DADVXB010000317 DADVXB010000000
VERSION     DADVXB010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.331"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT          118 a           58 c           49 g          131 t
ORIGIN      
        1 aattaagttc atttctatgc gatgaagcat gttttcaaaa tattactctt tcttagatta
       61 aacttcagag tattcaaata gcggaataag gagccttatc ccgcattact gaatgagact
      121 gtgacataag taaaaaggtg acttcaaatt ccttcttcgg aatttgaaat caccttcttt
      181 ataattataa agtatcggtt tcacagcatt cctgaatgat tcctagaatc ttaaacgaat
      241 gattggagtt atcaacattt tttcactcgt ttttagcgaa acaaaaaatg acatttgtca
      301 cagcctcatt aaattattga ttctttttct ttataattga attgtccata tttaaa
//
LOCUS       DADVXB010000318          356 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.332, whole genome shotgun sequence.
ACCESSION   DADVXB010000318 DADVXB010000000
VERSION     DADVXB010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.332"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            76..>356
                     /locus_tag="KB902_002872"
     CDS             76..>356
                     /locus_tag="KB902_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809607.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLS"
BASE COUNT          155 a           52 c           54 g           95 t
ORIGIN      
        1 ttaaatatat aaaaagcctt cgggcttttt cttttaacaa ttaataggaa cgtatattcg
       61 aaaggaatag aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa
      121 cgttatacgg atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat
      181 tcacgccaag cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata
      241 aaacgaaatg aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa
      301 tacaagccaa ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcatt
//
LOCUS       DADVXB010000319          347 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.333, whole genome shotgun sequence.
ACCESSION   DADVXB010000319 DADVXB010000000
VERSION     DADVXB010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.333"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT           82 a           71 c           74 g          120 t
ORIGIN      
        1 gtagctaggt tattctcaac atagctaggt tctagatccc atacataata ttttggattg
       61 tttgagtctc gcatgccgat tcctcggtat ttatattgct caatattcgg ggttcgagtg
      121 tcaccttttt caatcttgag ccagtcaatt cggcatgcgc cggccgtttc tttaggcgac
      181 tgaaaaatgc gaaggtcttt aggcaaaccc ggttcaagtt tcgttggtgt gaatgttaga
      241 gaccatacgt ctgtcaatcc ctcaactggt tttagatctc caaaattaac gttccaataa
      301 ttatatgcta caaaggtttg acttgcgggt tttgttcctt taagcgt
//
LOCUS       DADVXB010000320          342 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.334, whole genome shotgun sequence.
ACCESSION   DADVXB010000320 DADVXB010000000
VERSION     DADVXB010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.334"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            65..340
                     /locus_tag="KB902_002873"
     CDS             65..340
                     /locus_tag="KB902_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809608.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT          154 a           50 c           51 g           87 t
ORIGIN      
        1 ttgttttcat ataaccaaag gcgctatgat ttccatatga aaaaaataaa gtcaggtgaa
       61 aaaaatgaaa cttgaggata aaaaagtcat tttgaagaaa atcaaacgac taccagacca
      121 aatagatggc tatacgatct gttctttcaa aaaagacagg agtataaaag cttatacgca
      181 aaacacagaa aaaggaataa tctatttcct acatgaagaa ggttacgata cccaaacctt
      241 tatgtttact gaaaaaaaag aatttcataa acagatgaaa aaactgattg aaaaagaatt
      301 tccaagaagt cataaactct atgtgaatca gcaattttaa ct
//
LOCUS       DADVXB010000321          338 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.335, whole genome shotgun sequence.
ACCESSION   DADVXB010000321 DADVXB010000000
VERSION     DADVXB010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.335"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(105..266)
                     /locus_tag="KB902_002874"
     CDS             complement(105..266)
                     /locus_tag="KB902_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBB6809609.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
BASE COUNT          113 a           66 c           36 g          123 t
ORIGIN      
        1 caagaaagaa ctatagttaa tatgataaaa attattaaag ttctattttt ctttcttgta
       61 atatatgcta tagcattttt tatcactttc ctaactactc ctctctattt tcttactcca
      121 taactaattg catccactgg acaagcattt ttacatcgtc cacatctgat acactccaga
      181 tgattgcaat tctcaactga atctttattc atttggcaaa cttttttaca ttttccacaa
      241 ttaatacact tatccttatc ctgaatcggc tacactagac tagacagaaa aaataaggtg
      301 tgtagaataa taaaaaacac actggaggat ttttcatg
//
LOCUS       DADVXB010000322          328 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.337, whole genome shotgun sequence.
ACCESSION   DADVXB010000322 DADVXB010000000
VERSION     DADVXB010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.337"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            108..>328
                     /locus_tag="KB902_002875"
     CDS             108..>328
                     /locus_tag="KB902_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809610.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIA"
BASE COUNT          125 a           67 c           48 g           88 t
ORIGIN      
        1 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
       61 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      121 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      181 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      241 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgcg atgggaaaag
      301 aaatttccat catgactgaa atcatcgc
//
LOCUS       DADVXB010000323          319 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.338, whole genome shotgun sequence.
ACCESSION   DADVXB010000323 DADVXB010000000
VERSION     DADVXB010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.338"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT          115 a           34 c           59 g          111 t
ORIGIN      
        1 tataagaagg agtataaaaa tgaacaaaca taatagaaaa ataacgaata acaaagaact
       61 gatcttgtta ctaataggga tttggggtat ctttttactc tttaatatgt atatgccgac
      121 tatgagagcg gatgacgtag tttatgcaag tagattagat gaacttggct atttgggtgc
      181 ttcgatagaa cattataaga catggagttc aagaattatt atagaactat tcttaatgtt
      241 cttttctaaa cactttatgc tatggaaatt attaaattct acgattatgt taggaattgt
      301 agtattactt tgcaagtat
//
LOCUS       DADVXB010000324          315 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.339, whole genome shotgun sequence.
ACCESSION   DADVXB010000324 DADVXB010000000
VERSION     DADVXB010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.339"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            83..280
                     /locus_tag="KB902_002876"
     CDS             83..280
                     /locus_tag="KB902_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBB6809611.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
BASE COUNT          115 a           31 c           68 g          101 t
ORIGIN      
        1 gtttcaagaa ggaattgttt tttgaaattt aatgaatgtt agaataatag tctaaaaaca
       61 ttaatttagg ggtgattaga ttatgaaaca tttaaaaatt ttgtctatta aagagacaca
      121 acttatctat gggggtacca ctcatagtgg aaaatattat ggaaatggag tgtattgcac
      181 taaaaataaa tgtacggtcg attgggccaa ggcaactact tgtattgcag gaatgtctat
      241 aggtggtttt ttaggtggag caattccagg gaagtgctaa aatgaaaaaa atgctaagca
      301 aattgttcat gaatt
//
LOCUS       DADVXB010000325          292 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.340, whole genome shotgun sequence.
ACCESSION   DADVXB010000325 DADVXB010000000
VERSION     DADVXB010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.340"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..185
                     /locus_tag="KB902_002877"
     CDS             <1..185
                     /locus_tag="KB902_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6809612.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           83 a           63 c           69 g           77 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      241 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tc
//
LOCUS       DADVXB010000326          279 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.343, whole genome shotgun sequence.
ACCESSION   DADVXB010000326 DADVXB010000000
VERSION     DADVXB010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.343"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
BASE COUNT           82 a           44 c           48 g          105 t
ORIGIN      
        1 aagaataaat aaaaaagaac tcgcccccct tacattaagc aagtagacaa gtcccttaca
       61 accgactaag attgctagta cattctagca tattgtatgg ggcttctaaa taaaaaacag
      121 ataggaataa ctcctatctg ttttttatcg ttttagaaaa tttgttgggt cgaaatttct
      181 agaagtgact gtttgactgg tttctttttg atgattcttt ggtcgatttc gatttgatgg
      241 atttagttta gcttcgattt tttctttcac ttcttgata
//
LOCUS       DADVXB010000327          262 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.346, whole genome shotgun sequence.
ACCESSION   DADVXB010000327 DADVXB010000000
VERSION     DADVXB010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.346"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(30..>262)
                     /locus_tag="KB902_002878"
     CDS             complement(30..>262)
                     /locus_tag="KB902_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6809613.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           75 a           39 c           46 g          102 t
ORIGIN      
        1 ggactgacct tctgtctcag atttttttgt tatttcactt gaatcaattg attgatcaaa
       61 aaaatcctga ttttcatgtt ctcaaatgat ttaaatccat aagataatcg tttcagtgtc
      121 ttgatatggg gaatcttggc ctctattttg ccattagaat acgggtaaat catagcattg
      181 taaatacctt cttcatacgt taaaaggttt tgaagtttcg tgcgaagttg tgcatcaagt
      241 gtttcaggaa gattttttaa ta
//
LOCUS       DADVXB010000328          256 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.347, whole genome shotgun sequence.
ACCESSION   DADVXB010000328 DADVXB010000000
VERSION     DADVXB010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.347"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            1..256
                     /locus_tag="KB902_002879"
                     /pseudo
     CDS             1..256
                     /locus_tag="KB902_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          101 a           42 c           48 g           65 t
ORIGIN      
        1 ttcagcattt gacaaatggg taaagcaatc taaaacgagt ggttcattca aagaaaaaga
       61 taatcttacg cctgaacaaa aagaattgtt agaactacgt aaaagaaacc agcaattaga
      121 aatggaaaat gatattttaa agcaagcagc gctgatattc ggacgaagag acaagtaatc
      181 gatgcgaata agcatcttta ccctatatca gcgatgtgca gaatattagg tctatcacgt
      241 cagtcctatt attatc
//
LOCUS       DADVXB010000329          253 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.denovo.348, whole genome shotgun sequence.
ACCESSION   DADVXB010000329 DADVXB010000000
VERSION     DADVXB010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.denovo.348"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..>253
                     /locus_tag="KB902_002880"
     CDS             <1..>253
                     /locus_tag="KB902_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6809614.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTP"
BASE COUNT           84 a           51 c           45 g           73 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc ctt
//
LOCUS       DADVXB010000330        19507 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.046, whole genome shotgun sequence.
ACCESSION   DADVXB010000330 DADVXB010000000
VERSION     DADVXB010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.046"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(40..363)
                     /locus_tag="KB902_002881"
     CDS             complement(40..363)
                     /locus_tag="KB902_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6809615.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(350..1057)
                     /locus_tag="KB902_002882"
     CDS             complement(350..1057)
                     /locus_tag="KB902_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6809616.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            1143..1484
                     /locus_tag="KB902_002883"
     CDS             1143..1484
                     /locus_tag="KB902_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBB6809617.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(1666..2502)
                     /locus_tag="KB902_002884"
     CDS             complement(1666..2502)
                     /locus_tag="KB902_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6809618.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KN"
     gene            3100..3963
                     /locus_tag="KB902_002885"
     CDS             3100..3963
                     /locus_tag="KB902_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6809619.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            4063..4545
                     /locus_tag="KB902_002886"
     CDS             4063..4545
                     /locus_tag="KB902_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6809620.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LSESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(4808..5275)
                     /locus_tag="KB902_002887"
     CDS             complement(4808..5275)
                     /locus_tag="KB902_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6809621.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            5398..6249
                     /locus_tag="KB902_002888"
     CDS             5398..6249
                     /locus_tag="KB902_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6809622.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(6500..8458)
                     /locus_tag="KB902_002889"
     CDS             complement(6500..8458)
                     /locus_tag="KB902_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6809623.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSDKA"
     gene            complement(8455..9327)
                     /locus_tag="KB902_002890"
     CDS             complement(8455..9327)
                     /locus_tag="KB902_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6809624.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHTETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(9669..10490)
                     /locus_tag="KB902_002891"
     CDS             complement(9669..10490)
                     /locus_tag="KB902_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6809625.1"
                     /translation="MSRAAKSLHITQPTLSKQLKDLEEELGVTLFTRGSREIQLTDSG
                     RYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAISFISDSLHSLIKAHPDI
                     QFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLPAQDRWGLLIHRNHPLAK
                     QTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVGTYNLLYNASLMVDNGTF
                     GALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSPAARKFLDVLTEKYS"
     gene            10668..11237
                     /locus_tag="KB902_002892"
     CDS             10668..11237
                     /locus_tag="KB902_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6809626.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            11304..12041
                     /locus_tag="KB902_002893"
     CDS             11304..12041
                     /locus_tag="KB902_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6809627.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYSDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            12272..13540
                     /locus_tag="KB902_002894"
     CDS             12272..13540
                     /locus_tag="KB902_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6809628.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            14027..14491
                     /locus_tag="KB902_002895"
     CDS             14027..14491
                     /locus_tag="KB902_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6809629.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            14475..15104
                     /locus_tag="KB902_002896"
     CDS             14475..15104
                     /locus_tag="KB902_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6809630.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEVKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            15458..16936
                     /gene="msr(C)"
                     /locus_tag="KB902_002897"
     CDS             15458..16936
                     /gene="msr(C)"
                     /locus_tag="KB902_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6809631.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            16983..17429
                     /locus_tag="KB902_002898"
     CDS             16983..17429
                     /locus_tag="KB902_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6809632.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(17628..18143)
                     /locus_tag="KB902_002899"
     CDS             complement(17628..18143)
                     /locus_tag="KB902_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6809633.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            18260..19461
                     /locus_tag="KB902_002900"
                     /pseudo
     CDS             18260..19461
                     /locus_tag="KB902_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6174 a         3474 c         4007 g         5852 t
ORIGIN      
        1 tgccttttta tttttctaac ttaattttac aattcgcgtt tataataagc gaatcaacga
       61 aagggaaaga attcctgcca agacgatcac caataagctt tttgaaagaa tagcagctaa
      121 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
      181 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
      241 atactcaagc aacggttgcg gtaaatcgaa ttttttcagt aagacaaatg gtaggaccct
      301 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
      361 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaca atcactaagt
      421 tgcttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
      481 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
      541 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
      601 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
      661 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
      721 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
      781 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
      841 aaacgatgga aagcaatggg ctgtgactag caagcatgct gactgtgata aattgggcag
      901 aaccagcata gaccagcagg gacatcaacg tgacgactag tggatgaaat ccggcagctt
      961 tcccaacgat accaaatgca agtccaatac cgatataacc gaaaacggta ggtaacgtgt
     1021 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
     1081 ataaattttc ataattgtcg ttaaacttgt gaatattcta aatttttaat gagcatttgt
     1141 caatggtggg attgaaacgt aaagaactag cgggtcgcag atttacacgt attgtttcgg
     1201 tgggaggagg cgcgaaaaat cttgcatggc tacaaatcca agctgatatt ttcgatgcaa
     1261 cggtctattg tttaagtgtg gaggaaggac ctgcattagg cgcaacaatg attgctgcac
     1321 tagggttagg gtggttcgac acacctgaaa gttgttgtca gaattttatc caatatacag
     1381 atgcagtgga acctctctta caaaatgtag aaaagtatca taaaatctat caacaatgcc
     1441 ggaaaatcta tccagcaacg aaggaaattt gtcatgactt ataaaacaaa acgcgtacct
     1501 aatagtcaaa tgactaatat tgggtacgcg ttaagtcttc tttacttcat cctttgcatg
     1561 attcgtgttt ttaaagcaag gtctgctgta tttcttgtgg atttaggatg gttgttatcg
     1621 tttacttgct atttttcatt gaaatcgtct ttctttaccg tttctttagt ttttatctat
     1681 ttttttcttt tggttagaaa attctttttc ccgaaagtct tctttcagga tttttatgga
     1741 gtagcgtttt gaataagagg cgtcagtatg atcgacttgg cagacgaacc aagagaacat
     1801 ttgccttttt tctgcatgag gtgcttctgc taataattct ttccataaat aataacagtc
     1861 ctctatcaga agaagggttc gttcatcctc aggctcccaa tagaatgttt cgagagtagc
     1921 aatcacttca ttgatcaatt cgaatgcggg aagataggca ttttgctgaa taagcgattc
     1981 aactgcttct tggatgaact ttcgcatctc catgatgaac ttcgctgttt tcctgttttt
     2041 gtttttcttg ataatatgat cgtatttatg gatgatagtt gttaatttat ctgaataatt
     2101 tattgcatga aatggcatct taactttgaa gcgttcgata aagtgcggat gttctataag
     2161 aatctctgtt aaaagctccc gtacaagaga ggaactagcg gaggaaacaa gggacgagag
     2221 ttcggaaagt gagtagttgg atttttttat tggacgttct tcgtaagcga ataagacagc
     2281 agccatgtgt ttgcattttt ttccttctat ggcatataga caatcacaag tcatgttggt
     2341 cttttcatcc caagtgatca ctaccttata atcttccgtg ccagaaactg ttgcggacaa
     2401 gtacttgctt gtatagttca aatgacggac aaaaccgtgc agatgatagc tgtaaccgcg
     2461 ttccaaaacg ttttcaggaa aatactcaag ccaattattc atctagttct cctttcatga
     2521 aacacttatt tatatttagt ataaagaaac gtttaagaaa aaagtagctg actttacata
     2581 tttgataatc acttttgctc gaattgtcaa aaattcattc tccttttctt ttcttagaga
     2641 atgtgagaaa aagtaaaaga atagcgtgtt ttaaagatgg aacttttttt gttttttatt
     2701 tatctgacaa aaatgaagtg attttgttag aaataaataa ttgttccaat tgataaaaga
     2761 ggtatgatgt atcgcaaaga aaaatccaag cagcgttctg atcagcagtt tgaacaacaa
     2821 tttgctttgt acagtaggta gtaagcggat taactaaggg aataaaagat atttttaccg
     2881 ctttgtttac ttagaatctg tcttccccaa aatttatttt tctaaaggta aaacatagat
     2941 aggcagataa taccaattat ccgttacgaa acgctgcttg agaattttct ttagatccat
     3001 acaacatttt ctacatctga ctaaattggt tcctgattca tcaagtaatt gactttcttt
     3061 gataatatga taaaaaggca agcaaggagg aagataaata tgcttaaaga tctgaaccaa
     3121 ttgatcgatt acatcgaaga acatttgaca gaaggacttt cctataaaat aatagccgaa
     3181 aatacaggaa tctctgaata tcaattaaaa cgcatcttta cgtttattgc agggatgtcg
     3241 ctaatggact atatcaaaaa ccgtagattg gctttggcta atcgcgatct tctagatgga
     3301 tcaagagtga cagaaacggc gtttagatat ggatatgaaa cagtcgaagg tttttcaaga
     3361 gcttttcgtg attggtcagg atatctgcct tcagaaatca gcagatacgg catacaaaaa
     3421 tcttttccac gcttgacatt ttttattgat gtcagaggag gaaaatcgat ggaatttcgt
     3481 atcgaaaaga aagaacagtt ttatgtggca ggtgtggcga aaaaagttcc tgtcaaattt
     3541 gaaggagtca atcaagaaat acaaaagtta gcgcagacga tcacggagac tcaaagggaa
     3601 gagatgcata agttaggaga tttatatcca aatcaagtaa tcaacgtttc ttatggattt
     3661 gatggagacc gcttggaaga aaagggcagt ttgatgcaca tgattggctt tgctacgaca
     3721 aaagaaaatc cgtacgctga tttagaaatg cttgctatag aagaacacac ttgggccatt
     3781 tttcctaata aagggccatt tccccaaact ttacaagata cttgggggaa aatctatgca
     3841 gaatggcttc cttcttcaga ttatgagtta gtcgaagctc ccgagatctc ttttacaaaa
     3901 tggggagagg atttcagtaa tgtttacagt gagatttgga ttgcagtgaa agcaaaaaaa
     3961 tagttaaaaa ataaaaatat ccctagaaaa aagagcgtaa tcgtgtcatt tccctttaat
     4021 tttatgtaag atgaacttaa tataatagaa agggtgggag aaatggcaaa gtataggatc
     4081 gaagaaaaac cagattttac ggtgacgggt attggtgtgg aattgaagag tagcaatacg
     4141 gattttgtcg gtttggctgc agagaaacaa gcatttgagc aaaaagttat cggtaatgga
     4201 acaatagatg cattgaaaca agctgctgaa aatcattatt tctttacagt caacgaaccc
     4261 tataacggga aaatgatgta ctatgtcggt gttcaaacga gtcaggatgt tccaaacact
     4321 acgcgaatca tcccattccc aaaaggaacg tatcttgttg taagcgcttt atcagaatcg
     4381 cctgaagaat taagaaatga tttgacgaat acggcctttg ggcatgtttt aagagaagta
     4441 gaagattacg cctatgttgg gggtccaaat gctgtagtcg aaatgggagt taccaacggg
     4501 aaatatatgg gagaaatctg gataccggta gtcaataaac catgataata tagaggtcgt
     4561 gaaagtagcg ctttgacctg agcattagag aggaaaaatg ggaaatagct ttccatattt
     4621 tgcatttttc agaactaatg ccgagggtca gctacttgaa caccgtttat caagacgtca
     4681 tgacttcagc gctttgacct gagcattaga gaggaaaaag gggcatgaca aggcttttgt
     4741 cccccggaga ataaaagaat ttatgtagac gattccgatc agaaaaatgc aggcacagta
     4801 gagagaatta taaaaatctc tctacgaggc ctgtgttttc tggtcttttt tctttttcca
     4861 aaacggctat tttatgtatc agactatcaa gtgtgatctt agccatttct tcttctgcct
     4921 ttttctgcag ccgagcgtag ctttcttcta aagcttcttg gatattcgca ccaacgacgc
     4981 aatttggatt tgtttttgga tcgacttgga taagctgtgt attaccttcg atgctgcgat
     5041 agacatctag taaagaaatc tgatctggac ttttggcaag ggaaggctgc ggttttccgg
     5101 tttttgtaaa gatcaaaccg gattttttga gctgactcat gattttacgt acatttgctg
     5161 catttgtttc gatactactg gcaatcatct cactagaaag tgatcgggta tcttgaaaca
     5221 tttcaatata ggcaagtaca tggattgcat cactaaattg cagagaatac ttcatcagtt
     5281 gtcatccttt catttttttt gcttgactta tcttaccaca ctctttatga taaaggtgta
     5341 atttataaat gtacagctgt aaatcttaac aaataaaaag aatagggagt ggcaaatatg
     5401 cattatttag taacaggagc aactggaggt tttggtggtt atgcgctgga attcttaaaa
     5461 aagatggttc cacaaaatga aatctatgta ctagtacgta gtgaagaaaa aggagaagca
     5521 ctgaaagaag ctggatttaa tatacgtatt ggtgattatg atgatttaga ctcaatgaaa
     5581 gaagcgttga aaggaataga tcgattgctt tttgtctctg gcgttccagg aaatcgtcaa
     5641 gccgaacata agaatgtagt gaaggcagca caagcagctg gggtatctta tatcgcttat
     5701 acaagttttg cagatgccga tcactcgatc agtgtattag cgccagatca ccaattcact
     5761 gaaaaaatga ttaaggattc aggtatttcc catacatttt tacggaataa ttggtatgta
     5821 gagaatgaat tacctatcat tgggcaggct ttaaaaactg gtcaattcgt ttatgctgca
     5881 ggaaatggaa aaacaggttg ggcattgaaa cgtgaatatg cagaagctgc agcaaaagta
     5941 ctagtagaaa gtgactctcc agaaatctta gaattatccg gcaatctaac tgactatgaa
     6001 gaattagcca aggcattaga gcgtgcgaca ggtaaagagt tagaaattat tgaagcaagt
     6061 gatgcagcgt ttgtcgaaaa tctaaaagaa gccggattcc ctcaagaagc agctgacatg
     6121 tttttagcga tccaacatga tattaaaaag gatcagttag ctatttcctc tgatgattta
     6181 gaaaaagtat tgggaaaacc attaacttct cttgaagcag cattaaaaga aatattggat
     6241 caggaataat gtataaagag gttgtgaaaa agccgattag ttttgagtat gaagaaaaat
     6301 tttgtgaaaa agctgttctg catcaagtaa taagaagagt caaataaaaa atagctcttc
     6361 atatgtttcg tttggctgga cttattaccg cggagttggc aggagaacgc cgtttttatt
     6421 cggaaaaagg agctgagaca agatttttgt ctcagctcct gtttgtttat cgataaaaaa
     6481 gtctggggaa gacgatggct caggctttgt cggaaacaga gccgatttta tcatttgctt
     6541 ttacatcacg tgcgggttcg atttctaagc tttggacttt gtcgccattt gtgaatacaa
     6601 cgaccatatc cgtgtttttg cctgcagatt gaatagcggc aagatcaact aaagcaatca
     6661 attgacctct tgcgactttt tgaccttctt ctacatataa agtgaatggt tcgcctttta
     6721 agtcaacagt gttgatgccc atatgaagca agacttcgat accagcatct gtttggattc
     6781 cgacagcatg tttcgttggg aaaatgtttg tgatcgtacc agcgattgga gagaagattt
     6841 ctccattttc tggtaataca gcatagccgt cacccatcat tttttccgcg aatacatcat
     6901 ctgaaacttc agtgattgga atcagtttcc catttgcgat agcgtaaata tcttgttcga
     6961 tcgtttcacc ggcaaatgtt tctgttttaa ccacggtgtt tgtttgtgca ggtcgtgctg
     7021 cagcaccacc atgtagtttt gccatctcat ctgcaacgaa ttgtacttct gtacctacga
     7081 tgacttgcgc attttttccg tcgatgatct tcataccagg tacgccagtg gctttgattt
     7141 tattttgatc gatcaggcct gtatctttga cttgcaaacg aaggcgtgta gtacagttat
     7201 cgatcgaagt tacattgtcg gctccgccta atgcagcgta gattttgctt gcttgtgccg
     7261 catatttatt gtctgaatta gtcgttgcag tatcgtcatc tgaaagatct gcttcctcgc
     7321 ggccaggagt catcagatgg aattttttga tagcaaagtt aaagccaaag tagtaaatca
     7381 ctgctgttac taatccttgg acgatcaaca tcaatggctg attcgcaatc ggatttttca
     7441 aagataggaa gtaatcgaca aatccggcac taaaggcaaa tcctgctgtc caatggaaga
     7501 atgcactcac tgctaaagaa atcccagtga aaattgcatg caagacatat aatggccaag
     7561 caacgaacat aaatgaaaat tcaagtggtt ctgtcacacc agtaaagaat gaagcaaaag
     7621 ctgctgctag catcaaggaa gctgtttttg ctttgttttc tggacgtgca tttctgtaaa
     7681 tagcatatgc tcctgctgga agcccgaaca tcatgattgg gaaaaatcca gcttgataca
     7741 ttcctgttac gccttttgtt ccttcagaag ccaaaaattt accaatatca ttgattcctg
     7801 ctacgtcaaa ccagaacacg gagttcattg cttgatgcaa tcctgtaggg atcagtaaac
     7861 ggttgaagaa gccataaaga cctgcaccac cccagcctaa actcaaaatg aatttagcaa
     7921 aagaaactaa agcagagtaa accggaggcc atacgagcag tagcactgca ctgatcagca
     7981 acatgacaaa ggcagccaag attggcacta gacgcttgcc gctaaagaaa gataaagcca
     8041 tcggtaattt tgcttcgtgg aaacgattat aaagagctgc cgcaatcaat ccggcaataa
     8101 taccaataaa tacgttactg atctgagcaa aagatggatc aactgattct ggtttgatat
     8161 tcaataaagt agctactgaa tcagttttta aaacatttac tggaacttca aatgcgacca
     8221 aacctgccaa ggcagcagca cctgatttgt ccactgacat ccctagtgct aacccaacgg
     8281 caaacagcaa aggtaattga cctaaaactg cgttaccgcc agcttgtaaa aaatgagcga
     8341 caatgtcgtt actataagat gcccaccagt ttccgatccc tactagtaaa gcagcagcag
     8401 gtaagaccgc aactggaagt tgaagggaac gtcccattcg ttgtagatat gctttcaatt
     8461 tttttcctcc tcatgattgt taacatttgt ttgtacgatt gcgcttctta aacgctcgat
     8521 atggatggcc aagtaaccca gttcttcttt cgtgatcgcg agctggtatt ctttggtcag
     8581 caacacacgg atttttttag aaatcttata gctttctggg tattttcgtt tgaccatttc
     8641 tacgatttcc gtgtctaaaa cagcatattg ttgcgcatgg gttcgttgta gaagcagtcg
     8701 taaatgattc accagtcttg aataattcag tgaaaatggt tctgaatgga tatctgtttc
     8761 caattctgat tccactaaat ggatgatgtc agatacaatc gtcacttcac ggatactgcg
     8821 atggttattg ttccgaccgc ttcgtccgct gtgaatatgg attgcgatat atcctgcttc
     8881 gtcataagta tatggaatcc caagctcttt tgtcagatac tctactgccc attgagcaat
     8941 actgaattca tcactgtaaa gcacttcgat ttctcttaaa agtttgttgc ggatgacgat
     9001 accgttatta atgttctccg cagaaaaagc aatgtggtcg gtcaaagcga tcaatacatg
     9061 ttcattcaac ttttccatca aaacagtttc cgtatgatca atgatcgttt ctgctgcaaa
     9121 taaaaagcgt tcatcaatct gattaagtaa attttgcaac ttgatttgac cttctggttc
     9181 catgacaaat atccgttcga catcacgatc aaaaatcaaa tcatttcttt ttctgtcaaa
     9241 tccaatccct tttccaatag ctactttttc ctgtccaccg tcatctacca atactgcatt
     9301 ttgattaaag atctttttga ttttcatgcg cgcacccttt ttgaagattt ggttttcacg
     9361 tttgctagac cagttgattg cggccaaaca aaaatagaca cgaaaaacct cctagggaaa
     9421 ccatgttcct cagagatttt tcatgcctag tatgatctag tcacatgaaa cgaattattg
     9481 ttaacgtaat caattttata tagacagtta tgttttgtca attctttttt tataattata
     9541 gtaatttact ggaattatca gaaataaaag gaagaaataa attaagaaac ttatgttatt
     9601 taatcgttgg atcttttgct tatcttattc gttgttaaaa agctgaaagc gaaggaaaaa
     9661 aactctactt aactgtattt ctccgttagg acatctaaaa atttacgagc agcaggagaa
     9721 agaggctggt cttttttcca aatgagattc agtgaagctt gtaatggcgg atcgagtggg
     9781 atgaatattt tttccgtccc ataagtattg atgatcccat ctagagctaa tgcaccaaaa
     9841 gtcccgttat cgaccatcaa agaagcattg tacaataagt tatatgttcc gacgatcgat
     9901 aactgatcta tgctgaaacc tagccattca gctagttgac tgtccactga cgtttgccgg
     9961 gaaatgatca aaggaacagt tttcagttcc tgcggatgga tgacggtttg ctttgctaaa
    10021 ggatgatttc gatgtatcaa aagtccccaa cgatcttggg ctggcagtcg aaatgactgg
    10081 tatttttgtt tgtttgtcgg ttcgattacg agtccaaaat caagtaatcc gctatccagt
    10141 ttgtctatga tatcatctgc attcccgcta tataaatgaa actggatatc aggatgcgcc
    10201 ttgatcaacg aatgaaggct atcagaaatg aaagagattg ctttagtttc gcctccgcca
    10261 atgtagattt ctccagagat gattgcgtca tttgttaaat tgttcgccgt tttttctacc
    10321 aacgacaaga tttcttttcc ttttgaataa agatatcgac cagaatccgt caactgtatc
    10381 tctcgggagc cccgagtgaa aagtgtcaca ccaagttctt cttctaaatc tttcagttgt
    10441 tttgagagag taggttgcgt gatatgcaga gattttgctg ctcggctgat attttttttt
    10501 ctagctactg ctaaaaatac gtcagtatac gaatatccat tttttccctc ctgtttttaa
    10561 aaaagcatac cactaagtat agttaaaagg aatagttaag tatgttttat aagtattaga
    10621 catgataagc cgtccgttat aaagtaagga taaaaggagg gagcaaaatg acaagcctca
    10681 tcgaaaaaca aatcgtcaat aaagagattc gagtaacgga tccgctcttt gaagtgatcc
    10741 atcagatcca agctgaaaac gaagagcctt tagcagcgct gaatactggg taccatgaac
    10801 cagcagatat ccgcaaacgg ctagaaaata tcattagtga caaagtagat gatacggtga
    10861 ctgttctgct gcctttttat acagatttcg gcaaacatat tagtataggg aaaaatgtct
    10921 ttatcaatcg tcaagtgatg ttcgttgact taggtggcat ctgtttagaa gattcagtat
    10981 tgattggtcc tcgtgtcaac ctcatcacgg tgaaccatct aaccgatcca aaagaacgaa
    11041 gaggcttgtc agtaaagcca atccacatca agaaaaatgc ttggatcgga gcaggagcaa
    11101 ctattctgcc aggcgtaacg attggcgaga atgccattgt tgcagcgaat gcaactgtta
    11161 cgaaagatgt cccagacaat accatcgttg caggaatccc tgccaaaatc gtcaaacctg
    11221 tcgaacggat tatttgaaca gtaagatgaa ataagagata gtgagtataa gcaagagatt
    11281 tttcaaaaca ggaggagaat agaatgaatg atttatcaga aaaagtgatt gtcatcatgg
    11341 gcgcttcaag cggaatcggt gaagcaacaa cgaagctatt agcagaaaaa ggggctaaac
    11401 tagttatagc tgcacgccga gaagatcgcc taaaagcaat aaaagaatct ttaccagaag
    11461 ctgagctata tattcaaaca gcagatgtaa gagattttgc acaagtccaa gcagttatcg
    11521 atttagcgat ggaaaagttc ggtcgaatcg atgtattgta caataatgca ggaatcatgc
    11581 caaccgctcc attagttgaa ggtcaccgtg atgaatggca aaatatgctt gatatcaaca
    11641 tcatgggtgt gttaaatgga atttccgccg tacttccaat catggaaaaa caaaaatctg
    11701 ggcatatcat ttcaactgat tctgtggcgg gacatgttgt ttattctgat tccgccgttt
    11761 attgcggaac aaaatttgct gtccgtgcaa tcatggaagg attacgtcaa gagcaacggc
    11821 aaaataacat caaatctacg atcatctctc caggagctgt tcaaactgaa ttatatcaaa
    11881 ccatcagcga caaaaaggct gctcttgaac ttcatgaagc gcaaaaagaa tggggattga
    11941 cctccgaaga tatagcttct gctgtagcat ttgcgataga aacgccagac cggatgtctg
    12001 tcagtaacat gattatccgt ccgacgacac aggaagtata atccataacg gataatatcc
    12061 aaagagaatt acttgttaaa tagttattca aacgaccatc aatttaaggc gtgaatggag
    12121 aagaatattc ttcatttacg tctttttatg tagaaaaagc aaatttatca aaaagaaaca
    12181 aatgttattt aaatatggac attgacttgc ttttactttt ttagttacac tgttatttag
    12241 gaaaagtttc ataattcaaa ggagaaaaaa gatgaaagca aagaatttat tatttagcgt
    12301 tattctttta ggaaatctag cagttgccaa cacaacagtg ctagctgaag aatcgacaga
    12361 aactgtcgca actcagacat cgagttcttc agaaacagga attgaaaacg atacagagag
    12421 tactttgcag tcagctactg tctcagaaaa tacaatttca accgaagaac caacaactga
    12481 aacaacagaa caaacacaaa ccgaagacag tacatcagca gaagctcaga acaatccaga
    12541 gaatgcagaa gaaatcacga accaattgac agatgggcaa acattgacac atacccatca
    12601 agcagatttg tctgaattcg aaaactatac tggctatgct ttttatgctc gctcatctgc
    12661 taattctcaa caagcgttca ttgatagtat tgcctcaact gcacaaagtt tggcaagtgc
    12721 caatgactta tatgcatcag tcatgattgc tcaagccatc gttgaaagtg gctgggggaa
    12781 cagtactttg gcttctgccc ctaattacaa tctatttggg attaaaggaa gctataatgg
    12841 ccaatctgtt acgatgccta cttcggaata tgtgaatggg caatggatta cggtgaatgc
    12901 cgcttttaga aaatatcctt cgtacaaaga atcattgcaa gataacgtaa cggtattgaa
    12961 gacgacttct tttcagccag gcgtttacta ctattccggt gcatggaaaa gcaatacgaa
    13021 ctcttacaaa gatgctacgg cttggctaac aggtcgttat gccactgcgc ctaattatgg
    13081 ttctacattg aacaatgtaa tcgaaaccta taatctgaca cagtatgata cagcaccaac
    13141 ttcaacttct ccgatgtatc gtctgtataa ccgtcataca ggagaacatt tatatacatt
    13201 gaatgccgga gaaaaaaatt atctgccaac tgtaggctgg gaatatgaag ggattgcttg
    13261 gcaagcacca aacagcggac aacctgtcta ccgtttatac aatccttaca gtggagacca
    13321 tcattacaca atggcacaat ctgagatcaa ctctttaaca aaaatcggtt ggcgttatga
    13381 aggtctaagt ttttattctg gtggttccaa gccaatttat cgactattta atccaaatga
    13441 aaaaactggt acccatcact ataccttgag tgctaaggaa agagattggc taacaccgat
    13501 gggctggaga tatgaaggaa taggatttta tggttattaa aaagaggtag tgaaaaagct
    13561 gccctgcatc aagtagtaag aacagccaaa caaaaacaga ttttcatgtt ttttgtttgg
    13621 ttgaacttat taccgcagat gcaagttttt gaacaccgtt tactcaaaaa aggttgtgac
    13681 aacatcttgt cataactttt ttattactgt ttaagcatac tgatccaatt tctaatattc
    13741 gacgggattc ttgcaaaagg cgatttcgga aatttttggc ggtgtaaaat tttctactgc
    13801 agaagagcta tcttctatag tttgataaga atcaataatc ttggttttag cgttgtgctt
    13861 tctttatcat tttttccgtt cattctacaa aaaatttctt ttctctatac ttttctattg
    13921 agagcgtttt ttttattaca cagctgattc tttgactttt ttcttttttt attctattat
    13981 tgacaagtca atcgttgacg agtcaattat tagaaaggag gaaattatgt ctttagaaga
    14041 gattagtcac cttttatatc aaatcaaatt agccgatcaa aaaatcgtcc agatctttga
    14101 agaaaatatc ggtataagtc ttactagata cgagatcatg atgagactga aagaagaaaa
    14161 tccattgcta caaagcagtt tgcaagaaaa gttgcagatt gatcaaggag cagttactcg
    14221 tcatctgaag gtattggaag caaatggcta tgtttcgcgt cagagaaatc ctcagaacaa
    14281 ccgggaagtg tatgtagcgc taacagaaaa agcccagaag aaaatcgagc attgtgaaat
    14341 ggaccataaa gatacaggtt ccgtgctatc cccggctttc agcgatgtag aaatgaaaca
    14401 atttctaaca cttttagata aattgaatac ccaactttgc aatataacaa cagaaacgaa
    14461 agaggttaat aataatggaa caaaaaaatg atttttcaac aattatgact ggtagaagat
    14521 ccgttcgcgt atatgatgaa acatacaaaa tcccacacga agaaatgctg gaaatgatca
    14581 aagaagcgac gactgcacct tcttctgtca atatgcaacc atggcgcttt gtggtcgctg
    14641 aaagcgagga agtaaaagaa atcttgcgtc ctttgatccg tttcaatacg agacaaaatg
    14701 atacttcttc tgcaatggtc atgatttttg gcgatatgca atgttacgaa tatggcgaag
    14761 aaatctataa ccaagcttac gaatcaggga agatgccaaa agaagtcaga gatcaacaat
    14821 tagctgcgat cattccttat tacaagagtt tttcaagaga agaaatgaac gatgtagtca
    14881 aagtcgattc tagcttagcg gctatgcaat tcatgttagt tgcgcgtgat catggctatg
    14941 aaacaaatcc aattggtgga ttcgaagcag atcagttggc agaggcattt ggtttggata
    15001 aagaccgtta tgttccagtt attattttat caataggaaa agcggtagaa gaaggttacg
    15061 agtctgttcg tttagcacca gaaaagatca ctacgttcga ataaaaggtt ttcagttact
    15121 attcagtagc tattgctttt tttgaatcgt gtgtggtaac ctaataaaaa aggaggtcgg
    15181 aaaaatgact gcatcgatga aattacgttt cgaacttttg aataacaact aaataaattc
    15241 aaaagacatg tataaacaac aatttcatgg atggagtatg tccatttttt cgaacgacag
    15301 tagaataggt gaaagctatg acagatttgg tgatttagtc atagttattt cgttcagagt
    15361 aggaaaagat gtgatgcagt ttttttgcaa acagattttt ctgctctttt ttagtatcga
    15421 taattgttgt tttacatgaa ataggagtgt aaaacatatg gaaaatttag cagtaaatat
    15481 aacaaatcta caagtcagct ttggcaacca gctagaacta tctattgatt ctcttcgtgt
    15541 ctatcagcaa gatcgtatag ggatcatagg agaaaatggt gtcggtaaat cgactttgct
    15601 caaactaata gccggtgaac tttttcccga tcatgggaaa atccaaacag agatcacctt
    15661 caactacctg cctcaattaa cctatctcgc tgaagcaaag gacctaaatt tggaattagc
    15721 cagtcatttc cagttaagac tggaagaaac ttcagagcgg aaatggagcg gaggggaaga
    15781 acgaaagatc gagttgatac gtcttctttc ttcttatgaa caagggatgc ttctagacga
    15841 gccaacaacc catctagata gaaaaagtat tgatcgactg attgaagagc ttcgttatta
    15901 ttatggtacg ctggtttttg ttagtcatga tcgctatttt ctagatgagc tagcatcgaa
    15961 aatctgggaa gtaaaagacg gagaaatccg agagttttcg gggaattata gtgcctatct
    16021 cactcaaaag gaattggaga aaaagactca gctacgagaa gcagagtcga tcatgaaaga
    16081 gaaaaaacga ttggaaaaat cgatccaaga aaagaaaaaa caagcggaaa agttggaaaa
    16141 agtgtccagt aaaaagaaaa agcaacaaat cagaccggat cggttgtctt cctctaaaca
    16201 aaaagacagt gtacaaaaag ccatccaaaa gaatgcgaaa acattagaga gaagactcca
    16261 aaaaatagga gaaacaacca agccgcagca gatgaaacaa atccgttttc cagtaccaaa
    16321 atctcttgaa ctccacagcc gctatcccat catgggacaa aatgtccaat tggaaagaag
    16381 tgggagaaca ttactggtaa atggtgattt tcagttttct ttaggtaaaa aaatcgcgat
    16441 tgtcggtgaa aatggttcag gtaagacaac cttattagaa catatccgca aacaaggaga
    16501 aggaatcctt ctctctccga aagtaagctt tcaagtatat cagcaaaagg gttatcaaat
    16561 gacatctgaa gaatccatca ttcgttttgt catgagacaa acagagtttt cagaatcgct
    16621 tgtccgtagt ttgctgaatc acttagggtt tgctcaggaa actttgacga aaccgttatg
    16681 tacattaagt gggggagaag cgacccgtct gacgattgct ttgcttttta ctaagccaag
    16741 taatgtgttg ctgttagatg aaccgactaa ttttattgat atggcaacga tcgaagcttt
    16801 agagaagcta atgcaaatat atccgggaac gattttgttt acttctcatg attcttactt
    16861 tgtcgagcgt acggctgatg aagtttatga aataaaaggg cagaaaataa aaaaagtact
    16921 tacgagaaat ttttaaatgt gctacgatga ttttcgtgac aaatttaaag gagtggtaca
    16981 gattgcctac aaataaaaaa gaaggaataa tttttacaac aatgatgtgt tttttgatgg
    17041 tcttggggat gagcgcgtat aatttatggc tgcatcaaga tcttcattta tcaagtttgt
    17101 tgattggtct agtgcctgga ttcgtggtgg ctttcatttt ggatgtcttc atcatcggtg
    17161 tgctggcgaa aaaaattgcc tttaaactac cagtaaatcc agaaagcaag gtccaaatga
    17221 tcttaactat ttcatgcttg atggttttag gaatggtgac atgtatgtct ttattcggtg
    17281 tgatcatgga acaaggaata cctgatcaat tattctctgc ttatatgaat gcttggaaaa
    17341 tgaatgtgat tgccgcttta ccgttgcagt tgatcatcgt tggcccgctt tcaagaagtg
    17401 tgctaaaagc aattcaaagt aatgaatgat ggaacactgt tatttgaaaa aaggccttgg
    17461 catgcttttt gtcatagtct cttgaatgca gttctagaaa aatagtgatc cgaacgatag
    17521 gttttggcct gtcgttcgga tcgctttttc ttttccaact gtattgctct tttattgaag
    17581 ataatttgct cttcaataga tatttctaga aaggttctgt ttatccctta ctcaaaaaac
    17641 tgctgcattt gttctcttac ttgctgacac cattggagtt cctgctgaca aagcataatt
    17701 ctgcgctgga tcacaacata acgtccaaat tcttgtttct tgtctagcga gaggtcattc
    17761 aatttttttt gatttttttg catgattttg ttcagctgtt gttctctagt gaatagcagt
    17821 ccagtagctg ttgttttatc gagcgtcgaa aaagcataga tttttgctag aaattcatct
    17881 ttttgcgtag gagcgggagt ttcctctttg atccattcct ctacaagagc acgtccttca
    17941 tcagtcaagt ggtagatctt tttttgagag tgctcgtctt tgtccaaaac ggtcacataa
    18001 ccctgctggt ctaacttggc aagcgttgta tagatctgac tgtgatgggc ttcccaaaaa
    18061 attgtgatca gctgcttcaa ttcataccca gaacgtggtt tggataaaag cacgcataat
    18121 aatatatagg ctaaagtatt cataaaaatc ctacctctcg tcttattttc tttattatat
    18181 cacagtaaag tttccacgtt ttacatgtgc atatttacat gtaaaataaa tcatgtatga
    18241 tgctaataga gagaaaggga tggaaatatt ggagaatcaa atagatatac aagaacaaac
    18301 aaatgaagaa acaaagggga aaagttcagc gctagttgta gcagctacct gtatgatcgc
    18361 ttttatggga gtgggtctag tagacccaat cttaaaaacg attgctgcac agttaaacgc
    18421 tacgccagct gaaacgaccc tgttatttac tagttacatg ttagtcactg gtgtggtgat
    18481 gctatttaca ggtttcttat ctagtcggat cggtttgaaa aaacattgat gacaggattg
    18541 tttatcatcg ttgtattcgc tggtcttggc ggattatctg ggaatatcgg aatgctgatt
    18601 gggttacgtg ccggctgggg tgtcgggaat gctttatttg tctctactgc tttagcaacg
    18661 atcgtcagta ttttagttgg taacacagaa aaagcaatca tgatgtatga agcagcactt
    18721 ggctgcggaa tggctgttgg ccctctagtc ggtggggtct tgggcagtgg ttcatggcgt
    18781 tatccatttt ttggggtagc atttttgatg ttttgcggtt ttatagccct agcggtactt
    18841 ttacctgaaa ctgagaaacc aaagagaaaa gtaggccttt gggaaggtgt caaagcgtta
    18901 agcaatcata aacttcgttc agttggacta atcgcattgt tatataattt cggattcttt
    18961 actttacttg cgtatgcgcc atttttattg attggctatt ctgaattaga agtcggtttt
    19021 gtattttttg gctggggtgt gcttctggct attgcttcga ttttcgttgc accggctctt
    19081 gagcggaagt ttacgactta tcggacaatt ttagcagcat ttgtcttatt cattatttgt
    19141 ttgctgttat taggagctgg aacttctatg ccagtccttg taccgatcag cattgtgtta
    19201 gcaggatttt tccaaggaat tatcaataca ctgttgacga cgattgctat ggaaatacca
    19261 ggtctgcaac gaaacgttgc ttcgtccagc tatagttttg tccgcttttt cggtggagct
    19321 ttagcaccat ttattgcagg tgtgattggt gaacatattg gtgaaagcta tgcgttttat
    19381 tttgcaggtg ccattgttct tatcagtgta tgttgtatca tttatcaccg taattatttt
    19441 gctacaaatg aagaagaata agaaatcaga ggttgtgaaa aagctgtcct gcatcaagtc
    19501 ataagaa
//
LOCUS       DADVXB010000331        12713 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.080, whole genome shotgun sequence.
ACCESSION   DADVXB010000331 DADVXB010000000
VERSION     DADVXB010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.080"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(134..577)
                     /locus_tag="KB902_002901"
     CDS             complement(134..577)
                     /locus_tag="KB902_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6809634.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="KB902_002902"
     CDS             complement(795..2135)
                     /locus_tag="KB902_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6809635.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTFW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="KB902_002903"
     CDS             2404..3300
                     /locus_tag="KB902_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6809636.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="KB902_002904"
     CDS             complement(3450..4391)
                     /locus_tag="KB902_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6809637.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHADLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="KB902_002905"
     CDS             4517..5638
                     /locus_tag="KB902_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6809638.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB902_002906"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB902_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6809639.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="KB902_002907"
     CDS             7426..7992
                     /locus_tag="KB902_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6809640.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="KB902_002908"
     CDS             8203..9264
                     /locus_tag="KB902_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6809641.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="KB902_002909"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="KB902_002909"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6809642.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="KB902_002910"
     CDS             10177..12159
                     /locus_tag="KB902_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6809643.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB902_002911"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB902_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6809644.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         4187 a         2328 c         2633 g         3565 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 caaaatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 taatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccgcgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt ttt
//
LOCUS       DADVXB010000332         9102 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.116, whole genome shotgun sequence.
ACCESSION   DADVXB010000332 DADVXB010000000
VERSION     DADVXB010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.116"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..1271
                     /locus_tag="KB902_002912"
     CDS             <1..1271
                     /locus_tag="KB902_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6809645.1"
                     /translation="FHMVLIKSMNYSGLVFIFLGIELTQVFSPVWGDGLYPNGLLLAI
                     IVLISVMLFVIRFISISLFYVFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPF
                     SINNMMFYQRSLLLFLTAGVILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEV
                     LRKEIKEIDRNTKEFLATEAVIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERD
                     GLDESYRSGKLSSNGYRFYSRFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMF
                     WQRRYADRQTFISDEDIQEIRETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEG
                     IKMNSGNLISSWMIQQDSLFTKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINL
                     LESYTMNKPSDNFSFRFAFRAKSKKTSPIK"
     gene            1431..3317
                     /locus_tag="KB902_002913"
     CDS             1431..3317
                     /locus_tag="KB902_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6809646.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            3329..4276
                     /locus_tag="KB902_002914"
     CDS             3329..4276
                     /locus_tag="KB902_002914"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6809647.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            4296..4823
                     /locus_tag="KB902_002915"
     CDS             4296..4823
                     /locus_tag="KB902_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6809648.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4886..5539)
                     /locus_tag="KB902_002916"
     CDS             complement(4886..5539)
                     /locus_tag="KB902_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6809649.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKLERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            5671..6513
                     /locus_tag="KB902_002917"
     CDS             5671..6513
                     /locus_tag="KB902_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6809650.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            6671..7567
                     /locus_tag="KB902_002918"
     CDS             6671..7567
                     /locus_tag="KB902_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6809651.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            7570..8283
                     /locus_tag="KB902_002919"
     CDS             7570..8283
                     /locus_tag="KB902_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6809652.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            8303..8821
                     /gene="msrA"
                     /locus_tag="KB902_002920"
     CDS             8303..8821
                     /gene="msrA"
                     /locus_tag="KB902_002920"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6809653.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            8818..9045
                     /locus_tag="KB902_002921"
     CDS             8818..9045
                     /locus_tag="KB902_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6809654.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
BASE COUNT         3238 a         1553 c         1854 g         2457 t
ORIGIN      
        1 agtttcacat ggttttaatt aaaagtatga attattcagg attagtattt atatttttag
       61 gaatcgaatt gacgcaagtg ttctcgccag tatggggaga cggtttatat ccaaacggtc
      121 ttttattagc gattatcgta ttaatctctg tcatgctttt tgtgatcaga ttcatttcta
      181 tcagtctttt ttatgtattc aaagatggca gtaaaaagtt caaaaaacag ttgaacgaga
      241 tcttgatctt aacatttggc ggtgtaaagg gaacagtcag tttggctacg atttttattt
      301 tgccattttc aatcaataat atgatgtttt accagcggtc tttgcttttg tttctgacgg
      361 cgggtgtcat cttagtgact ttggtcatag ggatcattgt cttgcctatg ctgacggaaa
      421 cagaggaagc gaaaagcacg gatttgaatg ctttgatgat tttagaagag gtcgttgaag
      481 ttttgcgaaa agaaataaag gaaattgatc gtaatacaaa agaattttta gccactgaag
      541 cagtgataga aaattatcaa gaacggatac gtgatctgta cttggaagat ttaaccgatg
      601 atgaaaagca agaagtacaa gaaatacaag cactgatttt gtcgatcgaa cgggatggat
      661 tggatgaaag ttatcgttcg ggcaagcttt cttctaatgg ttatcgtttt tactcccgtt
      721 ttctttctcg attcgaacat tctatcacaa gccagatttt gtcttttatc ggcttttggt
      781 tcattgttgt ccgtaggtta atgcgaatcg ttctccatcc gaaaatgttt tggcaaagaa
      841 gatatgctga tcgtcagaca tttattagtg atgaagatat ccaagaaatc agagagacat
      901 atcaaaaaaa tactcagttg attattgaaa gtttagataa cttgactgat atttatgatg
      961 aaacgatggt tcaatttttt atccagcaac gcaaacttga aggaataaaa atgaactcgg
     1021 ggaatttgat ttcttcgtgg atgatccagc aagatagtct gtttacgaaa aaaatgctaa
     1081 gaggttatta tcttgaaaga aaaatcattg atgaatacga agttgctgaa aaaatcacga
     1141 cgttttctgc gaacagctat cgcaggaata tcaatttgtt agaatcttat acgatgaaca
     1201 aaccatctga taacttttct ttccgatttg cgtttcgagc aaagtcaaaa aaaacgagtc
     1261 caataaaata aaaaggtaaa aattttcaag ttttataaaa aacaaaacat atcagaacag
     1321 gatcgaatcg gtcctgttct ttttttgaga acacaaaaag aacaaatacc aaaaaaattt
     1381 tcctgaagtt cactattttt atgatacaat atccaagata aggagggaac atgttgaaag
     1441 aattaaaagt aactgacctc aaaaaaactt atggtgaaaa agatttgttt gaccagattt
     1501 cttttttggt ccacgaaaaa gaccgtatcg ggttgattgg gacgaacggg acgggtaaaa
     1561 caagtctctt aaatattatt gccggtatcg atagcagcga cggtgatcgg caaacagtgt
     1621 tttatccaac tgattaccgt attggttatc tttctcaagc agctgaattt tccgatgaat
     1681 taactgttct ccaagcagtc tttcaaggaa acagcccctt gatccaaact gttcgagcat
     1741 atgaggaagc attgatcgaa ctaggggaaa acggagaaga ccctgatgtg caaaaacgtt
     1801 atgctaaagc agaagaacaa atgaataaag aagatgcttg gactacagat accaacgcaa
     1861 agattatttt gcaaaaatta ggaatcagtg aattagataa aaaaatcagt actttatcag
     1921 gtggtcagaa aaaacgagtt agtctggcgc aagtgttgat tgatgaaccc gatttactat
     1981 tactagacga accaacaaac catttagatt atgaagcgat cgagtggttg gaaaactatt
     2041 tgaaacaata ccgtggcgca ctattgatgg ttacccacga tcgttatttt ctagatagag
     2101 tagcaaaccg aatcttcgaa ctttcatttg gaaaattata cgagtataaa ggaaattatg
     2161 aagcttacgt cttagaaaaa gcagaacgtg atcgtgtaga agtagaacaa gaagaaaagc
     2221 gcaagcggct ttataaacag gaattagctt ggatgagggc tggcgtacag gcacgtggca
     2281 ccaagcagca agcacggatc aaccgtttcg aagatctaaa ggagaacttg taccaagtaa
     2341 accaagaaga tgatttagag ctgaacctag cgacacaacg tttagggaaa aaagtactgg
     2401 aaatcaaaga tggcagttac cgtataaatg accaaacact gctagaacat ttagatttat
     2461 tgattcaatc tcgggaaaga ctaggtatta ctggtaaaaa tggtgcggga aaatcgacat
     2521 tgcttaatat tctagctggc agaattcccc tggatagcgg tacaatgtct atcggtgaaa
     2581 cggttcatct tgcgtattat acacaagaaa atgaagaaat ggcaccagat aaacggatga
     2641 ttgcttactt acaagaagct gctgaagaag caaaaacagc agatggcagt caaatcggag
     2701 tagcagaatt acttgaacga tttttatttc caagatttat gcatgggaca ctgataggca
     2761 aactttcagg cggagaaaaa cgccggttat ttttgttgaa actgctgatt cagcaaccta
     2821 atgttttatt attggatgaa ccgaccaatg atttggacat agcaacattg acgattttgg
     2881 aagattattt tagaagtttt ccaggtgctg tgatcactgt ttcccatgac cgttatttct
     2941 tggacaaggt agcagataag ttattagtat tccaaggaaa cggaaaacaa gaactttatt
     3001 acggaaacat gtccagttat ttactgaagc aaaaagagac ccagcagcct gctgaaaaag
     3061 cgaaaccaaa aatacagagc aaggaacctg ctgaaaagaa gaaattatct tacatggaac
     3121 aaaaagaatg ggaaacgatt gaagatgaga ttgcagaact tgaagaaaaa atctcattgc
     3181 tccaagaaga gatgaatcat caaggagata atttcactcg attacaagaa ttgcaaaacg
     3241 acgtatctga aacagaagca caacttgaag aaaaaatggc acggtgggaa tacttgagtg
     3301 aatgggtaga agattaggag gaaaaaggat ggaacaagcg tatcttgact taggaagaaa
     3361 attgttggaa gaagggcatc gtaaagaaga cagaacaggc acaggcacat taagcttatt
     3421 cggataccaa atgcggtttg atctgcaaaa agggtttcct ttgttaacaa cgaaacgagt
     3481 accttttgga ttgatcaaaa gcgaattgct ttggttttta aaaggagata cgaatatccg
     3541 ctatctatta caaaataaaa accatatttg ggatgaatgg gcatttgaac gctacatcaa
     3601 aagtccagac tataatggac cagatatgac tgattttggc catagatgtt tgacagatcc
     3661 tgaattcaat gaagaatata aaaagcagag caagcttttt tgcgagaaga tcctaaccga
     3721 tgattccttt gctgaaacat acggcgatct tggacacatc tacggctatc aatggcgtca
     3781 ctgggaaaca aaagacggtg gctttatcga tcaaatcaaa caagtgatcg aagcaatcaa
     3841 aaagactcct gattctagaa gattgatcgt ttctgcatgg aatccggaag atgttcctag
     3901 catggctttg cctccttgtc atacgatgtt tcaattttat gttcaagagg gacggctaag
     3961 ctgccaattg tatcaacgca gtggggatgt gtttctaggc gttccgttca acattgcaag
     4021 ttatgcgttg ctgactcacc taattgcaca tgaaacaggt ttagcggttg gcgaatttgt
     4081 tcacacatta ggagatgctc atctttatat caatcatatc gaacaaatga aagaacaatt
     4141 gagccgagaa atacgcgcat ttccgacttt agttttgaat caggaaaagc agtcagtatt
     4201 tgattttgag atggaagata tccaattaga aggatatgac ccacatccgg cgatcaaagc
     4261 tcctatcgct gtttagaatc agaaaggatg agaaaatgtt agctgcaatt tgggcacagg
     4321 atgaaaacgg attgattgga aaagaagacc gtcttccttg gcgtttgcca aatgatctga
     4381 aattcttcaa acaaatgaca gaagcaaata cactagtgat gggacgaaaa acattcgaag
     4441 ggatgggtag ccgtccgttg ccgaatcgtc agacgattgt tttgacgaga gattcttcct
     4501 ataaagcaga aggcgtgcat gtcatgcata gtgtggaaga cgtgcttgct ctggaaaaag
     4561 aaacagacgg tatctttttc atcgctggag ggtcagctgt ttatcaagaa tttctgccat
     4621 tttgtacgat attataccgt acagtcatcc atcatgtatt cgatggagat gcttattttc
     4681 cacctgttga ctggtctgat tggtcactga tcaatactag tcaaggagaa atggatgaaa
     4741 aaaatcgtta tccgcatcaa tttgaaacgt atcagcgtaa tgagaatcct gtaaaaagcg
     4801 ggacaggcga attgacgata taaaaaagct atggatagac tagctgttat ttagagctgt
     4861 cccatccata gctttatttt ttttattaag taaagaataa aacagagaag tacataaaac
     4921 ctgcacctaa cataacaaac aaatgccaaa caacatgcat atagcggata gaattcaagc
     4981 tataaaagaa tgcgcctatc gtgtaagaaa gcccgcctgc taccatcaaa ataacaccag
     5041 tcattccaag agagtgataa agaggaacag cagccacgac acagagccac cccataaaaa
     5101 tatagatgat cgtagatact tttgatactc tctccagttt atgcaacgtc aacgctttat
     5161 atataatgcc aagaatcgca aacaaccaga ttaatacaaa taaagtccaa cctagccatc
     5221 ctcggatact cagcaaacaa aaaggagtat aacttcctgc aatcaaaaga aaaatcgaac
     5281 tatgatcgaa tacttggaac accttttttg cttttgtaaa aatcaatgaa tgaaacaaag
     5341 tagacgttaa aaataaaaga atcatcatcg atccatagat agcataagag acaatatgga
     5401 gggaggaatg caagtgggca ccttttacta aaagaaccac tagtcccgcg atactcaatc
     5461 cagtcccaat tccatgggtg actgcattaa acacttcatt taatatttca tacgttcgat
     5521 taaatttcgt tttttccatg aaaacggctc ctttactagg tgtaattaat gaaaaatcat
     5581 tatttgtctg ttatactaaa aatagaaatt gtcttacatg tagtttaaca tgaataaggc
     5641 atcttgttaa agaaagagag agagaaaata atgacaaatg taaaaatcgt aacagattct
     5701 tcatgtacga tggaaaaaaa tgtacgcgat gctttaggca ttcgtgtcat gccgctatcc
     5761 atcatgatcg acggaacagt atatcccgat gatgaccaac tagacggcga aagatttatg
     5821 gaaatgatgg cgaaagcaaa aaatctgccc aaaacaagcc aaccaccaat tggagaattc
     5881 atctcgatgt atgatgagct aggagaagac ggcagtgaag tgatttcgat ccatatgaca
     5941 aaaggcttga gtggaacagt agaagcagca agacaagcca gtaatctaac aaaaacgaaa
     6001 gtaacggtta tcgacagtga taccactgac caaggattat cttttcaggt aattcgagca
     6061 gctgaattag caaaagaagg taaaacagta gagaaaatcc ttgaagaagt caaaaaagta
     6121 caagacaata caaaattata catcggaata tccacactag ataacttggt aaaaggtgga
     6181 agaatcagcc gaacaactgg tttgctgtct agtgttttga acatacgcgt ggtgatgaat
     6241 ttcgcccatt ctgaattaat ccctgtaact aaggggcgag gaaagaaaac gttcgataaa
     6301 tggtttaata atttgaaaaa tgaactgaaa gaattgccaa atgtgcgaca aatcggtatt
     6361 tcacatgcgg atgcaaaaga attggcgcaa gaattcaaag agggtttgca agaattattc
     6421 ccggacatgc atatccctgt actgcatacg aatccggtta tcgctacgca tactggtaaa
     6481 gacgcgtttg caatcatgta ttatgtagat tagtcgaaaa gaggataagc cctcagcctg
     6541 aaaggcttgc agcttattct ctttttcttt ataaaattag gaaaataatt gttttctttt
     6601 ttcataaaga ctaccttttt gataaaattt ttgataacat tagaaccaat cgaatacaag
     6661 aggtgaaaaa atgaaattaa cgaaacgaca tttgatcctc gttttgttcc cattattaat
     6721 tgcgatcatc atctatgcag gtttagctgc ttctataccg aaagctggcc cactaatgaa
     6781 accagtaact actgtgagag aagatccaaa taaaaaagaa aaacttcact acatagctat
     6841 cggagattcg ctgactgaag gagtaggaga tcaaaccaag caaggaggat tcgttcccct
     6901 tgtcgcaaat gatctaaaag accgttataa tttgaccgcg gttgaaacag aaaactatgg
     6961 tgtaaatggt gaacgaagtg accagatctt aaagcgagta aaaacaaaag aagaaattcg
     7021 aaacaatatc aaaacagctg attttatcac actgactgtt ggcggtaatg atttgatgaa
     7081 agttatccaa aataatttat tcgggttaac ggtcaattcc tttaaaaagc cactgaaaaa
     7141 ctatcaggaa aatgtcacag aactattgga agaatttcga tccctcaata aaaccgcacc
     7201 tatttacatt ttaggcatct acaatccatt ttatttgaac tttcctgaga tcactgacat
     7261 gcagacaatt gttaacaatt ggaacaaagg aacagaaacg gtgacaaaaa aaatgccgaa
     7321 ctgctacttt atcccaatca atgatttgct ttatcaagga ttgaatcagg aagtaggtgt
     7381 cacagaagaa ggaacagatc aaacaactag cacgacagaa aatctaaatg gcatcaaaaa
     7441 taatgtgctc tatgaagaag atcatttcca tccaaataat ttaggttatc aattgatggc
     7501 aaatgcagtg agagatcagc tgatcgagac acaaaaccaa tggttagaga aggaggatga
     7561 tcaataaaca tgaaaacaag atctgacgta tcttcaaaca aaacaaagaa aacaaattac
     7621 tggaaattcg ccttccttat ccttcttggg gtagtacttg gttcgaccgt atttttaggc
     7681 agccgtattt ttgctaatcg ggaaccagaa ctcccagaaa taccagctct tacggaaaga
     7741 caaggagatc ctgtcttaac gatcaattca aataaagaaa aagtcaatca aatcatcagc
     7801 tttttcctta gtgagtatca aaaagatagt gatattgaat ataaatttta tttggaaaat
     7861 gaagcactac tcaatggtac tttcgaagta ctaggttttc ctatcgattt ctatttatat
     7921 tttgatccgt atgtgatgga aaacggaaat gtccaactaa aagctagaag tctttctatc
     7981 ggaacattga gtttgccaat caaagatgtg atgaatatga tcaagagaaa ctataaatta
     8041 ccagattgga tcgaagtcaa tacagatgat ctgactatca tgcttaggtt ggatcaattc
     8101 cgaatgcaaa acgggatgta tattaaagca gataaaatcg acttagtaaa tgatgacatt
     8161 cggtttagtc tatatttgcc aaaagatacc tctgatgctt caaacaactc aaataccaac
     8221 aaaactagca ccagcagtac tgaaagcaag acaaaagaaa ataaaaaatc atcggatgag
     8281 tagtattaga gggggaatca taatggaacg agcaatattt gcaggaggct gcttctggtg
     8341 tatgatccag cctttcgaca cgcttcctgg tatccataca gtgatgtcag gatatactgg
     8401 agggcatgta ccagatccga cttatgaaca agtaaaaagc caaacgactg gacatacaga
     8461 agcagtggag attatctatg atccaacatt gatttcatat gaacaattag tagaacttta
     8521 ctggcagcaa actgatccaa ctgacgcttt cggacaattc gaggatcgcg gtgacaatta
     8581 tcgcccggtg atcttttatt tgacagaaga acagcggatc attgctgaaa aaagtaagaa
     8641 acagttagct gaaagtggac gtttcgaaca gccaatcgtt acaaaaatcg aaccagccca
     8701 accattttat ctagcagaag aagaccatca agagtattat aaaaagcatc ctgaaaattt
     8761 taaaagaaac catgcacgcc gggctgcctt tatcgaagaa aattggagga acgaagggtg
     8821 aatcgaagct tttttcatta tttaatgaca ctgcgaggcg gtggcacaca tgatgcttta
     8881 tctgttttcg ctacagaagc cggtaaagac atccaatttc ctaagcacag ctctagctac
     8941 gaagaaattt ctaattatct ggaactgaat gtcgactatt tgccgtccat ggatatcttt
     9001 gacgaagcat gggaaaaata tttagaaaat aatcatgaca tataagagat agttttgtac
     9061 tttatgatca aaaaagtttt ttgtccaata gcctaattga aa
//
LOCUS       DADVXB010000333         7959 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.131, whole genome shotgun sequence.
ACCESSION   DADVXB010000333 DADVXB010000000
VERSION     DADVXB010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.131"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            128..1564
                     /locus_tag="KB902_002922"
     CDS             128..1564
                     /locus_tag="KB902_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6809655.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="KB902_002923"
     CDS             1753..4200
                     /locus_tag="KB902_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6809656.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="KB902_002924"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="KB902_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6809657.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="KB902_002925"
     CDS             complement(5690..6793)
                     /locus_tag="KB902_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6809658.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="KB902_002926"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="KB902_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6809659.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1359 c         1729 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DADVXB010000334         6814 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.141, whole genome shotgun sequence.
ACCESSION   DADVXB010000334 DADVXB010000000
VERSION     DADVXB010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.141"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            complement(75..1366)
                     /locus_tag="KB902_002927"
                     /pseudo
     CDS             complement(75..1366)
                     /locus_tag="KB902_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1698..2666
                     /locus_tag="KB902_002928"
     CDS             1698..2666
                     /locus_tag="KB902_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBB6809660.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            2659..3690
                     /gene="vanA"
                     /locus_tag="KB902_002929"
     CDS             2659..3690
                     /gene="vanA"
                     /locus_tag="KB902_002929"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBB6809661.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            3696..4304
                     /locus_tag="KB902_002930"
     CDS             3696..4304
                     /locus_tag="KB902_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBB6809662.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            4732..5643
                     /gene="vanY"
                     /locus_tag="KB902_002931"
     CDS             4732..5643
                     /gene="vanY"
                     /locus_tag="KB902_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBB6809663.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            5796..6281
                     /gene="vanZ"
                     /locus_tag="KB902_002932"
     CDS             5796..6281
                     /gene="vanZ"
                     /locus_tag="KB902_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBB6809664.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(6568..>6814)
                     /locus_tag="KB902_002933"
     CDS             complement(6568..>6814)
                     /locus_tag="KB902_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6809665.1"
                     /translation="NLLVLGKCFSDFSRIKIFYALETYKEMCVCDLAEILTASVATTS
                     HHLRFLKKHGMAKSRQDGKVVYYSLANEDILSAIRVF"
BASE COUNT         2138 a         1182 c         1476 g         2018 t
ORIGIN      
        1 ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag tggatcagtt
       61 cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat gatgcgcaat
      121 ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt gatatggttg
      181 ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt gatttgtggc
      241 agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat gatattattg
      301 gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag aaagtcttga
      361 tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc cacaatatcg
      421 gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata atcaagcttg
      481 cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa ttgatagtgt
      541 ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt gcgaaaggta
      601 cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt tggaaacagc
      661 tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc gaccgcttca
      721 cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg tcggttctcg
      781 acaatgtcca ataagcgctg tgtttgtcca tccatcatga tgaaactcat agcacctgaa
      841 acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg tgtccgaaaa
      901 ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac cgatagattt
      961 ttctgagcgg cgatctctgt cattgaggta tttttttcag acgagtcacg acagaccagc
     1021 ggactttctc actgatgaaa caatgttttt tcgcaacaga agtatctgcg acaaaggtcc
     1081 gctgacaagc tttgcatttg aagcgttgct ttttcaattc gaggtaggta cggtattcag
     1141 aaacatcgtt cattaacaac cggacggttg ttgtacccca acgcacaata tctgaagcaa
     1201 tctggtgttt acagtggatg cattcttggg ctgtataaat caagtttcca cgataaatat
     1261 gacagatttg ccctttgtat ttttcttttg tgagacaatt ttcgttaaaa gtaactgata
     1321 agtctagaat atctaatgtt tctttgataa ggtgagtgta agacatcttg attcctcctt
     1381 ttgggttggt tcgccaaatt aattctaaag gatttcaagg tgtcttttct atatgttttg
     1441 gaaaataaaa aagatgctgg tgtcatccac caacatcaaa aagtatagag ccataatttt
     1501 ttaggaaaat ctcaaggtta tctttacttt ttcttaggaa attaacaatt taatattaag
     1561 aaacggctcg ttcttacacg gtagacttaa taccgtaaga acgagccgtt ttcgttcttc
     1621 agagaaagat ttgacaagat taccattggc atccccgttt tatttggtgc ctttcacaga
     1681 aagggttggt cttaattatg aataacatcg gcattactgt ttatggatgt gagcaggatg
     1741 aggcagatgc attccatgct ctttcgcctc gctttggcgt tatggcaacg ataattaacg
     1801 ccaacgtgtc ggaatccaac gccaaatccg cgcctttcaa tcaatgtatc agtgtgggac
     1861 ataaatcaga gatttccgcc tctattcttc ttgcgctgaa gagagccggt gtgaaatata
     1921 tttctacccg aagcatcggc tgcaatcata tagatacaac tgctgctaag agaatgggca
     1981 tcactgtcga caatgtggcg tactcgccgg atagcgttgc cgattatact atgatgctaa
     2041 ttcttatggc agtacgcaac gtaaaatcga ttgtgcgctc tgtggaaaaa catgatttca
     2101 ggttggacag cgaccgtggc aaggtactca gcgacatgac agttggtgtg gtgggaacgg
     2161 gccagatagg caaagcggtt attgagcggc tgcgaggatt tggatgtaaa gtgttggctt
     2221 atagtcgcag ccgaagtata gaggtaaact atgtaccgtt tgatgagttg ctgcaaaata
     2281 gcgatatcgt tacgcttcat gtgccgctca atacggatac gcactatatt atcagccacg
     2341 aacaaataca gagaatgaag caaggagcat ttcttatcaa tactgggcgc ggtccacttg
     2401 tagataccta tgagttggtt aaagcattag aaaacgggaa actgggcggt gccgcattgg
     2461 atgtattgga aggagaggaa gagtttttct actctgattg cacccaaaaa ccaattgata
     2521 atcaattttt acttaaactt caaagaatgc ctaacgtgat aatcacaccg catacggcct
     2581 attataccga gcaagcgttg cgtgataccg ttgaaaaaac cattaaaaac tgtttggatt
     2641 ttgaaaggag acaggagcat gaatagaata aaagttgcaa tactgtttgg gggttgctca
     2701 gaggagcatg acgtatcggt aaaatctgca atagagatag ccgctaacat taataaagaa
     2761 aaatacgagc cgttatacat tggaattacg aaatctggtg tatggaaaat gtgcgaaaaa
     2821 ccttgcgcgg aatgggaaaa cgacaattgc tattcagctg tactctcgcc ggataaaaaa
     2881 atgcacggat tacttgttaa aaagaaccat gaatatgaaa tcaaccatgt tgatgtagca
     2941 ttttcagctt tgcatggcaa gtcaggtgaa gatggatcca tacaaggtct gtttgaattg
     3001 tccggtatcc cttttgtagg ctgcgatatt caaagctcag caatttgtat ggacaaatcg
     3061 ttgacataca tcgttgcgaa aaatgctggg atagctactc ccgccttttg ggttattaat
     3121 aaagatgata ggccggtggc agctacgttt acctatcctg tttttgttaa gccggcgcgt
     3181 tcaggctcat ccttcggtgt gaaaaaagtc aatagcgcgg acgaattgga ctacgcaatt
     3241 gaatcggcaa gacaatatga cagcaaaatc ttaattgagc aggctgtttc gggctgtgag
     3301 gtcggttgtg cggtattggg aaacagtgcc gcgttagctg ttggcgaggt ggaccaaatc
     3361 aggctgcagt acggaatctt tcgtattcat caggaagtcg agccggaaaa aggctctgaa
     3421 aacgcagtta taaccgttcc cgcagacctt tcagcagagg agcgaggacg gatacaggaa
     3481 acggcaaaaa aaatatataa agcgctcggc tgtagaggtc tagcccgtgt ggatatgttt
     3541 ttacaagata acggccgcat tgtactgaac gaagtcaata ctctgcccgg tttcacgtca
     3601 tacagtcgtt atccccgtat gatggccgct gcaggtattg cacttcccga actgattgac
     3661 cgcttgatcg tattagcgtt aaaggggtga taagcatgga aataggattt acttttttag
     3721 atgaaatagt acacggtgtt cgttgggacg ctaaatatgc cacttgggat aatttcaccg
     3781 gaaaaccggt tgacggttat gaagtaaatc gcattgtagg gacatacgag ttggctgaat
     3841 cgcttttgaa ggcaaaagaa ctggctgcta cccaagggta cggattgctt ctatgggacg
     3901 gttaccgtcc taatcgtgct gtaaactgtt ttatgcaatg ggctgcacag ccggaaaata
     3961 acctgacaaa ggaaagttat tatcccaata ttgaccgaac tgagatgatt tcaaaaggat
     4021 acgtggcttc aaaatcaagc catagccgcg gcagtgccat tgatcttacg ctttatcgat
     4081 tagacacggg tgagcttgta ccaatgggga gccgatttga ttttatggat gaacgctctc
     4141 atcatgcggc aaatggaata tcatgcaatg aagcgcaaaa tcgcagacgt ttgcgctcca
     4201 tcatggaaaa cagtgggttt gaagcatata gcctcgaatg gtggcactat gtattaagag
     4261 acgaaccata ccccaatagc tattttgatt tccccgttaa ataaactttt aaccgttgca
     4321 cggacaaact atataagcta actctttcgg caggaaaccc gacgtatgta actggttctt
     4381 agggaattta tatatagtag atagtattga agatgtaagg cagagcgata ttgcggtcat
     4441 tatctgcgtg cgctgcggca agatagcctg ataataagac tgatcgcata gaggggtggt
     4501 atttcacacc gcccattgtc aacaggcagt tcagcctcgt taaattcagc atgggtatca
     4561 cttatgaaaa ttcatctaca ttggtgataa tagtaaatcc agtagggcga aataattgac
     4621 tgtaatttac ggggcaaaac ggcacaatct caaacgagat tgtgccgttt aaggggaaga
     4681 ttctagaaat atttcatact tccaactata tagttaagga ggagactgaa aatgaagaag
     4741 ttgttttttt tattgttatt gttattctta atatacttag gttatgacta cgttaatgaa
     4801 gcactgtttt ctcaggaaaa agtcgaattt caaaattatg atcaaaatcc caaagaacat
     4861 ttagaaaata gtgggacttc tgaaaatacc caagagaaaa caattacaga agaacaggtt
     4921 tatcaaggaa atctgctatt aatcaatagt aaatatcctg ttcgccaaga aagtgtgaag
     4981 tcagatatcg tgaatttatc taaacatgac gaattaataa atggatacgg gttgcttgat
     5041 agtaatattt atatgtcaaa agaaatagca caaaaatttt cagagatggt caatgatgct
     5101 gtaaagggtg gcgttagtca ttttattatt aatagtggct atcgagactt tgatgagcaa
     5161 agtgtgcttt accaagaaat gggggctgag tatgccttac cagcaggtta tagtgagcat
     5221 aattcaggtt tatcactaga tgtaggatca agcttgacga aaatggaacg agcccctgaa
     5281 ggaaagtgga tagaagaaaa tgcttggaaa tacgggttca ttttacgtta tccagaggac
     5341 aaaacagagt taacaggaat tcaatatgaa ctatggcata ttcgctatgt tggtttacca
     5401 catagtgcga ttatgaaaga aaagaatttc gttctcgagg aatatatgga ttacctaaaa
     5461 gaagaaaaaa ccatttctgt tagtgtaaat ggggaaaaat atgagatctt ttattatcct
     5521 gttactaaaa ataccaccat tcatgtgccg actaatcttc gttatgagat atcaggaaac
     5581 aatatagacg gtgtaattgt gacagtgttt cccggatcaa cacatactaa ttcaaggagg
     5641 taaggatggc ggaatgaaac caacgaaatt aatgaacagc attattgtac tagcactttt
     5701 ggggtaacgt tagcttttta atttaaaacc cacgttaact aggacattgc tatactaatg
     5761 atacaactta aacaaaagaa ttagaggaaa ttatattggg aaaaatatta tctagaggat
     5821 tgctagcttt atatttagtg acactaatct ggttagtgtt attcaaatta caatacaata
     5881 ttttatcagt atttaattat catcaaagaa gtcttaactt gactccattt actgctactg
     5941 ggaatttcag agagatgata gataatgtta taatctttat tccatttggc ttgcttttga
     6001 atgtcaattt taaagaaatc ggatttttac ctaagtttgc ttttgtactg gttttaagtc
     6061 ttacttttga aataattcaa tttatcttcg ctattggagc gacagacata acagatgtaa
     6121 ttacaaatac tgttggaggc tttcttggac tgaaattata tggtttaagc aataagcata
     6181 tgaatcaaaa aaaattagac agagttatta tttttgtagg tatacttttg ctcgtattat
     6241 tgctcgttta ccgtacccat ttaagaataa attacgtgta agatgtctaa atcaagcaat
     6301 ctgatctttc atacacataa agatattgaa tgaattggat tagatggaaa acgggatgtg
     6361 gggaaactcg cccgtaggtg tgaagtgagg ggaaaaccgg tgataaagta aaaagcttac
     6421 ctaacactat agtaacaaag aaagcccaat tatcaatttt agtgctgagg aattggtctc
     6481 tttaataaat ttccttaacg ttgtaaatcc gcattttcct gacggtaccc ccaaactaag
     6541 atttcataga tagattttct gataacttta aaaaacacga atagcggaaa ggatgtcttc
     6601 attcgctaaa gagtaataaa ctacttttcc atcttgacgt gattttgcca ttccatgttt
     6661 ttttaaaaaa cgtaaatggt gtgacgttgt agcgacacta gcagtaagta tttctgctaa
     6721 atcacagacg cacatttcct tataggtttc taaagcatag aaaattttaa ttctagaaaa
     6781 atcgctgaaa catttcccta acacaagtaa gttt
//
LOCUS       DADVXB010000335         6235 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.148, whole genome shotgun sequence.
ACCESSION   DADVXB010000335 DADVXB010000000
VERSION     DADVXB010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.148"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            219..884
                     /locus_tag="KB902_002934"
                     /pseudo
     CDS             219..884
                     /locus_tag="KB902_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            920..1165
                     /locus_tag="KB902_002935"
     CDS             920..1165
                     /locus_tag="KB902_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6809666.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1268..2137
                     /locus_tag="KB902_002936"
     CDS             1268..2137
                     /locus_tag="KB902_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBB6809667.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2118..2852
                     /locus_tag="KB902_002937"
     CDS             2118..2852
                     /locus_tag="KB902_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6809668.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2885..3793
                     /locus_tag="KB902_002938"
     CDS             2885..3793
                     /locus_tag="KB902_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBB6809669.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3790..4332
                     /gene="sat4"
                     /locus_tag="KB902_002939"
     CDS             3790..4332
                     /gene="sat4"
                     /locus_tag="KB902_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBB6809670.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4425..5219
                     /locus_tag="KB902_002940"
                     /note="aph(3')-IIIa"
     CDS             4425..5219
                     /locus_tag="KB902_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBB6809671.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5495..6067
                     /locus_tag="KB902_002941"
     CDS             5495..6067
                     /locus_tag="KB902_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6809672.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         2142 a          928 c         1370 g         1795 t
ORIGIN      
        1 ccgttgtaaa aattggggaa aagggatata ttgattttat ctctttttca aaataaacat
       61 ggggctgacc caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag
      121 tggaaagacc tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata
      181 atataggtga ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa
      241 accaactttg tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg
      301 ccattgtgca gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta
      361 tgggtagacc ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc
      421 aaggggttta ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct
      481 acttatctca agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga
      541 ttatgaacga tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg
      601 gcttaatcag tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata
      661 aatactcttt cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag
      721 cccttgaaaa ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt
      781 taaaggatga actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg
      841 aaaatcaatt aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta
      901 ttaataagga gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga
      961 aactgaaaat ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt
     1021 ggggaatagg atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt
     1081 tagcaaaatg aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta
     1141 taaaaagaca attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg
     1201 ttgagtagaa gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc
     1261 atgcttgatg gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta
     1321 tatagaaggt attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga
     1381 tatagatatc ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt
     1441 cgctacaaag ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg
     1501 tgattggatt aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt
     1561 acgtgatatt aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc
     1621 caattatcag actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc
     1681 gattagcaaa atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga
     1741 aacttatccc aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt
     1801 ctctttaatg tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca
     1861 tgtttttcgt atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg
     1921 tatcaacgaa aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata
     1981 taccgagaag gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga
     2041 catgaccgag aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt
     2101 aaacgaggag agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat
     2161 acagtcaaat gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga
     2221 aaaagatgct acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat
     2281 ggcactgtat atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc
     2341 ataaaatgct cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct
     2401 gtgccataga agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg
     2461 cgtttcatta tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg
     2521 ctggtggcaa tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag
     2581 actggtatta taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg
     2641 agggcaaacg gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga
     2701 ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac
     2761 agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga
     2821 tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat
     2881 gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga
     2941 acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga
     3001 atttcaggat tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga
     3061 tgactggctt aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt
     3121 attcccacct gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat
     3181 tgatcttacc ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat
     3241 aaaggttcta attgataaag attgtagaat taaaagggac atagttccga ctgatataga
     3301 ttatcatgta agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa
     3361 tgtaacacct tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca
     3421 ttttaatcag attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga
     3481 aacaggcttt aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga
     3541 ggatttgtgg gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga
     3601 agcattattt ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct
     3661 tcattatgcc tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa
     3721 aaaatacact ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag
     3781 gcgggaacag tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc
     3841 gaaccatttg aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt
     3901 acagaattac tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag
     3961 gatgaggagg cagattgcct tgaatatatt gacaatactg ataagataat atatctttac
     4021 taccaagacg ataaatgcgt cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct
     4081 tatatagaag atatcgccgt atgtaaggat ttcagggggc aaggcatagg cagcgcgctt
     4141 atcaatatat ctatagaatg ggcaaagcat aaaaacttgc atggactaat gcttgaaacc
     4201 caggacaata accttatagc ttgtaaattc tatcataatt gtggtttcaa aatcggctcc
     4261 gtcgatacta tgttatacgc caactttgaa aacaactttg aaaaagctgt tttctggtat
     4321 ttaaggtttt agaatgcaag gaacagtgaa ttggagttcg tcttgttata attagcttct
     4381 tggggtatct ttaaatactg tagaaaagag gaaggaaata ataaatggct aaaatgagaa
     4441 tatcaccgga attgaaaaaa ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa
     4501 tgtctcctgc taaggtatat aagctggtgg gagaaaatga aaacctatat ttaaaaatga
     4561 cggacagccg gtataaaggg accacctatg atgtggaacg ggaaaaggac atgatgctat
     4621 ggctggaagg aaagctgcct gttccaaagg tcctgcactt tgaacggcat gatggctgga
     4681 gcaatctgct catgagtgag gccgatggcg tcctttgctc ggaagagtat gaagatgaac
     4741 aaagccctga aaagattatc gagctgtatg cggagtgcat caggctcttt cactccatcg
     4801 acatatcgga ttgtccctat acgaatagct tagacagccg cttagccgaa ttggattact
     4861 tactgaataa cgatctggcc gatgtggatt gcgaaaactg ggaagaagac actccattta
     4921 aagatccgcg cgagctgtat gattttttaa agacggaaaa gcccgaagag gaacttgtct
     4981 tttcccacgg cgacctggga gacagcaaca tctttgtgaa agatggcaaa gtaagtggct
     5041 ttattgatct tgggagaagc ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc
     5101 ggtcgatcag ggaggatatc ggggaagaac agtatgtcga gctatttttt gacttactgg
     5161 ggatcaagcc tgattgggag aaaataaaat attatatttt actggatgaa ttgttttagt
     5221 acctagattt agatgtctaa aaagctttaa ctacaagctt tttagacatc taatcttttc
     5281 tgaagtacat ccgcaactgt ccatactctg atgttttata tcttttctaa aagttcgcta
     5341 gatagagttc tatattagag atgtaaagag ttttggtgaa gaggtttgtg agtatggctt
     5401 ttataaccag ggtgcaatga gaagcactaa cagcagctag cttaagaacg cataggatat
     5461 actttttatg gaagtcacag aggaggaata aaatttgaac aggattaaca gagtaacctc
     5521 tattcttatt cagctgcaat caaaaaaaat aattcctgcc aaagaaattg cacagcgatt
     5581 taatataagc ttaaggacag tttacagaga tatccggaca cttgaagaag ccggaatacc
     5641 aattggatct gaggccggaa aaggatattt tcttgtagag ggcttcctac ttccgccggt
     5701 aatgtttaca gcggcggaag tgggtgcatt gattacagca gggaaatttt taaattgcca
     5761 tggagatgaa tcatttataa aggattttga ttcagctatg tataaaatca aatctatttt
     5821 gaagcatggt gaaaaaaact atgcacagga gttggagaac agtattaacg tgtacagcac
     5881 atctggacag aaaaatacat tggcggataa cgttattgca gcaattcaga ctgcaatctg
     5941 caataaaagg gtaatatcaa ttcaatatcc tgcatcagga gggcaagaac cggaaagcag
     6001 aatgatagag cctatatcac tggggtttta tgaacagaac tggtacttaa tcggttttgc
     6061 aggctaagaa atgaatatag gaattttcgt gtggatcgga ttaaaagcat ttgcatagaa
     6121 gaagagctct gtcaaagcca tgatggctct ttggaacaaa tattaaaaca aatgctttca
     6181 tataaaaaac tatatgccct acaatgccgt tgtaaaaatt ggggaaaagg gatat
//
LOCUS       DADVXB010000336         2555 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.204, whole genome shotgun sequence.
ACCESSION   DADVXB010000336 DADVXB010000000
VERSION     DADVXB010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.204"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            <1..459
                     /locus_tag="KB902_002942"
     CDS             <1..459
                     /locus_tag="KB902_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6809673.1"
                     /translation="TLFDSRFKTLQQNLQEDDIIYVTDLTRITRSTQDLFELIDNIRD
                     KKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFK
                     GRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            673..1368
                     /gene="vanR"
                     /locus_tag="KB902_002943"
     CDS             673..1368
                     /gene="vanR"
                     /locus_tag="KB902_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBB6809674.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1346..2500
                     /locus_tag="KB902_002944"
     CDS             1346..2500
                     /locus_tag="KB902_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6809675.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          881 a          454 c          535 g          685 t
ORIGIN      
        1 accttatttg atagtagatt taaaactttg caacagaacc tacaggaaga tgacatcatt
       61 tatgttacag acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat
      121 aacatacgag ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca
      181 gaagataatc catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag
      241 cgagatctta ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag
      301 tttaaaggtc gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag
      361 ctatataaag aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg
      421 gcttcattat acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg
      481 ggcaatattt ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc
      541 gaaaagccct ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg
      601 taaatgctta taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa
      661 agggtgataa ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat
      721 ttggttgaat tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa
      781 gaagcattgg aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt
      841 cccggcacaa gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt
      901 atcatgctga ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg
      961 gatgattata taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag
     1021 ttgcgccgat acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac
     1081 tccggccttg tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc
     1141 cttactccca ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt
     1201 agctccgagc tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac
     1261 accatcaccg tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg
     1321 aaatatataa aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta
     1381 ttccaaacta gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt
     1441 attcgtgttg tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat
     1501 tttggaaaac aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat
     1561 acggaacaat atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg
     1621 tcgcgtcatg ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt
     1681 acttattcag aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca
     1741 aaagctcaac acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga
     1801 acaaagaaaa aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc
     1861 cattatcggt tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc
     1921 aaagtatgtg catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt
     1981 ttttgagatt acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct
     2041 atactatatg ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa
     2101 acaggcggtt attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc
     2161 gagagtcttt aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat
     2221 tgacattacc gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag
     2281 catcccaaaa gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg
     2341 ttcttccgat acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca
     2401 gcatggaggg cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct
     2461 tccagcgatg ccagacttgg ttgataaaag gaggtcctaa gagatgtata taattttggc
     2521 tctttgtcaa atgatgttgg taaagagaaa tctta
//
LOCUS       DADVXB010000337          782 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.281, whole genome shotgun sequence.
ACCESSION   DADVXB010000337 DADVXB010000000
VERSION     DADVXB010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.281"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            28..765
                     /gene="erm(B)"
                     /locus_tag="KB902_002945"
     CDS             28..765
                     /gene="erm(B)"
                     /locus_tag="KB902_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6809676.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          291 a          139 c          122 g          230 t
ORIGIN      
        1 agatgtaatc acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt
       61 ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat
      121 accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt
      181 aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc agaaaaatta
      241 aaactgaaca ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac
      301 aaacagaggt ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa
      361 aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac
      421 aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt
      481 cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc
      541 ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa gctatatacg
      601 tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt
      661 catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta
      721 ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt
      781 tt
//
LOCUS       DADVXB010000338          782 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 362815-19
            SAMEA8426482-rid11941793.guided.282, whole genome shotgun sequence.
ACCESSION   DADVXB010000338 DADVXB010000000
VERSION     DADVXB010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426482
            Sequence Read Archive: ERR5555447
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005895.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005895.1
            Genome Coverage       :: 332x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 08:08:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,946
            CDSs (total)                      :: 2,884
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 31 of 69
            Pseudo Genes (incomplete)         :: 28 of 69
            Pseudo Genes (internal stop)      :: 21 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426482-rid11941793.guided.282"
                     /isolate="362815-19"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2019-08"
     gene            28..765
                     /gene="erm(B)"
                     /locus_tag="KB902_002946"
     CDS             28..765
                     /gene="erm(B)"
                     /locus_tag="KB902_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6809677.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          290 a          138 c          123 g          231 t
ORIGIN      
        1 agatgtaatc acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt
       61 ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat
      121 accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt
      181 aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc agaaaaatta
      241 aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac
      301 aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca aattattaaa
      361 aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac
      421 aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt
      481 cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc
      541 ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa gctatatacg
      601 tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt
      661 catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta
      721 ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt
      781 tt
//
